# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- MAT_Alpha1 PF04769.7 CCD22170.1 - 4.9e-09 35.8 0.1 6e-09 35.5 0.1 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 Macin PF14865.1 CCD22170.1 - 0.008 16.2 0.5 0.015 15.4 0.1 1.6 2 0 0 2 2 2 1 Macin Defensin_2 PF01097.13 CCD22170.1 - 0.17 11.6 1.4 0.31 10.8 1.0 1.4 1 0 0 1 1 1 0 Arthropod defensin Homeobox_KN PF05920.6 CCD22171.1 - 1.8e-06 27.5 0.6 2.2e-05 24.0 0.1 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CCD22171.1 - 5.5e-06 25.9 1.3 5.5e-06 25.9 0.9 1.6 2 0 0 2 2 2 1 Homeobox domain Homez PF11569.3 CCD22171.1 - 0.0027 16.7 0.2 0.006 15.6 0.1 1.6 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez Leuk-A4-hydro_C PF09127.6 CCD22171.1 - 0.035 13.7 1.2 0.18 11.4 0.1 2.1 2 0 0 2 2 2 0 Leukotriene A4 hydrolase, C-terminal PALP PF00291.20 CCD22172.1 - 1.3e-61 208.4 0.0 1.5e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 CCD22172.1 - 0.068 12.6 0.2 0.26 10.6 0.1 2.1 2 1 0 2 2 2 0 Diacylglycerol kinase catalytic domain MRC1 PF09444.5 CCD22174.1 - 2.1e-44 151.3 12.2 2.1e-44 151.3 8.5 7.2 5 1 2 8 8 8 1 MRC1-like domain DUF4055 PF13264.1 CCD22174.1 - 0.0059 16.6 0.9 0.046 13.8 0.6 2.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4055) KH_1 PF00013.24 CCD22175.1 - 0.00025 20.6 0.0 0.0005 19.6 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CCD22175.1 - 0.04 13.5 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 KH domain Siah-Interact_N PF09032.6 CCD22175.1 - 6.1 6.9 10.4 1.8 8.6 3.0 2.5 2 1 0 2 2 2 0 Siah interacting protein, N terminal Equine_IAV_S2 PF06502.6 CCD22176.1 - 0.084 12.7 0.1 0.2 11.5 0.1 1.7 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein LMBR1 PF04791.11 CCD22176.1 - 1.1 7.8 5.1 1.1 7.7 3.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF543 PF04418.7 CCD22177.1 - 7.9e-30 102.6 0.0 9.1e-30 102.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Peptidase_M3 PF01432.15 CCD22178.1 - 5e-148 493.9 0.1 5e-148 493.9 0.1 1.5 2 0 0 2 2 2 1 Peptidase family M3 MT-A70 PF05063.9 CCD22181.1 - 1.5e-13 50.6 0.1 2.8e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 MT-A70 Spb1_C PF07780.7 CCD22182.1 - 5.8e-74 248.2 27.8 5.8e-74 248.2 19.2 3.2 3 1 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.3 CCD22182.1 - 1.9e-53 180.2 21.6 1.9e-53 180.2 15.0 4.8 6 1 1 7 7 7 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 CCD22182.1 - 1.4e-51 175.0 0.1 1.4e-51 175.0 0.1 2.4 3 0 0 3 3 3 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CCD22182.1 - 0.13 12.8 1.2 25 5.4 0.0 3.6 3 0 0 3 3 3 0 Methyltransferase domain PIG-X PF08320.7 CCD22183.1 - 6.3e-42 143.2 0.3 1.1e-41 142.4 0.2 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 ATP_transf PF09830.4 CCD22185.1 - 3e-17 62.1 0.0 7.2e-17 60.9 0.0 1.7 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 CCD22185.1 - 0.0013 19.2 0.1 0.0031 17.9 0.1 1.6 1 0 0 1 1 1 1 HIT domain QCR10 PF09796.4 CCD22186.1 - 0.018 14.6 2.4 0.018 14.6 1.7 1.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Metaviral_G PF09595.5 CCD22186.1 - 0.13 11.8 8.2 0.14 11.7 5.7 1.0 1 0 0 1 1 1 0 Metaviral_G glycoprotein SSP160 PF06933.6 CCD22186.1 - 1.5 6.7 13.1 1.5 6.7 9.1 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Recep_L_domain PF01030.19 CCD22187.1 - 1.1e-09 38.2 18.3 3.5e-05 23.7 0.8 4.9 1 1 3 4 4 4 2 Receptor L domain CTP_transf_2 PF01467.21 CCD22188.1 - 3.9e-06 26.9 0.0 1.6e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Cytidylyltransferase Phage_Treg PF04761.7 CCD22188.1 - 0.083 12.6 0.2 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator DUF1620 PF07774.8 CCD22189.1 - 6.7e-69 231.4 1.3 9.5e-69 230.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1620) Mgr1 PF08602.5 CCD22190.1 - 6.6e-132 439.9 4.7 1e-131 439.2 3.2 1.3 1 1 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit Thioredoxin PF00085.15 CCD22191.1 - 3.5e-58 193.7 2.1 4.5e-29 100.1 0.2 3.8 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 CCD22191.1 - 6.1e-28 97.8 7.1 1.7e-19 70.3 1.4 4.2 2 1 2 4 4 4 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CCD22191.1 - 7.3e-10 39.0 1.9 0.0042 17.2 0.0 3.8 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCD22191.1 - 6.7e-09 35.7 1.0 0.027 14.5 0.0 4.4 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CCD22191.1 - 2.7e-08 33.7 0.0 0.0023 17.9 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 CCD22191.1 - 3.9e-06 26.5 0.7 0.0038 16.8 0.0 3.0 2 1 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 CCD22191.1 - 0.00011 21.7 0.2 0.086 12.3 0.0 2.6 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 CCD22191.1 - 0.0017 17.8 0.8 1.3 8.5 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin DUF1539 PF07560.6 CCD22191.1 - 0.022 14.6 0.1 0.045 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Thioredoxin_4 PF13462.1 CCD22191.1 - 0.091 12.7 4.1 16 5.4 0.0 3.9 4 1 1 5 5 5 0 Thioredoxin Hexokinase_2 PF03727.11 CCD22192.1 - 1.3e-86 289.8 0.0 1.9e-86 289.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCD22192.1 - 2.6e-76 255.5 0.0 4.8e-76 254.6 0.0 1.4 1 0 0 1 1 1 1 Hexokinase PqqD PF05402.7 CCD22192.1 - 0.074 13.0 0.1 0.26 11.3 0.1 1.9 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) CK2S PF15011.1 CCD22192.1 - 0.078 12.7 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Casein Kinase 2 substrate Oxidored_FMN PF00724.15 CCD22193.1 - 7.4e-125 416.4 0.0 8.4e-125 416.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family WD40 PF00400.27 CCD22194.1 - 6.1e-20 70.3 4.9 0.0064 16.3 0.2 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat ATG22 PF11700.3 CCD22195.1 - 1.4e-151 505.2 25.1 2.2e-151 504.5 17.4 1.3 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 CCD22195.1 - 3.2e-08 32.6 31.4 1.3e-06 27.3 11.0 3.9 2 1 1 3 3 3 3 Major Facilitator Superfamily La PF05383.12 CCD22196.1 - 3.5e-21 74.7 0.3 7.6e-21 73.6 0.1 1.7 2 0 0 2 2 2 1 La domain Hus1 PF04005.7 CCD22197.1 - 3.4 6.5 9.6 0.88 8.4 3.1 2.4 3 1 1 4 4 4 0 Hus1-like protein GAGA_bind PF06217.7 CCD22197.1 - 6 6.7 16.8 3.1 7.6 7.8 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Glutaredoxin PF00462.19 CCD22198.1 - 6.9e-13 48.3 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 CCD22198.1 - 0.00049 19.8 0.0 0.00072 19.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 CCD22198.1 - 0.0069 15.9 0.0 0.0079 15.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 CCD22198.1 - 0.065 13.2 0.8 0.3 11.0 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin MafB19-deam PF14437.1 CCD22198.1 - 0.13 11.8 0.0 5.3 6.6 0.0 2.1 1 1 1 2 2 2 0 MafB19-like deaminase GAT PF03127.9 CCD22199.1 - 0.001 18.9 0.1 0.003 17.4 0.0 1.8 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 CCD22199.1 - 0.0065 16.1 0.2 0.014 15.0 0.1 1.6 1 0 0 1 1 1 1 VHS domain SelR PF01641.13 CCD22200.1 - 6.7e-50 167.9 0.6 6.7e-50 167.9 0.4 1.4 2 0 0 2 2 2 1 SelR domain GFA PF04828.9 CCD22200.1 - 0.0076 16.1 0.7 0.33 10.9 0.1 2.3 1 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme HECT_2 PF09814.4 CCD22200.1 - 0.025 13.2 0.4 4.5 5.8 0.1 2.0 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding zf-H2C2_2 PF13465.1 CCD22200.1 - 0.12 12.6 1.4 3.4 8.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Yippee-Mis18 PF03226.9 CCD22200.1 - 0.17 11.9 1.5 1.1 9.3 1.0 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DNA_RNApol_7kD PF03604.8 CCD22200.1 - 0.54 9.7 4.1 15 5.1 0.3 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_recom PF13408.1 CCD22200.1 - 0.6 10.4 3.6 4.5 7.5 0.3 2.4 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-Mss51 PF13824.1 CCD22200.1 - 2 8.3 7.4 4.8 7.1 0.3 3.4 2 1 2 4 4 4 0 Zinc-finger of mitochondrial splicing suppressor 51 Ste50p-SAM PF09235.5 CCD22201.1 - 3e-22 78.4 4.0 6.2e-22 77.4 2.8 1.5 1 0 0 1 1 1 1 Ste50p, sterile alpha motif RA PF00788.18 CCD22201.1 - 1.7e-15 57.2 0.6 3.9e-15 56.1 0.4 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Rabaptin PF03528.10 CCD22201.1 - 0.63 9.9 7.8 0.3 11.0 3.3 1.9 2 0 0 2 2 2 0 Rabaptin RRP7 PF12923.2 CCD22202.1 - 8.5e-30 103.4 7.5 1.9e-29 102.3 5.2 1.6 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) Voldacs PF03517.8 CCD22202.1 - 0.03 14.1 0.1 0.053 13.3 0.1 1.4 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling DUF45 PF01863.12 CCD22202.1 - 1.9 8.1 6.3 1.8 8.2 3.0 1.8 1 1 1 2 2 2 0 Protein of unknown function DUF45 Histidinol_dh PF00815.15 CCD22203.1 - 1.9e-184 613.0 1.5 2.6e-184 612.6 1.1 1.2 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 CCD22203.1 - 3.2e-28 97.1 0.1 6.6e-28 96.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 CCD22203.1 - 1.8e-11 44.1 1.7 3.3e-11 43.3 0.1 2.4 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase CAP_GLY PF01302.20 CCD22204.1 - 6.8e-16 57.7 0.2 1.3e-15 56.8 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF3373 PF11853.3 CCD22204.1 - 0.0085 14.6 1.7 0.0085 14.6 1.2 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3373) Thioredoxin_7 PF13899.1 CCD22204.1 - 0.011 15.7 0.1 0.032 14.2 0.1 1.9 1 0 0 1 1 1 0 Thioredoxin-like AAA_27 PF13514.1 CCD22204.1 - 0.11 10.1 22.3 0.19 9.3 15.4 1.3 1 0 0 1 1 1 0 AAA domain HAUS-augmin3 PF14932.1 CCD22204.1 - 0.17 11.0 35.4 0.022 13.9 7.2 2.4 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 PspA_IM30 PF04012.7 CCD22204.1 - 0.63 9.3 25.7 0.76 9.0 10.6 2.7 1 1 1 2 2 2 0 PspA/IM30 family MscS_porin PF12795.2 CCD22204.1 - 0.99 8.6 37.1 0.098 11.9 3.1 3.1 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain SH3_9 PF14604.1 CCD22206.1 - 1.3e-06 27.9 0.0 2.9e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.5 CCD22206.1 - 8.9e-05 21.7 0.0 0.00024 20.3 0.0 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SH3_1 PF00018.23 CCD22206.1 - 0.0023 17.2 0.0 0.01 15.1 0.0 2.2 1 1 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCD22206.1 - 0.009 15.4 0.1 0.021 14.3 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Nitroreductase PF00881.19 CCD22207.1 - 2.6e-07 30.6 0.0 3.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family MC1 PF05854.6 CCD22207.1 - 0.061 13.2 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 Nitroreductase PF00881.19 CCD22208.1 - 3.9e-07 30.0 0.0 5.7e-07 29.5 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family Sars6 PF12133.3 CCD22209.1 - 0.0025 17.4 0.2 0.0041 16.7 0.2 1.3 1 0 0 1 1 1 1 Open reading frame 6 from SARS coronavirus VirB3 PF05101.8 CCD22209.1 - 0.11 12.5 0.2 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Type IV secretory pathway, VirB3-like protein Per1 PF04080.8 CCD22210.1 - 1.6e-94 316.2 21.4 2.2e-94 315.8 14.8 1.2 1 0 0 1 1 1 1 Per1-like Spindle_Spc25 PF08234.7 CCD22211.1 - 3e-16 59.1 0.2 3e-16 59.1 0.1 2.3 3 0 0 3 3 3 1 Chromosome segregation protein Spc25 APG6 PF04111.7 CCD22211.1 - 0.0023 17.0 18.3 0.0023 17.0 12.7 1.7 1 1 1 2 2 2 1 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 CCD22211.1 - 0.0037 17.2 3.9 0.0037 17.2 2.7 2.8 2 1 1 3 3 3 1 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.3 CCD22211.1 - 0.021 14.6 3.8 0.021 14.6 2.6 2.8 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Laminin_II PF06009.7 CCD22211.1 - 0.038 13.7 8.9 0.032 13.9 4.7 1.9 1 1 1 2 2 2 0 Laminin Domain II DUF272 PF03312.10 CCD22211.1 - 0.14 12.4 2.1 0.42 10.8 1.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF272) Ribosomal_S3_C PF00189.15 CCD22211.1 - 0.19 11.9 1.2 0.56 10.4 0.9 1.9 1 1 0 1 1 1 0 Ribosomal protein S3, C-terminal domain DUF4140 PF13600.1 CCD22211.1 - 0.27 11.7 8.2 0.63 10.5 0.1 2.8 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF2576 PF10845.3 CCD22211.1 - 0.47 9.6 0.0 0.47 9.6 0.0 2.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2576) TMF_TATA_bd PF12325.3 CCD22211.1 - 0.71 9.6 18.8 1 9.1 11.5 2.2 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TEX12 PF15219.1 CCD22211.1 - 0.91 9.5 6.7 15 5.5 0.1 3.2 3 0 0 3 3 3 0 Testis-expressed 12 DUF3373 PF11853.3 CCD22211.1 - 1.1 7.7 6.9 1.4 7.3 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) zf-C4H2 PF10146.4 CCD22211.1 - 2.7 7.9 18.0 4.2 7.3 12.5 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein OmpH PF03938.9 CCD22211.1 - 3.2 7.6 20.4 0.96 9.3 4.6 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) CENP-F_leu_zip PF10473.4 CCD22211.1 - 3.3 7.5 24.1 25 4.7 15.3 2.6 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4163 PF13739.1 CCD22211.1 - 4.1 8.2 6.8 0.98 10.2 0.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) Cortex-I_coil PF09304.5 CCD22211.1 - 4.5 7.3 18.0 4.4 7.3 8.3 3.0 1 1 2 3 3 3 0 Cortexillin I, coiled coil Snapin_Pallidin PF14712.1 CCD22211.1 - 5.3 7.4 20.1 1.7 9.0 2.8 2.9 3 0 0 3 3 3 0 Snapin/Pallidin DUF4337 PF14235.1 CCD22211.1 - 5.5 6.7 11.4 2 8.2 0.6 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4337) DUF848 PF05852.6 CCD22211.1 - 5.5 6.8 17.9 2.8 7.7 3.0 2.3 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Nup54 PF13874.1 CCD22211.1 - 8.2 6.0 19.8 0.5 10.0 5.5 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 ADIP PF11559.3 CCD22211.1 - 9.8 6.0 22.2 1.9 8.3 8.2 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Exo_endo_phos PF03372.18 CCD22212.1 - 5e-18 65.9 0.0 7.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PsbX PF06596.6 CCD22212.1 - 0.0042 16.7 3.2 0.0096 15.5 2.2 1.6 1 0 0 1 1 1 1 Photosystem II reaction centre X protein (PsbX) Yip1 PF04893.12 CCD22212.1 - 0.013 14.9 7.1 0.013 14.9 4.9 1.5 2 0 0 2 2 2 0 Yip1 domain DUF2207 PF09972.4 CCD22212.1 - 0.061 11.9 0.1 0.085 11.4 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF805 PF05656.9 CCD22212.1 - 0.084 12.7 3.8 0.14 11.9 2.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Glyco_transf_28 PF03033.15 CCD22213.1 - 5.8e-28 97.3 0.0 1.3e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 CCD22213.1 - 2.5e-22 78.1 0.6 2.2e-17 62.3 0.1 3.8 4 0 0 4 4 4 2 GRAM domain UDPGT PF00201.13 CCD22213.1 - 1.3e-08 33.8 0.0 2.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 CCD22213.1 - 0.00037 19.7 0.0 0.00075 18.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 CCD22213.1 - 0.022 14.4 0.0 0.085 12.5 0.0 2.0 1 1 1 2 2 2 0 Glycosyltransferase family 28 C-terminal domain DUF2585 PF10755.4 CCD22213.1 - 0.068 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2585) ABC_membrane PF00664.18 CCD22214.1 - 7.7e-55 186.2 8.0 1e-54 185.8 5.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CCD22214.1 - 4.5e-30 104.7 0.0 1.1e-29 103.5 0.0 1.7 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CCD22214.1 - 4.7e-06 25.9 0.8 0.00089 18.5 0.0 2.5 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCD22214.1 - 2.7e-05 24.2 0.0 6e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CCD22214.1 - 0.00012 22.9 0.0 0.00025 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCD22214.1 - 0.0014 18.9 0.0 0.014 15.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 CCD22214.1 - 0.0017 17.0 0.0 0.0027 16.3 0.0 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 CCD22214.1 - 0.0028 17.1 0.0 0.0079 15.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CCD22214.1 - 0.0032 16.5 0.0 0.0063 15.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DUF87 PF01935.12 CCD22214.1 - 0.0088 15.8 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_22 PF13401.1 CCD22214.1 - 0.01 15.9 0.0 0.047 13.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCD22214.1 - 0.02 14.1 0.0 0.049 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_21 PF13304.1 CCD22214.1 - 0.021 14.7 2.8 3.1 7.6 2.0 2.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCD22214.1 - 0.032 14.1 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Phage_int_SAM_1 PF02899.12 CCD22214.1 - 0.041 14.0 1.0 0.2 11.7 0.2 2.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain FtsK_SpoIIIE PF01580.13 CCD22214.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 CCD22214.1 - 0.073 12.4 0.2 0.28 10.6 0.0 2.1 3 0 0 3 3 3 0 AAA-like domain MobB PF03205.9 CCD22214.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PH PF00169.24 CCD22215.1 - 1.8e-06 28.0 0.4 7.4e-06 26.1 0.1 2.2 2 0 0 2 2 2 1 PH domain BLOC1_2 PF10046.4 CCD22215.1 - 0.16 12.0 2.9 0.1 12.7 0.4 1.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L37e PF01907.14 CCD22216.1 - 2e-26 91.5 11.8 2e-26 91.5 8.2 1.5 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 CCD22216.1 - 0.00081 19.1 1.6 0.0012 18.5 1.1 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 CCD22216.1 - 0.02 14.5 0.3 0.026 14.1 0.2 1.4 1 1 0 1 1 1 0 SelR domain zinc_ribbon_6 PF14599.1 CCD22216.1 - 0.13 12.0 1.6 0.2 11.4 1.1 1.2 1 0 0 1 1 1 0 Zinc-ribbon zf-C3HC4_2 PF13923.1 CCD22216.1 - 1.5 8.9 4.3 2.3 8.3 3.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2256 PF10013.4 CCD22216.1 - 2.5 7.9 5.0 3.2 7.5 0.4 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) FHA PF00498.21 CCD22217.1 - 3.7e-08 33.3 0.1 1.9e-07 31.1 0.0 2.4 1 0 0 1 1 1 1 FHA domain Erp_C PF06780.6 CCD22217.1 - 0.00079 19.2 0.0 0.0021 17.9 0.0 1.8 1 0 0 1 1 1 1 Erp protein C-terminus DUF724 PF05266.9 CCD22217.1 - 0.058 13.0 0.3 0.18 11.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Ank_2 PF12796.2 CCD22218.1 - 1.6e-13 50.7 0.8 1.7e-05 25.0 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCD22218.1 - 3.8e-12 46.0 5.0 2.1e-06 27.7 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD22218.1 - 8.7e-12 44.0 1.2 2e-05 24.3 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 CCD22218.1 - 3.8e-11 42.1 1.1 7.3e-05 22.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CCD22218.1 - 3.5e-08 33.7 2.5 0.0052 17.2 0.0 4.9 3 2 2 5 5 5 3 Ankyrin repeats (many copies) FTA4 PF13093.1 CCD22218.1 - 0.72 9.2 16.6 0.4 10.0 7.4 2.6 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 IncA PF04156.9 CCD22218.1 - 1.2 8.6 11.7 0.6 9.6 5.8 2.1 2 0 0 2 2 2 0 IncA protein DUF883 PF05957.8 CCD22218.1 - 1.7 9.0 4.4 0.66 10.4 0.7 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Syntaxin-6_N PF09177.6 CCD22218.1 - 4.6 7.7 9.8 8.6 6.8 2.9 3.3 2 1 1 3 3 3 0 Syntaxin 6, N-terminal UPF0449 PF15136.1 CCD22218.1 - 9.5 6.5 9.9 15 5.8 0.4 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 AA_permease PF00324.16 CCD22219.1 - 9.5e-137 456.2 47.1 1.1e-136 456.0 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD22219.1 - 7.6e-29 100.4 56.9 1.4e-28 99.6 39.5 1.4 1 1 0 1 1 1 1 Amino acid permease Nitroreductase PF00881.19 CCD22220.1 - 6.8e-09 35.7 0.0 8.2e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Nitroreductase PF00881.19 CCD22221.1 - 5.4e-07 29.5 0.0 7.9e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Nitroreductase family AA_permease PF00324.16 CCD22222.1 - 3.9e-127 424.4 34.2 4.5e-127 424.2 23.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD22222.1 - 3.7e-32 111.4 33.1 4.5e-32 111.1 22.9 1.0 1 0 0 1 1 1 1 Amino acid permease Colicin_im PF03857.8 CCD22222.1 - 0.14 11.8 1.3 0.4 10.4 0.9 1.7 1 0 0 1 1 1 0 Colicin immunity protein Rad60-SLD PF11976.3 CCD22223.1 - 8.5e-20 70.2 0.3 1.3e-19 69.6 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CCD22223.1 - 4.6e-12 45.1 0.0 5.9e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.20 CCD22224.1 - 4.3e-73 245.6 0.1 2.8e-72 242.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22224.1 - 3.2e-36 124.7 0.0 9.3e-36 123.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD22224.1 - 5e-05 22.3 0.7 9.1e-05 21.5 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCD22224.1 - 1.2 8.8 3.3 0.39 10.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Homeobox PF00046.24 CCD22225.1 - 1.7e-13 49.9 0.9 2.9e-13 49.2 0.7 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCD22225.1 - 0.00023 20.7 0.1 0.00044 19.8 0.1 1.7 1 1 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 CCD22225.1 - 0.014 14.3 0.2 0.026 13.5 0.1 1.6 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez RNase_H2_suC PF08615.6 CCD22226.1 - 2.5e-06 27.3 0.1 3.9e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) DnaI_N PF07319.6 CCD22226.1 - 0.046 13.9 0.3 0.091 13.0 0.2 1.6 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus MTS PF05175.9 CCD22226.1 - 0.056 12.8 0.1 0.069 12.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain RasGEF PF00617.14 CCD22227.1 - 1.6e-48 164.9 6.7 8e-48 162.6 4.7 2.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCD22227.1 - 2e-16 59.9 0.9 2e-16 59.9 0.6 5.0 5 0 0 5 5 5 1 RasGEF N-terminal motif SH3_1 PF00018.23 CCD22227.1 - 4.1e-07 29.2 0.0 1.2e-06 27.7 0.0 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCD22227.1 - 0.0013 18.1 0.1 0.012 15.1 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 CCD22227.1 - 0.0024 17.3 0.1 0.0051 16.3 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SPX PF03105.14 CCD22228.1 - 2.9e-39 135.5 32.7 8.5e-39 133.9 22.6 1.8 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CCD22228.1 - 1.7e-19 70.0 31.5 2.3e-19 69.6 21.8 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CCD22228.1 - 3.8e-13 48.7 31.5 3.7e-12 45.5 21.7 2.0 1 1 0 1 1 1 1 Citrate transporter PfkB PF00294.19 CCD22229.1 - 1.2e-44 152.7 0.3 2.2e-44 151.7 0.2 1.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CCD22229.1 - 0.033 13.3 1.5 1 8.4 0.2 2.7 2 1 0 2 2 2 0 Phosphomethylpyrimidine kinase RNase_PH PF01138.16 CCD22230.1 - 3.1e-26 92.2 1.4 3.6e-24 85.5 0.2 3.1 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 ELO PF01151.13 CCD22231.1 - 3.3e-59 200.1 22.3 4e-59 199.9 15.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Myb_DNA-binding PF00249.26 CCD22232.1 - 3.6e-16 58.9 0.0 2.5e-08 33.8 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCD22232.1 - 0.00036 20.5 7.0 0.039 14.0 0.3 4.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Beach PF02138.13 CCD22233.1 - 2.5e-110 368.1 2.1 5.4e-110 367.0 1.5 1.6 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 CCD22233.1 - 1.8e-08 34.1 0.1 1.1e-07 31.5 0.1 2.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Ribosomal_S11 PF00411.14 CCD22234.1 - 2.4e-40 137.1 1.0 2.9e-40 136.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Ribosomal_L39 PF00832.15 CCD22235.1 - 3.6e-22 77.5 12.1 4.3e-22 77.2 8.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Mannosyl_trans3 PF11051.3 CCD22236.1 - 3.9e-85 285.4 0.0 5.5e-85 284.9 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 CCD22236.1 - 0.0002 20.8 0.1 0.00045 19.6 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 8 SSB PF00436.20 CCD22237.1 - 4.2e-18 65.1 0.0 5.4e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family MFS_1 PF07690.11 CCD22238.1 - 2.3e-28 98.9 17.9 3.1e-28 98.4 12.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily VIT1 PF01988.14 CCD22238.1 - 3.7 6.9 8.9 0.099 12.1 0.2 2.5 3 0 0 3 3 3 0 VIT family HdeA PF06411.6 CCD22239.1 - 0.44 10.5 1.8 0.85 9.6 0.1 2.3 3 0 0 3 3 3 0 HdeA/HdeB family Ribosomal_L22 PF00237.14 CCD22240.1 - 4.6e-33 113.3 0.2 4.6e-33 113.3 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Fis1_TPR_C PF14853.1 CCD22240.1 - 0.033 14.0 0.1 11 6.0 0.0 2.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat CRT10 PF08728.5 CCD22240.1 - 0.063 11.2 0.2 0.065 11.2 0.2 1.1 1 0 0 1 1 1 0 CRT10 CASP_C PF08172.7 CCD22241.1 - 1.7e-68 230.3 6.5 1.7e-68 230.3 4.5 5.2 2 1 2 4 4 4 1 CASP C terminal STE3 PF02076.10 CCD22242.1 - 3.8e-96 321.5 21.7 4.6e-96 321.2 15.1 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF2516 PF10724.4 CCD22242.1 - 0.22 11.5 0.1 0.22 11.5 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF2516) Helicase_C PF00271.26 CCD22243.1 - 2.8e-12 46.2 0.0 9.5e-12 44.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD22243.1 - 0.00012 21.6 0.0 0.00025 20.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2401 PF10287.4 CCD22244.1 - 7.4e-92 307.0 2.8 1e-91 306.6 2.0 1.2 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CCD22244.1 - 8.2e-27 93.1 0.1 2.2e-26 91.7 0.0 1.8 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) SpoIIIAH PF12685.2 CCD22245.1 - 0.0082 15.6 2.9 0.037 13.5 0.7 2.5 2 0 0 2 2 2 1 SpoIIIAH-like protein Zip PF02535.17 CCD22246.1 - 7.1e-26 90.9 13.1 7.1e-26 90.9 9.1 2.6 1 1 1 2 2 2 1 ZIP Zinc transporter Mem_trans PF03547.13 CCD22246.1 - 0.0011 17.3 0.4 0.0011 17.3 0.3 2.1 2 1 0 2 2 2 1 Membrane transport protein AA_permease PF00324.16 CCD22247.1 - 7e-85 285.1 39.7 8.6e-85 284.8 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD22247.1 - 1.3e-36 126.1 47.8 1.7e-36 125.7 33.1 1.1 1 0 0 1 1 1 1 Amino acid permease IncA PF04156.9 CCD22247.1 - 0.069 12.7 0.2 0.069 12.7 0.1 3.3 4 1 0 4 4 4 0 IncA protein DUF1129 PF06570.6 CCD22247.1 - 0.73 9.1 21.8 0.029 13.6 2.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) GTP_EFTU PF00009.22 CCD22248.1 - 1.3e-36 125.8 0.0 2e-36 125.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CCD22248.1 - 1.4e-15 56.9 0.0 3.1e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.13 CCD22248.1 - 1.2e-14 53.8 0.0 2.5e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.20 CCD22248.1 - 2.2e-08 34.1 0.0 5e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCD22248.1 - 3.4e-06 26.9 0.0 1.3e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 CCD22248.1 - 7.7e-05 23.1 0.1 0.00072 20.0 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein Dynamin_N PF00350.18 CCD22248.1 - 0.0032 17.2 0.1 0.9 9.3 0.0 2.5 1 1 1 2 2 2 2 Dynamin family EFG_II PF14492.1 CCD22248.1 - 0.0045 16.8 0.0 0.017 14.9 0.0 1.9 2 0 0 2 2 2 1 Elongation Factor G, domain II Ras PF00071.17 CCD22248.1 - 0.04 13.3 0.1 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Ras family Bin3 PF06859.7 CCD22248.1 - 0.041 13.8 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) polyprenyl_synt PF00348.12 CCD22249.1 - 5e-81 271.3 0.0 6e-81 271.1 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.20 CCD22250.1 - 2.2e-42 145.0 0.0 1.3e-25 90.0 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22250.1 - 3.1e-21 75.6 0.0 6.7e-15 54.8 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Ribosomal_L14 PF00238.14 CCD22251.1 - 2.2e-41 140.4 2.2 2.5e-41 140.2 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Glyco_transf_56 PF07429.6 CCD22251.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 Pkinase PF00069.20 CCD22252.1 - 7.1e-50 169.5 0.1 1.1e-49 169.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22252.1 - 6.4e-20 71.3 0.0 1.4e-19 70.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CCD22252.1 - 0.073 12.6 1.7 0.18 11.3 0.1 2.4 3 0 0 3 3 3 0 Choline/ethanolamine kinase Kdo PF06293.9 CCD22252.1 - 0.085 11.9 0.1 0.2 10.6 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD22252.1 - 0.25 11.0 0.1 0.44 10.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family L51_S25_CI-B8 PF05047.11 CCD22253.1 - 6.3e-14 51.4 0.1 1.2e-13 50.6 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Pkinase PF00069.20 CCD22254.1 - 2e-71 240.2 0.0 3e-71 239.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22254.1 - 1.9e-40 138.6 0.0 2.7e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD22254.1 - 1.8e-05 23.8 0.0 2.7e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCD22254.1 - 0.053 13.2 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.11 CCD22255.1 - 6.7e-20 71.1 17.0 2e-13 49.8 7.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily PigN PF04987.9 CCD22256.1 - 1.3e-130 435.9 49.2 1.8e-130 435.5 34.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 CCD22256.1 - 8.5e-16 58.2 0.7 3.2e-11 43.1 0.0 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CCD22256.1 - 1.4e-10 40.8 0.1 2.7e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 CCD22256.1 - 0.00032 20.1 0.0 0.00058 19.3 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily PIR PF00399.14 CCD22257.1 - 1.3e-68 224.2 134.5 1.6e-08 33.5 4.4 9.8 10 0 0 10 10 10 9 Yeast PIR protein repeat HCV_NS5a_1a PF08300.8 CCD22257.1 - 0.0063 16.3 3.7 35 4.3 0.0 4.5 1 1 5 6 6 6 1 Hepatitis C virus non-structural 5a zinc finger domain DUF2807 PF10988.3 CCD22257.1 - 0.02 14.4 21.9 0.48 9.9 5.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2807) PIR PF00399.14 CCD22258.1 - 1.6e-60 198.5 128.7 5.6e-08 31.8 3.7 10.6 6 4 4 10 10 10 9 Yeast PIR protein repeat TPR_19 PF14559.1 CCD22258.1 - 0.025 14.8 7.7 0.28 11.5 0.8 3.1 1 1 3 4 4 4 0 Tetratricopeptide repeat HTH_37 PF13744.1 CCD22258.1 - 0.071 12.9 5.9 14 5.5 0.2 3.9 1 1 3 4 4 4 0 Helix-turn-helix domain THDPS_N_2 PF14805.1 CCD22258.1 - 0.25 11.2 9.8 7.7 6.4 0.3 3.9 1 1 3 4 4 4 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal GerPB PF10803.3 CCD22258.1 - 0.33 10.7 12.7 6.5 6.6 0.2 4.2 3 1 2 5 5 5 0 Spore germination GerPB DUF3412 PF11892.3 CCD22258.1 - 0.74 9.6 5.8 8.6 6.2 0.1 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF3412) Apo-CIII PF05778.7 CCD22258.1 - 3.9 6.9 24.0 6 6.3 0.6 5.1 1 1 4 5 5 5 0 Apolipoprotein CIII (Apo-CIII) Dak1_2 PF13684.1 CCD22258.1 - 8.9 5.1 19.9 2.9 6.7 3.8 2.1 1 1 1 2 2 2 0 Dihydroxyacetone kinase family Vps35 PF03635.12 CCD22259.1 - 4.7e-252 838.5 29.8 5.6e-252 838.2 20.6 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 peroxidase PF00141.18 CCD22260.1 - 1.4e-42 145.7 0.0 3.2e-42 144.5 0.0 1.6 1 1 0 1 1 1 1 Peroxidase Cas_DxTHG PF09455.5 CCD22260.1 - 0.028 13.5 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Pam17 PF08566.5 CCD22261.1 - 6.2e-72 240.9 0.1 7.5e-72 240.6 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 DUF1086 PF06461.6 CCD22261.1 - 0.0076 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) Zn_clus PF00172.13 CCD22262.1 - 7.1e-07 29.0 10.2 1.7e-06 27.8 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Las1 PF04031.8 CCD22263.1 - 1.1e-45 155.0 1.7 1.7e-45 154.4 0.1 2.0 2 0 0 2 2 2 1 Las1-like RNA_polI_A34 PF08208.6 CCD22264.1 - 2.7e-32 112.0 18.9 2.7e-32 112.0 13.1 1.6 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 TFIIE_beta PF02186.10 CCD22265.1 - 4.8e-21 74.5 1.0 1.1e-20 73.3 0.7 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF1987 PF09345.5 CCD22265.1 - 0.065 13.0 0.1 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) LexA_DNA_bind PF01726.11 CCD22265.1 - 0.065 12.8 0.1 0.4 10.2 0.0 2.3 2 0 0 2 2 2 0 LexA DNA binding domain RNA_pol_Rpb4 PF03874.11 CCD22266.1 - 1.6e-33 115.1 17.5 1.1e-30 105.9 12.1 2.7 1 1 0 1 1 1 1 RNA polymerase Rpb4 BLVR PF06375.6 CCD22266.1 - 0.027 14.3 10.2 0.047 13.5 7.1 1.4 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Rtf2 PF04641.7 CCD22266.1 - 0.054 12.6 9.7 0.074 12.2 6.7 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Pox_Ag35 PF03286.9 CCD22266.1 - 0.23 10.9 16.3 0.31 10.5 10.9 1.4 1 1 0 1 1 1 0 Pox virus Ag35 surface protein TFIIA PF03153.8 CCD22266.1 - 0.24 11.2 19.7 0.32 10.8 13.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IncFII_repA PF02387.10 CCD22266.1 - 0.59 9.2 14.0 0.56 9.3 8.9 1.5 2 0 0 2 2 2 0 IncFII RepA protein family Peptidase_S49_N PF08496.5 CCD22266.1 - 7.1 6.3 9.7 14 5.4 6.7 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Glyco_transf_15 PF01793.11 CCD22267.1 - 3.4e-90 302.3 17.3 1.1e-66 225.0 5.5 2.1 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase Metallophos PF00149.23 CCD22268.1 - 1.5e-15 57.1 1.7 3e-15 56.1 1.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCD22268.1 - 0.013 15.3 0.0 0.056 13.2 0.0 1.9 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain DUF912 PF06024.7 CCD22268.1 - 0.017 15.1 3.3 4.1 7.5 0.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SAS4 PF15460.1 CCD22269.1 - 1.4e-31 108.3 4.2 1.4e-31 108.3 2.9 2.2 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 Nipped-B_C PF12830.2 CCD22270.1 - 2.3e-40 138.2 3.6 1.5e-39 135.5 0.1 3.7 4 0 0 4 4 4 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 CCD22270.1 - 4.8e-15 55.1 2.1 2.4e-13 49.7 1.0 2.8 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Alba PF01918.16 CCD22270.1 - 0.0062 16.0 0.8 1.3 8.7 0.1 3.0 2 0 0 2 2 2 2 Alba HEAT_2 PF13646.1 CCD22270.1 - 0.052 13.8 0.0 2.6 8.3 0.0 3.1 2 0 0 2 2 2 0 HEAT repeats PXA PF02194.10 CCD22271.1 - 2.5e-11 43.4 2.5 8.1e-11 41.8 1.8 1.9 1 1 0 1 1 1 1 PXA domain Bac_DnaA PF00308.13 CCD22271.1 - 0.035 13.7 0.5 0.1 12.2 0.3 1.7 1 0 0 1 1 1 0 Bacterial dnaA protein PCI PF01399.22 CCD22272.1 - 0.00047 20.4 0.4 0.00071 19.8 0.3 1.3 1 0 0 1 1 1 1 PCI domain His_kinase PF06580.8 CCD22272.1 - 0.12 12.2 0.7 2.2 8.2 0.0 2.2 1 1 1 2 2 2 0 Histidine kinase CybS PF05328.7 CCD22273.1 - 7.7e-46 155.0 0.1 9.3e-46 154.7 0.0 1.1 1 0 0 1 1 1 1 CybS UQ_con PF00179.21 CCD22274.1 - 4.1e-43 146.1 0.0 5.4e-43 145.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 CCD22274.1 - 1.1e-27 95.3 1.6 1.9e-27 94.6 1.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 CCD22274.1 - 0.0012 18.5 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Ada3 PF10198.4 CCD22275.1 - 5e-44 149.2 2.9 5e-44 149.2 2.0 4.0 5 1 0 5 5 5 1 Histone acetyltransferases subunit 3 MRP-S28 PF10213.4 CCD22276.1 - 5.3e-47 159.0 8.9 2.1e-46 157.1 2.7 2.3 2 0 0 2 2 2 2 Mitochondrial ribosomal subunit protein VPS11_C PF12451.3 CCD22276.1 - 0.22 11.4 2.7 3.1 7.7 0.2 3.0 2 1 1 3 3 3 0 Vacuolar protein sorting protein 11 C terminal HMG_box PF00505.14 CCD22277.1 - 2.6e-11 43.6 4.0 2.6e-11 43.6 2.8 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCD22277.1 - 2.3e-08 34.2 2.5 2.3e-08 34.2 1.7 1.9 2 0 0 2 2 2 1 HMG-box domain DUF3086 PF11285.3 CCD22277.1 - 0.012 14.4 0.9 0.016 14.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3086) tRNA-synt_1g PF09334.6 CCD22277.1 - 0.062 11.9 2.9 0.098 11.2 2.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) Mit_KHE1 PF10173.4 CCD22277.1 - 9 6.1 7.9 1.6 8.5 1.0 2.3 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related IPK PF03770.11 CCD22278.1 - 1.2e-53 181.6 3.1 1.7e-53 181.1 2.2 1.2 1 0 0 1 1 1 1 Inositol polyphosphate kinase YL1 PF05764.8 CCD22278.1 - 0.12 11.9 1.3 0.19 11.3 0.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein PI3K_1B_p101 PF10486.4 CCD22278.1 - 0.15 9.6 2.0 0.22 9.0 1.4 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit PBP1_TM PF14812.1 CCD22278.1 - 1.5 9.2 10.9 0.15 12.3 4.0 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GTP_EFTU PF00009.22 CCD22279.1 - 1.1e-46 158.6 0.0 1.1e-46 158.6 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCD22279.1 - 1.4e-24 86.1 1.1 1.4e-24 86.1 0.8 2.4 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCD22279.1 - 3.2e-08 33.5 0.9 8.7e-08 32.1 0.6 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCD22279.1 - 0.0014 18.5 0.0 0.0014 18.5 0.0 2.5 2 2 0 2 2 2 1 50S ribosome-binding GTPase HSP20 PF00011.16 CCD22280.1 - 1e-11 44.5 0.1 1e-11 44.5 0.1 2.4 3 1 1 4 4 4 1 Hsp20/alpha crystallin family Sec7 PF01369.15 CCD22281.1 - 2.6e-66 222.9 0.0 1.9e-65 220.0 0.0 2.6 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 CCD22281.1 - 7.8e-51 171.8 2.0 7.8e-51 171.8 1.4 3.3 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CCD22281.1 - 7.8e-28 95.8 2.0 7.8e-28 95.8 1.4 4.7 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) AMP-binding PF00501.23 CCD22282.1 - 9.2e-90 300.9 0.1 1.1e-89 300.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCD22282.1 - 8.9e-18 65.0 0.2 2.3e-17 63.7 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TIP41 PF04176.8 CCD22283.1 - 1.2e-64 216.9 8.1 1.9e-64 216.2 5.6 1.3 1 0 0 1 1 1 1 TIP41-like family Evr1_Alr PF04777.8 CCD22284.1 - 1.3e-07 31.4 0.2 9.3e-07 28.6 0.1 2.3 1 1 0 1 1 1 1 Erv1 / Alr family V-ATPase_H_N PF03224.9 CCD22286.1 - 2.2e-55 187.9 14.2 2.2e-55 187.9 9.8 1.7 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CCD22286.1 - 7.5e-41 138.7 0.2 7.5e-41 138.7 0.2 3.2 3 1 1 4 4 4 2 V-ATPase subunit H TMF_TATA_bd PF12325.3 CCD22286.1 - 0.1 12.3 12.6 0.08 12.6 0.4 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Gln-synt_C PF00120.19 CCD22287.1 - 7.7e-67 225.1 0.0 9.3e-67 224.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CCD22287.1 - 2.7e-20 71.7 0.0 4.5e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Actin PF00022.14 CCD22288.1 - 5.6e-53 179.7 0.2 8.2e-52 175.9 0.2 2.2 1 1 0 1 1 1 1 Actin tRNA-synt_His PF13393.1 CCD22289.1 - 8.7e-38 130.1 0.0 1.1e-32 113.3 0.0 2.0 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CCD22289.1 - 2.6e-19 69.4 0.0 1.8e-18 66.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCD22289.1 - 3.3e-11 42.9 0.0 6.8e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 CCD22289.1 - 0.0037 16.1 0.2 0.044 12.5 0.1 2.3 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CCD22289.1 - 0.009 15.2 0.0 0.019 14.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) DUF3149 PF11346.3 CCD22289.1 - 0.019 14.4 1.5 0.045 13.3 1.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) HGTP_anticodon2 PF12745.2 CCD22289.1 - 0.03 13.4 1.2 0.044 12.9 0.0 1.7 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs zf-HC5HC2H_2 PF13832.1 CCD22290.1 - 1.1e-30 105.8 5.1 1.1e-30 105.8 3.5 2.2 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CCD22290.1 - 8.6e-28 96.3 3.6 8.6e-28 96.3 2.5 2.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 CCD22290.1 - 1.1e-13 50.1 3.0 1.1e-13 50.1 2.1 3.0 3 0 0 3 3 3 1 PHD-finger PHD PF00628.24 CCD22290.1 - 1.4e-08 34.3 4.2 1.4e-08 34.3 2.9 2.6 2 0 0 2 2 2 1 PHD-finger EPL1 PF10513.4 CCD22290.1 - 2.3e-07 31.1 0.2 2.3e-07 31.1 0.2 2.1 2 0 0 2 2 2 1 Enhancer of polycomb-like FXR1P_C PF12235.3 CCD22290.1 - 0.0086 16.1 5.4 0.019 15.0 3.7 1.5 1 0 0 1 1 1 1 Fragile X-related 1 protein C terminal C1_1 PF00130.17 CCD22290.1 - 1.5 8.5 20.6 0.23 11.2 0.9 2.9 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 CCD22290.1 - 1.9 8.3 15.6 2 8.1 1.7 2.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 CCD22290.1 - 2.2 8.3 27.3 1 9.4 5.6 2.8 3 0 0 3 3 3 0 RING-like domain zf-PHD-like PF15446.1 CCD22290.1 - 2.7 7.2 11.6 0.037 13.3 1.6 2.2 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain Arrestin_N PF00339.24 CCD22291.1 - 0.00027 20.7 3.6 0.0015 18.3 0.1 3.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain AA_permease PF00324.16 CCD22292.1 - 3.7e-114 381.7 40.7 4.5e-114 381.4 28.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD22292.1 - 9.7e-36 123.2 46.4 1.3e-35 122.7 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease Adaptin_N PF01602.15 CCD22293.1 - 6e-85 285.5 25.4 8.3e-85 285.0 17.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CCD22293.1 - 3.5e-05 24.0 0.1 0.0001 22.5 0.1 1.9 1 0 0 1 1 1 1 Adaptin C-terminal domain Vac14_Fab1_bd PF12755.2 CCD22293.1 - 0.00043 20.6 2.8 0.018 15.4 0.1 3.6 3 1 1 4 4 4 1 Vacuolar 14 Fab1-binding region TB2_DP1_HVA22 PF03134.14 CCD22294.1 - 1.2e-30 105.0 2.7 1.7e-30 104.5 1.8 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF4512 PF14975.1 CCD22294.1 - 0.1 13.3 0.0 0.26 12.1 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) Glyco_hydro_65m PF03632.10 CCD22295.1 - 7e-97 324.4 3.3 7e-97 324.4 2.3 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 CCD22295.1 - 1e-42 146.2 0.1 2e-42 145.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 CCD22295.1 - 5.8e-10 39.1 0.5 1.6e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain Peptidase_M56 PF05569.6 CCD22295.1 - 0.066 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 Cyclin_N PF00134.18 CCD22296.1 - 3.9e-11 42.6 0.6 8.5e-11 41.5 0.4 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 CCD22296.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Peptidase_M41 PF01434.13 CCD22297.1 - 1.3e-61 207.7 0.3 2.8e-61 206.6 0.2 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CCD22297.1 - 5.5e-41 139.8 0.0 1.7e-40 138.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCD22297.1 - 6.2e-06 26.3 0.1 0.0059 16.7 0.1 2.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCD22297.1 - 1.5e-05 25.0 0.0 6e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 CCD22297.1 - 0.00048 18.9 0.0 0.00083 18.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 CCD22297.1 - 0.00054 20.7 0.0 0.0015 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCD22297.1 - 0.00064 19.1 0.9 0.055 12.8 0.4 2.4 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 CCD22297.1 - 0.00076 19.3 0.0 0.05 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCD22297.1 - 0.0013 17.8 0.0 0.0039 16.2 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CCD22297.1 - 0.0021 17.7 0.1 0.0091 15.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCD22297.1 - 0.0023 17.6 2.3 0.0073 16.0 1.6 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CCD22297.1 - 0.0043 16.4 0.0 0.0095 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCD22297.1 - 0.026 13.6 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CCD22297.1 - 0.026 14.8 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCD22297.1 - 0.029 14.2 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 CCD22297.1 - 0.041 13.0 0.2 0.093 11.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CCD22297.1 - 0.066 12.3 0.0 0.42 9.7 0.0 2.1 2 0 0 2 2 2 0 KaiC Peptidase_M50B PF13398.1 CCD22297.1 - 0.093 12.0 0.2 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 Peptidase M50B-like AAA_28 PF13521.1 CCD22297.1 - 0.096 12.6 0.3 0.29 11.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain TFIIF_alpha PF05793.7 CCD22297.1 - 0.25 9.6 4.3 0.38 9.0 3.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TPP_enzyme_N PF02776.13 CCD22298.1 - 4.1e-34 117.5 0.0 6e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCD22298.1 - 4.3e-34 117.2 0.0 1.6e-33 115.3 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCD22298.1 - 2.7e-15 56.2 0.0 4.9e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 CCD22298.1 - 0.058 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit DXP_synthase_N PF13292.1 CCD22298.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.4 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 CCD22298.1 - 0.12 11.1 0.1 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component ArfGap PF01412.13 CCD22299.1 - 4e-33 113.6 0.9 4e-33 113.6 0.6 3.1 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf PAT1 PF09770.4 CCD22300.1 - 0.17 10.0 13.9 0.23 9.6 9.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dioxygenase_N PF04444.9 CCD22301.1 - 0.14 12.1 0.2 0.43 10.6 0.0 1.9 2 0 0 2 2 2 0 Catechol dioxygenase N terminus Motile_Sperm PF00635.21 CCD22302.1 - 1.8e-25 88.7 0.2 1.8e-25 88.7 0.1 2.4 2 1 0 2 2 2 1 MSP (Major sperm protein) domain Endomucin PF07010.7 CCD22302.1 - 0.022 14.1 14.7 0.0073 15.6 8.1 1.7 2 0 0 2 2 2 0 Endomucin FLO_LFY PF01698.11 CCD22302.1 - 0.18 10.6 6.3 0.26 10.0 4.4 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF3439 PF11921.3 CCD22302.1 - 0.2 11.4 5.9 0.43 10.3 4.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 CCD22302.1 - 0.33 8.8 7.0 0.45 8.4 4.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mitofilin PF09731.4 CCD22302.1 - 2 6.9 21.9 2.5 6.6 15.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein IER PF05760.7 CCD22302.1 - 3.4 7.5 11.3 4.8 7.0 7.9 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Otopetrin PF03189.8 CCD22302.1 - 5.1 5.9 5.8 7.6 5.4 4.0 1.3 1 0 0 1 1 1 0 Otopetrin A2M_N PF01835.14 CCD22302.1 - 6 7.1 0.0 6 7.1 0.0 3.1 3 1 1 4 4 4 0 MG2 domain Peptidase_M24 PF00557.19 CCD22303.1 - 1e-51 175.4 0.0 1.4e-51 175.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Protocadherin PF08374.6 CCD22303.1 - 0.038 13.6 0.6 0.062 12.9 0.4 1.3 1 0 0 1 1 1 0 Protocadherin Ribosomal_S21 PF01165.15 CCD22304.1 - 2.6e-08 33.1 0.5 5.1e-08 32.2 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S21 SH3_1 PF00018.23 CCD22305.1 - 2.1e-12 46.2 0.2 4e-12 45.3 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCD22305.1 - 1.4e-11 43.7 0.1 3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCD22305.1 - 8.3e-09 34.8 0.0 2.1e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain DUF4234 PF14018.1 CCD22305.1 - 0.97 9.2 10.5 7.8 6.3 3.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) Ribosomal_L14 PF00238.14 CCD22306.1 - 5.1e-32 110.1 0.0 5.7e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e zf-RING_2 PF13639.1 CCD22307.1 - 9.8e-10 38.1 11.4 1.6e-09 37.3 7.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCD22307.1 - 3e-09 36.3 9.9 5.3e-09 35.5 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCD22307.1 - 3.1e-09 36.3 9.1 4.6e-09 35.8 6.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD22307.1 - 1.8e-07 31.0 10.9 3e-07 30.3 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCD22307.1 - 4e-06 26.4 6.8 1.1e-05 24.9 4.7 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CCD22307.1 - 1.2e-05 24.9 9.9 2e-05 24.2 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCD22307.1 - 0.0018 18.1 10.6 0.0034 17.2 7.4 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FYVE_2 PF02318.11 CCD22307.1 - 0.0046 16.8 2.2 0.0085 15.9 1.5 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-Apc11 PF12861.2 CCD22307.1 - 0.0065 16.2 4.9 0.011 15.5 3.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Phage_T7_tail PF03906.9 CCD22307.1 - 0.02 14.5 0.6 0.02 14.5 0.4 2.0 2 0 0 2 2 2 0 Phage T7 tail fibre protein Saw1 PF11561.3 CCD22307.1 - 0.025 13.9 1.1 0.038 13.3 0.7 1.5 1 1 0 1 1 1 0 Single strand annealing-weakened 1 zf-RING_4 PF14570.1 CCD22307.1 - 0.029 13.9 7.5 0.066 12.8 5.2 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CCD22307.1 - 0.17 11.9 5.6 0.35 10.9 3.9 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-MIZ PF02891.15 CCD22307.1 - 8.7 5.9 10.8 56 3.3 7.3 2.1 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger SH3_1 PF00018.23 CCD22308.1 - 1.4e-12 46.7 0.9 2.3e-12 46.1 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SAM_2 PF07647.12 CCD22308.1 - 2.1e-11 43.4 0.0 7.7e-11 41.6 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 CCD22308.1 - 5.9e-09 35.3 0.2 1.1e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH PF00169.24 CCD22308.1 - 9.5e-09 35.4 0.0 4.7e-08 33.1 0.0 2.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 CCD22308.1 - 3.1e-07 30.6 0.7 1.4e-06 28.5 0.0 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_2 PF07653.12 CCD22308.1 - 0.00095 18.6 0.0 0.0022 17.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.25 CCD22308.1 - 0.0011 19.0 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 CCD22308.1 - 0.0056 16.7 0.0 6.8 6.8 0.0 3.0 2 0 0 2 2 2 2 Pleckstrin homology domain LURAP PF14854.1 CCD22308.1 - 0.0069 16.0 0.0 0.029 14.0 0.0 2.1 1 0 0 1 1 1 1 Leucine rich adaptor protein Agenet PF05641.7 CCD22308.1 - 0.064 13.4 0.1 0.29 11.3 0.0 2.2 2 0 0 2 2 2 0 Agenet domain EMP70 PF02990.11 CCD22309.1 - 6.5e-138 460.4 19.6 1.3e-137 459.4 13.6 1.5 1 1 0 1 1 1 1 Endomembrane protein 70 LSM PF01423.17 CCD22310.1 - 2.8e-15 55.6 0.1 5.1e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCD22310.1 - 3.7e-05 23.5 0.0 8.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1183 PF06682.7 CCD22310.1 - 0.065 12.8 8.6 0.071 12.6 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Ank_2 PF12796.2 CCD22311.1 - 3.9e-08 33.5 1.1 0.0012 19.1 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCD22311.1 - 2.9e-07 29.9 2.1 0.00041 20.0 0.2 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CCD22311.1 - 6.7e-07 29.3 2.7 0.00069 19.7 0.2 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) KilA-N PF04383.8 CCD22311.1 - 4.9e-06 26.1 0.1 3.3e-05 23.4 0.1 2.5 1 1 0 1 1 1 1 KilA-N domain Ank_3 PF13606.1 CCD22311.1 - 3.1e-05 23.7 2.1 0.064 13.5 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CCD22311.1 - 0.00089 19.7 4.7 1.6 9.3 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) HEAT_EZ PF13513.1 CCD22312.1 - 6.3e-18 64.7 1.6 0.014 15.9 0.0 9.4 9 0 0 9 9 9 4 HEAT-like repeat IBN_N PF03810.14 CCD22312.1 - 3.9e-15 55.5 5.6 1.7e-09 37.4 0.0 5.2 4 0 0 4 4 4 3 Importin-beta N-terminal domain HEAT PF02985.17 CCD22312.1 - 1.4e-14 52.7 2.7 0.015 15.3 0.0 8.9 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.1 CCD22312.1 - 2.4e-13 50.1 3.9 0.05 13.8 0.9 7.2 5 2 2 7 7 7 5 HEAT repeats G-alpha PF00503.15 CCD22312.1 - 0.0087 14.7 0.5 0.022 13.4 0.0 2.0 2 0 0 2 2 2 1 G-protein alpha subunit RICTOR_V PF14668.1 CCD22312.1 - 0.098 12.5 0.3 3 7.8 0.0 3.4 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 RPAP1_N PF08621.5 CCD22312.1 - 0.99 9.0 7.9 2.1 7.9 0.6 3.0 2 0 0 2 2 2 0 RPAP1-like, N-terminal LisH PF08513.6 CCD22313.1 - 0.00033 20.3 0.2 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 LisH WD40 PF00400.27 CCD22314.1 - 1e-26 91.7 5.2 5.3e-06 26.0 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 CCD22314.1 - 0.003 15.7 0.5 0.049 11.7 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 MAM1 PF10434.4 CCD22315.1 - 9.9e-38 129.8 14.4 9.9e-38 129.8 10.0 1.6 2 0 0 2 2 2 1 Monopolin complex protein MAM1 Atg8 PF02991.11 CCD22316.1 - 1.5e-48 163.0 0.1 1.7e-48 162.8 0.0 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CCD22316.1 - 3.4e-07 30.3 0.0 4.3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Inos-1-P_synth PF01658.12 CCD22317.1 - 0.018 14.8 0.0 0.43 10.4 0.0 2.2 1 1 0 1 1 1 0 Myo-inositol-1-phosphate synthase HSP70 PF00012.15 CCD22318.1 - 9.3e-270 895.7 8.9 1.1e-269 895.5 6.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCD22318.1 - 3.1e-17 62.1 0.1 4.1e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CCD22318.1 - 0.00081 19.0 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 CCD22318.1 - 0.17 10.9 3.4 0.26 10.3 0.0 2.8 3 1 0 4 4 4 0 Hydantoinase/oxoprolinase AAR2 PF05282.6 CCD22319.1 - 1.4e-55 188.6 8.1 1.7e-55 188.4 5.6 1.0 1 0 0 1 1 1 1 AAR2 protein Ribosomal_S8e PF01201.17 CCD22320.1 - 5.8e-51 172.0 2.1 6.7e-51 171.8 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e zf-CSL PF05207.8 CCD22321.1 - 2.1e-22 78.3 0.5 2.9e-22 77.9 0.3 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 CCD22321.1 - 0.045 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Zinc ribbon domain ADH_zinc_N_2 PF13602.1 CCD22322.1 - 5.7e-12 46.6 0.0 1e-11 45.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCD22322.1 - 4.3e-07 29.6 0.2 1e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SplA PF11132.3 CCD22322.1 - 0.0069 16.1 0.1 0.032 13.9 0.1 2.0 2 0 0 2 2 2 1 Transcriptional regulator protein (SplA) UQ_con PF00179.21 CCD22323.1 - 2.1e-28 98.4 0.0 3e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCD22323.1 - 0.0065 16.3 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 CCD22323.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B Pribosyltran_N PF13793.1 CCD22324.1 - 3e-44 149.4 0.2 3.5e-42 142.7 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CCD22324.1 - 1.1e-35 123.0 0.9 2e-29 102.6 0.3 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CCD22324.1 - 2e-12 46.9 0.6 6e-12 45.3 0.2 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCD22324.1 - 0.0023 17.1 0.1 0.0035 16.5 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UCH PF00443.24 CCD22325.1 - 1.6e-67 227.4 39.9 1.6e-67 227.4 27.6 3.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCD22325.1 - 1.1e-22 80.8 0.7 1.1e-22 80.8 0.5 4.7 3 1 1 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase Rad51 PF08423.6 CCD22326.1 - 7.4e-136 451.0 0.0 9.3e-136 450.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CCD22326.1 - 9.2e-14 51.2 0.0 1.4e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 CCD22326.1 - 5e-12 45.7 0.4 1.3e-11 44.4 0.3 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain RecA PF00154.16 CCD22326.1 - 2e-11 43.5 0.0 2.8e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CCD22326.1 - 3.8e-06 26.1 0.0 7.4e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 CCD22326.1 - 0.044 12.6 0.0 0.09 11.6 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_22 PF13401.1 CCD22326.1 - 0.046 13.8 0.0 0.096 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Proteasome PF00227.21 CCD22327.1 - 3e-41 140.8 0.0 3.6e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TraS PF10624.4 CCD22328.1 - 0.023 14.2 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS DUF3899 PF13038.1 CCD22328.1 - 0.032 14.4 0.2 0.082 13.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) RICTOR_N PF14664.1 CCD22329.1 - 7.4e-94 314.3 13.4 4.2e-93 311.8 9.3 2.1 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 CCD22329.1 - 2.7e-76 255.5 2.2 2.7e-76 255.5 1.6 5.9 6 1 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 CCD22329.1 - 5.9e-30 103.5 0.8 5.9e-30 103.5 0.6 2.5 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 CCD22329.1 - 6.9e-29 99.5 0.6 1.3e-27 95.4 0.3 3.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 RasGEF_N PF00618.15 CCD22329.1 - 0.016 15.3 0.7 0.016 15.3 0.5 3.9 4 0 0 4 4 4 0 RasGEF N-terminal motif PFEMP PF03011.10 CCD22329.1 - 0.52 10.6 13.7 4.1 7.7 0.0 3.7 3 0 0 3 3 3 0 PFEMP DBL domain DivIC PF04977.10 CCD22329.1 - 0.91 9.0 11.0 2 7.9 1.4 2.9 1 1 1 2 2 2 0 Septum formation initiator AKNA PF12443.3 CCD22329.1 - 3.3 7.7 8.9 3.7 7.6 0.6 3.2 2 1 1 3 3 3 0 AT-hook-containing transcription factor Pox_polyA_pol_N PF12630.2 CCD22330.1 - 0.066 13.3 0.1 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Meth_synt_2 PF01717.13 CCD22331.1 - 1.7e-140 467.6 0.0 1.6e-136 454.5 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CCD22331.1 - 7.1e-127 422.9 0.8 5.6e-115 383.8 0.0 3.5 4 0 0 4 4 4 3 Cobalamin-independent synthase, N-terminal domain Chorismate_bind PF00425.13 CCD22332.1 - 5.1e-86 288.1 0.0 8.4e-86 287.4 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 CCD22332.1 - 9.4e-30 103.4 0.1 1.9e-27 96.0 0.0 3.3 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region POR PF01558.13 CCD22332.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase PP2C PF00481.16 CCD22333.1 - 1.1e-82 277.3 0.1 1.8e-82 276.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Myb_DNA-bind_6 PF13921.1 CCD22335.1 - 2.3e-11 43.5 5.0 1.5e-09 37.7 0.3 3.2 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCD22335.1 - 1.1e-09 38.1 1.2 2.1e-07 30.8 0.2 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Rap1_C PF11626.3 CCD22335.1 - 0.042 13.7 0.1 2.2 8.1 0.0 2.6 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain RRM_6 PF14259.1 CCD22336.1 - 2.3e-08 33.8 0.0 4.9e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCD22336.1 - 2.3e-07 30.3 0.0 5.7e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD22336.1 - 0.00075 19.2 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec61_beta PF03911.11 CCD22337.1 - 1.1e-14 53.8 2.2 1.4e-14 53.5 1.5 1.1 1 0 0 1 1 1 1 Sec61beta family tRNA-synt_2b PF00587.20 CCD22338.1 - 6.4e-31 107.2 0.0 1.2e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PALP PF00291.20 CCD22339.1 - 1.2e-72 244.7 0.3 1.5e-72 244.4 0.2 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 CCD22339.1 - 1.4e-41 139.9 0.0 1.2e-26 92.0 0.0 2.7 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase CYTL1 PF15153.1 CCD22340.1 - 0.0034 17.0 1.1 0.0065 16.1 0.0 2.0 2 0 0 2 2 2 1 Cytokine-like protein 1 FAD-oxidase_C PF02913.14 CCD22341.1 - 2.2e-55 187.6 0.0 3.1e-55 187.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCD22341.1 - 1.6e-36 124.8 0.0 5.6e-36 123.0 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain DUF3602 PF12223.3 CCD22343.1 - 5.9e-16 58.6 25.0 2.9e-12 46.8 0.2 4.0 3 1 1 4 4 4 3 Protein of unknown function (DUF3602) RtxA PF07634.6 CCD22343.1 - 1 9.7 5.8 2.2 8.7 0.0 3.5 3 0 0 3 3 3 0 RtxA repeat Glu_synthase PF01645.12 CCD22344.1 - 1.2e-154 514.6 0.0 2e-154 514.0 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 CCD22344.1 - 6.2e-137 456.1 0.0 2.2e-136 454.3 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 CCD22344.1 - 1.9e-113 378.5 0.0 4.7e-113 377.2 0.0 1.7 2 0 0 2 2 1 1 Glutamate synthase central domain GXGXG PF01493.14 CCD22344.1 - 3e-58 196.1 2.7 6.2e-58 195.1 1.8 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 CCD22344.1 - 1.2e-23 82.8 0.1 2.3e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 CCD22344.1 - 1.7e-16 60.7 0.0 4.5e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCD22344.1 - 1.9e-10 41.1 0.1 3.8e-05 23.8 0.0 2.6 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCD22344.1 - 1.5e-08 34.5 0.0 3.9e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCD22344.1 - 1.5e-08 34.9 0.8 7.5e-06 26.2 0.0 3.4 3 1 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCD22344.1 - 4.6e-06 25.7 0.2 0.00012 21.1 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CCD22344.1 - 2.3e-05 23.0 0.2 2.3e-05 23.0 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.19 CCD22344.1 - 4.6e-05 22.6 0.0 8.9e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 CCD22344.1 - 0.0002 20.3 0.0 0.00038 19.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 CCD22344.1 - 0.00062 19.9 0.1 0.49 10.6 0.0 2.9 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 CCD22344.1 - 0.0021 17.8 0.0 0.0052 16.5 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 CCD22344.1 - 0.0027 16.8 0.0 0.0051 15.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GATase_6 PF13522.1 CCD22344.1 - 0.0083 16.0 0.0 0.035 14.0 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain Thi4 PF01946.12 CCD22344.1 - 0.01 14.9 0.1 0.032 13.3 0.0 1.8 2 0 0 2 2 2 0 Thi4 family GIDA PF01134.17 CCD22344.1 - 0.013 14.3 0.3 0.07 11.9 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A F420_oxidored PF03807.12 CCD22344.1 - 0.015 15.6 0.1 0.33 11.4 0.0 3.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FMO-like PF00743.14 CCD22344.1 - 0.017 13.3 0.4 1.6 6.8 0.0 2.9 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_2 PF03446.10 CCD22344.1 - 0.018 14.8 0.1 0.07 12.9 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 CCD22344.1 - 0.031 14.1 0.5 14 5.5 0.0 3.1 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Shikimate_DH PF01488.15 CCD22344.1 - 0.035 14.2 0.8 8.9 6.4 0.0 3.0 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 CCD22344.1 - 0.062 12.6 0.9 0.22 10.8 0.0 2.3 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_3 PF01494.14 CCD22344.1 - 0.065 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 CCD22344.1 - 0.082 12.0 0.0 3.8 6.6 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CCD22344.1 - 0.084 12.4 0.0 2.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 CCD22344.1 - 0.24 11.0 1.3 0.43 10.2 0.0 2.2 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF4279 PF14106.1 CCD22345.1 - 0.12 12.2 0.4 0.24 11.2 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) Nop PF01798.13 CCD22346.1 - 2e-60 202.4 0.1 5e-60 201.1 0.1 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CCD22346.1 - 8.1e-27 92.7 0.1 1.8e-26 91.6 0.1 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CCD22346.1 - 1.2e-24 86.2 0.4 3.9e-24 84.5 0.3 2.0 1 0 0 1 1 1 1 NOP5NT (NUC127) domain PcfK PF14058.1 CCD22346.1 - 0.02 15.0 18.7 0.035 14.2 13.0 1.3 1 0 0 1 1 1 0 PcfK-like protein CDC45 PF02724.9 CCD22346.1 - 0.13 10.2 18.7 0.17 9.8 13.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 CCD22346.1 - 0.45 10.2 7.9 0.72 9.6 5.5 1.4 1 0 0 1 1 1 0 DDHD domain RNA_polI_A34 PF08208.6 CCD22346.1 - 1.3 8.6 33.0 2.2 7.9 22.9 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 CCD22346.1 - 2 8.3 14.1 3.2 7.6 9.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CCD22346.1 - 2.2 8.1 15.6 4.4 7.1 10.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MIP-T3 PF10243.4 CCD22346.1 - 3.8 5.8 31.2 5.1 5.4 21.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Herpes_DNAp_acc PF04929.7 CCD22346.1 - 4.4 6.1 14.2 6.1 5.6 9.9 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor ADH_N PF08240.7 CCD22347.1 - 1e-23 83.1 2.1 1e-23 83.1 1.5 2.0 1 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCD22347.1 - 8.3e-21 73.8 0.2 1.4e-20 73.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCD22347.1 - 0.0047 16.0 0.1 0.0078 15.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CCD22347.1 - 0.029 13.7 0.2 0.064 12.6 0.1 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 CCD22347.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 CCD22347.1 - 0.053 13.7 0.1 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 CCD22347.1 - 0.069 12.7 2.7 0.12 11.9 1.9 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase HycI PF01750.13 CCD22347.1 - 0.09 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Hydrogenase maturation protease zf-RanBP PF00641.13 CCD22348.1 - 1e-21 75.6 11.6 1.1e-10 40.3 1.8 2.6 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 CCD22348.1 - 3.7e-08 32.8 0.3 9.7e-05 21.9 0.0 3.4 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 CCD22348.1 - 0.011 15.5 9.3 0.72 9.7 1.2 2.5 2 0 0 2 2 2 0 Double zinc ribbon RRM_6 PF14259.1 CCD22348.1 - 0.02 14.8 0.0 0.16 11.9 0.0 2.5 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rubredoxin PF00301.15 CCD22348.1 - 0.035 13.9 2.7 4.5 7.2 0.2 2.6 2 0 0 2 2 2 0 Rubredoxin zf-MIZ PF02891.15 CCD22348.1 - 0.087 12.3 2.3 6.3 6.4 0.1 2.5 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger AAA_18 PF13238.1 CCD22349.1 - 3.5e-30 104.9 0.1 3.5e-30 104.9 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCD22349.1 - 3.5e-14 53.6 0.5 7.3e-14 52.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CCD22349.1 - 1.6e-05 24.3 0.1 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 CCD22349.1 - 0.00017 21.4 0.0 0.081 12.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 CCD22349.1 - 0.00024 21.2 0.0 0.00045 20.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCD22349.1 - 0.0003 20.0 0.0 0.0023 17.2 0.0 2.1 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 CCD22349.1 - 0.0012 18.8 0.1 0.0048 16.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain ADK PF00406.17 CCD22349.1 - 0.0012 18.7 0.1 0.48 10.2 0.0 2.3 2 0 0 2 2 2 1 Adenylate kinase AAA_14 PF13173.1 CCD22349.1 - 0.0017 18.2 0.0 0.0044 16.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCD22349.1 - 0.0018 18.4 0.1 0.0066 16.6 0.0 1.9 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.1 CCD22349.1 - 0.0021 18.0 0.1 0.0025 17.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 CCD22349.1 - 0.0036 16.8 0.0 0.0091 15.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CCD22349.1 - 0.0037 16.7 0.0 0.0076 15.7 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.1 CCD22349.1 - 0.0066 16.1 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 CCD22349.1 - 0.0074 16.0 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 CCD22349.1 - 0.0099 15.3 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain ABC_tran PF00005.22 CCD22349.1 - 0.016 15.5 0.1 0.23 11.7 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Mg_chelatase PF01078.16 CCD22349.1 - 0.019 14.1 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CCD22349.1 - 0.022 13.8 0.0 0.069 12.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 CCD22349.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 NTPase Cytidylate_kin2 PF13189.1 CCD22349.1 - 0.04 13.8 0.5 0.35 10.7 0.1 2.6 1 1 1 2 2 2 0 Cytidylate kinase-like family T2SE PF00437.15 CCD22349.1 - 0.04 12.8 0.1 0.11 11.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ArgK PF03308.11 CCD22349.1 - 0.045 12.5 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 ArgK protein MobB PF03205.9 CCD22349.1 - 0.046 13.4 0.0 0.081 12.6 0.0 1.6 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 CCD22349.1 - 0.056 13.6 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 CCD22349.1 - 0.06 13.1 1.2 0.82 9.4 0.0 2.6 1 1 2 3 3 3 0 Domain of unknown function DUF87 KaiC PF06745.8 CCD22349.1 - 0.07 12.2 0.1 1.7 7.6 0.0 2.1 2 0 0 2 2 2 0 KaiC APC_CDC26 PF10471.4 CCD22349.1 - 0.15 12.7 4.7 0.3 11.8 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF2407_C PF13373.1 CCD22349.1 - 8 6.3 10.1 18 5.2 7.0 1.6 1 1 0 1 1 1 0 DUF2407 C-terminal domain NOT2_3_5 PF04153.13 CCD22350.1 - 8.9e-34 116.2 2.2 1.1e-33 116.0 1.5 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Imm43 PF15602.1 CCD22350.1 - 0.038 13.9 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 2 0 Immunity protein 43 zf-Mss51 PF13824.1 CCD22351.1 - 5.4e-18 64.6 0.3 1.2e-17 63.4 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.6 CCD22351.1 - 0.0014 18.1 0.0 0.0033 16.9 0.0 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DNA_ligase_A_M PF01068.16 CCD22352.1 - 2.4e-60 203.3 0.5 3.7e-60 202.7 0.3 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CCD22352.1 - 1.6e-52 177.8 0.2 2.8e-52 177.1 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CCD22352.1 - 1.7e-26 92.4 0.0 6.2e-26 90.6 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 CCD22352.1 - 0.0099 15.5 0.5 1.7 8.3 0.1 2.7 2 0 0 2 2 2 2 DNA ligase OB-like domain CENP-X PF09415.5 CCD22353.1 - 4.9e-20 71.1 5.4 1.3e-19 69.7 3.8 1.7 1 1 0 1 1 1 1 CENP-S associating Centromere protein X TcdA_TcdB PF12919.2 CCD22353.1 - 0.059 11.8 0.5 0.07 11.6 0.3 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain IL15 PF02372.10 CCD22353.1 - 0.1 12.4 1.1 0.12 12.1 0.8 1.2 1 0 0 1 1 1 0 Interleukin 15 DEAD PF00270.24 CCD22354.1 - 1.4e-41 141.8 0.1 2.8e-41 140.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD22354.1 - 1.2e-25 89.1 0.2 3.2e-25 87.7 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.20 CCD22355.1 - 3.5e-65 219.7 1.5 6.4e-65 218.8 1.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22355.1 - 1.4e-38 132.4 0.3 2.1e-37 128.6 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD22355.1 - 1.5e-05 24.1 0.0 2.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCD22355.1 - 0.31 10.7 0.0 0.54 9.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 CCD22357.1 - 4.1e-12 45.4 6.7 0.00037 20.2 0.0 5.7 6 0 0 6 6 6 4 WD domain, G-beta repeat Cyclin_N PF00134.18 CCD22358.1 - 1.4e-39 134.5 0.1 3.8e-39 133.1 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCD22358.1 - 7.9e-30 103.2 0.9 6.3e-28 97.0 0.0 2.7 2 1 0 2 2 2 2 Cyclin, C-terminal domain MutS_V PF00488.16 CCD22359.1 - 3.3e-56 190.3 0.0 5.6e-56 189.5 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCD22359.1 - 4.2e-29 101.8 2.8 4.2e-29 101.8 1.9 2.3 3 1 0 3 3 3 1 MutS domain III MutS_IV PF05190.13 CCD22359.1 - 0.0067 16.5 0.7 0.051 13.7 0.2 2.7 2 1 0 2 2 2 1 MutS family domain IV NACHT PF05729.7 CCD22359.1 - 0.024 14.2 0.8 0.79 9.3 0.1 2.6 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 CCD22359.1 - 0.064 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 CCD22359.1 - 0.46 10.3 4.8 0.95 9.3 0.0 3.4 3 1 1 4 4 4 0 AAA domain Sas10 PF09368.5 CCD22360.1 - 3.6e-30 103.9 10.4 3.6e-30 103.9 7.2 2.2 2 0 0 2 2 2 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CCD22360.1 - 8.1e-10 38.7 0.4 4.9e-09 36.2 0.3 2.5 1 0 0 1 1 1 1 Sas10/Utp3/C1D family RNA_pol_Rpc4 PF05132.9 CCD22361.1 - 9.4e-29 100.0 0.6 9.4e-29 100.0 0.4 2.9 3 1 0 3 3 3 1 RNA polymerase III RPC4 APG9 PF04109.11 CCD22362.1 - 2.7e-159 529.9 13.5 3.6e-159 529.6 9.4 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 Macscav_rec PF03523.8 CCD22362.1 - 0.076 12.7 1.0 0.25 11.1 0.1 2.3 2 0 0 2 2 2 0 Macrophage scavenger receptor MFS_1 PF07690.11 CCD22363.1 - 4.3e-09 35.5 38.4 1.2e-07 30.7 26.0 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCD22363.1 - 1.3e-05 24.0 11.6 1.3e-05 24.0 8.1 3.8 4 2 0 4 4 4 1 Sugar (and other) transporter Nop14 PF04147.7 CCD22364.1 - 1.3e-209 698.2 87.9 1.4e-208 694.8 61.0 2.0 1 1 0 1 1 1 1 Nop14-like family PCI PF01399.22 CCD22365.1 - 2e-21 76.2 0.1 2e-21 76.2 0.1 2.7 2 1 0 2 2 2 1 PCI domain DUF2013 PF09431.5 CCD22366.1 - 9.7e-45 151.7 11.8 9.7e-45 151.7 8.2 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) Coatomer_WDAD PF04053.9 CCD22367.1 - 2.6e-133 445.0 3.9 4.1e-133 444.4 2.7 1.3 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CCD22367.1 - 7.3e-64 215.8 0.1 1.1e-63 215.3 0.0 1.3 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CCD22367.1 - 6.2e-58 190.7 13.2 4.1e-10 39.1 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CCD22367.1 - 6.6e-06 24.5 5.1 0.15 10.2 0.1 3.8 2 1 2 4 4 4 3 Nucleoporin Nup120/160 eIF2A PF08662.6 CCD22367.1 - 0.00031 20.4 0.3 2.6 7.7 0.0 4.0 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A TPR_2 PF07719.12 CCD22367.1 - 0.099 12.6 1.8 0.38 10.7 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCD22367.1 - 0.12 11.9 1.7 0.24 11.0 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat ApbA_C PF08546.6 CCD22368.1 - 2.2e-23 82.5 0.1 3.6e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CCD22368.1 - 6.6e-18 64.5 0.0 9.1e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.19 CCD22368.1 - 0.2 10.4 0.2 0.29 9.9 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Cpn60_TCP1 PF00118.19 CCD22369.1 - 3.4e-135 451.4 11.3 3.8e-135 451.2 7.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 CCD22369.1 - 0.0097 15.2 1.1 0.39 9.9 0.0 2.9 3 0 0 3 3 3 1 DeoC/LacD family aldolase BPL_N PF09825.4 CCD22370.1 - 6.9e-128 426.5 0.0 9.5e-128 426.0 0.0 1.2 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 CCD22370.1 - 6.5e-14 52.0 0.0 2.3e-13 50.2 0.0 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 CCD22370.1 - 2e-10 40.1 0.1 4.7e-10 39.0 0.1 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain RNA_pol_Rpb1_1 PF04997.7 CCD22371.1 - 2.1e-118 395.4 0.0 3.6e-118 394.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CCD22371.1 - 6.1e-108 360.2 0.1 1e-107 359.5 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CCD22371.1 - 1.1e-72 243.4 0.0 3.4e-72 241.7 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CCD22371.1 - 4.3e-65 218.9 0.5 1e-64 217.7 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 CCD22371.1 - 1.1e-45 155.1 0.0 2.9e-45 153.8 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 CCD22371.1 - 9.6e-45 151.6 3.6 2.1e-44 150.4 2.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 CCD22371.1 - 5.9e-35 119.2 0.1 1.7e-34 117.8 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 CCD22371.1 - 1.2e-14 52.9 276.1 0.054 13.6 9.0 14.9 2 1 15 21 21 21 18 RNA polymerase Rpb1 C-terminal repeat DUF4123 PF13503.1 CCD22371.1 - 0.055 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) Scm3 PF10384.4 CCD22372.1 - 2e-22 78.4 0.9 5.5e-22 77.0 0.7 1.8 1 0 0 1 1 1 1 Centromere protein Scm3 Sugar_tr PF00083.19 CCD22373.1 - 9.5e-125 416.6 31.2 1.1e-124 416.4 21.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD22373.1 - 6.6e-21 74.4 32.5 1.6e-15 56.6 6.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Arf PF00025.16 CCD22374.1 - 1.3e-77 258.9 0.0 1.6e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCD22374.1 - 2.6e-14 52.9 0.0 4.6e-14 52.1 0.0 1.4 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 CCD22374.1 - 1e-13 50.9 0.0 1.3e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCD22374.1 - 6.7e-11 41.5 0.5 7.4e-08 31.4 0.0 2.4 2 1 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCD22374.1 - 1.2e-10 40.8 0.0 1.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCD22374.1 - 2.2e-10 41.0 0.0 3.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCD22374.1 - 1.4e-05 25.0 0.0 2.1e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.17 CCD22374.1 - 0.0081 15.6 0.2 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain GTP_EFTU PF00009.22 CCD22374.1 - 0.011 15.2 0.0 0.053 12.9 0.0 1.8 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CCD22374.1 - 0.011 15.6 0.1 0.018 14.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CCD22374.1 - 0.037 13.6 0.5 3.9 7.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 CCD22374.1 - 0.053 13.8 0.1 0.098 12.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.13 CCD22374.1 - 0.054 12.5 0.1 0.081 11.9 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.14 CCD22374.1 - 0.13 11.6 0.1 8.2 5.8 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Ribosomal_L29 PF00831.18 CCD22375.1 - 1.2e-16 60.1 3.6 1.2e-16 60.1 2.5 2.3 2 1 0 2 2 2 1 Ribosomal L29 protein EcoEI_R_C PF08463.5 CCD22375.1 - 0.028 14.2 4.7 0.04 13.7 3.3 1.2 1 0 0 1 1 1 0 EcoEI R protein C-terminal MRP-L47 PF06984.8 CCD22375.1 - 0.11 12.3 3.1 0.18 11.7 0.7 2.3 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Hydantoinase_A PF01968.13 CCD22375.1 - 0.27 10.2 1.3 0.29 10.2 0.9 1.1 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase DUF3114 PF11311.3 CCD22375.1 - 0.32 10.3 4.5 0.36 10.1 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) DUF4600 PF15372.1 CCD22375.1 - 1.4 9.1 10.9 4.6 7.4 7.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Malate_DH PF12434.3 CCD22375.1 - 7.5 6.3 9.3 18 5.1 0.1 3.3 3 0 0 3 3 3 0 Malate dehydrogenase enzyme DUF883 PF05957.8 CCD22375.1 - 8.2 6.9 7.2 2.1 8.8 0.2 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Rho_GDI PF02115.12 CCD22376.1 - 2.2e-66 223.1 3.3 2.4e-66 222.9 2.3 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Cna_B PF05738.8 CCD22376.1 - 1.1 9.1 4.0 21 4.9 0.1 2.8 3 0 0 3 3 3 0 Cna protein B-type domain Metallophos PF00149.23 CCD22377.1 - 4.9e-41 140.3 0.5 6.6e-41 139.9 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ATP-synt_ab PF00006.20 CCD22378.1 - 7.9e-119 394.8 0.1 1.2e-118 394.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.11 CCD22378.1 - 1.2e-79 267.0 0.1 1.7e-79 266.5 0.1 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.9 CCD22378.1 - 8.2e-41 138.3 0.2 2.5e-37 127.2 0.1 2.5 2 0 0 2 2 2 2 Homing endonuclease ATP-synt_ab_C PF00306.22 CCD22378.1 - 4.5e-20 72.2 0.1 1.1e-19 70.9 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCD22378.1 - 1.4e-15 57.2 2.4 3.3e-15 56.0 1.6 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Hint PF01079.15 CCD22378.1 - 3e-05 23.3 0.0 7e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.1 CCD22378.1 - 4e-05 23.5 0.1 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 Hint domain Ribosomal_L41 PF05162.8 CCD22379.1 - 3.4e-09 36.1 25.8 3.6e-09 36.1 17.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 DUF1601 PF07671.6 CCD22379.1 - 0.25 10.9 1.7 0.28 10.8 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1601) MARVEL PF01284.18 CCD22380.1 - 0.036 13.8 2.9 0.068 12.9 2.0 1.5 1 0 0 1 1 1 0 Membrane-associating domain Cullin PF00888.17 CCD22381.1 - 2.7e-162 541.3 21.2 2.7e-162 541.3 14.7 1.3 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 CCD22381.1 - 1e-23 82.9 0.4 1e-23 82.9 0.3 3.7 4 0 0 4 4 4 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 CCD22381.1 - 0.008 16.2 0.1 0.1 12.7 0.0 3.0 3 0 0 3 3 3 1 Penicillinase repressor HMGL-like PF00682.14 CCD22382.1 - 2.4e-75 253.2 0.2 4.4e-75 252.4 0.1 1.4 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.15 CCD22382.1 - 0.068 11.6 0.0 7.1 5.0 0.0 2.5 2 0 0 2 2 2 0 Tryptophan synthase alpha chain ADP_PFK_GK PF04587.10 CCD22382.1 - 0.073 11.2 0.0 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region FliG_N PF14842.1 CCD22382.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 FliG N-terminal domain IATP PF04568.7 CCD22383.1 - 1.4e-18 66.7 0.2 1.5e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF342 PF03961.8 CCD22383.1 - 0.0095 14.4 0.2 0.0095 14.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF342) DASH_Dad2 PF08654.5 CCD22383.1 - 0.033 14.1 1.0 0.056 13.4 0.7 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad2 Phage_GP20 PF06810.6 CCD22383.1 - 0.041 13.3 3.5 0.048 13.1 2.4 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 Glutaredoxin2_C PF04399.8 CCD22383.1 - 0.19 11.3 1.5 0.24 10.9 1.0 1.2 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain ABC_tran_2 PF12848.2 CCD22383.1 - 0.42 10.4 6.0 0.57 10.0 4.1 1.3 1 0 0 1 1 1 0 ABC transporter FbpA PF05833.6 CCD22383.1 - 0.86 8.0 8.5 0.3 9.5 4.0 1.6 1 1 1 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) Cyclin_N PF00134.18 CCD22385.1 - 5.8e-14 51.7 0.0 1.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCD22385.1 - 6.8e-08 33.0 0.0 6.8e-08 33.0 0.0 2.3 2 1 0 2 2 2 1 Cyclin AAA PF00004.24 CCD22386.1 - 6e-99 327.4 0.0 2.4e-48 163.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CCD22386.1 - 7.8e-20 70.6 0.5 2.3e-19 69.1 0.3 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 CCD22386.1 - 2.4e-14 53.6 0.0 5.2e-07 29.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CCD22386.1 - 1.3e-13 50.6 0.1 1.7e-05 23.9 0.0 2.9 3 1 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CCD22386.1 - 6e-13 48.7 0.7 2.9e-06 27.0 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCD22386.1 - 7.3e-12 45.6 0.0 0.00052 20.0 0.0 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 CCD22386.1 - 2.6e-11 44.3 0.1 0.0008 20.2 0.0 3.7 4 1 0 4 4 2 2 AAA domain AAA_33 PF13671.1 CCD22386.1 - 2.9e-11 43.4 0.0 8.2e-06 25.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCD22386.1 - 1.2e-10 41.6 3.1 0.0011 19.1 0.1 4.4 3 2 0 3 3 2 2 AAA domain TIP49 PF06068.8 CCD22386.1 - 2.8e-09 36.2 0.1 0.0011 17.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 CCD22386.1 - 9.8e-09 35.1 0.0 0.0038 17.1 0.0 3.3 4 0 0 4 4 3 2 AAA domain IstB_IS21 PF01695.12 CCD22386.1 - 9.7e-08 31.6 0.0 0.0072 15.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 CCD22386.1 - 1.4e-07 31.0 7.5 0.029 13.7 0.3 4.5 2 2 2 4 4 4 2 AAA domain AAA_19 PF13245.1 CCD22386.1 - 1.7e-07 30.9 1.0 0.021 14.5 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 CCD22386.1 - 1.8e-07 31.3 0.0 0.0075 16.4 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.16 CCD22386.1 - 2.5e-07 30.0 0.4 0.021 13.9 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 CCD22386.1 - 2.6e-07 30.1 0.0 6.9e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.7 CCD22386.1 - 5.5e-07 28.8 0.2 0.013 14.6 0.0 3.0 3 1 0 3 3 3 2 Zeta toxin KaiC PF06745.8 CCD22386.1 - 1.5e-06 27.5 2.3 0.21 10.6 0.0 3.8 3 1 1 4 4 3 2 KaiC AAA_24 PF13479.1 CCD22386.1 - 1.7e-06 27.7 0.1 0.1 12.1 0.0 3.3 3 0 0 3 3 3 2 AAA domain ResIII PF04851.10 CCD22386.1 - 2e-06 27.7 0.7 0.0083 15.9 0.0 3.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 CCD22386.1 - 1e-05 25.1 0.1 0.13 11.7 0.0 3.6 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_18 PF13238.1 CCD22386.1 - 1e-05 25.8 0.0 0.13 12.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 CCD22386.1 - 1.1e-05 25.4 0.0 0.24 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 CCD22386.1 - 2.3e-05 23.7 0.5 0.11 11.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 CCD22386.1 - 3.2e-05 24.0 0.0 0.17 11.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CCD22386.1 - 3.2e-05 22.9 0.1 0.12 11.1 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 CCD22386.1 - 4e-05 23.4 0.2 0.44 10.1 0.1 4.2 2 2 2 4 4 4 1 Archaeal ATPase DUF815 PF05673.8 CCD22386.1 - 5.1e-05 22.3 0.0 0.08 11.8 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_11 PF13086.1 CCD22386.1 - 5.4e-05 22.8 0.0 0.31 10.5 0.0 2.6 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CCD22386.1 - 7.4e-05 23.0 0.1 0.12 12.6 0.0 3.8 3 1 0 3 3 2 1 ABC transporter Bac_DnaA PF00308.13 CCD22386.1 - 8e-05 22.3 0.0 0.19 11.3 0.0 3.2 3 0 0 3 3 3 1 Bacterial dnaA protein Vps4_C PF09336.5 CCD22386.1 - 9.1e-05 22.2 0.5 0.0015 18.3 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 CCD22386.1 - 0.00012 21.6 0.0 0.66 9.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCD22386.1 - 0.00013 21.6 0.2 1.6 8.3 0.0 3.7 4 0 0 4 4 3 1 NACHT domain DUF2075 PF09848.4 CCD22386.1 - 0.00044 19.3 0.0 0.67 8.8 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CCD22386.1 - 0.00078 19.0 0.0 1.7 8.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 CCD22386.1 - 0.0058 15.5 0.1 1.8 7.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain KAP_NTPase PF07693.9 CCD22386.1 - 0.0099 14.8 0.2 1.7 7.5 0.0 2.9 2 2 1 3 3 3 1 KAP family P-loop domain NTPase_1 PF03266.10 CCD22386.1 - 0.011 15.4 1.5 3.4 7.3 0.0 4.1 4 0 0 4 4 4 0 NTPase IPT PF01745.11 CCD22386.1 - 0.014 14.5 0.1 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 CCD22386.1 - 0.027 13.9 0.3 5.8 6.3 0.1 3.5 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) SKI PF01202.17 CCD22386.1 - 0.052 13.4 0.0 4.6 7.0 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 CCD22386.1 - 0.059 13.0 0.1 7 6.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 eIF-1a PF01176.14 CCD22386.1 - 0.061 12.7 0.3 1.3 8.5 0.0 2.9 2 1 1 3 3 3 0 Translation initiation factor 1A / IF-1 DEAD PF00270.24 CCD22386.1 - 0.1 12.1 0.3 25 4.3 0.0 3.5 3 1 0 4 4 4 0 DEAD/DEAH box helicase TEX19 PF15553.1 CCD22386.1 - 0.52 10.1 1.6 26 4.6 0.4 2.4 2 0 0 2 2 2 0 Testis-expressed protein 19 HIT PF01230.18 CCD22387.1 - 2.8e-25 88.6 0.1 3.5e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CCD22387.1 - 1.9e-08 34.5 0.8 2.6e-08 34.0 0.1 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CCD22387.1 - 0.018 14.6 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 Aldo_ket_red PF00248.16 CCD22388.1 - 1e-47 162.3 0.0 1.2e-47 162.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C8 PF03569.8 CCD22388.1 - 0.023 13.9 0.0 0.8 8.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase family C8 Pmp3 PF01679.12 CCD22389.1 - 5.2e-20 70.8 6.1 7e-20 70.4 4.2 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RVP_2 PF08284.6 CCD22389.1 - 0.14 12.1 0.0 0.2 11.5 0.0 1.4 1 1 0 1 1 1 0 Retroviral aspartyl protease zf-CCHC PF00098.18 CCD22390.1 - 3.8e-10 39.1 44.7 5.7e-05 22.8 1.5 5.1 5 1 0 5 5 5 3 Zinc knuckle zf-CCHC_2 PF13696.1 CCD22390.1 - 1.6 8.3 28.9 0.6 9.6 1.4 4.6 2 1 3 5 5 5 0 Zinc knuckle tRNA-synt_2b PF00587.20 CCD22391.1 - 8.5e-46 155.6 0.4 1.8e-45 154.6 0.2 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCD22391.1 - 3.1e-21 75.1 1.0 7.7e-21 73.8 0.7 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 CCD22391.1 - 1.7e-15 56.5 0.0 4.6e-15 55.2 0.0 1.7 2 0 0 2 2 2 1 TGS domain tRNA_SAD PF07973.9 CCD22391.1 - 4.6e-13 48.8 0.0 9.2e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF1689 PF07954.6 CCD22392.1 - 2.8e-45 153.8 0.9 4.4e-45 153.2 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) Coatomer_E PF04733.9 CCD22393.1 - 1.1e-11 44.5 8.6 2.2e-11 43.4 6.0 1.5 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_1 PF00515.23 CCD22393.1 - 0.0097 15.4 2.0 0.07 12.7 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCD22393.1 - 0.24 11.3 1.7 5.8 7.0 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Phage_connect_1 PF05135.8 CCD22393.1 - 0.3 11.2 3.8 8.9 6.5 0.3 3.2 2 1 1 3 3 3 0 Phage gp6-like head-tail connector protein 2-Hacid_dh_C PF02826.14 CCD22394.1 - 1.3e-53 180.7 0.0 3.1e-53 179.5 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCD22394.1 - 6.1e-37 126.0 0.1 7.9e-37 125.6 0.1 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 CCD22394.1 - 2e-05 24.5 0.1 4.3e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 CCD22394.1 - 2.6e-05 24.1 0.4 7e-05 22.7 0.3 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 CCD22394.1 - 0.011 16.0 0.1 0.092 13.0 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain Acetyltransf_1 PF00583.19 CCD22394.1 - 0.013 15.5 0.0 0.055 13.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family IlvN PF07991.7 CCD22394.1 - 0.025 13.9 0.2 0.079 12.3 0.1 1.9 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain ACT PF01842.20 CCD22394.1 - 0.026 13.9 0.0 0.086 12.3 0.0 1.9 1 0 0 1 1 1 0 ACT domain 3HCDH_N PF02737.13 CCD22394.1 - 0.089 12.4 0.1 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SPO22 PF08631.5 CCD22395.1 - 1.4e-56 191.6 10.5 1.4e-56 191.6 7.3 3.4 3 0 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like DNA_ligase_A_M PF01068.16 CCD22396.1 - 0.047 13.0 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 ATP dependent DNA ligase domain DUF4611 PF15387.1 CCD22396.1 - 0.056 13.5 3.7 0.13 12.3 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) HORMA PF02301.13 CCD22397.1 - 2.4e-49 167.6 1.6 6e-49 166.3 1.1 1.7 1 0 0 1 1 1 1 HORMA domain PHD_2 PF13831.1 CCD22397.1 - 0.011 15.0 5.2 0.03 13.6 3.6 1.7 1 0 0 1 1 1 0 PHD-finger PCI PF01399.22 CCD22398.1 - 0.0033 17.7 0.1 0.0033 17.7 0.1 2.7 2 1 1 3 3 3 1 PCI domain MAM33 PF02330.11 CCD22399.1 - 1.4e-49 168.6 9.8 1.6e-49 168.4 6.8 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Ribosomal_S24e PF01282.14 CCD22400.1 - 3.1e-35 119.8 0.1 4.7e-35 119.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e LCCL PF03815.14 CCD22401.1 - 7.3e-08 32.3 0.1 1.2e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 LCCL domain Fst_toxin PF13955.1 CCD22401.1 - 0.14 11.8 2.2 0.34 10.6 1.5 1.6 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system DUF997 PF06196.7 CCD22401.1 - 1.4 8.4 7.8 0.12 11.9 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Ribonuc_red_lgC PF02867.10 CCD22402.1 - 3.6e-212 705.6 0.0 4.5e-212 705.3 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CCD22402.1 - 1.6e-23 82.2 0.0 4.2e-23 80.9 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CCD22402.1 - 9.1e-17 61.2 0.1 2.9e-16 59.6 0.0 2.0 2 0 0 2 2 2 1 ATP cone domain Fis1_TPR_C PF14853.1 CCD22403.1 - 3e-24 84.6 0.4 6e-24 83.6 0.3 1.5 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CCD22403.1 - 1.2e-14 53.2 0.0 2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.1 CCD22403.1 - 0.0038 17.5 0.0 0.017 15.4 0.0 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCD22403.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Methyltransf_31 PF13847.1 CCD22404.1 - 7.1e-25 87.3 0.5 1.2e-24 86.6 0.1 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD22404.1 - 3.4e-20 72.7 0.0 5.2e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCD22404.1 - 3.6e-07 30.5 0.0 7.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD22404.1 - 4.3e-07 30.2 0.0 7.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCD22404.1 - 7.1e-07 29.6 0.0 1.4e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCD22404.1 - 1.1e-06 28.5 0.0 1.8e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCD22404.1 - 2.1e-06 27.4 0.0 3.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCD22404.1 - 3.2e-06 26.6 0.0 5.7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CCD22404.1 - 0.00012 21.8 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.3 CCD22404.1 - 0.0022 16.9 0.0 0.0062 15.4 0.0 1.6 1 1 1 2 2 2 1 Putative methyltransferase PCMT PF01135.14 CCD22404.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 CCD22404.1 - 0.03 13.6 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 CCD22404.1 - 0.032 13.2 0.0 0.072 12.1 0.0 1.4 1 1 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 CCD22404.1 - 0.054 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GCD14 PF08704.5 CCD22404.1 - 0.092 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Ran_BP1 PF00638.13 CCD22405.1 - 7.6e-34 116.3 0.0 2.2e-33 114.9 0.0 1.8 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 CCD22405.1 - 0.0034 17.0 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 WH1 domain DUF2578 PF10843.3 CCD22406.1 - 1.1e-66 224.3 13.9 1.3e-66 224.0 9.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) TonB_2 PF13103.1 CCD22406.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 TonB C terminal Vhr1 PF04001.8 CCD22407.1 - 1e-44 150.3 2.8 1e-44 150.3 2.0 1.8 2 0 0 2 2 2 1 Transcription factor Vhr1 PAT1 PF09770.4 CCD22408.1 - 8.7 4.4 34.5 16 3.5 23.9 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TPP_enzyme_M PF00205.17 CCD22409.1 - 1.5e-34 118.7 0.0 5.5e-34 116.8 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 CCD22409.1 - 3e-32 111.4 0.0 4.8e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCD22409.1 - 1.5e-14 53.8 0.0 2.8e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 CCD22409.1 - 0.0028 17.2 0.0 0.0077 15.7 0.0 1.7 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit SAP PF02037.22 CCD22410.1 - 1.5e-10 40.2 2.4 2.2e-10 39.7 0.2 2.4 3 0 0 3 3 3 1 SAP domain HeH PF12949.2 CCD22410.1 - 0.031 13.8 0.0 0.07 12.6 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain HAD_2 PF13419.1 CCD22411.1 - 7.9e-11 42.4 0.0 1.1e-10 42.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCD22411.1 - 3e-08 34.3 0.0 4.8e-07 30.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCD22411.1 - 2.3e-07 30.4 0.0 4.5e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like DUF3885 PF13021.1 CCD22411.1 - 0.046 13.4 0.2 0.15 11.7 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3885) HAD PF12710.2 CCD22411.1 - 0.13 12.3 0.0 0.19 11.8 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_L34e PF01199.13 CCD22412.1 - 7.5e-37 125.4 4.7 7.5e-37 125.4 3.2 1.4 2 0 0 2 2 2 1 Ribosomal protein L34e EndIII_4Fe-2S PF10576.4 CCD22412.1 - 0.098 12.8 1.9 0.22 11.7 0.1 2.3 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Ribonuc_L-PSP PF01042.16 CCD22413.1 - 4e-43 146.0 0.6 4.7e-43 145.7 0.4 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cyclin PF08613.6 CCD22414.1 - 1.1e-44 152.4 2.9 1.1e-44 152.4 2.0 2.4 2 1 0 2 2 2 1 Cyclin Transp_cyt_pur PF02133.10 CCD22415.1 - 8.6e-93 311.2 42.5 9.9e-93 311.0 29.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Steroid_dh PF02544.11 CCD22416.1 - 4.3e-08 33.0 10.0 4.3e-08 33.0 6.9 2.3 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase RhoGAP PF00620.22 CCD22416.1 - 0.042 13.4 0.1 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 RhoGAP domain L27 PF02828.11 CCD22416.1 - 0.077 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 L27 domain DUF4149 PF13664.1 CCD22416.1 - 0.33 11.0 4.7 0.13 12.2 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) E1-E2_ATPase PF00122.15 CCD22417.1 - 5.7e-27 94.2 0.0 1.2e-26 93.2 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCD22417.1 - 2.1e-14 54.4 0.1 6.6e-13 49.5 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCD22417.1 - 3.7e-10 40.2 0.6 1.2e-09 38.6 0.3 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCD22417.1 - 1.1e-08 34.9 0.0 2.7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCD22417.1 - 0.0031 17.1 1.0 0.017 14.6 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase EXS PF03124.9 CCD22418.1 - 7.1e-88 294.9 34.2 1.2e-87 294.1 23.7 1.4 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CCD22418.1 - 1.1e-28 100.8 71.5 6.3e-25 88.4 51.0 3.9 2 1 0 2 2 2 1 SPX domain WD40 PF00400.27 CCD22419.1 - 1.5e-50 167.2 23.2 3.1e-10 39.5 0.7 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CCD22419.1 - 1.9e-12 46.0 10.0 0.0026 15.9 0.3 5.3 1 1 3 5 5 5 5 Nucleoporin Nup120/160 F-box-like PF12937.2 CCD22419.1 - 3.4e-12 45.8 1.8 6.4e-12 44.9 1.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCD22419.1 - 4.8e-08 32.4 2.7 1.1e-07 31.3 1.9 1.6 1 0 0 1 1 1 1 F-box domain CBM_21 PF03370.8 CCD22420.1 - 1.1e-28 99.4 7.9 3.1e-28 98.0 5.3 2.0 1 1 0 1 1 1 1 Putative phosphatase regulatory subunit DNA_pol_phi PF04931.8 CCD22420.1 - 3.2 5.4 11.1 5.6 4.6 7.7 1.4 1 0 0 1 1 1 0 DNA polymerase phi ArfGap PF01412.13 CCD22421.1 - 1.4e-36 124.7 0.4 1.4e-36 124.7 0.3 3.0 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf NAD_binding_1 PF00175.16 CCD22422.1 - 1e-28 100.0 0.1 2.7e-28 98.7 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCD22422.1 - 1.5e-27 95.5 0.0 2.4e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CCD22422.1 - 2.7e-05 24.0 0.0 0.08 12.8 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 CCD22422.1 - 0.0031 17.4 0.0 0.0051 16.7 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain BCDHK_Adom3 PF10436.4 CCD22423.1 - 1.9e-25 89.2 0.5 4.7e-25 87.9 0.3 1.7 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCD22423.1 - 1.5e-15 56.8 0.0 7.5e-14 51.3 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCD22423.1 - 0.003 17.2 0.0 0.0066 16.1 0.0 1.7 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 CCD22423.1 - 0.015 15.1 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain BAR_2 PF10455.4 CCD22424.1 - 4.4e-77 258.8 21.3 4.4e-77 258.8 14.8 1.6 2 0 0 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking DUF3439 PF11921.3 CCD22424.1 - 0.0048 16.6 1.4 0.0048 16.6 1.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) IFT46_B_C PF12317.3 CCD22424.1 - 0.028 13.7 0.1 0.028 13.7 0.1 2.3 2 1 0 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal Apq12 PF12716.2 CCD22425.1 - 0.013 15.1 11.7 0.013 15.1 8.1 2.2 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis Metallophos PF00149.23 CCD22426.1 - 5.9e-30 104.1 8.4 1e-29 103.3 5.8 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Not3 PF04065.10 CCD22427.1 - 1.3e-90 302.7 27.9 1.3e-90 302.7 19.4 2.6 2 1 1 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CCD22427.1 - 2.2e-25 89.0 0.3 1.1e-24 86.8 0.2 2.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.1 CCD22427.1 - 0.0064 16.5 1.6 0.0064 16.5 1.1 4.8 5 0 0 5 5 5 1 Syntaxin-like protein UBN2 PF14223.1 CCD22428.1 - 0.018 14.8 3.5 0.99 9.2 0.5 2.6 1 1 1 2 2 2 0 gag-polypeptide of LTR copia-type Clathrin-link PF09268.5 CCD22428.1 - 0.62 9.1 4.9 0.15 11.1 0.5 2.3 2 0 0 2 2 2 0 Clathrin, heavy-chain linker SAP18 PF06487.7 CCD22428.1 - 0.87 9.3 7.5 0.28 10.9 2.3 2.3 2 1 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) FAM104 PF15434.1 CCD22428.1 - 3.5 7.8 12.8 0.28 11.4 4.6 2.2 2 0 0 2 2 2 0 Family 104 YesK PF14150.1 CCD22428.1 - 9.2 6.4 9.7 19 5.4 2.4 2.7 2 0 0 2 2 2 0 YesK-like protein bZIP_1 PF00170.16 CCD22429.1 - 6.9e-14 51.5 8.6 1.9e-13 50.1 6.0 1.8 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCD22429.1 - 1.5e-06 27.9 7.0 6.9e-06 25.7 4.8 2.2 1 0 0 1 1 1 1 Basic region leucine zipper Pkinase PF00069.20 CCD22430.1 - 5.5e-55 186.3 3.5 1.2e-53 181.9 2.4 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22430.1 - 3.6e-19 68.8 0.2 7.9e-14 51.3 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CCD22430.1 - 2e-05 24.4 0.1 0.00013 21.8 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCD22430.1 - 0.016 14.7 0.2 0.016 14.7 0.1 2.3 3 0 0 3 3 3 0 Choline/ethanolamine kinase Kdo PF06293.9 CCD22430.1 - 0.11 11.5 0.4 0.28 10.2 0.3 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF496 PF04363.7 CCD22430.1 - 0.14 11.9 2.9 0.85 9.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF496) cNMP_binding PF00027.24 CCD22431.1 - 6.8e-44 147.6 0.1 8.5e-23 79.9 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain PfkB PF00294.19 CCD22431.1 - 0.031 13.4 0.0 0.068 12.2 0.0 1.5 2 0 0 2 2 2 0 pfkB family carbohydrate kinase Cupin_2 PF07883.6 CCD22431.1 - 0.054 12.9 3.7 1.3 8.5 0.0 2.7 3 0 0 3 3 3 0 Cupin domain CBM_25 PF03423.8 CCD22432.1 - 0.027 14.5 0.1 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Zip PF02535.17 CCD22433.1 - 5.3e-53 180.0 12.5 5.3e-53 180.0 8.7 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter DUF456 PF04306.8 CCD22433.1 - 0.16 12.0 4.1 0.73 9.8 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF456) DUF2946 PF11162.3 CCD22433.1 - 0.25 11.5 1.0 5.3 7.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Bap31 PF05529.7 CCD22433.1 - 4.7 6.6 7.0 5.5 6.3 0.2 2.6 2 1 1 3 3 3 0 B-cell receptor-associated protein 31-like MMgT PF10270.4 CCD22434.1 - 1.4e-19 70.5 0.6 2.8e-19 69.4 0.4 1.5 1 1 0 1 1 1 1 Membrane magnesium transporter RINGv PF12906.2 CCD22435.1 - 6.5e-15 54.9 5.7 1.2e-14 54.0 3.9 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CCD22435.1 - 0.029 14.1 4.8 0.061 13.1 3.3 1.6 1 0 0 1 1 1 0 Ring finger domain Peptidase_C48 PF02902.14 CCD22436.1 - 9.9e-38 129.9 2.6 9.9e-38 129.9 1.8 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain EF-hand_4 PF12763.2 CCD22437.1 - 2.9e-22 78.3 0.0 2.7e-10 39.9 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CCD22437.1 - 6.6e-06 26.1 0.0 0.0036 17.3 0.1 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CCD22437.1 - 1.5e-05 23.9 0.0 0.26 10.6 0.0 3.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 CCD22437.1 - 0.00011 21.7 0.0 4.5 7.4 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain FAM150 PF15129.1 CCD22437.1 - 0.023 14.6 0.1 0.023 14.6 0.1 2.7 3 0 0 3 3 3 0 FAM150 family DUF2701 PF10857.3 CCD22437.1 - 0.3 10.8 0.2 0.86 9.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) RRM_1 PF00076.17 CCD22438.1 - 5.8e-21 73.9 0.0 1.2e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD22438.1 - 2.3e-14 53.1 0.0 3.6e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD22438.1 - 9.1e-10 38.2 0.0 1.6e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DnaJ-X PF14308.1 CCD22439.1 - 1.3e-65 220.4 4.1 1.3e-65 220.4 2.8 2.3 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CCD22439.1 - 5.9e-25 86.7 1.2 5.9e-25 86.7 0.9 2.4 2 0 0 2 2 2 1 DnaJ domain TEX15 PF15326.1 CCD22439.1 - 0.77 9.3 13.5 0.31 10.6 6.7 2.0 2 0 0 2 2 2 0 Testis expressed sequence 15 Pex16 PF08610.5 CCD22439.1 - 2.1 7.2 8.4 4.1 6.3 5.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Apt1 PF10351.4 CCD22439.1 - 3.4 6.4 20.0 0.11 11.3 0.1 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain ANTH PF07651.11 CCD22440.1 - 2.2e-58 197.1 0.9 2.2e-58 197.1 0.6 2.6 3 0 0 3 3 3 1 ANTH domain ENTH PF01417.15 CCD22440.1 - 1.2e-06 28.4 4.3 1.6e-06 28.0 0.2 2.7 2 1 0 2 2 2 1 ENTH domain PAT1 PF09770.4 CCD22440.1 - 0.043 12.0 28.4 0.065 11.4 19.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Slu7 PF11708.3 CCD22440.1 - 3 7.5 11.8 0.12 12.0 3.5 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor D123 PF07065.9 CCD22441.1 - 2.3e-112 374.9 4.5 3.3e-112 374.4 3.1 1.2 1 0 0 1 1 1 1 D123 CDP-OH_P_transf PF01066.16 CCD22442.1 - 9.5e-17 61.1 6.8 1.4e-16 60.6 4.7 1.4 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Pro_isomerase PF00160.16 CCD22443.1 - 5.1e-45 153.4 0.9 6.2e-45 153.1 0.1 1.5 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 PF00515.23 CCD22443.1 - 4.6e-05 22.8 1.3 0.00024 20.5 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCD22443.1 - 6.4e-05 22.5 0.7 0.0027 17.5 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCD22443.1 - 0.00012 21.6 3.1 0.038 13.6 0.1 2.4 2 1 0 2 2 2 2 TPR repeat TPR_9 PF13371.1 CCD22443.1 - 0.025 14.4 0.4 0.047 13.5 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCD22443.1 - 0.088 12.6 0.0 0.088 12.6 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCD22443.1 - 0.12 12.9 0.2 0.12 12.9 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat CHCH PF06747.8 CCD22444.1 - 1.8e-06 27.6 7.9 2.9e-06 27.0 5.5 1.3 1 0 0 1 1 1 1 CHCH domain DUF3782 PF12644.2 CCD22444.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Sec31 PF11549.3 CCD22445.1 - 1.5e-20 72.5 1.9 1.5e-20 72.5 1.3 2.3 2 0 0 2 2 2 1 Protein transport protein SEC31 WD40 PF00400.27 CCD22445.1 - 5.6e-11 41.8 14.0 0.24 11.3 0.0 7.9 8 0 0 8 8 8 4 WD domain, G-beta repeat SRA1 PF07304.6 CCD22445.1 - 6.7e-06 25.9 0.0 2.9e-05 23.8 0.0 2.2 1 1 0 1 1 1 1 Steroid receptor RNA activator (SRA1) eIF2A PF08662.6 CCD22445.1 - 0.00011 21.9 0.8 0.0011 18.7 0.1 2.4 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Prp18 PF02840.10 CCD22445.1 - 0.038 13.8 0.2 0.25 11.1 0.2 2.3 3 0 0 3 3 3 0 Prp18 domain Sugar_tr PF00083.19 CCD22446.1 - 1.2e-127 426.1 30.3 1.5e-127 425.9 21.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD22446.1 - 2.1e-21 76.0 35.4 8.2e-15 54.3 9.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.8 CCD22446.1 - 1.4 8.9 9.9 1.2 9.1 0.4 3.4 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Prenyltransf PF01255.14 CCD22447.1 - 6.3e-05 22.2 0.0 0.00013 21.2 0.0 1.5 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Arf PF00025.16 CCD22448.1 - 3.2e-78 260.9 0.0 3.7e-78 260.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCD22448.1 - 2.2e-14 53.1 0.0 2.4e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCD22448.1 - 6.1e-14 51.6 0.0 7.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCD22448.1 - 4.3e-11 42.1 0.5 4.8e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCD22448.1 - 8.6e-11 41.4 0.0 1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCD22448.1 - 1.4e-10 41.6 0.0 2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCD22448.1 - 8.6e-06 25.6 0.0 1.3e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCD22448.1 - 0.0058 16.0 0.0 0.027 13.8 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 CCD22448.1 - 0.006 16.0 0.2 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CCD22448.1 - 0.0071 16.2 0.1 0.011 15.5 0.1 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CCD22448.1 - 0.02 14.5 0.5 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 CCD22448.1 - 0.031 14.5 0.1 0.058 13.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.13 CCD22448.1 - 0.037 13.0 0.1 0.056 12.5 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.14 CCD22448.1 - 0.075 12.4 0.1 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Vps5 PF09325.5 CCD22449.1 - 5.6e-39 133.7 14.4 8.3e-39 133.2 10.0 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CCD22449.1 - 2.2e-10 40.2 0.1 7.4e-10 38.6 0.1 1.9 1 0 0 1 1 1 1 PX domain Ufd2P_core PF10408.4 CCD22450.1 - 1.2e-177 592.0 17.0 1.2e-177 592.0 11.8 1.6 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.10 CCD22450.1 - 2e-27 94.9 1.0 2e-27 94.9 0.7 2.3 3 0 0 3 3 3 1 U-box domain IL28A PF15177.1 CCD22450.1 - 0.026 14.0 0.1 0.088 12.3 0.0 1.9 2 0 0 2 2 2 0 Interleukin-28A R3H PF01424.17 CCD22451.1 - 6.1e-09 35.4 0.1 1.4e-08 34.2 0.1 1.6 1 0 0 1 1 1 1 R3H domain Metallophos PF00149.23 CCD22452.1 - 1.8e-40 138.4 0.6 2.4e-40 138.0 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_108 PF05838.7 CCD22452.1 - 0.097 12.7 0.2 6.7 6.9 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase 108 Ribosomal_L41 PF05162.8 CCD22454.1 - 3.4e-09 36.1 25.8 3.6e-09 36.1 17.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 DUF1601 PF07671.6 CCD22454.1 - 0.25 10.9 1.7 0.28 10.8 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1601) Mit_KHE1 PF10173.4 CCD22455.1 - 1.1e-54 185.1 1.0 1.6e-54 184.6 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related DUF2779 PF11074.3 CCD22455.1 - 0.1 12.6 2.0 0.52 10.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function(DUF2779) HMGL-like PF00682.14 CCD22456.1 - 8.8e-75 251.4 0.1 1.7e-74 250.4 0.1 1.5 1 0 0 1 1 1 1 HMGL-like Ribosomal_60s PF00428.14 CCD22457.1 - 3.4e-23 81.8 14.0 4.1e-23 81.5 9.7 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 CCD22457.1 - 0.0056 16.3 0.6 0.0067 16.0 0.4 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region Med15_fungi PF05397.7 CCD22458.1 - 0.094 12.6 0.1 0.21 11.5 0.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 15 Na_Ca_ex PF01699.19 CCD22459.1 - 2e-51 173.2 32.5 3.3e-26 91.5 4.9 2.5 3 0 0 3 3 3 2 Sodium/calcium exchanger protein YWFCY PF14293.1 CCD22459.1 - 0.017 14.9 0.1 0.084 12.7 0.0 2.3 2 0 0 2 2 2 0 YWFCY protein DUF4029 PF13221.1 CCD22459.1 - 0.13 12.6 3.8 2.5 8.5 0.1 3.7 3 1 0 4 4 4 0 Protein of unknown function (DUF4029) Cyclin_N PF00134.18 CCD22460.1 - 5.5e-09 35.6 0.1 1.2e-08 34.5 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCD22460.1 - 1.1e-08 35.6 0.8 1.1e-08 35.6 0.5 2.2 2 1 0 2 2 2 1 Cyclin AAA PF00004.24 CCD22461.1 - 1.5e-98 326.1 0.0 3.4e-48 163.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CCD22461.1 - 5e-18 64.8 0.1 1.6e-17 63.1 0.1 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 CCD22461.1 - 1.5e-13 50.9 0.2 4.2e-07 30.0 0.0 3.2 3 1 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CCD22461.1 - 2.5e-13 49.6 0.0 1.8e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CCD22461.1 - 4.9e-13 48.9 0.6 2.2e-06 27.4 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCD22461.1 - 2.8e-12 47.0 0.1 0.00045 20.2 0.0 4.2 3 1 1 4 4 4 2 AAA ATPase domain AAA_33 PF13671.1 CCD22461.1 - 4.4e-11 42.8 0.0 1.4e-05 24.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCD22461.1 - 6.9e-11 42.4 3.0 0.00093 19.3 0.1 4.6 3 2 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CCD22461.1 - 7.1e-11 42.9 0.0 0.0013 19.5 0.0 3.4 4 0 0 4 4 2 2 AAA domain TIP49 PF06068.8 CCD22461.1 - 2.9e-09 36.1 0.1 0.0012 17.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 CCD22461.1 - 2.6e-08 33.7 0.0 0.004 17.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CCD22461.1 - 9.1e-08 31.7 0.1 0.0073 15.7 0.0 2.9 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 CCD22461.1 - 1.3e-07 31.2 5.8 0.0055 16.1 0.3 4.2 2 2 1 3 3 3 2 AAA domain AAA_19 PF13245.1 CCD22461.1 - 1.9e-07 30.7 1.1 0.021 14.5 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 CCD22461.1 - 2.6e-07 30.7 0.0 0.01 16.0 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 CCD22461.1 - 2.8e-07 29.9 0.4 0.022 13.9 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CCD22461.1 - 4.9e-07 29.0 0.0 0.014 14.5 0.0 3.1 4 0 0 4 4 3 2 Zeta toxin CDC48_2 PF02933.12 CCD22461.1 - 4.9e-07 29.2 0.1 1.3e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 KaiC PF06745.8 CCD22461.1 - 6.7e-07 28.6 1.1 0.23 10.5 0.0 3.6 2 1 1 3 3 3 2 KaiC ResIII PF04851.10 CCD22461.1 - 1.2e-06 28.4 1.8 0.009 15.8 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 CCD22461.1 - 2.3e-06 27.3 0.0 0.11 12.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_11 PF13086.1 CCD22461.1 - 5.3e-06 26.1 0.0 0.16 11.5 0.0 2.9 2 1 0 2 2 2 2 AAA domain ABC_tran PF00005.22 CCD22461.1 - 9.6e-06 25.9 0.3 0.092 13.0 0.0 4.3 3 1 0 3 3 3 1 ABC transporter Sigma54_activat PF00158.21 CCD22461.1 - 1e-05 25.0 0.1 0.11 11.9 0.0 3.6 3 1 0 3 3 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 CCD22461.1 - 1.1e-05 25.5 0.0 0.25 11.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCD22461.1 - 1.3e-05 25.4 0.3 0.2 11.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain Bac_DnaA PF00308.13 CCD22461.1 - 2.1e-05 24.3 0.0 0.11 12.0 0.0 3.4 3 0 0 3 3 3 1 Bacterial dnaA protein Vps4_C PF09336.5 CCD22461.1 - 2.2e-05 24.2 0.1 0.00052 19.8 0.0 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain PhoH PF02562.11 CCD22461.1 - 2.4e-05 23.6 0.5 0.11 11.7 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.12 CCD22461.1 - 3e-05 23.0 0.1 0.13 11.1 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 CCD22461.1 - 3.4e-05 23.9 0.0 0.17 11.8 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 CCD22461.1 - 4e-05 22.6 0.0 0.074 11.9 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CCD22461.1 - 9.9e-05 22.1 0.1 0.36 10.4 0.0 3.9 2 2 1 3 3 3 1 Archaeal ATPase AAA_3 PF07726.6 CCD22461.1 - 0.00011 21.7 0.0 0.65 9.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCD22461.1 - 0.00013 21.6 0.1 1.7 8.3 0.0 3.6 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 CCD22461.1 - 0.00044 19.3 0.0 0.7 8.8 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CCD22461.1 - 0.00066 19.3 0.0 1.7 8.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 CCD22461.1 - 0.0059 15.5 0.1 1.9 7.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 CCD22461.1 - 0.0096 15.6 1.7 3.4 7.3 0.0 4.3 4 1 0 4 4 4 0 NTPase KAP_NTPase PF07693.9 CCD22461.1 - 0.013 14.5 0.1 1.8 7.4 0.0 3.0 2 2 1 3 3 3 0 KAP family P-loop domain IPT PF01745.11 CCD22461.1 - 0.015 14.4 0.1 1.9 7.6 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase Zot PF05707.7 CCD22461.1 - 0.025 14.0 0.4 5.7 6.3 0.1 3.5 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) SKI PF01202.17 CCD22461.1 - 0.047 13.5 1.6 4.7 7.0 0.0 3.3 3 0 0 3 3 3 0 Shikimate kinase UPF0079 PF02367.12 CCD22461.1 - 0.062 12.9 0.1 7.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 CCD22461.1 - 0.1 12.1 0.0 16 4.9 0.0 3.4 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 CCD22461.1 - 0.13 11.7 0.3 25 4.2 0.0 3.5 3 1 1 4 4 4 0 DEAD/DEAH box helicase Hom_end_hint PF05203.11 CCD22461.1 - 0.28 10.8 3.1 0.53 9.9 2.1 1.3 1 0 0 1 1 1 0 Hom_end-associated Hint HIT PF01230.18 CCD22462.1 - 1.1e-19 70.8 0.1 1.8e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CCD22462.1 - 2.5e-06 27.7 0.5 3.7e-06 27.1 0.1 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CCD22462.1 - 0.051 13.2 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 FAD-oxidase_C PF02913.14 CCD22463.1 - 1.8e-41 142.1 0.0 2.7e-41 141.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCD22463.1 - 2.6e-31 107.9 0.0 4e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain zf-CCHC PF00098.18 CCD22464.1 - 0.0022 17.8 5.0 0.004 17.0 3.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CCD22464.1 - 0.049 13.2 2.7 0.13 11.9 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle DNase-RNase PF02577.9 CCD22464.1 - 0.091 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Bifunctional nuclease GET2 PF08690.5 CCD22465.1 - 5.2e-84 282.0 0.8 6.3e-84 281.7 0.5 1.1 1 0 0 1 1 1 1 GET complex subunit GET2 Arc_PepC PF06819.6 CCD22465.1 - 0.12 12.3 0.1 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal Peptidase A24 C-terminal Domain MRAP PF15183.1 CCD22465.1 - 3.5 7.2 6.6 1.9 8.1 0.4 2.3 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family BING4CT PF08149.6 CCD22466.1 - 4.6e-39 131.7 0.1 3.2e-37 125.8 0.0 3.4 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 CCD22466.1 - 1.8e-06 27.5 0.0 8.8e-05 22.2 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat UPF0240 PF06784.6 CCD22466.1 - 4.2 7.0 10.2 0.77 9.4 0.8 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0240) PC_rep PF01851.17 CCD22467.1 - 1.5e-33 113.0 16.4 9.2e-05 22.4 0.0 10.0 10 0 0 10 10 10 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CCD22467.1 - 6.3e-15 55.2 1.5 4.2e-12 46.1 0.0 3.9 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 CCD22467.1 - 3.5e-07 30.5 1.8 0.014 15.8 0.1 4.6 3 1 1 4 4 4 2 HEAT-like repeat HEAT PF02985.17 CCD22467.1 - 4.3e-06 26.3 0.8 1.9 8.8 0.0 4.7 5 0 0 5 5 5 2 HEAT repeat RICTOR_V PF14668.1 CCD22467.1 - 0.029 14.2 0.6 0.67 9.9 0.0 3.3 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 FAM176 PF14851.1 CCD22467.1 - 0.86 9.2 5.1 1.6 8.4 3.5 1.3 1 0 0 1 1 1 0 FAM176 family Med19 PF10278.4 CCD22467.1 - 4.8 6.8 15.2 6.7 6.3 9.9 1.7 2 0 0 2 2 2 0 Mediator of RNA pol II transcription subunit 19 2-Hacid_dh_C PF02826.14 CCD22468.1 - 2e-53 180.1 0.0 3.4e-53 179.4 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCD22468.1 - 1.5e-37 128.0 0.1 2e-37 127.6 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCD22468.1 - 3.2e-06 27.0 1.4 4.6e-06 26.5 0.2 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 CCD22468.1 - 4e-05 23.5 0.0 7.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Acetyltransf_1 PF00583.19 CCD22468.1 - 0.011 15.7 0.0 0.064 13.3 0.0 2.4 2 1 1 3 3 3 0 Acetyltransferase (GNAT) family IlvN PF07991.7 CCD22468.1 - 0.015 14.7 0.1 0.03 13.6 0.1 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain XdhC_C PF13478.1 CCD22468.1 - 0.026 14.8 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 XdhC Rossmann domain ACT PF01842.20 CCD22468.1 - 0.066 12.7 0.1 0.38 10.3 0.0 2.3 1 1 0 1 1 1 0 ACT domain 3HCDH_N PF02737.13 CCD22468.1 - 0.074 12.7 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain APH PF01636.18 CCD22469.1 - 3.6e-07 30.1 0.0 1.6e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCD22469.1 - 0.003 16.6 0.0 2.1 7.3 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Sulfatase_C PF14707.1 CCD22469.1 - 0.0044 17.3 0.1 0.014 15.6 0.1 1.9 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Peptidase_M24 PF00557.19 CCD22470.1 - 1.1e-50 172.0 0.0 1.6e-50 171.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CCD22470.1 - 2e-31 108.1 0.0 3.7e-31 107.2 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF1798 PF08807.5 CCD22470.1 - 0.055 13.1 0.6 14 5.4 0.2 2.9 2 1 1 3 3 3 0 Bacterial domain of unknown function (DUF1798) PPR_2 PF13041.1 CCD22471.1 - 1.3e-14 53.8 0.4 1.3e-10 41.0 0.0 2.9 3 0 0 3 3 3 2 PPR repeat family Y_phosphatase PF00102.22 CCD22472.1 - 8.2e-47 159.5 0.1 1.4e-46 158.7 0.1 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 CCD22472.1 - 2.4e-09 37.5 0.0 1e-08 35.5 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain DSPc PF00782.15 CCD22472.1 - 0.018 14.6 0.0 0.083 12.4 0.0 2.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCD22472.1 - 0.061 13.5 0.0 0.28 11.4 0.0 2.1 2 0 0 2 2 2 0 Tyrosine phosphatase family Yos1 PF08571.5 CCD22473.1 - 2.5e-30 104.3 1.4 2.8e-30 104.2 0.9 1.0 1 0 0 1 1 1 1 Yos1-like Statherin PF03875.8 CCD22473.1 - 0.08 12.8 0.1 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Statherin Lactamase_B_2 PF12706.2 CCD22474.1 - 1.1e-38 132.7 0.0 1.9e-38 131.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CCD22474.1 - 1.6e-22 78.7 0.0 3.3e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 CCD22474.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DASH_Dad2 PF08654.5 CCD22475.1 - 4.8e-28 97.1 1.1 4.8e-28 97.1 0.7 1.4 2 0 0 2 2 2 1 DASH complex subunit Dad2 NuiA PF07924.6 CCD22475.1 - 0.023 14.5 0.1 1.4 8.8 0.0 2.1 1 1 1 2 2 2 0 Nuclease A inhibitor-like protein DUF4608 PF15381.1 CCD22475.1 - 0.14 12.2 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4608) Nucleoporin_N PF08801.6 CCD22476.1 - 2.8e-29 102.1 21.0 6.2e-29 100.9 14.6 1.6 1 0 0 1 1 1 1 Nup133 N terminal like Telomere_Sde2 PF13019.1 CCD22476.1 - 0.14 11.8 4.5 0.29 10.8 0.4 2.9 2 0 0 2 2 2 0 Telomere stability and silencing MRP-L20 PF12824.2 CCD22477.1 - 9.8e-43 145.9 1.7 1.3e-42 145.5 1.1 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HHH_3 PF12836.2 CCD22477.1 - 0.064 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix motif THF_DHG_CYH PF00763.18 CCD22478.1 - 9.9e-19 67.5 0.1 1.6e-18 66.8 0.1 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 CCD22478.1 - 7.5e-16 57.6 0.0 3.5e-10 39.1 0.0 2.8 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FTP PF07504.8 CCD22478.1 - 0.6 9.6 3.5 0.54 9.7 0.8 2.1 2 0 0 2 2 2 0 Fungalysin/Thermolysin Propeptide Motif Syntaxin-18_N PF10496.4 CCD22479.1 - 1.7e-15 56.5 1.0 5.3e-15 55.0 0.7 1.9 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 CCD22479.1 - 2.1e-05 24.0 7.1 4.9e-05 22.9 4.9 1.7 1 0 0 1 1 1 1 SNARE domain SecG PF03840.9 CCD22479.1 - 0.0026 17.4 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Preprotein translocase SecG subunit Nup54 PF13874.1 CCD22479.1 - 0.87 9.2 5.7 1.9 8.1 4.0 1.6 1 0 0 1 1 1 0 Nucleoporin complex subunit 54 DUF4559 PF15112.1 CCD22479.1 - 6.2 5.8 20.6 5.2 6.1 8.3 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4559) GTP_EFTU PF00009.22 CCD22480.1 - 8.8e-45 152.4 0.2 1.9e-44 151.3 0.0 1.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 CCD22480.1 - 2.2e-11 43.7 6.1 2.2e-11 43.7 4.2 2.1 2 0 0 2 2 2 1 HBS1 N-terminus MMR_HSR1 PF01926.18 CCD22480.1 - 9.4e-07 28.7 0.9 2.4e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 CCD22480.1 - 0.0002 21.4 0.1 0.0013 18.8 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain Miro PF08477.8 CCD22480.1 - 0.00087 19.7 2.5 0.0031 18.0 0.1 2.9 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU_D2 PF03144.20 CCD22480.1 - 0.0012 18.9 0.1 0.0032 17.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Dynamin_N PF00350.18 CCD22480.1 - 0.018 14.8 3.2 2.1 8.1 0.0 3.2 2 1 1 3 3 3 0 Dynamin family FeoB_N PF02421.13 CCD22480.1 - 0.15 11.3 2.0 1.7 7.9 0.1 3.3 3 2 0 3 3 3 0 Ferrous iron transport protein B Aldedh PF00171.17 CCD22482.1 - 1e-170 568.0 0.0 1.2e-170 567.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GST_N_2 PF13409.1 CCD22483.1 - 3.4e-22 78.2 0.0 1.2e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCD22483.1 - 1.3e-10 40.9 0.0 2.6e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCD22483.1 - 0.00066 19.8 0.0 0.96 9.7 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCD22483.1 - 0.014 15.3 0.1 0.12 12.3 0.1 2.1 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Formyl_trans_N PF00551.14 CCD22484.1 - 2.8e-23 82.3 0.0 4.2e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Acyltransferase PF01553.16 CCD22485.1 - 3.4e-10 39.4 0.0 1.8e-09 37.1 0.0 2.1 1 1 0 1 1 1 1 Acyltransferase YesK PF14150.1 CCD22485.1 - 2.6 8.1 9.4 0.19 11.8 1.9 2.4 2 0 0 2 2 2 0 YesK-like protein Occludin_ELL PF07303.8 CCD22486.1 - 0.037 14.7 2.6 0.11 13.2 1.8 1.8 1 0 0 1 1 1 0 Occludin homology domain DUF3336 PF11815.3 CCD22486.1 - 0.16 11.4 3.9 6.4 6.2 2.7 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3336) DUF972 PF06156.8 CCD22486.1 - 2 8.7 9.1 5.6 7.3 2.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF972) DUF3635 PF12330.3 CCD22487.1 - 4.8e-13 49.0 1.0 4.8e-13 49.0 0.7 3.4 2 2 1 3 3 3 1 Domain of unknown function (DUF3635) WD40 PF00400.27 CCD22488.1 - 5.2e-46 152.9 10.1 6.2e-10 38.5 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat HIRA_B PF09453.5 CCD22488.1 - 2.8e-08 33.0 0.8 1.2e-07 31.1 0.5 2.1 1 0 0 1 1 1 1 HIRA B motif Hira PF07569.6 CCD22488.1 - 1.1e-06 28.0 0.1 4.7e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 TUP1-like enhancer of split eIF2A PF08662.6 CCD22488.1 - 3.1e-06 27.0 0.9 0.21 11.2 0.1 4.8 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 CCD22488.1 - 1.8e-05 24.3 1.2 23 4.7 0.0 5.6 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PSII_BNR PF14870.1 CCD22488.1 - 0.024 13.6 0.0 0.29 10.0 0.0 2.1 1 1 1 2 2 2 0 Photosynthesis system II assembly factor YCF48 Nbas_N PF15492.1 CCD22488.1 - 0.11 11.6 1.4 0.36 9.9 0.0 2.6 5 0 0 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Aconitase PF00330.15 CCD22489.1 - 2.5e-184 613.1 0.0 3e-184 612.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCD22489.1 - 3.3e-45 153.4 0.0 6.2e-45 152.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain SH3_1 PF00018.23 CCD22490.1 - 6.4e-37 124.6 5.1 2.9e-12 45.7 0.0 4.3 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 CCD22490.1 - 7.2e-35 118.4 0.0 1.4e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 CCD22490.1 - 6.1e-33 112.1 7.3 3.5e-12 45.6 0.2 4.2 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 CCD22490.1 - 4.1e-31 106.2 0.1 2e-08 33.5 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain DUF3104 PF11302.3 CCD22490.1 - 0.0024 17.2 0.3 0.0093 15.3 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3104) SAM_1 PF00536.25 CCD22490.1 - 0.09 12.9 0.1 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Rsc14 PF08586.5 CCD22491.1 - 2.9e-29 101.5 0.2 5.5e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 RSC complex, Rsc14/Ldb7 subunit zf-CHY PF05495.7 CCD22491.1 - 0.011 15.8 0.4 0.019 15.1 0.2 1.4 1 0 0 1 1 1 0 CHY zinc finger ERG4_ERG24 PF01222.12 CCD22493.1 - 4.4e-181 602.1 30.9 5e-181 601.9 21.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family CytoC_RC PF02276.13 CCD22493.1 - 0.017 14.2 0.1 0.025 13.6 0.1 1.1 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit HEAT_EZ PF13513.1 CCD22494.1 - 3e-16 59.3 12.6 2.9e-09 37.1 0.0 8.1 7 2 2 9 9 9 2 HEAT-like repeat HEAT PF02985.17 CCD22494.1 - 2.5e-15 55.0 14.3 0.00039 20.2 0.1 9.5 9 0 0 9 9 9 3 HEAT repeat IBN_N PF03810.14 CCD22494.1 - 1.6e-13 50.3 4.6 5.5e-13 48.6 1.3 3.3 2 1 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 CCD22494.1 - 4e-09 36.6 15.1 1.2e-05 25.4 0.0 5.8 3 1 4 7 7 7 4 HEAT repeats CLASP_N PF12348.3 CCD22494.1 - 5.2e-07 29.2 0.6 3.7 6.8 0.0 5.7 3 2 3 6 6 6 4 CLASP N terminal Arm PF00514.18 CCD22494.1 - 0.0029 17.3 9.7 0.04 13.7 0.1 5.4 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Mito_carr PF00153.22 CCD22495.1 - 2.1e-56 187.6 0.6 2.9e-18 65.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_4 PF12799.2 CCD22496.1 - 0.0088 15.6 0.5 0.0088 15.6 0.4 5.8 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 CCD22496.1 - 0.051 13.7 13.4 16 6.2 0.1 6.9 7 0 0 7 7 7 0 Leucine rich repeat Fungal_trans PF04082.13 CCD22498.1 - 9.9e-23 80.3 1.9 9.9e-23 80.3 1.3 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD22498.1 - 3.2e-09 36.5 13.9 5.8e-09 35.7 9.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TylF PF05711.6 CCD22498.1 - 0.02 13.9 0.0 0.042 12.9 0.0 1.4 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) Fungal_trans PF04082.13 CCD22499.1 - 2.4e-31 108.5 3.5 5.7e-31 107.3 2.4 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD22499.1 - 7e-09 35.4 12.5 1.4e-08 34.4 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2789 PF10982.3 CCD22499.1 - 0.02 14.8 0.2 0.21 11.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2789) 6PF2K PF01591.13 CCD22500.1 - 1.1e-56 191.4 6.2 1.5e-56 190.9 4.3 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCD22500.1 - 9.3e-20 71.3 0.0 1.9e-19 70.3 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF1198 PF06711.6 CCD22500.1 - 0.11 12.3 0.6 0.89 9.3 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1198) AAA_33 PF13671.1 CCD22500.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCD22501.1 - 4e-34 117.8 0.1 7.7e-17 61.8 0.0 2.8 2 1 0 2 2 2 2 ABC transporter RLI PF04068.10 CCD22501.1 - 2.2e-15 55.9 4.5 5.6e-15 54.6 3.1 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 CCD22501.1 - 1.8e-12 47.8 11.1 0.0039 17.1 0.1 4.3 2 2 2 4 4 4 4 AAA domain AAA_15 PF13175.1 CCD22501.1 - 2.1e-07 30.3 0.2 0.22 10.5 0.0 3.4 3 1 0 3 3 3 2 AAA ATPase domain Fer4 PF00037.22 CCD22501.1 - 2.4e-07 30.0 3.8 2.4e-07 30.0 2.6 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain SMC_N PF02463.14 CCD22501.1 - 4.2e-07 29.4 2.1 0.12 11.5 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CCD22501.1 - 7e-06 26.2 0.0 0.0032 17.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCD22501.1 - 7.5e-06 25.3 0.6 0.13 11.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.24 CCD22501.1 - 8.7e-06 25.9 0.0 0.029 14.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CCD22501.1 - 1.4e-05 24.3 2.3 0.044 12.9 0.0 2.9 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCD22501.1 - 4.9e-05 23.4 0.0 0.01 15.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain NB-ARC PF00931.17 CCD22501.1 - 0.0001 21.2 0.0 0.052 12.4 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Miro PF08477.8 CCD22501.1 - 0.00012 22.5 0.2 0.82 10.1 0.0 3.1 2 1 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 CCD22501.1 - 0.00023 21.9 0.5 1.2 10.0 0.0 2.9 2 2 0 2 2 2 2 AAA domain Fer4_7 PF12838.2 CCD22501.1 - 0.00029 21.1 0.4 0.00029 21.1 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_18 PF13238.1 CCD22501.1 - 0.00033 20.9 0.1 1 9.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain Fer4_6 PF12837.2 CCD22501.1 - 0.00038 20.2 3.3 0.00038 20.2 2.3 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_25 PF13481.1 CCD22501.1 - 0.00038 19.9 0.1 0.23 10.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Fer4_21 PF14697.1 CCD22501.1 - 0.00083 19.1 12.3 0.0017 18.1 8.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.6 CCD22501.1 - 0.00087 18.8 0.0 0.56 9.6 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E NACHT PF05729.7 CCD22501.1 - 0.0022 17.6 1.3 0.28 10.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 CCD22501.1 - 0.0023 18.0 0.0 0.89 9.7 0.0 2.9 3 0 0 3 3 2 1 RNA helicase Fer4_2 PF12797.2 CCD22501.1 - 0.0026 17.5 2.4 0.0026 17.5 1.7 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_14 PF13173.1 CCD22501.1 - 0.0046 16.8 0.1 5.1 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CCD22501.1 - 0.005 16.5 1.1 0.047 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MobB PF03205.9 CCD22501.1 - 0.0051 16.5 0.7 1.1 8.9 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Fer4_3 PF12798.2 CCD22501.1 - 0.0058 17.1 4.2 0.0058 17.1 2.9 2.5 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_28 PF13521.1 CCD22501.1 - 0.0061 16.5 0.7 0.88 9.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CCD22501.1 - 0.0063 16.1 0.2 0.088 12.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Fer4_9 PF13187.1 CCD22501.1 - 0.0063 16.7 2.3 0.0063 16.7 1.6 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CCD22501.1 - 0.0092 15.7 1.4 0.0092 15.7 1.0 2.1 1 1 1 2 2 2 1 4Fe-4S dicluster domain Rad17 PF03215.10 CCD22501.1 - 0.0097 14.6 0.0 1.1 7.8 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Fer4_16 PF13484.1 CCD22501.1 - 0.012 16.3 0.3 0.012 16.3 0.2 2.6 2 1 1 3 3 1 0 4Fe-4S double cluster binding domain AAA_30 PF13604.1 CCD22501.1 - 0.02 14.4 0.1 0.57 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 CCD22501.1 - 0.024 14.5 0.1 9.5 6.2 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 CCD22501.1 - 0.025 14.4 0.0 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CCD22501.1 - 0.027 14.7 0.1 0.027 14.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.17 CCD22501.1 - 0.031 13.7 3.4 0.98 8.8 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Fer4_4 PF12800.2 CCD22501.1 - 0.042 14.2 2.2 0.042 14.2 1.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain MMR_HSR1 PF01926.18 CCD22501.1 - 0.052 13.5 0.1 5 7.1 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase IstB_IS21 PF01695.12 CCD22501.1 - 0.068 12.5 0.3 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.1 CCD22501.1 - 0.093 12.3 0.6 1.9 8.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CCD22501.1 - 0.1 12.0 0.1 9.2 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Fer4_17 PF13534.1 CCD22501.1 - 0.1 12.9 0.2 0.1 12.9 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain AAA_19 PF13245.1 CCD22501.1 - 0.12 12.1 2.0 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain DUF815 PF05673.8 CCD22501.1 - 0.13 11.2 0.1 4.8 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Thymidylate_kin PF02223.12 CCD22501.1 - 0.13 11.6 0.1 16 4.7 0.0 2.8 3 0 0 3 3 2 0 Thymidylate kinase PduV-EutP PF10662.4 CCD22501.1 - 0.16 11.4 1.4 0.48 9.9 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_8 PF13183.1 CCD22501.1 - 0.59 10.2 9.9 0.11 12.5 0.7 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain mRNA_triPase PF02940.10 CCD22502.1 - 1.1e-11 44.8 6.0 1.4e-11 44.5 4.2 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PQ-loop PF04193.9 CCD22503.1 - 8.5e-24 82.8 11.9 6.8e-19 67.1 1.4 2.7 2 0 0 2 2 2 2 PQ loop repeat ABC2_membrane_5 PF13346.1 CCD22503.1 - 1.6 7.9 22.8 0.033 13.4 7.4 2.3 1 1 1 2 2 2 0 ABC-2 family transporter protein ATG19_autophagy PF12744.2 CCD22504.1 - 9e-09 34.9 2.5 0.00094 18.5 0.0 2.5 2 1 0 2 2 2 2 Autophagy protein Atg19, Atg8-binding Dna2 PF08696.6 CCD22504.1 - 0.076 12.3 3.0 2 7.6 0.1 2.4 2 0 0 2 2 2 0 DNA replication factor Dna2 ANTH PF07651.11 CCD22504.1 - 1.6 7.4 7.6 3.6 6.2 2.0 2.2 2 0 0 2 2 2 0 ANTH domain Oxidored_q2 PF00420.19 CCD22505.1 - 0.5 9.9 0.0 0.5 9.9 0.0 2.6 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Slu7 PF11708.3 CCD22506.1 - 6.3e-43 147.2 21.7 6.3e-43 147.2 15.1 2.5 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.18 CCD22506.1 - 0.004 17.0 2.5 0.016 15.0 0.4 2.3 2 0 0 2 2 2 1 Zinc knuckle RPA_interact_N PF14766.1 CCD22506.1 - 0.059 12.8 2.2 2.9 7.4 0.2 2.8 2 0 0 2 2 2 0 Replication protein A interacting N-terminal DUF234 PF03008.9 CCD22506.1 - 0.13 12.4 6.2 0.049 13.7 0.9 2.7 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function Nop52 PF05997.7 CCD22507.1 - 5.9e-63 212.2 9.5 7.3e-63 211.8 6.6 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 TAN PF11640.3 CCD22507.1 - 0.036 13.7 0.7 0.58 9.8 0.1 2.6 2 1 0 2 2 2 0 Telomere-length maintenance and DNA damage repair DUF846 PF05832.7 CCD22509.1 - 1.2e-44 151.4 7.6 1.5e-44 151.1 5.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Methyltransf_8 PF05148.10 CCD22510.1 - 1.6e-58 197.9 12.1 7.6e-34 117.2 0.1 3.4 3 1 1 4 4 4 3 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CCD22510.1 - 1.1e-06 29.0 0.1 5.8e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain P_C PF06640.6 CCD22510.1 - 0.33 10.9 3.1 0.45 10.4 1.5 1.7 2 0 0 2 2 2 0 P protein C-terminus Stn1 PF10451.4 CCD22511.1 - 2.1e-45 154.5 1.0 2.1e-45 154.5 0.7 2.0 2 0 0 2 2 2 1 Telomere regulation protein Stn1 Stn1_C PF12659.2 CCD22511.1 - 2.5e-19 69.3 9.6 5.3e-19 68.2 6.7 1.6 1 0 0 1 1 1 1 Telomere capping C-terminal wHTH DUF3781 PF12636.2 CCD22511.1 - 0.18 11.8 4.6 0.5 10.3 3.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DDE_1 PF03184.14 CCD22512.1 - 2.3e-74 249.2 2.5 2.3e-74 249.2 1.7 1.8 2 0 0 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CCD22512.1 - 6.8e-14 51.4 0.2 6.8e-14 51.4 0.1 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.1 CCD22512.1 - 0.17 12.6 0.1 0.58 10.9 0.1 1.9 1 0 0 1 1 1 0 Homeodomain-like domain Clathrin PF00637.15 CCD22513.1 - 1.3e-28 99.3 0.6 1.3e-28 99.3 0.4 2.9 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_1 PF10366.4 CCD22513.1 - 2.9e-05 24.0 0.1 0.0001 22.2 0.0 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 WD40 PF00400.27 CCD22513.1 - 0.0007 19.3 2.4 0.0032 17.3 0.7 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Tbf5 PF06331.7 CCD22514.1 - 1.2e-27 95.4 0.1 1.3e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF1947 PF09183.5 CCD22515.1 - 0.042 13.6 0.7 0.087 12.6 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) Cwf_Cwc_15 PF04889.7 CCD22515.1 - 0.34 10.5 6.4 0.48 10.0 4.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Flocculin_t3 PF13928.1 CCD22517.1 - 0.02 15.0 22.3 0.02 15.0 15.4 6.8 4 2 2 6 6 6 0 Flocculin type 3 repeat DUF732 PF05305.9 CCD22517.1 - 0.036 14.1 1.4 2 8.5 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF732) KaiC PF06745.8 CCD22519.1 - 2.6e-08 33.2 0.1 2.6e-08 33.2 0.1 1.9 2 0 0 2 2 2 1 KaiC AAA_25 PF13481.1 CCD22519.1 - 1.3e-05 24.7 0.0 3.6e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 CCD22519.1 - 8.1e-05 21.6 0.0 0.00014 20.8 0.0 1.4 1 0 0 1 1 1 1 Rad51 DnaB_C PF03796.10 CCD22519.1 - 0.0058 15.5 0.0 0.0095 14.8 0.0 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Bys1 PF04681.7 CCD22519.1 - 0.032 13.9 0.1 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Blastomyces yeast-phase-specific protein Glyco_transf_20 PF00982.16 CCD22520.1 - 6.2e-149 496.4 0.6 1e-148 495.7 0.4 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCD22520.1 - 5e-84 280.8 0.0 9.2e-84 280.0 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase FliE PF02049.13 CCD22521.1 - 7.2 6.7 8.0 4.8 7.2 1.0 2.7 1 1 2 3 3 3 0 Flagellar hook-basal body complex protein FliE PAP2 PF01569.16 CCD22522.1 - 4.4e-08 32.8 8.3 1e-06 28.4 5.7 2.6 1 1 0 1 1 1 1 PAP2 superfamily Acetyltransf_1 PF00583.19 CCD22523.1 - 3.3e-09 36.6 0.0 5.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCD22523.1 - 2.4e-08 34.0 0.0 3.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCD22523.1 - 0.0022 17.8 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCD22523.1 - 0.017 15.2 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCD22523.1 - 0.024 14.5 0.0 0.17 11.7 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCD22523.1 - 0.042 13.8 0.1 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MEF2_binding PF09047.5 CCD22524.1 - 0.016 14.8 0.1 0.031 13.9 0.1 1.5 1 0 0 1 1 1 0 MEF2 binding UCH PF00443.24 CCD22525.1 - 1.7e-63 214.2 2.4 1.7e-63 214.2 1.6 3.7 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCD22525.1 - 1.5e-27 96.8 1.9 1.5e-27 96.8 1.3 4.0 4 1 1 5 5 5 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 CCD22525.1 - 4.5e-07 30.2 0.1 1.8e-06 28.2 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Zn-ribbon_8 PF09723.5 CCD22525.1 - 0.24 11.3 1.5 1.8 8.5 0.2 2.5 2 0 0 2 2 2 0 Zinc ribbon domain BSD PF03909.12 CCD22526.1 - 7.6e-14 51.1 0.4 2.6e-13 49.5 0.2 2.0 1 0 0 1 1 1 1 BSD domain Y_phosphatase2 PF03162.8 CCD22527.1 - 2.6e-52 176.5 3.1 3.5e-51 172.8 2.2 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCD22527.1 - 0.0033 17.6 0.0 0.0093 16.2 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CCD22527.1 - 0.018 14.6 5.1 0.67 9.5 1.1 3.1 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain YqcI_YcgG PF08892.6 CCD22527.1 - 0.032 13.7 0.1 0.049 13.1 0.0 1.2 1 0 0 1 1 1 0 YqcI/YcgG family NAD_binding_6 PF08030.7 CCD22527.1 - 0.17 11.7 4.5 0.11 12.4 1.2 1.8 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Topoisom_I_N PF02919.10 CCD22527.1 - 1.6 7.9 7.3 5.4 6.2 1.4 2.1 2 0 0 2 2 2 0 Eukaryotic DNA topoisomerase I, DNA binding fragment RPAP2_Rtr1 PF04181.8 CCD22528.1 - 1.4e-11 44.2 0.0 2.5e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family Caps_synth_GfcC PF06251.6 CCD22529.1 - 0.041 13.0 2.7 0.069 12.3 1.6 1.6 2 0 0 2 2 2 0 Capsule biosynthesis GfcC Cofilin_ADF PF00241.15 CCD22530.1 - 2.4e-07 30.6 0.0 2.8e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Aminotran_1_2 PF00155.16 CCD22531.1 - 6.2e-68 229.3 0.0 7.5e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II OKR_DC_1 PF01276.15 CCD22531.1 - 0.011 14.2 0.0 0.024 13.1 0.0 1.4 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain DUF3450 PF11932.3 CCD22531.1 - 0.087 12.0 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ABC_tran PF00005.22 CCD22532.1 - 1.3e-23 83.7 1.0 4.3e-14 52.9 0.0 3.0 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 CCD22532.1 - 2.3e-05 24.5 14.9 0.0005 20.1 0.3 3.9 3 2 1 4 4 4 2 AAA domain AAA_23 PF13476.1 CCD22532.1 - 0.0001 22.7 0.3 0.15 12.4 0.1 3.3 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CCD22532.1 - 0.0025 17.2 0.0 0.0047 16.4 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 CCD22532.1 - 0.016 15.0 0.1 4.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 CCD22532.1 - 0.029 13.2 0.0 0.049 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 CCD22532.1 - 0.038 14.1 0.0 3.6 7.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 CCD22532.1 - 0.072 13.5 0.0 0.2 12.1 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 CCD22532.1 - 0.13 11.6 0.3 0.3 10.5 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LSM PF01423.17 CCD22533.1 - 1.4e-16 59.7 0.3 2e-16 59.2 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCD22533.1 - 0.1 12.5 0.1 0.13 12.2 0.0 1.3 1 1 0 1 1 1 0 Ataxin 2 SM domain zf-CCHC_4 PF14392.1 CCD22534.1 - 0.28 10.8 3.1 0.6 9.8 1.6 1.9 2 0 0 2 2 2 0 Zinc knuckle Cep57_MT_bd PF06657.8 CCD22534.1 - 0.42 10.5 2.9 0.24 11.3 0.4 1.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 dUTPase PF00692.14 CCD22535.1 - 1.4e-41 140.9 0.0 1.7e-41 140.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase Mog1 PF04603.7 CCD22536.1 - 6.1e-18 65.1 0.5 2e-15 56.9 0.4 2.8 1 1 0 1 1 1 1 Ran-interacting Mog1 protein DUF3439 PF11921.3 CCD22536.1 - 0.0073 16.0 4.9 0.016 14.9 3.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Gly_transf_sug PF04488.10 CCD22537.1 - 1.5e-12 47.7 0.9 9.5e-12 45.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3450 PF11932.3 CCD22537.1 - 0.0053 16.0 0.6 0.0075 15.5 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF3373 PF11853.3 CCD22537.1 - 0.048 12.1 0.1 0.058 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Mating_N PF12731.2 CCD22537.1 - 0.071 12.9 0.3 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 Mating-type protein beta 1 UPF0118 PF01594.11 CCD22537.1 - 0.076 11.9 2.5 0.12 11.3 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 Peptidase_S49_N PF08496.5 CCD22537.1 - 0.4 10.4 6.5 0.68 9.7 4.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1514 PF07438.6 CCD22537.1 - 0.5 10.3 7.1 0.24 11.3 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) Syja_N PF02383.13 CCD22538.1 - 1e-84 284.0 5.2 1.7e-84 283.3 3.6 1.3 1 0 0 1 1 1 1 SacI homology domain Flavodoxin_2 PF02525.12 CCD22539.1 - 4.1e-50 170.0 0.0 5.8e-50 169.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCD22539.1 - 1.2e-12 47.5 0.0 3.5e-12 46.0 0.0 1.7 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CCD22539.1 - 1.6e-05 24.2 0.1 3.4e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 Flavodoxin Mito_carr PF00153.22 CCD22540.1 - 1.1e-47 159.7 6.7 9.2e-19 66.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S2 PF00318.15 CCD22541.1 - 8.6e-60 201.5 0.0 1.5e-59 200.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S2 Ribosomal_L10 PF00466.15 CCD22543.1 - 1.7e-20 72.8 0.2 2.5e-20 72.2 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 DUF3538 PF12057.3 CCD22543.1 - 0.064 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3538) Pkinase PF00069.20 CCD22544.1 - 5.9e-69 232.1 0.0 1.2e-68 231.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22544.1 - 8e-46 156.2 0.0 1.7e-45 155.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CCD22544.1 - 2.8e-16 59.6 0.7 1.4e-15 57.4 0.1 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 CCD22544.1 - 0.00053 19.0 0.0 0.0014 17.6 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCD22544.1 - 0.17 11.5 0.1 0.43 10.2 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Flavodoxin_2 PF02525.12 CCD22545.1 - 3.1e-54 183.5 0.0 4e-54 183.1 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCD22545.1 - 1.8e-12 47.0 0.0 5.4e-12 45.4 0.0 1.8 2 1 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CCD22545.1 - 4e-05 23.0 0.2 8.4e-05 21.9 0.2 1.8 1 1 0 1 1 1 1 Flavodoxin SRP1_TIP1 PF00660.12 CCD22546.1 - 9.6e-38 128.1 0.8 9.6e-38 128.1 0.5 1.8 2 1 0 2 2 2 1 Seripauperin and TIP1 family PAP1 PF08601.5 CCD22546.1 - 7.4 6.1 11.9 9.7 5.7 8.3 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 PEMT PF04191.8 CCD22547.1 - 4.7e-34 116.6 3.3 4.7e-34 116.6 2.3 1.8 2 1 0 2 2 2 1 Phospholipid methyltransferase DUF1673 PF07895.6 CCD22547.1 - 0.039 13.4 1.0 0.066 12.7 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) PAC2 PF09754.4 CCD22548.1 - 2e-26 93.2 0.0 4.4e-26 92.0 0.0 1.5 1 1 0 1 1 1 1 PAC2 family AAA PF00004.24 CCD22551.1 - 8e-17 61.6 0.0 1.6e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CCD22551.1 - 2.3e-14 53.3 0.0 1.2e-13 51.0 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CCD22551.1 - 4.2e-13 49.0 0.0 8.2e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 CCD22551.1 - 6.4e-11 41.6 0.1 4e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CCD22551.1 - 1.5e-06 28.3 0.0 1.2e-05 25.4 0.0 2.3 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CCD22551.1 - 2e-06 27.0 0.0 4e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCD22551.1 - 1.3e-05 24.7 0.0 3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CCD22551.1 - 1.4e-05 24.9 0.0 4.4e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCD22551.1 - 2e-05 24.2 0.0 3.4e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCD22551.1 - 0.00011 22.2 0.1 0.0015 18.5 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 CCD22551.1 - 0.00075 18.7 0.0 0.013 14.6 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CCD22551.1 - 0.00086 20.1 0.0 0.0034 18.1 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CCD22551.1 - 0.0024 17.5 0.3 0.0077 15.8 0.2 1.9 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCD22551.1 - 0.0024 17.4 0.0 0.0099 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 CCD22551.1 - 0.0033 16.3 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) DUF2075 PF09848.4 CCD22551.1 - 0.0057 15.6 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 CCD22551.1 - 0.0058 16.7 0.0 0.2 11.8 0.0 2.6 2 0 0 2 2 2 1 RNA helicase TIP49 PF06068.8 CCD22551.1 - 0.0063 15.2 0.0 0.13 11.0 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_23 PF13476.1 CCD22551.1 - 0.011 16.1 0.2 0.03 14.6 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCD22551.1 - 0.013 15.8 0.0 0.048 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CCD22551.1 - 0.014 15.1 0.3 0.12 12.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DNA_pol3_gamma3 PF12169.3 CCD22551.1 - 0.016 14.9 0.0 0.058 13.1 0.0 1.9 2 0 0 2 2 1 0 DNA polymerase III subunits gamma and tau domain III AAA_3 PF07726.6 CCD22551.1 - 0.022 14.3 0.0 0.19 11.3 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 CCD22551.1 - 0.022 14.2 0.0 0.053 12.9 0.0 1.6 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_25 PF13481.1 CCD22551.1 - 0.023 14.1 0.0 0.07 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CCD22551.1 - 0.027 14.1 0.3 0.37 10.4 0.0 2.6 1 1 0 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 CCD22551.1 - 0.036 14.0 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CCD22551.1 - 0.036 13.8 0.0 0.18 11.6 0.0 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCD22551.1 - 0.059 12.1 0.0 1.3 7.7 0.0 2.2 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_10 PF12846.2 CCD22551.1 - 0.07 12.5 0.0 0.2 11.0 0.0 2.1 1 1 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 CCD22551.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain Yae1_N PF09811.4 CCD22552.1 - 4.1e-12 45.4 0.0 6.8e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal FAT PF02259.18 CCD22553.1 - 6.5e-118 393.7 5.5 6.5e-118 393.7 3.8 2.2 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 CCD22553.1 - 2e-58 197.6 0.4 5.1e-58 196.3 0.3 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 CCD22553.1 - 1.2e-54 184.5 1.3 1.2e-54 184.5 0.9 4.3 4 0 0 4 4 4 2 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 CCD22553.1 - 3.9e-38 129.5 7.2 9.8e-38 128.2 2.2 3.1 2 0 0 2 2 2 1 Rapamycin binding domain FATC PF02260.15 CCD22553.1 - 6e-17 60.7 0.1 1.4e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 CCD22553.1 - 3.5e-13 49.6 6.4 0.00027 21.1 0.0 7.3 7 1 0 8 8 8 3 HEAT repeats HEAT PF02985.17 CCD22553.1 - 2e-10 39.8 2.0 0.36 11.0 0.0 8.6 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 CCD22553.1 - 7.9e-06 26.2 10.5 0.023 15.1 0.0 8.6 10 1 1 11 11 11 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CCD22553.1 - 0.037 14.4 16.8 1.3 9.4 0.0 6.0 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region Actin PF00022.14 CCD22554.1 - 3e-92 309.0 0.0 8.2e-92 307.6 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCD22554.1 - 1.7e-05 23.6 0.0 0.0061 15.1 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Cpn60_TCP1 PF00118.19 CCD22555.1 - 6.7e-141 470.2 4.4 7.7e-141 470.0 3.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CPT PF07931.7 CCD22555.1 - 0.0074 15.9 1.3 2.3 7.8 0.0 2.9 2 1 0 2 2 2 2 Chloramphenicol phosphotransferase-like protein TFIIS_C PF01096.13 CCD22556.1 - 4.7e-19 67.7 1.2 4.7e-19 67.7 0.8 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CCD22556.1 - 3.2e-12 45.9 9.6 1.8e-09 37.1 0.8 3.1 2 1 0 2 2 2 2 RNA polymerases M/15 Kd subunit Lar_restr_allev PF14354.1 CCD22556.1 - 8.7e-06 25.9 5.5 0.00059 20.0 0.3 2.6 2 1 0 2 2 2 1 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 CCD22556.1 - 0.00013 21.0 9.5 1.4 8.2 0.1 4.3 4 0 0 4 4 4 1 zinc-ribbon domain DZR PF12773.2 CCD22556.1 - 0.00031 20.5 7.3 0.037 13.8 0.2 2.9 2 1 1 3 3 3 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 CCD22556.1 - 0.001 18.5 15.7 0.32 10.5 0.8 4.4 3 2 1 4 4 4 2 zinc-ribbon domain Zn-ribbon_8 PF09723.5 CCD22556.1 - 0.0016 18.3 12.5 0.11 12.4 0.6 3.3 3 0 0 3 3 3 1 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CCD22556.1 - 0.003 17.3 4.4 0.0064 16.2 0.2 2.5 2 1 0 2 2 2 1 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 CCD22556.1 - 0.014 14.9 11.1 0.82 9.3 0.5 3.5 3 0 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 CCD22556.1 - 0.015 14.6 2.7 0.015 14.6 1.9 3.0 2 2 0 2 2 2 0 TFIIB zinc-binding zf-TFIIB PF13453.1 CCD22556.1 - 0.015 14.4 4.6 0.021 13.9 0.6 2.4 2 0 0 2 2 2 0 Transcription factor zinc-finger zf-DNA_Pol PF08996.5 CCD22556.1 - 0.015 14.6 4.9 0.21 10.9 0.6 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Mu-like_Com PF10122.4 CCD22556.1 - 0.03 13.3 0.2 3.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Mu-like prophage protein Com Elf1 PF05129.8 CCD22556.1 - 0.035 13.7 4.8 0.34 10.6 0.5 2.4 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like DUF2387 PF09526.5 CCD22556.1 - 0.037 13.9 0.2 0.037 13.9 0.1 2.6 2 1 1 3 3 3 0 Probable metal-binding protein (DUF2387) zf-C4_Topoisom PF01396.14 CCD22556.1 - 0.039 13.4 2.0 0.039 13.4 1.4 3.2 3 1 0 3 3 2 0 Topoisomerase DNA binding C4 zinc finger DUF2072 PF09845.4 CCD22556.1 - 0.042 13.7 6.1 0.049 13.5 0.1 2.9 1 1 2 3 3 3 0 Zn-ribbon containing protein (DUF2072) zf-H2C2_2 PF13465.1 CCD22556.1 - 0.046 14.0 6.0 0.46 10.8 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger double domain DUF523 PF04463.7 CCD22556.1 - 0.06 13.1 0.2 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF523) Baculo_LEF5_C PF11792.3 CCD22556.1 - 0.066 12.6 0.0 0.066 12.6 0.0 2.6 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zf-C3HC4_3 PF13920.1 CCD22556.1 - 0.069 12.8 3.5 2.8 7.6 0.1 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Terminase_GpA PF05876.7 CCD22556.1 - 0.073 11.4 1.5 0.091 11.0 0.4 1.6 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) zinc_ribbon_4 PF13717.1 CCD22556.1 - 0.082 12.6 14.2 0.68 9.6 0.5 3.5 4 0 0 4 4 3 0 zinc-ribbon domain Ogr_Delta PF04606.7 CCD22556.1 - 0.12 12.0 7.6 0.086 12.5 1.6 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger C1_1 PF00130.17 CCD22556.1 - 0.26 11.0 4.3 1.7 8.4 0.1 2.5 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Rubredoxin PF00301.15 CCD22556.1 - 0.4 10.6 7.8 10 6.1 0.2 3.6 4 0 0 4 4 4 0 Rubredoxin CpXC PF14353.1 CCD22556.1 - 0.44 10.4 7.7 2.6 7.9 0.1 3.1 1 1 2 3 3 3 0 CpXC protein HypA PF01155.14 CCD22556.1 - 0.57 9.8 8.4 2.5 7.7 2.0 3.0 1 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family Stc1 PF12898.2 CCD22556.1 - 0.59 10.2 7.2 0.23 11.5 0.7 2.3 1 1 1 2 2 2 0 Stc1 domain OrfB_Zn_ribbon PF07282.6 CCD22556.1 - 1 9.0 8.0 12 5.6 0.2 2.8 2 1 0 2 2 2 0 Putative transposase DNA-binding domain RRN7 PF11781.3 CCD22556.1 - 1.1 8.7 10.9 19 4.8 0.0 3.8 3 1 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-C2H2_4 PF13894.1 CCD22556.1 - 1.2 9.6 8.0 27 5.3 1.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger GATA PF00320.22 CCD22556.1 - 1.3 8.4 8.2 0.57 9.5 1.0 2.9 3 0 0 3 3 3 0 GATA zinc finger zf-CHY PF05495.7 CCD22556.1 - 1.4 9.1 7.5 3.8 7.7 0.1 2.9 2 1 1 3 3 3 0 CHY zinc finger PolC_DP2 PF03833.8 CCD22556.1 - 1.8 6.0 4.8 0.43 8.1 0.5 1.7 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 DUF983 PF06170.7 CCD22556.1 - 2.5 8.2 4.0 71 3.6 1.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF983) zf-AN1 PF01428.11 CCD22556.1 - 3.5 7.5 9.2 35 4.3 0.1 3.5 3 1 0 3 3 3 0 AN1-like Zinc finger zf-ISL3 PF14690.1 CCD22556.1 - 6.9 6.7 9.6 0.84 9.7 0.2 3.1 4 0 0 4 4 3 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 YhfH PF14149.1 CCD22556.1 - 7.2 6.5 10.7 14 5.5 0.4 3.5 3 1 0 3 3 3 0 YhfH-like protein NOB1_Zn_bind PF08772.6 CCD22556.1 - 8.3 6.3 10.2 5.5 6.8 1.2 3.3 2 2 1 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like C1_4 PF07975.7 CCD22556.1 - 8.9 6.4 16.5 31 4.6 4.0 3.8 2 2 2 4 4 4 0 TFIIH C1-like domain PRCC PF10253.4 CCD22557.1 - 0.00041 21.1 0.7 0.00048 20.8 0.5 1.2 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting CN_hydrolase PF00795.17 CCD22558.1 - 9.3e-14 51.1 0.0 1.7e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LicD PF04991.8 CCD22559.1 - 4e-49 167.5 2.3 4e-49 167.5 1.6 2.7 2 0 0 2 2 2 1 LicD family DUF1342 PF07072.6 CCD22559.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1342) HLH PF00010.21 CCD22560.1 - 4.5e-13 48.6 1.8 1.1e-12 47.3 1.2 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 CCD22561.1 - 7.1e-40 136.7 0.0 1.2e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22561.1 - 2.5e-13 49.6 0.0 4.8e-13 48.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCD22561.1 - 0.0011 18.0 0.0 0.0019 17.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCD22561.1 - 0.04 12.8 0.0 0.069 12.1 0.0 1.3 1 0 0 1 1 1 0 Kinase-like MU117 PF15474.1 CCD22562.1 - 0.055 13.9 1.8 0.14 12.6 0.6 2.1 2 1 0 2 2 2 0 Meiotically up-regulated gene family DUF968 PF06147.6 CCD22562.1 - 0.066 13.1 0.4 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF968) rve PF00665.21 CCD22563.1 - 3.3e-19 69.1 0.0 9.6e-19 67.6 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CCD22563.1 - 2.7e-12 46.5 1.3 4.7e-12 45.7 0.1 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 CCD22563.1 - 0.00018 21.3 0.5 0.00076 19.3 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CCD22563.1 - 0.00096 18.9 0.0 0.0029 17.3 0.0 1.8 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CCD22563.1 - 0.023 15.1 0.0 0.093 13.2 0.0 2.2 2 0 0 2 2 2 0 Aspartyl protease Peptidase_A2B PF12384.3 CCD22563.1 - 0.4 9.9 5.4 0.18 11.0 0.1 2.9 4 0 0 4 4 4 0 Ty3 transposon peptidase RRM_5 PF13893.1 CCD22564.1 - 2.8e-13 49.5 0.4 1.4e-12 47.2 0.0 2.0 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCD22564.1 - 1.9e-08 33.8 0.2 4.7e-08 32.5 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD22564.1 - 4.3e-07 29.8 0.0 9.9e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) IMS PF00817.15 CCD22565.1 - 1.4e-44 151.4 0.0 2.5e-44 150.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 CCD22565.1 - 1.6e-05 24.8 0.1 3.5e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CCD22565.1 - 4.7e-05 23.1 0.0 0.00015 21.6 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2_4 PF13894.1 CCD22565.1 - 0.14 12.5 0.9 0.36 11.2 0.6 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DUF1805 PF08827.6 CCD22565.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) Ribosomal_L11_N PF03946.9 CCD22566.1 - 1.5e-17 62.7 0.8 3.8e-17 61.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CCD22566.1 - 1.1e-11 44.6 1.6 1.7e-11 44.1 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain TPR_11 PF13414.1 CCD22567.1 - 4.8e-08 32.5 1.9 0.19 11.4 0.0 5.5 5 0 0 5 5 5 1 TPR repeat TPR_14 PF13428.1 CCD22567.1 - 2e-07 31.0 0.0 0.069 13.8 0.0 6.7 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCD22567.1 - 3.2e-07 30.1 0.9 0.032 14.1 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCD22567.1 - 5.8e-06 26.5 0.4 6.7 7.1 0.0 5.2 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCD22567.1 - 2.6e-05 23.8 2.8 0.083 12.8 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCD22567.1 - 0.00027 21.4 0.0 0.63 10.7 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCD22567.1 - 0.00047 19.7 6.8 0.87 9.5 0.0 5.6 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 CCD22567.1 - 0.00091 18.9 2.3 0.79 9.5 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCD22567.1 - 0.0016 18.0 0.1 0.0016 18.0 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CCD22567.1 - 0.0099 15.9 6.3 0.65 10.1 0.3 4.3 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCD22567.1 - 0.071 13.6 1.6 23 5.7 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCD22567.1 - 0.13 11.9 5.0 4.3 7.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat HAT PF02184.11 CCD22567.1 - 1.6 8.5 6.9 25 4.7 0.0 4.8 6 0 0 6 6 5 0 HAT (Half-A-TPR) repeat TPR_10 PF13374.1 CCD22567.1 - 1.7 8.7 3.6 5.8 6.9 0.0 3.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ATP-synt_D PF01813.12 CCD22568.1 - 2.5e-64 216.4 4.1 3.8e-64 215.8 2.8 1.3 1 0 0 1 1 1 1 ATP synthase subunit D HET PF06985.6 CCD22568.1 - 1.2 9.2 3.7 1.8 8.7 1.0 2.4 2 1 0 2 2 2 0 Heterokaryon incompatibility protein (HET) Ribosomal_L6e PF01159.14 CCD22568.1 - 2.2 8.5 7.2 1.2 9.3 3.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L6e Viral_P18 PF04521.8 CCD22568.1 - 9.8 5.6 8.6 5.1 6.5 0.2 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Peptidase_M28 PF04389.12 CCD22569.1 - 2.7e-23 82.6 0.0 6.4e-23 81.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 CCD22569.1 - 0.00053 19.5 0.0 0.00069 19.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 EXS PF03124.9 CCD22570.1 - 4.8e-58 196.8 25.2 5.7e-58 196.5 17.4 1.0 1 0 0 1 1 1 1 EXS family DUF412 PF04217.8 CCD22570.1 - 0.1 12.3 1.3 0.74 9.6 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF412 Nop25 PF09805.4 CCD22571.1 - 5.6e-39 133.3 20.1 5.6e-39 133.3 13.9 2.3 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) AAA_21 PF13304.1 CCD22571.1 - 4.2 7.2 16.2 0.51 10.2 1.8 2.1 1 1 1 2 2 2 0 AAA domain DER1 PF04511.10 CCD22572.1 - 1.1e-38 132.7 6.6 1.4e-38 132.3 4.6 1.1 1 0 0 1 1 1 1 Der1-like family Tub PF01167.13 CCD22572.1 - 0.082 11.8 0.1 0.16 10.9 0.1 1.4 1 0 0 1 1 1 0 Tub family DUF2681 PF10883.3 CCD22572.1 - 3.5 7.9 5.9 8.2 6.7 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) ICMT PF04140.9 CCD22573.1 - 1.3e-29 102.2 0.2 2.1e-29 101.5 0.2 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCD22573.1 - 1.2e-15 57.4 6.2 2.9e-15 56.2 0.6 2.8 3 0 0 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 CCD22573.1 - 9.5e-05 21.8 0.3 0.00013 21.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) HXXEE PF13787.1 CCD22573.1 - 0.028 14.7 0.0 0.028 14.7 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function with HXXEE motif NnrU PF07298.6 CCD22573.1 - 0.045 13.1 0.2 0.13 11.6 0.1 1.7 1 1 0 1 1 1 0 NnrU protein PINIT PF14324.1 CCD22574.1 - 1.3e-38 132.3 0.3 3e-38 131.1 0.2 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 CCD22574.1 - 2.3e-19 68.6 8.4 4.6e-19 67.6 5.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CCD22574.1 - 0.00041 19.8 0.8 0.00099 18.5 0.6 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CCD22574.1 - 0.011 15.4 0.5 0.025 14.3 0.1 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CCD22574.1 - 1.5 8.9 4.1 2.9 8.0 2.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4613 PF15390.1 CCD22574.1 - 2 6.4 9.3 3.2 5.8 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) Formyl_trans_N PF00551.14 CCD22575.1 - 8.6e-50 168.7 0.0 1e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.13 CCD22575.1 - 0.096 12.2 0.2 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase TRAPPC9-Trs120 PF08626.6 CCD22576.1 - 0 1028.5 26.7 0 1028.0 18.5 1.2 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit ABC2_membrane PF01061.19 CCD22577.1 - 3.5e-88 294.2 51.8 1.1e-45 155.4 15.6 2.4 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 CCD22577.1 - 1.3e-42 143.6 0.6 9.1e-38 128.0 0.0 3.1 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 CCD22577.1 - 1.5e-38 132.1 0.1 1.5e-17 64.2 0.0 3.4 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 CCD22577.1 - 2.4e-19 69.1 1.8 4.2e-19 68.4 0.1 2.3 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CCD22577.1 - 4.8e-08 32.6 0.1 7.9e-05 22.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 CCD22577.1 - 3.7e-06 26.2 33.5 0.00092 18.3 7.1 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 CCD22577.1 - 3.8e-06 27.0 0.7 0.00027 20.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CCD22577.1 - 2.5e-05 24.5 0.2 0.1 12.9 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CCD22577.1 - 3.4e-05 23.0 0.0 0.0022 17.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 CCD22577.1 - 0.00026 20.6 0.3 0.52 10.0 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain cobW PF02492.14 CCD22577.1 - 0.0004 19.8 2.1 0.1 12.0 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CCD22577.1 - 0.00067 19.1 1.8 0.005 16.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 CCD22577.1 - 0.00069 19.6 0.6 0.11 12.4 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCD22577.1 - 0.0009 19.1 0.0 0.098 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CCD22577.1 - 0.00091 19.5 0.2 0.11 12.8 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CCD22577.1 - 0.0015 18.7 0.5 0.64 10.1 0.0 3.3 3 0 0 3 3 2 1 AAA domain SMC_N PF02463.14 CCD22577.1 - 0.0015 17.8 0.0 0.16 11.1 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 CCD22577.1 - 0.0027 17.3 0.6 2.5 7.7 0.1 2.7 2 0 0 2 2 2 2 NACHT domain UPF0079 PF02367.12 CCD22577.1 - 0.0037 16.8 0.8 0.77 9.3 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 CCD22577.1 - 0.005 17.6 0.0 1.3 9.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CCD22577.1 - 0.011 15.6 0.0 0.19 11.6 0.0 2.8 2 0 0 2 2 2 0 AAA domain OCD_Mu_crystall PF02423.10 CCD22577.1 - 0.065 11.9 0.0 2.1 7.0 0.0 2.5 2 1 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family PduV-EutP PF10662.4 CCD22577.1 - 0.075 12.5 0.3 1.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CCD22577.1 - 0.092 12.9 0.1 19 5.4 0.0 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCD22577.1 - 0.15 11.7 0.0 23 4.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 CCD22577.1 - 0.77 9.3 4.9 6.7 6.2 0.2 2.7 3 0 0 3 3 2 0 AAA domain Ribosomal_L23 PF00276.15 CCD22579.1 - 2.5e-21 75.4 0.0 5.4e-21 74.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 SHS2_Rpb7-N PF03876.12 CCD22580.1 - 3.6e-16 59.0 0.0 6.9e-16 58.1 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CCD22580.1 - 1e-15 57.5 0.1 1.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 CCD22580.1 - 4.1e-06 26.9 0.0 7.3e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 DIT1_PvcA PF05141.7 CCD22581.1 - 3.5e-101 338.1 0.0 4.8e-101 337.7 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein p450 PF00067.17 CCD22582.1 - 3.5e-43 147.8 0.2 4.6e-43 147.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 IU_nuc_hydro PF01156.14 CCD22583.1 - 2.9e-75 253.4 0.0 3.3e-75 253.2 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Pribosyltran PF00156.22 CCD22584.1 - 2.4e-11 43.4 0.0 4.9e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Fe-ADH PF00465.14 CCD22584.1 - 0.059 11.9 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase 3Beta_HSD PF01073.14 CCD22584.1 - 0.075 11.7 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Apolipo_F PF15148.1 CCD22584.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Apolipoprotein F Mito_fiss_Elm1 PF06258.6 CCD22584.1 - 0.16 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 IBN_N PF03810.14 CCD22585.1 - 2.7e-16 59.2 0.2 1.5e-15 56.8 0.1 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain AAA PF00004.24 CCD22586.1 - 2.8e-46 156.9 0.0 8.3e-46 155.4 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCD22586.1 - 2.9e-08 33.8 0.0 6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCD22586.1 - 3.4e-08 33.2 0.1 1.4e-07 31.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCD22586.1 - 6e-07 29.6 0.1 2.6e-06 27.5 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCD22586.1 - 1.2e-06 28.7 1.8 8.5e-05 22.7 0.3 3.1 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.8 CCD22586.1 - 5.3e-05 22.2 0.0 9e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 CCD22586.1 - 8.7e-05 22.4 0.0 0.00068 19.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCD22586.1 - 0.0002 22.1 0.1 0.00063 20.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CCD22586.1 - 0.00062 18.8 0.0 0.0014 17.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 CCD22586.1 - 0.0011 18.7 0.0 0.0029 17.3 0.0 1.8 1 0 0 1 1 1 1 NTPase AAA_19 PF13245.1 CCD22586.1 - 0.0015 18.2 0.1 0.0037 16.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 CCD22586.1 - 0.0015 18.6 0.0 0.0033 17.5 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 CCD22586.1 - 0.0018 17.3 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_11 PF13086.1 CCD22586.1 - 0.002 17.7 0.0 0.0087 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CCD22586.1 - 0.002 17.7 0.0 0.0075 15.8 0.0 2.0 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CCD22586.1 - 0.0033 17.3 0.0 0.0075 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CCD22586.1 - 0.0034 16.9 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCD22586.1 - 0.0037 16.6 0.8 0.11 11.9 0.1 2.4 1 1 1 2 2 2 1 AAA domain TIP49 PF06068.8 CCD22586.1 - 0.0038 16.0 0.0 0.0066 15.2 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus AAA_28 PF13521.1 CCD22586.1 - 0.0039 17.1 0.0 0.0089 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CCD22586.1 - 0.004 16.8 0.5 0.061 12.9 0.0 2.6 2 1 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.21 CCD22586.1 - 0.0058 16.1 0.0 0.18 11.2 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 CCD22586.1 - 0.006 15.7 0.1 0.016 14.3 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 CCD22586.1 - 0.0067 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 CCD22586.1 - 0.0096 15.5 0.0 0.022 14.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCD22586.1 - 0.013 15.8 0.0 0.045 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CCD22586.1 - 0.014 15.1 0.6 0.13 11.9 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase IstB_IS21 PF01695.12 CCD22586.1 - 0.014 14.7 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 CCD22586.1 - 0.042 14.1 1.4 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 CCD22586.1 - 0.074 12.6 0.0 0.19 11.3 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein NB-ARC PF00931.17 CCD22586.1 - 0.087 11.6 0.0 0.18 10.6 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain She9_MDM33 PF05546.6 CCD22587.1 - 1.3e-91 305.8 26.7 1.4e-91 305.6 9.7 2.3 2 1 0 2 2 2 2 She9 / Mdm33 family Peptidase_C12 PF01088.16 CCD22587.1 - 0.0066 15.6 3.5 0.0066 15.6 2.5 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 PsbH PF00737.15 CCD22587.1 - 0.15 11.6 0.4 0.28 10.7 0.3 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein KH_1 PF00013.24 CCD22588.1 - 0.00038 20.0 0.4 0.00093 18.7 0.3 1.6 1 0 0 1 1 1 1 KH domain TFIID-18kDa PF02269.11 CCD22589.1 - 1.6e-37 127.1 0.2 1.4e-36 124.1 0.0 2.3 2 0 0 2 2 2 1 Transcription initiation factor IID, 18kD subunit ThiF PF00899.16 CCD22590.1 - 2.9e-34 117.8 0.0 5.2e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CCD22590.1 - 1.3e-25 88.7 0.6 4.6e-25 86.9 0.4 2.0 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCD22590.1 - 1.8e-21 75.2 3.6 9.9e-21 72.8 2.8 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Tbf5 PF06331.7 CCD22590.1 - 0.0012 18.6 0.1 0.004 16.9 0.0 1.9 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 UAE_UbL PF14732.1 CCD22590.1 - 0.0073 16.3 0.7 0.017 15.2 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 CCD22590.1 - 0.021 14.8 0.0 0.07 13.2 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CCD22590.1 - 0.063 13.5 0.0 0.27 11.4 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding RhoGAP PF00620.22 CCD22591.1 - 9.4e-31 106.4 0.2 2.5e-19 69.3 0.0 3.1 3 0 0 3 3 3 2 RhoGAP domain BAR PF03114.13 CCD22592.1 - 1.1e-61 208.2 6.6 1.4e-61 207.9 4.6 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 CCD22592.1 - 8.8e-15 53.8 0.1 1.5e-14 53.0 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCD22592.1 - 8.3e-14 50.9 0.1 1.4e-13 50.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCD22592.1 - 7.7e-09 34.9 0.0 1.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF755 PF05501.6 CCD22592.1 - 0.053 13.5 0.9 0.12 12.3 0.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Sugar_tr PF00083.19 CCD22593.1 - 2.2e-97 326.4 26.9 4.2e-52 177.2 5.7 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCD22593.1 - 1.1e-32 113.1 42.3 1.7e-28 99.3 14.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCD22593.1 - 3.2e-07 29.1 5.1 3.2e-07 29.1 3.5 3.5 3 1 1 4 4 4 2 MFS/sugar transport protein Phage_holin_2 PF04550.7 CCD22593.1 - 1.5 8.9 8.0 0.6 10.2 1.4 3.1 3 0 0 3 3 3 0 Phage holin family 2 ERCC4 PF02732.10 CCD22594.1 - 3.1e-21 75.6 0.2 6.9e-21 74.5 0.2 1.6 1 0 0 1 1 1 1 ERCC4 domain HHH_3 PF12836.2 CCD22594.1 - 0.0061 16.4 0.1 0.022 14.6 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif rve PF00665.21 CCD22595.1 - 6.2e-20 71.4 0.0 1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain GTP_EFTU PF00009.22 CCD22596.1 - 2e-63 213.2 0.2 2.9e-63 212.7 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCD22596.1 - 9.3e-38 128.4 0.0 2.9e-37 126.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CCD22596.1 - 1.3e-21 76.2 0.0 3.5e-21 74.8 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CCD22596.1 - 2.9e-14 52.6 0.0 1.1e-13 50.8 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CCD22596.1 - 2.9e-12 46.5 0.5 2.6e-11 43.4 0.0 2.9 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCD22596.1 - 1.7e-05 24.7 0.1 3.6e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCD22596.1 - 0.099 13.1 0.2 0.41 11.1 0.1 2.1 2 0 0 2 2 2 0 Miro-like protein SUKH-4 PF14435.1 CCD22596.1 - 0.13 11.9 0.1 0.52 9.9 0.0 2.0 2 0 0 2 2 2 0 SUKH-4 immunity protein Grp1_Fun34_YaaH PF01184.14 CCD22597.1 - 5.2e-69 231.7 13.6 6.5e-69 231.4 9.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Mito_carr PF00153.22 CCD22598.1 - 3e-60 199.9 3.9 7e-20 70.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein TMEM141 PF15110.1 CCD22598.1 - 0.066 13.5 0.1 0.42 10.9 0.1 2.1 2 0 0 2 2 2 0 TMEM141 protein family RRM_1 PF00076.17 CCD22600.1 - 7.2e-12 44.7 0.0 1.3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD22600.1 - 1.1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD22600.1 - 0.00012 21.8 0.0 0.00019 21.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3154 PF11351.3 CCD22600.1 - 0.57 9.9 2.8 0.98 9.1 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) TPP_enzyme_C PF02775.16 CCD22601.1 - 1.2e-14 54.2 0.0 3e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCD22601.1 - 1.4e-14 53.9 0.0 2.9e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 CCD22601.1 - 2.2e-10 40.2 0.0 4.4e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Complex1_LYR PF05347.10 CCD22602.1 - 1.8e-13 50.0 0.7 2.1e-13 49.8 0.5 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCD22602.1 - 1.2e-12 47.8 0.7 1.4e-12 47.6 0.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like DUF816 PF05674.7 CCD22602.1 - 0.054 13.2 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) RhoGAP PF00620.22 CCD22603.1 - 4.2e-36 123.8 0.1 7.2e-36 123.0 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain LSM PF01423.17 CCD22604.1 - 8.4e-16 57.2 0.1 1e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCD22604.1 - 0.00059 19.7 0.0 0.0011 18.8 0.0 1.5 1 1 0 1 1 1 1 Ataxin 2 SM domain F1F0-ATPsyn_F PF10791.4 CCD22605.1 - 8.4e-39 131.7 0.2 9.4e-39 131.5 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 CCD22605.1 - 0.0011 18.9 0.1 0.0017 18.3 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f COX4_pro PF03626.9 CCD22605.1 - 0.09 12.8 0.0 0.095 12.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic Cytochrome C oxidase subunit IV NAD_binding_8 PF13450.1 CCD22606.1 - 8.6e-05 22.4 0.0 0.00036 20.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCD22606.1 - 0.00048 20.2 0.0 0.32 11.0 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCD22606.1 - 0.0017 18.1 0.0 0.0058 16.4 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCD22606.1 - 0.0017 18.2 0.0 0.0049 16.7 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CCD22606.1 - 0.017 15.2 0.0 3.3 7.8 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 CCD22606.1 - 0.033 13.0 0.0 0.66 8.7 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 CCD22606.1 - 0.049 12.5 0.0 0.079 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase DnaB_bind PF10410.4 CCD22607.1 - 0.025 14.5 0.2 0.09 12.7 0.0 1.9 2 0 0 2 2 2 0 DnaB-helicase binding domain of primase YTH PF04146.10 CCD22608.1 - 8e-43 145.3 1.5 1.3e-42 144.7 1.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain EVE PF01878.13 CCD22608.1 - 0.0018 18.3 0.1 0.021 14.8 0.0 2.2 2 0 0 2 2 2 1 EVE domain Ammonium_transp PF00909.16 CCD22609.1 - 1.5e-120 402.3 22.4 1.7e-120 402.1 15.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family ABC2_membrane_2 PF12679.2 CCD22609.1 - 6.1 5.6 12.9 0.24 10.2 3.9 2.1 2 1 0 2 2 2 0 ABC-2 family transporter protein WD40 PF00400.27 CCD22610.1 - 1e-21 75.9 1.3 3e-07 30.0 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3639 PF12341.3 CCD22611.1 - 5.9e-13 48.5 0.2 1.3e-12 47.4 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) WD40 PF00400.27 CCD22611.1 - 0.024 14.5 0.1 0.11 12.3 0.0 2.3 1 0 0 1 1 1 0 WD domain, G-beta repeat Med26 PF08711.6 CCD22613.1 - 6.2e-15 54.4 0.5 1.3e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Phasin PF05597.6 CCD22613.1 - 0.3 10.8 5.5 0.059 13.1 0.7 2.3 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Ribosom_S12_S23 PF00164.20 CCD22614.1 - 1.7e-40 137.2 0.6 2e-40 137.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acetyltransf_1 PF00583.19 CCD22615.1 - 3.8e-10 39.6 0.0 6e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCD22615.1 - 3.5e-05 23.4 0.0 7e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CCD22615.1 - 0.00037 20.5 0.0 0.00063 19.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCD22615.1 - 0.013 15.6 0.0 0.018 15.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCD22615.1 - 0.072 12.9 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mito_carr PF00153.22 CCD22616.1 - 8.6e-53 176.0 4.7 6.1e-19 67.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.16 CCD22617.1 - 6e-41 140.1 0.0 6.9e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LETM1 PF07766.8 CCD22618.1 - 5e-94 314.2 3.2 5e-94 314.2 2.2 1.5 2 0 0 2 2 2 1 LETM1-like protein RNA_pol_3_Rpc31 PF11705.3 CCD22618.1 - 9.6 6.0 16.1 9 6.1 0.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 SH2_2 PF14633.1 CCD22619.1 - 7.4e-104 345.6 3.8 7.4e-104 345.6 2.7 2.2 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.1 CCD22619.1 - 4.7e-64 214.4 0.1 1.4e-63 212.9 0.0 1.9 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 CCD22619.1 - 2.2e-50 169.5 4.6 2.2e-50 169.5 3.2 4.6 4 1 1 5 5 5 1 Death-like domain of SPT6 HHH_7 PF14635.1 CCD22619.1 - 3.9e-43 145.7 1.4 3.7e-42 142.6 0.1 3.1 3 0 0 3 3 3 1 Helix-hairpin-helix motif HTH_44 PF14641.1 CCD22619.1 - 2.3e-35 121.1 2.3 2.3e-35 121.1 1.6 3.6 5 0 0 5 5 5 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 CCD22619.1 - 5e-23 81.0 23.2 5e-23 81.0 16.1 5.8 5 1 2 7 7 7 1 Acidic N-terminal SPT6 SH2 PF00017.19 CCD22619.1 - 3e-12 46.1 0.2 1.1e-11 44.3 0.0 2.2 2 0 0 2 2 2 1 SH2 domain Ctr PF04145.10 CCD22620.1 - 5.3e-28 97.8 3.1 5.3e-28 97.8 2.2 2.1 2 0 0 2 2 2 1 Ctr copper transporter family Metallothio_2 PF01439.13 CCD22620.1 - 0.029 14.9 3.7 0.029 14.9 2.6 2.1 2 0 0 2 2 2 0 Metallothionein Peptidase_M16 PF00675.15 CCD22621.1 - 9.2e-33 113.0 0.0 2.6e-32 111.6 0.0 1.8 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCD22621.1 - 5.7e-14 52.2 1.1 4.2e-07 29.8 0.0 4.4 4 1 0 4 4 4 3 Peptidase M16 inactive domain Cyclin_N PF00134.18 CCD22622.1 - 5.3e-41 139.1 0.2 4.3e-40 136.2 0.1 2.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCD22622.1 - 6.9e-31 106.6 0.4 2.2e-30 104.9 0.0 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 CCD22623.1 - 6.2e-40 135.7 0.5 1.5e-38 131.2 0.1 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCD22623.1 - 2e-18 66.4 0.5 4.4e-18 65.3 0.1 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain IF-2B PF01008.12 CCD22624.1 - 5.1e-84 281.5 0.1 6.3e-84 281.2 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Peptidase_M15_4 PF13539.1 CCD22624.1 - 0.12 12.8 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Fmp27_WPPW PF10359.4 CCD22625.1 - 9.7e-126 419.9 4.2 1.8e-125 419.0 2.9 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 CCD22625.1 - 8.3e-100 334.7 0.8 8.3e-100 334.7 0.6 2.9 4 0 0 4 4 4 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 CCD22625.1 - 6.3e-47 159.3 0.3 2.3e-46 157.5 0.2 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CCD22625.1 - 4.5e-40 136.9 1.0 1.9e-39 134.9 0.7 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CCD22625.1 - 1.5e-20 73.5 0.4 1e-19 70.8 0.0 2.8 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain CPSase_L_D2 PF02786.12 CCD22626.1 - 0.011 15.0 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain PH PF00169.24 CCD22627.1 - 2.2e-09 37.4 1.2 2.2e-09 37.4 0.9 2.8 2 0 0 2 2 2 1 PH domain TRAM_LAG1_CLN8 PF03798.11 CCD22628.1 - 1.6e-31 109.4 17.1 1.6e-31 109.4 11.8 1.5 2 0 0 2 2 2 1 TLC domain PGA2 PF07543.7 CCD22628.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 DUF912 PF06024.7 CCD22628.1 - 0.7 9.9 0.0 0.7 9.9 0.0 2.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CDP-OH_P_transf PF01066.16 CCD22629.1 - 3.2e-18 65.8 3.4 6.6e-18 64.8 2.4 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase tRNA-synt_1 PF00133.17 CCD22630.1 - 1.5e-231 769.5 0.1 1.5e-231 769.5 0.1 2.1 2 1 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCD22630.1 - 2.9e-31 108.3 1.6 1.1e-30 106.4 1.1 2.1 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCD22630.1 - 1.8e-17 63.1 0.1 7.3e-09 34.7 0.1 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CCD22630.1 - 1.9e-07 30.5 0.0 1.9e-07 30.5 0.0 3.9 4 1 1 5 5 5 2 Leucyl-tRNA synthetase, Domain 2 PepSY PF03413.14 CCD22630.1 - 0.039 14.6 2.4 15 6.3 0.2 4.1 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain tRNA-synt_1e PF01406.14 CCD22630.1 - 0.51 9.4 9.3 1 8.4 0.0 3.7 4 1 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain RRM_1 PF00076.17 CCD22631.1 - 2.3e-67 222.5 13.9 1.2e-16 60.0 0.1 6.4 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD22631.1 - 3.4e-65 215.9 4.9 2.7e-15 56.0 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD22631.1 - 3.5e-38 129.2 0.3 5.2e-09 35.8 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCD22631.1 - 3.1e-06 26.8 0.0 0.89 9.3 0.0 4.6 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif DUF1699 PF08004.6 CCD22631.1 - 0.056 12.9 1.8 1.3 8.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) Pkinase PF00069.20 CCD22632.1 - 1.5e-52 178.2 0.2 4.8e-51 173.4 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22632.1 - 3e-26 92.0 0.2 3.8e-20 72.0 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCD22632.1 - 0.0011 18.0 0.1 0.0041 16.1 0.0 1.9 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 CCD22632.1 - 0.0036 17.0 0.0 0.042 13.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCD22632.1 - 0.049 12.6 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_pol_A_bac PF01000.21 CCD22633.1 - 1.8e-28 98.9 0.0 3.2e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CCD22633.1 - 2.8e-16 58.3 0.0 3.7e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1746 PF08508.5 CCD22634.1 - 0.021 14.7 2.2 1.3 9.0 0.1 3.0 3 0 0 3 3 3 0 Fungal domain of unknown function (DUF1746) RPN7 PF10602.4 CCD22635.1 - 4.5e-50 169.4 3.0 4.5e-50 169.4 2.1 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 CCD22635.1 - 5.6e-15 55.5 0.1 1.6e-14 54.1 0.1 1.8 1 0 0 1 1 1 1 PCI domain TPR_8 PF13181.1 CCD22635.1 - 0.0061 16.2 0.4 0.027 14.2 0.2 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF357 PF04010.8 CCD22635.1 - 0.0095 15.6 0.5 0.048 13.3 0.4 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF357) TPR_12 PF13424.1 CCD22635.1 - 0.019 14.8 1.0 1.5 8.7 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCCH PF00642.19 CCD22636.1 - 6.8e-11 41.5 28.5 0.0019 17.8 0.2 5.7 4 2 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CCD22636.1 - 5.8 7.0 30.9 1.2 9.2 0.5 5.8 5 1 0 5 5 5 0 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 CCD22637.1 - 1.1e-14 54.2 5.1 2.5e-14 53.0 3.5 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22637.1 - 9.5e-09 34.6 0.4 3.7e-08 32.7 0.3 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DRY_EERY PF09750.4 CCD22637.1 - 0.034 14.2 0.1 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Alternative splicing regulator HipA_N PF07805.7 CCD22637.1 - 0.097 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 HipA-like N-terminal domain Pil1 PF13805.1 CCD22638.1 - 2.7e-141 469.4 0.5 3.3e-141 469.1 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3295 PF11702.3 CCD22638.1 - 0.5 9.2 7.4 0.85 8.5 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF4446 PF14584.1 CCD22638.1 - 5.4 6.8 6.7 5.9 6.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) RNA_pol_3_Rpc31 PF11705.3 CCD22638.1 - 8.4 6.2 19.8 0.72 9.7 9.1 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 PBP1_TM PF14812.1 CCD22638.1 - 8.7 6.7 9.8 36 4.7 6.8 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal COG4 PF08318.7 CCD22639.1 - 6.3e-101 337.4 16.1 6.3e-101 337.4 11.1 2.0 2 0 0 2 2 2 1 COG4 transport protein Fork_head PF00250.13 CCD22640.1 - 4.2e-34 116.4 0.3 1.5e-33 114.6 0.2 2.0 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CCD22640.1 - 2e-12 47.0 0.3 8.4e-12 45.0 0.2 2.2 1 0 0 1 1 1 1 FHA domain Proteasome PF00227.21 CCD22641.1 - 1.2e-49 168.2 0.1 1.4e-49 167.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L5_C PF00673.16 CCD22642.1 - 1e-23 82.9 0.0 1.5e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CCD22642.1 - 5.6e-21 74.0 0.1 1.6e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 BCAS2 PF05700.6 CCD22643.1 - 0.003 17.0 13.7 0.12 11.7 9.5 2.2 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Ricin_B_lectin PF00652.17 CCD22643.1 - 0.038 14.0 0.2 0.057 13.4 0.2 1.2 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain APP_N PF02177.11 CCD22643.1 - 0.097 12.5 0.4 0.39 10.6 0.0 2.0 1 1 0 2 2 2 0 Amyloid A4 N-terminal heparin-binding L51_S25_CI-B8 PF05047.11 CCD22644.1 - 1e-12 47.5 0.3 1.9e-12 46.6 0.2 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain KID PF02524.9 CCD22644.1 - 0.051 13.6 3.8 1.4 9.3 0.6 2.9 2 0 0 2 2 2 0 KID repeat DUF4149 PF13664.1 CCD22645.1 - 1.2e-20 73.4 0.7 1.2e-20 73.4 0.5 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF4218 PF13960.1 CCD22645.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) MAS20 PF02064.10 CCD22646.1 - 2e-18 66.4 1.2 8.1e-18 64.4 0.8 1.8 1 1 0 1 1 1 1 MAS20 protein import receptor CD99L2 PF12301.3 CCD22646.1 - 0.0033 17.1 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 CD99 antigen like protein 2 DUF4304 PF14137.1 CCD22646.1 - 0.0085 16.2 0.1 0.063 13.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4304) FIST_C PF10442.4 CCD22646.1 - 0.018 14.9 0.0 0.026 14.4 0.0 1.3 1 0 0 1 1 1 0 FIST C domain Peptidase_C80 PF11713.3 CCD22646.1 - 0.035 13.9 0.1 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Peptidase C80 family DUF4015 PF13200.1 CCD22646.1 - 0.05 12.5 0.1 0.06 12.2 0.1 1.1 1 0 0 1 1 1 0 Putative glycosyl hydrolase domain DUF3818 PF12825.2 CCD22647.1 - 8.4e-127 422.5 16.4 8.4e-127 422.5 11.4 2.0 3 0 0 3 3 3 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CCD22647.1 - 6.3e-43 145.6 2.7 6.3e-43 145.6 1.8 2.7 2 0 0 2 2 2 1 PX-associated PX PF00787.19 CCD22647.1 - 1.2e-10 41.1 6.6 3.9e-10 39.5 1.7 3.4 2 1 0 2 2 2 1 PX domain Sec7 PF01369.15 CCD22648.1 - 2.8e-35 121.7 2.8 2.8e-35 121.7 2.0 2.1 2 0 0 2 2 2 1 Sec7 domain AviRa PF11599.3 CCD22648.1 - 0.17 10.8 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 RRNA methyltransferase AviRa PHF5 PF03660.9 CCD22649.1 - 3.9e-50 168.3 13.9 4.4e-50 168.2 9.6 1.0 1 0 0 1 1 1 1 PHF5-like protein DUF2404 PF10296.4 CCD22650.1 - 8.1e-31 106.0 0.1 1.7e-30 104.9 0.1 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 CCD22650.1 - 4.7e-11 42.8 0.2 2.2e-10 40.6 0.1 2.2 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 CCD22650.1 - 5.5e-05 23.3 0.0 0.0037 17.4 0.0 3.1 1 1 1 2 2 2 1 Pleckstrin homology domain gp32 PF08804.5 CCD22650.1 - 0.37 10.9 5.7 0.4 10.8 0.8 2.7 2 1 0 2 2 2 0 gp32 DNA binding protein like DIL PF01843.14 CCD22651.1 - 2.9e-11 43.1 6.7 8.9e-05 22.3 0.3 3.5 2 1 1 3 3 3 2 DIL domain Ank_5 PF13857.1 CCD22651.1 - 2e-06 27.8 0.2 6.7e-05 23.0 0.1 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCD22651.1 - 0.00026 21.2 0.1 0.00071 19.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCD22651.1 - 0.005 17.3 0.2 0.093 13.2 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Reo_sigmaC PF04582.7 CCD22652.1 - 0.00029 20.1 4.3 0.00029 20.1 3.0 2.2 1 1 1 2 2 2 1 Reovirus sigma C capsid protein BLOC1_2 PF10046.4 CCD22652.1 - 0.00099 19.2 9.2 0.00099 19.2 6.4 3.8 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.16 CCD22652.1 - 0.0012 18.3 22.3 0.002 17.6 15.4 1.3 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 CCD22652.1 - 0.0016 16.2 26.1 0.0021 15.8 17.4 1.4 1 1 0 1 1 1 1 Myosin tail IncA PF04156.9 CCD22652.1 - 0.01 15.4 31.1 0.16 11.5 20.5 2.6 1 1 1 2 2 2 0 IncA protein FliJ PF02050.11 CCD22652.1 - 0.039 14.0 27.0 0.48 10.4 3.3 3.4 1 1 2 3 3 3 0 Flagellar FliJ protein DUF3584 PF12128.3 CCD22652.1 - 0.084 10.1 24.1 0.11 9.7 16.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3450 PF11932.3 CCD22652.1 - 0.33 10.1 26.8 0.024 13.9 5.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Laminin_II PF06009.7 CCD22652.1 - 0.39 10.4 25.0 0.085 12.6 5.4 3.4 1 1 2 3 3 3 0 Laminin Domain II OmpH PF03938.9 CCD22652.1 - 0.56 10.1 24.7 1.4 8.8 8.1 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) HrpB7 PF09486.5 CCD22652.1 - 0.58 10.0 3.6 13 5.6 0.2 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) APG6 PF04111.7 CCD22652.1 - 0.72 8.8 31.5 0.031 13.3 13.5 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 YlqD PF11068.3 CCD22652.1 - 0.74 9.8 29.3 0.31 11.0 5.2 3.4 2 1 2 4 4 3 0 YlqD protein DUF4337 PF14235.1 CCD22652.1 - 1.6 8.5 13.1 0.068 13.0 2.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Tropomyosin_1 PF12718.2 CCD22652.1 - 1.9 8.3 28.0 0.14 11.9 9.8 2.5 1 1 1 2 2 2 0 Tropomyosin like Pro_CA PF00484.14 CCD22652.1 - 1.9 8.4 5.4 0.61 10.0 0.6 2.2 1 1 1 2 2 2 0 Carbonic anhydrase GLE1 PF07817.8 CCD22652.1 - 2 7.2 17.6 2.7 6.8 3.4 2.4 2 0 0 2 2 2 0 GLE1-like protein DUF342 PF03961.8 CCD22652.1 - 2.4 6.4 27.2 1 7.7 9.6 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Fmp27_WPPW PF10359.4 CCD22652.1 - 2.5 6.4 28.1 5.7 5.2 6.3 2.3 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF489 PF04356.7 CCD22652.1 - 2.9 7.4 17.5 0.18 11.3 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF489) Syntaxin PF00804.20 CCD22652.1 - 3.1 7.9 36.5 0.21 11.7 6.7 3.7 2 1 1 3 3 3 0 Syntaxin DivIVA PF05103.8 CCD22652.1 - 3.4 7.7 26.8 3.7 7.6 5.4 3.4 1 1 2 3 3 3 0 DivIVA protein CENP-F_leu_zip PF10473.4 CCD22652.1 - 3.7 7.3 27.1 3.9 7.3 10.2 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 CCD22652.1 - 6.1 6.8 24.3 0.7 9.8 7.8 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) NPV_P10 PF05531.7 CCD22652.1 - 7.3 6.9 23.3 3.3e+02 1.6 1.2 4.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Tup_N PF08581.5 CCD22652.1 - 9.7 6.4 28.8 0.16 12.1 7.7 4.4 2 1 2 4 4 3 0 Tup N-terminal WD40 PF00400.27 CCD22653.1 - 2.1e-07 30.5 1.5 1e-05 25.2 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat Ras PF00071.17 CCD22654.1 - 1.9e-05 24.0 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CCD22654.1 - 0.0062 17.0 0.0 0.056 13.9 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein AAA_28 PF13521.1 CCD22654.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Glyco_transf_20 PF00982.16 CCD22656.1 - 3.1e-204 678.8 0.0 3.5e-204 678.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 CCD22656.1 - 9.4e-05 21.8 0.3 0.01 15.2 0.1 2.9 2 1 0 2 2 2 2 Glycosyl transferases group 1 DIM1 PF02966.11 CCD22657.1 - 1.4e-67 225.3 0.6 1.5e-67 225.1 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CCD22657.1 - 4.5e-05 23.0 0.1 6.2e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin GTP_EFTU PF00009.22 CCD22658.1 - 7.7e-57 191.7 0.0 1.1e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCD22658.1 - 2.3e-35 120.6 0.0 7.1e-35 119.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCD22658.1 - 6.4e-17 61.4 2.2 6.4e-17 61.4 1.5 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCD22658.1 - 2.7e-05 23.7 0.6 2.7e-05 23.7 0.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCD22658.1 - 0.0019 18.1 0.2 0.0063 16.4 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RasGAP_C PF03836.10 CCD22659.1 - 0.0043 16.7 3.1 0.0097 15.6 2.1 1.5 1 0 0 1 1 1 1 RasGAP C-terminus DUF948 PF06103.6 CCD22659.1 - 0.042 13.7 0.0 0.085 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) WXG100 PF06013.7 CCD22659.1 - 0.046 13.7 1.0 6.7 6.7 0.1 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG RmuC PF02646.11 CCD22659.1 - 0.22 10.3 3.8 0.19 10.5 0.9 1.9 2 0 0 2 2 2 0 RmuC family Fzo_mitofusin PF04799.8 CCD22659.1 - 0.5 9.7 5.5 0.16 11.3 1.2 2.0 2 1 0 2 2 2 0 fzo-like conserved region EnY2 PF10163.4 CCD22659.1 - 0.97 9.4 8.1 0.1 12.5 2.1 1.9 2 0 0 2 2 2 0 Transcription factor e(y)2 Prefoldin PF02996.12 CCD22659.1 - 1 8.9 5.1 23 4.6 1.4 2.7 2 1 0 2 2 2 0 Prefoldin subunit Endotoxin_N PF03945.9 CCD22659.1 - 2.4 7.5 6.0 0.28 10.5 0.4 2.0 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain Syntaxin-6_N PF09177.6 CCD22659.1 - 2.8 8.4 6.0 17 5.9 0.1 2.8 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Opy2 PF09463.5 CCD22660.1 - 1.8e-10 40.7 18.3 2.7e-10 40.1 12.7 1.3 1 0 0 1 1 1 1 Opy2 protein Herpes_gE PF02480.11 CCD22660.1 - 0.0019 16.5 0.1 0.0033 15.7 0.0 1.4 1 1 0 1 1 1 1 Alphaherpesvirus glycoprotein E DGF-1_C PF11040.3 CCD22660.1 - 0.045 13.6 0.3 1.6 8.6 0.3 2.7 1 1 1 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus FAM176 PF14851.1 CCD22660.1 - 0.073 12.7 0.0 0.073 12.7 0.0 2.5 2 1 1 3 3 3 0 FAM176 family RXT2_N PF08595.6 CCD22660.1 - 8.5 6.1 15.0 0.42 10.3 2.6 2.3 2 0 0 2 2 2 0 RXT2-like, N-terminal Transketolase_N PF00456.16 CCD22661.1 - 9.7e-156 517.6 0.0 3.7e-155 515.7 0.0 1.8 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CCD22661.1 - 3e-47 160.3 0.0 4.9e-47 159.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCD22661.1 - 6.4e-12 45.5 0.0 1.8e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CCD22661.1 - 2.4e-05 23.4 0.0 0.0011 18.0 0.0 2.4 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 CCD22661.1 - 0.00034 19.4 0.0 0.0006 18.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component LMWPc PF01451.16 CCD22662.1 - 2.9e-38 131.3 0.0 3.2e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Not3 PF04065.10 CCD22663.1 - 1.9e-78 262.9 43.3 2.5e-77 259.3 22.7 3.3 2 1 0 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CCD22663.1 - 1.6e-23 83.0 22.6 2.4e-22 79.2 7.4 3.6 3 1 1 4 4 4 2 NOT2 / NOT3 / NOT5 family Plasmid_RAQPRD PF09686.5 CCD22663.1 - 0.67 10.0 3.5 3.5 7.7 0.1 3.3 4 0 0 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Cep57_MT_bd PF06657.8 CCD22663.1 - 4.5 7.2 12.0 1.2 9.1 2.7 2.6 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TPR_1 PF00515.23 CCD22665.1 - 6.3e-48 158.5 21.5 1.9e-07 30.4 0.0 10.9 10 1 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 CCD22665.1 - 1.2e-42 143.3 29.3 4e-11 42.4 0.6 7.1 3 2 3 7 7 7 6 TPR repeat TPR_2 PF07719.12 CCD22665.1 - 1.3e-40 134.0 27.9 9.8e-05 21.9 0.0 10.8 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_17 PF13431.1 CCD22665.1 - 2.1e-29 99.2 22.0 0.00015 21.6 0.1 11.6 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.1 CCD22665.1 - 2.4e-28 95.7 13.4 0.024 14.4 0.1 9.9 8 1 1 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 CCD22665.1 - 1.9e-27 95.0 36.3 4.2e-08 33.0 0.1 8.8 4 3 4 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 CCD22665.1 - 4.5e-19 68.6 49.1 8.5e-06 26.3 0.9 8.6 6 3 2 9 9 8 6 Tetratricopeptide repeat TPR_7 PF13176.1 CCD22665.1 - 1.1e-18 65.4 18.8 0.00042 19.8 0.2 9.8 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCD22665.1 - 2.2e-17 61.9 47.8 0.00023 21.5 0.3 11.5 5 2 8 13 13 10 7 Tetratricopeptide repeat TPR_19 PF14559.1 CCD22665.1 - 1.2e-16 60.7 44.4 6.9e-07 29.5 0.3 8.6 5 3 2 7 7 6 6 Tetratricopeptide repeat TPR_6 PF13174.1 CCD22665.1 - 8.5e-12 44.7 31.7 0.58 10.7 0.0 11.1 10 0 0 10 10 9 5 Tetratricopeptide repeat TPR_9 PF13371.1 CCD22665.1 - 1.5e-10 40.7 31.9 0.00015 21.5 0.0 7.0 4 1 3 7 7 6 5 Tetratricopeptide repeat TPR_15 PF13429.1 CCD22665.1 - 0.012 14.6 0.1 0.012 14.6 0.1 5.5 3 1 3 6 6 5 0 Tetratricopeptide repeat Med1 PF10744.4 CCD22666.1 - 2.5e-69 233.9 14.9 2.5e-69 233.9 10.4 1.6 2 0 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Novirhabdo_Nv PF05554.6 CCD22666.1 - 0.21 11.1 2.7 0.31 10.5 0.8 2.0 2 0 0 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein Hist_deacetyl PF00850.14 CCD22667.1 - 2.1e-70 237.4 0.0 3.4e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain EF-hand_1 PF00036.27 CCD22668.1 - 6.7e-18 62.5 3.8 3.6e-09 35.2 0.0 3.4 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.1 CCD22668.1 - 3e-17 62.4 1.6 3.1e-10 40.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CCD22668.1 - 2.7e-15 55.7 3.1 1.7e-08 33.9 0.1 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 CCD22668.1 - 3.7e-14 51.2 2.0 2.3e-08 33.2 0.1 3.3 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 CCD22668.1 - 9e-09 34.2 2.5 5.4e-08 31.8 0.0 2.7 3 1 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 CCD22668.1 - 0.00019 21.2 0.0 0.28 11.1 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CCD22668.1 - 0.0062 16.5 0.3 3.5 7.7 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region RNA_pol_Rpb4 PF03874.11 CCD22668.1 - 0.023 14.7 0.3 0.17 11.9 0.0 2.1 2 1 0 2 2 2 0 RNA polymerase Rpb4 DUF533 PF04391.7 CCD22668.1 - 0.024 13.9 0.1 0.026 13.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Fe-S_biosyn PF01521.15 CCD22670.1 - 2.8e-13 49.7 0.4 1.5e-06 28.1 0.1 2.2 1 1 1 2 2 2 2 Iron-sulphur cluster biosynthesis ThiF PF00899.16 CCD22671.1 - 1.2e-32 112.6 0.0 2.6e-32 111.5 0.0 1.6 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CCD22671.1 - 4.2e-16 58.2 0.8 1.5e-15 56.5 0.1 2.2 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCD22671.1 - 1.2e-08 34.1 0.9 2.5e-08 33.1 0.7 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CCD22671.1 - 0.00035 20.6 0.1 0.00091 19.3 0.1 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF3639 PF12341.3 CCD22671.1 - 0.0067 16.3 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) DUF4138 PF13595.1 CCD22671.1 - 0.038 12.9 0.0 0.085 11.8 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4138) Pho88 PF10032.4 CCD22672.1 - 4e-75 251.2 0.3 4.4e-75 251.1 0.2 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) HMG_box PF00505.14 CCD22673.1 - 7.3e-17 61.4 5.1 2.8e-16 59.5 3.5 2.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCD22673.1 - 2.2e-09 37.5 1.8 4.3e-09 36.6 1.2 1.5 1 0 0 1 1 1 1 HMG-box domain Vac_ImportDeg PF09783.4 CCD22674.1 - 1.7e-49 167.7 2.6 3.5e-49 166.6 1.8 1.5 1 0 0 1 1 1 1 Vacuolar import and degradation protein DUF2118 PF09891.4 CCD22674.1 - 0.29 10.8 0.0 0.29 10.8 0.0 2.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2118) Spc7_N PF15402.1 CCD22674.1 - 0.3 9.0 7.9 0.42 8.5 5.4 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 UPF0139 PF03669.8 CCD22675.1 - 0.0013 18.1 0.2 0.0059 16.1 0.1 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) dCMP_cyt_deam_1 PF00383.17 CCD22676.1 - 5.9e-23 80.4 0.0 7.5e-23 80.1 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CCD22676.1 - 0.0024 17.7 0.2 0.0047 16.7 0.1 1.5 1 1 1 2 2 2 1 Bd3614-like deaminase APOBEC_N PF08210.6 CCD22676.1 - 0.085 12.4 0.3 0.19 11.3 0.1 1.6 1 1 1 2 2 2 0 APOBEC-like N-terminal domain DnaJ PF00226.26 CCD22677.1 - 6.9e-16 57.7 2.5 3.1e-15 55.6 1.1 2.2 2 0 0 2 2 2 1 DnaJ domain CM_2 PF01817.16 CCD22678.1 - 1.6e-08 34.5 0.0 0.00093 19.2 0.0 3.3 2 1 1 3 3 3 2 Chorismate mutase type II Mito_carr PF00153.22 CCD22679.1 - 2.2e-57 190.7 2.0 2.6e-20 71.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SIP1 PF04938.7 CCD22680.1 - 0.0081 15.5 2.4 0.1 11.9 1.7 2.4 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Spectrin PF00435.16 CCD22680.1 - 0.05 13.8 0.9 0.089 13.0 0.6 1.5 1 0 0 1 1 1 0 Spectrin repeat Tfb4 PF03850.9 CCD22681.1 - 4.6e-106 354.1 0.2 5.4e-106 353.8 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 CCD22681.1 - 0.0032 17.5 0.0 0.0042 17.2 0.0 1.4 1 1 0 1 1 1 1 von Willebrand factor type A domain Sec8_exocyst PF04048.9 CCD22682.1 - 3.9e-44 149.7 10.3 1.7e-43 147.6 3.8 3.7 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain EST1 PF10374.4 CCD22682.1 - 7.4 6.5 10.1 1 9.3 0.2 4.0 4 1 0 4 4 4 0 Telomerase activating protein Est1 Pkinase PF00069.20 CCD22683.1 - 2.6e-57 193.9 0.8 5.7e-57 192.8 0.5 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22683.1 - 2.5e-27 95.5 0.1 7.8e-25 87.4 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCD22683.1 - 0.14 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD22683.1 - 0.14 11.8 0.1 0.24 11.0 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HMG_box PF00505.14 CCD22684.1 - 1e-25 89.7 0.7 1.4e-25 89.3 0.5 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCD22684.1 - 1.3e-18 67.0 0.7 2.1e-18 66.4 0.5 1.3 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 CCD22684.1 - 4e-05 23.2 0.0 5.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain HMG_box_5 PF14887.1 CCD22684.1 - 0.00024 20.8 0.3 0.00046 19.9 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 CCD22684.1 - 0.0064 16.6 0.1 0.014 15.5 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) YABBY PF04690.8 CCD22684.1 - 0.21 11.8 0.7 0.24 11.6 0.3 1.3 1 1 0 1 1 1 0 YABBY protein Acetyltransf_1 PF00583.19 CCD22685.1 - 3.5e-17 62.2 0.0 5e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 CCD22685.1 - 2e-08 34.2 0.0 2.3e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCD22685.1 - 2.1e-08 34.2 0.0 2.9e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCD22685.1 - 5.1e-06 26.1 0.1 8.1e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCD22685.1 - 7.2e-06 26.1 0.0 9e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCD22685.1 - 3e-05 24.1 0.0 3.6e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCD22685.1 - 7.6e-05 22.5 0.0 0.00025 20.8 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCD22685.1 - 0.0044 16.8 0.0 0.01 15.6 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Spc24 PF08286.6 CCD22685.1 - 0.17 11.5 0.7 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 ATG11 PF10377.4 CCD22686.1 - 1.2e-36 125.4 0.0 1.2e-36 125.4 0.0 2.8 2 0 0 2 2 2 1 Autophagy-related protein 11 tRNA-synt_2d PF01409.15 CCD22687.1 - 1.3e-43 148.9 0.1 3.4e-25 88.6 0.0 2.2 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CCD22687.1 - 4.4e-25 87.6 1.2 7.2e-25 87.0 0.1 1.9 3 0 0 3 3 3 1 Ferredoxin-fold anticodon binding domain Tweety PF04906.8 CCD22687.1 - 0.14 10.4 0.1 0.14 10.4 0.1 1.6 2 0 0 2 2 2 0 Tweety DUF3811 PF11656.3 CCD22687.1 - 6.2 6.9 6.3 1 9.4 0.1 2.5 2 1 0 2 2 2 0 YjbD family (DUF3811) Ribosomal_L16 PF00252.13 CCD22688.1 - 4.1e-34 117.1 0.0 7.5e-34 116.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rep_fac_C PF08542.6 CCD22689.1 - 1e-17 63.8 1.1 3.2e-17 62.2 0.1 2.2 2 1 1 3 3 3 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CCD22689.1 - 5.5e-11 42.3 2.0 9.6e-11 41.6 0.1 2.2 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 CCD22689.1 - 1.2e-05 25.5 0.3 5.3e-05 23.4 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta PF06144.8 CCD22689.1 - 0.0012 18.4 0.1 0.0091 15.5 0.0 2.3 2 1 0 2 2 2 1 DNA polymerase III, delta subunit NYD-SP12_N PF15015.1 CCD22689.1 - 0.031 12.5 0.0 0.045 12.0 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Sigma54_activ_2 PF14532.1 CCD22689.1 - 0.05 13.6 0.1 1.6 8.7 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain RuvB_N PF05496.7 CCD22689.1 - 0.071 12.1 0.1 2.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Adaptin_N PF01602.15 CCD22690.1 - 7.1e-109 364.4 23.4 8.8e-109 364.2 16.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 CCD22690.1 - 2.4e-07 30.7 0.0 6.5e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain ATP-synt_8 PF00895.15 CCD22690.1 - 0.037 14.2 0.5 0.037 14.2 0.3 3.8 3 0 0 3 3 3 0 ATP synthase protein 8 Anoctamin PF04547.7 CCD22691.1 - 5.5e-36 124.1 30.6 2.8e-35 121.8 15.9 3.8 4 1 0 4 4 4 2 Calcium-activated chloride channel Pol_alpha_B_N PF08418.5 CCD22692.1 - 5.4e-57 193.2 10.4 1e-56 192.2 7.2 1.5 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 CCD22692.1 - 1.7e-51 174.4 1.5 2.7e-51 173.7 1.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B ATP_synth_reg PF14960.1 CCD22692.1 - 0.032 13.4 0.1 0.089 11.9 0.0 1.7 1 0 0 1 1 1 0 ATP synthase regulation NOSIC PF08060.8 CCD22692.1 - 0.22 11.3 1.1 0.74 9.6 0.1 2.3 2 0 0 2 2 2 0 NOSIC (NUC001) domain CLASP_N PF12348.3 CCD22693.1 - 3e-50 170.7 21.0 1.5e-49 168.4 5.8 4.4 4 0 0 4 4 4 2 CLASP N terminal GTP_cyclohydro2 PF00925.15 CCD22694.1 - 7.9e-55 184.6 0.0 1.1e-49 167.8 0.0 2.2 2 0 0 2 2 2 2 GTP cyclohydrolase II KH_1 PF00013.24 CCD22695.1 - 1.4e-26 91.8 11.8 2.4e-09 36.7 0.3 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCD22695.1 - 2.7e-21 74.7 10.4 3.5e-09 36.0 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CCD22695.1 - 0.00016 21.1 14.5 0.005 16.3 0.4 3.6 3 1 0 3 3 3 3 KH domain KH_4 PF13083.1 CCD22695.1 - 0.00056 19.5 6.4 0.44 10.2 0.6 3.5 3 0 0 3 3 3 2 KH domain HTH_19 PF12844.2 CCD22695.1 - 0.1 12.6 1.0 0.51 10.4 0.0 2.5 2 1 0 2 2 2 0 Helix-turn-helix domain BSP_II PF05432.6 CCD22695.1 - 0.32 10.2 11.4 0.39 9.9 1.1 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) KH_5 PF13184.1 CCD22695.1 - 0.54 10.0 12.0 1.3 8.8 0.2 3.8 4 0 0 4 4 4 0 NusA-like KH domain RCR PF12273.3 CCD22695.1 - 4 8.0 8.0 2.9 8.4 3.0 2.2 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red B-block_TFIIIC PF04182.7 CCD22696.1 - 3.5 7.5 7.9 8 6.3 0.1 3.2 3 0 0 3 3 3 0 B-block binding subunit of TFIIIC Mito_carr PF00153.22 CCD22697.1 - 3.7e-71 234.9 5.8 6.2e-25 86.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PsbX PF06596.6 CCD22697.1 - 0.24 11.0 1.3 0.91 9.2 0.9 2.0 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) zf-ISL3 PF14690.1 CCD22698.1 - 0.054 13.5 0.6 9.5 6.3 0.0 2.3 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Lar_restr_allev PF14354.1 CCD22698.1 - 0.072 13.3 0.2 3.7 7.9 0.0 2.1 2 0 0 2 2 2 0 Restriction alleviation protein Lar Cys_rich_KTR PF14205.1 CCD22698.1 - 0.08 12.4 0.7 8.3 5.9 0.1 2.4 2 0 0 2 2 2 0 Cysteine-rich KTR RecR PF02132.10 CCD22698.1 - 0.1 12.0 2.4 0.58 9.6 0.1 2.2 2 0 0 2 2 2 0 RecR protein Cys_rich_CPCC PF14206.1 CCD22698.1 - 0.15 11.6 0.3 0.15 11.6 0.2 2.2 2 1 1 3 3 3 0 Cysteine-rich CPCC zf-ribbon_3 PF13248.1 CCD22698.1 - 0.18 11.0 2.2 0.75 9.0 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1 PF03811.8 CCD22698.1 - 0.23 10.9 2.2 5.8 6.4 0.1 2.2 2 0 0 2 2 2 0 InsA N-terminal domain DRP PF06044.7 CCD22698.1 - 0.3 10.0 2.1 1.5 7.7 0.3 2.0 2 0 0 2 2 2 0 Dam-replacing family Zn_Tnp_IS1595 PF12760.2 CCD22698.1 - 0.33 10.7 4.3 4.2 7.2 0.1 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 CCD22698.1 - 0.73 9.1 4.8 5.5 6.3 0.3 2.7 3 1 1 4 4 4 0 TFIIB zinc-binding zf-Mss51 PF13824.1 CCD22698.1 - 1 9.2 4.4 3.6 7.4 0.1 2.4 2 1 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2423 PF10338.4 CCD22701.1 - 6e-18 64.5 7.8 6e-18 64.5 5.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) Ribosomal_L19e PF01280.15 CCD22702.1 - 9.6e-59 197.4 10.0 9.6e-59 197.4 6.9 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e DUF349 PF03993.7 CCD22702.1 - 6.9 6.9 14.3 26 5.0 5.2 3.3 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) TEA PF01285.13 CCD22703.1 - 3.7e-34 118.6 0.8 3.7e-34 118.6 0.6 1.5 1 1 0 1 1 1 1 TEA/ATTS domain family UQ_con PF00179.21 CCD22704.1 - 3.6e-51 172.2 0.0 4e-51 172.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCD22704.1 - 4.4e-05 23.2 0.0 5.2e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCD22704.1 - 0.00025 20.9 0.0 0.00028 20.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CCD22704.1 - 0.0047 16.6 0.0 0.0078 15.8 0.0 1.3 1 0 0 1 1 1 1 UEV domain PRKCSH PF07915.8 CCD22706.1 - 1e-09 39.0 0.6 1e-09 39.0 0.4 3.9 4 1 0 4 4 4 1 Glucosidase II beta subunit-like protein Recep_L_domain PF01030.19 CCD22707.1 - 3e-11 43.2 9.0 0.0063 16.4 2.5 5.3 1 1 2 3 3 3 3 Receptor L domain LRR_9 PF14580.1 CCD22707.1 - 0.00067 19.2 0.3 0.0039 16.7 0.1 2.2 1 1 1 2 2 2 1 Leucine-rich repeat DUF4339 PF14237.1 CCD22707.1 - 0.033 13.7 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4339) ICAT PF06384.6 CCD22707.1 - 0.62 9.8 3.3 1.1 9.0 0.6 2.5 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT UQ_con PF00179.21 CCD22708.1 - 6.8e-45 151.9 0.0 1.1e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCD22708.1 - 0.012 15.3 0.0 0.043 13.5 0.0 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B Dfp1_Him1_M PF08630.5 CCD22709.1 - 1.4e-42 144.4 1.1 2.8e-42 143.4 0.0 2.1 2 0 0 2 2 2 1 Dfp1/Him1, central region zf-DBF PF07535.7 CCD22709.1 - 1.5e-20 72.5 1.6 3.5e-20 71.4 1.1 1.7 1 0 0 1 1 1 1 DBF zinc finger HHH_8 PF14716.1 CCD22709.1 - 0.0096 16.0 0.0 0.045 13.9 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain His_Phos_1 PF00300.17 CCD22710.1 - 2.7e-36 125.0 0.0 4.2e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) TIM PF00121.13 CCD22711.1 - 1.6e-90 302.4 0.1 1.8e-90 302.2 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase AP_endonuc_2 PF01261.19 CCD22711.1 - 0.1 11.8 0.1 0.2 10.8 0.0 1.4 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Alg14 PF08660.6 CCD22712.1 - 1.5e-45 155.2 0.2 1.9e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like HSP20 PF00011.16 CCD22714.1 - 8.3e-21 73.7 1.4 1.2e-20 73.2 1.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family YolD PF08863.5 CCD22714.1 - 0.079 12.8 0.2 0.079 12.8 0.1 1.7 2 0 0 2 2 2 0 YolD-like protein Ank_2 PF12796.2 CCD22715.1 - 4.5e-05 23.6 0.1 9.6e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCD22715.1 - 6.2e-05 23.0 0.1 0.00017 21.7 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CCD22715.1 - 0.001 18.7 0.1 0.0031 17.2 0.1 1.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.1 CCD22715.1 - 0.0099 16.0 0.6 0.041 14.1 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 CCD22715.1 - 0.032 14.7 0.2 0.085 13.3 0.0 1.8 2 0 0 2 2 2 0 Ankyrin repeats (many copies) zf-met PF12874.2 CCD22715.1 - 0.035 14.3 0.8 0.079 13.1 0.5 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type URO-D PF01208.12 CCD22716.1 - 7.5e-121 403.2 0.0 8.5e-121 403.0 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) AA_permease PF00324.16 CCD22717.1 - 3.8e-129 431.1 34.9 4.5e-129 430.8 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD22717.1 - 9.4e-35 119.9 35.6 1.2e-34 119.5 24.6 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM192 PF14802.1 CCD22717.1 - 0.0083 15.0 1.2 0.19 10.5 0.0 2.4 2 0 0 2 2 2 1 TMEM192 family DUF2207 PF09972.4 CCD22717.1 - 0.2 10.1 0.0 0.2 10.1 0.0 2.9 2 1 0 3 3 3 0 Predicted membrane protein (DUF2207) TFIIS_C PF01096.13 CCD22718.1 - 9.4e-22 76.3 8.7 1.1e-21 76.1 1.5 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CCD22718.1 - 4.5e-16 58.2 0.3 4.5e-16 58.2 0.2 2.0 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 CCD22718.1 - 0.0011 18.7 4.7 0.13 12.0 0.5 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain DUF2387 PF09526.5 CCD22718.1 - 0.058 13.3 3.3 0.75 9.7 0.1 2.3 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Elf1 PF05129.8 CCD22718.1 - 0.083 12.5 3.6 0.31 10.7 0.1 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like PhnA_Zn_Ribbon PF08274.7 CCD22718.1 - 0.089 12.5 0.4 0.089 12.5 0.3 3.0 3 0 0 3 3 3 0 PhnA Zinc-Ribbon zf-TFIIB PF13453.1 CCD22718.1 - 0.11 11.7 0.7 0.11 11.7 0.5 2.5 2 1 0 2 2 2 0 Transcription factor zinc-finger C1_4 PF07975.7 CCD22718.1 - 0.17 11.9 3.9 3.6 7.6 0.1 2.6 2 1 0 2 2 2 0 TFIIH C1-like domain DZR PF12773.2 CCD22718.1 - 0.57 10.0 5.6 1 9.2 0.1 2.7 2 1 0 2 2 2 0 Double zinc ribbon Baculo_LEF5_C PF11792.3 CCD22718.1 - 1.7 8.0 4.6 0.46 9.8 0.1 2.3 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain IBR PF01485.16 CCD22718.1 - 2.5 8.0 9.7 0.67 9.8 0.1 2.9 2 1 0 2 2 2 0 IBR domain zinc_ribbon_5 PF13719.1 CCD22718.1 - 5.6 6.6 13.8 17 5.1 1.1 4.0 3 1 1 4 4 4 0 zinc-ribbon domain Coprogen_oxidas PF01218.13 CCD22719.1 - 5.4e-127 422.4 0.0 6.1e-127 422.2 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase zf-H2C2_2 PF13465.1 CCD22720.1 - 0.00043 20.4 14.3 0.0023 18.1 2.0 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CCD22720.1 - 0.00057 20.0 17.4 0.00099 19.3 1.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD22720.1 - 0.00059 19.9 14.1 0.024 14.9 0.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CCD22720.1 - 0.072 13.3 0.3 0.072 13.3 0.2 2.9 2 1 1 3 3 3 0 Zinc-finger of C2H2 type FtsH_ext PF06480.10 CCD22721.1 - 0.13 12.4 0.7 11 6.2 0.0 2.2 2 0 0 2 2 2 0 FtsH Extracellular Ribosomal_S10 PF00338.17 CCD22722.1 - 1.6e-27 95.2 0.0 2.3e-27 94.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e E1-E2_ATPase PF00122.15 CCD22723.1 - 5.6e-65 218.6 6.0 1e-64 217.7 4.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCD22723.1 - 1.9e-33 115.5 0.6 1.9e-33 115.5 0.4 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCD22723.1 - 1.8e-26 93.9 0.0 7e-25 88.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCD22723.1 - 5.9e-17 61.4 0.0 1.2e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCD22723.1 - 2.5e-15 57.1 0.0 6.4e-15 55.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCD22723.1 - 2.8e-13 49.0 0.0 9.7e-13 47.3 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCD22723.1 - 0.00041 19.9 4.5 0.0013 18.4 0.6 2.7 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase tRNA-synt_2 PF00152.15 CCD22724.1 - 2.8e-88 295.9 0.7 2.8e-88 295.9 0.5 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCD22724.1 - 4.5e-12 45.6 0.4 9.2e-12 44.6 0.3 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCD22724.1 - 1.7e-07 30.7 0.0 0.0015 17.7 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Pkinase PF00069.20 CCD22725.1 - 4.7e-36 124.2 0.4 4.7e-36 124.2 0.3 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22725.1 - 9e-24 83.9 0.1 9e-24 83.9 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCD22725.1 - 0.035 13.8 1.7 0.79 9.4 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family ECH PF00378.15 CCD22726.1 - 1.5e-30 106.0 0.0 5.5e-30 104.2 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CCD22726.1 - 2.5e-17 63.0 0.1 7.2e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region RIH_assoc PF08454.6 CCD22726.1 - 0.58 9.7 4.3 4 7.1 0.1 3.0 2 1 1 3 3 3 0 RyR and IP3R Homology associated DUF2013 PF09431.5 CCD22727.1 - 0.0017 18.1 0.5 0.0038 16.9 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2013) Cnl2_NKP2 PF09447.5 CCD22727.1 - 0.016 14.8 0.3 0.11 12.2 0.0 2.5 2 0 0 2 2 2 0 Cnl2/NKP2 family protein DUF4351 PF14261.1 CCD22727.1 - 0.49 10.2 5.4 0.79 9.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4351) DASH_Dam1 PF08653.5 CCD22727.1 - 0.58 9.9 4.6 19 5.1 0.2 3.5 3 1 0 3 3 3 0 DASH complex subunit Dam1 Retrotrans_gag PF03732.12 CCD22727.1 - 0.73 9.9 6.5 0.18 11.8 0.4 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein DAHP_synth_1 PF00793.15 CCD22728.1 - 2.6e-100 334.5 0.0 3.2e-100 334.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family CYSTM PF12734.2 CCD22729.1 - 2e-08 34.1 17.1 2e-08 34.1 11.9 2.4 2 1 1 3 3 3 2 Cysteine-rich TM module stress tolerance Fungal_trans_2 PF11951.3 CCD22730.1 - 2e-24 85.9 0.2 2e-24 85.9 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD22730.1 - 2.2e-07 30.6 12.2 4.3e-07 29.7 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PRP1_N PF06424.7 CCD22731.1 - 3.3e-25 88.9 1.6 3.3e-25 88.9 1.1 2.8 2 1 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 CCD22731.1 - 4.4e-20 70.3 0.1 0.0078 16.7 0.0 9.9 7 4 5 12 12 11 5 Tetratricopeptide repeat TPR_11 PF13414.1 CCD22731.1 - 1.8e-14 53.1 5.8 0.0076 15.8 0.0 6.6 5 2 1 6 6 6 4 TPR repeat TPR_19 PF14559.1 CCD22731.1 - 4.9e-14 52.4 0.2 0.015 15.6 0.0 6.3 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCD22731.1 - 2.3e-11 44.0 0.0 0.094 13.4 0.0 6.2 4 1 4 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 CCD22731.1 - 9e-11 40.8 9.7 0.01 15.6 0.0 8.5 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCD22731.1 - 8.8e-10 38.3 1.7 0.14 12.1 0.0 5.5 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCD22731.1 - 3.9e-09 35.9 6.7 0.22 11.7 0.0 7.8 9 0 0 9 9 8 2 Tetratricopeptide repeat Apc3 PF12895.2 CCD22731.1 - 8e-06 25.9 4.7 0.00057 19.9 0.1 3.9 5 0 0 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCD22731.1 - 1.6e-05 25.0 7.2 0.13 12.8 0.1 6.1 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCD22731.1 - 2e-05 24.0 18.8 0.28 11.0 0.3 6.4 7 0 0 7 7 7 3 Tetratricopeptide repeat NARP1 PF12569.3 CCD22731.1 - 4.7e-05 22.3 0.8 0.087 11.5 0.1 3.1 1 1 2 3 3 3 2 NMDA receptor-regulated protein 1 TPR_7 PF13176.1 CCD22731.1 - 5.8e-05 22.5 0.4 19 5.3 0.0 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCD22731.1 - 0.0019 17.7 14.7 0.035 13.7 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat Bac_rhodopsin PF01036.13 CCD22732.1 - 3.3e-44 150.8 17.9 4.3e-44 150.4 12.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein FMN_red PF03358.10 CCD22733.1 - 7.4e-12 45.0 0.0 9.9e-12 44.6 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 CCD22733.1 - 4.6e-09 36.4 0.0 8.4e-09 35.5 0.0 1.5 2 0 0 2 2 2 1 Flavodoxin Flavodoxin_2 PF02525.12 CCD22733.1 - 0.00012 21.6 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 CCD22733.1 - 0.022 14.7 0.0 1.3 9.0 0.0 2.1 1 1 1 2 2 2 0 Flavodoxin domain WD40 PF00400.27 CCD22734.1 - 9.4e-19 66.5 2.6 0.00014 21.5 0.1 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Clathrin_propel PF01394.15 CCD22734.1 - 0.01 16.0 1.5 18 5.9 0.0 4.5 4 0 0 4 4 4 0 Clathrin propeller repeat DUF1752 PF08550.5 CCD22735.1 - 1.4e-09 37.3 2.6 2.8e-09 36.3 1.8 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) FoP_duplication PF13865.1 CCD22735.1 - 0.00085 19.7 2.5 0.0024 18.2 1.7 1.7 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 DUF2450 PF10475.4 CCD22736.1 - 8e-07 28.2 6.7 2.3e-06 26.7 4.6 1.8 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Vps54 PF07928.7 CCD22736.1 - 0.018 15.1 0.2 0.1 12.7 0.0 2.4 2 0 0 2 2 2 0 Vps54-like protein Myb_DNA-bind_6 PF13921.1 CCD22737.1 - 1.6e-18 66.5 10.8 4.7e-15 55.4 1.3 4.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCD22737.1 - 6.6e-18 64.4 12.0 1.3e-10 41.1 0.1 4.0 4 0 0 4 4 4 3 Myb-like DNA-binding domain Ribosomal_S17 PF00366.15 CCD22738.1 - 1.6e-29 101.7 5.3 2.7e-29 101.0 3.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 tRNA-synt_2b PF00587.20 CCD22739.1 - 3e-35 121.3 0.0 5.8e-35 120.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CCD22739.1 - 7.8e-20 70.9 9.7 7.8e-20 70.9 6.7 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain DUF342 PF03961.8 CCD22739.1 - 0.18 10.1 3.6 0.28 9.5 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Atg31 PF09795.4 CCD22740.1 - 1.8e-36 125.2 14.7 1.2e-35 122.6 10.2 1.8 1 1 0 1 1 1 1 Autophagy-related protein 31 DEAD PF00270.24 CCD22741.1 - 1.2e-40 138.7 2.9 1.9e-40 138.0 1.3 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD22741.1 - 1.5e-28 98.4 0.3 1.8e-27 95.0 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CCD22741.1 - 0.00046 19.8 0.0 0.0013 18.4 0.0 1.7 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CCD22741.1 - 0.002 18.2 1.6 0.0086 16.2 1.1 2.0 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 CCD22741.1 - 0.0049 15.9 1.3 0.0076 15.3 0.1 1.8 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.20 CCD22741.1 - 0.014 14.5 0.0 0.034 13.2 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Helicase_RecD PF05127.9 CCD22741.1 - 0.03 13.9 0.0 0.079 12.5 0.0 1.6 1 1 0 1 1 1 0 Helicase AAA_30 PF13604.1 CCD22741.1 - 0.06 12.9 0.1 0.15 11.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain PRK PF00485.13 CCD22742.1 - 4.2e-05 23.1 0.7 0.00088 18.8 0.5 2.6 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family GCV_T PF01571.16 CCD22743.1 - 1.4e-53 181.4 0.0 1.7e-53 181.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CCD22743.1 - 2.2e-14 53.2 0.0 4.1e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 CCD22743.1 - 0.0037 17.1 0.0 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 Sarcosine oxidase, gamma subunit family DUF4289 PF14121.1 CCD22743.1 - 0.07 11.5 0.1 0.1 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4289) Acyltransferase PF01553.16 CCD22744.1 - 3.4e-25 88.0 0.2 5.4e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase Cation_ATPase_N PF00690.21 CCD22744.1 - 0.53 9.7 4.4 8.4 5.9 0.2 2.6 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus IPK PF03770.11 CCD22745.1 - 1.3e-47 162.0 0.3 5.2e-47 160.0 0.2 2.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase DASH_Dad1 PF08649.5 CCD22746.1 - 2.2e-26 91.2 1.2 2.9e-26 90.9 0.8 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad1 UBN2 PF14223.1 CCD22746.1 - 0.082 12.6 0.1 0.097 12.4 0.1 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type CRCB PF02537.10 CCD22748.1 - 9e-32 109.4 19.9 7.6e-20 70.9 4.6 2.6 2 1 0 2 2 2 2 CrcB-like protein DUF4131 PF13567.1 CCD22748.1 - 4.3 6.7 11.5 0.21 10.9 2.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Nab2 PF11517.3 CCD22749.1 - 0.015 15.3 0.2 0.035 14.1 0.1 1.6 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Sld5 PF05916.6 CCD22750.1 - 2.1e-11 44.0 1.8 3.3e-11 43.4 1.2 1.3 1 0 0 1 1 1 1 GINS complex protein Cas_DxTHG PF09455.5 CCD22750.1 - 0.2 10.7 4.3 0.32 10.0 3.0 1.3 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family Cullin_Nedd8 PF10557.4 CCD22750.1 - 0.21 11.4 3.0 9.2 6.1 0.7 2.7 2 0 0 2 2 2 0 Cullin protein neddylation domain CortBP2 PF09727.4 CCD22750.1 - 0.24 10.9 8.9 0.12 11.8 4.0 1.9 2 0 0 2 2 2 0 Cortactin-binding protein-2 Methyltransf_31 PF13847.1 CCD22751.1 - 7.7e-13 48.3 0.1 2.3e-12 46.7 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCD22751.1 - 3.7e-12 45.9 0.2 8.1e-12 44.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CCD22751.1 - 3.6e-10 40.4 0.1 2.3e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCD22751.1 - 3.3e-08 33.9 0.0 9.6e-08 32.4 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCD22751.1 - 6e-08 32.7 0.0 1.2e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCD22751.1 - 1.1e-07 31.7 0.0 4.9e-07 29.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CCD22751.1 - 2.6e-07 29.9 0.0 3.6e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CCD22751.1 - 1.4e-06 28.5 0.1 5.8e-06 26.6 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCD22751.1 - 1.7e-06 26.9 0.0 2.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.9 CCD22751.1 - 2.2e-06 27.1 0.1 4.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain PRMT5 PF05185.11 CCD22751.1 - 1.6e-05 24.0 0.0 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.7 CCD22751.1 - 4.5e-05 23.8 0.3 0.00014 22.2 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain FtsJ PF01728.14 CCD22751.1 - 0.00012 22.1 0.0 0.00082 19.4 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.14 CCD22751.1 - 0.0012 18.4 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 CCD22751.1 - 0.0013 18.1 0.1 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Met_10 PF02475.11 CCD22751.1 - 0.0032 17.0 0.1 0.0055 16.3 0.1 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.13 CCD22751.1 - 0.006 15.7 0.1 0.0099 15.0 0.1 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CCD22751.1 - 0.029 13.4 0.1 0.06 12.3 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 CCD22751.1 - 0.041 13.4 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 CCD22751.1 - 0.049 13.3 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L4 PF00573.17 CCD22752.1 - 7.9e-47 159.1 1.9 1.8e-46 158.0 1.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CCD22752.1 - 6.8e-29 99.5 3.6 3.1e-28 97.4 0.7 2.6 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain SET PF00856.23 CCD22753.1 - 1.7e-11 44.6 0.8 3.8e-05 24.0 0.0 3.9 3 1 0 3 3 3 2 SET domain Aha1_N PF09229.6 CCD22754.1 - 1.1e-29 103.0 1.1 1.3e-29 102.7 0.8 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal RNase_P_pop3 PF08228.6 CCD22755.1 - 3.6e-42 143.8 0.1 5.5e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 WSC PF01822.14 CCD22756.1 - 2.6e-11 43.2 11.0 2.6e-11 43.2 7.6 2.4 2 0 0 2 2 2 1 WSC domain Adeno_E3_CR2 PF02439.10 CCD22756.1 - 1.9e-05 24.0 3.2 4.1e-05 23.0 2.2 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 SKG6 PF08693.5 CCD22756.1 - 0.00016 20.8 4.2 0.00069 18.8 2.9 2.1 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 CCD22756.1 - 0.0036 17.6 0.1 0.018 15.4 0.0 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 CCD22756.1 - 0.0043 16.7 7.0 0.0043 16.7 4.8 2.3 1 1 1 2 2 2 1 Rifin/stevor family Syndecan PF01034.15 CCD22756.1 - 0.0087 15.6 0.1 0.02 14.5 0.1 1.5 1 0 0 1 1 1 1 Syndecan domain TrbL PF04610.9 CCD22756.1 - 0.042 13.5 1.6 0.13 11.9 1.1 1.8 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Ribosomal_L18e PF00828.14 CCD22757.1 - 9.6e-24 84.2 2.4 1.2e-23 83.9 0.5 1.8 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Adaptin_N PF01602.15 CCD22758.1 - 3.6e-110 368.7 11.7 4.7e-110 368.3 8.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CCD22758.1 - 9.1e-46 155.4 1.8 2.4e-45 154.0 1.2 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CCD22758.1 - 1.5e-09 37.9 0.6 0.00065 19.9 0.2 5.7 2 2 3 5 5 5 2 HEAT repeats HEAT PF02985.17 CCD22758.1 - 0.0051 16.7 0.7 4.1 7.7 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.2 CCD22758.1 - 0.0087 15.9 12.7 0.36 10.6 1.2 4.2 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.1 CCD22758.1 - 0.051 14.0 0.3 0.53 10.8 0.4 2.7 2 1 0 2 2 2 0 HEAT-like repeat Rcd1 PF04078.8 CCD22759.1 - 1.6e-119 397.5 2.6 1.9e-119 397.3 1.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Cyclin_N PF00134.18 CCD22760.1 - 1.8e-21 76.0 0.0 6.8e-21 74.1 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCD22760.1 - 3.9e-11 43.5 0.0 8.5e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin DNA_pol3_delta2 PF13177.1 CCD22761.1 - 8.7e-18 64.4 0.0 1.1e-15 57.6 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CCD22761.1 - 1.4e-17 64.1 0.0 2.3e-17 63.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 CCD22761.1 - 3.9e-15 55.5 0.1 9.2e-15 54.4 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 CCD22761.1 - 5.3e-08 31.9 0.0 4.5e-06 25.6 0.0 2.3 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CCD22761.1 - 9.6e-08 32.2 1.5 0.01 15.9 0.1 3.2 2 2 1 3 3 3 2 AAA domain RuvB_N PF05496.7 CCD22761.1 - 1.2e-06 27.7 0.0 2.9e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCD22761.1 - 2.8e-06 27.4 0.1 4e-05 23.6 0.1 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CCD22761.1 - 4.7e-06 26.5 0.0 9.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 CCD22761.1 - 6.4e-06 25.7 0.2 1.1e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 CCD22761.1 - 4.8e-05 23.0 0.1 0.00015 21.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CCD22761.1 - 8.9e-05 21.5 0.0 0.00013 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 CCD22761.1 - 0.00012 21.5 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 CCD22761.1 - 0.00012 20.8 0.0 0.054 12.1 0.0 2.1 2 0 0 2 2 2 2 TIP49 C-terminus AAA_19 PF13245.1 CCD22761.1 - 0.00013 21.6 0.0 0.00032 20.3 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CCD22761.1 - 0.00024 21.9 0.1 0.0026 18.5 0.0 2.2 1 1 1 2 2 2 1 AAA domain ResIII PF04851.10 CCD22761.1 - 0.00041 20.2 0.1 0.013 15.3 0.0 2.4 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 CCD22761.1 - 0.00076 19.2 0.1 0.0037 16.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CCD22761.1 - 0.0011 18.3 0.3 0.026 13.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 CCD22761.1 - 0.0014 18.1 0.1 0.015 14.7 0.1 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_18 PF13238.1 CCD22761.1 - 0.0017 18.6 0.0 0.0054 17.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_10 PF12846.2 CCD22761.1 - 0.0019 17.6 0.4 0.24 10.7 0.3 2.8 1 1 0 1 1 1 1 AAA-like domain Viral_helicase1 PF01443.13 CCD22761.1 - 0.0022 17.5 0.0 0.0066 15.9 0.0 1.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 CCD22761.1 - 0.0024 17.5 0.0 0.0049 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CCD22761.1 - 0.005 16.4 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CCD22761.1 - 0.0086 15.9 0.0 0.02 14.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCD22761.1 - 0.0096 15.5 0.2 0.25 10.8 0.0 2.4 2 1 0 2 2 1 1 AAA domain Arch_ATPase PF01637.13 CCD22761.1 - 0.011 15.5 0.1 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase Mg_chelatase PF01078.16 CCD22761.1 - 0.015 14.4 0.0 0.085 12.0 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CCD22761.1 - 0.025 14.7 0.0 0.049 13.8 0.0 1.6 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 CCD22761.1 - 0.031 14.2 0.0 0.059 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 CCD22761.1 - 0.037 13.2 0.1 4.1 6.5 0.0 2.3 1 1 0 2 2 2 0 PhoH-like protein MobB PF03205.9 CCD22761.1 - 0.044 13.4 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CCD22761.1 - 0.048 13.9 0.1 0.22 11.8 0.0 2.1 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 CCD22761.1 - 0.056 12.4 0.1 0.22 10.4 0.1 1.8 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Prenyltransf PF01255.14 CCD22761.1 - 0.11 11.5 0.1 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase Mid1 PF12929.2 CCD22762.1 - 1.1e-133 446.1 15.2 1.4e-133 445.7 10.6 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 CCD22762.1 - 0.054 13.8 1.2 3.3 8.0 0.1 2.5 2 0 0 2 2 2 0 Fz domain TruB_N PF01509.13 CCD22763.1 - 7.3e-41 139.7 1.1 2.4e-39 134.8 0.0 2.9 3 0 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) RabGAP-TBC PF00566.13 CCD22764.1 - 2.8e-44 151.1 4.5 9.5e-32 110.2 0.1 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PalH PF08733.5 CCD22765.1 - 3e-82 276.2 14.9 3.8e-82 275.9 10.3 1.1 1 0 0 1 1 1 1 PalH/RIM21 DUF4149 PF13664.1 CCD22765.1 - 4.8 7.3 10.3 16 5.6 0.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Pet20 PF08692.5 CCD22766.1 - 8.2e-08 32.2 0.1 5.4e-07 29.6 0.0 2.4 1 1 0 1 1 1 1 Mitochondrial protein Pet20 DUF869 PF05911.6 CCD22766.1 - 0.013 13.7 2.5 0.017 13.4 1.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Sec7_N PF12783.2 CCD22767.1 - 1.8e-35 121.8 7.4 1.8e-35 121.8 5.1 4.0 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Pkinase PF00069.20 CCD22768.1 - 1.1e-66 224.6 0.0 1.8e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22768.1 - 1e-50 172.2 0.0 1.8e-50 171.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CCD22768.1 - 3e-22 78.7 0.3 1.7e-21 76.4 0.2 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 CCD22768.1 - 1e-11 44.9 1.6 2.7e-11 43.5 1.1 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CCD22768.1 - 2.1e-07 30.2 0.0 3.9e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 CCD22768.1 - 2.8e-05 24.3 1.8 8.5e-05 22.7 1.2 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 CCD22768.1 - 0.017 14.8 0.2 0.044 13.4 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family NTP_transf_2 PF01909.18 CCD22769.1 - 5.9e-16 58.5 0.0 5.9e-16 58.5 0.0 2.6 2 1 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CCD22769.1 - 2.3e-13 49.8 0.0 2.3e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase Ribosomal_L18e PF00828.14 CCD22770.1 - 6.1e-26 91.3 0.1 9.4e-26 90.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Ribosomal_S19e PF01090.14 CCD22771.1 - 1.6e-54 183.1 0.1 1.7e-54 183.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RRM_1 PF00076.17 CCD22772.1 - 6e-36 121.9 0.3 4.2e-19 67.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD22772.1 - 8.2e-32 109.0 0.0 1.1e-15 57.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD22772.1 - 1.3e-11 44.1 0.0 8.9e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.4 CCD22772.1 - 0.0035 15.7 7.1 0.0039 15.5 4.9 1.2 1 0 0 1 1 1 1 Transmembrane protein OB_RNB PF08206.6 CCD22772.1 - 0.054 13.0 0.1 14 5.2 0.0 2.6 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF605 PF04652.11 CCD22772.1 - 1.1 8.6 48.9 1.3 8.3 2.2 2.1 2 0 0 2 2 2 0 Vta1 like Vfa1 PF08432.5 CCD22772.1 - 1.4 8.9 23.3 2.9 7.8 16.1 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 LMBR1 PF04791.11 CCD22772.1 - 6.1 5.3 5.0 8.4 4.8 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ras PF00071.17 CCD22773.1 - 4.7e-28 97.6 0.1 2.4e-23 82.3 0.0 2.5 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CCD22773.1 - 8e-13 48.9 0.3 1.9e-06 28.3 0.0 2.7 1 1 0 2 2 2 2 Miro-like protein Bax1-I PF01027.15 CCD22774.1 - 2.9e-38 131.5 22.4 4.2e-38 131.0 15.5 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Orbi_NS3 PF01616.11 CCD22774.1 - 0.19 10.6 6.2 1.6 7.6 0.1 2.5 2 1 0 2 2 2 0 Orbivirus NS3 PAP2 PF01569.16 CCD22774.1 - 3 7.5 15.2 7 6.3 9.6 2.3 1 1 1 2 2 2 0 PAP2 superfamily Ribosomal_L23 PF00276.15 CCD22775.1 - 7.9e-18 64.1 1.3 9.5e-18 63.9 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 Lipoprotein_1 PF00820.14 CCD22775.1 - 0.017 14.1 0.2 0.02 13.9 0.2 1.0 1 0 0 1 1 1 0 Borrelia lipoprotein Levi_coat PF01819.12 CCD22775.1 - 0.033 13.7 0.1 0.039 13.5 0.1 1.1 1 0 0 1 1 1 0 Levivirus coat protein Ribosomal_S11 PF00411.14 CCD22776.1 - 9.4e-07 28.9 0.1 2.1e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 UPF0220 PF05255.6 CCD22777.1 - 2.7e-45 153.5 3.5 3.3e-45 153.3 2.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Voltage_CLC PF00654.15 CCD22777.1 - 0.029 13.3 4.3 0.036 13.0 3.0 1.2 1 0 0 1 1 1 0 Voltage gated chloride channel CitMHS PF03600.11 CCD22777.1 - 0.049 12.2 5.6 0.06 11.9 3.9 1.0 1 0 0 1 1 1 0 Citrate transporter Kri1_C PF12936.2 CCD22778.1 - 1.3e-29 101.9 4.6 1.3e-29 101.9 3.2 5.4 6 1 1 7 7 7 1 KRI1-like family C-terminal Kri1 PF05178.7 CCD22778.1 - 5.5e-15 55.4 25.8 5.5e-15 55.4 17.9 7.0 5 3 1 6 6 6 1 KRI1-like family CorA PF01544.13 CCD22779.1 - 1.7e-39 135.6 9.5 1.5e-25 89.8 1.2 2.3 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein zf-DNL PF05180.7 CCD22781.1 - 2.6e-31 107.1 1.6 4.3e-31 106.4 1.1 1.4 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 CCD22781.1 - 0.024 14.2 0.4 0.044 13.4 0.3 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 CCD22781.1 - 0.084 12.5 1.1 2.8 7.7 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-CSL PF05207.8 CCD22781.1 - 0.086 12.3 0.2 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 CSL zinc finger zinc_ribbon_5 PF13719.1 CCD22781.1 - 0.12 12.0 1.1 3.8 7.1 0.0 2.4 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 CCD22781.1 - 2.7 7.6 5.6 31 4.3 4.0 2.3 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) SGL PF08450.7 CCD22782.1 - 4.2e-55 186.7 0.0 7.1e-55 186.0 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 CCD22782.1 - 5.5e-05 23.0 0.0 2.5 8.1 0.0 3.4 3 0 0 3 3 3 3 Arylesterase DUF1752 PF08550.5 CCD22783.1 - 0.062 12.8 1.2 0.19 11.3 0.8 1.8 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) Myb_DNA-bind_6 PF13921.1 CCD22784.1 - 1.1e-17 63.8 19.8 5.8e-15 55.1 4.1 3.8 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCD22784.1 - 2.6e-17 62.6 11.0 5.8e-10 39.0 1.0 4.0 4 0 0 4 4 4 3 Myb-like DNA-binding domain PsbW PF07123.7 CCD22784.1 - 0.77 9.8 6.0 0.18 11.8 1.2 2.1 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) MADF_DNA_bdg PF10545.4 CCD22784.1 - 1.2 9.3 15.9 0.33 11.1 2.2 4.3 3 1 0 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_4 PF13837.1 CCD22784.1 - 3.2 7.9 24.6 0.82 9.8 0.1 5.6 4 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain DXP_reductoisom PF02670.11 CCD22784.1 - 3.5 8.1 8.4 1.9 9.0 0.5 3.0 3 0 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF2408 PF10303.4 CCD22785.1 - 0.45 10.6 4.1 15 5.7 0.7 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) ADH_zinc_N PF00107.21 CCD22786.1 - 8.1e-29 99.8 0.0 1.2e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCD22786.1 - 7.3e-11 43.0 0.0 1.8e-10 41.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCD22786.1 - 8.4e-11 41.6 0.0 1.8e-10 40.5 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Cpn60_TCP1 PF00118.19 CCD22788.1 - 2.9e-15 55.8 1.5 4.8e-15 55.1 1.1 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ARL2_Bind_BART PF11527.3 CCD22789.1 - 0.05 13.3 0.2 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Sulfate_tra_GLY PF13792.1 CCD22789.1 - 0.087 12.5 2.9 0.2 11.3 2.0 1.6 1 0 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif Acyltransferase PF01553.16 CCD22790.1 - 3.2e-30 104.2 0.0 1.2e-29 102.4 0.0 1.9 1 1 1 2 2 2 1 Acyltransferase AMP-binding PF00501.23 CCD22791.1 - 1.5e-62 211.3 0.0 1.8e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCD22791.1 - 0.00017 22.4 0.1 0.00031 21.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Fig1 PF12351.3 CCD22792.1 - 2.3e-54 184.0 6.9 2.3e-54 184.0 4.8 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 CCD22792.1 - 0.00037 20.1 21.4 0.0014 18.2 14.9 1.8 1 1 0 1 1 1 1 SUR7/PalI family DUF3278 PF11683.3 CCD22792.1 - 1.8 8.5 9.2 0.76 9.7 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) ATP-synt PF00231.14 CCD22793.1 - 5.4e-65 219.5 5.3 6.2e-65 219.4 3.7 1.0 1 0 0 1 1 1 1 ATP synthase CsrA PF02599.11 CCD22793.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 Global regulator protein family Methyltransf_31 PF13847.1 CCD22794.1 - 1.9e-13 50.3 0.0 4.1e-13 49.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCD22794.1 - 2.4e-12 46.6 0.0 3.5e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CCD22794.1 - 3.3e-11 43.7 0.0 4.4e-10 40.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCD22794.1 - 8.9e-11 41.8 0.0 2.2e-10 40.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCD22794.1 - 1.4e-08 35.0 0.0 6.1e-08 33.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCD22794.1 - 5e-07 29.2 0.0 8.7e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 CCD22794.1 - 1.1e-06 27.6 0.1 1.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 CCD22794.1 - 1.6e-06 27.9 0.0 3.5e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD22794.1 - 2.6e-06 27.7 0.0 1e-05 25.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.11 CCD22794.1 - 4.3e-06 25.9 0.0 5.2e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase CMAS PF02353.15 CCD22794.1 - 3.2e-05 23.1 0.0 4.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CCD22794.1 - 0.00011 22.5 0.0 0.00024 21.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 CCD22794.1 - 0.00032 20.1 0.0 0.0005 19.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 CCD22794.1 - 0.00073 19.5 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.11 CCD22794.1 - 0.0024 17.5 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 CCD22794.1 - 0.012 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 CCD22794.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 CCD22794.1 - 0.021 14.5 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 CCD22794.1 - 0.046 12.9 0.0 0.067 12.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.12 CCD22794.1 - 0.057 12.4 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 CCD22794.1 - 0.078 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.10 CCD22794.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PNPOx_C PF10590.4 CCD22795.1 - 5.9e-21 73.6 3.4 1.5e-20 72.3 2.3 1.8 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 CCD22795.1 - 8.7e-10 38.4 0.0 1.4e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Carn_acyltransf PF00755.15 CCD22796.1 - 3.1e-186 619.9 0.7 3.9e-186 619.6 0.5 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Oxysterol_BP PF01237.13 CCD22797.1 - 1.8e-128 427.9 0.0 3.3e-128 427.1 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_2 PF12796.2 CCD22797.1 - 1.8e-17 63.4 0.0 2.2e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCD22797.1 - 4.4e-16 58.5 0.3 9.5e-07 28.8 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCD22797.1 - 6.8e-13 48.7 0.6 0.00014 22.2 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD22797.1 - 3.5e-12 45.2 0.1 0.00018 21.4 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.25 CCD22797.1 - 6.6e-12 44.6 0.4 0.00025 20.7 0.0 3.3 4 0 0 4 4 4 2 Ankyrin repeat PH PF00169.24 CCD22797.1 - 8.8e-11 41.9 1.6 3.1e-10 40.1 0.3 2.4 2 0 0 2 2 2 1 PH domain PH_8 PF15409.1 CCD22797.1 - 6.8e-09 35.6 0.2 2.4e-08 33.9 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 CCD22797.1 - 6.3e-08 32.8 0.7 6.3e-08 32.8 0.5 2.8 3 0 0 3 3 3 1 Pleckstrin homology domain zf-C2H2_4 PF13894.1 CCD22798.1 - 1.3e-05 25.2 2.8 0.12 12.7 0.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCD22798.1 - 0.00023 21.3 8.5 0.053 13.8 0.2 3.2 2 1 0 2 2 2 2 Zinc finger, C2H2 type SAICAR_synt PF01259.13 CCD22799.1 - 1e-93 313.0 0.5 1.2e-93 312.8 0.3 1.0 1 0 0 1 1 1 1 SAICAR synthetase EMP24_GP25L PF01105.19 CCD22800.1 - 2e-30 105.8 0.4 2.6e-30 105.4 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pkinase PF00069.20 CCD22801.1 - 1.9e-40 138.6 0.0 3.8e-23 81.9 0.0 3.3 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22801.1 - 1.2e-14 54.0 0.0 3e-10 39.6 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 CCD22801.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CCD22801.1 - 0.03 13.2 0.0 7.7 5.3 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Steroid_dh PF02544.11 CCD22802.1 - 8.6e-35 119.7 10.4 1.4e-34 119.0 7.2 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Fibrillarin PF01269.12 CCD22803.1 - 2e-110 367.1 0.0 2.4e-110 366.8 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CCD22803.1 - 1.3e-05 24.8 0.1 2.3e-05 23.9 0.1 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CCD22803.1 - 0.076 12.5 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Mannosyl_trans3 PF11051.3 CCD22804.1 - 2e-85 286.4 0.0 3.2e-85 285.7 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative zf-RING_5 PF14634.1 CCD22805.1 - 0.0011 18.6 0.1 0.0026 17.4 0.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCD22805.1 - 0.0043 17.0 0.1 0.0099 15.8 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCD22805.1 - 0.005 16.4 0.1 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCD22805.1 - 0.013 15.3 0.2 0.028 14.2 0.1 1.5 1 0 0 1 1 1 0 Ring finger domain IBR PF01485.16 CCD22805.1 - 0.036 13.9 2.0 3.1 7.7 0.4 2.5 1 1 1 2 2 2 0 IBR domain zf-C3HC4_4 PF15227.1 CCD22805.1 - 0.039 13.8 0.1 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Fer2_3 PF13085.1 CCD22805.1 - 0.075 12.8 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-Apc11 PF12861.2 CCD22806.1 - 1.4e-41 140.2 2.7 2.1e-41 139.6 1.9 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CCD22806.1 - 2.9e-28 97.7 5.0 5.5e-28 96.8 3.5 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCD22806.1 - 2.5e-07 30.4 15.9 9.8e-07 28.5 11.0 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCD22806.1 - 0.00064 19.6 12.9 0.0034 17.3 8.9 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCD22806.1 - 0.005 16.4 12.4 0.16 11.6 8.6 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCD22806.1 - 0.0087 15.7 13.5 0.033 13.9 9.5 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCD22806.1 - 0.01 15.7 3.3 0.01 15.7 2.3 2.1 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CCD22806.1 - 0.013 15.0 15.2 0.075 12.7 10.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CCD22806.1 - 0.015 15.2 16.9 0.25 11.3 11.7 3.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 CCD22806.1 - 0.02 14.4 2.2 0.02 14.4 1.5 2.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 CCD22806.1 - 0.35 10.6 4.9 1.1 9.0 3.2 1.9 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 CCD22806.1 - 0.74 9.8 6.8 0.32 10.9 2.9 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CCD22806.1 - 0.83 9.8 8.1 2.4 8.3 5.5 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HIT PF04438.11 CCD22806.1 - 1.1 8.9 8.8 0.36 10.5 2.9 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-RING-like PF08746.6 CCD22806.1 - 4.9 7.2 10.3 23 5.0 7.2 2.1 1 1 0 1 1 1 0 RING-like domain Tcp11 PF05794.8 CCD22807.1 - 2.4e-120 402.2 4.5 5.9e-120 400.9 3.1 1.7 1 0 0 1 1 1 1 T-complex protein 11 Maf1 PF09174.5 CCD22808.1 - 5.3e-49 166.4 16.7 3e-48 164.0 1.1 3.1 1 1 0 2 2 2 2 Maf1 regulator Rad51 PF08423.6 CCD22809.1 - 4e-31 107.8 0.1 1.8e-30 105.6 0.0 1.9 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CCD22809.1 - 3.3e-09 36.4 0.0 6.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 CCD22809.1 - 5.2e-05 22.4 0.4 9.5e-05 21.6 0.3 1.5 1 1 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CCD22809.1 - 0.0001 21.5 3.6 0.00088 18.4 2.5 2.4 1 1 0 1 1 1 1 KaiC AAA_22 PF13401.1 CCD22809.1 - 0.0063 16.6 0.2 0.016 15.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCD22809.1 - 0.34 10.8 4.0 1.1 9.1 0.7 2.8 2 1 0 2 2 2 0 AAA domain RCR PF12273.3 CCD22810.1 - 1.1e-41 142.4 4.5 2.3e-41 141.4 2.9 1.7 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red ATG27 PF09451.5 CCD22810.1 - 0.037 13.2 0.1 0.056 12.6 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 DUF4381 PF14316.1 CCD22810.1 - 0.039 14.0 0.6 0.066 13.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) GP41 PF00517.12 CCD22810.1 - 0.042 13.4 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein WBP-1 PF11669.3 CCD22810.1 - 0.052 13.6 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF3753 PF12575.3 CCD22810.1 - 0.071 12.9 1.7 0.074 12.8 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Rhabdo_glycop PF00974.13 CCD22810.1 - 0.19 9.9 0.1 0.25 9.5 0.1 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein polyprenyl_synt PF00348.12 CCD22811.1 - 1.7e-50 171.3 0.0 1.7e-22 79.5 0.0 3.1 3 0 0 3 3 3 3 Polyprenyl synthetase Cofilin_ADF PF00241.15 CCD22812.1 - 1.2e-24 86.6 0.9 1.3e-12 47.6 0.2 2.4 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein PI3_PI4_kinase PF00454.22 CCD22813.1 - 3.1e-50 170.8 0.1 8.8e-50 169.3 0.1 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 CCD22813.1 - 7.7e-31 106.2 2.7 4e-30 103.9 0.2 3.2 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 CCD22813.1 - 8.7e-14 50.6 0.6 3.2e-13 48.8 0.0 2.3 2 0 0 2 2 2 1 FATC domain CKS PF01111.14 CCD22814.1 - 3e-35 119.8 0.1 4.6e-35 119.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PRMT5 PF05185.11 CCD22815.1 - 4.5e-150 500.4 7.1 6.1e-150 500.0 4.9 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Pkinase PF00069.20 CCD22816.1 - 6.8e-52 176.1 0.0 1.2e-51 175.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22816.1 - 1.1e-22 80.4 0.0 2e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD22816.1 - 0.0016 17.4 0.1 0.0063 15.5 0.0 1.9 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 CCD22816.1 - 0.0033 17.1 0.0 1.3 8.7 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CCD22816.1 - 0.033 13.5 0.0 3.7 6.8 0.0 2.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase PF00069.20 CCD22817.1 - 6.8e-57 192.5 0.3 3e-56 190.4 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22817.1 - 1.1e-23 83.6 0.0 1.8e-23 82.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD22817.1 - 0.019 13.9 0.4 0.067 12.1 0.0 2.1 2 1 0 2 2 2 0 Kinase-like APH PF01636.18 CCD22817.1 - 0.24 11.1 0.1 0.43 10.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family NAD_Gly3P_dh_N PF01210.18 CCD22818.1 - 3.5e-53 179.5 0.1 5.4e-53 178.9 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CCD22818.1 - 2e-48 163.8 0.0 3.5e-48 163.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 CCD22818.1 - 0.025 15.0 0.0 0.66 10.4 0.0 2.5 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FCH PF00611.18 CCD22819.1 - 1.4e-14 54.0 0.0 1.4e-14 54.0 0.0 3.1 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.16 CCD22819.1 - 1.5e-10 40.6 0.0 4e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RhoGAP PF00620.22 CCD22819.1 - 2.9e-08 33.4 0.8 5.2e-06 26.1 0.0 2.9 2 1 0 2 2 2 2 RhoGAP domain CRC_subunit PF08624.5 CCD22820.1 - 1.1e-26 93.3 1.3 1.5e-26 92.9 0.1 1.8 2 0 0 2 2 2 1 Chromatin remodelling complex Rsc7/Swp82 subunit tRNA-synt_2 PF00152.15 CCD22821.1 - 1.6e-70 237.5 0.1 2e-70 237.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CCD22821.1 - 9.8e-08 31.4 0.2 6.2e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 CCD22821.1 - 2.8e-05 23.8 0.0 6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CCD22821.1 - 0.0035 16.9 0.2 0.073 12.6 0.1 2.3 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_Me_trans PF03054.11 CCD22822.1 - 2e-110 368.7 0.1 2.3e-110 368.5 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 CCD22822.1 - 7.5e-05 21.7 0.0 0.00079 18.3 0.0 2.2 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.9 CCD22822.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Git3 PF11710.3 CCD22823.1 - 1.4e-78 263.1 11.0 2.9e-78 262.0 7.7 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 CCD22823.1 - 1.2e-25 89.1 1.4 1.2e-25 89.1 1.0 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term E1_DerP2_DerF2 PF02221.10 CCD22824.1 - 1.6e-24 86.6 0.1 1.9e-24 86.4 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 CCD22824.1 - 0.0025 17.8 0.0 0.0032 17.4 0.0 1.2 1 0 0 1 1 1 1 ML-like domain CHCH PF06747.8 CCD22825.1 - 0.00011 22.0 0.2 0.00015 21.6 0.1 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CCD22825.1 - 0.0058 16.3 0.9 0.0069 16.1 0.6 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like PAPS_reduct PF01507.14 CCD22826.1 - 1.3e-35 122.7 0.0 1.8e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family DUF3730 PF12530.3 CCD22826.1 - 0.0033 17.3 0.0 0.0053 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3730) Fib_alpha PF08702.5 CCD22827.1 - 0.22 11.6 4.7 0.73 9.9 3.2 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family LAGLIDADG_1 PF00961.14 CCD22827.1 - 1.9 9.0 10.2 0.13 12.8 2.0 2.6 2 1 1 3 3 3 0 LAGLIDADG endonuclease zf-met PF12874.2 CCD22828.1 - 3.8e-06 26.9 2.1 8.9e-06 25.7 1.5 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF3505 PF12013.3 CCD22828.1 - 0.0097 16.1 0.4 0.017 15.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3505) zf-C2H2_2 PF12756.2 CCD22828.1 - 0.018 15.1 0.2 0.032 14.3 0.1 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 CCD22828.1 - 0.073 12.6 0.2 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 U1 zinc finger SIR2 PF02146.12 CCD22829.1 - 2.9e-65 219.3 0.0 5.7e-65 218.3 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 CCD22829.1 - 2.3e-63 212.3 1.0 4.6e-63 211.3 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 CCD22829.1 - 0.00037 20.2 0.0 0.76 9.5 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain HLH PF00010.21 CCD22830.1 - 1e-16 60.3 0.0 3.5e-16 58.6 0.0 1.8 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF904 PF06005.7 CCD22830.1 - 0.16 12.2 2.7 0.57 10.5 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF904) NARP1 PF12569.3 CCD22831.1 - 1.7e-115 386.7 14.8 2.1e-83 280.8 0.7 3.4 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 CCD22831.1 - 2e-14 53.8 0.1 0.0033 18.0 0.0 5.7 5 1 0 6 6 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCD22831.1 - 2.1e-14 53.5 2.9 0.022 15.0 0.0 6.2 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 CCD22831.1 - 7.4e-12 44.2 8.8 0.0088 15.8 0.0 7.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCD22831.1 - 3.2e-11 42.7 7.0 0.044 13.4 0.0 5.5 6 0 0 6 6 5 4 TPR repeat TPR_14 PF13428.1 CCD22831.1 - 8.8e-11 41.4 2.0 0.058 14.0 0.0 7.5 8 1 1 9 9 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CCD22831.1 - 5.7e-09 36.0 10.5 1.2e-05 25.2 0.3 4.5 5 0 0 5 5 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CCD22831.1 - 7.1e-06 25.8 6.9 0.089 12.7 0.4 6.1 3 2 3 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCD22831.1 - 0.00021 20.7 9.5 0.062 12.9 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCD22831.1 - 0.00023 21.1 9.2 9.9 6.6 0.1 7.1 7 0 0 7 7 7 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCD22831.1 - 0.0011 18.7 6.1 4.1 7.3 0.0 4.5 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 CCD22831.1 - 0.0016 18.0 14.3 0.47 10.3 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCD22831.1 - 0.019 15.4 8.6 0.66 10.5 0.0 6.8 10 0 0 10 10 6 0 Tetratricopeptide repeat Rapsyn_N PF10579.4 CCD22831.1 - 0.042 13.6 0.1 0.77 9.6 0.0 2.8 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region TPR_10 PF13374.1 CCD22831.1 - 0.092 12.7 0.0 7 6.7 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat PseudoU_synth_2 PF00849.17 CCD22832.1 - 3.1e-34 118.1 1.2 1.1e-33 116.4 0.0 2.1 2 0 0 2 2 2 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.17 CCD22832.1 - 3.9e-17 61.7 0.1 9.6e-17 60.5 0.0 1.7 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region PQQ PF01011.16 CCD22832.1 - 0.00032 20.0 0.1 0.00071 18.9 0.1 1.6 1 0 0 1 1 1 1 PQQ enzyme repeat Metallophos PF00149.23 CCD22833.1 - 6.5e-43 146.4 0.2 8.2e-43 146.1 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCD22833.1 - 0.0038 17.0 0.0 0.0066 16.2 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DIL PF01843.14 CCD22833.1 - 0.12 12.3 0.1 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 DIL domain PRP38 PF03371.10 CCD22834.1 - 2.3e-49 167.3 1.2 2.9e-49 167.0 0.8 1.0 1 0 0 1 1 1 1 PRP38 family DUF3143 PF11341.3 CCD22834.1 - 0.11 12.4 0.2 0.31 10.9 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3143) Prefoldin PF02996.12 CCD22836.1 - 2.6e-37 127.1 1.0 3.6e-37 126.6 0.7 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CCD22836.1 - 0.0018 17.9 3.3 0.0045 16.7 0.1 2.4 1 1 1 2 2 2 1 Prefoldin subunit WEMBL PF05701.6 CCD22836.1 - 0.01 14.3 2.3 0.013 13.9 1.4 1.4 1 1 0 1 1 1 0 Weak chloroplast movement under blue light DUF4476 PF14771.1 CCD22836.1 - 0.031 14.3 0.4 0.096 12.7 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4476) SlyX PF04102.7 CCD22836.1 - 0.19 12.1 1.0 1.1 9.6 0.0 2.6 3 0 0 3 3 3 0 SlyX PP_M1 PF03012.9 CCD22836.1 - 0.3 10.3 3.3 0.16 11.2 0.2 1.8 2 0 0 2 2 2 0 Phosphoprotein Pox_A_type_inc PF04508.7 CCD22836.1 - 0.6 10.0 4.5 33 4.6 0.2 3.9 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat DUF1664 PF07889.7 CCD22836.1 - 0.79 9.5 3.0 3.7 7.3 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMPIT PF07851.8 CCD22836.1 - 2.6 7.0 4.9 1.2 8.1 0.7 1.9 2 0 0 2 2 2 0 TMPIT-like protein SUN PF03856.8 CCD22837.1 - 3.1e-79 265.7 20.6 4e-79 265.4 14.3 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF336 PF03928.9 CCD22838.1 - 2.2e-20 72.7 0.0 2.9e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) zf-CCCH_2 PF14608.1 CCD22838.1 - 0.48 10.5 2.9 2.3 8.3 0.4 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type NatB_MDM20 PF09797.4 CCD22840.1 - 8.5e-64 215.5 7.9 8.5e-64 215.5 5.5 2.0 2 1 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit Peptidase_S10 PF00450.17 CCD22841.1 - 2e-124 415.9 0.0 2.5e-124 415.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CCD22841.1 - 0.0061 16.4 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Mob_Pre PF01076.14 CCD22841.1 - 0.24 11.0 0.5 0.36 10.4 0.4 1.2 1 0 0 1 1 1 0 Plasmid recombination enzyme RasGAP PF00616.14 CCD22842.1 - 2e-36 125.4 1.4 5.2e-36 124.1 0.1 2.5 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF3321 PF11968.3 CCD22843.1 - 1.1e-77 260.5 0.0 1.7e-77 259.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 CCD22843.1 - 4.1e-05 23.3 0.0 6.7e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DEAD PF00270.24 CCD22844.1 - 1.5e-37 128.6 0.4 7.2e-37 126.4 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD22844.1 - 1.2e-24 85.9 0.0 3.9e-23 81.0 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD22844.1 - 0.0027 17.5 0.2 0.0027 17.5 0.1 2.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit eRF1_2 PF03464.10 CCD22845.1 - 4.6e-45 153.1 0.1 8.3e-45 152.3 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CCD22845.1 - 1.9e-38 131.2 0.2 3.9e-38 130.1 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CCD22845.1 - 3.6e-29 100.9 0.0 6.9e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 PAN_3 PF08277.7 CCD22846.1 - 0.22 11.1 1.3 0.64 9.6 0.4 2.0 2 0 0 2 2 2 0 PAN-like domain ADH_N PF08240.7 CCD22847.1 - 3.9e-31 107.0 0.5 9e-31 105.8 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCD22847.1 - 5.7e-30 103.5 0.4 8.5e-30 102.9 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCD22847.1 - 6.7e-05 23.7 0.0 0.00019 22.3 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ribosomal_S9 PF00380.14 CCD22848.1 - 6.3e-38 129.7 0.1 1e-37 129.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Erythro-docking PF09277.6 CCD22848.1 - 0.042 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Erythronolide synthase, docking RibD_C PF01872.12 CCD22849.1 - 1.3e-40 139.1 0.0 1.4e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain RNA_pol_Rpb5_C PF01191.14 CCD22850.1 - 4.6e-34 115.8 0.5 1e-33 114.7 0.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CCD22850.1 - 1.7e-33 114.8 1.1 3.3e-33 113.9 0.8 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Sof1 PF04158.9 CCD22850.1 - 0.026 14.5 0.2 0.049 13.6 0.2 1.4 1 0 0 1 1 1 0 Sof1-like domain Mrr_cat PF04471.7 CCD22850.1 - 0.032 14.0 0.0 0.11 12.3 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease Prp19_bind PF06991.6 CCD22851.1 - 1.9e-08 33.9 16.0 2.2e-08 33.7 11.1 1.0 1 0 0 1 1 1 1 Splicing factor, Prp19-binding domain DUF2222 PF09984.4 CCD22851.1 - 0.01 15.3 0.7 0.37 10.2 0.0 2.3 1 1 1 2 2 2 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) DUF1980 PF09323.5 CCD22851.1 - 1.1 9.0 7.2 3.9 7.1 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CAF-1_p150 PF11600.3 CCD22851.1 - 3.7 6.8 16.8 0.37 10.1 6.8 2.0 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Suc_Fer-like PF06999.7 CCD22852.1 - 1.4e-55 188.8 0.0 1.7e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Phospholip_A2_3 PF09056.6 CCD22852.1 - 0.04 14.1 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic phospholipase A2 Fungal_trans PF04082.13 CCD22853.1 - 1.7e-08 33.6 9.0 1.7e-08 33.6 6.3 2.9 4 0 0 4 4 4 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD22853.1 - 6.3e-08 32.4 13.5 1.5e-07 31.1 9.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 CCD22854.1 - 8.9e-44 149.4 0.0 1.1e-43 149.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family IF2_N PF04760.10 CCD22854.1 - 0.018 14.7 0.0 0.06 12.9 0.0 2.0 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region PQ-loop PF04193.9 CCD22856.1 - 1.1e-38 130.6 13.6 1.6e-19 69.1 1.3 2.8 2 0 0 2 2 2 2 PQ loop repeat SARA PF11409.3 CCD22856.1 - 0.045 13.6 0.7 0.082 12.8 0.5 1.3 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) Vps52 PF04129.7 CCD22857.1 - 2.4e-134 448.6 26.1 2.1e-123 412.5 13.4 2.0 2 0 0 2 2 2 2 Vps52 / Sac2 family BUD22 PF09073.5 CCD22857.1 - 0.1 11.6 2.1 0.17 10.9 1.5 1.3 1 0 0 1 1 1 0 BUD22 NOA36 PF06524.7 CCD22857.1 - 2.3 7.4 8.0 5.2 6.2 5.5 1.5 1 0 0 1 1 1 0 NOA36 protein YL1 PF05764.8 CCD22858.1 - 2.6e-54 184.3 44.3 2.6e-54 184.3 30.7 2.8 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 CCD22858.1 - 4.1e-13 48.6 0.7 7.3e-13 47.8 0.5 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Snf7 PF03357.16 CCD22859.1 - 6.5e-39 133.0 24.1 8.5e-39 132.6 16.7 1.2 1 0 0 1 1 1 1 Snf7 YlqD PF11068.3 CCD22859.1 - 0.011 15.7 14.2 0.011 15.7 9.8 2.4 1 1 1 2 2 2 0 YlqD protein Exonuc_VII_L PF02601.10 CCD22859.1 - 0.011 14.9 12.6 0.014 14.6 8.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Fmp27_WPPW PF10359.4 CCD22859.1 - 0.014 13.7 15.9 0.0058 15.1 7.9 1.9 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain SMC_Nse1 PF07574.8 CCD22859.1 - 0.058 13.0 8.7 0.088 12.4 6.0 1.3 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex Atg14 PF10186.4 CCD22859.1 - 0.1 11.5 16.4 0.15 10.9 11.4 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3969 PF13108.1 CCD22859.1 - 0.38 10.4 8.1 0.21 11.2 3.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3969) TA0956 PF11513.3 CCD22859.1 - 0.64 10.1 3.3 0.61 10.1 0.8 2.0 1 1 1 2 2 2 0 Thermoplasma acidophilum protein TA0956 Mnd1 PF03962.10 CCD22859.1 - 0.74 9.4 17.3 0.24 11.0 5.4 2.3 1 1 2 3 3 3 0 Mnd1 family DUF771 PF05595.6 CCD22859.1 - 1 9.3 5.2 0.33 10.8 0.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF771) Serine_rich PF08824.5 CCD22859.1 - 1.7 8.3 16.9 0.45 10.2 7.6 2.6 1 1 1 2 2 2 0 Serine rich protein interaction domain Reo_sigmaC PF04582.7 CCD22859.1 - 1.9 7.6 13.4 1.2 8.2 0.7 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 CCD22859.1 - 1.9 8.3 21.9 0.091 12.6 10.2 2.2 1 1 1 2 2 2 0 Tropomyosin like FlaC_arch PF05377.6 CCD22859.1 - 3.9 7.4 11.1 2.9 7.8 0.1 4.0 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) CorA PF01544.13 CCD22859.1 - 5.2 6.0 12.6 8.9 5.2 7.2 2.1 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Toxin_52 PF15605.1 CCD22859.1 - 6.2 6.7 16.5 3.7 7.4 0.7 3.3 1 1 2 3 3 3 0 Putative toxin 52 DUF342 PF03961.8 CCD22859.1 - 7 4.9 14.5 1.5 7.1 6.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) IL2 PF00715.12 CCD22859.1 - 7.3 6.3 9.8 5.8 6.6 5.6 1.6 1 1 1 2 2 2 0 Interleukin 2 DHBP_synthase PF00926.14 CCD22860.1 - 4.5e-82 273.9 0.0 5.1e-82 273.8 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase WD40 PF00400.27 CCD22861.1 - 0.0002 21.1 0.1 0.0029 17.4 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Sld5 PF05916.6 CCD22862.1 - 4.7e-16 59.0 1.9 9.8e-16 57.9 0.6 2.2 2 1 0 2 2 2 1 GINS complex protein Vhr1 PF04001.8 CCD22862.1 - 0.03 14.2 0.9 0.089 12.7 0.2 2.0 2 0 0 2 2 2 0 Transcription factor Vhr1 CPL PF08144.6 CCD22864.1 - 1.5e-18 67.0 0.2 9.7e-17 61.1 0.0 3.2 3 0 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.14 CCD22864.1 - 0.003 16.9 5.4 9.5 5.9 0.0 5.8 6 0 0 6 6 6 1 Pumilio-family RNA binding repeat RepA_N PF06970.6 CCD22864.1 - 0.0049 16.6 0.0 0.016 15.0 0.0 1.9 1 0 0 1 1 1 1 Replication initiator protein A (RepA) N-terminus DUF4253 PF14062.1 CCD22864.1 - 0.094 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) FAD-oxidase_C PF02913.14 CCD22864.1 - 0.13 11.5 1.1 0.26 10.5 0.0 2.0 3 0 0 3 3 3 0 FAD linked oxidases, C-terminal domain BUD22 PF09073.5 CCD22864.1 - 1.4 7.8 34.2 2.7 6.9 23.7 1.4 1 0 0 1 1 1 0 BUD22 Sugar_tr PF00083.19 CCD22865.1 - 2.4e-146 487.8 34.7 3.1e-146 487.4 24.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD22865.1 - 1.8e-31 109.1 38.3 1.6e-30 105.9 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCD22865.1 - 5e-06 25.0 6.9 5e-06 25.0 4.8 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CCD22865.1 - 0.00069 17.8 0.4 0.00069 17.8 0.3 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector Sec20 PF03908.8 CCD22866.1 - 1.3e-31 108.1 1.8 1.3e-31 108.1 1.2 2.5 3 0 0 3 3 3 1 Sec20 Mucin PF01456.12 CCD22866.1 - 0.002 17.9 3.7 0.002 17.9 2.6 2.6 2 1 0 2 2 2 1 Mucin-like glycoprotein AAA_23 PF13476.1 CCD22866.1 - 4.5 7.5 22.9 0.76 10.0 1.1 2.6 2 1 0 2 2 2 0 AAA domain Vps39_2 PF10367.4 CCD22867.1 - 0.19 11.9 5.7 2.6 8.2 0.1 4.0 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Ribosomal_L18_c PF14204.1 CCD22868.1 - 0.02 15.4 0.7 0.02 15.4 0.5 2.0 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Hist_deacetyl PF00850.14 CCD22868.1 - 0.047 12.9 0.5 0.11 11.7 0.3 1.8 1 1 0 1 1 1 0 Histone deacetylase domain Complex1_LYR PF05347.10 CCD22869.1 - 0.015 15.0 0.5 0.024 14.4 0.4 1.3 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCD22869.1 - 0.036 14.2 0.5 0.053 13.7 0.4 1.2 1 0 0 1 1 1 0 Complex1_LYR-like Phage_CRI PF05144.9 CCD22869.1 - 0.069 12.2 0.6 0.071 12.2 0.4 1.1 1 0 0 1 1 1 0 Phage replication protein CRI HlyIII PF03006.15 CCD22870.1 - 1.2e-48 165.5 24.3 1.4e-48 165.2 16.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related ERG4_ERG24 PF01222.12 CCD22871.1 - 9e-165 548.3 19.0 1e-164 548.2 13.2 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CCD22871.1 - 9.3e-07 28.3 1.0 9.3e-07 28.3 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) CTP_transf_1 PF01148.15 CCD22872.1 - 4.4e-75 252.6 25.7 5.5e-75 252.3 17.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2370 PF10176.4 CCD22872.1 - 0.19 11.0 0.9 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Pkinase PF00069.20 CCD22873.1 - 7.9e-65 218.5 0.0 1.5e-64 217.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22873.1 - 5.2e-32 110.9 0.0 3.7e-31 108.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD22873.1 - 0.0033 16.4 0.2 0.016 14.1 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 CCD22873.1 - 1.3 9.5 10.7 0.53 10.8 4.9 2.4 2 1 0 2 2 2 0 Protein kinase C terminal domain ADH_zinc_N PF00107.21 CCD22874.1 - 1.2e-06 28.0 0.0 2.2e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YchF-GTPase_C PF06071.8 CCD22875.1 - 5.6e-36 122.2 0.1 1.4e-35 120.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CCD22875.1 - 3.3e-12 46.4 0.0 1.5e-11 44.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 CCD22875.1 - 6.6e-05 22.6 0.0 0.00015 21.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain SecA_PP_bind PF01043.15 CCD22875.1 - 0.022 15.1 0.4 3.3 8.1 0.0 2.3 2 0 0 2 2 2 0 SecA preprotein cross-linking domain FeoB_N PF02421.13 CCD22875.1 - 0.024 13.9 0.0 0.051 12.8 0.0 1.5 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF3236 PF11576.3 CCD22875.1 - 0.13 11.6 0.7 0.35 10.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) SCO1-SenC PF02630.9 CCD22876.1 - 1.7e-62 210.0 0.0 2.8e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.1 CCD22876.1 - 2.3e-05 24.4 0.6 0.00019 21.4 0.0 2.5 3 0 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 CCD22876.1 - 4.2e-05 23.2 0.2 0.0028 17.3 0.0 2.8 2 1 0 2 2 2 1 AhpC/TSA family Chitin_synth_1 PF01644.12 CCD22877.1 - 3.4e-77 257.8 1.1 5.3e-77 257.1 0.8 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 CCD22877.1 - 2.6e-25 88.8 2.7 2e-19 69.4 0.0 3.1 2 1 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.6 CCD22877.1 - 8.2e-25 86.3 0.0 3.2e-24 84.4 0.0 2.1 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.1 CCD22877.1 - 6.6e-11 42.4 0.0 7.7e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 CCD22877.1 - 1.4e-10 41.2 0.3 1.4e-10 41.2 0.2 2.3 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 CCD22878.1 - 4.8e-290 962.4 0.1 7.7e-290 961.7 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CCD22878.1 - 2.2e-17 63.3 0.7 8.1e-17 61.5 0.5 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCD22878.1 - 4.7e-14 52.7 0.0 4.7e-12 46.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CCD22878.1 - 2.3e-05 24.1 0.1 0.00058 19.6 0.0 2.8 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 CCD22878.1 - 0.0007 18.9 0.0 0.0039 16.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 CCD22878.1 - 0.00075 19.2 0.0 0.016 14.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 Macro PF01661.16 CCD22879.1 - 4e-26 91.2 0.0 4.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 Macro domain Transp_cyt_pur PF02133.10 CCD22880.1 - 8.5e-176 584.8 35.5 9.9e-176 584.6 24.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1648 PF07853.6 CCD22880.1 - 0.0044 16.4 1.1 0.017 14.5 0.7 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1648) GalKase_gal_bdg PF10509.4 CCD22881.1 - 6.5e-22 76.5 0.0 1.2e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CCD22881.1 - 1e-15 57.5 0.2 2.2e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain Aldose_epim PF01263.15 CCD22882.1 - 1.2e-78 264.2 0.4 1.6e-78 263.8 0.3 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.16 CCD22882.1 - 2.9e-52 177.4 0.0 4.6e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CCD22882.1 - 5.4e-23 80.6 0.1 1.4e-22 79.4 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 CCD22882.1 - 3.5e-16 58.9 0.0 1.3e-14 53.8 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CCD22882.1 - 3.5e-15 55.4 0.0 6.7e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CCD22882.1 - 4.6e-11 42.1 0.0 7e-11 41.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 CCD22882.1 - 8.1e-10 38.8 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CCD22882.1 - 2.7e-08 33.0 0.0 9.8e-08 31.2 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 CCD22882.1 - 9.6e-08 31.8 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCD22882.1 - 5.6e-06 26.4 0.0 9.6e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding AAA PF00004.24 CCD22883.1 - 1e-41 142.2 0.0 1.7e-41 141.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCD22883.1 - 4.9e-07 29.9 0.5 0.0015 18.6 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 CCD22883.1 - 5.1e-06 25.6 0.0 8.6e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 CCD22883.1 - 8.4e-06 25.8 0.0 2.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCD22883.1 - 1.7e-05 24.5 0.1 6.8e-05 22.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCD22883.1 - 7.3e-05 22.8 0.0 0.0019 18.2 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 CCD22883.1 - 0.00028 20.0 0.0 0.00053 19.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCD22883.1 - 0.00092 19.1 0.0 0.002 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCD22883.1 - 0.0012 18.8 0.3 0.0036 17.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCD22883.1 - 0.0026 18.5 0.2 0.0073 17.1 0.1 1.9 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CCD22883.1 - 0.0055 16.1 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CCD22883.1 - 0.0057 16.3 0.3 0.012 15.3 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain Zeta_toxin PF06414.7 CCD22883.1 - 0.0069 15.4 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 CCD22883.1 - 0.0078 15.8 0.0 0.022 14.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CCD22883.1 - 0.0083 16.4 0.2 0.023 15.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain PhoH PF02562.11 CCD22883.1 - 0.0092 15.2 0.4 0.16 11.2 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 CCD22883.1 - 0.0096 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CCD22883.1 - 0.011 14.6 0.0 0.031 13.1 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain TIP49 PF06068.8 CCD22883.1 - 0.013 14.2 0.0 0.029 13.0 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus KaiC PF06745.8 CCD22883.1 - 0.016 14.2 0.2 0.34 10.0 0.1 2.4 1 1 0 2 2 2 0 KaiC NTPase_1 PF03266.10 CCD22883.1 - 0.022 14.4 0.1 0.25 11.0 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_25 PF13481.1 CCD22883.1 - 0.024 14.0 2.7 0.15 11.4 0.3 2.5 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.17 CCD22883.1 - 0.024 14.8 0.0 0.058 13.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CCD22883.1 - 0.026 14.2 0.2 0.27 10.8 0.1 2.2 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.16 CCD22883.1 - 0.039 13.1 0.1 0.082 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CCD22883.1 - 0.041 13.4 0.2 0.11 12.0 0.2 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 CCD22883.1 - 0.09 11.7 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PP2C PF00481.16 CCD22884.1 - 4e-68 229.5 0.3 5.1e-53 180.0 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C Med2 PF11214.3 CCD22885.1 - 5.9e-31 106.6 15.1 5.9e-31 106.6 10.4 4.0 2 2 2 4 4 4 1 Mediator complex subunit 2 DUF77 PF01910.12 CCD22886.1 - 3.8e-29 100.2 0.1 4.3e-29 100.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 YugN PF08868.5 CCD22886.1 - 0.13 11.8 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 YugN-like family Histone PF00125.19 CCD22887.1 - 3.6e-21 75.0 0.3 5.7e-21 74.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCD22887.1 - 1e-05 25.4 0.1 2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CCD22887.1 - 0.0017 18.5 0.0 0.0034 17.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 CCD22887.1 - 0.033 12.8 6.0 0.04 12.5 4.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Dicty_REP PF05086.7 CCD22887.1 - 1.3 6.6 8.8 1.4 6.5 6.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Histone PF00125.19 CCD22888.1 - 6.3e-26 90.2 0.0 8.8e-26 89.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCD22888.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF155 PF02582.9 CCD22889.1 - 1.2e-61 207.6 2.6 2.2e-61 206.7 1.8 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 CCD22889.1 - 0.019 15.1 0.0 0.073 13.2 0.0 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 HMG_box PF00505.14 CCD22890.1 - 3.1e-12 46.5 0.0 1e-11 44.9 0.0 2.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCD22890.1 - 1.1e-10 41.7 0.0 3e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 HMG-box domain F-box-like PF12937.2 CCD22891.1 - 2.4e-06 27.1 0.5 8.6e-06 25.3 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCD22891.1 - 0.00014 21.4 0.9 0.00014 21.4 0.6 3.1 3 0 0 3 3 3 1 F-box domain Bac_rhodopsin PF01036.13 CCD22892.1 - 9.1e-25 87.2 9.9 1.1e-24 86.9 6.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Wzy_C PF04932.10 CCD22892.1 - 0.028 14.1 0.4 0.028 14.1 0.3 1.9 2 0 0 2 2 2 0 O-Antigen ligase EmrE PF13536.1 CCD22892.1 - 0.086 13.0 0.3 0.086 13.0 0.2 2.2 2 0 0 2 2 2 0 Multidrug resistance efflux transporter DUF1286 PF06939.6 CCD22892.1 - 0.58 10.3 4.5 0.34 11.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1286) DUF1772 PF08592.6 CCD22892.1 - 1.3 8.7 7.4 1.1 9.0 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) ABC2_membrane_5 PF13346.1 CCD22892.1 - 2.8 7.1 13.6 4.3 6.5 0.5 2.1 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF4131 PF13567.1 CCD22892.1 - 8.7 5.7 9.7 0.11 11.9 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cellulase PF00150.13 CCD22893.1 - 1.1e-09 37.8 2.6 1.1e-09 37.8 1.8 1.9 2 1 1 3 3 3 1 Cellulase (glycosyl hydrolase family 5) Lzipper-MIP1 PF14389.1 CCD22894.1 - 0.00031 20.8 2.3 0.0012 18.9 1.6 2.1 1 1 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 PhoU PF01895.14 CCD22894.1 - 3.1 8.2 7.0 2.5 8.6 1.4 2.7 1 1 2 3 3 3 0 PhoU domain UCH PF00443.24 CCD22895.1 - 2.5e-46 157.9 0.0 1e-45 155.9 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCD22895.1 - 4.9e-22 78.7 8.3 1.2e-20 74.1 5.8 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCD22895.1 - 1.2e-19 70.1 5.6 1.2e-19 70.1 3.8 2.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 CCD22895.1 - 4.1e-12 45.5 0.0 1e-07 31.5 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain Pox_P35 PF03213.9 CCD22896.1 - 0.084 11.8 0.2 0.097 11.6 0.1 1.0 1 0 0 1 1 1 0 Poxvirus P35 protein DUF3317 PF11779.3 CCD22896.1 - 1.1 8.6 7.5 1.5 8.3 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) ORC2 PF04084.9 CCD22897.1 - 9.4e-100 333.6 1.8 1.5e-99 332.9 1.2 1.3 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Mem_trans PF03547.13 CCD22897.1 - 0.014 13.6 0.0 0.21 9.8 0.0 2.5 2 1 0 2 2 2 0 Membrane transport protein AT_hook PF02178.14 CCD22897.1 - 0.021 14.4 18.6 0.57 10.0 3.1 3.4 2 0 0 2 2 2 0 AT hook motif FtsJ PF01728.14 CCD22898.1 - 1.4e-64 217.4 0.1 1.9e-64 216.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase CbiA PF01656.18 CCD22898.1 - 0.077 12.3 0.1 0.22 10.9 0.0 1.7 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain zf-RING_2 PF13639.1 CCD22899.1 - 1e-12 47.6 7.2 1.9e-12 46.7 5.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCD22899.1 - 8.3e-09 35.4 6.0 1.8e-08 34.3 4.1 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCD22899.1 - 1.7e-05 24.5 2.6 2.1e-05 24.2 1.2 1.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CCD22899.1 - 2.1e-05 24.0 6.7 2.1e-05 24.0 4.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCD22899.1 - 4.6e-05 23.0 4.3 8.7e-05 22.1 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CCD22899.1 - 0.00048 20.0 8.1 0.0011 18.8 3.7 2.6 2 1 0 2 2 2 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 CCD22899.1 - 0.00059 19.8 8.0 0.00059 19.8 5.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCD22899.1 - 0.0012 18.5 5.3 0.0012 18.5 3.7 1.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 CCD22899.1 - 0.0019 17.8 1.2 0.0085 15.7 1.0 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCD22899.1 - 0.25 11.2 7.5 1.1 9.2 5.3 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING UPF0547 PF10571.4 CCD22899.1 - 4.2 7.1 9.4 1.4 8.6 0.9 2.7 3 1 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-P11 PF03854.9 CCD22899.1 - 4.7 6.7 11.3 1.6 8.2 5.2 2.1 2 1 0 2 2 2 0 P-11 zinc finger zf-H2C2_2 PF13465.1 CCD22901.1 - 7.1e-06 26.0 3.7 7.1e-06 26.0 2.5 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCD22901.1 - 0.00039 20.5 13.4 0.037 14.3 4.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCD22901.1 - 0.0033 17.6 19.6 0.012 15.8 2.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type BAT2_N PF07001.6 CCD22901.1 - 0.022 15.1 1.2 0.044 14.1 0.8 1.6 1 1 0 1 1 1 0 BAT2 N-terminus zf-met PF12874.2 CCD22901.1 - 3.6 7.9 10.0 1.2 9.3 0.8 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-RING-like PF08746.6 CCD22901.1 - 4 7.5 11.1 0.072 13.1 2.0 2.1 2 0 0 2 2 2 0 RING-like domain SRP1_TIP1 PF00660.12 CCD22902.1 - 8.1e-35 118.7 0.8 2.1e-34 117.4 0.5 1.6 1 0 0 1 1 1 1 Seripauperin and TIP1 family PIR PF00399.14 CCD22902.1 - 6.6e-06 25.2 1.1 4.2e-05 22.7 0.7 2.5 1 0 0 1 1 1 1 Yeast PIR protein repeat DUF2201_N PF13203.1 CCD22902.1 - 0.012 14.8 0.3 0.014 14.5 0.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain TFIIA PF03153.8 CCD22902.1 - 0.78 9.5 3.5 0.99 9.2 2.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 CCD22902.1 - 2.8 6.1 9.8 3.3 5.8 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 CCD22902.1 - 3.7 6.4 8.4 4.5 6.2 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain SWI-SNF_Ssr4 PF08549.5 CCD22902.1 - 7 4.8 10.4 8.1 4.6 7.2 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Med3 PF11593.3 CCD22902.1 - 7.8 5.6 19.7 9.6 5.3 13.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AA_permease PF00324.16 CCD22903.1 - 1.2e-126 422.8 33.6 1.5e-126 422.5 23.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD22903.1 - 5.8e-39 133.8 31.3 7.9e-39 133.3 21.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCD22904.1 - 2.7e-123 411.8 33.1 3.1e-123 411.6 23.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD22904.1 - 1.8e-37 128.9 35.5 2.1e-37 128.7 24.6 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 CCD22904.1 - 1.8e-05 23.5 22.6 0.00011 20.9 11.3 2.5 2 0 0 2 2 2 2 Spore germination protein SNF2_N PF00176.18 CCD22905.1 - 6.4e-61 205.7 0.0 1.1e-60 205.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCD22905.1 - 3.7e-10 39.5 0.0 1.1e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD22905.1 - 8.4e-10 38.7 0.0 3.7e-09 36.6 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCD22905.1 - 1.5e-09 37.5 0.3 2.9e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 CCD22905.1 - 1.5e-08 33.8 9.6 2.7e-08 32.9 2.5 3.3 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Peptidase_M28 PF04389.12 CCD22906.1 - 2.4e-30 105.5 0.1 4e-29 101.6 0.0 2.7 3 0 0 3 3 3 1 Peptidase family M28 Peptidase_M20 PF01546.23 CCD22906.1 - 0.0008 18.9 0.0 0.00099 18.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 CCD22906.1 - 0.00081 18.2 0.0 0.0024 16.7 0.0 1.7 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase DUF4451 PF14616.1 CCD22907.1 - 1.2e-07 31.5 0.2 3e-06 26.9 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF4451) zf-C2H2 PF00096.21 CCD22908.1 - 4.9e-10 39.1 15.6 1e-05 25.5 2.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCD22908.1 - 4.9e-08 32.8 9.5 5.5e-07 29.5 0.2 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCD22908.1 - 3.3e-06 27.0 9.6 0.0047 17.1 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CCD22908.1 - 9.2e-06 25.6 5.4 0.00096 19.2 1.0 2.7 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCD22908.1 - 0.001 19.1 5.4 0.0013 18.8 0.5 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCD22908.1 - 0.12 12.2 2.0 1.3 9.0 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CCD22908.1 - 0.26 11.6 7.8 5.8 7.3 0.4 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 CCD22908.1 - 0.3 11.2 3.2 0.3 11.2 0.4 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 CCD22908.1 - 1.1 9.1 8.2 0.087 12.5 1.4 2.1 2 0 0 2 2 2 0 BED zinc finger Dfp1_Him1_M PF08630.5 CCD22909.1 - 3.5e-16 59.1 1.5 2.9e-11 43.2 0.2 2.8 1 1 1 2 2 2 2 Dfp1/Him1, central region Utp11 PF03998.8 CCD22910.1 - 0.008 16.0 2.0 0.0096 15.7 1.4 1.1 1 0 0 1 1 1 1 Utp11 protein Daxx PF03344.10 CCD22910.1 - 0.052 12.0 7.2 0.061 11.8 5.0 1.0 1 0 0 1 1 1 0 Daxx Family vMSA PF00695.14 CCD22910.1 - 0.16 11.1 0.2 0.2 10.8 0.2 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus UQ_con PF00179.21 CCD22911.1 - 1.2e-42 144.6 0.2 1.8e-42 144.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCD22911.1 - 6.6e-05 22.6 0.0 0.00023 20.9 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B Recep_L_domain PF01030.19 CCD22912.1 - 6.6e-08 32.5 6.1 0.056 13.4 1.0 4.5 1 1 2 3 3 3 3 Receptor L domain LRR_9 PF14580.1 CCD22912.1 - 0.00066 19.2 0.9 0.003 17.1 0.1 2.2 1 1 0 2 2 2 1 Leucine-rich repeat DUF4339 PF14237.1 CCD22912.1 - 0.0019 17.7 0.0 0.083 12.4 0.0 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF4339) REC114-like PF15165.1 CCD22912.1 - 0.1 12.2 4.7 0.12 12.0 0.7 2.1 2 0 0 2 2 2 0 Meiotic recombination protein REC114-like PCI PF01399.22 CCD22913.1 - 8.5e-06 26.0 5.0 0.00016 21.9 0.0 3.1 3 0 0 3 3 3 2 PCI domain AAA PF00004.24 CCD22914.1 - 1.8e-52 176.9 0.0 9.6e-38 129.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CCD22914.1 - 7e-15 54.7 0.0 2.5e-14 53.0 0.0 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 CCD22914.1 - 5.6e-10 39.4 0.2 0.00083 19.5 0.2 3.3 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CCD22914.1 - 1.3e-09 37.6 0.3 0.0018 17.9 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain CDC48_2 PF02933.12 CCD22914.1 - 1.4e-09 37.4 0.8 4.6e-09 35.7 0.1 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_17 PF13207.1 CCD22914.1 - 4e-09 37.3 0.0 0.003 18.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 CCD22914.1 - 9.7e-09 34.4 0.1 0.00047 18.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 CCD22914.1 - 1.3e-08 35.0 0.0 0.0056 16.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 CCD22914.1 - 1e-07 31.8 0.0 0.017 15.0 0.0 3.3 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 CCD22914.1 - 1.3e-07 31.0 0.1 0.0017 17.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCD22914.1 - 1.6e-07 31.0 0.0 0.0016 18.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CCD22914.1 - 3e-07 30.0 0.1 0.022 14.1 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 CCD22914.1 - 7e-07 29.6 0.1 0.025 14.8 0.0 3.1 4 0 0 4 4 2 2 AAA domain RuvB_N PF05496.7 CCD22914.1 - 7.6e-07 28.4 0.1 0.035 13.1 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCD22914.1 - 5.2e-06 26.3 0.0 0.033 14.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 CCD22914.1 - 6.5e-06 25.5 0.0 0.009 15.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_2 PF07724.9 CCD22914.1 - 1.4e-05 25.0 0.0 0.0017 18.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 CCD22914.1 - 1.5e-05 25.0 0.0 0.12 12.5 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 CCD22914.1 - 3e-05 24.3 0.2 0.049 13.9 0.0 2.7 2 0 0 2 2 2 1 ABC transporter DUF2075 PF09848.4 CCD22914.1 - 7.6e-05 21.8 0.0 0.14 11.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 CCD22914.1 - 8.3e-05 22.3 3.0 0.053 13.1 0.0 3.5 4 1 0 4 4 3 1 NACHT domain AAA_11 PF13086.1 CCD22914.1 - 0.0001 21.9 0.0 0.1 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CCD22914.1 - 0.00011 21.3 0.0 0.068 12.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Sigma54_activat PF00158.21 CCD22914.1 - 0.00013 21.4 0.0 0.3 10.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.17 CCD22914.1 - 0.00025 19.9 0.0 0.22 10.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_25 PF13481.1 CCD22914.1 - 0.00033 20.1 6.4 0.21 10.9 0.2 4.0 2 2 1 4 4 4 1 AAA domain AAA_10 PF12846.2 CCD22914.1 - 0.00044 19.7 0.1 0.0099 15.3 0.0 2.2 2 0 0 2 2 2 1 AAA-like domain AAA_24 PF13479.1 CCD22914.1 - 0.00077 19.1 4.2 0.45 10.0 0.3 2.8 3 1 0 3 3 2 2 AAA domain AAA_3 PF07726.6 CCD22914.1 - 0.00089 18.8 0.0 0.2 11.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 CCD22914.1 - 0.0009 19.6 1.8 0.86 9.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 CCD22914.1 - 0.001 18.2 0.5 0.24 10.5 0.1 2.6 2 1 0 2 2 2 1 KaiC AAA_28 PF13521.1 CCD22914.1 - 0.0021 18.0 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.13 CCD22914.1 - 0.0023 17.5 0.0 1.1 8.8 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein ResIII PF04851.10 CCD22914.1 - 0.003 17.4 0.0 1.2 8.8 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 CCD22914.1 - 0.0036 17.0 0.5 3.9 7.1 0.0 3.3 2 1 1 3 3 3 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 CCD22914.1 - 0.0039 17.2 0.2 4.6 7.2 0.1 3.2 2 1 0 2 2 2 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CCD22914.1 - 0.0058 15.5 0.0 2.6 6.8 0.0 2.3 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Zot PF05707.7 CCD22914.1 - 0.0059 16.0 0.1 4.9 6.5 0.0 2.9 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) DEAD PF00270.24 CCD22914.1 - 0.01 15.3 0.7 24 4.3 0.0 3.8 2 2 1 4 4 4 0 DEAD/DEAH box helicase AAA_30 PF13604.1 CCD22914.1 - 0.013 15.1 0.0 4 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CCD22914.1 - 0.02 13.7 0.1 4.5 6.0 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein KTI12 PF08433.5 CCD22914.1 - 0.023 13.9 0.0 4.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 CCD22914.1 - 0.025 14.0 0.1 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 CCD22914.1 - 0.04 13.5 0.0 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 CCD22914.1 - 0.058 13.0 0.1 11 5.6 0.0 2.7 2 0 0 2 2 2 0 NTPase cobW PF02492.14 CCD22914.1 - 0.068 12.6 0.3 2.8 7.3 0.0 2.8 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CPT PF07931.7 CCD22914.1 - 0.069 12.7 0.3 6.4 6.3 0.0 2.9 3 0 0 3 3 3 0 Chloramphenicol phosphotransferase-like protein Viral_helicase1 PF01443.13 CCD22914.1 - 0.18 11.2 0.0 0.84 9.1 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Bromodomain PF00439.20 CCD22916.1 - 7.4e-17 61.0 0.3 3.8e-16 58.7 0.2 2.3 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 CCD22916.1 - 9.3e-06 25.2 0.0 4.8e-05 22.9 0.0 2.2 3 0 0 3 3 3 1 Bromodomain associated CBF PF03914.12 CCD22917.1 - 4e-45 153.2 0.3 4e-45 153.2 0.2 3.3 3 0 0 3 3 3 1 CBF/Mak21 family TEA PF01285.13 CCD22918.1 - 7.1e-29 101.2 21.2 7.1e-29 101.2 14.7 4.3 1 1 0 3 3 3 1 TEA/ATTS domain family FTHFS PF01268.14 CCD22919.1 - 1.7e-256 851.6 0.3 2.3e-256 851.1 0.2 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CCD22919.1 - 1.5e-68 228.9 0.3 1.5e-68 228.9 0.2 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CCD22919.1 - 4.4e-35 120.2 0.9 1.3e-34 118.6 0.6 1.9 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Ribosomal_L19e PF01280.15 CCD22920.1 - 1.8e-58 196.5 9.9 1.8e-58 196.5 6.9 1.8 1 1 1 2 2 2 1 Ribosomal protein L19e DUF349 PF03993.7 CCD22920.1 - 6.4 7.0 14.3 26 5.0 5.2 3.4 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) Mito_carr PF00153.22 CCD22921.1 - 4.5e-70 231.4 7.0 9e-24 83.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PsbX PF06596.6 CCD22921.1 - 2 8.1 4.7 0.87 9.3 0.9 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre X protein (PsbX) KH_1 PF00013.24 CCD22922.1 - 4.7e-32 109.4 6.8 1.7e-10 40.3 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCD22922.1 - 5.9e-24 83.2 7.4 1.3e-08 34.2 0.2 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CCD22922.1 - 9.4e-10 37.9 4.6 0.018 14.5 0.0 4.0 3 1 0 3 3 3 3 KH domain KH_4 PF13083.1 CCD22922.1 - 2e-08 33.7 0.2 0.014 15.0 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 CCD22922.1 - 7e-05 22.5 11.1 0.042 13.6 0.1 4.5 3 2 1 4 4 4 2 NusA-like KH domain Anoctamin PF04547.7 CCD22924.1 - 5.4e-37 127.5 38.6 7e-36 123.8 26.8 2.3 1 1 0 1 1 1 1 Calcium-activated chloride channel Mucin PF01456.12 CCD22924.1 - 2.3 8.0 18.3 5.4 6.7 10.8 2.8 2 0 0 2 2 2 0 Mucin-like glycoprotein Ala_racemase_N PF01168.15 CCD22925.1 - 3.9e-37 127.9 0.0 4.9e-37 127.5 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3053 PF11254.3 CCD22925.1 - 0.056 12.7 0.2 0.1 11.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) FAD_binding_1 PF00667.15 CCD22926.1 - 1.1e-30 106.7 0.0 2.4e-30 105.6 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCD22926.1 - 3.1e-26 92.0 0.0 5.5e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCD22926.1 - 2.9e-13 50.3 0.0 6.4e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.6 CCD22926.1 - 0.051 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 NrdI Flavodoxin like UCR_6-4kD PF08997.5 CCD22926.1 - 0.11 12.2 0.6 1.3 8.8 0.9 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein MFS_1 PF07690.11 CCD22927.1 - 4.4e-34 117.7 35.7 4.4e-34 117.7 24.8 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCD22927.1 - 8.5e-06 24.2 6.1 1.4e-05 23.5 4.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 CCD22927.1 - 1.1 7.2 16.6 0.0065 14.5 2.2 2.8 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PCNA_N PF00705.13 CCD22928.1 - 1.7e-51 173.0 1.7 2.7e-51 172.3 1.2 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CCD22928.1 - 3.9e-47 159.3 0.1 8.3e-47 158.2 0.0 1.5 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 CCD22928.1 - 6.5e-07 28.3 1.2 1.2e-05 24.2 0.8 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 CCD22928.1 - 0.002 17.3 0.1 0.0021 17.2 0.0 1.1 1 0 0 1 1 1 1 Rad9 FOP_dimer PF09398.5 CCD22928.1 - 0.027 14.4 0.2 0.027 14.4 0.1 1.8 2 0 0 2 2 2 0 FOP N terminal dimerisation domain zf-Tim10_DDP PF02953.10 CCD22929.1 - 7.6e-16 57.1 2.9 9.4e-16 56.8 2.0 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger TTL PF03133.10 CCD22930.1 - 2.9e-81 272.6 6.0 3.2e-81 272.4 3.2 1.6 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family SurE PF01975.12 CCD22930.1 - 3.1e-38 131.0 0.0 7.6e-38 129.7 0.0 1.6 1 1 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 CCD22930.1 - 2.8e-05 23.0 0.0 0.0078 15.0 0.0 2.5 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 CCD22930.1 - 0.0003 20.5 0.0 0.0017 18.1 0.0 2.1 1 1 1 2 2 2 1 ATP-grasp domain Nro1 PF12753.2 CCD22930.1 - 0.0071 15.3 1.8 0.0071 15.3 1.3 1.6 2 0 0 2 2 2 1 Nuclear pore complex subunit Nro1 ATPgrasp_Ter PF15632.1 CCD22930.1 - 0.14 10.9 0.0 1.5 7.5 0.0 2.3 3 0 0 3 3 3 0 ATP-grasp in the biosynthetic pathway with Ter operon RXT2_N PF08595.6 CCD22931.1 - 5.7e-36 123.5 1.4 5.7e-36 123.5 0.9 2.5 2 0 0 2 2 2 2 RXT2-like, N-terminal 4HBT_2 PF13279.1 CCD22932.1 - 2.3e-05 24.8 0.0 3.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily Pkinase PF00069.20 CCD22933.1 - 1.4e-26 93.2 0.1 3.2e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD22933.1 - 4.1e-10 39.1 0.1 2.6e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.17 CCD22933.1 - 1.1e-05 25.1 3.0 25 5.2 0.1 6.4 6 0 0 6 6 6 2 HEAT repeat ERCC4 PF02732.10 CCD22934.1 - 3.2e-08 33.4 0.6 3.2e-08 33.4 0.4 2.7 4 0 0 4 4 4 1 ERCC4 domain Fes1 PF08609.5 CCD22935.1 - 2.1e-24 85.8 0.6 2.1e-24 85.8 0.4 2.9 3 1 0 3 3 3 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 CCD22935.1 - 2.3e-05 24.5 0.4 0.00097 19.3 0.1 3.3 1 1 2 3 3 3 2 HEAT repeats IBN_N PF03810.14 CCD22935.1 - 6.6e-05 22.7 3.4 0.012 15.5 0.5 4.0 2 1 2 4 4 4 1 Importin-beta N-terminal domain CDC14 PF08045.6 CCD22935.1 - 0.00019 20.6 6.4 0.00042 19.5 4.5 1.7 1 1 0 1 1 1 1 Cell division control protein 14, SIN component DUF3361 PF11841.3 CCD22935.1 - 0.0028 17.4 1.4 0.0065 16.1 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) UME PF08064.8 CCD22935.1 - 0.018 15.0 1.6 0.068 13.1 0.1 2.4 2 1 0 2 2 2 0 UME (NUC010) domain V-ATPase_H_C PF11698.3 CCD22935.1 - 0.047 13.6 3.2 0.29 11.0 0.5 2.5 1 1 2 3 3 3 0 V-ATPase subunit H HEAT_EZ PF13513.1 CCD22935.1 - 0.058 13.8 0.2 0.53 10.8 0.0 2.8 3 1 0 3 3 3 0 HEAT-like repeat HEAT PF02985.17 CCD22935.1 - 0.073 13.1 0.2 1.9 8.7 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat Atx10homo_assoc PF09759.4 CCD22935.1 - 0.077 12.7 2.1 0.18 11.5 1.2 1.9 1 1 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Vps51 PF08700.6 CCD22936.1 - 4e-10 39.3 1.9 4e-10 39.3 1.3 3.4 4 1 0 4 4 4 1 Vps51/Vps67 COG2 PF06148.6 CCD22936.1 - 8.3e-06 25.7 1.7 8.3e-06 25.7 1.2 3.1 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.4 CCD22936.1 - 0.068 13.1 13.2 0.037 13.9 0.6 3.6 3 1 1 4 4 4 0 Golgi transport complex subunit 5 WD40 PF00400.27 CCD22937.1 - 4.2e-28 96.1 14.1 1.8e-08 33.9 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat LisH PF08513.6 CCD22937.1 - 5.9e-06 25.8 0.2 1.4e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 CCD22937.1 - 7.5e-05 22.5 5.2 0.086 12.5 0.1 4.6 3 2 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CCD22937.1 - 0.0053 16.2 0.0 1.3 8.5 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.1 CCD22937.1 - 0.14 11.0 9.5 0.18 10.7 0.0 2.5 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus zf-C2H2_4 PF13894.1 CCD22938.1 - 0.01 16.0 1.3 0.01 16.0 0.9 2.9 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCD22938.1 - 0.051 13.9 0.9 0.051 13.9 0.6 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Peptidase_C5 PF00770.13 CCD22938.1 - 0.057 12.9 4.4 0.075 12.5 3.1 1.1 1 0 0 1 1 1 0 Adenovirus endoprotease Mito_carr PF00153.22 CCD22939.1 - 5.7e-60 199.0 1.0 2e-20 72.2 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Vac_ImportDeg PF09783.4 CCD22940.1 - 5.4e-53 179.0 4.9 8.9e-53 178.3 3.4 1.4 1 0 0 1 1 1 1 Vacuolar import and degradation protein Pho88 PF10032.4 CCD22941.1 - 1.6e-65 219.9 2.6 1.9e-65 219.7 1.8 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) Fe-S_biosyn PF01521.15 CCD22942.1 - 6.7e-15 54.9 0.1 2.4e-12 46.7 0.1 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3797 PF12677.2 CCD22942.1 - 0.14 11.8 1.0 1.2 8.7 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) SRP1_TIP1 PF00660.12 CCD22943.1 - 6.3e-28 96.6 0.1 3e-27 94.4 0.1 2.3 1 0 0 1 1 1 1 Seripauperin and TIP1 family DUF2615 PF11027.3 CCD22943.1 - 8.6 6.3 14.8 8.6 6.3 0.0 4.5 1 1 3 4 4 4 0 Protein of unknown function (DUF2615) Glyco_trans_1_4 PF13692.1 CCD22945.1 - 1e-14 54.8 0.0 2.4e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CCD22945.1 - 4.9e-12 45.5 0.0 1.4e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CCD22945.1 - 4e-06 26.9 0.0 7.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCD22945.1 - 3.2e-05 24.1 0.0 5.2e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain zf-TFIIIC PF12660.2 CCD22945.1 - 0.076 12.9 0.0 7.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex Spermine_synth PF01564.12 CCD22946.1 - 7.9e-101 336.1 0.1 9.5e-101 335.8 0.1 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 CCD22946.1 - 0.00023 20.7 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 CCD22946.1 - 0.0024 16.8 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 CCD22946.1 - 0.0028 18.0 0.1 0.011 16.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD22946.1 - 0.0053 17.3 0.0 0.0096 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF226 PF02890.9 CCD22946.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 MTS PF05175.9 CCD22946.1 - 0.054 12.8 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 CCD22946.1 - 0.06 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 CCD22946.1 - 0.064 12.4 0.2 0.43 9.7 0.0 2.1 1 1 1 2 2 2 0 O-methyltransferase Oxidored_FMN PF00724.15 CCD22947.1 - 5.3e-22 78.2 0.0 5.9e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NUDIX PF00293.23 CCD22948.1 - 7.3e-17 61.2 0.0 3.5e-16 59.0 0.0 1.8 2 0 0 2 2 2 1 NUDIX domain EnY2 PF10163.4 CCD22949.1 - 1.3e-23 82.7 2.2 1.4e-23 82.5 1.5 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 CHASE3 PF05227.8 CCD22949.1 - 0.002 17.8 0.7 0.0023 17.6 0.5 1.1 1 0 0 1 1 1 1 CHASE3 domain Treslin_N PF15292.1 CCD22949.1 - 0.0079 14.1 0.1 0.0081 14.1 0.1 1.0 1 0 0 1 1 1 1 Treslin N-terminus Pox_E8 PF03394.8 CCD22949.1 - 0.041 13.2 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus E8 protein COMPASS-Shg1 PF05205.7 CCD22949.1 - 0.057 13.7 1.9 0.25 11.6 0.2 2.0 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 Ribosomal_S8 PF00410.14 CCD22949.1 - 0.12 12.1 0.5 0.14 11.9 0.3 1.2 1 0 0 1 1 1 0 Ribosomal protein S8 SNF2_N PF00176.18 CCD22950.1 - 1.8e-73 246.9 0.4 2.7e-73 246.3 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCD22950.1 - 2.6e-10 40.0 0.0 6.8e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 CCD22950.1 - 6.5e-08 32.1 11.3 6.5e-08 32.1 7.9 2.5 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 CCD22950.1 - 2.3e-07 30.4 0.0 4.5e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_2 PF13639.1 CCD22950.1 - 3.3e-05 23.6 8.5 3.3e-05 23.6 5.9 2.2 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCD22950.1 - 0.00021 21.2 9.2 0.00021 21.2 6.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCD22950.1 - 0.00065 19.5 9.5 0.00065 19.5 6.6 2.3 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING YL1 PF05764.8 CCD22950.1 - 0.0032 17.1 16.7 0.006 16.2 11.6 1.4 1 0 0 1 1 1 1 YL1 nuclear protein zf-C3HC4_3 PF13920.1 CCD22950.1 - 0.013 15.1 7.6 0.013 15.1 5.3 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) BUD22 PF09073.5 CCD22950.1 - 0.025 13.6 18.3 0.04 13.0 12.7 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 CCD22950.1 - 0.047 11.6 20.6 0.069 11.0 14.3 1.1 1 0 0 1 1 1 0 Nop14-like family Zn_Tnp_IS91 PF14319.1 CCD22950.1 - 0.49 9.9 10.4 0.34 10.4 1.2 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_5 PF14634.1 CCD22950.1 - 8.7 6.1 22.8 0.081 12.6 6.7 2.4 2 0 0 2 2 2 0 zinc-RING finger domain AMP-binding PF00501.23 CCD22951.1 - 5.3e-71 239.1 0.0 7.1e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CCD22951.1 - 3.3e-69 232.5 0.0 5e-69 231.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 CCD22951.1 - 3.7e-14 52.7 0.0 1e-13 51.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 CCD22951.1 - 6.6e-12 45.3 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCD22951.1 - 2.9e-07 29.4 0.0 7.7e-07 28.0 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 CCD22951.1 - 3.5e-07 31.0 0.0 5.3e-06 27.2 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Condensation PF00668.15 CCD22951.1 - 0.0061 15.4 0.7 0.017 14.0 0.0 1.9 1 1 1 2 2 2 1 Condensation domain Polysacc_synt_2 PF02719.10 CCD22951.1 - 0.052 12.4 0.0 0.14 11.0 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 CCD22951.1 - 0.057 12.3 0.0 0.35 9.7 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Transketolase_N PF00456.16 CCD22952.1 - 1.2e-149 497.7 0.0 2.3e-149 496.7 0.0 1.5 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CCD22952.1 - 1.9e-45 154.5 0.0 3e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCD22952.1 - 2.5e-12 46.8 0.0 6.3e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CCD22952.1 - 2e-06 26.9 0.1 8.8e-05 21.5 0.0 2.4 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 CCD22952.1 - 0.0019 16.9 0.0 0.0093 14.7 0.0 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component XFP_C PF09363.5 CCD22952.1 - 0.21 10.9 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 XFP C-terminal domain DHC_N1 PF08385.7 CCD22952.1 - 0.42 8.9 0.0 0.61 8.3 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 zf-CCHC PF00098.18 CCD22953.1 - 1.6e-06 27.7 2.1 2.6e-06 27.0 1.4 1.4 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 CCD22953.1 - 0.0099 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein eIF3g PF12353.3 CCD22953.1 - 0.029 14.2 0.2 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G CIMR PF00878.13 CCD22955.1 - 2e-09 37.3 1.9 3.3e-05 23.6 0.1 3.1 2 1 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 CCD22955.1 - 4.9e-05 22.8 0.0 9.4e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 Glucosidase II beta subunit-like protein GTP_EFTU PF00009.22 CCD22956.1 - 7.7e-57 191.7 0.0 1.1e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCD22956.1 - 2.3e-35 120.6 0.0 7.1e-35 119.1 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCD22956.1 - 6.4e-17 61.4 2.2 6.4e-17 61.4 1.5 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCD22956.1 - 2.7e-05 23.7 0.6 2.7e-05 23.7 0.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCD22956.1 - 0.0019 18.1 0.2 0.0063 16.4 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase RRM_6 PF14259.1 CCD22957.1 - 6.6e-11 42.0 0.2 2.8e-05 24.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCD22957.1 - 2.6e-10 39.7 3.0 1.4e-06 27.7 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD22957.1 - 1.6e-05 24.6 0.2 0.067 13.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) T_Ag_DNA_bind PF02217.11 CCD22957.1 - 0.076 13.4 0.3 0.27 11.6 0.1 2.0 2 0 0 2 2 2 0 Origin of replication binding protein RP-C_C PF11800.3 CCD22957.1 - 0.099 12.3 2.6 0.16 11.6 1.8 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Thymopoietin PF08198.6 CCD22957.1 - 0.11 12.0 1.7 3 7.4 0.4 3.3 2 1 1 3 3 3 0 Thymopoietin protein RE_Alw26IDE PF09665.5 CCD22958.1 - 0.025 13.3 2.4 0.027 13.1 1.7 1.1 1 0 0 1 1 1 0 Type II restriction endonuclease (RE_Alw26IDE) Poty_PP PF08440.5 CCD22958.1 - 0.034 13.2 1.7 0.044 12.8 1.2 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein DUF445 PF04286.7 CCD22958.1 - 0.054 13.0 2.5 0.063 12.7 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF4422 PF14393.1 CCD22958.1 - 0.061 12.9 2.1 0.077 12.5 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4422) AAA_21 PF13304.1 CCD22958.1 - 0.086 12.7 3.6 0.1 12.5 2.5 1.0 1 0 0 1 1 1 0 AAA domain YkyA PF10368.4 CCD22958.1 - 0.13 11.5 7.4 0.19 11.0 4.7 1.5 1 1 0 1 1 1 0 Putative cell-wall binding lipoprotein tRNA-synt_2b PF00587.20 CCD22959.1 - 1.1e-69 233.5 0.1 1.8e-69 232.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCD22959.1 - 3.6e-22 78.0 0.2 3.6e-22 78.0 0.1 2.4 3 0 0 3 3 3 1 Anticodon binding domain Tau95 PF09734.4 CCD22961.1 - 1.2e-66 225.1 0.6 1.7e-66 224.7 0.4 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit PP2C PF00481.16 CCD22962.1 - 6.7e-60 202.6 0.0 6.9e-57 192.7 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CCD22962.1 - 0.00088 18.7 0.0 0.0072 15.7 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CCD22962.1 - 0.018 14.7 0.0 3.2 7.4 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Glyco_transf_20 PF00982.16 CCD22963.1 - 3.2e-200 665.6 0.1 3.6e-200 665.4 0.1 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 CCD22963.1 - 0.00043 19.8 0.3 0.0021 17.5 0.1 1.9 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 CCD22963.1 - 0.026 13.9 0.8 2.4 7.5 0.1 2.9 2 1 0 2 2 2 0 Glycosyl transferases group 1 ATP-synt_ab PF00006.20 CCD22964.1 - 1.1e-60 204.8 0.0 1.6e-60 204.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCD22964.1 - 2.9e-16 59.9 0.3 5.7e-16 58.9 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCD22964.1 - 6e-14 52.0 1.1 1.4e-13 50.8 0.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CCD22964.1 - 0.00011 21.9 0.7 0.00041 20.1 0.5 2.0 1 0 0 1 1 1 1 HAS barrel domain Atg14 PF10186.4 CCD22965.1 - 3.6e-36 124.6 16.5 4.8e-36 124.2 11.5 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Cep57_MT_bd PF06657.8 CCD22965.1 - 0.12 12.3 8.1 2.1 8.3 2.1 2.8 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Oxidored_FMN PF00724.15 CCD22967.1 - 4.1e-126 420.5 0.0 4.7e-126 420.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1664 PF07889.7 CCD22968.1 - 0.0042 16.8 4.4 0.0042 16.8 3.1 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1664) PH PF00169.24 CCD22969.1 - 1.8e-07 31.3 7.4 7.1e-06 26.1 0.5 2.5 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 CCD22969.1 - 0.0001 22.5 7.8 0.016 15.4 0.6 2.7 2 1 0 2 2 2 2 Pleckstrin homology domain PH_7 PF15408.1 CCD22969.1 - 0.081 12.8 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain TFIIB PF00382.14 CCD22970.1 - 6.4e-41 138.0 9.1 1.1e-27 95.5 0.7 2.6 3 0 0 3 3 3 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CCD22970.1 - 3.5e-13 48.6 0.6 6.2e-13 47.8 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding Ribosomal_60s PF00428.14 CCD22970.1 - 6.3e-05 23.2 7.6 0.0002 21.7 2.2 2.8 3 0 0 3 3 3 1 60s Acidic ribosomal protein SRP54 PF00448.17 CCD22971.1 - 3.5e-79 264.8 0.7 3.5e-79 264.8 0.5 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CCD22971.1 - 3e-24 85.2 14.4 3e-24 85.2 10.0 4.6 4 1 1 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 CCD22971.1 - 4.6e-15 55.4 1.6 4.6e-15 55.4 1.1 2.2 3 0 0 3 3 2 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 CCD22971.1 - 4.2e-06 26.7 0.0 1e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 CCD22971.1 - 4.8e-06 26.1 2.0 1.6e-05 24.4 0.4 2.5 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_31 PF13614.1 CCD22971.1 - 1.9e-05 24.6 0.0 0.042 13.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CCD22971.1 - 5e-05 23.0 0.1 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 CCD22971.1 - 5e-05 22.5 3.3 1.2 8.3 0.0 3.8 3 0 0 3 3 3 2 Signal recognition particle receptor beta subunit CbiA PF01656.18 CCD22971.1 - 8e-05 22.1 0.2 0.00036 19.9 0.1 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 CCD22971.1 - 0.0013 19.5 0.0 0.0025 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain VirE PF05272.6 CCD22971.1 - 0.0062 16.0 0.1 0.024 14.1 0.0 1.9 2 0 0 2 2 2 1 Virulence-associated protein E APS_kinase PF01583.15 CCD22971.1 - 0.0063 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ArgK PF03308.11 CCD22971.1 - 0.0089 14.8 1.4 0.026 13.2 0.0 2.5 3 0 0 3 3 3 1 ArgK protein AAA_22 PF13401.1 CCD22971.1 - 0.011 15.8 0.2 0.047 13.8 0.1 2.3 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.1 CCD22971.1 - 0.012 15.9 0.0 0.057 13.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 CCD22971.1 - 0.013 15.0 0.1 0.048 13.1 0.1 2.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 CCD22971.1 - 0.013 14.5 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 CCD22971.1 - 0.015 14.7 0.4 0.028 13.8 0.2 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 CCD22971.1 - 0.03 14.6 0.8 0.066 13.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CCD22971.1 - 0.032 13.8 0.0 0.072 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 CCD22971.1 - 0.072 13.2 1.2 0.93 9.6 0.7 2.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCD22971.1 - 0.085 12.8 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF1712 PF08217.6 CCD22972.1 - 1.6e-158 528.7 25.9 1.8e-158 528.5 18.0 1.0 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) DUF126 PF01989.11 CCD22972.1 - 0.057 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function DUF126 Ribosomal_S13_N PF08069.7 CCD22972.1 - 0.87 9.4 2.9 0.86 9.4 0.0 2.4 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain AA_permease PF00324.16 CCD22973.1 - 2.9e-122 408.4 32.8 3.3e-122 408.2 22.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD22973.1 - 6.2e-21 74.4 36.7 8.1e-21 74.0 25.4 1.1 1 0 0 1 1 1 1 Amino acid permease ATP-synt_DE_N PF02823.11 CCD22974.1 - 4.5e-18 64.7 0.0 6.1e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain Rad21_Rec8_N PF04825.8 CCD22975.1 - 3.3e-25 88.2 1.3 8.1e-25 86.9 0.1 2.2 2 0 0 2 2 2 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CCD22975.1 - 8.1e-11 40.9 0.0 1.9e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein DRIM PF07539.7 CCD22976.1 - 1.9e-47 160.2 2.7 3.3e-47 159.4 0.2 2.9 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 CCD22976.1 - 0.032 14.3 3.6 41 4.6 0.0 5.9 5 0 0 5 5 5 0 HEAT repeat Arm PF00514.18 CCD22976.1 - 0.093 12.5 1.3 6.8 6.6 0.0 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat EST1 PF10374.4 CCD22977.1 - 0.017 15.1 5.1 0.38 10.7 3.5 2.2 1 1 0 1 1 1 0 Telomerase activating protein Est1 KxDL PF10241.4 CCD22977.1 - 0.51 10.2 2.6 0.51 10.2 0.4 2.0 2 1 1 3 3 3 0 Uncharacterized conserved protein GLE1 PF07817.8 CCD22977.1 - 1.8 7.4 5.9 0.16 10.8 0.6 1.8 2 0 0 2 2 2 0 GLE1-like protein Prefoldin_2 PF01920.15 CCD22978.1 - 1.1e-21 76.5 5.5 1.4e-21 76.2 3.8 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF2935 PF11155.3 CCD22978.1 - 0.037 14.1 0.5 0.042 13.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) DASH_Dad3 PF08656.5 CCD22978.1 - 0.24 11.1 2.2 1.9 8.2 0.2 2.1 2 0 0 2 2 2 0 DASH complex subunit Dad3 bZIP_1 PF00170.16 CCD22978.1 - 0.44 10.5 2.2 7 6.6 0.1 2.2 2 0 0 2 2 2 0 bZIP transcription factor CENP-F_leu_zip PF10473.4 CCD22978.1 - 0.6 9.9 4.9 2 8.2 0.3 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF342 PF03961.8 CCD22978.1 - 0.82 8.0 4.7 2 6.7 3.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DDOST_48kD PF03345.9 CCD22979.1 - 2.9e-115 385.1 9.7 3.6e-115 384.8 6.7 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta GDA1_CD39 PF01150.12 CCD22981.1 - 3.6e-143 477.1 0.2 3.6e-143 477.1 0.2 2.0 2 0 0 2 2 2 1 GDA1/CD39 (nucleoside phosphatase) family GN3L_Grn1 PF08701.6 CCD22982.1 - 6.6e-24 83.6 14.9 1.8e-23 82.2 10.4 1.8 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 CCD22982.1 - 1.1e-21 76.9 1.3 5.1e-15 55.4 0.1 3.2 2 1 1 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCD22982.1 - 6.1e-09 35.3 0.2 1.5e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCD22982.1 - 1e-06 28.6 3.9 0.051 13.3 0.8 3.7 2 2 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 CCD22982.1 - 1.8e-05 24.2 0.1 0.033 13.6 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CCD22982.1 - 3.1e-05 23.1 0.4 6.1e-05 22.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CCD22982.1 - 0.00037 19.6 0.1 0.0016 17.6 0.0 2.1 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 CCD22982.1 - 0.0086 16.5 0.4 0.38 11.2 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 CCD22982.1 - 0.034 14.4 1.8 1.4 9.2 0.0 3.5 4 0 0 4 4 4 0 AAA domain ArgK PF03308.11 CCD22982.1 - 0.042 12.6 0.0 0.087 11.5 0.0 1.4 1 0 0 1 1 1 0 ArgK protein Torsin PF06309.6 CCD22982.1 - 0.14 12.0 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Torsin PUA PF01472.15 CCD22983.1 - 2.5e-21 75.1 0.0 3.9e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.5 CCD22983.1 - 0.0093 15.7 0.7 0.017 14.8 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) Sec3_C PF09763.4 CCD22984.1 - 2.4e-145 485.4 28.6 2.4e-145 485.4 19.8 2.6 3 0 0 3 3 3 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 CCD22984.1 - 6.1e-29 99.7 0.9 6.1e-29 99.7 0.6 2.5 2 0 0 2 2 2 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH NTF2 PF02136.15 CCD22985.1 - 2.6e-35 121.3 0.5 2.9e-35 121.1 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 CCD22985.1 - 0.011 14.8 0.2 0.014 14.4 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Methyltransf_6 PF03737.10 CCD22986.1 - 1.4e-24 86.7 0.0 1.9e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase EF-hand_4 PF12763.2 CCD22987.1 - 2.1e-29 101.3 0.0 2.7e-14 52.7 0.0 3.3 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CCD22987.1 - 9.5e-08 32.0 0.0 0.00085 19.4 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CCD22987.1 - 1.1e-06 27.5 0.0 0.0014 17.7 0.0 3.5 3 0 0 3 3 3 1 EF hand Cwf_Cwc_15 PF04889.7 CCD22987.1 - 1.7e-05 24.6 15.4 1.7e-05 24.6 10.7 4.3 4 0 0 4 4 4 1 Cwf15/Cwc15 cell cycle control protein EF-hand_6 PF13405.1 CCD22987.1 - 3.6e-05 23.2 0.0 0.19 11.7 0.0 3.9 4 0 0 4 4 4 1 EF-hand domain DUF1720 PF08226.6 CCD22987.1 - 0.00046 20.2 63.3 0.0012 18.8 13.9 8.4 2 2 4 6 6 6 4 Domain of unknown function (DUF1720) PA26 PF04636.8 CCD22987.1 - 9.1 4.8 13.7 0.54 8.8 3.5 2.6 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) SRP1_TIP1 PF00660.12 CCD22988.1 - 3.9e-36 123.0 0.1 3.9e-36 123.0 0.1 1.9 2 1 1 3 3 3 1 Seripauperin and TIP1 family SLD3 PF08639.5 CCD22988.1 - 0.013 14.1 11.0 0.018 13.6 7.6 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 FAM196 PF15265.1 CCD22988.1 - 0.37 9.9 13.7 0.46 9.6 9.5 1.1 1 0 0 1 1 1 0 FAM196 family AKAP2_C PF15304.1 CCD22988.1 - 0.51 9.9 12.5 0.67 9.5 8.7 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Herpes_BLLF1 PF05109.8 CCD22988.1 - 0.66 7.8 25.4 0.77 7.6 17.6 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TFIIA PF03153.8 CCD22988.1 - 0.78 9.5 12.6 1.2 8.9 8.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Macoilin PF09726.4 CCD22988.1 - 1 7.5 23.7 1.2 7.3 16.4 1.1 1 0 0 1 1 1 0 Transmembrane protein DDHD PF02862.12 CCD22988.1 - 2.3 7.9 11.4 3.4 7.3 7.9 1.3 1 0 0 1 1 1 0 DDHD domain SOBP PF15279.1 CCD22988.1 - 3.7 7.8 10.1 5.2 7.3 7.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein ABC2_membrane PF01061.19 CCD22990.1 - 4.8e-67 225.1 66.0 2e-35 121.8 11.1 3.3 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 CCD22990.1 - 1.1e-28 98.9 3.7 2.7e-26 91.2 0.1 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_tran PF00005.22 CCD22990.1 - 2.1e-28 99.3 0.0 9.2e-16 58.3 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CCD22990.1 - 1.4e-09 37.5 57.8 8e-06 25.1 17.0 3.9 2 2 2 4 4 4 2 ABC-2 family transporter protein DUF258 PF03193.11 CCD22990.1 - 1e-05 24.7 0.1 1.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 CCD22990.1 - 0.00018 21.5 1.3 0.00018 21.5 0.9 5.6 5 2 1 6 6 6 1 AAA domain SMC_N PF02463.14 CCD22990.1 - 0.00028 20.1 0.5 0.016 14.4 0.3 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CCD22990.1 - 0.0047 17.0 0.0 0.014 15.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCD22990.1 - 0.006 16.5 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 CCD22990.1 - 0.018 15.3 1.4 0.035 14.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 CCD22990.1 - 0.019 14.4 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CCD22990.1 - 0.02 15.2 0.2 0.073 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCD22990.1 - 0.053 13.0 0.4 0.13 11.8 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CCD22990.1 - 0.082 12.2 0.0 0.23 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CCD22990.1 - 0.09 12.5 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain TOM13 PF08219.6 CCD22991.1 - 1.5e-27 95.1 1.5 3.1e-27 94.1 1.1 1.6 1 1 0 1 1 1 1 Outer membrane protein TOM13 DUF3508 PF12018.3 CCD22991.1 - 0.005 15.8 0.0 0.0055 15.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3508) LETM1 PF07766.8 CCD22992.1 - 6.9e-101 336.7 6.7 1.2e-100 336.0 4.7 1.4 1 0 0 1 1 1 1 LETM1-like protein bZIP_1 PF00170.16 CCD22993.1 - 0.0054 16.6 10.8 0.0054 16.6 7.5 2.7 2 1 1 3 3 3 1 bZIP transcription factor Ribosomal_L20 PF00453.13 CCD22993.1 - 0.036 13.9 2.0 0.088 12.7 1.4 1.6 1 0 0 1 1 1 0 Ribosomal protein L20 bZIP_Maf PF03131.12 CCD22993.1 - 2.1 8.7 12.7 0.12 12.6 4.4 2.1 2 1 1 3 3 3 0 bZIP Maf transcription factor bZIP_2 PF07716.10 CCD22993.1 - 8.1 6.3 19.7 0.048 13.4 6.9 2.4 3 0 0 3 3 3 0 Basic region leucine zipper Glyco_hydro_72 PF03198.9 CCD22994.1 - 1.9e-144 480.4 9.7 2.5e-144 480.0 6.7 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 CCD22994.1 - 2.5e-05 23.6 0.3 0.00023 20.4 0.2 2.3 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Nop14 PF04147.7 CCD22994.1 - 0.0026 15.7 5.2 0.0034 15.3 3.6 1.1 1 0 0 1 1 1 1 Nop14-like family Apt1 PF10351.4 CCD22994.1 - 0.21 10.4 8.9 0.37 9.5 6.2 1.4 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF572 PF04502.8 CCD22994.1 - 1 8.5 8.7 1.5 7.9 6.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) PBP1_TM PF14812.1 CCD22994.1 - 1.1 9.6 6.3 2.1 8.6 4.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NOA36 PF06524.7 CCD22994.1 - 1.2 8.3 6.0 2.1 7.5 4.2 1.4 1 0 0 1 1 1 0 NOA36 protein Pet127 PF08634.5 CCD22995.1 - 5.7e-109 363.4 18.3 5.9e-109 363.4 8.1 3.0 2 1 0 2 2 2 1 Mitochondrial protein Pet127 EMP24_GP25L PF01105.19 CCD22996.1 - 6.5e-35 120.4 0.0 7.6e-35 120.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Ribosomal_S30AE PF02482.14 CCD22996.1 - 0.015 15.7 0.0 0.028 14.8 0.0 1.4 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein Kisspeptin PF15152.1 CCD22996.1 - 0.083 13.5 0.0 0.17 12.5 0.0 1.5 1 0 0 1 1 1 0 Kisspeptin B56 PF01603.15 CCD22997.1 - 2.9e-147 490.5 25.0 2.5e-139 464.4 10.3 2.2 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) SMC_N PF02463.14 CCD22998.1 - 2.1e-14 53.2 33.8 7.4e-14 51.5 23.4 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCD22998.1 - 1e-07 32.4 51.3 1e-07 32.4 35.5 5.2 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 CCD22998.1 - 5.6e-05 22.5 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CCD22998.1 - 0.017 14.5 0.0 0.05 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain HrpB7 PF09486.5 CCD22998.1 - 0.018 14.9 0.5 0.018 14.9 0.4 3.4 4 0 0 4 4 4 0 Bacterial type III secretion protein (HrpB7) ABC_tran PF00005.22 CCD22998.1 - 0.022 15.0 0.0 0.022 15.0 0.0 5.2 3 2 0 4 4 4 0 ABC transporter FUSC PF04632.7 CCD22998.1 - 0.094 11.1 0.9 0.18 10.2 0.7 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family tRNA-synt_1c PF00749.16 CCD22999.1 - 1.9e-109 365.1 0.0 2.8e-109 364.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain UxuA PF03786.8 CCD22999.1 - 0.0068 15.0 0.4 0.012 14.2 0.0 1.5 2 0 0 2 2 2 1 D-mannonate dehydratase (UxuA) Put_DNA-bind_N PF06971.8 CCD22999.1 - 0.056 13.2 0.6 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Putative DNA-binding protein N-terminus ADH_N PF08240.7 CCD23000.1 - 8.1e-27 93.1 2.7 1.5e-26 92.2 1.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCD23000.1 - 1.8e-17 63.1 0.1 3e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCD23000.1 - 2e-05 23.8 0.2 4.2e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CCD23000.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 CCD23000.1 - 0.081 12.7 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF775 PF05603.7 CCD23001.1 - 4.4e-55 186.3 0.1 6e-55 185.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF775) WBS_methylT PF12589.3 CCD23002.1 - 0.22 12.0 6.2 0.064 13.7 1.8 2.0 2 0 0 2 2 2 0 Methyltransferase involved in Williams-Beuren syndrome Ribosomal_60s PF00428.14 CCD23003.1 - 3.8e-26 91.2 9.2 4.5e-26 91.0 6.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein RRM_1 PF00076.17 CCD23004.1 - 3e-19 68.3 3.2 6.6e-15 54.5 0.1 4.5 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD23004.1 - 1.5e-14 53.6 1.7 2.8e-11 43.2 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD23004.1 - 4.7e-09 35.9 1.3 4.3e-05 23.2 0.1 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 CCD23004.1 - 0.0012 18.2 0.0 0.0061 15.9 0.0 2.2 1 0 0 1 1 1 1 Sporulation protein family 7 Nup35_RRM PF05172.8 CCD23004.1 - 0.027 14.2 0.1 0.083 12.6 0.1 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Exo_endo_phos PF03372.18 CCD23006.1 - 1.8e-16 60.8 0.0 2.2e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PolyA_pol_RNAbd PF12627.2 CCD23007.1 - 0.27 10.8 3.0 1.1 8.8 0.2 2.7 3 0 0 3 3 3 0 Probable RNA and SrmB- binding site of polymerase A Mannosyl_trans3 PF11051.3 CCD23008.1 - 6.9e-64 215.8 1.4 9.4e-64 215.3 1.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Pkinase PF00069.20 CCD23009.1 - 1.9e-61 207.5 0.7 1.2e-60 204.8 0.1 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23009.1 - 7.1e-20 71.1 0.0 1.3e-19 70.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD23009.1 - 2.3e-08 33.3 0.0 5.1e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCD23009.1 - 0.00035 19.7 0.0 0.00077 18.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.19 CCD23009.1 - 0.012 15.3 0.0 0.2 11.4 0.0 2.5 2 0 0 2 2 2 0 PAS fold LAMTOR PF15454.1 CCD23010.1 - 0.11 12.8 0.9 0.2 11.9 0.6 1.4 1 0 0 1 1 1 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator GSH_synth_ATP PF03917.12 CCD23011.1 - 8.9e-107 356.8 0.0 1.1e-106 356.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CCD23011.1 - 5.5e-34 116.4 0.2 1e-33 115.5 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase PMT PF02366.13 CCD23013.1 - 2.7e-82 275.8 18.9 2.7e-82 275.8 13.1 2.4 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCD23013.1 - 1.6e-26 93.0 1.3 2.8e-26 92.2 0.9 1.4 1 0 0 1 1 1 1 MIR domain LDB19 PF13002.2 CCD23014.1 - 1.2e-92 308.7 1.0 2.1e-92 307.8 0.7 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 CCD23014.1 - 0.00012 21.9 1.4 0.00048 19.9 0.2 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Ribosomal_L28e PF01778.12 CCD23015.1 - 1.3e-33 115.8 0.6 1.3e-33 115.8 0.4 2.2 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.9 CCD23015.1 - 1.3e-32 111.8 17.5 1.3e-32 111.8 12.1 2.8 2 1 0 2 2 2 1 Mak16 protein C-terminal region TFIIF_alpha PF05793.7 CCD23015.1 - 0.11 10.8 33.6 0.13 10.6 23.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CENP-T PF15511.1 CCD23015.1 - 0.14 11.3 16.1 0.18 10.9 11.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2462 PF09495.5 CCD23015.1 - 2.9 8.6 9.0 0.73 10.6 0.6 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2462) Aldedh PF00171.17 CCD23016.1 - 6.4e-16 57.7 0.1 3.8e-13 48.5 0.0 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family FliJ PF02050.11 CCD23017.1 - 0.47 10.5 14.3 0.12 12.3 2.4 2.8 3 0 0 3 3 3 0 Flagellar FliJ protein Myosin_head PF00063.16 CCD23018.1 - 1.5e-262 872.6 16.1 1.5e-262 872.6 11.1 2.1 2 1 1 3 3 3 1 Myosin head (motor domain) DIL PF01843.14 CCD23018.1 - 2.5e-34 117.3 0.7 1.3e-33 114.9 0.5 2.4 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 CCD23018.1 - 1.2e-08 33.8 18.4 0.012 15.1 0.4 6.0 5 0 0 5 5 5 5 IQ calmodulin-binding motif AAA_22 PF13401.1 CCD23018.1 - 0.0045 17.1 0.0 0.0045 17.1 0.0 3.3 3 1 1 4 4 4 1 AAA domain Myosin_N PF02736.14 CCD23018.1 - 0.051 13.2 0.1 0.14 11.8 0.1 1.8 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 CCD23018.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 CCD23018.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.1 2 1 0 2 2 2 0 ABC transporter Synaptobrevin PF00957.16 CCD23019.1 - 8e-32 108.7 1.7 9.1e-32 108.5 1.2 1.0 1 0 0 1 1 1 1 Synaptobrevin ODV-E18 PF10717.4 CCD23019.1 - 0.06 12.8 0.2 0.1 12.0 0.2 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 PRT_C PF08372.5 CCD23019.1 - 0.093 12.2 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal Phage_rep_O PF04492.8 CCD23019.1 - 0.11 12.7 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication protein O DUF912 PF06024.7 CCD23019.1 - 0.32 11.0 1.5 0.43 10.6 1.0 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 CCD23019.1 - 7.8 6.0 6.1 11 5.6 4.3 1.2 1 1 0 1 1 1 0 Rifin/stevor family bZIP_1 PF00170.16 CCD23021.1 - 2.1e-14 53.1 10.2 2.1e-14 53.1 7.1 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CCD23021.1 - 2.6e-11 43.1 10.8 2.6e-11 43.1 7.5 2.2 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 CCD23021.1 - 0.0019 18.4 7.4 0.0019 18.4 5.1 2.3 3 0 0 3 3 3 1 bZIP Maf transcription factor DivIC PF04977.10 CCD23021.1 - 0.16 11.4 4.9 0.49 9.9 3.0 2.2 1 1 0 1 1 1 0 Septum formation initiator TSC22 PF01166.13 CCD23021.1 - 0.87 9.6 5.7 0.38 10.7 1.5 2.2 2 0 0 2 2 2 0 TSC-22/dip/bun family Urm1 PF09138.6 CCD23022.1 - 4.4e-36 122.8 0.5 4.9e-36 122.7 0.3 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CCD23022.1 - 0.0003 21.1 0.1 0.00039 20.8 0.1 1.2 1 0 0 1 1 1 1 ThiS family COPIIcoated_ERV PF07970.7 CCD23024.1 - 6.6e-72 241.7 0.4 8.1e-72 241.4 0.3 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCD23024.1 - 1.7e-31 108.0 0.2 3.6e-31 106.9 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PX PF00787.19 CCD23025.1 - 2.8e-21 75.4 0.1 5.6e-21 74.4 0.1 1.5 1 0 0 1 1 1 1 PX domain CBFD_NFYB_HMF PF00808.18 CCD23026.1 - 4.5e-19 68.2 1.0 8.5e-19 67.3 0.7 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCD23026.1 - 2.4e-16 59.5 0.3 3.4e-16 59.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAFII28 PF04719.9 CCD23026.1 - 0.02 14.6 0.1 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region SAM_2 PF07647.12 CCD23027.1 - 3.5e-07 29.9 0.1 8.3e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCD23027.1 - 0.00013 22.1 0.1 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Innate_immun PF12782.2 CCD23027.1 - 0.69 9.0 8.7 1.4 8.1 6.1 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family PDEase_I PF00233.14 CCD23028.1 - 1.4e-47 162.4 8.2 9.3e-46 156.4 4.8 2.5 1 1 1 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Methyltransf_28 PF02636.12 CCD23028.1 - 0.0019 17.6 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase HD PF01966.17 CCD23028.1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 HD domain eIF2A PF08662.6 CCD23029.1 - 7e-26 91.1 2.3 3.6e-23 82.2 0.4 3.6 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 CCD23029.1 - 3.6e-09 36.1 0.1 8.7e-09 34.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD23029.1 - 3.2e-06 27.0 0.1 7.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD23029.1 - 5.6e-05 22.8 0.0 0.00015 21.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ELYS PF13934.1 CCD23029.1 - 0.048 13.3 0.4 0.37 10.4 0.1 2.0 2 0 0 2 2 2 0 Nuclear pore complex assembly WD40 PF00400.27 CCD23029.1 - 0.71 9.8 4.1 84 3.2 0.0 4.6 6 0 0 6 6 6 0 WD domain, G-beta repeat Proteasome PF00227.21 CCD23030.1 - 1.2e-50 171.5 0.0 1.9e-50 170.7 0.0 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 CCD23030.1 - 1.1e-11 43.8 0.9 1.5e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DLH PF01738.13 CCD23031.1 - 3.1e-31 108.3 0.0 3.5e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCD23031.1 - 1.1e-07 31.6 0.0 1.5e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCD23031.1 - 0.0023 17.8 0.0 0.22 11.3 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family DUF2766 PF10964.3 CCD23031.1 - 0.0095 15.8 0.0 3.1 7.7 0.0 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2766) Zn_clus PF00172.13 CCD23032.1 - 7.8e-11 41.7 9.7 1.4e-10 40.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CH PF00307.26 CCD23033.1 - 3.7e-10 39.7 0.0 5.1e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain Peroxin-22 PF12827.2 CCD23034.1 - 1.1e-22 79.8 3.9 1.1e-22 79.8 2.7 1.6 1 1 1 2 2 2 1 Peroxisomal biogenesis protein family Phage_holin PF04688.8 CCD23034.1 - 0.0041 16.6 0.3 0.011 15.2 0.2 1.8 1 0 0 1 1 1 1 Phage lysis protein, holin Rad1 PF02144.11 CCD23035.1 - 2.5e-66 223.2 0.5 3.5e-66 222.7 0.3 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ribosomal_L7Ae PF01248.21 CCD23036.1 - 9.7e-24 82.7 0.2 1.3e-23 82.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.7 CCD23036.1 - 0.0078 16.2 2.3 0.045 13.7 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1269) DUF2622 PF11080.3 CCD23036.1 - 0.16 11.8 1.3 0.91 9.4 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2622) SapB_1 PF05184.10 CCD23036.1 - 2.7 7.9 7.3 6.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 GDI PF00996.13 CCD23037.1 - 9.6e-57 192.2 0.1 1.3e-56 191.8 0.1 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor FAD_binding_3 PF01494.14 CCD23037.1 - 0.021 13.9 0.1 0.039 12.9 0.0 1.4 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 CCD23037.1 - 0.025 13.9 0.1 1.9 7.8 0.1 2.4 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.1 CCD23037.1 - 0.035 14.1 0.0 0.094 12.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Kelch_3 PF13415.1 CCD23038.1 - 4.7e-12 45.7 2.5 0.00092 19.3 0.0 5.9 6 1 0 6 6 6 2 Galactose oxidase, central domain Kelch_4 PF13418.1 CCD23038.1 - 1.8e-09 37.1 11.1 4.2e-05 23.2 0.3 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CCD23038.1 - 1.9e-07 30.9 9.2 0.00022 21.2 0.2 5.6 6 1 0 6 6 6 2 Kelch motif Kelch_5 PF13854.1 CCD23038.1 - 5.9e-06 26.1 10.5 1.4 9.0 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CCD23038.1 - 0.0046 16.6 9.3 0.43 10.4 1.1 4.6 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 CCD23038.1 - 0.046 13.2 10.3 1.3 8.5 0.4 4.5 5 0 0 5 5 5 0 Kelch motif CTP-dep_RFKase PF01982.11 CCD23039.1 - 0.44 10.1 4.3 0.49 10.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF120 LRR_4 PF12799.2 CCD23040.1 - 3.4e-13 48.8 73.9 4.3e-07 29.4 0.7 8.5 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCD23040.1 - 0.00031 20.4 29.3 0.0006 19.5 10.2 6.4 4 3 3 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 CCD23040.1 - 0.013 15.4 1.4 0.013 15.4 1.0 10.0 8 2 1 10 10 10 0 Leucine Rich repeat LRR_9 PF14580.1 CCD23040.1 - 0.22 11.0 17.7 1.7 8.1 0.3 4.3 2 1 2 4 4 4 0 Leucine-rich repeat LRR_7 PF13504.1 CCD23040.1 - 2.9 8.4 45.5 31 5.3 0.5 12.3 12 1 1 13 13 13 0 Leucine rich repeat LRR_1 PF00560.28 CCD23040.1 - 4.6 7.6 62.1 0.92 9.7 0.3 12.0 9 2 2 11 11 11 0 Leucine Rich Repeat Aldedh PF00171.17 CCD23041.1 - 2.4e-178 593.2 0.2 2.8e-178 592.9 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCD23041.1 - 0.014 14.0 0.0 0.026 13.2 0.0 1.5 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Glyco_transf_15 PF01793.11 CCD23042.1 - 5.4e-144 479.1 17.4 6.7e-144 478.8 12.0 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SRP1_TIP1 PF00660.12 CCD23043.1 - 4.8e-27 93.8 0.9 4.8e-27 93.8 0.6 2.1 2 0 0 2 2 2 1 Seripauperin and TIP1 family Toxin_6 PF05453.7 CCD23043.1 - 3.5 7.9 14.1 14 5.9 0.2 3.5 4 0 0 4 4 4 0 BmTXKS1/BmP02 toxin family Pmp3 PF01679.12 CCD23044.1 - 1.3e-17 63.1 5.5 1.7e-17 62.7 3.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator YlaC PF10777.4 CCD23044.1 - 0.012 15.2 0.2 0.018 14.5 0.1 1.3 1 0 0 1 1 1 0 Inner membrane protein YlaC NAD_binding_5 PF07994.7 CCD23046.1 - 1e-111 373.1 0.1 1.5e-111 372.6 0.1 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CCD23046.1 - 3.6e-43 145.9 2.7 1.3e-42 144.1 1.9 2.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Vps35 PF03635.12 CCD23047.1 - 3.3e-145 485.2 41.1 4.1e-145 484.9 28.5 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 6PF2K PF01591.13 CCD23048.1 - 8e-81 270.3 2.6 1.4e-80 269.5 1.8 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCD23048.1 - 3.2e-32 111.8 0.2 8.9e-32 110.3 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CCD23048.1 - 9.8e-07 28.7 0.0 2.1e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCD23048.1 - 4.8e-06 26.9 0.8 0.003 17.8 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 CCD23048.1 - 2.2e-05 25.2 0.0 0.00022 22.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 CCD23048.1 - 0.0055 15.9 0.3 0.009 15.2 0.2 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CCD23048.1 - 0.016 14.3 0.0 0.035 13.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF3922 PF13059.1 CCD23048.1 - 0.024 14.7 2.2 7.8 6.7 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3992) His_Phos_2 PF00328.17 CCD23048.1 - 0.027 13.8 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) Peptidase_S64 PF08192.6 CCD23049.1 - 1e-229 764.4 27.1 1.6e-227 757.2 18.8 2.4 1 1 0 1 1 1 1 Peptidase family S64 zf-RING_2 PF13639.1 CCD23050.1 - 0.0031 17.3 5.4 0.0091 15.8 3.8 1.8 1 1 0 1 1 1 1 Ring finger domain DUF4174 PF13778.1 CCD23050.1 - 0.051 13.6 0.0 0.24 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4174) zf-C3HC4 PF00097.20 CCD23050.1 - 0.2 11.3 6.0 0.61 9.7 4.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCD23050.1 - 1.4 8.6 5.2 3.4 7.4 3.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_1 PF14446.1 CCD23050.1 - 4.2 7.1 6.9 20 5.0 0.3 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 PIR PF00399.14 CCD23051.1 - 4.4e-05 22.6 4.1 4.4e-05 22.6 2.9 2.7 2 0 0 2 2 2 1 Yeast PIR protein repeat RAP1 PF07218.6 CCD23051.1 - 0.61 8.1 7.9 0.75 7.8 5.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.4 CCD23051.1 - 2.4 6.3 5.4 2.8 6.1 3.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Sporozoite_P67 PF05642.6 CCD23051.1 - 3.4 5.4 13.8 4 5.1 9.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PIR PF00399.14 CCD23052.1 - 5.3e-49 161.9 96.5 2.3e-08 33.0 1.4 7.9 7 0 0 7 7 7 7 Yeast PIR protein repeat TFIIA PF03153.8 CCD23052.1 - 1.1 9.0 19.2 1.4 8.6 13.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2072 PF09845.4 CCD23052.1 - 1.3 8.9 3.6 7.7 6.4 2.5 2.2 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) DUF3536 PF12055.3 CCD23052.1 - 6.2 5.8 7.9 8.2 5.5 4.9 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3536) PIR PF00399.14 CCD23053.1 - 2.4e-96 312.1 157.4 1.9e-08 33.3 4.4 12.8 12 0 0 12 12 12 12 Yeast PIR protein repeat HCV_NS5a_1a PF08300.8 CCD23053.1 - 0.00023 20.9 5.0 14 5.6 0.0 5.5 1 1 4 6 6 6 4 Hepatitis C virus non-structural 5a zinc finger domain DnaJ PF00226.26 CCD23054.1 - 6e-18 64.3 0.6 1.5e-17 63.0 0.4 1.7 1 0 0 1 1 1 1 DnaJ domain DUF2277 PF10041.4 CCD23054.1 - 0.026 14.4 0.0 0.067 13.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2277) Pkinase PF00069.20 CCD23055.1 - 1.1e-69 234.5 0.0 1.5e-69 234.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23055.1 - 1.1e-39 136.1 0.0 1.6e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD23055.1 - 7.1e-05 21.8 0.0 0.00014 20.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 CCD23055.1 - 0.039 13.3 0.4 0.46 9.7 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.18 CCD23055.1 - 0.057 13.1 1.0 0.088 12.5 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pex14_N PF04695.8 CCD23055.1 - 0.23 11.5 3.4 0.37 10.8 2.3 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 CCD23056.1 - 3.1e-50 170.7 0.0 6.3e-50 169.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23056.1 - 3.1e-18 65.7 0.0 6.5e-18 64.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCD23056.1 - 0.014 14.4 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCD23056.1 - 0.027 13.4 0.0 0.063 12.2 0.0 1.6 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CCD23056.1 - 0.13 12.0 0.3 0.26 10.9 0.2 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family CAP PF00188.21 CCD23057.1 - 1.3e-18 67.6 1.0 1.3e-18 67.6 0.7 3.0 3 1 0 3 3 3 1 Cysteine-rich secretory protein family UcrQ PF02939.11 CCD23058.1 - 2.5e-37 126.5 2.1 2.8e-37 126.3 1.4 1.0 1 0 0 1 1 1 1 UcrQ family Ebp2 PF05890.7 CCD23059.1 - 4.8e-88 294.9 33.7 4.8e-88 294.9 23.3 3.1 1 1 2 3 3 3 1 Eukaryotic rRNA processing protein EBP2 SRI PF08236.6 CCD23060.1 - 1.7e-23 82.3 5.6 1.7e-23 82.3 3.9 2.3 1 1 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 CCD23060.1 - 1.2e-21 77.6 0.2 1.2e-21 77.6 0.2 4.1 3 2 0 3 3 3 1 SET domain DUF2839 PF10999.3 CCD23061.1 - 0.00021 21.2 2.0 0.029 14.3 0.7 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2839) Rifin_STEVOR PF02009.11 CCD23061.1 - 0.00041 20.1 0.8 0.00064 19.4 0.6 1.2 1 0 0 1 1 1 1 Rifin/stevor family Claudin_2 PF13903.1 CCD23061.1 - 0.0092 15.6 0.0 0.02 14.5 0.0 1.6 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Wzy_C PF04932.10 CCD23061.1 - 0.032 14.0 0.0 0.064 13.0 0.0 1.5 1 1 0 1 1 1 0 O-Antigen ligase Condensation PF00668.15 CCD23061.1 - 0.066 12.0 0.7 3.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Condensation domain DUF2177 PF09945.4 CCD23061.1 - 0.12 12.3 0.4 0.37 10.7 0.0 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) ODV-E18 PF10717.4 CCD23061.1 - 0.13 11.7 0.1 0.13 11.7 0.1 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF3753 PF12575.3 CCD23061.1 - 0.14 11.9 4.4 0.23 11.2 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) EphA2_TM PF14575.1 CCD23061.1 - 4.7 7.6 5.6 1.6 9.1 0.8 2.4 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_M20 PF01546.23 CCD23062.1 - 1.3e-22 80.2 0.0 2.3e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCD23062.1 - 7.7e-13 48.1 0.0 1.5e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Rep_fac-A_3 PF08661.6 CCD23063.1 - 2.4e-29 101.4 0.0 2.7e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 KRE9 PF05390.6 CCD23064.1 - 8.6e-47 157.9 7.6 2.8e-46 156.2 5.3 1.9 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CCD23064.1 - 1.2e-13 51.3 2.6 1.2e-13 51.3 1.8 2.7 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CDO_I PF05995.7 CCD23064.1 - 0.017 14.2 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Cysteine dioxygenase type I SWIRM PF04433.12 CCD23065.1 - 1.4e-31 108.4 0.2 4.1e-31 106.9 0.1 1.9 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 CCD23065.1 - 3.6e-08 33.3 0.0 9.1e-08 32.0 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCD23065.1 - 6.9e-07 29.2 0.1 2.1e-06 27.7 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain FLO_LFY PF01698.11 CCD23065.1 - 0.0024 16.7 3.3 0.0024 16.7 2.3 4.1 3 1 0 4 4 4 1 Floricaula / Leafy protein Ribosomal_L22 PF00237.14 CCD23066.1 - 4.6e-33 113.3 0.2 4.6e-33 113.3 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e Fis1_TPR_C PF14853.1 CCD23066.1 - 0.033 14.0 0.1 11 6.0 0.0 2.7 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat CRT10 PF08728.5 CCD23066.1 - 0.063 11.2 0.2 0.065 11.2 0.2 1.1 1 0 0 1 1 1 0 CRT10 ATG27 PF09451.5 CCD23067.1 - 3e-64 216.8 1.9 5e-64 216.1 1.3 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 PBP1_TM PF14812.1 CCD23067.1 - 8.1e-05 22.8 1.3 0.00015 22.0 0.9 1.4 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 CCD23067.1 - 0.0012 18.9 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0233 PF06781.7 CCD23067.1 - 0.071 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) DUF2956 PF11169.3 CCD23067.1 - 0.077 12.9 0.1 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) DUF2370 PF10176.4 CCD23067.1 - 0.12 11.6 0.1 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Prefoldin_2 PF01920.15 CCD23068.1 - 1.8e-11 43.7 12.7 2.3e-11 43.3 8.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF4568 PF15132.1 CCD23068.1 - 0.016 14.4 1.3 0.019 14.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) DUF948 PF06103.6 CCD23068.1 - 1 9.2 9.5 2.4 8.0 1.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ORF6C PF10552.4 CCD23068.1 - 1.5 8.6 9.6 0.47 10.1 0.3 2.1 1 1 1 2 2 2 0 ORF6C domain SlyX PF04102.7 CCD23068.1 - 5.6 7.4 10.7 11 6.4 0.4 2.8 2 1 1 3 3 3 0 SlyX Med28 PF11594.3 CCD23068.1 - 6.9 6.9 9.5 7.9 6.7 5.6 1.8 1 1 1 2 2 2 0 Mediator complex subunit 28 ATP12 PF07542.6 CCD23069.1 - 5.2e-27 94.2 0.0 1.1e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 ATP12 chaperone protein Glyco_transf_34 PF05637.7 CCD23070.1 - 3.8e-58 196.8 0.1 5.2e-58 196.3 0.1 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Gon7 PF08738.5 CCD23071.1 - 1.3e-33 115.0 0.2 1.6e-33 114.7 0.1 1.1 1 0 0 1 1 1 1 Gon7 family DUF2758 PF10957.3 CCD23071.1 - 0.077 12.8 2.3 1 9.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2758) L_lactis_RepB_C PF06430.7 CCD23071.1 - 0.085 12.9 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Lactococcus lactis RepB C-terminus Myb_CC_LHEQLE PF14379.1 CCD23071.1 - 0.14 11.7 1.1 0.21 11.2 0.8 1.3 1 0 0 1 1 1 0 MYB-CC type transfactor, LHEQLE motif muHD PF10291.4 CCD23073.1 - 4.1e-65 219.5 2.1 6e-65 218.9 0.1 2.3 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain Pkinase PF00069.20 CCD23074.1 - 2.1e-46 158.2 0.5 5.1e-46 156.9 0.4 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23074.1 - 1.5e-27 96.3 0.1 3.2e-27 95.2 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD23074.1 - 0.0026 16.7 0.0 0.0099 14.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCD23074.1 - 0.29 10.8 0.0 0.61 9.7 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L39 PF00832.15 CCD23075.1 - 3.6e-22 77.5 12.1 4.3e-22 77.2 8.4 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Ribosomal_S8 PF00410.14 CCD23076.1 - 7.4e-27 93.7 0.1 1e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S11 PF00411.14 CCD23077.1 - 2.4e-40 137.1 1.0 2.9e-40 136.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 UQ_con PF00179.21 CCD23078.1 - 0.035 13.5 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme TPT PF03151.11 CCD23079.1 - 6.4e-39 133.0 1.7 6.4e-39 133.0 1.2 3.2 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 CCD23079.1 - 0.0001 21.3 3.5 0.0001 21.3 2.4 2.4 2 1 0 2 2 2 1 UAA transporter family EamA PF00892.15 CCD23079.1 - 0.15 12.1 36.8 0.024 14.6 9.0 3.9 3 2 1 4 4 4 0 EamA-like transporter family AAA_22 PF13401.1 CCD23080.1 - 2.8e-09 37.1 0.0 7.9e-09 35.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CCD23080.1 - 2.8e-08 34.0 0.0 1.3e-07 31.8 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCD23080.1 - 1.2e-06 28.6 0.0 9e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 CCD23080.1 - 0.0015 18.2 0.0 0.0038 16.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Cdc6_C PF09079.6 CCD23080.1 - 0.0048 16.5 0.1 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 CDC6, C terminal AAA_5 PF07728.9 CCD23080.1 - 0.012 15.3 0.3 8.9 6.0 0.0 3.9 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 CCD23080.1 - 0.032 13.9 0.0 0.19 11.4 0.0 2.1 1 1 0 1 1 1 0 Archaeal ATPase DNA_Packaging PF11053.3 CCD23080.1 - 0.041 13.4 0.5 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Terminase DNA packaging enzyme NYD-SP28_assoc PF14775.1 CCD23080.1 - 0.077 12.7 0.1 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Sperm tail C-terminal domain IstB_IS21 PF01695.12 CCD23080.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Myb_DNA-binding PF00249.26 CCD23081.1 - 1.7e-06 28.0 0.0 6.7e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Ribosomal_S15 PF00312.17 CCD23081.1 - 0.018 14.7 2.0 2.1 8.1 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein S15 UCH PF00443.24 CCD23082.1 - 1.9e-86 289.5 1.4 1.9e-86 289.5 0.9 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCD23082.1 - 6e-25 88.2 7.4 8.1e-17 61.5 1.5 2.8 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CCD23082.1 - 3.2e-07 30.6 0.2 3.2e-07 30.6 0.1 3.3 2 1 0 2 2 2 1 DUSP domain TF_Zn_Ribbon PF08271.7 CCD23082.1 - 4.6 6.6 6.8 0.59 9.5 0.3 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding SPX PF03105.14 CCD23083.1 - 7.9e-43 147.2 29.6 2.1e-41 142.5 20.6 2.2 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CCD23083.1 - 9.6e-21 74.1 33.8 1.4e-20 73.6 23.4 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CCD23083.1 - 9e-14 50.8 36.4 1.3e-13 50.2 22.9 2.0 1 1 1 2 2 2 2 Citrate transporter VirB3 PF05101.8 CCD23083.1 - 6.1 6.8 10.1 3 7.8 0.2 3.6 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein DEAD PF00270.24 CCD23086.1 - 1.4e-10 40.8 0.0 1.4e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD PF00270.24 CCD23087.1 - 3.4e-10 39.6 0.0 2.8e-09 36.7 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Cys_Met_Meta_PP PF01053.15 CCD23093.1 - 4.6e-51 173.2 0.0 1.3e-50 171.7 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CCD23093.1 - 0.0011 17.7 0.0 0.0023 16.7 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V CTP_transf_2 PF01467.21 CCD23094.1 - 7.8e-15 55.2 0.0 1.3e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase MA3 PF02847.12 CCD23095.1 - 1.2e-16 60.3 0.5 8.2e-16 57.7 0.0 2.8 3 0 0 3 3 3 1 MA3 domain MIF4G PF02854.14 CCD23095.1 - 6.8e-13 48.5 9.8 6.8e-13 48.5 6.8 2.5 2 0 0 2 2 2 1 MIF4G domain Glyco_hydro_17 PF00332.13 CCD23096.1 - 6.7e-10 38.4 0.6 6.7e-10 38.4 0.4 2.5 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 G-patch PF01585.18 CCD23097.1 - 6.7e-12 44.9 0.2 1.7e-11 43.6 0.1 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CCD23097.1 - 0.00017 21.3 0.2 0.00017 21.3 0.1 4.3 3 1 0 3 3 2 1 DExH-box splicing factor binding site TFIIF_alpha PF05793.7 CCD23097.1 - 0.0078 14.6 39.1 0.011 14.1 27.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.9 CCD23097.1 - 0.034 12.2 25.7 0.05 11.6 17.8 1.3 1 0 0 1 1 1 0 CDC45-like protein RRXRR PF14239.1 CCD23097.1 - 0.058 12.8 8.6 0.11 11.9 6.0 1.4 1 0 0 1 1 1 0 RRXRR protein DIRP PF06584.8 CCD23097.1 - 0.073 12.9 8.7 0.13 12.1 6.1 1.4 1 0 0 1 1 1 0 DIRP YL1 PF05764.8 CCD23097.1 - 0.25 10.9 42.4 0.48 9.9 29.4 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Hid1 PF12722.2 CCD23097.1 - 0.76 7.3 24.3 0.96 7.0 16.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 CCD23097.1 - 3.9 6.3 5.4 6.3 5.7 3.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4407 PF14362.1 CCD23097.1 - 6.3 5.6 14.9 8.6 5.2 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SOBP PF15279.1 CCD23097.1 - 6.4 7.0 13.6 9 6.5 9.4 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein ABC_membrane PF00664.18 CCD23098.1 - 2.4e-76 256.7 41.6 2.5e-41 141.9 10.2 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCD23098.1 - 2.4e-47 160.6 5.7 3.4e-29 101.8 0.0 3.9 3 1 0 3 3 2 2 ABC transporter SMC_N PF02463.14 CCD23098.1 - 1.1e-09 37.8 0.4 0.0091 15.2 0.0 4.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCD23098.1 - 2.3e-07 31.6 0.1 0.027 15.2 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCD23098.1 - 5.3e-07 29.0 0.9 0.026 14.0 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CCD23098.1 - 1.6e-06 28.3 20.0 1.2e-05 25.4 0.0 6.3 3 2 0 3 3 3 1 AAA domain AAA_23 PF13476.1 CCD23098.1 - 2.7e-06 27.8 23.3 0.0045 17.3 4.0 4.6 4 1 0 4 4 4 2 AAA domain DUF258 PF03193.11 CCD23098.1 - 3.5e-05 23.0 0.1 0.1 11.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 CCD23098.1 - 6.2e-05 22.0 0.2 0.01 14.7 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.1 CCD23098.1 - 0.00012 22.1 2.0 0.86 9.7 0.4 3.5 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 CCD23098.1 - 0.00049 20.5 0.1 0.88 10.0 0.0 3.0 2 0 0 2 2 2 1 Miro-like protein AAA_30 PF13604.1 CCD23098.1 - 0.00061 19.4 0.7 0.53 9.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CCD23098.1 - 0.00061 19.7 2.8 0.18 11.7 0.0 3.2 3 0 0 3 3 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.7 CCD23098.1 - 0.00069 18.7 0.0 0.07 12.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 CCD23098.1 - 0.0014 18.1 0.1 0.76 9.2 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_33 PF13671.1 CCD23098.1 - 0.0035 17.2 0.0 0.34 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCD23098.1 - 0.0037 16.6 0.0 1.2 8.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 CCD23098.1 - 0.0038 16.7 0.0 3.4 7.1 0.0 2.9 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 CCD23098.1 - 0.011 16.0 10.8 0.035 14.4 0.0 4.5 5 0 0 5 5 4 0 AAA domain AAA_5 PF07728.9 CCD23098.1 - 0.013 15.2 0.1 2.8 7.6 0.0 3.6 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 CCD23098.1 - 0.013 14.9 0.4 3.7 7.0 0.0 3.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CCD23098.1 - 0.015 15.5 0.1 14 5.8 0.0 3.7 4 0 0 4 4 3 0 RNA helicase UPF0079 PF02367.12 CCD23098.1 - 0.015 14.8 0.3 0.13 11.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 CCD23098.1 - 0.025 14.0 0.4 2.8 7.3 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA PF00004.24 CCD23098.1 - 0.031 14.4 2.0 0.36 11.0 0.0 3.5 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCD23098.1 - 0.055 13.4 1.0 1.3 8.9 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 CCD23098.1 - 0.068 12.8 0.2 6.6 6.4 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CCD23098.1 - 0.11 12.3 0.2 4.5 7.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CCD23098.1 - 0.3 10.8 12.0 0.36 10.6 0.0 4.0 4 0 0 4 4 3 0 Dynamin family Glyco_hydro_17 PF00332.13 CCD23099.1 - 1.7e-66 224.3 3.1 2e-66 224.1 2.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 SURF4 PF02077.10 CCD23100.1 - 4.3e-96 321.3 14.2 5.3e-96 321.0 9.8 1.0 1 0 0 1 1 1 1 SURF4 family DoxX PF07681.7 CCD23100.1 - 0.41 11.0 15.6 0.32 11.4 2.5 3.4 2 1 1 3 3 3 0 DoxX DUF1212 PF06738.7 CCD23100.1 - 5.6 6.3 11.0 2.1 7.8 2.2 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1212) DnaJ PF00226.26 CCD23101.1 - 1.3e-17 63.2 0.3 1.3e-17 63.2 0.2 2.6 3 0 0 3 3 3 1 DnaJ domain RNase_T PF00929.19 CCD23103.1 - 1.3e-28 100.3 0.0 3.5e-28 98.9 0.0 1.8 1 0 0 1 1 1 1 Exonuclease Rtt102p PF09510.5 CCD23104.1 - 3.1e-28 98.3 7.0 3.1e-28 98.3 4.8 2.7 2 2 0 2 2 2 1 Rtt102p-like transcription regulator protein DDE_1 PF03184.14 CCD23105.1 - 5.2e-11 42.0 1.2 2.8e-10 39.6 0.9 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF2406 PF10295.4 CCD23107.1 - 3.8e-19 68.9 0.1 8.9e-19 67.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) YbaB_DNA_bd PF02575.11 CCD23107.1 - 0.11 12.3 0.1 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family gag_pre-integrs PF13976.1 CCD23108.1 - 0.0056 16.2 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain RVP PF00077.15 CCD23108.1 - 0.046 13.6 0.1 0.42 10.5 0.0 2.5 2 1 0 2 2 2 0 Retroviral aspartyl protease UBN2 PF14223.1 CCD23108.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 CCD23108.1 - 0.35 10.5 1.9 0.88 9.2 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle RVT_2 PF07727.9 CCD23109.1 - 2.7e-11 42.9 0.0 5.2e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF2361 PF10153.4 CCD23110.1 - 3.4e-36 123.9 17.3 3.4e-36 123.9 12.0 2.7 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) Sec63 PF02889.11 CCD23111.1 - 3.3e-134 447.0 3.7 7e-92 307.9 0.0 2.7 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.24 CCD23111.1 - 2.2e-53 180.2 1.1 1.1e-27 96.5 0.4 4.3 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 CCD23111.1 - 1.4e-20 73.9 0.7 8.6e-10 38.7 0.0 3.2 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCD23111.1 - 3.5e-18 65.2 0.1 5.1e-08 32.6 0.0 3.2 4 0 0 4 4 4 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCD23111.1 - 7.2e-08 31.5 0.1 0.00066 18.5 0.1 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain AAA PF00004.24 CCD23111.1 - 1.8e-06 28.1 1.7 0.33 11.1 0.0 4.6 4 2 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 CCD23111.1 - 1.1e-05 24.7 0.0 0.03 13.5 0.0 2.8 2 0 0 2 2 2 2 PhoH-like protein IstB_IS21 PF01695.12 CCD23111.1 - 1.7e-05 24.3 0.3 0.093 12.1 0.0 4.0 5 0 0 5 5 5 2 IstB-like ATP binding protein AAA_22 PF13401.1 CCD23111.1 - 3.4e-05 23.9 3.9 0.079 13.1 0.1 4.7 4 2 0 4 4 4 2 AAA domain AAA_19 PF13245.1 CCD23111.1 - 4.7e-05 23.0 0.0 0.033 13.9 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain T2SE PF00437.15 CCD23111.1 - 0.00039 19.4 0.0 0.2 10.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 CCD23111.1 - 0.011 15.1 0.2 22 4.3 0.0 4.0 3 1 0 4 4 4 0 AAA-like domain Zeta_toxin PF06414.7 CCD23111.1 - 0.079 12.0 0.0 19 4.2 0.0 3.2 3 0 0 3 3 3 0 Zeta toxin AAA PF00004.24 CCD23112.1 - 1.3e-51 174.2 0.0 1.1e-42 145.3 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCD23112.1 - 2.8e-07 30.6 0.0 2.4e-05 24.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCD23112.1 - 9.6e-07 28.9 0.1 4.6e-05 23.4 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCD23112.1 - 1.2e-06 28.6 0.5 0.0011 19.1 0.1 4.0 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCD23112.1 - 1.8e-06 27.4 0.0 0.00031 20.2 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 CCD23112.1 - 8.9e-06 25.8 0.0 0.14 12.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 CCD23112.1 - 1.4e-05 24.8 0.1 0.00058 19.5 0.0 3.5 4 1 0 4 4 3 1 AAA domain (dynein-related subfamily) Bromodomain PF00439.20 CCD23112.1 - 5.9e-05 22.9 0.7 0.0017 18.2 0.1 3.0 2 0 0 2 2 2 1 Bromodomain AAA_14 PF13173.1 CCD23112.1 - 0.00014 21.7 0.0 0.0071 16.2 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCD23112.1 - 0.00018 21.2 0.0 0.024 14.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 CCD23112.1 - 0.00021 20.1 0.0 0.014 14.1 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus Sigma54_activat PF00158.21 CCD23112.1 - 0.00032 20.2 0.0 0.63 9.5 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 CCD23112.1 - 0.0023 17.3 0.4 0.025 13.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCD23112.1 - 0.0052 15.9 0.0 0.099 11.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI T2SE PF00437.15 CCD23112.1 - 0.0056 15.6 0.2 5.4 5.8 0.0 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein RNA_helicase PF00910.17 CCD23112.1 - 0.0078 16.3 0.0 0.042 14.0 0.0 2.3 3 0 0 3 3 1 1 RNA helicase AAA_33 PF13671.1 CCD23112.1 - 0.0085 15.9 0.0 0.03 14.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 CCD23112.1 - 0.0096 15.1 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein ABC_tran PF00005.22 CCD23112.1 - 0.0098 16.1 6.5 0.035 14.4 0.0 3.8 4 0 0 4 4 3 1 ABC transporter AAA_17 PF13207.1 CCD23112.1 - 0.017 15.9 0.0 0.017 15.9 0.0 5.6 6 1 0 6 6 5 0 AAA domain AAA_3 PF07726.6 CCD23112.1 - 0.024 14.2 0.0 0.067 12.7 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CCD23112.1 - 0.024 14.4 0.0 0.024 14.4 0.0 3.4 5 0 0 5 5 3 0 Type III restriction enzyme, res subunit AAA_30 PF13604.1 CCD23112.1 - 0.045 13.3 0.0 0.12 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCD23112.1 - 0.13 12.5 0.0 0.13 12.5 0.0 4.4 4 2 1 5 5 3 0 AAA domain DnaJ_CXXCXGXG PF00684.14 CCD23113.1 - 6.3e-05 22.9 6.1 0.086 12.9 0.5 2.7 2 1 0 2 2 2 2 DnaJ central domain APC_CDC26 PF10471.4 CCD23113.1 - 0.0069 17.0 3.6 0.013 16.2 2.5 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 C1_2 PF03107.11 CCD23113.1 - 0.21 11.7 2.5 2.7 8.1 0.1 2.5 2 0 0 2 2 2 0 C1 domain HypA PF01155.14 CCD23113.1 - 0.31 10.7 1.6 2.2 7.9 0.3 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family PAT1 PF09770.4 CCD23113.1 - 3.7 5.6 9.9 3.9 5.6 6.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GTP_cyclohydroI PF01227.17 CCD23114.1 - 8.4e-77 256.4 0.6 1e-76 256.2 0.5 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CCD23114.1 - 8.2e-06 25.6 0.0 2.8e-05 23.9 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein OmpH PF03938.9 CCD23114.1 - 0.14 12.0 0.4 1.9 8.4 0.0 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) PhoD PF09423.5 CCD23115.1 - 7.3e-05 21.5 0.0 0.00016 20.4 0.0 1.5 1 1 0 1 1 1 1 PhoD-like phosphatase XkdN PF08890.6 CCD23115.1 - 0.048 13.3 0.0 6.5 6.4 0.0 2.4 2 0 0 2 2 2 0 Phage XkdN-like protein DUF2424 PF10340.4 CCD23116.1 - 7.4e-95 317.7 2.6 8.3e-95 317.5 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 CCD23116.1 - 7.3e-13 48.5 0.0 9.5e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 CCD23117.1 - 1.8e-86 290.1 0.0 2e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 CCD23117.1 - 8.5e-16 58.1 0.0 1.1e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCD23117.1 - 0.026 14.2 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCD23117.1 - 0.079 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Kdo PF06293.9 CCD23118.1 - 4.1e-07 29.2 0.0 7e-07 28.5 0.0 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CCD23118.1 - 1.2e-05 24.6 0.0 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 CCD23118.1 - 4.4e-05 22.8 0.0 6.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 CCD23118.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase EcKinase PF02958.15 CCD23118.1 - 0.063 12.4 0.4 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Ecdysteroid kinase DUF1679 PF07914.6 CCD23118.1 - 0.13 10.8 0.1 0.18 10.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) Adaptin_N PF01602.15 CCD23119.1 - 3.2e-100 335.9 8.5 3.9e-100 335.6 5.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCD23119.1 - 4e-09 36.5 8.3 6.4e-05 22.8 0.0 3.7 4 0 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CCD23119.1 - 1.2e-08 34.2 0.6 0.0064 16.4 0.0 4.9 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 CCD23119.1 - 2.2e-08 34.2 0.4 7e-07 29.4 0.0 3.5 3 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 CCD23119.1 - 0.00054 20.3 0.7 6.9 7.3 0.0 4.5 4 1 1 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CCD23119.1 - 0.0057 17.0 0.4 0.48 10.8 0.0 3.7 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region RasGEF_N_2 PF14663.1 CCD23119.1 - 0.019 14.8 0.5 16 5.4 0.1 3.5 3 1 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DUF2457 PF10446.4 CCD23119.1 - 3.4 6.2 24.5 5.9 5.5 17.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 CCD23119.1 - 4.7 6.8 15.5 8.6 5.9 10.7 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein MFS_1 PF07690.11 CCD23120.1 - 2.1e-30 105.6 28.3 2.2e-30 105.5 19.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Peptidase_C26 PF07722.8 CCD23120.1 - 0.057 12.8 0.2 0.57 9.5 0.1 2.1 2 0 0 2 2 2 0 Peptidase C26 XPG_N PF00752.12 CCD23121.1 - 1.6e-35 121.3 0.0 4.1e-35 120.0 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCD23121.1 - 1.3e-24 86.0 0.0 6.9e-24 83.7 0.0 2.4 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CCD23121.1 - 0.0045 17.2 1.7 0.012 15.8 0.0 2.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Mito_carr PF00153.22 CCD23122.1 - 4.1e-62 205.9 1.4 2.6e-22 78.3 0.1 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2702 PF10863.3 CCD23123.1 - 5.7e-53 178.4 9.2 5.7e-53 178.4 6.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2702) DUF3857 PF12969.2 CCD23123.1 - 0.038 13.5 0.2 0.32 10.5 0.0 2.1 1 1 1 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3857) FLO_LFY PF01698.11 CCD23123.1 - 0.058 12.2 0.4 0.058 12.2 0.3 2.3 2 1 1 3 3 3 0 Floricaula / Leafy protein DEAD PF00270.24 CCD23124.1 - 3.5e-40 137.2 0.0 3.4e-39 134.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD23124.1 - 2.5e-26 91.3 0.1 6.6e-26 89.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD23124.1 - 0.004 17.0 0.5 0.013 15.2 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Dynactin_p22 PF07426.6 CCD23124.1 - 0.042 13.1 1.1 0.16 11.2 0.0 2.1 2 0 0 2 2 2 0 Dynactin subunit p22 Engrail_1_C_sig PF10525.4 CCD23125.1 - 0.045 12.8 0.0 0.09 11.9 0.0 1.5 1 0 0 1 1 1 0 Engrailed homeobox C-terminal signature domain Phage_Nu1 PF07471.7 CCD23125.1 - 0.14 11.6 0.7 0.27 10.6 0.1 1.8 2 0 0 2 2 2 0 Phage DNA packaging protein Nu1 Oxidored_FMN PF00724.15 CCD23126.1 - 8e-123 409.7 0.0 9.2e-123 409.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RRM_1 PF00076.17 CCD23127.1 - 7.4e-26 89.5 1.0 1.8e-07 30.6 0.1 5.7 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD23127.1 - 8.2e-18 64.1 0.1 1.2e-06 28.3 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD23127.1 - 3.2e-09 36.5 3.5 0.0029 17.4 0.6 4.6 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vir_act_alpha_C PF10400.4 CCD23127.1 - 0.062 13.6 0.2 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Virulence activator alpha C-term HSF_DNA-bind PF00447.12 CCD23128.1 - 5.9e-26 90.6 3.5 2.5e-25 88.6 2.4 2.2 1 0 0 1 1 1 1 HSF-type DNA-binding Glucosamine_iso PF01182.15 CCD23129.1 - 7.2e-08 32.3 0.0 9.9e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase CPDase PF07823.6 CCD23130.1 - 1.2e-63 214.2 0.4 1.3e-63 214.0 0.3 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 CCD23130.1 - 0.0017 18.1 0.0 0.0045 16.7 0.0 1.7 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.4 CCD23130.1 - 0.0032 17.1 0.3 0.004 16.8 0.2 1.2 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain TFIIB PF00382.14 CCD23131.1 - 1.2e-53 178.8 0.8 5.3e-27 93.4 0.1 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 CCD23131.1 - 6.4e-29 100.0 2.1 6.4e-29 100.0 1.4 3.1 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 CCD23131.1 - 4e-09 35.6 2.8 4e-09 35.6 2.0 1.7 2 0 0 2 2 2 1 TFIIB zinc-binding Cyclin_N PF00134.18 CCD23131.1 - 2.2e-05 24.0 0.3 0.047 13.2 0.1 2.6 2 0 0 2 2 2 2 Cyclin, N-terminal domain An_peroxidase PF03098.10 CCD23131.1 - 0.0047 15.3 0.6 0.0082 14.5 0.4 1.5 1 1 0 1 1 1 1 Animal haem peroxidase SDA1 PF05285.7 CCD23132.1 - 1.6e-101 339.8 37.9 1.6e-101 339.8 26.3 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 CCD23132.1 - 7.2e-20 71.0 0.2 1.8e-19 69.7 0.1 1.7 1 0 0 1 1 1 1 NUC130/3NT domain ATP-grasp_2 PF08442.5 CCD23133.1 - 2.1e-67 226.4 0.3 3.5e-67 225.7 0.2 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CCD23133.1 - 4e-26 91.4 0.1 7.3e-26 90.5 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 CCD23133.1 - 1.6e-05 24.2 0.1 3.8e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 CCD23133.1 - 0.0016 18.0 0.2 0.0037 16.8 0.1 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 CCD23133.1 - 0.038 13.7 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain TrkA_N PF02254.13 CCD23133.1 - 0.051 13.5 0.2 6.8 6.7 0.0 3.0 3 0 0 3 3 3 0 TrkA-N domain PTS_IIB PF02302.12 CCD23133.1 - 0.28 11.7 1.7 1.2 9.6 0.1 2.6 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit MPC PF03650.8 CCD23134.1 - 9.3e-49 164.3 0.2 1.1e-48 164.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF3210 PF11489.3 CCD23135.1 - 3.3e-16 59.1 63.2 3.3e-16 59.1 43.8 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF3210) Helicase_C PF00271.26 CCD23136.1 - 1.9e-19 69.3 0.1 1.3e-18 66.6 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD23136.1 - 3e-19 69.1 0.0 4.7e-18 65.2 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CCD23136.1 - 1.1e-17 64.4 0.0 1.1e-17 64.4 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCD23136.1 - 0.073 13.2 0.0 0.31 11.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain CAP_GLY PF01302.20 CCD23137.1 - 4.3e-15 55.1 0.0 9.3e-15 54.0 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 CCD23137.1 - 2.5e-14 52.5 35.2 1.5e-05 24.4 1.8 5.4 4 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCD23137.1 - 4.9e-10 39.0 42.9 3.5e-06 26.6 4.2 4.9 3 1 3 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 CCD23137.1 - 1e-09 37.0 33.2 0.59 10.3 0.1 9.6 9 0 0 9 9 9 6 Leucine Rich Repeat LRR_7 PF13504.1 CCD23137.1 - 4.2e-06 26.0 24.0 0.45 10.9 0.2 8.7 8 0 0 8 8 8 2 Leucine rich repeat LRR_6 PF13516.1 CCD23137.1 - 9.4e-06 25.1 34.6 0.51 10.5 0.1 8.8 8 1 1 9 9 9 5 Leucine Rich repeat GRASP55_65 PF04495.9 CCD23138.1 - 0.00023 21.1 0.0 0.00042 20.3 0.0 1.3 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ PF00595.19 CCD23138.1 - 0.00025 21.1 0.2 0.00048 20.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CCD23138.1 - 0.0048 16.7 0.1 0.0091 15.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain Gti1_Pac2 PF09729.4 CCD23139.1 - 2e-46 157.9 0.0 5.1e-46 156.6 0.0 1.7 2 0 0 2 2 2 1 Gti1/Pac2 family Mito_carr PF00153.22 CCD23140.1 - 1.9e-70 232.6 2.0 2.3e-23 81.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1454 PF07305.7 CCD23140.1 - 0.0093 15.0 0.0 0.46 9.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1454) Thioredoxin PF00085.15 CCD23141.1 - 3.1e-27 94.2 0.6 4.1e-21 74.6 0.0 4.5 5 1 1 6 6 6 3 Thioredoxin Thioredoxin_6 PF13848.1 CCD23141.1 - 4.1e-05 23.4 7.3 0.00018 21.3 0.6 3.4 3 1 1 4 4 4 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCD23141.1 - 0.0066 16.5 2.9 0.07 13.2 0.1 4.0 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_4 PF13462.1 CCD23141.1 - 0.13 12.2 2.1 0.23 11.4 0.1 2.4 3 0 0 3 3 3 0 Thioredoxin SNARE PF05739.14 CCD23142.1 - 1.7e-09 37.2 0.9 3e-09 36.4 0.4 1.6 1 1 1 2 2 2 1 SNARE domain Use1 PF09753.4 CCD23142.1 - 5.5e-06 26.0 0.8 6.4e-06 25.7 0.6 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 DNA_ligase_IV PF11411.3 CCD23142.1 - 0.04 13.6 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 DNA ligase IV Sipho_Gp157 PF05565.6 CCD23142.1 - 0.055 13.0 0.1 0.073 12.6 0.1 1.1 1 0 0 1 1 1 0 Siphovirus Gp157 RmuC PF02646.11 CCD23142.1 - 0.074 11.8 0.4 0.1 11.4 0.3 1.2 1 0 0 1 1 1 0 RmuC family Sec20 PF03908.8 CCD23142.1 - 0.16 11.7 3.0 0.19 11.4 0.6 1.9 1 1 1 2 2 2 0 Sec20 Synaptobrevin PF00957.16 CCD23142.1 - 0.76 9.4 5.5 2.3 7.8 3.8 1.9 1 1 0 1 1 1 0 Synaptobrevin Syja_N PF02383.13 CCD23143.1 - 3.1e-59 200.3 0.7 5.8e-59 199.4 0.5 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CCD23143.1 - 1.2e-20 74.5 0.0 1.8e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Laminin_II PF06009.7 CCD23144.1 - 0.00021 21.0 1.2 0.00023 20.9 0.8 1.1 1 0 0 1 1 1 1 Laminin Domain II HSBP1 PF06825.7 CCD23144.1 - 0.00065 19.2 3.1 0.0011 18.4 2.2 1.4 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Spectrin PF00435.16 CCD23144.1 - 0.0039 17.4 1.8 0.0046 17.2 1.3 1.2 1 0 0 1 1 1 1 Spectrin repeat Prefoldin_2 PF01920.15 CCD23144.1 - 0.0045 16.7 2.3 0.0069 16.1 1.6 1.4 1 0 0 1 1 1 1 Prefoldin subunit Nnf1 PF03980.9 CCD23144.1 - 0.013 15.5 0.6 0.017 15.1 0.4 1.2 1 0 0 1 1 1 0 Nnf1 Prefoldin PF02996.12 CCD23144.1 - 0.015 14.9 1.9 0.021 14.4 1.3 1.3 1 0 0 1 1 1 0 Prefoldin subunit Exonuc_VII_S PF02609.11 CCD23144.1 - 0.017 14.8 0.4 0.056 13.2 0.0 2.0 1 1 1 2 2 2 0 Exonuclease VII small subunit DUF4061 PF13270.1 CCD23144.1 - 0.022 14.8 2.7 0.031 14.3 1.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) CHASE3 PF05227.8 CCD23144.1 - 0.022 14.4 0.1 0.025 14.2 0.1 1.1 1 0 0 1 1 1 0 CHASE3 domain Sec2p PF06428.6 CCD23144.1 - 0.025 14.4 4.4 0.032 14.0 3.0 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p HR1 PF02185.11 CCD23144.1 - 0.028 14.1 2.2 0.036 13.8 1.5 1.2 1 0 0 1 1 1 0 Hr1 repeat LXG PF04740.7 CCD23144.1 - 0.03 14.1 2.0 0.032 14.0 1.4 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF948 PF06103.6 CCD23144.1 - 0.03 14.1 0.2 0.042 13.6 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Cmyb_C PF09316.5 CCD23144.1 - 0.032 13.9 0.3 0.034 13.8 0.2 1.1 1 0 0 1 1 1 0 C-myb, C-terminal DUF3486 PF11985.3 CCD23144.1 - 0.038 14.0 0.4 0.045 13.8 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3486) Prefoldin_3 PF13758.1 CCD23144.1 - 0.039 13.7 0.5 0.065 13.0 0.3 1.4 1 1 0 1 1 1 0 Prefoldin subunit DUF1759 PF03564.10 CCD23144.1 - 0.044 13.5 0.2 0.065 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF972 PF06156.8 CCD23144.1 - 0.052 13.9 1.1 0.072 13.4 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF972) SlyX PF04102.7 CCD23144.1 - 0.06 13.7 1.5 0.096 13.0 1.1 1.4 1 0 0 1 1 1 0 SlyX Spc24 PF08286.6 CCD23144.1 - 0.084 12.5 6.0 0.12 12.1 4.2 1.2 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 bZIP_2 PF07716.10 CCD23144.1 - 0.1 12.4 5.3 0.17 11.7 3.7 1.3 1 0 0 1 1 1 0 Basic region leucine zipper IncA PF04156.9 CCD23144.1 - 0.11 12.0 2.5 0.1 12.1 1.7 1.1 1 0 0 1 1 1 0 IncA protein DUF2802 PF10975.3 CCD23144.1 - 0.13 12.0 0.8 2.2 8.1 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2802) PhoU PF01895.14 CCD23144.1 - 0.14 12.6 1.3 0.18 12.2 0.9 1.2 1 0 0 1 1 1 0 PhoU domain DUF342 PF03961.8 CCD23144.1 - 0.16 10.3 1.9 0.18 10.1 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3373 PF11853.3 CCD23144.1 - 0.17 10.4 0.8 0.19 10.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) YvrJ PF12841.2 CCD23144.1 - 0.2 10.9 0.6 0.41 9.9 0.2 1.7 1 1 0 1 1 1 0 YvrJ protein family V_ATPase_I PF01496.14 CCD23144.1 - 0.21 9.3 2.7 0.23 9.3 1.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family APG6 PF04111.7 CCD23144.1 - 0.22 10.5 5.8 0.18 10.8 3.6 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 FlaC_arch PF05377.6 CCD23144.1 - 0.25 11.2 2.2 0.49 10.3 1.5 1.5 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) Viral_P18 PF04521.8 CCD23144.1 - 0.31 10.4 1.6 0.39 10.1 1.1 1.2 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein XhlA PF10779.4 CCD23144.1 - 0.47 10.4 3.5 0.62 10.0 2.5 1.3 1 0 0 1 1 1 0 Haemolysin XhlA DUF4588 PF15251.1 CCD23145.1 - 6.5e-07 29.5 6.1 1.1e-06 28.8 4.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Baculo_VP91_N PF08475.5 CCD23145.1 - 0.011 15.1 6.4 0.022 14.0 1.2 2.0 2 0 0 2 2 2 0 Viral capsid protein 91 N-terminal GFO_IDH_MocA PF01408.17 CCD23146.1 - 3.4e-05 24.3 0.0 5.4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCD23146.1 - 0.00019 21.1 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain zf-HIT PF04438.11 CCD23147.1 - 4.6e-12 45.3 14.7 6.2e-12 44.9 6.9 2.2 2 0 0 2 2 2 1 HIT zinc finger YL1_C PF08265.6 CCD23147.1 - 0.001 18.5 0.0 0.0027 17.2 0.0 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Plasmod_Pvs28 PF06247.6 CCD23147.1 - 0.003 17.1 3.6 0.0038 16.8 2.5 1.2 1 0 0 1 1 1 1 Plasmodium ookinete surface protein Pvs28 zf-Mss51 PF13824.1 CCD23147.1 - 0.025 14.4 4.8 0.025 14.4 3.3 1.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-MYND PF01753.13 CCD23147.1 - 0.029 14.2 7.4 0.029 14.2 5.1 1.7 2 0 0 2 2 2 0 MYND finger Shisa PF13908.1 CCD23147.1 - 0.064 13.4 3.0 0.088 12.9 2.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator YrbL-PhoP_reg PF10707.4 CCD23147.1 - 0.11 11.8 0.2 0.13 11.6 0.1 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-B_box PF00643.19 CCD23147.1 - 0.13 12.1 10.8 0.13 12.2 4.5 2.1 2 0 0 2 2 2 0 B-box zinc finger PolC_DP2 PF03833.8 CCD23147.1 - 0.27 8.8 2.2 0.3 8.6 1.5 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF1610 PF07754.6 CCD23147.1 - 1.6 8.9 6.1 5.2 7.2 4.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF1610) zf-CCHC PF00098.18 CCD23148.1 - 3.8e-05 23.4 3.3 5.8e-05 22.8 2.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CCD23148.1 - 0.019 14.6 1.0 0.032 13.9 0.7 1.4 1 0 0 1 1 1 0 Zinc knuckle RPA_interact_N PF14766.1 CCD23148.1 - 0.055 12.9 0.1 0.12 11.8 0.1 1.6 1 0 0 1 1 1 0 Replication protein A interacting N-terminal zf-CCHC_4 PF14392.1 CCD23148.1 - 0.16 11.6 1.1 0.34 10.6 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle Peptidase_A2B PF12384.3 CCD23149.1 - 1.8e-25 89.3 0.3 2.5e-25 88.8 0.2 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.1 CCD23149.1 - 2.3e-07 31.2 0.0 4.6e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CCD23149.1 - 0.001 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CCD23149.1 - 0.018 14.9 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Retroviral aspartyl protease DUF1758 PF05585.7 CCD23149.1 - 0.046 13.2 0.0 0.077 12.5 0.0 1.5 1 1 0 1 1 1 0 Putative peptidase (DUF1758) RVP_2 PF08284.6 CCD23149.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease Retrotrans_gag PF03732.12 CCD23150.1 - 1.4e-11 44.2 0.0 2.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CCD23150.1 - 0.00032 20.4 2.6 0.00058 19.6 1.8 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 CCD23150.1 - 0.00033 20.0 5.2 0.00068 19.0 3.6 1.5 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.1 CCD23150.1 - 0.011 15.4 2.3 0.022 14.4 1.6 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF962 PF06127.6 CCD23150.1 - 0.16 11.9 0.5 3.1 7.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF962) LRR_6 PF13516.1 CCD23153.1 - 0.34 11.1 18.3 19 5.7 0.1 7.3 7 0 0 7 7 7 0 Leucine Rich repeat LRR_4 PF12799.2 CCD23153.1 - 3.8 7.2 18.2 6.6 6.4 0.3 5.2 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) FAD_binding_2 PF00890.19 CCD23154.1 - 4.2e-69 233.3 0.0 5.3e-69 233.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CCD23154.1 - 4.2e-07 30.0 0.5 0.00052 19.9 0.2 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCD23154.1 - 8.3e-06 25.7 0.0 2.6e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCD23154.1 - 3e-05 24.1 0.1 0.00027 21.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCD23154.1 - 3.8e-05 22.9 1.0 0.0048 16.0 0.1 2.4 2 0 0 2 2 2 2 Thi4 family DAO PF01266.19 CCD23154.1 - 9.1e-05 21.5 0.0 0.0009 18.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 CCD23154.1 - 0.00088 19.0 0.1 0.0031 17.2 0.1 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding HI0933_like PF03486.9 CCD23154.1 - 0.074 11.5 6.1 0.044 12.2 1.1 2.6 2 1 0 2 2 2 0 HI0933-like protein DUF3659 PF12396.3 CCD23154.1 - 0.1 12.3 0.6 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) FAD_binding_3 PF01494.14 CCD23154.1 - 0.12 11.4 0.2 0.19 10.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Beta_elim_lyase PF01212.16 CCD23155.1 - 5e-77 258.9 0.0 6.1e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Isy1 PF06246.7 CCD23156.1 - 1.2e-43 149.3 20.3 2.1e-43 148.6 14.1 1.3 1 1 0 1 1 1 1 Isy1-like splicing family NAD_kinase PF01513.16 CCD23157.1 - 1.1e-77 260.5 0.4 1.6e-77 260.0 0.0 1.4 2 0 0 2 2 2 1 ATP-NAD kinase Cytochrom_C PF00034.16 CCD23158.1 - 1.5e-09 38.5 0.1 2.9e-09 37.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CCD23158.1 - 8.3e-07 29.0 1.0 6.3e-06 26.2 0.7 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CCD23158.1 - 0.026 13.9 2.5 0.34 10.3 1.7 2.1 1 1 0 1 1 1 0 Cytochrome c-550 domain Anp1 PF03452.9 CCD23159.1 - 6.6e-117 389.4 0.0 1.2e-116 388.6 0.0 1.3 1 0 0 1 1 1 1 Anp1 eIF-5a PF01287.15 CCD23160.1 - 4.2e-27 93.8 0.5 5.8e-27 93.4 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CCD23160.1 - 7.7e-05 22.2 0.8 0.00014 21.4 0.6 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 CCD23160.1 - 0.0041 16.9 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain TgMIC1 PF11476.3 CCD23160.1 - 0.019 14.5 0.1 0.07 12.6 0.0 1.8 1 1 1 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 PWWP PF00855.12 CCD23161.1 - 2.9e-20 72.2 0.4 2.9e-20 72.2 0.3 2.3 2 1 0 2 2 2 1 PWWP domain SRF-TF PF00319.13 CCD23162.1 - 2.8e-25 87.2 0.3 4.8e-25 86.5 0.2 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PI3K_1B_p101 PF10486.4 CCD23162.1 - 0.0017 16.0 0.4 0.0018 15.9 0.3 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF605 PF04652.11 CCD23162.1 - 1.2 8.4 25.7 1.7 7.9 17.8 1.1 1 0 0 1 1 1 0 Vta1 like Spt5_N PF11942.3 CCD23162.1 - 9 6.9 16.4 4.8 7.8 4.6 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal SRF-TF PF00319.13 CCD23163.1 - 3.7e-24 83.6 0.2 7.4e-24 82.7 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CENP-T PF15511.1 CCD23163.1 - 0.01 15.1 5.5 0.013 14.7 3.8 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T SGT1 PF07093.6 CCD23163.1 - 0.23 9.8 8.3 0.28 9.5 5.8 1.1 1 0 0 1 1 1 0 SGT1 protein Daxx PF03344.10 CCD23163.1 - 0.57 8.6 17.0 0.75 8.2 11.8 1.2 1 0 0 1 1 1 0 Daxx Family COPI_C PF06957.6 CCD23163.1 - 1.6 7.1 7.9 2.1 6.7 5.5 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.7 CCD23163.1 - 4.8 4.9 20.3 6.4 4.5 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family Aldo_ket_red PF00248.16 CCD23164.1 - 6.5e-48 162.9 0.0 7.8e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Bap31 PF05529.7 CCD23165.1 - 8.8e-33 113.3 8.2 1.3e-32 112.7 5.7 1.3 1 1 0 1 1 1 1 B-cell receptor-associated protein 31-like MBT PF02820.13 CCD23165.1 - 0.014 15.2 0.1 0.057 13.3 0.0 1.9 2 0 0 2 2 2 0 mbt repeat YqzM PF14141.1 CCD23165.1 - 1.2 8.9 4.1 12 5.8 0.3 2.7 2 0 0 2 2 2 0 YqzM-like protein PC4 PF02229.11 CCD23166.1 - 1.3e-20 72.4 0.1 2.6e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) Phos_pyr_kin PF08543.7 CCD23166.1 - 0.057 12.5 0.5 0.08 12.1 0.3 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase SLBP_RNA_bind PF15247.1 CCD23166.1 - 0.6 9.9 5.4 0.31 10.8 2.0 1.9 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain Hid1 PF12722.2 CCD23166.1 - 2.2 5.8 12.9 2.6 5.6 8.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PLRV_ORF5 PF01690.12 CCD23166.1 - 3.1 6.8 21.6 4 6.4 15.0 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Rnk_N PF14760.1 CCD23166.1 - 3.9 7.6 8.7 0.22 11.6 0.4 2.3 2 0 0 2 2 2 0 Rnk N-terminus HMA PF00403.21 CCD23167.1 - 4.9e-07 29.7 0.1 1.1e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 CCD23167.1 - 1.3e-06 28.6 0.0 4.5e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) zf-C2H2 PF00096.21 CCD23168.1 - 8.4e-11 41.5 13.0 2.7e-05 24.2 2.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD23168.1 - 3.5e-10 39.4 12.9 9.3e-05 22.4 2.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD23168.1 - 3.2e-07 30.3 19.5 6e-06 26.2 2.4 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.10 CCD23168.1 - 0.0013 18.4 6.3 0.031 14.0 0.8 2.8 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_jaz PF12171.3 CCD23168.1 - 0.0041 17.2 10.7 0.014 15.4 2.2 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCD23168.1 - 0.0072 16.1 7.2 0.067 13.1 0.7 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CCD23168.1 - 0.0092 16.1 8.6 0.045 13.9 1.4 3.2 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CCD23168.1 - 0.011 15.7 4.4 0.022 14.8 3.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CCD23168.1 - 2.8 8.1 8.7 9.4 6.4 1.5 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Rhodanese PF00581.15 CCD23169.1 - 2.7e-12 47.0 0.0 6.3e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Peptidase_S26 PF10502.4 CCD23170.1 - 6.1e-05 22.5 0.0 0.0018 17.7 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.18 CCD23170.1 - 0.00017 21.1 0.1 0.00042 19.8 0.1 1.7 1 1 0 1 1 1 1 Peptidase S24-like DUF4137 PF13593.1 CCD23171.1 - 3.3e-117 391.0 12.2 3.9e-117 390.8 8.4 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) FCH PF00611.18 CCD23172.1 - 8.4e-15 54.7 0.3 8.4e-15 54.7 0.2 3.9 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 CCD23172.1 - 0.037 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain SH3_1 PF00018.23 CCD23172.1 - 0.067 12.5 0.0 0.17 11.3 0.0 1.7 1 0 0 1 1 1 0 SH3 domain DUF3812 PF12757.2 CCD23173.1 - 1.3e-27 96.2 0.4 1.3e-27 96.2 0.3 4.8 4 1 0 4 4 4 1 Protein of unknown function (DUF3812) Frag1 PF10277.4 CCD23174.1 - 2.1e-76 256.1 24.0 2.6e-76 255.8 16.7 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2207 PF09972.4 CCD23174.1 - 9.6 4.6 8.6 0.59 8.6 0.1 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) CUE PF02845.11 CCD23175.1 - 7.2e-05 22.1 0.1 7.2e-05 22.1 0.1 1.7 2 0 0 2 2 2 1 CUE domain Striatin PF08232.7 CCD23176.1 - 1.2e-25 90.3 13.1 7.5e-25 87.8 5.9 3.3 2 1 0 2 2 2 1 Striatin family WD40 PF00400.27 CCD23176.1 - 0.11 12.4 0.0 20 5.2 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat TAP42 PF04177.7 CCD23178.1 - 1.2e-88 297.3 24.1 1.4e-88 297.1 16.7 1.0 1 0 0 1 1 1 1 TAP42-like family DUF89 PF01937.14 CCD23179.1 - 1.6e-111 372.5 4.4 1.8e-111 372.4 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Pex2_Pex12 PF04757.9 CCD23180.1 - 5.7e-46 156.7 8.4 7.2e-46 156.4 5.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CCD23180.1 - 4.1e-07 29.9 6.8 7.6e-07 29.0 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCD23180.1 - 2.3e-06 27.1 4.1 3.6e-06 26.5 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCD23180.1 - 0.00082 19.1 4.8 0.0015 18.3 3.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 CCD23180.1 - 0.0019 18.0 8.5 0.0034 17.2 5.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CCD23180.1 - 0.0069 16.0 6.7 0.012 15.2 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 CCD23180.1 - 2 7.9 7.2 20 4.7 0.0 3.6 4 0 0 4 4 4 0 Rad50 zinc hook motif MitMem_reg PF13012.1 CCD23181.1 - 0.0098 15.9 3.1 0.027 14.5 1.5 2.1 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function dsrm PF00035.20 CCD23182.1 - 8.1e-09 35.9 0.0 1.8e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 CCD23182.1 - 9.2e-08 32.5 0.2 2.2e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease III domain Helicase_C PF00271.26 CCD23183.1 - 6.1e-11 42.0 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD23183.1 - 4.2e-10 39.3 0.0 9.9e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1492 PF07374.6 CCD23183.1 - 0.12 12.5 0.9 0.42 10.7 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) TrmE_N PF10396.4 CCD23184.1 - 2.6e-35 120.8 0.0 6.9e-35 119.4 0.0 1.8 2 0 0 2 2 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 CCD23184.1 - 7.7e-25 87.1 1.3 2.3e-24 85.6 0.9 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 CCD23184.1 - 7.6e-18 64.6 0.4 3.8e-16 59.2 0.0 3.0 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 CCD23184.1 - 8.5e-12 44.6 2.0 1.6e-11 43.7 1.4 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CCD23184.1 - 3.2e-10 39.7 2.8 1.2e-07 31.3 0.1 2.9 2 1 1 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 CCD23184.1 - 5.7e-08 33.2 2.3 1.1e-07 32.3 0.3 2.3 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCD23184.1 - 1.2e-05 24.6 1.9 0.0002 20.6 1.3 2.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCD23184.1 - 1.3e-05 24.6 0.3 2.9e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 Ras family DUF258 PF03193.11 CCD23184.1 - 2.2e-05 23.6 0.3 0.00014 21.1 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ArgK PF03308.11 CCD23184.1 - 0.00044 19.1 1.5 0.15 10.8 0.2 3.5 1 1 2 3 3 3 1 ArgK protein Dynamin_N PF00350.18 CCD23184.1 - 0.00074 19.3 1.7 0.00074 19.3 1.2 3.1 3 2 0 3 3 3 1 Dynamin family PduV-EutP PF10662.4 CCD23184.1 - 0.0014 18.1 2.5 0.82 9.1 0.2 3.3 3 0 0 3 3 3 2 Ethanolamine utilisation - propanediol utilisation Phage_CII PF05269.6 CCD23184.1 - 0.0095 15.9 0.0 0.6 10.1 0.0 3.2 2 0 0 2 2 2 1 Bacteriophage CII protein TAFH PF07531.9 CCD23184.1 - 0.012 15.2 1.4 0.048 13.2 0.1 2.3 2 0 0 2 2 2 0 NHR1 homology to TAF cobW PF02492.14 CCD23184.1 - 0.053 12.9 5.1 0.1 12.0 1.7 2.3 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 CCD23184.1 - 0.064 12.6 1.2 0.11 11.9 0.2 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 CCD23184.1 - 0.18 12.0 6.3 0.085 13.1 2.1 2.2 1 1 1 2 2 2 0 ABC transporter Glyco_hydro_76 PF03663.9 CCD23185.1 - 1.9e-152 507.9 25.9 2.4e-152 507.6 17.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 UQ_con PF00179.21 CCD23186.1 - 7.5e-50 168.0 0.0 8.5e-50 167.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCD23186.1 - 0.079 12.8 0.5 0.11 12.3 0.4 1.6 1 1 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 CCD23186.1 - 0.086 12.5 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 Prokaryotic E2 family B Amino_oxidase PF01593.19 CCD23187.1 - 9.2e-63 212.8 0.0 2.3e-62 211.5 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 CCD23187.1 - 6.7e-10 38.8 0.3 1.5e-09 37.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCD23187.1 - 3e-09 37.2 0.1 2.7e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCD23187.1 - 2.6e-05 23.2 2.2 0.00054 18.9 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CCD23187.1 - 3e-05 23.0 0.6 4.7e-05 22.4 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCD23187.1 - 4.1e-05 22.6 0.5 0.0016 17.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCD23187.1 - 0.0002 20.5 0.1 0.00034 19.7 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CCD23187.1 - 0.0003 19.3 1.3 0.007 14.8 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 CCD23187.1 - 0.00031 20.6 0.0 0.00086 19.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCD23187.1 - 0.00056 19.0 0.0 0.00091 18.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCD23187.1 - 0.012 16.0 1.6 0.29 11.5 0.2 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CCD23187.1 - 0.02 15.0 0.7 0.052 13.6 0.1 2.0 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 CCD23187.1 - 0.022 13.8 0.2 0.04 13.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.7 CCD23187.1 - 0.026 13.4 0.2 0.83 8.4 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 CCD23187.1 - 0.072 12.8 0.5 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding ThiF PF00899.16 CCD23187.1 - 0.13 12.1 0.1 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 ThiF family Fungal_trans PF04082.13 CCD23188.1 - 2.2e-19 69.3 14.9 2.2e-19 69.3 10.3 2.5 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD23188.1 - 8.8e-11 41.5 13.4 1.9e-10 40.4 9.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 CCD23190.1 - 5.6e-52 176.7 0.1 7.6e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BUD22 PF09073.5 CCD23191.1 - 1.5e-89 301.0 53.7 2.2e-89 300.5 37.2 1.2 1 0 0 1 1 1 1 BUD22 CTP_transf_1 PF01148.15 CCD23192.1 - 0.00011 22.0 31.9 0.00026 20.7 12.6 3.3 1 1 0 2 2 2 2 Cytidylyltransferase family CLU PF13236.1 CCD23193.1 - 3.2e-66 222.9 0.6 6.6e-66 221.9 0.4 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 CCD23193.1 - 3.4e-34 118.2 13.2 2.2e-25 89.5 0.0 4.1 4 0 0 4 4 4 2 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 CCD23193.1 - 4.4e-12 45.9 0.7 2.2e-11 43.7 0.3 2.5 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 CCD23193.1 - 3e-07 30.2 1.1 0.00028 20.7 0.0 3.3 3 1 1 4 4 4 2 Tetratricopeptide repeat DUF727 PF05303.7 CCD23193.1 - 0.00017 21.3 0.2 0.00061 19.5 0.1 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF727) PEX11 PF05648.9 CCD23193.1 - 0.26 10.5 3.6 0.25 10.5 0.2 2.3 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) CDK2AP PF09806.4 CCD23193.1 - 9.6 6.3 22.8 2.5 8.3 3.6 4.2 4 0 0 4 4 4 0 Cyclin-dependent kinase 2-associated protein Opi1 PF08618.5 CCD23194.1 - 4.9e-31 108.0 20.8 3.4e-23 82.2 12.1 3.2 1 1 1 2 2 2 2 Transcription factor Opi1 CENP-B_dimeris PF09026.5 CCD23194.1 - 0.0012 18.9 27.9 0.023 14.9 1.1 3.4 3 0 0 3 3 3 2 Centromere protein B dimerisation domain RXT2_N PF08595.6 CCD23194.1 - 0.015 15.1 5.7 0.015 15.1 3.9 3.5 2 1 1 3 3 3 0 RXT2-like, N-terminal Prothymosin PF03247.9 CCD23194.1 - 0.02 15.0 41.3 0.66 10.1 5.1 3.6 3 0 0 3 3 3 0 Prothymosin/parathymosin family Nucleoplasmin PF03066.10 CCD23194.1 - 0.34 10.4 31.7 0.63 9.5 2.1 3.4 3 0 0 3 3 3 0 Nucleoplasmin DUF775 PF05603.7 CCD23194.1 - 3.3 7.1 11.2 0.61 9.5 2.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF775) Adap_comp_sub PF00928.16 CCD23195.1 - 5.2e-63 212.6 1.8 9.8e-63 211.6 1.2 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Cnl2_NKP2 PF09447.5 CCD23195.1 - 0.027 14.1 0.6 0.24 11.0 0.0 2.6 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Zip PF02535.17 CCD23195.1 - 0.36 9.7 2.7 4.2 6.2 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Pterin_4a PF01329.14 CCD23196.1 - 8.1e-22 76.8 0.0 1e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase NifU PF01106.12 CCD23197.1 - 1.6e-24 85.4 0.0 2.8e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 CCD23197.1 - 3.2e-20 71.5 0.0 1e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal HOOK PF05622.7 CCD23197.1 - 0.019 12.8 0.1 0.025 12.4 0.1 1.1 1 0 0 1 1 1 0 HOOK protein YojJ PF10372.4 CCD23197.1 - 0.04 13.7 0.2 0.076 12.8 0.1 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus SSF PF00474.12 CCD23198.1 - 3.9e-18 65.2 31.1 8.1e-18 64.2 21.5 1.5 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2207 PF09972.4 CCD23198.1 - 0.0016 17.1 0.2 0.0016 17.1 0.1 3.4 3 1 1 4 4 4 1 Predicted membrane protein (DUF2207) Ribosomal_S10 PF00338.17 CCD23199.1 - 7.4e-27 93.0 1.0 1.2e-26 92.3 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF4075 PF13294.1 CCD23199.1 - 0.05 13.6 0.7 0.11 12.5 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) YchF-GTPase_C PF06071.8 CCD23200.1 - 2.5e-28 97.6 0.4 1.7e-27 94.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CCD23200.1 - 1.6e-14 53.8 0.8 6.5e-14 51.8 0.5 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 CCD23200.1 - 2.6e-05 23.9 0.0 6.9e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CCD23200.1 - 0.00072 18.8 0.0 0.0015 17.8 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B 2-Hacid_dh_C PF02826.14 CCD23200.1 - 0.022 13.9 0.0 6 5.9 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain OTU PF02338.14 CCD23201.1 - 1.3e-19 70.9 0.0 1.3e-19 70.9 0.0 2.0 3 0 0 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 CCD23201.1 - 2.5e-05 23.7 6.6 6.8e-05 22.3 0.0 3.0 1 1 2 3 3 3 2 Peptidase C65 Otubain DUF4661 PF15576.1 CCD23201.1 - 6.9 6.2 10.6 0.53 9.8 3.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4661) Zn_clus PF00172.13 CCD23202.1 - 3.6e-07 29.9 8.6 7.4e-07 28.9 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UDPGP PF01704.13 CCD23203.1 - 2.1e-191 635.9 0.0 2.6e-191 635.6 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MIS13 PF08202.6 CCD23204.1 - 1.3e-55 188.6 51.8 1.3e-55 188.6 35.9 3.9 2 2 0 2 2 2 1 Mis12-Mtw1 protein family WD40 PF00400.27 CCD23205.1 - 1.6e-10 40.4 9.3 0.00074 19.3 0.6 6.5 7 1 0 7 7 7 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCD23205.1 - 5.2e-06 25.8 0.0 0.0022 17.4 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Asp PF00026.18 CCD23206.1 - 7e-71 239.0 0.6 1e-70 238.5 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCD23206.1 - 0.0009 19.2 0.0 0.0036 17.2 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Pox_vIL-18BP PF05566.7 CCD23206.1 - 0.0033 17.4 0.1 0.0081 16.1 0.0 1.6 1 0 0 1 1 1 1 Orthopoxvirus interleukin 18 binding protein Asp_protease_2 PF13650.1 CCD23206.1 - 0.14 12.6 2.3 18 5.9 0.0 3.6 4 0 0 4 4 4 0 Aspartyl protease BAG PF02179.11 CCD23207.1 - 2.7e-16 59.4 3.6 4e-16 58.8 2.5 1.3 1 0 0 1 1 1 1 BAG domain SAS4 PF15460.1 CCD23207.1 - 0.0064 16.3 2.7 0.015 15.1 1.9 1.8 1 1 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 U-box PF04564.10 CCD23208.1 - 0.0017 18.2 0.2 1.3 9.0 0.0 3.0 2 0 0 2 2 2 2 U-box domain HEAT PF02985.17 CCD23208.1 - 0.004 17.0 0.1 0.045 13.8 0.0 3.0 3 0 0 3 3 3 1 HEAT repeat DUF4061 PF13270.1 CCD23208.1 - 0.0081 16.2 0.1 0.044 13.8 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4061) Zip PF02535.17 CCD23208.1 - 0.052 12.5 2.1 0.1 11.5 1.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_L2_C PF03947.13 CCD23209.1 - 2.5e-41 140.5 2.1 3.7e-41 139.9 1.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCD23209.1 - 2.8e-13 49.6 0.2 6.6e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L29e PF01779.12 CCD23210.1 - 1.5e-23 82.3 9.5 2.2e-23 81.8 6.6 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family His_biosynth PF00977.16 CCD23211.1 - 3.8e-26 91.7 0.0 5e-26 91.3 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein Chordopox_A13L PF05961.6 CCD23211.1 - 0.06 13.2 0.4 0.12 12.2 0.3 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein Tim44 PF04280.10 CCD23212.1 - 6.4e-33 113.8 0.0 1.5e-32 112.6 0.0 1.7 1 0 0 1 1 1 1 Tim44-like domain MCPVI PF02993.9 CCD23212.1 - 0.1 12.7 1.9 0.23 11.5 0.2 2.3 2 1 1 3 3 3 0 Minor capsid protein VI bZIP_1 PF00170.16 CCD23214.1 - 5.5e-07 29.4 17.4 1.4e-06 28.1 12.1 1.7 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 CCD23214.1 - 0.054 13.0 3.5 0.13 11.8 2.1 1.8 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain BEX PF04538.7 CCD23214.1 - 0.13 12.5 5.2 0.3 11.3 3.6 1.6 1 0 0 1 1 1 0 Brain expressed X-linked like family bZIP_2 PF07716.10 CCD23214.1 - 0.87 9.4 16.5 1.9 8.3 11.4 1.6 1 0 0 1 1 1 0 Basic region leucine zipper V_ATPase_I PF01496.14 CCD23214.1 - 1.6 6.5 11.1 2.4 5.8 7.7 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF763 PF05559.6 CCD23214.1 - 1.6 7.5 7.3 3.3 6.5 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF763) IATP PF04568.7 CCD23214.1 - 3 7.9 7.7 8.4 6.4 5.4 1.8 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP Form_Nir_trans PF01226.12 CCD23215.1 - 1.1e-67 227.5 16.3 1.4e-67 227.2 11.3 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter BRAP2 PF07576.7 CCD23216.1 - 8.4e-27 92.9 2.1 9.1e-27 92.8 0.3 1.9 2 0 0 2 2 2 1 BRCA1-associated protein 2 zf-UBP PF02148.14 CCD23216.1 - 6.6e-21 74.1 7.5 1.7e-20 72.9 5.2 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 CCD23216.1 - 5.8e-10 38.8 10.8 5.8e-10 38.8 7.5 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCD23216.1 - 1.1e-05 24.9 6.8 1.1e-05 24.9 4.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCD23216.1 - 1.7e-05 24.3 8.4 1.7e-05 24.3 5.8 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCD23216.1 - 2.3e-05 23.9 9.8 2.3e-05 23.9 6.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD23216.1 - 3.6e-05 23.6 10.0 3.6e-05 23.6 6.9 2.2 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCD23216.1 - 0.00034 20.6 5.0 0.00034 20.6 3.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CCD23216.1 - 0.0006 19.4 4.5 0.0033 17.1 3.2 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 CCD23216.1 - 0.0019 18.0 2.8 0.0072 16.1 1.9 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 CCD23216.1 - 0.58 10.0 6.7 3 7.8 4.7 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Flp_N PF03930.9 CCD23216.1 - 0.86 9.4 6.4 6.2 6.6 0.4 3.0 2 1 1 3 3 3 0 Recombinase Flp protein N-terminus zf-RING_4 PF14570.1 CCD23216.1 - 1.9 8.1 13.8 0.12 12.0 5.5 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Nol1_Nop2_Fmu PF01189.12 CCD23217.1 - 4.9e-91 305.0 0.0 2.6e-73 246.8 0.0 2.2 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CCD23217.1 - 0.00017 21.5 0.1 0.00059 19.8 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 CCD23217.1 - 0.0023 18.5 0.1 0.033 14.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.15 CCD23217.1 - 0.035 13.1 0.1 0.063 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CCD23217.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain zf-UBR PF02207.15 CCD23218.1 - 1.2e-11 44.1 17.3 1.2e-11 44.1 12.0 2.6 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) DUF1792 PF08759.6 CCD23218.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1792) DUF406 PF04175.7 CCD23218.1 - 0.062 13.7 4.9 0.11 12.9 1.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF406) ArfGap PF01412.13 CCD23219.1 - 2e-26 92.0 2.6 3.8e-26 91.1 1.8 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 CCD23219.1 - 0.034 14.0 0.1 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Synapsin_N PF10581.4 CCD23219.1 - 0.069 12.9 1.9 0.2 11.4 1.3 1.9 1 0 0 1 1 1 0 Synapsin N-terminal Acid_PPase PF12689.2 CCD23220.1 - 2.5e-43 147.6 0.0 2.8e-43 147.4 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase GST_C_2 PF13410.1 CCD23221.1 - 9.7e-06 25.3 0.0 1.9e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCD23221.1 - 0.011 15.7 0.0 0.062 13.2 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain EMP24_GP25L PF01105.19 CCD23223.1 - 5.5e-42 143.5 0.2 8.1e-42 142.9 0.2 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD chaperone_DMP PF10448.4 CCD23223.1 - 0.0067 16.3 0.1 0.0085 15.9 0.1 1.2 1 0 0 1 1 1 1 20S proteasome chaperone Metallophos PF00149.23 CCD23224.1 - 2.6e-44 151.0 0.1 3.2e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_6 PF13964.1 CCD23225.1 - 5.3e-15 54.8 1.4 0.00015 21.7 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 CCD23225.1 - 2.7e-13 49.2 2.9 4.2e-05 22.9 0.1 4.8 4 1 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 CCD23225.1 - 1.7e-10 40.5 1.5 0.024 14.4 0.0 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CCD23225.1 - 2e-10 40.5 3.5 0.035 14.2 0.0 6.0 4 1 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CCD23225.1 - 1.1e-08 34.5 0.0 0.0067 16.1 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CCD23225.1 - 0.0031 17.4 0.0 1.7 8.6 0.0 3.1 3 0 0 3 3 3 2 Kelch motif WD40 PF00400.27 CCD23226.1 - 2.1e-16 59.1 2.4 0.00063 19.5 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Ribosomal_S26e PF01283.14 CCD23227.1 - 4e-51 172.0 9.4 4.8e-51 171.7 6.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1101 PF06503.6 CCD23227.1 - 0.021 13.6 0.1 0.022 13.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) Fer4_7 PF12838.2 CCD23227.1 - 0.17 12.2 3.4 0.2 12.0 0.3 2.2 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 CCD23227.1 - 0.2 11.4 3.1 0.25 11.1 0.6 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4 PF00037.22 CCD23227.1 - 0.24 11.0 0.4 0.24 11.0 0.3 1.9 2 0 0 2 2 2 0 4Fe-4S binding domain zf-C2H2 PF00096.21 CCD23228.1 - 1.1e-10 41.1 21.7 1.9e-06 27.8 2.3 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD23228.1 - 1.6e-07 31.1 11.5 3.4e-05 23.8 0.8 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCD23228.1 - 1.3e-06 28.3 11.5 0.0041 17.2 0.9 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CCD23228.1 - 2.6e-05 24.3 2.7 2.6e-05 24.3 1.9 4.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-BED PF02892.10 CCD23228.1 - 0.00014 21.5 4.8 0.26 11.1 0.8 2.8 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.1 CCD23228.1 - 0.0006 19.6 1.7 0.0006 19.6 1.2 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 CCD23228.1 - 0.0012 19.0 10.1 0.2 11.9 2.0 2.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CCD23228.1 - 0.0029 17.7 2.7 0.0029 17.7 1.9 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding PyrI_C PF02748.10 CCD23228.1 - 0.025 14.0 0.7 0.24 10.8 0.1 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.2 CCD23228.1 - 0.064 13.3 8.4 1.1 9.4 0.3 3.1 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CCD23229.1 - 5.4e-06 26.4 11.1 0.00061 19.9 0.9 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 CCD23229.1 - 0.0058 16.7 0.6 0.0058 16.7 0.4 2.7 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CCD23229.1 - 0.027 14.8 0.6 0.027 14.8 0.4 3.6 4 1 0 4 4 4 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD23229.1 - 0.058 13.7 0.2 0.058 13.7 0.1 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.10 CCD23229.1 - 1.9 8.2 10.8 0.32 10.7 3.2 2.4 1 1 1 2 2 2 0 BED zinc finger eIF-6 PF01912.13 CCD23230.1 - 3.3e-85 284.1 0.4 4.2e-85 283.8 0.2 1.1 1 0 0 1 1 1 1 eIF-6 family Actin PF00022.14 CCD23231.1 - 1.7e-55 188.0 0.0 3.5e-55 187.0 0.0 1.5 1 1 0 1 1 1 1 Actin SMC_N PF02463.14 CCD23232.1 - 1.3e-72 243.6 36.8 4.4e-72 241.8 25.5 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCD23232.1 - 2.5e-23 82.3 0.2 1.2e-22 80.0 0.0 2.4 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCD23232.1 - 1.3e-05 25.2 8.1 1.3e-05 25.2 5.6 5.4 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.1 CCD23232.1 - 3.2e-05 23.3 0.0 7.3e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ERM PF00769.14 CCD23232.1 - 0.00059 19.4 19.4 0.00059 19.4 13.4 6.4 3 2 2 5 5 5 2 Ezrin/radixin/moesin family Filament PF00038.16 CCD23232.1 - 0.00061 19.3 15.4 0.00061 19.3 10.7 6.9 3 2 2 7 7 7 2 Intermediate filament protein Occludin_ELL PF07303.8 CCD23232.1 - 0.00079 20.1 3.8 0.00079 20.1 2.6 8.9 4 2 5 10 10 10 1 Occludin homology domain DUF972 PF06156.8 CCD23232.1 - 0.013 15.8 3.7 0.013 15.8 2.6 9.2 4 3 5 9 9 9 0 Protein of unknown function (DUF972) DUF3584 PF12128.3 CCD23232.1 - 0.1 9.9 83.1 0.081 10.2 16.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Aminotran_1_2 PF00155.16 CCD23234.1 - 1.5e-30 106.3 0.0 2.2e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCD23234.1 - 0.014 14.5 0.0 0.033 13.3 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Glyco_hydro_20 PF00728.17 CCD23234.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain DnaJ PF00226.26 CCD23235.1 - 3.2e-27 94.0 2.8 9.3e-27 92.5 1.3 2.1 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 CCD23235.1 - 1.9e-18 66.1 0.3 4.4e-14 52.1 0.0 3.2 3 1 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCD23235.1 - 2.3e-11 43.5 36.1 4.7e-08 32.9 9.3 2.9 1 1 2 3 3 3 3 DnaJ central domain Cytochrom_c3_2 PF14537.1 CCD23235.1 - 2e-05 24.8 0.6 2e-05 24.8 0.4 2.4 2 1 0 2 2 2 1 Cytochrome c3 Cytochrome_C7 PF14522.1 CCD23235.1 - 0.0068 16.0 3.9 0.0068 16.0 2.7 2.3 1 1 0 2 2 2 1 Cytochrome c7 zinc_ribbon_6 PF14599.1 CCD23235.1 - 0.034 13.9 0.8 0.034 13.9 0.5 2.4 3 0 0 3 3 3 0 Zinc-ribbon Cytochrome_C554 PF13435.1 CCD23235.1 - 0.056 13.4 7.4 0.15 12.1 1.2 2.7 1 1 1 2 2 2 0 Cytochrome c554 and c-prime zf-CHY PF05495.7 CCD23235.1 - 0.15 12.2 4.4 3.7 7.7 0.4 2.3 2 0 0 2 2 2 0 CHY zinc finger A2L_zn_ribbon PF08792.5 CCD23235.1 - 0.82 9.2 12.9 1.3 8.5 0.6 3.4 2 1 1 3 3 3 0 A2L zinc ribbon domain Cytochrome_CBB3 PF13442.1 CCD23235.1 - 1.5 9.0 5.9 11 6.2 0.5 2.8 1 1 1 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Stc1 PF12898.2 CCD23235.1 - 4.6 7.3 9.1 4.2 7.4 0.7 2.7 1 1 1 2 2 2 0 Stc1 domain Nsp1_C PF05064.8 CCD23236.1 - 0.015 14.9 0.1 0.015 14.9 0.1 2.4 3 0 0 3 3 3 0 Nsp1-like C-terminal region HDC PF02329.11 CCD23236.1 - 0.056 12.0 0.0 0.08 11.5 0.0 1.2 1 0 0 1 1 1 0 Histidine carboxylase PI chain Sulfate_transp PF00916.15 CCD23237.1 - 9.2e-86 287.3 2.0 9.2e-86 287.3 1.4 2.0 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CCD23237.1 - 1.4e-32 111.1 2.2 6.9e-32 108.9 1.5 2.3 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CCD23237.1 - 3.2e-06 26.5 0.0 6.2e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CCD23237.1 - 0.0032 17.4 0.2 0.0066 16.4 0.1 1.4 1 0 0 1 1 1 1 STAS domain AMPKBI PF04739.10 CCD23238.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain Nyv1_N PF09426.5 CCD23239.1 - 3.3e-57 192.0 0.8 5.9e-57 191.2 0.6 1.4 1 0 0 1 1 1 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.16 CCD23239.1 - 3.1e-26 90.8 2.8 4.3e-26 90.3 2.0 1.2 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.8 CCD23239.1 - 0.0086 15.4 0.9 0.013 14.9 0.7 1.2 1 0 0 1 1 1 1 fzo-like conserved region DUF1002 PF06207.6 CCD23239.1 - 0.12 11.6 2.6 0.18 11.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Pkinase PF00069.20 CCD23242.1 - 1.1e-72 244.3 1.0 6.7e-72 241.7 0.7 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23242.1 - 3.9e-41 140.8 0.5 3.2e-39 134.5 0.4 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 CCD23242.1 - 8.5e-20 69.9 0.1 1.8e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 CCD23242.1 - 4.3e-06 25.9 0.6 8.9e-06 24.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCD23242.1 - 0.00025 20.1 0.1 0.0005 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD23242.1 - 0.022 14.4 0.0 0.13 11.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family WaaY PF06176.6 CCD23242.1 - 0.037 13.2 0.3 0.065 12.4 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 CCD23242.1 - 0.075 12.3 1.9 0.099 11.9 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL zf-C2H2 PF00096.21 CCD23243.1 - 1.6e-08 34.4 11.9 0.00062 19.9 1.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD23243.1 - 6.1e-05 23.0 8.2 0.022 15.0 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD23243.1 - 0.00019 21.5 12.4 0.00034 20.7 0.4 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 CCD23243.1 - 0.0089 16.2 8.3 0.0089 16.2 0.8 3.2 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCD23243.1 - 0.19 11.9 5.0 0.8 9.9 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CCD23243.1 - 1.3 8.8 9.1 0.9 9.3 0.9 2.4 1 1 0 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.1 CCD23243.1 - 2.5 8.5 10.2 1.3 9.4 0.6 3.1 2 1 0 2 2 2 0 C2H2-type zinc-finger domain B12D PF06522.6 CCD23244.1 - 0.0022 17.6 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit MmgE_PrpD PF03972.9 CCD23245.1 - 3.3e-142 473.7 0.0 4e-142 473.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF2555 PF10742.4 CCD23245.1 - 0.072 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2555) Nic96 PF04097.9 CCD23246.1 - 3.1e-203 676.3 3.4 4.1e-203 675.9 2.3 1.1 1 0 0 1 1 1 1 Nup93/Nic96 PPI_Ypi1 PF07491.6 CCD23247.1 - 5e-22 77.2 6.7 1.5e-21 75.7 4.7 1.8 1 1 0 1 1 1 1 Protein phosphatase inhibitor CDC45 PF02724.9 CCD23247.1 - 0.028 12.4 7.3 0.035 12.1 5.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.8 CCD23247.1 - 0.037 13.3 6.0 0.044 13.1 4.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SR-25 PF10500.4 CCD23247.1 - 0.047 13.1 16.4 0.069 12.6 11.4 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein JAB PF01398.16 CCD23248.1 - 4.7e-35 119.7 1.3 5.7e-35 119.4 0.1 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CCD23248.1 - 5.4e-23 81.2 3.9 1.2e-22 80.1 2.7 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CCD23248.1 - 1.2e-08 34.4 0.0 2.5e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UCH PF00443.24 CCD23249.1 - 2.8e-08 33.1 1.9 6.2e-08 32.0 1.3 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCD23249.1 - 6.1e-06 26.2 0.4 6.1e-06 26.2 0.3 1.8 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein MtrA PF04208.9 CCD23249.1 - 0.16 11.4 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit A Peptidase_M24 PF00557.19 CCD23250.1 - 2.7e-53 180.6 0.0 3.5e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CCD23250.1 - 1e-25 89.7 0.0 2.7e-25 88.3 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain WHG PF13305.1 CCD23250.1 - 0.033 14.7 0.0 0.09 13.3 0.0 1.7 1 0 0 1 1 1 0 WHG domain Citrate_synt PF00285.16 CCD23251.1 - 1.5e-88 296.9 0.0 1.8e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Hat1_N PF10394.4 CCD23253.1 - 1.1e-35 123.0 4.4 2.8e-35 121.7 3.1 1.7 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.19 CCD23253.1 - 0.0012 18.8 0.0 0.0036 17.3 0.0 1.8 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCD23253.1 - 0.0036 17.4 0.0 0.0085 16.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCD23253.1 - 0.016 15.3 0.0 0.03 14.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EAP30 PF04157.11 CCD23254.1 - 2.1e-48 164.4 0.0 2.3e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family PseudoU_synth_1 PF01416.15 CCD23255.1 - 2e-28 98.9 0.0 1.3e-18 67.3 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase Sulfate_transp PF00916.15 CCD23256.1 - 1e-60 205.1 8.1 2.2e-60 204.0 5.6 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CCD23256.1 - 5e-28 96.6 4.1 5e-28 96.6 2.9 2.0 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CCD23256.1 - 5.3e-19 67.7 0.0 1.1e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CCD23256.1 - 0.0031 17.5 0.0 0.012 15.6 0.0 1.9 1 1 0 1 1 1 1 STAS domain ETF PF01012.16 CCD23257.1 - 1.5e-32 112.6 0.0 2.9e-32 111.6 0.0 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 CCD23257.1 - 3.2e-32 109.9 0.1 6.5e-32 108.9 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain PolyA_pol PF01743.15 CCD23259.1 - 2.4e-29 102.0 0.0 5.8e-29 100.8 0.0 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CCD23259.1 - 4.8e-06 26.0 0.0 1.1e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 CCD23259.1 - 0.016 15.0 3.1 0.12 12.2 2.2 2.3 1 1 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative JmjC PF02373.17 CCD23260.1 - 7.5e-41 138.9 1.7 7.5e-41 138.9 1.2 3.2 3 0 0 3 3 3 1 JmjC domain, hydroxylase JmjN PF02375.12 CCD23260.1 - 1.2e-14 53.5 3.1 3.1e-14 52.1 2.1 1.8 1 0 0 1 1 1 1 jmjN domain zf-H2C2_2 PF13465.1 CCD23260.1 - 2e-07 30.9 10.7 8.7e-07 28.9 5.0 2.7 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCD23260.1 - 2.7e-06 27.3 16.5 0.0022 18.2 2.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD23260.1 - 2.7e-05 24.1 12.3 0.0018 18.4 0.9 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCD23260.1 - 0.061 13.2 9.0 0.11 12.4 2.2 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 CCD23260.1 - 0.52 10.3 4.8 2.3 8.2 3.4 2.0 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 CCD23260.1 - 0.63 10.2 10.6 0.26 11.5 2.3 2.7 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding ADK PF00406.17 CCD23261.1 - 4.9e-42 143.3 0.0 6.2e-42 143.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CCD23261.1 - 8.5e-15 54.1 1.8 1.2e-14 53.6 0.1 2.0 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.1 CCD23261.1 - 2.4e-06 27.8 0.0 4.7e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCD23261.1 - 1.6e-05 25.6 0.0 2.6e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCD23261.1 - 0.00011 22.1 0.0 0.0005 19.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCD23261.1 - 0.0041 16.3 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CCD23261.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase DUF1227 PF06777.6 CCD23262.1 - 1.5e-58 196.6 2.5 2e-58 196.2 0.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 CCD23262.1 - 6.2e-51 172.2 4.3 1.2e-50 171.3 3.0 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CCD23262.1 - 1.7e-45 154.9 0.0 6.4e-45 153.0 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 CCD23262.1 - 0.0032 16.9 0.2 0.89 9.0 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase SNF2_N PF00176.18 CCD23262.1 - 0.011 14.5 0.1 0.34 9.6 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain ResIII PF04851.10 CCD23262.1 - 0.04 13.7 0.1 3.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sec63 PF02889.11 CCD23263.1 - 1.3e-164 546.8 10.7 2.6e-89 299.5 0.1 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CCD23263.1 - 5.5e-37 126.8 0.0 4.1e-31 107.7 0.0 2.9 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CCD23263.1 - 8.2e-09 35.5 0.0 8.2e-09 35.5 0.0 3.8 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCD23263.1 - 4.1e-08 32.9 0.0 3.1e-07 30.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCD23263.1 - 0.0011 19.0 0.0 0.0071 16.4 0.0 2.4 1 0 0 1 1 1 1 AAA domain Kelch_1 PF01344.20 CCD23263.1 - 0.1 12.1 0.0 3.8 7.1 0.0 2.8 2 0 0 2 2 2 0 Kelch motif Rad17 PF03215.10 CCD23264.1 - 3.4e-85 286.7 8.3 1.8e-83 281.0 5.7 2.2 1 1 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CCD23264.1 - 1.2e-05 25.3 0.0 4e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CCD23264.1 - 0.00062 20.5 0.0 0.00062 20.5 0.0 3.5 2 1 0 2 2 1 1 AAA domain AAA PF00004.24 CCD23264.1 - 0.0024 18.0 0.0 0.0075 16.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCD23264.1 - 0.0028 17.7 0.8 0.01 15.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCD23264.1 - 0.003 17.0 0.1 0.019 14.4 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CCD23264.1 - 0.0044 17.3 0.5 0.023 14.9 0.0 2.4 2 0 0 2 2 2 1 ABC transporter Mg_chelatase PF01078.16 CCD23264.1 - 0.024 13.7 0.0 0.044 12.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CCD23264.1 - 0.027 14.6 0.5 0.23 11.6 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 CCD23264.1 - 0.037 13.7 0.0 0.091 12.4 0.0 1.6 1 0 0 1 1 1 0 NTPase MobB PF03205.9 CCD23264.1 - 0.086 12.5 0.1 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CCD23264.1 - 0.096 12.5 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCD23264.1 - 0.099 11.8 0.6 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCD23264.1 - 0.13 12.5 0.0 0.13 12.5 0.0 4.4 2 1 0 3 3 3 0 AAA domain Glutaredoxin PF00462.19 CCD23265.1 - 1.3e-15 57.1 0.0 2e-14 53.2 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 CCD23265.1 - 2.8e-13 49.4 0.0 6.6e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 CCD23265.1 - 5.6e-06 26.0 0.0 2.7e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.1 CCD23265.1 - 0.0031 17.7 0.1 0.33 11.1 0.0 3.3 2 2 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCD23265.1 - 0.017 15.2 7.0 0.057 13.5 0.0 3.4 3 2 1 4 4 4 0 Thioredoxin-like Period_C PF12114.3 CCD23265.1 - 0.07 12.7 0.8 0.099 12.2 0.6 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region GnHR_trans PF12369.3 CCD23265.1 - 5.2 7.5 7.9 6.1 7.3 4.5 1.8 1 1 1 2 2 2 0 Gonadotropin hormone receptor transmembrane region Methyltransf_31 PF13847.1 CCD23266.1 - 5.1e-09 35.8 0.1 1.1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCD23266.1 - 6.5e-09 36.1 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCD23266.1 - 3.9e-08 33.6 0.0 3.9e-08 33.6 0.0 2.1 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD23266.1 - 1.3e-07 31.9 0.8 6.7e-07 29.6 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD23266.1 - 6.9e-07 29.8 0.1 1.7e-06 28.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCD23266.1 - 0.00021 21.0 0.2 0.00034 20.3 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCD23266.1 - 0.0003 19.9 0.1 0.00047 19.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CENP-B_dimeris PF09026.5 CCD23266.1 - 0.0013 18.9 2.0 0.0028 17.8 1.4 1.6 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Methyltransf_26 PF13659.1 CCD23266.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCD23266.1 - 0.012 14.9 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 CCD23266.1 - 0.014 14.8 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 CCD23266.1 - 0.056 12.4 0.0 0.096 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Nucleoplasmin PF03066.10 CCD23266.1 - 1.4 8.3 9.2 2.5 7.6 6.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 CCD23266.1 - 1.7 8.8 6.6 3.5 7.8 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 CCD23266.1 - 6.7 6.5 6.6 14 5.4 4.6 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal PBP1_TM PF14812.1 CCD23266.1 - 9.8 6.5 12.6 19 5.6 8.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_12 PF13087.1 CCD23267.1 - 3.4e-59 199.5 0.2 3.4e-59 199.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CCD23267.1 - 1.2e-45 155.9 0.4 1.2e-45 155.9 0.3 3.2 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 CCD23267.1 - 8.9e-11 41.3 0.0 2.9e-10 39.7 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CCD23267.1 - 4.5e-10 39.4 0.0 4.4e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CCD23267.1 - 2e-07 30.7 2.3 0.13 11.7 0.0 4.0 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 CCD23267.1 - 0.0028 16.8 0.0 0.021 14.0 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein UvrD_C_2 PF13538.1 CCD23267.1 - 0.0032 17.5 0.0 0.0095 16.0 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Arch_ATPase PF01637.13 CCD23267.1 - 0.0038 16.9 2.7 0.01 15.5 0.0 2.8 3 1 0 3 3 3 1 Archaeal ATPase AAA_22 PF13401.1 CCD23267.1 - 0.0041 17.2 0.0 0.016 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CCD23267.1 - 0.0097 16.1 0.0 0.039 14.1 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCD23267.1 - 0.016 15.2 0.0 0.038 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain 14-3-3 PF00244.15 CCD23268.1 - 8.6e-115 381.7 4.9 8.6e-115 381.7 3.4 1.4 1 1 0 1 1 1 1 14-3-3 protein DUF885 PF05960.6 CCD23268.1 - 0.04 13.0 7.7 0.24 10.5 5.4 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) HisKA PF00512.20 CCD23268.1 - 5.7 7.0 6.9 1.4 8.9 0.0 3.0 3 0 0 3 3 3 0 His Kinase A (phospho-acceptor) domain E1_dh PF00676.15 CCD23269.1 - 1.7e-120 401.2 0.0 2.7e-120 400.6 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CCD23269.1 - 0.0015 17.5 0.0 0.0033 16.4 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase YhjQ PF06564.7 CCD23269.1 - 0.027 13.8 0.2 0.051 12.9 0.2 1.4 1 0 0 1 1 1 0 YhjQ protein Tho2 PF11262.3 CCD23269.1 - 0.043 12.8 2.4 0.07 12.1 1.7 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 KRTAP7 PF15034.1 CCD23269.1 - 0.043 14.4 3.9 0.14 12.8 0.1 3.0 2 1 0 2 2 2 0 KRTAP type 7 family Folate_carrier PF01770.13 CCD23269.1 - 0.64 8.4 2.0 1 7.7 1.4 1.2 1 0 0 1 1 1 0 Reduced folate carrier Rad51 PF08423.6 CCD23270.1 - 1.4e-123 410.8 0.1 1.8e-123 410.4 0.0 1.2 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CCD23270.1 - 5.9e-10 38.8 0.0 8.4e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CCD23270.1 - 5.2e-09 35.5 0.0 9.3e-09 34.7 0.0 1.5 1 1 0 1 1 1 1 KaiC RecA PF00154.16 CCD23270.1 - 5.8e-09 35.4 0.1 7.9e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein PAXNEB PF05625.6 CCD23270.1 - 0.058 12.2 0.0 0.26 10.0 0.0 1.8 2 0 0 2 2 2 0 PAXNEB protein EMP70 PF02990.11 CCD23272.1 - 8.5e-210 697.6 11.7 1.3e-209 697.0 8.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 SUN PF03856.8 CCD23272.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Beta-glucosidase (SUN family) Rax2 PF12768.2 CCD23273.1 - 2.5e-56 190.9 3.5 2.5e-56 190.9 2.4 6.1 4 2 1 6 6 6 3 Cortical protein marker for cell polarity PWI PF01480.12 CCD23274.1 - 0.01 15.9 1.9 0.03 14.4 0.4 2.5 2 0 0 2 2 2 0 PWI domain POX PF07526.6 CCD23274.1 - 1.3 9.2 10.6 0.22 11.7 2.2 2.7 2 0 0 2 2 2 0 Associated with HOX Mss4 PF04421.8 CCD23275.1 - 2.8e-20 71.9 3.5 1.6e-14 53.4 0.4 2.1 1 1 1 2 2 2 2 Mss4 protein DEAD PF00270.24 CCD23276.1 - 3.4e-43 147.0 1.2 3.8e-42 143.6 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD23276.1 - 2.8e-25 87.9 0.6 7.3e-25 86.6 0.1 2.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD23276.1 - 0.00017 21.4 0.1 0.00017 21.4 0.1 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCD23276.1 - 0.031 14.4 0.3 0.15 12.2 0.2 2.1 1 1 0 1 1 1 0 AAA domain DUF4137 PF13593.1 CCD23276.1 - 0.27 10.2 0.0 0.42 9.6 0.0 1.1 1 0 0 1 1 1 0 SBF-like CPA transporter family (DUF4137) Mito_carr PF00153.22 CCD23277.1 - 1.1e-70 233.3 0.3 3e-25 87.7 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 CCD23278.1 - 2.5e-27 95.6 0.0 2.5e-27 95.6 0.0 2.5 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23278.1 - 4.4e-09 35.7 0.0 1.2e-08 34.3 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCD23278.1 - 0.082 12.6 0.0 3.2 7.4 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Iron_permease PF04120.7 CCD23280.1 - 2.6e-24 85.2 28.3 1.7e-15 56.7 0.5 5.7 6 0 0 6 6 6 5 Low affinity iron permease FtsQ PF03799.10 CCD23280.1 - 0.15 12.2 0.0 20 5.3 0.0 2.4 2 0 0 2 2 2 0 Cell division protein FtsQ HECT PF00632.20 CCD23281.1 - 1.6e-90 303.4 0.0 2.3e-90 302.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CCD23281.1 - 6e-34 115.5 19.7 7e-11 41.7 1.0 3.8 3 0 0 3 3 3 3 WW domain C2 PF00168.25 CCD23281.1 - 2.8e-16 59.1 0.4 1.3e-15 56.9 0.2 2.2 2 0 0 2 2 2 1 C2 domain TRH PF05438.7 CCD23281.1 - 0.023 14.0 0.2 0.042 13.2 0.1 1.4 1 0 0 1 1 1 0 Thyrotropin-releasing hormone (TRH) Ribosomal_S8e PF01201.17 CCD23282.1 - 5.3e-40 136.6 6.9 1.2e-39 135.4 4.8 1.6 1 1 0 1 1 1 1 Ribosomal protein S8e YebF PF13995.1 CCD23282.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 YebF-like protein HPD PF05044.7 CCD23282.1 - 0.092 12.4 1.0 0.1 12.2 0.1 1.5 2 0 0 2 2 2 0 Homeo-prospero domain Sas10_Utp3 PF04000.10 CCD23283.1 - 7.7e-11 42.0 2.6 3e-10 40.1 1.8 2.1 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Phlebovirus_G1 PF07243.6 CCD23283.1 - 0.13 10.3 1.3 0.22 9.6 0.9 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 FERM_M PF00373.13 CCD23283.1 - 5.5 7.1 7.6 0.69 10.0 2.1 2.2 2 1 0 2 2 2 0 FERM central domain Vfa1 PF08432.5 CCD23284.1 - 9.5e-42 143.0 5.8 1.1e-41 142.8 4.0 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.1 CCD23284.1 - 0.078 11.9 3.3 3.8 6.3 2.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF4390 PF14334.1 CCD23284.1 - 0.13 11.4 1.8 0.19 10.8 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4390) DUF4239 PF14023.1 CCD23284.1 - 0.14 11.4 3.2 0.065 12.5 0.8 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DDHD PF02862.12 CCD23284.1 - 1.1 8.9 5.1 1.5 8.5 3.5 1.1 1 0 0 1 1 1 0 DDHD domain DUF334 PF03904.8 CCD23284.1 - 3.1 7.0 7.2 5 6.3 5.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Pkinase PF00069.20 CCD23285.1 - 8.3e-56 189.0 0.4 1.1e-36 126.3 0.9 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23285.1 - 5.7e-26 91.1 0.4 4.6e-23 81.6 0.2 3.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD23285.1 - 1e-06 27.9 0.0 0.00041 19.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like SR-25 PF10500.4 CCD23285.1 - 0.016 14.6 0.2 0.016 14.6 0.1 6.0 7 1 1 8 8 8 0 Nuclear RNA-splicing-associated protein APH PF01636.18 CCD23285.1 - 0.031 14.0 0.0 0.5 10.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family F-box-like PF12937.2 CCD23286.1 - 4.2e-06 26.3 0.2 7.7e-06 25.5 0.2 1.4 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.1 CCD23286.1 - 0.00093 18.7 0.2 0.0025 17.3 0.0 1.8 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 CCD23286.1 - 0.0024 17.4 0.2 0.0087 15.6 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat F-box PF00646.28 CCD23286.1 - 0.0036 16.9 1.0 0.0086 15.7 0.7 1.5 1 0 0 1 1 1 1 F-box domain TPR_8 PF13181.1 CCD23286.1 - 0.0038 16.9 0.3 0.026 14.2 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCD23286.1 - 0.018 14.8 0.1 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 CCD23286.1 - 0.019 14.8 0.2 0.049 13.5 0.1 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.1 CCD23286.1 - 0.044 13.7 0.1 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCD23286.1 - 0.063 13.0 0.1 0.46 10.3 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Fungal_trans PF04082.13 CCD23287.1 - 7.1e-37 126.6 7.0 1.8e-36 125.3 4.8 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD23287.1 - 4.1e-10 39.3 8.6 7.2e-10 38.6 6.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2095 PF09868.4 CCD23288.1 - 0.069 12.9 0.5 0.084 12.6 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) EPSP_synthase PF00275.15 CCD23289.1 - 1.8e-131 438.4 0.1 2.7e-131 437.8 0.1 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CCD23289.1 - 5e-99 330.4 0.0 8.3e-99 329.7 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CCD23289.1 - 1.2e-64 218.0 0.0 1.9e-64 217.3 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 CCD23289.1 - 3.8e-37 127.5 0.0 7.6e-36 123.3 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 CCD23289.1 - 5.6e-20 71.1 0.0 1.6e-19 69.6 0.0 1.9 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CCD23289.1 - 3.7e-16 59.4 0.0 1e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 CCD23289.1 - 1.2e-07 31.2 0.0 2.5e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 CCD23289.1 - 1.8e-06 28.7 0.0 5.8e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCD23289.1 - 0.0026 17.6 0.0 0.085 12.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CCD23289.1 - 0.009 15.9 0.0 0.042 13.7 0.0 2.2 2 0 0 2 2 1 1 AAA domain CoA_binding PF02629.14 CCD23289.1 - 0.015 15.8 0.1 0.047 14.2 0.0 1.9 1 0 0 1 1 1 0 CoA binding domain 6PF2K PF01591.13 CCD23289.1 - 0.036 13.1 0.1 0.087 11.8 0.0 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase adh_short PF00106.20 CCD23290.1 - 0.00018 21.4 0.0 0.061 13.2 0.0 2.2 1 1 1 2 2 2 2 short chain dehydrogenase CH PF00307.26 CCD23291.1 - 9.1e-73 241.2 1.3 1.5e-19 70.0 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CCD23291.1 - 2.6e-07 30.1 0.1 0.031 13.9 0.0 3.8 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.1 CCD23291.1 - 1.8e-05 24.7 0.8 0.00019 21.4 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair BMF PF15185.1 CCD23291.1 - 0.0076 15.5 0.0 0.77 9.0 0.0 2.2 2 0 0 2 2 2 2 Bcl-2-modifying factor, apoptosis EF-hand_1 PF00036.27 CCD23291.1 - 0.033 13.4 0.1 13 5.3 0.0 3.5 3 0 0 3 3 3 0 EF hand Apc9 PF12856.2 CCD23292.1 - 1.8e-13 50.4 0.9 1.8e-13 50.4 0.6 2.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 9 CDC45 PF02724.9 CCD23293.1 - 1.1e-214 714.0 4.4 1.3e-214 713.8 3.1 1.0 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 CCD23293.1 - 0.0028 15.6 19.1 0.004 15.1 13.3 1.1 1 0 0 1 1 1 1 Nop14-like family Nop53 PF07767.6 CCD23293.1 - 0.019 13.9 14.4 0.029 13.3 10.0 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SprA-related PF12118.3 CCD23293.1 - 0.27 10.5 6.6 0.39 9.9 4.5 1.1 1 0 0 1 1 1 0 SprA-related family Daxx PF03344.10 CCD23293.1 - 0.33 9.3 18.2 0.56 8.6 12.6 1.3 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 CCD23293.1 - 0.59 9.3 19.2 0.94 8.6 13.3 1.3 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 CCD23293.1 - 1.2 8.4 17.1 1.4 8.2 10.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Merozoite_SPAM PF07133.6 CCD23293.1 - 1.3 8.8 33.4 0.08 12.8 16.9 2.3 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) YL1 PF05764.8 CCD23293.1 - 1.6 8.2 21.2 2.6 7.5 14.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein BUD22 PF09073.5 CCD23293.1 - 2.2 7.2 22.7 3.6 6.5 15.8 1.2 1 0 0 1 1 1 0 BUD22 TRAP_alpha PF03896.11 CCD23293.1 - 3.1 6.7 14.3 6.9 5.5 9.2 2.0 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Sdh5 PF03937.11 CCD23294.1 - 2.1e-23 81.7 0.6 3.6e-23 81.0 0.4 1.4 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Poxvirus_B22R_N PF13169.1 CCD23294.1 - 0.61 10.3 3.1 0.56 10.4 0.1 2.2 3 0 0 3 3 3 0 Poxvirus B22R protein N-terminal PCI PF01399.22 CCD23295.1 - 1.4e-06 28.5 0.0 5.1e-06 26.7 0.0 2.0 1 1 0 1 1 1 1 PCI domain Smg4_UPF3 PF03467.10 CCD23296.1 - 8.4e-19 68.2 5.4 8.4e-19 68.2 3.8 3.3 1 1 0 2 2 2 1 Smg-4/UPF3 family Dsh_C PF12316.3 CCD23296.1 - 0.69 9.9 21.0 0.65 10.0 5.2 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal LSM PF01423.17 CCD23297.1 - 5.7e-19 67.4 0.1 1e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCD23297.1 - 0.0017 18.2 0.1 0.0028 17.5 0.1 1.6 1 1 0 1 1 1 1 Ataxin 2 SM domain Pilin PF00114.14 CCD23297.1 - 0.27 11.9 2.6 0.37 11.5 0.3 2.0 1 1 1 2 2 2 0 Pilin (bacterial filament) E1-E2_ATPase PF00122.15 CCD23300.1 - 6.9e-63 211.7 7.6 6.9e-63 211.7 5.3 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCD23300.1 - 3.6e-23 83.0 0.0 8.6e-23 81.8 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCD23300.1 - 7.6e-15 55.5 0.2 5.6e-14 52.7 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCD23300.1 - 1.9e-10 40.0 0.0 1.9e-10 40.0 0.0 2.3 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 CCD23300.1 - 0.0014 18.5 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCD23300.1 - 0.0029 17.2 0.1 0.0029 17.2 0.1 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase UreE_N PF02814.10 CCD23300.1 - 0.097 12.1 0.0 3.9 7.0 0.0 2.6 2 0 0 2 2 2 0 UreE urease accessory protein, N-terminal domain Transp_cyt_pur PF02133.10 CCD23301.1 - 3.4e-16 58.8 29.4 3.8e-16 58.6 17.8 2.0 2 0 0 2 2 2 2 Permease for cytosine/purines, uracil, thiamine, allantoin COX5B PF01215.14 CCD23302.1 - 1.3e-54 183.5 0.0 1.6e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb WD40 PF00400.27 CCD23303.1 - 1.5e-17 62.6 2.1 0.0015 18.3 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Adaptin_binding PF10199.4 CCD23303.1 - 2.1 8.6 10.9 6.1 7.1 7.5 1.8 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 COX6A PF02046.10 CCD23304.1 - 1.1e-39 134.9 0.7 1.2e-39 134.7 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa MT-A70 PF05063.9 CCD23305.1 - 2.8e-55 186.5 0.2 5.4e-55 185.6 0.1 1.5 1 0 0 1 1 1 1 MT-A70 Med31 PF05669.7 CCD23305.1 - 0.059 13.1 0.1 0.059 13.1 0.1 1.9 2 0 0 2 2 2 0 SOH1 Hist_deacetyl PF00850.14 CCD23306.1 - 1.4e-80 270.8 0.0 1.8e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF3554 PF12074.3 CCD23307.1 - 1.2e-42 146.6 21.5 3e-26 92.6 0.1 6.7 5 2 2 7 7 7 2 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 CCD23307.1 - 1.1e-40 137.8 16.8 5.5e-09 36.1 0.0 13.4 11 3 5 16 16 16 9 HEAT repeats HEAT PF02985.17 CCD23307.1 - 8.8e-32 106.3 23.9 0.0044 16.9 0.0 19.1 23 0 0 23 23 23 9 HEAT repeat HEAT_EZ PF13513.1 CCD23307.1 - 1.8e-28 98.2 25.0 0.014 15.8 0.1 17.4 11 4 10 21 21 21 8 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CCD23307.1 - 7.7e-14 51.8 2.4 0.055 13.8 0.0 9.3 10 1 0 10 10 10 3 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 CCD23307.1 - 2.6e-05 24.1 0.0 1.1 9.2 0.0 6.4 5 0 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation MCR_alpha_N PF02745.10 CCD23307.1 - 0.65 9.1 3.5 1.7 7.7 1.2 2.5 3 0 0 3 3 3 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain HEAT_PBS PF03130.11 CCD23307.1 - 6.3 7.5 6.8 1e+02 3.7 0.1 5.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat D-ser_dehydrat PF14031.1 CCD23308.1 - 9.9e-18 64.1 0.0 2.5e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 CCD23308.1 - 7.3e-08 32.2 0.0 1.1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Kelch_6 PF13964.1 CCD23309.1 - 5.3e-13 48.5 3.0 2.3e-05 24.3 0.0 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CCD23309.1 - 3.2e-10 39.6 6.0 0.027 14.2 0.0 5.1 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_3 PF13415.1 CCD23309.1 - 3.3e-09 36.6 3.2 0.011 15.9 0.0 5.7 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.20 CCD23309.1 - 9.8e-09 34.6 3.5 0.00043 19.7 0.0 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.10 CCD23309.1 - 2.5e-06 27.0 0.5 0.00092 18.8 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CCD23309.1 - 4.5e-05 23.2 0.7 0.049 13.5 0.0 3.8 4 0 0 4 4 4 1 Kelch motif Yip1 PF04893.12 CCD23310.1 - 8.8e-11 41.6 4.5 1.3e-10 41.1 3.1 1.2 1 0 0 1 1 1 1 Yip1 domain DUF3337 PF11816.3 CCD23311.1 - 4.3e-60 203.8 3.5 4.3e-60 203.8 2.4 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 CCD23311.1 - 1.4e-12 46.9 7.9 0.072 13.0 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat CENP-S PF15630.1 CCD23312.1 - 2e-24 85.5 0.0 2.5e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S TFIID-31kDa PF02291.10 CCD23312.1 - 0.00036 20.3 0.0 0.00041 20.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 CCD23312.1 - 0.00082 18.7 0.0 0.00091 18.5 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Histone PF00125.19 CCD23312.1 - 0.0075 16.3 0.0 0.0097 16.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 CCD23312.1 - 0.033 13.9 0.0 0.047 13.4 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated ADH_zinc_N PF00107.21 CCD23313.1 - 0.028 13.9 0.2 0.11 12.1 0.1 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF221 PF02714.10 CCD23314.1 - 8.9e-105 350.1 14.6 8.9e-105 350.1 10.1 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCD23314.1 - 9.6e-41 138.9 4.3 1.1e-39 135.5 2.3 2.9 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CCD23314.1 - 3.8e-28 97.1 0.6 3.8e-28 97.1 0.4 1.9 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 CCD23314.1 - 4.6e-15 55.8 0.2 1e-14 54.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) BatA PF07584.6 CCD23314.1 - 0.38 10.9 0.0 0.38 10.9 0.0 3.9 5 0 0 5 5 5 0 Aerotolerance regulator N-terminal ATG19_autophagy PF12744.2 CCD23315.1 - 5.6e-13 48.6 0.3 1.4e-12 47.3 0.2 1.6 1 0 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding RasGAP PF00616.14 CCD23317.1 - 5.1e-35 120.9 1.1 3.8e-34 118.0 0.4 3.0 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RNase_T PF00929.19 CCD23318.1 - 6.4e-30 104.5 0.2 1.3e-29 103.5 0.0 1.6 2 0 0 2 2 2 1 Exonuclease SIN1 PF05422.7 CCD23319.1 - 1.1e-25 90.2 4.3 4.2e-15 55.2 0.1 3.4 3 1 0 3 3 3 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 CCD23319.1 - 0.0012 18.7 0.5 0.0044 16.8 0.1 2.2 2 0 0 2 2 2 1 GLUT4 regulating protein TUG RBD PF02196.10 CCD23319.1 - 0.12 12.1 0.0 0.39 10.5 0.0 1.8 1 0 0 1 1 1 0 Raf-like Ras-binding domain DUF2611 PF11022.3 CCD23320.1 - 1.5e-21 76.2 0.1 1.6e-21 76.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Brix PF04427.13 CCD23321.1 - 3e-39 134.6 0.3 3.8e-39 134.3 0.2 1.1 1 0 0 1 1 1 1 Brix domain DUF468 PF04318.7 CCD23321.1 - 0.02 15.4 0.0 0.062 13.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF468) ABC_tran PF00005.22 CCD23322.1 - 2.6e-52 176.7 1.0 2.5e-25 89.3 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 CCD23322.1 - 4.7e-40 137.0 24.6 2e-26 92.4 6.7 2.5 3 0 0 3 3 2 2 ABC-2 type transporter AAA_21 PF13304.1 CCD23322.1 - 5.2e-13 49.6 16.9 1.7e-07 31.5 3.7 5.1 4 1 0 4 4 4 2 AAA domain DUF258 PF03193.11 CCD23322.1 - 1.2e-09 37.5 1.2 0.00012 21.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCD23322.1 - 3e-09 37.1 0.0 0.00088 19.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CCD23322.1 - 4e-08 34.1 0.1 0.017 15.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 CCD23322.1 - 8.9e-08 31.7 0.0 0.0038 16.6 0.0 4.0 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 CCD23322.1 - 2.4e-07 31.1 2.7 0.021 15.1 0.1 3.5 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 CCD23322.1 - 2.4e-06 27.2 0.1 0.014 15.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain T2SE PF00437.15 CCD23322.1 - 3.8e-06 26.0 0.6 0.027 13.3 0.1 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.14 CCD23322.1 - 5.5e-06 25.7 12.0 5e-05 22.6 0.3 3.9 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CCD23322.1 - 6.5e-06 26.3 1.6 0.11 12.5 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCD23322.1 - 9.4e-06 25.0 8.0 0.0093 15.4 0.1 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CCD23322.1 - 3e-05 23.9 0.1 0.093 12.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.14 CCD23322.1 - 4.3e-05 23.0 0.6 0.061 12.7 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 CCD23322.1 - 5.4e-05 23.2 0.1 0.038 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 CCD23322.1 - 5.9e-05 22.2 17.4 0.0083 15.2 0.2 5.1 3 1 2 5 5 4 2 AAA ATPase domain AAA_19 PF13245.1 CCD23322.1 - 6.5e-05 22.6 0.4 0.071 12.8 0.2 2.7 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 CCD23322.1 - 8.8e-05 22.6 0.2 0.68 10.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 CCD23322.1 - 0.00024 20.8 3.4 0.055 13.1 0.0 3.2 3 0 0 3 3 3 1 Archaeal ATPase SbcCD_C PF13558.1 CCD23322.1 - 0.00029 20.7 0.4 1 9.3 0.0 3.3 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 CCD23322.1 - 0.0003 20.3 1.2 0.023 14.1 0.1 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_5 PF07728.9 CCD23322.1 - 0.00077 19.2 0.1 0.45 10.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Rad17 PF03215.10 CCD23322.1 - 0.00083 18.1 0.2 0.068 11.8 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 CCD23322.1 - 0.00092 19.1 0.0 1.1 9.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCD23322.1 - 0.0011 18.9 0.1 1.6 8.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 CCD23322.1 - 0.0016 18.1 2.4 1.4 8.6 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 CCD23322.1 - 0.0019 17.1 1.0 0.36 9.6 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain KAP_NTPase PF07693.9 CCD23322.1 - 0.0021 17.1 0.1 0.84 8.5 0.0 2.5 2 0 0 2 2 2 1 KAP family P-loop domain AAA_30 PF13604.1 CCD23322.1 - 0.0035 16.9 0.7 2.6 7.5 0.2 2.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CCD23322.1 - 0.004 16.8 2.4 4 7.1 0.0 3.2 3 0 0 3 3 3 0 NTPase AAA_10 PF12846.2 CCD23322.1 - 0.0048 16.3 9.4 0.082 12.3 0.2 2.7 3 0 0 3 3 3 2 AAA-like domain Pox_A32 PF04665.7 CCD23322.1 - 0.0053 16.0 0.2 0.14 11.4 0.0 2.5 2 0 0 2 2 2 1 Poxvirus A32 protein AAA PF00004.24 CCD23322.1 - 0.011 15.9 1.7 7.3 6.7 0.0 3.7 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.10 CCD23322.1 - 0.013 14.1 0.4 0.038 12.6 0.0 1.8 2 0 0 2 2 2 0 Adenovirus IVa2 protein PRK PF00485.13 CCD23322.1 - 0.013 15.0 0.2 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Miro PF08477.8 CCD23322.1 - 0.015 15.7 0.4 5.3 7.5 0.0 2.9 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 CCD23322.1 - 0.02 15.2 0.2 0.02 15.2 0.2 3.7 3 1 1 4 4 2 0 AAA domain UPF0079 PF02367.12 CCD23322.1 - 0.024 14.2 0.8 0.86 9.2 0.2 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ABC_ATPase PF09818.4 CCD23322.1 - 0.042 12.4 0.4 2.4 6.6 0.1 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class ATP_bind_1 PF03029.12 CCD23322.1 - 0.095 12.2 3.3 7 6.1 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 CCD23322.1 - 0.11 12.0 1.7 11 5.5 0.3 2.6 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.15 CCD23322.1 - 0.18 11.4 1.1 3.7 7.1 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase KaiC PF06745.8 CCD23322.1 - 0.19 10.8 3.2 1 8.4 0.0 3.5 5 0 0 5 5 4 0 KaiC PduV-EutP PF10662.4 CCD23322.1 - 1 8.8 4.7 3.7 7.0 0.1 2.7 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CCD23322.1 - 1.4 8.0 7.6 3.2 6.9 0.0 3.1 4 0 0 4 4 3 0 Signal recognition particle receptor beta subunit Septin PF00735.13 CCD23322.1 - 5.3 5.9 8.1 7.7 5.4 0.1 3.1 3 0 0 3 3 3 0 Septin Dynamin_N PF00350.18 CCD23322.1 - 5.8 6.7 8.6 10 5.9 0.2 3.2 3 0 0 3 3 3 0 Dynamin family DUF87 PF01935.12 CCD23322.1 - 9 6.0 17.3 2.1 8.0 1.0 3.7 4 0 0 4 4 3 0 Domain of unknown function DUF87 AcetylCoA_hydro PF02550.10 CCD23324.1 - 1.7e-70 236.8 0.0 5.7e-70 235.0 0.0 1.9 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 CCD23324.1 - 7.4e-39 132.8 0.0 1.1e-38 132.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.7 CCD23324.1 - 0.044 12.4 0.0 0.078 11.6 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.18 CCD23324.1 - 0.069 12.3 0.0 0.18 10.9 0.0 1.8 2 0 0 2 2 2 0 Coenzyme A transferase Pkinase PF00069.20 CCD23325.1 - 1.9e-72 243.5 0.0 2.2e-72 243.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23325.1 - 2.3e-32 112.1 0.0 3e-32 111.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD23325.1 - 0.002 17.1 0.1 0.011 14.7 0.0 2.1 1 1 2 3 3 3 1 Kinase-like Kdo PF06293.9 CCD23325.1 - 0.0049 15.9 0.2 0.0081 15.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD23325.1 - 0.093 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BNR PF02012.15 CCD23326.1 - 3.4e-12 44.2 46.0 0.2 11.5 0.1 12.8 13 0 0 13 13 13 8 BNR/Asp-box repeat BNR_2 PF13088.1 CCD23326.1 - 1.9e-08 33.9 5.9 0.059 12.6 0.2 5.9 5 2 2 7 7 7 3 BNR repeat-like domain Mo-co_dimer PF03404.11 CCD23326.1 - 0.00037 20.1 0.9 4.4 6.9 0.0 4.9 6 0 0 6 6 6 2 Mo-co oxidoreductase dimerisation domain Exo_endo_phos PF03372.18 CCD23328.1 - 4.7e-15 56.2 0.0 7.1e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 CCD23328.1 - 1.3e-10 41.0 1.4 1.3e-09 37.8 0.2 2.8 2 0 0 2 2 2 1 GRF zinc finger Exo_endo_phos_2 PF14529.1 CCD23328.1 - 6.2e-10 38.7 0.0 1.4e-08 34.3 0.0 2.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Rft-1 PF04506.8 CCD23329.1 - 2.6e-165 550.9 53.9 2.6e-164 547.6 37.4 2.2 1 1 0 1 1 1 1 Rft protein DUF2061 PF09834.4 CCD23329.1 - 3.2 7.9 7.3 0.17 12.1 0.2 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) CBFD_NFYB_HMF PF00808.18 CCD23330.1 - 2.4e-26 91.5 0.0 3.6e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCD23330.1 - 9.8e-07 28.8 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 CCD23330.1 - 0.014 15.6 0.2 0.065 13.5 0.0 1.9 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.8 CCD23330.1 - 0.052 13.2 0.0 0.09 12.5 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF4611 PF15387.1 CCD23330.1 - 0.091 12.9 0.5 6.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Lon_C PF05362.8 CCD23331.1 - 3.5e-67 225.6 0.0 2.1e-66 223.1 0.0 2.4 3 0 0 3 3 3 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 CCD23331.1 - 5.4e-35 120.9 12.8 2.3e-34 118.8 8.8 2.2 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 CCD23331.1 - 1.9e-23 83.1 0.0 7.1e-23 81.2 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCD23331.1 - 5.8e-07 29.3 0.0 1.4e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 CCD23331.1 - 3.6e-06 26.4 0.0 7.7e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_17 PF13207.1 CCD23331.1 - 1.4e-05 25.8 0.3 0.00029 21.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CCD23331.1 - 0.00013 22.0 0.1 0.0057 16.7 0.0 3.1 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CCD23331.1 - 0.00035 20.6 0.3 0.0065 16.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CCD23331.1 - 0.00097 19.0 0.0 0.004 17.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCD23331.1 - 0.0011 19.2 6.9 0.0065 16.7 0.0 4.0 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 CCD23331.1 - 0.0019 18.3 0.0 0.074 13.2 0.0 2.7 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.7 CCD23331.1 - 0.0021 17.1 0.0 0.017 14.1 0.0 2.4 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CCD23331.1 - 0.037 13.4 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.17 CCD23331.1 - 0.039 13.8 0.0 0.039 13.8 0.0 2.6 3 0 0 3 3 2 0 Shikimate kinase DUF258 PF03193.11 CCD23331.1 - 0.063 12.4 0.3 0.18 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCD23331.1 - 0.14 11.4 0.0 0.39 10.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 CCD23332.1 - 1.2e-141 471.2 0.2 1.8e-141 470.7 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 CCD23332.1 - 2.2e-27 95.9 35.1 2.2e-27 95.9 24.3 3.9 4 1 1 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 CCD23332.1 - 8.5e-14 52.0 0.1 2.3e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCD23332.1 - 2.8e-09 36.4 0.0 2.7e-07 29.9 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCD23332.1 - 1.7e-07 31.0 0.0 3.8e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCD23332.1 - 0.00035 20.1 0.0 0.002 17.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCD23332.1 - 0.0015 18.0 0.1 0.011 15.2 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 CCD23332.1 - 0.019 15.1 0.0 0.065 13.4 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cut8_N PF14482.1 CCD23332.1 - 3.3 7.7 6.9 0.3 11.1 0.7 2.4 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Nol1_Nop2_Fmu PF01189.12 CCD23333.1 - 1.4e-70 237.8 0.0 5.6e-53 180.1 0.0 2.7 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CCD23333.1 - 0.00014 21.9 0.0 0.00034 20.6 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase RrnaAD PF00398.15 CCD23333.1 - 0.0051 15.8 0.0 0.0081 15.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 CCD23333.1 - 0.0095 16.5 0.0 0.02 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Nitr_red_alph_N PF14710.1 CCD23333.1 - 1.5 9.1 4.2 0.77 10.0 1.1 1.9 2 0 0 2 2 2 0 Respiratory nitrate reductase alpha N-terminal UAF_Rrn10 PF05234.6 CCD23334.1 - 9.7e-47 157.9 0.1 1.3e-46 157.5 0.1 1.1 1 0 0 1 1 1 1 UAF complex subunit Rrn10 GDI PF00996.13 CCD23335.1 - 2.2e-210 698.5 0.2 2.7e-210 698.2 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CCD23335.1 - 0.012 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Ribosomal_S15 PF00312.17 CCD23336.1 - 1.1e-21 76.3 0.2 1.2e-21 76.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S15 RPAP2_Rtr1 PF04181.8 CCD23337.1 - 1.6e-19 69.7 0.3 3.5e-19 68.6 0.2 1.6 1 0 0 1 1 1 1 Rtr1/RPAP2 family DUF747 PF05346.6 CCD23338.1 - 3.1e-89 299.3 21.5 4.1e-89 298.9 14.9 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family COX15-CtaA PF02628.10 CCD23339.1 - 1.6e-99 332.6 5.4 1.9e-99 332.3 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF1689 PF07954.6 CCD23339.1 - 0.011 15.6 0.4 4.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) HhH-GPD PF00730.20 CCD23340.1 - 3.2e-10 40.2 0.0 7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Sugar_tr PF00083.19 CCD23341.1 - 1.1e-158 528.5 40.9 1.3e-158 528.3 28.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD23341.1 - 2.6e-26 92.1 33.8 3.4e-26 91.7 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LMF1 PF06762.9 CCD23341.1 - 0.001 17.9 0.6 0.0017 17.2 0.4 1.3 1 0 0 1 1 1 1 Lipase maturation factor PDR_CDR PF06422.7 CCD23341.1 - 9.7 5.9 8.6 10 5.8 0.0 3.5 3 0 0 3 3 3 0 CDR ABC transporter Copper-fist PF00649.13 CCD23342.1 - 2.9e-22 77.5 1.1 5.9e-22 76.5 0.8 1.6 1 0 0 1 1 1 1 Copper fist DNA binding domain zf-C2H2 PF00096.21 CCD23343.1 - 1e-07 31.8 3.8 0.0085 16.3 0.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD23343.1 - 1.8e-07 30.9 3.2 0.00073 19.7 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD23343.1 - 0.00026 21.1 8.8 0.003 17.7 0.1 4.2 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.2 CCD23343.1 - 0.004 17.2 1.3 0.64 10.3 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCD23343.1 - 0.024 14.7 0.1 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CCD23343.1 - 0.07 13.2 1.4 0.13 12.3 0.3 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Di19 PF05605.7 CCD23343.1 - 0.093 12.8 0.7 0.25 11.4 0.5 1.7 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-tcix PF14952.1 CCD23343.1 - 0.94 8.8 4.1 14 5.1 2.8 2.3 1 1 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding MUG113 PF13455.1 CCD23344.1 - 1.3e-08 35.1 0.1 6.6e-07 29.6 0.1 2.4 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 CCD23344.1 - 3.5e-07 30.5 0.3 8.7e-05 22.8 0.2 2.7 1 1 0 1 1 1 1 T5orf172 domain Nup96 PF12110.3 CCD23344.1 - 0.1 11.7 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Nuclear protein 96 LUC7 PF03194.10 CCD23346.1 - 4.8e-67 226.1 8.0 6.8e-67 225.6 5.5 1.2 1 0 0 1 1 1 1 LUC7 N_terminus RTBV_P12 PF06361.6 CCD23346.1 - 0.15 12.3 0.8 0.28 11.4 0.4 1.6 1 1 0 1 1 1 0 Rice tungro bacilliform virus P12 protein DUF2418 PF10332.4 CCD23347.1 - 8.5e-24 83.7 2.8 8.5e-24 83.7 1.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Prenyltrans PF00432.16 CCD23348.1 - 1.8e-42 142.5 7.6 6e-13 48.1 0.0 5.3 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCD23348.1 - 2.7e-23 82.5 0.1 6.1e-14 52.3 0.0 3.1 1 1 1 2 2 2 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCD23348.1 - 1.5e-06 28.1 0.0 0.001 19.0 0.0 2.4 1 1 2 3 3 3 3 Prenyltransferase-like UBX PF00789.15 CCD23349.1 - 1.3e-09 37.9 0.0 9e-09 35.2 0.0 2.3 2 0 0 2 2 2 1 UBX domain SRP14 PF02290.10 CCD23350.1 - 9.7e-22 76.6 0.3 2.3e-21 75.5 0.2 1.6 1 1 0 1 1 1 1 Signal recognition particle 14kD protein ParB PF08775.5 CCD23350.1 - 0.055 13.7 0.3 0.089 13.1 0.2 1.4 1 0 0 1 1 1 0 ParB family LigT_PEase PF02834.11 CCD23350.1 - 0.093 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 LigT like Phosphoesterase PMT PF02366.13 CCD23351.1 - 5.2e-67 225.7 25.8 8.6e-67 225.0 17.9 1.4 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCD23351.1 - 4.2e-41 140.5 0.9 6.5e-41 139.9 0.7 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.1 CCD23351.1 - 3e-05 23.9 21.3 3e-05 23.9 14.8 2.7 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT PF02366.13 CCD23352.1 - 8e-81 270.9 18.8 8e-81 270.9 13.0 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCD23352.1 - 2.1e-51 174.1 0.0 3.2e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 MIR domain DNA_pol_B PF00136.16 CCD23353.1 - 1.2e-136 456.2 1.5 1.6e-136 455.7 1.0 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CCD23353.1 - 3.3e-86 289.0 0.0 5.4e-86 288.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CCD23353.1 - 5.3e-24 84.0 4.2 1.1e-23 83.0 2.9 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 CCD23353.1 - 6.5e-05 21.7 4.8 0.00029 19.6 0.8 2.3 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.4 CCD23353.1 - 0.00038 20.0 0.0 0.00072 19.1 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 CCD23353.1 - 0.00095 19.0 1.0 0.023 14.4 0.3 2.9 2 1 0 2 2 2 1 RNase_H superfamily Pkinase PF00069.20 CCD23354.1 - 1.2e-72 244.2 0.1 1.5e-72 243.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23354.1 - 1e-37 129.6 0.0 1.3e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CCD23354.1 - 8.9e-18 64.1 0.7 2.6e-17 62.6 0.5 1.9 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 CCD23354.1 - 0.013 14.4 0.8 2.6 6.9 0.1 2.5 2 1 1 3 3 3 0 Kinase-like RIO1 PF01163.17 CCD23354.1 - 0.042 13.1 2.0 0.57 9.5 1.4 2.2 1 1 0 1 1 1 0 RIO1 family Kdo PF06293.9 CCD23354.1 - 0.082 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ArsA_ATPase PF02374.10 CCD23355.1 - 8e-117 389.6 0.1 9.3e-117 389.4 0.0 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CCD23355.1 - 2.4e-12 46.6 0.4 4.2e-12 45.8 0.3 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.13 CCD23355.1 - 0.0007 18.8 0.0 0.0015 17.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.1 CCD23355.1 - 0.0029 17.5 0.0 0.029 14.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCD23355.1 - 0.02 14.3 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CCD23355.1 - 0.021 14.2 0.1 0.51 9.7 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PhoH PF02562.11 CCD23355.1 - 0.037 13.2 0.0 0.073 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 CCD23355.1 - 0.15 10.9 0.0 0.3 9.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Unstab_antitox PF09720.5 CCD23356.1 - 0.4 10.3 17.4 0.75 9.5 0.3 3.8 3 1 0 3 3 3 0 Putative addiction module component FlpD PF02662.11 CCD23356.1 - 0.62 9.7 6.5 0.16 11.6 0.4 2.8 2 1 1 3 3 3 0 Methyl-viologen-reducing hydrogenase, delta subunit DUF1387 PF07139.6 CCD23356.1 - 4 6.9 29.8 5.9 6.4 20.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Macoilin PF09726.4 CCD23356.1 - 6.9 4.8 28.7 8.7 4.4 19.9 1.1 1 0 0 1 1 1 0 Transmembrane protein zf-met PF12874.2 CCD23357.1 - 1e-05 25.5 1.2 2.2e-05 24.4 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCD23357.1 - 7.1e-05 22.8 1.4 0.00014 21.9 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CCD23357.1 - 0.21 12.0 1.9 0.45 10.9 1.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CCD23357.1 - 0.31 11.0 1.8 0.79 9.7 1.3 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 CCD23357.1 - 0.4 11.1 2.6 0.87 10.0 0.8 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger PCI PF01399.22 CCD23358.1 - 3.8e-16 59.3 2.1 6.2e-16 58.6 0.0 2.4 3 0 0 3 3 3 1 PCI domain TPR_16 PF13432.1 CCD23358.1 - 7.7e-06 26.4 1.5 0.003 18.1 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCD23358.1 - 1.6e-05 24.1 1.4 3.6e-05 22.9 0.9 1.7 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_20 PF14561.1 CCD23358.1 - 3e-05 24.0 3.4 0.007 16.4 0.2 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCD23358.1 - 0.0024 17.4 8.4 0.099 12.3 0.1 3.7 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.1 CCD23358.1 - 0.003 17.4 6.5 0.07 13.0 0.8 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCD23358.1 - 0.012 15.8 5.7 4.7 7.6 0.1 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_21 PF09976.4 CCD23358.1 - 0.037 13.9 8.6 0.92 9.4 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Rapamycin_bind PF08771.6 CCD23358.1 - 0.079 13.0 2.9 18 5.5 0.0 3.8 3 1 1 4 4 4 0 Rapamycin binding domain TPR_2 PF07719.12 CCD23358.1 - 0.16 11.9 13.6 0.75 9.8 0.2 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 CCD23358.1 - 0.83 9.8 16.3 0.16 12.1 1.3 4.2 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 UDPGP PF01704.13 CCD23359.1 - 1.9e-47 161.7 0.0 2.7e-47 161.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CCD23359.1 - 0.06 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain LisH PF08513.6 CCD23360.1 - 7.7e-06 25.4 3.6 1.6e-05 24.4 2.5 1.6 1 0 0 1 1 1 1 LisH Peptidase_M22 PF00814.20 CCD23361.1 - 1.8e-57 194.9 0.0 2.2e-57 194.6 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family BcrAD_BadFG PF01869.15 CCD23361.1 - 0.12 11.6 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Nse4_C PF08743.5 CCD23362.1 - 1.5e-23 82.5 1.2 1.5e-23 82.5 0.8 2.3 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 CCD23362.1 - 1.8e-13 50.1 0.5 8.6e-13 47.9 0.0 2.5 2 1 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE Homeobox PF00046.24 CCD23363.1 - 2.1e-16 59.2 4.2 3.9e-16 58.3 2.9 1.5 1 0 0 1 1 1 1 Homeobox domain TLP-20 PF06088.6 CCD23363.1 - 0.0037 16.9 10.8 0.0037 16.9 7.5 4.3 4 0 0 4 4 4 3 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Homeobox_KN PF05920.6 CCD23363.1 - 0.0046 16.6 0.7 0.014 15.0 0.5 1.9 1 0 0 1 1 1 1 Homeobox KN domain TPR_12 PF13424.1 CCD23364.1 - 1.7e-08 34.3 0.3 0.042 13.7 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCD23364.1 - 1.8e-08 33.9 8.2 7.8e-05 22.2 0.5 3.8 4 1 2 6 6 6 3 TPR repeat TPR_2 PF07719.12 CCD23364.1 - 1e-07 31.2 6.9 0.0051 16.6 0.2 5.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCD23364.1 - 0.00028 20.4 15.0 0.0019 17.8 0.4 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 CCD23364.1 - 0.0027 17.8 5.5 0.69 10.0 0.1 3.6 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CCD23364.1 - 0.0057 16.2 10.8 0.27 10.9 0.6 4.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCD23364.1 - 0.0084 16.7 0.0 9.8 6.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCD23364.1 - 0.044 14.2 0.5 1.5e+02 3.2 0.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 CCD23364.1 - 0.23 12.1 3.9 17 6.2 0.0 4.2 5 0 0 5 5 5 0 Sel1 repeat Pkinase PF00069.20 CCD23365.1 - 1.2e-72 244.2 0.0 1.3e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23365.1 - 7.2e-32 110.4 0.0 1.8e-31 109.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD23365.1 - 0.002 17.1 0.0 0.0059 15.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CCD23365.1 - 0.0041 16.8 0.1 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF676 PF05057.9 CCD23366.1 - 9.4e-54 182.0 0.2 1.6e-53 181.2 0.2 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 CCD23366.1 - 0.013 14.4 0.1 0.2 10.6 0.0 2.2 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 CCD23366.1 - 0.033 13.8 0.0 0.062 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.8 CCD23366.1 - 0.043 13.4 0.5 0.12 11.8 0.0 2.0 2 1 0 2 2 2 0 PGAP1-like protein SH3_9 PF14604.1 CCD23367.1 - 3e-07 29.9 0.1 5.8e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCD23367.1 - 1.3e-05 24.5 0.2 3.9e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 SH3 domain Transglut_core PF01841.14 CCD23367.1 - 0.00029 21.0 0.0 0.00071 19.7 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 CCD23367.1 - 0.0015 18.0 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Nup84_Nup100 PF04121.8 CCD23368.1 - 1.2e-208 694.2 20.0 1.5e-208 693.8 13.9 1.1 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF1762 PF08574.5 CCD23369.1 - 2.8e-20 72.5 16.1 2.8e-20 72.5 11.2 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF1762) adh_short PF00106.20 CCD23370.1 - 2.4e-27 95.8 0.0 4.2e-27 95.0 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCD23370.1 - 2.4e-11 43.6 0.0 2e-10 40.6 0.0 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCD23370.1 - 3e-11 43.5 0.0 4.1e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 CCD23370.1 - 0.001 17.8 0.1 0.0016 17.2 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCD23370.1 - 0.0051 16.2 0.0 0.0083 15.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCD23370.1 - 0.027 14.4 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding ACP53EA PF06313.6 CCD23370.1 - 0.04 13.8 0.1 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 Drosophila ACP53EA protein Polysacc_synt_2 PF02719.10 CCD23370.1 - 0.12 11.2 0.6 0.19 10.5 0.4 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 CCD23370.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain PX PF00787.19 CCD23371.1 - 3.3e-25 88.0 0.2 1.4e-24 86.0 0.0 2.1 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 CCD23371.1 - 7.6e-10 38.4 5.9 1.3e-06 27.8 0.1 2.4 2 0 0 2 2 2 2 Vps5 C terminal like CtsR PF05848.6 CCD23371.1 - 5.6 6.9 9.1 1.6 8.6 0.3 3.5 4 0 0 4 4 4 0 Firmicute transcriptional repressor of class III stress genes (CtsR) SpoU_methylase PF00588.14 CCD23372.1 - 5.6e-26 91.1 0.0 4.7e-25 88.1 0.0 2.5 2 1 0 2 2 2 1 SpoU rRNA Methylase family DUF3440 PF11922.3 CCD23372.1 - 0.0095 15.5 0.3 0.044 13.3 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3440) ISG65-75 PF11727.3 CCD23373.1 - 0.014 14.4 5.6 0.017 14.1 3.9 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein Noc2 PF03715.8 CCD23373.1 - 0.029 13.2 0.3 0.036 12.9 0.2 1.1 1 0 0 1 1 1 0 Noc2p family Snapin_Pallidin PF14712.1 CCD23373.1 - 0.09 13.0 2.5 0.15 12.3 1.7 1.4 1 0 0 1 1 1 0 Snapin/Pallidin RhoGAP PF00620.22 CCD23373.1 - 0.12 12.0 1.3 0.32 10.6 0.1 2.0 1 1 1 2 2 2 0 RhoGAP domain DUF2951 PF11166.3 CCD23373.1 - 9.6 6.1 8.5 1.6 8.5 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) Mito_carr PF00153.22 CCD23374.1 - 9.9e-51 169.4 3.7 5.5e-19 67.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Frataxin_Cyay PF01491.11 CCD23375.1 - 3.7e-31 107.1 0.0 5e-31 106.7 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain UCH PF00443.24 CCD23377.1 - 2.6e-42 144.8 27.7 1.8e-41 142.0 19.2 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCD23377.1 - 2.5e-07 30.4 20.7 0.00016 21.2 14.3 4.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SSP160 PF06933.6 CCD23377.1 - 0.035 12.1 6.1 0.049 11.6 4.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 CCD23377.1 - 0.19 11.4 4.9 0.55 9.9 3.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RRM_1 PF00076.17 CCD23378.1 - 7.2e-55 182.5 1.3 4.9e-19 67.7 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD23378.1 - 1.4e-27 95.4 0.2 3.8e-10 39.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD23378.1 - 3.6e-27 93.9 1.2 2.6e-08 33.5 0.3 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCD23378.1 - 0.003 17.3 0.1 0.15 11.8 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.10 CCD23378.1 - 0.044 13.4 0.0 5.4 6.7 0.0 2.5 2 0 0 2 2 2 0 DbpA RNA binding domain Limkain-b1 PF11608.3 CCD23378.1 - 0.068 12.9 0.6 0.41 10.4 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 DUF3421 PF11901.3 CCD23378.1 - 0.081 12.6 0.1 10 5.9 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) Robl_LC7 PF03259.12 CCD23378.1 - 0.14 11.7 0.7 0.26 10.8 0.5 1.4 1 0 0 1 1 1 0 Roadblock/LC7 domain DFP PF04127.10 CCD23379.1 - 6.1e-14 52.0 0.0 1.6e-05 24.5 0.0 3.1 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein Sds3 PF08598.6 CCD23380.1 - 6.2e-56 189.1 4.4 9.1e-56 188.6 3.1 1.2 1 0 0 1 1 1 1 Sds3-like Glyco_transf_15 PF01793.11 CCD23381.1 - 5.5e-119 396.9 24.2 1.2e-118 395.8 16.8 1.5 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Histone PF00125.19 CCD23382.1 - 2.3e-15 56.4 0.3 2.8e-15 56.2 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCD23382.1 - 1.6e-05 24.8 0.1 2.8e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CCD23382.1 - 3.7e-05 23.5 0.2 5.2e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CCD23382.1 - 4.8e-05 23.4 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CCD23382.1 - 0.0013 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CCD23382.1 - 0.0058 16.3 0.1 0.0072 16.0 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 CCD23382.1 - 0.04 14.1 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 CCD23382.1 - 0.13 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 CCD23383.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCD23383.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCD23383.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCD23383.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF2416 PF10315.4 CCD23384.1 - 1.2e-32 112.3 1.4 1.8e-32 111.7 1.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Aa_trans PF01490.13 CCD23385.1 - 3.8e-112 374.7 22.2 4.8e-112 374.4 15.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PepSY_TM_2 PF13703.1 CCD23385.1 - 0.02 15.0 0.6 0.02 15.0 0.4 3.0 4 0 0 4 4 4 0 PepSY-associated TM helix ICE2 PF08426.5 CCD23386.1 - 1.5e-163 544.2 28.5 1.8e-163 543.9 19.8 1.0 1 0 0 1 1 1 1 ICE2 DUF1253 PF06862.7 CCD23387.1 - 8.8e-163 541.7 9.4 1.3e-162 541.1 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) MRP-S25 PF13741.1 CCD23388.1 - 4.9e-89 297.7 6.0 5.7e-89 297.5 4.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 CCD23388.1 - 8.2e-06 25.7 1.8 0.0001 22.2 0.0 2.6 2 1 1 3 3 3 1 Mitochondrial ribosomal protein S23 Iso_dh PF00180.15 CCD23389.1 - 6.8e-105 350.8 0.1 8.5e-105 350.5 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.20 CCD23390.1 - 2.7e-35 121.7 0.0 5.2e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23390.1 - 9.5e-27 93.6 0.0 1.5e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD23390.1 - 2.4e-05 23.4 0.0 4.4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCD23390.1 - 0.049 13.3 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF2431 PF10354.4 CCD23391.1 - 2.2e-58 196.9 0.1 3.8e-58 196.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) CLTH PF10607.4 CCD23392.1 - 3.2e-28 98.2 7.6 3.2e-28 98.2 5.3 3.3 3 2 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain Iso_dh PF00180.15 CCD23393.1 - 3.9e-76 256.2 0.4 4.9e-76 255.9 0.3 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Complex1_LYR_2 PF13233.1 CCD23394.1 - 3.1e-09 37.2 9.5 1.3e-08 35.1 6.6 1.9 1 1 0 1 1 1 1 Complex1_LYR-like DnaG_DnaB_bind PF08278.6 CCD23394.1 - 0.029 14.5 0.3 0.062 13.5 0.2 1.6 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding AAA_21 PF13304.1 CCD23394.1 - 0.16 11.8 7.3 0.19 11.6 5.0 1.1 1 0 0 1 1 1 0 AAA domain MutL PF13941.1 CCD23395.1 - 0.2 9.9 0.0 0.32 9.2 0.0 1.2 1 0 0 1 1 1 0 MutL protein Diphthamide_syn PF01866.12 CCD23396.1 - 3.8e-114 381.0 0.0 4.7e-114 380.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SHQ1 PF04925.10 CCD23397.1 - 4.8e-69 231.6 0.4 7.5e-69 230.9 0.3 1.2 1 0 0 1 1 1 1 SHQ1 protein PH PF00169.24 CCD23398.1 - 1.6e-15 57.1 0.6 4.6e-15 55.6 0.4 1.8 1 0 0 1 1 1 1 PH domain BAF1_ABF1 PF04684.8 CCD23398.1 - 1.5 7.5 17.8 2.9 6.6 12.4 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Mob1_phocein PF03637.12 CCD23399.1 - 9.5e-71 237.0 0.0 1.3e-70 236.6 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family 6PF2K PF01591.13 CCD23400.1 - 1.3e-83 279.4 0.2 2.6e-83 278.4 0.1 1.5 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCD23400.1 - 3.6e-31 108.3 0.1 2.8e-29 102.2 0.0 2.8 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CCD23400.1 - 5.3e-08 32.8 0.1 2.2e-07 30.8 0.0 2.1 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 CCD23400.1 - 3.8e-06 27.7 0.1 1.8e-05 25.5 0.0 2.3 2 2 0 2 2 2 1 AAA domain SlyX PF04102.7 CCD23400.1 - 0.0014 18.9 0.1 0.0042 17.4 0.1 1.9 1 0 0 1 1 1 1 SlyX MMR_HSR1 PF01926.18 CCD23400.1 - 0.0016 18.3 0.6 0.1 12.5 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase KTI12 PF08433.5 CCD23400.1 - 0.0033 16.6 0.7 0.0088 15.2 0.0 2.0 2 0 0 2 2 2 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 CCD23400.1 - 0.0052 15.9 0.0 0.014 14.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.15 CCD23400.1 - 0.0071 16.0 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.1 CCD23400.1 - 0.035 14.4 0.7 0.33 11.2 0.0 3.0 3 1 0 3 3 3 0 AAA domain Metallopep PF12044.3 CCD23401.1 - 2.4e-164 546.8 0.0 3.1e-164 546.4 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 CCD23401.1 - 8.3e-05 22.4 0.0 0.00027 20.8 0.0 1.9 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_3 PF13582.1 CCD23401.1 - 0.013 15.9 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CCD23401.1 - 0.048 13.7 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CCD23401.1 - 0.19 11.6 0.1 0.31 10.9 0.1 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Methyltransf_16 PF10294.4 CCD23402.1 - 0.044 13.2 0.1 3.7 6.9 0.0 2.5 3 0 0 3 3 3 0 Putative methyltransferase COX4 PF02936.9 CCD23403.1 - 9.4e-36 122.6 0.2 1e-35 122.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Ank_2 PF12796.2 CCD23404.1 - 1.9e-48 162.6 1.9 1.5e-14 54.0 0.1 4.4 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CCD23404.1 - 2.1e-38 128.2 4.7 3e-09 36.2 0.3 6.5 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 CCD23404.1 - 1.4e-34 117.7 1.6 1.2e-09 38.4 0.0 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD23404.1 - 8.1e-29 96.8 1.2 1.5e-06 27.8 0.3 6.9 6 1 1 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 CCD23404.1 - 5.8e-28 96.2 3.1 1.8e-08 34.3 0.1 5.8 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Porin_3 PF01459.17 CCD23405.1 - 4.9e-58 196.5 0.4 5.5e-58 196.4 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic porin DUF929 PF06053.6 CCD23406.1 - 0.0009 18.4 0.1 0.0025 16.9 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF929) Nucleoporin_FG PF13634.1 CCD23406.1 - 0.16 12.2 131.2 0.12 12.6 20.2 5.6 2 1 3 5 5 5 0 Nucleoporin FG repeat region Aminotran_1_2 PF00155.16 CCD23407.1 - 4.7e-67 226.4 0.0 5.5e-67 226.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 CCD23407.1 - 0.0053 15.4 0.0 0.0076 14.9 0.0 1.2 1 0 0 1 1 1 1 Allinase DUF2976 PF11190.3 CCD23408.1 - 0.0052 16.2 0.1 0.009 15.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2976) MIG-14_Wnt-bd PF06664.7 CCD23408.1 - 0.032 13.0 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Alpha_GJ PF03229.8 CCD23408.1 - 2.7 8.3 15.2 0.47 10.7 2.3 2.5 2 0 0 2 2 2 0 Alphavirus glycoprotein J Ras PF00071.17 CCD23409.1 - 5.8e-57 191.5 0.2 8.7e-57 191.0 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD23409.1 - 2e-17 63.8 0.1 5.8e-17 62.2 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCD23409.1 - 2e-09 36.9 0.1 4.7e-09 35.7 0.0 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.15 CCD23409.1 - 3.2e-05 22.8 0.1 3.9e-05 22.5 0.1 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Gtr1_RagA PF04670.7 CCD23409.1 - 0.00021 20.5 0.1 0.00029 20.0 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCD23409.1 - 0.00023 21.1 0.0 0.00055 19.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCD23409.1 - 0.00061 19.0 0.0 0.001 18.3 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Mss4 PF04421.8 CCD23409.1 - 0.0015 18.2 0.4 0.003 17.3 0.3 1.4 1 0 0 1 1 1 1 Mss4 protein AAA_28 PF13521.1 CCD23409.1 - 0.0019 18.1 0.0 0.15 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCD23409.1 - 0.0078 15.9 0.0 0.013 15.1 0.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase IPP-2 PF04979.9 CCD23409.1 - 0.0088 16.2 0.1 0.12 12.6 0.1 2.1 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Dynamin_N PF00350.18 CCD23409.1 - 0.47 10.2 3.4 1.6 8.5 0.0 2.4 2 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.22 CCD23409.1 - 0.82 9.9 6.1 3.8 7.7 4.2 2.1 1 1 0 1 1 1 0 ABC transporter Myb_DNA-bind_4 PF13837.1 CCD23410.1 - 0.00064 19.8 0.5 0.0017 18.4 0.1 1.9 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain Rap1-DNA-bind PF09197.5 CCD23410.1 - 0.021 15.3 0.9 0.061 13.8 0.6 1.8 1 0 0 1 1 1 0 Rap1, DNA-binding MFS_1 PF07690.11 CCD23411.1 - 5.4e-41 140.4 28.9 1.1e-36 126.2 10.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily SUN PF03856.8 CCD23413.1 - 3e-105 351.0 15.4 3e-105 351.0 10.6 1.5 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) TFIIA PF03153.8 CCD23413.1 - 2.5 7.9 11.3 3.3 7.5 7.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.20 CCD23414.1 - 1.3e-25 90.2 0.0 1.9e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCD23414.1 - 1.5e-14 54.3 0.0 2e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCD23414.1 - 6.3e-06 25.9 0.0 9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCD23414.1 - 0.00022 20.7 0.0 0.00061 19.3 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCD23414.1 - 0.00091 19.2 0.0 0.0016 18.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 CCD23414.1 - 0.001 18.2 0.1 0.018 14.2 0.1 2.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 CCD23414.1 - 0.0036 16.2 0.0 0.0053 15.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Transket_pyr PF02779.19 CCD23415.1 - 4.4e-65 218.5 0.0 8.4e-65 217.5 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CCD23415.1 - 4.7e-54 183.1 0.0 6.3e-54 182.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component LuxE PF04443.7 CCD23415.1 - 0.11 11.1 0.3 0.18 10.4 0.2 1.3 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE Transposase_mut PF00872.13 CCD23416.1 - 5.4e-06 25.1 0.4 1.3e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Transposase, Mutator family MULE PF10551.4 CCD23416.1 - 7e-05 22.9 0.0 0.00022 21.3 0.0 1.9 1 0 0 1 1 1 1 MULE transposase domain Ribosomal_L6 PF00347.18 CCD23417.1 - 4.6e-28 97.5 12.4 3.6e-14 52.9 3.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 LRR_6 PF13516.1 CCD23417.1 - 0.046 13.7 0.4 1.2 9.4 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeat SNF2_N PF00176.18 CCD23418.1 - 3.2e-84 282.2 0.5 3.2e-84 282.2 0.4 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCD23418.1 - 9.9e-20 70.1 0.0 6.2e-17 61.2 0.0 4.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 CCD23418.1 - 9.5e-19 67.1 0.3 3.6e-18 65.2 0.2 2.1 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 CCD23418.1 - 2.8e-13 49.8 0.0 2.8e-13 49.8 0.0 4.2 4 2 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 CCD23418.1 - 0.00017 21.3 6.0 0.00017 21.3 4.2 2.8 2 0 0 2 2 2 1 HSA Fungal_trans PF04082.13 CCD23419.1 - 4.6e-38 130.5 0.6 1.2e-37 129.2 0.4 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD23419.1 - 1.1e-11 44.3 11.6 2e-11 43.5 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fork_head PF00250.13 CCD23420.1 - 4.1e-29 100.4 0.2 8.7e-29 99.4 0.2 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CCD23420.1 - 1.6e-06 28.1 0.0 4.2e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 FHA domain Ribosomal_L13 PF00572.13 CCD23422.1 - 1.7e-25 89.5 0.0 2.9e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 Mito_carr PF00153.22 CCD23423.1 - 1.3e-62 207.4 0.5 2.4e-24 84.8 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TMEM61 PF15105.1 CCD23424.1 - 0.34 10.4 2.6 0.46 9.9 0.0 2.2 2 0 0 2 2 2 0 TMEM61 protein family DUF883 PF05957.8 CCD23425.1 - 0.016 15.5 6.7 6.3 7.2 0.6 4.2 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 CCD23425.1 - 0.15 11.5 8.9 0.2 11.1 2.6 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4407 PF14362.1 CCD23425.1 - 0.47 9.3 21.6 1.6 7.5 2.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4398 PF14346.1 CCD23425.1 - 0.7 9.9 14.5 2.2 8.4 4.8 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4398) DMPK_coil PF08826.5 CCD23425.1 - 2.1 8.3 7.5 0.46 10.4 0.2 2.9 2 1 0 2 2 2 0 DMPK coiled coil domain like Peptidase_M1 PF01433.15 CCD23426.1 - 8.8e-73 245.6 9.8 1.4e-72 245.0 6.8 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CCD23426.1 - 2.5e-18 66.4 1.6 6.6e-18 65.0 1.1 1.7 1 1 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CCD23426.1 - 1.8e-11 44.1 0.4 1.8e-11 44.1 0.3 1.7 2 0 0 2 2 2 1 Peptidase MA superfamily DUF2265 PF10023.4 CCD23426.1 - 0.01 15.0 1.5 0.012 14.8 0.1 1.7 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) Tropomyosin_1 PF12718.2 CCD23427.1 - 1.3e-46 157.9 45.9 1.6e-46 157.7 31.8 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 CCD23427.1 - 1.2e-06 27.8 42.1 0.0017 17.4 12.8 2.1 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.4 CCD23427.1 - 2e-05 24.5 26.4 0.00011 22.2 10.0 2.1 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein ATG16 PF08614.6 CCD23427.1 - 0.00023 21.0 36.0 0.0016 18.2 10.0 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Laminin_II PF06009.7 CCD23427.1 - 0.002 17.8 24.3 0.0087 15.8 8.8 2.1 1 1 1 2 2 2 1 Laminin Domain II CENP-F_leu_zip PF10473.4 CCD23427.1 - 0.0022 17.8 9.5 0.0022 17.8 6.6 2.7 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 CCD23427.1 - 0.0025 16.8 43.7 0.081 11.9 14.5 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 MbeD_MobD PF04899.7 CCD23427.1 - 0.003 17.4 2.3 0.003 17.4 1.6 2.8 2 1 1 3 3 3 1 MbeD/MobD like CENP-K PF11802.3 CCD23427.1 - 0.0063 15.7 8.6 0.0063 15.7 6.0 2.1 1 1 1 2 2 2 1 Centromere-associated protein K GAS PF13851.1 CCD23427.1 - 0.0069 15.6 40.3 0.022 13.9 21.1 2.2 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding bZIP_2 PF07716.10 CCD23427.1 - 0.016 15.0 5.4 0.016 15.0 3.7 4.8 3 3 2 5 5 5 0 Basic region leucine zipper FlaC_arch PF05377.6 CCD23427.1 - 0.02 14.7 28.9 0.52 10.2 1.5 4.5 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) WXG100 PF06013.7 CCD23427.1 - 0.052 13.5 15.3 0.44 10.5 2.5 3.9 1 1 1 3 3 3 0 Proteins of 100 residues with WXG DUF3584 PF12128.3 CCD23427.1 - 0.059 10.6 32.3 0.066 10.5 22.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3287 PF11690.3 CCD23427.1 - 0.08 13.0 11.5 0.077 13.0 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Clr5 PF14420.1 CCD23427.1 - 0.083 12.7 0.9 0.083 12.7 0.6 2.6 4 0 0 4 4 2 0 Clr5 domain NPV_P10 PF05531.7 CCD23427.1 - 0.099 12.9 14.8 6.9 6.9 0.1 3.9 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Mod_r PF07200.8 CCD23427.1 - 0.13 12.1 32.9 0.15 11.9 8.4 2.9 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Filament PF00038.16 CCD23427.1 - 0.13 11.6 33.8 0.35 10.2 8.9 2.0 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 CCD23427.1 - 0.14 11.3 6.8 0.89 8.6 0.7 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Acyl_transf_1 PF00698.16 CCD23427.1 - 0.16 11.2 0.7 0.22 10.8 0.5 1.3 1 0 0 1 1 1 0 Acyl transferase domain TMF_DNA_bd PF12329.3 CCD23427.1 - 0.16 11.7 49.8 0.034 13.9 14.7 3.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding EzrA PF06160.7 CCD23427.1 - 0.18 9.9 29.4 0.55 8.3 19.9 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA BLOC1_2 PF10046.4 CCD23427.1 - 0.22 11.6 32.3 0.35 11.0 7.9 3.7 1 1 3 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF972 PF06156.8 CCD23427.1 - 0.22 11.8 32.7 0.077 13.3 9.9 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 CCD23427.1 - 0.24 10.9 42.3 1.7e+02 1.6 29.3 2.1 1 1 0 1 1 1 0 IncA protein Laminin_I PF06008.9 CCD23427.1 - 0.31 10.3 28.1 4.4 6.5 19.5 2.0 1 1 0 1 1 1 0 Laminin Domain I AAA_27 PF13514.1 CCD23427.1 - 0.31 8.6 27.7 0.83 7.2 19.2 1.6 1 1 0 1 1 1 0 AAA domain ADIP PF11559.3 CCD23427.1 - 0.32 10.9 34.7 0.16 11.8 9.8 2.8 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding ERM PF00769.14 CCD23427.1 - 0.37 10.2 40.3 0.67 9.4 17.3 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DivIVA PF05103.8 CCD23427.1 - 0.55 10.2 34.5 1.3 9.0 8.9 3.1 1 1 2 3 3 3 0 DivIVA protein Prefoldin_2 PF01920.15 CCD23427.1 - 0.59 9.9 43.4 6.4 6.5 3.1 3.3 1 1 2 3 3 3 0 Prefoldin subunit DUF4201 PF13870.1 CCD23427.1 - 0.65 9.4 34.4 8.9 5.7 23.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) CCDC155 PF14662.1 CCD23427.1 - 0.65 9.5 39.7 0.088 12.3 13.8 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 HisKA_3 PF07730.8 CCD23427.1 - 0.67 10.3 7.7 7 7.0 0.1 3.8 2 1 1 3 3 3 0 Histidine kinase AAA_13 PF13166.1 CCD23427.1 - 0.7 8.2 32.6 0.9 7.9 7.0 1.8 1 1 0 1 1 1 0 AAA domain Atg14 PF10186.4 CCD23427.1 - 0.8 8.5 30.1 0.76 8.6 9.0 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Nup54 PF13874.1 CCD23427.1 - 0.94 9.1 21.3 0.81 9.3 10.4 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Ax_dynein_light PF10211.4 CCD23427.1 - 1.1 9.0 39.0 0.23 11.2 9.1 3.1 1 1 2 3 3 3 0 Axonemal dynein light chain DUF3450 PF11932.3 CCD23427.1 - 1.1 8.4 27.3 0.64 9.2 8.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) PilJ PF13675.1 CCD23427.1 - 1.1 9.5 9.7 18 5.6 3.3 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4407 PF14362.1 CCD23427.1 - 1.3 7.8 19.8 1.9 7.3 13.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Lectin_N PF03954.9 CCD23427.1 - 1.4 8.3 13.0 4.2 6.7 4.4 2.5 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Katanin_con80 PF13925.1 CCD23427.1 - 1.5 8.5 14.2 0.33 10.6 2.0 2.9 1 1 2 3 3 3 0 con80 domain of Katanin Vps5 PF09325.5 CCD23427.1 - 1.5 7.9 28.0 1.1 8.4 2.7 3.4 1 1 3 4 4 4 0 Vps5 C terminal like HOOK PF05622.7 CCD23427.1 - 1.5 6.5 32.5 2.1 6.0 22.5 1.1 1 0 0 1 1 1 0 HOOK protein IFT57 PF10498.4 CCD23427.1 - 1.5 7.4 31.7 1.5 7.5 13.2 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Fez1 PF06818.10 CCD23427.1 - 1.6 8.7 28.0 2 8.3 19.4 1.2 1 0 0 1 1 1 0 Fez1 Seryl_tRNA_N PF02403.17 CCD23427.1 - 1.8 8.6 37.5 8 6.5 3.5 3.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF904 PF06005.7 CCD23427.1 - 2.1 8.6 49.1 15 5.9 3.2 4.0 2 1 0 2 2 1 0 Protein of unknown function (DUF904) Glu_syn_central PF04898.9 CCD23427.1 - 2.3 7.4 7.8 3.8 6.6 5.4 1.4 1 1 0 1 1 1 0 Glutamate synthase central domain DinB_2 PF12867.2 CCD23427.1 - 2.5 8.4 5.2 2.2 8.6 1.0 2.6 1 1 1 2 2 2 0 DinB superfamily Fzo_mitofusin PF04799.8 CCD23427.1 - 3.1 7.1 20.8 4.6 6.5 7.3 2.6 1 1 1 2 2 2 0 fzo-like conserved region DUF4200 PF13863.1 CCD23427.1 - 3.6 7.5 44.5 8.7 6.3 13.1 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Sec2p PF06428.6 CCD23427.1 - 3.7 7.4 37.0 3.5 7.5 13.0 3.4 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p DUF869 PF05911.6 CCD23427.1 - 3.8 5.6 36.0 4.5 5.3 19.3 1.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) Spectrin PF00435.16 CCD23427.1 - 4.3 7.6 31.7 2.8 8.2 8.4 3.1 1 1 2 3 3 3 0 Spectrin repeat TBPIP PF07106.8 CCD23427.1 - 4.9 6.6 37.6 27 4.2 7.4 3.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_1 PF00170.16 CCD23427.1 - 5.1 7.1 41.6 5.1 7.1 1.5 4.7 2 1 2 4 4 4 0 bZIP transcription factor DUF3573 PF12097.3 CCD23427.1 - 5.2 5.5 7.8 5.9 5.3 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4559 PF15112.1 CCD23427.1 - 5.4 6.0 25.4 0.96 8.5 14.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Occludin_ELL PF07303.8 CCD23427.1 - 5.8 7.6 23.6 1.9 9.2 0.2 3.1 1 1 3 4 4 4 0 Occludin homology domain OmpH PF03938.9 CCD23427.1 - 6.6 6.6 35.6 1.5e+04 -8.6 24.7 2.1 1 1 0 1 1 0 0 Outer membrane protein (OmpH-like) DUF3552 PF12072.3 CCD23427.1 - 7.5 5.7 39.7 4.8 6.3 3.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF342 PF03961.8 CCD23427.1 - 7.7 4.8 34.7 3.7 5.8 11.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Corona_S2 PF01601.11 CCD23427.1 - 8.4 4.3 7.7 12 3.8 5.4 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein DUF1311 PF07007.7 CCD23427.1 - 8.7 6.5 13.7 0.35 10.9 3.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1311) HORMA PF02301.13 CCD23428.1 - 5.6e-23 81.5 5.0 7.6e-23 81.0 3.5 1.2 1 0 0 1 1 1 1 HORMA domain Gallidermin PF02052.10 CCD23428.1 - 1.8 8.7 4.3 23 5.2 0.0 3.3 2 1 1 3 3 3 0 Gallidermin SKG6 PF08693.5 CCD23429.1 - 8.1e-16 57.0 0.4 8.1e-16 57.0 0.3 3.0 2 0 0 2 2 2 1 Transmembrane alpha-helix domain He_PIG PF05345.7 CCD23429.1 - 2.2e-10 40.3 16.4 4.2e-06 26.6 0.1 5.4 5 0 0 5 5 5 2 Putative Ig domain Rifin_STEVOR PF02009.11 CCD23429.1 - 7.2e-06 25.8 2.7 1.3e-05 25.0 1.9 1.3 1 0 0 1 1 1 1 Rifin/stevor family DUF1180 PF06679.7 CCD23429.1 - 3.5e-05 23.7 0.6 0.0001 22.2 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) TMEM154 PF15102.1 CCD23429.1 - 0.00064 19.4 4.1 0.0025 17.5 2.8 2.1 1 0 0 1 1 1 1 TMEM154 protein family Adeno_E3_CR2 PF02439.10 CCD23429.1 - 0.0013 18.2 0.2 0.0027 17.2 0.2 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 CCD23429.1 - 0.0029 17.9 0.0 0.011 16.1 0.0 2.0 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Cytomega_TRL10 PF06084.6 CCD23429.1 - 0.022 14.5 2.0 0.069 12.9 1.4 1.8 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein Peptidase_M56 PF05569.6 CCD23429.1 - 0.03 13.2 0.7 0.08 11.8 0.5 1.7 1 0 0 1 1 1 0 BlaR1 peptidase M56 Pox_A14 PF05767.7 CCD23429.1 - 0.074 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF793 PF05633.6 CCD23429.1 - 0.075 11.7 8.7 0.12 11.1 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF793) DUF912 PF06024.7 CCD23429.1 - 0.22 11.5 7.9 0.097 12.7 1.4 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EF-hand_4 PF12763.2 CCD23430.1 - 3.1e-51 171.4 4.4 2.2e-49 165.5 1.6 2.6 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 CCD23430.1 - 2.3e-31 108.9 10.2 2.3e-29 102.4 7.1 2.3 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 Sugarporin_N PF11471.3 CCD23430.1 - 0.026 14.1 0.6 0.026 14.1 0.4 2.2 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension EF-hand_1 PF00036.27 CCD23430.1 - 0.026 13.8 1.9 0.066 12.5 1.3 1.8 1 0 0 1 1 1 0 EF hand IncA PF04156.9 CCD23430.1 - 0.032 13.8 3.8 0.051 13.1 2.6 1.4 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 CCD23430.1 - 0.038 13.6 4.6 0.072 12.7 3.2 1.4 1 0 0 1 1 1 0 Mnd1 family Prefoldin_2 PF01920.15 CCD23430.1 - 0.052 13.3 9.1 0.5 10.1 2.0 2.7 2 0 0 2 2 2 0 Prefoldin subunit DUF641 PF04859.7 CCD23430.1 - 0.098 12.4 2.5 0.91 9.2 0.3 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) EF-hand_8 PF13833.1 CCD23430.1 - 0.11 12.0 1.0 0.24 11.0 0.7 1.6 1 0 0 1 1 1 0 EF-hand domain pair DUF4140 PF13600.1 CCD23430.1 - 0.21 12.0 3.3 12 6.3 0.3 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ADIP PF11559.3 CCD23430.1 - 0.28 11.0 7.8 3.9 7.3 0.9 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 CCD23430.1 - 0.33 10.8 3.7 2.4 8.1 0.6 2.7 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ATG16 PF08614.6 CCD23430.1 - 0.37 10.5 8.9 0.58 9.9 1.3 2.6 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) FlxA PF14282.1 CCD23430.1 - 0.39 10.6 12.4 1.5 8.8 3.6 2.5 1 1 1 2 2 2 0 FlxA-like protein Transcrip_act PF04949.8 CCD23430.1 - 0.47 10.0 4.3 2.2 7.8 1.0 3.0 2 1 0 2 2 2 0 Transcriptional activator DUF2408 PF10303.4 CCD23430.1 - 0.83 9.7 5.5 54 3.9 3.8 2.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Cep57_CLD_2 PF14197.1 CCD23430.1 - 3.4 7.6 8.7 2.5 8.1 0.5 2.8 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 Prefoldin PF02996.12 CCD23430.1 - 3.6 7.2 8.2 0.61 9.7 1.9 2.3 2 1 0 2 2 2 0 Prefoldin subunit Cpn60_TCP1 PF00118.19 CCD23431.1 - 4.2e-138 461.0 13.3 4.9e-138 460.7 9.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Transposase_23 PF03017.9 CCD23431.1 - 0.017 14.5 0.2 0.099 12.1 0.0 2.2 2 0 0 2 2 2 0 TNP1/EN/SPM transposase Helicase_C PF00271.26 CCD23433.1 - 4.3e-13 48.9 0.0 1.1e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD23433.1 - 1.1e-06 28.1 0.0 3.3e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase HAP2-GCS1 PF10699.4 CCD23433.1 - 0.033 14.1 0.1 0.078 12.9 0.1 1.6 1 0 0 1 1 1 0 Male gamete fusion factor MKT1_C PF12246.3 CCD23435.1 - 1.3e-63 214.2 4.2 2.4e-63 213.3 2.9 1.5 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CCD23435.1 - 5.9e-28 97.0 3.9 7e-28 96.7 0.0 3.2 5 0 0 5 5 5 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 CCD23435.1 - 6e-20 71.3 0.0 1.7e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCD23435.1 - 3.5e-09 36.6 0.0 1e-08 35.0 0.0 1.9 1 0 0 1 1 1 1 XPG I-region NOA36 PF06524.7 CCD23435.1 - 0.69 9.1 2.0 1 8.5 1.4 1.2 1 0 0 1 1 1 0 NOA36 protein OST3_OST6 PF04756.8 CCD23436.1 - 8.6e-23 80.6 8.4 1.5e-22 79.8 5.8 1.4 1 0 0 1 1 1 1 OST3 / OST6 family TctB PF07331.6 CCD23436.1 - 3.9 7.1 11.7 72 3.0 8.1 2.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family C2 PF00168.25 CCD23437.1 - 1.1e-49 166.1 6.3 2.2e-16 59.4 0.0 4.5 4 0 0 4 4 4 4 C2 domain IncA PF04156.9 CCD23438.1 - 2 7.9 5.5 7.6 6.0 3.8 2.0 1 0 0 1 1 1 0 IncA protein Ras PF00071.17 CCD23439.1 - 1.2e-28 99.4 0.2 1.5e-28 99.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD23439.1 - 5.3e-06 26.9 0.0 9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCD23439.1 - 2.4e-05 23.6 0.2 2.9e-05 23.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCD23439.1 - 0.022 14.2 0.1 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Rep_4 PF05797.6 CCD23439.1 - 0.11 11.1 0.3 0.13 10.8 0.2 1.1 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) PP2C PF00481.16 CCD23440.1 - 6.7e-50 169.8 0.0 1.4e-49 168.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C DUF4298 PF14131.1 CCD23440.1 - 0.05 13.4 0.0 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Transposase_mut PF00872.13 CCD23441.1 - 0.00053 18.6 0.1 0.00067 18.3 0.1 1.1 1 0 0 1 1 1 1 Transposase, Mutator family MgrB PF13998.1 CCD23441.1 - 0.056 13.2 0.1 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 MgrB protein Mem_trans PF03547.13 CCD23443.1 - 1e-93 313.6 0.0 8.2e-93 310.7 0.0 1.9 1 1 0 1 1 1 1 Membrane transport protein AMP-binding PF00501.23 CCD23444.1 - 2.6e-31 108.4 0.0 7.5e-17 60.8 0.0 4.9 4 1 0 4 4 4 3 AMP-binding enzyme DMAP_binding PF06464.6 CCD23444.1 - 3.1e-14 53.4 2.1 3.1e-14 53.4 1.5 3.2 4 0 0 4 4 4 1 DMAP1-binding Domain Arf PF00025.16 CCD23445.1 - 1.9e-71 238.9 0.5 2.2e-71 238.6 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCD23445.1 - 1e-16 60.6 0.0 1.3e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCD23445.1 - 1.9e-13 49.9 1.7 2.3e-09 36.4 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CCD23445.1 - 5.4e-13 48.6 0.1 6.1e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CCD23445.1 - 1.2e-10 40.9 0.0 1.4e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCD23445.1 - 1.9e-08 34.8 0.0 2.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCD23445.1 - 1.8e-06 27.8 0.1 2.7e-06 27.3 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CCD23445.1 - 0.022 13.8 0.2 0.046 12.7 0.1 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_14 PF13173.1 CCD23445.1 - 0.28 11.0 2.1 2.3 8.1 1.4 2.1 1 1 0 1 1 1 0 AAA domain Rib_5-P_isom_A PF06026.9 CCD23446.1 - 2.7e-58 196.1 0.0 3.4e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CCD23446.1 - 0.014 15.0 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain Ribosomal_S7e PF01251.13 CCD23447.1 - 5.7e-22 78.1 0.1 6.1e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF2951 PF11166.3 CCD23448.1 - 0.14 12.0 0.2 0.35 10.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Nucleoporin_FG PF13634.1 CCD23449.1 - 2.4e-07 30.9 30.1 2.4e-07 30.9 20.9 8.5 2 1 3 5 5 5 2 Nucleoporin FG repeat region Glyco_transf_15 PF01793.11 CCD23450.1 - 1.1e-147 491.3 12.5 1.3e-147 491.0 8.7 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Mito_carr PF00153.22 CCD23451.1 - 1.3e-59 197.9 5.7 7.3e-21 73.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2102 PF09875.4 CCD23451.1 - 0.11 11.9 0.1 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2102) Ras PF00071.17 CCD23452.1 - 1.1e-56 190.6 0.7 2e-56 189.8 0.5 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD23452.1 - 2.9e-19 69.7 0.2 2.9e-19 69.7 0.1 2.2 2 1 1 3 3 3 1 Miro-like protein Arf PF00025.16 CCD23452.1 - 1.7e-09 37.1 0.8 6e-09 35.3 0.1 2.0 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCD23452.1 - 1.4e-05 25.0 0.2 5e-05 23.2 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCD23452.1 - 1.6e-05 24.4 0.9 1.6e-05 24.4 0.6 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain GAGA_bind PF06217.7 CCD23452.1 - 0.016 15.2 9.7 0.021 14.7 6.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family AAA_25 PF13481.1 CCD23452.1 - 0.099 12.0 0.2 0.23 10.8 0.1 1.8 1 1 0 1 1 1 0 AAA domain FAM163 PF15069.1 CCD23453.1 - 0.19 12.2 4.9 0.076 13.5 0.6 1.9 1 1 0 2 2 2 0 FAM163 family Flu_C_NS2 PF03555.9 CCD23453.1 - 0.2 11.6 1.9 3.6 7.5 0.3 2.3 2 0 0 2 2 2 0 Influenza C non-structural protein (NS2) DUF2341 PF10102.4 CCD23453.1 - 0.8 9.8 4.7 1.6 8.9 2.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF2341) SNARE PF05739.14 CCD23454.1 - 2.7e-18 65.4 5.9 2.7e-18 65.4 4.1 2.2 3 0 0 3 3 1 1 SNARE domain Syntaxin_2 PF14523.1 CCD23454.1 - 3.9e-07 30.0 0.6 3.9e-07 30.0 0.4 3.5 2 2 0 2 2 1 1 Syntaxin-like protein TMPIT PF07851.8 CCD23454.1 - 4e-05 22.8 6.0 4e-05 22.8 4.2 1.7 2 0 0 2 2 2 1 TMPIT-like protein Synaptobrevin PF00957.16 CCD23454.1 - 7.4e-05 22.2 1.9 7.4e-05 22.2 1.3 2.0 2 0 0 2 2 2 1 Synaptobrevin MCPsignal PF00015.16 CCD23454.1 - 0.013 15.0 7.0 0.026 14.0 4.8 1.6 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.20 CCD23454.1 - 0.046 13.8 0.5 0.046 13.8 0.3 3.4 2 1 0 2 2 1 0 Syntaxin Herpes_US9 PF06072.6 CCD23454.1 - 0.057 13.2 0.3 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF912 PF06024.7 CCD23454.1 - 0.094 12.7 12.1 0.067 13.2 0.5 3.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) COG5 PF10392.4 CCD23454.1 - 0.15 12.0 0.1 0.15 12.0 0.1 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 ODV-E18 PF10717.4 CCD23454.1 - 0.26 10.7 2.9 0.39 10.1 0.1 2.4 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Seryl_tRNA_N PF02403.17 CCD23454.1 - 0.58 10.1 17.4 0.17 11.9 8.0 2.6 2 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain OppC_N PF12911.2 CCD23454.1 - 0.6 9.5 2.4 1.2 8.5 1.7 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Rho_Binding PF08912.6 CCD23454.1 - 0.61 10.4 9.4 1.7 8.9 2.8 2.9 2 0 0 2 2 2 0 Rho Binding EIIBC-GUT_N PF03612.9 CCD23454.1 - 1.3 8.5 7.0 0.48 10.0 2.8 1.7 1 1 1 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Spectrin PF00435.16 CCD23454.1 - 1.6 9.0 18.5 0.81 10.0 7.4 3.2 3 1 1 4 4 4 0 Spectrin repeat NPV_P10 PF05531.7 CCD23454.1 - 4.9 7.4 14.8 2.1 8.6 0.5 3.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 CCD23454.1 - 8.3 4.9 20.2 1.2 7.7 8.8 2.2 2 1 0 2 2 2 0 Spc7 kinetochore protein RGS PF00615.14 CCD23456.1 - 2e-07 31.1 3.5 2e-07 31.1 2.4 2.0 2 2 0 2 2 2 1 Regulator of G protein signaling domain HMGL-like PF00682.14 CCD23457.1 - 1.2e-75 254.1 0.0 1.8e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 CCD23457.1 - 1.3e-28 99.4 0.7 2.5e-28 98.4 0.5 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Syja_N PF02383.13 CCD23458.1 - 1.1e-91 306.8 1.1 2e-91 306.1 0.8 1.4 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CCD23458.1 - 2.2e-26 93.3 0.0 6.2e-26 91.8 0.0 1.8 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.11 CCD23459.1 - 9.9e-36 121.3 0.9 1.6e-35 120.6 0.6 1.4 1 0 0 1 1 1 1 YEATS family FerA PF08165.6 CCD23459.1 - 0.14 11.8 0.5 0.26 11.0 0.3 1.4 1 0 0 1 1 1 0 FerA (NUC095) domain His_Phos_1 PF00300.17 CCD23460.1 - 4e-22 78.9 0.0 1.5e-21 77.0 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.4 CCD23460.1 - 1.7e-09 36.9 0.5 6.4e-09 35.1 0.0 2.2 2 0 0 2 2 2 1 TFIIIC subunit Maf PF02545.9 CCD23461.1 - 6.1e-41 139.6 0.0 8.4e-41 139.2 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein ROK PF00480.15 CCD23461.1 - 0.031 14.0 0.1 0.046 13.5 0.1 1.2 1 0 0 1 1 1 0 ROK family HEAT PF02985.17 CCD23462.1 - 0.0018 18.1 1.0 3.6 7.9 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat HEAT_2 PF13646.1 CCD23462.1 - 0.18 12.1 0.3 0.89 9.8 0.1 2.3 2 1 1 3 3 3 0 HEAT repeats zf-H2C2_2 PF13465.1 CCD23463.1 - 2.3e-21 74.9 31.2 5.5e-09 35.8 0.7 5.3 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 CCD23463.1 - 3.8e-18 64.6 38.8 1.3e-05 25.2 0.4 6.0 6 0 0 6 6 6 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD23463.1 - 9.3e-14 50.6 29.2 0.00054 20.1 0.6 5.2 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 CCD23463.1 - 0.00037 20.5 19.9 0.0034 17.5 0.1 5.3 5 0 0 5 5 5 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCD23463.1 - 0.00082 19.4 15.5 0.057 13.5 0.1 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCD23463.1 - 0.002 17.9 25.3 0.059 13.3 1.0 4.7 5 0 0 5 5 5 3 C2H2-type zinc finger zf-Di19 PF05605.7 CCD23463.1 - 0.014 15.4 6.3 0.11 12.6 0.2 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-CHCC PF10276.4 CCD23463.1 - 0.5 10.2 7.5 4.2 7.2 0.1 3.5 3 0 0 3 3 3 0 Zinc-finger domain zf-BED PF02892.10 CCD23463.1 - 9.7 6.0 19.8 2.7 7.8 0.6 4.1 2 1 2 4 4 4 0 BED zinc finger DUF3589 PF12141.3 CCD23464.1 - 5.3e-89 298.7 0.1 2.6e-88 296.4 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) TRAPP PF04051.11 CCD23465.1 - 6.3e-31 106.9 0.0 9.1e-31 106.4 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SH3_9 PF14604.1 CCD23466.1 - 1.6e-26 91.5 0.1 1.3e-13 50.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 CCD23466.1 - 1.7e-24 85.8 0.7 1.7e-24 85.8 0.5 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 CCD23466.1 - 8.5e-24 82.6 0.0 8.7e-11 41.0 0.0 2.6 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 CCD23466.1 - 2.8e-14 52.3 0.0 3.1e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_3 PF08239.6 CCD23466.1 - 0.13 12.4 2.0 1.3 9.2 0.1 2.4 2 0 0 2 2 2 0 Bacterial SH3 domain IncA PF04156.9 CCD23466.1 - 5.1 6.6 19.3 3.9 7.0 1.7 3.3 2 1 0 3 3 3 0 IncA protein CHCH PF06747.8 CCD23467.1 - 1.4e-06 28.0 9.8 2.5e-06 27.2 6.8 1.5 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 CCD23467.1 - 3.4e-05 23.8 3.0 5.8e-05 23.1 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) COX6B PF02297.12 CCD23467.1 - 0.014 15.3 7.9 0.031 14.2 5.5 1.6 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Podoplanin PF05808.6 CCD23467.1 - 0.048 13.2 2.2 0.054 13.0 1.5 1.1 1 0 0 1 1 1 0 Podoplanin Pet191_N PF10203.4 CCD23467.1 - 0.17 11.9 3.4 0.29 11.2 2.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Pneumo_phosprot PF02478.11 CCD23467.1 - 0.98 8.8 4.6 1.2 8.6 3.2 1.1 1 0 0 1 1 1 0 Pneumovirus phosphoprotein TPR_11 PF13414.1 CCD23468.1 - 4.9e-31 106.2 28.4 7.2e-15 54.3 1.0 7.5 4 3 4 8 8 8 7 TPR repeat TPR_1 PF00515.23 CCD23468.1 - 2.4e-21 74.3 31.7 2.8e-06 26.6 1.7 9.3 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCD23468.1 - 6.6e-19 68.0 5.6 0.0026 18.3 0.0 5.8 5 1 1 6 6 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 CCD23468.1 - 4.9e-18 63.5 33.7 0.00028 20.5 0.8 10.7 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCD23468.1 - 4.5e-17 61.7 12.9 0.0002 21.2 0.1 6.6 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 CCD23468.1 - 9.2e-13 47.3 23.7 0.0025 17.8 1.2 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 CCD23468.1 - 3.4e-12 45.1 31.4 0.031 14.0 0.1 9.7 10 1 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 CCD23468.1 - 4.5e-11 42.9 13.6 0.05 13.9 0.8 5.9 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCD23468.1 - 4e-10 39.4 11.6 0.14 12.9 0.0 7.9 5 3 3 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CCD23468.1 - 2.4e-06 27.5 23.1 0.027 14.5 0.4 4.6 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CCD23468.1 - 0.0002 21.1 3.7 0.72 9.7 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCD23468.1 - 0.0053 16.4 19.0 0.11 12.3 0.0 6.7 8 0 0 8 8 8 1 Tetratricopeptide repeat NARP1 PF12569.3 CCD23468.1 - 0.022 13.5 0.1 0.022 13.5 0.1 4.4 2 2 2 5 5 5 0 NMDA receptor-regulated protein 1 Presenilin PF01080.12 CCD23468.1 - 1.8 7.3 4.1 2.8 6.6 2.9 1.2 1 0 0 1 1 1 0 Presenilin TPR_6 PF13174.1 CCD23468.1 - 5 7.8 17.1 9.8 6.8 0.1 6.9 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_20 PF14561.1 CCD23468.1 - 5.1 7.2 9.8 2.3 8.4 0.6 3.7 4 1 0 4 4 2 0 Tetratricopeptide repeat ORC6 PF05460.8 CCD23469.1 - 3.2e-90 302.7 1.9 4.2e-90 302.3 1.3 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) CDC45 PF02724.9 CCD23469.1 - 1.9 6.4 7.0 2.7 5.8 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein N-SET PF11764.3 CCD23470.1 - 4.5e-40 137.2 1.0 4.5e-40 137.2 0.7 2.7 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 CCD23470.1 - 1.7e-24 86.9 1.2 8.4e-24 84.7 0.2 2.8 2 1 0 2 2 2 1 SET domain SET_assoc PF11767.3 CCD23470.1 - 8.1e-21 73.1 0.4 2.2e-20 71.7 0.3 1.8 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated MutS_V PF00488.16 CCD23471.1 - 4.6e-75 252.0 0.0 8.2e-75 251.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCD23471.1 - 9.5e-32 110.4 1.8 2e-31 109.3 1.2 1.6 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CCD23471.1 - 2.5e-25 88.7 0.0 1.1e-24 86.5 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_II PF05188.12 CCD23471.1 - 1e-08 35.3 0.2 5.3e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 MutS domain II DUF59 PF01883.14 CCD23472.1 - 0.00016 21.6 0.0 0.00043 20.2 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function DUF59 CDP-OH_P_transf PF01066.16 CCD23473.1 - 7.1e-17 61.5 1.2 7.1e-17 61.5 0.8 2.8 2 1 2 4 4 4 1 CDP-alcohol phosphatidyltransferase NDT80_PhoG PF05224.7 CCD23474.1 - 3e-64 216.4 0.2 1e-63 214.6 0.2 1.9 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family DUF3605 PF12239.3 CCD23475.1 - 8.5e-39 132.9 7.1 1.3e-38 132.3 4.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) DSRB PF10781.4 CCD23475.1 - 0.11 12.0 0.1 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Dextransucrase DSRB PIR PF00399.14 CCD23476.1 - 0.029 13.7 0.6 0.065 12.6 0.4 1.6 1 0 0 1 1 1 0 Yeast PIR protein repeat Sas10_Utp3 PF04000.10 CCD23477.1 - 0.031 14.4 0.0 0.094 12.9 0.0 1.8 1 1 0 1 1 1 0 Sas10/Utp3/C1D family RRM_6 PF14259.1 CCD23477.1 - 0.1 12.6 0.0 0.68 9.9 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CAP_GLY PF01302.20 CCD23478.1 - 2.2e-20 72.1 0.1 4.2e-20 71.2 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 CCD23478.1 - 3.9e-06 27.0 0.0 8.6e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUF3052 PF11253.3 CCD23478.1 - 0.13 11.8 0.2 0.21 11.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3052) LSM PF01423.17 CCD23479.1 - 1.5e-16 59.7 0.1 2e-16 59.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCD23479.1 - 0.17 11.8 0.5 0.53 10.2 0.0 1.9 2 0 0 2 2 2 0 Ataxin 2 SM domain UPRTase PF14681.1 CCD23480.1 - 4.1e-76 254.8 0.0 5.1e-76 254.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CCD23480.1 - 0.0036 17.0 0.0 0.0058 16.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 CCD23480.1 - 0.066 12.9 0.2 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.14 CCD23481.1 - 8.9e-111 370.0 0.0 1.2e-110 369.6 0.0 1.0 1 0 0 1 1 1 1 Actin Tub_2 PF04525.7 CCD23482.1 - 0.094 12.1 0.0 0.094 12.1 0.0 1.0 1 0 0 1 1 1 0 Tubby C 2 DUF2457 PF10446.4 CCD23483.1 - 0.0025 16.6 22.5 0.0025 16.6 15.6 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF2457) Peptidase_M14 PF00246.19 CCD23484.1 - 5.5e-65 219.7 0.2 7.5e-65 219.3 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Endosulfine PF04667.12 CCD23485.1 - 1.7e-30 104.8 0.0 2.8e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region INSIG PF07281.7 CCD23486.1 - 4.1e-12 45.8 2.0 7.4e-12 45.0 1.4 1.5 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) ATP1G1_PLM_MAT8 PF02038.11 CCD23486.1 - 7 5.7 6.3 0.93 8.5 0.0 2.5 2 1 1 3 3 3 0 ATP1G1/PLM/MAT8 family WLM PF08325.5 CCD23487.1 - 4.2e-52 176.7 0.0 6.7e-52 176.0 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 CCD23487.1 - 0.082 12.6 0.1 0.19 11.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF45 Pkinase PF00069.20 CCD23488.1 - 1.1e-33 116.5 0.0 2.2e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23488.1 - 2.9e-12 46.2 0.0 5.4e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCD23488.1 - 0.011 15.4 0.1 0.2 11.3 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Aminotran_1_2 PF00155.16 CCD23490.1 - 2.7e-13 49.6 0.0 7.4e-13 48.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCD23490.1 - 0.086 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Kin17_mid PF10357.4 CCD23491.1 - 0.00089 18.8 0.3 0.00095 18.8 0.2 1.1 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein Inhibitor_I9 PF05922.11 CCD23491.1 - 0.017 15.6 0.1 0.049 14.1 0.1 1.9 1 1 0 1 1 1 0 Peptidase inhibitor I9 DUF3198 PF11433.3 CCD23491.1 - 0.084 12.7 0.1 0.6 10.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3198) DUF3081 PF11280.3 CCD23491.1 - 0.11 12.0 0.2 0.12 11.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3081) CENP-F_N PF10481.4 CCD23491.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.0 1 0 0 1 1 1 0 Cenp-F N-terminal domain RRM_1 PF00076.17 CCD23492.1 - 1.7e-25 88.4 3.5 2.9e-13 49.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD23492.1 - 1.5e-14 53.7 1.1 1.1e-05 25.2 0.0 3.6 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD23492.1 - 1.3e-10 40.9 3.5 1.3e-06 28.1 1.0 3.6 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCD23492.1 - 0.0014 18.4 0.3 0.69 9.7 0.0 3.4 3 1 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 CCD23492.1 - 0.065 13.0 0.2 1.3 8.8 0.1 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CCD23492.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Limkain b1 DUF500 PF04366.7 CCD23493.1 - 1.1e-43 147.6 0.1 1.9e-43 146.8 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CCD23493.1 - 9.2e-18 63.3 0.0 1.8e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCD23493.1 - 2.1e-15 56.0 0.1 3.6e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCD23493.1 - 6.3e-13 48.0 0.0 1.1e-12 47.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Herpes_LMP2 PF07415.6 CCD23493.1 - 5.9 5.3 4.9 9 4.7 3.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein PHP PF02811.14 CCD23494.1 - 1.8e-18 66.9 0.4 4.8e-18 65.5 0.3 1.6 1 1 0 1 1 1 1 PHP domain GST_C PF00043.20 CCD23494.1 - 0.11 12.5 0.0 4.7 7.2 0.0 2.5 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Acetyltransf_13 PF13880.1 CCD23495.1 - 8.7e-20 70.2 0.0 1.6e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 CCD23495.1 - 1.1e-09 37.6 0.3 2.1e-09 36.8 0.2 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO DSPn PF14671.1 CCD23496.1 - 1.2e-50 171.1 0.1 3.1e-50 169.8 0.0 1.7 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CCD23496.1 - 3.4e-24 84.9 0.0 1.9e-22 79.2 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCD23496.1 - 0.00019 20.8 0.0 0.00036 19.9 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 CCD23496.1 - 0.0005 19.5 0.7 0.00086 18.7 0.1 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 CCD23496.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CCD23496.1 - 0.08 13.1 0.1 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family zf-RING_UBOX PF13445.1 CCD23497.1 - 0.012 15.3 0.1 0.046 13.4 0.0 2.1 1 0 0 1 1 1 0 RING-type zinc-finger WD40 PF00400.27 CCD23497.1 - 0.19 11.6 1.7 3.9 7.5 0.1 3.4 4 0 0 4 4 4 0 WD domain, G-beta repeat COMPASS-Shg1 PF05205.7 CCD23498.1 - 7.1e-23 80.9 3.9 9.2e-23 80.5 2.7 1.2 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 Alpha_L_fucos PF01120.12 CCD23498.1 - 0.048 12.5 1.1 0.053 12.4 0.8 1.0 1 0 0 1 1 1 0 Alpha-L-fucosidase EFG_IV PF03764.13 CCD23498.1 - 0.16 11.5 0.2 0.25 10.9 0.2 1.2 1 0 0 1 1 1 0 Elongation factor G, domain IV DUF3333 PF11812.3 CCD23498.1 - 0.19 11.7 1.0 0.29 11.1 0.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3333) RhoGAP PF00620.22 CCD23499.1 - 6e-42 142.8 0.2 1.2e-40 138.5 0.0 2.6 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 CCD23499.1 - 2.3e-12 46.9 6.1 4.9e-12 45.8 0.4 2.9 1 1 1 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Methyltransf_PK PF05891.7 CCD23500.1 - 3.9e-95 317.2 0.0 4.5e-95 317.0 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 CCD23500.1 - 2.6e-08 33.7 0.0 3.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCD23500.1 - 6.7e-06 26.5 0.0 1.2e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD23500.1 - 3e-05 24.5 0.0 5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD23500.1 - 0.00038 20.7 0.0 0.00065 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCD23500.1 - 0.0092 16.4 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CCD23500.1 - 0.013 14.7 0.0 0.03 13.4 0.0 1.7 1 1 0 1 1 1 0 O-methyltransferase Arb1 PF09692.5 CCD23500.1 - 0.027 13.3 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Argonaute siRNA chaperone (ARC) complex subunit Arb1 CMAS PF02353.15 CCD23500.1 - 0.051 12.6 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Bin3 PF06859.7 CCD23500.1 - 0.099 12.6 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) DUF2481 PF10654.4 CCD23501.1 - 0.0051 16.5 2.7 0.0077 15.9 1.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2481) WHEP-TRS PF00458.15 CCD23501.1 - 0.023 14.3 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 WHEP-TRS domain DUF2951 PF11166.3 CCD23501.1 - 0.32 10.8 4.5 0.12 12.2 1.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) SHMT PF00464.14 CCD23502.1 - 3.5e-204 677.6 0.0 4.2e-204 677.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CCD23502.1 - 0.084 12.0 0.0 0.24 10.5 0.0 1.4 1 1 0 1 1 1 0 Beta-eliminating lyase Ras PF00071.17 CCD23503.1 - 1.9e-39 134.6 0.4 2.6e-39 134.1 0.3 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD23503.1 - 1.9e-18 67.1 0.4 2.9e-18 66.4 0.2 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCD23503.1 - 6.6e-17 61.2 0.3 1e-16 60.6 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCD23503.1 - 1.9e-09 37.4 0.2 3.5e-09 36.6 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCD23503.1 - 2.2e-09 36.8 0.0 3e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCD23503.1 - 1.1e-08 34.6 0.3 5.2e-08 32.5 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CCD23503.1 - 2.8e-06 26.6 0.2 3.9e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 CCD23503.1 - 0.00016 20.9 0.5 0.21 10.8 0.0 2.7 1 1 2 3 3 3 2 Ferrous iron transport protein B AAA_15 PF13175.1 CCD23503.1 - 0.0012 18.0 1.6 0.0016 17.5 1.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.4 CCD23503.1 - 0.01 15.3 1.6 1.7 8.0 1.1 2.9 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 CCD23503.1 - 0.059 12.5 0.9 0.26 10.4 0.4 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Septin PF00735.13 CCD23503.1 - 0.065 12.2 0.8 0.11 11.4 0.1 1.6 2 0 0 2 2 2 0 Septin Ins_allergen_rp PF06757.8 CCD23503.1 - 0.088 12.2 0.0 0.15 11.5 0.0 1.4 1 1 0 1 1 1 0 Insect allergen related repeat, nitrile-specifier detoxification AAA_22 PF13401.1 CCD23503.1 - 0.1 12.7 0.1 0.24 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CCD23503.1 - 0.11 12.7 0.5 0.36 11.0 0.3 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rif1_N PF12231.3 CCD23504.1 - 3.1e-44 151.4 13.4 6.4e-44 150.4 9.3 1.5 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Pkinase PF00069.20 CCD23505.1 - 1.1e-61 208.2 0.0 1.4e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23505.1 - 7.7e-35 120.2 0.0 1e-34 119.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD23505.1 - 2e-09 36.8 0.0 3.7e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CCD23505.1 - 0.0087 14.9 0.0 0.021 13.6 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 Kdo PF06293.9 CCD23505.1 - 0.062 12.3 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CCD23505.1 - 0.079 12.5 1.4 0.2 11.1 0.0 2.2 2 1 0 2 2 2 0 Choline/ethanolamine kinase UBX PF00789.15 CCD23506.1 - 7.8e-18 64.3 0.1 1.6e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain Methyltransf_16 PF10294.4 CCD23508.1 - 6.9e-22 77.7 0.5 1.1e-21 77.0 0.1 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.1 CCD23508.1 - 9.7e-07 28.4 0.0 2.5e-06 27.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD23508.1 - 4.3e-05 24.0 0.0 8.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCD23508.1 - 0.00014 21.2 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CCD23508.1 - 0.00033 20.3 0.0 0.00067 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCD23508.1 - 0.0022 18.0 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCD23508.1 - 0.043 14.2 0.0 0.084 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CCD23508.1 - 0.1 13.1 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain HbrB PF08539.6 CCD23509.1 - 1.1e-31 109.8 1.5 2e-31 108.9 1.0 1.5 1 0 0 1 1 1 1 HbrB-like DUF1674 PF07896.7 CCD23510.1 - 1.2e-15 57.4 3.8 2.4e-15 56.4 2.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Ribosomal_L37 PF08561.5 CCD23511.1 - 4.5e-25 87.0 0.3 5.6e-25 86.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 zf-C2H2_2 PF12756.2 CCD23512.1 - 2.1e-35 120.8 6.7 7.1e-33 112.7 2.3 2.8 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CCD23512.1 - 0.0058 16.7 3.5 0.38 10.9 0.3 3.0 2 1 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CCD23512.1 - 7.1 7.2 6.8 36 5.0 0.0 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger adh_short PF00106.20 CCD23513.1 - 2.8e-19 69.6 0.0 9.6e-18 64.6 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCD23513.1 - 3.1e-10 40.0 0.0 6.6e-10 38.9 0.0 1.4 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CCD23513.1 - 0.002 17.0 0.1 0.003 16.4 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Coiled-coil_56 PF09813.4 CCD23514.1 - 0.15 12.0 0.8 0.23 11.4 0.1 1.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 56 Ribosomal_L17 PF01196.14 CCD23515.1 - 2.2e-27 95.4 0.1 5.5e-27 94.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L17 YqgF PF14639.1 CCD23515.1 - 0.0058 16.2 0.7 3.4 7.2 0.0 2.4 2 0 0 2 2 2 2 Holliday-junction resolvase-like of SPT6 zf-DNL PF05180.7 CCD23515.1 - 0.12 12.1 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 0 DNL zinc finger DSPc PF00782.15 CCD23516.1 - 5.9e-26 90.6 0.1 4.5e-21 74.8 0.1 3.9 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCD23516.1 - 8.9e-07 28.4 0.0 2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 CCD23516.1 - 0.00045 19.6 0.4 0.0032 16.9 0.1 2.3 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 CCD23516.1 - 0.11 12.5 0.0 0.31 11.0 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate CBFD_NFYB_HMF PF00808.18 CCD23517.1 - 0.0019 18.2 1.4 0.0024 17.8 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Paf1 PF03985.8 CCD23518.1 - 1.4e-146 488.6 26.0 1.6e-146 488.4 18.0 1.0 1 0 0 1 1 1 1 Paf1 RNA_polI_A34 PF08208.6 CCD23518.1 - 6.7e-05 22.6 3.6 6.7e-05 22.6 2.5 2.1 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 UBN2 PF14223.1 CCD23520.1 - 0.095 12.4 0.1 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_4 PF14392.1 CCD23520.1 - 0.29 10.8 1.9 0.56 9.9 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle PAT1 PF09770.4 CCD23520.1 - 6.4 4.8 11.0 8.4 4.4 7.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RCC1_2 PF13540.1 CCD23521.1 - 1.6e-15 56.1 2.0 2.9e-05 23.5 0.1 5.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CCD23521.1 - 1.7e-13 50.5 0.1 0.00013 22.0 0.3 5.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 CCD23521.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 F-box-like Hira PF07569.6 CCD23521.1 - 0.065 12.4 0.0 0.13 11.4 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split Peptidase_M20 PF01546.23 CCD23522.1 - 1.6e-23 83.1 0.0 3e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCD23522.1 - 8.6e-13 48.0 0.0 1.7e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.27 CCD23522.1 - 1.2e-09 37.6 9.6 0.0019 18.0 0.1 6.1 5 1 0 5 5 5 4 WD domain, G-beta repeat MRP-L27 PF09809.4 CCD23523.1 - 8.1e-31 105.9 1.2 1.3e-30 105.3 0.8 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SecY PF00344.15 CCD23524.1 - 1.7e-52 178.4 22.4 2.5e-52 177.9 15.6 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CCD23524.1 - 8.8e-08 31.5 3.6 1.2e-07 31.0 0.1 2.5 2 0 0 2 2 2 1 Plug domain of Sec61p DUF792 PF05632.6 CCD23524.1 - 0.0047 16.3 0.2 0.0093 15.3 0.2 1.4 1 0 0 1 1 1 1 Borrelia burgdorferi protein of unknown function (DUF792) DUF3215 PF11503.3 CCD23524.1 - 0.092 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) A_deaminase PF00962.17 CCD23525.1 - 1.6e-17 63.4 0.0 2e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 Adenosine/AMP deaminase Peptidase_M28 PF04389.12 CCD23526.1 - 9.8e-36 123.1 0.0 1.9e-35 122.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CCD23526.1 - 1.8e-10 40.3 0.0 3.9e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 CCD23526.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 CCD23526.1 - 0.0017 17.1 0.0 0.0036 16.1 0.0 1.5 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Mem_trans PF03547.13 CCD23527.1 - 6.4e-63 212.3 14.2 1.7e-62 210.9 9.8 1.6 1 1 0 1 1 1 1 Membrane transport protein CcoS PF03597.10 CCD23527.1 - 0.67 9.4 6.9 5.1 6.6 0.8 3.3 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF2542 PF10808.3 CCD23527.1 - 0.7 10.1 3.5 0.78 10.0 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2542) Cytokin_check_N PF10407.4 CCD23528.1 - 1.4e-29 101.5 1.3 3.2e-29 100.3 0.9 1.7 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus CAP PF00188.21 CCD23530.1 - 6.2e-21 75.1 6.0 1.1e-20 74.3 3.7 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family TFIIA PF03153.8 CCD23530.1 - 1.9 8.3 9.0 2.3 8.0 6.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_BLLF1 PF05109.8 CCD23530.1 - 2.4 6.0 38.7 3 5.7 26.8 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Ras PF00071.17 CCD23531.1 - 4.4e-55 185.4 1.1 5.3e-55 185.2 0.8 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD23531.1 - 5.3e-22 78.5 0.2 1e-21 77.6 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCD23531.1 - 4.6e-14 52.0 0.4 6.6e-14 51.5 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCD23531.1 - 2e-07 30.6 0.2 4.2e-07 29.5 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCD23531.1 - 2.1e-06 27.0 0.1 2.6e-06 26.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCD23531.1 - 1.3e-05 25.0 0.0 2.7e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 CCD23531.1 - 0.021 13.8 0.1 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Septin DUF258 PF03193.11 CCD23531.1 - 0.1 11.8 0.2 0.15 11.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCD23531.1 - 0.11 12.4 0.2 0.31 11.0 0.0 1.6 2 1 0 2 2 2 0 AAA ATPase domain DUF4287 PF14117.1 CCD23531.1 - 0.14 11.8 0.1 1.6 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) Mitofilin PF09731.4 CCD23532.1 - 1.2e-92 311.5 26.5 1.1e-85 288.5 18.1 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein DUF1104 PF06518.6 CCD23532.1 - 0.031 14.4 9.5 0.041 14.0 3.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1104) IBR PF01485.16 CCD23533.1 - 3.2e-17 62.1 39.8 1.9e-09 37.2 2.7 3.8 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 CCD23533.1 - 1.9e-05 24.2 12.5 1.9e-05 24.2 8.7 4.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD23533.1 - 0.0028 17.6 11.4 0.0028 17.6 7.9 5.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Bd3614_N PF14442.1 CCD23533.1 - 0.25 11.3 2.6 0.47 10.4 1.8 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal CENP-B_dimeris PF09026.5 CCD23533.1 - 4.3 7.6 10.4 0.054 13.7 1.3 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain DUF3808 PF10300.4 CCD23534.1 - 3e-168 560.2 3.9 3.7e-168 559.9 2.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 CCD23534.1 - 0.0013 19.2 0.2 0.59 10.8 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat HARE-HTH PF05066.8 CCD23534.1 - 0.0055 17.0 0.2 0.057 13.7 0.1 2.5 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain TPR_2 PF07719.12 CCD23534.1 - 0.017 14.9 0.1 22 5.2 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_4 PF12763.2 CCD23535.1 - 0.01 15.5 0.2 0.043 13.5 0.1 2.1 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 CCD23535.1 - 0.059 12.7 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 EF hand Vps51 PF08700.6 CCD23536.1 - 1.2e-09 37.8 0.4 1.2e-09 37.8 0.3 2.1 3 0 0 3 3 3 1 Vps51/Vps67 Arrestin_C PF02752.17 CCD23537.1 - 2e-14 53.8 0.1 2e-14 53.8 0.0 5.9 4 1 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCD23537.1 - 7.4e-09 35.5 11.7 1.2e-07 31.6 0.3 3.7 4 0 0 4 4 4 2 Arrestin (or S-antigen), N-terminal domain NTR2 PF15458.1 CCD23538.1 - 1.2e-44 152.4 22.8 1.2e-44 152.4 15.8 1.9 2 0 0 2 2 2 1 Nineteen complex-related protein 2 SAPS PF04499.10 CCD23539.1 - 1.5e-167 558.0 9.7 1.5e-167 558.0 6.7 3.7 3 1 0 3 3 3 2 SIT4 phosphatase-associated protein ChAPs PF09295.5 CCD23540.1 - 6.4e-44 150.2 10.7 3.6e-34 118.2 5.1 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 CCD23540.1 - 0.00011 21.7 0.9 0.0003 20.3 0.6 1.7 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 CCD23540.1 - 0.00016 21.0 0.9 0.00043 19.7 0.6 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCD23540.1 - 0.00027 21.2 0.0 0.00056 20.1 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCD23540.1 - 0.0078 16.0 0.2 0.042 13.7 0.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCD23540.1 - 0.014 15.2 0.0 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCD23540.1 - 0.015 15.4 0.2 0.084 13.1 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCD23540.1 - 0.024 14.3 0.5 0.13 12.1 0.3 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 CCD23540.1 - 0.027 14.5 3.1 0.1 12.7 2.1 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CCD23540.1 - 0.032 14.1 0.1 0.079 12.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat PmrD PF11183.3 CCD23540.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD TPR_16 PF13432.1 CCD23540.1 - 0.24 12.1 0.0 0.47 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat UPF0118 PF01594.11 CCD23540.1 - 4.1 6.2 4.7 9.5 5.1 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF20 GCS PF03074.11 CCD23541.1 - 2.4e-145 484.2 0.5 3e-145 483.9 0.3 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase Rep_Org_C PF06926.6 CCD23541.1 - 0.027 14.5 1.3 12 6.0 0.0 3.1 2 1 1 3 3 3 0 Putative replisome organiser protein C-terminus IF-2B PF01008.12 CCD23542.1 - 1.7e-75 253.5 0.0 2e-75 253.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 CCD23542.1 - 0.059 13.0 0.1 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 DeoR C terminal sensor domain Sin_N PF04801.8 CCD23543.1 - 1.6e-18 66.7 1.7 3.5e-18 65.6 1.2 1.5 1 1 0 1 1 1 1 Sin-like protein conserved region Imm23 PF15593.1 CCD23543.1 - 0.16 12.2 3.3 9.4 6.4 0.0 2.8 2 1 0 3 3 3 0 Immunity protein 23 PGA2 PF07543.7 CCD23543.1 - 3.2 7.5 10.4 0.051 13.3 0.5 2.5 3 0 0 3 3 3 0 Protein trafficking PGA2 DEAD PF00270.24 CCD23544.1 - 2.1e-37 128.2 0.0 4.4e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD23544.1 - 2.9e-18 65.4 0.0 6.3e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCD23544.1 - 3.7e-17 61.6 0.0 8.5e-17 60.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CCD23544.1 - 2.7e-06 27.3 0.0 2.7e-06 27.3 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C2HC5 PF06221.8 CCD23545.1 - 1.9e-20 72.3 5.9 3.4e-20 71.5 4.1 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.1 CCD23545.1 - 0.13 11.5 3.6 0.25 10.6 2.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF3292 PF11696.3 CCD23545.1 - 0.71 7.6 7.3 1.2 6.9 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) PHD PF00628.24 CCD23546.1 - 7.4e-09 35.1 8.3 1.7e-08 34.0 5.7 1.7 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 CCD23546.1 - 7.5e-08 32.8 1.6 1.5e-07 31.8 0.0 2.2 2 1 0 2 2 2 1 SET domain PHD_2 PF13831.1 CCD23546.1 - 0.013 14.7 3.7 0.028 13.7 2.6 1.5 1 0 0 1 1 1 0 PHD-finger UNC-50 PF05216.8 CCD23547.1 - 2.9e-90 301.5 19.8 3.4e-90 301.2 13.7 1.0 1 0 0 1 1 1 1 UNC-50 family PLDc PF00614.17 CCD23548.1 - 1.3e-17 62.9 1.3 4.5e-09 35.8 0.3 3.0 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CCD23548.1 - 7.4e-11 41.8 0.2 4.7e-08 32.8 0.0 3.2 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 CCD23548.1 - 7e-05 22.5 1.5 0.096 12.4 0.1 4.0 3 0 0 3 3 3 2 PX domain GATA PF00320.22 CCD23549.1 - 1.8e-14 52.7 2.0 4.4e-14 51.5 1.4 1.7 1 0 0 1 1 1 1 GATA zinc finger Snf7 PF03357.16 CCD23550.1 - 2.9e-15 56.0 21.1 2.9e-15 56.0 14.6 1.4 1 1 0 1 1 1 1 Snf7 GrpE PF01025.14 CCD23550.1 - 0.32 10.5 12.5 0.013 15.0 4.5 1.6 2 0 0 2 2 2 0 GrpE DUF501 PF04417.7 CCD23550.1 - 0.34 10.7 3.0 0.58 10.0 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF501) DUF948 PF06103.6 CCD23550.1 - 0.94 9.3 6.3 0.96 9.3 0.5 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF3385 PF11865.3 CCD23550.1 - 2.4 8.0 5.5 10 6.0 1.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) Cpn60_TCP1 PF00118.19 CCD23551.1 - 7.4e-147 489.8 4.6 8.6e-147 489.6 3.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MtlR PF05068.7 CCD23551.1 - 0.034 13.5 0.3 0.063 12.7 0.2 1.4 1 0 0 1 1 1 0 Mannitol repressor WD40 PF00400.27 CCD23552.1 - 2.5e-39 131.7 9.9 1.4e-08 34.2 0.0 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat DASH_Spc34 PF08657.5 CCD23553.1 - 2.1e-62 211.1 11.6 2.4e-62 210.9 8.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 DRIM PF07539.7 CCD23553.1 - 0.042 13.2 2.1 0.049 13.0 0.0 2.1 2 0 0 2 2 2 0 Down-regulated in metastasis Ead_Ea22 PF13935.1 CCD23553.1 - 0.062 13.6 3.3 0.066 13.5 1.3 1.8 2 0 0 2 2 2 0 Ead/Ea22-like protein Peptidase_M22 PF00814.20 CCD23554.1 - 4.3e-83 278.8 0.0 5.3e-83 278.5 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 CCD23554.1 - 0.018 14.1 0.0 0.023 13.8 0.0 1.1 1 0 0 1 1 1 0 Carbamoyltransferase AA_permease PF00324.16 CCD23555.1 - 7e-144 479.7 40.4 8e-144 479.5 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD23555.1 - 1.3e-37 129.3 41.8 1.7e-37 128.9 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease SUN PF03856.8 CCD23557.1 - 2.4e-104 348.0 18.6 2.4e-104 348.0 12.9 1.6 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) UEV PF05743.8 CCD23557.1 - 0.026 14.2 0.0 0.051 13.2 0.0 1.5 1 0 0 1 1 1 0 UEV domain MSP1_C PF07462.6 CCD23557.1 - 3 6.1 5.4 4.1 5.6 3.7 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus His_Phos_1 PF00300.17 CCD23558.1 - 2.6e-28 99.0 0.1 3.4e-28 98.7 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 CCD23558.1 - 0.015 14.6 0.0 0.022 14.0 0.0 1.2 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 2) GP41 PF00517.12 CCD23559.1 - 0.2 11.1 3.6 0.19 11.2 0.3 2.1 2 0 0 2 2 2 0 Retroviral envelope protein NAP PF00956.13 CCD23562.1 - 6.1e-77 258.0 13.8 6.1e-77 258.0 9.5 2.2 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) DUF2422 PF10337.4 CCD23563.1 - 4.2e-44 151.0 1.6 4.2e-44 151.0 1.1 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CCD23563.1 - 8.4e-12 45.1 14.8 8.4e-12 45.1 10.2 3.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 CCD23563.1 - 4.4e-06 26.4 0.3 1e-05 25.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 CCD23563.1 - 6.9e-05 21.6 18.6 6.9e-05 21.6 4.5 2.8 2 1 0 2 2 2 2 Aluminium activated malate transporter UFD1 PF03152.9 CCD23564.1 - 2e-74 248.4 0.0 2.7e-74 248.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 TPR_11 PF13414.1 CCD23565.1 - 1.4e-12 47.0 19.2 6.1e-05 22.5 0.4 7.1 5 2 1 8 8 8 4 TPR repeat TPR_2 PF07719.12 CCD23565.1 - 2.4e-11 42.6 20.6 0.12 12.3 0.0 9.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCD23565.1 - 5.4e-11 41.7 7.9 0.026 14.6 0.2 7.1 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCD23565.1 - 1.5e-10 41.4 10.2 0.0057 17.3 0.3 6.1 5 1 2 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 CCD23565.1 - 2.2e-10 39.6 14.2 0.06 12.9 0.1 8.3 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCD23565.1 - 2.4e-10 40.1 18.8 8.3e-06 25.6 0.2 6.3 4 1 2 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCD23565.1 - 3e-10 40.3 9.1 0.0042 17.4 0.2 5.9 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCD23565.1 - 1.6e-08 34.4 0.9 4 8.3 0.0 6.8 5 1 1 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 CCD23565.1 - 1.2e-07 31.7 19.6 0.0089 16.1 0.2 5.9 5 1 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCD23565.1 - 6e-06 26.3 14.1 0.41 11.2 0.0 7.2 9 0 0 9 9 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCD23565.1 - 0.00023 20.7 20.6 0.0038 16.9 0.0 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCD23565.1 - 0.00062 19.5 0.3 8.3 6.3 0.0 4.6 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 CCD23565.1 - 0.028 14.5 3.6 2.3 8.4 0.0 4.0 4 1 1 5 5 4 0 Tetratricopeptide repeat Pox_polyA_pol_N PF12630.2 CCD23565.1 - 0.13 12.3 0.0 0.13 12.3 0.0 3.3 3 0 0 3 3 3 0 Poxvirus poly(A) polymerase N-terminal domain TPR_7 PF13176.1 CCD23565.1 - 0.89 9.5 11.8 46 4.1 0.1 6.1 5 2 1 6 6 6 0 Tetratricopeptide repeat Tankyrase_bdg_C PF15327.1 CCD23565.1 - 1 9.5 4.8 0.66 10.1 0.3 2.3 2 0 0 2 2 2 0 Tankyrase binding protein C terminal domain DUF1687 PF07955.6 CCD23566.1 - 1.1e-29 103.0 0.2 1.3e-29 102.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) LSM PF01423.17 CCD23567.1 - 4.9e-14 51.6 0.1 1e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 LSM domain EcoRI_methylase PF13651.1 CCD23567.1 - 0.037 13.1 0.0 0.037 13.1 0.0 2.0 1 1 1 2 2 2 0 Adenine-specific methyltransferase EcoRI Peptidase_S49_N PF08496.5 CCD23567.1 - 0.11 12.2 7.9 0.12 12.1 1.7 2.1 2 0 0 2 2 2 0 Peptidase family S49 N-terminal TrkH PF02386.11 CCD23569.1 - 4.4e-128 426.7 7.2 8.6e-127 422.5 1.1 2.5 2 1 0 2 2 2 2 Cation transport protein Podoplanin PF05808.6 CCD23569.1 - 4 6.9 5.5 11 5.6 3.8 1.6 1 0 0 1 1 1 0 Podoplanin Solute_trans_a PF03619.11 CCD23570.1 - 1.1e-79 267.5 12.1 1.4e-79 267.2 8.4 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Mito_carr PF00153.22 CCD23571.1 - 2e-64 213.3 0.8 1.3e-21 76.0 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein DHC_N2 PF08393.8 CCD23572.1 - 3.2e-86 289.3 9.8 3.2e-86 289.3 6.8 4.9 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 CCD23572.1 - 9.9e-84 281.7 30.0 9.9e-84 281.7 20.8 5.4 6 0 0 6 6 6 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 CCD23572.1 - 1.2e-55 188.6 0.0 2.3e-55 187.6 0.0 1.5 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 Dynein_heavy PF03028.10 CCD23572.1 - 6.2e-33 113.7 0.0 6.2e-33 113.7 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain and region D6 of dynein motor AAA_8 PF12780.2 CCD23572.1 - 7.2e-27 94.0 0.1 2.4e-26 92.2 0.1 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.2 CCD23572.1 - 3.6e-26 91.4 2.0 1.2e-25 89.7 0.7 2.4 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CCD23572.1 - 1.6e-22 79.7 0.3 1.2e-08 34.7 0.0 5.1 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) MT PF12777.2 CCD23572.1 - 1.4e-21 76.6 3.5 3e-21 75.5 2.4 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_22 PF13401.1 CCD23572.1 - 9.9e-12 45.1 6.9 0.00023 21.3 0.0 6.6 7 0 0 7 7 4 2 AAA domain AAA PF00004.24 CCD23572.1 - 2.8e-10 40.5 0.0 0.006 16.7 0.0 4.6 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCD23572.1 - 2.1e-09 37.6 0.3 0.032 14.1 0.0 4.5 4 0 0 4 4 3 2 AAA ATPase domain Zeta_toxin PF06414.7 CCD23572.1 - 7.2e-06 25.2 0.0 0.004 16.2 0.0 3.7 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.1 CCD23572.1 - 2.4e-05 24.2 0.1 0.13 12.1 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA_17 PF13207.1 CCD23572.1 - 9e-05 23.2 3.7 0.6 10.9 0.0 5.6 5 0 0 5 5 4 1 AAA domain RNA_helicase PF00910.17 CCD23572.1 - 0.00014 21.9 0.1 4 7.6 0.0 4.2 3 0 0 3 3 3 1 RNA helicase IstB_IS21 PF01695.12 CCD23572.1 - 0.00056 19.3 0.1 0.51 9.7 0.0 3.8 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_30 PF13604.1 CCD23572.1 - 0.00066 19.3 0.0 12 5.3 0.1 4.0 4 0 0 4 4 4 0 AAA domain DUF258 PF03193.11 CCD23572.1 - 0.001 18.2 1.4 0.19 10.9 0.0 3.4 4 0 0 4 4 3 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCD23572.1 - 0.0031 17.8 15.0 0.26 11.5 0.0 6.0 6 0 0 6 6 4 1 AAA domain AAA_19 PF13245.1 CCD23572.1 - 0.013 15.2 0.4 1.2 8.9 0.0 3.0 3 0 0 3 3 3 0 Part of AAA domain AAA_29 PF13555.1 CCD23572.1 - 0.013 14.9 0.1 1.6 8.3 0.0 3.1 3 0 0 3 3 2 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 CCD23572.1 - 0.021 14.0 0.2 1.1 8.4 0.0 3.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 CCD23572.1 - 0.027 13.9 0.1 0.85 9.0 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 CCD23572.1 - 0.074 13.3 8.4 0.78 10.0 0.0 4.5 4 0 0 4 4 3 0 ABC transporter AAA_28 PF13521.1 CCD23572.1 - 0.094 12.6 1.1 28 4.6 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_25 PF13481.1 CCD23572.1 - 0.097 12.0 0.3 3.5 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 CCD23572.1 - 0.42 10.0 9.4 0.79 9.0 0.1 5.3 6 0 0 6 6 5 0 AAA-like domain Ras PF00071.17 CCD23573.1 - 3.3e-50 169.6 0.0 4.6e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD23573.1 - 8.9e-18 64.9 0.0 1.9e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCD23573.1 - 1.8e-08 33.8 0.0 2.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCD23573.1 - 0.0013 18.6 0.0 0.0029 17.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCD23573.1 - 0.008 15.3 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region tRNA_U5-meth_tr PF05958.6 CCD23574.1 - 5.2e-23 81.3 0.5 6.7e-22 77.6 0.3 2.2 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.15 CCD23574.1 - 9.7e-12 44.5 0.1 2e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.1 CCD23574.1 - 6.4e-11 42.0 0.1 1.5e-10 40.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD23574.1 - 6.3e-06 26.7 0.0 1.5e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CCD23574.1 - 1.2e-05 24.9 0.0 2.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.8 CCD23574.1 - 1.9e-05 23.9 0.0 3.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.10 CCD23574.1 - 3.2e-05 23.4 0.0 6.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.9 CCD23574.1 - 0.00014 21.2 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 CCD23574.1 - 0.00019 20.6 0.1 0.0043 16.2 0.0 2.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CCD23574.1 - 0.0002 21.3 0.0 0.00033 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CCD23574.1 - 0.00026 20.0 0.0 0.00062 18.8 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 CCD23574.1 - 0.0011 19.3 0.0 0.0053 17.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.11 CCD23574.1 - 0.0052 16.3 0.0 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_11 PF08241.7 CCD23574.1 - 0.0066 16.9 0.0 0.021 15.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Ribosomal_S21e PF01249.13 CCD23575.1 - 2.9e-33 113.6 0.0 3.6e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e TcpE PF12648.2 CCD23575.1 - 0.12 12.5 1.3 0.19 11.9 0.9 1.2 1 0 0 1 1 1 0 TcpE family Glyco_transf_8 PF01501.15 CCD23576.1 - 1.3e-34 119.6 0.0 3.5e-34 118.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 8 DUF1460 PF07313.7 CCD23576.1 - 0.024 13.8 0.3 0.054 12.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) DEAD PF00270.24 CCD23577.1 - 1.8e-42 144.7 1.8 4e-42 143.5 0.2 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD23577.1 - 3.1e-28 97.4 0.2 1.7e-27 95.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD23577.1 - 8.5e-05 22.4 0.0 0.00028 20.7 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCD23577.1 - 0.0037 16.9 0.1 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain DUF1253 PF06862.7 CCD23577.1 - 0.0044 15.4 0.5 0.64 8.3 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_30 PF13604.1 CCD23577.1 - 0.034 13.7 0.1 0.25 10.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.1 CCD23577.1 - 0.042 13.7 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Ribosomal_L1 PF00687.16 CCD23578.1 - 1.9e-40 138.5 2.8 2.3e-40 138.2 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Phosducin PF02114.11 CCD23579.1 - 4e-07 29.0 0.1 4.9e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 CCD23579.1 - 0.00072 19.2 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin DIM1 PF02966.11 CCD23579.1 - 0.067 12.7 1.2 0.28 10.6 0.0 2.0 1 1 1 2 2 2 0 Mitosis protein DIM1 DUF4252 PF14060.1 CCD23579.1 - 0.14 11.6 3.3 0.2 11.2 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4252) Glyco_tran_WbsX PF14307.1 CCD23579.1 - 0.16 11.1 0.2 0.19 10.8 0.1 1.1 1 0 0 1 1 1 0 Glycosyltransferase WbsX PBP1_TM PF14812.1 CCD23581.1 - 1.8 8.9 11.7 7.3 6.9 8.1 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SIR2 PF02146.12 CCD23582.1 - 2e-32 112.3 0.0 2.7e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Sir2 family zf-CCCH PF00642.19 CCD23583.1 - 5.2e-05 22.8 2.8 9.7e-05 21.9 1.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 CCD23583.1 - 0.0078 16.4 40.0 0.0078 16.4 27.7 5.8 2 1 4 6 6 6 2 Nucleoporin FG repeat region Glycos_transf_3 PF00591.16 CCD23584.1 - 1.1e-78 264.1 0.0 1.5e-78 263.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 CCD23584.1 - 1.5e-12 46.9 0.1 7.2e-12 44.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain IncA PF04156.9 CCD23585.1 - 0.00051 19.6 18.5 0.00051 19.6 12.8 7.8 2 2 4 6 6 6 3 IncA protein DUF869 PF05911.6 CCD23585.1 - 0.0013 17.0 48.1 0.0013 17.0 33.4 3.3 1 1 2 3 3 3 2 Plant protein of unknown function (DUF869) TMCO5 PF14992.1 CCD23585.1 - 0.0058 15.7 25.5 0.0058 15.7 17.7 5.9 1 1 6 7 7 7 1 TMCO5 family Uds1 PF15456.1 CCD23585.1 - 0.0074 16.2 12.2 0.0074 16.2 8.5 9.8 4 1 6 10 10 10 1 Up-regulated During Septation Filament PF00038.16 CCD23585.1 - 3.4 7.0 135.4 1.3 8.3 31.8 5.8 1 1 4 5 5 5 0 Intermediate filament protein CLTH PF10607.4 CCD23586.1 - 0.012 15.2 1.0 0.015 14.9 0.7 1.1 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain DUF1978 PF09321.5 CCD23586.1 - 0.048 13.0 0.6 0.054 12.9 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1978) VHS PF00790.14 CCD23587.1 - 7e-48 161.8 0.1 3.9e-47 159.4 0.0 2.2 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 CCD23587.1 - 3.1e-21 75.8 1.5 4.5e-21 75.3 0.4 1.8 1 1 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 CCD23587.1 - 2.6e-13 49.7 1.4 2.6e-13 49.7 1.0 2.1 2 0 0 2 2 2 1 GAT domain HSA PF07529.8 CCD23588.1 - 1.8e-12 46.8 0.2 1.8e-12 46.8 0.1 2.7 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 CCD23588.1 - 2.2e-08 34.0 0.1 2.2e-08 34.0 0.1 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCD23588.1 - 0.016 15.2 0.0 0.076 13.0 0.0 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain BCIP PF13862.1 CCD23589.1 - 3.8e-50 170.0 3.6 5.8e-50 169.4 2.5 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein ThiF PF00899.16 CCD23590.1 - 8e-41 139.0 0.1 1.4e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CCD23590.1 - 3.4e-24 84.2 0.4 8.1e-24 83.0 0.3 1.7 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 CCD23590.1 - 1.3e-12 48.0 0.0 3.1e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 CCD23590.1 - 8.6e-06 25.8 0.3 8.8e-05 22.6 0.0 2.5 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CCD23590.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Herpes_BLRF2 PF05812.7 CCD23590.1 - 0.14 11.9 0.1 0.26 11.0 0.1 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein priB_priC PF07445.7 CCD23591.1 - 0.13 11.7 2.9 0.1 12.0 0.3 2.0 2 0 0 2 2 2 0 Primosomal replication protein priB and priC YL1 PF05764.8 CCD23591.1 - 0.36 10.3 12.8 0.65 9.5 8.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein WD40 PF00400.27 CCD23591.1 - 6.3 6.8 7.9 28 4.7 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Cys_Met_Meta_PP PF01053.15 CCD23592.1 - 4.5e-65 219.4 0.0 1.3e-64 217.9 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CCD23592.1 - 1e-06 27.7 0.0 2.7e-06 26.3 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CCD23592.1 - 0.00072 18.6 0.0 0.0011 18.0 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II TINF2_N PF14973.1 CCD23592.1 - 0.035 14.2 0.2 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus Rad60-SLD PF11976.3 CCD23593.1 - 9.1e-25 86.1 7.4 2.8e-24 84.5 1.3 3.5 2 1 1 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like DSS1_SEM1 PF05160.8 CCD23594.1 - 2.9e-20 71.7 12.8 4.7e-20 71.1 8.9 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family FtsH_ext PF06480.10 CCD23594.1 - 0.18 12.0 1.7 0.26 11.4 1.2 1.5 1 1 0 1 1 1 0 FtsH Extracellular AAA PF00004.24 CCD23595.1 - 1.7e-41 141.5 0.2 4e-41 140.3 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCD23595.1 - 3.3e-05 23.8 0.0 0.00021 21.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCD23595.1 - 5e-05 23.3 0.4 0.014 15.4 0.0 2.7 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CCD23595.1 - 7.6e-05 22.4 1.1 0.00026 20.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCD23595.1 - 0.00073 19.6 1.7 0.0091 16.1 0.2 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCD23595.1 - 0.00078 18.5 0.0 0.0017 17.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CCD23595.1 - 0.0051 16.6 0.0 0.019 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CCD23595.1 - 0.0052 16.0 0.2 0.04 13.1 0.1 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 CCD23595.1 - 0.0064 17.3 0.1 0.029 15.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCD23595.1 - 0.01 15.5 0.1 0.027 14.2 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 CCD23595.1 - 0.01 15.2 0.0 0.02 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF815 PF05673.8 CCD23595.1 - 0.012 14.5 0.1 0.036 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 CCD23595.1 - 0.013 14.6 0.1 0.035 13.2 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CCD23595.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCD23595.1 - 0.033 13.5 0.8 0.26 10.6 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 CCD23595.1 - 0.077 12.5 1.4 0.16 11.5 0.1 2.0 2 0 0 2 2 2 0 AAA domain BLOC1_2 PF10046.4 CCD23595.1 - 0.19 11.8 5.3 0.08 13.0 1.3 2.2 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 WD40 PF00400.27 CCD23596.1 - 3.3e-39 131.3 6.8 1.2e-10 40.8 0.2 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat NUC153 PF08159.7 CCD23597.1 - 7.9e-15 54.1 19.9 6.9e-14 51.1 4.0 3.3 3 0 0 3 3 3 2 NUC153 domain RIO1 PF01163.17 CCD23598.1 - 1.7e-70 236.2 3.9 1.7e-70 236.2 2.7 2.2 2 0 0 2 2 2 1 RIO1 family YL1 PF05764.8 CCD23598.1 - 0.0044 16.6 38.0 0.008 15.8 19.5 2.2 2 0 0 2 2 2 2 YL1 nuclear protein APH PF01636.18 CCD23598.1 - 0.017 14.8 0.7 0.47 10.1 0.2 2.3 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kei1 PF08552.6 CCD23599.1 - 3.5e-27 95.3 12.7 1.3e-25 90.2 8.8 2.0 1 1 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Aldo_ket_red PF00248.16 CCD23600.1 - 7.3e-48 162.8 0.0 8.9e-48 162.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BHD_3 PF10405.4 CCD23600.1 - 0.01 15.5 0.0 0.11 12.2 0.0 2.5 3 0 0 3 3 3 0 Rad4 beta-hairpin domain 3 SpoU_sub_bind PF08032.7 CCD23600.1 - 0.14 12.3 1.0 8.9 6.5 0.0 3.5 4 1 1 5 5 5 0 RNA 2'-O ribose methyltransferase substrate binding FHA PF00498.21 CCD23601.1 - 8.4e-06 25.8 0.1 2.3e-05 24.3 0.0 1.8 1 0 0 1 1 1 1 FHA domain RAI1 PF08652.6 CCD23602.1 - 6.3e-06 25.8 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease YCII PF03795.9 CCD23603.1 - 0.0015 18.6 0.0 0.0019 18.3 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Glyco_hydro_18 PF00704.23 CCD23604.1 - 3.2e-75 253.7 8.8 3.2e-75 253.7 6.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Orthopox_A36R PF05950.6 CCD23604.1 - 0.01 15.7 0.7 0.024 14.5 0.5 1.6 1 0 0 1 1 1 0 Orthopoxvirus A36R protein Sclerostin PF05463.6 CCD23604.1 - 0.061 12.8 0.4 0.11 11.9 0.3 1.4 1 0 0 1 1 1 0 Sclerostin (SOST) DUF4094 PF13334.1 CCD23604.1 - 0.073 13.4 0.3 0.21 12.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Ion_trans PF00520.26 CCD23604.1 - 0.16 11.2 1.2 0.31 10.2 0.8 1.4 1 0 0 1 1 1 0 Ion transport protein GPP34 PF05719.6 CCD23605.1 - 6.1e-61 206.0 0.0 8.8e-61 205.5 0.0 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) EF-hand_1 PF00036.27 CCD23607.1 - 1.6e-26 89.5 6.0 8.3e-08 31.0 0.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 CCD23607.1 - 1.8e-23 82.4 11.5 3.2e-14 52.7 0.5 3.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCD23607.1 - 2.2e-23 79.9 3.5 2.8e-06 26.7 0.3 4.7 5 0 0 5 5 4 3 EF-hand domain EF-hand_5 PF13202.1 CCD23607.1 - 1e-18 65.7 5.2 4e-05 22.7 0.5 4.2 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 CCD23607.1 - 4.8e-18 64.5 9.4 2.6e-07 30.1 0.4 3.5 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CCD23607.1 - 0.00024 20.7 5.8 1.8 8.3 0.1 3.4 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CCD23607.1 - 0.00091 19.0 0.8 0.013 15.3 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 CCD23607.1 - 0.0058 16.6 2.1 0.42 10.6 0.9 3.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region S10_plectin PF03501.10 CCD23607.1 - 0.014 15.2 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain Tenui_NCP PF04876.7 CCD23607.1 - 0.017 14.6 0.3 0.15 11.6 0.0 2.0 1 1 0 2 2 2 0 Tenuivirus major non-capsid protein EF-hand_10 PF14788.1 CCD23607.1 - 0.088 12.4 0.5 2.1 8.0 0.0 2.8 3 0 0 3 3 3 0 EF hand Acyltransferase PF01553.16 CCD23608.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.6 1 1 0 1 1 1 0 Acyltransferase Acyltransferase PF01553.16 CCD23609.1 - 1.2e-12 47.3 0.0 1.9e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Kinesin PF00225.18 CCD23610.1 - 3.3e-99 331.7 14.4 3.3e-99 331.7 10.0 3.0 3 2 1 4 4 4 1 Kinesin motor domain IncA PF04156.9 CCD23610.1 - 2.6 7.5 50.0 0.57 9.7 6.7 4.2 1 1 3 4 4 4 0 IncA protein V_ATPase_I PF01496.14 CCD23610.1 - 4.1 5.1 33.2 9.1 3.9 23.0 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Rrp15p PF07890.7 CCD23611.1 - 6.6e-32 110.2 13.0 6.6e-32 110.2 9.0 2.1 2 1 0 2 2 2 1 Rrp15p Metallophos PF00149.23 CCD23612.1 - 3.3e-39 134.3 0.0 5e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CCD23612.1 - 9.7e-22 76.4 2.5 6.3e-19 67.4 0.5 3.0 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CCD23612.1 - 4.5e-17 60.8 5.7 4.6e-07 29.1 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCD23612.1 - 4.9e-14 51.0 0.6 4.6e-05 23.0 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat PPP5 PF08321.7 CCD23612.1 - 2.3e-12 46.7 0.2 1.8e-05 24.6 0.0 3.2 3 0 0 3 3 3 2 PPP5 TPR repeat region TPR_9 PF13371.1 CCD23612.1 - 8.2e-06 25.5 0.0 0.0013 18.5 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCD23612.1 - 1.5e-05 24.8 0.4 0.27 11.5 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCD23612.1 - 0.00019 21.7 0.5 0.00086 19.5 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCD23612.1 - 0.0006 19.6 2.1 0.35 10.8 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCD23612.1 - 0.0014 19.2 0.1 0.69 10.6 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat DUF1563 PF07599.6 CCD23612.1 - 0.0028 17.4 0.6 0.0098 15.7 0.4 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1563) TPR_8 PF13181.1 CCD23612.1 - 0.0036 16.9 4.3 0.072 12.9 0.6 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat Metallophos_2 PF12850.2 CCD23612.1 - 0.013 15.3 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TPR_14 PF13428.1 CCD23612.1 - 0.024 15.2 0.0 2.6 8.9 0.0 3.3 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCD23612.1 - 0.04 13.7 0.4 0.23 11.3 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCD23612.1 - 0.061 13.2 3.6 0.47 10.3 0.0 3.1 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 CCD23612.1 - 0.099 12.5 3.0 0.31 10.9 2.1 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain CBF PF03914.12 CCD23613.1 - 2.2e-42 144.2 1.5 2.2e-42 144.2 1.1 2.1 2 1 0 2 2 2 1 CBF/Mak21 family Asn_synthase PF00733.16 CCD23614.1 - 4.1e-70 236.1 0.0 6.2e-70 235.6 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CCD23614.1 - 8.2e-34 116.0 0.0 1.4e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CCD23614.1 - 2.7e-28 98.5 0.0 7.4e-28 97.1 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CCD23614.1 - 1.1e-07 31.2 0.0 2e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 CCD23614.1 - 0.00018 20.3 0.0 0.74 8.4 0.0 3.0 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 CCD23614.1 - 0.0014 17.6 0.0 0.0024 16.8 0.0 1.3 1 0 0 1 1 1 1 NAD synthase DUF2305 PF10230.4 CCD23616.1 - 3.7e-59 200.3 2.3 4.3e-59 200.1 1.6 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 CCD23616.1 - 0.0036 17.2 0.0 0.0057 16.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCD23616.1 - 0.0067 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 CCD23616.1 - 0.034 13.2 0.0 0.087 11.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) BAR_2 PF10455.4 CCD23618.1 - 2.2e-88 295.9 61.0 5.9e-66 222.3 30.6 2.5 1 1 1 2 2 2 2 Bin/amphiphysin/Rvs domain for vesicular trafficking MARVEL PF01284.18 CCD23620.1 - 1.1e-25 90.1 16.3 1.4e-25 89.7 11.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4345 PF14248.1 CCD23620.1 - 0.024 14.1 0.6 0.024 14.1 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4345) Pet20 PF08692.5 CCD23621.1 - 7.8e-46 155.4 2.5 1.3e-45 154.6 1.8 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet20 Pheromone PF08015.6 CCD23621.1 - 6.1 7.7 11.2 12 6.8 5.0 2.3 2 0 0 2 2 2 0 Fungal mating-type pheromone WW PF00397.21 CCD23622.1 - 1.5e-12 47.1 8.0 2.8e-09 36.6 3.8 3.1 3 0 0 3 3 3 2 WW domain FF PF01846.14 CCD23622.1 - 2.3e-09 37.0 1.7 2.3e-09 37.0 1.2 2.2 2 0 0 2 2 2 1 FF domain SH3_1 PF00018.23 CCD23624.1 - 2.1e-15 55.8 0.0 3.5e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCD23624.1 - 2.8e-14 52.4 0.0 4.4e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCD23624.1 - 7.7e-11 41.3 0.0 1.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF2076 PF09849.4 CCD23624.1 - 0.2 11.7 14.1 0.27 11.2 9.5 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Suf PF05843.9 CCD23624.1 - 0.25 11.0 4.4 0.25 11.0 3.0 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.4 CCD23624.1 - 0.35 9.0 25.5 0.43 8.7 17.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PRCC PF10253.4 CCD23624.1 - 1.5 9.5 12.9 0.2 12.3 6.2 1.6 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting NCA2 PF08637.5 CCD23625.1 - 1.1e-94 316.6 8.3 1.1e-94 316.6 5.8 1.8 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 Filo_VP35 PF02097.10 CCD23625.1 - 0.087 12.0 2.8 0.081 12.1 0.7 1.8 2 0 0 2 2 2 0 Filoviridae VP35 Cgr1 PF03879.9 CCD23626.1 - 0.093 12.9 5.8 1.3 9.2 1.3 2.4 2 0 0 2 2 2 0 Cgr1 family Zip PF02535.17 CCD23626.1 - 0.13 11.2 2.9 0.14 11.1 2.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Innate_immun PF12782.2 CCD23626.1 - 6.3 5.9 10.5 9.8 5.2 7.3 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family SKN1 PF03935.10 CCD23627.1 - 4.3e-256 849.8 7.2 5.9e-256 849.4 5.0 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Phosphorylase PF00343.15 CCD23628.1 - 0 1043.8 2.3 0 1043.6 1.6 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase CDP-OH_P_transf PF01066.16 CCD23629.1 - 2.8e-11 43.6 3.0 2.8e-11 43.6 2.1 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase SOG2 PF10428.4 CCD23630.1 - 0.62 8.6 13.7 0.72 8.4 9.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Macoilin PF09726.4 CCD23630.1 - 2.2 6.4 11.8 2.6 6.2 8.2 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF912 PF06024.7 CCD23630.1 - 2.5 8.1 7.8 4.4 7.4 4.9 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SR-25 PF10500.4 CCD23630.1 - 3.8 6.9 11.5 5.5 6.4 8.0 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Menin PF05053.8 CCD23630.1 - 5.5 5.0 8.7 7 4.6 6.0 1.1 1 0 0 1 1 1 0 Menin Clathrin PF00637.15 CCD23631.1 - 8.8e-190 621.9 55.4 2.5e-34 117.9 1.5 8.3 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CCD23631.1 - 1.4e-24 85.7 0.3 7.3e-24 83.4 0.1 2.4 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 CCD23631.1 - 8.4e-15 53.9 8.3 0.00092 19.3 0.1 6.6 7 0 0 7 7 7 5 Clathrin propeller repeat Clathrin-link PF09268.5 CCD23631.1 - 2.6e-09 35.8 0.4 2.6e-09 35.8 0.2 3.0 4 0 0 4 4 4 1 Clathrin, heavy-chain linker SPT16 PF08644.6 CCD23632.1 - 7.4e-50 168.7 0.1 7.4e-50 168.7 0.1 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 CCD23632.1 - 7.6e-46 155.6 1.2 1.6e-45 154.5 0.2 2.2 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 CCD23632.1 - 5e-24 85.0 0.0 1.1e-23 83.9 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 CCD23632.1 - 5.4e-19 67.9 0.8 4.5e-18 65.0 0.0 2.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like AMPKBI PF04739.10 CCD23633.1 - 1.6e-31 108.1 4.5 1.6e-31 108.1 3.1 3.7 4 0 0 4 4 4 1 5'-AMP-activated protein kinase beta subunit, interation domain Suf PF05843.9 CCD23633.1 - 1.7 8.3 23.2 0.95 9.1 6.6 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) zf-H2C2_2 PF13465.1 CCD23634.1 - 7.4e-06 25.9 25.6 8.1e-05 22.7 5.2 4.1 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCD23634.1 - 1.1e-05 25.4 16.5 0.00047 20.2 1.9 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCD23634.1 - 7.5e-05 22.8 24.1 0.00014 22.0 3.0 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCD23634.1 - 0.24 11.5 0.1 0.24 11.5 0.1 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding LSM PF01423.17 CCD23635.1 - 1.5e-19 69.2 0.6 1.5e-19 69.2 0.4 1.5 2 0 0 2 2 2 1 LSM domain CHZ PF09649.5 CCD23636.1 - 9.4e-21 72.7 1.8 9.4e-21 72.7 1.2 2.5 4 0 0 4 4 4 1 Histone chaperone domain CHZ DUF2011 PF09428.5 CCD23636.1 - 0.0089 15.9 9.5 0.47 10.3 5.5 2.1 2 0 0 2 2 2 2 Fungal protein of unknown function (DUF2011) BUD22 PF09073.5 CCD23636.1 - 4.4 6.2 27.4 5.4 5.9 19.0 1.1 1 0 0 1 1 1 0 BUD22 DUF3752 PF12572.3 CCD23636.1 - 6 6.9 17.7 0.79 9.8 7.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3752) TT_ORF2 PF02957.10 CCD23636.1 - 6.2 7.5 12.8 1.2 9.8 4.6 2.2 2 0 0 2 2 2 0 TT viral ORF2 DUF2547 PF10818.3 CCD23639.1 - 4.7 7.9 12.2 2.2 8.9 4.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) TT_ORF2 PF02957.10 CCD23639.1 - 5 7.8 8.2 0.9 10.2 1.9 2.2 2 0 0 2 2 2 0 TT viral ORF2 Eapp_C PF10238.4 CCD23640.1 - 0.12 12.2 7.8 0.17 11.8 5.4 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein PNRC PF15365.1 CCD23640.1 - 0.18 11.8 0.5 0.18 11.8 0.3 2.7 2 2 1 3 3 3 0 Proline-rich nuclear receptor coactivator Sigma_reg_N PF13800.1 CCD23640.1 - 1.4 9.0 4.3 1.7 8.7 0.2 2.5 1 1 0 2 2 2 0 Sigma factor regulator N-terminal Zip PF02535.17 CCD23640.1 - 4.4 6.2 11.7 5.2 5.9 8.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Nse5 PF08691.5 CCD23641.1 - 1.8e-21 76.2 28.3 8.9e-14 50.8 2.4 2.4 2 1 0 2 2 2 2 DNA repair proteins Nse5 and Nse6 CDC45 PF02724.9 CCD23641.1 - 2 6.3 9.5 3.1 5.7 6.6 1.3 1 0 0 1 1 1 0 CDC45-like protein UAA PF08449.6 CCD23642.1 - 5.8e-14 51.7 22.3 9.1e-14 51.0 15.4 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CCD23642.1 - 1.9e-11 43.8 5.4 1.9e-11 43.8 3.8 2.6 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CCD23642.1 - 9.4e-09 35.3 28.1 0.00016 21.7 3.6 2.4 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.14 CCD23642.1 - 1.9 9.0 11.4 6.4 7.3 3.2 3.1 2 1 1 3 3 3 0 Small Multidrug Resistance protein GATA PF00320.22 CCD23643.1 - 2.2e-17 62.0 4.4 8.2e-17 60.2 3.1 2.1 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CCD23643.1 - 0.11 11.8 0.9 0.26 10.6 0.6 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Glyco_transf_21 PF13506.1 CCD23644.1 - 0.045 13.0 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 21 XPG_I PF00867.13 CCD23645.1 - 4e-22 78.0 0.0 1.4e-21 76.3 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 CCD23645.1 - 9.5e-06 25.8 0.0 3.1e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 XPG N-terminal domain PMSR PF01625.16 CCD23646.1 - 2.1e-50 170.6 0.4 2.8e-50 170.2 0.2 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF3889 PF13028.1 CCD23646.1 - 0.091 12.4 1.2 1.7 8.3 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3889) AdoHcyase PF05221.12 CCD23647.1 - 5.2e-139 461.7 0.1 6e-139 461.5 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CCD23647.1 - 3.5e-86 287.0 2.9 5.5e-86 286.4 2.0 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CCD23647.1 - 3.6e-08 32.7 0.1 6.9e-08 31.8 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CCD23647.1 - 0.00031 20.1 0.3 0.00058 19.2 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CCD23647.1 - 0.0012 18.8 0.1 0.0026 17.7 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Oxidored_nitro PF00148.14 CCD23647.1 - 0.034 12.7 0.2 0.32 9.5 0.0 2.4 3 0 0 3 3 3 0 Nitrogenase component 1 type Oxidoreductase ELFV_dehydrog PF00208.16 CCD23647.1 - 0.039 13.5 0.1 0.068 12.7 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase RPM2 PF08579.6 CCD23647.1 - 0.092 12.8 0.0 0.24 11.5 0.0 1.6 2 0 0 2 2 2 0 Mitochondrial ribonuclease P subunit (RPM2) RVT_2 PF07727.9 CCD23648.1 - 2.4e-38 131.4 0.1 4.8e-38 130.5 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCD23648.1 - 9.1e-20 70.9 0.0 2.6e-19 69.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCD23648.1 - 9.5e-06 25.1 0.4 3.9e-05 23.2 0.3 2.1 1 0 0 1 1 1 1 GAG-pre-integrase domain zf-CCHC PF00098.18 CCD23648.1 - 0.083 12.8 3.4 0.16 11.9 2.4 1.5 1 0 0 1 1 1 0 Zinc knuckle SAPS PF04499.10 CCD23650.1 - 1e-153 512.4 16.9 1e-153 512.4 11.7 2.5 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein DnaJ PF00226.26 CCD23651.1 - 1.4e-12 47.1 5.9 2.7e-12 46.2 4.1 1.5 1 0 0 1 1 1 1 DnaJ domain KH_3 PF13014.1 CCD23651.1 - 0.071 12.7 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 KH domain YMF19 PF02326.10 CCD23651.1 - 2.7 8.6 7.2 30 5.2 0.3 3.4 3 0 0 3 3 3 0 Plant ATP synthase F0 Adaptin_binding PF10199.4 CCD23653.1 - 2.5e-07 31.0 1.9 0.004 17.4 0.1 2.3 1 1 1 2 2 2 2 Alpha and gamma adaptin binding protein p34 Inos-1-P_synth PF01658.12 CCD23653.1 - 0.066 13.0 0.5 0.15 11.8 0.4 1.6 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Peptidase_M20 PF01546.23 CCD23654.1 - 1.3e-30 106.2 0.0 1.9e-30 105.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCD23654.1 - 2e-12 46.8 0.0 3.2e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF848 PF05852.6 CCD23654.1 - 0.084 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) HSBP1 PF06825.7 CCD23654.1 - 0.25 10.9 1.0 6.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Mito_carr PF00153.22 CCD23655.1 - 7.3e-48 160.2 5.7 1.4e-22 79.1 0.1 4.5 3 2 0 3 3 3 3 Mitochondrial carrier protein CUB PF00431.15 CCD23655.1 - 0.032 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 CUB domain ATP-synt_E_2 PF08112.6 CCD23656.1 - 0.47 10.5 11.0 0.12 12.4 1.1 3.4 3 0 0 3 3 3 0 ATP synthase epsilon subunit IBN_N PF03810.14 CCD23657.1 - 8.4e-11 41.6 5.8 1.2e-10 41.1 0.0 4.0 5 0 0 5 5 5 1 Importin-beta N-terminal domain DUF1546 PF07571.8 CCD23657.1 - 0.18 11.9 1.4 9.3 6.4 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1546) Ank PF00023.25 CCD23658.1 - 2.9e-13 48.9 0.1 1.2e-05 24.8 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 CCD23658.1 - 1e-10 41.7 0.0 6.2e-10 39.2 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCD23658.1 - 1.7e-10 40.7 0.1 4.5e-05 23.5 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD23658.1 - 5.1e-09 35.5 0.0 0.0017 18.4 0.0 3.6 4 1 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 CCD23658.1 - 1.9e-06 28.1 0.3 0.0082 16.6 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF155 PF02582.9 CCD23659.1 - 4.4e-58 196.0 0.2 7.4e-58 195.3 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Brr6_like_C_C PF10104.4 CCD23660.1 - 1.7e-40 137.6 4.4 2e-40 137.4 3.1 1.0 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF2638 PF10937.3 CCD23661.1 - 6e-29 101.3 0.0 6.9e-29 101.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Proteasome PF00227.21 CCD23662.1 - 2.6e-24 85.5 0.0 3.3e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Clat_adaptor_s PF01217.15 CCD23663.1 - 1.4e-07 31.3 4.6 2e-07 30.8 1.3 2.3 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.16 CCD23663.1 - 2.6e-05 23.4 0.4 4.1e-05 22.8 0.3 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family DUF1764 PF08576.5 CCD23663.1 - 7.2 7.4 9.5 1.5 9.5 1.2 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) Ppx-GppA PF02541.11 CCD23664.1 - 7e-57 192.7 0.0 9.5e-57 192.3 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family SAC3_GANP PF03399.11 CCD23665.1 - 6.9e-27 94.3 2.4 8.9e-27 93.9 1.7 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCD23665.1 - 3.4e-19 69.0 0.1 5.2e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Thymopoietin PF08198.6 CCD23665.1 - 0.0016 17.9 1.3 0.0035 16.8 0.1 2.0 2 0 0 2 2 2 1 Thymopoietin protein Hexokinase_2 PF03727.11 CCD23666.1 - 1.5e-95 319.0 0.0 1.9e-95 318.7 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCD23666.1 - 6.7e-81 270.5 0.0 5.7e-80 267.4 0.0 2.1 2 0 0 2 2 2 1 Hexokinase DUF2294 PF10057.4 CCD23666.1 - 0.11 12.1 0.0 0.61 9.7 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) GST_N PF02798.15 CCD23667.1 - 1.7e-10 40.9 0.0 3.3e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCD23667.1 - 5e-09 36.0 0.0 8.8e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCD23667.1 - 7.1e-06 26.1 0.0 1.5e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCD23667.1 - 0.0037 17.2 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCD23667.1 - 0.0074 16.7 0.0 0.013 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCD23667.1 - 0.025 14.4 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCD23668.1 - 1.6e-12 47.2 0.0 9e-12 44.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCD23668.1 - 0.0001 22.0 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCD23668.1 - 0.0083 16.3 0.0 0.033 14.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain NSP13 PF06460.7 CCD23668.1 - 0.063 12.1 0.0 0.092 11.6 0.0 1.2 1 0 0 1 1 1 0 Coronavirus NSP13 CENP-B_dimeris PF09026.5 CCD23669.1 - 0.12 12.5 4.8 0.26 11.5 3.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CENP-B_dimeris PF09026.5 CCD23670.1 - 0.12 12.6 4.8 0.26 11.5 3.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain adh_short PF00106.20 CCD23673.1 - 3.6e-28 98.5 0.0 4.9e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCD23673.1 - 8.4e-14 51.9 0.2 1e-13 51.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCD23673.1 - 3.5e-10 39.8 0.0 4.6e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCD23673.1 - 2.3e-05 23.9 0.2 3.9e-05 23.2 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 CCD23673.1 - 0.018 15.0 0.2 0.038 13.9 0.2 1.5 1 0 0 1 1 1 0 TrkA-N domain tRNA_m1G_MT PF01746.16 CCD23673.1 - 0.055 13.0 0.2 0.095 12.2 0.1 1.4 1 0 0 1 1 1 0 tRNA (Guanine-1)-methyltransferase Polysacc_synt_2 PF02719.10 CCD23673.1 - 0.064 12.1 0.0 0.095 11.5 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ADK PF00406.17 CCD23674.1 - 3.2e-48 163.4 0.0 4e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CCD23674.1 - 3.9e-11 43.3 0.0 6.2e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCD23674.1 - 8.6e-09 36.2 0.0 1.5e-08 35.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCD23674.1 - 5.1e-07 29.6 0.0 1e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CCD23674.1 - 2.5e-06 26.9 0.4 0.032 13.6 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Zeta_toxin PF06414.7 CCD23674.1 - 0.00062 18.9 0.0 0.00078 18.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Myotub-related PF06602.9 CCD23674.1 - 0.029 13.1 0.0 0.063 12.0 0.0 1.5 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain SRP54 PF00448.17 CCD23674.1 - 0.044 13.2 0.0 0.056 12.8 0.0 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain UPF0302 PF08864.5 CCD23675.1 - 0.002 17.9 0.3 0.0028 17.4 0.2 1.3 1 0 0 1 1 1 1 UPF0302 domain Consortin_C PF15281.1 CCD23675.1 - 0.02 14.3 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Consortin C-terminus DUF912 PF06024.7 CCD23675.1 - 0.03 14.3 0.2 0.036 14.1 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TPR_1 PF00515.23 CCD23677.1 - 1.1e-35 119.7 5.1 9e-06 25.0 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 CCD23677.1 - 1.5e-32 108.8 3.4 0.00064 19.4 0.0 9.9 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 CCD23677.1 - 6.2e-30 102.6 8.3 8.2e-09 34.9 0.1 6.7 6 0 0 6 6 6 5 TPR repeat Apc3 PF12895.2 CCD23677.1 - 8.7e-24 83.4 13.9 2.8e-19 69.0 0.0 5.4 4 1 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCD23677.1 - 3.6e-22 76.4 9.5 0.0023 17.5 0.3 8.3 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCD23677.1 - 1e-21 77.0 0.0 7.8e-07 29.3 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCD23677.1 - 1.6e-18 66.3 9.5 1.5e-06 28.0 0.2 8.3 6 3 1 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCD23677.1 - 1.9e-16 59.0 0.0 0.0033 17.9 0.0 8.4 7 2 2 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCD23677.1 - 2.3e-16 59.9 0.0 3.7e-06 27.4 0.0 5.5 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCD23677.1 - 3.3e-14 51.4 4.1 0.00015 21.3 0.0 7.4 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCD23677.1 - 1.6e-13 49.6 3.8 0.02 15.0 0.0 8.9 8 1 1 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCD23677.1 - 1.9e-10 40.5 2.3 0.72 10.4 0.0 8.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.1 CCD23677.1 - 6.6e-08 32.2 0.0 0.53 10.3 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCD23677.1 - 6.7e-07 28.6 0.9 0.41 9.6 0.0 4.0 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 CCD23677.1 - 0.00073 19.3 0.0 0.021 14.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCD23677.1 - 0.066 13.1 9.5 1 9.2 0.2 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 CCD23677.1 - 0.074 13.1 0.0 4.5 7.4 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat SPO22 PF08631.5 CCD23677.1 - 2.6 7.0 11.0 0.72 8.8 1.9 3.3 4 0 0 4 4 4 0 Meiosis protein SPO22/ZIP4 like WD40 PF00400.27 CCD23678.1 - 7.3e-32 108.0 3.1 8.2e-08 31.8 0.3 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 CCD23678.1 - 8.7e-05 20.8 0.5 0.013 13.6 0.1 2.4 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCD23678.1 - 0.022 13.5 3.4 2.9 6.5 0.1 3.6 2 1 2 4 4 4 0 Nup133 N terminal like RAB3GAP2_N PF14655.1 CCD23678.1 - 0.042 12.8 2.4 0.36 9.7 0.0 3.0 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ank PF00023.25 CCD23679.1 - 4.6e-15 54.5 0.1 5.4e-07 29.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CCD23679.1 - 9.9e-12 45.0 2.3 1e-11 44.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCD23679.1 - 4.9e-11 42.8 0.1 1.5e-10 41.2 0.1 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD23679.1 - 6.7e-09 35.1 0.5 4.2e-05 23.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 CCD23679.1 - 4.2e-08 33.0 6.4 4.2e-08 33.0 4.4 4.0 3 1 0 3 3 3 1 IPT/TIG domain Ank_5 PF13857.1 CCD23679.1 - 0.00015 21.8 0.0 0.00015 21.8 0.0 3.7 3 1 1 4 4 4 2 Ankyrin repeats (many copies) ORC5_C PF14630.1 CCD23680.1 - 1.4e-61 208.3 3.4 1.4e-61 208.3 2.3 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 CCD23680.1 - 4.7e-08 33.2 0.0 8.4e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCD23680.1 - 0.0028 17.8 0.0 0.0079 16.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCD23680.1 - 0.14 12.0 3.5 0.45 10.4 0.4 3.0 2 1 0 2 2 2 0 AAA domain DnaJ PF00226.26 CCD23681.1 - 2.7e-16 59.0 0.9 8.8e-16 57.4 0.6 1.9 1 0 0 1 1 1 1 DnaJ domain L27_2 PF09045.5 CCD23681.1 - 0.25 10.9 1.8 28 4.3 0.1 3.7 4 0 0 4 4 4 0 L27_2 PPTA PF01239.17 CCD23682.1 - 8.2e-36 119.8 25.4 1.6e-07 30.3 0.3 5.9 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat DUF1748 PF08520.5 CCD23683.1 - 3.7e-17 61.7 0.1 4.7e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) WD40 PF00400.27 CCD23684.1 - 4.3e-13 48.5 0.1 7.1e-05 22.5 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Lactonase PF10282.4 CCD23684.1 - 2.8e-05 23.3 0.0 0.00036 19.7 0.0 2.3 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Coatomer_WDAD PF04053.9 CCD23684.1 - 0.086 11.6 1.1 0.53 9.0 0.1 2.4 2 1 0 3 3 3 0 Coatomer WD associated region AAA_12 PF13087.1 CCD23685.1 - 1.5e-58 197.4 0.5 4.8e-58 195.8 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CCD23685.1 - 4e-52 177.1 0.0 4e-52 177.1 0.0 1.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CCD23685.1 - 4e-13 48.9 0.0 9.5e-13 47.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCD23685.1 - 5.6e-11 42.3 0.0 1.5e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CCD23685.1 - 1.2e-07 31.4 0.2 0.29 10.6 0.0 3.5 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CCD23685.1 - 7.9e-06 25.3 0.5 3.2e-05 23.3 0.0 2.2 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 CCD23685.1 - 6.9e-05 22.1 0.0 0.001 18.3 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.24 CCD23685.1 - 0.00013 21.5 0.1 0.0082 15.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CCD23685.1 - 0.00017 21.4 1.8 0.00032 20.5 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 CCD23685.1 - 0.0002 21.0 0.0 0.0029 17.2 0.0 2.7 3 0 0 3 3 3 1 Helicase AAA_22 PF13401.1 CCD23685.1 - 0.00023 21.3 0.0 0.0048 17.0 0.0 2.5 1 1 0 2 2 2 1 AAA domain PIF1 PF05970.9 CCD23685.1 - 0.0017 17.3 0.1 0.29 10.0 0.0 2.5 2 0 0 2 2 2 1 PIF1-like helicase TrwB_AAD_bind PF10412.4 CCD23685.1 - 0.0021 16.7 0.0 0.0045 15.6 0.0 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain Zot PF05707.7 CCD23685.1 - 0.0032 16.9 0.0 0.0079 15.6 0.0 1.7 1 0 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_10 PF12846.2 CCD23685.1 - 0.0066 15.9 0.0 0.014 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA-like domain AAA PF00004.24 CCD23685.1 - 0.0089 16.2 0.1 0.049 13.8 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CCD23685.1 - 0.009 15.0 0.2 0.038 12.9 0.0 2.0 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 CCD23685.1 - 0.011 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 CCD23685.1 - 0.02 14.8 0.0 0.075 13.0 0.0 1.9 2 0 0 2 2 1 0 AAA ATPase domain T2SE PF00437.15 CCD23685.1 - 0.024 13.5 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 CCD23685.1 - 0.025 14.4 1.4 0.14 12.0 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF853 PF05872.7 CCD23685.1 - 0.025 12.9 0.0 0.039 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Flavi_DEAD PF07652.9 CCD23685.1 - 0.069 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain MobB PF03205.9 CCD23685.1 - 0.071 12.8 2.2 0.45 10.2 0.0 3.1 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 CCD23685.1 - 0.098 13.4 2.0 0.25 12.1 0.3 2.6 3 1 0 3 3 1 0 AAA domain UvrD_C_2 PF13538.1 CCD23685.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Mt_ATP-synt_D PF05873.7 CCD23686.1 - 4.2e-14 52.4 2.4 5.5e-14 52.1 1.7 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF4201 PF13870.1 CCD23686.1 - 0.019 14.3 4.3 0.1 12.0 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Vac_Fusion PF02346.11 CCD23686.1 - 0.064 12.6 0.1 0.21 11.0 0.0 1.9 2 0 0 2 2 2 0 Chordopoxvirus fusion protein IncA PF04156.9 CCD23686.1 - 0.089 12.3 2.9 0.12 11.9 2.0 1.2 1 0 0 1 1 1 0 IncA protein U-box PF04564.10 CCD23686.1 - 0.11 12.5 0.4 1.8 8.6 0.0 2.2 2 0 0 2 2 2 0 U-box domain V_ATPase_I PF01496.14 CCD23686.1 - 0.15 9.9 3.9 0.17 9.6 2.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF148 PF02520.12 CCD23686.1 - 0.6 9.9 5.3 0.55 10.0 2.0 2.1 1 1 0 2 2 2 0 Domain of unknown function DUF148 FlxA PF14282.1 CCD23686.1 - 4 7.4 8.8 15 5.6 2.0 2.2 1 1 1 2 2 2 0 FlxA-like protein Fungal_trans PF04082.13 CCD23687.1 - 8.3e-23 80.5 0.7 8.3e-23 80.5 0.5 2.8 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD23687.1 - 1.2e-09 37.9 11.4 2.2e-09 37.0 7.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ARPC4 PF05856.7 CCD23688.1 - 1.5e-72 242.4 3.7 1.7e-72 242.3 2.6 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Peptidase_S24 PF00717.18 CCD23689.1 - 4.8e-08 32.5 0.0 7.9e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 Peptidase S24-like Ydc2-catalyt PF09159.5 CCD23690.1 - 1.7e-44 152.3 10.1 5.1e-44 150.8 7.0 1.7 1 1 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 CCD23690.1 - 0.058 13.2 2.3 7.7 6.3 0.0 3.2 4 0 0 4 4 4 0 Poxvirus A22 protein DUF1673 PF07895.6 CCD23690.1 - 0.79 9.2 8.3 1.7 8.1 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Secretin_N_2 PF07655.8 CCD23690.1 - 2 8.8 12.5 6 7.3 8.7 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain MIP PF00230.15 CCD23691.1 - 4.7e-43 147.2 13.3 6e-43 146.9 9.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein Flavoprotein PF02441.14 CCD23692.1 - 1.8e-40 137.5 0.1 6e-40 135.8 0.1 1.9 1 0 0 1 1 1 1 Flavoprotein Cyto_heme_lyase PF01265.12 CCD23693.1 - 5.3e-69 232.6 9.7 6.2e-69 232.4 6.7 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase ParBc PF02195.13 CCD23694.1 - 9.8e-13 48.0 0.0 1.2e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Ldh_1_C PF02866.13 CCD23695.1 - 7.4e-50 169.0 0.1 1e-49 168.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CCD23695.1 - 6.6e-43 145.9 0.0 9.5e-43 145.4 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CCD23695.1 - 0.00037 19.2 0.0 0.00059 18.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CCD23695.1 - 0.026 14.8 0.1 0.14 12.4 0.0 2.3 4 0 0 4 4 4 0 Semialdehyde dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 CCD23695.1 - 0.086 11.9 0.3 0.45 9.5 0.0 2.3 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 CCD23695.1 - 0.095 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding zf-CHY PF05495.7 CCD23696.1 - 8.8e-13 48.2 15.6 1.4e-12 47.6 10.8 1.3 1 0 0 1 1 1 1 CHY zinc finger Rpr2 PF04032.11 CCD23696.1 - 0.53 10.2 11.4 0.45 10.4 0.9 2.7 1 1 1 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Ank_2 PF12796.2 CCD23697.1 - 5.1e-22 78.0 0.9 1.6e-11 44.4 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCD23697.1 - 5.2e-18 65.0 6.8 6.9e-08 32.7 0.2 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CCD23697.1 - 2.1e-17 61.9 11.0 3.5e-05 23.3 0.2 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 CCD23697.1 - 7.3e-11 41.2 9.2 0.0016 18.5 0.0 4.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 CCD23697.1 - 4.5e-10 39.4 4.7 0.00056 20.0 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) EF1G PF00647.14 CCD23698.1 - 6.1e-48 160.9 0.1 1.2e-47 159.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CCD23698.1 - 3.8e-12 46.0 0.1 3.8e-12 46.0 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCD23698.1 - 7.5e-10 38.8 0.0 2.1e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCD23698.1 - 4e-06 26.6 0.2 8.1e-06 25.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCD23698.1 - 0.00085 19.7 1.0 0.0014 19.1 0.1 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCD23698.1 - 0.0037 17.4 0.0 0.0083 16.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain BOP1NT PF08145.7 CCD23700.1 - 7.1e-102 340.5 6.5 7.1e-102 340.5 4.5 1.9 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 CCD23700.1 - 4.4e-27 92.9 6.2 5.8e-11 41.8 0.2 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat Colicin_D PF11429.3 CCD23700.1 - 0.058 13.5 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 Colicin D GAF_2 PF13185.1 CCD23701.1 - 0.00013 22.4 0.0 0.00016 22.1 0.0 1.3 1 1 0 1 1 1 1 GAF domain V_ATPase_I PF01496.14 CCD23702.1 - 0.025 12.4 3.8 0.039 11.8 2.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HSP70 PF00012.15 CCD23703.1 - 2.3e-53 181.0 6.0 2.3e-53 181.0 4.2 2.2 2 0 0 2 2 2 1 Hsp70 protein DUF1111 PF06537.6 CCD23703.1 - 0.041 12.1 0.0 0.041 12.1 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1111) RRM_5 PF13893.1 CCD23704.1 - 5e-06 26.2 0.1 0.0037 17.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCD23704.1 - 5.6e-05 22.6 0.0 0.016 14.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD23704.1 - 0.0017 18.2 0.0 0.27 11.2 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Plant_vir_prot PF01307.12 CCD23704.1 - 0.14 11.8 0.3 0.38 10.4 0.2 1.7 1 0 0 1 1 1 0 Plant viral movement protein MSA-2c PF12238.3 CCD23705.1 - 0.0037 16.9 3.8 0.39 10.3 0.3 2.5 2 0 0 2 2 2 2 Merozoite surface antigen 2c DUF4448 PF14610.1 CCD23706.1 - 5.8e-57 192.2 0.7 1e-56 191.4 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3290 PF11694.3 CCD23706.1 - 0.063 13.0 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Nucleoside_tran PF01733.13 CCD23706.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Nucleoside transporter Sen15 PF09631.5 CCD23707.1 - 1.7e-30 105.1 0.1 2e-30 104.9 0.1 1.0 1 0 0 1 1 1 1 Sen15 protein HA2 PF04408.18 CCD23708.1 - 1.1e-18 67.0 0.0 2.6e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCD23708.1 - 1.7e-18 66.5 0.0 4.1e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCD23708.1 - 3.2e-10 39.7 0.0 1.5e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD23708.1 - 2.8e-09 36.7 0.0 5.5e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCD23708.1 - 4.9e-07 29.9 0.0 3e-06 27.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCD23708.1 - 0.00082 19.0 0.0 0.0034 17.1 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 CCD23708.1 - 0.0036 16.7 0.3 0.0094 15.4 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.17 CCD23708.1 - 0.014 14.8 0.0 0.07 12.5 0.0 2.0 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 CCD23708.1 - 0.021 14.7 0.1 0.18 11.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCD23708.1 - 0.041 13.0 0.0 0.081 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 CCD23708.1 - 0.063 12.7 0.0 3.3 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 CCD23708.1 - 0.074 13.0 0.0 0.18 11.7 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CCD23708.1 - 0.14 12.4 2.3 0.26 11.6 0.0 2.5 2 1 1 3 3 3 0 ABC transporter FtsK_SpoIIIE PF01580.13 CCD23708.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 CCD23708.1 - 0.36 11.1 5.5 0.074 13.3 0.3 2.3 1 1 1 2 2 2 0 AAA domain Kinesin PF00225.18 CCD23709.1 - 2.6e-44 151.3 7.4 2.6e-44 151.3 5.1 2.2 2 1 0 2 2 2 1 Kinesin motor domain DUF2870 PF11069.3 CCD23709.1 - 1.2 9.1 0.0 1.2 9.1 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2870) V-ATPase_C PF03223.10 CCD23710.1 - 9.3e-123 409.7 5.2 1e-122 409.6 3.6 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NUC130_3NT PF08158.7 CCD23710.1 - 0.002 18.4 0.2 1.1 9.6 0.0 2.7 2 0 0 2 2 2 2 NUC130/3NT domain Nucleoporin_FG PF13634.1 CCD23711.1 - 3.8e-60 201.1 353.6 2.2e-15 56.8 33.5 9.7 1 1 8 9 9 9 9 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 CCD23711.1 - 1e-40 138.8 0.2 2.2e-40 137.7 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin autopeptidase SRF-TF PF00319.13 CCD23712.1 - 2.3e-25 87.5 0.3 2.3e-25 87.5 0.2 1.8 2 0 0 2 2 2 1 SRF-type transcription factor (DNA-binding and dimerisation domain) NDK PF00334.14 CCD23713.1 - 3.6e-57 191.9 0.0 4.1e-57 191.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Bap31 PF05529.7 CCD23714.1 - 8e-45 152.6 0.3 9.3e-45 152.4 0.2 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Anoctamin PF04547.7 CCD23714.1 - 0.0017 17.0 0.1 0.0021 16.7 0.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel GIDA_assoc_3 PF13932.1 CCD23714.1 - 0.028 14.4 1.0 0.039 14.0 0.1 1.7 2 0 0 2 2 2 0 GidA associated domain 3 AA_permease_2 PF13520.1 CCD23714.1 - 0.047 12.2 0.2 0.054 12.0 0.1 1.1 1 0 0 1 1 1 0 Amino acid permease CorA PF01544.13 CCD23715.1 - 6.3e-41 140.3 4.0 1.3e-21 76.9 0.8 3.5 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein EOS1 PF12326.3 CCD23716.1 - 1.4 8.5 5.3 3.8 7.1 3.7 1.7 1 1 0 1 1 1 0 N-glycosylation protein zf-C2H2_4 PF13894.1 CCD23717.1 - 3.2e-07 30.2 13.0 0.00044 20.3 2.3 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCD23717.1 - 2.4e-06 27.5 26.3 0.00014 21.9 2.9 3.8 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCD23717.1 - 6e-06 26.2 17.2 0.00066 19.8 2.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCD23717.1 - 0.036 14.2 10.1 1.2 9.3 1.7 3.0 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CCD23717.1 - 0.074 12.8 7.9 1.5 8.6 1.4 3.1 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 CCD23717.1 - 0.24 11.3 7.1 1.9 8.5 1.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.20 CCD23718.1 - 1.9e-37 128.8 0.9 1.9e-37 128.8 0.7 3.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23718.1 - 5.7e-18 64.9 0.3 3.5e-13 49.2 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase Kinase-like PF14531.1 CCD23718.1 - 0.00083 18.4 0.0 0.023 13.6 0.0 2.9 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 CCD23718.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Actin PF00022.14 CCD23719.1 - 6.6e-18 64.3 0.0 3.9e-16 58.4 0.0 2.8 2 1 0 2 2 2 1 Actin Seryl_tRNA_N PF02403.17 CCD23719.1 - 0.051 13.6 0.5 0.051 13.6 0.4 1.9 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain BBS2_N PF14781.1 CCD23719.1 - 0.11 12.1 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Histone PF00125.19 CCD23720.1 - 4.4e-25 87.5 0.4 8.9e-25 86.6 0.3 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DUF3812 PF12757.2 CCD23721.1 - 1.2e-15 57.6 0.4 1.2e-15 57.6 0.3 5.3 6 1 1 7 7 7 1 Protein of unknown function (DUF3812) Frag1 PF10277.4 CCD23722.1 - 1e-76 257.2 25.9 1.2e-76 256.9 18.0 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EVC2_like PF12297.3 CCD23722.1 - 0.048 12.3 0.1 0.07 11.7 0.1 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein CUE PF02845.11 CCD23723.1 - 2e-05 23.9 0.0 3.9e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 CUE domain UPF0203 PF05254.7 CCD23724.1 - 5e-30 103.1 3.5 7.1e-30 102.6 2.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 CCD23724.1 - 0.011 15.4 3.2 0.65 9.8 0.2 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UCR_hinge PF02320.11 CCD23724.1 - 0.088 12.7 2.9 0.31 11.0 2.0 1.8 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein COX6B PF02297.12 CCD23724.1 - 0.89 9.6 7.4 5.9 6.9 0.5 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb DASH_Ask1 PF08655.5 CCD23725.1 - 1.6e-27 95.1 1.8 3.3e-27 94.0 1.2 1.6 1 0 0 1 1 1 1 DASH complex subunit Ask1 F_bP_aldolase PF01116.15 CCD23726.1 - 5.7e-93 311.1 0.0 6.4e-93 310.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II ATP_sub_h PF10775.4 CCD23727.1 - 0.057 13.1 1.1 3 7.6 0.0 2.4 1 1 1 2 2 2 0 ATP synthase complex subunit h DUF2347 PF09804.4 CCD23728.1 - 1.2e-69 234.7 1.2 1.6e-69 234.3 0.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 CCD23728.1 - 3.7e-13 49.9 0.5 4.1e-10 40.0 0.0 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) Avl9 PF09794.4 CCD23728.1 - 5.6e-11 41.5 0.7 1e-09 37.3 0.5 2.6 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 CCD23728.1 - 1.1e-08 34.7 0.1 2.8e-08 33.4 0.0 1.7 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 CCD23728.1 - 0.061 13.3 0.2 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Glyco_hydro_76 PF03663.9 CCD23729.1 - 1.9e-154 514.5 22.2 2.5e-154 514.1 15.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 zf-C2H2 PF00096.21 CCD23730.1 - 0.0011 19.1 14.0 0.0015 18.7 1.7 3.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCD23730.1 - 0.006 16.8 10.2 0.018 15.3 0.3 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCD23730.1 - 0.011 16.0 1.2 0.011 16.0 0.8 4.4 4 0 0 4 4 4 0 C2H2-type zinc finger Herpes_UL45 PF05473.7 CCD23730.1 - 0.043 13.2 0.1 0.11 11.8 0.0 1.7 1 0 0 1 1 1 0 UL45 protein MAGP PF05507.6 CCD23730.1 - 2.2 8.0 6.1 1.7 8.4 1.7 2.5 2 0 0 2 2 2 0 Microfibril-associated glycoprotein (MAGP) DUF676 PF05057.9 CCD23731.1 - 2.6e-07 30.1 0.1 6.2e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CCD23731.1 - 3.4e-07 30.0 0.0 7.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 CCD23731.1 - 5.4e-05 22.4 0.1 0.00083 18.5 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 CCD23731.1 - 0.0011 18.5 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 CCD23731.1 - 0.0015 17.5 2.1 0.013 14.5 0.0 2.7 3 0 0 3 3 3 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 CCD23731.1 - 0.074 12.8 0.0 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCD23731.1 - 0.24 11.2 0.0 0.37 10.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.20 CCD23732.1 - 1.3e-15 57.7 0.0 2.6e-08 33.9 0.0 3.1 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 CCD23732.1 - 1.1e-07 31.8 0.1 2.3e-07 30.8 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCD23732.1 - 0.004 16.6 0.2 0.07 12.5 0.1 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CCD23732.1 - 0.018 14.7 0.0 1.8 8.2 0.0 2.5 2 0 0 2 2 2 0 KR domain HAD PF12710.2 CCD23732.1 - 0.095 12.8 0.1 0.23 11.5 0.1 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase NAD_binding_10 PF13460.1 CCD23732.1 - 0.12 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 NADH(P)-binding TCTP PF00838.12 CCD23733.1 - 3.4e-71 238.5 1.2 3.8e-71 238.4 0.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein TFIIA_gamma_C PF02751.9 CCD23734.1 - 9.8e-27 92.5 1.8 1.5e-26 91.8 1.3 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 CCD23734.1 - 4.2e-25 87.0 0.2 5.6e-25 86.6 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DapH_N PF08503.5 CCD23734.1 - 0.031 14.3 0.1 0.054 13.6 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrodipicolinate succinyltransferase N-terminal DWNN PF08783.6 CCD23735.1 - 8e-34 115.4 1.8 4.4e-33 113.0 0.1 2.4 2 0 0 2 2 2 1 DWNN domain U-box PF04564.10 CCD23735.1 - 1.4e-06 28.1 0.0 4.5e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 U-box domain zf-CCHC PF00098.18 CCD23735.1 - 0.00025 20.8 8.5 0.0025 17.6 1.9 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-Nse PF11789.3 CCD23735.1 - 0.00029 20.3 0.7 0.00076 18.9 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-CCHC_2 PF13696.1 CCD23735.1 - 0.0013 18.1 3.7 0.0029 17.0 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Rubredoxin PF00301.15 CCD23735.1 - 0.0062 16.3 4.1 2.7 7.9 0.0 3.4 3 0 0 3 3 3 2 Rubredoxin Zn_Tnp_IS1595 PF12760.2 CCD23735.1 - 0.039 13.7 0.4 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain SNN_cytoplasm PF09051.5 CCD23735.1 - 0.04 13.6 0.1 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Stannin cytoplasmic zf-CCHC_5 PF14787.1 CCD23735.1 - 0.05 13.0 0.3 0.05 13.0 0.2 2.7 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 CCD23735.1 - 0.072 12.8 1.2 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 Zinc knuckle TF_Zn_Ribbon PF08271.7 CCD23735.1 - 0.15 11.4 4.0 0.19 11.0 0.1 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding DUF1610 PF07754.6 CCD23735.1 - 0.51 10.5 6.3 0.13 12.4 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) TPT PF03151.11 CCD23736.1 - 1.3e-41 141.7 4.5 1.3e-41 141.7 3.1 2.3 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 CCD23736.1 - 1.2e-09 37.4 17.9 6.3e-08 31.8 3.8 2.8 2 1 0 2 2 2 2 UAA transporter family EmrE PF13536.1 CCD23736.1 - 4e-05 23.7 0.6 4e-05 23.7 0.4 3.4 3 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 CCD23736.1 - 0.00026 21.0 3.3 0.00026 21.0 2.3 3.1 4 1 0 4 4 4 2 EamA-like transporter family FixQ PF05545.6 CCD23736.1 - 0.056 13.1 0.0 0.35 10.5 0.0 2.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ DUF485 PF04341.7 CCD23736.1 - 4.4 7.0 18.9 0.33 10.7 1.2 3.6 3 0 0 3 3 3 0 Protein of unknown function, DUF485 CGI-121 PF08617.5 CCD23738.1 - 8.4e-40 136.0 2.3 9.4e-40 135.9 1.6 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 Peptidase_M32 PF02074.10 CCD23738.1 - 0.0062 15.2 0.0 0.0072 15.0 0.0 1.1 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase A_deaminase PF00962.17 CCD23739.1 - 6.9e-120 399.9 0.1 1e-119 399.3 0.0 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase MSC PF09402.5 CCD23740.1 - 1.2e-97 326.6 5.7 1.2e-97 326.6 4.0 2.8 4 0 0 4 4 4 1 Man1-Src1p-C-terminal domain HeH PF12949.2 CCD23740.1 - 2.7e-11 42.8 1.3 1.2e-10 40.6 0.9 2.2 1 0 0 1 1 1 1 HeH/LEM domain Rad52_Rad22 PF04098.10 CCD23741.1 - 1.9e-56 190.0 0.0 3.2e-56 189.3 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Ndc1_Nup PF09531.5 CCD23742.1 - 2.5e-106 356.5 17.3 3.1e-106 356.1 12.0 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup HIG_1_N PF04588.8 CCD23743.1 - 2.6e-20 71.8 1.4 3.5e-20 71.4 0.9 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Phage_prot_Gp6 PF05133.9 CCD23743.1 - 0.0083 14.7 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Phage portal protein, SPP1 Gp6-like SprA-related PF12118.3 CCD23743.1 - 0.037 13.3 0.2 0.061 12.6 0.1 1.3 1 0 0 1 1 1 0 SprA-related family DUF4094 PF13334.1 CCD23743.1 - 0.2 12.0 1.4 0.3 11.5 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) IncA PF04156.9 CCD23743.1 - 0.45 10.0 10.7 0.71 9.4 7.4 1.3 1 0 0 1 1 1 0 IncA protein M PF02370.11 CCD23743.1 - 0.46 11.0 0.1 0.46 11.0 0.0 3.4 4 0 0 4 4 4 0 M protein repeat ubiquitin PF00240.18 CCD23744.1 - 0.0074 15.6 0.0 0.025 13.9 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family AhpC-TSA PF00578.16 CCD23745.1 - 1.5e-35 121.5 0.0 4.2e-35 120.1 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CCD23745.1 - 3.8e-19 68.6 0.2 5.4e-19 68.1 0.0 1.3 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.4 CCD23745.1 - 7.9e-12 44.6 0.6 1.6e-11 43.6 0.1 1.8 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin Homeobox PF00046.24 CCD23746.1 - 2e-16 59.3 4.6 7.2e-16 57.5 3.2 2.0 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCD23746.1 - 0.034 13.8 0.7 0.12 12.0 0.1 2.3 2 0 0 2 2 2 0 Homeobox KN domain Ribosomal_S13 PF00416.17 CCD23747.1 - 2.1e-42 143.8 1.9 2.5e-42 143.6 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CCD23747.1 - 0.0016 17.0 0.0 0.0027 16.3 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Ribosomal_L4 PF00573.17 CCD23748.1 - 1.2e-44 152.0 0.0 1.5e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S17e PF00833.13 CCD23749.1 - 2.2e-56 188.8 0.2 2.6e-56 188.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 Nse5 PF08691.5 CCD23750.1 - 1.8e-121 406.1 17.7 2.2e-121 405.8 12.3 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Pribosyltran PF00156.22 CCD23751.1 - 1e-17 64.0 0.0 1.5e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCD23751.1 - 0.0048 16.1 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UDG PF03167.14 CCD23752.1 - 5e-27 94.2 0.1 7.8e-27 93.6 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RE_MamI PF09567.5 CCD23752.1 - 0.036 13.1 0.0 0.048 12.7 0.0 1.2 1 0 0 1 1 1 0 MamI restriction endonuclease tRNA_synt_1c_R1 PF04558.10 CCD23752.1 - 0.063 12.8 1.5 0.11 11.9 1.0 1.4 1 0 0 1 1 1 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 OST3_OST6 PF04756.8 CCD23754.1 - 4.4e-23 81.6 5.8 7.4e-23 80.8 4.0 1.3 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 CCD23754.1 - 0.0043 16.6 0.0 0.0096 15.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin NOB1_Zn_bind PF08772.6 CCD23754.1 - 0.031 14.1 0.1 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like TPT PF03151.11 CCD23755.1 - 5.6e-08 32.5 23.5 2.8e-05 23.8 5.7 3.0 3 0 0 3 3 3 2 Triose-phosphate Transporter family EamA PF00892.15 CCD23755.1 - 1.2e-06 28.6 35.1 2.4e-05 24.3 4.2 3.5 3 1 0 3 3 3 2 EamA-like transporter family DUF914 PF06027.7 CCD23755.1 - 8.7e-05 21.5 7.0 8.7e-05 21.5 4.8 1.9 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 CCD23755.1 - 0.00015 20.7 11.7 0.00015 20.7 8.1 1.5 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.1 CCD23755.1 - 0.00026 21.1 20.6 0.0068 16.5 0.7 3.2 3 0 0 3 3 3 2 Multidrug resistance efflux transporter RRM_1 PF00076.17 CCD23756.1 - 0.081 12.5 0.7 2.7 7.6 0.0 2.4 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.23 CCD23757.1 - 5.8e-39 133.5 0.2 1.1e-38 132.7 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Methyltransf_11 PF08241.7 CCD23758.1 - 6.2e-11 42.6 0.0 1.2e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCD23758.1 - 2.9e-06 26.9 0.0 4.5e-06 26.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCD23758.1 - 3.3e-06 26.9 0.0 2.2e-05 24.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCD23758.1 - 1.3e-05 25.6 0.1 1.3e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD23758.1 - 0.0002 21.6 0.0 0.0004 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD23758.1 - 0.0018 18.8 0.0 0.0034 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCD23758.1 - 0.01 14.5 1.0 0.015 13.9 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1698) TehB PF03848.9 CCD23758.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB RNA_pol_Rpc4 PF05132.9 CCD23758.1 - 0.35 10.8 2.4 0.64 10.0 1.6 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 Atrophin-1 PF03154.10 CCD23758.1 - 0.58 8.2 5.3 0.75 7.8 3.7 1.0 1 0 0 1 1 1 0 Atrophin-1 family UBX PF00789.15 CCD23759.1 - 2.6e-13 49.8 0.0 1.4e-11 44.2 0.0 2.9 2 1 0 2 2 2 1 UBX domain UBA_4 PF14555.1 CCD23759.1 - 2e-11 43.2 3.4 6.6e-11 41.5 0.1 2.8 3 0 0 3 3 3 1 UBA-like domain EMP24_GP25L PF01105.19 CCD23760.1 - 4.4e-44 150.4 0.0 4.9e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DASH_Dad2 PF08654.5 CCD23760.1 - 0.0061 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dad2 EzrA PF06160.7 CCD23760.1 - 0.027 12.6 0.8 0.035 12.3 0.5 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Rad33 PF08730.5 CCD23761.1 - 9.9e-30 103.2 4.8 3.9e-20 71.9 0.6 2.1 1 1 1 2 2 2 2 Rad33 SpoVIF PF14069.1 CCD23761.1 - 0.1 12.3 0.3 0.3 10.8 0.1 2.0 2 0 0 2 2 2 0 Stage VI sporulation protein F Spt5-NGN PF03439.8 CCD23762.1 - 1.5e-20 72.6 0.0 5.3e-20 70.9 0.0 2.0 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 CCD23762.1 - 2.2e-18 66.6 11.8 2.2e-18 66.6 8.2 3.4 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 CCD23762.1 - 5.4e-16 57.5 9.1 0.0012 18.4 0.0 4.8 4 0 0 4 4 4 4 KOW motif CTD PF12815.2 CCD23762.1 - 0.00013 22.3 45.8 0.00014 22.2 16.6 3.3 2 1 1 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 SPT6_acidic PF14632.1 CCD23762.1 - 0.0032 17.6 17.3 0.0032 17.6 12.0 2.8 1 1 1 2 2 2 1 Acidic N-terminal SPT6 SDA1 PF05285.7 CCD23762.1 - 0.049 12.9 32.0 0.097 11.9 22.2 1.5 1 0 0 1 1 1 0 SDA1 Nucleo_P87 PF07267.6 CCD23762.1 - 4.8 5.7 25.0 11 4.5 17.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Daxx PF03344.10 CCD23762.1 - 6.1 5.1 39.0 11 4.3 27.1 1.4 1 0 0 1 1 1 0 Daxx Family Ribosomal_L33 PF00471.15 CCD23763.1 - 0.00011 22.3 0.0 0.001 19.2 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L33 eIF3g PF12353.3 CCD23764.1 - 3.1e-43 146.7 1.8 4.6e-43 146.1 1.3 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CCD23764.1 - 5e-12 45.2 0.0 8.8e-12 44.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD23764.1 - 2.6e-08 33.6 0.0 4.6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD23764.1 - 5.4e-08 32.5 0.0 9.4e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PX PF00787.19 CCD23765.1 - 4.9e-14 52.0 1.4 2.5e-13 49.8 0.1 2.6 2 0 0 2 2 2 1 PX domain Sterol_MT_C PF08498.5 CCD23766.1 - 6.5e-31 106.0 1.1 9.3e-31 105.5 0.8 1.2 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 CCD23766.1 - 1.5e-22 79.7 0.1 2.6e-22 79.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCD23766.1 - 1.1e-19 70.7 0.0 2.1e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCD23766.1 - 3.7e-14 52.7 0.0 6.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCD23766.1 - 6.1e-13 49.0 0.0 1.6e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCD23766.1 - 1.1e-12 47.5 0.4 1.5e-12 47.2 0.3 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 CCD23766.1 - 3.6e-11 43.6 0.0 1.2e-10 41.9 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD23766.1 - 1.3e-09 38.2 0.0 4.8e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCD23766.1 - 4.9e-09 35.6 0.0 7.4e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CCD23766.1 - 5.1e-08 32.9 0.0 1.2e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CCD23766.1 - 2.8e-06 26.9 0.2 5.6e-06 26.0 0.2 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_3 PF01596.12 CCD23766.1 - 0.0012 17.9 0.1 0.0021 17.1 0.1 1.4 1 0 0 1 1 1 1 O-methyltransferase UPF0020 PF01170.13 CCD23766.1 - 0.0013 18.3 0.0 0.0029 17.2 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 CCD23766.1 - 0.0021 18.8 0.0 0.0049 17.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CCD23766.1 - 0.0022 17.5 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CCD23766.1 - 0.0069 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 CCD23766.1 - 0.011 14.8 0.0 0.022 13.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 CCD23766.1 - 0.023 13.7 0.0 0.097 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase MetW PF07021.7 CCD23766.1 - 0.032 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 CCD23766.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 CCD23766.1 - 0.13 11.8 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase PAP1 PF08601.5 CCD23767.1 - 3.4e-53 181.5 36.9 3.4e-53 181.5 25.6 3.7 1 1 1 2 2 2 1 Transcription factor PAP1 bZIP_1 PF00170.16 CCD23767.1 - 1.9e-06 27.7 14.6 7.2e-06 25.8 10.1 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCD23767.1 - 0.016 15.0 14.0 0.016 15.0 9.7 2.2 2 1 0 2 2 2 0 Basic region leucine zipper cEGF PF12662.2 CCD23769.1 - 5.1 6.8 9.2 0.78 9.4 1.8 2.3 2 0 0 2 2 2 0 Complement Clr-like EGF-like Ribosomal_L11_N PF03946.9 CCD23770.1 - 1.5e-17 62.7 0.8 3.8e-17 61.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CCD23770.1 - 1.1e-11 44.6 1.6 1.7e-11 44.1 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain Mak10 PF04112.8 CCD23771.1 - 1e-42 145.1 3.0 3.4e-42 143.5 0.2 2.3 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase DUF3019 PF11456.3 CCD23771.1 - 0.027 14.7 1.2 0.078 13.3 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3019) HHH_5 PF14520.1 CCD23771.1 - 0.13 12.4 0.1 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain AFG1_ATPase PF03969.11 CCD23772.1 - 9.4e-77 258.2 0.0 4.2e-54 183.7 0.0 3.2 2 1 1 3 3 3 3 AFG1-like ATPase AAA PF00004.24 CCD23772.1 - 0.00011 22.3 0.0 0.00031 20.9 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 CCD23772.1 - 0.0027 17.4 0.1 0.017 14.8 0.0 2.4 1 1 1 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 CCD23772.1 - 0.0042 17.1 0.3 0.17 11.8 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 CCD23772.1 - 0.024 14.3 0.0 0.19 11.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.13 CCD23772.1 - 0.041 13.5 0.1 0.074 12.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein RNA_helicase PF00910.17 CCD23772.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 CCD23772.1 - 0.068 12.2 0.0 2.6 7.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 CCD23772.1 - 0.088 12.9 0.2 0.39 10.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain Ribosomal_L2_C PF03947.13 CCD23773.1 - 3e-48 162.9 1.9 6.3e-48 161.8 1.3 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCD23773.1 - 6.3e-25 86.9 0.2 1.9e-24 85.4 0.2 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Carn_acyltransf PF00755.15 CCD23774.1 - 2.8e-168 560.7 6.5 3.3e-168 560.4 4.5 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase ADH_zinc_N_2 PF13602.1 CCD23775.1 - 3.2e-11 44.1 0.0 5.4e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCD23775.1 - 3.2e-05 23.4 0.0 5.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PINIT PF14324.1 CCD23776.1 - 2.2e-32 112.0 0.3 2.2e-32 112.0 0.2 2.6 3 0 0 3 3 3 1 PINIT domain zf-MIZ PF02891.15 CCD23776.1 - 1.7e-20 72.2 7.2 3.2e-20 71.3 5.0 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 CCD23776.1 - 2.8e-10 39.4 0.1 5.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 CCD23776.1 - 0.00039 19.8 1.4 0.00086 18.7 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit WIYLD PF10440.4 CCD23776.1 - 0.009 15.9 1.8 5.4 7.0 0.0 3.0 3 0 0 3 3 3 2 Ubiquitin-binding WIYLD domain zf-RING_UBOX PF13445.1 CCD23776.1 - 0.1 12.3 2.1 0.48 10.1 1.5 2.3 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCD23776.1 - 1.2 9.1 3.8 2.1 8.2 2.6 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING rve PF00665.21 CCD23777.1 - 2.7e-08 33.9 0.0 3.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain Proteasome PF00227.21 CCD23778.1 - 3e-48 163.6 0.0 4.2e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CCD23778.1 - 4.6e-15 54.5 0.1 1.1e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal Dna2 PF08696.6 CCD23778.1 - 0.03 13.6 0.2 0.045 13.0 0.1 1.2 1 0 0 1 1 1 0 DNA replication factor Dna2 LSM PF01423.17 CCD23780.1 - 5.8e-14 51.3 0.0 6.7e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain Xpo1 PF08389.7 CCD23781.1 - 8.6e-25 87.3 1.2 8.6e-25 87.3 0.8 3.8 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 CCD23781.1 - 6.7e-05 22.7 1.6 0.0013 18.6 0.8 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Choline_transpo PF04515.7 CCD23782.1 - 2e-95 319.3 17.7 2e-95 319.3 12.3 1.7 2 0 0 2 2 2 1 Plasma-membrane choline transporter ESSS PF10183.4 CCD23782.1 - 8.1 6.9 8.6 16 5.9 0.0 3.8 4 0 0 4 4 4 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ABC2_membrane PF01061.19 CCD23783.1 - 1.2e-88 295.7 50.9 4.7e-46 156.6 13.3 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 CCD23783.1 - 9.1e-41 137.7 8.4 1.2e-36 124.4 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 CCD23783.1 - 2.1e-38 131.6 0.0 1.3e-18 67.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 CCD23783.1 - 1.5e-25 89.1 0.1 4.7e-25 87.4 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CCD23783.1 - 1.2e-08 34.5 0.0 5.8e-05 22.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCD23783.1 - 6.4e-07 29.5 0.3 5.1e-05 23.3 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CCD23783.1 - 2.6e-05 23.4 0.0 0.0008 18.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 CCD23783.1 - 3.5e-05 23.3 1.8 0.01 15.2 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 CCD23783.1 - 8.5e-05 22.2 0.1 0.32 10.7 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_18 PF13238.1 CCD23783.1 - 0.00016 22.0 0.4 0.1 12.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 CCD23783.1 - 0.00027 20.4 0.5 0.0049 16.3 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 CCD23783.1 - 0.0012 19.1 0.1 0.065 13.5 0.0 3.1 3 0 0 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.2 CCD23783.1 - 0.0021 17.1 48.9 0.014 14.4 10.9 3.5 2 2 1 3 3 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 CCD23783.1 - 0.0022 18.0 0.1 0.09 12.7 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA_28 PF13521.1 CCD23783.1 - 0.0023 17.9 0.5 0.062 13.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCD23783.1 - 0.0023 17.5 0.3 2.3 7.8 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_33 PF13671.1 CCD23783.1 - 0.0031 17.3 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCD23783.1 - 0.0033 17.5 0.1 0.49 10.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CCD23783.1 - 0.0041 16.3 3.8 0.015 14.5 0.0 3.1 3 1 0 3 3 2 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 CCD23783.1 - 0.0054 16.3 0.4 0.7 9.5 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 CCD23783.1 - 0.0079 17.0 0.0 1.2 9.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 CCD23783.1 - 0.052 12.0 0.3 11 4.3 0.0 3.3 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 CCD23783.1 - 0.1 12.0 0.4 1.8 8.0 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 CCD23783.1 - 0.11 12.2 0.4 9.2 5.9 0.1 2.8 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.1 CCD23783.1 - 0.16 11.5 0.3 5.7 6.4 0.2 2.4 2 0 0 2 2 2 0 AAA domain DUF2775 PF10950.3 CCD23783.1 - 0.23 11.7 3.1 0.22 11.7 0.5 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF2775) ISN1 PF06437.6 CCD23784.1 - 5.3e-180 598.4 0.0 6.3e-180 598.2 0.0 1.1 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF2569 PF10754.4 CCD23785.1 - 0.35 11.0 7.5 0.67 10.1 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) RNA_pol_Rpb2_6 PF00562.23 CCD23786.1 - 2.7e-126 421.4 0.5 3.9e-126 420.9 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCD23786.1 - 1.9e-72 242.4 0.1 3e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCD23786.1 - 3e-51 173.5 0.0 5.9e-51 172.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCD23786.1 - 5.4e-31 106.7 0.0 1.3e-30 105.4 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CCD23786.1 - 3.7e-28 97.1 2.0 5.3e-28 96.6 0.3 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CCD23786.1 - 5.9e-22 77.1 0.1 1.8e-21 75.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CCD23786.1 - 3.1e-18 65.4 1.3 8.6e-18 64.0 0.9 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.2 CCD23786.1 - 0.15 11.9 0.1 0.28 11.0 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_L13 PF00572.13 CCD23787.1 - 3e-44 150.1 0.1 3.8e-44 149.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 MDM31_MDM32 PF08118.6 CCD23788.1 - 4.7e-41 140.8 20.3 2.1e-31 108.9 4.0 4.0 2 1 2 4 4 4 4 Yeast mitochondrial distribution and morphology (MDM) proteins G-patch_2 PF12656.2 CCD23789.1 - 2.2e-21 75.5 0.4 2.2e-21 75.5 0.3 2.5 2 1 0 2 2 2 1 DExH-box splicing factor binding site FRG2 PF15315.1 CCD23789.1 - 0.28 11.1 6.5 4.4 7.2 0.4 2.2 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 Glyco_transf_22 PF03901.12 CCD23790.1 - 6.2e-71 239.5 34.1 7.5e-71 239.3 23.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family CBFD_NFYB_HMF PF00808.18 CCD23791.1 - 1.1e-11 44.6 0.3 1.6e-11 44.0 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2960 PF11173.3 CCD23791.1 - 0.013 15.7 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) ICAT PF06384.6 CCD23791.1 - 0.051 13.3 0.2 0.2 11.4 0.0 2.0 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT IZUMO PF15005.1 CCD23792.1 - 0.013 15.5 0.1 0.025 14.6 0.1 1.4 1 0 0 1 1 1 0 Izumo sperm-egg fusion IZUMO PF15005.1 CCD23793.1 - 0.015 15.3 0.1 0.026 14.5 0.1 1.3 1 0 0 1 1 1 0 Izumo sperm-egg fusion ASFV_p27 PF06556.6 CCD23793.1 - 0.14 12.0 2.7 0.31 10.9 1.1 2.2 1 1 1 2 2 2 0 IAP-like protein p27 C-terminus Utp12 PF04003.7 CCD23794.1 - 7.8e-18 64.4 3.4 7.8e-18 64.4 2.4 2.0 2 0 0 2 2 2 1 Dip2/Utp12 Family RAB3GAP2_N PF14655.1 CCD23794.1 - 0.013 14.5 3.5 0.99 8.3 0.4 2.2 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PRA-CH PF01502.13 CCD23794.1 - 0.089 12.4 0.6 0.75 9.4 0.0 2.5 2 0 0 2 2 2 0 Phosphoribosyl-AMP cyclohydrolase AAA PF00004.24 CCD23795.1 - 0.00012 22.2 0.1 0.0011 19.1 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) TPK_catalytic PF04263.11 CCD23796.1 - 7.7e-19 67.4 0.2 4.9e-15 55.1 0.1 2.3 2 0 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 CCD23796.1 - 7e-14 51.2 0.5 1.7e-13 50.0 0.3 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CoA_binding PF02629.14 CCD23797.1 - 1.3e-25 89.7 2.7 3.3e-25 88.4 0.3 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 CCD23797.1 - 1.1e-23 83.5 0.5 2.1e-23 82.6 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CCD23797.1 - 6.2e-06 25.8 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CCD23797.1 - 0.00014 22.0 0.0 0.00096 19.3 0.0 2.1 2 0 0 2 2 2 1 CoA binding domain IlvN PF07991.7 CCD23797.1 - 0.019 14.3 0.1 0.11 11.8 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Toprim_Crpt PF13342.1 CCD23797.1 - 0.039 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase Actin PF00022.14 CCD23798.1 - 1.4e-23 82.9 0.0 1e-17 63.6 0.0 3.7 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CCD23798.1 - 0.0051 15.4 0.0 0.3 9.6 0.0 2.5 2 0 0 2 2 2 2 MreB/Mbl protein HSF_DNA-bind PF00447.12 CCD23799.1 - 2e-35 121.0 3.9 9.6e-35 118.8 2.7 2.3 1 0 0 1 1 1 1 HSF-type DNA-binding UBA PF00627.26 CCD23800.1 - 9.2e-09 34.8 0.4 2.4e-08 33.5 0.1 1.9 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 CCD23800.1 - 0.0061 16.0 0.0 0.017 14.6 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain Metallophos PF00149.23 CCD23801.1 - 1.9e-08 33.9 2.2 4.3e-07 29.5 0.2 2.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Iso_dh PF00180.15 CCD23802.1 - 2.9e-104 348.7 0.0 3.5e-104 348.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RhoGAP PF00620.22 CCD23803.1 - 4.8e-34 117.1 0.4 1.5e-33 115.5 0.3 1.8 1 1 0 1 1 1 1 RhoGAP domain GTP_EFTU PF00009.22 CCD23804.1 - 8e-64 214.5 0.2 1e-63 214.2 0.2 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CCD23804.1 - 6.2e-19 67.6 0.0 1.7e-18 66.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 CCD23804.1 - 8.4e-06 25.7 0.1 1.7e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCD23804.1 - 0.035 14.5 0.2 0.19 12.2 0.1 2.2 2 0 0 2 2 2 0 Miro-like protein Vps5 PF09325.5 CCD23805.1 - 3.3e-10 39.6 4.1 5.9e-10 38.7 2.8 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CCD23805.1 - 8.2e-09 35.2 0.4 1.7e-08 34.2 0.2 1.5 1 0 0 1 1 1 1 PX domain HAD_2 PF13419.1 CCD23806.1 - 1.4e-11 44.9 0.0 1.6e-10 41.4 0.0 2.0 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCD23806.1 - 5.5e-10 38.8 0.0 9.4e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCD23806.1 - 5.7e-10 39.9 0.0 5.3e-07 30.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCD23806.1 - 0.0018 18.4 0.0 0.004 17.3 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCD23806.1 - 0.0025 17.4 2.2 0.38 10.2 0.1 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 CCD23806.1 - 0.02 14.2 0.0 0.44 9.8 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Ribosomal_60s PF00428.14 CCD23807.1 - 5.4e-24 84.4 12.1 6.4e-24 84.1 8.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3138 PF11336.3 CCD23807.1 - 0.12 10.5 1.2 0.12 10.5 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Herpes_capsid PF06112.6 CCD23807.1 - 0.2 11.7 1.4 0.24 11.4 0.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Mito_carr PF00153.22 CCD23808.1 - 1.5e-63 210.5 0.3 4e-21 74.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldo_ket_red PF00248.16 CCD23809.1 - 2.8e-64 216.6 0.0 3.2e-64 216.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.7 CCD23809.1 - 0.042 13.2 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Afi1 PF07792.7 CCD23810.1 - 3.7e-39 134.0 0.1 3.7e-39 134.0 0.0 2.4 3 0 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 CCD23810.1 - 3.3e-25 87.9 0.7 9.3e-25 86.5 0.5 1.8 1 0 0 1 1 1 1 Stabilization of polarity axis AIRC PF00731.15 CCD23811.1 - 2.1e-63 212.0 0.8 5e-63 210.8 0.4 1.7 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.17 CCD23811.1 - 1.7e-60 203.2 0.0 2.6e-60 202.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 CCD23811.1 - 2.4e-08 33.9 0.0 4.8e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CCD23811.1 - 3e-05 23.3 0.0 5.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.14 CCD23811.1 - 0.00055 19.1 0.0 0.0015 17.7 0.0 1.7 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 CCD23811.1 - 0.0019 18.1 0.1 0.0038 17.1 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain Dala_Dala_lig_C PF07478.8 CCD23811.1 - 0.0035 16.7 0.0 0.03 13.7 0.0 2.2 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CCD23811.1 - 0.026 14.3 0.0 0.1 12.4 0.0 2.1 2 1 0 2 2 2 0 ATP-grasp domain CoA_binding_2 PF13380.1 CCD23811.1 - 0.086 13.0 0.7 58 3.8 0.0 3.4 2 1 1 3 3 3 0 CoA binding domain RhoGAP PF00620.22 CCD23812.1 - 1.5e-41 141.5 0.7 3.9e-41 140.1 0.5 1.7 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 CCD23812.1 - 9.1e-11 41.6 32.1 3.4e-06 27.0 8.3 2.8 3 0 0 3 3 3 2 LIM domain Lipase_GDSL_2 PF13472.1 CCD23813.1 - 9.9e-21 74.6 0.0 1.1e-20 74.4 0.0 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CCD23813.1 - 4.7e-19 69.1 0.0 5.5e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase BCS1_N PF08740.6 CCD23814.1 - 6.7e-48 162.7 0.0 1.1e-47 162.0 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CCD23814.1 - 1.8e-21 76.7 0.0 4.5e-21 75.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCD23814.1 - 1.7e-06 28.8 0.0 7.5e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCD23814.1 - 0.00042 20.6 0.0 0.0032 17.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCD23814.1 - 0.00046 19.3 0.0 0.0029 16.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 CCD23814.1 - 0.00047 19.1 0.0 0.00077 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_21 PF13304.1 CCD23814.1 - 0.00051 20.0 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCD23814.1 - 0.001 18.9 0.0 0.0017 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCD23814.1 - 0.0017 18.4 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCD23814.1 - 0.0023 18.0 0.0 0.0056 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CCD23814.1 - 0.0033 17.0 0.0 0.24 11.0 0.0 2.9 2 1 0 2 2 2 1 NACHT domain AAA_5 PF07728.9 CCD23814.1 - 0.004 16.8 0.0 0.011 15.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CCD23814.1 - 0.0041 17.0 0.0 0.0088 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 CCD23814.1 - 0.0056 16.0 0.0 0.0088 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCD23814.1 - 0.0071 15.4 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 CCD23814.1 - 0.016 15.4 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_19 PF13245.1 CCD23814.1 - 0.019 14.7 0.0 0.057 13.1 0.0 1.8 1 1 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 CCD23814.1 - 0.02 15.0 0.0 0.08 13.1 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_24 PF13479.1 CCD23814.1 - 0.023 14.2 0.1 0.053 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CCD23814.1 - 0.027 14.1 0.0 0.068 12.8 0.0 1.7 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 CCD23814.1 - 0.028 13.9 0.0 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.1 CCD23814.1 - 0.033 13.7 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CCD23814.1 - 0.054 12.6 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC Gram_pos_anchor PF00746.16 CCD23814.1 - 0.055 13.2 0.4 0.21 11.4 0.3 1.9 2 0 0 2 2 2 0 Gram positive anchor Miro PF08477.8 CCD23814.1 - 0.061 13.8 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 CCD23814.1 - 0.082 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CCD23814.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain COQ7 PF03232.8 CCD23815.1 - 2.6e-73 245.1 0.1 3.2e-73 244.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 CCD23815.1 - 0.04 14.2 0.0 0.094 13.0 0.0 1.7 1 1 0 1 1 1 0 Rubrerythrin GA PF01468.12 CCD23815.1 - 0.069 13.3 0.1 0.18 11.9 0.1 1.7 1 0 0 1 1 1 0 GA module UCH PF00443.24 CCD23816.1 - 1.6e-61 207.8 0.1 6e-61 205.9 0.0 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 CCD23816.1 - 4.7e-45 150.8 6.2 1.3e-21 75.7 0.3 5.0 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 CCD23816.1 - 2.1e-12 47.1 0.3 4.4e-05 23.0 0.1 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Retrotrans_gag PF03732.12 CCD23817.1 - 6.6e-05 22.9 0.1 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CCD23817.1 - 0.002 17.9 6.0 0.0038 17.0 4.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CCD23817.1 - 0.077 12.7 3.2 0.16 11.7 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle RVT_1 PF00078.22 CCD23818.1 - 3.9e-26 91.7 0.1 7.5e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCD23818.1 - 4.5e-19 68.7 0.0 1.5e-18 67.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Peptidase_A2B PF12384.3 CCD23818.1 - 1.8e-17 63.2 0.1 4.1e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.1 CCD23818.1 - 7.6e-05 23.1 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CCD23818.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.5 CCD23818.1 - 0.0027 17.0 2.0 0.066 12.6 0.2 2.9 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Profilin PF00235.14 CCD23819.1 - 1.5e-41 141.2 0.0 1.7e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Profilin Leo1 PF04004.8 CCD23820.1 - 3.4e-46 157.0 0.1 3.4e-46 157.0 0.1 3.4 3 1 0 3 3 3 1 Leo1-like protein MDH PF02315.11 CCD23820.1 - 3.1 7.7 5.0 5.5 6.9 0.7 2.4 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit Aldo_ket_red PF00248.16 CCD23821.1 - 1.3e-55 188.2 0.0 1.5e-55 187.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BHD_3 PF10405.4 CCD23821.1 - 0.014 15.0 0.0 0.038 13.6 0.0 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 3 TLD PF07534.11 CCD23822.1 - 9.8e-27 93.6 0.8 1.8e-25 89.5 0.5 2.5 1 1 0 1 1 1 1 TLD RNA_pol_Rpb1_5 PF04998.12 CCD23823.1 - 4.4e-97 324.6 0.1 7e-97 324.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CCD23823.1 - 5.3e-82 275.7 0.0 8e-82 275.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CCD23823.1 - 3.9e-70 235.0 0.1 9.3e-70 233.8 0.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CCD23823.1 - 2.5e-39 134.5 0.0 6.2e-39 133.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CCD23823.1 - 4.3e-31 106.8 0.1 1.2e-30 105.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Peptidase_M18 PF02127.10 CCD23824.1 - 3.5e-173 576.0 0.1 4.1e-173 575.8 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CCD23824.1 - 4.9e-09 35.3 0.0 3.7e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase EMP24_GP25L PF01105.19 CCD23825.1 - 9.1e-48 162.3 3.9 1e-47 162.1 2.7 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.1 CCD23825.1 - 0.0083 16.5 0.0 0.014 15.8 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) DUF148 PF02520.12 CCD23825.1 - 0.068 12.9 1.0 0.14 11.9 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF2636 PF11120.3 CCD23825.1 - 0.16 11.5 0.6 0.27 10.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2636) STE2 PF02116.10 CCD23826.1 - 0.015 14.3 0.5 0.023 13.7 0.3 1.2 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR Septin PF00735.13 CCD23827.1 - 4e-115 383.6 0.0 5.7e-115 383.1 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCD23827.1 - 7.7e-06 25.8 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCD23827.1 - 9.5e-05 21.6 0.1 0.00043 19.4 0.1 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCD23827.1 - 0.00054 20.1 0.0 0.0022 18.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 CCD23827.1 - 0.0013 18.1 0.4 0.025 14.0 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CCD23827.1 - 0.0019 18.7 0.0 0.0074 16.7 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 CCD23827.1 - 0.003 17.0 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 CCD23827.1 - 0.0032 17.3 3.9 2.7 7.7 0.0 3.2 2 1 1 3 3 3 1 Dynamin family AAA_24 PF13479.1 CCD23827.1 - 0.0072 15.9 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCD23827.1 - 0.0081 16.1 0.0 0.047 13.6 0.0 2.1 1 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 CCD23827.1 - 0.011 15.9 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 CCD23827.1 - 0.012 15.3 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain IIGP PF05049.8 CCD23827.1 - 0.013 14.3 0.3 0.1 11.3 0.1 2.2 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) DUF3987 PF13148.1 CCD23827.1 - 0.016 13.8 0.2 1.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) AIG1 PF04548.11 CCD23827.1 - 0.028 13.5 0.0 0.063 12.3 0.0 1.6 1 0 0 1 1 1 0 AIG1 family AAA_10 PF12846.2 CCD23827.1 - 0.037 13.4 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Pox_A32 PF04665.7 CCD23827.1 - 0.039 13.2 0.1 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein ABC_tran PF00005.22 CCD23827.1 - 0.043 14.1 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_33 PF13671.1 CCD23827.1 - 0.044 13.6 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 CCD23827.1 - 0.058 12.5 0.0 0.26 10.3 0.0 1.9 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CCD23827.1 - 0.061 12.8 2.2 0.14 11.6 0.2 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CCD23827.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Pyr_redox_2 PF07992.9 CCD23828.1 - 3.8e-27 95.4 0.0 7e-27 94.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCD23828.1 - 3e-18 66.0 0.1 1.3e-15 57.5 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCD23828.1 - 1.3e-10 41.7 0.0 5.1e-07 29.9 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCD23828.1 - 1.1e-06 27.8 0.2 0.45 9.3 0.1 4.1 4 0 0 4 4 4 2 Glucose inhibited division protein A DAO PF01266.19 CCD23828.1 - 4.3e-05 22.5 1.4 0.23 10.3 0.0 3.8 3 1 1 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 CCD23828.1 - 0.00015 21.9 0.0 0.02 15.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 CCD23828.1 - 0.00026 21.1 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 CCD23828.1 - 0.00027 20.1 0.2 0.0037 16.4 0.0 2.3 2 1 1 3 3 3 1 Thi4 family K_oxygenase PF13434.1 CCD23828.1 - 0.0018 17.2 0.0 0.23 10.3 0.0 3.3 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CCD23828.1 - 0.0028 17.6 0.1 0.24 11.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCD23828.1 - 0.009 14.9 3.3 0.88 8.3 0.2 3.1 2 2 0 4 4 4 1 FAD binding domain FAD_binding_3 PF01494.14 CCD23828.1 - 0.018 14.1 0.2 4.7 6.1 0.0 2.6 2 1 1 3 3 3 0 FAD binding domain NAD_binding_9 PF13454.1 CCD23828.1 - 0.042 13.6 0.1 2.8 7.6 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 CCD23828.1 - 0.047 12.1 0.4 2.4 6.5 0.1 2.8 2 1 1 3 3 3 0 HI0933-like protein FAD_oxidored PF12831.2 CCD23828.1 - 0.076 12.0 0.0 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 CCD23828.1 - 0.12 12.0 0.2 10 5.8 0.2 2.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PX PF00787.19 CCD23829.1 - 1.2e-14 54.1 0.0 1.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 PX domain Pkinase PF00069.20 CCD23831.1 - 1.2e-72 244.2 0.0 1.8e-72 243.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23831.1 - 3.6e-52 176.9 0.0 5.7e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD23831.1 - 2.9e-07 29.7 0.1 7.4e-06 25.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF2477 PF10631.4 CCD23831.1 - 0.032 14.4 2.0 0.11 12.7 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) ATP-synt_S1 PF05827.7 CCD23832.1 - 5.4e-49 166.9 0.0 8.1e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) PGP_phosphatase PF09419.5 CCD23833.1 - 1.2e-69 232.9 0.0 1.5e-69 232.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 CCD23833.1 - 0.048 13.3 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase PF00702.21 CCD23833.1 - 0.061 13.7 0.1 0.14 12.5 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sec23_trunk PF04811.10 CCD23834.1 - 6.5e-54 182.8 0.0 1.1e-53 182.1 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCD23834.1 - 8.1e-20 70.1 0.2 1.7e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCD23834.1 - 1.2e-11 44.9 0.2 4.5e-11 43.1 0.0 2.2 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCD23834.1 - 2.6e-11 42.8 4.4 3.2e-11 42.5 2.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCD23834.1 - 0.0019 17.8 0.0 0.0053 16.4 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat Sugar_tr PF00083.19 CCD23835.1 - 1.5e-165 551.1 37.3 2.1e-165 550.7 25.9 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD23835.1 - 1.2e-33 116.3 41.4 7.4e-31 107.1 18.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCD23836.1 - 1.1e-172 574.7 34.7 1.2e-172 574.5 24.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD23836.1 - 2.9e-25 88.7 22.3 2.9e-25 88.7 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2178 PF09946.4 CCD23836.1 - 0.12 12.1 5.1 6.3 6.5 1.4 2.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) tRNA-synt_1d PF00750.14 CCD23837.1 - 8.3e-105 350.4 4.3 1.1e-104 350.0 2.9 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CCD23837.1 - 7.6e-30 103.3 0.5 1.8e-28 98.8 0.1 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CCD23837.1 - 2e-07 31.4 0.1 2.1e-06 28.1 0.0 2.7 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain ING PF12998.2 CCD23838.1 - 1.6e-20 73.3 4.9 1.6e-20 73.3 3.4 1.7 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CCD23838.1 - 3.2e-10 39.5 8.7 6.2e-10 38.6 6.0 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CCD23838.1 - 0.0067 16.5 0.2 0.019 15.0 0.1 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain Attractin PF08037.6 CCD23838.1 - 0.048 13.4 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 Attractin family 4HB_MCP_1 PF12729.2 CCD23838.1 - 0.062 12.6 3.0 0.1 11.9 2.1 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction zf-C4_Topoisom PF01396.14 CCD23838.1 - 5.1 6.6 8.4 12 5.5 0.5 2.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Gar1 PF04410.9 CCD23839.1 - 8.3e-43 145.5 6.6 4.4e-42 143.1 4.6 1.9 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region Xpo1 PF08389.7 CCD23840.1 - 0.00052 19.9 2.2 0.03 14.2 1.5 3.4 1 1 0 1 1 1 1 Exportin 1-like protein Brix PF04427.13 CCD23841.1 - 8.3e-42 143.0 3.1 1.3e-41 142.3 2.1 1.3 1 0 0 1 1 1 1 Brix domain Pex19 PF04614.7 CCD23841.1 - 0.058 13.0 4.4 0.1 12.2 3.0 1.4 1 0 0 1 1 1 0 Pex19 protein family SBDS PF01172.13 CCD23842.1 - 5.8e-17 61.2 0.1 8.1e-17 60.8 0.1 1.2 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein RRM_1 PF00076.17 CCD23843.1 - 4.7e-43 144.6 0.0 6e-15 54.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD23843.1 - 3.5e-27 94.1 0.0 4.8e-10 39.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD23843.1 - 9e-16 57.4 0.0 5.3e-08 32.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCD23843.1 - 0.003 17.2 0.1 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CCD23843.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif C2 PF00168.25 CCD23843.1 - 0.049 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 C2 domain STE PF02200.11 CCD23844.1 - 1.6e-33 115.1 1.0 3e-33 114.2 0.7 1.4 1 0 0 1 1 1 1 STE like transcription factor DUF2731 PF10806.3 CCD23845.1 - 3.6e-33 114.4 1.5 3.6e-33 114.4 1.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2731) DUF1959 PF09218.5 CCD23845.1 - 0.02 14.6 0.7 1.5 8.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1959) G_glu_transpept PF01019.16 CCD23845.1 - 0.13 10.7 0.4 0.19 10.2 0.3 1.3 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase Pkinase PF00069.20 CCD23846.1 - 2.6e-47 161.1 0.1 1.3e-46 158.8 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23846.1 - 1.2e-21 76.9 0.0 1.1e-20 73.7 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD23846.1 - 0.00012 21.1 0.0 0.0016 17.4 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Sas10_Utp3 PF04000.10 CCD23847.1 - 0.001 19.1 4.3 0.001 19.1 3.0 2.8 3 1 0 3 3 3 1 Sas10/Utp3/C1D family C2-set PF05790.10 CCD23847.1 - 0.091 12.7 0.7 0.091 12.7 0.5 2.5 1 1 1 2 2 2 0 Immunoglobulin C2-set domain GAGA_bind PF06217.7 CCD23847.1 - 0.29 11.0 13.6 0.35 10.8 9.4 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SRP-alpha_N PF04086.8 CCD23847.1 - 2.5 7.4 23.1 3.1 7.1 16.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GRAM PF02893.15 CCD23848.1 - 4.1e-17 61.4 0.7 2.7e-16 58.8 0.2 2.4 2 0 0 2 2 2 1 GRAM domain Pkinase PF00069.20 CCD23849.1 - 1.7e-43 148.6 0.0 4.2e-43 147.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 CCD23849.1 - 7.1e-42 142.2 1.3 7.1e-42 142.2 0.9 2.0 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 CCD23849.1 - 9.2e-21 74.0 0.0 3.4e-18 65.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase PQQ PF01011.16 CCD23849.1 - 6.7e-05 22.2 0.4 0.86 9.2 0.0 3.5 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_2 PF13360.1 CCD23849.1 - 0.0043 16.5 0.0 0.011 15.1 0.0 1.7 1 0 0 1 1 1 1 PQQ-like domain Kdo PF06293.9 CCD23849.1 - 0.007 15.4 0.1 0.014 14.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PepSY PF03413.14 CCD23849.1 - 0.097 13.3 0.1 0.31 11.6 0.1 1.9 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain ABA_GPCR PF12430.3 CCD23850.1 - 7.2e-58 194.9 6.2 7.2e-58 194.9 4.3 2.5 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CCD23850.1 - 2.6e-14 52.9 0.1 6.5e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) MIF4G PF02854.14 CCD23851.1 - 3.3e-47 160.6 41.5 2e-21 76.3 5.9 3.8 4 0 0 4 4 4 3 MIF4G domain Upf2 PF04050.9 CCD23851.1 - 1.3e-15 57.5 19.9 1.3e-15 57.5 13.8 2.7 1 1 0 2 2 2 1 Up-frameshift suppressor 2 CENP-T PF15511.1 CCD23851.1 - 0.034 13.4 20.6 0.059 12.6 14.3 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF4162 PF13732.1 CCD23851.1 - 0.17 12.4 0.1 0.17 12.4 0.1 4.8 5 1 1 6 6 6 0 Domain of unknown function (DUF4162) SpoIIE PF07228.7 CCD23852.1 - 3.2e-30 105.2 0.0 4.1e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CCD23852.1 - 9.4e-10 38.3 0.7 2.4e-05 23.8 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CCD23852.1 - 2.4e-06 27.1 0.2 5.6e-06 25.8 0.2 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Reovirus_M2 PF05993.7 CCD23852.1 - 0.0064 14.3 0.0 0.0078 14.0 0.0 1.2 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) PPC PF04151.10 CCD23852.1 - 0.077 13.9 1.4 0.077 13.9 1.0 2.3 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Trp_repressor PF01371.14 CCD23853.1 - 0.048 13.5 0.5 0.34 10.8 0.1 2.5 2 0 0 2 2 2 0 Trp repressor protein SMP_2 PF10144.4 CCD23853.1 - 0.068 12.2 0.1 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin Abhydrolase_6 PF12697.2 CCD23854.1 - 1.4e-17 64.4 0.0 1.9e-17 63.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD23854.1 - 1.7e-12 47.3 0.0 2.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCD23854.1 - 6.3e-08 32.4 0.0 1.2e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCD23854.1 - 0.00036 20.3 0.0 0.00084 19.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 CCD23854.1 - 0.00045 19.8 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CCD23854.1 - 0.014 14.9 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 CCD23854.1 - 0.028 13.6 0.1 0.059 12.6 0.1 1.5 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.3 CCD23854.1 - 0.041 13.2 0.0 0.16 11.3 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) CN_hydrolase PF00795.17 CCD23855.1 - 1.5e-26 92.9 0.0 2.4e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 CCD23855.1 - 9e-22 77.1 0.0 2.9e-21 75.4 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 CCD23855.1 - 0.0088 15.5 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Oxysterol_BP PF01237.13 CCD23856.1 - 5.6e-104 347.4 1.0 1.3e-103 346.2 0.7 1.6 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 CCD23856.1 - 1.6e-33 114.5 0.6 1.6e-33 114.5 0.4 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 CCD23856.1 - 0.099 12.9 11.4 1.6 8.9 3.9 3.8 2 1 0 2 2 2 0 Pleckstrin homology domain Prenyltrans PF00432.16 CCD23857.1 - 5.5e-25 86.6 0.1 2.3e-08 33.4 0.0 4.2 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 CCD23857.1 - 5.8e-24 84.1 0.0 1.3e-11 44.4 0.1 5.4 3 2 2 5 5 5 5 Prenyltransferase-like Prenyltrans_2 PF13249.1 CCD23857.1 - 3.8e-21 75.5 0.0 9.4e-10 38.8 0.0 5.3 2 1 3 5 5 5 5 Prenyltransferase-like Cyclin PF08613.6 CCD23858.1 - 7.3e-11 42.6 1.7 9.7e-11 42.2 1.1 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCD23858.1 - 0.00029 20.4 1.4 0.00063 19.3 0.7 1.9 1 1 0 1 1 1 1 Cyclin, N-terminal domain DUF2806 PF10987.3 CCD23858.1 - 0.022 14.2 3.6 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2806) Met_10 PF02475.11 CCD23859.1 - 7.6e-75 250.8 0.2 1.4e-74 250.0 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MethyltransfD12 PF02086.10 CCD23859.1 - 0.0046 16.4 0.0 0.0081 15.6 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase DUF4221 PF13970.1 CCD23859.1 - 0.0055 16.0 0.2 0.0091 15.3 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4221) DUF1140 PF06600.6 CCD23859.1 - 0.011 15.8 0.1 0.027 14.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1140) TRM PF02005.11 CCD23859.1 - 0.024 13.6 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_18 PF12847.2 CCD23859.1 - 0.071 13.6 0.0 0.17 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ECR1_N PF14382.1 CCD23860.1 - 1.7e-12 46.4 0.0 3.9e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 CCD23860.1 - 0.017 15.0 0.3 0.52 10.2 0.0 3.0 3 1 0 3 3 3 0 Exosome component EXOSC1/CSL4 DS PF01916.12 CCD23861.1 - 3.9e-148 492.4 0.0 4.7e-148 492.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase GYF PF02213.11 CCD23862.1 - 0.025 14.1 0.0 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 GYF domain MaoC_dehydratas PF01575.14 CCD23862.1 - 0.092 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 MaoC like domain TFIIH_BTF_p62_N PF08567.6 CCD23863.1 - 4.3e-23 80.7 0.1 1.1e-22 79.4 0.1 1.8 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 CCD23863.1 - 6.4e-23 80.2 8.0 9.6e-13 47.6 0.6 2.9 3 0 0 3 3 3 2 BSD domain SPC25 PF06703.6 CCD23863.1 - 0.032 13.8 2.1 1.1 8.7 0.1 3.5 4 0 0 4 4 4 0 Microsomal signal peptidase 25 kDa subunit (SPC25) RNase_PH PF01138.16 CCD23864.1 - 2.3e-18 66.7 0.0 4e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCD23864.1 - 8.4e-12 44.8 0.1 1.6e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_P_p30 PF01876.11 CCD23865.1 - 4.4e-49 165.5 0.4 6.2e-49 165.0 0.3 1.2 1 0 0 1 1 1 1 RNase P subunit p30 ApbA PF02558.11 CCD23867.1 - 2.1e-29 101.9 0.0 3.3e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 CCD23867.1 - 5.1e-29 100.8 0.1 8.2e-29 100.1 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 CCD23867.1 - 0.069 12.8 0.0 0.23 11.1 0.0 1.9 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HSP70 PF00012.15 CCD23868.1 - 1.9e-75 254.0 0.6 1.9e-75 254.0 0.4 2.2 1 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CCD23868.1 - 2.3e-09 36.3 0.0 3.5e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein HAD_2 PF13419.1 CCD23869.1 - 5e-17 62.6 0.0 7.1e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCD23869.1 - 1.3e-06 28.0 0.1 2.3e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCD23869.1 - 6.4e-06 26.7 0.0 2e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCD23869.1 - 0.00027 21.1 0.0 0.00035 20.7 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCD23870.1 - 1.7e-13 51.1 0.0 2.2e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCD23870.1 - 1.2e-05 24.8 0.1 2.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCD23870.1 - 0.00036 21.0 0.0 0.0055 17.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCD23870.1 - 0.013 15.6 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FAD_binding_1 PF00667.15 CCD23871.1 - 3.4e-62 209.7 0.0 7.4e-62 208.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 CCD23871.1 - 5.8e-27 94.4 0.6 1.1e-26 93.5 0.4 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCD23871.1 - 1.4e-21 77.0 0.1 5.3e-21 75.2 0.0 2.0 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain Spore_IV_A PF09547.5 CCD23871.1 - 0.0055 15.4 0.0 0.011 14.4 0.0 1.4 1 0 0 1 1 1 1 Stage IV sporulation protein A (spore_IV_A) PSII_Pbs27 PF13326.1 CCD23871.1 - 0.078 12.9 0.0 0.21 11.5 0.0 1.7 1 0 0 1 1 1 0 Photosystem II Pbs27 Med20 PF08612.6 CCD23872.1 - 7.7e-33 113.5 0.4 8.9e-33 113.3 0.3 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex V-ATPase_G PF03179.10 CCD23873.1 - 6.2e-30 103.5 10.7 7.3e-30 103.3 7.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit GA PF01468.12 CCD23873.1 - 0.031 14.4 8.5 0.037 14.1 4.8 2.1 1 1 1 2 2 2 0 GA module AHH PF14412.1 CCD23873.1 - 0.035 14.0 0.4 0.042 13.8 0.3 1.2 1 0 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH S_layer_C PF05124.7 CCD23873.1 - 0.044 13.4 5.1 0.049 13.2 3.5 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region DUF1071 PF06378.6 CCD23873.1 - 0.053 12.6 0.5 0.061 12.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) ATP-synt_B PF00430.13 CCD23873.1 - 0.06 13.1 14.7 0.34 10.7 10.2 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Phage_min_cap2 PF06152.6 CCD23873.1 - 0.12 11.3 4.1 0.14 11.1 2.9 1.1 1 0 0 1 1 1 0 Phage minor capsid protein 2 Potyvirid-P3 PF13608.1 CCD23873.1 - 0.14 11.2 4.8 0.16 11.1 3.3 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Minor_capsid_1 PF10665.4 CCD23873.1 - 0.21 11.4 1.1 0.29 10.9 0.8 1.2 1 0 0 1 1 1 0 Minor capsid protein GTP_cyclohydro2 PF00925.15 CCD23873.1 - 0.3 10.3 2.3 2.2 7.4 0.3 2.4 1 1 2 3 3 3 0 GTP cyclohydrolase II YlqD PF11068.3 CCD23873.1 - 0.48 10.4 8.0 0.75 9.8 5.1 1.6 1 1 0 1 1 1 0 YlqD protein DUF3552 PF12072.3 CCD23873.1 - 0.53 9.4 15.0 5.5 6.1 10.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) Ribosomal_L11 PF00298.14 CCD23873.1 - 1.6 8.9 4.1 8.3 6.6 2.9 2.0 1 1 0 1 1 1 0 Ribosomal protein L11, RNA binding domain Aldedh PF00171.17 CCD23874.1 - 1.8e-109 366.1 0.0 2.5e-109 365.7 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RRF PF01765.14 CCD23875.1 - 1.2e-32 112.7 5.1 1.6e-32 112.2 3.5 1.2 1 0 0 1 1 1 1 Ribosome recycling factor FA_hydroxylase PF04116.8 CCD23876.1 - 3.8e-17 62.7 5.6 3.8e-17 62.7 3.9 2.3 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Sec23_trunk PF04811.10 CCD23877.1 - 3.3e-11 43.0 4.2 8.2e-11 41.7 2.9 1.6 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 CCD23877.1 - 6.3e-06 25.6 2.2 2.5e-05 23.7 1.5 2.1 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 CCD23877.1 - 0.00076 18.8 0.5 0.0039 16.6 0.1 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Tmemb_55A PF09788.4 CCD23877.1 - 0.013 14.6 0.1 0.022 13.9 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 55A Zn-ribbon_8 PF09723.5 CCD23877.1 - 0.019 14.9 0.8 0.045 13.7 0.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain zf-H2C2_2 PF13465.1 CCD23877.1 - 0.14 12.4 1.7 4.4 7.7 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger double domain Brr6_like_C_C PF10104.4 CCD23878.1 - 2.4e-41 140.4 4.9 4.1e-41 139.6 3.4 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain Aldedh PF00171.17 CCD23879.1 - 1.8e-97 326.6 0.0 2.1e-97 326.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PIH1 PF08190.7 CCD23880.1 - 9.6e-20 71.2 8.0 1.6e-19 70.5 1.0 2.9 3 0 0 3 3 3 2 pre-RNA processing PIH1/Nop17 AA_kinase PF00696.23 CCD23881.1 - 1e-29 103.7 1.4 1.9e-27 96.4 0.1 2.3 2 0 0 2 2 2 2 Amino acid kinase family PUA PF01472.15 CCD23881.1 - 7.3e-12 44.8 0.0 1.6e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 PUA domain PGM_PMM_I PF02878.11 CCD23882.1 - 2.4e-19 69.1 0.2 3.9e-19 68.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CCD23882.1 - 1.1e-12 48.1 0.0 1.9e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CCD23882.1 - 2.6e-10 40.3 0.0 5.7e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF3414 PF11894.3 CCD23883.1 - 0 1327.5 75.0 0 1326.4 52.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3414) Nsp1_C PF05064.8 CCD23884.1 - 2.2e-38 130.4 6.9 2.2e-38 130.4 4.7 2.1 1 1 1 2 2 2 1 Nsp1-like C-terminal region Muted PF14942.1 CCD23884.1 - 2.1 8.2 7.2 0.42 10.4 1.4 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein RabGAP-TBC PF00566.13 CCD23885.1 - 1.8e-14 53.7 8.4 1.8e-14 53.7 5.8 2.4 1 1 1 2 2 2 1 Rab-GTPase-TBC domain LRR_6 PF13516.1 CCD23886.1 - 0.025 14.6 9.9 25 5.3 0.2 5.7 6 0 0 6 6 6 0 Leucine Rich repeat LRR_4 PF12799.2 CCD23886.1 - 2.8 7.6 14.3 0.23 11.1 0.9 4.0 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCD23886.1 - 7.3 7.0 10.2 24 5.4 0.1 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat Dynamin_M PF01031.15 CCD23887.1 - 2.3e-107 358.1 0.1 5.8e-107 356.8 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 CCD23887.1 - 1e-54 184.8 2.4 2.5e-54 183.6 0.1 2.7 2 1 0 2 2 2 1 Dynamin family GED PF02212.13 CCD23887.1 - 5e-29 100.0 4.4 1.6e-28 98.4 3.0 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCD23887.1 - 0.00012 21.9 0.5 0.0039 17.1 0.3 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCD23887.1 - 0.0095 16.4 0.0 0.03 14.8 0.0 1.9 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 CCD23887.1 - 0.088 12.5 0.1 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Fasciclin PF02469.17 CCD23888.1 - 1.1e-17 64.1 8.6 1.7e-06 28.0 0.2 6.3 5 2 0 5 5 5 5 Fasciclin domain PX PF00787.19 CCD23889.1 - 3.6e-24 84.7 0.3 3.6e-24 84.7 0.2 2.3 3 0 0 3 3 3 1 PX domain Vps5 PF09325.5 CCD23889.1 - 7.1e-07 28.7 21.4 0.0002 20.6 2.1 2.5 3 0 0 3 3 3 2 Vps5 C terminal like DUF4239 PF14023.1 CCD23889.1 - 0.14 11.5 2.5 0.33 10.3 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) DUF4618 PF15397.1 CCD23889.1 - 0.15 11.3 20.2 0.52 9.5 13.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) NPV_P10 PF05531.7 CCD23889.1 - 0.16 12.2 8.5 1.8 8.8 2.9 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Nup54 PF13874.1 CCD23889.1 - 0.59 9.8 4.4 0.28 10.8 0.6 2.2 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 PilJ PF13675.1 CCD23889.1 - 0.79 10.0 3.2 3.3 8.0 0.1 3.2 2 1 2 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Baculo_PEP_C PF04513.7 CCD23889.1 - 0.87 9.4 7.7 0.55 10.0 1.1 2.7 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 CCD23889.1 - 1.3 8.1 6.5 1.4 7.9 2.0 2.4 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Rootletin PF15035.1 CCD23889.1 - 1.9 8.4 13.8 0.66 9.9 2.9 2.3 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF4164 PF13747.1 CCD23889.1 - 3.7 7.7 8.4 5.3 7.2 0.2 3.8 2 2 2 4 4 4 0 Domain of unknown function (DUF4164) dCMP_cyt_deam_1 PF00383.17 CCD23890.1 - 1.6e-20 72.6 0.2 2.7e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CCD23890.1 - 0.044 13.6 0.9 0.2 11.4 0.6 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase HSP70 PF00012.15 CCD23891.1 - 6.8e-266 882.9 12.3 7.8e-266 882.7 8.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCD23891.1 - 2.5e-19 69.0 1.7 6.1e-18 64.5 0.2 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 CCD23891.1 - 0.0015 17.6 3.8 0.048 12.7 0.0 3.3 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 CCD23891.1 - 0.0097 15.2 0.1 0.17 11.1 0.1 2.4 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.11 CCD23891.1 - 0.054 13.1 0.0 0.21 11.2 0.0 2.0 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Evr1_Alr PF04777.8 CCD23891.1 - 0.16 11.9 0.1 0.33 10.8 0.0 1.4 1 0 0 1 1 1 0 Erv1 / Alr family FtsA PF14450.1 CCD23891.1 - 1.9 8.3 11.3 0.23 11.3 0.6 3.4 3 2 0 3 3 3 0 Cell division protein FtsA DEAD PF00270.24 CCD23892.1 - 1.9e-45 154.3 0.8 8.6e-45 152.2 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CCD23892.1 - 2.1e-24 84.8 0.2 4.5e-24 83.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CCD23892.1 - 2.3e-22 78.6 0.0 5.2e-22 77.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CCD23892.1 - 6.8e-05 22.8 0.0 0.00017 21.6 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain HORMA PF02301.13 CCD23893.1 - 1.4e-43 148.7 0.1 1.7e-43 148.5 0.1 1.0 1 0 0 1 1 1 1 HORMA domain DUF1682 PF07946.9 CCD23893.1 - 0.034 12.9 0.1 0.045 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) ATG13 PF10033.4 CCD23893.1 - 0.057 12.8 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 13 RRM_1 PF00076.17 CCD23894.1 - 1.5e-15 56.5 0.1 4e-09 35.9 0.0 3.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD23894.1 - 4.2e-11 42.6 0.0 3.4e-08 33.3 0.0 3.0 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD23894.1 - 8.6e-08 31.9 0.0 0.013 15.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.19 CCD23895.1 - 2.4e-12 46.7 0.0 3.6e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 CCD23895.1 - 9.1e-05 22.4 0.1 0.00011 22.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCD23895.1 - 0.00011 22.3 0.0 0.00013 22.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCD23895.1 - 0.0014 18.4 0.1 0.0028 17.5 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCD23895.1 - 0.0026 17.8 0.0 0.0041 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCD23895.1 - 0.015 15.1 0.0 0.035 14.0 0.0 1.5 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 CCD23895.1 - 0.031 13.8 0.1 0.21 11.1 0.0 2.2 1 1 2 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCD23895.1 - 0.065 13.3 0.0 0.088 12.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCD23895.1 - 0.093 12.4 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein CBF PF03914.12 CCD23896.1 - 8.1e-35 119.6 0.3 3.2e-34 117.7 0.2 2.1 1 0 0 1 1 1 1 CBF/Mak21 family NOC3p PF07540.6 CCD23896.1 - 2e-34 117.7 0.4 2e-34 117.7 0.3 2.7 3 0 0 3 3 3 1 Nucleolar complex-associated protein DUF3504 PF12012.3 CCD23896.1 - 0.73 9.5 6.9 0.42 10.3 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3504) Candida_ALS_N PF11766.3 CCD23897.1 - 1.1e-67 227.5 4.3 1.1e-67 227.5 3.0 1.6 2 0 0 2 2 2 1 Cell-wall agglutinin N-terminal ligand-sugar binding CMS1 PF14617.1 CCD23898.1 - 7.9e-19 67.7 11.1 3.9e-18 65.4 7.7 2.0 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Mt_ATP-synt_B PF05405.9 CCD23898.1 - 0.073 12.5 6.2 0.065 12.6 0.7 2.4 2 0 0 2 2 2 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) VitD-bind_III PF09164.5 CCD23898.1 - 0.4 10.3 0.0 0.4 10.3 0.0 2.3 3 0 0 3 3 3 0 Vitamin D binding protein, domain III SMC_Nse1 PF07574.8 CCD23899.1 - 2.6e-46 157.7 0.3 3.1e-46 157.5 0.2 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 CCD23899.1 - 1.7e-10 40.6 8.8 3.3e-10 39.7 6.1 1.5 1 0 0 1 1 1 1 RING-like domain Ribosomal_L24e PF01246.15 CCD23900.1 - 1.9e-29 101.3 1.9 4.6e-29 100.0 1.3 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 CCD23900.1 - 0.42 10.2 4.1 0.88 9.2 2.8 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Proteasome PF00227.21 CCD23902.1 - 1.4e-45 154.9 1.2 1.6e-45 154.7 0.8 1.0 1 0 0 1 1 1 1 Proteasome subunit Sfi1 PF08457.5 CCD23903.1 - 1.7e-30 105.9 82.4 2.3e-29 102.2 42.7 2.1 1 1 1 2 2 2 2 Sfi1 spindle body protein Sfi1_C PF10638.4 CCD23903.1 - 2.4e-17 63.2 2.6 2.4e-17 63.2 1.8 3.3 3 1 0 3 3 3 1 Spindle body associated protein C-terminus Ribophorin_I PF04597.9 CCD23904.1 - 3.1e-121 404.9 4.9 3.5e-121 404.7 3.4 1.0 1 0 0 1 1 1 1 Ribophorin I DUF221 PF02714.10 CCD23906.1 - 6.6e-86 288.1 22.9 6.6e-86 288.1 15.9 2.2 4 0 0 4 4 4 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCD23906.1 - 5.7e-28 97.4 0.4 5.7e-28 97.4 0.3 2.9 3 1 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF2404 PF10296.4 CCD23907.1 - 0.0025 17.9 0.2 0.0075 16.3 0.0 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DEAD PF00270.24 CCD23909.1 - 5.5e-46 156.1 0.2 5.5e-46 156.1 0.1 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD23909.1 - 7e-27 93.1 0.1 3e-26 91.0 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain COX17 PF05051.8 CCD23910.1 - 3.6e-20 71.7 6.4 4.4e-20 71.4 4.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 CCD23910.1 - 0.00026 20.6 4.8 0.011 15.5 0.1 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CCD23910.1 - 0.0048 16.7 3.5 0.0076 16.1 2.5 1.4 1 0 0 1 1 1 1 CHCH domain PPI_Ypi1 PF07491.6 CCD23910.1 - 0.24 11.0 3.2 0.32 10.6 2.2 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor DPPIV_N PF00930.16 CCD23911.1 - 8.7e-102 340.3 3.2 1.2e-101 339.7 2.2 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CCD23911.1 - 2.2e-49 167.5 1.1 3.3e-49 166.9 0.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCD23911.1 - 4e-09 36.3 0.0 1.1e-08 35.0 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCD23911.1 - 1.9e-05 24.6 0.0 0.00017 21.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CCD23911.1 - 0.035 13.6 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CCD23911.1 - 0.064 12.6 0.4 0.24 10.8 0.2 1.9 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Thiolase_N PF00108.18 CCD23912.1 - 1.5e-86 289.6 0.0 2e-86 289.2 0.0 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCD23912.1 - 3e-48 162.2 0.5 5.8e-48 161.3 0.3 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCD23912.1 - 0.0054 16.2 0.1 0.021 14.2 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ThiF PF00899.16 CCD23913.1 - 4.5e-53 178.7 0.0 1.7e-31 108.8 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 CCD23913.1 - 2.4e-44 150.4 0.0 8.2e-44 148.7 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 CCD23913.1 - 1.8e-35 120.3 3.9 1.1e-22 79.3 0.1 2.8 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCD23913.1 - 1.6e-27 94.5 0.1 1e-20 72.7 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Gly_transf_sug PF04488.10 CCD23914.1 - 7.9e-10 39.0 0.1 2.6e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif BBP1_C PF15272.1 CCD23914.1 - 0.0037 16.8 1.8 0.007 15.9 1.2 1.4 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal IncA PF04156.9 CCD23914.1 - 0.11 12.0 0.9 0.18 11.3 0.6 1.2 1 0 0 1 1 1 0 IncA protein Septin PF00735.13 CCD23916.1 - 9.9e-105 349.5 0.2 2.5e-104 348.2 0.0 1.7 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CCD23916.1 - 7.5e-08 32.3 0.0 1.7e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCD23916.1 - 4.2e-05 22.7 0.7 0.00027 20.1 0.5 2.1 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CCD23916.1 - 0.00014 21.0 0.0 0.00014 21.0 0.0 2.3 2 0 0 2 2 1 1 AIG1 family ABC_tran PF00005.22 CCD23916.1 - 0.00025 21.3 0.7 0.0014 18.9 0.0 2.1 2 0 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 CCD23916.1 - 0.00051 19.8 7.6 0.0027 17.5 0.1 3.0 2 2 1 3 3 3 2 Dynamin family IIGP PF05049.8 CCD23916.1 - 0.0018 17.1 0.1 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Miro PF08477.8 CCD23916.1 - 0.0035 17.8 0.0 0.0096 16.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 CCD23916.1 - 0.011 14.9 0.4 0.079 12.2 0.3 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 CCD23916.1 - 0.039 13.4 0.4 1.4 8.4 0.3 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 CCD23916.1 - 0.054 14.3 3.2 0.32 11.8 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CCD23916.1 - 0.074 12.4 3.2 0.13 11.6 2.2 1.8 1 1 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 CCD23916.1 - 0.43 10.8 12.7 0.2 11.9 5.8 2.3 2 0 0 2 2 2 0 AAA domain IGPS PF00218.16 CCD23917.1 - 6e-92 307.2 1.1 9.1e-92 306.6 0.8 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 CCD23917.1 - 2.9e-52 176.9 0.1 5.2e-52 176.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCD23917.1 - 6.8e-10 38.7 0.1 1.5e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 CCD23917.1 - 0.0097 15.4 0.3 0.024 14.1 0.2 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain DUF1040 PF06288.8 CCD23917.1 - 0.015 15.5 0.4 0.095 12.9 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1040) His_biosynth PF00977.16 CCD23917.1 - 0.086 12.0 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein Syja_N PF02383.13 CCD23918.1 - 1.2e-84 283.8 5.0 1.6e-84 283.4 3.5 1.2 1 0 0 1 1 1 1 SacI homology domain Ribosomal_L30 PF00327.15 CCD23919.1 - 8.7e-15 54.0 0.6 2.3e-14 52.6 0.4 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e DUF3876 PF12992.2 CCD23919.1 - 0.57 10.1 2.5 12 5.9 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) ANAPC15 PF15243.1 CCD23919.1 - 2.9 8.0 9.4 20 5.3 0.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 WD40 PF00400.27 CCD23920.1 - 4e-49 162.8 11.7 1.2e-11 44.0 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 CCD23920.1 - 3e-09 35.5 9.4 0.011 13.9 0.1 5.0 3 1 2 5 5 5 5 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCD23920.1 - 1.9e-06 26.8 1.7 0.15 10.7 0.1 3.4 1 1 2 3 3 3 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 CCD23920.1 - 0.00034 19.0 0.0 0.048 11.9 0.0 2.1 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.1 CCD23920.1 - 0.00082 18.5 0.4 0.55 9.2 0.1 2.8 2 1 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 CCD23920.1 - 0.014 14.2 0.0 0.034 12.9 0.0 1.6 1 1 0 2 2 2 0 Coatomer WD associated region DUF3312 PF11768.3 CCD23920.1 - 0.019 13.1 0.0 0.038 12.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) DnaJ PF00226.26 CCD23921.1 - 5.5e-25 86.8 0.6 8.6e-25 86.2 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCD23921.1 - 1e-24 86.2 0.5 2.9e-21 75.1 0.0 2.8 2 1 0 2 2 2 2 DnaJ C terminal domain Malate_DH PF12434.3 CCD23921.1 - 0.056 13.1 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Malate dehydrogenase enzyme Fork_head_N PF08430.7 CCD23921.1 - 0.29 11.5 8.8 0.57 10.5 6.1 1.4 1 0 0 1 1 1 0 Forkhead N-terminal region Pirin PF02678.11 CCD23922.1 - 9.6e-28 96.1 0.4 1.6e-27 95.5 0.3 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 CCD23922.1 - 8.4e-15 54.7 0.0 4.7e-14 52.3 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 CCD23922.1 - 0.0021 17.5 0.4 0.0021 17.5 0.3 1.7 2 0 0 2 2 2 1 Cupin domain Alg6_Alg8 PF03155.10 CCD23923.1 - 1.2e-159 532.1 31.1 1.5e-159 531.8 21.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Cyclin PF08613.6 CCD23924.1 - 8.9e-28 97.5 1.1 8.9e-28 97.5 0.8 2.0 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 CCD23924.1 - 0.00018 21.0 0.0 0.00034 20.1 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-DHHC PF01529.15 CCD23925.1 - 2e-34 118.4 14.9 2e-34 118.4 10.3 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 CCD23925.1 - 0.05 13.3 0.3 0.083 12.6 0.2 1.3 1 0 0 1 1 1 0 Transglutaminase-like superfamily PAH PF02671.16 CCD23926.1 - 9.6e-45 149.9 5.8 1.3e-16 59.9 0.7 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CCD23926.1 - 3.1e-43 145.6 0.3 3.1e-43 145.6 0.2 2.9 2 0 0 2 2 2 1 Sin3 family co-repressor RNA_pol_L_2 PF13656.1 CCD23927.1 - 2.7e-24 84.4 0.0 3.4e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CCD23927.1 - 2.2e-10 39.4 0.0 3e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Sep15_SelM PF08806.6 CCD23927.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Sep15/SelM redox domain Pkinase PF00069.20 CCD23928.1 - 7.8e-72 241.5 0.0 7.8e-72 241.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD23928.1 - 8.8e-40 136.4 0.0 1.5e-39 135.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CCD23928.1 - 2.1e-33 114.0 0.0 1.7e-17 63.1 0.0 2.7 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 CCD23928.1 - 1.5e-09 37.2 0.0 2.1e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like SH3_3 PF08239.6 CCD23928.1 - 0.0015 18.6 0.1 0.0031 17.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Kdo PF06293.9 CCD23928.1 - 0.018 14.0 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD23928.1 - 0.17 11.5 0.0 0.3 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Topoisom_I_N PF02919.10 CCD23929.1 - 6.1e-99 329.6 0.3 6.1e-99 329.6 0.2 3.9 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CCD23929.1 - 1.5e-84 282.7 2.0 1.5e-84 282.7 1.4 2.7 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 CCD23929.1 - 1.9e-32 110.7 0.6 7.2e-32 108.8 0.4 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain Transformer PF06495.6 CCD23930.1 - 0.019 14.8 4.0 0.12 12.2 3.1 2.0 2 0 0 2 2 2 0 Fruit fly transformer protein Senescence_reg PF04520.8 CCD23930.1 - 0.95 9.9 11.3 1.2 9.6 3.4 2.4 2 0 0 2 2 2 0 Senescence regulator DUF2217 PF10265.4 CCD23930.1 - 6.5 5.3 20.7 1.1 7.9 1.5 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2217) Polyketide_cyc PF03364.15 CCD23931.1 - 1e-17 64.3 0.0 1.4e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 CCD23931.1 - 0.00069 19.7 0.0 0.00098 19.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SAC3 PF12209.3 CCD23931.1 - 0.2 11.8 1.3 0.58 10.3 0.1 2.3 3 0 0 3 3 3 0 Leucine permease transcriptional regulator helical domain DUF2404 PF10296.4 CCD23932.1 - 2.2e-05 24.5 0.1 0.00013 22.0 0.1 2.1 1 1 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PX PF00787.19 CCD23933.1 - 1.4e-19 69.9 1.0 2.9e-19 68.9 0.1 2.0 2 0 0 2 2 2 1 PX domain RTC PF01137.16 CCD23934.1 - 2.5e-61 206.3 0.0 3e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CCD23934.1 - 2.9e-32 110.7 0.0 4.8e-32 110.0 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PLA2_B PF01735.13 CCD23935.1 - 4.3e-211 701.3 13.0 1.7e-210 699.3 9.0 2.0 1 1 0 1 1 1 1 Lysophospholipase catalytic domain DUF3051 PF11252.3 CCD23935.1 - 0.018 14.5 0.7 0.062 12.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3051) Nucleoplasmin PF03066.10 CCD23935.1 - 1.1 8.8 3.7 1.9 7.9 1.2 2.0 2 0 0 2 2 2 0 Nucleoplasmin Histone PF00125.19 CCD23936.1 - 5.1e-23 80.9 0.0 6.6e-23 80.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCD23936.1 - 0.00044 20.2 0.0 0.00062 19.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-RING_2 PF13639.1 CCD23937.1 - 2.4e-10 40.0 9.1 1e-08 34.8 6.3 2.3 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCD23937.1 - 3.5e-08 33.4 3.0 1.2e-07 31.7 2.1 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CCD23937.1 - 4e-07 29.5 2.4 2.2e-06 27.2 0.6 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD23937.1 - 2.8e-06 27.2 3.9 2.8e-06 27.2 2.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCD23937.1 - 1.6e-05 24.5 6.0 5.5e-05 22.8 4.3 1.8 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCD23937.1 - 7.7e-05 22.2 7.2 0.00035 20.1 5.0 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCD23937.1 - 0.002 17.8 2.0 0.002 17.8 1.4 2.7 2 1 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 CCD23937.1 - 0.035 13.6 0.4 0.08 12.4 0.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 CCD23937.1 - 0.067 13.0 5.5 0.046 13.5 1.5 2.4 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CCD23937.1 - 0.14 12.0 3.3 0.078 12.8 0.7 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CCD23937.1 - 1.6 8.7 4.9 19 5.3 1.9 2.8 1 1 2 3 3 3 0 FANCL C-terminal domain RINGv PF12906.2 CCD23937.1 - 5.5 7.1 7.9 0.27 11.2 1.3 1.9 2 0 0 2 2 2 0 RING-variant domain Ribonuc_red_sm PF00268.16 CCD23938.1 - 4.3e-120 399.9 2.7 6.4e-120 399.3 1.9 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain PTPlike_phytase PF14566.1 CCD23938.1 - 0.057 13.4 0.7 0.76 9.8 0.4 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate HSP20 PF00011.16 CCD23939.1 - 8e-18 64.1 0.9 1e-17 63.8 0.7 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DNA_pol_E_B PF04042.11 CCD23940.1 - 1e-46 158.8 0.0 1.6e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B SAA PF00277.13 CCD23941.1 - 0.088 13.1 2.2 0.098 13.0 1.5 1.1 1 0 0 1 1 1 0 Serum amyloid A protein NYAP_C PF15452.1 CCD23941.1 - 1.2 8.0 4.9 1.2 8.1 3.4 1.0 1 0 0 1 1 1 0 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter Ribosomal_L35p PF01632.14 CCD23941.1 - 7.3 6.5 7.9 11 5.9 1.4 2.1 1 1 1 2 2 2 0 Ribosomal protein L35 SH3_1 PF00018.23 CCD23943.1 - 4e-09 35.7 0.3 1e-08 34.4 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCD23943.1 - 1.2e-08 34.2 0.0 2.8e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 CCD23943.1 - 2.2e-08 33.5 0.3 7.4e-08 31.8 0.2 2.0 1 0 0 1 1 1 1 Variant SH3 domain Sad1_UNC PF07738.8 CCD23944.1 - 3e-06 27.0 1.6 0.018 14.8 0.1 3.0 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal Thi4 PF01946.12 CCD23946.1 - 8.8e-94 312.8 0.1 1e-93 312.6 0.1 1.0 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CCD23946.1 - 2.3e-09 36.6 0.4 5.3e-08 32.1 0.1 2.3 1 1 2 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCD23946.1 - 2.8e-06 27.2 0.0 9.2e-06 25.6 0.1 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCD23946.1 - 3.2e-06 27.1 0.0 0.00019 21.3 0.2 2.2 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCD23946.1 - 1.1e-05 24.4 0.9 0.00033 19.6 0.3 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 CCD23946.1 - 3.2e-05 23.7 0.1 0.00012 21.8 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CCD23946.1 - 9.7e-05 21.4 0.2 0.00014 20.9 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_oxidored PF12831.2 CCD23946.1 - 0.0016 17.5 0.1 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 CCD23946.1 - 0.0016 16.9 0.2 0.0028 16.2 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 CCD23946.1 - 0.0024 17.9 0.3 0.0046 17.0 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF_assoc_1 PF08355.7 CCD23946.1 - 0.015 14.5 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 EF hand associated GIDA PF01134.17 CCD23946.1 - 0.019 13.8 0.4 0.049 12.4 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A K_oxygenase PF13434.1 CCD23946.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.9 CCD23946.1 - 0.13 10.8 0.1 0.19 10.3 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase ILVD_EDD PF00920.16 CCD23947.1 - 4.5e-203 675.4 0.3 5.1e-203 675.2 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family CTP_transf_2 PF01467.21 CCD23948.1 - 1.8e-24 86.5 0.0 3.8e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Cytidylyltransferase Innate_immun PF12782.2 CCD23948.1 - 0.6 9.2 12.2 1.2 8.3 8.5 1.4 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Rotamase PF00639.16 CCD23949.1 - 4.1e-29 101.1 0.1 6.2e-29 100.5 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CCD23949.1 - 1.6e-21 76.7 0.0 2.1e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CCD23949.1 - 6e-10 39.7 0.0 9.7e-10 39.1 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 CCD23949.1 - 3.8e-08 33.0 1.7 7.6e-08 32.0 1.1 1.5 1 0 0 1 1 1 1 WW domain THOC7 PF05615.8 CCD23949.1 - 0.0081 16.4 0.3 0.013 15.7 0.2 1.4 1 1 0 1 1 1 1 Tho complex subunit 7 Acyl_CoA_thio PF02551.10 CCD23950.1 - 4.9e-47 158.8 3.6 1.2e-34 118.7 0.9 3.1 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 CCD23950.1 - 2e-25 89.9 0.0 3.1e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily p12I PF12233.3 CCD23950.1 - 0.096 12.9 0.2 0.2 11.9 0.2 1.5 1 0 0 1 1 1 0 Human adult T cell leukemia/lymphoma virus protein DUF3533 PF12051.3 CCD23951.1 - 5.9e-126 420.2 26.9 7.7e-126 419.8 18.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) SUI1 PF01253.17 CCD23952.1 - 3.2e-21 74.9 2.4 5.5e-21 74.1 1.7 1.4 1 0 0 1 1 1 1 Translation initiation factor SUI1 PIN_2 PF10130.4 CCD23952.1 - 0.27 11.2 0.2 0.27 11.2 0.1 2.2 1 1 2 3 3 3 0 PIN domain RNase_PH PF01138.16 CCD23953.1 - 2e-26 92.8 0.0 2.9e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCD23953.1 - 3.3e-06 26.9 0.2 7.2e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Gp_dh_C PF02800.15 CCD23954.1 - 1e-73 245.9 0.0 1.6e-73 245.3 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CCD23954.1 - 1.3e-58 197.1 0.2 2.5e-58 196.3 0.0 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 CCD23954.1 - 0.12 11.4 0.1 0.25 10.4 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AA_permease PF00324.16 CCD23955.1 - 9e-134 446.3 32.5 1.2e-133 446.0 22.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD23955.1 - 1.3e-39 135.9 35.0 1.6e-39 135.6 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease PrgI PF12666.2 CCD23955.1 - 0.6 10.2 0.0 0.6 10.2 0.0 3.8 5 0 0 5 5 5 0 PrgI family protein EIF_2_alpha PF07541.7 CCD23956.1 - 2.8e-41 139.8 1.3 8.5e-41 138.2 0.2 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CCD23956.1 - 5.4e-14 52.0 1.0 1.6e-13 50.5 0.7 1.8 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 CCD23956.1 - 0.056 13.3 0.2 0.13 12.2 0.1 1.7 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Memo PF01875.12 CCD23957.1 - 9.6e-94 313.3 0.2 1.1e-93 313.1 0.1 1.0 1 0 0 1 1 1 1 Memo-like protein Mannosyl_trans PF05007.8 CCD23958.1 - 2.7e-85 286.1 28.0 3.6e-85 285.7 19.4 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 CCD23958.1 - 3.6e-11 42.5 28.8 2.9e-10 39.5 19.9 2.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 CCD23958.1 - 5.2e-09 35.9 1.1 5.2e-09 35.9 0.8 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) DUF4356 PF14266.1 CCD23960.1 - 0.0035 15.8 1.0 0.0042 15.5 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4356) SPC12 PF06645.8 CCD23961.1 - 7.8e-23 80.0 0.2 8.7e-23 79.9 0.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ATP-sulfurylase PF01747.12 CCD23962.1 - 1.1e-88 296.1 0.0 1.4e-88 295.7 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 CCD23962.1 - 1.8e-48 163.9 0.0 2.7e-48 163.3 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Glyco_hydro_16 PF00722.16 CCD23963.1 - 1e-44 152.0 2.2 1e-44 152.0 1.5 2.3 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 DUF1702 PF08012.6 CCD23963.1 - 0.085 11.4 0.1 0.15 10.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) DUF605 PF04652.11 CCD23963.1 - 4.5 6.5 24.2 6.1 6.1 16.8 1.1 1 0 0 1 1 1 0 Vta1 like RNA_pol_Rpb4 PF03874.11 CCD23964.1 - 7.8e-28 96.8 10.3 1.3e-27 96.0 7.1 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF764 PF05561.6 CCD23964.1 - 0.013 14.9 0.6 0.022 14.2 0.4 1.5 1 1 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF764) Rer1 PF03248.8 CCD23964.1 - 0.12 11.9 0.1 0.22 11.0 0.1 1.4 1 0 0 1 1 1 0 Rer1 family DUF1910 PF08928.5 CCD23964.1 - 0.78 9.7 6.1 2 8.4 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) VTC PF09359.5 CCD23965.1 - 2e-104 348.5 0.4 2.9e-104 348.0 0.0 1.4 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 CCD23965.1 - 8.5e-23 81.5 11.8 1.4e-10 41.4 3.6 3.4 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 CCD23965.1 - 4.1e-07 30.1 5.3 4.6e-07 29.9 2.6 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TEA PF01285.13 CCD23965.1 - 0.13 11.3 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 TEA/ATTS domain family Mad3_BUB1_I PF08311.7 CCD23966.1 - 6.4e-35 119.6 1.5 1.7e-34 118.3 1.0 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 CCD23966.1 - 3.2e-21 74.9 0.2 1.4e-20 72.9 0.1 2.2 1 1 0 1 1 1 1 Mad3/BUB1 homology region 2 Mer2 PF09074.5 CCD23967.1 - 5.1e-29 101.5 22.1 9.5e-29 100.6 15.3 1.4 1 0 0 1 1 1 1 Mer2 DUF4557 PF15101.1 CCD23967.1 - 0.46 10.2 5.3 0.75 9.6 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) KxDL PF10241.4 CCD23967.1 - 3 7.8 11.9 0.044 13.6 1.9 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein LSM PF01423.17 CCD23968.1 - 1.7e-09 37.1 0.3 1.7e-09 37.1 0.2 1.9 1 1 1 2 2 2 1 LSM domain Aldolase_II PF00596.16 CCD23969.1 - 5.3e-39 133.7 0.0 6.4e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain HEAT PF02985.17 CCD23970.1 - 0.00037 20.3 0.3 1.4 9.1 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.2 CCD23970.1 - 0.0088 16.4 0.0 6.8 7.1 0.0 2.7 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region Thrombin_light PF09396.5 CCD23970.1 - 0.023 14.3 0.1 0.079 12.5 0.1 1.9 1 0 0 1 1 1 0 Thrombin light chain HEAT_EZ PF13513.1 CCD23970.1 - 0.073 13.5 0.1 2 9.0 0.0 2.7 2 0 0 2 2 2 0 HEAT-like repeat TPP_enzyme_M PF00205.17 CCD23971.1 - 1.1e-35 122.3 0.0 4.9e-35 120.2 0.0 2.1 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 CCD23971.1 - 1.6e-34 118.8 0.0 2.6e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCD23971.1 - 9.4e-15 54.4 0.0 1.8e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 CCD23971.1 - 0.034 12.8 0.1 0.065 11.9 0.1 1.4 1 0 0 1 1 1 0 Dehydrogenase E1 component Gp_dh_C PF02800.15 CCD23972.1 - 1.9e-73 245.0 0.1 2.8e-73 244.5 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CCD23972.1 - 8.2e-59 197.9 0.1 1.5e-58 197.0 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 CCD23972.1 - 0.067 12.3 0.2 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.15 CCD23972.1 - 0.072 13.0 0.0 0.23 11.3 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ribosomal_S2 PF00318.15 CCD23973.1 - 8.5e-40 136.2 0.0 1.1e-20 73.7 0.0 2.6 2 1 1 3 3 3 2 Ribosomal protein S2 Ferric_reduct PF01794.14 CCD23974.1 - 9.1e-20 71.0 5.5 9.1e-20 71.0 3.8 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CCD23974.1 - 0.0034 17.2 0.1 0.0086 15.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain AA_permease_2 PF13520.1 CCD23975.1 - 4.6e-59 200.0 42.0 5.8e-59 199.7 29.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCD23975.1 - 9.2e-16 57.2 37.2 1.5e-15 56.5 25.8 1.3 1 1 0 1 1 1 1 Amino acid permease CRM1_C PF08767.6 CCD23976.1 - 2.8e-75 253.2 17.9 2.8e-75 253.2 12.4 3.1 5 0 0 5 5 5 1 CRM1 C terminal Xpo1 PF08389.7 CCD23976.1 - 1.7e-29 102.6 4.8 1.7e-29 102.6 3.3 4.8 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 CCD23976.1 - 2.7e-12 46.4 2.2 1.4e-11 44.1 0.4 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Sporozoite_P67 PF05642.6 CCD23976.1 - 0.54 8.0 0.2 0.88 7.3 0.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ribosomal_L6 PF00347.18 CCD23977.1 - 1.6e-21 76.5 2.1 1.2e-10 41.7 0.1 2.7 2 1 0 2 2 2 2 Ribosomal protein L6 Ribosomal_S4 PF00163.14 CCD23978.1 - 3.4e-26 91.4 1.9 7.2e-26 90.4 1.1 1.7 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCD23978.1 - 6.3e-14 51.1 0.0 7.5e-13 47.7 0.0 2.1 2 0 0 2 2 2 1 S4 domain Herpes_LAMP2 PF06126.6 CCD23978.1 - 0.035 12.5 0.1 0.042 12.2 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 SKG6 PF08693.5 CCD23979.1 - 1.8e-13 49.5 5.2 4.4e-13 48.3 3.6 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 CCD23979.1 - 0.00015 21.2 1.9 0.00021 20.8 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 CCD23979.1 - 0.00043 19.9 2.9 0.00059 19.5 0.0 2.6 2 0 0 2 2 2 1 TMEM154 protein family Shisa PF13908.1 CCD23979.1 - 0.0068 16.6 2.1 0.0068 16.6 1.4 3.5 3 1 1 4 4 4 1 Wnt and FGF inhibitory regulator 7tm_1 PF00001.16 CCD23979.1 - 0.085 11.9 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) EphA2_TM PF14575.1 CCD23979.1 - 0.12 12.8 0.1 0.12 12.8 0.0 2.9 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TRP PF06011.7 CCD23979.1 - 0.23 10.0 0.0 0.44 9.0 0.0 1.4 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF912 PF06024.7 CCD23979.1 - 0.52 10.3 0.0 0.52 10.3 0.0 4.0 4 1 1 5 5 5 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Pex24p PF06398.6 CCD23980.1 - 7.8e-63 212.4 0.2 1.1e-62 212.0 0.1 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin PRT_C PF08372.5 CCD23980.1 - 0.0099 15.3 4.7 0.11 12.0 0.4 3.1 3 1 0 3 3 3 1 Plant phosphoribosyltransferase C-terminal Reticulon PF02453.12 CCD23980.1 - 0.088 12.4 0.6 5 6.7 0.2 2.4 2 0 0 2 2 2 0 Reticulon Lectin_C PF00059.16 CCD23981.1 - 0.28 11.8 5.4 8.5 7.0 1.1 3.2 4 0 0 4 4 4 0 Lectin C-type domain Spo12 PF05032.7 CCD23982.1 - 2.1e-16 59.2 3.5 2.1e-16 59.2 2.5 2.1 2 1 1 3 3 3 1 Spo12 family PTCB-BRCT PF12738.2 CCD23983.1 - 2.7e-21 75.1 0.9 1.6e-13 50.2 0.0 3.6 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.21 CCD23983.1 - 3.6e-17 62.2 28.9 2.3e-07 30.8 0.3 7.4 8 1 0 8 8 8 3 BRCA1 C Terminus (BRCT) domain Inhibitor_I53 PF11714.3 CCD23984.1 - 0.038 13.9 0.0 0.047 13.6 0.0 1.2 1 0 0 1 1 1 0 Thrombin inhibitor Madanin DUF3881 PF12997.2 CCD23984.1 - 0.094 11.7 0.0 0.095 11.6 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3881) Nramp PF01566.13 CCD23984.1 - 0.13 11.0 0.0 0.14 10.9 0.0 1.0 1 0 0 1 1 1 0 Natural resistance-associated macrophage protein CAP PF00188.21 CCD23986.1 - 0.066 13.7 3.0 1.5 9.3 0.1 2.9 2 1 0 2 2 2 0 Cysteine-rich secretory protein family Ly49 PF08391.5 CCD23986.1 - 1.6 8.8 9.5 0.17 12.0 1.1 3.0 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region IncA PF04156.9 CCD23986.1 - 9.9 5.7 15.8 1.3 8.6 5.1 2.5 2 0 0 2 2 2 0 IncA protein SRI PF08236.6 CCD23987.1 - 0.042 13.8 2.1 0.39 10.6 0.8 2.5 2 1 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain SepQ PF06622.6 CCD23987.1 - 0.044 12.6 0.2 0.068 12.0 0.1 1.3 1 0 0 1 1 1 0 SepQ protein ANTH PF07651.11 CCD23988.1 - 9.9e-63 211.4 2.0 9.9e-63 211.4 1.4 1.9 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 CCD23988.1 - 0.00012 21.8 0.4 0.00048 19.9 0.0 2.3 2 0 0 2 2 2 1 ENTH domain MPC PF03650.8 CCD23989.1 - 2.4e-49 166.2 0.1 2.8e-49 166.0 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DDE_1 PF03184.14 CCD23990.1 - 4.2e-07 29.3 0.1 1.7e-06 27.3 0.0 2.0 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_10 PF04967.7 CCD23990.1 - 0.081 12.5 0.0 0.24 10.9 0.0 1.8 1 0 0 1 1 1 0 HTH DNA binding domain Glucosamine_iso PF01182.15 CCD23991.1 - 1.6e-49 168.3 0.0 2.1e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Dna2 PF08696.6 CCD23992.1 - 1.7e-60 203.9 0.1 3.5e-60 202.9 0.1 1.6 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.1 CCD23992.1 - 3.1e-50 170.3 1.3 4.2e-50 169.9 0.2 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CCD23992.1 - 2.5e-36 125.4 0.0 8.4e-18 64.8 0.0 2.8 1 1 1 2 2 2 2 AAA domain PDDEXK_1 PF12705.2 CCD23992.1 - 1.5e-10 40.9 0.0 2.7e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily AAA_30 PF13604.1 CCD23992.1 - 2.6e-10 40.2 0.0 1.8e-09 37.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCD23992.1 - 2e-07 30.6 0.0 4.1e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CCD23992.1 - 1.4e-06 27.9 3.7 0.0062 16.0 0.0 4.1 5 0 0 5 5 4 2 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.12 CCD23992.1 - 9.1e-05 22.4 0.1 0.00033 20.6 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function DUF83 AAA_18 PF13238.1 CCD23992.1 - 0.00071 19.8 3.7 0.0026 18.0 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.1 CCD23992.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain UvrD-helicase PF00580.16 CCD23992.1 - 0.0016 17.7 0.4 0.0067 15.7 0.0 2.4 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 CCD23992.1 - 0.0027 17.8 0.2 0.034 14.3 0.0 3.1 3 1 0 3 3 2 1 AAA domain MobB PF03205.9 CCD23992.1 - 0.0027 17.4 0.1 0.0086 15.7 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 CCD23992.1 - 0.0037 16.7 0.0 0.0087 15.5 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Miro PF08477.8 CCD23992.1 - 0.0038 17.7 0.0 0.084 13.3 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein CbiA PF01656.18 CCD23992.1 - 0.0042 16.5 0.1 0.076 12.4 0.0 2.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain T2SE PF00437.15 CCD23992.1 - 0.011 14.5 0.0 0.03 13.2 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein NTPase_1 PF03266.10 CCD23992.1 - 0.02 14.5 0.1 0.18 11.4 0.0 2.6 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.1 CCD23992.1 - 0.022 14.6 0.0 0.079 12.8 0.0 2.0 2 0 0 2 2 1 0 AAA domain Helicase_RecD PF05127.9 CCD23992.1 - 0.026 14.1 0.0 0.12 11.9 0.0 2.2 2 1 0 2 2 1 0 Helicase AAA_17 PF13207.1 CCD23992.1 - 0.036 14.8 0.0 0.19 12.5 0.0 2.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CCD23992.1 - 0.039 13.4 0.0 0.09 12.2 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 CCD23992.1 - 0.067 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PROCN PF08083.6 CCD23994.1 - 2e-219 728.1 15.1 3.3e-219 727.3 10.5 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CCD23994.1 - 1e-121 404.5 0.5 2.1e-121 403.4 0.3 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CCD23994.1 - 2.6e-88 293.4 0.5 5e-88 292.4 0.3 1.5 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CCD23994.1 - 3.4e-73 244.3 2.5 8.6e-73 243.0 1.7 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CCD23994.1 - 3.8e-65 217.5 0.1 1.4e-64 215.7 0.0 2.0 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 CCD23994.1 - 1.3e-47 160.6 0.0 3.8e-47 159.1 0.0 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 CCD23994.1 - 1.1e-43 147.0 1.0 3e-43 145.5 0.7 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 CCD23994.1 - 9.4e-05 22.1 0.1 0.00036 20.2 0.0 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease APC8 PF04049.8 CCD23995.1 - 4.4e-36 123.7 0.0 1.2e-35 122.3 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 CCD23995.1 - 2.2e-22 77.6 15.8 9.2e-06 25.0 0.0 8.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 CCD23995.1 - 5.1e-22 75.9 14.9 0.00049 19.7 0.0 9.3 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.1 CCD23995.1 - 3.2e-21 74.7 17.3 9.4e-11 41.2 0.0 6.7 3 1 4 7 7 7 5 TPR repeat TPR_8 PF13181.1 CCD23995.1 - 7e-21 72.3 14.8 0.00047 19.7 0.0 8.6 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 CCD23995.1 - 1.8e-13 50.1 15.3 0.0018 18.1 0.3 6.2 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCD23995.1 - 2.3e-12 46.3 0.0 0.0016 18.8 0.0 7.2 6 2 2 8 8 8 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCD23995.1 - 2e-11 44.2 0.5 1.9e-05 25.1 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCD23995.1 - 1.6e-08 33.7 0.3 1.1 9.1 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCD23995.1 - 7.1e-07 29.4 0.7 0.95 9.8 0.0 4.7 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCD23995.1 - 1.1e-06 28.2 7.9 0.00083 19.3 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat ChAPs PF09295.5 CCD23995.1 - 1.6e-06 27.1 0.0 4.6e-05 22.3 0.0 2.2 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) Apc3 PF12895.2 CCD23995.1 - 6.7e-06 26.1 25.8 0.002 18.2 0.6 5.7 3 1 4 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CCD23995.1 - 1.7e-05 24.5 0.1 0.25 11.2 0.0 3.7 2 1 0 3 3 3 2 Tetratricopeptide repeat RPN7 PF10602.4 CCD23995.1 - 0.0022 17.3 1.0 0.0022 17.3 0.7 2.3 2 0 0 2 2 2 1 26S proteasome subunit RPN7 TPR_6 PF13174.1 CCD23995.1 - 0.02 15.3 13.3 44 4.8 0.0 8.3 10 0 0 10 10 9 0 Tetratricopeptide repeat BTAD PF03704.12 CCD23995.1 - 0.052 13.8 0.1 0.16 12.2 0.0 1.8 2 0 0 2 2 1 0 Bacterial transcriptional activator domain TPR_10 PF13374.1 CCD23995.1 - 0.072 13.0 0.0 2.1 8.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.22 CCD23995.1 - 0.11 12.7 0.0 0.28 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PTH2 PF01981.11 CCD23995.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase PTH2 THP2 PF09432.5 CCD23996.1 - 6.6e-51 171.6 4.0 6.6e-51 171.6 2.7 2.1 2 0 0 2 2 2 1 Tho complex subunit THP2 GCN5L1 PF06320.8 CCD23996.1 - 0.013 15.3 1.7 0.036 13.8 1.2 1.7 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) IL5 PF02025.10 CCD23996.1 - 0.015 15.3 0.2 0.035 14.1 0.1 1.7 1 0 0 1 1 1 0 Interleukin 5 IL31 PF15209.1 CCD23996.1 - 0.03 13.9 2.5 0.068 12.7 0.6 2.3 1 1 0 2 2 2 0 Interleukin 31 Laminin_II PF06009.7 CCD23996.1 - 3.3 7.4 9.3 5.9 6.6 0.9 3.1 3 1 0 3 3 3 0 Laminin Domain II Uso1_p115_C PF04871.8 CCD23996.1 - 4.9 7.0 15.0 0.073 12.9 3.0 2.4 2 1 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region GTP1_OBG PF01018.17 CCD23997.1 - 2.4e-33 114.9 2.2 7.5e-24 84.1 1.3 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 CCD23997.1 - 1.2e-18 67.1 0.0 2.3e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCD23997.1 - 2e-07 30.4 0.0 6.3e-07 28.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 CCD23997.1 - 0.00015 21.0 0.0 0.00036 19.8 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CCD23997.1 - 0.0017 18.8 0.0 0.0074 16.7 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 CCD23997.1 - 0.11 11.9 0.0 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NMD3 PF04981.8 CCD23998.1 - 2.9e-76 255.6 1.4 2.9e-76 255.6 1.0 1.7 2 0 0 2 2 2 1 NMD3 family NinF PF05810.7 CCD23998.1 - 0.063 13.0 6.6 0.085 12.6 0.8 3.1 3 0 0 3 3 3 0 NinF protein DZR PF12773.2 CCD23998.1 - 0.87 9.4 7.7 6 6.7 3.9 2.8 2 1 1 3 3 3 0 Double zinc ribbon HypA PF01155.14 CCD23998.1 - 0.91 9.2 5.6 32 4.2 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FYVE PF01363.16 CCD23998.1 - 2.1 8.3 6.6 2.4 8.1 2.4 2.4 2 0 0 2 2 2 0 FYVE zinc finger zinc_ribbon_6 PF14599.1 CCD23998.1 - 3.2 7.6 9.3 0.65 9.8 0.1 3.4 2 1 1 3 3 3 0 Zinc-ribbon ThiF PF00899.16 CCD23999.1 - 1.2e-32 112.6 0.0 3.2e-32 111.1 0.0 1.8 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CCD23999.1 - 0.00039 20.5 0.1 0.00093 19.3 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 CCD23999.1 - 0.024 13.7 0.0 1.4 8.0 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 CCD23999.1 - 0.092 12.1 0.0 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Toprim PF01751.17 CCD23999.1 - 0.17 11.8 0.7 0.85 9.6 0.0 2.3 2 1 0 2 2 2 0 Toprim domain Proteasome PF00227.21 CCD24000.1 - 5.9e-54 182.2 0.1 7.9e-54 181.8 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCD24000.1 - 2e-13 49.3 0.1 4e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Spc97_Spc98 PF04130.8 CCD24001.1 - 2.3e-74 250.6 33.1 3.4e-74 250.1 22.9 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family Enolase_C PF00113.17 CCD24002.1 - 5.7e-151 501.5 0.0 7.7e-151 501.1 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CCD24002.1 - 2.6e-56 189.1 0.6 4.2e-56 188.5 0.4 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 CCD24002.1 - 0.016 15.7 0.0 0.062 13.8 0.0 2.1 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 CCD24002.1 - 0.022 14.7 0.1 0.079 12.9 0.0 2.1 2 0 0 2 2 2 0 Enolase C-terminal domain-like MAAL_C PF07476.6 CCD24002.1 - 0.12 11.3 0.3 0.52 9.1 0.1 1.9 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus UPF0150 PF03681.10 CCD24002.1 - 0.15 11.7 0.3 4.4 7.0 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0150) Ctr PF04145.10 CCD24003.1 - 8.8e-27 93.9 23.1 2.3e-25 89.3 13.3 2.4 2 1 0 2 2 2 1 Ctr copper transporter family Ni_hydr_CYTB PF01292.15 CCD24003.1 - 0.0044 16.4 1.1 0.0054 16.1 0.8 1.2 1 0 0 1 1 1 1 Prokaryotic cytochrome b561 FMO-like PF00743.14 CCD24004.1 - 7.7e-46 156.3 0.1 3.7e-37 127.7 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCD24004.1 - 2.8e-22 79.7 0.0 6.7e-22 78.5 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCD24004.1 - 4.6e-19 68.7 0.0 6.9e-18 64.9 0.0 2.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCD24004.1 - 1e-12 48.3 0.0 3.1e-12 46.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCD24004.1 - 1e-11 44.3 0.2 4.1e-10 39.1 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CCD24004.1 - 3.2e-06 27.0 0.0 1.2e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 CCD24004.1 - 4.6e-06 25.3 0.1 0.003 16.1 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.19 CCD24004.1 - 5.5e-06 25.5 0.0 0.0022 16.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 CCD24004.1 - 0.0012 18.0 0.3 0.018 14.1 0.0 2.4 3 0 0 3 3 3 1 Thi4 family Amino_oxidase PF01593.19 CCD24004.1 - 0.0027 16.8 0.2 0.0083 15.2 0.1 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Adaptin_N PF01602.15 CCD24004.1 - 0.023 13.0 0.0 0.038 12.3 0.0 1.2 1 0 0 1 1 1 0 Adaptin N terminal region NAD_Gly3P_dh_N PF01210.18 CCD24004.1 - 0.079 12.6 0.0 9.3 5.9 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 CCD24004.1 - 0.12 11.1 0.1 0.12 11.1 0.1 2.3 2 1 0 3 3 3 0 Glucose inhibited division protein A Pyr_redox PF00070.22 CCD24004.1 - 0.14 12.5 0.2 21 5.6 0.1 3.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 CCD24005.1 - 6.7e-32 110.3 0.1 6.7e-32 110.3 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD24005.1 - 3.3e-08 33.2 11.4 5.5e-08 32.5 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 CCD24005.1 - 0.27 11.4 9.1 0.62 10.2 6.3 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Oxidored_FMN PF00724.15 CCD24006.1 - 1.1e-131 438.8 0.0 1.3e-131 438.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Erv26 PF04148.8 CCD24007.1 - 1.2e-83 279.6 4.2 1.4e-83 279.4 2.9 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.15 CCD24007.1 - 0.6 9.6 5.0 0.4 10.1 0.9 2.3 2 1 1 3 3 3 0 Cytochrome C assembly protein VMA21 PF09446.5 CCD24007.1 - 2 8.3 8.3 1.9 8.4 0.2 2.4 2 0 0 2 2 2 0 VMA21-like domain RhoGAP PF00620.22 CCD24008.1 - 7.1e-05 22.4 0.0 0.00019 21.0 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain UBA_3 PF09288.5 CCD24008.1 - 0.027 14.0 1.5 0.16 11.6 0.0 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Seryl_tRNA_N PF02403.17 CCD24008.1 - 0.042 13.8 5.1 0.32 11.0 3.5 2.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain 6PGD PF00393.14 CCD24009.1 - 4.7e-133 442.8 0.0 5.9e-133 442.5 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CCD24009.1 - 2.5e-52 177.0 0.0 3.6e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CCD24009.1 - 0.011 16.0 0.2 0.023 15.1 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 CCD24009.1 - 0.033 14.2 0.0 0.18 11.8 0.0 2.2 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 CCD24009.1 - 0.14 11.3 0.1 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Retrotrans_gag PF03732.12 CCD24012.1 - 4.8e-05 23.3 0.1 8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein RVT_1 PF00078.22 CCD24013.1 - 3.9e-26 91.7 0.1 7.6e-26 90.7 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCD24013.1 - 4.7e-19 68.6 0.0 1.5e-18 66.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Peptidase_A2B PF12384.3 CCD24013.1 - 1.9e-17 63.1 0.1 4.1e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.1 CCD24013.1 - 7.8e-05 23.0 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CCD24013.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.5 CCD24013.1 - 0.0028 17.0 2.0 0.067 12.6 0.2 2.9 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Raptor_N PF14538.1 CCD24014.1 - 3.3e-65 218.6 0.0 3.3e-65 218.6 0.0 2.8 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 CCD24014.1 - 5.2e-07 29.2 1.4 0.039 14.0 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat WD40 PF00400.27 CCD24014.1 - 3.5e-06 26.6 2.1 0.11 12.4 0.0 6.0 6 0 0 6 6 6 1 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCD24014.1 - 4.5e-05 23.1 0.3 0.091 12.5 0.0 3.2 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region HEAT_2 PF13646.1 CCD24014.1 - 0.086 13.1 0.1 3.6 7.9 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats Elong_Iki1 PF10483.4 CCD24015.1 - 6.1e-85 284.9 0.5 6.9e-85 284.7 0.4 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 Gpi16 PF04113.9 CCD24016.1 - 8.7e-189 628.1 0.1 1.2e-188 627.7 0.1 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component HEAT_2 PF13646.1 CCD24017.1 - 4.8e-12 45.9 0.0 0.00043 20.4 0.0 7.2 3 2 3 7 7 7 1 HEAT repeats HEAT_EZ PF13513.1 CCD24017.1 - 3.6e-09 36.8 0.4 4.1 8.0 0.0 8.1 9 1 1 10 10 10 3 HEAT-like repeat HEAT PF02985.17 CCD24017.1 - 6.5e-08 32.0 12.3 0.79 9.9 0.0 9.4 11 0 0 11 11 11 2 HEAT repeat Vac14_Fab1_bd PF12755.2 CCD24017.1 - 7.2e-07 29.5 0.3 0.04 14.2 0.1 5.2 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CCD24017.1 - 0.0085 15.4 5.8 0.78 9.0 0.0 4.1 3 1 0 4 4 4 2 CLASP N terminal MMS19_N PF14500.1 CCD24017.1 - 0.051 12.8 2.0 0.34 10.1 0.2 3.2 5 0 0 5 5 5 0 Dos2-interacting transcription regulator of RNA-Pol-II Aminotran_4 PF01063.14 CCD24018.1 - 2.6e-24 85.9 0.0 3.9e-24 85.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV tRNA-synt_1g PF09334.6 CCD24019.1 - 1.9e-147 491.0 0.1 2.5e-147 490.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.5 CCD24019.1 - 1.2e-28 99.9 4.2 1.2e-28 99.9 2.9 2.0 2 0 0 2 2 2 1 MetRS-N binding domain tRNA-synt_1 PF00133.17 CCD24019.1 - 2.7e-11 42.2 0.5 9e-05 20.6 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCD24019.1 - 0.0036 17.0 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CCD24019.1 - 0.013 14.6 0.0 0.04 13.0 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain DEAD PF00270.24 CCD24020.1 - 7.3e-46 155.7 0.4 4.5e-45 153.1 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD24020.1 - 1.3e-21 76.2 0.0 2.7e-21 75.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCD24020.1 - 1.7e-20 72.2 0.5 3.4e-20 71.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CCD24020.1 - 0.003 17.4 0.3 0.013 15.3 0.0 2.1 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 CCD24020.1 - 0.0037 16.5 0.0 0.01 15.1 0.0 1.7 1 1 0 1 1 1 1 SecA DEAD-like domain AAA_22 PF13401.1 CCD24020.1 - 0.025 14.7 1.2 0.12 12.4 0.8 2.3 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 CCD24021.1 - 1.7e-50 171.6 3.6 1.2e-48 165.4 1.9 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24021.1 - 6.8e-23 81.0 0.2 2.8e-20 72.4 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCD24021.1 - 0.011 14.7 0.1 0.55 9.1 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Got1 PF04178.7 CCD24022.1 - 2.8e-19 69.3 12.1 3.4e-19 69.1 8.4 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 CCD24022.1 - 0.00013 21.0 9.2 0.00013 21.0 6.4 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF973) DUF373 PF04123.8 CCD24022.1 - 1.2 8.0 3.8 1.3 7.9 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF1129 PF06570.6 CCD24022.1 - 2.5 7.3 4.4 3.2 6.9 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) PEMT PF04191.8 CCD24022.1 - 3.5 7.7 8.2 1 9.4 0.8 2.7 1 1 1 2 2 2 0 Phospholipid methyltransferase DUF4401 PF14351.1 CCD24022.1 - 4.6 6.1 12.2 7 5.5 7.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4401) Amidase PF01425.16 CCD24023.1 - 4e-102 342.3 0.0 4.8e-102 342.0 0.0 1.1 1 0 0 1 1 1 1 Amidase Dynamitin PF04912.9 CCD24024.1 - 1.7e-15 56.7 32.5 2.3e-15 56.3 22.6 1.2 1 0 0 1 1 1 1 Dynamitin Feld-I_B PF09252.5 CCD24024.1 - 0.24 11.3 1.9 3.5 7.5 0.2 2.7 2 0 0 2 2 2 0 Allergen Fel d I-B chain Phasin PF05597.6 CCD24024.1 - 5.2 6.8 12.0 0.27 11.0 1.6 3.3 3 1 0 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Raptor_N PF14538.1 CCD24024.1 - 8 6.2 9.6 1.5 8.6 0.7 3.1 2 1 2 4 4 4 0 Raptor N-terminal CASPase like domain DUF2406 PF10295.4 CCD24025.1 - 2.2e-25 88.9 0.1 5.2e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) Aminotran_1_2 PF00155.16 CCD24026.1 - 3.9e-65 220.1 0.1 4.8e-65 219.8 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_S10 PF00450.17 CCD24027.1 - 5.8e-128 427.5 0.2 7.2e-128 427.2 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 CCD24027.1 - 8.2e-18 64.6 0.1 1.4e-17 63.9 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide V_cholerae_RfbT PF05575.6 CCD24027.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Vibrio cholerae RfbT protein DUF3591 PF12157.3 CCD24029.1 - 4e-189 628.7 0.3 4e-189 628.7 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 CCD24029.1 - 4.4e-05 23.0 0.4 0.0001 21.9 0.3 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 CCD24029.1 - 0.17 11.8 0.4 0.38 10.7 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle Cyclin_N PF00134.18 CCD24030.1 - 1.2e-10 40.9 1.3 3.5e-10 39.5 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain PPTA PF01239.17 CCD24031.1 - 1.4e-41 138.1 16.6 1.3e-09 36.9 0.3 6.0 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat Vps53_N PF04100.7 CCD24032.1 - 3.2e-75 253.3 16.1 3.2e-75 253.3 11.1 2.1 2 1 0 2 2 2 1 Vps53-like, N-terminal Fib_alpha PF08702.5 CCD24032.1 - 5.5 7.0 17.5 3.1 7.9 0.1 3.6 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family Cpn60_TCP1 PF00118.19 CCD24033.1 - 4.1e-137 457.7 7.2 4.7e-137 457.5 5.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PUF PF00806.14 CCD24034.1 - 2.4e-32 108.5 11.1 6.2e-05 22.2 0.1 9.2 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat FANCI_S1-cap PF14674.1 CCD24034.1 - 0.042 13.8 0.1 0.13 12.3 0.1 1.9 1 0 0 1 1 1 0 FANCI solenoid 1 cap DUF3294 PF07957.6 CCD24035.1 - 5e-72 241.9 8.8 5.6e-72 241.7 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) Tricorn_C1 PF14684.1 CCD24035.1 - 0.11 12.4 2.0 12 5.8 0.0 3.2 3 0 0 3 3 3 0 Tricorn protease C1 domain HsbA PF12296.3 CCD24035.1 - 0.12 12.2 2.4 0.22 11.3 1.6 1.5 1 0 0 1 1 1 0 Hydrophobic surface binding protein A OmpH PF03938.9 CCD24035.1 - 0.13 12.2 7.3 0.11 12.3 0.6 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) AAA_31 PF13614.1 CCD24035.1 - 0.13 12.1 0.8 0.41 10.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain Cas_APE2256 PF09651.5 CCD24035.1 - 0.4 10.4 3.0 1.9 8.2 0.2 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) SPX PF03105.14 CCD24035.1 - 0.41 10.3 11.4 3.4 7.3 7.9 2.0 1 1 0 1 1 1 0 SPX domain MutS_III PF05192.13 CCD24035.1 - 0.46 10.2 3.4 0.79 9.4 2.3 1.3 1 1 0 1 1 1 0 MutS domain III Troponin PF00992.15 CCD24035.1 - 2.7 8.0 12.2 0.73 9.9 1.1 2.8 2 1 1 3 3 3 0 Troponin Pox_A_type_inc PF04508.7 CCD24035.1 - 5.6 7.0 7.3 0.78 9.6 0.1 3.3 3 1 1 4 4 4 0 Viral A-type inclusion protein repeat Iron_permease PF04120.7 CCD24035.1 - 9.9 5.7 7.4 6.6 6.3 0.1 2.9 2 2 1 3 3 3 0 Low affinity iron permease LTV PF04180.9 CCD24036.1 - 5.4e-125 418.2 41.8 6.7e-125 417.9 29.0 1.1 1 0 0 1 1 1 1 Low temperature viability protein RNA_pol_Rbc25 PF08292.7 CCD24037.1 - 7.1e-45 152.1 2.9 2e-44 150.6 2.0 1.7 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CCD24037.1 - 6.6e-19 67.8 0.0 9.9e-19 67.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CCD24037.1 - 0.012 15.6 0.2 0.047 13.7 0.1 2.2 1 1 0 1 1 1 0 S1 RNA binding domain AAA PF00004.24 CCD24038.1 - 1e-40 138.9 0.0 1.7e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCD24038.1 - 2.8e-06 27.4 0.0 0.00074 19.6 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 CCD24038.1 - 1.5e-05 24.7 0.1 7.5e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCD24038.1 - 7.4e-05 22.7 0.0 0.00022 21.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCD24038.1 - 9.3e-05 22.4 0.0 0.00036 20.5 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 CCD24038.1 - 0.00084 18.3 0.0 0.0015 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CCD24038.1 - 0.00087 20.0 0.1 0.0021 18.8 0.0 1.8 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CCD24038.1 - 0.0025 16.8 0.0 0.0042 16.1 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCD24038.1 - 0.005 16.5 0.2 0.0097 15.6 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 CCD24038.1 - 0.0077 16.2 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCD24038.1 - 0.011 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 CCD24038.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCD24038.1 - 0.014 15.6 0.1 0.047 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CCD24038.1 - 0.016 15.1 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CCD24038.1 - 0.022 14.8 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.17 CCD24038.1 - 0.022 14.9 0.0 0.045 13.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 CCD24038.1 - 0.024 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 CCD24038.1 - 0.027 14.0 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CCD24038.1 - 0.039 13.1 0.0 0.088 11.9 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 CCD24038.1 - 0.041 12.6 0.0 0.063 11.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Arch_ATPase PF01637.13 CCD24038.1 - 0.044 13.4 0.0 3.6 7.2 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase AAA_24 PF13479.1 CCD24038.1 - 0.066 12.7 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CCD24038.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Aa_trans PF01490.13 CCD24039.1 - 7.3e-97 324.4 34.7 8.9e-97 324.1 24.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein CENP-B_dimeris PF09026.5 CCD24039.1 - 0.91 9.7 7.0 2.4 8.4 4.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Pro_dh PF01619.13 CCD24040.1 - 1.3e-56 191.9 0.0 1.9e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase FAD_binding_2 PF00890.19 CCD24041.1 - 3e-123 411.7 2.8 3.7e-123 411.4 1.9 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CCD24041.1 - 2.1e-47 160.2 0.2 3.1e-47 159.6 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 CCD24041.1 - 1.3e-06 28.4 0.3 0.00022 21.1 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCD24041.1 - 5.3e-06 25.6 0.2 0.00081 18.5 0.0 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.17 CCD24041.1 - 1.1e-05 24.5 2.7 0.0035 16.2 1.5 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 CCD24041.1 - 1.1e-05 24.5 0.5 0.00038 19.4 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCD24041.1 - 0.0037 16.3 0.3 0.0085 15.1 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 CCD24041.1 - 0.038 12.4 1.0 0.13 10.7 0.1 2.3 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox_3 PF13738.1 CCD24041.1 - 0.44 10.5 2.3 1.9 8.5 0.5 2.5 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.23 CCD24042.1 - 5.9e-13 48.6 0.8 6.5e-12 45.2 0.5 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DBR1 PF05011.8 CCD24042.1 - 2.2e-08 34.1 1.6 3.2e-08 33.5 0.2 1.9 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain NAD_binding_1 PF00175.16 CCD24043.1 - 6.1e-23 81.4 0.0 9.1e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCD24043.1 - 6.9e-20 71.0 0.0 1.4e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 CCD24043.1 - 1.4e-06 28.3 0.0 0.00015 21.6 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_6 PF00970.19 CCD24044.1 - 6.6e-23 80.6 0.0 1e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CCD24044.1 - 4.5e-18 65.8 0.0 6.6e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CCD24044.1 - 6.2e-05 22.9 0.0 9.3e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Carb_kinase PF01256.12 CCD24045.1 - 1.2e-70 237.5 0.0 8.6e-70 234.7 0.0 1.9 1 1 1 2 2 2 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 CCD24045.1 - 4.5e-06 26.0 0.0 9.5e-06 24.9 0.0 1.5 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.10 CCD24045.1 - 0.077 12.1 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family His_Phos_1 PF00300.17 CCD24046.1 - 8.1e-44 149.4 0.0 1.1e-43 149.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SRPRB PF09439.5 CCD24047.1 - 1.8e-53 180.4 1.1 2.3e-53 180.0 0.8 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CCD24047.1 - 2.4e-09 36.6 0.0 3.3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCD24047.1 - 3.9e-07 30.0 0.2 7.7e-07 29.0 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 CCD24047.1 - 0.00029 20.6 0.6 0.0014 18.3 0.3 2.1 1 1 0 1 1 1 1 Archaeal ATPase FeoB_N PF02421.13 CCD24047.1 - 0.00038 19.7 0.1 0.00093 18.5 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 CCD24047.1 - 0.0057 16.1 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CCD24047.1 - 0.013 15.1 0.1 0.063 12.9 0.1 2.2 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 CCD24047.1 - 0.017 14.6 0.2 0.27 10.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 CCD24047.1 - 0.022 14.6 0.0 0.04 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCD24047.1 - 0.025 14.8 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 CCD24047.1 - 0.029 14.3 4.6 0.069 13.1 3.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 CCD24047.1 - 0.061 13.6 7.2 0.44 10.8 5.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCD24047.1 - 0.081 13.0 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Rsm22 PF09243.5 CCD24048.1 - 7.6e-30 103.8 0.2 2.1e-09 36.8 0.0 4.3 3 1 1 4 4 4 4 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 CCD24048.1 - 0.00064 19.4 0.0 0.0018 17.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD24048.1 - 0.0047 17.5 0.0 0.016 15.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ribosomal_S27e PF01667.12 CCD24049.1 - 2.1e-30 104.0 2.7 2.9e-30 103.5 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CCD24049.1 - 4.3e-05 23.3 0.7 5.3e-05 23.0 0.5 1.1 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 CCD24049.1 - 0.051 12.8 3.8 0.074 12.3 2.6 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 CCD24049.1 - 0.13 11.9 1.3 6.2 6.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CCD24049.1 - 0.14 11.9 1.3 6.3 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.20 CCD24050.1 - 5.5e-69 232.1 0.0 6.9e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24050.1 - 2.9e-35 121.5 0.0 4e-35 121.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCD24050.1 - 0.087 12.5 0.1 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CCD24050.1 - 0.12 11.3 0.2 0.3 10.1 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Calcipressin PF04847.7 CCD24051.1 - 1e-15 57.8 1.3 1.8e-15 57.0 0.8 1.6 1 1 0 1 1 1 1 Calcipressin Peptidase_M1 PF01433.15 CCD24052.1 - 2.5e-143 477.8 1.4 3.7e-143 477.3 1.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CCD24052.1 - 1.2e-87 294.2 0.9 7.9e-87 291.5 0.4 2.1 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CCD24052.1 - 6.4e-21 74.7 0.4 1.4e-20 73.6 0.3 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily adh_short PF00106.20 CCD24053.1 - 2.5e-07 30.7 0.1 7.2e-07 29.2 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 CCD24053.1 - 0.00068 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 CCD24053.1 - 0.00083 19.4 0.1 0.0021 18.0 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CCD24053.1 - 0.0018 17.9 0.0 0.003 17.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCD24053.1 - 0.0018 17.7 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family FAD_binding_1 PF00667.15 CCD24054.1 - 1.2e-69 234.0 0.0 1.9e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCD24054.1 - 2.7e-28 98.7 0.2 4.5e-28 98.0 0.1 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCD24054.1 - 5e-22 78.5 0.0 1.5e-21 77.0 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MAGE PF01454.14 CCD24055.1 - 1.7e-38 131.9 0.7 2.2e-38 131.5 0.5 1.2 1 0 0 1 1 1 1 MAGE family YtzH PF14165.1 CCD24055.1 - 0.013 15.6 1.4 2.1 8.6 0.0 2.8 1 1 1 2 2 2 0 YtzH-like protein Inositol_P PF00459.20 CCD24056.1 - 4.4e-70 236.0 0.0 5.3e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Gamma-thionin PF00304.15 CCD24056.1 - 0.56 10.2 2.6 1.3 9.1 1.8 1.6 1 1 0 1 1 1 0 Gamma-thionin family DUF836 PF05768.9 CCD24057.1 - 5.6e-18 64.9 1.5 7.2e-18 64.6 1.1 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 CCD24057.1 - 5.6e-05 23.0 0.1 0.00013 21.8 0.1 1.7 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 CCD24057.1 - 0.012 15.8 0.5 0.015 15.4 0.3 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain AhpC-TSA PF00578.16 CCD24057.1 - 0.047 13.3 0.1 0.056 13.1 0.1 1.1 1 0 0 1 1 1 0 AhpC/TSA family IncFII_repA PF02387.10 CCD24057.1 - 0.056 12.5 0.9 0.065 12.3 0.6 1.1 1 0 0 1 1 1 0 IncFII RepA protein family Reo_sigmaC PF04582.7 CCD24058.1 - 1.8 7.6 33.2 0.15 11.1 5.1 4.3 2 1 2 4 4 4 0 Reovirus sigma C capsid protein PAP2 PF01569.16 CCD24059.1 - 6.5e-20 71.1 0.9 6.5e-20 71.1 0.6 2.0 1 1 1 2 2 2 1 PAP2 superfamily DUF4131 PF13567.1 CCD24059.1 - 0.014 14.7 3.1 2.4 7.5 2.9 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Colicin_V PF02674.11 CCD24059.1 - 0.19 11.5 8.4 1 9.2 0.0 3.3 2 1 1 3 3 3 0 Colicin V production protein MerC PF03203.9 CCD24059.1 - 0.35 11.2 5.8 4.3 7.7 4.0 2.3 1 1 0 1 1 1 0 MerC mercury resistance protein TcpE PF12648.2 CCD24059.1 - 0.4 10.8 9.6 0.14 12.3 4.3 2.0 1 1 1 2 2 2 0 TcpE family 2TM PF13239.1 CCD24059.1 - 0.88 9.6 8.7 0.14 12.2 2.3 2.3 3 0 0 3 3 3 0 2TM domain RseC_MucC PF04246.7 CCD24059.1 - 1.2 8.6 3.9 1.1 8.8 0.9 2.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Abi PF02517.11 CCD24059.1 - 9.6 6.4 12.0 0.94 9.6 3.6 2.3 2 1 0 2 2 2 0 CAAX protease self-immunity HGTP_anticodon2 PF12745.2 CCD24060.1 - 1.5e-96 322.7 6.2 1.5e-96 322.7 4.3 2.9 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 CCD24060.1 - 2.5e-66 223.4 8.9 4.9e-45 153.7 0.0 4.8 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24060.1 - 9.1e-38 129.7 0.1 2.6e-21 75.8 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 CCD24060.1 - 1.1e-17 63.8 1.5 4.5e-17 61.9 1.1 2.2 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 CCD24060.1 - 2.4e-13 49.8 0.0 5.2e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 Histidyl-tRNA synthetase APH PF01636.18 CCD24060.1 - 0.01 15.5 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CCD24060.1 - 0.019 13.9 0.0 0.06 12.3 0.0 1.7 2 0 0 2 2 2 0 Kinase-like CTD_bind PF04818.8 CCD24061.1 - 2.6e-21 75.6 0.2 6.5e-21 74.3 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. CTK3 PF12243.3 CCD24061.1 - 1.2e-06 28.1 4.3 2.3e-05 24.0 0.2 2.2 2 0 0 2 2 2 2 CTD kinase subunit gamma CTK3 Carbpep_Y_N PF05388.6 CCD24061.1 - 0.01 15.9 1.4 0.039 14.1 0.1 2.6 1 1 2 3 3 3 0 Carboxypeptidase Y pro-peptide DASH_Dam1 PF08653.5 CCD24061.1 - 0.043 13.5 0.3 1.2 8.9 0.0 3.2 3 0 0 3 3 3 0 DASH complex subunit Dam1 DUF4614 PF15391.1 CCD24061.1 - 1.6 8.4 15.0 0.64 9.7 7.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) DEAD PF00270.24 CCD24062.1 - 1e-24 86.9 0.1 3.3e-24 85.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.5 CCD24062.1 - 2.8e-15 56.6 0.1 7.6e-15 55.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 CCD24062.1 - 1e-12 47.6 0.1 9.2e-12 44.6 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.6 CCD24062.1 - 0.0012 18.8 0.2 0.0044 16.9 0.1 2.1 1 0 0 1 1 1 1 DNA replication factor CDT1 like TFR_dimer PF04253.10 CCD24062.1 - 0.079 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 Transferrin receptor-like dimerisation domain SRX PF09201.5 CCD24063.1 - 5.5e-48 162.3 2.0 1.2e-47 161.3 1.4 1.6 1 0 0 1 1 1 1 SRX SRP54 PF00448.17 CCD24063.1 - 5.5e-48 163.0 0.2 1.1e-45 155.4 0.1 2.4 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 CCD24063.1 - 2e-07 31.0 0.4 8e-07 29.0 0.3 2.1 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain CbiA PF01656.18 CCD24063.1 - 2.3e-06 27.1 0.0 5.6e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP-alpha_N PF04086.8 CCD24063.1 - 3.5e-06 26.6 0.4 8.5e-06 25.3 0.3 1.6 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal ArgK PF03308.11 CCD24063.1 - 0.00063 18.5 0.1 0.002 16.9 0.0 1.9 2 1 0 2 2 2 1 ArgK protein ArsA_ATPase PF02374.10 CCD24063.1 - 0.0029 16.7 0.1 0.2 10.6 0.0 2.8 3 0 0 3 3 3 1 Anion-transporting ATPase Zeta_toxin PF06414.7 CCD24063.1 - 0.0031 16.6 0.3 0.062 12.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin Fer4_NifH PF00142.13 CCD24063.1 - 0.0034 16.6 0.1 0.011 14.9 0.1 1.9 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 CCD24063.1 - 0.0044 17.1 0.0 0.036 14.2 0.0 2.6 1 1 1 2 2 2 1 AAA domain MobB PF03205.9 CCD24063.1 - 0.0075 15.9 0.0 0.022 14.4 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CCD24063.1 - 0.017 14.9 0.3 0.26 11.1 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.1 CCD24063.1 - 0.023 14.6 0.0 0.065 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 CCD24063.1 - 2.2 8.0 8.3 1.2 8.9 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function DUF87 zf-HIT PF04438.11 CCD24064.1 - 4.8e-09 35.6 11.2 8.9e-09 34.8 7.7 1.5 1 0 0 1 1 1 1 HIT zinc finger FOP_dimer PF09398.5 CCD24064.1 - 0.025 14.5 0.2 0.078 12.9 0.1 1.9 1 0 0 1 1 1 0 FOP N terminal dimerisation domain RNB PF00773.14 CCD24065.1 - 5.3e-54 183.6 3.5 5.3e-54 183.6 2.4 2.4 2 0 0 2 2 2 1 RNB domain OB_RNB PF08206.6 CCD24065.1 - 0.0015 17.9 0.0 0.85 9.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease B OB domain Pyridoxal_deC PF00282.14 CCD24066.1 - 2.2e-18 65.8 0.0 4.2e-18 64.9 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 CCD24066.1 - 1.6e-05 24.1 0.0 2.5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CCD24066.1 - 0.00039 19.2 0.0 0.013 14.2 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V HDA2-3 PF11496.3 CCD24067.1 - 2.9e-64 216.7 30.4 2.9e-64 216.7 21.1 3.8 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 Mhr1 PF12829.2 CCD24068.1 - 1.8e-26 91.7 1.4 4.2e-26 90.5 1.0 1.6 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination OSCP PF00213.13 CCD24069.1 - 2.8e-39 134.7 2.6 3.3e-39 134.4 1.8 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit RPAP3_C PF13877.1 CCD24069.1 - 0.038 13.9 0.5 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 Potential Monad-binding region of RPAP3 AATF-Che1 PF13339.1 CCD24070.1 - 1.3e-27 96.5 11.1 1.3e-27 96.5 7.7 3.9 4 2 1 5 5 5 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 CCD24070.1 - 7.8e-25 86.8 0.6 7.8e-25 86.8 0.4 4.2 4 0 0 4 4 4 2 Apoptosis-antagonizing transcription factor, C-terminal RNase_H2-Ydr279 PF09468.5 CCD24071.1 - 4e-49 167.4 11.6 5e-49 167.1 8.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF1886 PF09171.5 CCD24071.1 - 0.018 14.0 0.2 0.028 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1886) AA_kinase PF00696.23 CCD24072.1 - 1.2e-35 123.1 0.7 2e-35 122.4 0.5 1.3 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CCD24072.1 - 6.5e-19 67.4 0.0 1.5e-18 66.3 0.0 1.7 1 0 0 1 1 1 1 PUA domain DUF4224 PF13986.1 CCD24072.1 - 0.12 11.9 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) CPSF_A PF03178.10 CCD24073.1 - 1.3e-80 270.9 0.1 1.5e-79 267.4 0.0 2.6 2 0 0 2 2 2 1 CPSF A subunit region DUF1743 PF08489.6 CCD24074.1 - 0.088 12.5 0.1 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1743) GHMP_kinases_N PF00288.21 CCD24075.1 - 6e-15 55.0 0.2 6.7e-14 51.7 0.1 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCD24075.1 - 7e-07 29.3 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal PIG-F PF06699.6 CCD24076.1 - 1.7e-43 148.8 20.0 1.6e-42 145.6 13.9 1.9 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF1673 PF07895.6 CCD24076.1 - 0.02 14.4 2.0 0.027 13.9 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) TauE PF01925.14 CCD24076.1 - 0.5 9.7 9.4 7.2 5.9 6.0 2.1 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Zn_clus PF00172.13 CCD24077.1 - 4.3e-07 29.7 7.5 7.3e-07 28.9 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 CCD24078.1 - 7.3e-43 146.4 0.3 9.3e-43 146.1 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HIT PF01230.18 CCD24079.1 - 3.4e-25 88.4 0.1 6.3e-25 87.5 0.0 1.4 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 CCD24079.1 - 2.8e-05 24.3 0.0 4.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding LRR_8 PF13855.1 CCD24080.1 - 0.072 12.8 2.7 1.1 9.0 0.2 3.7 4 0 0 4 4 4 0 Leucine rich repeat PMT PF02366.13 CCD24081.1 - 9e-17 61.2 22.2 9e-17 61.2 15.4 3.3 3 1 1 4 4 4 2 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCD24081.1 - 8.5e-06 25.4 0.0 1.8e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 MIR domain Med21 PF11221.3 CCD24082.1 - 1.1e-46 158.3 2.2 1.1e-46 158.3 1.5 1.9 1 1 1 2 2 2 1 Subunit 21 of Mediator complex Med9 PF07544.8 CCD24082.1 - 0.0022 17.6 0.7 0.0065 16.1 0.5 1.9 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 Sipho_Gp157 PF05565.6 CCD24082.1 - 0.02 14.4 0.9 0.02 14.4 0.6 1.6 2 0 0 2 2 2 0 Siphovirus Gp157 TMCO5 PF14992.1 CCD24082.1 - 0.036 13.2 0.4 0.036 13.2 0.2 1.8 2 0 0 2 2 2 0 TMCO5 family RVT_N PF13655.1 CCD24082.1 - 0.06 13.4 1.6 0.085 12.9 0.2 1.9 3 0 0 3 3 3 0 N-terminal domain of reverse transcriptase Phyto_Pns9_10 PF05878.6 CCD24082.1 - 0.14 11.1 2.2 0.17 10.8 1.5 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF1342 PF07072.6 CCD24082.1 - 0.36 10.4 2.2 0.26 10.9 0.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) Flagellin_C PF00700.16 CCD24082.1 - 0.77 9.9 6.2 0.25 11.5 1.4 2.4 2 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region FYVE PF01363.16 CCD24083.1 - 1.1e-17 63.6 13.4 1.1e-17 63.6 9.3 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 CCD24083.1 - 5.2e-10 38.9 3.3 5.2e-10 38.9 2.3 3.9 3 1 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.1 CCD24083.1 - 0.0035 17.0 1.9 0.0035 17.0 1.3 3.5 4 0 0 4 4 4 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CCD24083.1 - 0.0047 16.5 4.6 0.0047 16.5 3.2 4.7 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCD24083.1 - 0.014 15.4 5.5 0.014 15.4 3.8 3.6 3 2 0 3 3 3 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CCD24083.1 - 0.018 15.0 4.2 0.018 15.0 2.9 4.5 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Brix PF04427.13 CCD24084.1 - 2.1e-59 200.3 3.8 3e-59 199.8 2.7 1.2 1 0 0 1 1 1 1 Brix domain DEAD PF00270.24 CCD24085.1 - 4.3e-47 159.7 0.0 9.6e-47 158.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD24085.1 - 1.2e-26 92.3 0.0 3.2e-26 90.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD24085.1 - 1.3e-05 25.1 6.7 0.00015 21.6 0.0 3.0 1 1 1 2 2 1 1 Type III restriction enzyme, res subunit Neur_chan_memb PF02932.11 CCD24085.1 - 0.018 14.9 0.4 0.026 14.4 0.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Otopetrin PF03189.8 CCD24085.1 - 0.5 9.3 2.8 4.5 6.1 0.1 2.1 2 0 0 2 2 2 0 Otopetrin Tim54 PF11711.3 CCD24085.1 - 0.89 8.0 7.2 1.3 7.5 5.0 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SUFU_C PF12470.3 CCD24085.1 - 1 8.8 5.9 1.7 8.1 4.1 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain YqfQ PF14181.1 CCD24085.1 - 1.3 9.0 10.1 2.2 8.3 7.0 1.4 1 0 0 1 1 1 0 YqfQ-like protein FAM176 PF14851.1 CCD24085.1 - 2.1 8.0 8.9 4.4 6.9 6.2 1.5 1 0 0 1 1 1 0 FAM176 family BTV_NS2 PF04514.7 CCD24085.1 - 3 6.6 13.0 4.6 6.0 9.0 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 RP-C_C PF11800.3 CCD24085.1 - 4.1 7.0 9.9 7.3 6.2 6.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region PBD PF00786.23 CCD24086.1 - 0.23 11.8 2.7 0.24 11.8 0.3 2.2 2 0 0 2 2 2 0 P21-Rho-binding domain Ins_P5_2-kin PF06090.7 CCD24088.1 - 1.8e-41 142.1 1.9 2.3e-41 141.8 1.3 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Methyltransf_23 PF13489.1 CCD24089.1 - 1.6e-14 53.9 0.0 2.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCD24089.1 - 6.7e-12 45.7 0.0 2e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCD24089.1 - 2.4e-09 36.6 1.1 0.00011 21.3 0.0 3.2 2 1 1 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CCD24089.1 - 4.2e-07 29.6 0.0 2.3e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCD24089.1 - 2.1e-06 28.0 0.0 0.00013 22.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD24089.1 - 4.8e-06 27.1 0.0 1.3e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD24089.1 - 1.1e-05 25.7 0.0 2.4e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cyclin PF08613.6 CCD24090.1 - 1.7e-13 51.2 5.5 3.9e-13 50.0 3.8 1.6 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCD24090.1 - 3.2e-05 23.5 0.6 3.2e-05 23.5 0.4 1.9 2 1 0 2 2 2 1 Cyclin, N-terminal domain Phage_int_SAM_4 PF13495.1 CCD24090.1 - 0.045 14.0 0.1 0.095 13.0 0.1 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain DnaI_N PF07319.6 CCD24090.1 - 0.1 12.8 0.1 0.18 12.0 0.1 1.4 1 0 0 1 1 1 0 Primosomal protein DnaI N-terminus Scs3p PF10261.4 CCD24091.1 - 8.4e-39 133.0 14.0 3.4e-38 131.0 9.7 1.8 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM DUF2776 PF10951.3 CCD24091.1 - 0.013 14.5 5.5 0.026 13.6 3.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2776) PAP2 PF01569.16 CCD24091.1 - 0.033 13.8 1.7 0.077 12.6 1.1 1.7 1 1 0 1 1 1 0 PAP2 superfamily DUF872 PF05915.7 CCD24091.1 - 0.56 10.0 3.5 17 5.3 0.8 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) ATP_synt_I PF03899.10 CCD24091.1 - 4.7 7.4 9.9 1.3 9.1 0.4 2.6 2 1 0 2 2 2 0 ATP synthase I chain Ubiq-assoc PF09145.5 CCD24092.1 - 7.5e-22 76.9 2.2 1.6e-21 75.8 1.5 1.5 1 0 0 1 1 1 1 Ubiquitin-associated TPR_11 PF13414.1 CCD24092.1 - 6e-12 45.0 0.4 6.5e-09 35.3 0.0 3.0 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 CCD24092.1 - 5.9e-10 38.3 3.7 0.012 15.2 0.0 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCD24092.1 - 2e-08 33.5 1.2 0.094 12.6 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCD24092.1 - 5.6e-08 32.6 0.2 6.7e-05 22.7 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCD24092.1 - 0.026 14.2 8.2 0.69 9.8 0.7 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCD24092.1 - 0.069 13.6 0.1 1.1 9.8 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCD24092.1 - 0.079 12.7 0.0 79 3.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCD24092.1 - 0.2 12.3 0.0 22 6.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DASH_Dad4 PF08650.5 CCD24093.1 - 1.3e-35 121.1 7.9 1.4e-35 121.0 5.5 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 Nsp1_C PF05064.8 CCD24093.1 - 0.0025 17.4 0.8 0.0027 17.3 0.5 1.1 1 0 0 1 1 1 1 Nsp1-like C-terminal region NPV_P10 PF05531.7 CCD24093.1 - 0.0061 16.7 0.7 0.0071 16.5 0.5 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein UPF0122 PF04297.9 CCD24093.1 - 0.017 15.1 0.8 0.018 15.0 0.5 1.1 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like FAM117 PF15388.1 CCD24093.1 - 0.017 14.3 0.7 0.018 14.2 0.5 1.1 1 0 0 1 1 1 0 Protein Family FAM117 DUF3251 PF11622.3 CCD24093.1 - 0.032 13.6 0.9 0.037 13.4 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) DUF327 PF03885.8 CCD24093.1 - 0.034 13.9 0.6 0.039 13.7 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF327) DUF2335 PF10097.4 CCD24093.1 - 0.039 13.5 0.2 0.054 13.1 0.1 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2335) Laminin_II PF06009.7 CCD24093.1 - 0.051 13.3 0.4 0.055 13.2 0.3 1.2 1 0 0 1 1 1 0 Laminin Domain II DASH_Dad1 PF08649.5 CCD24093.1 - 0.063 12.9 2.4 0.091 12.4 1.7 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad1 TMF_TATA_bd PF12325.3 CCD24093.1 - 0.071 12.8 0.6 0.073 12.7 0.4 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Prominin PF05478.6 CCD24093.1 - 0.1 10.0 0.5 0.1 10.1 0.4 1.0 1 0 0 1 1 1 0 Prominin DivIVA PF05103.8 CCD24093.1 - 0.12 12.3 0.7 0.14 12.2 0.5 1.1 1 0 0 1 1 1 0 DivIVA protein Asparaginase PF00710.15 CCD24094.1 - 9.1e-70 234.9 0.0 1.1e-69 234.7 0.0 1.1 1 0 0 1 1 1 1 Asparaginase HMG_box PF00505.14 CCD24095.1 - 3.7e-06 27.1 5.9 4.4e-05 23.6 0.0 3.3 3 0 0 3 3 3 2 HMG (high mobility group) box RP-C_C PF11800.3 CCD24095.1 - 0.52 9.9 5.8 0.97 9.0 4.0 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region PBP PF01161.15 CCD24096.1 - 4.9e-12 45.9 0.0 8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ATP-synt_E PF05680.7 CCD24097.1 - 1.1e-16 60.5 0.0 1.1e-16 60.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain FYVE PF01363.16 CCD24098.1 - 1.8e-19 69.4 23.9 1.5e-17 63.2 2.9 3.3 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 CCD24098.1 - 0.00016 21.1 1.4 0.00016 21.1 0.9 3.1 4 0 0 4 4 3 1 Rabenosyn Rab binding domain NPV_P10 PF05531.7 CCD24098.1 - 0.005 17.0 1.1 0.005 17.0 0.8 2.9 3 1 0 3 3 2 1 Nucleopolyhedrovirus P10 protein zf-C2H2 PF00096.21 CCD24098.1 - 0.0092 16.2 0.2 0.0092 16.2 0.2 5.1 4 1 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD24098.1 - 0.02 15.1 0.3 0.02 15.1 0.2 5.0 4 1 1 5 5 5 0 C2H2-type zinc finger zf-Di19 PF05605.7 CCD24098.1 - 0.038 14.1 0.4 0.038 14.1 0.3 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 CCD24098.1 - 0.068 13.3 3.6 0.11 12.7 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Prok-RING_1 PF14446.1 CCD24098.1 - 0.09 12.5 23.9 0.062 13.0 3.9 4.3 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PX PF00787.19 CCD24098.1 - 0.11 12.2 2.1 19 5.1 0.1 3.2 3 0 0 3 3 3 0 PX domain zf-C2H2_6 PF13912.1 CCD24098.1 - 0.2 11.6 0.1 0.2 11.6 0.1 4.9 5 0 0 5 5 4 0 C2H2-type zinc finger zinc_ribbon_5 PF13719.1 CCD24098.1 - 0.25 10.9 5.6 5.1 6.7 0.0 3.9 3 0 0 3 3 3 0 zinc-ribbon domain HypA PF01155.14 CCD24098.1 - 0.57 9.8 13.3 1.8 8.2 1.2 3.1 3 0 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-C2HC_2 PF13913.1 CCD24098.1 - 0.87 9.3 16.6 1.3 8.7 0.0 4.8 5 1 0 5 5 5 0 zinc-finger of a C2HC-type Cep57_MT_bd PF06657.8 CCD24098.1 - 2.8 7.9 9.9 3 7.8 0.5 3.4 3 1 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 CorA PF01544.13 CCD24098.1 - 9.4 5.1 10.9 1.7 7.5 0.5 3.0 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein WD40 PF00400.27 CCD24099.1 - 5.3e-18 64.1 12.6 0.0011 18.7 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Cnd3 PF12719.2 CCD24100.1 - 8.6e-95 317.1 7.5 1.1e-94 316.7 3.7 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 CCD24100.1 - 8.2e-06 26.0 0.0 0.00028 21.1 0.0 3.5 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 CCD24100.1 - 0.00019 21.2 0.1 5.2 7.4 0.0 4.5 4 0 0 4 4 4 2 HEAT repeat GRAM PF02893.15 CCD24101.1 - 1.3e-20 72.6 0.0 3.1e-20 71.4 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Skp1 PF01466.14 CCD24102.1 - 7.5e-37 125.2 0.3 1.3e-36 124.4 0.2 1.4 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CCD24102.1 - 5e-14 52.1 0.3 2.5e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain Herpes_UL32 PF06070.6 CCD24102.1 - 0.69 8.3 5.5 0.8 8.0 3.8 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DNA_pol_phi PF04931.8 CCD24102.1 - 1.1 7.0 7.1 1.2 6.8 4.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peroxin-3 PF04882.7 CCD24103.1 - 1.9e-81 274.0 23.2 4e-81 272.9 16.1 1.4 1 1 0 1 1 1 1 Peroxin-3 Thioredoxin_7 PF13899.1 CCD24104.1 - 5.5e-19 67.9 0.0 1.1e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBA_4 PF14555.1 CCD24104.1 - 8.6e-15 53.9 0.3 1.9e-14 52.9 0.2 1.6 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 CCD24104.1 - 1.7e-14 53.6 0.0 4.2e-14 52.3 0.0 1.7 1 0 0 1 1 1 1 UBX domain C2-set PF05790.10 CCD24104.1 - 0.00012 21.9 0.0 0.00031 20.6 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin C2-set domain Thioredox_DsbH PF03190.10 CCD24104.1 - 0.023 14.4 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Peptidase_C13 PF01650.13 CCD24105.1 - 1.2e-47 162.3 0.4 1.6e-47 161.9 0.3 1.1 1 0 0 1 1 1 1 Peptidase C13 family ResIII PF04851.10 CCD24106.1 - 6.6e-25 88.0 0.2 6.6e-25 88.0 0.2 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCD24106.1 - 4.9e-19 68.4 0.2 1.3e-18 67.0 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD24106.1 - 7.9e-13 48.0 0.1 3.2e-12 46.1 0.1 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCD24106.1 - 7.9e-06 24.8 2.0 1e-05 24.5 0.0 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CCD24106.1 - 0.0016 18.6 1.0 0.01 15.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain Flavi_DEAD PF07652.9 CCD24106.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_11 PF13086.1 CCD24106.1 - 0.012 15.1 4.4 0.47 9.9 0.2 3.4 3 1 1 4 4 4 0 AAA domain Helicase_C_2 PF13307.1 CCD24106.1 - 0.039 13.8 1.8 0.069 13.0 0.0 2.3 3 0 0 3 3 3 0 Helicase C-terminal domain STE PF02200.11 CCD24107.1 - 8.4e-59 196.5 3.1 1.7e-58 195.5 2.1 1.5 1 0 0 1 1 1 1 STE like transcription factor Tcf25 PF04910.9 CCD24108.1 - 5.5e-85 285.4 1.5 1e-84 284.6 1.0 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TraE PF05309.6 CCD24108.1 - 0.03 13.4 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 TraE protein Ipi1_N PF12333.3 CCD24109.1 - 3.4e-27 94.3 0.1 1.6e-26 92.2 0.0 2.1 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation Oxidored_FMN PF00724.15 CCD24110.1 - 7.1e-10 38.4 0.0 8.4e-10 38.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family SNF2_N PF00176.18 CCD24111.1 - 8.8e-78 261.1 0.4 2.1e-77 259.8 0.3 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain HSA PF07529.8 CCD24111.1 - 2e-16 59.5 4.6 2e-16 59.5 3.2 2.7 1 1 1 2 2 2 1 HSA Helicase_C PF00271.26 CCD24111.1 - 1.6e-14 53.5 0.0 5.2e-14 51.8 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD24111.1 - 6e-07 29.1 0.0 2.7e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase MMR_HSR1 PF01926.18 CCD24112.1 - 6.9e-11 42.1 0.3 2.1e-10 40.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCD24112.1 - 1.9e-05 23.8 0.1 5.1e-05 22.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 CCD24112.1 - 0.0011 18.2 0.0 0.0022 17.2 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CCD24112.1 - 0.0043 16.5 0.3 0.012 15.1 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CCD24112.1 - 0.051 12.8 0.1 0.11 11.7 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Ribosomal_S15 PF00312.17 CCD24113.1 - 9.5e-28 95.7 0.6 9.5e-28 95.7 0.4 1.9 2 0 0 2 2 2 1 Ribosomal protein S15 TraB PF01963.12 CCD24113.1 - 0.0096 15.3 0.7 0.013 14.9 0.5 1.3 1 0 0 1 1 1 1 TraB family UPF0542 PF15086.1 CCD24113.1 - 0.04 13.6 1.0 0.14 11.9 0.7 1.9 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 MatE PF01554.13 CCD24114.1 - 2.7e-60 202.6 38.4 6.2e-35 120.2 6.7 3.5 4 0 0 4 4 4 2 MatE Fcf1 PF04900.7 CCD24115.1 - 9.2e-38 128.4 0.1 9.2e-38 128.4 0.1 1.8 2 0 0 2 2 2 1 Fcf1 Sugar_tr PF00083.19 CCD24116.1 - 5.3e-174 579.0 38.4 6e-174 578.8 26.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD24116.1 - 1.2e-26 93.2 31.9 1.9e-26 92.6 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF202 PF02656.10 CCD24116.1 - 4.3 7.6 7.5 66 3.8 0.0 4.4 2 2 1 3 3 3 0 Domain of unknown function (DUF202) Sugar_tr PF00083.19 CCD24117.1 - 4.4e-172 572.7 35.6 5e-172 572.5 24.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD24117.1 - 6.5e-31 107.3 31.9 2.1e-29 102.3 17.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Herpes_US9 PF06072.6 CCD24117.1 - 8.1 6.3 9.0 3.3 7.6 0.1 3.7 2 1 1 3 3 3 0 Alphaherpesvirus tegument protein US9 Svf1 PF08622.5 CCD24118.1 - 1.2e-136 454.9 8.2 1.8e-136 454.4 5.7 1.2 1 0 0 1 1 1 1 Svf1-like DUF2138 PF09909.4 CCD24118.1 - 0.14 10.2 1.2 0.21 9.6 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2138) DUF913 PF06025.7 CCD24118.1 - 0.16 10.6 1.8 0.28 9.9 1.2 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Daxx PF03344.10 CCD24118.1 - 0.37 9.2 12.5 0.54 8.6 8.7 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 CCD24118.1 - 0.39 8.6 6.5 0.56 8.1 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein IncA PF04156.9 CCD24118.1 - 1.8 8.1 6.6 2.9 7.4 4.6 1.2 1 0 0 1 1 1 0 IncA protein FAM176 PF14851.1 CCD24118.1 - 8 6.1 10.2 4.8 6.8 5.1 2.0 2 0 0 2 2 2 0 FAM176 family Sod_Fe_C PF02777.13 CCD24119.1 - 1.1e-11 44.4 1.9 2.3e-06 27.3 0.1 2.9 2 1 0 3 3 3 2 Iron/manganese superoxide dismutases, C-terminal domain Semialdhyde_dhC PF02774.13 CCD24119.1 - 0.051 13.4 0.0 0.074 12.9 0.0 1.2 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain Pal1 PF08316.6 CCD24120.1 - 1.4e-49 168.1 3.9 1.4e-49 168.1 2.7 3.5 2 1 2 4 4 4 1 Pal1 cell morphology protein Zip PF02535.17 CCD24120.1 - 0.71 8.8 6.9 1.2 8.1 4.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Asp PF00026.18 CCD24121.1 - 1e-30 107.1 4.1 5.3e-30 104.7 2.8 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCD24121.1 - 0.0004 20.3 0.8 0.002 18.1 0.1 2.3 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal FAT PF02259.18 CCD24122.1 - 5.3e-72 242.7 7.5 9.8e-72 241.8 5.2 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 CCD24122.1 - 3.5e-42 144.4 0.5 1e-41 142.9 0.3 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CCD24122.1 - 0.015 14.7 0.0 0.046 13.1 0.0 1.9 1 0 0 1 1 1 0 FATC domain TPR_11 PF13414.1 CCD24122.1 - 0.18 11.4 3.2 0.4 10.3 0.2 2.8 3 0 0 3 3 3 0 TPR repeat DUF111 PF01969.12 CCD24124.1 - 0.15 10.8 0.3 0.23 10.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF111 PQ-loop PF04193.9 CCD24125.1 - 5.4e-36 121.9 11.6 5e-18 64.4 0.9 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF3816 PF12822.2 CCD24125.1 - 0.00059 19.7 6.3 0.013 15.3 4.4 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3816) MtN3_slv PF03083.11 CCD24125.1 - 0.051 13.4 8.2 0.32 10.9 0.4 3.5 2 2 1 3 3 3 0 Sugar efflux transporter for intercellular exchange Pyr_redox_2 PF07992.9 CCD24126.1 - 1.4e-25 90.3 0.1 2e-25 89.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCD24126.1 - 6.6e-19 68.1 0.2 8.7e-15 54.9 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCD24126.1 - 8e-11 42.3 0.0 8.9e-06 25.9 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCD24126.1 - 1.1e-06 27.8 0.1 4.1e-05 22.7 0.0 2.5 2 1 0 2 2 2 1 Thi4 family GIDA PF01134.17 CCD24126.1 - 5.7e-05 22.1 1.8 0.24 10.2 0.0 3.5 3 1 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_7 PF13241.1 CCD24126.1 - 7.3e-05 22.9 0.0 0.026 14.7 0.0 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding Shikimate_DH PF01488.15 CCD24126.1 - 0.00018 21.5 0.1 0.2 11.7 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 CCD24126.1 - 0.00027 20.9 0.0 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CCD24126.1 - 0.0035 16.2 0.0 3.6 6.4 0.0 3.4 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 CCD24126.1 - 0.014 14.4 0.0 4.5 6.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 CCD24126.1 - 0.021 13.7 0.0 0.44 9.3 0.0 2.6 2 1 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCD24126.1 - 0.033 13.0 1.8 1.6 7.5 0.1 2.5 2 1 0 2 2 2 0 FAD binding domain DEAD PF00270.24 CCD24127.1 - 2.8e-37 127.7 0.1 1.9e-36 125.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD24127.1 - 3e-18 65.4 0.0 6.5e-18 64.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD24127.1 - 1.2e-05 25.1 0.0 3.6e-05 23.6 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit KRAB PF01352.22 CCD24128.1 - 0.02 14.3 0.0 0.052 13.0 0.0 1.6 1 0 0 1 1 1 0 KRAB box CoaE PF01121.15 CCD24129.1 - 4.6e-61 205.3 0.0 5.6e-61 205.0 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 CCD24129.1 - 7e-10 39.7 0.1 1.2e-09 38.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCD24129.1 - 1.2e-06 28.8 0.2 3.1e-06 27.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCD24129.1 - 2.3e-05 24.4 0.0 5.1e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 CCD24129.1 - 3.4e-05 23.7 0.1 0.00042 20.2 0.0 2.1 2 0 0 2 2 2 1 Shikimate kinase AAA_33 PF13671.1 CCD24129.1 - 7.6e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 CCD24129.1 - 0.00036 20.4 0.1 0.00089 19.2 0.0 1.7 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_14 PF13173.1 CCD24129.1 - 0.002 18.0 0.0 0.004 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain PRK PF00485.13 CCD24129.1 - 0.0057 16.2 0.0 0.14 11.7 0.0 2.2 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family tRNA_lig_kinase PF08303.6 CCD24129.1 - 0.012 15.4 0.1 0.027 14.3 0.0 1.6 2 0 0 2 2 2 0 tRNA ligase kinase domain ABC_tran PF00005.22 CCD24129.1 - 0.037 14.3 0.2 0.066 13.5 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 CCD24129.1 - 0.057 13.5 0.0 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain Glu_syn_central PF04898.9 CCD24129.1 - 0.062 12.5 0.2 0.094 11.9 0.2 1.2 1 0 0 1 1 1 0 Glutamate synthase central domain ApbA_C PF08546.6 CCD24130.1 - 1.3e-09 38.1 0.2 2.2e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal PAZ_siRNAbind PF12212.3 CCD24130.1 - 0.04 13.5 1.1 0.76 9.4 0.2 2.5 2 0 0 2 2 2 0 Piwi/Argonaute/Zwille siRNA-binding domain DUF2188 PF09954.4 CCD24130.1 - 0.14 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) FHA PF00498.21 CCD24132.1 - 6.8e-17 61.3 0.3 2.3e-16 59.6 0.2 2.1 1 0 0 1 1 1 1 FHA domain TFR_dimer PF04253.10 CCD24132.1 - 3e-05 23.5 0.7 9e-05 22.0 0.5 1.9 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Tir_receptor_N PF07490.6 CCD24132.1 - 0.015 14.9 0.8 0.033 13.8 0.6 1.5 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus SAD_SRA PF02182.12 CCD24132.1 - 0.13 11.5 1.8 0.28 10.4 0.2 2.1 2 0 0 2 2 2 0 SAD/SRA domain DASH_Spc19 PF08287.6 CCD24133.1 - 4.9e-40 136.6 10.8 5.5e-40 136.4 7.5 1.0 1 0 0 1 1 1 1 Spc19 RNA_pol_Rpb5_C PF01191.14 CCD24133.1 - 0.057 13.0 0.1 0.095 12.2 0.1 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Not3 PF04065.10 CCD24133.1 - 0.091 12.0 4.1 0.079 12.2 1.3 2.0 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component DUF4407 PF14362.1 CCD24133.1 - 0.2 10.5 1.6 0.28 10.0 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) H-kinase_dim PF02895.9 CCD24133.1 - 0.56 10.5 7.2 25 5.2 0.6 3.2 3 0 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain Glutaredoxin2_C PF04399.8 CCD24133.1 - 0.69 9.5 3.4 0.26 10.8 0.3 1.8 2 1 1 3 3 3 0 Glutaredoxin 2, C terminal domain NPV_P10 PF05531.7 CCD24133.1 - 0.7 10.1 6.2 9.1 6.6 1.4 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Prefoldin PF02996.12 CCD24133.1 - 1.2 8.7 8.9 1.3 8.6 0.3 3.0 3 0 0 3 3 3 0 Prefoldin subunit TBCA PF02970.11 CCD24133.1 - 2.1 8.4 7.2 0.53 10.4 0.4 2.7 2 1 1 3 3 3 0 Tubulin binding cofactor A DUF972 PF06156.8 CCD24133.1 - 3.1 8.1 10.2 8 6.8 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF972) bZIP_2 PF07716.10 CCD24133.1 - 4.8 7.0 9.7 22 4.9 1.8 3.2 3 0 0 3 3 3 0 Basic region leucine zipper DUF948 PF06103.6 CCD24133.1 - 4.9 7.0 7.4 5.3 6.9 0.4 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) YPEB PF14620.1 CCD24133.1 - 9.6 5.1 8.6 8.8 5.2 1.0 2.2 1 1 1 2 2 2 0 YpeB sporulation Coq4 PF05019.8 CCD24134.1 - 6.5e-95 316.2 0.0 8.8e-95 315.8 0.0 1.2 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Transp_cyt_pur PF02133.10 CCD24135.1 - 1.9e-70 237.6 44.0 2.4e-70 237.2 30.5 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cation_efflux PF01545.16 CCD24136.1 - 6.5e-51 173.0 5.6 6.5e-51 173.0 3.9 3.3 4 1 0 4 4 4 1 Cation efflux family DUF2946 PF11162.3 CCD24136.1 - 0.16 12.1 7.6 0.15 12.2 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) Zip PF02535.17 CCD24136.1 - 0.18 10.7 28.2 60 2.4 17.4 3.8 2 1 0 2 2 2 0 ZIP Zinc transporter FAM60A PF15396.1 CCD24136.1 - 2 8.0 7.1 11 5.7 0.5 2.3 2 0 0 2 2 2 0 Protein Family FAM60A EST1_DNA_bind PF10373.4 CCD24137.1 - 2e-35 122.3 11.9 7.3e-35 120.5 8.3 2.0 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CCD24137.1 - 5.1e-21 75.0 3.6 5.1e-21 75.0 2.5 4.2 5 1 0 5 5 5 1 Telomerase activating protein Est1 Zn_clus PF00172.13 CCD24138.1 - 1.4e-08 34.5 9.4 2.5e-08 33.6 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cytokin_check_N PF10407.4 CCD24138.1 - 0.0038 16.7 1.2 0.011 15.3 0.8 1.7 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus PIP5K PF01504.13 CCD24139.1 - 5e-85 284.6 5.1 5e-85 284.6 3.5 2.1 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase W2 PF02020.13 CCD24140.1 - 4.1e-15 55.5 4.8 4.1e-15 55.5 3.3 2.3 2 1 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 CCD24140.1 - 4.1e-10 38.6 23.5 0.0083 15.5 2.2 4.8 3 2 2 5 5 5 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 CCD24140.1 - 5.7e-09 35.6 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CCD24140.1 - 0.0074 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Ras PF00071.17 CCD24141.1 - 4.1e-48 162.8 0.0 4.8e-48 162.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD24141.1 - 1.3e-12 48.2 0.0 1.8e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCD24141.1 - 3.1e-06 26.5 0.0 4.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Cpn60_TCP1 PF00118.19 CCD24142.1 - 4.5e-143 477.3 15.7 5.2e-143 477.1 10.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Zn_clus PF00172.13 CCD24143.1 - 1.6e-07 31.0 12.9 2.5e-07 30.4 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aha1_N PF09229.6 CCD24144.1 - 4.6e-36 123.6 0.2 4.6e-36 123.6 0.1 2.2 3 0 0 3 3 3 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CCD24144.1 - 5.9e-12 45.7 0.1 1e-11 45.0 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein DUF3362 PF11842.3 CCD24144.1 - 0.032 14.1 0.5 0.064 13.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) zf-C2H2 PF00096.21 CCD24145.1 - 1.5e-11 43.9 6.1 2.1e-05 24.5 0.5 3.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD24145.1 - 5.5e-09 35.7 7.2 0.00043 20.4 0.2 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD24145.1 - 2.7e-08 33.6 7.3 3.7e-07 30.1 2.7 2.9 2 0 0 2 2 2 1 Zinc-finger double domain zf-met PF12874.2 CCD24145.1 - 0.004 17.3 5.5 0.55 10.5 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCD24145.1 - 0.013 15.6 1.3 1 9.5 0.2 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCD24145.1 - 0.056 13.3 3.8 0.31 10.9 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 CCD24145.1 - 0.14 12.3 1.9 0.42 10.7 1.3 1.9 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Rad9_Rad53_bind PF08605.5 CCD24146.1 - 1.3e-40 138.2 0.2 2.8e-40 137.1 0.2 1.6 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 CCD24146.1 - 4.3e-09 36.3 0.1 1.6e-08 34.6 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Septin PF00735.13 CCD24147.1 - 6.2e-68 228.8 10.7 9e-68 228.3 7.4 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCD24147.1 - 0.00013 21.8 1.6 0.0013 18.6 1.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 CCD24147.1 - 0.0013 18.2 0.0 0.0022 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain FtsK_SpoIIIE PF01580.13 CCD24147.1 - 0.0031 17.0 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 CCD24147.1 - 0.0034 17.8 0.2 0.013 15.9 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CCD24147.1 - 0.004 17.3 0.0 0.0094 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCD24147.1 - 0.0048 17.1 0.6 0.026 14.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 CCD24147.1 - 0.0061 15.7 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CCD24147.1 - 0.0062 16.7 0.0 0.029 14.5 0.0 2.2 2 0 0 2 2 1 1 RNA helicase Dynamin_N PF00350.18 CCD24147.1 - 0.0078 16.0 0.4 0.0078 16.0 0.3 2.1 2 1 0 2 2 2 1 Dynamin family AAA_5 PF07728.9 CCD24147.1 - 0.016 14.9 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MRP-S24 PF14955.1 CCD24147.1 - 0.031 14.1 0.1 0.087 12.6 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 AAA_29 PF13555.1 CCD24147.1 - 0.034 13.6 0.0 0.081 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 CCD24147.1 - 0.035 13.0 0.1 0.064 12.1 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 CCD24147.1 - 0.053 12.9 0.0 0.098 12.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 CCD24147.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CCD24147.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF3658 PF12395.3 CCD24147.1 - 0.068 12.7 0.6 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function AAA_25 PF13481.1 CCD24147.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 CCD24147.1 - 0.44 9.9 4.1 0.85 9.0 0.0 2.6 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain F-box PF00646.28 CCD24148.1 - 1.2e-05 24.7 0.0 2.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 CCD24148.1 - 0.0018 17.9 0.0 0.0043 16.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like PRKCSH-like PF12999.2 CCD24149.1 - 9e-37 126.3 4.5 9e-37 126.3 3.1 2.4 2 0 0 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CCD24149.1 - 6.7e-16 58.1 1.4 6.7e-16 58.1 1.0 3.1 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein RNA_pol_Rpb1_5 PF04998.12 CCD24149.1 - 0.28 10.4 8.1 0.16 11.2 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 Svf1 PF08622.5 CCD24150.1 - 3.4e-92 308.9 6.3 4e-92 308.6 4.4 1.1 1 0 0 1 1 1 1 Svf1-like Secretin_N_2 PF07655.8 CCD24150.1 - 0.22 11.9 7.9 0.077 13.3 2.3 2.6 3 0 0 3 3 3 0 Secretin N-terminal domain VIT1 PF01988.14 CCD24151.1 - 1.2e-58 198.1 1.0 1.5e-58 197.7 0.7 1.1 1 0 0 1 1 1 1 VIT family Histone PF00125.19 CCD24152.1 - 1.1e-21 76.6 0.3 1.6e-21 76.1 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCD24152.1 - 6.8e-06 26.0 0.1 1.5e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CCD24152.1 - 0.0013 18.9 0.0 0.0023 18.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 CCD24152.1 - 0.0077 14.9 3.0 0.0092 14.6 2.1 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein RNA_pol_Rpb1_1 PF04997.7 CCD24152.1 - 0.03 13.5 0.9 0.032 13.4 0.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 CENP-W PF15510.1 CCD24152.1 - 0.08 12.9 0.8 1.3 9.0 0.5 2.1 1 1 0 1 1 1 0 Centromere kinetochore component W DUF869 PF05911.6 CCD24152.1 - 0.1 10.8 2.3 0.11 10.7 1.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Histone PF00125.19 CCD24153.1 - 6.3e-26 90.2 0.0 8.8e-26 89.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCD24153.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ADK PF00406.17 CCD24154.1 - 2.4e-61 206.0 0.0 2.8e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CCD24154.1 - 1.1e-15 56.9 0.0 3.2e-15 55.5 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_17 PF13207.1 CCD24154.1 - 2e-08 35.0 0.0 3.4e-08 34.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCD24154.1 - 1.4e-07 31.5 0.0 2.7e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCD24154.1 - 0.00014 22.1 0.0 0.00025 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCD24154.1 - 0.0051 15.9 0.0 0.0092 15.0 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 CCD24154.1 - 0.095 12.0 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_22 PF13401.1 CCD24154.1 - 0.11 12.5 0.0 0.28 11.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain PAH PF02671.16 CCD24156.1 - 0.11 12.0 2.5 0.4 10.3 0.4 2.8 2 0 0 2 2 2 0 Paired amphipathic helix repeat CFIA_Pcf11 PF11526.3 CCD24157.1 - 1.1e-19 70.3 10.2 1.1e-19 70.3 7.1 3.3 3 1 0 3 3 3 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.14 CCD24157.1 - 0.00081 19.0 0.2 0.0036 16.9 0.0 2.2 2 0 0 2 2 2 1 VHS domain ASFV_J13L PF05568.6 CCD24157.1 - 4.2 6.8 6.6 0.96 8.9 0.3 2.2 2 0 0 2 2 2 0 African swine fever virus J13L protein zf-C2H2_6 PF13912.1 CCD24157.1 - 5.6 7.0 5.6 5.5 7.0 0.5 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3767 PF12597.3 CCD24159.1 - 4.5e-37 126.3 1.1 5e-37 126.1 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3767) Aminotran_1_2 PF00155.16 CCD24160.1 - 1.1e-70 238.3 0.2 2.4e-70 237.3 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CCD24160.1 - 7.8e-09 34.2 0.0 1.4e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CCD24160.1 - 2.3e-05 23.3 0.0 0.00015 20.6 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 CCD24160.1 - 0.00061 18.9 0.4 0.0024 16.9 0.3 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Mucin PF01456.12 CCD24160.1 - 0.21 11.3 11.5 0.35 10.6 8.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Alpha_GJ PF03229.8 CCD24160.1 - 0.79 10.0 9.1 1.7 9.0 6.3 1.4 1 0 0 1 1 1 0 Alphavirus glycoprotein J Reticulon PF02453.12 CCD24161.1 - 3e-39 134.3 4.2 4.1e-39 133.9 2.9 1.2 1 0 0 1 1 1 1 Reticulon DUF95 PF01944.12 CCD24161.1 - 0.013 15.1 0.5 0.023 14.3 0.4 1.5 1 1 0 1 1 1 0 Integral membrane protein DUF95 DUF2547 PF10818.3 CCD24161.1 - 0.04 14.5 1.1 0.45 11.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) NUC130_3NT PF08158.7 CCD24161.1 - 0.49 10.7 2.8 6 7.2 0.2 2.5 2 0 0 2 2 2 0 NUC130/3NT domain Aconitase PF00330.15 CCD24162.1 - 2.9e-72 243.6 0.3 2.5e-69 233.9 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCD24162.1 - 2.3e-32 111.8 0.5 6.2e-32 110.4 0.0 1.9 2 0 0 2 2 2 1 Aconitase C-terminal domain Flavokinase PF01687.12 CCD24164.1 - 4.5e-30 104.0 0.0 5.7e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Riboflavin kinase Ribosomal_L5_C PF00673.16 CCD24165.1 - 3.4e-22 77.9 0.0 7e-22 76.9 0.0 1.6 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CCD24165.1 - 1.4e-06 27.9 0.1 3e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Adaptin_N PF01602.15 CCD24166.1 - 1.4e-105 353.6 15.9 2.4e-105 352.8 11.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CCD24166.1 - 3e-58 195.1 0.0 7e-58 193.9 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CCD24166.1 - 1.4e-51 173.8 0.2 4.4e-51 172.2 0.1 1.9 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CCD24166.1 - 1.1e-07 32.0 7.7 0.00041 20.5 0.0 4.1 3 1 1 4 4 4 3 HEAT repeats Cnd1 PF12717.2 CCD24166.1 - 0.0049 16.7 8.2 0.52 10.1 0.1 3.9 2 2 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 CCD24166.1 - 0.0058 16.6 1.5 3.1 8.1 0.0 4.8 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 CCD24166.1 - 1.1 9.8 5.7 12 6.5 0.0 4.8 6 1 0 6 6 6 0 HEAT-like repeat Ino80_Iec3 PF14612.1 CCD24168.1 - 0.0071 16.4 3.7 0.013 15.5 2.6 1.4 1 0 0 1 1 1 1 IEC3 subunit of the Ino80 complex, chromatin re-modelling SRI PF08236.6 CCD24168.1 - 0.0088 15.9 1.4 0.039 13.8 0.1 2.5 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Ribosomal_L7Ae PF01248.21 CCD24169.1 - 3.6e-27 93.6 0.5 5.7e-27 93.0 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF3692 PF12469.3 CCD24169.1 - 0.094 12.9 2.3 0.37 11.0 1.6 1.9 1 1 0 1 1 1 0 CRISPR-associated protein Amidase PF01425.16 CCD24170.1 - 2e-83 280.6 0.0 2.4e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 Amidase GH-E PF14410.1 CCD24170.1 - 0.023 14.8 0.4 0.28 11.3 0.0 2.6 3 0 0 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues DUF1160 PF06648.6 CCD24170.1 - 0.055 13.2 0.4 0.13 12.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) DEAD PF00270.24 CCD24171.1 - 1.3e-41 141.9 0.4 2.3e-39 134.6 0.1 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD24171.1 - 3.4e-25 87.7 0.4 1.2e-24 85.9 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD24171.1 - 0.00068 19.5 0.1 0.0036 17.1 0.0 2.3 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCD24171.1 - 0.063 13.4 5.2 0.12 12.5 0.1 3.0 3 1 0 3 3 3 0 AAA domain DUF2986 PF11661.3 CCD24171.1 - 0.074 13.3 0.6 0.2 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) TPR_11 PF13414.1 CCD24172.1 - 1.9e-23 81.8 12.7 2.6e-12 46.1 0.5 4.3 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 CCD24172.1 - 1e-17 62.9 10.4 6.9e-07 28.6 0.1 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCD24172.1 - 1.3e-17 62.2 7.9 5.4e-05 22.8 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCD24172.1 - 9.5e-16 56.6 15.2 0.00039 20.3 0.1 5.9 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCD24172.1 - 5.6e-13 48.2 0.2 0.0066 16.9 0.0 5.2 2 2 3 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.1 CCD24172.1 - 8.8e-10 38.5 1.6 0.00075 19.5 0.0 4.8 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCD24172.1 - 1.4e-09 38.3 0.0 0.00021 21.8 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCD24172.1 - 2.3e-07 30.6 6.3 5.8e-05 22.9 0.1 3.6 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCD24172.1 - 4.7e-07 30.0 4.8 0.02 15.2 0.0 4.4 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCD24172.1 - 1.6e-06 27.8 0.1 0.017 14.9 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCD24172.1 - 2.6e-06 26.8 12.4 0.042 13.6 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCD24172.1 - 4.8e-06 26.6 1.6 1.2 9.7 0.0 5.3 6 0 0 6 6 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CCD24172.1 - 0.00022 21.2 5.4 0.016 15.2 0.2 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 CCD24172.1 - 0.0031 17.1 0.0 2.3 8.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCD24172.1 - 0.01 14.9 0.7 0.021 13.9 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat BTAD PF03704.12 CCD24172.1 - 0.026 14.8 0.0 0.37 11.1 0.0 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain MIT PF04212.13 CCD24172.1 - 0.035 13.9 0.2 14 5.6 0.0 3.1 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Glyco_transf_34 PF05637.7 CCD24173.1 - 1e-72 244.5 0.2 1.4e-72 244.0 0.2 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 CCD24173.1 - 0.011 15.0 0.0 0.83 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF273 Sybindin PF04099.7 CCD24174.1 - 4.9e-35 120.3 5.1 3.4e-14 52.7 0.4 3.0 2 1 1 3 3 3 3 Sybindin-like family Sedlin_N PF04628.8 CCD24174.1 - 3.1e-08 33.5 0.7 1.6e-07 31.2 0.2 2.0 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region Pkinase PF00069.20 CCD24175.1 - 5.2e-47 160.1 0.7 1.2e-45 155.6 0.5 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24175.1 - 5.6e-22 78.0 0.3 2.2e-21 76.0 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD24175.1 - 2.2e-07 30.1 0.0 1.7e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCD24175.1 - 0.00084 19.1 0.0 0.0017 18.1 0.1 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family AAA_18 PF13238.1 CCD24176.1 - 7.2e-09 36.0 0.1 1.5e-08 35.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CCD24176.1 - 7.5e-08 32.1 0.0 9.9e-08 31.7 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CCD24176.1 - 1.7e-06 28.0 0.0 2.1e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCD24176.1 - 5.8e-06 27.1 0.1 7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 CCD24176.1 - 8.4e-06 25.7 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase Zeta_toxin PF06414.7 CCD24176.1 - 0.00041 19.5 0.0 0.00056 19.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 CCD24176.1 - 0.00054 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain ABC_tran PF00005.22 CCD24176.1 - 0.0019 18.5 0.0 0.0023 18.2 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 CCD24176.1 - 0.0029 17.6 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain CPT PF07931.7 CCD24176.1 - 0.003 17.2 0.0 0.0048 16.5 0.0 1.4 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein T2SE PF00437.15 CCD24176.1 - 0.0034 16.3 0.1 0.0073 15.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 CCD24176.1 - 0.0078 15.8 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCD24176.1 - 0.0096 16.0 0.0 0.016 15.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CCD24176.1 - 0.012 15.1 0.3 0.022 14.2 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.10 CCD24176.1 - 0.017 14.9 0.3 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Guanylate_kin PF00625.16 CCD24176.1 - 0.019 14.3 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase DUF258 PF03193.11 CCD24176.1 - 0.024 13.8 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 CCD24176.1 - 0.031 13.1 0.0 0.056 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_14 PF13173.1 CCD24176.1 - 0.039 13.8 0.4 0.18 11.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 CCD24176.1 - 0.049 13.8 0.0 0.11 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 CCD24176.1 - 0.091 11.6 0.1 0.45 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PhoH PF02562.11 CCD24176.1 - 0.13 11.4 0.2 0.23 10.6 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 CCD24176.1 - 0.22 11.8 1.3 0.36 11.1 0.9 1.5 1 1 0 1 1 1 0 AAA domain FWWh PF14922.1 CCD24177.1 - 0.001 18.6 0.1 0.0033 16.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function F-box-like PF12937.2 CCD24177.1 - 0.74 9.5 0.0 0.74 9.5 0.0 2.6 4 0 0 4 4 4 0 F-box-like ApbA_C PF08546.6 CCD24178.1 - 2.5e-05 24.2 0.0 4.2e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAC PF01849.13 CCD24179.1 - 2e-16 59.2 0.1 3.8e-16 58.3 0.1 1.5 1 0 0 1 1 1 1 NAC domain Ribosomal_60s PF00428.14 CCD24179.1 - 0.028 14.8 0.4 0.13 12.6 0.0 2.0 1 1 1 2 2 2 0 60s Acidic ribosomal protein NOGCT PF08155.6 CCD24179.1 - 0.14 11.8 0.1 0.38 10.4 0.0 1.7 2 0 0 2 2 2 0 NOGCT (NUC087) domain zf-C2H2_4 PF13894.1 CCD24180.1 - 5.5e-10 38.8 4.2 0.00033 20.7 0.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCD24180.1 - 4.3e-09 36.1 9.4 0.00018 21.6 1.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCD24180.1 - 9.8e-05 22.3 4.7 0.075 13.1 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCD24180.1 - 0.013 15.3 4.0 0.29 11.1 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD24180.1 - 0.021 15.0 9.8 0.24 11.7 0.5 3.3 3 1 0 3 3 3 0 Zinc-finger double domain zf-H2C2_5 PF13909.1 CCD24180.1 - 0.022 14.9 0.8 0.022 14.9 0.6 2.6 2 1 0 2 2 2 0 C2H2-type zinc-finger domain RRN7 PF11781.3 CCD24180.1 - 0.025 14.0 0.5 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 SprA-related PF12118.3 CCD24180.1 - 0.029 13.6 2.1 0.047 13.0 1.5 1.3 1 0 0 1 1 1 0 SprA-related family RIG-I_C-RD PF11648.3 CCD24180.1 - 0.038 13.8 1.2 0.038 13.8 0.8 2.3 2 1 0 2 2 2 0 C-terminal domain of RIG-I C1_4 PF07975.7 CCD24180.1 - 0.21 11.6 3.5 0.23 11.4 0.1 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain zinc_ribbon_2 PF13240.1 CCD24180.1 - 6 6.4 6.1 2.8 7.5 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_UBOX PF13445.1 CCD24181.1 - 2.5e-15 55.9 0.7 7e-15 54.4 0.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 CCD24181.1 - 1.5e-10 40.9 1.6 1.5e-10 40.9 1.1 2.4 3 0 0 3 3 3 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_2 PF13639.1 CCD24181.1 - 0.0037 17.0 0.4 0.0073 16.1 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain CPL PF08144.6 CCD24181.1 - 0.0099 15.7 1.4 0.91 9.3 0.0 3.1 3 0 0 3 3 3 1 CPL (NUC119) domain zf-C3HC4_4 PF15227.1 CCD24181.1 - 0.057 13.2 0.2 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCD24181.1 - 0.06 13.0 0.5 0.15 11.8 0.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Med11 PF10280.4 CCD24181.1 - 0.093 12.7 10.3 0.36 10.8 5.3 2.4 2 0 0 2 2 2 0 Mediator complex protein DUF972 PF06156.8 CCD24181.1 - 3 8.2 10.8 0.99 9.7 4.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Catalase PF00199.14 CCD24182.1 - 6.7e-168 558.2 0.8 8.7e-168 557.9 0.5 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CCD24182.1 - 1.4e-12 47.2 0.1 7.1e-12 45.0 0.0 2.2 3 0 0 3 3 3 1 Catalase-related immune-responsive Sigma70_ner PF04546.8 CCD24183.1 - 2.3 7.7 16.2 4 6.9 8.3 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region Anp1 PF03452.9 CCD24184.1 - 3.1e-89 298.7 0.5 3.8e-89 298.4 0.3 1.1 1 0 0 1 1 1 1 Anp1 Staphopain_pro PF14731.1 CCD24184.1 - 0.069 12.9 3.7 4.4 7.0 0.2 2.3 2 0 0 2 2 2 0 Staphopain proregion Alk_phosphatase PF00245.15 CCD24185.1 - 2.5e-116 388.8 0.0 3e-116 388.5 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 CCD24185.1 - 3e-06 26.8 0.0 1.5e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Metalloenzyme superfamily MacB_PCD PF12704.2 CCD24185.1 - 0.031 13.8 0.8 0.55 9.7 0.1 2.5 2 1 0 2 2 2 0 MacB-like periplasmic core domain Phosphodiest PF01663.17 CCD24185.1 - 0.034 13.4 2.4 0.05 12.9 0.6 2.2 1 1 1 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase Sigma_reg_N PF13800.1 CCD24185.1 - 0.074 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal cwf21 PF08312.7 CCD24186.1 - 2.8e-10 39.8 3.9 5.5e-10 38.9 2.7 1.5 1 0 0 1 1 1 1 cwf21 domain Glyco_transf_15 PF01793.11 CCD24187.1 - 2e-138 460.8 16.4 2.8e-138 460.3 11.4 1.3 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase TPR_11 PF13414.1 CCD24188.1 - 1.5e-15 56.6 4.0 1.5e-11 43.7 1.6 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCD24188.1 - 1.5e-09 37.0 8.6 6.5e-05 22.3 0.7 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCD24188.1 - 8.4e-09 34.6 4.1 0.01 15.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCD24188.1 - 5.1e-05 23.8 0.0 0.22 12.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCD24188.1 - 0.00081 19.2 0.5 1.4 8.9 0.1 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCD24188.1 - 0.0011 18.9 0.2 0.0073 16.4 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCD24188.1 - 0.0022 18.2 0.0 0.016 15.5 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CCD24188.1 - 0.0039 17.2 3.4 0.014 15.4 1.9 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 CCD24188.1 - 0.008 16.0 0.9 0.6 10.0 0.0 3.1 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat RAMPs PF03787.10 CCD24188.1 - 1.3 8.8 4.5 2.3 8.0 3.1 1.5 1 1 0 1 1 1 0 RAMP superfamily INCENP_ARK-bind PF03941.10 CCD24189.1 - 1.8e-19 69.3 0.3 5e-19 67.9 0.2 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region ODAM PF15424.1 CCD24190.1 - 0.024 14.1 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Odontogenic ameloblast-associated family DUF371 PF04027.8 CCD24190.1 - 0.074 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF371) LRR_6 PF13516.1 CCD24191.1 - 0.025 14.6 0.0 0.025 14.6 0.0 6.0 7 0 0 7 7 7 0 Leucine Rich repeat LRR_7 PF13504.1 CCD24191.1 - 0.041 14.0 4.8 25 5.6 0.1 5.0 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 CCD24191.1 - 1.1 9.5 15.1 2 8.7 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat adh_short PF00106.20 CCD24192.1 - 3.9e-20 72.4 0.0 5.2e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCD24192.1 - 1.9e-08 34.4 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCD24192.1 - 4.5e-06 26.4 0.0 7.2e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CCD24192.1 - 0.01 14.7 0.3 0.015 14.2 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 CCD24192.1 - 0.034 14.1 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Pkinase PF00069.20 CCD24193.1 - 3.9e-74 249.0 0.0 4.5e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24193.1 - 4.2e-33 114.5 0.0 5.3e-33 114.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD24193.1 - 2.2e-05 23.5 0.0 4.8e-05 22.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCD24193.1 - 0.0018 18.0 0.0 0.018 14.7 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCD24193.1 - 0.015 14.3 0.3 0.048 12.7 0.1 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CCD24193.1 - 0.043 12.6 0.0 0.067 12.0 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gly_transf_sug PF04488.10 CCD24194.1 - 9.7e-23 80.5 0.0 2.3e-22 79.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CCD24194.1 - 0.0029 16.1 2.3 0.24 9.8 0.1 2.4 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain DUF2401 PF10287.4 CCD24195.1 - 1.3e-94 316.0 1.9 1.3e-94 316.0 1.3 1.8 2 1 1 3 3 3 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CCD24195.1 - 1.4e-31 108.4 0.3 5.7e-31 106.4 0.2 2.1 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) Macoilin PF09726.4 CCD24195.1 - 4.6 5.3 8.7 6.5 4.9 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein RAMP4 PF06624.7 CCD24196.1 - 5.7e-07 28.9 0.1 7.1e-07 28.6 0.1 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 UPF0233 PF06781.7 CCD24196.1 - 0.028 14.0 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0233) Exo5 PF09810.4 CCD24197.1 - 1.3e-32 113.3 0.0 1.2e-30 106.9 0.0 2.3 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 CCD24197.1 - 3.3e-06 26.6 0.0 8.5e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.12 CCD24197.1 - 0.00029 20.7 1.7 0.3 10.9 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function DUF83 Glutaredoxin PF00462.19 CCD24198.1 - 1.6e-15 56.7 0.0 2.6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Amidase PF01425.16 CCD24199.1 - 3.4e-93 312.9 0.0 5e-93 312.3 0.0 1.2 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 CCD24199.1 - 4.1e-84 282.0 0.0 1.4e-83 280.2 0.0 1.9 2 0 0 2 2 2 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 CCD24199.1 - 7.1e-64 214.9 0.0 1.3e-63 214.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 CCD24199.1 - 7.2e-45 152.9 0.0 1.4e-44 151.9 0.0 1.5 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 CCD24199.1 - 2.6e-37 127.3 0.0 9.6e-37 125.4 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCD24199.1 - 2.7e-32 110.9 0.0 7.6e-32 109.4 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CCD24199.1 - 1.2e-17 64.2 0.0 2.6e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CCD24199.1 - 2.7e-15 55.7 0.1 1e-14 53.9 0.1 2.0 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CCD24199.1 - 1.5e-13 50.1 0.0 4.2e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 CCD24199.1 - 2.2e-12 46.8 0.0 5.4e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CCD24199.1 - 4.7e-07 29.3 0.0 9.1e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CCD24199.1 - 2.5e-05 24.1 0.0 4.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CCD24199.1 - 0.001 18.5 0.0 0.025 14.0 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.1 CCD24199.1 - 0.11 11.6 0.0 0.25 10.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain FTR1 PF03239.9 CCD24200.1 - 2.3e-100 335.4 3.7 2.7e-100 335.2 2.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4229 PF14012.1 CCD24200.1 - 0.32 10.9 0.1 0.32 10.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) Glyco_transf_15 PF01793.11 CCD24201.1 - 3.1e-132 440.5 13.1 4.4e-132 440.0 9.1 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Abhydrolase_6 PF12697.2 CCD24202.1 - 1e-26 94.2 0.0 1.2e-26 93.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCD24202.1 - 1.8e-14 53.7 0.0 3.4e-14 52.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD24202.1 - 5e-14 52.4 0.0 8.2e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 CCD24202.1 - 7e-09 35.4 0.0 1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 CCD24202.1 - 6.7e-05 22.5 0.0 0.00038 20.1 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_2 PF02230.11 CCD24202.1 - 0.00092 18.7 0.0 0.0073 15.7 0.0 2.4 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Esterase PF00756.15 CCD24202.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.8 CCD24202.1 - 0.0023 17.5 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Hydrolase_4 PF12146.3 CCD24202.1 - 0.0054 16.5 0.0 0.016 15.0 0.0 1.9 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 CCD24202.1 - 0.0067 16.6 0.0 0.011 15.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 CCD24202.1 - 0.05 13.2 0.0 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) LCAT PF02450.10 CCD24202.1 - 0.12 11.3 0.2 0.24 10.3 0.0 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase F-box-like PF12937.2 CCD24203.1 - 9.6e-05 22.0 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCD24203.1 - 0.024 14.2 0.0 0.066 12.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain MCM PF00493.18 CCD24204.1 - 4.8e-133 443.0 0.1 2.2e-132 440.8 0.0 1.9 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 CCD24204.1 - 2.8e-26 92.3 1.0 1.3e-25 90.2 0.7 2.2 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCD24204.1 - 1.5e-07 30.7 0.0 1.7e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCD24204.1 - 8.9e-07 28.7 0.0 1.2e-05 25.0 0.0 2.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 CCD24204.1 - 9.8e-05 22.6 0.4 0.00033 21.0 0.1 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCD24204.1 - 0.055 12.9 0.0 0.74 9.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 CCD24204.1 - 0.078 12.5 0.0 0.26 10.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DER1 PF04511.10 CCD24205.1 - 1.1e-39 135.9 15.4 1.2e-39 135.8 10.7 1.0 1 0 0 1 1 1 1 Der1-like family Antimicrobial12 PF08107.6 CCD24205.1 - 0.034 13.6 0.4 0.071 12.6 0.3 1.4 1 0 0 1 1 1 0 Pleurocidin family SH3_1 PF00018.23 CCD24206.1 - 4.8e-25 86.6 0.0 8.3e-14 50.7 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 CCD24206.1 - 1.5e-15 56.4 0.7 5.2e-12 45.1 0.0 2.8 3 0 0 3 3 3 2 Variant SH3 domain PX PF00787.19 CCD24206.1 - 6e-15 55.0 0.0 2e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 PX domain SH3_2 PF07653.12 CCD24206.1 - 1.6e-10 40.2 0.0 1.7e-09 37.0 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain PB1 PF00564.19 CCD24206.1 - 4e-08 32.8 0.2 8.4e-08 31.7 0.2 1.6 1 0 0 1 1 1 1 PB1 domain Glyco_transf_15 PF01793.11 CCD24207.1 - 3.9e-120 400.7 12.3 5.1e-120 400.3 8.6 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.27 CCD24208.1 - 9.1e-59 193.3 20.5 8.1e-12 44.5 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CCD24208.1 - 3.6e-47 160.0 2.4 7e-47 159.0 1.6 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit Nup160 PF11715.3 CCD24208.1 - 7e-07 27.7 1.5 0.031 12.4 0.0 3.9 2 2 1 3 3 3 3 Nucleoporin Nup120/160 LisH PF08513.6 CCD24208.1 - 1.3e-05 24.7 1.6 1.4e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 LisH Cytochrom_D1 PF02239.11 CCD24208.1 - 0.025 12.9 0.2 0.18 10.1 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain PGI PF00342.14 CCD24209.1 - 7.9e-228 756.7 4.2 9.3e-228 756.4 2.9 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase SAP30_Sin3_bdg PF13867.1 CCD24209.1 - 0.12 12.2 0.4 32 4.5 0.1 3.1 3 0 0 3 3 3 0 Sin3 binding region of histone deacetylase complex subunit SAP30 WD40 PF00400.27 CCD24210.1 - 1.2e-22 78.9 4.8 6.3e-05 22.7 0.1 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCD24210.1 - 6.3e-18 64.4 0.7 1.3e-17 63.4 0.5 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 CCD24210.1 - 8.6e-09 35.3 3.7 8.7e-06 25.5 0.1 3.6 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A SdiA-regulated PF06977.6 CCD24210.1 - 0.065 12.1 0.0 3.1 6.6 0.0 2.4 1 1 1 2 2 2 0 SdiA-regulated NpwBP PF12622.2 CCD24211.1 - 1.9e-09 37.8 0.6 1.9e-09 37.8 0.4 1.4 2 0 0 2 2 2 1 mRNA biogenesis factor Med8 PF10232.4 CCD24212.1 - 2.7e-46 157.9 3.3 2.9e-46 157.8 2.3 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 NPV_P10 PF05531.7 CCD24212.1 - 0.0055 16.9 3.8 0.74 10.1 0.1 3.3 2 2 1 3 3 3 2 Nucleopolyhedrovirus P10 protein GxGYxYP PF14323.1 CCD24212.1 - 0.012 14.3 0.2 0.015 14.0 0.2 1.1 1 0 0 1 1 1 0 GxGYxY sequence motif in domain of unknown function TFR_dimer PF04253.10 CCD24212.1 - 0.11 12.0 1.3 2.7 7.5 0.1 2.6 2 1 1 3 3 3 0 Transferrin receptor-like dimerisation domain MbeB_N PF04837.7 CCD24212.1 - 0.19 11.8 0.9 5.1 7.2 0.2 2.6 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Mito_carr PF00153.22 CCD24213.1 - 1.3e-77 255.5 4.1 4.6e-29 99.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.11 CCD24213.1 - 0.13 12.2 0.0 2.9 7.8 0.0 2.7 3 0 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Ribosomal_L21e PF01157.13 CCD24214.1 - 2e-40 136.6 4.3 1.4e-39 133.8 2.2 2.0 1 1 1 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.4 CCD24214.1 - 0.00018 20.9 0.1 0.00022 20.6 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Ribosomal_S4 PF00163.14 CCD24215.1 - 8.6e-27 93.3 1.6 1.4e-26 92.6 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCD24215.1 - 4.6e-14 51.5 0.2 1.7e-13 49.7 0.1 2.0 1 0 0 1 1 1 1 S4 domain cwf18 PF08315.7 CCD24216.1 - 0.21 12.0 16.3 0.64 10.4 11.3 1.9 1 1 0 1 1 1 0 cwf18 pre-mRNA splicing factor YycI PF09648.5 CCD24216.1 - 0.44 9.9 4.4 0.19 11.1 1.5 1.5 1 1 0 1 1 1 0 YycH protein V_ATPase_I PF01496.14 CCD24216.1 - 1.9 6.2 6.5 2.1 6.0 4.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0016 PF01169.14 CCD24217.1 - 5.2e-40 135.4 19.3 4.4e-22 78.0 2.6 2.3 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Rick_17kDa_Anti PF05433.10 CCD24217.1 - 0.18 11.5 3.8 0.17 11.5 1.0 2.1 3 0 0 3 3 3 0 Glycine zipper 2TM domain TauE PF01925.14 CCD24217.1 - 1.2 8.5 16.3 0.25 10.7 3.0 2.2 2 0 0 2 2 2 0 Sulfite exporter TauE/SafE DUF4234 PF14018.1 CCD24217.1 - 1.3 8.8 6.5 49 3.7 4.5 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) tRNA_int_end_N2 PF12928.2 CCD24218.1 - 3.6e-17 61.5 0.0 7.8e-17 60.5 0.0 1.5 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term BRO1 PF03097.13 CCD24219.1 - 2.9e-93 312.6 8.3 2.9e-93 312.6 5.7 2.1 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CCD24219.1 - 1.7e-38 132.3 15.2 3.7e-38 131.1 10.6 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Glyoxalase_2 PF12681.2 CCD24219.1 - 0.069 13.7 0.0 0.2 12.3 0.0 1.8 1 0 0 1 1 1 0 Glyoxalase-like domain MBA1 PF07961.6 CCD24220.1 - 2.1e-92 308.2 2.1 2.6e-92 307.9 1.5 1.0 1 0 0 1 1 1 1 MBA1-like protein Glyco_transf_20 PF00982.16 CCD24220.1 - 0.025 13.0 0.2 0.036 12.5 0.1 1.3 1 1 0 1 1 1 0 Glycosyltransferase family 20 Tim44 PF04280.10 CCD24220.1 - 0.13 12.1 0.1 0.25 11.3 0.1 1.5 1 1 0 1 1 1 0 Tim44-like domain Ribosomal_L19 PF01245.15 CCD24221.1 - 0.012 15.3 0.4 0.03 14.1 0.2 1.7 1 0 0 1 1 1 0 Ribosomal protein L19 Radical_SAM PF04055.16 CCD24222.1 - 1.7e-15 57.5 0.2 5e-15 56.0 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CCD24222.1 - 1.8e-12 47.0 0.1 6.6e-12 45.3 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCD24222.1 - 0.088 12.9 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ceramidase PF05875.7 CCD24223.1 - 2.2e-89 299.0 17.2 2.6e-89 298.8 11.9 1.0 1 0 0 1 1 1 1 Ceramidase TauE PF01925.14 CCD24223.1 - 0.0013 18.2 0.2 0.0028 17.1 0.1 1.7 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE ABC2_membrane_5 PF13346.1 CCD24223.1 - 1.6 7.9 9.7 0.29 10.3 0.6 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF2892 PF11127.3 CCD24223.1 - 2.6 7.9 5.2 1 9.2 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) SRF-TF PF00319.13 CCD24224.1 - 1.7e-21 75.1 0.0 3e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ribosomal_S6e PF01092.14 CCD24225.1 - 3.1e-25 88.2 0.1 6.1e-25 87.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Cadherin_C PF01049.12 CCD24225.1 - 0.09 12.8 0.2 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Cadherin cytoplasmic region MFS_1 PF07690.11 CCD24226.1 - 5.2e-49 166.8 48.8 1.2e-48 165.6 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCD24226.1 - 2.4e-20 72.5 5.9 2.4e-20 72.5 4.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter TauE PF01925.14 CCD24226.1 - 0.11 11.9 0.0 0.11 11.9 0.0 4.3 3 2 2 5 5 5 0 Sulfite exporter TauE/SafE NOGCT PF08155.6 CCD24227.1 - 1.2e-27 95.3 1.3 2.8e-27 94.1 0.9 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 CCD24227.1 - 1.7e-27 95.0 0.5 4.1e-27 93.8 0.4 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 CCD24227.1 - 4.3e-16 58.9 0.0 1.1e-15 57.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCD24227.1 - 8.2e-08 31.6 0.0 1.8e-07 30.5 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 CCD24227.1 - 0.0093 16.4 0.1 0.031 14.7 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 CCD24227.1 - 0.01 15.6 0.0 7.1 6.4 0.0 3.0 1 1 1 2 2 2 0 Dynamin family Dynamin_N PF00350.18 CCD24228.1 - 2e-16 60.2 0.4 2e-16 60.2 0.3 2.6 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CCD24228.1 - 7e-09 35.6 0.6 3.1e-08 33.5 0.4 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCD24228.1 - 4e-08 32.9 4.5 6.6e-07 28.9 3.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CCD24228.1 - 0.045 13.2 0.1 8.1 5.9 0.1 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 CCD24228.1 - 0.06 14.1 0.5 2.5 8.9 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_18 PF13238.1 CCD24228.1 - 0.25 11.6 0.0 0.25 11.6 0.0 3.1 4 0 0 4 4 4 0 AAA domain DUF2935 PF11155.3 CCD24228.1 - 2 8.5 7.1 17 5.4 0.3 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Hexapep PF00132.19 CCD24229.1 - 3.5e-16 57.8 13.9 2.5e-10 39.4 1.5 3.2 2 1 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CCD24229.1 - 3.8e-15 55.1 13.9 2e-10 40.0 0.3 2.8 3 1 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Abhydrolase_1 PF00561.15 CCD24230.1 - 4.6e-26 91.7 0.0 6.9e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCD24230.1 - 2.7e-13 50.3 0.0 4e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCD24230.1 - 8.7e-10 38.5 0.0 3.9e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 CCD24230.1 - 0.00072 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Cutinase DUF3188 PF11384.3 CCD24231.1 - 0.1 12.1 0.6 0.69 9.5 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3188) CoA_binding_3 PF13727.1 CCD24231.1 - 0.16 11.7 2.4 0.18 11.6 1.7 1.0 1 0 0 1 1 1 0 CoA-binding domain tRNA-synt_1b PF00579.20 CCD24232.1 - 1.3e-74 250.9 0.0 2.1e-74 250.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Romo1 PF10247.4 CCD24233.1 - 1.7e-27 95.4 8.1 2.1e-27 95.0 5.6 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 PAXNEB PF05625.6 CCD24234.1 - 6.6e-105 350.9 0.7 8.1e-105 350.6 0.5 1.0 1 0 0 1 1 1 1 PAXNEB protein Pantoate_transf PF02548.10 CCD24235.1 - 9.3e-93 310.1 0.0 1.2e-92 309.8 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 CCD24235.1 - 5.1e-05 22.6 0.0 7.5e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase WD40 PF00400.27 CCD24236.1 - 1.4e-30 104.0 11.9 6.1e-08 32.2 0.0 6.3 7 0 0 7 7 7 4 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CCD24236.1 - 3.9e-05 22.6 0.0 0.00011 21.1 0.0 1.6 2 1 0 2 2 2 1 Coatomer WD associated region eIF2A PF08662.6 CCD24236.1 - 0.00087 19.0 0.0 0.36 10.5 0.0 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCD24236.1 - 0.0025 16.0 0.3 0.2 9.7 0.0 2.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CCD24236.1 - 0.0068 14.7 0.0 1.1 7.4 0.0 2.1 1 1 0 2 2 2 2 Cytochrome D1 heme domain Hira PF07569.6 CCD24236.1 - 0.021 14.0 1.1 1.7 7.8 0.1 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split PD40 PF07676.7 CCD24236.1 - 0.044 13.4 0.0 9.7 5.9 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat UMP1 PF05348.6 CCD24237.1 - 3e-35 121.0 0.1 3.4e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 GYF PF02213.11 CCD24238.1 - 1.7e-19 69.1 0.1 4.1e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 GYF domain Sec66 PF09802.4 CCD24239.1 - 1.2e-71 240.1 2.9 1.4e-71 239.8 2.0 1.1 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 60KD_IMP PF02096.15 CCD24239.1 - 0.015 14.9 0.2 0.31 10.6 0.1 2.1 2 0 0 2 2 2 0 60Kd inner membrane protein Aha1_N PF09229.6 CCD24239.1 - 0.03 14.1 0.3 0.087 12.6 0.0 1.8 2 0 0 2 2 2 0 Activator of Hsp90 ATPase, N-terminal Tubulin_3 PF14881.1 CCD24239.1 - 0.033 13.6 0.2 1 8.7 0.0 2.3 1 1 0 2 2 2 0 Tubulin domain DUF3015 PF11220.3 CCD24239.1 - 0.12 11.9 2.8 10 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3015) NPL4 PF05021.10 CCD24240.1 - 1.4e-126 421.7 0.1 1.8e-126 421.4 0.1 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CCD24240.1 - 6.1e-73 243.3 2.1 1e-72 242.6 1.5 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 CCD24240.1 - 0.0025 18.0 0.0 0.016 15.4 0.0 2.4 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 RHH_1 PF01402.16 CCD24240.1 - 0.15 12.0 0.1 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HSP70 PF00012.15 CCD24241.1 - 1.5e-174 581.3 9.6 1.5e-174 581.3 6.6 1.9 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CCD24241.1 - 4.5e-07 28.7 0.1 8.5e-07 27.8 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 CCD24241.1 - 0.00024 20.9 5.6 0.048 13.5 0.1 4.2 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.11 CCD24241.1 - 0.2 11.2 0.3 0.56 9.8 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain Pex24p PF06398.6 CCD24242.1 - 6.7e-34 117.2 23.0 8.7e-34 116.8 15.9 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rpp20 PF12328.3 CCD24243.1 - 4.4e-27 94.4 10.6 2.6e-19 69.2 3.0 2.1 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 CCD24243.1 - 2.7e-16 58.8 0.5 4.5e-16 58.2 0.4 1.3 1 0 0 1 1 1 1 Alba MSC PF09402.5 CCD24243.1 - 0.0097 14.6 1.0 0.011 14.4 0.7 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain PNPase PF03726.9 CCD24243.1 - 0.02 15.1 2.4 0.038 14.2 1.1 1.9 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain PDH PF02153.12 CCD24244.1 - 1.6e-07 30.5 0.2 2.3e-07 29.9 0.1 1.4 1 1 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 CCD24244.1 - 2.5e-05 24.6 0.0 5.7e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CCD24244.1 - 0.00011 21.7 0.0 0.00027 20.4 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 CCD24244.1 - 0.00013 21.8 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 CCD24244.1 - 0.0026 16.9 0.0 0.0046 16.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CCD24244.1 - 0.0092 15.6 0.0 0.016 14.8 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CCD24244.1 - 0.036 13.4 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 CCD24244.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain EBV-NA3 PF05009.7 CCD24245.1 - 0.066 12.4 0.7 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Kinetocho_Slk19 PF12709.2 CCD24247.1 - 6.9e-30 102.9 15.1 6.9e-30 102.9 10.5 10.9 3 2 6 11 11 11 1 Central kinetochore-associated Reo_sigmaC PF04582.7 CCD24247.1 - 0.0017 17.6 4.7 0.0017 17.6 3.2 4.3 2 1 3 5 5 5 3 Reovirus sigma C capsid protein IncA PF04156.9 CCD24247.1 - 0.0066 16.0 26.6 0.0066 16.0 18.4 6.1 2 1 3 5 5 5 3 IncA protein DUF972 PF06156.8 CCD24247.1 - 0.016 15.5 9.3 0.016 15.5 6.4 10.6 2 2 9 12 12 12 0 Protein of unknown function (DUF972) T2SF PF00482.18 CCD24247.1 - 3 7.7 5.4 5.8 6.8 0.1 3.3 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Asp_protease PF09668.5 CCD24248.1 - 5.5e-51 171.3 0.0 8.5e-51 170.6 0.0 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 CCD24248.1 - 3.8e-10 40.1 0.4 1.6e-09 38.0 0.1 2.1 2 0 0 2 2 2 1 Aspartyl protease UBA PF00627.26 CCD24248.1 - 2.4e-08 33.5 0.1 2.5e-07 30.3 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain RVP_2 PF08284.6 CCD24248.1 - 5e-06 26.4 0.0 2.3e-05 24.3 0.0 2.1 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CCD24248.1 - 1.2e-05 24.9 0.0 2.9e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 CCD24248.1 - 5.9e-05 22.9 0.1 0.00021 21.1 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease UN_NPL4 PF11543.3 CCD24248.1 - 0.019 15.2 0.0 0.042 14.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 UCH PF00443.24 CCD24249.1 - 4.9e-62 209.4 1.7 1.1e-61 208.2 1.2 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCD24249.1 - 1.7e-23 83.5 1.9 1.7e-23 83.5 1.3 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 CCD24249.1 - 8.5e-06 26.0 0.0 4.4e-05 23.8 0.0 2.3 3 0 0 3 3 3 1 Rhodanese-like domain Zn-ribbon_8 PF09723.5 CCD24249.1 - 0.62 10.0 5.4 2 8.4 2.5 2.4 2 0 0 2 2 2 0 Zinc ribbon domain FTR1 PF03239.9 CCD24250.1 - 3.2e-98 328.4 6.4 3.8e-98 328.2 4.5 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family adh_short PF00106.20 CCD24251.1 - 9.4e-17 61.4 0.0 1.5e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCD24251.1 - 8.5e-10 38.5 0.1 2.2e-09 37.2 0.0 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 CCD24251.1 - 7.4e-05 22.2 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCD24251.1 - 0.013 15.5 0.0 0.046 13.7 0.0 1.9 1 1 0 1 1 1 0 NADH(P)-binding adh_short_C2 PF13561.1 CCD24251.1 - 0.019 14.7 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Metallophos PF00149.23 CCD24253.1 - 5.5e-41 140.1 0.2 6.8e-41 139.8 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCD24253.1 - 0.00021 21.1 0.0 0.0003 20.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain UCH PF00443.24 CCD24254.1 - 3.3e-54 183.8 0.4 3.3e-54 183.8 0.3 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Aminotran_1_2 PF00155.16 CCD24255.1 - 7.2e-16 58.0 0.0 3.8e-15 55.7 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CCD24255.1 - 0.0017 17.0 0.0 0.0037 15.8 0.0 1.4 2 0 0 2 2 2 1 Alanine-glyoxylate amino-transferase PET122 PF05476.6 CCD24256.1 - 4.6e-81 271.9 1.1 5.8e-81 271.6 0.8 1.0 1 0 0 1 1 1 1 PET122 60KD_IMP PF02096.15 CCD24257.1 - 4.8e-38 130.8 2.2 4.8e-38 130.8 1.6 2.1 2 0 0 2 2 2 1 60Kd inner membrane protein RhoGAP PF00620.22 CCD24258.1 - 1.3e-37 128.7 0.1 5.5e-37 126.7 0.1 2.2 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 CCD24258.1 - 1.7e-17 63.7 7.0 1.9e-17 63.5 0.5 3.5 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 CCD24258.1 - 2e-15 56.7 0.5 2e-15 56.7 0.3 4.8 4 0 0 4 4 4 1 RasGEF N-terminal motif UPF0160 PF03690.8 CCD24259.1 - 2.7e-122 408.1 0.0 3.1e-122 407.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Gallidermin PF02052.10 CCD24259.1 - 0.006 16.6 0.0 0.026 14.6 0.0 2.0 2 0 0 2 2 2 1 Gallidermin Sec34 PF04136.10 CCD24260.1 - 2.7e-22 79.1 11.9 2.7e-22 79.1 8.3 3.3 3 0 0 3 3 3 1 Sec34-like family CBFD_NFYB_HMF PF00808.18 CCD24263.1 - 1.7e-12 47.2 0.0 3.1e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCD24263.1 - 0.0046 17.0 0.0 0.0098 15.9 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Ribosomal_60s PF00428.14 CCD24263.1 - 0.55 10.6 7.8 0.027 14.8 1.5 1.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein SPT2 PF08243.6 CCD24264.1 - 0.0044 17.3 8.7 0.0044 17.3 6.0 2.5 2 1 0 2 2 2 1 SPT2 chromatin protein PBP1_TM PF14812.1 CCD24264.1 - 0.04 14.2 11.4 0.04 14.2 7.9 3.1 3 1 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Rad4 PF03835.10 CCD24265.1 - 2.1e-32 111.5 5.1 6.3e-32 109.9 3.6 1.9 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 CCD24265.1 - 2.5e-27 94.3 0.3 4.7e-27 93.5 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 CCD24265.1 - 7.2e-18 63.8 0.1 4.5e-17 61.3 0.0 2.2 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CCD24265.1 - 2.6e-08 34.0 3.1 4.7e-08 33.2 0.0 2.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CCD24265.1 - 0.00033 20.8 0.5 0.0016 18.6 0.0 2.3 3 0 0 3 3 3 1 Transglutaminase-like superfamily ChaC PF04752.7 CCD24266.1 - 1.4e-59 201.0 0.0 1.8e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Copper-fist PF00649.13 CCD24267.1 - 1.7e-20 71.9 4.7 4.1e-20 70.7 3.2 1.7 1 0 0 1 1 1 1 Copper fist DNA binding domain SNF2_N PF00176.18 CCD24268.1 - 4.3e-75 252.2 0.2 9.9e-75 251.0 0.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 CCD24268.1 - 3.1e-29 101.1 2.7 3.1e-29 101.1 1.9 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Chromo PF00385.19 CCD24268.1 - 1e-24 85.9 1.5 1.1e-14 53.8 0.1 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CCD24268.1 - 2e-15 56.4 0.0 1.2e-14 53.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 CCD24268.1 - 0.034 14.2 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain RRM_1 PF00076.17 CCD24269.1 - 4.5e-86 282.4 8.7 1.7e-21 75.5 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD24269.1 - 4.4e-61 202.7 0.5 2.4e-16 59.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD24269.1 - 1.9e-44 149.2 0.2 6e-11 42.0 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CCD24269.1 - 1.4e-21 75.9 0.4 2e-20 72.2 0.0 2.7 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CCD24269.1 - 2.5e-06 27.2 12.4 0.62 9.9 0.0 5.1 4 1 1 5 5 5 3 RNA binding motif TC1 PF15063.1 CCD24269.1 - 0.0034 16.8 0.1 0.019 14.4 0.0 2.3 2 0 0 2 2 2 1 Thyroid cancer protein 1 Nup35_RRM_2 PF14605.1 CCD24269.1 - 0.0072 16.0 0.1 9 6.1 0.0 3.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif ACT PF01842.20 CCD24269.1 - 0.01 15.3 0.0 8.4 5.9 0.0 3.4 3 0 0 3 3 3 1 ACT domain CbiG_mid PF11761.3 CCD24269.1 - 0.018 15.2 0.1 3.3 8.0 0.0 2.8 2 0 0 2 2 2 0 Cobalamin biosynthesis central region YflT PF11181.3 CCD24269.1 - 0.07 13.2 8.2 1.5 8.9 0.8 3.5 2 1 1 3 3 3 0 Heat induced stress protein YflT OB_RNB PF08206.6 CCD24269.1 - 0.091 12.2 5.9 7.3 6.1 0.2 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain E1-E2_ATPase PF00122.15 CCD24270.1 - 7.4e-16 57.8 1.7 8.4e-16 57.7 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CCD24270.1 - 1.3e-12 48.2 0.0 3.4e-12 46.9 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCD24270.1 - 1.7e-12 47.0 0.0 4.4e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 CCD24270.1 - 2.9e-09 37.6 0.1 1.6e-07 31.9 0.0 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCD24270.1 - 0.0032 17.0 0.2 0.007 15.9 0.2 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF281 PF03436.8 CCD24270.1 - 0.061 13.3 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF281) DUF4131 PF13567.1 CCD24270.1 - 1.4 8.3 6.7 40 3.5 4.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) NESP55 PF06390.7 CCD24271.1 - 0.37 10.1 8.4 0.019 14.3 1.8 1.8 2 0 0 2 2 2 0 Neuroendocrine-specific golgi protein P55 (NESP55) Rad21_Rec8_N PF04825.8 CCD24272.1 - 7.7e-17 61.2 0.7 3.3e-16 59.2 0.5 2.1 1 1 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CCD24272.1 - 0.062 12.4 0.0 0.17 11.0 0.0 1.8 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein ICL PF00463.16 CCD24273.1 - 3e-162 540.5 0.0 3.4e-162 540.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CCD24273.1 - 7.6e-08 31.8 0.0 1.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Clat_adaptor_s PF01217.15 CCD24274.1 - 3e-11 43.2 0.1 9.7e-11 41.5 0.1 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Bromo_TP PF07524.8 CCD24275.1 - 4.6e-06 26.2 0.0 1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated NUC173 PF08161.7 CCD24276.1 - 4.8e-74 248.0 0.1 1.4e-71 239.9 0.2 2.9 2 0 0 2 2 2 2 NUC173 domain HEAT PF02985.17 CCD24276.1 - 1.9e-06 27.4 0.2 0.18 11.9 0.0 5.7 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 CCD24276.1 - 0.0016 18.7 2.0 0.58 10.4 0.1 4.7 5 1 1 6 6 6 1 HEAT repeats HEAT_EZ PF13513.1 CCD24276.1 - 0.0024 18.3 0.0 2.7 8.5 0.0 4.2 5 0 0 5 5 5 1 HEAT-like repeat Inh PF02974.9 CCD24276.1 - 0.052 13.1 0.0 0.38 10.3 0.0 2.4 2 0 0 2 2 2 0 Protease inhibitor Inh Ribosomal_S16 PF00886.14 CCD24277.1 - 1e-24 85.9 0.1 1.4e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 DUF3292 PF11696.3 CCD24278.1 - 0.067 11.0 2.4 0.13 10.1 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DEAD_2 PF06733.10 CCD24279.1 - 8.9e-50 168.4 0.0 1.9e-49 167.4 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CCD24279.1 - 1.6e-46 158.3 0.0 3.1e-46 157.3 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 CCD24279.1 - 0.00016 21.2 0.0 0.059 12.8 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CCD24279.1 - 0.0013 18.5 3.8 0.22 11.3 0.1 3.3 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit MitMem_reg PF13012.1 CCD24279.1 - 0.002 18.2 0.7 0.0097 15.9 0.5 2.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function PhoH PF02562.11 CCD24279.1 - 0.0042 16.3 0.3 0.44 9.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 CCD24279.1 - 0.01 15.9 0.2 3.5 7.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF4611 PF15387.1 CCD24279.1 - 0.093 12.8 1.2 0.5 10.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Chol_subst-bind PF09129.6 CCD24279.1 - 0.16 11.0 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Cholesterol oxidase, substrate-binding AAA_30 PF13604.1 CCD24279.1 - 0.22 11.0 0.0 0.5 9.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-TFIIIC PF12660.2 CCD24280.1 - 3.1e-11 43.0 0.0 5.9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex Patched PF02460.13 CCD24281.1 - 2.2e-50 171.4 28.9 2.2e-28 98.7 5.1 3.4 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 CCD24281.1 - 1.6e-35 121.8 6.3 1.6e-35 121.8 4.4 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.10 CCD24281.1 - 0.0044 15.7 1.3 0.0044 15.7 0.9 2.2 2 0 0 2 2 2 2 MMPL family ACR_tran PF00873.14 CCD24281.1 - 0.022 12.1 26.6 0.036 11.5 13.6 2.8 3 0 0 3 3 3 0 AcrB/AcrD/AcrF family Mpv17_PMP22 PF04117.7 CCD24282.1 - 1.7e-28 98.0 4.8 2.9e-28 97.3 3.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family PPR_2 PF13041.1 CCD24283.1 - 0.0012 18.7 3.0 0.052 13.5 0.0 3.4 3 0 0 3 3 3 2 PPR repeat family CagY_M PF07337.6 CCD24283.1 - 0.037 13.4 0.4 0.13 11.8 0.0 2.1 2 0 0 2 2 2 0 DC-EC Repeat Pil1 PF13805.1 CCD24284.1 - 2.5e-149 495.7 0.8 3e-149 495.5 0.5 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.5 CCD24284.1 - 0.022 14.5 2.3 0.14 12.0 0.1 2.7 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit zf-C2H2 PF00096.21 CCD24285.1 - 3.9e-07 30.0 14.8 9.3e-05 22.5 1.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD24285.1 - 6e-05 23.0 8.9 0.0013 18.9 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD24285.1 - 0.00023 21.2 0.2 0.00023 21.2 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-BED PF02892.10 CCD24285.1 - 2.3 8.0 9.6 0.15 11.8 0.6 2.7 2 0 0 2 2 2 0 BED zinc finger Peptidase_C48 PF02902.14 CCD24286.1 - 2.9e-40 138.2 1.3 2.9e-40 138.2 0.9 2.2 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain SIR2 PF02146.12 CCD24287.1 - 4.6e-53 179.5 0.0 7.2e-53 178.9 0.0 1.3 1 0 0 1 1 1 1 Sir2 family HSDR_N PF04313.9 CCD24287.1 - 0.25 11.0 2.3 0.39 10.4 1.6 1.2 1 0 0 1 1 1 0 Type I restriction enzyme R protein N terminus (HSDR_N) FYVE_2 PF02318.11 CCD24287.1 - 2.7 7.9 4.9 1.7 8.5 0.1 2.4 2 1 0 2 2 2 0 FYVE-type zinc finger MoeZ_MoeB PF05237.8 CCD24288.1 - 0.097 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 MoeZ/MoeB domain DEAD PF00270.24 CCD24289.1 - 3.5e-40 137.2 0.1 9.2e-40 135.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD24289.1 - 7.3e-21 73.8 0.0 3.7e-20 71.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCD24289.1 - 8.9e-16 57.1 0.2 1.9e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CCD24289.1 - 3.3e-05 23.7 0.0 3.3e-05 23.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2207 PF09972.4 CCD24290.1 - 0.01 14.4 0.4 0.013 14.1 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SUR7 PF06687.7 CCD24290.1 - 0.032 13.8 0.3 0.051 13.1 0.2 1.3 1 0 0 1 1 1 0 SUR7/PalI family HlyIII PF03006.15 CCD24290.1 - 0.078 12.3 6.0 0.14 11.5 4.2 1.4 1 1 0 1 1 1 0 Haemolysin-III related bZIP_C PF12498.3 CCD24294.1 - 0.36 12.0 6.6 0.29 12.3 3.3 1.8 1 1 0 1 1 1 0 Basic leucine-zipper C terminal DUF2781 PF10914.3 CCD24295.1 - 3.5e-33 114.4 5.4 4e-33 114.2 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) YwiC PF14256.1 CCD24295.1 - 0.11 12.6 1.5 0.18 11.9 0.5 1.7 2 0 0 2 2 2 0 YwiC-like protein DAO PF01266.19 CCD24296.1 - 2.1e-09 36.7 0.0 3.2e-05 23.0 0.0 2.4 2 1 1 3 3 3 2 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 CCD24296.1 - 0.033 13.5 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 CCD24296.1 - 0.067 12.6 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA SH3_6 PF12913.2 CCD24296.1 - 0.13 11.5 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 SH3 domain of the SH3b1 type WW PF00397.21 CCD24297.1 - 2.3e-07 30.5 0.9 2.3e-07 30.5 0.6 2.0 2 0 0 2 2 2 1 WW domain DUF605 PF04652.11 CCD24297.1 - 0.063 12.6 16.6 0.066 12.5 11.5 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CCD24297.1 - 0.099 10.8 20.8 0.11 10.7 14.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 THRAP3_BCLAF1 PF15440.1 CCD24297.1 - 1.7 7.1 7.1 1.9 7.0 4.9 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF2076 PF09849.4 CCD24297.1 - 3.7 7.5 36.4 1.1e+02 2.7 25.2 2.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Pyr_redox_dim PF02852.17 CCD24299.1 - 1.6e-42 143.9 0.1 4.1e-42 142.6 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CCD24299.1 - 4.2e-39 134.5 12.6 4.3e-37 127.9 8.7 3.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCD24299.1 - 1.1e-20 73.7 6.3 1.3e-17 63.9 0.6 3.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCD24299.1 - 1.6e-12 47.2 0.2 1.6e-09 37.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCD24299.1 - 6.8e-11 42.6 0.3 1.9e-06 28.0 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCD24299.1 - 1.5e-09 37.7 3.3 2.9e-05 24.0 0.6 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 CCD24299.1 - 3.8e-09 35.8 5.8 6.1e-09 35.2 0.9 2.3 1 1 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 CCD24299.1 - 1.1e-06 27.7 1.7 1.1e-06 27.7 1.2 2.7 2 1 1 3 3 3 1 FAD binding domain DAO PF01266.19 CCD24299.1 - 2.4e-06 26.6 9.4 0.0045 15.9 0.1 3.7 3 1 1 4 4 4 2 FAD dependent oxidoreductase HI0933_like PF03486.9 CCD24299.1 - 7.8e-06 24.6 11.4 0.00024 19.6 0.7 4.0 3 1 1 4 4 4 2 HI0933-like protein Thi4 PF01946.12 CCD24299.1 - 0.00012 21.2 1.0 0.002 17.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 CCD24299.1 - 0.00028 20.0 6.1 0.036 13.1 0.3 3.4 3 1 0 3 3 3 1 FAD binding domain K_oxygenase PF13434.1 CCD24299.1 - 0.0025 16.8 0.2 2.6 6.8 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 CCD24299.1 - 0.0027 17.2 0.3 0.57 9.7 0.1 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.14 CCD24299.1 - 0.017 14.1 0.2 0.065 12.3 0.1 2.0 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF4479 PF14794.1 CCD24299.1 - 0.1 12.1 3.7 14 5.2 0.1 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF4479) 3HCDH_N PF02737.13 CCD24299.1 - 0.2 11.2 5.1 0.093 12.3 0.4 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 CCD24299.1 - 7.3 5.3 5.4 1.9 7.3 0.3 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein Fcf2 PF08698.6 CCD24300.1 - 1.6e-31 108.2 1.1 1.6e-31 108.2 0.8 2.3 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing RED_C PF07807.6 CCD24300.1 - 0.047 13.8 4.6 0.13 12.4 3.2 1.8 1 0 0 1 1 1 0 RED-like protein C-terminal region WD40 PF00400.27 CCD24301.1 - 1.3e-11 43.8 0.8 0.0095 15.8 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat DUF572 PF04502.8 CCD24301.1 - 7.1 5.7 47.3 3.8 6.6 1.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) FA_hydroxylase PF04116.8 CCD24302.1 - 2.5e-11 43.9 17.9 2.5e-11 43.9 12.4 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_hydro_47 PF01532.15 CCD24304.1 - 2e-79 267.3 0.1 6.5e-79 265.6 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 RNase_T PF00929.19 CCD24305.1 - 5.5e-31 108.0 1.8 7.6e-31 107.6 0.4 1.8 2 0 0 2 2 2 1 Exonuclease DUF4148 PF13663.1 CCD24305.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4148) Ribosomal_L22e PF01776.12 CCD24306.1 - 3.1e-42 143.1 0.8 3.6e-42 142.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF3115 PF11312.3 CCD24307.1 - 8.8e-103 343.4 1.3 1e-102 343.2 0.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) DUP PF00674.13 CCD24307.1 - 0.0044 16.9 0.4 3.4 7.6 0.0 2.5 2 0 0 2 2 2 2 DUP family MecA PF05389.7 CCD24307.1 - 0.0065 16.0 0.4 0.011 15.3 0.3 1.4 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) Rsm22 PF09243.5 CCD24307.1 - 0.0091 15.0 0.0 1.3 7.9 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Tubulin PF00091.20 CCD24308.1 - 1.8e-68 230.5 0.0 3.6e-68 229.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCD24308.1 - 1.8e-47 160.4 0.3 1.2e-46 157.8 0.1 2.2 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CCD24308.1 - 0.00087 18.7 0.0 0.0021 17.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CCD24308.1 - 0.0035 17.3 0.0 0.0096 15.9 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain PRESAN PF09687.5 CCD24308.1 - 0.41 10.7 6.3 2.1 8.4 3.8 2.2 2 0 0 2 2 2 0 Plasmodium RESA N-terminal UPF0121 PF03661.8 CCD24309.1 - 0.0057 15.8 14.7 0.01 15.0 10.2 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0121) DIM PF08194.7 CCD24309.1 - 0.017 15.0 0.8 0.16 11.9 0.0 2.5 2 0 0 2 2 2 0 DIM protein DUF788 PF05620.6 CCD24310.1 - 1.1e-45 155.5 0.6 1.2e-45 155.3 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) PPR_3 PF13812.1 CCD24311.1 - 3.6e-11 42.4 0.0 3.6 8.1 0.0 8.3 11 0 0 11 11 11 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 CCD24311.1 - 4.3e-11 42.5 11.0 0.0029 17.5 0.0 6.7 6 0 0 6 6 6 4 PPR repeat family PPR PF01535.15 CCD24311.1 - 3.6e-05 23.4 14.8 1.7 8.7 0.0 7.4 9 0 0 9 9 9 3 PPR repeat TPR_14 PF13428.1 CCD24311.1 - 0.00044 20.6 1.2 16 6.4 0.0 5.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCD24311.1 - 0.0041 17.4 0.2 4 7.8 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat COX5A PF02284.11 CCD24311.1 - 0.013 15.4 0.0 4.4 7.2 0.0 3.5 1 1 2 3 3 3 0 Cytochrome c oxidase subunit Va DUF148 PF02520.12 CCD24311.1 - 0.031 14.0 3.7 0.19 11.5 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function DUF148 BUD22 PF09073.5 CCD24311.1 - 0.63 9.0 1.5 1 8.3 1.0 1.3 1 0 0 1 1 1 0 BUD22 rRNA_processing PF08524.6 CCD24312.1 - 9.7e-39 132.5 36.6 1.1e-38 132.3 25.4 1.0 1 0 0 1 1 1 1 rRNA processing PV-1 PF06637.6 CCD24312.1 - 1.2 7.6 11.4 1.3 7.5 7.9 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) GTP_EFTU PF00009.22 CCD24313.1 - 3.8e-60 202.5 0.1 6.5e-60 201.7 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCD24313.1 - 4.3e-35 119.8 0.0 8.9e-35 118.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 CCD24313.1 - 1.5e-30 104.8 0.0 3.2e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CCD24313.1 - 2.4e-23 81.8 0.0 5.1e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCD24313.1 - 1e-13 51.1 0.3 3.1e-13 49.6 0.2 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 CCD24313.1 - 0.0064 16.9 0.0 0.015 15.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Med14 PF08638.6 CCD24314.1 - 3.1e-58 196.2 6.6 3.1e-58 196.2 4.5 2.4 2 0 0 2 2 2 1 Mediator complex subunit MED14 GRAM PF02893.15 CCD24315.1 - 1.1e-06 28.0 0.4 2.4e-06 26.9 0.2 1.6 1 0 0 1 1 1 1 GRAM domain DUF912 PF06024.7 CCD24315.1 - 0.26 11.3 12.1 0.18 11.8 0.9 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) OTU PF02338.14 CCD24316.1 - 4.2e-12 46.7 0.1 8.7e-12 45.6 0.0 1.5 1 1 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_jaz PF12171.3 CCD24317.1 - 1.1e-09 38.1 5.3 1.1e-09 38.1 3.7 2.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CCD24317.1 - 7.6e-05 22.7 0.1 0.00014 21.8 0.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-AD PF07776.10 CCD24317.1 - 0.089 12.8 0.1 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) zf-C2H2_4 PF13894.1 CCD24317.1 - 0.25 11.7 3.4 0.3 11.5 1.2 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD24317.1 - 0.8 10.1 3.5 1.4 9.3 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double domain Hypoth_Ymh PF09509.5 CCD24317.1 - 1 8.9 3.8 0.44 10.1 0.9 1.8 2 1 0 2 2 2 0 Protein of unknown function (Hypoth_ymh) zf-met PF12874.2 CCD24317.1 - 1.9 8.8 4.7 1.5 9.1 2.0 1.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ribosomal_L16 PF00252.13 CCD24318.1 - 6.8e-34 116.4 0.1 8.6e-34 116.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RCC1 PF00415.13 CCD24319.1 - 2e-20 72.7 0.1 0.00012 22.2 0.1 5.5 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCD24319.1 - 1.1e-09 37.6 6.0 5.9e-06 25.7 0.0 4.1 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat V-SNARE_C PF12352.3 CCD24320.1 - 3.5e-09 36.5 2.6 3.5e-09 36.5 1.8 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CCD24320.1 - 0.00043 19.9 1.1 0.00043 19.9 0.8 2.9 2 1 1 3 3 3 1 Sec20 Orthopox_B11R PF07033.6 CCD24320.1 - 0.19 11.2 1.9 0.46 9.9 1.3 1.7 1 0 0 1 1 1 0 Orthopoxvirus B11R protein V_ATPase_I PF01496.14 CCD24320.1 - 0.75 7.5 7.5 0.69 7.6 4.6 1.3 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Snapin_Pallidin PF14712.1 CCD24320.1 - 6.9 7.0 10.2 3.2 8.1 0.1 3.5 3 1 1 4 4 4 0 Snapin/Pallidin FliD_N PF02465.13 CCD24320.1 - 8.4 6.8 15.1 6.8 7.1 1.8 2.6 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Lectin_leg-like PF03388.8 CCD24322.1 - 1e-49 168.7 0.2 1.5e-49 168.1 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Fib_alpha PF08702.5 CCD24322.1 - 0.074 13.1 0.6 0.15 12.2 0.2 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DEAD PF00270.24 CCD24323.1 - 3e-10 39.8 0.0 4e-09 36.1 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD24323.1 - 3e-08 33.4 0.0 1e-07 31.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Sir1 PF11603.3 CCD24323.1 - 0.0054 16.8 0.4 0.011 15.8 0.3 1.6 1 0 0 1 1 1 1 Regulatory protein Sir1 MFS_1 PF07690.11 CCD24325.1 - 1.1e-13 50.6 6.0 4.4e-13 48.6 4.1 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sec23_trunk PF04811.10 CCD24326.1 - 9.4e-67 224.9 0.0 1.4e-66 224.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCD24326.1 - 2.9e-31 106.9 1.4 7.7e-31 105.5 0.4 2.2 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCD24326.1 - 1.4e-26 92.7 0.2 3.3e-26 91.6 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CCD24326.1 - 7e-11 41.6 0.0 1.4e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.10 CCD24326.1 - 1.8e-09 36.9 10.0 3.4e-09 36.1 6.9 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger NBP1 PF08537.5 CCD24327.1 - 2.7e-34 118.8 35.4 5.5e-31 107.9 24.6 2.2 1 1 0 1 1 1 1 Fungal Nap binding protein NBP1 Pyridox_oxidase PF01243.15 CCD24328.1 - 4.7e-16 58.5 0.0 9.4e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PWWP PF00855.12 CCD24329.1 - 3.6e-17 62.3 0.5 1.2e-16 60.6 0.1 2.1 2 0 0 2 2 2 1 PWWP domain Ig_3 PF13927.1 CCD24329.1 - 0.1 13.1 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 Immunoglobulin domain DUF4131 PF13567.1 CCD24330.1 - 0.054 12.9 0.4 0.056 12.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3810 PF12725.2 CCD24330.1 - 0.062 12.2 0.3 0.07 12.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Tetraspannin PF00335.15 CCD24330.1 - 0.12 11.5 1.1 0.15 11.3 0.8 1.1 1 0 0 1 1 1 0 Tetraspanin family ABC2_membrane_2 PF12679.2 CCD24330.1 - 0.15 10.9 0.8 0.18 10.6 0.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2545 PF10810.3 CCD24330.1 - 0.24 11.8 2.7 1.9 8.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2545) ABC2_membrane_3 PF12698.2 CCD24330.1 - 0.8 8.6 4.1 0.95 8.4 2.8 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein ABC2_membrane_4 PF12730.2 CCD24330.1 - 4 6.5 7.3 6.8 5.7 5.1 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Med10 PF09748.4 CCD24331.1 - 9.9e-45 151.4 0.9 1.4e-44 151.0 0.4 1.3 1 1 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF4404 PF14357.1 CCD24331.1 - 0.022 15.1 4.2 9.8 6.6 0.4 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) PBS_linker_poly PF00427.16 CCD24331.1 - 0.027 14.1 0.2 0.056 13.1 0.1 1.6 1 1 0 1 1 1 0 Phycobilisome Linker polypeptide DUF342 PF03961.8 CCD24331.1 - 0.037 12.4 0.6 0.048 12.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4635 PF15466.1 CCD24331.1 - 0.064 12.5 0.5 4.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4635) BLOC1_2 PF10046.4 CCD24331.1 - 0.072 13.2 3.4 12 6.1 0.1 3.0 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Bacillus_HBL PF05791.6 CCD24331.1 - 0.1 11.9 4.8 0.21 10.9 0.3 2.4 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF2203 PF09969.4 CCD24331.1 - 0.17 12.0 1.2 4.7 7.4 0.0 2.5 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Syntaxin PF00804.20 CCD24331.1 - 0.21 11.7 7.1 0.5 10.5 1.8 2.7 2 1 0 2 2 2 0 Syntaxin RIC3 PF15361.1 CCD24331.1 - 0.27 11.4 1.5 2.5 8.3 0.1 2.1 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 DASH_Dad2 PF08654.5 CCD24331.1 - 0.3 11.0 2.3 17 5.4 0.2 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad2 Mod_r PF07200.8 CCD24331.1 - 0.34 10.7 5.0 5.1 7.0 0.1 2.6 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein NPV_P10 PF05531.7 CCD24331.1 - 1.2 9.3 7.1 24 5.2 1.0 3.0 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ras PF00071.17 CCD24332.1 - 2e-53 180.1 0.0 2.4e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD24332.1 - 4.3e-14 53.0 0.0 6.7e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCD24332.1 - 3.3e-05 23.1 0.0 4.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCD24332.1 - 0.072 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Fmp27 PF10344.4 CCD24333.1 - 4.8e-136 454.7 63.0 4.8e-136 454.7 43.6 2.1 3 0 0 3 3 3 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.4 CCD24333.1 - 2.5e-107 359.2 6.1 2.5e-107 359.2 4.2 2.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 CCD24333.1 - 1.2e-93 314.5 23.5 3.4e-68 230.6 6.9 3.1 2 1 1 3 3 3 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 CCD24333.1 - 1.2e-53 181.2 0.1 3.2e-53 179.8 0.1 1.8 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CCD24333.1 - 7.6e-48 162.2 0.3 7e-47 159.0 0.2 2.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CCD24333.1 - 2.7e-33 114.4 0.9 1.9e-32 111.7 0.0 3.1 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain RRM_6 PF14259.1 CCD24334.1 - 8.5e-10 38.4 0.0 1.6e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCD24334.1 - 8.7e-05 22.0 0.0 0.00017 21.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD24334.1 - 0.037 13.8 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RGS PF00615.14 CCD24335.1 - 2.6e-16 59.7 3.5 3.7e-11 43.1 0.3 2.6 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.16 CCD24335.1 - 1.7e-12 46.8 0.0 1e-11 44.3 0.0 2.3 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Zn_clus PF00172.13 CCD24336.1 - 2.3e-08 33.8 10.4 4.5e-08 32.8 7.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2968 PF11180.3 CCD24336.1 - 0.019 14.3 0.1 0.019 14.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) Med26 PF08711.6 CCD24336.1 - 0.24 10.9 2.2 0.35 10.4 0.1 2.4 2 0 0 2 2 2 0 TFIIS helical bundle-like domain PBP1_TM PF14812.1 CCD24336.1 - 0.4 11.0 6.4 1.1 9.5 4.4 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MFS_1 PF07690.11 CCD24337.1 - 1.5e-21 76.5 22.2 5.4e-14 51.6 13.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 CCD24337.1 - 1.7e-06 26.8 7.2 1.7e-06 26.8 5.0 2.4 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 CCD24337.1 - 0.0038 15.6 10.0 0.0038 15.6 6.9 2.7 1 1 1 2 2 2 1 MFS/sugar transport protein Sugar_tr PF00083.19 CCD24337.1 - 0.0084 14.7 20.1 0.031 12.8 14.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 CCD24337.1 - 0.027 14.2 1.3 0.027 14.2 0.9 3.3 3 0 0 3 3 3 0 MFS_1 like family Ribosomal_S7 PF00177.16 CCD24338.1 - 6.9e-39 132.7 1.8 9.2e-39 132.3 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e GCV_T PF01571.16 CCD24339.1 - 1.2e-06 28.0 0.0 0.011 15.1 0.0 2.4 2 0 0 2 2 2 2 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CCD24339.1 - 0.14 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain ATP-synt_ab PF00006.20 CCD24340.1 - 3.2e-63 213.0 0.0 5.3e-63 212.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCD24340.1 - 1e-26 93.6 0.6 1.7e-26 92.8 0.4 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCD24340.1 - 4.5e-24 84.4 1.0 1.1e-23 83.1 0.7 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 CCD24340.1 - 0.00066 18.8 0.2 0.0012 18.0 0.1 1.4 1 0 0 1 1 1 1 KaiC MobB PF03205.9 CCD24340.1 - 0.0066 16.1 0.2 0.57 9.8 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 CCD24340.1 - 0.009 15.4 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CCD24340.1 - 0.017 14.0 0.8 0.53 9.0 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 CCD24340.1 - 0.02 14.5 0.1 0.069 12.8 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 CCD24340.1 - 0.035 14.1 0.9 0.25 11.2 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 CCD24340.1 - 0.038 14.1 0.1 0.52 10.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CCD24340.1 - 0.043 13.0 0.1 0.082 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCD24340.1 - 0.053 13.6 0.0 0.34 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CCD24340.1 - 0.057 13.1 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 CCD24340.1 - 0.079 13.1 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA helicase JmjC PF02373.17 CCD24341.1 - 1.4e-36 125.2 0.9 5.5e-36 123.2 0.6 2.2 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 CCD24341.1 - 2.2e-10 39.8 0.2 7.6e-10 38.1 0.0 2.1 2 0 0 2 2 2 1 jmjN domain PHD PF00628.24 CCD24341.1 - 0.0016 18.0 14.2 0.0016 18.0 9.9 2.4 2 0 0 2 2 2 1 PHD-finger Ilm1 PF10311.4 CCD24342.1 - 3.7e-41 140.3 8.8 5.6e-41 139.8 6.1 1.3 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 PCI PF01399.22 CCD24343.1 - 5.1e-20 71.7 1.2 8.6e-20 71.0 0.2 1.9 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 CCD24343.1 - 2.1e-19 69.6 0.2 4.8e-19 68.5 0.1 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI_Csn8 PF10075.4 CCD24343.1 - 0.01 15.6 0.1 0.023 14.4 0.1 1.6 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 Peptidase_M48 PF01435.13 CCD24344.1 - 4.8e-48 163.6 0.1 6.8e-48 163.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M48 DUF2268 PF10026.4 CCD24344.1 - 0.024 14.0 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) TRAM_LAG1_CLN8 PF03798.11 CCD24345.1 - 1.9e-32 112.4 22.7 1.9e-32 112.4 15.7 1.6 2 0 0 2 2 2 1 TLC domain PfkB PF00294.19 CCD24346.1 - 2.8e-69 233.5 0.8 3.7e-69 233.1 0.6 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CCD24346.1 - 0.00012 21.3 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase DUF3615 PF12274.3 CCD24346.1 - 0.052 13.8 1.1 0.11 12.8 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3615) Na_Ca_ex PF01699.19 CCD24347.1 - 1.8e-51 173.4 25.4 2e-30 105.2 5.9 2.9 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Lipase_3 PF01764.20 CCD24348.1 - 3.7e-36 123.8 0.0 1.1e-35 122.3 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.3 CCD24348.1 - 0.0082 15.5 0.2 0.48 9.7 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2974) DUF3173 PF11372.3 CCD24348.1 - 0.0096 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3173) LOH1CR12 PF10158.4 CCD24349.1 - 0.19 11.5 4.1 0.21 11.3 2.9 1.1 1 0 0 1 1 1 0 Tumour suppressor protein Bac_small_YrzI PF09501.5 CCD24349.1 - 0.27 11.1 3.3 0.51 10.2 2.1 1.8 1 1 0 1 1 1 0 Probable sporulation protein (Bac_small_yrzI) CPSase_L_D2 PF02786.12 CCD24350.1 - 2.7e-112 373.1 0.0 1.5e-84 282.5 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 CCD24350.1 - 2.1e-39 134.0 1.3 3.9e-39 133.2 0.2 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 CCD24350.1 - 4.7e-37 127.5 0.4 1.1e-20 74.1 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 CCD24350.1 - 3e-34 117.4 0.0 7.5e-16 58.2 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 CCD24350.1 - 8.6e-24 83.8 0.0 1.4e-09 37.1 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CCD24350.1 - 6.5e-19 67.9 0.0 2.1e-09 36.9 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCD24350.1 - 7.5e-15 54.8 0.5 6.9e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 CCD24350.1 - 1.5e-08 34.3 0.1 0.0037 16.7 0.0 2.6 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CCD24350.1 - 2.4e-05 24.2 0.2 0.019 14.8 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain GARS_A PF01071.14 CCD24350.1 - 0.0011 18.6 0.2 1.9 7.9 0.0 2.8 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MGS PF02142.17 CCD24350.1 - 0.0052 16.7 0.1 0.021 14.7 0.0 2.1 2 0 0 2 2 1 1 MGS-like domain ATP-grasp_5 PF13549.1 CCD24350.1 - 0.014 14.6 0.0 0.18 10.9 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain Epimerase PF01370.16 CCD24350.1 - 0.016 14.6 0.0 0.91 8.8 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family MCPsignal PF00015.16 CCD24350.1 - 0.068 12.7 0.3 0.17 11.4 0.0 1.8 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Yippee-Mis18 PF03226.9 CCD24351.1 - 2.6e-17 62.6 2.1 5.4e-17 61.6 1.5 1.6 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2079 PF09852.4 CCD24351.1 - 0.0009 18.0 0.6 0.0011 17.7 0.4 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2079) MASE2 PF05230.6 CCD24351.1 - 0.037 14.0 0.0 0.38 10.7 0.0 2.1 2 0 0 2 2 2 0 MASE2 domain Myotub-related PF06602.9 CCD24352.1 - 5.8e-120 400.2 0.5 8.2e-120 399.7 0.4 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 CCD24352.1 - 0.001 18.5 0.3 0.0039 16.6 0.0 2.2 2 0 0 2 2 2 1 GRAM domain Y_phosphatase3 PF13350.1 CCD24352.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 CCD24352.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCD24352.1 - 0.049 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PK_C PF02887.11 CCD24352.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain CMD PF02627.15 CCD24353.1 - 8.6e-05 22.2 0.0 0.00023 20.9 0.0 1.7 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Ribosomal_S7 PF00177.16 CCD24354.1 - 2.7e-31 108.1 0.8 4e-31 107.6 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e ELFV_dehydrog PF00208.16 CCD24354.1 - 0.1 12.1 0.2 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TcdB_N PF12918.2 CCD24354.1 - 0.1 12.6 1.9 0.35 10.9 0.2 2.3 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Elicitin PF00964.12 CCD24355.1 - 0.53 10.2 5.3 1 9.3 1.8 2.6 2 1 0 2 2 2 0 Elicitin Sod_Cu PF00080.15 CCD24356.1 - 6.4e-45 152.7 4.4 7.6e-45 152.5 3.0 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) ESCRT-II PF05871.7 CCD24357.1 - 4.6e-45 152.9 8.6 6.2e-45 152.5 5.9 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit Sod_Fe_C PF02777.13 CCD24358.1 - 6.9e-11 41.9 0.5 4.6e-05 23.2 0.1 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Scramblase PF03803.10 CCD24359.1 - 8.6e-69 230.9 0.1 1.1e-68 230.5 0.1 1.1 1 0 0 1 1 1 1 Scramblase KRTDAP PF15200.1 CCD24359.1 - 0.095 12.4 1.8 0.26 11.0 0.4 2.3 2 0 0 2 2 2 0 Keratinocyte differentiation-associated Tub_2 PF04525.7 CCD24359.1 - 0.12 11.7 0.3 13 5.1 0.0 2.7 2 1 1 3 3 3 0 Tubby C 2 DUF3278 PF11683.3 CCD24360.1 - 1.8 8.5 6.4 1.7 8.6 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Peptidase_C12 PF01088.16 CCD24362.1 - 1.4e-49 168.1 0.1 1.6e-49 167.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 LCAT PF02450.10 CCD24363.1 - 1.7e-06 27.2 0.0 3.7e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CCD24363.1 - 4e-06 26.8 0.0 7.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CCD24363.1 - 7.6e-06 25.6 0.0 2.4e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_1 PF00561.15 CCD24363.1 - 0.00022 20.8 0.0 0.00054 19.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCD24363.1 - 0.00093 18.9 0.0 0.0026 17.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CCD24363.1 - 0.0025 17.4 0.2 0.0065 16.0 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase DUF900 PF05990.7 CCD24363.1 - 0.0061 15.9 0.0 0.016 14.5 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) DUF572 PF04502.8 CCD24363.1 - 0.04 13.1 9.7 0.068 12.3 6.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) CAML PF14963.1 CCD24363.1 - 0.11 11.8 5.1 0.22 10.8 3.5 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Mem_trans PF03547.13 CCD24363.1 - 0.12 10.6 3.9 0.19 10.0 2.7 1.2 1 0 0 1 1 1 0 Membrane transport protein DnaJ PF00226.26 CCD24364.1 - 1.4e-17 63.1 0.3 2.7e-17 62.2 0.2 1.5 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 CCD24364.1 - 3e-16 58.6 0.4 5.4e-16 57.8 0.3 1.4 1 0 0 1 1 1 1 CSL zinc finger Mu-like_Com PF10122.4 CCD24364.1 - 0.0086 15.1 0.3 0.023 13.7 0.2 1.7 1 0 0 1 1 1 1 Mu-like prophage protein Com DUF4162 PF13732.1 CCD24364.1 - 0.062 13.8 0.4 0.15 12.5 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4162) Acetyltransf_11 PF13720.1 CCD24364.1 - 0.073 13.3 0.1 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 RPT PF13446.1 CCD24364.1 - 0.096 12.1 0.2 2.5 7.5 0.0 2.4 2 0 0 2 2 2 0 A repeated domain in UCH-protein HypA PF01155.14 CCD24364.1 - 0.14 11.8 1.2 0.32 10.7 0.8 1.7 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family E7 PF00527.13 CCD24364.1 - 0.48 10.6 2.5 0.88 9.7 0.1 2.4 1 1 1 2 2 2 0 E7 protein, Early protein Mito_carr PF00153.22 CCD24365.1 - 1e-73 243.1 4.4 5e-24 83.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF500 PF04366.7 CCD24365.1 - 0.0011 18.3 0.9 0.0023 17.3 0.6 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) Fip1 PF05182.8 CCD24367.1 - 1.7e-21 75.2 0.3 3.2e-21 74.3 0.2 1.5 1 0 0 1 1 1 1 Fip1 motif Anillin PF08174.6 CCD24368.1 - 2.4e-06 27.6 0.0 8.6e-06 25.8 0.0 2.0 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 CCD24368.1 - 5e-06 26.6 2.7 1.1e-05 25.5 0.0 3.1 3 0 0 3 3 3 1 PH domain PUF PF00806.14 CCD24369.1 - 1.1e-28 97.0 1.8 9e-06 24.8 0.0 6.7 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_5 PF13893.1 CCD24369.1 - 8.8e-08 31.8 0.0 2.4e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCD24369.1 - 1.4e-06 27.8 0.0 3.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD24369.1 - 0.0035 17.2 0.0 0.0093 15.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) BIR PF00653.16 CCD24371.1 - 1e-09 38.6 10.4 1.9e-07 31.4 1.6 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Evr1_Alr PF04777.8 CCD24372.1 - 8.4e-25 86.5 0.9 1.4e-24 85.8 0.6 1.4 1 0 0 1 1 1 1 Erv1 / Alr family Herpes_UL69 PF05459.7 CCD24372.1 - 0.0044 16.1 0.1 0.042 13.0 0.0 2.1 1 1 1 2 2 2 1 Herpesvirus transcriptional regulator family Serinc PF03348.10 CCD24372.1 - 0.022 13.4 0.1 0.03 13.0 0.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Toxin-deaminase PF14424.1 CCD24372.1 - 0.066 13.1 0.1 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases DUF4199 PF13858.1 CCD24372.1 - 0.13 12.2 0.1 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) G-gamma PF00631.17 CCD24373.1 - 3.9e-25 87.3 0.1 6.3e-25 86.7 0.1 1.4 1 0 0 1 1 1 1 GGL domain Herpes_UL95 PF03038.9 CCD24373.1 - 0.019 13.8 0.1 0.023 13.5 0.1 1.1 1 0 0 1 1 1 0 UL95 family Aldo_ket_red PF00248.16 CCD24374.1 - 5.1e-45 153.4 0.1 6.4e-45 153.1 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ENTH PF01417.15 CCD24375.1 - 4.5e-39 133.1 0.5 4.5e-39 133.1 0.4 1.8 2 0 0 2 2 2 1 ENTH domain UPF0560 PF10577.4 CCD24375.1 - 0.93 7.6 34.3 0.11 10.7 20.9 1.5 1 1 0 1 1 1 0 Uncharacterised protein family UPF0560 Sel1 PF08238.7 CCD24376.1 - 1.9e-22 79.1 0.7 5.4e-05 23.6 0.0 7.9 8 0 0 8 8 7 3 Sel1 repeat TPR_16 PF13432.1 CCD24376.1 - 2.4e-05 24.8 0.0 0.03 15.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCD24376.1 - 6.2e-05 23.1 0.5 2.1 8.9 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCD24376.1 - 0.00012 21.6 6.1 0.011 15.4 0.0 5.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCD24376.1 - 0.00051 20.3 0.2 0.83 10.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCD24376.1 - 0.00063 20.1 0.0 2.1 9.1 0.0 3.4 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCD24376.1 - 0.0069 16.1 1.0 0.24 11.2 0.0 4.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CCD24376.1 - 0.0076 16.3 0.3 0.76 9.9 0.0 3.3 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CCD24376.1 - 0.0082 15.7 11.9 0.18 11.4 0.1 6.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCD24376.1 - 0.0087 15.6 8.1 0.08 12.5 0.1 4.1 3 1 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 CCD24376.1 - 0.012 15.5 4.9 1.3 9.0 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCD24376.1 - 0.016 15.0 12.3 0.32 11.0 0.0 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat WD40 PF00400.27 CCD24377.1 - 6.6e-40 133.5 20.1 1.6e-09 37.2 0.2 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 CCD24377.1 - 0.0017 18.1 4.2 0.15 11.7 1.0 3.1 1 1 2 3 3 3 2 Transcription factor IIIC subunit delta N-term PNP_UDP_1 PF01048.15 CCD24378.1 - 1.9e-42 144.8 0.0 2.4e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Cyclin_N PF00134.18 CCD24379.1 - 2.3e-43 146.7 0.3 6.3e-43 145.3 0.2 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCD24379.1 - 2e-26 92.2 0.0 6.1e-26 90.6 0.0 1.9 1 0 0 1 1 1 1 Cyclin, C-terminal domain zf-CCHC_4 PF14392.1 CCD24380.1 - 0.27 10.9 1.9 0.49 10.0 1.3 1.4 1 0 0 1 1 1 0 Zinc knuckle rve PF00665.21 CCD24382.1 - 9.4e-18 64.4 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CCD24382.1 - 0.053 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Slx4 PF09494.5 CCD24382.1 - 0.075 12.7 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Slx4 endonuclease Imm6 PF14434.1 CCD24382.1 - 0.14 11.8 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Immunity protein Imm6 Flo11 PF10182.4 CCD24383.1 - 1.4e-51 174.0 1.3 4.2e-51 172.4 0.9 1.9 1 0 0 1 1 1 1 Flo11 domain DUF2216 PF10226.4 CCD24384.1 - 0.013 15.0 0.4 0.013 15.0 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) Ribosomal_L17 PF01196.14 CCD24384.1 - 0.063 13.8 2.2 0.076 13.5 0.2 2.2 3 1 0 3 3 3 0 Ribosomal protein L17 Spectrin PF00435.16 CCD24384.1 - 0.77 10.0 14.6 0.046 14.0 1.0 2.8 2 1 0 2 2 2 0 Spectrin repeat Prp18 PF02840.10 CCD24384.1 - 2.2 8.0 7.7 0.13 12.0 0.4 2.4 2 1 1 3 3 3 0 Prp18 domain DUF2536 PF10750.4 CCD24384.1 - 2.3 7.8 6.4 0.38 10.3 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) APC_CDC26 PF10471.4 CCD24384.1 - 3.1 8.5 9.3 1.5 9.5 0.8 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit 1 STAT_int PF02865.12 CCD24384.1 - 3.5 7.5 9.3 1.3 8.9 0.7 2.5 2 1 0 2 2 2 0 STAT protein, protein interaction domain DUF948 PF06103.6 CCD24384.1 - 8.2 6.3 8.4 16 5.4 2.3 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Tubulin PF00091.20 CCD24385.1 - 1.9e-66 224.0 0.1 5e-66 222.6 0.1 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCD24385.1 - 2.5e-20 72.7 0.3 5.5e-20 71.6 0.2 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CCD24385.1 - 7.2e-07 29.2 0.7 2.4e-06 27.5 0.5 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Glyco_hydro_16 PF00722.16 CCD24386.1 - 4.7e-43 146.6 0.4 7.7e-43 145.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SAP18 PF06487.7 CCD24386.1 - 0.079 12.7 0.0 0.21 11.3 0.0 1.8 1 0 0 1 1 1 0 Sin3 associated polypeptide p18 (SAP18) Chitin_bind_1 PF00187.14 CCD24386.1 - 2.6 8.1 11.1 5 7.1 7.7 1.4 1 0 0 1 1 1 0 Chitin recognition protein Cellulase PF00150.13 CCD24387.1 - 1.4e-14 53.9 0.3 1.4e-14 53.9 0.2 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) 60KD_IMP PF02096.15 CCD24387.1 - 0.11 12.1 0.1 0.22 11.1 0.0 1.5 2 0 0 2 2 2 0 60Kd inner membrane protein DUF3783 PF12646.2 CCD24387.1 - 0.35 10.6 1.0 1.7 8.4 0.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3783) SNF2_N PF00176.18 CCD24388.1 - 3.9e-64 216.2 0.0 1.1e-63 214.7 0.0 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCD24388.1 - 6e-10 38.8 0.0 1.8e-09 37.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 CCD24388.1 - 4.5e-05 23.0 4.7 0.00011 21.9 3.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCD24388.1 - 5.5e-05 22.7 1.6 0.00012 21.6 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD24388.1 - 0.00018 21.4 1.8 0.00049 20.0 1.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCD24388.1 - 0.00059 19.6 5.3 0.0014 18.4 3.6 1.7 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.1 CCD24388.1 - 0.0047 16.4 0.7 0.013 15.0 0.5 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.20 CCD24388.1 - 0.03 13.9 5.2 0.065 12.9 3.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCD24388.1 - 0.08 12.6 0.6 0.25 11.0 0.4 1.9 1 0 0 1 1 1 0 RING-type zinc-finger KA1 PF02149.14 CCD24390.1 - 0.079 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinase associated domain 1 Hydantoinase_B PF02538.9 CCD24391.1 - 2.6e-218 725.5 0.1 3.3e-218 725.2 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 CCD24391.1 - 2.9e-91 305.5 0.4 6.8e-91 304.3 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 CCD24391.1 - 5.6e-55 185.5 0.8 5.1e-53 179.1 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region DUF367 PF04034.8 CCD24393.1 - 3.3e-51 172.1 0.0 6.7e-51 171.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CCD24393.1 - 1e-13 50.5 0.2 2e-13 49.6 0.2 1.5 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI VPS9 PF02204.13 CCD24394.1 - 5.3e-08 32.8 1.6 1.8e-07 31.1 1.1 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 CCD24394.1 - 6.8e-05 23.1 4.1 0.038 14.3 0.1 3.8 3 1 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCD24394.1 - 0.00024 21.2 0.0 0.43 10.8 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD24394.1 - 0.0059 16.7 0.4 97 3.6 0.0 5.4 5 0 0 5 5 5 0 Ankyrin repeat TPR_11 PF13414.1 CCD24395.1 - 1.7e-28 98.0 6.3 7.5e-19 67.1 1.6 2.8 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CCD24395.1 - 4e-20 70.5 7.0 3e-07 29.7 0.2 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCD24395.1 - 1.2e-15 56.0 8.9 5.9e-05 22.6 0.2 4.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCD24395.1 - 2.2e-08 33.6 3.3 0.0015 18.5 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCD24395.1 - 3.7e-08 33.1 2.4 9e-07 28.7 0.7 3.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCD24395.1 - 1.6e-07 31.8 0.3 0.00033 21.2 0.0 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCD24395.1 - 2.1e-07 30.1 6.2 0.01 15.5 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCD24395.1 - 1.8e-06 28.0 0.0 0.044 14.4 0.0 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCD24395.1 - 6.5e-06 25.9 1.1 0.1 12.4 0.0 3.6 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 CCD24395.1 - 1.6e-05 25.1 0.6 0.0074 16.5 0.0 2.9 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCD24395.1 - 0.00016 21.2 0.5 1.3 9.0 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.12 CCD24395.1 - 0.00049 20.4 0.0 0.0024 18.1 0.0 1.9 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_9 PF13371.1 CCD24395.1 - 0.0041 16.9 0.0 0.019 14.7 0.0 2.1 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CCD24395.1 - 0.014 15.5 2.3 0.055 13.5 1.5 2.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCD24395.1 - 0.031 14.7 1.1 1.7 9.2 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.2 CCD24395.1 - 0.032 14.0 5.2 4.8 7.0 1.2 3.4 2 2 0 2 2 2 0 Domain of Unknown Function (DUF3856) TPR_15 PF13429.1 CCD24395.1 - 0.035 13.1 0.5 0.19 10.7 0.1 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat PSD4 PF07631.6 CCD24395.1 - 0.07 13.5 1.3 0.13 12.6 0.1 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1592) MIT PF04212.13 CCD24395.1 - 0.63 9.9 7.6 24 4.8 1.0 4.0 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Sugar_tr PF00083.19 CCD24396.1 - 1.1e-162 541.6 33.3 1.3e-162 541.4 23.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD24396.1 - 6.8e-33 113.8 21.8 6.8e-33 113.8 15.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pirin PF02678.11 CCD24397.1 - 8.4e-30 102.8 0.1 3.4e-29 100.8 0.0 1.9 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 CCD24397.1 - 3.4e-19 68.8 0.0 2.3e-18 66.1 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 CCD24397.1 - 0.00015 21.1 1.8 0.00027 20.3 0.6 1.9 2 0 0 2 2 2 1 Cupin domain Ras PF00071.17 CCD24398.1 - 6.3e-56 188.2 0.3 7.5e-56 187.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD24398.1 - 4.9e-19 68.9 0.0 8.1e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCD24398.1 - 1.5e-15 56.8 0.0 1.8e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCD24398.1 - 4.9e-08 32.4 0.3 6e-08 32.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCD24398.1 - 3.2e-07 29.9 0.1 7.4e-06 25.5 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCD24398.1 - 5.3e-06 26.3 0.0 1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CCD24398.1 - 6e-05 23.2 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 CCD24398.1 - 0.00011 21.4 0.2 0.00015 21.0 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 CCD24398.1 - 0.00059 19.4 0.2 0.019 14.4 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 CCD24398.1 - 0.00068 19.6 0.0 0.0087 16.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 CCD24398.1 - 0.004 16.7 0.0 0.0099 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 CCD24398.1 - 0.0045 16.4 0.0 0.013 14.9 0.0 1.7 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CCD24398.1 - 0.0064 15.7 0.2 0.013 14.7 0.0 1.6 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CCD24398.1 - 0.0087 15.7 0.4 0.022 14.4 0.3 1.9 1 1 0 1 1 1 1 Archaeal ATPase NTPase_1 PF03266.10 CCD24398.1 - 0.0094 15.6 0.1 0.036 13.7 0.0 1.8 2 0 0 2 2 2 1 NTPase MobB PF03205.9 CCD24398.1 - 0.014 15.1 0.1 0.038 13.6 0.0 1.7 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 CCD24398.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 CCD24398.1 - 0.024 14.1 0.4 0.075 12.5 0.3 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CCD24398.1 - 0.053 12.5 0.3 0.22 10.5 0.0 2.0 2 1 1 3 3 3 0 Septin NB-ARC PF00931.17 CCD24398.1 - 0.065 12.0 0.0 0.11 11.2 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 CCD24398.1 - 0.068 12.5 0.0 0.15 11.4 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain ABC_tran PF00005.22 CCD24398.1 - 0.17 12.2 0.4 0.26 11.6 0.3 1.7 1 1 0 1 1 1 0 ABC transporter DNA_pol_A_exo1 PF01612.15 CCD24399.1 - 4e-46 156.7 1.1 5.6e-45 152.9 0.1 2.4 2 0 0 2 2 2 1 3'-5' exonuclease PMC2NT PF08066.7 CCD24399.1 - 4.6e-25 87.7 9.3 1.2e-23 83.2 2.7 3.3 2 0 0 2 2 2 2 PMC2NT (NUC016) domain HRDC PF00570.18 CCD24399.1 - 2.7e-13 49.4 0.0 5.8e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 HRDC domain NPR2 PF06218.6 CCD24400.1 - 1.3e-156 521.6 15.4 1.3e-156 521.6 10.7 1.7 2 0 0 2 2 2 1 Nitrogen permease regulator 2 NPR3 PF03666.8 CCD24400.1 - 2.7e-05 22.9 25.3 0.0065 15.0 0.1 5.1 5 0 0 5 5 5 5 Nitrogen Permease regulator of amino acid transport activity 3 Kinesin PF00225.18 CCD24401.1 - 2.2e-96 322.5 21.6 1.5e-61 207.9 5.0 3.1 3 0 0 3 3 3 2 Kinesin motor domain Cob_adeno_trans PF01923.13 CCD24401.1 - 0.51 10.1 9.5 0.15 11.8 1.2 3.5 2 1 0 3 3 3 0 Cobalamin adenosyltransferase Cpn60_TCP1 PF00118.19 CCD24402.1 - 1.4e-119 399.9 8.0 1.6e-119 399.7 5.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_I_TF PF04090.7 CCD24403.1 - 2.3e-70 235.9 2.2 2.3e-70 235.9 1.5 2.5 2 0 0 2 2 2 1 RNA polymerase I specific initiation factor IMS_HHH PF11798.3 CCD24403.1 - 0.062 13.3 0.3 0.18 11.9 0.2 1.7 1 0 0 1 1 1 0 IMS family HHH motif Zn_clus PF00172.13 CCD24404.1 - 9.9e-09 34.9 10.4 9.9e-09 34.9 7.2 2.0 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 CCD24405.1 - 1.5e-21 76.8 0.0 2.1e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCD24405.1 - 2.2e-12 46.2 0.1 3.2e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCD24405.1 - 6.9e-09 35.9 0.2 1.8e-08 34.5 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCD24405.1 - 4.3e-07 29.1 0.0 9.7e-07 27.9 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 CCD24405.1 - 0.00011 21.1 0.1 0.0023 16.9 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CCD24405.1 - 0.00048 19.4 0.1 0.0036 16.5 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 CCD24405.1 - 0.0006 19.7 0.0 0.0024 17.8 0.0 2.0 2 1 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.12 CCD24405.1 - 0.011 16.1 0.1 0.03 14.7 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 CCD24405.1 - 0.021 14.4 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 CCD24405.1 - 0.06 13.6 0.0 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CCD24405.1 - 0.11 12.3 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus PLA2_B PF01735.13 CCD24406.1 - 8e-232 769.7 6.1 1e-231 769.3 4.2 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain TAF4 PF05236.9 CCD24407.1 - 2.1e-64 217.3 3.7 3.2e-64 216.7 2.6 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family E1-E2_ATPase PF00122.15 CCD24407.1 - 0.032 13.2 0.1 0.048 12.6 0.1 1.2 1 0 0 1 1 1 0 E1-E2 ATPase DUF544 PF04424.8 CCD24408.1 - 7e-28 96.8 0.8 1.5e-27 95.8 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF544) Dicty_REP PF05086.7 CCD24408.1 - 0.00056 17.8 0.8 0.00078 17.3 0.6 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein EF-hand_1 PF00036.27 CCD24408.1 - 0.026 13.7 0.0 0.97 8.8 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 CCD24408.1 - 0.042 13.7 0.0 3 7.9 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain DUF3439 PF11921.3 CCD24408.1 - 0.07 12.8 1.2 0.12 12.1 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) EF-hand_5 PF13202.1 CCD24408.1 - 0.1 11.9 0.1 7.4 6.1 0.0 2.6 2 0 0 2 2 2 0 EF hand bPH_3 PF14470.1 CCD24409.1 - 0.023 14.9 2.2 0.058 13.6 0.1 2.2 2 0 0 2 2 2 0 Bacterial PH domain GP40 PF11025.3 CCD24409.1 - 0.11 12.0 1.3 0.18 11.4 0.9 1.4 1 1 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium CDC45 PF02724.9 CCD24409.1 - 1.2 7.0 11.3 1.4 6.8 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2202 PF09968.4 CCD24410.1 - 0.031 13.9 0.3 0.043 13.4 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) NUFIP1 PF10453.4 CCD24411.1 - 5.6e-17 61.0 1.0 5.6e-17 61.0 0.7 2.6 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) RRM_1 PF00076.17 CCD24412.1 - 3.8e-10 39.2 0.1 9.3e-10 38.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD24412.1 - 5e-07 29.5 0.0 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD24412.1 - 0.032 14.0 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUN PF03856.8 CCD24413.1 - 5.4e-105 350.1 13.1 9.5e-105 349.3 9.1 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) MFS_1 PF07690.11 CCD24415.1 - 8.5e-39 133.2 15.6 8.5e-39 133.2 10.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCD24415.1 - 1.3e-17 63.5 8.9 1.5e-16 60.0 2.3 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 CCD24415.1 - 6.9e-05 21.2 2.7 0.00011 20.5 1.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.4 CCD24415.1 - 0.055 13.8 3.1 3.5 8.0 0.1 3.1 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) YqhR PF11085.3 CCD24415.1 - 0.092 12.2 5.0 0.15 11.6 0.2 3.1 1 1 1 3 3 3 0 Conserved membrane protein YqhR DnaJ PF00226.26 CCD24416.1 - 6.2e-28 96.3 2.0 1.1e-27 95.5 1.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCD24416.1 - 3e-21 75.0 0.5 3e-18 65.4 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCD24416.1 - 8e-14 51.4 16.8 1.3e-13 50.7 11.7 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CCD24416.1 - 0.00064 19.3 7.0 0.057 13.1 0.7 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrome_C7 PF14522.1 CCD24416.1 - 6 6.5 8.3 23 4.6 5.7 2.1 1 1 0 1 1 1 0 Cytochrome c7 Gcd10p PF04189.8 CCD24417.1 - 5.3e-98 327.8 2.6 6.5e-98 327.5 1.8 1.1 1 0 0 1 1 1 1 Gcd10p family Nol1_Nop2_Fmu PF01189.12 CCD24418.1 - 1.7e-108 362.2 0.0 3.1e-108 361.4 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 CCD24418.1 - 0.00076 19.0 0.0 0.0021 17.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 CCD24418.1 - 0.0013 18.7 0.0 0.0038 17.2 0.0 1.8 1 0 0 1 1 1 1 FtsJ-like methyltransferase Actin PF00022.14 CCD24419.1 - 2e-54 184.5 0.0 9.7e-32 109.8 0.0 2.3 2 0 0 2 2 2 2 Actin Y_phosphatase2 PF03162.8 CCD24421.1 - 1.4e-51 174.1 0.0 1.5e-51 173.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCD24421.1 - 6.8e-06 26.4 0.0 8.5e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Vac7 PF12751.2 CCD24422.1 - 1.4e-22 80.1 2.2 6.1e-15 54.9 0.0 4.1 4 0 0 4 4 4 2 Vacuolar segregation subunit 7 DSPc PF00782.15 CCD24423.1 - 1.9e-35 121.3 0.6 5.2e-35 119.9 0.4 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCD24423.1 - 0.00079 18.8 0.0 0.0025 17.1 0.0 1.8 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCD24423.1 - 0.019 15.0 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 Inositol hexakisphosphate COG5 PF10392.4 CCD24424.1 - 1.2e-38 132.0 6.3 1.2e-38 132.0 4.3 3.1 3 1 0 3 3 3 1 Golgi transport complex subunit 5 DUF2011 PF09428.5 CCD24425.1 - 7.4e-31 106.7 13.1 1e-30 106.2 9.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Sec23_trunk PF04811.10 CCD24426.1 - 3e-66 223.2 0.0 6.7e-66 222.1 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCD24426.1 - 8.3e-23 79.7 0.6 8.3e-23 79.7 0.4 2.1 2 0 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CCD24426.1 - 7.4e-15 54.2 6.7 1.4e-14 53.3 4.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CCD24426.1 - 2.1e-14 53.7 0.0 4.3e-14 52.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CCD24426.1 - 2.9e-09 36.4 0.0 1.2e-08 34.4 0.0 2.1 2 0 0 2 2 2 1 Gelsolin repeat UQ_con PF00179.21 CCD24427.1 - 1.2e-38 131.6 0.1 1.6e-38 131.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCD24427.1 - 0.077 12.9 0.1 0.12 12.2 0.1 1.5 1 1 0 1 1 1 0 RWD domain Na_trans_assoc PF06512.8 CCD24427.1 - 3 7.7 8.8 5 7.0 6.1 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated Vfa1 PF08432.5 CCD24427.1 - 7.5 6.5 7.8 16 5.4 5.4 1.6 1 1 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Alpha-amylase_C PF02806.13 CCD24428.1 - 3e-26 91.3 0.6 1.5e-25 89.1 0.1 2.4 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CCD24428.1 - 1.5e-18 67.2 0.3 1.4e-16 60.8 0.1 3.0 1 1 1 2 2 2 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 CCD24428.1 - 6e-13 48.6 0.1 1.4e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_66 PF13199.1 CCD24428.1 - 0.0055 15.1 0.6 0.0076 14.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 66 zf-CCHC PF00098.18 CCD24430.1 - 2.6e-06 27.1 2.1 4.7e-06 26.2 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF637 PF04830.8 CCD24430.1 - 0.033 13.8 4.3 0.026 14.1 1.8 1.8 2 0 0 2 2 2 0 Possible hemagglutinin (DUF637) Retrotrans_gag PF03732.12 CCD24430.1 - 0.055 13.5 0.1 0.18 11.8 0.0 1.9 1 1 0 1 1 1 0 Retrotransposon gag protein eIF3g PF12353.3 CCD24430.1 - 0.058 13.3 0.8 0.15 11.9 0.5 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G ApbA_C PF08546.6 CCD24430.1 - 0.096 12.6 0.0 0.85 9.6 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal FAD_binding_1 PF00667.15 CCD24431.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain DUF2373 PF10180.4 CCD24432.1 - 3.9e-27 93.5 0.2 7.4e-27 92.6 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) Biotin_carb_C PF02785.14 CCD24432.1 - 0.067 13.1 0.0 0.17 11.9 0.0 1.6 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain HAD PF12710.2 CCD24433.1 - 4.6e-13 49.7 0.0 6.6e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 CCD24433.1 - 0.002 17.3 0.0 0.65 9.1 0.0 2.3 2 0 0 2 2 2 2 Putative Phosphatase Grp1_Fun34_YaaH PF01184.14 CCD24434.1 - 4.2e-94 313.7 15.3 4.9e-94 313.5 10.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3953 PF13129.1 CCD24434.1 - 0.028 14.0 2.6 0.028 14.0 1.8 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3953) DUF997 PF06196.7 CCD24434.1 - 0.21 11.1 5.2 2.1 7.9 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF997) DUF373 PF04123.8 CCD24434.1 - 1.3 7.9 5.3 0.75 8.7 2.3 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Flo11 PF10182.4 CCD24435.1 - 6.1e-52 175.2 3.3 1.3e-51 174.1 2.3 1.6 1 0 0 1 1 1 1 Flo11 domain RVT_2 PF07727.9 CCD24436.1 - 0.0014 17.6 0.0 0.0023 16.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PRA1 PF03208.14 CCD24437.1 - 5.5e-39 132.9 2.0 6.3e-39 132.7 1.4 1.1 1 0 0 1 1 1 1 PRA1 family protein IncA PF04156.9 CCD24437.1 - 0.097 12.2 0.2 0.097 12.2 0.1 2.9 3 0 0 3 3 3 0 IncA protein DUF4190 PF13828.1 CCD24437.1 - 4.8 6.8 8.9 3.3 7.3 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Peptidase_M1 PF01433.15 CCD24438.1 - 2.7e-76 257.1 0.0 3.8e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 CCD24438.1 - 4.3e-44 149.6 0.1 8.9e-44 148.5 0.1 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 CCD24438.1 - 2e-15 56.9 0.1 3.3e-15 56.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M64 PF09471.5 CCD24438.1 - 0.052 13.1 0.1 0.092 12.3 0.0 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 Peptidase_M61 PF05299.7 CCD24438.1 - 0.17 11.9 1.8 1.1 9.2 1.3 2.2 1 1 0 1 1 1 0 M61 glycyl aminopeptidase Glycos_transf_1 PF00534.15 CCD24440.1 - 8.3e-13 48.1 0.0 1.6e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCD24440.1 - 0.0021 18.2 0.0 0.0063 16.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF2220 PF09983.4 CCD24440.1 - 0.0025 17.0 0.0 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria C-term(DUF2220) Arm PF00514.18 CCD24441.1 - 5.5e-67 219.5 28.4 4.8e-12 45.2 0.0 10.5 11 0 0 11 11 11 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CCD24441.1 - 5.5e-23 81.0 7.8 8e-07 29.2 0.0 7.0 2 2 3 5 5 5 5 HEAT repeats HEAT_EZ PF13513.1 CCD24441.1 - 5.2e-15 55.4 13.2 0.00044 20.6 0.2 7.8 7 1 3 10 10 8 4 HEAT-like repeat HEAT PF02985.17 CCD24441.1 - 5.7e-14 50.8 23.1 0.013 15.4 0.0 10.4 11 0 0 11 11 11 3 HEAT repeat Adaptin_N PF01602.15 CCD24441.1 - 3.4e-12 45.4 12.5 6.5e-08 31.3 1.7 2.6 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 CCD24441.1 - 8.7e-11 40.4 4.2 6.5e-09 34.2 0.2 2.9 1 1 1 2 2 2 2 Kinesin-associated protein (KAP) Arm_2 PF04826.8 CCD24441.1 - 1.3e-09 37.5 11.7 0.0014 17.8 0.5 4.3 3 1 1 4 4 4 3 Armadillo-like DUF2454 PF10521.4 CCD24441.1 - 3e-06 26.4 0.2 0.0026 16.8 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2454) V-ATPase_H_N PF03224.9 CCD24441.1 - 5.2e-05 22.5 5.7 0.00081 18.6 0.8 3.4 1 1 2 3 3 3 2 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 CCD24441.1 - 0.00015 22.0 1.3 0.6 10.5 0.0 3.8 3 1 0 3 3 3 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 CCD24441.1 - 0.0055 16.3 2.8 0.063 12.9 0.3 3.0 2 1 0 3 3 3 1 rRNA processing/ribosome biogenesis DUF1981 PF09324.5 CCD24441.1 - 0.04 13.4 0.3 25 4.5 0.0 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF1981) RasGEF_N_2 PF14663.1 CCD24441.1 - 0.15 11.9 1.9 7.5 6.5 0.0 3.7 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain YjeF_N PF03853.10 CCD24442.1 - 2.6e-15 56.4 0.0 5.5e-15 55.3 0.0 1.5 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 CCD24442.1 - 8.6e-06 26.2 12.1 8.6e-06 26.2 8.4 4.4 4 1 0 4 4 4 1 FDF domain eRF1_2 PF03464.10 CCD24443.1 - 1.7e-31 109.2 0.1 3.4e-31 108.3 0.1 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CCD24443.1 - 1.1e-23 83.5 0.1 3.4e-23 82.0 0.1 1.8 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CCD24443.1 - 2.3e-10 40.1 0.1 3.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Cass2 PF14526.1 CCD24443.1 - 0.024 14.6 1.1 0.054 13.5 0.1 2.0 1 1 1 2 2 2 0 Integron-associated effector binding protein Septin PF00735.13 CCD24444.1 - 8.6e-106 353.0 2.9 1e-105 352.7 2.0 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCD24444.1 - 2.2e-09 37.2 0.4 4.3e-09 36.3 0.2 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCD24444.1 - 1.2e-07 31.0 0.1 2.2e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CCD24444.1 - 9.4e-07 28.8 1.6 0.04 13.7 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 CCD24444.1 - 5.6e-06 25.6 0.6 1.4e-05 24.2 0.4 1.8 1 1 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 CCD24444.1 - 1.2e-05 24.8 2.2 3.9e-05 23.1 0.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 CCD24444.1 - 0.0011 18.4 0.1 0.0029 17.0 0.0 1.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 CCD24444.1 - 0.0014 19.1 0.3 0.0033 17.8 0.2 1.9 1 1 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 CCD24444.1 - 0.0025 17.8 0.1 0.0055 16.7 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 CCD24444.1 - 0.0033 17.0 0.1 0.0065 16.0 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCD24444.1 - 0.0033 17.5 0.1 0.012 15.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCD24444.1 - 0.0038 17.1 0.5 0.013 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CCD24444.1 - 0.0043 16.5 0.0 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 CCD24444.1 - 0.0046 16.8 0.0 0.031 14.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 CCD24444.1 - 0.012 15.8 2.7 0.027 14.7 1.8 1.9 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CCD24444.1 - 0.019 14.4 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 CCD24444.1 - 0.02 14.0 1.7 0.27 10.3 1.2 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region IIGP PF05049.8 CCD24444.1 - 0.021 13.6 0.0 0.034 12.9 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) NB-ARC PF00931.17 CCD24444.1 - 0.037 12.8 0.0 0.049 12.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.4 CCD24444.1 - 0.045 13.2 0.4 0.97 8.9 0.1 2.7 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CCD24444.1 - 0.047 13.4 0.1 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 CCD24444.1 - 0.058 12.2 0.3 0.14 11.0 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 CCD24444.1 - 0.062 13.6 2.4 0.11 12.8 1.6 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CCD24444.1 - 0.092 12.0 2.4 1.4 8.1 0.7 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B ArgK PF03308.11 CCD24444.1 - 0.17 10.6 0.5 0.29 9.8 0.0 1.6 2 0 0 2 2 2 0 ArgK protein AAA_17 PF13207.1 CCD24444.1 - 0.23 12.2 1.0 0.77 10.5 0.7 2.2 1 1 0 1 1 1 0 AAA domain Methyltransf_31 PF13847.1 CCD24445.1 - 9.9e-12 44.6 0.1 1.3e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCD24445.1 - 3.6e-08 32.9 0.0 5.8e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CCD24445.1 - 7.5e-08 32.4 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD24445.1 - 2.5e-05 24.8 0.0 4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CCD24445.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 CCD24445.1 - 0.0025 17.4 0.0 0.0034 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.11 CCD24445.1 - 0.0027 16.8 0.0 0.004 16.2 0.0 1.2 1 0 0 1 1 1 1 N-6 DNA Methylase AviRa PF11599.3 CCD24445.1 - 0.02 13.9 0.4 0.028 13.4 0.2 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa Methyltransf_25 PF13649.1 CCD24445.1 - 0.042 14.2 0.0 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.11 CCD24445.1 - 0.055 12.3 0.0 0.092 11.6 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_12 PF08242.7 CCD24445.1 - 0.062 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 CCD24445.1 - 0.078 12.6 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 CCD24445.1 - 0.12 11.6 1.2 4 6.6 0.2 2.6 1 1 2 3 3 3 0 CheR methyltransferase, SAM binding domain Flavodoxin_1 PF00258.20 CCD24446.1 - 3e-08 33.7 0.1 9.3e-08 32.1 0.0 1.8 2 1 0 2 2 2 1 Flavodoxin FMN_red PF03358.10 CCD24446.1 - 5.8e-08 32.3 0.0 9.6e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CCD24446.1 - 0.05 13.0 0.7 0.079 12.4 0.0 1.6 2 0 0 2 2 2 0 Flavodoxin-like fold Daxx PF03344.10 CCD24448.1 - 5.9 5.2 20.5 8.5 4.7 14.2 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 CCD24448.1 - 9.7 5.3 19.0 14 4.8 13.1 1.2 1 0 0 1 1 1 0 SDA1 CN_hydrolase PF00795.17 CCD24449.1 - 9.3e-23 80.5 0.0 1.3e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase GST_N_2 PF13409.1 CCD24450.1 - 2e-17 62.9 0.0 8.7e-17 60.8 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCD24450.1 - 1.5e-09 37.5 0.0 2.8e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCD24450.1 - 0.0021 18.2 0.1 0.45 10.7 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCD24450.1 - 0.01 16.3 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Gsf2 PF11055.3 CCD24451.1 - 4.4e-161 535.6 1.5 5e-161 535.4 1.0 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 CPSF_A PF03178.10 CCD24452.1 - 2.1e-53 181.5 4.2 1e-52 179.2 1.8 2.6 2 0 0 2 2 2 1 CPSF A subunit region Nucleoplasmin PF03066.10 CCD24452.1 - 1.6 8.2 22.4 0.16 11.5 0.3 3.4 3 0 0 3 3 3 0 Nucleoplasmin Suc_Fer-like PF06999.7 CCD24453.1 - 2.2e-34 119.4 0.0 2.9e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like TrbC_Ftype PF09673.5 CCD24453.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein GFO_IDH_MocA PF01408.17 CCD24454.1 - 4.7e-07 30.3 0.0 6.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCD24454.1 - 0.096 12.4 0.0 0.35 10.6 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain SUR7 PF06687.7 CCD24455.1 - 5.7e-36 124.0 12.8 8.1e-36 123.5 8.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 CCD24455.1 - 0.00028 20.8 7.1 0.00042 20.2 4.9 1.2 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF2207 PF09972.4 CCD24455.1 - 1.3 7.5 6.9 1.9 6.9 4.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF805 PF05656.9 CCD24455.1 - 2.9 7.7 11.9 0.51 10.1 5.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Thymidylate_kin PF02223.12 CCD24456.1 - 8.3e-44 149.1 0.1 9.5e-44 148.9 0.1 1.0 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.5 CCD24456.1 - 0.0043 16.3 2.0 0.035 13.2 1.4 2.2 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 CCD24456.1 - 0.025 14.5 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCD24456.1 - 0.11 12.7 2.5 0.11 12.7 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 CCD24456.1 - 0.15 11.9 0.2 0.15 11.9 0.1 2.0 2 1 0 2 2 2 0 AAA domain Clat_adaptor_s PF01217.15 CCD24457.1 - 6.4e-49 165.3 3.6 8.8e-48 161.6 2.5 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AAA PF00004.24 CCD24458.1 - 2.8e-51 173.1 0.0 8.9e-44 148.8 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 CCD24458.1 - 2.6e-20 72.2 0.7 7.3e-20 70.8 0.1 2.1 2 0 0 2 2 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 CCD24458.1 - 9.1e-09 35.5 0.0 0.0054 16.7 0.0 3.4 2 2 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 CCD24458.1 - 7.5e-08 32.3 0.7 0.022 14.6 0.0 3.4 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 CCD24458.1 - 5.7e-07 29.3 0.3 0.053 13.1 0.0 3.9 3 1 0 3 3 3 2 NACHT domain AAA_17 PF13207.1 CCD24458.1 - 6.2e-07 30.2 2.6 0.0089 16.8 0.0 4.1 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.1 CCD24458.1 - 3.8e-05 23.8 3.9 0.22 11.6 0.1 4.6 3 2 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 CCD24458.1 - 5.9e-05 22.8 1.8 0.026 14.2 0.0 3.7 3 1 1 4 4 4 1 Archaeal ATPase AAA_18 PF13238.1 CCD24458.1 - 9.5e-05 22.7 2.5 0.23 11.7 0.0 3.7 3 2 0 3 3 2 2 AAA domain TIP49 PF06068.8 CCD24458.1 - 9.6e-05 21.2 1.0 0.041 12.6 0.0 3.1 3 0 0 3 3 3 1 TIP49 C-terminus AAA_25 PF13481.1 CCD24458.1 - 0.00016 21.1 0.1 0.5 9.7 0.1 3.8 3 1 1 4 4 4 1 AAA domain AAA_19 PF13245.1 CCD24458.1 - 0.00042 20.0 0.0 0.95 9.2 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain RuvB_N PF05496.7 CCD24458.1 - 0.00042 19.4 0.0 0.003 16.6 0.0 2.3 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 CCD24458.1 - 0.00057 18.9 0.0 0.7 8.8 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 CCD24458.1 - 0.00074 19.4 0.0 0.074 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCD24458.1 - 0.0017 18.0 0.0 0.32 10.7 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCD24458.1 - 0.0021 18.0 0.0 0.0076 16.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 CCD24458.1 - 0.0021 18.1 0.0 0.28 11.3 0.0 3.2 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 CCD24458.1 - 0.0023 17.4 0.0 0.076 12.4 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCD24458.1 - 0.0031 16.6 0.0 0.18 10.8 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin Viral_helicase1 PF01443.13 CCD24458.1 - 0.004 16.7 0.0 0.61 9.5 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 CCD24458.1 - 0.015 15.5 0.2 8.1 6.7 0.0 3.5 3 0 0 3 3 3 0 ABC transporter T2SE PF00437.15 CCD24458.1 - 0.031 13.1 0.0 0.75 8.6 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 CCD24458.1 - 0.051 13.2 0.0 7 6.2 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CCD24458.1 - 0.06 13.3 0.0 0.84 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 CCD24458.1 - 0.11 12.1 0.0 0.3 10.7 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CCD24458.1 - 0.12 11.4 0.0 0.55 9.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Pkinase PF00069.20 CCD24459.1 - 8.7e-43 146.3 0.0 1.4e-42 145.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24459.1 - 1.2e-15 57.3 0.0 2e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCD24459.1 - 0.0022 17.0 0.0 0.0038 16.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCD24459.1 - 0.034 13.0 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like ACDC PF14733.1 CCD24459.1 - 0.25 11.5 2.7 5.1 7.2 0.0 3.0 3 0 0 3 3 3 0 AP2-coincident C-terminal APH PF01636.18 CCD24459.1 - 0.26 10.9 0.0 0.41 10.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family LicD PF04991.8 CCD24460.1 - 5.5e-51 173.5 3.2 5.5e-51 173.5 2.2 2.6 2 0 0 2 2 2 1 LicD family FAT PF02259.18 CCD24461.1 - 6.2e-125 416.8 0.0 6.2e-125 416.8 0.0 1.8 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 CCD24461.1 - 5.8e-60 201.8 1.1 6e-59 198.5 0.1 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 CCD24461.1 - 9.4e-60 201.9 0.2 1.8e-59 201.0 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 CCD24461.1 - 3.2e-41 139.4 2.6 1.1e-40 137.7 0.5 3.0 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 CCD24461.1 - 1.2e-16 59.7 0.7 3.5e-16 58.3 0.5 1.9 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 CCD24461.1 - 8e-11 42.0 1.8 0.096 12.9 0.0 8.0 4 1 3 7 7 7 2 HEAT repeats HEAT PF02985.17 CCD24461.1 - 9.3e-08 31.5 3.6 0.015 15.2 0.0 5.9 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 CCD24461.1 - 0.0016 18.9 14.1 0.32 11.5 0.0 9.5 10 1 2 12 12 12 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CCD24461.1 - 0.15 12.5 6.8 3.8 7.9 0.0 5.5 6 1 0 6 6 6 0 Vacuolar 14 Fab1-binding region Xpo1 PF08389.7 CCD24462.1 - 6.9e-35 120.1 0.6 6.9e-35 120.1 0.4 4.3 4 1 1 5 5 5 1 Exportin 1-like protein ATP-gua_PtransN PF02807.10 CCD24462.1 - 0.00019 21.4 0.0 0.0022 18.1 0.0 2.8 3 0 0 3 3 3 1 ATP:guanido phosphotransferase, N-terminal domain Ham1p_like PF01725.11 CCD24463.1 - 3.7e-50 169.9 0.0 4.1e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 Ham1 family HEAT_2 PF13646.1 CCD24464.1 - 9.5e-38 128.3 1.4 5e-19 68.3 0.0 3.3 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 CCD24464.1 - 8.5e-21 72.2 5.2 8.8e-06 25.7 0.0 6.7 7 1 0 7 7 7 3 PBS lyase HEAT-like repeat HEAT PF02985.17 CCD24464.1 - 7.6e-15 53.5 3.3 0.021 14.9 0.0 6.2 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.1 CCD24464.1 - 2e-11 44.0 4.4 0.00071 19.9 0.1 5.1 3 1 2 5 5 5 3 HEAT-like repeat Arm PF00514.18 CCD24464.1 - 0.00099 18.8 0.4 2.5 8.0 0.0 4.1 3 1 1 4 4 4 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 CCD24464.1 - 0.037 12.3 0.3 2.2 6.4 0.0 2.8 2 1 1 3 3 3 0 Adaptin N terminal region ATP_bind_1 PF03029.12 CCD24465.1 - 3.2e-84 282.1 0.2 4.3e-84 281.7 0.2 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CCD24465.1 - 4.8e-07 29.4 1.0 8.1e-06 25.3 0.7 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 CCD24465.1 - 1.8e-06 27.4 0.1 5.4e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain MMR_HSR1 PF01926.18 CCD24465.1 - 4.8e-05 23.2 0.6 0.0009 19.1 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 CCD24465.1 - 5.3e-05 24.0 0.3 0.00095 19.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCD24465.1 - 9.9e-05 22.4 0.0 0.00037 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCD24465.1 - 0.00015 21.6 0.0 0.0003 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 CCD24465.1 - 0.00018 21.0 0.1 0.0084 15.6 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 CCD24465.1 - 0.00046 19.8 0.0 0.00089 18.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_24 PF13479.1 CCD24465.1 - 0.00065 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 CCD24465.1 - 0.0007 18.4 0.0 0.37 9.5 0.0 2.3 2 0 0 2 2 2 2 ArgK protein SRP54 PF00448.17 CCD24465.1 - 0.00073 19.0 0.0 0.039 13.3 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 CCD24465.1 - 0.00074 19.0 0.9 0.0077 15.6 0.6 2.1 1 1 0 1 1 1 1 AAA-like domain AAA_18 PF13238.1 CCD24465.1 - 0.0014 18.9 0.5 0.013 15.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.13 CCD24465.1 - 0.0015 17.8 0.1 0.032 13.5 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.5 CCD24465.1 - 0.0023 17.1 0.4 0.25 10.5 0.0 2.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 CCD24465.1 - 0.0059 16.6 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 CCD24465.1 - 0.012 15.4 2.9 4.6 7.0 0.1 3.2 2 1 0 2 2 2 0 Dynamin family Miro PF08477.8 CCD24465.1 - 0.015 15.8 0.1 1.1 9.7 0.1 2.5 1 1 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 CCD24465.1 - 0.015 14.4 0.1 0.32 10.1 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function, DUF258 FadA PF09403.5 CCD24465.1 - 0.016 15.2 0.6 0.016 15.2 0.4 2.3 1 1 1 2 2 2 0 Adhesion protein FadA MobB PF03205.9 CCD24465.1 - 0.02 14.6 0.1 0.055 13.1 0.0 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 CCD24465.1 - 0.02 14.1 1.6 0.9 8.7 0.0 3.1 3 1 0 3 3 3 0 ADP-ribosylation factor family KTI12 PF08433.5 CCD24465.1 - 0.021 14.0 0.0 0.043 13.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PRK PF00485.13 CCD24465.1 - 0.032 13.7 0.0 0.095 12.2 0.0 1.9 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.12 CCD24465.1 - 0.035 13.9 0.3 4.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 cobW PF02492.14 CCD24465.1 - 0.046 13.1 0.2 0.49 9.8 0.1 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.13 CCD24465.1 - 0.047 12.7 0.1 0.18 10.7 0.1 2.0 1 1 0 1 1 1 0 Septin AAA_30 PF13604.1 CCD24465.1 - 0.05 13.1 0.0 0.083 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain SF3a60_bindingd PF12108.3 CCD24465.1 - 0.069 12.7 0.3 8 6.1 0.0 2.4 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain NB-ARC PF00931.17 CCD24465.1 - 0.081 11.7 0.1 0.17 10.7 0.1 1.5 1 0 0 1 1 1 0 NB-ARC domain Glyco_tranf_2_3 PF13641.1 CCD24465.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 ATP-synt_E PF05680.7 CCD24465.1 - 2 8.4 5.6 0.25 11.3 0.6 1.9 2 0 0 2 2 1 0 ATP synthase E chain DUF106 PF01956.11 CCD24466.1 - 1.2e-55 187.5 1.9 1.5e-55 187.2 1.3 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 ABC_membrane PF00664.18 CCD24468.1 - 1.9e-88 296.4 39.0 6.4e-45 153.7 11.3 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCD24468.1 - 2.4e-64 215.7 0.8 2e-31 109.1 0.0 3.0 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCD24468.1 - 7.9e-16 57.9 10.2 1.8e-06 27.3 0.0 5.0 3 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CCD24468.1 - 2.8e-09 37.2 4.0 0.0038 17.3 0.2 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCD24468.1 - 3.6e-09 36.8 0.3 0.004 17.1 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 CCD24468.1 - 3.4e-08 33.2 1.7 0.0026 17.2 0.1 4.1 4 0 0 4 4 4 2 AAA-like domain AAA_17 PF13207.1 CCD24468.1 - 4.5e-08 33.9 1.1 0.0063 17.3 0.2 3.2 2 1 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 CCD24468.1 - 5.7e-08 31.7 1.0 0.008 14.8 0.0 3.4 4 0 0 4 4 4 2 Predicted ATPase of the ABC class DUF258 PF03193.11 CCD24468.1 - 8.4e-08 31.5 0.4 0.0055 15.9 0.0 2.8 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCD24468.1 - 1.2e-07 31.1 8.4 0.00096 18.6 0.2 3.3 3 0 0 3 3 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.17 CCD24468.1 - 1.8e-07 31.2 0.1 0.0088 16.2 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 CCD24468.1 - 3.5e-06 27.3 3.1 0.044 14.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain MMR_HSR1 PF01926.18 CCD24468.1 - 3.9e-06 26.7 1.6 0.087 12.7 0.1 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF87 PF01935.12 CCD24468.1 - 1.3e-05 25.1 6.3 0.096 12.4 0.0 3.7 4 0 0 4 4 3 2 Domain of unknown function DUF87 AAA_14 PF13173.1 CCD24468.1 - 1.9e-05 24.5 8.8 0.046 13.6 0.0 5.4 5 1 0 6 6 4 1 AAA domain NACHT PF05729.7 CCD24468.1 - 2.3e-05 24.1 1.7 1.9 8.1 0.1 3.6 3 0 0 3 3 3 2 NACHT domain AAA_5 PF07728.9 CCD24468.1 - 2.6e-05 23.9 0.0 0.5 10.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) T2SE PF00437.15 CCD24468.1 - 3.9e-05 22.7 0.8 0.2 10.5 0.1 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein Zeta_toxin PF06414.7 CCD24468.1 - 0.00013 21.1 0.0 0.59 9.1 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin MobB PF03205.9 CCD24468.1 - 0.00023 20.8 0.7 0.5 10.0 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.13 CCD24468.1 - 0.00024 20.2 0.3 0.072 12.0 0.0 2.4 2 0 0 2 2 2 1 Septin AAA_30 PF13604.1 CCD24468.1 - 0.0003 20.4 0.1 0.21 11.1 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 CCD24468.1 - 0.00053 19.8 0.1 0.28 11.0 0.1 2.9 2 1 0 2 2 2 1 AAA domain DUF3987 PF13148.1 CCD24468.1 - 0.00062 18.4 0.0 0.53 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3987) Sigma54_activat PF00158.21 CCD24468.1 - 0.00079 18.9 0.0 0.74 9.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 CCD24468.1 - 0.00095 18.6 0.0 0.45 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CCD24468.1 - 0.0013 18.7 25.1 0.019 14.9 0.3 5.2 4 2 0 4 4 4 2 AAA domain PRK PF00485.13 CCD24468.1 - 0.002 17.7 0.0 0.19 11.2 0.0 2.7 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family APS_kinase PF01583.15 CCD24468.1 - 0.0024 17.5 0.2 2.2 7.9 0.0 2.6 2 0 0 2 2 2 2 Adenylylsulphate kinase Miro PF08477.8 CCD24468.1 - 0.0036 17.7 0.1 6.8 7.2 0.0 3.0 2 0 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 CCD24468.1 - 0.0073 15.8 0.6 9.6 5.6 0.0 3.6 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 CCD24468.1 - 0.0075 15.7 0.0 2.3 7.6 0.0 2.4 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 CCD24468.1 - 0.011 15.2 0.1 3.9 6.8 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 CCD24468.1 - 0.044 13.8 0.0 5.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain MTH865 PF07747.6 CCD24468.1 - 0.047 13.3 0.0 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 MTH865-like family AAA_23 PF13476.1 CCD24468.1 - 0.083 13.2 17.9 0.2 11.9 0.1 3.7 3 1 0 3 3 2 0 AAA domain ArgK PF03308.11 CCD24468.1 - 0.094 11.4 0.1 0.83 8.3 0.0 2.1 2 0 0 2 2 2 0 ArgK protein DPM2 PF07297.7 CCD24469.1 - 6.4e-08 32.7 6.1 6.5e-08 32.7 4.2 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 CCD24469.1 - 0.059 13.0 6.9 0.069 12.7 4.8 1.1 1 0 0 1 1 1 0 PIG-P FtsX PF02687.16 CCD24469.1 - 6 6.6 8.8 7.8 6.2 6.1 1.2 1 0 0 1 1 1 0 FtsX-like permease family Ribosomal_L1 PF00687.16 CCD24470.1 - 1.9e-39 135.2 9.5 1.9e-39 135.2 6.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family ApbA PF02558.11 CCD24471.1 - 3.3e-27 94.7 0.0 5e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 CCD24471.1 - 2.5e-26 92.1 0.0 4.7e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal GCR1_C PF12550.3 CCD24472.1 - 4.9e-08 32.7 3.9 6.5e-08 32.3 0.8 2.3 2 1 1 3 3 3 1 Transcriptional activator of glycolytic enzymes MerR_1 PF13411.1 CCD24472.1 - 0.026 14.2 0.7 0.063 13.0 0.5 1.6 1 0 0 1 1 1 0 MerR HTH family regulatory protein TPR_MLP1_2 PF07926.7 CCD24472.1 - 2.9 7.6 7.6 0.85 9.3 1.0 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 CCD24472.1 - 9.9 5.7 7.0 4.1 6.9 0.8 2.1 2 0 0 2 2 2 0 IncA protein MatE PF01554.13 CCD24473.1 - 1.8e-64 216.2 28.2 5.2e-35 120.4 6.5 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 CCD24473.1 - 5.5e-05 23.0 3.1 5.5e-05 23.0 2.2 3.9 4 0 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Aldo_ket_red PF00248.16 CCD24474.1 - 2e-48 164.6 0.0 2.5e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PIF1 PF05970.9 CCD24475.1 - 2e-51 175.0 3.7 9.5e-49 166.2 2.6 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CCD24475.1 - 4.8e-15 55.6 0.0 8.2e-14 51.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Herpes_Helicase PF02689.9 CCD24475.1 - 3.9e-07 28.2 0.7 0.00023 19.0 0.0 2.3 2 0 0 2 2 2 2 Helicase AAA_22 PF13401.1 CCD24475.1 - 1.6e-05 25.0 1.1 4.5e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CCD24475.1 - 6.6e-05 21.9 2.3 0.00013 20.9 1.6 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 CCD24475.1 - 0.0045 17.1 0.1 0.016 15.3 0.1 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 CCD24475.1 - 0.0079 15.9 0.7 0.018 14.8 0.5 1.5 1 0 0 1 1 1 1 Part of AAA domain LicD PF04991.8 CCD24475.1 - 0.0091 16.1 0.3 0.045 13.8 0.2 2.2 2 0 0 2 2 2 1 LicD family DUF2075 PF09848.4 CCD24475.1 - 0.011 14.7 0.2 0.029 13.3 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 CCD24475.1 - 0.017 14.3 0.0 0.04 13.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.1 CCD24475.1 - 0.018 15.1 0.0 0.18 11.9 0.0 2.4 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.16 CCD24475.1 - 0.031 13.4 0.1 0.066 12.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Helicase_RecD PF05127.9 CCD24475.1 - 0.031 13.9 0.5 0.14 11.8 0.3 2.1 1 1 0 1 1 1 0 Helicase RNA_helicase PF00910.17 CCD24475.1 - 0.21 11.7 1.4 1.4 9.1 0.2 2.9 2 1 0 2 2 2 0 RNA helicase Pkinase PF00069.20 CCD24476.1 - 1.5e-68 230.7 0.4 3.5e-68 229.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24476.1 - 1.1e-30 106.6 0.6 1.8e-30 105.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCD24476.1 - 0.01 15.5 2.2 0.1 12.2 0.1 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family LIM_bind PF01803.11 CCD24476.1 - 0.19 10.8 7.3 0.31 10.1 5.1 1.2 1 0 0 1 1 1 0 LIM-domain binding protein DUF4230 PF14014.1 CCD24476.1 - 0.29 10.9 6.4 0.68 9.7 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4230) NABP PF07990.7 CCD24476.1 - 1.1 8.4 8.5 1.5 7.9 5.9 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Med15 PF09606.5 CCD24476.1 - 2.1 6.4 24.2 2.7 6.0 16.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal UPF0560 PF10577.4 CCD24476.1 - 2.9 6.0 11.7 4.1 5.5 8.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PhzC-PhzF PF02567.11 CCD24477.1 - 1.6e-66 224.3 0.0 1.9e-66 224.1 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Elf1 PF05129.8 CCD24478.1 - 2.3e-30 104.0 1.5 3e-30 103.7 1.1 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.14 CCD24478.1 - 0.0064 16.3 1.6 0.011 15.6 1.1 1.3 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-C2H2_2 PF12756.2 CCD24478.1 - 0.3 11.2 3.3 1.8 8.6 0.3 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-Sec23_Sec24 PF04810.10 CCD24478.1 - 0.94 9.0 6.5 2.6 7.6 1.2 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger COX5A PF02284.11 CCD24479.1 - 1.3e-51 173.1 1.3 1.6e-51 172.8 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va DIOX_N PF14226.1 CCD24479.1 - 0.092 13.2 1.0 0.95 10.0 0.1 2.2 1 1 1 2 2 2 0 non-haem dioxygenase in morphine synthesis N-terminal Nramp PF01566.13 CCD24480.1 - 1.4e-93 313.5 12.3 2e-93 313.0 8.5 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Mg296 PF09644.5 CCD24480.1 - 0.73 9.6 3.3 0.37 10.6 0.7 1.7 2 0 0 2 2 2 0 Mg296 protein FSH1 PF03959.8 CCD24481.1 - 1.5e-62 210.7 0.0 1.7e-62 210.5 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CCD24481.1 - 4.6e-05 23.1 0.0 6.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCD24481.1 - 0.0077 16.1 0.0 2.7 7.7 0.0 2.4 1 1 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCD24481.1 - 0.012 15.0 0.4 0.48 9.8 0.2 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2305 PF10230.4 CCD24481.1 - 0.03 13.7 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Abhydrolase_1 PF00561.15 CCD24481.1 - 0.12 11.8 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold MFS_1 PF07690.11 CCD24482.1 - 1.1e-34 119.7 32.7 1.1e-34 119.7 22.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCD24482.1 - 1.3e-05 23.9 40.1 3.3e-05 22.6 27.8 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter Inositol_P PF00459.20 CCD24483.1 - 9.1e-68 228.4 0.0 1e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF1953 PF09196.5 CCD24483.1 - 0.012 15.3 0.8 0.024 14.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1953) PBD PF00786.23 CCD24485.1 - 0.0054 17.1 0.1 0.0054 17.1 0.1 3.2 5 0 0 5 5 5 1 P21-Rho-binding domain Glyco_hydro_42 PF02449.10 CCD24486.1 - 0.0089 15.1 0.0 0.011 14.8 0.0 1.1 1 0 0 1 1 1 1 Beta-galactosidase RRN3 PF05327.6 CCD24486.1 - 0.048 11.7 1.0 0.065 11.3 0.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TFIIE-A_C-term PF11521.3 CCD24486.1 - 0.055 13.4 3.5 0.084 12.8 1.2 2.1 2 0 0 2 2 2 0 C-terminal general transcription factor TFIIE alpha DUF2722 PF10846.3 CCD24486.1 - 0.16 10.9 3.8 0.21 10.5 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) HSP70 PF00012.15 CCD24486.1 - 0.67 7.7 7.4 0.95 7.2 5.1 1.1 1 0 0 1 1 1 0 Hsp70 protein CDC45 PF02724.9 CCD24486.1 - 0.77 7.7 7.1 1.1 7.2 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein IGR PF09597.5 CCD24487.1 - 4.3e-25 87.3 0.2 6.9e-25 86.7 0.1 1.3 1 0 0 1 1 1 1 IGR protein motif SAM_2 PF07647.12 CCD24487.1 - 0.0046 16.7 0.0 0.0084 15.9 0.0 1.4 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) Med6 PF04934.9 CCD24488.1 - 5.8e-55 184.6 0.1 8.4e-55 184.1 0.1 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Med10 PF09748.4 CCD24488.1 - 0.046 13.5 1.1 0.081 12.7 0.1 1.8 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex CoA_trans PF01144.18 CCD24488.1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase MFS_1 PF07690.11 CCD24489.1 - 1.6e-31 109.2 23.3 1.6e-31 109.2 16.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 CCD24489.1 - 0.07 13.5 0.1 0.2 12.0 0.0 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) BrkDBD PF09607.5 CCD24489.1 - 0.085 12.4 0.2 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Brinker DNA-binding domain zf-DHHC PF01529.15 CCD24489.1 - 0.62 9.4 8.8 99 2.2 5.1 3.0 1 1 0 1 1 1 0 DHHC palmitoyltransferase Pro_isomerase PF00160.16 CCD24490.1 - 2.5e-42 144.7 0.2 3e-42 144.4 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Zn_clus PF00172.13 CCD24491.1 - 1.2e-07 31.5 7.2 1.8e-07 30.9 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PC_rep PF01851.17 CCD24493.1 - 1.5e-25 87.9 11.9 4.5e-06 26.5 0.1 9.1 9 0 0 9 9 9 5 Proteasome/cyclosome repeat Mem_trans PF03547.13 CCD24493.1 - 0.005 15.1 0.1 0.024 12.9 0.0 1.9 2 0 0 2 2 2 1 Membrane transport protein ATP-synt_C PF00137.16 CCD24494.1 - 2.4e-28 97.8 26.2 2.1e-18 65.9 6.3 2.4 2 0 0 2 2 2 2 ATP synthase subunit C 2TM PF13239.1 CCD24494.1 - 2.8 8.0 8.5 0.16 12.0 0.7 2.4 2 1 0 2 2 2 0 2TM domain GHMP_kinases_N PF00288.21 CCD24495.1 - 5.8e-12 45.4 0.0 1.1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCD24495.1 - 0.00025 21.2 0.0 0.00063 19.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M16 PF00675.15 CCD24496.1 - 6.8e-42 142.7 0.0 3.2e-41 140.5 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCD24496.1 - 7.8e-42 143.0 0.0 3.1e-41 141.0 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain AAA_5 PF07728.9 CCD24496.1 - 0.013 15.1 0.0 0.035 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Myosin_head PF00063.16 CCD24497.1 - 1.4e-256 852.9 12.3 1.4e-256 852.9 8.5 3.5 3 1 1 4 4 4 1 Myosin head (motor domain) Tox-HDC PF15656.1 CCD24497.1 - 0.039 14.1 4.5 0.059 13.5 0.9 3.1 2 0 0 2 2 2 0 Toxin with a H, D/N and C signature AAA_19 PF13245.1 CCD24497.1 - 0.43 10.3 0.0 0.95 9.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Ras PF00071.17 CCD24498.1 - 7.1e-26 90.5 0.9 6.4e-18 64.6 0.2 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CCD24498.1 - 5.8e-18 65.5 0.1 7.1e-11 42.6 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 CCD24498.1 - 1.5e-06 27.8 1.2 7.2e-05 22.3 0.8 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCD24498.1 - 0.0017 17.5 0.2 0.023 13.8 0.3 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CCD24498.1 - 0.087 12.3 0.0 1.6 8.2 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation HCV_NS5a_C PF12941.2 CCD24498.1 - 0.88 9.0 4.1 0.26 10.8 0.2 1.8 2 0 0 2 2 2 0 HCV NS5a protein C-terminal region Ribosomal_S27e PF01667.12 CCD24499.1 - 2.1e-30 104.0 2.7 2.9e-30 103.5 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CCD24499.1 - 2.7e-05 23.9 0.7 3.3e-05 23.6 0.5 1.1 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 CCD24499.1 - 0.051 12.8 3.8 0.074 12.3 2.6 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 CCD24499.1 - 0.13 11.8 1.3 6.2 6.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CCD24499.1 - 0.14 11.8 1.3 6.3 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain NIF PF03031.13 CCD24500.1 - 6.7e-52 175.3 0.1 2.1e-51 173.7 0.0 1.9 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Abhydro_lipase PF04083.11 CCD24501.1 - 5.8e-17 60.7 0.0 1.1e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CCD24501.1 - 0.00038 20.3 0.0 0.00047 20.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 CCD24501.1 - 0.0095 15.2 0.1 0.024 13.9 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 CCD24501.1 - 0.0097 15.4 0.0 0.29 10.6 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold PUF PF00806.14 CCD24502.1 - 9.6e-54 175.9 19.1 4.5e-07 28.9 0.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Rab5ip PF07019.7 CCD24503.1 - 8.7e-17 61.0 6.5 1.1e-16 60.7 4.5 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) MARVEL PF01284.18 CCD24503.1 - 0.58 9.9 8.7 0.061 13.1 1.7 1.9 1 1 0 2 2 2 0 Membrane-associating domain 2TM PF13239.1 CCD24503.1 - 0.68 10.0 2.8 1.1 9.3 1.9 1.4 1 1 0 1 1 1 0 2TM domain DUF383 PF04063.9 CCD24504.1 - 3.7e-70 235.3 0.7 3.7e-70 235.3 0.5 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 CCD24504.1 - 1.8e-23 81.8 0.2 6.3e-23 80.1 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Med8 PF10232.4 CCD24504.1 - 0.0011 18.4 0.1 0.0026 17.2 0.1 1.5 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Med17 PF10156.4 CCD24504.1 - 0.0078 14.5 1.7 0.011 14.0 1.2 1.2 1 0 0 1 1 1 1 Subunit 17 of Mediator complex HEAT_2 PF13646.1 CCD24504.1 - 0.095 12.9 0.0 1.4 9.2 0.0 2.8 3 1 0 3 3 3 0 HEAT repeats DUF4611 PF15387.1 CCD24504.1 - 1.7 8.8 10.2 4.8 7.4 7.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) NOA36 PF06524.7 CCD24504.1 - 1.9 7.7 6.1 2.6 7.2 4.3 1.2 1 0 0 1 1 1 0 NOA36 protein Bd3614_N PF14442.1 CCD24504.1 - 2.6 8.0 5.1 4 7.4 3.5 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Nucleoplasmin PF03066.10 CCD24504.1 - 9.7 5.6 12.6 22 4.5 8.7 1.6 1 0 0 1 1 1 0 Nucleoplasmin TFIIF_alpha PF05793.7 CCD24505.1 - 1.9e-05 23.2 43.6 1.9e-05 23.2 30.3 3.3 2 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-UBR PF02207.15 CCD24506.1 - 1.4e-16 59.9 15.4 1.4e-16 59.9 10.7 2.4 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CCD24506.1 - 4.1e-08 32.8 0.0 9.3e-08 31.6 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 CCD24506.1 - 0.0014 18.4 1.4 0.0014 18.4 1.0 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 CCD24506.1 - 0.0024 17.4 1.5 0.012 15.3 1.0 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD24506.1 - 0.0033 17.4 1.7 0.0033 17.4 1.2 2.8 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) UCR_UQCRX_QCR9 PF05365.7 CCD24507.1 - 8.3e-27 92.5 3.0 9.2e-27 92.4 2.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2976 PF11190.3 CCD24507.1 - 0.043 13.3 0.1 0.047 13.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2976) zf-Tim10_DDP PF02953.10 CCD24508.1 - 1.2e-17 62.8 2.9 1.9e-17 62.3 2.0 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribonuc_red_sm PF00268.16 CCD24509.1 - 3.2e-76 256.0 0.8 4.3e-76 255.5 0.5 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain E3_UbLigase_R4 PF13764.1 CCD24509.1 - 0.028 12.3 0.5 0.062 11.1 0.1 1.7 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase UBR4 Hom_end_hint PF05203.11 CCD24509.1 - 0.16 11.7 1.7 0.21 11.3 0.6 1.5 2 0 0 2 2 2 0 Hom_end-associated Hint LsmAD PF06741.8 CCD24511.1 - 1.7e-29 101.6 0.4 6.7e-29 99.8 0.3 2.1 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 CCD24511.1 - 3.6e-16 58.8 0.4 3.6e-16 58.8 0.2 2.3 2 0 0 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.2 CCD24511.1 - 0.00073 19.2 0.7 0.002 17.9 0.1 2.0 2 0 0 2 2 2 1 Scd6-like Sm domain AATase PF07247.7 CCD24512.1 - 8.4e-132 440.1 6.1 9.6e-132 439.9 4.2 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 CCD24512.1 - 0.00078 18.3 0.1 0.79 8.5 0.0 3.0 3 0 0 3 3 3 2 Condensation domain DUF1256 PF06866.6 CCD24512.1 - 0.057 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) SE PF08491.5 CCD24513.1 - 1.3e-116 388.2 0.0 1.7e-116 387.8 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 CCD24513.1 - 8.7e-14 51.3 0.0 1.5e-13 50.5 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCD24513.1 - 4.1e-08 32.5 0.1 1.1e-05 24.5 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCD24513.1 - 0.0002 21.6 0.1 0.00071 19.9 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCD24513.1 - 0.00041 20.3 0.1 0.001 19.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 CCD24513.1 - 0.0015 18.4 0.2 0.0036 17.2 0.0 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCD24513.1 - 0.0021 17.1 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 CCD24513.1 - 0.003 17.2 0.2 0.0047 16.5 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 CCD24513.1 - 0.0033 17.5 0.0 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 CCD24513.1 - 0.0054 15.6 1.8 0.0084 14.9 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 CCD24513.1 - 0.0081 15.2 0.2 0.031 13.3 0.3 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase DUF1331 PF07048.6 CCD24513.1 - 0.02 14.3 0.6 0.066 12.6 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) Lycopene_cycl PF05834.7 CCD24513.1 - 0.036 12.9 0.2 2.4 6.9 0.2 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein ApbA PF02558.11 CCD24513.1 - 0.036 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDI PF00996.13 CCD24513.1 - 0.04 12.2 0.0 0.06 11.6 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor CABIT PF12736.2 CCD24513.1 - 0.054 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Cell-cycle sustaining, positive selection, NAD_Gly3P_dh_N PF01210.18 CCD24513.1 - 0.13 12.0 0.1 0.26 11.0 0.0 1.5 2 0 0 2 2 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 CCD24513.1 - 0.14 11.4 0.2 0.54 9.6 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain CBP4 PF07960.6 CCD24514.1 - 1.5e-48 163.6 3.7 1.7e-48 163.4 2.5 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.1 CCD24514.1 - 0.014 15.1 1.4 0.028 14.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4574) Strep_SA_rep PF06696.6 CCD24514.1 - 0.18 11.6 0.6 0.18 11.6 0.4 3.3 4 0 0 4 4 4 0 Streptococcal surface antigen repeat LAMTOR PF15454.1 CCD24514.1 - 0.74 10.1 4.2 0.29 11.4 0.5 1.9 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator MMR_HSR1 PF01926.18 CCD24515.1 - 7.2e-20 71.0 0.3 2.1e-19 69.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 CCD24515.1 - 1.9e-19 69.2 0.0 3.9e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CCD24515.1 - 1.8e-13 50.0 0.0 3e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCD24515.1 - 3.1e-05 23.8 0.4 0.017 14.9 0.0 2.4 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 CCD24515.1 - 0.00026 21.4 0.1 0.00089 19.7 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 CCD24515.1 - 0.00052 19.1 0.0 0.00092 18.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 CCD24515.1 - 0.01 15.0 0.3 0.081 12.1 0.0 2.2 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MCM PF00493.18 CCD24515.1 - 0.015 14.1 0.0 0.027 13.2 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family Ras PF00071.17 CCD24515.1 - 0.027 13.8 0.3 0.71 9.2 0.0 2.3 2 0 0 2 2 2 0 Ras family Yip1 PF04893.12 CCD24516.1 - 1.2e-12 47.6 14.3 1.7e-12 47.1 9.9 1.2 1 0 0 1 1 1 1 Yip1 domain DER1 PF04511.10 CCD24516.1 - 0.018 14.5 4.2 0.026 14.0 2.9 1.2 1 0 0 1 1 1 0 Der1-like family tRNA-synt_1g PF09334.6 CCD24517.1 - 1.4e-105 353.1 2.3 2.7e-105 352.2 1.6 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CCD24517.1 - 4.4e-27 94.3 1.6 3.4e-13 48.4 0.1 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CCD24517.1 - 1.7e-07 30.7 0.1 0.0014 17.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain PS_Dcarbxylase PF02666.10 CCD24518.1 - 7.5e-51 172.3 0.0 1.2e-50 171.5 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 CCD24518.1 - 1.8e-17 62.9 0.6 1.4e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 C2 domain RRM PF10378.4 CCD24518.1 - 0.0017 17.9 2.5 0.0039 16.7 1.8 1.6 1 0 0 1 1 1 1 Putative RRM domain IFT20 PF14931.1 CCD24519.1 - 0.93 9.4 16.1 1.2 9.0 11.2 1.1 1 0 0 1 1 1 0 Intraflagellar transport complex B, subunit 20 DUF1764 PF08576.5 CCD24519.1 - 1 10.1 13.1 1.3 9.8 9.1 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) AIF_C PF14721.1 CCD24519.1 - 3.8 7.7 6.9 4.8 7.4 4.8 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Tom37_C PF11801.3 CCD24519.1 - 4.7 7.0 11.0 5.4 6.8 7.6 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain FCSD-flav_bind PF09242.6 CCD24519.1 - 4.8 7.2 5.3 1.9 8.5 1.8 1.7 1 1 1 2 2 2 0 Flavocytochrome c sulphide dehydrogenase, flavin-binding DUF4355 PF14265.1 CCD24519.1 - 5 7.0 28.3 6.9 6.6 19.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) PseudoU_synth_2 PF00849.17 CCD24520.1 - 1.1e-26 93.6 0.0 1.8e-26 92.9 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase ATP_synt_H PF05493.8 CCD24521.1 - 1.9e-21 75.8 3.6 2.3e-21 75.6 2.5 1.1 1 0 0 1 1 1 1 ATP synthase subunit H Cyt_c_ox_IV PF12270.3 CCD24521.1 - 0.011 15.4 0.6 0.013 15.2 0.4 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Ilm1 PF10311.4 CCD24521.1 - 0.013 15.0 0.9 0.014 14.9 0.6 1.0 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 7TM-7TMR_HD PF07698.6 CCD24521.1 - 0.018 14.4 1.9 0.021 14.2 1.3 1.1 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Na_Ca_ex PF01699.19 CCD24521.1 - 0.032 13.8 0.9 0.033 13.7 0.6 1.1 1 0 0 1 1 1 0 Sodium/calcium exchanger protein YibE_F PF07907.6 CCD24521.1 - 0.056 12.6 1.4 0.062 12.4 1.0 1.1 1 0 0 1 1 1 0 YibE/F-like protein MgtE PF01769.11 CCD24521.1 - 0.064 13.5 0.8 0.066 13.4 0.5 1.0 1 0 0 1 1 1 0 Divalent cation transporter AzlD PF05437.7 CCD24521.1 - 0.085 12.8 2.8 0.14 12.1 0.1 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) DUF4401 PF14351.1 CCD24521.1 - 0.091 11.7 3.9 0.096 11.6 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Renin_r PF07850.9 CCD24521.1 - 0.12 12.6 0.7 0.16 12.3 0.2 1.4 1 1 0 1 1 1 0 Renin receptor-like protein DUF4271 PF14093.1 CCD24521.1 - 0.47 10.1 4.4 0.53 9.9 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) TMEM192 PF14802.1 CCD24521.1 - 0.5 9.1 2.7 0.52 9.1 1.8 1.0 1 0 0 1 1 1 0 TMEM192 family DUF2231 PF09990.4 CCD24521.1 - 0.92 9.8 5.5 1.1 9.6 3.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF3624 PF12292.3 CCD24521.1 - 1.1 9.7 3.7 1.6 9.1 2.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3624) CitMHS PF03600.11 CCD24521.1 - 1.2 7.6 5.6 1.2 7.5 3.9 1.0 1 0 0 1 1 1 0 Citrate transporter DUF1129 PF06570.6 CCD24521.1 - 2.2 7.5 5.3 3.4 6.9 3.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1129) Yip1 PF04893.12 CCD24521.1 - 3.2 7.2 7.6 4.6 6.7 5.2 1.3 1 1 0 1 1 1 0 Yip1 domain FixQ PF05545.6 CCD24521.1 - 4.3 7.0 8.2 0.58 9.8 1.6 2.1 1 1 1 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF2405 PF10293.4 CCD24522.1 - 0.87 9.3 4.1 2.8 7.6 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2405) Clathrin_lg_ch PF01086.12 CCD24523.1 - 9.9e-54 182.6 22.4 1.9e-53 181.6 15.5 1.4 1 1 0 1 1 1 1 Clathrin light chain Bcl-2 PF00452.14 CCD24523.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family Trs65 PF12735.2 CCD24524.1 - 6.2e-43 147.2 13.1 6.2e-43 147.2 9.1 1.8 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 Bot1p PF12298.3 CCD24525.1 - 4.8e-58 195.8 0.6 6.6e-58 195.4 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein DUF2316 PF10078.4 CCD24525.1 - 0.00034 20.5 0.1 0.001 19.0 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2316) HTH_37 PF13744.1 CCD24525.1 - 0.035 13.9 0.3 0.091 12.5 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Sad1_UNC PF07738.8 CCD24526.1 - 1.8e-09 37.5 0.2 1.3e-07 31.4 0.2 2.4 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal SF-assemblin PF06705.6 CCD24526.1 - 0.21 10.6 4.7 0.12 11.4 1.2 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin Baculo_PEP_C PF04513.7 CCD24526.1 - 3.9 7.2 17.8 0.1 12.4 1.6 4.0 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cpn60_TCP1 PF00118.19 CCD24527.1 - 4.9e-155 516.8 2.2 5.6e-155 516.6 1.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mad3_BUB1_I PF08311.7 CCD24528.1 - 5.8e-25 87.5 2.8 1.4e-24 86.2 2.0 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 CCD24528.1 - 3e-22 78.2 1.3 8.8e-22 76.7 0.9 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase PF00069.20 CCD24528.1 - 2.3e-20 72.8 0.0 5e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24528.1 - 9.2e-06 24.9 0.0 2.3e-05 23.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase DUF2782 PF11191.3 CCD24528.1 - 0.0044 16.9 1.5 0.016 15.1 0.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2782) Hexokinase_2 PF03727.11 CCD24528.1 - 0.006 15.8 0.1 0.029 13.5 0.0 2.0 2 0 0 2 2 2 1 Hexokinase Kinase-like PF14531.1 CCD24528.1 - 0.026 13.4 0.0 0.051 12.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Glyco_hydro_16 PF00722.16 CCD24529.1 - 1.1e-46 158.4 1.3 1.1e-46 158.4 0.9 2.8 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 AA_permease PF00324.16 CCD24530.1 - 2.6e-135 451.4 34.6 3.2e-135 451.1 24.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD24530.1 - 3.3e-40 137.9 37.0 4.1e-40 137.6 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease CobD_Cbib PF03186.8 CCD24530.1 - 0.0012 17.9 0.0 0.0045 16.1 0.0 2.0 1 1 0 1 1 1 1 CobD/Cbib protein Gp_dh_C PF02800.15 CCD24531.1 - 6.6e-74 246.5 0.1 1e-73 245.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CCD24531.1 - 1.1e-58 197.5 0.9 5.6e-58 195.2 0.1 2.0 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Biotin_lipoyl PF00364.17 CCD24532.1 - 5.3e-21 74.0 0.4 1.4e-20 72.6 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CCD24532.1 - 9.9e-05 21.9 0.0 0.00024 20.6 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 CCD24532.1 - 0.00078 19.0 1.8 0.054 13.1 0.0 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like DUF3888 PF13027.1 CCD24532.1 - 0.051 13.4 0.3 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3888) QRPTase_N PF02749.11 CCD24532.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain FGGY_N PF00370.16 CCD24533.1 - 9.7e-24 84.0 0.0 2.1e-13 50.1 0.0 2.4 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CCD24533.1 - 8.1e-12 45.1 0.0 6.2e-11 42.2 0.0 2.4 2 1 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain AroM PF07302.6 CCD24533.1 - 0.18 11.0 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 AroM protein DUF3533 PF12051.3 CCD24535.1 - 5.9e-131 436.7 26.3 7.3e-131 436.4 18.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) TPR_16 PF13432.1 CCD24536.1 - 0.0032 18.0 0.1 0.78 10.4 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCD24536.1 - 0.0086 16.1 5.5 1.4 9.3 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCD24536.1 - 0.049 13.2 17.4 0.3 10.7 0.2 5.3 6 0 0 6 6 6 0 TPR repeat TPR_8 PF13181.1 CCD24536.1 - 0.24 11.2 11.0 2.6 8.0 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat YgbB PF02542.11 CCD24536.1 - 0.35 10.6 2.4 0.51 10.1 0.2 2.4 3 0 0 3 3 3 0 YgbB family DUF3533 PF12051.3 CCD24537.1 - 4.8e-116 387.6 18.6 6.1e-116 387.2 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.7 CCD24537.1 - 0.08 12.6 0.0 0.08 12.6 0.0 3.4 4 0 0 4 4 4 0 CDR ABC transporter PMT PF02366.13 CCD24538.1 - 2.6e-84 282.4 21.6 2.6e-84 282.4 15.0 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCD24538.1 - 3.1e-23 82.2 1.1 5.6e-23 81.4 0.7 1.4 1 0 0 1 1 1 1 MIR domain WD40 PF00400.27 CCD24539.1 - 2.4e-55 182.5 27.9 3.7e-10 39.2 0.1 11.8 13 0 0 13 13 13 9 WD domain, G-beta repeat Rhodanese PF00581.15 CCD24540.1 - 5.4e-11 42.8 0.0 7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain FTHFS PF01268.14 CCD24541.1 - 3.4e-256 850.6 0.4 5.1e-256 850.0 0.3 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CCD24541.1 - 2.6e-62 208.6 0.3 6.8e-62 207.2 0.2 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CCD24541.1 - 3.7e-38 130.1 0.8 8.3e-38 129.0 0.6 1.6 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GTP_EFTU PF00009.22 CCD24541.1 - 0.021 14.2 0.0 0.062 12.7 0.0 1.8 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AdoHcyase_NAD PF00670.16 CCD24541.1 - 0.045 13.5 3.9 0.49 10.2 0.2 3.0 3 1 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AAA_17 PF13207.1 CCD24542.1 - 0.0002 22.1 0.3 0.00046 20.9 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCD24542.1 - 0.004 17.4 0.2 0.016 15.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain Torsin PF06309.6 CCD24542.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_14 PF13173.1 CCD24542.1 - 0.012 15.5 0.0 0.027 14.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCD24542.1 - 0.012 15.7 0.0 0.029 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 CCD24542.1 - 0.064 12.3 0.0 0.095 11.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Mvb12 PF09452.5 CCD24543.1 - 6.7e-35 119.1 0.5 8e-35 118.8 0.4 1.1 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 ETF PF01012.16 CCD24544.1 - 1.5e-29 102.8 0.0 2.1e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain HAD PF12710.2 CCD24545.1 - 3.9e-13 50.0 0.2 5.1e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCD24545.1 - 4.1e-11 43.7 0.1 9.7e-10 39.2 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCD24545.1 - 1.9e-10 40.7 1.1 1.5e-08 34.5 0.0 3.0 2 2 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCD24545.1 - 0.008 16.4 0.1 0.039 14.1 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase S6PP PF05116.8 CCD24545.1 - 0.042 13.1 0.1 0.33 10.2 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Peptidase_C34 PF05413.6 CCD24545.1 - 0.066 13.2 0.3 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Putative closterovirus papain-like endopeptidase Thioredoxin PF00085.15 CCD24546.1 - 5.3e-32 109.6 0.6 5.8e-32 109.4 0.4 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCD24546.1 - 6.3e-10 39.2 0.2 1.3e-08 34.9 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CCD24546.1 - 5.1e-09 35.7 0.3 5.9e-09 35.5 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CCD24546.1 - 1.2e-07 31.7 0.1 4.8e-07 29.7 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 CCD24546.1 - 6.3e-05 22.6 0.1 7.6e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCD24546.1 - 0.0003 20.3 0.2 0.0004 19.9 0.1 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 CCD24546.1 - 0.0014 18.5 0.4 0.0035 17.3 0.3 1.6 1 1 0 1 1 1 1 Thioredoxin-like DIM1 PF02966.11 CCD24546.1 - 0.002 17.6 0.1 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin_3 PF13192.1 CCD24546.1 - 0.0092 15.7 0.1 0.014 15.2 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.1 CCD24546.1 - 0.012 15.6 0.6 3.2 7.7 0.0 2.3 1 1 1 2 2 2 0 Thioredoxin TraF PF13728.1 CCD24546.1 - 0.023 14.1 0.1 0.035 13.6 0.1 1.3 1 1 0 1 1 1 0 F plasmid transfer operon protein HyaE PF07449.6 CCD24546.1 - 0.072 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Phosducin PF02114.11 CCD24546.1 - 0.074 11.7 0.0 0.081 11.6 0.0 1.0 1 0 0 1 1 1 0 Phosducin DSBA PF01323.15 CCD24546.1 - 0.084 12.4 0.4 0.22 11.0 0.1 1.7 1 1 1 2 2 2 0 DSBA-like thioredoxin domain MMR_HSR1_C PF08438.5 CCD24547.1 - 1.4e-32 112.1 0.1 2.4e-32 111.3 0.0 1.4 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 CCD24547.1 - 6.9e-18 64.6 0.0 1.5e-17 63.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCD24547.1 - 1.5e-07 30.8 0.1 3.3e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CCD24547.1 - 0.00077 18.9 0.1 0.44 9.9 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCD24547.1 - 0.0019 18.0 0.7 0.011 15.6 0.1 2.4 2 2 1 4 4 4 1 Dynamin family ATP_bind_1 PF03029.12 CCD24547.1 - 0.0034 16.9 0.1 2.6 7.5 0.0 2.2 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CCD24547.1 - 0.0091 15.4 0.0 0.029 13.8 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 CCD24547.1 - 0.017 13.9 0.2 0.18 10.5 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_17 PF13207.1 CCD24547.1 - 0.035 14.9 0.7 0.1 13.4 0.1 2.2 2 1 0 2 2 1 0 AAA domain AAA_29 PF13555.1 CCD24547.1 - 0.1 12.1 0.2 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain KTI12 PF08433.5 CCD24547.1 - 0.1 11.7 0.0 0.25 10.5 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 cobW PF02492.14 CCD24547.1 - 0.11 11.9 0.0 2.4 7.5 0.0 2.6 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 CCD24547.1 - 0.11 12.7 0.0 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter RSF PF14876.1 CCD24548.1 - 1.5e-13 50.3 6.2 1.5e-13 50.3 4.3 2.4 1 1 1 2 2 2 1 Respiratory growth transcriptional regulator zf-ZPR1 PF03367.8 CCD24549.1 - 2.5e-118 390.8 4.4 4.1e-59 198.3 0.1 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain UPF0547 PF10571.4 CCD24549.1 - 0.093 12.4 9.1 0.74 9.5 0.1 3.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 Thymopoietin PF08198.6 CCD24549.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.6 1 0 0 1 1 1 0 Thymopoietin protein Lar_restr_allev PF14354.1 CCD24549.1 - 2.2 8.6 9.3 13 6.1 0.1 3.5 3 1 0 3 3 3 0 Restriction alleviation protein Lar Elf1 PF05129.8 CCD24549.1 - 2.3 7.9 6.8 4 7.2 0.1 3.2 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 CCD24549.1 - 7.4 6.4 7.2 9.9 6.0 0.0 3.3 4 0 0 4 4 4 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 CCD24549.1 - 7.9 6.1 15.0 1.6 8.3 0.6 4.3 4 0 0 4 4 4 0 zinc-ribbon domain AATase PF07247.7 CCD24550.1 - 3.1e-74 250.2 6.2 3.9e-74 249.9 4.3 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 CCD24550.1 - 4.2e-07 29.1 0.4 1.1e-05 24.4 0.1 2.0 2 0 0 2 2 2 2 Condensation domain WES_acyltransf PF03007.11 CCD24550.1 - 0.0062 16.1 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Wax ester synthase-like Acyl-CoA acyltransferase domain RTA1 PF04479.8 CCD24551.1 - 8.1e-84 280.6 11.5 8.1e-84 280.6 8.0 1.8 2 0 0 2 2 2 1 RTA1 like protein DUF373 PF04123.8 CCD24551.1 - 2.4 7.1 10.2 0.87 8.5 2.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Ribosomal_S2 PF00318.15 CCD24552.1 - 8e-40 136.3 0.0 1.1e-20 73.7 0.0 2.6 2 1 1 3 3 3 2 Ribosomal protein S2 MRP-S33 PF08293.6 CCD24553.1 - 1.7e-33 114.4 0.1 2.3e-33 114.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Gpi1 PF05024.10 CCD24554.1 - 9.9e-54 181.8 17.8 2.5e-53 180.5 12.3 1.7 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) Ion_trans PF00520.26 CCD24555.1 - 3.2e-88 294.2 104.1 2.4e-31 108.5 5.7 5.7 5 1 0 5 5 5 4 Ion transport protein EF-hand_1 PF00036.27 CCD24555.1 - 0.017 14.4 0.0 0.072 12.4 0.0 2.2 2 0 0 2 2 2 0 EF hand CRM1_C PF08767.6 CCD24556.1 - 2.4e-132 440.7 2.4 2.4e-132 440.7 1.6 2.8 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 CCD24556.1 - 5.7e-37 126.9 6.5 5.7e-37 126.9 4.5 4.1 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 CCD24556.1 - 7.9e-14 51.3 2.0 1.4e-13 50.5 0.2 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF507 PF04368.8 CCD24556.1 - 0.00022 20.9 1.0 0.33 10.5 0.2 2.8 2 0 0 2 2 2 2 Protein of unknown function (DUF507) Ribosomal_L3 PF00297.17 CCD24557.1 - 4.4e-41 141.0 1.1 1.4e-38 132.8 0.3 2.0 1 1 1 2 2 2 2 Ribosomal protein L3 PuR_N PF09182.5 CCD24558.1 - 0.36 10.4 4.4 2.8 7.6 0.0 3.3 3 0 0 3 3 3 0 Bacterial purine repressor, N-terminal Smg4_UPF3 PF03467.10 CCD24559.1 - 0.017 15.0 0.2 0.017 15.0 0.1 2.8 2 1 0 2 2 2 0 Smg-4/UPF3 family DUF77 PF01910.12 CCD24560.1 - 6.5e-16 57.7 0.1 7.5e-16 57.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 WD40 PF00400.27 CCD24561.1 - 2.4e-05 24.0 0.0 0.0071 16.1 0.0 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat PBP1_TM PF14812.1 CCD24561.1 - 2.6 8.4 6.8 1.4 9.2 2.6 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GSHPx PF00255.14 CCD24562.1 - 7.7e-48 160.3 0.6 9.8e-48 160.0 0.4 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CCD24562.1 - 1.1e-05 25.0 0.1 7e-05 22.5 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCD24562.1 - 0.00071 19.1 0.1 0.0041 16.6 0.1 2.0 1 1 0 1 1 1 1 Redoxin PA PF02225.17 CCD24562.1 - 0.15 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 PA domain WD40 PF00400.27 CCD24563.1 - 8.3e-05 22.3 22.5 0.025 14.4 0.1 6.6 8 0 0 8 8 8 3 WD domain, G-beta repeat Lgl_C PF08596.5 CCD24563.1 - 0.0048 15.4 1.0 0.05 12.0 0.1 2.5 2 1 1 3 3 3 1 Lethal giant larvae(Lgl) like, C-terminal DIE2_ALG10 PF04922.7 CCD24564.1 - 2.5e-119 398.7 41.8 4.4e-119 397.8 29.0 1.4 1 0 0 1 1 1 1 DIE2/ALG10 family SMI1_KNR4 PF09346.5 CCD24565.1 - 2.9e-32 111.4 0.0 2.9e-32 111.4 0.0 3.3 3 1 1 4 4 4 1 SMI1 / KNR4 family (SUKH-1) SPX PF03105.14 CCD24565.1 - 4.5 6.9 31.4 4.4 6.9 0.2 2.5 2 0 0 2 2 2 0 SPX domain Spo12 PF05032.7 CCD24566.1 - 3.1e-18 65.0 5.3 3.1e-18 65.0 3.7 2.3 2 0 0 2 2 2 1 Spo12 family Band_7 PF01145.20 CCD24567.1 - 1.1e-21 77.5 1.1 1.6e-21 77.0 0.8 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ank_2 PF12796.2 CCD24568.1 - 3.3e-53 177.9 3.4 5.6e-19 68.2 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CCD24568.1 - 9.7e-39 129.2 0.3 4.5e-09 35.6 0.0 6.1 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 CCD24568.1 - 2e-37 126.3 0.2 1.4e-10 41.0 0.0 5.8 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCD24568.1 - 3.9e-37 125.9 1.4 1.9e-10 40.9 0.0 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD24568.1 - 2.9e-32 107.4 0.3 3.3e-06 26.8 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Shigella_OspC PF06128.6 CCD24568.1 - 1.2e-05 25.0 0.3 0.00041 19.9 0.1 2.1 2 0 0 2 2 2 1 Shigella flexneri OspC protein DUF2019 PF09450.5 CCD24568.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2019) SPX PF03105.14 CCD24569.1 - 6.6e-30 104.8 16.8 6.6e-30 104.8 11.6 3.9 3 1 0 3 3 3 1 SPX domain Ank_2 PF12796.2 CCD24569.1 - 6.9e-30 103.2 4.3 2.4e-13 50.2 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CCD24569.1 - 2.2e-26 90.2 8.2 0.00015 21.3 0.0 6.6 6 0 0 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 CCD24569.1 - 4e-25 87.6 7.6 2e-08 34.5 0.0 5.3 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD24569.1 - 1.4e-21 74.3 8.7 0.0071 16.4 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 CCD24569.1 - 4.2e-17 61.7 9.9 0.0085 16.3 0.1 5.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) BRCT PF00533.21 CCD24570.1 - 1.1e-13 51.0 10.4 2.8e-05 24.1 0.1 4.7 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCD24570.1 - 8.8e-08 31.9 0.0 2.6e-05 23.9 0.0 3.1 3 0 0 3 3 3 2 twin BRCT domain FAD_binding_6 PF00970.19 CCD24571.1 - 1.1e-10 41.5 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 CCD24571.1 - 1.9e-09 37.8 0.0 7.5e-09 35.9 0.0 2.0 2 0 0 2 2 2 1 Globin NAD_binding_1 PF00175.16 CCD24571.1 - 1.3e-06 28.9 0.0 4.7e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Glyco_hydro_3_C PF01915.17 CCD24571.1 - 0.004 16.7 0.0 0.0088 15.5 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain NAD_binding_6 PF08030.7 CCD24571.1 - 0.056 13.3 0.1 0.22 11.4 0.0 1.9 1 1 1 2 2 2 0 Ferric reductase NAD binding domain Protoglobin PF11563.3 CCD24571.1 - 0.063 12.9 0.1 0.22 11.1 0.0 1.8 1 1 0 1 1 1 0 Protoglobin ApoO PF09769.4 CCD24572.1 - 4.6e-38 130.4 0.0 6e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Apolipoprotein O SSPI PF14098.1 CCD24572.1 - 0.13 12.2 0.0 0.43 10.5 0.0 1.8 2 0 0 2 2 2 0 Small, acid-soluble spore protein I Taeniidae_ag PF05596.6 CCD24573.1 - 0.02 14.7 0.6 0.051 13.3 0.4 1.7 1 0 0 1 1 1 0 Taeniidae antigen Kelch_5 PF13854.1 CCD24574.1 - 1.9e-36 123.4 9.1 3.1e-06 27.0 0.6 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 CCD24574.1 - 5.7e-36 121.8 4.9 6.6e-07 29.3 0.0 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CCD24574.1 - 1.2e-30 105.0 13.3 3.3e-05 23.5 0.2 7.1 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.1 CCD24574.1 - 2.6e-27 93.8 10.7 1.9e-05 24.5 0.1 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 CCD24574.1 - 6.2e-26 89.6 6.5 1.6e-09 37.1 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CCD24574.1 - 1.6e-15 56.1 7.8 0.012 15.3 0.0 6.8 6 0 0 6 6 6 5 Kelch motif PFK PF00365.15 CCD24576.1 - 2.2e-166 551.8 4.5 2.1e-124 414.0 1.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 CCD24576.1 - 0.48 10.0 1.8 1.2 8.7 0.3 2.2 2 0 0 2 2 2 0 UvrB/uvrC motif TT_ORF1 PF02956.9 CCD24577.1 - 0.054 11.9 26.1 0.048 12.1 18.1 1.2 1 0 0 1 1 1 0 TT viral orf 1 DUF1509 PF07420.6 CCD24577.1 - 0.18 11.0 12.1 0.15 11.2 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) BLVR PF06375.6 CCD24577.1 - 2.1 8.1 15.2 2.9 7.6 10.5 1.3 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DUF1708 PF08101.6 CCD24578.1 - 5.2e-157 522.9 10.7 1.1e-156 521.8 7.4 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) GTP_EFTU PF00009.22 CCD24579.1 - 2.8e-62 209.4 0.3 3.9e-62 209.0 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCD24579.1 - 3.7e-27 94.3 0.1 9e-27 93.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCD24579.1 - 5.8e-21 74.3 2.1 1.5e-20 73.0 1.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCD24579.1 - 1.6e-05 24.4 0.2 4e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCD24579.1 - 8e-05 22.5 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCD24579.1 - 0.0017 18.8 0.1 0.003 18.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CCD24579.1 - 0.024 14.1 0.3 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DisA_N PF02457.11 CCD24579.1 - 0.036 13.2 0.2 0.15 11.2 0.0 2.0 2 0 0 2 2 2 0 DisA bacterial checkpoint controller nucleotide-binding ATP_sub_h PF10775.4 CCD24580.1 - 4.5e-12 45.5 0.1 9.5e-12 44.4 0.0 1.5 1 0 0 1 1 1 1 ATP synthase complex subunit h DUF2407 PF10302.4 CCD24580.1 - 0.01 16.0 0.2 0.014 15.5 0.2 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ras PF00071.17 CCD24581.1 - 3.7e-50 169.4 0.0 4.5e-50 169.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD24581.1 - 8.2e-17 61.7 0.0 1.8e-16 60.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCD24581.1 - 2.7e-11 43.0 0.0 3.7e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 CCD24581.1 - 0.0006 19.9 0.2 0.0067 16.5 0.1 2.2 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 CCD24581.1 - 0.0037 16.4 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CCD24581.1 - 0.013 14.1 1.6 0.55 8.8 0.1 2.8 2 1 1 3 3 3 0 G-protein alpha subunit Pox_A32 PF04665.7 CCD24581.1 - 0.024 13.9 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein SRPRB PF09439.5 CCD24581.1 - 0.029 13.6 0.0 0.049 12.8 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CCD24581.1 - 0.039 14.1 0.2 0.16 12.1 0.1 2.0 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.1 CCD24581.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CCD24581.1 - 0.07 12.2 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 CCD24581.1 - 0.15 11.6 0.2 0.29 10.7 0.0 1.5 2 0 0 2 2 2 0 NACHT domain IF-2B PF01008.12 CCD24582.1 - 5.7e-89 297.8 1.2 4.4e-88 294.9 0.8 1.9 1 1 0 1 1 1 1 Initiation factor 2 subunit family DUF1804 PF08822.6 CCD24582.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1804) DUF2621 PF11084.3 CCD24582.1 - 0.12 11.9 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2621) Aminotran_5 PF00266.14 CCD24583.1 - 1.5e-36 125.9 0.0 2.6e-36 125.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V Ribosomal_S30 PF04758.9 CCD24584.1 - 1.3e-29 101.7 4.5 1.5e-29 101.5 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 WH1 PF00568.18 CCD24585.1 - 1.3e-35 121.4 0.0 1.9e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 CCD24585.1 - 1.2e-05 24.7 0.8 2.6e-05 23.6 0.5 1.6 1 0 0 1 1 1 1 WH2 motif ECH PF00378.15 CCD24586.1 - 2.9e-16 59.3 0.0 1.6e-15 56.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Fungal_trans PF04082.13 CCD24587.1 - 2.6e-18 65.8 2.4 4.9e-18 64.9 1.6 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD24587.1 - 7.2e-06 25.8 10.8 1.8e-05 24.5 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CBM_21 PF03370.8 CCD24588.1 - 2.8e-27 94.9 8.7 2.8e-27 94.9 6.0 3.0 3 0 0 3 3 3 1 Putative phosphatase regulatory subunit Pkinase PF00069.20 CCD24589.1 - 1.9e-71 240.2 0.5 5.7e-65 219.0 0.0 2.8 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24589.1 - 1.2e-34 119.5 0.0 1.3e-32 112.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CCD24589.1 - 0.011 14.7 0.0 0.028 13.4 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD24589.1 - 0.02 14.6 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Utp11 PF03998.8 CCD24590.1 - 6.4e-71 239.0 29.4 7.3e-71 238.8 20.4 1.0 1 0 0 1 1 1 1 Utp11 protein Phospholip_B PF04916.8 CCD24590.1 - 0.013 13.5 0.4 0.019 13.1 0.3 1.2 1 0 0 1 1 1 0 Phospholipase B DUF2529 PF10740.4 CCD24590.1 - 0.014 14.8 0.0 0.025 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) DUF1481 PF07356.7 CCD24590.1 - 2.2 7.6 10.9 0.1 12.0 3.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1481) BRO1 PF03097.13 CCD24591.1 - 0.074 11.7 0.7 0.16 10.7 0.3 1.6 2 0 0 2 2 2 0 BRO1-like domain Ribosomal_L29 PF00831.18 CCD24592.1 - 0.028 14.1 0.6 0.08 12.6 0.4 1.7 1 0 0 1 1 1 0 Ribosomal L29 protein UPF0147 PF03685.8 CCD24592.1 - 0.17 11.7 2.4 0.46 10.3 0.5 2.2 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0147) Mod_r PF07200.8 CCD24592.1 - 0.21 11.5 3.8 0.8 9.6 2.6 1.8 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein TFIIS_M PF07500.9 CCD24593.1 - 1e-29 102.9 1.3 1e-29 102.9 0.9 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CCD24593.1 - 1.7e-17 62.7 6.3 3.1e-17 61.8 4.4 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CCD24593.1 - 1e-13 50.5 2.3 1e-13 50.5 1.6 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Phyto_Pns9_10 PF05878.6 CCD24593.1 - 0.037 13.0 4.9 0.062 12.2 3.4 1.3 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 Ribosomal_S27 PF01599.14 CCD24593.1 - 0.25 11.2 2.5 2 8.2 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S27a Gly_radical PF01228.16 CCD24593.1 - 1.5 9.2 5.5 0.43 10.9 0.4 2.4 2 1 0 2 2 2 0 Glycine radical Zn_Tnp_IS1595 PF12760.2 CCD24593.1 - 1.6 8.5 5.5 6 6.7 3.9 1.9 1 1 0 1 1 1 0 Transposase zinc-ribbon domain RRM_1 PF00076.17 CCD24594.1 - 2e-20 72.2 0.0 4.7e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD24594.1 - 1.5e-14 53.7 0.0 2.9e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD24594.1 - 4.3e-10 39.2 0.0 7.2e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 CCD24594.1 - 5.4e-05 23.1 0.3 5.4e-05 23.1 0.2 2.0 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 CCD24594.1 - 0.00013 21.1 0.2 0.00029 20.0 0.2 1.5 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal ASF1_hist_chap PF04729.8 CCD24594.1 - 0.0064 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 ASF1 like histone chaperone zf-RING_2 PF13639.1 CCD24595.1 - 3.7e-09 36.2 1.8 3.7e-09 36.2 1.3 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CCD24595.1 - 1.2e-05 25.2 7.1 1.2e-05 25.2 4.9 2.1 1 1 1 2 2 2 1 RING-H2 zinc finger FANCL_C PF11793.3 CCD24595.1 - 0.0042 17.0 7.1 0.0073 16.2 4.5 1.9 1 1 0 1 1 1 1 FANCL C-terminal domain zf-C3HC4_2 PF13923.1 CCD24595.1 - 0.0077 16.2 4.8 0.0077 16.2 3.3 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCD24595.1 - 0.017 14.7 8.2 0.13 11.9 5.7 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCD24595.1 - 0.025 14.3 2.0 0.035 13.8 0.4 2.1 1 1 0 1 1 1 0 RING-type zinc-finger DUF2157 PF09925.4 CCD24595.1 - 0.13 11.8 0.8 0.19 11.3 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) zf-RING_5 PF14634.1 CCD24595.1 - 1.1 9.0 8.8 4.6 7.0 6.1 2.1 1 1 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 CCD24595.1 - 3.1 7.7 9.9 7 6.5 5.1 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger RNase_PH PF01138.16 CCD24596.1 - 4.5e-16 59.3 0.2 6.5e-16 58.8 0.1 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 Arrestin_N PF00339.24 CCD24597.1 - 6.3e-19 68.2 2.0 1.2e-18 67.3 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CCD24597.1 - 1.1e-05 25.6 0.3 1.1e-05 25.6 0.2 4.1 3 2 1 4 4 4 2 Arrestin (or S-antigen), C-terminal domain RRM_1 PF00076.17 CCD24598.1 - 2.7e-45 151.8 0.0 1.9e-21 75.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD24598.1 - 4.2e-29 100.3 0.0 2.2e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD24598.1 - 9.6e-22 76.5 0.0 3.2e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCD24598.1 - 0.0015 18.2 0.1 0.29 10.9 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif AAA PF00004.24 CCD24599.1 - 5.5e-43 146.3 0.0 1e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCD24599.1 - 8.3e-07 28.8 0.0 5.5e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCD24599.1 - 1e-06 28.7 0.0 2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCD24599.1 - 5e-06 26.6 0.1 0.00031 20.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCD24599.1 - 1.8e-05 24.7 0.0 0.00011 22.2 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CCD24599.1 - 4.2e-05 24.3 0.3 0.00015 22.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCD24599.1 - 0.00013 21.6 0.1 0.00031 20.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CCD24599.1 - 0.00013 21.0 0.0 0.00024 20.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CCD24599.1 - 0.00025 20.5 0.0 0.00044 19.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCD24599.1 - 0.0012 18.7 0.0 0.0023 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCD24599.1 - 0.0018 18.1 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCD24599.1 - 0.0018 18.2 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCD24599.1 - 0.003 16.6 0.0 0.0068 15.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 CCD24599.1 - 0.0055 16.3 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2072 PF09845.4 CCD24599.1 - 0.0079 16.1 0.3 0.017 15.0 0.2 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) AAA_18 PF13238.1 CCD24599.1 - 0.0083 16.4 1.0 0.035 14.4 0.0 2.5 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 CCD24599.1 - 0.0096 14.6 0.0 0.023 13.4 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 CCD24599.1 - 0.0097 15.0 0.2 0.025 13.7 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CCD24599.1 - 0.015 14.5 0.0 0.046 12.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 CCD24599.1 - 0.024 14.1 0.0 0.14 11.6 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 CCD24599.1 - 0.025 13.9 0.1 0.097 12.0 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 CCD24599.1 - 0.032 13.8 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCD24599.1 - 0.034 14.3 0.0 0.079 13.1 0.0 1.7 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.7 CCD24599.1 - 0.049 13.2 0.0 0.36 10.4 0.0 2.1 1 1 1 2 2 2 0 NACHT domain DUF815 PF05673.8 CCD24599.1 - 0.057 12.3 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 CCD24599.1 - 0.062 12.1 0.0 0.13 11.0 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 CCD24599.1 - 0.09 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MIF4G PF02854.14 CCD24600.1 - 1.1e-48 165.4 1.0 1.8e-48 164.7 0.7 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 CCD24600.1 - 3.7e-22 77.9 1.9 3.7e-22 77.9 1.3 3.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 TYW3 PF02676.9 CCD24601.1 - 4.6e-66 221.8 0.3 1.1e-65 220.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase TYW3 DUF2347 PF09804.4 CCD24601.1 - 0.045 13.0 0.5 0.061 12.5 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Cys_Met_Meta_PP PF01053.15 CCD24602.1 - 3.1e-145 483.3 0.0 3.6e-145 483.0 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCD24602.1 - 2.9e-11 43.0 0.0 4.7e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CCD24602.1 - 1.5e-10 40.6 0.0 2.2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCD24602.1 - 4.1e-09 35.6 0.1 5.9e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCD24602.1 - 2.3e-07 30.2 0.0 3.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 CCD24602.1 - 0.00035 19.0 0.1 0.00071 17.9 0.1 1.5 1 1 0 1 1 1 1 Methionine gamma-lyase GDC-P PF02347.11 CCD24602.1 - 0.0043 15.8 0.0 0.0059 15.3 0.0 1.1 1 0 0 1 1 1 1 Glycine cleavage system P-protein Phg_2220_C PF09524.5 CCD24602.1 - 0.0099 15.8 0.0 0.16 11.9 0.0 2.5 2 0 0 2 2 2 1 Conserved phage C-terminus (Phg_2220_C) CPSase_L_D2 PF02786.12 CCD24602.1 - 0.16 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain Aconitase PF00330.15 CCD24603.1 - 1.4e-181 604.0 0.0 3.7e-181 602.6 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCD24603.1 - 1.7e-47 160.8 0.0 3.4e-47 159.8 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain PI3_PI4_kinase PF00454.22 CCD24604.1 - 9.5e-43 146.3 0.0 4.6e-42 144.1 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CCD24604.1 - 6.4e-27 93.9 0.1 1.9e-26 92.3 0.1 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) UQ_con PF00179.21 CCD24605.1 - 2.8e-34 117.5 0.0 3.7e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme U3_snoRNA_assoc PF08297.6 CCD24605.1 - 0.046 13.9 0.3 0.077 13.2 0.2 1.2 1 0 0 1 1 1 0 U3 snoRNA associated Prok-E2_B PF14461.1 CCD24605.1 - 0.1 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B Polysacc_deac_1 PF01522.16 CCD24606.1 - 1.9e-25 88.8 0.0 3e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase GRIP PF01465.15 CCD24607.1 - 5.9e-15 54.4 0.5 1.6e-14 53.1 0.4 1.8 1 0 0 1 1 1 1 GRIP domain IncA PF04156.9 CCD24607.1 - 0.00071 19.2 143.3 0.21 11.1 13.1 7.8 2 2 5 8 8 8 7 IncA protein GAS PF13851.1 CCD24607.1 - 0.0039 16.3 12.6 0.0039 16.3 8.7 8.4 1 1 7 8 8 8 4 Growth-arrest specific micro-tubule binding Spc7 PF08317.6 CCD24607.1 - 5.6 5.5 147.8 0.41 9.2 12.2 6.5 1 1 5 6 6 6 0 Spc7 kinetochore protein RasGEF PF00617.14 CCD24608.1 - 1.6e-61 207.2 1.0 5.9e-61 205.4 0.1 2.5 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CCD24608.1 - 1.3e-16 60.5 0.0 2e-15 56.7 0.0 3.2 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 CCD24608.1 - 9.9e-09 34.6 0.1 2.2e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCD24608.1 - 7.9e-07 28.3 0.1 2.7e-06 26.6 0.1 2.0 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCD24608.1 - 0.00042 19.7 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain tRNA-synt_2 PF00152.15 CCD24609.1 - 1e-80 271.0 0.3 1e-80 271.0 0.2 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCD24609.1 - 3.9e-07 29.8 0.3 9.1e-07 28.6 0.2 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCD24609.1 - 0.0065 15.6 0.7 1.4 8.0 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Cytadhesin_P30 PF07271.6 CCD24609.1 - 0.24 10.6 1.8 0.44 9.7 1.2 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 SR-25 PF10500.4 CCD24609.1 - 0.31 10.4 7.4 0.44 9.9 5.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein COX6B PF02297.12 CCD24610.1 - 0.041 13.8 0.3 0.064 13.2 0.2 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Arteri_env PF01606.11 CCD24610.1 - 0.041 13.5 0.0 0.05 13.2 0.0 1.0 1 0 0 1 1 1 0 Arterivirus envelope protein CHCH PF06747.8 CCD24610.1 - 0.093 12.6 3.0 0.62 10.0 2.0 2.1 1 1 1 2 2 2 0 CHCH domain Pet191_N PF10203.4 CCD24610.1 - 0.26 11.3 2.5 1.2 9.1 1.8 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Pkinase PF00069.20 CCD24611.1 - 3.6e-41 141.0 6.8 5.1e-41 140.5 0.2 3.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24611.1 - 1.7e-11 43.6 0.8 7.5e-11 41.5 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase CDK2AP PF09806.4 CCD24611.1 - 3.3e-05 24.1 7.7 3.3e-05 24.1 5.3 2.6 2 0 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein DUF106 PF01956.11 CCD24611.1 - 0.031 13.8 2.7 39 3.7 6.0 2.8 2 1 0 2 2 2 0 Integral membrane protein DUF106 Rpp20 PF12328.3 CCD24611.1 - 0.11 12.1 8.5 0.47 10.0 5.9 2.1 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Auxin_canalis PF05703.6 CCD24611.1 - 0.96 9.2 6.0 2.4 7.8 4.2 1.6 1 0 0 1 1 1 0 Auxin canalisation Mem_trans PF03547.13 CCD24611.1 - 3 6.0 6.8 0.097 10.9 0.1 1.9 2 0 0 2 2 2 0 Membrane transport protein GIT_SHD PF08518.6 CCD24612.1 - 4e-26 90.0 4.5 4.2e-14 51.5 0.1 2.6 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT TPR_11 PF13414.1 CCD24613.1 - 0.00083 18.9 0.3 1.1 8.9 0.0 2.7 2 0 0 2 2 2 2 TPR repeat SHNi-TPR PF10516.4 CCD24613.1 - 0.0027 16.9 0.0 0.045 12.9 0.0 2.7 3 0 0 3 3 3 1 SHNi-TPR TPR_12 PF13424.1 CCD24613.1 - 0.0066 16.3 0.3 2.8 7.9 0.0 2.8 2 2 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCD24613.1 - 0.062 12.9 4.1 1.2 8.8 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCD24613.1 - 0.12 12.1 3.5 19 5.3 0.0 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat SDA1 PF05285.7 CCD24613.1 - 5 6.3 29.2 0.22 10.7 16.1 1.7 2 0 0 2 2 2 0 SDA1 UPF0121 PF03661.8 CCD24614.1 - 1.8e-09 37.1 10.5 2.4e-09 36.7 7.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) rve PF00665.21 CCD24615.1 - 1.8e-06 28.0 0.0 4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Ribosomal_S3Ae PF01015.13 CCD24617.1 - 3.4e-81 271.2 7.3 4e-81 271.0 5.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 CCD24617.1 - 0.043 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region SpoVIF PF14069.1 CCD24617.1 - 0.33 10.7 2.8 4.7 7.0 0.6 2.5 1 1 1 2 2 2 0 Stage VI sporulation protein F Ras PF00071.17 CCD24618.1 - 3.7e-28 97.9 0.0 4.4e-28 97.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD24618.1 - 8.5e-18 64.9 0.0 1.3e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CCD24618.1 - 0.0014 17.8 0.1 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CCD24618.1 - 0.0018 17.5 0.1 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCD24618.1 - 0.0065 16.4 0.0 0.0088 15.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Folliculin PF11704.3 CCD24618.1 - 0.054 13.0 0.0 0.095 12.2 0.0 1.3 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Arch_ATPase PF01637.13 CCD24618.1 - 0.06 13.0 0.1 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 CCD24619.1 - 3e-18 66.2 0.0 6.8e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 CCD24619.1 - 7.4e-11 41.8 0.1 1.7e-10 40.6 0.1 1.7 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 CCD24619.1 - 1e-05 25.6 0.1 4.9e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCD24619.1 - 0.00013 21.7 0.2 0.00013 21.7 0.1 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 CCD24619.1 - 0.0011 19.0 0.0 0.0042 17.1 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.7 CCD24619.1 - 0.015 14.9 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 CCD24619.1 - 0.027 14.6 0.0 0.39 10.9 0.0 3.0 2 0 0 2 2 2 0 RNA helicase AAA_19 PF13245.1 CCD24619.1 - 0.04 13.6 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 CCD24619.1 - 0.069 13.4 0.0 0.069 13.4 0.0 3.9 4 1 0 4 4 4 0 AAA domain AAA_17 PF13207.1 CCD24619.1 - 0.29 11.9 2.8 1.2 10.0 0.0 3.4 4 1 0 4 4 4 0 AAA domain RVT_2 PF07727.9 CCD24620.1 - 7.4e-41 139.7 0.6 1.3e-40 138.8 0.4 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCD24620.1 - 1.1e-16 61.0 0.0 2.7e-16 59.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCD24620.1 - 2.8e-05 23.6 0.1 8.8e-05 22.0 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain Dioxygenase_N PF04444.9 CCD24620.1 - 0.19 11.7 0.4 3 7.8 0.0 2.8 2 0 0 2 2 2 0 Catechol dioxygenase N terminus Methyltransf_FA PF12248.3 CCD24621.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Farnesoic acid 0-methyl transferase COPIIcoated_ERV PF07970.7 CCD24622.1 - 1.4e-29 103.3 0.2 2e-29 102.8 0.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCD24622.1 - 1.8e-19 69.5 0.0 4.2e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) IBR PF01485.16 CCD24623.1 - 1.4e-14 53.7 25.3 9e-09 35.0 9.4 4.0 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 CCD24623.1 - 0.00072 19.3 8.5 0.00072 19.3 5.9 3.9 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 CCD24623.1 - 0.016 15.2 10.6 0.016 15.2 7.4 4.4 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) RWD PF05773.17 CCD24623.1 - 0.024 14.5 0.4 0.27 11.1 0.1 2.4 2 0 0 2 2 2 0 RWD domain SSrecog PF03531.9 CCD24624.1 - 1.8e-68 230.2 3.0 3.5e-67 225.9 1.3 2.7 2 1 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CCD24624.1 - 2.7e-30 104.2 0.2 8.1e-28 96.2 0.0 3.1 3 0 0 3 3 3 2 Histone chaperone Rttp106-like Dak1 PF02733.12 CCD24625.1 - 7.4e-137 455.2 3.0 9.7e-137 454.8 2.1 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 CCD24625.1 - 1.1e-43 148.9 1.9 2e-43 148.0 1.3 1.5 1 0 0 1 1 1 1 DAK2 domain Dor1 PF04124.7 CCD24626.1 - 1.1e-46 158.9 8.1 1.8e-46 158.1 5.6 1.3 1 0 0 1 1 1 1 Dor1-like family Sec5 PF15469.1 CCD24626.1 - 6.5e-05 22.7 2.2 6.5e-05 22.7 1.5 2.7 1 1 1 2 2 2 1 Exocyst complex component Sec5 Clathrin PF00637.15 CCD24626.1 - 0.017 14.6 1.6 0.19 11.3 0.1 3.1 2 1 0 2 2 2 0 Region in Clathrin and VPS Lipoxygenase PF00305.14 CCD24626.1 - 0.025 12.5 0.5 0.045 11.7 0.3 1.3 1 0 0 1 1 1 0 Lipoxygenase RP-C_C PF11800.3 CCD24626.1 - 0.22 11.1 2.3 0.39 10.3 1.6 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF1843 PF08898.5 CCD24626.1 - 0.65 10.0 3.2 7.9 6.6 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Vps51 PF08700.6 CCD24626.1 - 0.94 9.3 7.3 5.3 6.9 0.1 3.9 3 1 1 4 4 4 0 Vps51/Vps67 CENP-H PF05837.7 CCD24626.1 - 2.3 8.4 10.1 1.9 8.6 2.3 2.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) C2 PF00168.25 CCD24627.1 - 1.8e-52 175.0 4.0 2.7e-20 71.9 0.0 6.3 6 0 0 6 6 6 5 C2 domain DOCK-C2 PF14429.1 CCD24627.1 - 0.004 16.8 2.6 0.046 13.3 0.0 3.5 3 1 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins Ribosomal_L6e PF01159.14 CCD24628.1 - 1.9e-39 134.2 1.2 2.7e-39 133.7 0.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Piwi PF02171.12 CCD24629.1 - 2.1e-62 210.8 0.0 3.1e-62 210.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CCD24629.1 - 1.1e-05 24.7 2.4 3.5e-05 23.1 1.6 1.8 1 1 0 1 1 1 1 PAZ domain FKBP_C PF00254.23 CCD24630.1 - 6.5e-28 96.5 0.0 6.5e-28 96.5 0.0 2.5 3 1 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase Paf1 PF03985.8 CCD24630.1 - 0.0042 15.8 10.2 0.0042 15.8 7.1 2.9 2 1 1 3 3 3 1 Paf1 Peptidase_S49_N PF08496.5 CCD24630.1 - 0.19 11.5 21.0 0.49 10.1 0.9 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DcuC PF03606.10 CCD24630.1 - 0.95 7.6 0.0 0.95 7.6 0.0 2.0 3 0 0 3 3 3 0 C4-dicarboxylate anaerobic carrier RNase_H2-Ydr279 PF09468.5 CCD24630.1 - 1.1 8.3 24.9 0.68 9.0 8.0 2.3 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) SDA1 PF05285.7 CCD24630.1 - 1.6 7.9 56.0 2.4 7.3 11.8 2.1 2 0 0 2 2 2 0 SDA1 RR_TM4-6 PF06459.7 CCD24630.1 - 2.8 7.7 36.8 1.5 8.6 4.8 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CCD24630.1 - 4 7.1 22.2 5.6 6.6 2.9 2.2 2 0 0 2 2 2 0 DDHD domain TFIIF_alpha PF05793.7 CCD24630.1 - 9.5 4.4 66.6 0.013 13.8 12.9 2.1 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HMG-CoA_red PF00368.13 CCD24631.1 - 2e-158 526.9 0.1 2.6e-158 526.5 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 CCD24631.1 - 8.7e-42 142.4 0.6 2.1e-41 141.1 0.4 1.7 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 CCD24631.1 - 0.002 17.6 9.1 0.002 17.6 6.3 2.3 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Zn_clus PF00172.13 CCD24632.1 - 0.00073 19.3 8.9 0.0014 18.4 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sybindin PF04099.7 CCD24633.1 - 5.7e-19 68.2 0.4 6.7e-19 68.0 0.2 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CCD24633.1 - 0.00061 19.6 0.2 0.00072 19.4 0.1 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region OstA_C PF04453.9 CCD24633.1 - 0.0025 16.9 1.2 0.0031 16.6 0.8 1.1 1 0 0 1 1 1 1 Organic solvent tolerance protein ENTH PF01417.15 CCD24634.1 - 1.7e-45 153.9 0.1 1.7e-45 153.9 0.0 1.9 2 0 0 2 2 2 1 ENTH domain ANTH PF07651.11 CCD24634.1 - 3.1e-05 22.8 0.0 4.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 ANTH domain VHS PF00790.14 CCD24634.1 - 0.0042 16.7 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 VHS domain Pro_isomerase PF00160.16 CCD24635.1 - 2.7e-50 170.5 0.5 3.1e-50 170.4 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cupin_5 PF06172.6 CCD24636.1 - 6.2e-35 120.1 0.0 8e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Dus PF01207.12 CCD24637.1 - 2.4e-78 263.1 0.0 3.1e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-C2H2 PF00096.21 CCD24638.1 - 1.1e-06 28.6 15.2 0.00012 22.1 2.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCD24638.1 - 1.5e-06 28.1 11.3 2.4e-05 24.4 3.5 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCD24638.1 - 0.085 13.2 16.9 0.15 12.4 2.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger ATP-synt_J PF04911.7 CCD24639.1 - 8.5e-26 89.1 0.1 9.6e-26 89.0 0.1 1.1 1 0 0 1 1 1 1 ATP synthase j chain Cys_Met_Meta_PP PF01053.15 CCD24640.1 - 1.5e-22 79.4 0.0 2.1e-11 42.7 0.0 2.9 3 0 0 3 3 3 2 Cys/Met metabolism PLP-dependent enzyme TetR_C_8 PF14278.1 CCD24640.1 - 0.49 10.8 2.9 1.3 9.4 1.1 2.5 1 1 0 1 1 1 0 Transcriptional regulator C-terminal region TPP_enzyme_M PF00205.17 CCD24641.1 - 5.4e-35 120.1 0.0 3.1e-34 117.6 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 CCD24641.1 - 4e-21 75.2 0.2 6.3e-21 74.6 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCD24641.1 - 1.2e-14 54.1 0.0 2.5e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Ctf8 PF09696.5 CCD24642.1 - 4.1e-28 97.6 0.1 5.4e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Ctf8 DUF2296 PF10058.4 CCD24643.1 - 2.6e-14 52.7 1.1 6.1e-14 51.5 0.8 1.7 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) UPF0104 PF03706.8 CCD24643.1 - 0.0093 15.2 0.0 0.012 14.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF4271 PF14093.1 CCD24643.1 - 0.01 15.5 0.2 0.01 15.5 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF1191 PF06697.7 CCD24643.1 - 0.022 13.6 0.0 0.059 12.1 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) 2TM PF13239.1 CCD24643.1 - 0.042 13.8 0.3 0.078 13.0 0.2 1.4 1 0 0 1 1 1 0 2TM domain End3 PF12761.2 CCD24643.1 - 0.048 13.3 0.4 0.048 13.3 0.2 2.7 3 1 0 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 TF_Zn_Ribbon PF08271.7 CCD24643.1 - 0.076 12.3 4.8 0.26 10.6 3.3 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding Allexi_40kDa PF05549.6 CCD24643.1 - 0.21 10.8 5.3 3.3 6.9 0.3 2.3 2 0 0 2 2 2 0 Allexivirus 40kDa protein zf-ISL3 PF14690.1 CCD24643.1 - 0.28 11.2 3.4 0.82 9.7 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 USP8_interact PF08941.5 CCD24643.1 - 0.42 9.9 0.0 0.42 9.9 0.0 2.7 3 1 1 4 4 4 0 USP8 interacting Cep57_CLD_2 PF14197.1 CCD24643.1 - 1.7 8.6 11.1 0.75 9.7 4.9 2.5 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF489 PF04356.7 CCD24643.1 - 2.4 7.7 6.1 5.8 6.4 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF489) NAC PF01849.13 CCD24644.1 - 4e-16 58.2 1.0 1.9e-15 56.1 0.1 2.1 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 CCD24644.1 - 0.00019 21.1 0.2 0.00061 19.5 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 CCD24644.1 - 0.01 15.3 0.4 0.027 13.9 0.0 1.9 2 0 0 2 2 2 0 UBA-like domain MDM31_MDM32 PF08118.6 CCD24645.1 - 1.9e-238 791.9 9.1 2.3e-238 791.6 6.3 1.1 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins TraC PF07820.7 CCD24645.1 - 0.14 12.3 0.1 0.28 11.3 0.1 1.4 1 0 0 1 1 1 0 TraC-like protein DUF3879 PF12995.2 CCD24646.1 - 0.014 15.0 2.1 0.015 14.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3879) RIX1 PF08167.7 CCD24647.1 - 3.3e-43 147.2 7.3 5.1e-43 146.6 4.1 2.1 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis DUF281 PF03436.8 CCD24647.1 - 0.0071 16.3 0.3 0.087 12.8 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF281) Chalcone PF02431.10 CCD24648.1 - 6.7e-46 156.1 0.0 1.1e-45 155.5 0.0 1.3 1 0 0 1 1 1 1 Chalcone-flavanone isomerase VWA_2 PF13519.1 CCD24649.1 - 2.3e-07 31.1 0.1 3.2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 CCD24649.1 - 0.00017 21.2 0.3 0.00027 20.5 0.2 1.3 1 0 0 1 1 1 1 Ssl1-like RAB3GAP2_N PF14655.1 CCD24649.1 - 0.32 9.9 6.1 5.9 5.7 3.0 2.1 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Homoserine_dh PF00742.14 CCD24650.1 - 7.8e-56 188.5 0.1 1.3e-55 187.8 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CCD24650.1 - 9e-21 74.4 0.0 1.7e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CCD24650.1 - 0.012 16.0 0.0 0.049 14.0 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DHC_N2 PF08393.8 CCD24650.1 - 0.16 10.4 0.1 0.27 9.6 0.1 1.3 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 2 DHHA2 PF02833.9 CCD24651.1 - 2.1e-23 82.8 0.8 3.8e-23 82.0 0.5 1.4 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 CCD24651.1 - 1.9e-09 37.3 0.3 8.8e-09 35.1 0.2 2.0 1 1 0 1 1 1 1 DHH family CWC25 PF12542.3 CCD24651.1 - 0.028 14.8 0.0 0.088 13.2 0.0 1.8 1 1 0 1 1 1 0 Pre-mRNA splicing factor Mgm101p PF06420.7 CCD24652.1 - 1.3e-88 294.8 0.3 2.6e-88 293.7 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial genome maintenance MGM101 Metallophos PF00149.23 CCD24653.1 - 5.3e-06 25.9 6.8 9.9e-06 25.0 4.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S4e PF00900.15 CCD24654.1 - 5.3e-33 112.5 1.5 3e-32 110.1 0.6 2.1 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CCD24654.1 - 6.9e-20 70.6 4.4 1.4e-19 69.6 3.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CCD24654.1 - 1.4e-07 30.8 0.5 2.6e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 CCD24654.1 - 1.1e-05 24.8 1.5 1.1e-05 24.8 1.0 3.3 4 0 0 4 4 4 1 KOW motif Glyco_hydro_47 PF01532.15 CCD24655.1 - 9.4e-119 397.0 0.0 1.2e-118 396.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.20 CCD24656.1 - 2.5e-69 233.3 0.0 2.6e-68 229.9 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24656.1 - 4.8e-31 107.7 0.0 1.8e-30 105.8 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCD24656.1 - 1.3e-11 44.8 1.1 1.3e-11 44.8 0.8 2.9 3 0 0 3 3 3 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCD24656.1 - 3.4e-09 36.0 0.0 7.8e-09 34.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 CCD24656.1 - 3.2e-07 30.1 1.7 0.00012 21.8 1.2 2.7 1 1 0 1 1 1 1 C2 domain YrbL-PhoP_reg PF10707.4 CCD24656.1 - 0.018 14.4 0.5 0.061 12.6 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL HSF_DNA-bind PF00447.12 CCD24657.1 - 5e-35 119.8 0.9 1.2e-34 118.5 0.6 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 CCD24657.1 - 1.2e-26 92.8 0.7 2.4e-26 91.9 0.5 1.5 1 0 0 1 1 1 1 Response regulator receiver domain SET PF00856.23 CCD24658.1 - 1.3e-13 51.5 0.0 7.5e-13 49.1 0.0 2.2 1 1 0 1 1 1 1 SET domain Myticin-prepro PF10690.4 CCD24658.1 - 0.0058 16.6 2.2 1.6 8.8 0.1 2.7 2 0 0 2 2 2 2 Myticin pre-proprotein from the mussel LepA_C PF06421.7 CCD24658.1 - 0.024 14.5 0.3 0.05 13.5 0.2 1.5 1 0 0 1 1 1 0 GTP-binding protein LepA C-terminus 4HBT PF03061.17 CCD24659.1 - 0.061 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily 5-FTHF_cyc-lig PF01812.15 CCD24660.1 - 4.1e-31 108.2 0.1 9.4e-31 107.0 0.1 1.6 1 1 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family Aminotran_4 PF01063.14 CCD24661.1 - 3.2e-30 105.3 0.0 4e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Fungal_trans PF04082.13 CCD24662.1 - 2.4e-09 36.4 4.5 2.4e-09 36.4 3.2 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD24662.1 - 2.4e-06 27.3 7.6 5.3e-06 26.2 5.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 CCD24663.1 - 2.3e-15 55.7 1.4 2.3e-05 24.1 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF2782 PF11191.3 CCD24663.1 - 0.0082 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2782) Nup160 PF11715.3 CCD24663.1 - 0.0088 14.2 0.2 1.2 7.1 0.0 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 F5_F8_type_C PF00754.20 CCD24663.1 - 0.04 13.7 0.9 0.1 12.4 0.4 2.0 1 1 0 1 1 1 0 F5/8 type C domain DUF1664 PF07889.7 CCD24664.1 - 0.00073 19.3 0.6 0.0037 17.0 0.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 CCD24664.1 - 0.0018 18.0 1.3 0.14 11.8 0.0 2.9 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding COG5 PF10392.4 CCD24664.1 - 0.002 18.1 5.5 0.082 12.8 0.2 3.1 2 1 1 3 3 3 2 Golgi transport complex subunit 5 UPF0158 PF03682.8 CCD24664.1 - 0.012 15.2 1.5 0.021 14.4 1.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) AATF-Che1 PF13339.1 CCD24664.1 - 0.035 14.2 4.0 0.11 12.5 1.5 2.5 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Syntaxin-6_N PF09177.6 CCD24664.1 - 0.035 14.4 6.6 2.8 8.4 0.1 3.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF4515 PF14988.1 CCD24664.1 - 0.049 13.3 0.2 0.049 13.3 0.1 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4515) DUF948 PF06103.6 CCD24664.1 - 0.099 12.5 3.3 0.66 9.8 0.1 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) ISG65-75 PF11727.3 CCD24664.1 - 0.1 11.6 0.3 0.23 10.5 0.1 1.6 1 1 0 1 1 1 0 Invariant surface glycoprotein Baculo_PEP_C PF04513.7 CCD24664.1 - 0.21 11.4 13.6 0.1 12.3 3.0 3.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBPIP PF07106.8 CCD24664.1 - 0.33 10.5 6.1 0.095 12.2 0.8 2.4 2 1 1 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fzo_mitofusin PF04799.8 CCD24664.1 - 0.56 9.5 4.8 8.2 5.7 0.7 3.3 2 1 0 3 3 3 0 fzo-like conserved region Reo_sigmaC PF04582.7 CCD24664.1 - 0.68 9.0 6.9 3.1 6.8 1.8 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein NPV_P10 PF05531.7 CCD24664.1 - 0.98 9.7 10.4 0.58 10.4 1.1 3.4 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein FliD_N PF02465.13 CCD24664.1 - 1 9.7 5.9 25 5.3 1.9 3.5 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Tropomyosin_1 PF12718.2 CCD24664.1 - 2.3 8.0 7.3 0.75 9.6 0.2 2.7 2 1 1 3 3 3 0 Tropomyosin like FliS PF02561.9 CCD24664.1 - 3.2 7.6 10.7 2.8 7.8 0.4 3.7 2 2 2 4 4 4 0 Flagellar protein FliS E1-E2_ATPase PF00122.15 CCD24665.1 - 1.4e-63 214.0 3.3 1.4e-63 214.0 2.3 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCD24665.1 - 4.4e-41 140.4 5.0 4.4e-41 140.4 3.5 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCD24665.1 - 1.1e-24 88.0 0.0 4.3e-24 86.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCD24665.1 - 6e-13 49.3 0.0 1.6e-12 48.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCD24665.1 - 4.1e-12 45.8 0.0 1.4e-11 44.1 0.0 2.0 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CCD24665.1 - 9.6e-08 31.3 0.0 3.9e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCD24665.1 - 0.00041 19.9 0.3 0.00041 19.9 0.2 3.2 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CCD24666.1 - 8.6e-63 211.4 5.7 8.6e-63 211.4 4.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCD24666.1 - 1.2e-24 87.9 0.0 2.2e-24 87.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCD24666.1 - 1.1e-15 58.3 0.0 2.9e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCD24666.1 - 6.5e-11 41.5 0.2 2.7e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCD24666.1 - 0.0014 18.2 0.1 0.0028 17.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCD24666.1 - 0.0072 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit PUF PF00806.14 CCD24667.1 - 3.3e-65 212.0 14.5 2.1e-09 36.3 0.2 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Fungal_trans PF04082.13 CCD24668.1 - 5.2e-30 104.1 1.6 5.2e-30 104.1 1.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD24668.1 - 3e-07 30.2 16.7 6e-07 29.2 11.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HypA PF01155.14 CCD24668.1 - 6.8 6.4 6.9 55 3.4 3.1 2.4 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Fungal_trans PF04082.13 CCD24669.1 - 3.8e-28 98.0 3.3 3.8e-28 98.0 2.3 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD24669.1 - 8.1e-08 32.0 15.4 1.8e-07 30.9 10.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.21 CCD24670.1 - 3.3e-33 114.5 0.1 3.8e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF962 PF06127.6 CCD24671.1 - 2.7e-26 91.2 0.6 5.5e-26 90.3 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF360 PF04020.8 CCD24671.1 - 0.11 12.8 4.5 0.17 12.2 3.1 1.4 1 1 0 1 1 1 0 Membrane protein of unknown function Aconitase PF00330.15 CCD24672.1 - 8.1e-192 637.8 0.0 9.9e-192 637.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCD24672.1 - 9.8e-46 155.1 0.0 2.1e-45 154.0 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain ATE_C PF04377.10 CCD24674.1 - 3.6e-39 133.7 0.8 6.1e-39 132.9 0.1 1.7 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 CCD24674.1 - 2.7e-23 81.5 3.2 5.6e-23 80.5 1.8 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus HSCB_C PF07743.8 CCD24675.1 - 8.5e-18 64.5 7.0 1.7e-17 63.6 2.0 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 CCD24675.1 - 1.2e-12 47.3 0.4 1.2e-12 47.3 0.3 2.1 2 0 0 2 2 2 1 DnaJ domain DUF39 PF01837.11 CCD24675.1 - 0.2 10.2 0.8 0.29 9.7 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF39 CK_II_beta PF01214.13 CCD24676.1 - 2.5e-73 245.5 1.2 5.6e-73 244.3 0.9 1.5 1 1 0 1 1 1 1 Casein kinase II regulatory subunit DUF2890 PF11081.3 CCD24676.1 - 0.2 11.6 3.2 0.33 10.9 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CHD5 PF04420.9 CCD24677.1 - 2.4e-48 163.8 4.9 3.2e-48 163.4 3.4 1.1 1 0 0 1 1 1 1 CHD5-like protein DDE_Tnp_2 PF04693.7 CCD24677.1 - 0.0062 15.5 0.5 0.0086 15.1 0.4 1.2 1 0 0 1 1 1 1 Archaeal putative transposase ISC1217 DUF16 PF01519.11 CCD24677.1 - 0.32 11.2 5.5 1.1 9.5 2.6 2.2 2 1 0 2 2 2 0 Protein of unknown function DUF16 DivIC PF04977.10 CCD24677.1 - 1.5 8.3 9.2 0.71 9.3 2.2 2.4 1 1 1 2 2 2 0 Septum formation initiator Atg14 PF10186.4 CCD24677.1 - 1.6 7.6 7.1 2.3 7.1 4.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 NYD-SP28_assoc PF14775.1 CCD24677.1 - 1.6 8.4 7.4 30 4.4 5.1 2.4 1 1 0 1 1 1 0 Sperm tail C-terminal domain STT3 PF02516.9 CCD24678.1 - 3.1e-134 448.5 50.1 2.3e-133 445.7 34.7 1.9 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit IncA PF04156.9 CCD24678.1 - 1.1 8.8 2.7 2.4 7.6 1.9 1.5 1 0 0 1 1 1 0 IncA protein FYVE PF01363.16 CCD24679.1 - 1.9e-14 53.2 10.4 4.4e-14 52.1 7.2 1.7 1 0 0 1 1 1 1 FYVE zinc finger Med3 PF11593.3 CCD24682.1 - 3e-74 250.5 45.7 4.3e-74 250.0 31.7 1.2 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal DUF3682 PF12446.3 CCD24682.1 - 0.0025 18.1 16.6 0.0025 18.1 11.5 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF3682) RPW8 PF05659.6 CCD24682.1 - 0.0067 15.9 0.9 0.64 9.5 0.0 2.3 1 1 1 2 2 2 2 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF3464 PF11947.3 CCD24682.1 - 0.18 11.2 5.9 0.58 9.6 4.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) PAT1 PF09770.4 CCD24682.1 - 0.3 9.2 29.4 0.41 8.8 20.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 CCD24682.1 - 0.74 9.2 10.7 1.4 8.3 7.4 1.5 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Glyco_hydro_63 PF03200.11 CCD24683.1 - 4.8e-218 725.8 7.8 1.8e-217 724.0 5.4 1.7 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 CCD24683.1 - 9.4e-05 21.2 0.0 0.00017 20.4 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Bac_rhamnosid PF05592.6 CCD24683.1 - 0.092 10.9 0.0 0.4 8.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase Suf PF05843.9 CCD24684.1 - 0.17 11.5 8.1 0.25 11.0 5.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) vMSA PF00695.14 CCD24684.1 - 4 6.5 14.9 6.6 5.8 10.3 1.4 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Ribosomal_L7Ae PF01248.21 CCD24685.1 - 4.8e-24 83.6 0.1 5.3e-24 83.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L24e PF01246.15 CCD24686.1 - 1.7e-34 117.4 0.4 1.7e-34 117.4 0.3 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e PVL_ORF50 PF07768.6 CCD24686.1 - 1.2 9.1 9.3 1.6 8.7 6.5 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family ATP-synt_E PF05680.7 CCD24686.1 - 2.3 8.2 11.0 0.67 9.9 5.1 1.8 2 0 0 2 2 2 0 ATP synthase E chain TBPIP PF07106.8 CCD24688.1 - 2.4e-10 40.2 8.0 2.8e-10 40.0 5.5 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 CCD24688.1 - 0.045 12.7 5.8 0.054 12.5 4.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TMPIT PF07851.8 CCD24688.1 - 0.065 12.2 2.8 0.083 11.9 1.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2203 PF09969.4 CCD24688.1 - 0.085 13.0 1.8 0.11 12.6 0.6 1.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Caps_synth_GfcC PF06251.6 CCD24688.1 - 0.087 11.9 0.2 0.1 11.7 0.1 1.1 1 0 0 1 1 1 0 Capsule biosynthesis GfcC GAT PF03127.9 CCD24688.1 - 0.1 12.5 3.9 0.15 12.0 2.7 1.2 1 0 0 1 1 1 0 GAT domain Orbi_VP5 PF00901.12 CCD24688.1 - 0.32 9.1 3.6 0.37 8.9 2.5 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF342 PF03961.8 CCD24688.1 - 0.97 7.7 4.4 1.2 7.5 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Chordopox_L2 PF05803.7 CCD24688.1 - 1.2 8.7 3.6 0.87 9.2 0.6 2.0 1 1 1 2 2 2 0 Chordopoxvirus L2 protein IncA PF04156.9 CCD24688.1 - 4.8 6.7 7.7 7 6.1 5.3 1.2 1 0 0 1 1 1 0 IncA protein zf-H2C2_2 PF13465.1 CCD24689.1 - 3.6e-08 33.2 12.0 0.0003 20.9 0.6 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CCD24689.1 - 1.3e-05 25.2 11.8 0.029 14.7 0.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD24689.1 - 0.0013 18.9 12.0 0.16 12.3 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCD24689.1 - 0.29 11.0 3.4 3.5 7.6 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Ecl1 PF12855.2 CCD24690.1 - 8.7e-15 53.7 4.3 2.5e-14 52.2 3.0 1.8 1 1 0 1 1 1 1 Life-span regulatory factor DUF3612 PF12268.3 CCD24690.1 - 0.032 14.0 0.7 0.044 13.5 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3612) zf-FCS PF06467.9 CCD24690.1 - 0.033 13.8 1.5 0.093 12.3 1.0 1.8 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF2116 PF09889.4 CCD24690.1 - 0.3 10.8 2.2 0.68 9.7 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Pex14_N PF04695.8 CCD24690.1 - 1.7 8.6 10.0 0.48 10.4 1.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SNARE PF05739.14 CCD24691.1 - 0.00026 20.5 2.9 0.00026 20.5 2.0 4.6 5 0 0 5 5 5 1 SNARE domain NUC153 PF08159.7 CCD24692.1 - 2.3e-13 49.4 4.5 6.3e-13 48.0 3.1 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 CCD24692.1 - 0.046 13.6 0.0 4.8 7.2 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat Chloroplast_duf PF14476.1 CCD24693.1 - 0.88 8.3 3.7 2.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Petal formation-expressed Isochorismatase PF00857.15 CCD24694.1 - 2.9e-27 95.7 0.0 4.3e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Gly_transf_sug PF04488.10 CCD24695.1 - 1.7e-14 54.0 0.2 5.5e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Ras PF00071.17 CCD24696.1 - 2.2e-50 170.1 0.0 2.9e-50 169.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD24696.1 - 7e-19 68.4 0.1 1.6e-18 67.3 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCD24696.1 - 2.1e-08 33.5 0.1 2.8e-08 33.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCD24696.1 - 6.4e-08 32.2 0.1 1.2e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCD24696.1 - 0.004 17.1 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RESP18 PF14948.1 CCD24696.1 - 0.33 11.0 5.8 0.29 11.2 2.2 2.0 1 1 1 2 2 2 0 RESP18 domain AAA_22 PF13401.1 CCD24696.1 - 0.37 10.9 1.8 4.4 7.4 0.5 2.6 2 1 0 2 2 2 0 AAA domain ALAD PF00490.16 CCD24697.1 - 1.1e-116 389.3 0.0 1.3e-116 389.0 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Pyridox_oxase_2 PF12766.2 CCD24698.1 - 8.1e-30 103.0 0.2 1.5e-29 102.2 0.1 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase VID27 PF08553.5 CCD24698.1 - 0.43 8.7 5.4 0.53 8.4 3.8 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Nop14 PF04147.7 CCD24698.1 - 0.81 7.5 7.9 0.94 7.3 5.5 1.1 1 0 0 1 1 1 0 Nop14-like family DARPP-32 PF05395.7 CCD24698.1 - 8.6 6.4 8.4 13 5.9 5.8 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Aminotran_3 PF00202.16 CCD24699.1 - 1.1e-83 280.9 0.0 1.3e-83 280.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ATP-synt_F PF01990.12 CCD24700.1 - 8.1e-30 103.0 0.1 9.3e-30 102.8 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 CCD24700.1 - 0.025 13.5 0.0 0.026 13.4 0.0 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Transcrip_reg PF01709.15 CCD24701.1 - 2.2e-53 180.7 6.7 5.1e-53 179.5 4.7 1.5 1 1 0 1 1 1 1 Transcriptional regulator Mid2 PF04478.7 CCD24702.1 - 1.2e-55 187.2 1.3 1.2e-55 187.2 0.9 4.5 2 2 2 5 5 5 1 Mid2 like cell wall stress sensor Thg1 PF04446.7 CCD24704.1 - 3.9e-46 156.0 0.5 5.1e-46 155.6 0.3 1.1 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.1 CCD24704.1 - 2.9e-36 123.8 0.2 5.7e-36 122.8 0.2 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain Ribosomal_S25 PF03297.10 CCD24706.1 - 4.8e-44 148.7 5.7 5.3e-44 148.5 3.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 CCD24706.1 - 0.00028 20.5 0.1 0.00043 19.9 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_CodY PF08222.6 CCD24706.1 - 0.03 13.6 0.1 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain RPA_C PF08784.6 CCD24706.1 - 0.058 13.8 0.0 0.078 13.3 0.0 1.1 1 0 0 1 1 1 0 Replication protein A C terminal HTH_DeoR PF08220.7 CCD24706.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TAF4 PF05236.9 CCD24706.1 - 1.1 8.4 5.4 1.3 8.2 3.7 1.3 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family AAA PF00004.24 CCD24707.1 - 2.2e-36 124.9 0.0 3.6e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CCD24707.1 - 6.8e-07 29.2 0.0 1.4e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCD24707.1 - 1.2e-06 28.6 0.4 0.00046 20.3 0.1 3.2 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 CCD24707.1 - 5.8e-06 26.0 0.5 9.7e-05 22.1 0.3 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CCD24707.1 - 1.1e-05 24.5 0.0 4.5e-05 22.6 0.0 1.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCD24707.1 - 1.2e-05 25.3 0.3 0.00045 20.2 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 CCD24707.1 - 1.3e-05 25.1 0.0 2.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CCD24707.1 - 0.00013 22.7 0.2 0.00047 20.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCD24707.1 - 0.00013 21.4 0.0 0.00027 20.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 CCD24707.1 - 0.00034 20.5 0.0 0.00085 19.2 0.0 1.7 2 0 0 2 2 1 1 AAA domain Bac_DnaA PF00308.13 CCD24707.1 - 0.00065 19.4 0.0 0.00098 18.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Zeta_toxin PF06414.7 CCD24707.1 - 0.001 18.2 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 CCD24707.1 - 0.0011 18.2 0.1 0.0022 17.1 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CCD24707.1 - 0.0018 18.4 0.0 0.0044 17.1 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Sigma54_activ_2 PF14532.1 CCD24707.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain NACHT PF05729.7 CCD24707.1 - 0.0019 17.8 0.0 0.0051 16.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 CCD24707.1 - 0.002 17.5 0.5 0.008 15.5 0.1 2.0 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.1 CCD24707.1 - 0.0024 17.5 0.1 0.0047 16.5 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCD24707.1 - 0.0045 17.2 0.0 0.011 16.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CCD24707.1 - 0.0046 16.4 0.5 0.74 9.1 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain KAP_NTPase PF07693.9 CCD24707.1 - 0.009 15.0 0.8 1.6 7.6 0.0 2.9 2 1 1 3 3 3 1 KAP family P-loop domain AAA_28 PF13521.1 CCD24707.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CCD24707.1 - 0.03 13.9 0.6 0.38 10.3 0.0 2.4 2 1 1 3 3 3 0 Archaeal ATPase AAA_19 PF13245.1 CCD24707.1 - 0.031 14.0 0.1 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain KaiC PF06745.8 CCD24707.1 - 0.039 13.0 0.0 0.19 10.8 0.0 1.9 1 1 1 2 2 2 0 KaiC DUF815 PF05673.8 CCD24707.1 - 0.053 12.4 0.0 0.082 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_21 PF13304.1 CCD24707.1 - 0.056 13.3 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain DNA_topoisoIV PF00521.15 CCD24707.1 - 0.066 12.0 0.0 0.14 10.9 0.0 1.4 1 1 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Sigma54_activat PF00158.21 CCD24707.1 - 0.066 12.6 0.0 0.24 10.8 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 CCD24707.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 CCD24707.1 - 0.093 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 CCD24707.1 - 0.094 11.9 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Rad17 PF03215.10 CCD24707.1 - 0.097 11.3 0.0 0.17 10.5 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 CCD24707.1 - 0.14 11.7 0.0 0.36 10.4 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Evr1_Alr PF04777.8 CCD24708.1 - 2.9e-29 100.8 3.7 2.9e-29 100.8 2.6 1.5 2 0 0 2 2 2 1 Erv1 / Alr family Alba PF01918.16 CCD24709.1 - 4.9e-05 22.8 0.0 8.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Alba DUF3978 PF13123.1 CCD24709.1 - 0.014 14.7 0.6 0.014 14.7 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3978) zf-PARP PF00645.13 CCD24709.1 - 0.084 13.1 0.5 0.18 12.0 0.0 1.8 2 1 0 2 2 2 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Ribosomal_L10 PF00466.15 CCD24710.1 - 9.2e-26 89.6 0.2 1.6e-25 88.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CCD24710.1 - 1.1e-17 64.1 6.4 1.5e-17 63.7 1.8 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Abhydrolase_6 PF12697.2 CCD24711.1 - 8.5e-25 87.9 0.0 2e-24 86.7 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD24711.1 - 2.8e-16 59.7 0.0 4.2e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCD24711.1 - 7.9e-10 38.6 0.0 1.8e-09 37.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CCD24711.1 - 2.8e-06 27.0 0.1 1.6e-05 24.5 0.0 2.0 1 1 1 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.3 CCD24711.1 - 0.0051 16.6 0.1 0.0097 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 CCD24711.1 - 0.038 13.4 0.1 0.089 12.1 0.1 1.7 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Glucan_synthase PF02364.10 CCD24712.1 - 0 1356.1 0.0 0 1355.4 0.0 1.4 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCD24712.1 - 1.4e-38 131.3 1.1 2.6e-38 130.5 0.1 2.0 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TIM21 PF08294.6 CCD24713.1 - 4.8e-57 191.6 0.0 6.8e-57 191.1 0.0 1.2 1 0 0 1 1 1 1 TIM21 KOW PF00467.24 CCD24714.1 - 0.0012 18.4 0.4 0.0012 18.4 0.3 1.9 2 1 0 2 2 2 1 KOW motif 6PF2K PF01591.13 CCD24715.1 - 1.7e-54 184.2 4.1 2.5e-54 183.7 2.9 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCD24715.1 - 2.2e-12 47.3 0.5 7.1e-12 45.7 0.1 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CCD24715.1 - 0.00066 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCD24715.1 - 0.018 14.2 0.5 0.036 13.2 0.3 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PAP2 PF01569.16 CCD24716.1 - 2.2e-19 69.4 2.6 3.7e-19 68.6 1.8 1.5 1 1 0 1 1 1 1 PAP2 superfamily MFS_1 PF07690.11 CCD24716.1 - 0.018 13.7 8.2 0.025 13.3 5.7 1.3 1 0 0 1 1 1 0 Major Facilitator Superfamily UPF0542 PF15086.1 CCD24716.1 - 0.37 10.5 0.1 0.37 10.5 0.1 2.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0542 Apq12 PF12716.2 CCD24716.1 - 0.49 10.1 7.4 5.8 6.6 0.6 3.1 2 1 0 2 2 2 0 Nuclear pore assembly and biogenesis ACBP PF00887.14 CCD24717.1 - 1.9e-31 107.5 1.8 2.1e-31 107.4 1.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 CCD24717.1 - 0.0095 16.1 0.2 0.07 13.3 0.0 1.9 1 1 1 2 2 2 1 FERM central domain ORMDL PF04061.9 CCD24718.1 - 2.2e-58 195.6 6.3 2.8e-58 195.2 4.4 1.1 1 0 0 1 1 1 1 ORMDL family PI3K_C2 PF00792.19 CCD24718.1 - 0.035 13.8 0.0 0.092 12.5 0.0 1.7 1 0 0 1 1 1 0 Phosphoinositide 3-kinase C2 RNR_inhib PF08591.5 CCD24718.1 - 0.27 12.1 2.4 0.43 11.5 1.6 1.3 1 0 0 1 1 1 0 Ribonucleotide reductase inhibitor Pkinase PF00069.20 CCD24719.1 - 5e-73 245.4 0.0 6.2e-73 245.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24719.1 - 3.5e-34 118.0 0.2 6.2e-34 117.2 0.1 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD24719.1 - 3.4e-06 26.2 0.0 5.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCD24719.1 - 0.002 17.2 0.1 0.017 14.2 0.1 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD24719.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 CCD24719.1 - 0.023 14.0 0.1 0.037 13.3 0.1 1.3 1 0 0 1 1 1 0 RIO1 family DUF2439 PF10382.4 CCD24721.1 - 1.7e-19 69.7 0.1 4e-19 68.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Transaldolase PF00923.14 CCD24722.1 - 1.1e-90 303.6 1.4 1.3e-90 303.4 1.0 1.0 1 0 0 1 1 1 1 Transaldolase zf-C2H2 PF00096.21 CCD24723.1 - 0.00012 22.1 12.8 0.012 15.9 0.1 4.4 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD24723.1 - 0.00027 21.0 16.2 0.053 13.8 0.1 4.1 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD24723.1 - 0.36 11.2 17.5 7.7 7.0 1.3 4.9 4 1 0 4 4 4 0 Zinc-finger double domain Pkinase PF00069.20 CCD24725.1 - 7.6e-53 179.2 0.3 8.9e-53 179.0 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24725.1 - 7.7e-28 97.2 0.0 1.2e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCD24725.1 - 2.9e-07 30.4 0.0 0.012 15.3 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 CCD24725.1 - 3.9e-07 29.3 0.0 8.6e-07 28.1 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCD24725.1 - 0.018 14.0 0.0 0.034 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CCD24725.1 - 0.036 13.6 0.1 0.066 12.7 0.0 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase RXT2_N PF08595.6 CCD24725.1 - 0.089 12.5 0.7 0.16 11.7 0.0 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal GDE_C PF06202.9 CCD24726.1 - 0.073 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase DUF960 PF06124.6 CCD24726.1 - 0.27 11.5 1.7 6.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) Bromodomain PF00439.20 CCD24727.1 - 7.6e-27 93.0 7.9 2.2e-14 53.1 1.2 2.7 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 CCD24727.1 - 6.1e-22 77.6 0.0 1.5e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 BAH domain Folliculin PF11704.3 CCD24728.1 - 2.3e-51 173.6 1.3 2.9e-51 173.4 0.9 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport EF-hand_6 PF13405.1 CCD24729.1 - 5.8e-08 31.9 0.3 0.047 13.5 0.0 4.3 3 1 1 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 CCD24729.1 - 2e-07 31.0 1.2 0.0059 16.7 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CCD24729.1 - 3.7e-07 28.9 0.0 2.6 7.5 0.0 4.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 CCD24729.1 - 0.002 17.6 0.2 3.2 7.4 0.0 3.8 3 1 1 4 4 4 1 EF-hand domain pair SEN1_N PF12726.2 CCD24729.1 - 0.012 13.6 0.1 0.018 13.0 0.1 1.1 1 0 0 1 1 1 0 SEN1 N terminal EF-hand_5 PF13202.1 CCD24729.1 - 0.049 12.9 0.2 42 3.7 0.0 3.9 4 0 0 4 4 4 0 EF hand FAM75 PF14650.1 CCD24729.1 - 3.7 6.8 15.9 6 6.1 11.0 1.3 1 0 0 1 1 1 0 FAM75 family Septin PF00735.13 CCD24730.1 - 1.1e-86 290.3 2.9 2e-86 289.5 2.0 1.4 1 0 0 1 1 1 1 Septin AAA_24 PF13479.1 CCD24730.1 - 0.00061 19.4 0.8 0.0023 17.5 0.1 2.2 2 1 0 3 3 2 1 AAA domain DUF258 PF03193.11 CCD24730.1 - 0.00074 18.7 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCD24730.1 - 0.00075 18.9 0.6 0.39 10.1 0.1 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain T2SE PF00437.15 CCD24730.1 - 0.00079 18.4 0.1 0.0014 17.6 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein MMR_HSR1 PF01926.18 CCD24730.1 - 0.0017 18.3 0.1 0.0048 16.8 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 CCD24730.1 - 0.003 17.0 0.0 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family Miro PF08477.8 CCD24730.1 - 0.003 18.0 0.2 0.0076 16.7 0.1 1.9 1 1 0 1 1 1 1 Miro-like protein Sigma54_activat PF00158.21 CCD24730.1 - 0.0044 16.4 0.1 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_10 PF12846.2 CCD24730.1 - 0.005 16.3 0.0 0.01 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 CCD24730.1 - 0.0053 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain G-alpha PF00503.15 CCD24730.1 - 0.0069 15.1 0.2 0.0069 15.1 0.1 2.9 2 1 0 3 3 3 1 G-protein alpha subunit DNA_pol3_delta2 PF13177.1 CCD24730.1 - 0.018 14.7 0.5 0.018 14.7 0.3 2.0 2 0 0 2 2 2 0 DNA polymerase III, delta subunit AAA_22 PF13401.1 CCD24730.1 - 0.021 14.9 0.3 0.059 13.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCD24730.1 - 0.024 14.9 2.1 0.039 14.2 0.5 1.9 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CCD24730.1 - 0.026 14.0 0.1 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.11 CCD24730.1 - 0.044 12.8 0.4 0.044 12.8 0.3 2.2 2 0 0 2 2 2 0 AIG1 family ATP_bind_1 PF03029.12 CCD24730.1 - 0.046 13.2 0.2 12 5.3 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 CCD24730.1 - 0.06 13.1 3.0 0.56 10.0 0.2 2.8 2 1 1 3 3 3 0 Dynamin family AAA PF00004.24 CCD24730.1 - 0.076 13.2 0.1 0.26 11.4 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CCD24730.1 - 0.096 12.9 1.1 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Sigma54_activ_2 PF14532.1 CCD24730.1 - 0.11 12.4 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 CCD24730.1 - 0.19 11.1 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CCD24730.1 - 0.52 11.1 4.1 5.1 7.9 2.8 2.8 1 1 0 1 1 1 0 AAA domain Cep57_CLD PF14073.1 CCD24730.1 - 0.54 10.0 6.8 0.064 13.0 1.4 1.9 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 AAA_14 PF13173.1 CCD24730.1 - 0.7 9.7 0.0 0.7 9.7 0.0 3.0 3 1 0 3 3 3 0 AAA domain FA_hydroxylase PF04116.8 CCD24731.1 - 1.6e-15 57.4 24.5 1.6e-15 57.4 13.9 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FDC-SP PF15215.1 CCD24731.1 - 0.017 15.3 1.0 0.05 13.9 0.7 1.8 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide GATase_5 PF13507.1 CCD24732.1 - 2.8e-97 324.6 0.1 4.3e-97 324.0 0.1 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 CCD24732.1 - 1.7e-44 151.5 0.1 4e-25 88.6 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CCD24732.1 - 7.1e-23 80.6 0.3 3.1e-22 78.6 0.0 2.3 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain DUF2462 PF09495.5 CCD24733.1 - 4.2e-20 72.2 13.1 5.3e-20 71.9 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) 60KD_IMP PF02096.15 CCD24734.1 - 4.4e-17 62.3 10.9 1.7e-16 60.5 7.6 1.8 1 1 0 1 1 1 1 60Kd inner membrane protein Spt4 PF06093.8 CCD24735.1 - 1.3e-24 85.8 0.0 1.6e-24 85.5 0.0 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger MFS_1 PF07690.11 CCD24736.1 - 9.1e-18 64.0 17.0 9.1e-18 64.0 11.8 1.9 1 1 0 2 2 2 1 Major Facilitator Superfamily Osteopontin PF00865.13 CCD24736.1 - 0.0011 18.2 4.8 0.0017 17.6 3.4 1.2 1 0 0 1 1 1 1 Osteopontin DUF1212 PF06738.7 CCD24736.1 - 0.33 10.4 2.5 0.8 9.1 1.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Ribosomal_S8 PF00410.14 CCD24737.1 - 1.8e-27 95.7 0.1 2.4e-27 95.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 zf-H2C2_2 PF13465.1 CCD24738.1 - 0.00012 22.2 1.9 0.00012 22.2 1.3 3.7 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CCD24738.1 - 0.00028 21.0 11.5 0.14 12.5 1.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD24738.1 - 0.0073 16.5 9.7 0.08 13.3 1.6 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger Arrestin_C PF02752.17 CCD24739.1 - 2.6e-19 69.7 0.7 2.6e-19 69.7 0.5 3.4 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCD24739.1 - 3.9e-07 29.9 0.1 0.00019 21.2 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain DUF3446 PF11928.3 CCD24739.1 - 7.7 6.7 21.2 0.93 9.7 3.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3446) Pribosyltran_N PF13793.1 CCD24740.1 - 6e-40 135.6 0.1 8.9e-39 131.8 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CCD24740.1 - 2.4e-38 131.7 1.3 4.1e-30 104.8 0.2 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CCD24740.1 - 2.2e-08 33.8 0.3 0.00085 19.0 0.1 2.5 2 0 0 2 2 2 2 Phosphoribosyl transferase domain Vps39_1 PF10366.4 CCD24741.1 - 1.9e-24 85.7 2.7 1.1e-23 83.2 0.1 3.4 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 CCD24741.1 - 6.6e-10 39.1 1.1 1.9e-09 37.6 0.4 2.2 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Rxt3 PF08642.5 CCD24742.1 - 5.4e-26 91.0 0.0 1e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 Ribosomal_L31e PF01198.14 CCD24743.1 - 1.6e-15 56.5 0.2 1.9e-15 56.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e BRE1 PF08647.6 CCD24744.1 - 5.2e-24 84.0 12.8 5.2e-24 84.0 8.9 6.7 4 2 2 7 7 6 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.1 CCD24744.1 - 1.6e-06 27.6 11.1 2.9e-06 26.8 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD24744.1 - 2.8e-06 27.2 13.4 5.5e-06 26.3 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCD24744.1 - 2.9e-05 23.7 13.3 5.8e-05 22.7 9.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCD24744.1 - 5.1e-05 22.8 13.9 0.00011 21.8 9.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCD24744.1 - 0.0013 18.4 11.2 0.0025 17.6 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 CCD24744.1 - 0.008 15.9 3.8 0.02 14.6 2.6 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CCD24744.1 - 0.01 15.5 8.0 0.053 13.2 5.5 2.4 1 0 0 1 1 1 0 RING-type zinc-finger DivIC PF04977.10 CCD24744.1 - 0.012 15.1 1.0 0.012 15.1 0.7 7.3 4 2 3 7 7 7 0 Septum formation initiator Prok-RING_4 PF14447.1 CCD24744.1 - 0.02 14.4 5.4 0.042 13.3 3.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 CCD24744.1 - 0.63 9.6 11.5 1.3 8.6 8.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 CCD24744.1 - 2.5 8.0 10.5 6.3 6.7 7.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FYVE PF01363.16 CCD24744.1 - 8.7 6.3 13.3 74 3.3 9.0 2.4 1 1 1 2 2 2 0 FYVE zinc finger DUF1765 PF08578.5 CCD24745.1 - 6.1e-14 52.1 11.9 6.1e-14 52.1 8.3 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF1765) zf-C2H2_4 PF13894.1 CCD24746.1 - 1.8e-05 24.7 12.6 0.058 13.7 0.3 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCD24746.1 - 0.00032 20.7 1.5 0.16 12.1 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CCD24746.1 - 0.064 13.5 17.0 0.17 12.2 0.8 3.2 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2 PF00096.21 CCD24746.1 - 0.22 11.9 24.6 0.11 12.9 1.2 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type Bap31 PF05529.7 CCD24747.1 - 4.5e-44 150.2 2.3 4.5e-44 150.2 1.6 1.4 2 0 0 2 2 2 1 B-cell receptor-associated protein 31-like DUF2254 PF10011.4 CCD24747.1 - 0.02 13.4 0.4 0.77 8.1 0.0 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) DUF4199 PF13858.1 CCD24747.1 - 1.7 8.5 7.1 0.32 10.9 0.2 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF4199) Iso_dh PF00180.15 CCD24750.1 - 2e-69 234.1 0.0 2.3e-69 233.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pex19 PF04614.7 CCD24751.1 - 1.1e-42 146.4 21.7 5.2e-42 144.1 15.1 1.9 1 1 0 1 1 1 1 Pex19 protein family Sec5 PF15469.1 CCD24751.1 - 9.7 5.8 18.6 1.2 8.8 9.1 2.3 2 2 1 3 3 3 0 Exocyst complex component Sec5 UQ_con PF00179.21 CCD24752.1 - 3.5e-44 149.6 0.2 4e-44 149.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCD24752.1 - 0.00012 21.7 0.0 0.00014 21.5 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCD24752.1 - 0.28 11.0 3.2 0.54 10.1 2.0 1.8 1 1 0 1 1 1 0 RWD domain Zein PF01559.11 CCD24753.1 - 0.085 12.1 0.7 0.18 11.0 0.5 1.5 1 0 0 1 1 1 0 Zein seed storage protein Ribosomal_S14 PF00253.16 CCD24754.1 - 1.4e-17 62.7 4.9 1.5e-17 62.6 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 CCD24754.1 - 0.046 13.4 0.2 0.053 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) Prim_Zn_Ribbon PF08273.7 CCD24754.1 - 0.062 13.3 2.0 0.95 9.5 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF2296 PF10058.4 CCD24754.1 - 0.16 11.7 1.7 8.2 6.2 1.8 2.1 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) RNA_POL_M_15KD PF02150.11 CCD24754.1 - 0.5 10.0 2.7 6.2 6.6 0.2 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Rad52_Rad22 PF04098.10 CCD24755.1 - 3.8e-41 140.3 5.5 6.9e-41 139.5 3.8 1.4 1 1 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF2634 PF10934.3 CCD24755.1 - 0.047 13.4 0.8 0.19 11.5 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2634) Uso1_p115_head PF04869.9 CCD24756.1 - 3.2e-99 331.6 8.1 1.1e-98 329.8 5.6 2.1 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Tropomyosin_1 PF12718.2 CCD24756.1 - 0.0046 16.7 24.6 0.0046 16.7 17.1 14.8 2 1 14 16 16 16 3 Tropomyosin like Reo_sigmaC PF04582.7 CCD24756.1 - 0.25 10.4 101.1 0.025 13.7 1.5 9.9 2 2 6 10 10 10 0 Reovirus sigma C capsid protein Ank_5 PF13857.1 CCD24757.1 - 9e-18 63.9 0.2 3.2e-06 27.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCD24757.1 - 3.4e-16 59.3 1.5 5e-07 29.9 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCD24757.1 - 4.3e-16 58.9 1.4 2e-07 31.3 0.0 3.5 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CCD24757.1 - 1.9e-13 49.4 3.7 4.3e-06 26.2 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 CCD24757.1 - 8e-13 47.2 2.4 0.00053 19.9 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 CCD24757.1 - 2.3e-08 33.6 1.8 5.9e-08 32.3 0.2 2.6 2 1 0 2 2 2 1 KilA-N domain DUF1192 PF06698.6 CCD24757.1 - 0.044 13.6 1.9 0.14 12.0 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF4446 PF14584.1 CCD24757.1 - 0.067 13.0 1.6 0.17 11.7 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Fib_alpha PF08702.5 CCD24757.1 - 0.31 11.1 3.6 1 9.5 2.5 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family NTP_transferase PF00483.18 CCD24758.1 - 1.8e-49 168.3 0.0 2.3e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CCD24758.1 - 1.5e-10 41.3 0.0 2e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 CCD24758.1 - 3.2e-09 35.8 6.7 1.9e-07 30.2 1.1 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CCD24758.1 - 0.0016 17.9 1.1 0.0016 17.9 0.8 3.1 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 CCD24758.1 - 0.034 13.7 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Cytidylyltransferase FA_hydroxylase PF04116.8 CCD24759.1 - 1.4e-15 57.7 21.3 1.4e-15 57.7 14.7 2.4 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily FDC-SP PF15215.1 CCD24759.1 - 0.0037 17.5 0.5 0.019 15.2 0.3 2.2 1 0 0 1 1 1 1 Follicular dendritic cell secreted peptide MFS_1 PF07690.11 CCD24760.1 - 7.1e-11 41.4 28.6 1.9e-10 39.9 19.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2775 PF10950.3 CCD24761.1 - 0.11 12.6 9.0 0.91 9.7 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2775) DUF2121 PF09894.4 CCD24761.1 - 0.16 11.1 1.5 0.23 10.7 1.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) DUF2475 PF10629.4 CCD24761.1 - 0.71 10.1 4.7 0.6 10.3 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2475) Acyltransferase PF01553.16 CCD24762.1 - 2.2e-34 117.7 0.0 3.4e-34 117.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase DUF4118 PF13493.1 CCD24762.1 - 0.13 12.4 0.9 0.5 10.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) La PF05383.12 CCD24763.1 - 2.6e-23 81.5 0.0 6.5e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 CCD24763.1 - 0.00086 19.2 0.2 0.0018 18.1 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) KRE9 PF05390.6 CCD24764.1 - 8.8e-56 186.8 8.1 1.9e-55 185.7 5.6 1.5 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CCD24764.1 - 1e-09 38.7 0.3 1e-09 38.7 0.2 2.7 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family zf-C2H2 PF00096.21 CCD24765.1 - 0.00088 19.4 1.3 0.00088 19.4 0.9 4.9 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD24765.1 - 0.0015 18.7 1.2 0.0015 18.7 0.8 4.6 4 0 0 4 4 4 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD24765.1 - 0.0022 18.2 2.1 0.0022 18.2 1.4 4.7 4 1 1 5 5 5 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 CCD24765.1 - 0.0045 16.8 8.0 0.0059 16.4 0.1 3.6 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCD24765.1 - 0.0096 16.0 1.8 0.33 11.1 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-RING_3 PF14369.1 CCD24765.1 - 0.02 14.8 4.3 2 8.4 0.2 3.6 3 0 0 3 3 3 0 zinc-finger Rad50_zn_hook PF04423.9 CCD24765.1 - 0.36 10.3 4.2 1.5 8.3 0.1 2.8 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-Di19 PF05605.7 CCD24765.1 - 1.7 8.8 7.8 0.47 10.6 1.8 2.7 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-BED PF02892.10 CCD24766.1 - 2.6e-07 30.2 1.3 2.6e-07 30.2 0.9 2.1 2 0 0 2 2 2 1 BED zinc finger ELO PF01151.13 CCD24767.1 - 4.6e-58 196.4 28.3 5.6e-58 196.1 19.6 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family CNH PF00780.17 CCD24768.1 - 3.5e-77 259.5 0.3 2.9e-76 256.5 0.0 2.3 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 CCD24768.1 - 8.2e-38 129.4 0.0 8.2e-38 129.4 0.0 4.5 4 1 0 5 5 5 1 Pleckstrin homology domain RhoGEF PF00621.15 CCD24768.1 - 9.6e-31 107.0 0.0 9.6e-31 107.0 0.0 2.7 2 1 0 2 2 2 1 RhoGEF domain DEP PF00610.16 CCD24768.1 - 2.1e-12 46.6 0.0 5e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Voldacs PF03517.8 CCD24769.1 - 1.1e-12 47.9 0.1 2.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Orn_Arg_deC_N PF02784.11 CCD24770.1 - 4.9e-77 258.5 0.0 6.7e-77 258.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CCD24770.1 - 1.6e-31 108.4 0.3 1.9e-30 104.9 0.1 2.3 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Rep_fac-A_3 PF08661.6 CCD24770.1 - 0.058 13.3 0.1 0.64 9.9 0.0 2.2 2 0 0 2 2 2 0 Replication factor A protein 3 GATA PF00320.22 CCD24771.1 - 1.3e-08 34.0 9.1 1.3e-08 34.0 6.3 2.1 2 0 0 2 2 2 1 GATA zinc finger ACR_tran PF00873.14 CCD24771.1 - 2.5 5.3 4.8 3.8 4.7 3.3 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Mtr2 PF10429.4 CCD24772.1 - 1.7e-69 232.8 0.2 2e-69 232.6 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 SUR7 PF06687.7 CCD24773.1 - 7.8e-23 81.1 0.2 2.4e-22 79.5 0.2 1.8 1 1 0 1 1 1 1 SUR7/PalI family TFIIA PF03153.8 CCD24773.1 - 0.054 13.3 3.5 0.7 9.7 0.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ABC_membrane_2 PF06472.10 CCD24774.1 - 1.2e-67 228.0 10.2 1.2e-66 224.7 7.1 2.0 1 1 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CCD24774.1 - 3.2e-19 69.5 0.2 5.8e-17 62.2 0.1 2.6 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCD24774.1 - 2e-06 28.0 0.3 2e-06 28.0 0.2 3.7 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 CCD24774.1 - 0.018 14.5 0.0 0.041 13.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 CCD24774.1 - 0.029 13.5 0.0 0.1 11.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCD24774.1 - 0.035 14.0 0.2 0.097 12.6 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain Mo25 PF08569.6 CCD24775.1 - 1.1e-111 373.1 17.2 2.4e-111 372.0 11.9 1.5 1 1 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 CCD24775.1 - 0.011 15.9 0.0 0.3 11.3 0.0 2.4 2 0 0 2 2 2 0 HEAT repeats Bromodomain PF00439.20 CCD24776.1 - 2.9e-27 94.3 2.1 5.7e-27 93.4 1.5 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 CCD24776.1 - 5.5e-09 36.0 0.2 1.1e-08 35.0 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCD24776.1 - 1.6e-08 34.4 0.0 2.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCD24776.1 - 0.0013 18.8 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCD24776.1 - 0.0037 17.2 0.1 0.0084 16.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF572 PF04502.8 CCD24776.1 - 0.27 10.4 5.0 0.38 9.9 3.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) EF-hand_1 PF00036.27 CCD24777.1 - 4.1e-24 81.9 14.1 2.6e-05 23.1 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCD24777.1 - 8.1e-20 70.7 3.8 3.4e-10 39.8 1.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCD24777.1 - 3.7e-19 66.8 5.8 0.00033 20.3 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 CCD24777.1 - 7.2e-17 59.8 14.8 0.0003 19.9 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 CCD24777.1 - 5.2e-11 41.9 16.2 0.0015 18.0 0.4 4.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 CCD24777.1 - 6.9e-07 28.9 9.3 0.0037 16.9 0.1 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CCD24777.1 - 1.2e-05 25.3 0.0 0.028 14.4 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CCD24777.1 - 0.0013 18.6 0.0 1.2 9.1 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain Diphthamide_syn PF01866.12 CCD24778.1 - 1.5e-43 149.2 0.1 3.9e-21 75.5 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein LRR_4 PF12799.2 CCD24779.1 - 6.1e-37 124.6 50.3 4.9e-10 38.7 3.3 7.6 5 3 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCD24779.1 - 1.5e-20 72.7 41.3 7.9e-10 38.3 2.3 6.0 2 1 4 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 CCD24779.1 - 6.3e-11 40.7 35.4 0.54 10.4 0.4 11.5 10 2 1 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 CCD24779.1 - 1.8e-08 33.5 35.4 0.16 12.0 1.4 11.0 9 3 3 12 12 12 4 Leucine Rich repeat LRR_7 PF13504.1 CCD24779.1 - 2.4e-08 32.8 20.7 0.71 10.3 0.2 9.6 9 1 0 9 9 9 3 Leucine rich repeat LRR_9 PF14580.1 CCD24779.1 - 9.3e-08 31.8 19.4 2.2e-05 24.0 3.4 3.4 1 1 2 3 3 3 2 Leucine-rich repeat DUF3744 PF12558.3 CCD24779.1 - 0.023 15.1 17.9 0.094 13.1 0.7 4.7 3 2 2 5 5 5 0 ATP-binding cassette cobalt transporter tRNA-synt_2b PF00587.20 CCD24780.1 - 7.1e-44 149.4 0.0 9.9e-44 148.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCD24780.1 - 1.4e-17 63.3 0.0 2.4e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain DUF3893 PF13032.1 CCD24780.1 - 0.074 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3893) CHCH PF06747.8 CCD24781.1 - 5.9e-05 22.8 3.1 0.00013 21.7 2.2 1.6 1 0 0 1 1 1 1 CHCH domain Longin PF13774.1 CCD24782.1 - 1.7e-16 59.5 0.0 2.8e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CCD24782.1 - 2.4e-15 55.8 1.2 4.1e-15 55.1 0.8 1.3 1 0 0 1 1 1 1 Synaptobrevin Cyclase_polyket PF04673.7 CCD24782.1 - 0.026 14.5 0.3 0.21 11.6 0.0 2.2 1 1 2 3 3 3 0 Polyketide synthesis cyclase UPF0449 PF15136.1 CCD24782.1 - 0.032 14.4 0.7 0.051 13.7 0.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Tbf5 PF06331.7 CCD24782.1 - 0.071 12.8 0.5 0.13 12.0 0.3 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Nsp1_C PF05064.8 CCD24782.1 - 0.3 10.7 5.3 2.2 7.9 0.3 2.7 1 1 2 3 3 3 0 Nsp1-like C-terminal region FMN_dh PF01070.13 CCD24783.1 - 6.6e-119 396.9 0.0 8e-119 396.6 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCD24783.1 - 1.9e-22 78.8 0.0 5.6e-22 77.3 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CCD24783.1 - 9.8e-09 34.5 0.0 1.9e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 CCD24783.1 - 3.1e-06 26.5 0.0 4.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCD24783.1 - 0.0016 17.3 1.6 0.019 13.8 0.1 2.5 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 CCD24783.1 - 0.012 14.8 0.3 8.8 5.5 0.0 3.0 3 0 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.9 CCD24783.1 - 0.047 12.7 0.0 1.9 7.5 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG FMN_dh PF01070.13 CCD24784.1 - 6e-120 400.3 0.0 7.4e-120 400.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCD24784.1 - 7.6e-21 73.7 0.0 1.6e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CCD24784.1 - 8.9e-09 34.7 0.0 1.5e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 CCD24784.1 - 9.1e-05 21.7 0.0 0.00015 21.0 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCD24784.1 - 0.0013 17.7 1.0 0.02 13.8 0.1 2.4 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 CCD24784.1 - 0.049 12.8 0.2 9 5.4 0.0 2.8 3 0 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.9 CCD24784.1 - 0.081 11.9 0.0 3.4 6.6 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG SPC25 PF06703.6 CCD24785.1 - 7.5e-37 126.3 4.0 8.4e-37 126.2 2.8 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Claudin_2 PF13903.1 CCD24785.1 - 0.082 12.5 0.3 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DDE_Tnp_1 PF01609.16 CCD24785.1 - 0.098 12.1 0.1 0.13 11.7 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain DUF1900 PF08954.6 CCD24786.1 - 1.6e-32 111.8 0.0 3.2e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) WD40 PF00400.27 CCD24786.1 - 2e-23 81.3 3.8 2.1e-06 27.3 0.1 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1899 PF08953.6 CCD24786.1 - 6.2e-22 77.0 0.2 1.2e-21 76.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) Nup160 PF11715.3 CCD24786.1 - 1.6e-05 23.3 0.1 0.00095 17.4 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DASH_Dad3 PF08656.5 CCD24786.1 - 0.0066 16.1 0.5 0.018 14.7 0.3 1.7 1 0 0 1 1 1 1 DASH complex subunit Dad3 Coatomer_b_Cpla PF14806.1 CCD24786.1 - 0.034 13.8 0.2 0.11 12.1 0.2 1.9 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform eIF2A PF08662.6 CCD24786.1 - 0.037 13.7 1.5 2 8.0 0.0 3.4 3 1 1 4 4 4 0 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CCD24786.1 - 0.075 11.3 0.1 0.18 10.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome D1 heme domain Nup54 PF13874.1 CCD24786.1 - 0.11 12.1 2.7 0.074 12.7 0.3 1.8 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 IMPDH PF00478.20 CCD24787.1 - 1.4e-141 471.5 1.7 1.6e-141 471.2 1.2 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CCD24787.1 - 8e-17 60.7 0.0 4.2e-08 32.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 CCD24787.1 - 3.4e-08 33.0 2.3 0.00036 19.7 1.0 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 CCD24787.1 - 8.1e-08 31.4 1.3 2.7e-07 29.7 0.9 1.8 1 1 0 1 1 1 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CCD24787.1 - 0.0016 17.7 0.9 0.011 15.0 0.7 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 CCD24787.1 - 0.049 12.7 3.1 0.1 11.6 0.8 2.1 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG DUF1273 PF06908.6 CCD24787.1 - 0.067 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) EAL PF00563.15 CCD24787.1 - 0.099 12.1 0.1 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 EAL domain RNR_inhib PF08591.5 CCD24788.1 - 9.1e-05 23.2 0.2 0.00011 22.9 0.1 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Osmo_CC PF08946.5 CCD24788.1 - 0.07 13.1 0.1 0.18 11.8 0.1 1.7 1 0 0 1 1 1 0 Osmosensory transporter coiled coil PBP PF01161.15 CCD24790.1 - 2.8e-24 85.6 0.1 3.3e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein cNMP_binding PF00027.24 CCD24791.1 - 1.3e-37 127.4 0.4 3.9e-17 61.8 0.0 5.1 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.17 CCD24791.1 - 1.2e-17 64.5 4.3 2e-16 60.5 2.0 3.1 2 1 0 2 2 2 1 Patatin-like phospholipase OGG_N PF07934.7 CCD24792.1 - 6.1e-20 71.3 0.3 1.2e-19 70.4 0.2 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CCD24792.1 - 3.1e-19 69.2 0.0 5.5e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF1313 PF07011.6 CCD24792.1 - 0.11 12.1 0.9 7.7 6.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1313) PIF1 PF05970.9 CCD24793.1 - 9e-75 251.8 1.2 4.5e-57 193.6 0.1 2.2 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 CCD24793.1 - 7.2e-12 45.2 0.0 1.3e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCD24793.1 - 3e-05 24.1 0.0 8.3e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 CCD24793.1 - 0.00086 17.1 0.2 0.014 13.1 0.0 2.1 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 CCD24793.1 - 0.0027 17.8 0.0 0.023 14.8 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CCD24793.1 - 0.016 14.9 0.2 0.034 13.8 0.2 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF2075 PF09848.4 CCD24793.1 - 0.043 12.7 0.1 0.46 9.3 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 CCD24793.1 - 0.045 12.9 0.2 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_32 PF13654.1 CCD24793.1 - 0.047 12.3 0.0 0.18 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Helicase_RecD PF05127.9 CCD24793.1 - 0.06 12.9 0.3 0.3 10.7 0.2 2.1 1 1 0 1 1 1 0 Helicase Arch_ATPase PF01637.13 CCD24793.1 - 0.068 12.8 0.4 0.52 9.9 0.3 2.4 1 1 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 CCD24793.1 - 0.071 12.7 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 CCD24793.1 - 0.085 12.8 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RRM_1 PF00076.17 CCD24794.1 - 1.2e-32 111.3 1.7 4.8e-15 54.9 0.0 3.8 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD24794.1 - 6.7e-19 67.6 0.2 3.3e-08 33.3 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD24794.1 - 2.3e-18 65.7 0.2 1.3e-10 40.9 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCD24794.1 - 1.7e-07 30.9 0.0 0.003 17.3 0.0 2.8 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DUF386 PF04074.7 CCD24794.1 - 0.063 12.7 0.5 0.12 11.8 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF386) AAA_2 PF07724.9 CCD24795.1 - 6.1e-47 159.7 0.0 1.7e-45 154.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CCD24795.1 - 4.2e-23 81.9 0.1 9.4e-14 51.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CCD24795.1 - 9.8e-22 76.6 0.6 3.5e-21 74.8 0.4 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CCD24795.1 - 1.5e-15 57.1 0.1 2.3e-07 30.6 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 CCD24795.1 - 7.8e-14 51.3 3.9 1.4e-07 31.3 0.2 4.1 3 0 0 3 3 3 2 Clp amino terminal domain Sigma54_activat PF00158.21 CCD24795.1 - 2.8e-12 46.4 0.1 6.4e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 CCD24795.1 - 1.5e-11 44.6 0.8 0.00032 20.7 0.0 4.5 3 1 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 CCD24795.1 - 2.1e-08 34.3 0.2 0.0055 16.8 0.0 3.4 3 1 0 3 3 2 2 AAA domain AAA_17 PF13207.1 CCD24795.1 - 0.00016 22.5 5.1 0.27 12.0 0.0 4.1 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 CCD24795.1 - 0.00033 19.8 0.0 1.1 8.3 0.0 3.4 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 CCD24795.1 - 0.00061 19.7 0.3 0.011 15.6 0.0 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_18 PF13238.1 CCD24795.1 - 0.001 19.3 0.1 3.1 8.1 0.0 3.6 3 0 0 3 3 2 1 AAA domain Torsin PF06309.6 CCD24795.1 - 0.0013 18.6 0.0 0.0057 16.5 0.0 2.1 1 0 0 1 1 1 1 Torsin IstB_IS21 PF01695.12 CCD24795.1 - 0.0014 18.0 0.0 0.19 11.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCD24795.1 - 0.0015 17.6 0.8 0.11 11.6 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.1 CCD24795.1 - 0.0027 17.5 0.0 0.34 10.7 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 CCD24795.1 - 0.0037 16.9 0.0 2.4 7.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain DUF815 PF05673.8 CCD24795.1 - 0.0048 15.8 0.3 0.17 10.8 0.0 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF815) NACHT PF05729.7 CCD24795.1 - 0.0067 16.0 0.0 5.2 6.7 0.0 2.8 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 CCD24795.1 - 0.012 15.9 3.2 1.6 9.0 0.0 3.7 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.1 CCD24795.1 - 0.013 14.9 0.1 2.7 7.5 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_3 PF07726.6 CCD24795.1 - 0.032 13.8 0.0 0.74 9.4 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CCD24795.1 - 0.04 14.0 0.1 6.6 6.9 0.0 3.0 3 0 0 3 3 2 0 RNA helicase MobB PF03205.9 CCD24795.1 - 0.046 13.4 0.0 7.6 6.2 0.0 3.0 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 CCD24795.1 - 0.054 13.0 0.0 12 5.3 0.0 2.7 2 1 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DUF258 PF03193.11 CCD24795.1 - 0.057 12.5 0.0 1.9 7.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 CCD24795.1 - 0.094 12.1 3.8 0.69 9.2 0.0 3.6 3 1 0 4 4 4 0 AAA-like domain Fe-S_biosyn PF01521.15 CCD24796.1 - 9.1e-18 64.2 0.0 7.5e-17 61.2 0.0 2.4 2 1 0 2 2 2 1 Iron-sulphur cluster biosynthesis DUF3853 PF12964.2 CCD24796.1 - 0.022 14.5 0.4 0.5 10.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3853) DUF2135 PF09906.4 CCD24796.1 - 0.11 12.4 1.5 0.29 11.1 1.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) SR-25 PF10500.4 CCD24796.1 - 1.1 8.6 28.9 6.9 6.0 20.0 2.1 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein MFS_1 PF07690.11 CCD24797.1 - 4e-39 134.3 31.8 4e-39 134.3 22.1 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCD24797.1 - 3.9e-09 35.2 5.1 7.1e-09 34.4 3.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCD24797.1 - 6.1e-09 34.9 27.4 6.1e-09 34.9 19.0 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter Peptidase_M24 PF00557.19 CCD24799.1 - 2.9e-36 124.9 0.0 4.2e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CCD24799.1 - 2.2e-09 37.8 0.0 2.3e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain KH_1 PF00013.24 CCD24800.1 - 0.0001 21.8 0.2 0.015 14.9 0.0 3.8 4 0 0 4 4 4 1 KH domain KH_3 PF13014.1 CCD24800.1 - 0.0062 16.1 0.3 2.3 7.9 0.0 3.9 3 0 0 3 3 3 1 KH domain AAA PF00004.24 CCD24802.1 - 1.5e-93 309.9 0.0 6.8e-47 158.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCD24802.1 - 4e-15 55.5 0.0 3.7e-08 32.7 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 CCD24802.1 - 4.9e-12 46.7 0.1 1.2e-06 29.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 CCD24802.1 - 3.6e-11 43.4 4.0 0.00025 21.0 0.0 4.0 4 2 0 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 CCD24802.1 - 6.2e-11 42.5 0.4 0.011 15.8 0.0 4.9 2 2 2 4 4 4 2 AAA domain AAA_2 PF07724.9 CCD24802.1 - 1.1e-10 41.7 0.0 0.0008 19.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 CCD24802.1 - 2.1e-10 40.6 0.0 0.00012 21.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CCD24802.1 - 2.4e-10 39.8 0.0 0.0008 18.5 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin AAA_14 PF13173.1 CCD24802.1 - 4.7e-10 39.4 0.0 0.0011 18.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CCD24802.1 - 1.7e-09 37.5 0.3 0.0018 18.0 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CCD24802.1 - 8e-09 34.6 0.1 0.00025 19.9 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 CCD24802.1 - 8.4e-08 32.5 3.7 0.00069 19.9 0.0 4.0 3 1 0 3 3 2 2 AAA domain RNA_helicase PF00910.17 CCD24802.1 - 2.7e-07 30.7 0.0 0.025 14.7 0.0 3.0 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.12 CCD24802.1 - 6.3e-07 28.9 0.2 0.023 14.1 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 CCD24802.1 - 6.3e-07 29.0 0.2 0.056 13.2 0.0 2.9 2 0 0 2 2 2 2 Part of AAA domain Vps4_C PF09336.5 CCD24802.1 - 1.2e-06 28.3 1.9 0.00024 20.9 0.1 3.6 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_28 PF13521.1 CCD24802.1 - 2e-06 27.8 0.0 0.04 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 CCD24802.1 - 3.7e-06 26.2 0.3 0.045 12.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCD24802.1 - 5.5e-06 26.0 0.0 0.039 13.5 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 CCD24802.1 - 5.8e-06 26.6 7.3 0.011 15.9 0.0 4.0 4 1 0 4 4 2 2 ABC transporter Cytidylate_kin2 PF13189.1 CCD24802.1 - 8.4e-06 25.8 0.0 0.0011 18.9 0.0 3.1 3 0 0 3 3 2 1 Cytidylate kinase-like family AAA_25 PF13481.1 CCD24802.1 - 8.7e-06 25.2 3.0 0.8 9.0 0.0 4.4 2 2 2 5 5 5 2 AAA domain NACHT PF05729.7 CCD24802.1 - 1.4e-05 24.7 0.1 0.45 10.1 0.0 3.6 4 0 0 4 4 4 2 NACHT domain SKI PF01202.17 CCD24802.1 - 1.7e-05 24.7 0.8 0.051 13.4 0.0 3.0 3 0 0 3 3 2 2 Shikimate kinase Sigma54_activ_2 PF14532.1 CCD24802.1 - 0.00021 21.3 0.0 0.7 9.9 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Viral_helicase1 PF01443.13 CCD24802.1 - 0.00021 20.8 0.3 0.94 8.9 0.0 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 CCD24802.1 - 0.00025 20.0 0.0 0.34 9.7 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain Sigma54_activat PF00158.21 CCD24802.1 - 0.0003 20.3 0.0 0.25 10.8 0.0 2.9 2 1 0 2 2 2 1 Sigma-54 interaction domain DUF815 PF05673.8 CCD24802.1 - 0.0003 19.7 0.0 0.14 11.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 CCD24802.1 - 0.00042 20.0 0.0 2.7 7.6 0.0 3.5 2 1 1 3 3 3 2 Archaeal ATPase CPT PF07931.7 CCD24802.1 - 0.0011 18.6 0.0 0.025 14.1 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 CCD24802.1 - 0.0013 17.9 0.0 1.5 7.9 0.0 3.2 2 1 1 3 3 3 1 KaiC ATP-synt_ab PF00006.20 CCD24802.1 - 0.0025 17.3 0.0 1.8 7.9 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Parvo_NS1 PF01057.12 CCD24802.1 - 0.0033 16.3 2.2 1.6 7.4 0.0 2.9 3 1 0 3 3 3 2 Parvovirus non-structural protein NS1 PhoH PF02562.11 CCD24802.1 - 0.0069 15.6 0.2 1.7 7.8 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein UPF0079 PF02367.12 CCD24802.1 - 0.012 15.2 0.0 5.3 6.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 CCD24802.1 - 0.015 14.9 0.0 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 CCD24802.1 - 0.021 14.3 0.0 7.2 6.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NifW PF03206.9 CCD24802.1 - 0.063 13.3 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 Nitrogen fixation protein NifW AAA_29 PF13555.1 CCD24802.1 - 0.11 12.0 0.0 6.6 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Clp1 PF06807.9 CCD24803.1 - 4.6e-05 23.2 0.0 0.0001 22.1 0.0 1.5 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MMR_HSR1 PF01926.18 CCD24803.1 - 0.00034 20.5 0.4 0.0019 18.1 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCD24803.1 - 0.00052 20.5 0.0 0.0038 17.7 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein FtsK_SpoIIIE PF01580.13 CCD24803.1 - 0.0019 17.7 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family MobB PF03205.9 CCD24803.1 - 0.002 17.8 0.1 0.0049 16.5 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CCD24803.1 - 0.0065 16.3 0.1 0.047 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CCD24803.1 - 0.011 15.9 0.1 0.08 13.2 0.0 2.2 2 0 0 2 2 2 0 ABC transporter Dynamin_N PF00350.18 CCD24803.1 - 0.067 13.0 2.3 0.44 10.3 0.6 2.7 2 1 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 CCD24803.1 - 0.07 13.4 0.1 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 CCD24803.1 - 0.081 13.7 0.0 0.3 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain WSC PF01822.14 CCD24804.1 - 6.6e-10 38.7 16.2 6.6e-10 38.7 11.2 3.3 3 0 0 3 3 3 1 WSC domain DUF912 PF06024.7 CCD24804.1 - 0.00028 20.8 0.9 0.00028 20.8 0.6 3.4 4 0 0 4 4 4 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1183 PF06682.7 CCD24804.1 - 0.0031 17.1 0.1 0.0031 17.1 0.1 4.0 3 1 0 3 3 3 1 Protein of unknown function (DUF1183) YajC PF02699.10 CCD24804.1 - 0.013 15.1 0.1 0.013 15.1 0.0 2.2 3 0 0 3 3 3 0 Preprotein translocase subunit Rifin_STEVOR PF02009.11 CCD24804.1 - 0.036 13.7 0.2 0.036 13.7 0.1 3.0 1 1 1 2 2 2 0 Rifin/stevor family Prp19 PF08606.6 CCD24805.1 - 6.6e-30 102.6 1.6 9.7e-30 102.1 1.1 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like U-box PF04564.10 CCD24805.1 - 0.00015 21.6 0.2 0.00043 20.1 0.1 1.8 1 1 0 1 1 1 1 U-box domain WEMBL PF05701.6 CCD24805.1 - 0.001 17.6 0.3 0.0012 17.3 0.2 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light zf-Nse PF11789.3 CCD24805.1 - 0.0053 16.2 0.5 0.058 12.9 0.0 2.4 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit HALZ PF02183.13 CCD24805.1 - 0.01 15.5 2.8 0.23 11.2 0.1 2.4 2 0 0 2 2 2 1 Homeobox associated leucine zipper BRE1 PF08647.6 CCD24805.1 - 0.052 13.5 6.0 0.2 11.6 4.1 1.9 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF972 PF06156.8 CCD24805.1 - 0.44 10.9 7.0 0.65 10.3 4.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 CCD24805.1 - 0.49 10.3 4.4 0.53 10.2 0.2 2.2 2 0 0 2 2 2 0 bZIP transcription factor ubiquitin PF00240.18 CCD24806.1 - 9.8e-103 335.6 15.6 6.5e-34 115.1 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 CCD24806.1 - 1.8e-59 197.3 13.8 2.5e-19 68.7 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCD24806.1 - 6.1e-19 68.0 6.5 9e-05 22.6 0.1 4.5 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCD24806.1 - 1e-16 61.0 0.5 0.00056 19.6 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCD24806.1 - 6.8e-11 42.0 1.2 0.078 12.8 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCD24806.1 - 1.2e-10 41.4 0.7 0.076 13.2 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CCD24806.1 - 5.4e-08 32.7 0.0 0.99 9.4 0.0 3.9 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 CCD24806.1 - 2e-05 24.3 2.6 2.8 7.9 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3221 PF11518.3 CCD24806.1 - 0.00019 21.0 0.4 8.7 6.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3221) FlgD_ig PF13860.1 CCD24806.1 - 0.00044 19.9 2.4 9.2 6.0 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 CCD24806.1 - 0.00083 17.7 8.1 1.5 7.0 0.2 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain Methyltrans_RNA PF04452.9 CCD24806.1 - 0.00085 18.5 0.1 1.2 8.2 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase Big_3_3 PF13750.1 CCD24806.1 - 0.011 15.2 0.0 30 3.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DUF3861 PF12977.2 CCD24806.1 - 0.015 15.3 2.7 31 4.7 0.0 3.4 1 1 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_4 PF13291.1 CCD24806.1 - 0.02 15.2 0.4 68 3.9 0.0 3.2 3 0 0 3 3 3 0 ACT domain GABP-alpha PF11620.3 CCD24806.1 - 0.034 14.1 3.9 26 4.8 0.1 3.1 3 0 0 3 3 3 0 GA-binding protein alpha chain Tash_PEST PF07708.6 CCD24806.1 - 0.036 13.9 19.8 2.5 8.1 1.2 3.4 3 0 0 3 3 3 0 Tash protein PEST motif CTDII PF01556.13 CCD24806.1 - 0.052 13.4 9.2 5 7.0 0.2 3.4 1 1 2 3 3 3 0 DnaJ C terminal domain EMG1 PF03587.9 CCD24806.1 - 0.059 12.6 0.9 16 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase FERM_N PF09379.5 CCD24806.1 - 0.092 12.8 8.6 28 4.8 0.2 4.7 3 3 0 3 3 3 0 FERM N-terminal domain DUF3781 PF12636.2 CCD24806.1 - 0.29 11.1 3.6 70 3.4 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) CDC48_2 PF02933.12 CCD24806.1 - 3.3 7.4 7.5 46 3.7 0.1 3.1 3 0 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 KID PF02524.9 CCD24806.1 - 6.8 7.2 8.1 2.1e+02 2.8 0.1 4.8 3 0 0 3 3 3 0 KID repeat DUF1162 PF06650.7 CCD24807.1 - 4e-81 272.2 9.9 2.8e-76 256.3 0.3 3.5 3 0 0 3 3 3 3 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CCD24807.1 - 1.4e-37 127.7 0.2 5e-37 126.0 0.1 2.1 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Fer2_3 PF13085.1 CCD24808.1 - 4.2e-32 110.2 0.1 6.5e-32 109.6 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CCD24808.1 - 5.6e-09 36.2 5.3 5.6e-09 36.2 3.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CCD24808.1 - 1.3e-07 31.5 3.9 1.3e-07 31.5 2.7 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CCD24808.1 - 2.8e-05 24.4 0.6 2.8e-05 24.4 0.4 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CCD24808.1 - 0.00021 21.6 1.9 0.00021 21.6 1.3 2.6 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 CCD24808.1 - 0.0012 18.6 4.5 0.0012 18.6 3.1 2.7 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CCD24808.1 - 0.0042 16.8 1.4 0.0042 16.8 1.0 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.1 CCD24808.1 - 0.26 11.5 12.9 23 5.3 0.0 3.1 2 1 0 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.1 CCD24808.1 - 0.45 11.1 0.2 0.45 11.1 0.1 2.8 4 0 0 4 4 4 0 4Fe-4S single cluster domain Autophagy_act_C PF03987.10 CCD24809.1 - 4e-08 33.3 1.4 1.8e-07 31.2 1.0 2.1 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain MIP PF00230.15 CCD24810.1 - 1.1e-74 250.7 8.6 1.6e-74 250.2 5.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Ribosomal_L7Ae PF01248.21 CCD24811.1 - 6.6e-23 80.0 0.2 1.1e-22 79.3 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CCD24811.1 - 0.00021 21.1 0.1 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 DUF1409 PF07197.7 CCD24812.1 - 0.043 13.8 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) FAM198 PF15051.1 CCD24812.1 - 0.06 12.0 0.1 0.1 11.2 0.1 1.3 1 0 0 1 1 1 0 FAM198 protein CreA PF05981.7 CCD24812.1 - 0.095 12.2 0.0 0.4 10.2 0.0 1.8 1 1 1 2 2 2 0 CreA protein IBD PF10416.4 CCD24812.1 - 0.24 11.1 1.8 0.28 10.9 0.2 1.8 2 0 0 2 2 2 0 Transcription-initiator DNA-binding domain IBD HSBP1 PF06825.7 CCD24812.1 - 1.7 8.3 7.7 10 5.8 1.1 3.1 2 1 0 2 2 2 0 Heat shock factor binding protein 1 Ferric_reduct PF01794.14 CCD24813.1 - 2.4e-22 79.3 16.2 3.8e-22 78.7 7.7 2.9 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CCD24813.1 - 8.9e-20 71.1 0.0 1.8e-19 70.1 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CCD24813.1 - 2.7e-19 68.9 0.0 4.7e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain MLANA PF14991.1 CCD24813.1 - 0.42 10.6 6.3 17 5.4 0.2 3.3 2 1 1 3 3 3 0 Protein melan-A DUF4293 PF14126.1 CCD24813.1 - 1.5 8.7 11.3 0.037 13.9 1.7 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4293) Sugar_tr PF00083.19 CCD24814.1 - 3.3e-161 536.8 36.3 3.7e-161 536.6 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD24814.1 - 1.3e-28 99.7 38.6 2.3e-26 92.3 18.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCD24814.1 - 0.00017 19.8 1.5 0.00017 19.8 1.0 2.1 3 0 0 3 3 3 1 Transmembrane secretion effector MFS_2 PF13347.1 CCD24814.1 - 0.0039 15.6 3.8 0.0039 15.6 2.6 3.2 1 1 2 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 CCD24815.1 - 2.5e-162 540.5 35.8 2.9e-162 540.3 24.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD24815.1 - 2.2e-29 102.2 38.1 6.2e-27 94.2 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCD24815.1 - 0.00014 20.1 1.3 0.00014 20.1 0.9 2.1 3 0 0 3 3 3 1 Transmembrane secretion effector MFS_2 PF13347.1 CCD24815.1 - 0.0037 15.7 33.8 0.014 13.8 2.2 3.4 1 1 2 3 3 3 2 MFS/sugar transport protein PRP21_like_P PF12230.3 CCD24817.1 - 1.3e-37 129.4 7.8 4.5e-36 124.4 5.4 2.1 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Sugar_tr PF00083.19 CCD24818.1 - 2.8e-64 217.3 27.4 3.2e-64 217.1 19.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD24818.1 - 0.0024 16.6 21.5 0.0072 15.0 14.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF373 PF04123.8 CCD24818.1 - 6.2 5.7 6.4 1.4 7.8 1.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF373) GSHPx PF00255.14 CCD24819.1 - 3.2e-44 148.7 0.2 4.1e-44 148.3 0.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CCD24819.1 - 7.4e-06 25.6 0.1 1.8e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCD24819.1 - 0.00012 21.6 0.1 0.00018 21.0 0.1 1.6 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 CCD24819.1 - 0.0041 17.2 0.0 0.0076 16.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Sir1 PF11603.3 CCD24820.1 - 1.4e-14 54.3 4.1 1.6e-07 31.5 0.0 3.6 3 0 0 3 3 3 3 Regulatory protein Sir1 ADH_zinc_N PF00107.21 CCD24821.1 - 1.2e-17 63.6 0.0 2.3e-17 62.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCD24821.1 - 0.00085 20.2 0.0 0.0024 18.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DUF2855 PF11017.3 CCD24821.1 - 0.0044 16.2 0.0 0.0073 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) LAB_N PF07578.6 CCD24821.1 - 0.054 13.4 0.3 0.13 12.1 0.2 1.7 1 1 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain Epimerase PF01370.16 CCD24822.1 - 4.1e-18 65.6 0.0 5.7e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCD24822.1 - 3.1e-14 52.3 0.0 4.3e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCD24822.1 - 2.8e-09 37.2 0.0 4.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCD24822.1 - 6.8e-07 28.4 0.0 1.5e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein DapB_N PF01113.15 CCD24822.1 - 0.00045 20.1 0.0 0.00089 19.1 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus OMS28_porin PF03532.8 CCD24822.1 - 0.00095 18.3 0.0 0.0018 17.3 0.0 1.5 1 0 0 1 1 1 1 OMS28 porin NmrA PF05368.8 CCD24822.1 - 0.0016 17.7 0.0 0.038 13.2 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 CCD24822.1 - 0.015 15.1 0.0 0.053 13.4 0.0 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCD24822.1 - 0.016 14.1 0.1 0.025 13.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 CCD24822.1 - 0.033 14.6 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 CCD24822.1 - 0.071 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 CCD24823.1 - 0.0012 17.5 0.1 0.0012 17.5 0.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1328 PF07043.8 CCD24823.1 - 0.018 15.0 0.2 0.065 13.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1328) ECF-ribofla_trS PF07155.7 CCD24823.1 - 0.037 13.7 2.2 0.042 13.5 1.5 1.0 1 0 0 1 1 1 0 ECF-type riboflavin transporter, S component DEAD PF00270.24 CCD24825.1 - 1.6e-10 40.7 0.0 4.1e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCD24825.1 - 0.17 12.0 0.0 0.5 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sir1 PF11603.3 CCD24826.1 - 2.5e-09 37.3 0.1 3.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Regulatory protein Sir1 Reg_prop PF07494.6 CCD24826.1 - 0.04 13.9 0.1 0.19 11.8 0.1 2.1 2 0 0 2 2 2 0 Two component regulator propeller Toxin_54 PF15533.1 CCD24826.1 - 0.067 13.4 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Putative toxin 54 EABR PF12180.3 CCD24826.1 - 0.093 12.0 0.8 0.21 10.9 0.5 1.5 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Ribonuclease_3 PF00636.21 CCD24828.1 - 2.7e-22 79.3 1.1 2.1e-21 76.4 0.0 3.0 3 0 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCD24828.1 - 3.8e-17 62.4 0.0 8.4e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 CCD24828.1 - 2.1e-14 53.8 0.1 6.4e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif GFO_IDH_MocA PF01408.17 CCD24829.1 - 2e-21 76.7 0.1 1.1e-20 74.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCD24829.1 - 1.7e-07 31.0 0.0 3.1e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain TFIID-18kDa PF02269.11 CCD24830.1 - 2.7e-32 110.4 0.0 4.6e-32 109.6 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 CCD24830.1 - 0.0022 18.0 0.0 0.0061 16.6 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PBP1_TM PF14812.1 CCD24830.1 - 2.3 8.5 10.0 1.6 9.0 5.6 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ERO1 PF04137.10 CCD24831.1 - 1.4e-116 389.4 8.2 1.4e-116 389.4 5.7 2.3 2 0 0 2 2 2 2 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Proteasome PF00227.21 CCD24832.1 - 7.2e-58 194.9 0.0 9.2e-58 194.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCD24832.1 - 3.8e-09 35.6 0.8 7e-09 34.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature COX14 PF14880.1 CCD24833.1 - 2.5e-22 78.2 2.0 2.9e-22 78.0 1.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase c assembly Ish1 PF10281.4 CCD24834.1 - 1.9e-39 133.3 34.8 5.2e-09 36.0 2.4 7.0 6 0 0 6 6 6 6 Putative stress-responsive nuclear envelope protein Mst1_SARAH PF11629.3 CCD24834.1 - 0.042 13.6 1.7 14 5.5 0.0 4.3 4 0 0 4 4 4 0 C terminal SARAH domain of Mst1 SAM_2 PF07647.12 CCD24834.1 - 0.12 12.1 9.4 5.6 6.8 0.1 4.8 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) HeH PF12949.2 CCD24834.1 - 0.17 11.4 4.7 22 4.6 0.0 4.4 4 0 0 4 4 4 0 HeH/LEM domain SAM_1 PF00536.25 CCD24834.1 - 0.62 10.2 6.5 10 6.3 0.1 4.1 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) SAP30_Sin3_bdg PF13867.1 CCD24834.1 - 1.3 8.9 4.2 54 3.7 0.0 3.5 3 0 0 3 3 3 0 Sin3 binding region of histone deacetylase complex subunit SAP30 FAD_binding_6 PF00970.19 CCD24836.1 - 9.1e-26 89.8 0.0 1.8e-25 88.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CCD24836.1 - 9.8e-25 87.2 0.0 1.5e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CCD24836.1 - 1.4e-05 25.0 0.0 0.00017 21.4 0.0 2.1 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF4131 PF13567.1 CCD24836.1 - 0.14 11.5 0.3 0.31 10.4 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Sugar_tr PF00083.19 CCD24837.1 - 9.6e-41 139.7 20.4 1.8e-39 135.6 14.2 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD24837.1 - 3.5e-23 81.9 14.9 7.4e-15 54.5 7.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BRI3BP PF14965.1 CCD24837.1 - 0.057 12.7 0.5 0.15 11.4 0.4 1.6 1 0 0 1 1 1 0 Negative regulator of p53/TP53 Gtr1_RagA PF04670.7 CCD24838.1 - 6e-94 313.5 4.9 7.4e-94 313.2 3.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CCD24838.1 - 1.4e-09 37.5 0.7 3.6e-09 36.2 0.1 1.9 2 0 0 2 2 2 1 Ras family Arf PF00025.16 CCD24838.1 - 1.1e-07 31.2 0.2 1.8e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CCD24838.1 - 1.3e-07 32.0 0.1 3.5e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCD24838.1 - 5.4e-06 26.3 0.1 1.6e-05 24.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CCD24838.1 - 0.0042 16.5 0.1 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3939 PF13075.1 CCD24838.1 - 0.05 13.3 0.4 0.11 12.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3939) Guanylate_kin PF00625.16 CCD24838.1 - 1.8 7.9 6.0 0.86 9.0 0.8 2.5 2 1 0 2 2 2 0 Guanylate kinase ABC_tran PF00005.22 CCD24838.1 - 2.6 8.3 8.8 6.9 6.9 6.1 2.1 1 1 0 1 1 1 0 ABC transporter Pyr_redox_2 PF07992.9 CCD24839.1 - 5.6e-28 98.2 2.2 7.9e-18 65.0 0.0 3.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCD24839.1 - 2.3e-13 50.3 0.1 1.1e-11 44.9 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCD24839.1 - 2.3e-09 37.6 0.7 8.4e-05 22.7 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCD24839.1 - 0.029 13.2 0.1 1 8.2 0.1 2.8 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 CCD24839.1 - 0.15 11.8 0.8 11 5.8 0.1 3.4 2 2 1 3 3 3 0 FAD-NAD(P)-binding Ribosomal_L30 PF00327.15 CCD24841.1 - 2.8e-12 46.0 0.6 4.6e-12 45.3 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Exo_endo_phos PF03372.18 CCD24842.1 - 1.6e-18 67.5 0.0 2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SpoIIIAH PF12685.2 CCD24842.1 - 6.2 6.2 11.6 14 5.1 0.3 2.2 2 0 0 2 2 2 0 SpoIIIAH-like protein Nab6_mRNP_bdg PF10567.4 CCD24843.1 - 7.4e-73 245.2 36.9 5.9e-59 199.5 13.8 3.5 3 0 0 3 3 3 2 RNA-recognition motif RRM PF10378.4 CCD24843.1 - 2.3e-16 59.1 9.0 2.3e-16 59.1 6.2 2.9 2 0 0 2 2 2 1 Putative RRM domain RRM_6 PF14259.1 CCD24843.1 - 1.6e-09 37.6 0.3 7.8e-06 25.7 0.0 4.0 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD24843.1 - 8.7e-07 28.6 0.5 0.0039 17.0 0.0 3.6 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCD24843.1 - 5.1e-06 26.0 0.1 0.0057 16.2 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 CCD24844.1 - 5.1e-35 120.8 56.2 3.1e-33 114.9 38.9 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCD24844.1 - 5.3e-05 21.9 10.1 5.3e-05 21.9 7.0 3.5 1 1 2 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 CCD24844.1 - 0.27 9.6 46.5 0.17 10.2 0.9 3.5 1 1 0 2 2 2 0 MFS/sugar transport protein Anp1 PF03452.9 CCD24845.1 - 5.4e-124 412.6 0.0 7.7e-124 412.1 0.0 1.2 1 0 0 1 1 1 1 Anp1 DUF2232 PF09991.4 CCD24845.1 - 0.047 12.6 0.0 0.07 12.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) BcsB PF03170.8 CCD24845.1 - 0.13 10.2 0.0 0.19 9.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit TAF8_C PF10406.4 CCD24846.1 - 6.5e-21 74.1 0.1 6.5e-21 74.1 0.1 3.0 2 1 1 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term CTK3_C PF12350.3 CCD24848.1 - 2e-13 50.1 10.9 1.3e-12 47.5 7.6 2.3 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.3 CCD24848.1 - 1.9e-06 27.5 6.8 0.011 15.3 0.0 3.1 3 0 0 3 3 3 2 CTD kinase subunit gamma CTK3 Bul1_N PF04425.7 CCD24849.1 - 8.8e-164 545.2 15.2 8.8e-164 545.2 10.5 3.1 3 0 0 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 CCD24849.1 - 3.3e-82 275.7 12.5 7.6e-58 195.8 3.1 5.0 4 1 1 5 5 5 2 Bul1 C terminus Ubie_methyltran PF01209.13 CCD24850.1 - 2.8e-97 324.4 0.1 3.4e-97 324.1 0.1 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CCD24850.1 - 9.2e-12 44.8 0.0 1.3e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCD24850.1 - 4.2e-09 36.7 0.0 7.9e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD24850.1 - 2.3e-08 34.3 0.0 4.1e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCD24850.1 - 4.3e-08 33.5 0.0 7.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCD24850.1 - 1.4e-07 31.3 0.0 2.4e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD24850.1 - 1.6e-05 25.4 0.0 3e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CCD24850.1 - 0.012 15.2 0.0 0.21 11.2 0.0 2.4 2 1 0 3 3 3 0 Hypothetical methyltransferase Methyltransf_26 PF13659.1 CCD24850.1 - 0.025 14.6 0.0 0.11 12.4 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 CCD24850.1 - 0.041 13.5 0.0 0.065 12.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Zds_C PF08632.5 CCD24851.1 - 9.4e-33 111.3 1.4 1.8e-32 110.4 1.0 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF1892 PF08987.5 CCD24852.1 - 2.8e-38 130.4 9.1 1.3e-36 125.1 6.3 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1892) SpoU_methylase PF00588.14 CCD24852.1 - 0.02 14.7 0.0 0.026 14.4 0.0 1.1 1 0 0 1 1 1 0 SpoU rRNA Methylase family Pribosyltran PF00156.22 CCD24853.1 - 1.1e-17 63.8 0.2 4.6e-17 61.8 0.1 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain DUF3186 PF11382.3 CCD24853.1 - 0.02 14.0 0.1 0.028 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) SRP19 PF01922.12 CCD24854.1 - 4.7e-29 100.8 0.0 9.4e-29 99.8 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein PXA PF02194.10 CCD24855.1 - 1.8e-39 135.2 1.8 1.8e-39 135.2 1.3 3.0 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 CCD24855.1 - 7.4e-25 87.2 0.1 4e-24 84.8 0.0 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 CCD24855.1 - 2e-11 43.6 3.6 2e-11 43.6 2.5 2.8 2 0 0 2 2 2 1 PX domain Nup188 PF10487.4 CCD24856.1 - 3.3e-161 538.3 83.5 3.3e-161 538.3 57.9 2.2 1 1 1 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 WD40 PF00400.27 CCD24857.1 - 5.4e-30 102.1 7.5 3.3e-07 29.9 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CCD24857.1 - 0.00014 21.6 2.6 0.18 11.4 0.2 3.9 3 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A CUE PF02845.11 CCD24858.1 - 8.6e-11 41.1 0.0 1.5e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 CUE domain TFIIA PF03153.8 CCD24858.1 - 0.0032 17.4 20.0 0.0041 17.0 13.9 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Glyco_transf_20 PF00982.16 CCD24859.1 - 8.3e-165 548.8 1.7 8.3e-165 548.8 1.2 1.8 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCD24859.1 - 1.2e-42 145.4 0.1 3.2e-42 144.0 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase zf-C3HC4 PF00097.20 CCD24860.1 - 1.2e-09 37.6 7.5 1.2e-09 37.6 5.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCD24860.1 - 3.2e-09 36.3 13.4 1.5e-08 34.1 3.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCD24860.1 - 5e-09 35.8 9.1 5e-09 35.8 6.3 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 CCD24860.1 - 3.5e-08 33.3 8.8 3.5e-08 33.3 6.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCD24860.1 - 6.8e-08 32.2 7.7 6.8e-08 32.2 5.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CCD24860.1 - 2.5e-07 30.2 2.7 6.3e-07 29.0 1.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CCD24860.1 - 5.1e-07 29.3 7.5 5.1e-07 29.3 5.2 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 CCD24860.1 - 0.0043 17.1 3.5 0.0043 17.1 2.4 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger zf-ribbon_3 PF13248.1 CCD24860.1 - 0.005 15.9 1.0 0.005 15.9 0.7 3.0 2 1 0 2 2 1 1 zinc-ribbon domain zf-Apc11 PF12861.2 CCD24860.1 - 0.0083 15.9 2.4 0.0083 15.9 1.7 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CCD24860.1 - 0.0099 15.4 14.6 0.059 12.9 4.6 2.9 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain DZR PF12773.2 CCD24860.1 - 0.015 15.1 10.6 0.28 11.0 0.3 2.6 2 0 0 2 2 2 0 Double zinc ribbon HMA PF00403.21 CCD24860.1 - 0.017 15.2 0.1 0.52 10.4 0.0 2.6 2 0 0 2 2 2 0 Heavy-metal-associated domain zf-RING_6 PF14835.1 CCD24860.1 - 0.023 14.5 2.6 0.023 14.5 1.8 1.9 2 0 0 2 2 2 0 zf-RING of BARD1-type protein DUF164 PF02591.10 CCD24860.1 - 0.035 13.9 4.0 0.15 11.8 0.0 3.3 3 1 1 4 4 3 0 Putative zinc ribbon domain HypA PF01155.14 CCD24860.1 - 0.12 12.1 5.2 0.81 9.3 0.1 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family CDC45 PF02724.9 CCD24860.1 - 1.2 7.1 55.2 0.65 7.9 11.6 2.2 1 1 1 2 2 2 0 CDC45-like protein zf-MIZ PF02891.15 CCD24860.1 - 2.5 7.6 10.0 1.1 8.7 4.2 2.2 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-RING_3 PF14369.1 CCD24860.1 - 3.5 7.6 18.5 1.3 9.0 1.0 3.5 3 1 1 4 4 3 0 zinc-finger Cytochrome_C7 PF14522.1 CCD24860.1 - 8.3 6.1 8.5 15 5.3 0.2 2.8 2 1 0 2 2 2 0 Cytochrome c7 ETRAMP PF09716.5 CCD24861.1 - 0.083 12.8 0.1 0.083 12.8 0.1 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) RRM_1 PF00076.17 CCD24863.1 - 6.8e-23 80.0 1.2 3.4e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD24863.1 - 1e-15 57.4 0.1 7.8e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD24863.1 - 6.6e-08 32.2 0.5 3.5e-05 23.5 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VPS9 PF02204.13 CCD24863.1 - 0.0063 16.5 1.5 0.015 15.2 1.0 1.6 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain MMS19_C PF12460.3 CCD24863.1 - 0.37 9.4 4.8 0.65 8.6 3.4 1.4 1 1 0 1 1 1 0 RNAPII transcription regulator C-terminal AMP-binding PF00501.23 CCD24864.1 - 4.9e-78 262.3 0.0 6.5e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCD24864.1 - 0.015 16.2 0.0 0.039 14.9 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain PagP PF07017.6 CCD24864.1 - 0.028 13.7 0.1 0.074 12.3 0.0 1.7 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP Bac_rhodopsin PF01036.13 CCD24865.1 - 9.9e-59 198.3 16.6 1.1e-58 198.1 11.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 CCD24865.1 - 0.045 13.1 12.1 0.67 9.3 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2633 PF11119.3 CCD24865.1 - 1.3 8.8 3.3 0.98 9.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) Cation_efflux PF01545.16 CCD24866.1 - 5.2e-80 268.5 0.1 9e-80 267.7 0.1 1.3 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.17 CCD24866.1 - 2.2e-06 26.9 2.0 4.7e-06 25.8 1.4 1.5 1 0 0 1 1 1 1 ZIP Zinc transporter TcpE PF12648.2 CCD24866.1 - 0.11 12.6 2.2 1.4 9.0 0.1 2.7 1 1 1 2 2 2 0 TcpE family DUF2746 PF10874.3 CCD24868.1 - 0.13 12.5 0.6 7.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Ribosomal_L18ae PF01775.12 CCD24869.1 - 2.8e-57 191.9 1.5 3.9e-57 191.5 1.0 1.2 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain GET2 PF08690.5 CCD24869.1 - 0.064 12.4 0.0 0.09 12.0 0.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 DUF1057 PF06342.7 CCD24869.1 - 0.082 11.7 0.3 0.16 10.7 0.1 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) CTP_transf_1 PF01148.15 CCD24870.1 - 3.7e-20 72.6 13.3 5.6e-18 65.5 4.3 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family DUF606 PF04657.8 CCD24870.1 - 0.044 13.8 1.2 0.08 13.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF606 Nop PF01798.13 CCD24871.1 - 3.1e-59 198.5 0.9 2e-58 195.9 0.7 2.2 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 CCD24871.1 - 4.2e-27 93.7 0.3 1e-26 92.4 0.0 1.9 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CCD24871.1 - 3.4e-18 65.5 1.7 3.4e-18 65.5 1.2 3.1 2 1 1 3 3 3 1 NOP5NT (NUC127) domain SART-1 PF03343.8 CCD24872.1 - 2e-62 211.4 55.3 5.4e-62 210.0 38.3 1.6 1 1 0 1 1 1 1 SART-1 family rOmpB PF12334.3 CCD24872.1 - 0.026 13.8 0.0 0.054 12.8 0.0 1.5 1 0 0 1 1 1 0 Rickettsia outer membrane protein B TPT PF03151.11 CCD24873.1 - 3.3e-20 72.2 8.3 3.3e-20 72.2 5.8 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CCD24873.1 - 0.00042 20.3 9.7 0.00042 20.3 6.7 4.0 3 1 1 4 4 4 1 EamA-like transporter family PIRT PF15099.1 CCD24873.1 - 0.11 11.7 2.3 2 7.6 0.0 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family MFS_1 PF07690.11 CCD24874.1 - 6.9e-25 87.5 28.4 1.6e-24 86.2 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCD24874.1 - 1.1e-09 37.3 28.2 7.7e-08 31.3 2.1 3.5 1 1 1 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.2 CCD24874.1 - 0.18 11.6 0.1 0.18 11.6 0.0 2.9 3 1 0 3 3 3 0 MFS_1 like family FLO_LFY PF01698.11 CCD24874.1 - 6.5 5.4 5.9 9.4 4.9 4.1 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2034 PF10356.4 CCD24875.1 - 4.3e-55 185.7 0.0 5.2e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 CCD24875.1 - 3.5e-05 23.5 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 2 Restriction endonuclease MRP-S26 PF14943.1 CCD24876.1 - 0.013 15.0 2.0 0.013 15.0 1.4 1.5 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 DUF1940 PF09155.5 CCD24876.1 - 0.044 13.6 2.0 0.055 13.3 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1940) ScpA_ScpB PF02616.9 CCD24876.1 - 0.064 12.8 3.8 0.068 12.7 2.6 1.1 1 0 0 1 1 1 0 ScpA/B protein Baculo_PEP_C PF04513.7 CCD24876.1 - 0.12 12.1 0.2 0.16 11.8 0.1 1.2 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TBCA PF02970.11 CCD24876.1 - 0.2 11.7 5.3 0.23 11.5 3.7 1.1 1 0 0 1 1 1 0 Tubulin binding cofactor A Erp_C PF06780.6 CCD24876.1 - 0.28 11.0 7.8 0.4 10.5 5.4 1.3 1 1 0 1 1 1 0 Erp protein C-terminus Streptin-Immun PF11083.3 CCD24876.1 - 0.35 10.9 5.6 4.7 7.2 0.2 2.1 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein Frigida PF07899.6 CCD24876.1 - 0.4 9.3 3.1 0.45 9.2 2.1 1.1 1 0 0 1 1 1 0 Frigida-like protein V-SNARE PF05008.10 CCD24876.1 - 0.83 9.8 4.2 0.78 9.9 0.7 2.0 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF2205 PF10224.4 CCD24876.1 - 1.1 8.8 4.8 1.5 8.4 3.3 1.3 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Syntaxin PF00804.20 CCD24876.1 - 1.2 9.3 6.2 1.6 8.9 4.3 1.3 1 1 0 1 1 1 0 Syntaxin DUF1664 PF07889.7 CCD24876.1 - 1.4 8.7 4.0 1.7 8.4 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) SNF2_N PF00176.18 CCD24877.1 - 1.8e-82 276.5 0.9 4.3e-82 275.2 0.6 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CCD24877.1 - 1.6e-43 147.1 5.3 1.6e-43 147.1 3.7 4.1 4 1 1 5 5 5 1 SLIDE HAND PF09110.6 CCD24877.1 - 1.4e-31 109.1 19.5 1.4e-31 109.1 13.5 5.8 6 1 0 6 6 6 1 HAND Helicase_C PF00271.26 CCD24877.1 - 2.2e-16 59.4 0.0 1.9e-15 56.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD24877.1 - 8.7e-07 28.5 0.0 2.2e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCD24877.1 - 0.041 14.0 2.2 0.18 11.9 0.1 3.2 3 1 0 3 3 3 0 AAA domain GATase PF00117.23 CCD24878.1 - 1.7e-47 161.3 0.0 2.4e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 CCD24878.1 - 3.9e-45 152.5 0.0 6e-45 151.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 CCD24878.1 - 1.9e-06 27.5 0.1 0.00019 20.9 0.0 2.8 1 1 1 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.19 CCD24878.1 - 0.0065 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family RGS PF00615.14 CCD24879.1 - 0.00011 22.3 2.1 0.00041 20.4 0.2 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF4414 PF14377.1 CCD24879.1 - 1.3 8.9 5.8 1.1 9.1 0.0 2.9 2 1 2 4 4 4 0 Domain of unknown function (DUF4414) ChAPs PF09295.5 CCD24880.1 - 4e-159 529.6 2.0 5.6e-159 529.1 1.4 1.2 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 CCD24880.1 - 3.4e-05 23.4 1.1 0.084 12.5 0.3 2.6 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.1 CCD24880.1 - 0.0038 17.7 0.1 16 6.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCD24880.1 - 0.0043 16.7 0.0 6.3 6.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCD24880.1 - 0.0091 16.3 0.0 7.5 7.2 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCD24880.1 - 0.0098 16.5 0.2 11 6.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCD24880.1 - 0.042 14.1 0.1 0.74 10.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCD24880.1 - 0.042 13.7 4.0 0.15 12.0 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCD24880.1 - 0.05 13.2 0.1 1.3 8.7 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCD24880.1 - 0.1 12.8 0.7 0.35 11.1 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Acyltransferase PF01553.16 CCD24881.1 - 0.017 14.5 0.0 0.051 13.0 0.0 1.8 1 1 0 1 1 1 0 Acyltransferase CybS PF05328.7 CCD24882.1 - 1.8e-38 131.1 0.0 2.4e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 CybS RNase_H PF00075.19 CCD24883.1 - 5.6e-27 94.6 0.0 1.2e-26 93.6 0.0 1.6 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 CCD24883.1 - 4.4e-24 84.2 5.2 1.2e-13 50.7 1.8 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin Membr_traf_MHD PF10540.4 CCD24884.1 - 2.8e-15 56.3 0.0 1.2e-14 54.3 0.0 2.1 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 CCD24884.1 - 1.4e-11 44.1 0.0 3.3e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain SWIB PF02201.13 CCD24885.1 - 4.3e-17 61.5 0.6 4.2e-16 58.3 0.0 2.3 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 CCD24885.1 - 8.4e-05 22.2 0.1 0.001 18.8 0.1 2.4 2 0 0 2 2 2 1 DEK C terminal domain GRA6 PF05084.8 CCD24885.1 - 0.2 11.1 3.1 0.35 10.3 2.2 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) ATP11 PF06644.6 CCD24885.1 - 6 6.2 14.1 0.81 9.1 4.4 2.2 2 0 0 2 2 2 0 ATP11 protein RRS1 PF04939.7 CCD24886.1 - 4.3e-63 211.6 5.7 4.9e-63 211.4 3.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) S10_plectin PF03501.10 CCD24887.1 - 2.2e-42 142.8 0.6 2.6e-42 142.6 0.4 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF505 PF04458.7 CCD24887.1 - 0.0076 14.4 0.3 0.009 14.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF505) HTH_45 PF14947.1 CCD24887.1 - 0.021 14.6 0.2 0.038 13.7 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix tRNA-synt_1c_C PF03950.13 CCD24887.1 - 0.041 13.5 0.1 0.045 13.4 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain PadR PF03551.9 CCD24887.1 - 0.042 13.6 1.3 0.055 13.2 0.1 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family Replic_Relax PF13814.1 CCD24887.1 - 0.077 12.8 0.1 0.09 12.6 0.1 1.2 1 0 0 1 1 1 0 Replication-relaxation YjcQ PF09639.5 CCD24887.1 - 0.084 12.9 0.2 0.13 12.3 0.1 1.3 1 0 0 1 1 1 0 YjcQ protein DUF3116 PF11313.3 CCD24887.1 - 0.15 11.6 1.4 0.22 11.1 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3116) Mpv17_PMP22 PF04117.7 CCD24888.1 - 1.4e-19 69.4 1.6 1.4e-19 69.4 1.1 3.0 3 0 0 3 3 3 1 Mpv17 / PMP22 family P5-ATPase PF12409.3 CCD24889.1 - 2.2e-36 124.3 0.0 8.4e-36 122.4 0.0 2.1 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 CCD24889.1 - 1e-29 103.2 0.0 1.9e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CCD24889.1 - 4e-25 89.1 0.0 9.3e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCD24889.1 - 2.3e-18 67.3 0.0 9.6e-15 55.5 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCD24889.1 - 3.1e-05 23.8 0.0 7.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCD24889.1 - 0.00024 20.7 0.2 0.61 9.6 0.0 3.9 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase Thioredoxin PF00085.15 CCD24891.1 - 2.1e-24 85.2 1.4 8.7e-24 83.1 0.8 2.2 2 1 0 3 3 3 1 Thioredoxin Thioredoxin_2 PF13098.1 CCD24891.1 - 1.4e-06 28.4 1.6 5.3e-06 26.6 1.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCD24891.1 - 5.5e-06 26.4 1.6 6.2e-05 23.0 1.1 2.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_6 PF13848.1 CCD24891.1 - 0.00039 20.2 0.0 0.062 13.0 0.0 3.1 2 1 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CCD24891.1 - 0.00079 19.4 0.1 0.0018 18.2 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 CCD24891.1 - 0.0066 16.2 0.5 0.016 15.0 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin domain TraF PF13728.1 CCD24891.1 - 0.014 14.9 0.1 0.014 14.9 0.0 2.0 1 1 1 2 2 2 0 F plasmid transfer operon protein Thioredoxin_9 PF14595.1 CCD24891.1 - 0.015 14.8 0.0 0.015 14.8 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin AhpC-TSA PF00578.16 CCD24891.1 - 0.017 14.7 0.1 0.039 13.6 0.1 1.6 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.5 CCD24891.1 - 0.03 13.8 0.4 0.061 12.8 0.3 1.5 1 0 0 1 1 1 0 Redoxin Menin PF05053.8 CCD24891.1 - 0.32 9.1 4.0 0.43 8.7 2.8 1.1 1 0 0 1 1 1 0 Menin DUF912 PF06024.7 CCD24891.1 - 0.51 10.4 6.3 1.2 9.2 4.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF947 PF06102.7 CCD24892.1 - 5e-41 140.3 27.5 5e-41 140.3 19.0 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF947) Inositol_P PF00459.20 CCD24892.1 - 2.6 7.2 5.8 4.3 6.5 4.0 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family Rhodanese PF00581.15 CCD24893.1 - 8.5e-13 48.6 0.0 1.3e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.15 CCD24894.1 - 6.4e-18 65.1 0.0 8.2e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain His_Phos_1 PF00300.17 CCD24895.1 - 9.7e-30 103.7 0.0 1.2e-29 103.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Shikimate_DH PF01488.15 CCD24895.1 - 0.057 13.5 0.1 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Phosducin PF02114.11 CCD24896.1 - 4.4e-07 28.8 4.7 3.5e-06 25.9 3.3 2.0 1 1 0 1 1 1 1 Phosducin UCH PF00443.24 CCD24897.1 - 2e-56 191.1 15.3 3.2e-56 190.4 10.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCD24897.1 - 2.3e-25 89.6 16.9 2.3e-25 89.6 11.7 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCD24897.1 - 4e-10 39.6 5.4 4e-10 39.6 3.8 4.3 4 1 1 5 5 5 1 Zn-finger in ubiquitin-hydrolases and other protein C1_3 PF07649.7 CCD24897.1 - 0.021 14.8 4.2 0.021 14.8 2.9 4.3 5 0 0 5 5 5 0 C1-like domain FSH1 PF03959.8 CCD24898.1 - 9.5e-66 221.2 0.0 1.3e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CCD24898.1 - 6.3e-08 32.4 0.0 9.2e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCD24898.1 - 0.00092 18.7 0.0 0.0025 17.2 0.0 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 CCD24898.1 - 0.0081 16.0 0.0 0.89 9.3 0.0 2.4 1 1 0 2 2 2 2 Alpha/beta hydrolase family HEM4 PF02602.10 CCD24900.1 - 2e-40 138.4 0.0 2.2e-40 138.3 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD DUF3962 PF13111.1 CCD24900.1 - 0.0053 16.1 0.2 0.18 11.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3962) PIF1 PF05970.9 CCD24900.1 - 0.028 13.3 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase Oxidored_FMN PF00724.15 CCD24901.1 - 3e-123 411.1 0.0 3.4e-123 410.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family GMP_synt_C PF00958.17 CCD24902.1 - 2.3e-41 139.3 0.0 5.4e-41 138.2 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 CCD24902.1 - 4.2e-40 137.2 0.0 8.3e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.12 CCD24902.1 - 1.9e-08 33.5 0.0 3.6e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 CCD24902.1 - 1.4e-06 27.8 0.1 6.2e-06 25.7 0.0 2.2 2 1 0 2 2 2 1 Peptidase C26 PAPS_reduct PF01507.14 CCD24902.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family QueC PF06508.8 CCD24902.1 - 0.013 14.7 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.9 CCD24902.1 - 0.027 13.9 0.0 0.068 12.6 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 CCD24902.1 - 0.037 12.5 0.0 0.073 11.6 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase Arginosuc_synth PF00764.14 CCD24902.1 - 0.07 12.1 0.1 0.11 11.4 0.1 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase DnaJ PF00226.26 CCD24903.1 - 5e-27 93.4 6.2 1e-26 92.4 4.3 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CCD24903.1 - 3.4e-15 55.8 20.7 5.7e-15 55.1 14.4 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 CCD24903.1 - 8.9e-14 51.1 0.0 9.9e-12 44.5 0.0 2.5 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 CCD24903.1 - 0.046 13.4 9.3 0.23 11.1 0.7 2.2 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family CytoC_RC PF02276.13 CCD24903.1 - 0.27 10.2 2.6 0.41 9.7 1.8 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit Menin PF05053.8 CCD24904.1 - 0.16 10.1 2.8 0.17 10.0 1.9 1.0 1 0 0 1 1 1 0 Menin BRO1 PF03097.13 CCD24905.1 - 6.1e-83 278.6 8.3 6.1e-83 278.6 5.8 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CCD24905.1 - 2.9e-32 111.8 20.7 2.9e-32 111.8 14.4 2.6 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV IPPT PF01715.12 CCD24906.1 - 1.2e-85 286.5 0.1 1.8e-85 286.0 0.1 1.2 1 0 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 CCD24906.1 - 5e-06 27.3 0.1 2.6e-05 25.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 CCD24906.1 - 3.4e-05 23.1 0.1 0.00031 20.0 0.0 2.5 3 0 0 3 3 3 1 Isopentenyl transferase AAA_18 PF13238.1 CCD24906.1 - 0.00016 22.0 0.5 0.0013 18.9 0.1 2.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCD24906.1 - 0.00093 18.3 0.3 0.023 13.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 CCD24906.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCD24906.1 - 0.014 15.5 0.1 0.77 9.9 0.0 2.7 1 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CCD24906.1 - 0.034 14.3 0.1 0.14 12.3 0.0 2.1 2 0 0 2 2 1 0 RNA helicase DUF258 PF03193.11 CCD24906.1 - 0.036 13.2 0.0 0.069 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Las1 PF04031.8 CCD24906.1 - 0.044 13.4 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Las1-like AAA_25 PF13481.1 CCD24906.1 - 0.047 13.0 0.1 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 CCD24906.1 - 0.051 12.4 0.3 0.088 11.6 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.18 CCD24906.1 - 0.18 11.1 0.5 0.52 9.6 0.4 1.8 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.22 CCD24906.1 - 6.8 6.9 6.0 5.2 7.3 1.5 2.5 2 1 0 2 2 2 0 ABC transporter WD40 PF00400.27 CCD24907.1 - 3.1e-35 118.7 7.1 1.2e-07 31.3 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 CCD24907.1 - 5.5e-25 87.1 0.2 1.4e-24 85.8 0.1 1.8 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CCD24907.1 - 4.3e-07 28.4 10.7 0.002 16.3 0.3 3.9 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Hyphal_reg_CWP PF11765.3 CCD24908.1 - 1.2e-12 47.2 11.9 1.2e-12 47.2 8.3 1.5 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal BPL_C PF02237.12 CCD24908.1 - 0.083 12.5 0.0 0.93 9.2 0.0 2.6 1 1 1 2 2 2 0 Biotin protein ligase C terminal domain Mtc PF03820.12 CCD24909.1 - 5e-119 396.5 0.3 5.6e-119 396.3 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier V_ATPase_I PF01496.14 CCD24910.1 - 3.3e-289 961.0 8.1 3.8e-289 960.8 5.6 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3487 PF11990.3 CCD24910.1 - 2.8 7.3 5.9 0.76 9.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) WD40 PF00400.27 CCD24911.1 - 3.8e-32 108.9 20.0 1e-08 34.6 0.5 7.6 7 3 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 CCD24911.1 - 9.9e-06 23.9 1.2 0.019 13.0 0.1 2.4 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Neisseria_PilC PF05567.6 CCD24911.1 - 0.025 13.6 0.0 0.077 12.0 0.0 1.8 1 1 1 2 2 2 0 Neisseria PilC beta-propeller domain DUF2205 PF10224.4 CCD24911.1 - 0.055 13.0 0.5 0.14 11.7 0.3 1.6 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Sema PF01403.14 CCD24911.1 - 0.079 11.4 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Sema domain DivIC PF04977.10 CCD24911.1 - 0.095 12.1 0.0 0.3 10.6 0.1 1.8 2 0 0 2 2 2 0 Septum formation initiator PQQ_3 PF13570.1 CCD24911.1 - 0.14 12.4 0.0 1.1 9.6 0.0 2.6 2 0 0 2 2 2 0 PQQ-like domain Pkinase PF00069.20 CCD24912.1 - 2e-58 197.6 0.3 1.4e-54 184.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24912.1 - 1.6e-18 66.6 0.0 7.9e-18 64.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 CCD24912.1 - 0.02 14.6 0.0 0.041 13.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF605 PF04652.11 CCD24912.1 - 0.029 13.7 50.3 0.11 11.8 13.6 2.1 2 0 0 2 2 2 0 Vta1 like Kinase-like PF14531.1 CCD24912.1 - 0.044 12.7 0.0 0.093 11.6 0.0 1.5 1 1 0 1 1 1 0 Kinase-like TBCA PF02970.11 CCD24914.1 - 3.3e-28 97.6 11.9 3.9e-28 97.3 8.3 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A MutS_III PF05192.13 CCD24914.1 - 0.0031 17.3 0.1 0.0037 17.0 0.1 1.1 1 0 0 1 1 1 1 MutS domain III Cytochrom_C_2 PF01322.15 CCD24914.1 - 0.0084 16.6 1.0 0.011 16.2 0.7 1.2 1 0 0 1 1 1 1 Cytochrome C' Atg14 PF10186.4 CCD24914.1 - 0.016 14.1 2.6 0.021 13.8 1.8 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Snf7 PF03357.16 CCD24914.1 - 0.049 13.0 6.7 0.054 12.8 4.7 1.0 1 0 0 1 1 1 0 Snf7 Fzo_mitofusin PF04799.8 CCD24914.1 - 0.081 12.2 2.4 0.097 12.0 1.6 1.2 1 0 0 1 1 1 0 fzo-like conserved region Mnd1 PF03962.10 CCD24914.1 - 0.11 12.1 7.1 0.13 11.9 4.9 1.1 1 0 0 1 1 1 0 Mnd1 family AAA_13 PF13166.1 CCD24914.1 - 0.21 10.0 7.6 0.22 9.9 5.3 1.0 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 CCD24914.1 - 0.25 9.7 8.1 0.27 9.5 5.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) EspB PF05802.6 CCD24914.1 - 0.31 9.9 2.7 1.4 7.8 0.3 2.0 1 1 1 2 2 2 0 Enterobacterial EspB protein DUF1910 PF08928.5 CCD24914.1 - 0.36 10.8 3.6 0.54 10.3 2.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) Spc7 PF08317.6 CCD24914.1 - 0.72 8.4 9.7 0.86 8.2 6.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Phage_GP20 PF06810.6 CCD24914.1 - 0.74 9.2 13.8 17 4.8 9.6 2.0 1 1 0 1 1 1 0 Phage minor structural protein GP20 TBPIP PF07106.8 CCD24914.1 - 0.93 9.0 10.0 3.6 7.0 6.5 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF3166 PF11365.3 CCD24914.1 - 0.94 9.9 6.5 0.11 12.9 0.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) APG6 PF04111.7 CCD24914.1 - 5.4 5.9 10.7 5.9 5.8 7.4 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CCD24914.1 - 5.6 6.5 10.3 8.9 5.8 7.1 1.3 1 1 0 1 1 1 0 IncA protein bZIP_1 PF00170.16 CCD24914.1 - 9.8 6.2 8.4 1.8 8.6 2.0 2.3 2 1 0 2 2 2 0 bZIP transcription factor ATP_bind_1 PF03029.12 CCD24916.1 - 2.2e-79 266.3 0.1 2.8e-79 265.9 0.1 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CCD24916.1 - 0.00047 19.6 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 CCD24916.1 - 0.00068 20.4 3.2 0.0016 19.2 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCD24916.1 - 0.0008 19.7 1.6 0.7 10.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CCD24916.1 - 0.011 15.7 0.0 0.06 13.3 0.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_19 PF13245.1 CCD24916.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 CCD24916.1 - 0.035 13.9 0.0 0.082 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CCD24916.1 - 0.046 12.4 0.3 0.088 11.5 0.0 1.5 2 0 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 CCD24916.1 - 0.089 12.9 0.0 0.26 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 CCD24916.1 - 0.12 11.9 0.1 0.4 10.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain NTP_transf_3 PF12804.2 CCD24917.1 - 0.00082 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 CCD24917.1 - 0.0013 18.1 1.0 0.0069 15.8 0.1 2.5 2 1 1 3 3 3 1 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 CCD24917.1 - 0.0035 15.9 1.9 0.025 13.1 0.1 2.1 1 1 1 2 2 2 2 L-fucokinase Hexapep_2 PF14602.1 CCD24917.1 - 0.34 10.4 3.0 7.2 6.2 0.3 2.6 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase Tir_receptor_C PF07489.6 CCD24917.1 - 9.1 5.9 17.1 6.6 6.4 0.6 2.4 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) C-terminus AAA PF00004.24 CCD24918.1 - 1e-42 145.4 0.0 2.1e-42 144.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCD24918.1 - 1e-06 28.8 1.1 3.4e-05 23.9 0.0 3.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CCD24918.1 - 1.1e-06 28.4 0.9 4.2e-05 23.2 0.1 3.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCD24918.1 - 2.6e-05 24.1 0.0 7.2e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CCD24918.1 - 8.8e-05 21.6 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCD24918.1 - 0.0001 22.4 0.6 0.006 16.7 0.0 2.7 2 1 1 3 3 2 1 AAA domain AAA_19 PF13245.1 CCD24918.1 - 0.00017 21.2 0.1 0.00036 20.2 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CCD24918.1 - 0.0006 20.6 0.9 0.0017 19.1 0.1 2.2 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CCD24918.1 - 0.0012 18.4 0.0 0.0024 17.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CCD24918.1 - 0.0019 18.3 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 CCD24918.1 - 0.002 16.8 0.1 0.0038 16.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 CCD24918.1 - 0.0043 16.4 0.7 0.037 13.4 0.3 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 CCD24918.1 - 0.0054 16.6 0.2 0.018 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCD24918.1 - 0.0057 15.8 0.2 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 CCD24918.1 - 0.0063 16.8 0.1 0.05 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CCD24918.1 - 0.0075 16.2 0.0 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCD24918.1 - 0.0078 15.6 0.1 0.0078 15.6 0.1 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 CCD24918.1 - 0.0096 15.5 0.3 0.022 14.3 0.2 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCD24918.1 - 0.01 15.7 0.0 0.03 14.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CCD24918.1 - 0.02 14.0 0.2 0.097 11.7 0.0 2.2 2 0 0 2 2 2 0 KaiC PhoH PF02562.11 CCD24918.1 - 0.032 13.4 0.2 0.072 12.3 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 CCD24918.1 - 0.036 13.1 0.9 0.12 11.4 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.12 CCD24918.1 - 0.059 12.2 0.1 0.14 11.0 0.1 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ResIII PF04851.10 CCD24918.1 - 0.061 13.1 0.2 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_3 PF07726.6 CCD24918.1 - 0.073 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCD24918.1 - 0.09 12.4 0.1 0.27 10.8 0.1 2.0 1 1 0 1 1 1 0 NACHT domain AAA_11 PF13086.1 CCD24918.1 - 0.19 11.2 4.1 0.82 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CCD24918.1 - 0.28 10.8 3.2 3.8 7.1 0.0 3.2 3 1 1 4 4 3 0 Archaeal ATPase Fib_alpha PF08702.5 CCD24918.1 - 0.47 10.5 3.8 1.1 9.3 2.6 1.7 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.1 CCD24918.1 - 2.7 8.2 10.2 6.6 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain HIT PF01230.18 CCD24919.1 - 2.4e-18 66.4 0.6 1.4e-17 63.9 0.2 2.1 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 CCD24919.1 - 4.8e-15 55.8 4.3 2.4e-14 53.5 3.0 2.0 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2H2_4 PF13894.1 CCD24919.1 - 0.023 14.9 1.7 0.023 14.9 1.2 2.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CCD24919.1 - 0.4 10.8 6.6 0.7 10.0 3.6 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) EF-hand_1 PF00036.27 CCD24920.1 - 2e-29 98.6 16.6 6.9e-08 31.2 1.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCD24920.1 - 1.1e-23 83.1 16.2 4.6e-14 52.3 2.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCD24920.1 - 1.1e-22 77.8 15.0 3.8e-07 29.4 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CCD24920.1 - 1.6e-18 66.0 16.9 8.9e-13 47.6 2.3 3.7 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CCD24920.1 - 1.3e-14 52.7 24.1 1.6e-06 27.2 0.2 5.3 4 2 1 5 5 5 3 EF hand EF-hand_9 PF14658.1 CCD24920.1 - 8.7e-12 44.7 0.2 9.2e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CCD24920.1 - 0.00027 20.6 7.0 0.095 12.4 0.2 2.8 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand UPF0231 PF06062.6 CCD24920.1 - 0.038 13.8 3.2 0.74 9.7 0.1 3.2 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0231) SPARC_Ca_bdg PF10591.4 CCD24920.1 - 0.099 12.6 3.8 2.6 8.0 0.3 2.3 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF4373 PF14297.1 CCD24920.1 - 0.12 12.6 1.7 5.7 7.3 0.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4373) VCBS PF13517.1 CCD24920.1 - 5.1 7.5 6.9 5.7 7.3 0.2 2.9 2 2 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TFR_dimer PF04253.10 CCD24921.1 - 8.1e-23 80.3 1.3 5.2e-22 77.7 0.3 2.3 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 CCD24921.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Acetyltransf_1 PF00583.19 CCD24922.1 - 1.5e-12 47.3 0.0 2.1e-12 46.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCD24922.1 - 2e-08 34.2 0.1 2.8e-08 33.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCD24922.1 - 6.7e-07 29.3 0.2 7.8e-07 29.1 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCD24922.1 - 1.2e-05 25.3 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCD24922.1 - 0.0043 16.9 0.0 0.0049 16.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCD24922.1 - 0.019 14.6 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.1 CCD24922.1 - 0.02 14.7 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FBD PF08387.5 CCD24922.1 - 0.032 13.7 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 FBD DUF4222 PF13973.1 CCD24922.1 - 0.06 12.7 0.1 3.5 7.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4222) DUF2962 PF11176.3 CCD24923.1 - 2.9e-48 163.3 7.5 3.5e-48 163.0 5.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Rhodanese PF00581.15 CCD24924.1 - 4.7e-17 62.3 0.0 9.8e-10 38.7 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain HAD_2 PF13419.1 CCD24924.1 - 0.056 13.6 0.1 0.22 11.7 0.0 1.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Clp1 PF06807.9 CCD24925.1 - 2.7e-17 63.1 0.0 4.8e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CCD24925.1 - 4.4e-07 29.7 0.0 8.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CCD24925.1 - 0.00091 19.1 0.4 0.005 16.7 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CCD24925.1 - 0.0049 16.3 0.0 0.016 14.6 0.0 1.9 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 CCD24925.1 - 0.011 16.1 0.0 0.071 13.6 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 CCD24925.1 - 0.019 14.4 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.1 CCD24925.1 - 0.044 14.0 2.9 0.41 10.9 1.9 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCD24925.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 CCD24925.1 - 0.11 12.6 0.0 0.38 10.9 0.0 2.0 1 0 0 1 1 1 0 RNA helicase Apc5 PF12862.2 CCD24926.1 - 2e-27 94.8 6.9 2e-27 94.8 4.8 3.0 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 Augurin PF15187.1 CCD24926.1 - 0.0094 15.8 0.2 0.059 13.2 0.0 2.3 3 0 0 3 3 3 1 Oesophageal cancer-related gene 4 TPR_8 PF13181.1 CCD24926.1 - 0.012 15.3 0.5 2.8 7.9 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat adh_short PF00106.20 CCD24929.1 - 3.5e-12 46.5 0.0 1e-11 45.0 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCD24929.1 - 0.001 18.8 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCD24929.1 - 0.089 12.4 0.0 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 KR domain Shikimate_DH PF01488.15 CCD24929.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase tRNA-synt_1 PF00133.17 CCD24930.1 - 1.4e-43 148.8 0.0 7e-35 120.1 0.0 2.8 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CCD24930.1 - 3.2e-20 72.1 0.2 7.5e-11 41.3 0.0 4.2 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CCD24930.1 - 8.1e-12 45.1 0.0 2.1e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CCD24930.1 - 4.1e-07 29.4 0.0 1.4e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF2079 PF09852.4 CCD24931.1 - 0.11 11.1 2.1 0.15 10.7 1.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) DAGAT PF03982.8 CCD24932.1 - 6.9e-81 271.1 0.4 4.1e-72 242.3 0.0 2.1 1 1 1 2 2 2 2 Diacylglycerol acyltransferase MOZ_SAS PF01853.13 CCD24933.1 - 6.3e-89 296.2 0.6 9.8e-89 295.5 0.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CCD24933.1 - 7e-21 73.6 0.6 1.6e-20 72.5 0.4 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Spc97_Spc98 PF04130.8 CCD24933.1 - 0.013 13.8 0.0 0.023 13.0 0.0 1.4 1 0 0 1 1 1 0 Spc97 / Spc98 family Acetyltransf_1 PF00583.19 CCD24933.1 - 0.035 14.1 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family TruD PF01142.13 CCD24934.1 - 1.1e-64 218.4 0.9 1.6e-60 204.8 0.0 3.6 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) RRM_5 PF13893.1 CCD24935.1 - 0.0081 15.9 0.0 0.026 14.3 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD24935.1 - 0.044 13.7 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mur_ligase_M PF08245.7 CCD24936.1 - 1.8e-06 28.1 0.9 1.5e-05 25.0 0.1 2.7 2 1 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CCD24936.1 - 0.0032 17.4 0.0 0.011 15.8 0.0 1.9 1 1 1 2 2 2 1 Mur ligase family, glutamate ligase domain Methyltransf_12 PF08242.7 CCD24937.1 - 2e-13 50.6 0.1 1.3e-12 48.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCD24937.1 - 7.4e-12 45.2 0.0 1.2e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCD24937.1 - 6.3e-07 29.8 0.0 2.1e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCD24937.1 - 7.5e-07 28.8 0.1 3.5e-06 26.6 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD24937.1 - 1.7e-06 28.3 0.0 6.8e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD24937.1 - 3.2e-06 27.6 0.0 1.9e-05 25.1 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCD24937.1 - 0.016 15.2 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 CCD24937.1 - 0.018 14.0 0.0 2.5 6.9 0.0 2.4 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family DUF3419 PF11899.3 CCD24937.1 - 0.047 12.4 0.0 0.08 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3419) DUF1749 PF08538.5 CCD24939.1 - 3.6e-97 324.9 0.0 4.2e-97 324.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 CCD24939.1 - 2.8e-11 43.7 0.0 3.3e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCD24939.1 - 2.2e-07 30.7 0.0 1e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD24939.1 - 1.8e-06 27.6 0.0 2.4e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCD24939.1 - 3.4e-05 23.1 0.0 8.3e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2305 PF10230.4 CCD24939.1 - 0.0011 18.3 0.3 0.011 15.1 0.1 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Ndr PF03096.9 CCD24939.1 - 0.0072 14.8 0.0 0.0099 14.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family SPA PF08616.5 CCD24939.1 - 0.028 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis Abhydrolase_2 PF02230.11 CCD24939.1 - 0.034 13.5 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Esterase PF00756.15 CCD24939.1 - 0.041 13.3 0.0 0.068 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 CCD24939.1 - 0.064 12.8 0.1 0.15 11.7 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 3) COesterase PF00135.23 CCD24939.1 - 0.068 11.8 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family LCAT PF02450.10 CCD24939.1 - 0.071 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 CCD24939.1 - 0.093 12.0 0.2 0.26 10.5 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) ABC_membrane_2 PF06472.10 CCD24940.1 - 2.8e-86 289.1 9.4 2.8e-86 289.1 6.5 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CCD24940.1 - 2.5e-13 50.4 0.0 9.2e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CCD24940.1 - 0.00054 19.2 0.5 0.025 13.8 0.3 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DEAD PF00270.24 CCD24940.1 - 0.0063 16.0 0.0 0.065 12.7 0.0 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 CCD24940.1 - 0.024 14.6 0.0 0.075 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain SbcCD_C PF13558.1 CCD24940.1 - 0.067 13.1 0.2 0.56 10.1 0.1 2.6 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Oxysterol_BP PF01237.13 CCD24941.1 - 2.7e-85 285.9 1.5 3.1e-85 285.7 1.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DHFR_1 PF00186.14 CCD24942.1 - 2.5e-28 98.6 0.0 5.1e-28 97.6 0.0 1.5 1 1 1 2 2 2 1 Dihydrofolate reductase chaperone_DMP PF10448.4 CCD24943.1 - 3.2e-17 62.7 0.3 3.9e-17 62.5 0.2 1.1 1 0 0 1 1 1 1 20S proteasome chaperone Ribosomal_L35Ae PF01247.13 CCD24944.1 - 4.7e-42 141.6 1.8 5.3e-42 141.5 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CCD24944.1 - 0.0031 17.3 0.0 2.7 7.9 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Pkinase PF00069.20 CCD24945.1 - 1.6e-65 220.8 0.0 3.4e-65 219.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24945.1 - 8.8e-38 129.8 0.0 1.5e-37 129.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD24945.1 - 3.7e-07 29.3 0.0 7.2e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 CCD24945.1 - 0.0079 15.5 0.0 0.022 14.0 0.0 1.7 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CCD24945.1 - 0.0082 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCD24945.1 - 0.014 14.4 0.0 0.025 13.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GrpE PF01025.14 CCD24946.1 - 1.7e-50 170.7 9.9 2.2e-50 170.4 6.9 1.1 1 0 0 1 1 1 1 GrpE Uds1 PF15456.1 CCD24946.1 - 0.00076 19.4 3.3 0.0016 18.4 2.3 1.5 1 0 0 1 1 1 1 Up-regulated During Septation TPD52 PF04201.10 CCD24946.1 - 0.031 14.0 7.4 0.043 13.5 5.1 1.2 1 0 0 1 1 1 0 Tumour protein D52 family YqfQ PF14181.1 CCD24946.1 - 0.044 13.8 5.4 0.073 13.1 3.7 1.4 1 0 0 1 1 1 0 YqfQ-like protein SYCE1 PF15233.1 CCD24946.1 - 0.06 13.2 9.1 0.085 12.7 6.3 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 OmpH PF03938.9 CCD24946.1 - 0.062 13.2 6.7 0.091 12.6 4.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF3926 PF13080.1 CCD24946.1 - 0.08 12.4 0.8 0.22 11.0 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Atg14 PF10186.4 CCD24946.1 - 0.089 11.7 2.9 0.12 11.3 2.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2229 PF09989.4 CCD24946.1 - 0.15 11.5 2.4 0.19 11.1 1.7 1.3 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) GAS PF13851.1 CCD24946.1 - 0.38 9.9 17.3 0.73 8.9 12.0 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 CCD24946.1 - 0.43 8.3 3.7 0.45 8.3 2.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF883 PF05957.8 CCD24946.1 - 0.93 9.9 5.7 0.68 10.3 2.5 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) PhoU PF01895.14 CCD24946.1 - 1.4 9.3 4.9 13 6.3 0.0 2.3 2 0 0 2 2 2 0 PhoU domain IncA PF04156.9 CCD24946.1 - 2.2 7.8 13.1 4.1 6.9 9.1 1.4 1 1 0 1 1 1 0 IncA protein Pkinase PF00069.20 CCD24947.1 - 4.8e-69 232.3 0.0 7.6e-69 231.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24947.1 - 1.1e-35 122.9 0.0 2.3e-35 121.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD24947.1 - 4.1e-09 35.8 0.0 7.2e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CCD24947.1 - 0.0072 15.2 0.0 0.012 14.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 CCD24947.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CCD24947.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 CCD24948.1 - 6.2e-05 22.7 7.9 0.0069 16.2 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40 PF00400.27 CCD24949.1 - 1.2e-06 28.1 6.5 0.0037 17.0 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat Mmp37 PF09139.6 CCD24950.1 - 6.7e-103 344.1 12.9 6.4e-95 317.9 3.2 2.8 2 1 1 3 3 3 2 Mitochondrial matrix Mmp37 DUF1691 PF07950.6 CCD24951.1 - 8.4e-26 90.0 1.4 3.1e-14 52.8 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) DUF4501 PF14946.1 CCD24951.1 - 0.075 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) NifU_N PF01592.11 CCD24953.1 - 1.9e-53 179.7 0.2 2.3e-53 179.4 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain RNA_pol_Rpb8 PF03870.10 CCD24954.1 - 1.8e-45 154.5 0.1 2.3e-45 154.1 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 DUF2407_C PF13373.1 CCD24955.1 - 1.5e-46 157.8 3.0 3.2e-46 156.7 2.1 1.6 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 CCD24955.1 - 2.2e-20 72.6 0.2 5.2e-20 71.4 0.2 1.7 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rep_N PF08724.5 CCD24955.1 - 0.011 15.2 0.1 0.018 14.6 0.0 1.2 1 0 0 1 1 1 0 Rep protein catalytic domain like Mito_carr PF00153.22 CCD24956.1 - 2.5e-67 222.6 0.7 4.8e-25 87.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 CCD24956.1 - 0.019 14.9 0.0 0.075 13.0 0.0 2.0 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family ATG22 PF11700.3 CCD24959.1 - 0.0028 16.2 0.0 0.003 16.1 0.0 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like COX6C PF02937.10 CCD24959.1 - 0.018 14.9 0.1 0.03 14.1 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIc Eno-Rase_FAD_bd PF07055.7 CCD24959.1 - 0.11 12.4 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Enoyl reductase FAD binding domain DUF1980 PF09323.5 CCD24959.1 - 4.9 6.8 10.6 2.1 8.0 3.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) RFC1 PF08519.7 CCD24960.1 - 5.4e-60 201.6 0.3 1.2e-57 194.0 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.24 CCD24960.1 - 4.6e-12 46.2 0.0 1.5e-11 44.5 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 CCD24960.1 - 1.7e-10 40.9 0.0 4.7e-10 39.4 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.10 CCD24960.1 - 8.9e-08 31.2 0.2 0.00044 19.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CCD24960.1 - 1.6e-05 25.0 0.0 9.8e-05 22.5 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCD24960.1 - 2.8e-05 24.9 2.7 7.3e-05 23.5 0.0 3.0 4 0 0 4 4 3 1 AAA domain RuvB_N PF05496.7 CCD24960.1 - 4e-05 22.7 0.0 9.1e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCD24960.1 - 0.00026 21.0 0.1 0.0069 16.3 0.0 3.0 4 0 0 4 4 4 1 AAA ATPase domain AAA_33 PF13671.1 CCD24960.1 - 0.0014 18.5 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCD24960.1 - 0.0055 17.0 0.0 0.02 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCD24960.1 - 0.0066 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 CCD24960.1 - 0.0096 16.0 0.0 0.034 14.3 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 CCD24960.1 - 0.012 15.4 0.0 0.15 11.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain PTCB-BRCT PF12738.2 CCD24960.1 - 0.022 14.6 0.0 0.084 12.7 0.0 2.1 1 0 0 1 1 1 0 twin BRCT domain AAA_5 PF07728.9 CCD24960.1 - 0.052 13.2 0.1 0.15 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) GRAB PF10375.4 CCD24961.1 - 1e-06 28.1 1.2 2.6e-06 26.8 0.8 1.8 1 0 0 1 1 1 1 GRIP-related Arf-binding domain CENP-F_leu_zip PF10473.4 CCD24961.1 - 0.001 18.8 24.2 0.001 18.8 16.8 5.0 1 1 4 5 5 5 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Rootletin PF15035.1 CCD24961.1 - 0.41 10.5 63.7 0.31 10.9 6.0 4.2 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion YqeY PF09424.5 CCD24962.1 - 1.4e-22 80.0 5.7 1.7e-22 79.8 3.9 1.1 1 0 0 1 1 1 1 Yqey-like protein Rapamycin_bind PF08771.6 CCD24962.1 - 0.024 14.7 2.9 0.1 12.7 0.4 2.5 2 1 1 3 3 3 0 Rapamycin binding domain PP2C_C PF07830.8 CCD24962.1 - 0.22 11.6 2.8 6.8 6.8 0.0 2.7 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF1764 PF08576.5 CCD24962.1 - 5.9 7.7 6.0 7.1 7.4 2.7 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) YEATS PF03366.11 CCD24964.1 - 3.4e-24 84.3 0.0 5.2e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 YEATS family YEATS PF03366.11 CCD24965.1 - 2.4e-22 78.4 0.1 1e-21 76.4 0.0 2.0 2 0 0 2 2 2 1 YEATS family TipAS PF07739.8 CCD24965.1 - 0.071 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 TipAS antibiotic-recognition domain WD40 PF00400.27 CCD24966.1 - 3.3e-34 115.5 28.0 2.5e-07 30.3 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat LXG PF04740.7 CCD24966.1 - 0.037 13.8 2.8 0.065 13.0 2.0 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily Cytochrom_D1 PF02239.11 CCD24966.1 - 0.093 11.0 0.7 9.1 4.4 0.0 2.9 3 0 0 3 3 3 0 Cytochrome D1 heme domain Linker_histone PF00538.14 CCD24967.1 - 4.2e-42 142.0 0.1 2.3e-20 72.4 0.0 2.6 2 0 0 2 2 2 2 linker histone H1 and H5 family Daxx PF03344.10 CCD24967.1 - 6.7 5.0 41.4 8.9 4.6 28.7 1.2 1 0 0 1 1 1 0 Daxx Family Dynamin_N PF00350.18 CCD24968.1 - 1.8e-41 141.7 0.1 1.8e-41 141.7 0.1 2.8 4 0 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.18 CCD24968.1 - 0.00036 20.4 0.2 0.007 16.3 0.1 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCD24968.1 - 0.00059 20.3 0.0 0.0022 18.4 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein HTH_18 PF12833.2 CCD24968.1 - 0.063 13.3 2.3 0.3 11.2 0.7 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain AAA_16 PF13191.1 CCD24968.1 - 0.09 12.7 0.0 0.26 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Bd3614_N PF14442.1 CCD24968.1 - 4.2 7.3 5.6 8.1 6.4 3.9 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal RNA_pol_N PF01194.12 CCD24969.1 - 2.1e-29 101.3 0.5 2.4e-29 101.1 0.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit YhfH PF14149.1 CCD24969.1 - 0.068 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 YhfH-like protein Chordopox_RPO7 PF05864.7 CCD24969.1 - 0.086 12.9 0.4 0.11 12.5 0.3 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) NAPRTase PF04095.11 CCD24970.1 - 6.7e-65 218.7 0.0 8.8e-65 218.3 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family RNA_pol_Rpb2_6 PF00562.23 CCD24971.1 - 1.3e-120 402.7 0.1 2.3e-120 401.8 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCD24971.1 - 8.5e-61 204.4 1.1 1.9e-60 203.2 0.8 1.6 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCD24971.1 - 3.5e-42 143.9 2.3 8.1e-42 142.7 1.6 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCD24971.1 - 1.8e-30 105.0 0.3 8.7e-30 102.8 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CCD24971.1 - 5.6e-27 93.3 1.8 1e-26 92.5 0.1 2.4 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CCD24971.1 - 7.1e-19 67.3 0.0 1.8e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CCD24971.1 - 1.3e-10 41.0 0.1 1.3e-10 41.0 0.1 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 CCD24971.1 - 0.0018 16.7 0.1 0.0037 15.6 0.1 1.4 1 0 0 1 1 1 1 Baculovirus Y142 protein ING PF12998.2 CCD24972.1 - 5.3 7.3 6.4 0.82 9.9 1.1 2.0 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Noc2 PF03715.8 CCD24973.1 - 5.6e-127 422.7 6.9 7.6e-127 422.2 4.0 1.9 2 0 0 2 2 2 1 Noc2p family DUF2765 PF10963.3 CCD24973.1 - 0.0066 16.3 0.1 0.021 14.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2765) MMR_HSR1 PF01926.18 CCD24974.1 - 1.6e-07 31.2 0.1 9.8e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCD24974.1 - 0.00012 21.3 0.0 0.00023 20.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCD24974.1 - 0.00015 21.2 0.6 0.058 12.8 0.1 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCD24974.1 - 0.0031 17.3 0.7 0.081 12.7 0.0 2.9 3 0 0 3 3 3 1 Dynamin family ABC_tran PF00005.22 CCD24974.1 - 0.019 15.2 0.0 0.044 14.0 0.0 1.7 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 CCD24974.1 - 0.046 13.4 0.1 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CCD24974.1 - 0.067 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 CCD24975.1 - 4.6e-46 156.3 0.0 7.8e-45 152.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD24975.1 - 9.8e-27 92.6 0.1 2.2e-26 91.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD24975.1 - 0.022 14.6 0.0 0.072 12.9 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 CCD24975.1 - 0.032 13.2 0.0 0.077 12.0 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MethyTransf_Reg PF10119.4 CCD24975.1 - 0.16 12.4 0.1 0.38 11.2 0.0 1.6 1 0 0 1 1 1 0 Predicted methyltransferase regulatory domain IGPD PF00475.13 CCD24976.1 - 4.2e-60 201.8 0.5 1.4e-59 200.1 0.4 1.7 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase SpoU_methylase PF00588.14 CCD24977.1 - 9e-24 83.9 0.0 1.9e-20 73.2 0.0 3.0 3 0 0 3 3 3 2 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 CCD24977.1 - 1.1e-14 54.3 0.1 2.2e-14 53.3 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Peptidase_C14 PF00656.17 CCD24979.1 - 4.4e-70 236.1 0.1 5.9e-70 235.7 0.1 1.1 1 0 0 1 1 1 1 Caspase domain Radical_SAM PF04055.16 CCD24980.1 - 4e-15 56.3 0.0 6.7e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DLH PF01738.13 CCD24981.1 - 3.9e-22 78.6 0.0 4.4e-22 78.4 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCD24981.1 - 0.00025 20.7 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCD24981.1 - 0.0044 16.2 0.0 0.01 15.0 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2305 PF10230.4 CCD24981.1 - 0.086 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) 6PF2K PF01591.13 CCD24981.1 - 0.093 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Pyr_redox_2 PF07992.9 CCD24982.1 - 3.8e-28 98.7 0.0 3e-18 66.4 0.0 4.2 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCD24982.1 - 5.7e-14 52.2 0.0 2.5e-12 47.0 0.0 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCD24982.1 - 4e-07 30.2 0.0 0.00066 19.7 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Fzo_mitofusin PF04799.8 CCD24982.1 - 0.16 11.3 2.5 0.12 11.7 0.2 1.8 2 0 0 2 2 2 0 fzo-like conserved region NAD_binding_9 PF13454.1 CCD24982.1 - 0.17 11.6 0.0 21 4.8 0.0 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding Ldh_1_N PF00056.18 CCD24983.1 - 1.5e-40 138.2 0.0 2.9e-40 137.3 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CCD24983.1 - 3e-36 124.7 0.1 4.1e-36 124.3 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CCD24983.1 - 0.00025 19.8 0.0 0.00081 18.1 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CCD24983.1 - 0.01 16.1 0.0 0.03 14.6 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Vps4_C PF09336.5 CCD24984.1 - 0.0078 16.0 1.7 1.2 9.0 0.6 2.4 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain DUF775 PF05603.7 CCD24984.1 - 0.016 14.7 0.6 0.023 14.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) DUF1926 PF09095.6 CCD24984.1 - 0.06 12.5 0.8 0.11 11.7 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1926) Pkinase PF00069.20 CCD24985.1 - 7.1e-63 212.1 0.0 9.2e-63 211.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD24985.1 - 7.8e-28 97.2 0.0 1e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCD24985.1 - 0.0012 18.5 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Phage_C PF12025.3 CCD24985.1 - 0.052 13.4 0.5 0.81 9.6 0.0 2.5 2 0 0 2 2 2 0 Phage protein C RXT2_N PF08595.6 CCD24985.1 - 1.1 9.0 9.1 2.3 8.0 6.3 1.4 1 0 0 1 1 1 0 RXT2-like, N-terminal TPP_enzyme_N PF02776.13 CCD24986.1 - 2.9e-31 108.2 0.0 5.3e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCD24986.1 - 2.2e-23 82.5 0.0 5.2e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCD24986.1 - 5.1e-13 48.8 0.0 1.2e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain NUC153 PF08159.7 CCD24986.1 - 0.093 12.3 0.1 11 5.7 0.0 2.9 2 0 0 2 2 2 0 NUC153 domain Ribosomal_60s PF00428.14 CCD24987.1 - 1.4e-21 76.6 10.9 1.7e-21 76.3 7.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_L13e PF01294.13 CCD24988.1 - 1.7e-72 242.6 5.0 2.2e-72 242.2 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e 4HBT_3 PF13622.1 CCD24988.1 - 0.065 12.9 0.2 0.086 12.5 0.1 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Ribosomal_S9 PF00380.14 CCD24989.1 - 8.7e-39 132.5 0.2 9.9e-39 132.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Glyco_trans_1_3 PF13528.1 CCD24989.1 - 0.076 12.1 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 Nckap1 PF09735.4 CCD24989.1 - 0.15 9.5 0.0 0.17 9.2 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein TACC PF05010.9 CCD24990.1 - 0.065 12.9 12.3 0.097 12.4 8.5 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) DUF1967 PF09269.6 CCD24990.1 - 0.22 11.2 5.4 7.8 6.2 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1967) Sialidase_penC PF12135.3 CCD24990.1 - 0.3 10.7 5.2 3.3 7.4 0.3 3.2 4 0 0 4 4 4 0 Sialidase enzyme penultimate C terminal domain DivIC PF04977.10 CCD24990.1 - 0.91 9.0 11.6 0.069 12.6 2.4 2.3 2 0 0 2 2 2 0 Septum formation initiator COX16 PF14138.1 CCD24990.1 - 4.1 7.6 8.7 1.4 9.1 3.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein COX16 IncA PF04156.9 CCD24990.1 - 9.9 5.7 9.9 16 5.0 6.8 1.4 1 0 0 1 1 1 0 IncA protein DEAD PF00270.24 CCD24991.1 - 5.5e-35 120.3 0.2 1.4e-34 119.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD24991.1 - 1.3e-23 82.6 0.0 3.4e-22 78.1 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD24991.1 - 2.5e-05 24.1 0.1 7.9e-05 22.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DNA_pol_viral_N PF00242.12 CCD24992.1 - 5.2 5.9 7.8 6.2 5.7 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Pilt PF15453.1 CCD24992.1 - 6.9 6.2 12.0 9.2 5.8 8.3 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions SRP1_TIP1 PF00660.12 CCD24993.1 - 2e-09 37.1 0.5 2e-09 37.1 0.3 2.1 1 1 1 2 2 2 1 Seripauperin and TIP1 family SOG2 PF10428.4 CCD24993.1 - 0.0074 14.9 10.4 0.0094 14.6 7.2 1.0 1 0 0 1 1 1 1 RAM signalling pathway protein DUF2564 PF10819.3 CCD24993.1 - 0.024 14.7 0.4 0.067 13.3 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) Alpha_GJ PF03229.8 CCD24993.1 - 0.16 12.3 0.3 0.16 12.3 0.2 2.5 2 1 0 2 2 2 0 Alphavirus glycoprotein J Rifin_STEVOR PF02009.11 CCD24993.1 - 1.3 8.6 4.6 1 8.9 0.5 2.0 2 0 0 2 2 2 0 Rifin/stevor family RIC1 PF07064.8 CCD24994.1 - 1.4e-08 34.5 0.8 8e-08 32.0 0.5 2.2 1 1 0 1 1 1 1 RIC1 DUF2122 PF09895.4 CCD24994.1 - 0.062 13.5 0.2 0.28 11.4 0.0 2.2 2 0 0 2 2 2 0 RecB-family nuclease (DUF2122) COX6B PF02297.12 CCD24995.1 - 1.6e-20 72.9 4.7 2e-20 72.5 3.3 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 CCD24995.1 - 0.095 12.1 1.3 0.16 11.4 0.9 1.4 1 0 0 1 1 1 0 APOBEC-like C-terminal domain UPF0203 PF05254.7 CCD24995.1 - 0.32 10.8 5.8 2.8 7.8 0.9 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) DNA_mis_repair PF01119.14 CCD24996.1 - 4e-11 42.4 0.1 9.3e-11 41.2 0.1 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CCD24996.1 - 2.1e-10 40.3 0.1 7.8e-10 38.5 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCD24996.1 - 1.1e-09 37.9 0.1 2.8e-09 36.6 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase EF-hand_6 PF13405.1 CCD24996.1 - 0.023 14.5 0.0 0.094 12.6 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain Nramp PF01566.13 CCD24997.1 - 2.9e-95 319.1 12.9 3.8e-95 318.6 9.0 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF4131 PF13567.1 CCD24997.1 - 4 6.8 10.4 0.53 9.6 1.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Bromodomain PF00439.20 CCD24998.1 - 4e-05 23.4 1.5 0.00037 20.3 1.0 2.6 1 1 0 1 1 1 1 Bromodomain HA2 PF04408.18 CCD24999.1 - 1.1e-26 92.8 0.0 5.1e-26 90.6 0.0 2.3 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCD24999.1 - 2.5e-16 59.5 0.0 9.3e-16 57.6 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCD24999.1 - 2e-14 53.2 0.0 4.7e-13 48.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD24999.1 - 4.2e-08 32.8 0.0 1.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCD24999.1 - 3e-05 24.1 0.3 0.00014 22.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CCD24999.1 - 0.00053 18.9 0.0 0.0011 17.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein KaiC PF06745.8 CCD24999.1 - 0.0075 15.4 0.2 0.0075 15.4 0.1 2.5 2 1 1 3 3 3 1 KaiC AAA_19 PF13245.1 CCD24999.1 - 0.099 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 CCD24999.1 - 0.16 11.5 0.0 0.42 10.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SNF2_N PF00176.18 CCD25000.1 - 1.1e-66 224.6 0.1 2e-66 223.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 CCD25000.1 - 4e-13 49.2 0.0 9.1e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 CCD25000.1 - 1.3e-09 37.8 0.0 3.1e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CCD25000.1 - 7.1e-09 35.3 6.5 1.3e-08 34.4 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCD25000.1 - 3.8e-07 29.6 4.2 6.7e-07 28.8 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD25000.1 - 7.8e-07 29.0 7.5 1.5e-06 28.1 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCD25000.1 - 1.2e-06 28.0 8.6 2.3e-06 27.2 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DEAD PF00270.24 CCD25000.1 - 2.9e-06 26.8 0.0 6.8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 CCD25000.1 - 6.7e-06 25.6 8.7 1.5e-05 24.5 6.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCD25000.1 - 0.0059 16.2 2.9 0.019 14.6 2.0 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCD25000.1 - 0.021 14.6 8.8 0.046 13.6 6.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 CCD25000.1 - 0.034 13.9 2.1 0.074 12.8 1.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FANCL_C PF11793.3 CCD25000.1 - 0.086 12.8 4.6 0.21 11.5 3.2 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 CCD25000.1 - 0.11 12.0 7.2 0.24 11.0 5.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 CCD25000.1 - 0.16 12.0 2.7 0.36 10.9 1.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger MIF4G_like PF09088.6 CCD25001.1 - 1.7e-58 197.1 1.0 4.7e-58 195.7 0.7 1.7 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 CCD25001.1 - 2.4e-36 125.2 1.7 6.6e-36 123.8 1.2 1.8 1 0 0 1 1 1 1 MIF4G like Ribosomal_L15e PF00827.12 CCD25002.1 - 4e-89 297.2 14.5 4.7e-89 297.0 10.0 1.0 1 0 0 1 1 1 1 Ribosomal L15 zf-C3HC4_3 PF13920.1 CCD25003.1 - 5.4e-06 25.9 12.0 9.5e-06 25.1 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) AICARFT_IMPCHas PF01808.13 CCD25004.1 - 2.6e-123 411.1 0.0 3.8e-123 410.5 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CCD25004.1 - 6.9e-24 83.6 0.0 1.5e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 MGS-like domain Oxidored_FMN PF00724.15 CCD25005.1 - 2.8e-116 388.2 0.0 3.2e-116 388.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family adh_short PF00106.20 CCD25006.1 - 2.9e-17 63.0 0.0 4.1e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCD25006.1 - 1.4e-10 41.1 0.0 2.7e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCD25006.1 - 4.2e-05 23.1 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 CCD25006.1 - 0.00084 19.1 0.0 0.0012 18.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCD25006.1 - 0.0026 17.7 0.0 0.018 15.0 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 CCD25006.1 - 0.12 11.1 0.2 1.1 8.1 0.0 2.3 2 1 0 2 2 2 0 RmlD substrate binding domain Aminotran_1_2 PF00155.16 CCD25007.1 - 1e-80 271.4 0.0 1.2e-80 271.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SNARE PF05739.14 CCD25008.1 - 6.2e-19 67.4 3.8 2.4e-18 65.5 2.6 2.1 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 CCD25008.1 - 1.3e-16 60.6 0.9 1.3e-16 60.6 0.6 4.1 3 1 1 4 4 4 1 Syntaxin Sed5p PF11416.3 CCD25008.1 - 1.5e-07 30.6 8.2 1.5e-07 30.6 5.7 2.2 2 0 0 2 2 2 1 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 CCD25008.1 - 0.011 15.5 1.5 0.011 15.5 1.1 2.3 2 1 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus MCPsignal PF00015.16 CCD25008.1 - 0.017 14.6 0.2 0.017 14.6 0.1 2.8 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF2422 PF10337.4 CCD25008.1 - 1.8 7.2 7.0 0.1 11.3 0.2 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2422) DUF1664 PF07889.7 CCD25008.1 - 3.5 7.4 11.9 0.43 10.3 0.3 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) Snf7 PF03357.16 CCD25009.1 - 2.4e-48 163.7 21.9 2.4e-48 163.7 15.1 2.0 1 1 1 2 2 2 1 Snf7 NuA4 PF09340.5 CCD25009.1 - 0.0053 16.3 0.5 0.0053 16.3 0.4 2.1 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Snapin_Pallidin PF14712.1 CCD25009.1 - 0.16 12.2 14.1 0.05 13.9 4.4 2.9 1 1 0 2 2 2 0 Snapin/Pallidin Sdh_cyt PF01127.17 CCD25010.1 - 3.6e-18 65.5 4.9 5.3e-18 65.0 3.4 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Abhydrolase_1 PF00561.15 CCD25011.1 - 5.4e-23 81.7 0.0 8.8e-23 81.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 CCD25011.1 - 2.8e-22 77.8 0.1 6.2e-22 76.7 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CCD25011.1 - 0.0005 20.0 0.0 0.00096 19.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCD25011.1 - 0.0029 17.3 0.0 0.025 14.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CCD25011.1 - 0.0049 16.3 0.1 2.9 7.2 0.0 2.4 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 CCD25011.1 - 0.0094 15.4 0.0 0.7 9.2 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Pkinase PF00069.20 CCD25012.1 - 1.7e-65 220.7 0.0 3.2e-65 219.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25012.1 - 5.5e-28 97.7 0.1 1.6e-20 73.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCD25012.1 - 0.00093 18.2 0.0 0.0027 16.7 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCD25012.1 - 0.056 12.4 0.1 3.3 6.7 0.1 2.4 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SR-25 PF10500.4 CCD25012.1 - 4.3 6.7 36.1 1.6 8.1 14.6 2.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DASH_Hsk3 PF08227.6 CCD25013.1 - 2e-17 63.0 2.9 2.4e-17 62.8 2.0 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like Synaptonemal_3 PF15191.1 CCD25013.1 - 0.01 15.5 0.2 0.014 15.1 0.1 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 GvpK PF05121.7 CCD25013.1 - 0.048 13.4 0.1 0.059 13.1 0.1 1.1 1 0 0 1 1 1 0 Gas vesicle protein K DUF4618 PF15397.1 CCD25013.1 - 0.053 12.8 0.9 0.062 12.6 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) UPF0449 PF15136.1 CCD25013.1 - 0.074 13.2 0.4 0.1 12.7 0.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 FTA4 PF13093.1 CCD25013.1 - 0.1 11.9 3.3 0.86 8.9 1.3 1.9 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 BLOC1_2 PF10046.4 CCD25013.1 - 0.13 12.4 1.1 0.16 12.0 0.8 1.2 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.7 CCD25013.1 - 0.22 11.9 1.3 0.31 11.4 0.9 1.2 1 0 0 1 1 1 0 SlyX FlxA PF14282.1 CCD25013.1 - 0.34 10.8 3.0 0.42 10.5 2.0 1.1 1 0 0 1 1 1 0 FlxA-like protein L31 PF09784.4 CCD25014.1 - 3.1e-43 146.0 5.5 7.4e-43 144.8 3.8 1.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L31 Cmc1 PF08583.5 CCD25015.1 - 5.1e-19 67.8 3.0 6.5e-19 67.4 2.1 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like SAE2 PF08573.5 CCD25015.1 - 0.088 13.5 0.9 0.14 12.9 0.6 1.3 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Adaptin_N PF01602.15 CCD25016.1 - 1.1e-133 446.3 15.6 1.4e-133 446.0 10.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCD25016.1 - 3.1e-21 76.0 1.6 3.1e-21 76.0 1.1 2.9 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCD25016.1 - 1.5e-13 50.7 0.8 4.1e-07 30.1 0.1 5.7 4 2 1 6 6 6 2 HEAT repeats HEAT PF02985.17 CCD25016.1 - 2e-09 36.7 0.8 0.014 15.3 0.0 5.3 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 CCD25016.1 - 0.013 16.0 0.2 6.2 7.4 0.0 4.5 4 1 0 4 4 4 0 HEAT-like repeat CLASP_N PF12348.3 CCD25016.1 - 0.051 12.9 1.8 3.7 6.8 0.0 3.5 3 1 0 3 3 3 0 CLASP N terminal Arm PF00514.18 CCD25016.1 - 0.27 11.1 1.4 25 4.8 0.1 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Peptidase_M3 PF01432.15 CCD25017.1 - 2.3e-136 455.5 0.0 3.4e-136 454.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 CCD25017.1 - 0.078 12.3 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Mur_ligase_M PF08245.7 CCD25018.1 - 4.6e-06 26.8 0.0 1.1e-05 25.5 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CCD25018.1 - 0.025 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain She2p PF11435.3 CCD25019.1 - 1.1e-78 263.3 15.2 1.4e-78 263.0 10.5 1.1 1 0 0 1 1 1 1 RNA binding protein She2p Ist1 PF03398.9 CCD25019.1 - 0.0054 16.1 0.8 0.013 14.8 0.2 2.0 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway Closter_coat PF01785.12 CCD25019.1 - 0.08 11.9 0.4 0.17 10.8 0.3 1.6 1 1 0 1 1 1 0 Closterovirus coat protein Myosin_head PF00063.16 CCD25020.1 - 1.5e-226 753.6 8.6 2.5e-226 752.9 6.0 1.4 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CCD25020.1 - 2.5e-48 164.0 0.9 1.4e-47 161.5 0.1 2.3 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 CCD25020.1 - 1e-11 44.0 0.0 2.1e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCD25020.1 - 5.2e-09 35.5 0.0 1.1e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCD25020.1 - 8.5e-07 28.3 0.0 2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 CCD25020.1 - 0.0033 17.5 0.1 0.013 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCD25020.1 - 0.019 14.0 0.0 0.057 12.5 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 CCD25020.1 - 0.021 14.1 0.1 5.3 6.3 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.1 CCD25020.1 - 0.039 13.9 0.2 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 CCD25020.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 CCD25020.1 - 0.08 13.7 0.0 0.29 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain IQ PF00612.22 CCD25020.1 - 0.75 9.6 14.4 1.4 8.7 4.3 2.8 1 1 1 2 2 2 0 IQ calmodulin-binding motif DUF4047 PF13256.1 CCD25020.1 - 2.1 8.3 7.2 0.2 11.6 1.1 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF4047) TPP_enzyme_N PF02776.13 CCD25021.1 - 9.8e-56 187.9 0.1 3.3e-55 186.2 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCD25021.1 - 6e-50 168.7 0.2 3.5e-48 163.0 0.0 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCD25021.1 - 2.3e-36 124.5 0.3 2e-35 121.5 0.2 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain His_Phos_1 PF00300.17 CCD25022.1 - 1.3e-17 64.3 0.0 2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DUF2590 PF10761.4 CCD25023.1 - 0.13 12.0 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2590) PGM_PMM_III PF02880.11 CCD25024.1 - 5.7e-26 90.7 0.0 8.8e-26 90.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CCD25024.1 - 1.4e-09 37.8 0.0 2.8e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Kinesin PF00225.18 CCD25025.1 - 2.3e-103 345.4 5.3 3.3e-103 344.9 3.0 1.7 1 1 1 2 2 2 1 Kinesin motor domain Fib_alpha PF08702.5 CCD25025.1 - 0.11 12.5 15.4 0.04 14.0 3.6 2.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Lzipper-MIP1 PF14389.1 CCD25025.1 - 0.6 10.2 10.9 1.7 8.8 0.2 3.4 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Striatin PF08232.7 CCD25025.1 - 2 8.7 9.8 0.54 10.5 3.5 2.4 2 0 0 2 2 2 0 Striatin family TMF_DNA_bd PF12329.3 CCD25025.1 - 2.1 8.2 19.7 4.7 7.1 0.4 4.6 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CCD25025.1 - 2.3 7.7 12.9 21 4.6 0.1 3.1 2 1 0 2 2 2 0 IncA protein DUF3589 PF12141.3 CCD25026.1 - 4.8e-86 288.9 1.8 1.1e-85 287.7 1.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) Asp PF00026.18 CCD25027.1 - 1.4e-105 353.0 0.0 1.7e-105 352.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCD25027.1 - 1.1e-09 38.4 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCD25027.1 - 1e-05 25.1 0.0 6.1e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 CCD25027.1 - 0.0041 17.5 0.0 0.54 10.8 0.0 3.0 2 1 0 2 2 2 1 Aspartyl protease Pkinase PF00069.20 CCD25028.1 - 1.3e-78 263.7 0.0 3.6e-78 262.3 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25028.1 - 4.8e-38 130.7 0.0 9.5e-38 129.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CCD25028.1 - 2.4e-25 88.4 3.9 2.6e-13 49.8 0.2 3.2 3 0 0 3 3 3 2 FHA domain Kinase-like PF14531.1 CCD25028.1 - 1.5e-05 24.0 0.0 2.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCD25028.1 - 2.2e-05 23.6 0.0 3.6e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD25028.1 - 0.00015 21.6 0.0 0.0087 15.8 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Mei5 PF10376.4 CCD25029.1 - 1.5e-26 93.2 18.7 1.5e-26 93.2 13.0 1.6 1 1 1 2 2 2 1 Double-strand recombination repair protein Homeobox PF00046.24 CCD25029.1 - 0.004 16.7 0.9 0.032 13.8 0.1 2.5 2 0 0 2 2 2 1 Homeobox domain BACK PF07707.10 CCD25029.1 - 0.019 14.7 2.4 1.3 8.8 0.2 2.7 1 1 1 2 2 2 0 BTB And C-terminal Kelch Mating_N PF12731.2 CCD25029.1 - 0.5 10.2 4.0 7.3 6.5 0.8 3.0 3 0 0 3 3 3 0 Mating-type protein beta 1 Tfb2 PF03849.9 CCD25030.1 - 1.8e-153 510.5 0.5 1.8e-153 510.5 0.3 1.3 2 0 0 2 2 2 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CCD25030.1 - 2.1e-05 24.2 0.0 7.4e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Ribonuclease_T2 PF00445.13 CCD25031.1 - 1.3e-36 125.9 0.3 1.3e-36 125.9 0.2 1.6 2 0 0 2 2 2 1 Ribonuclease T2 family WEMBL PF05701.6 CCD25032.1 - 0.0018 16.8 2.3 0.0027 16.2 1.6 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Tmemb_cc2 PF10267.4 CCD25032.1 - 0.002 16.7 11.0 0.0028 16.3 7.4 1.4 1 1 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein MAGSP PF03082.9 CCD25032.1 - 0.01 15.2 7.5 0.01 15.2 5.2 1.6 2 0 0 2 2 2 0 Male accessory gland secretory protein CENP-F_leu_zip PF10473.4 CCD25032.1 - 0.066 13.0 7.4 0.14 12.0 5.2 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF869 PF05911.6 CCD25032.1 - 0.83 7.8 12.5 0.28 9.3 6.5 1.4 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Nup54 PF13874.1 CCD25032.1 - 0.91 9.1 9.1 0.35 10.5 4.2 1.8 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 LsmAD PF06741.8 CCD25032.1 - 4.5 7.4 9.8 0.53 10.4 1.1 2.8 3 0 0 3 3 3 0 LsmAD domain IncA PF04156.9 CCD25032.1 - 5.5 6.5 8.8 0.29 10.6 2.4 1.5 2 0 0 2 2 2 0 IncA protein Y_phosphatase PF00102.22 CCD25033.1 - 3.9e-54 183.4 7.0 3.8e-52 176.9 2.2 3.1 3 0 0 3 3 3 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CCD25033.1 - 0.0011 19.2 0.1 0.0091 16.2 0.0 2.5 3 0 0 3 3 3 1 Tyrosine phosphatase family IBN_N PF03810.14 CCD25034.1 - 3.2e-17 62.2 0.5 1.1e-16 60.4 0.4 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CCD25034.1 - 0.0005 20.0 0.1 0.0005 20.0 0.1 4.7 3 1 0 4 4 4 1 Exportin 1-like protein Mog1 PF04603.7 CCD25034.1 - 0.027 14.4 0.1 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 Ran-interacting Mog1 protein NAPRTase PF04095.11 CCD25035.1 - 6.1e-69 232.0 0.0 7.9e-69 231.6 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family WD40 PF00400.27 CCD25036.1 - 3.8e-06 26.5 4.5 0.0022 17.7 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Linker_histone PF00538.14 CCD25037.1 - 5e-46 154.6 3.2 1.9e-24 85.5 0.2 2.8 2 0 0 2 2 2 2 linker histone H1 and H5 family Dicty_REP PF05086.7 CCD25037.1 - 0.0054 14.5 12.9 0.0083 13.9 9.0 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein DUF1911 PF08929.5 CCD25037.1 - 0.043 14.4 0.0 6.1 7.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) MSC PF09402.5 CCD25037.1 - 0.08 11.6 4.4 2.4 6.7 0.6 2.5 2 1 0 2 2 2 0 Man1-Src1p-C-terminal domain Corona_M PF01635.13 CCD25037.1 - 0.41 9.5 10.0 0.85 8.5 6.9 1.5 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein BSP_II PF05432.6 CCD25037.1 - 0.63 9.2 10.2 0.96 8.6 7.0 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TRF PF08558.5 CCD25038.1 - 6.5e-78 261.3 0.2 1.2e-77 260.4 0.2 1.4 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 CCD25038.1 - 4.7e-08 32.9 0.1 1.2e-07 31.6 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCD25038.1 - 8e-05 22.6 0.3 0.00023 21.2 0.2 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain UCR_Fe-S_N PF10399.4 CCD25038.1 - 0.00044 19.3 1.6 0.001 18.1 1.1 1.6 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal YEATS PF03366.11 CCD25039.1 - 4.6e-24 83.9 0.3 7.7e-24 83.2 0.2 1.4 1 0 0 1 1 1 1 YEATS family Daxx PF03344.10 CCD25040.1 - 1.3 7.4 25.4 1.8 6.9 17.6 1.1 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CCD25040.1 - 5.9 4.6 25.8 7.5 4.3 17.9 1.2 1 0 0 1 1 1 0 Nop14-like family DUF4551 PF15087.1 CCD25040.1 - 6.7 4.9 8.6 8.2 4.6 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DPPIV_N PF00930.16 CCD25041.1 - 4.5e-87 291.8 5.7 6.6e-87 291.3 3.9 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CCD25041.1 - 1.9e-52 177.5 0.1 3.9e-52 176.5 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCD25041.1 - 8e-08 32.1 0.0 1.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCD25041.1 - 4.1e-05 23.5 0.0 0.0011 18.8 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCD25041.1 - 0.0031 16.9 0.0 0.44 9.9 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase PAF-AH_p_II PF03403.8 CCD25041.1 - 0.021 13.1 0.0 0.22 9.8 0.0 2.2 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S15 PF02129.13 CCD25041.1 - 0.56 9.5 4.4 1 8.7 0.1 2.9 2 1 1 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) Ribosomal_L18p PF00861.17 CCD25042.1 - 4e-45 152.8 0.6 6.9e-45 152.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CCD25042.1 - 1.3e-32 112.2 1.6 1.3e-32 112.2 1.1 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 CCD25042.1 - 0.023 14.6 0.4 1.5 8.8 0.0 2.8 3 0 0 3 3 3 0 Threonine synthase N terminus CtaG_Cox11 PF04442.9 CCD25043.1 - 9.9e-59 197.4 0.1 2e-58 196.4 0.0 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Ribosomal_S19e PF01090.14 CCD25043.1 - 0.089 12.2 0.2 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein S19e XkdN PF08890.6 CCD25043.1 - 0.14 11.8 0.2 0.47 10.1 0.1 1.8 2 0 0 2 2 2 0 Phage XkdN-like protein Zn_clus PF00172.13 CCD25044.1 - 7e-06 25.8 8.3 1.7e-05 24.5 5.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NifU_N PF01592.11 CCD25045.1 - 1.1e-53 180.4 0.5 3.1e-53 179.0 0.1 1.7 2 0 0 2 2 2 1 NifU-like N terminal domain LRR_4 PF12799.2 CCD25046.1 - 0.0092 15.5 0.7 0.0092 15.5 0.5 6.9 6 2 2 8 8 8 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CCD25046.1 - 8.4 6.8 15.1 4.4 7.6 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich repeat PHD PF00628.24 CCD25047.1 - 5.3e-13 48.4 6.3 1.2e-12 47.3 4.3 1.6 1 0 0 1 1 1 1 PHD-finger PIP49_C PF12260.3 CCD25047.1 - 0.0082 15.5 0.5 0.015 14.7 0.3 1.5 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 zf-RING_2 PF13639.1 CCD25047.1 - 1.3 8.8 9.6 0.2 11.4 3.6 2.0 2 0 0 2 2 2 0 Ring finger domain WD40 PF00400.27 CCD25048.1 - 0.0023 17.7 3.8 7.4 6.6 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCD25048.1 - 0.01 15.7 0.1 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex BBS2_Mid PF14783.1 CCD25048.1 - 0.014 15.2 0.2 3.3 7.5 0.0 3.2 1 1 2 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 CCD25049.1 - 7.1e-67 225.2 0.0 1.2e-66 224.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25049.1 - 1.5e-38 132.3 0.0 2.5e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD25049.1 - 4.1e-08 32.5 0.0 7.6e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCD25049.1 - 0.0084 15.8 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCD25049.1 - 0.018 14.1 0.3 0.062 12.3 0.2 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Oxysterol_BP PF01237.13 CCD25050.1 - 4.9e-93 311.4 1.2 5.4e-93 311.3 0.8 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Nop53 PF07767.6 CCD25051.1 - 5.4e-83 279.1 45.6 6.6e-83 278.8 31.6 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) ACPS PF01648.15 CCD25052.1 - 9.6e-16 57.6 0.0 2.1e-15 56.5 0.0 1.5 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily APG5 PF04106.7 CCD25054.1 - 8.4e-38 129.8 1.3 1.3e-37 129.2 0.9 1.3 1 0 0 1 1 1 1 Autophagy protein Apg5 SGT1 PF07093.6 CCD25055.1 - 4.1e-36 124.5 22.0 7.7e-30 103.8 0.4 2.1 2 0 0 2 2 2 2 SGT1 protein Dna2 PF08696.6 CCD25055.1 - 0.0042 16.4 0.8 0.0073 15.6 0.1 1.8 2 0 0 2 2 2 1 DNA replication factor Dna2 Pkinase PF00069.20 CCD25056.1 - 2e-67 227.0 0.1 3.5e-67 226.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25056.1 - 5e-38 130.6 0.0 8e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD25056.1 - 3.7e-08 32.6 0.0 7e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCD25056.1 - 0.051 12.6 0.0 0.14 11.2 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 CCD25057.1 - 3.9e-48 159.6 21.2 9.6e-10 37.9 0.6 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCD25057.1 - 5.5e-05 22.1 2.4 0.059 12.1 0.0 4.0 1 1 3 4 4 4 2 Nup133 N terminal like DUF3086 PF11285.3 CCD25057.1 - 0.008 15.0 0.0 0.017 13.9 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3086) DUF3859 PF12975.2 CCD25057.1 - 0.063 12.9 0.0 1.3 8.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3859) DUF1258 PF06869.7 CCD25057.1 - 0.099 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) SprB PF13573.1 CCD25057.1 - 0.98 9.0 4.1 0.4 10.3 0.4 2.1 2 0 0 2 2 2 0 SprB repeat PTPA PF03095.10 CCD25058.1 - 6.6e-116 386.6 0.4 7.6e-116 386.4 0.3 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein DUF433 PF04255.9 CCD25058.1 - 0.012 15.0 0.1 0.6 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF433) APG6 PF04111.7 CCD25059.1 - 4.9e-105 351.0 6.7 7.7e-105 350.4 4.7 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 TPR_2 PF07719.12 CCD25059.1 - 0.0081 15.9 1.0 2.2 8.3 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCD25059.1 - 0.046 14.1 1.0 1.9 9.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCD25059.1 - 0.049 13.4 0.5 1.9 8.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Tweety PF04906.8 CCD25059.1 - 0.079 11.3 1.5 0.17 10.2 1.1 1.6 1 0 0 1 1 1 0 Tweety V_ATPase_I PF01496.14 CCD25059.1 - 0.089 10.6 5.7 0.14 9.9 4.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Corona_S2 PF01601.11 CCD25059.1 - 0.11 10.6 8.5 0.12 10.4 5.2 1.5 1 1 0 1 1 1 0 Coronavirus S2 glycoprotein TPR_7 PF13176.1 CCD25059.1 - 0.11 12.3 1.1 2.2 8.3 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Herpes_UL6 PF01763.11 CCD25059.1 - 0.31 9.1 7.0 0.45 8.6 4.8 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like Ax_dynein_light PF10211.4 CCD25059.1 - 0.32 10.7 12.9 0.045 13.5 5.5 2.0 2 0 0 2 2 2 0 Axonemal dynein light chain Reo_sigmaC PF04582.7 CCD25059.1 - 1.7 7.7 6.3 0.49 9.5 1.5 2.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein OmpH PF03938.9 CCD25059.1 - 2.1 8.2 12.9 40 4.1 8.9 2.2 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF342 PF03961.8 CCD25059.1 - 7 4.9 16.6 8.6 4.6 6.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DEAD PF00270.24 CCD25060.1 - 1.2e-46 158.2 0.0 2.6e-45 153.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD25060.1 - 8.9e-28 95.9 0.1 2.8e-27 94.3 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD25060.1 - 0.0063 16.3 0.0 0.023 14.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 CCD25060.1 - 0.024 13.7 0.4 0.049 12.7 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit MethyTransf_Reg PF10119.4 CCD25060.1 - 0.16 12.4 0.4 0.52 10.8 0.0 2.0 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain Mit_ribos_Mrp51 PF11709.3 CCD25061.1 - 1.3e-74 251.2 0.6 1.6e-74 250.9 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit NUDIX PF00293.23 CCD25062.1 - 5.5e-27 94.0 0.0 7.8e-27 93.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Reo_sigmaC PF04582.7 CCD25063.1 - 0.0051 16.0 6.0 0.047 12.8 1.3 2.4 1 1 1 2 2 2 2 Reovirus sigma C capsid protein PAS_10 PF13596.1 CCD25063.1 - 0.19 11.9 7.1 11 6.2 0.1 4.4 2 1 1 3 3 3 0 PAS domain Cortex-I_coil PF09304.5 CCD25063.1 - 1.3 9.0 55.2 0.31 11.0 7.5 5.4 3 2 3 6 6 6 0 Cortexillin I, coiled coil HAUS-augmin3 PF14932.1 CCD25063.1 - 2.5 7.2 44.0 0.077 12.1 7.8 3.8 3 1 0 3 3 3 0 HAUS augmin-like complex subunit 3 Baculo_PEP_C PF04513.7 CCD25063.1 - 3.2 7.5 17.2 0.87 9.4 0.4 4.5 3 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Peptidase_C14 PF00656.17 CCD25064.1 - 4e-67 226.5 0.0 5e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Hist_deacetyl PF00850.14 CCD25065.1 - 1.9e-64 217.8 0.1 1.9e-64 217.8 0.1 1.6 2 0 0 2 2 2 1 Histone deacetylase domain RhoGAP PF00620.22 CCD25066.1 - 1.8e-35 121.8 1.7 2.8e-35 121.1 0.1 2.2 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 CCD25066.1 - 1.7e-09 37.8 0.3 8.5e-09 35.5 0.2 2.3 1 0 0 1 1 1 1 PH domain PX PF00787.19 CCD25066.1 - 0.0012 18.5 1.4 0.0037 17.0 0.3 2.3 2 0 0 2 2 2 1 PX domain PH_11 PF15413.1 CCD25066.1 - 0.0056 16.9 0.5 0.0056 16.9 0.3 4.0 4 1 0 4 4 4 1 Pleckstrin homology domain TFIIA PF03153.8 CCD25067.1 - 6.6e-60 203.9 19.1 6.1e-34 118.5 4.5 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit DUF2040 PF09745.4 CCD25067.1 - 0.058 13.2 2.0 0.12 12.1 1.1 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 55 (DUF2040) Presenilin PF01080.12 CCD25067.1 - 0.075 11.8 3.0 0.11 11.3 2.1 1.2 1 0 0 1 1 1 0 Presenilin Polyhedrin PF00738.13 CCD25067.1 - 0.075 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Polyhedrin Na_trans_assoc PF06512.8 CCD25067.1 - 0.41 10.5 11.4 0.44 10.4 7.4 1.3 1 1 0 1 1 1 0 Sodium ion transport-associated DUF465 PF04325.8 CCD25067.1 - 1.9 8.2 7.9 4.8 6.9 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF465) Cwf_Cwc_15 PF04889.7 CCD25067.1 - 5.2 6.7 12.1 8.4 6.0 8.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein 2-Hacid_dh_C PF02826.14 CCD25068.1 - 2.8e-34 117.7 0.0 5.1e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCD25068.1 - 0.033 13.6 0.0 0.049 13.0 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain PEX11 PF05648.9 CCD25069.1 - 3.6e-05 23.1 4.1 3.6e-05 23.1 2.9 2.0 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) Pep_M12B_propep PF01562.14 CCD25069.1 - 0.092 12.5 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Reprolysin family propeptide Arginase PF00491.16 CCD25070.1 - 3.8e-72 242.8 0.0 4.4e-72 242.6 0.0 1.0 1 0 0 1 1 1 1 Arginase family GDPD PF03009.12 CCD25071.1 - 2.4e-76 256.6 0.8 5.9e-76 255.3 0.0 2.2 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 CCD25071.1 - 1.1e-27 96.2 2.8 3.7e-10 39.9 0.6 4.3 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) SPX PF03105.14 CCD25071.1 - 2.1e-25 90.0 27.4 5.1e-16 59.2 6.9 3.8 5 0 0 5 5 5 2 SPX domain Ank_4 PF13637.1 CCD25071.1 - 4.3e-24 84.4 0.0 3.3e-06 27.4 0.0 5.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 CCD25071.1 - 6.6e-23 79.3 1.6 0.0008 19.0 0.0 7.3 7 0 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.1 CCD25071.1 - 3.3e-19 67.0 1.0 0.0053 16.8 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 CCD25071.1 - 3.7e-19 68.3 0.1 3.7e-05 23.8 0.0 5.4 3 2 2 5 5 5 4 Ankyrin repeats (many copies) ABC1 PF03109.11 CCD25072.1 - 1.4e-20 73.4 0.0 5.5e-20 71.5 0.0 2.0 2 1 0 2 2 2 1 ABC1 family Arf PF00025.16 CCD25073.1 - 8e-76 253.1 0.1 9e-76 252.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCD25073.1 - 2.3e-11 43.2 0.0 2.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CCD25073.1 - 4e-11 42.5 0.0 4.6e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 CCD25073.1 - 2.2e-10 40.0 0.0 2.7e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CCD25073.1 - 6.2e-10 38.3 0.4 2.2e-06 26.6 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CCD25073.1 - 2.1e-09 37.9 0.0 2.9e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CCD25073.1 - 1.5e-05 24.5 0.2 0.00024 20.5 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCD25073.1 - 0.00034 20.5 0.0 0.00049 20.0 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CCD25073.1 - 0.00078 19.7 0.4 0.0029 17.8 0.3 1.7 1 1 0 1 1 1 1 ABC transporter ArgK PF03308.11 CCD25073.1 - 0.004 15.9 1.1 0.25 10.0 0.2 2.8 2 1 0 2 2 2 1 ArgK protein cobW PF02492.14 CCD25073.1 - 0.09 12.2 0.5 4.5 6.6 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 CCD25073.1 - 0.18 11.2 0.5 0.55 9.6 0.1 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Soyouz_module PF14313.1 CCD25074.1 - 0.087 12.3 0.3 0.19 11.3 0.2 1.5 1 0 0 1 1 1 0 N-terminal region of Paramyxovirinae phosphoprotein (P) Oxidored-like PF09791.4 CCD25075.1 - 5.3e-25 86.6 4.0 1.2e-24 85.4 2.8 1.7 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal HSP70 PF00012.15 CCD25076.1 - 1.4e-185 617.7 3.2 2.6e-185 616.8 2.3 1.4 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCD25076.1 - 4.2e-11 42.0 0.1 1.9e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CCD25076.1 - 4.8e-06 26.4 1.1 0.00045 20.0 0.0 3.7 3 1 0 3 3 3 1 Cell division protein FtsA Ketoacyl-synt_C PF02801.17 CCD25076.1 - 0.042 13.6 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain NLE PF08154.7 CCD25076.1 - 0.073 13.0 0.1 0.23 11.4 0.1 1.9 1 0 0 1 1 1 0 NLE (NUC135) domain Trans_reg_C PF00486.23 CCD25076.1 - 0.097 12.5 0.0 0.31 10.9 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Endonuc_Holl PF10107.4 CCD25076.1 - 2.3 7.8 7.7 0.46 10.1 0.1 2.9 3 0 0 3 3 3 0 Endonuclease related to archaeal Holliday junction resolvase GYF PF02213.11 CCD25077.1 - 1.8e-19 69.0 2.3 5e-19 67.6 1.1 2.2 2 0 0 2 2 2 1 GYF domain DUF4339 PF14237.1 CCD25077.1 - 0.01 15.3 1.2 0.027 14.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4339) tRNA-synt_2 PF00152.15 CCD25078.1 - 5.5e-113 377.1 0.1 7.7e-113 376.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCD25078.1 - 1e-08 34.8 0.0 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CCD25078.1 - 0.0017 17.9 0.1 0.61 9.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 CCD25078.1 - 0.016 14.3 0.0 0.14 11.2 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Lactamase_B_2 PF12706.2 CCD25079.1 - 7.3e-30 103.9 0.2 1.1e-29 103.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CCD25079.1 - 4.8e-12 45.8 0.0 9.2e-12 44.9 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain WD40 PF00400.27 CCD25080.1 - 6.5e-07 28.9 0.2 0.0016 18.2 0.0 3.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Drc1-Sld2 PF11719.3 CCD25081.1 - 0.013 14.6 0.2 0.015 14.4 0.2 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein DUF770 PF05591.7 CCD25081.1 - 0.021 14.3 1.1 0.021 14.3 0.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF770) Rad4 PF03835.10 CCD25082.1 - 5e-12 45.4 1.4 1.6e-11 43.7 1.0 2.0 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 CCD25082.1 - 2.3e-10 40.6 0.1 4.7e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily zinc-ribbons_6 PF07191.7 CCD25082.1 - 0.0059 16.3 3.6 0.01 15.6 1.3 2.2 2 0 0 2 2 2 1 zinc-ribbons Sec62 PF03839.11 CCD25083.1 - 1.9e-60 204.1 0.9 1.9e-60 204.1 0.6 1.8 1 1 1 2 2 2 1 Translocation protein Sec62 MARVEL PF01284.18 CCD25083.1 - 0.09 12.5 3.0 5.5 6.8 3.5 2.4 2 1 0 2 2 2 0 Membrane-associating domain UPF0242 PF06785.6 CCD25083.1 - 0.25 10.0 1.5 0.42 9.2 1.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF3309 PF11752.3 CCD25083.1 - 0.76 9.6 11.0 1.6 8.5 7.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) SLAC1 PF03595.12 CCD25084.1 - 5e-77 258.7 33.3 6e-77 258.4 23.1 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Pyr_redox_2 PF07992.9 CCD25085.1 - 4.3e-42 144.2 0.3 7.8e-42 143.4 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CCD25085.1 - 1.6e-36 124.6 0.5 2.9e-34 117.3 0.1 3.1 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CCD25085.1 - 8.5e-20 70.9 7.0 9.6e-20 70.7 0.5 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCD25085.1 - 4.3e-10 40.0 0.0 1.8e-08 34.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCD25085.1 - 2e-06 26.5 4.1 0.37 9.2 0.3 3.9 3 1 1 4 4 4 3 HI0933-like protein FAD_oxidored PF12831.2 CCD25085.1 - 3e-06 26.5 0.2 1.3e-05 24.5 0.0 1.8 1 1 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 CCD25085.1 - 1.6e-05 23.9 0.0 2.5e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.16 CCD25085.1 - 3.2e-05 23.5 0.1 0.00027 20.5 0.0 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 CCD25085.1 - 0.0001 21.2 1.7 0.041 12.7 0.8 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A 3HCDH_N PF02737.13 CCD25085.1 - 0.00057 19.5 0.1 0.00057 19.5 0.0 1.7 2 0 0 2 2 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 CCD25085.1 - 0.0051 15.7 9.0 0.01 14.8 0.2 3.1 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 CCD25085.1 - 0.021 15.0 0.1 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 CCD25085.1 - 0.026 14.2 0.4 0.093 12.4 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 CCD25085.1 - 0.026 13.6 1.6 0.28 10.3 0.0 2.8 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CCD25085.1 - 0.037 13.3 0.1 0.077 12.3 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DNA_pol3_chi PF04364.8 CCD25085.1 - 0.05 13.4 0.0 0.091 12.6 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC ApbA PF02558.11 CCD25085.1 - 0.072 12.5 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 CCD25085.1 - 0.13 11.3 1.5 0.27 10.3 0.3 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 CCD25085.1 - 0.55 9.2 6.0 4.2 6.3 0.2 2.5 2 1 0 2 2 2 0 FAD binding domain FAD_binding_2 PF00890.19 CCD25085.1 - 4.3 6.0 10.8 0.084 11.7 1.6 2.4 4 0 0 4 4 4 0 FAD binding domain NAD_binding_8 PF13450.1 CCD25085.1 - 5.6 7.0 6.5 0.31 11.1 0.4 2.0 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Ribosomal_S6e PF01092.14 CCD25086.1 - 1.1e-61 206.0 0.7 1.8e-61 205.3 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e SRF-TF PF00319.13 CCD25087.1 - 9.4e-24 82.4 0.0 2.4e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ceramidase PF05875.7 CCD25088.1 - 5.7e-94 314.1 10.5 7.1e-94 313.8 7.3 1.1 1 0 0 1 1 1 1 Ceramidase DUF2660 PF10859.3 CCD25088.1 - 0.018 15.2 0.0 0.037 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF1129 PF06570.6 CCD25088.1 - 1.7 7.8 6.1 2.5 7.3 0.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) DUF1056 PF06341.6 CCD25088.1 - 2.9 7.9 7.8 0.83 9.7 0.2 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF1056) Sec16_C PF12931.2 CCD25089.1 - 3.9e-81 272.9 0.2 5.7e-81 272.3 0.1 1.3 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 CCD25089.1 - 4.1e-15 55.7 0.0 1.6e-14 53.8 0.0 2.2 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region AAA PF00004.24 CCD25090.1 - 1e-33 116.3 0.0 2.2e-33 115.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCD25090.1 - 4.3e-08 34.0 0.3 2.1e-07 31.7 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 CCD25090.1 - 5e-08 33.1 0.0 1.5e-07 31.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCD25090.1 - 1.7e-07 31.0 0.0 3.3e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 CCD25090.1 - 2.6e-06 27.7 0.3 3.9e-05 23.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCD25090.1 - 1e-05 25.5 0.2 0.00025 21.0 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CCD25090.1 - 2.2e-05 24.1 0.0 4.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CCD25090.1 - 5.8e-05 22.9 0.0 0.00013 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCD25090.1 - 0.00016 22.0 0.1 0.0005 20.3 0.0 1.9 2 0 0 2 2 1 1 ABC transporter AAA_25 PF13481.1 CCD25090.1 - 0.00018 20.9 0.0 0.0041 16.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CCD25090.1 - 0.00031 20.6 0.1 0.0013 18.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CCD25090.1 - 0.00032 20.4 0.2 0.0011 18.6 0.0 2.1 2 1 0 2 2 1 1 NACHT domain AAA_11 PF13086.1 CCD25090.1 - 0.00042 19.9 0.0 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CCD25090.1 - 0.00054 20.0 0.0 0.002 18.2 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_31 PF13614.1 CCD25090.1 - 0.00067 19.6 1.3 0.031 14.2 0.1 2.7 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 CCD25090.1 - 0.00099 18.1 0.3 0.0056 15.7 0.0 2.2 2 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 CCD25090.1 - 0.0013 17.6 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 CCD25090.1 - 0.0019 17.3 0.3 0.0056 15.8 0.0 1.9 3 0 0 3 3 2 1 Protein of unknown function, DUF258 KaiC PF06745.8 CCD25090.1 - 0.0026 16.9 0.8 0.44 9.6 0.0 2.5 1 1 1 2 2 2 1 KaiC AAA_23 PF13476.1 CCD25090.1 - 0.0029 17.9 0.1 0.0029 17.9 0.1 3.0 1 1 1 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CCD25090.1 - 0.0036 16.7 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.9 CCD25090.1 - 0.0037 17.1 0.0 0.013 15.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) MobB PF03205.9 CCD25090.1 - 0.0038 16.9 0.0 0.024 14.3 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B UPF0079 PF02367.12 CCD25090.1 - 0.0045 16.6 0.0 0.01 15.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 TAN PF11640.3 CCD25090.1 - 0.0051 16.5 0.5 0.019 14.7 0.1 2.2 2 0 0 2 2 1 1 Telomere-length maintenance and DNA damage repair AAA_24 PF13479.1 CCD25090.1 - 0.0086 15.6 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCD25090.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CCD25090.1 - 0.013 15.2 1.0 0.013 15.2 0.7 3.4 3 1 0 3 3 3 0 Archaeal ATPase Viral_helicase1 PF01443.13 CCD25090.1 - 0.017 14.6 0.0 0.042 13.3 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 CCD25090.1 - 0.017 14.5 0.0 0.31 10.4 0.0 2.5 2 1 1 3 3 3 0 AAA-like domain AAA_30 PF13604.1 CCD25090.1 - 0.019 14.5 0.0 0.042 13.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CCD25090.1 - 0.02 14.6 0.5 0.045 13.4 0.0 1.8 2 0 0 2 2 1 0 NTPase FtsK_SpoIIIE PF01580.13 CCD25090.1 - 0.022 14.2 0.0 0.054 12.9 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family KTI12 PF08433.5 CCD25090.1 - 0.029 13.5 1.6 0.11 11.6 0.0 2.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 RuvB_N PF05496.7 CCD25090.1 - 0.032 13.2 0.0 0.073 12.1 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 CCD25090.1 - 0.034 13.3 0.0 0.081 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Mg_chelatase PF01078.16 CCD25090.1 - 0.054 12.6 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CCD25090.1 - 0.12 11.4 0.0 0.35 9.9 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin DUF3535 PF12054.3 CCD25091.1 - 1.7e-147 491.6 0.2 8.7e-147 489.3 0.1 2.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 CCD25091.1 - 1.3e-78 263.8 0.0 2.4e-78 262.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 CCD25091.1 - 1.1e-14 53.0 5.0 0.45 10.7 0.0 8.5 8 0 0 8 8 8 5 HEAT repeat Helicase_C PF00271.26 CCD25091.1 - 1.2e-13 50.7 0.0 3.1e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT_EZ PF13513.1 CCD25091.1 - 1.2e-07 31.9 5.0 1.7 9.2 0.0 7.6 8 0 0 8 8 8 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CCD25091.1 - 3.9e-06 27.1 0.2 2.3 8.6 0.0 5.1 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Ribosomal_S4 PF00163.14 CCD25092.1 - 9e-27 93.3 1.6 1.4e-26 92.6 1.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCD25092.1 - 4.5e-14 51.6 0.2 1.7e-13 49.7 0.1 2.0 1 0 0 1 1 1 1 S4 domain Ribosomal_L21e PF01157.13 CCD25093.1 - 1.8e-46 155.9 5.6 1.2e-45 153.3 3.1 2.0 1 1 1 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.4 CCD25093.1 - 0.00022 20.6 0.1 0.00027 20.3 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Mt_ATP-synt_B PF05405.9 CCD25094.1 - 1e-51 174.6 9.0 1.2e-51 174.3 6.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SPA PF08616.5 CCD25095.1 - 0.095 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis Toxin_39 PF15500.1 CCD25095.1 - 0.6 10.2 2.6 2.5 8.3 1.1 2.6 2 1 0 2 2 2 0 Putative RNase-like toxin GPI2 PF06432.6 CCD25096.1 - 6.7e-61 206.1 18.6 7.7e-61 205.9 12.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase YwiC PF14256.1 CCD25096.1 - 0.17 11.9 0.0 0.17 11.9 0.0 2.6 1 1 0 2 2 2 0 YwiC-like protein SPC12 PF06645.8 CCD25096.1 - 3.7 7.4 9.2 0.063 13.0 0.9 2.2 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) GCR1_C PF12550.3 CCD25097.1 - 1e-21 76.5 5.0 1.3e-21 76.2 2.0 2.4 2 1 0 2 2 2 1 Transcriptional activator of glycolytic enzymes AAA PF00004.24 CCD25098.1 - 8.3e-41 139.2 0.0 3.5e-40 137.2 0.0 2.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCD25098.1 - 1.6e-05 24.8 1.2 0.0001 22.2 0.0 2.9 3 1 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCD25098.1 - 5e-05 23.4 0.2 0.0033 17.5 0.1 3.1 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCD25098.1 - 0.00012 21.2 0.0 0.00038 19.5 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Vps4_C PF09336.5 CCD25098.1 - 0.00013 21.7 0.1 0.00057 19.7 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_14 PF13173.1 CCD25098.1 - 0.00033 20.5 0.1 0.007 16.2 0.0 3.1 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.8 CCD25098.1 - 0.00058 18.6 0.0 0.00058 18.6 0.0 3.2 3 1 1 4 4 3 1 TIP49 C-terminus Mg_chelatase PF01078.16 CCD25098.1 - 0.0024 17.0 0.1 0.0076 15.4 0.1 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCD25098.1 - 0.0025 17.5 2.9 0.0069 16.1 0.0 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 CCD25098.1 - 0.0033 16.8 0.0 0.0074 15.7 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CCD25098.1 - 0.0066 16.1 0.0 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CCD25098.1 - 0.0074 17.1 4.0 0.038 14.8 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CCD25098.1 - 0.014 15.3 3.1 0.42 10.5 0.0 3.7 3 1 1 4 4 4 0 AAA domain AAA_16 PF13191.1 CCD25098.1 - 0.014 15.3 0.1 0.2 11.5 0.1 2.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 CCD25098.1 - 0.015 14.7 0.2 0.15 11.4 0.1 2.3 1 1 0 2 2 2 0 AAA domain DUF2172 PF09940.4 CCD25098.1 - 0.015 13.6 0.3 0.026 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) AAA_18 PF13238.1 CCD25098.1 - 0.073 13.3 0.1 0.073 13.3 0.0 4.2 2 2 1 3 3 3 0 AAA domain HI0933_like PF03486.9 CCD25098.1 - 2.4 6.5 8.7 9.4 4.5 4.9 2.1 2 0 0 2 2 2 0 HI0933-like protein UCH PF00443.24 CCD25099.1 - 4.5e-34 117.7 9.6 6.7e-34 117.2 6.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase R3H-assoc PF13902.1 CCD25099.1 - 0.081 12.8 0.9 0.24 11.3 0.1 2.1 2 0 0 2 2 2 0 R3H-associated N-terminal domain A2L_zn_ribbon PF08792.5 CCD25099.1 - 0.35 10.3 2.6 7.3 6.1 0.4 2.9 2 0 0 2 2 2 0 A2L zinc ribbon domain VPS9 PF02204.13 CCD25101.1 - 2.4e-18 66.0 3.0 1.1e-17 63.9 2.1 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain polyprenyl_synt PF00348.12 CCD25102.1 - 1.9e-46 158.0 0.0 2.2e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3605 PF12239.3 CCD25104.1 - 6.3e-35 120.3 7.3 4.7e-34 117.5 5.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) CorA PF01544.13 CCD25105.1 - 0.00012 21.2 10.0 0.00022 20.3 6.9 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Glutaredoxin PF00462.19 CCD25106.1 - 1.8e-18 66.2 0.0 3e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Aldedh PF00171.17 CCD25107.1 - 2.4e-172 573.4 0.2 2.6e-172 573.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NIF PF03031.13 CCD25108.1 - 2.2e-42 144.4 0.2 3.9e-42 143.6 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pro_isomerase PF00160.16 CCD25109.1 - 1.1e-05 25.7 0.0 2.7e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD VPS28 PF03997.7 CCD25110.1 - 6.3e-69 231.3 3.2 7.5e-69 231.1 2.2 1.1 1 0 0 1 1 1 1 VPS28 protein DUF1759 PF03564.10 CCD25110.1 - 0.15 11.9 5.4 0.39 10.5 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1759) Imm3 PF14425.1 CCD25110.1 - 0.25 11.3 2.9 0.45 10.5 0.1 2.3 2 1 0 2 2 2 0 Immunity protein Imm3 DUF4179 PF13786.1 CCD25111.1 - 0.017 15.3 0.1 0.017 15.3 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4179) ABC2_membrane PF01061.19 CCD25112.1 - 2.8e-67 225.9 47.3 2.3e-35 121.6 13.5 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 CCD25112.1 - 4.5e-36 124.1 0.0 1e-17 64.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCD25112.1 - 6.1e-35 119.0 2.6 2.7e-30 104.0 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CCD25112.1 - 3.9e-09 36.4 0.0 7.9e-09 35.4 0.0 1.5 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 CCD25112.1 - 3.4e-08 32.9 2.9 3.4e-08 32.9 2.0 2.9 2 1 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 CCD25112.1 - 9.2e-07 28.1 0.1 0.00019 20.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 CCD25112.1 - 1.4e-05 24.6 0.3 0.0013 18.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 CCD25112.1 - 6.2e-05 22.4 0.0 0.026 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCD25112.1 - 0.00012 21.5 0.4 0.015 14.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CCD25112.1 - 0.00031 19.9 0.1 0.63 9.0 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin SMC_N PF02463.14 CCD25112.1 - 0.00051 19.3 0.0 2.7 7.1 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCD25112.1 - 0.00061 20.5 0.0 0.021 15.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCD25112.1 - 0.00065 19.7 0.3 0.016 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCD25112.1 - 0.00067 19.8 1.1 0.037 14.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 CCD25112.1 - 0.0015 18.2 0.0 0.063 12.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 CCD25112.1 - 0.0027 17.6 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase UPF0079 PF02367.12 CCD25112.1 - 0.0034 17.0 2.1 0.019 14.5 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 CCD25112.1 - 0.0039 17.4 0.0 0.15 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCD25112.1 - 0.0052 16.9 0.0 1.7 8.8 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_21 PF13304.1 CCD25112.1 - 0.0086 16.0 0.2 0.13 12.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 CCD25112.1 - 0.016 14.9 0.8 0.19 11.4 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain NTPase_1 PF03266.10 CCD25112.1 - 0.017 14.8 0.2 13 5.4 0.1 3.2 3 0 0 3 3 3 0 NTPase AAA_33 PF13671.1 CCD25112.1 - 0.021 14.7 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 CCD25112.1 - 0.043 14.3 0.1 18 5.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 CCD25112.1 - 0.096 12.2 0.9 2.4 7.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CCD25112.1 - 0.12 11.7 1.9 4.1 6.7 0.2 2.7 3 0 0 3 3 2 0 AAA-like domain AAA PF00004.24 CCD25112.1 - 0.14 12.4 0.0 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CCD25112.1 - 0.2 11.1 1.2 1.2 8.5 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Gly_transf_sug PF04488.10 CCD25113.1 - 4.9e-22 78.2 0.7 1.5e-21 76.6 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CCD25113.1 - 0.023 13.1 3.0 0.53 8.7 0.5 2.4 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Lge1 PF11488.3 CCD25114.1 - 1.3e-09 38.0 3.4 1.3e-09 38.0 2.4 2.4 3 1 0 3 3 3 1 Transcriptional regulatory protein LGE1 CAP_N PF01213.14 CCD25114.1 - 0.0053 16.0 3.3 0.01 15.1 2.3 1.5 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 CCD25114.1 - 0.01 15.2 8.3 0.01 15.2 5.7 2.0 1 1 0 1 1 1 0 Mitochondrial fission regulator zf-CCCH PF00642.19 CCD25115.1 - 7.2e-09 35.1 12.2 4.3e-05 23.0 1.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CCD25115.1 - 0.42 10.6 24.5 0.69 10.0 4.2 3.0 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Glyco_transf_15 PF01793.11 CCD25116.1 - 5.4e-94 314.8 17.9 7.1e-94 314.4 12.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ODC_AZ PF02100.12 CCD25117.1 - 4.5e-05 22.9 0.0 0.00011 21.6 0.0 1.5 1 1 0 1 1 1 1 Ornithine decarboxylase antizyme PEGA PF08308.6 CCD25117.1 - 0.1 12.4 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 PEGA domain Arf PF00025.16 CCD25118.1 - 1.8e-46 157.5 0.2 2.2e-46 157.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCD25118.1 - 2.7e-15 56.1 0.0 3.6e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD25118.1 - 1.1e-13 51.6 0.0 2.1e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CCD25118.1 - 1.9e-12 46.8 0.9 7.6e-12 44.8 0.3 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CCD25118.1 - 4e-10 39.4 0.1 1.9e-09 37.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CCD25118.1 - 6.6e-10 38.2 2.3 1.5e-07 30.4 0.5 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCD25118.1 - 1.1e-07 31.2 0.3 1.2e-07 31.1 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCD25118.1 - 1.9e-06 27.7 0.1 3.1e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CCD25118.1 - 0.0018 18.4 0.1 0.01 16.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain Anp1 PF03452.9 CCD25119.1 - 1.2e-108 362.3 0.2 1.5e-108 362.0 0.1 1.1 1 0 0 1 1 1 1 Anp1 DUF4286 PF14114.1 CCD25119.1 - 0.00069 19.8 0.4 0.0023 18.1 0.3 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) Glycos_transf_2 PF00535.21 CCD25119.1 - 0.0072 16.0 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 SDA1 PF05285.7 CCD25119.1 - 0.022 14.0 1.1 0.034 13.4 0.8 1.3 1 0 0 1 1 1 0 SDA1 EF1G PF00647.14 CCD25120.1 - 1.3e-47 159.8 0.1 2.7e-47 158.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CCD25120.1 - 4.8e-13 48.8 0.0 1.5e-12 47.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCD25120.1 - 1.2e-10 41.3 0.0 3.3e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCD25120.1 - 1.2e-05 25.0 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCD25120.1 - 9.2e-05 22.5 0.0 0.00028 21.0 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Sgf11 PF08209.6 CCD25121.1 - 1.8e-17 62.2 4.4 3.2e-17 61.5 3.0 1.4 2 0 0 2 2 2 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 CCD25121.1 - 0.029 14.0 1.8 0.045 13.4 0.6 1.8 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF1451 PF07295.6 CCD25121.1 - 0.029 14.1 0.2 0.31 10.8 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) Skp1_POZ PF03931.10 CCD25122.1 - 1.2e-09 38.0 0.0 1.9e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Vps16_C PF04840.7 CCD25123.1 - 7e-76 255.1 12.0 2e-75 253.6 7.4 2.1 2 0 0 2 2 2 1 Vps16, C-terminal region Vps16_N PF04841.8 CCD25123.1 - 3.9e-58 196.9 0.5 4.8e-47 160.3 0.0 2.3 2 0 0 2 2 2 2 Vps16, N-terminal region RRM_1 PF00076.17 CCD25124.1 - 1.2e-54 181.7 0.1 2.8e-17 62.0 0.1 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD25124.1 - 4.1e-41 138.7 0.2 4.5e-12 45.7 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD25124.1 - 5.5e-15 54.9 0.3 8.7e-07 28.7 0.0 5.0 5 0 0 5 5 5 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CCD25125.1 - 3.9e-53 180.2 3.5 1.4e-51 175.1 0.1 2.5 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25125.1 - 2.3e-25 89.1 3.6 6.9e-25 87.5 0.1 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase FLILHELTA PF10306.4 CCD25126.1 - 2.1e-22 78.9 0.0 3.7e-22 78.1 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA tRNA-synt_1 PF00133.17 CCD25127.1 - 5.3e-164 546.5 0.2 7.2e-164 546.0 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CCD25127.1 - 2e-25 89.2 0.1 1.8e-12 46.6 0.0 3.7 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CCD25127.1 - 6.1e-21 74.7 0.8 6.1e-21 74.7 0.6 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1_2 PF13603.1 CCD25127.1 - 0.0032 16.7 0.1 0.028 13.7 0.0 2.3 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.9 CCD25127.1 - 0.012 15.2 2.9 0.026 14.1 2.0 1.6 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-C2H2_4 PF13894.1 CCD25129.1 - 7.5e-10 38.4 2.9 0.0009 19.4 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCD25129.1 - 1.4e-07 31.3 7.0 0.0019 18.4 0.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCD25129.1 - 0.068 13.3 0.5 0.44 10.7 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CCD25129.1 - 0.14 12.4 7.6 13 6.2 0.1 3.8 3 1 0 3 3 3 0 Zinc-finger double domain Ndc1_Nup PF09531.5 CCD25129.1 - 0.17 10.2 7.1 0.19 10.0 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup C1_4 PF07975.7 CCD25129.1 - 0.34 10.9 1.6 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 TFIIH C1-like domain RIG-I_C-RD PF11648.3 CCD25129.1 - 0.54 10.1 3.1 0.25 11.1 0.4 1.7 2 0 0 2 2 2 0 C-terminal domain of RIG-I PSCyt3 PF07627.6 CCD25129.1 - 3.7 7.4 5.9 0.37 10.6 0.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) zf-H2C2_5 PF13909.1 CCD25129.1 - 4.4 7.7 5.3 3.9 7.9 0.3 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain Macoilin PF09726.4 CCD25129.1 - 4.6 5.4 11.8 4.9 5.2 8.2 1.1 1 0 0 1 1 1 0 Transmembrane protein NAC PF01849.13 CCD25130.1 - 7.8e-16 57.3 0.1 1.7e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 NAC domain DUF3886 PF13025.1 CCD25130.1 - 0.63 10.0 5.1 0.12 12.3 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) zf-CCHC PF00098.18 CCD25131.1 - 9.2e-05 22.1 1.6 0.00016 21.3 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle Peptidase_M9 PF01752.12 CCD25131.1 - 0.0061 15.5 0.3 0.0091 14.9 0.2 1.2 1 0 0 1 1 1 1 Collagenase zf-CCHC_4 PF14392.1 CCD25131.1 - 0.017 14.7 1.1 0.048 13.3 0.8 1.8 1 0 0 1 1 1 0 Zinc knuckle ApbA_C PF08546.6 CCD25133.1 - 7.6e-08 32.3 0.0 1.6e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal DUF2762 PF10960.3 CCD25133.1 - 8.1 6.2 20.5 0.5 10.1 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) Pkinase PF00069.20 CCD25134.1 - 3.1e-76 255.9 0.0 3.8e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25134.1 - 3.7e-38 131.0 0.0 5.4e-38 130.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD25134.1 - 2.7e-05 23.2 0.0 4.6e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCD25134.1 - 0.049 13.3 0.0 0.27 10.9 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCD25134.1 - 0.084 11.6 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 AdoMet_MTase PF07757.8 CCD25135.1 - 7.9e-39 132.2 1.3 1e-37 128.6 0.9 2.3 1 1 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.1 CCD25135.1 - 0.0016 18.0 0.3 0.0049 16.4 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCD25135.1 - 0.086 12.5 0.2 7 6.3 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 CCD25135.1 - 0.14 12.7 0.0 0.54 10.8 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain PRANC PF09372.5 CCD25135.1 - 1.3 9.0 7.8 0.21 11.6 0.5 3.0 3 0 0 3 3 3 0 PRANC domain SUV3_C PF12513.3 CCD25136.1 - 1.3e-16 59.7 1.5 3.2e-16 58.4 1.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CCD25136.1 - 5.7e-13 48.5 0.0 2.6e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain RNA_pol_A_bac PF01000.21 CCD25136.1 - 0.057 13.5 0.4 0.5 10.5 0.1 2.6 2 1 0 2 2 2 0 RNA polymerase Rpb3/RpoA insert domain Thiolase_N PF00108.18 CCD25137.1 - 1.4e-99 332.4 2.1 1.7e-99 332.0 1.5 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCD25137.1 - 1.7e-46 156.6 2.7 1.9e-46 156.4 0.1 2.4 3 1 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCD25137.1 - 2.1e-06 27.4 0.9 4e-06 26.4 0.6 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Pkinase PF00069.20 CCD25138.1 - 1.6e-51 174.9 2.5 5.9e-50 169.8 1.8 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25138.1 - 1e-23 83.7 0.2 1.8e-19 69.8 0.0 2.3 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCD25138.1 - 2.3e-05 23.5 0.1 0.00019 20.5 0.1 2.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCD25138.1 - 0.14 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1767 PF08585.7 CCD25139.1 - 0.017 15.3 0.3 0.68 10.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1767) Spo7_2_N PF15407.1 CCD25139.1 - 0.086 12.3 0.0 0.26 10.7 0.0 1.8 1 0 0 1 1 1 0 Sporulation protein family 7 Hep_59 PF07052.6 CCD25139.1 - 2.3 8.6 7.6 0.53 10.6 0.9 2.3 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 MTHFR PF02219.12 CCD25140.1 - 1.9e-108 361.8 0.0 2.5e-108 361.5 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ERCC4 PF02732.10 CCD25141.1 - 9.8e-25 86.9 0.0 2.9e-24 85.4 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain HHH_2 PF12826.2 CCD25141.1 - 0.063 13.1 0.2 5.2 7.0 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix motif ARID PF01388.16 CCD25142.1 - 1.2e-22 79.5 0.5 1.2e-22 79.5 0.4 3.6 4 0 0 4 4 4 1 ARID/BRIGHT DNA binding domain RRM_1 PF00076.17 CCD25143.1 - 5.8e-05 22.6 0.1 0.00016 21.2 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD25143.1 - 0.021 14.6 0.1 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GLE1 PF07817.8 CCD25144.1 - 5e-88 294.3 0.7 5e-88 294.3 0.5 2.7 3 0 0 3 3 3 1 GLE1-like protein Na_Ca_ex PF01699.19 CCD25145.1 - 1.6e-48 163.9 24.6 2.7e-26 91.8 7.3 4.0 2 2 1 3 3 3 2 Sodium/calcium exchanger protein SPC25 PF06703.6 CCD25145.1 - 0.013 15.1 0.5 0.19 11.3 0.2 2.6 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Porphobil_deam PF01379.15 CCD25146.1 - 3.4e-85 284.3 0.0 4.3e-85 284.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CCD25146.1 - 4.4e-19 68.3 0.2 8.1e-19 67.5 0.1 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Reticulon PF02453.12 CCD25147.1 - 5.8e-22 78.0 11.2 1.9e-21 76.4 7.8 1.7 1 1 0 1 1 1 1 Reticulon DUF639 PF04842.7 CCD25147.1 - 0.0042 15.3 4.4 0.0054 14.9 3.1 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF639) DUF1507 PF07408.6 CCD25147.1 - 0.059 13.1 0.0 0.3 10.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1507) DUF2721 PF11026.3 CCD25147.1 - 0.73 9.4 3.9 1.6 8.3 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2721) Sel1 PF08238.7 CCD25148.1 - 1e-23 83.2 10.4 0.00032 21.2 0.0 7.4 7 1 0 7 7 7 6 Sel1 repeat Ribosomal_L10 PF00466.15 CCD25149.1 - 1e-07 31.7 0.0 2.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Methyltransf_4 PF02390.12 CCD25150.1 - 1.9e-58 196.7 0.1 1.9e-58 196.7 0.1 1.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCD25150.1 - 0.00013 22.5 0.0 0.00022 21.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCD25150.1 - 0.00019 21.0 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCD25150.1 - 0.0019 18.6 0.0 0.006 17.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCD25150.1 - 0.0075 16.2 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD25150.1 - 0.0081 16.5 0.0 0.025 14.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DUF3958 PF13125.1 CCD25150.1 - 0.029 14.2 1.3 0.05 13.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) DUF844 PF05815.6 CCD25150.1 - 0.043 12.6 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) DUF2431 PF10354.4 CCD25150.1 - 0.061 13.2 0.2 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) Ubie_methyltran PF01209.13 CCD25150.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DNA_binding_1 PF01035.15 CCD25151.1 - 4.7e-28 96.7 0.0 7e-28 96.1 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.10 CCD25151.1 - 0.035 14.7 0.1 0.054 14.0 0.1 1.3 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain DUF2957 PF11170.3 CCD25152.1 - 0.023 13.3 7.8 0.25 9.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2957) PAP1 PF08601.5 CCD25152.1 - 7.8 6.0 10.2 9.9 5.7 7.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 LSM PF01423.17 CCD25153.1 - 7.3e-16 57.4 0.1 8.4e-16 57.2 0.1 1.1 1 0 0 1 1 1 1 LSM domain Rhabdo_ncap PF00945.13 CCD25153.1 - 0.074 11.6 0.1 0.089 11.3 0.1 1.0 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein BPL_C PF02237.12 CCD25153.1 - 0.11 12.2 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Cohesin_load PF10345.4 CCD25154.1 - 6.5e-90 302.0 37.0 8.1e-90 301.7 25.6 1.0 1 0 0 1 1 1 1 Cohesin loading factor TBP PF00352.16 CCD25155.1 - 9.9e-70 229.9 0.1 4.9e-35 118.7 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CCD25155.1 - 0.0016 18.4 4.5 0.71 9.9 0.0 3.2 3 1 1 4 4 4 2 Domain of unknown function (DUF3378) Mito_carr PF00153.22 CCD25156.1 - 4e-31 106.5 0.2 1.4e-14 53.5 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Rsa3 PF14615.1 CCD25160.1 - 6.6e-20 70.1 0.3 1.2e-19 69.2 0.2 1.5 1 0 0 1 1 1 1 Ribosome-assembly protein 3 Phe_tRNA-synt_N PF02912.13 CCD25160.1 - 0.041 13.6 0.5 0.29 10.8 0.4 2.5 2 1 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain SR-25 PF10500.4 CCD25160.1 - 0.069 12.6 16.0 0.099 12.0 11.1 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1664 PF07889.7 CCD25160.1 - 0.077 12.7 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Fmp27_SW PF10305.4 CCD25160.1 - 0.23 11.9 3.7 2.1 8.8 0.3 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Utp14 PF04615.8 CCD25160.1 - 0.29 9.2 15.4 0.33 9.0 10.7 1.0 1 0 0 1 1 1 0 Utp14 protein CAML PF14963.1 CCD25160.1 - 1.4 8.2 13.0 1.8 7.8 9.0 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF755 PF05501.6 CCD25160.1 - 5.6 7.0 16.5 14 5.7 11.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) WD40 PF00400.27 CCD25161.1 - 2.6e-63 207.8 28.3 6.2e-10 38.5 0.2 11.4 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.6 CCD25161.1 - 3.9e-48 162.6 1.9 7.5e-48 161.7 1.3 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 CCD25161.1 - 0.033 12.3 16.5 0.85 7.6 0.1 5.5 4 1 1 6 6 6 0 Nucleoporin Nup120/160 PIP5K PF01504.13 CCD25162.1 - 1.2e-74 250.6 5.7 2.3e-74 249.7 3.9 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Di19_C PF14571.1 CCD25162.1 - 0.051 13.9 18.5 0.82 10.0 6.1 2.9 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal SR-25 PF10500.4 CCD25162.1 - 1.2 8.5 23.5 0.013 14.9 10.3 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Zn_clus PF00172.13 CCD25163.1 - 2e-09 37.1 12.2 3.2e-09 36.5 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRF1 PF10380.4 CCD25166.1 - 2.9e-36 124.5 5.7 2.9e-36 124.5 3.9 5.5 3 2 0 3 3 3 1 Transcription factor CRF1 Lum_binding PF00677.12 CCD25167.1 - 1.5e-43 146.5 9.5 1.9e-22 78.9 0.5 2.3 2 0 0 2 2 2 2 Lumazine binding domain Cut8_C PF08559.5 CCD25168.1 - 2.4e-37 127.9 4.2 6e-37 126.6 2.9 1.7 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 CCD25168.1 - 0.0044 16.7 0.7 0.0092 15.7 0.5 1.5 1 0 0 1 1 1 1 Cut8 dimerisation domain WASH_WAHD PF11945.3 CCD25169.1 - 0.084 12.1 0.0 0.084 12.1 0.0 1.1 1 0 0 1 1 1 0 WAHD domain of WASH complex Sedlin_N PF04628.8 CCD25171.1 - 2.9e-44 150.1 0.0 5.2e-44 149.3 0.0 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CCD25171.1 - 3.7e-05 23.4 0.5 0.005 16.5 0.1 2.5 3 0 0 3 3 3 2 Sybindin-like family Med22 PF06179.7 CCD25172.1 - 5.9e-19 68.1 2.1 7.4e-19 67.7 1.4 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex PET PF06297.9 CCD25172.1 - 0.098 12.3 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 PET Domain Ribosomal_S5 PF00333.15 CCD25173.1 - 1.4e-22 79.2 0.1 2.3e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CCD25173.1 - 5.9e-19 67.1 0.0 1.3e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain HMG_box PF00505.14 CCD25174.1 - 1.2e-13 51.1 12.6 3.3e-13 49.6 7.1 2.6 2 1 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCD25174.1 - 0.00063 20.0 5.0 0.0018 18.6 3.5 1.7 1 1 0 1 1 1 1 HMG-box domain Peptidase_M41 PF01434.13 CCD25175.1 - 3.8e-77 258.5 0.2 7.5e-77 257.5 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CCD25175.1 - 5.8e-44 149.5 0.0 1.6e-43 148.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CCD25175.1 - 3.1e-06 27.3 0.3 3.1e-06 27.3 0.2 2.2 2 0 0 2 2 2 1 FtsH Extracellular AAA_5 PF07728.9 CCD25175.1 - 0.00013 21.7 0.0 0.00068 19.3 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CCD25175.1 - 0.00019 22.2 0.0 0.00092 20.0 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCD25175.1 - 0.0023 18.0 0.9 0.18 11.9 0.1 2.8 2 1 0 3 3 2 1 AAA domain TIP49 PF06068.8 CCD25175.1 - 0.0027 16.5 0.5 0.0061 15.3 0.0 1.8 2 0 0 2 2 2 1 TIP49 C-terminus RuvB_N PF05496.7 CCD25175.1 - 0.0047 16.0 0.0 0.01 14.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CCD25175.1 - 0.0048 16.3 0.1 0.016 14.6 0.0 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CCD25175.1 - 0.0052 16.5 0.9 0.014 15.0 0.6 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 CCD25175.1 - 0.01 16.1 2.1 0.25 11.6 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 CCD25175.1 - 0.015 15.2 0.2 0.061 13.3 0.1 2.1 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 CCD25175.1 - 0.02 13.9 0.6 0.057 12.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_2 PF07724.9 CCD25175.1 - 0.04 13.8 2.6 0.12 12.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain (Cdc48 subfamily) DUF2370 PF10176.4 CCD25175.1 - 0.066 12.5 0.2 0.13 11.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) AAA_33 PF13671.1 CCD25175.1 - 0.074 12.9 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCD25175.1 - 0.079 12.3 2.3 0.13 11.6 0.4 2.2 2 1 0 2 2 2 0 AAA domain EB1 PF03271.12 CCD25176.1 - 4.7e-18 64.9 0.8 1.3e-17 63.5 0.6 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 CCD25176.1 - 1.9e-05 24.6 0.7 3.8e-05 23.6 0.5 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain DivIC PF04977.10 CCD25176.1 - 0.046 13.2 0.5 0.11 12.0 0.3 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF4349 PF14257.1 CCD25176.1 - 0.55 9.4 5.2 1.8 7.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) AMP-binding PF00501.23 CCD25177.1 - 1.4e-68 231.1 0.0 1.9e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_8 PF13450.1 CCD25178.1 - 9.2e-10 38.4 0.0 2.4e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCD25178.1 - 0.00015 22.0 1.2 0.011 16.1 0.1 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 CCD25178.1 - 0.0007 18.7 0.0 0.00076 18.6 0.0 1.3 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 CCD25178.1 - 0.00071 18.5 0.1 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 CCD25178.1 - 0.017 14.2 0.1 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 CCD25178.1 - 0.018 15.0 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCD25178.1 - 0.026 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding OB_NTP_bind PF07717.11 CCD25179.1 - 8.9e-27 93.1 0.0 2.5e-26 91.7 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CCD25179.1 - 3.3e-26 91.2 0.1 8.5e-26 89.9 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) S1 PF00575.18 CCD25179.1 - 7.9e-15 54.7 0.2 1.9e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Helicase_C PF00271.26 CCD25179.1 - 9.8e-13 47.7 0.0 3.7e-12 45.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD25179.1 - 4.8e-07 29.4 0.1 1.1e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCD25179.1 - 1.5e-06 28.3 0.1 4.4e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCD25179.1 - 0.00027 19.9 0.0 0.0015 17.4 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.1 CCD25179.1 - 0.00052 19.6 0.1 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCD25179.1 - 0.0007 19.9 6.0 0.19 11.9 0.1 3.8 2 2 1 3 3 3 2 ABC transporter Sigma54_activ_2 PF14532.1 CCD25179.1 - 0.0011 19.0 0.0 0.0091 16.0 0.0 2.4 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_14 PF13173.1 CCD25179.1 - 0.0018 18.1 0.2 0.022 14.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 CCD25179.1 - 0.006 15.4 0.1 0.014 14.3 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain SRP54 PF00448.17 CCD25179.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ResIII PF04851.10 CCD25179.1 - 0.017 14.9 0.0 2.6 7.8 0.0 2.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCD25179.1 - 0.081 12.6 0.1 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 CCD25179.1 - 0.13 12.5 4.4 0.76 10.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain Proteasome PF00227.21 CCD25180.1 - 5e-44 149.8 0.0 5.9e-44 149.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit NAD_binding_10 PF13460.1 CCD25181.1 - 7.7e-11 42.3 0.0 1e-10 41.9 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 CCD25181.1 - 1.5e-07 30.2 0.0 4.5e-06 25.3 0.0 2.2 1 1 0 1 1 1 1 HIM1 NAD_binding_4 PF07993.7 CCD25181.1 - 0.00045 19.2 0.0 0.062 12.2 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.8 CCD25181.1 - 0.00056 19.2 0.1 0.0035 16.6 0.0 2.1 2 1 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 CCD25181.1 - 0.0026 17.2 0.0 0.0059 16.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CCD25181.1 - 0.076 13.3 0.0 0.25 11.6 0.0 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain SRP1_TIP1 PF00660.12 CCD25182.1 - 8.8e-25 86.5 0.6 3.5e-24 84.5 0.4 2.0 1 0 0 1 1 1 1 Seripauperin and TIP1 family DctQ PF04290.7 CCD25182.1 - 0.059 13.1 0.3 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component WSC PF01822.14 CCD25183.1 - 2.2e-12 46.7 16.8 2.2e-12 46.7 11.6 2.5 2 1 0 2 2 2 1 WSC domain Gly-zipper_Omp PF13488.1 CCD25183.1 - 0.0017 17.9 1.8 0.0035 16.9 1.2 1.4 1 0 0 1 1 1 1 Glycine zipper ApbA_C PF08546.6 CCD25183.1 - 0.022 14.7 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Prim_Zn_Ribbon PF08273.7 CCD25183.1 - 0.028 14.5 1.5 0.047 13.7 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF1275 PF06912.6 CCD25183.1 - 0.072 12.2 1.9 0.14 11.3 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) Beta-APP PF03494.8 CCD25183.1 - 3.7 7.0 6.4 8.7 5.9 4.4 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) RTBV_P12 PF06361.6 CCD25183.1 - 7.4 6.8 8.6 2.4 8.4 1.3 2.6 2 0 0 2 2 2 0 Rice tungro bacilliform virus P12 protein DUF2408 PF10303.4 CCD25184.1 - 5.5e-69 230.4 22.7 2.2e-45 154.0 2.8 5.0 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) MtrG PF04210.8 CCD25184.1 - 0.077 12.6 0.3 25 4.6 0.0 3.2 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G PilJ PF13675.1 CCD25184.1 - 0.13 12.6 2.6 13 6.0 0.1 3.7 2 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term THP2 PF09432.5 CCD25184.1 - 8.6 6.2 11.9 0.76 9.6 1.1 3.2 3 1 0 4 4 4 0 Tho complex subunit THP2 Adap_comp_sub PF00928.16 CCD25185.1 - 6.1e-90 300.8 2.9 7.9e-90 300.4 2.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.4 CCD25185.1 - 6.3e-05 22.2 0.1 9.9e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain Clat_adaptor_s PF01217.15 CCD25185.1 - 0.00021 21.0 0.8 0.00039 20.1 0.6 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TPP1 PF10341.4 CCD25186.1 - 4.4e-29 100.5 0.1 6.1e-29 100.1 0.1 1.2 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD ETF_QO PF05187.8 CCD25187.1 - 1.7e-37 127.7 0.1 2.8e-37 127.0 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CCD25187.1 - 4.5e-11 42.2 0.0 1.3e-05 24.2 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCD25187.1 - 4.8e-08 32.9 0.0 1.2e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCD25187.1 - 5.7e-08 32.1 0.0 2.5e-05 23.4 0.0 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_2 PF00890.19 CCD25187.1 - 1.5e-07 30.6 0.1 0.00096 18.1 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 CCD25187.1 - 9.8e-05 20.9 0.0 0.00057 18.4 0.0 2.0 1 1 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 CCD25187.1 - 0.00022 20.4 0.0 0.00042 19.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCD25187.1 - 0.00027 21.2 0.1 0.19 12.1 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCD25187.1 - 0.00047 20.2 0.0 0.0016 18.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 CCD25187.1 - 0.00086 18.4 0.1 0.0014 17.7 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 CCD25187.1 - 0.00088 19.0 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCD25187.1 - 0.001 18.9 0.0 0.0027 17.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CCD25187.1 - 0.0022 16.7 0.2 0.021 13.4 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GMC_oxred_N PF00732.14 CCD25187.1 - 0.0041 16.3 0.0 0.32 10.1 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase Fer4_7 PF12838.2 CCD25187.1 - 0.0074 16.6 0.6 0.019 15.3 0.4 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 CCD25187.1 - 0.022 13.6 0.0 0.033 13.1 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_10 PF13237.1 CCD25187.1 - 0.057 13.2 0.5 0.12 12.1 0.4 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 CCD25187.1 - 0.068 13.1 0.7 0.18 11.7 0.5 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain Cyclin_N PF00134.18 CCD25189.1 - 1.6e-28 98.8 2.6 4.7e-28 97.3 1.8 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain PPR_3 PF13812.1 CCD25190.1 - 0.0045 17.1 0.0 2.9 8.4 0.0 4.3 4 0 0 4 4 4 1 Pentatricopeptide repeat domain Sigma70_r1_1 PF03979.9 CCD25190.1 - 0.079 12.8 0.4 0.3 11.0 0.3 2.1 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 SOG2 PF10428.4 CCD25191.1 - 8.3e-108 360.8 44.0 8.3e-108 360.8 30.5 4.1 3 1 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 CCD25191.1 - 2.9e-16 58.6 18.3 6.5e-09 35.2 1.1 4.3 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCD25191.1 - 9.7e-14 50.8 13.5 6e-11 41.9 1.8 3.0 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 CCD25191.1 - 8.3e-09 34.2 12.4 0.059 13.4 0.4 6.2 6 0 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 CCD25191.1 - 3.7e-05 23.2 8.1 0.3 11.4 0.1 5.5 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 CCD25191.1 - 0.039 14.0 13.2 10 6.5 0.1 6.6 7 1 1 8 8 8 0 Leucine Rich repeat Pkinase PF00069.20 CCD25193.1 - 1e-62 211.6 1.1 2.2e-62 210.5 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25193.1 - 1.2e-28 99.9 0.0 2.4e-27 95.6 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CCD25193.1 - 8.3e-16 57.8 0.0 2.8e-15 56.1 0.0 2.0 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 CCD25193.1 - 0.00012 21.1 0.0 0.33 9.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CCD25193.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPA_interact_C PF14768.1 CCD25194.1 - 0.61 10.5 0.0 0.61 10.5 0.0 4.0 2 2 1 4 4 4 0 Replication protein A interacting C-terminal MNE1 PF13762.1 CCD25195.1 - 5.1e-13 49.3 5.9 5.1e-13 49.3 4.1 3.8 3 1 0 3 3 3 1 Mitochondrial splicing apparatus component DNA_Packaging_2 PF11123.3 CCD25195.1 - 0.014 15.2 0.6 0.11 12.3 0.1 2.5 2 0 0 2 2 2 0 DNA packaging protein Mistic PF11458.3 CCD25196.1 - 0.013 15.8 1.0 0.049 14.0 0.1 2.4 2 0 0 2 2 2 0 Membrane-integrating protein Mistic UPF0149 PF03695.8 CCD25196.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0149) Apc5 PF12862.2 CCD25196.1 - 0.15 11.9 6.7 3.2 7.6 0.1 3.2 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 AA_permease PF00324.16 CCD25197.1 - 2.2e-128 428.5 38.1 2.6e-128 428.3 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD25197.1 - 3.6e-20 71.9 43.5 4.7e-20 71.5 30.1 1.1 1 0 0 1 1 1 1 Amino acid permease DNA_pol_A PF00476.15 CCD25198.1 - 1.5e-107 359.5 0.0 2.3e-107 358.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A CorA PF01544.13 CCD25199.1 - 1.8e-06 27.2 6.7 3.5e-06 26.2 4.7 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein 7tm_3 PF00003.17 CCD25199.1 - 0.042 13.1 0.4 0.066 12.5 0.2 1.2 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR tRNA-synt_2c PF01411.14 CCD25200.1 - 2.1e-226 752.5 0.5 3.4e-226 751.8 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CCD25200.1 - 2.8e-18 65.4 0.1 7.7e-18 64.1 0.1 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CCD25200.1 - 2e-06 27.3 2.1 4.9e-06 26.1 1.5 1.7 1 0 0 1 1 1 1 DHHA1 domain UDP-g_GGTase PF06427.6 CCD25201.1 - 4.7e-10 39.1 0.1 1.2e-09 37.7 0.1 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase DUF2507 PF10702.4 CCD25201.1 - 0.027 14.1 0.5 0.2 11.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2507) Fungal_trans PF04082.13 CCD25202.1 - 4e-34 117.6 4.3 4e-34 117.6 3.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD25202.1 - 2.9e-07 30.2 11.4 5.1e-07 29.4 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIRM PF04433.12 CCD25203.1 - 6e-13 48.7 0.0 1.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Pol_alpha_B_N PF08418.5 CCD25203.1 - 0.22 11.0 14.4 0.027 13.9 0.9 2.2 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal UQ_con PF00179.21 CCD25204.1 - 1.4e-48 163.8 0.1 1.6e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCD25204.1 - 0.0012 18.5 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCD25204.1 - 0.0019 18.0 0.1 0.0029 17.4 0.0 1.6 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 CCD25204.1 - 0.01 15.5 0.4 0.018 14.7 0.3 1.4 1 1 0 1 1 1 0 UEV domain SHS2_Rpb7-N PF03876.12 CCD25205.1 - 3.2e-12 46.3 0.0 8.9e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GTP_EFTU PF00009.22 CCD25206.1 - 7.1e-33 113.6 0.0 7.1e-33 113.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CCD25206.1 - 1.6e-20 72.9 0.0 4.9e-20 71.4 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CCD25206.1 - 1.6e-15 56.9 0.7 1.2e-09 38.1 0.0 3.4 2 0 0 2 2 2 2 Elongation factor Tu domain 2 AAA_22 PF13401.1 CCD25206.1 - 1.2 9.3 5.6 0.29 11.2 0.1 2.8 2 1 0 2 2 2 0 AAA domain Pyrophosphatase PF00719.14 CCD25207.1 - 5.4e-51 172.1 0.3 7.2e-51 171.7 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Acetate_kinase PF00871.12 CCD25208.1 - 0.0064 15.0 0.0 0.0079 14.7 0.0 1.2 1 0 0 1 1 1 1 Acetokinase family HLH PF00010.21 CCD25209.1 - 8.5e-22 76.6 0.2 2.6e-21 75.0 0.2 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Prenyltrans_2 PF13249.1 CCD25209.1 - 0.45 10.9 4.6 11 6.4 3.2 2.3 1 1 0 1 1 1 0 Prenyltransferase-like IlvC PF01450.14 CCD25209.1 - 5.8 6.8 8.5 1.7 8.5 0.1 2.9 2 1 1 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain IMS PF00817.15 CCD25210.1 - 1.2e-24 86.8 0.0 1.1e-23 83.6 0.0 2.4 1 1 0 1 1 1 1 impB/mucB/samB family BRCT PF00533.21 CCD25210.1 - 8.3e-11 41.8 0.5 3.8e-10 39.7 0.3 2.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_C PF11799.3 CCD25210.1 - 2.1e-09 37.3 0.0 8.7e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain PTCB-BRCT PF12738.2 CCD25210.1 - 2.6e-06 27.2 0.1 5.9e-06 26.0 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain IMS_HHH PF11798.3 CCD25210.1 - 0.0005 19.9 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif DUF4414 PF14377.1 CCD25210.1 - 0.035 14.0 8.6 0.32 10.9 0.8 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4414) PK PF00224.16 CCD25211.1 - 4.7e-162 538.4 2.6 6.1e-162 538.1 1.8 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CCD25211.1 - 2.6e-29 101.1 0.0 5.8e-29 100.0 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CCD25211.1 - 0.00039 19.3 0.2 0.00077 18.4 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family ATP-synt_ab PF00006.20 CCD25212.1 - 6.2e-70 235.0 0.0 8.7e-70 234.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCD25212.1 - 2.2e-25 89.2 0.3 6.8e-25 87.7 0.2 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCD25212.1 - 9.4e-17 60.9 1.5 2.7e-16 59.5 1.0 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Tex_N PF09371.5 CCD25212.1 - 0.0032 16.8 0.0 0.0079 15.5 0.0 1.6 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HAS-barrel PF09378.5 CCD25212.1 - 0.0085 15.9 0.6 0.02 14.7 0.4 1.7 1 0 0 1 1 1 1 HAS barrel domain AAA_25 PF13481.1 CCD25212.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Peptidase_M41 PF01434.13 CCD25213.1 - 1.8e-71 240.0 0.5 3e-71 239.2 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CCD25213.1 - 5.1e-44 149.6 0.1 1.4e-43 148.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCD25213.1 - 8.4e-06 25.9 0.2 0.00085 19.4 0.2 3.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCD25213.1 - 1.7e-05 24.6 0.0 8.2e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCD25213.1 - 4.1e-05 23.5 0.0 0.00014 21.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 CCD25213.1 - 7.4e-05 23.5 0.5 0.00065 20.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.7 CCD25213.1 - 0.00015 20.9 0.0 0.00038 19.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCD25213.1 - 0.00015 21.6 0.0 0.00046 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCD25213.1 - 0.00024 21.1 0.0 0.00071 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.8 CCD25213.1 - 0.00026 19.8 0.0 0.00057 18.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 CCD25213.1 - 0.00089 18.9 1.1 0.0026 17.4 0.8 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 CCD25213.1 - 0.0014 18.1 1.4 0.047 13.0 0.3 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCD25213.1 - 0.0044 16.4 0.2 0.012 15.0 0.1 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CCD25213.1 - 0.0074 16.5 0.3 0.026 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CCD25213.1 - 0.013 14.5 0.2 0.13 11.3 0.1 2.2 1 1 0 2 2 2 0 KaiC NTPase_1 PF03266.10 CCD25213.1 - 0.03 14.0 1.5 0.44 10.2 0.1 2.9 2 1 1 3 3 3 0 NTPase Mg_chelatase PF01078.16 CCD25213.1 - 0.034 13.3 0.4 0.072 12.2 0.3 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CCD25213.1 - 0.04 13.8 0.3 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CCD25213.1 - 0.067 13.0 0.0 0.19 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 CCD25213.1 - 0.069 12.3 0.3 0.18 11.0 0.2 1.6 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 CCD25213.1 - 0.077 13.0 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Cnd2 PF05786.9 CCD25214.1 - 5.8e-122 408.6 55.8 6.2e-78 263.0 25.6 2.7 2 1 0 2 2 2 2 Condensin complex subunit 2 Rad21_Rec8_N PF04825.8 CCD25214.1 - 0.061 13.2 0.0 0.26 11.2 0.0 2.1 2 0 0 2 2 2 0 N terminus of Rad21 / Rec8 like protein 4HBT PF03061.17 CCD25215.1 - 2.7e-05 24.1 0.0 4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Rox3 PF08633.5 CCD25216.1 - 4.9e-59 199.8 3.8 5.7e-59 199.6 2.7 1.0 1 0 0 1 1 1 1 Rox3 mediator complex subunit Ribosomal_L32e PF01655.13 CCD25217.1 - 3.1e-46 155.9 1.8 3.6e-46 155.7 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF3437 PF11919.3 CCD25217.1 - 0.21 11.2 0.9 0.29 10.8 0.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Aa_trans PF01490.13 CCD25218.1 - 6.8e-109 364.0 24.5 7.7e-109 363.8 17.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_9_N PF15420.1 CCD25218.1 - 0.0016 18.2 0.8 0.13 12.0 0.0 2.6 2 1 1 3 3 3 2 Alpha/beta-hydrolase family N-terminus SHR3_chaperone PF08229.6 CCD25218.1 - 2.2 7.1 5.8 0.21 10.5 0.3 2.1 2 1 0 2 2 2 0 ER membrane protein SH3 PI3_PI4_kinase PF00454.22 CCD25219.1 - 1.1e-50 172.3 0.0 3.5e-50 170.6 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 CCD25219.1 - 9.9e-23 80.5 4.2 9.9e-23 80.5 2.9 2.7 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 CCD25219.1 - 4.3e-13 48.4 0.1 1e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 FATC domain SpoIIID PF12116.3 CCD25219.1 - 0.1 12.5 0.1 0.3 11.0 0.1 1.7 1 0 0 1 1 1 0 Stage III sporulation protein D Ribosomal_L14 PF00238.14 CCD25220.1 - 5.1e-32 110.1 0.0 5.7e-32 110.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e TPR_1 PF00515.23 CCD25221.1 - 2.4e-34 115.5 5.3 4.1e-08 32.4 0.0 8.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 CCD25221.1 - 1.7e-32 108.7 3.2 2.8e-06 26.8 0.0 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_11 PF13414.1 CCD25221.1 - 1.4e-31 107.9 11.4 8.4e-10 38.1 0.3 6.9 3 1 4 7 7 7 5 TPR repeat TPR_8 PF13181.1 CCD25221.1 - 1.3e-26 90.3 4.3 9.1e-05 21.9 0.1 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 CCD25221.1 - 5.1e-24 84.2 28.1 3.3e-16 59.1 3.3 4.7 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CCD25221.1 - 3.7e-20 72.0 0.0 7.6e-08 32.8 0.0 4.9 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCD25221.1 - 2.5e-16 59.3 1.6 0.0003 20.6 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCD25221.1 - 1.1e-10 41.1 0.0 0.25 12.0 0.0 6.5 3 2 4 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCD25221.1 - 3.4e-10 38.9 0.0 0.47 10.3 0.0 6.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCD25221.1 - 5.1e-10 39.1 5.4 1.2 9.7 0.0 7.1 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCD25221.1 - 2.4e-08 34.1 0.0 0.034 14.4 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCD25221.1 - 5.3e-08 32.4 7.3 0.6 10.4 0.0 7.6 7 1 2 9 9 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 CCD25221.1 - 1.5e-06 27.5 0.1 0.0056 15.7 0.0 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCD25221.1 - 1.4e-05 24.8 0.0 0.00031 20.5 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF2127 PF09900.4 CCD25221.1 - 0.089 12.8 0.1 0.25 11.3 0.1 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2127) Sel1 PF08238.7 CCD25221.1 - 2.4 8.9 5.1 80 4.0 0.1 4.7 5 0 0 5 5 4 0 Sel1 repeat SAM_2 PF07647.12 CCD25222.1 - 4.3e-13 48.8 0.2 8.7e-13 47.9 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH PF00169.24 CCD25222.1 - 4e-11 43.0 0.1 4e-11 43.0 0.1 3.1 3 2 0 3 3 3 1 PH domain SH3_1 PF00018.23 CCD25222.1 - 7.1e-10 38.1 0.3 1.6e-09 36.9 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCD25222.1 - 1.8e-08 33.8 0.1 4.2e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 CCD25222.1 - 7.4e-08 32.3 0.5 2.2e-06 27.6 0.0 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain SH3_2 PF07653.12 CCD25222.1 - 3.3e-07 29.6 0.0 9.1e-07 28.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain PH_11 PF15413.1 CCD25222.1 - 9.2e-06 25.8 0.1 9.2e-06 25.8 0.1 4.0 3 1 0 3 3 3 1 Pleckstrin homology domain SAM_1 PF00536.25 CCD25222.1 - 1.5e-05 25.0 0.2 3.9e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NT-C2 PF10358.4 CCD25223.1 - 1.8e-38 131.2 7.7 2.5e-38 130.7 3.2 2.5 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins PAP2 PF01569.16 CCD25224.1 - 2.2e-13 49.9 8.4 2.2e-13 49.9 5.9 2.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CCD25224.1 - 3e-05 23.6 8.2 3e-05 23.6 5.7 2.3 1 1 0 2 2 2 1 PAP2 superfamily DUF912 PF06024.7 CCD25224.1 - 0.1 12.6 0.2 0.28 11.2 0.1 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PAP2_C PF14360.1 CCD25224.1 - 8.1 6.8 16.2 0.43 10.8 5.6 2.6 2 0 0 2 2 2 0 PAP2 superfamily C-terminal ALG3 PF05208.8 CCD25225.1 - 1.2e-121 406.4 30.0 1.6e-121 406.0 20.8 1.2 1 0 0 1 1 1 1 ALG3 protein PH_4 PF15404.1 CCD25225.1 - 0.039 13.4 0.1 0.093 12.2 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain LisH PF08513.6 CCD25226.1 - 0.00021 20.9 0.2 0.00051 19.7 0.1 1.7 1 0 0 1 1 1 1 LisH SR-25 PF10500.4 CCD25227.1 - 0.0011 18.5 1.0 0.0011 18.5 0.7 2.5 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein MCM PF00493.18 CCD25227.1 - 0.89 8.2 3.5 1.4 7.6 2.5 1.3 1 0 0 1 1 1 0 MCM2/3/5 family GatB_N PF02934.10 CCD25228.1 - 2.3e-91 305.6 0.1 3e-91 305.2 0.1 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 CCD25228.1 - 2.8e-24 85.5 5.0 5.4e-24 84.5 3.4 1.5 1 0 0 1 1 1 1 GatB domain DUF3252 PF11623.3 CCD25228.1 - 0.093 12.1 0.1 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3252) Nucleoporin_C PF03177.9 CCD25229.1 - 1e-119 400.7 22.2 1.4e-119 400.3 15.4 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CCD25229.1 - 1.7e-100 336.7 16.2 1.7e-100 336.7 11.2 2.2 2 0 0 2 2 2 1 Nup133 N terminal like Atg8 PF02991.11 CCD25230.1 - 1.4e-49 166.3 0.1 1.6e-49 166.1 0.1 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CCD25230.1 - 2.1e-05 24.6 0.0 2.6e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 tRNA-synt_1 PF00133.17 CCD25231.1 - 2.9e-239 795.1 1.1 2e-238 792.2 0.1 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCD25231.1 - 2.6e-27 95.4 0.2 9.4e-27 93.6 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCD25231.1 - 1.1e-18 67.1 3.9 3.4e-06 25.9 0.6 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CCD25231.1 - 0.00065 18.9 0.0 0.0018 17.4 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF2766 PF10964.3 CCD25231.1 - 0.2 11.5 1.5 4.9 7.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2766) HSP70 PF00012.15 CCD25232.1 - 1e-265 882.3 8.3 1.2e-265 882.2 5.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCD25232.1 - 8.8e-16 57.4 0.0 1.8e-14 53.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CCD25232.1 - 0.0016 18.0 0.0 0.0032 17.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CCD25232.1 - 0.0081 15.0 1.2 0.41 9.4 0.1 2.9 2 1 1 3 3 3 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CCD25232.1 - 0.69 8.9 5.2 0.27 10.3 0.1 2.7 3 1 1 4 4 4 0 Hydantoinase/oxoprolinase Ribosomal_S8e PF01201.17 CCD25233.1 - 6.8e-51 171.8 2.6 7.8e-51 171.6 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 CCD25233.1 - 0.097 12.9 1.1 0.19 12.0 0.1 1.9 2 0 0 2 2 2 0 Small acidic protein family UQ_con PF00179.21 CCD25234.1 - 7.9e-29 99.8 0.1 1.6e-28 98.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCD25234.1 - 0.0038 17.0 0.2 0.0084 15.9 0.1 1.6 1 0 0 1 1 1 1 RWD domain DUF4484 PF14831.1 CCD25234.1 - 0.016 15.3 0.9 0.022 14.8 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4484) Orthopox_B11R PF07033.6 CCD25234.1 - 0.056 12.9 10.2 0.16 11.4 4.0 2.2 1 1 1 2 2 2 0 Orthopoxvirus B11R protein UCH PF00443.24 CCD25235.1 - 1.9e-66 223.9 31.3 2.2e-66 223.7 14.3 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCD25235.1 - 1.3e-25 90.4 10.7 5.9e-24 85.0 2.6 4.1 3 1 1 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase Fungal_trans PF04082.13 CCD25236.1 - 3.1e-27 95.0 1.5 3.1e-27 95.0 1.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD25236.1 - 1.7e-09 37.3 9.8 2.9e-09 36.6 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.16 CCD25237.1 - 2.4e-33 114.4 0.1 3.5e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 CCD25237.1 - 9e-13 47.6 0.0 2.1e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 CCD25237.1 - 2.3e-09 36.9 0.0 3.9e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Redoxin TatD_DNase PF01026.16 CCD25238.1 - 1.8e-39 135.4 0.0 2.7e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase PP2C PF00481.16 CCD25239.1 - 8.1e-67 225.2 0.1 1.4e-66 224.5 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 CCD25239.1 - 4.7e-05 22.8 0.0 0.00013 21.4 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 CCD25239.1 - 0.0042 16.8 0.0 0.034 13.8 0.0 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Ribosomal_S15 PF00312.17 CCD25239.1 - 0.0076 15.9 0.3 0.026 14.2 0.2 1.9 1 0 0 1 1 1 1 Ribosomal protein S15 P4Ha_N PF08336.6 CCD25239.1 - 0.012 15.4 1.0 0.061 13.1 0.1 2.3 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Scm3 PF10384.4 CCD25240.1 - 0.023 14.1 2.1 0.037 13.5 0.3 2.2 2 0 0 2 2 2 0 Centromere protein Scm3 PTH2 PF01981.11 CCD25241.1 - 2.3e-44 149.7 0.5 4.7e-44 148.7 0.0 1.7 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 DUF2421 PF10334.4 CCD25241.1 - 0.017 14.7 0.1 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2421) Myc_N PF01056.13 CCD25241.1 - 0.021 14.0 2.4 0.026 13.7 1.7 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Ycf1 PF05758.7 CCD25241.1 - 0.029 12.1 0.4 0.029 12.1 0.3 1.0 1 0 0 1 1 1 0 Ycf1 SEP PF08059.8 CCD25242.1 - 6.6e-27 93.6 0.3 1.7e-26 92.3 0.2 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 CCD25242.1 - 4.6e-16 58.6 0.1 8e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CCD25242.1 - 2.7e-08 33.1 0.8 5.1e-08 32.3 0.6 1.5 1 0 0 1 1 1 1 UBA-like domain Cmc1 PF08583.5 CCD25244.1 - 5.1e-17 61.3 7.3 5.1e-17 61.3 5.1 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CCD25244.1 - 0.02 14.8 3.2 2.5 8.1 0.1 2.4 2 0 0 2 2 2 0 CHCH domain CBM_14 PF01607.19 CCD25244.1 - 0.056 13.3 0.7 0.087 12.7 0.5 1.3 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain NDUF_B7 PF05676.8 CCD25244.1 - 0.15 11.4 2.3 0.29 10.5 1.6 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Sec7 PF01369.15 CCD25245.1 - 4.8e-25 88.3 3.3 2e-24 86.3 2.3 2.1 1 0 0 1 1 1 1 Sec7 domain DASH_Dad2 PF08654.5 CCD25245.1 - 0.012 15.5 0.8 0.1 12.6 0.1 2.9 2 0 0 2 2 2 0 DASH complex subunit Dad2 DUF3439 PF11921.3 CCD25245.1 - 0.17 11.6 5.2 0.51 10.0 3.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 CCD25245.1 - 1.9 8.2 13.6 3.2 7.5 8.3 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Sel1 PF08238.7 CCD25246.1 - 2e-41 139.5 19.6 9.3e-10 38.8 0.1 7.8 8 0 0 8 8 8 7 Sel1 repeat Kinesin PF00225.18 CCD25247.1 - 2.7e-107 358.3 3.3 2.7e-107 358.3 2.3 3.3 4 1 0 4 4 4 1 Kinesin motor domain DUF2564 PF10819.3 CCD25247.1 - 7.7 6.7 14.7 0.14 12.2 0.6 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2564) Myb_DNA-bind_6 PF13921.1 CCD25248.1 - 1.1e-12 47.7 4.0 1.2e-11 44.5 0.7 3.2 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCD25248.1 - 7.8e-08 32.2 3.4 1.9e-07 31.0 0.5 2.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain Rap1_C PF11626.3 CCD25248.1 - 0.01 15.7 0.7 0.64 9.9 0.0 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 CCD25248.1 - 0.96 9.6 6.5 3.4 7.8 0.5 3.1 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Exo5 PF09810.4 CCD25248.1 - 2.6 7.2 12.1 0.18 11.0 4.3 1.9 2 0 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease Transp_cyt_pur PF02133.10 CCD25249.1 - 1.2e-96 323.9 34.3 1.4e-96 323.7 23.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 CCD25250.1 - 2.2e-92 309.9 40.1 2.5e-92 309.7 27.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HisG PF01634.13 CCD25251.1 - 3.9e-53 179.3 0.2 5.8e-53 178.8 0.2 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 CCD25251.1 - 6.4e-27 93.3 0.0 1e-26 92.6 0.0 1.3 1 0 0 1 1 1 1 HisG, C-terminal domain CBM_21 PF03370.8 CCD25252.1 - 2.3e-29 101.6 1.2 2.3e-29 101.6 0.9 2.0 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit Mito_carr PF00153.22 CCD25254.1 - 7.6e-49 163.3 7.4 3.3e-18 65.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein MMR1 PF08505.5 CCD25255.1 - 3.4e-10 40.3 37.1 3.4e-10 40.3 25.7 5.0 2 2 2 4 4 4 1 Mitochondrial Myo2 receptor-related protein MtrB PF05440.7 CCD25255.1 - 0.6 10.1 2.4 24 5.0 0.2 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Peroxin-13_N PF04088.8 CCD25256.1 - 2.7e-55 186.6 0.4 5.3e-55 185.7 0.3 1.5 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_1 PF00018.23 CCD25256.1 - 7.2e-10 38.0 0.1 1.5e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCD25256.1 - 5.3e-08 32.3 0.0 1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCD25256.1 - 1.1e-07 31.2 0.0 2.5e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CCD25256.1 - 0.0041 17.2 0.0 0.0093 16.1 0.0 1.6 1 0 0 1 1 1 1 Bacterial SH3 domain eIF3_subunit PF08597.5 CCD25257.1 - 7.5e-57 192.7 14.8 9.5e-57 192.3 10.3 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PRELI PF04707.9 CCD25258.1 - 1.5e-49 167.6 0.6 1.7e-49 167.3 0.4 1.0 1 0 0 1 1 1 1 PRELI-like family DUF4393 PF14337.1 CCD25258.1 - 0.011 15.1 0.2 0.016 14.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4393) NMT PF01233.14 CCD25260.1 - 8.8e-85 282.2 0.1 2.4e-84 280.8 0.1 1.8 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 CCD25260.1 - 4.7e-75 251.1 4.0 9.1e-75 250.2 2.8 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 CCD25260.1 - 1.4e-05 24.9 0.0 0.00033 20.5 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCD25260.1 - 0.00019 21.6 0.0 0.0018 18.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain WD40 PF00400.27 CCD25261.1 - 1.7e-12 46.7 5.9 9.7e-06 25.2 0.1 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 CCD25261.1 - 0.00036 18.8 0.1 0.0011 17.1 0.0 1.8 2 0 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CCD25261.1 - 0.12 12.6 0.0 2.2 8.6 0.0 2.8 3 0 0 3 3 3 0 PQQ-like domain SUKH_6 PF14568.1 CCD25261.1 - 0.14 12.6 0.1 0.14 12.6 0.1 2.2 2 1 1 3 3 3 0 SMI1-KNR4 cell-wall POC1 PF10450.4 CCD25262.1 - 6.5e-73 244.8 0.5 7.3e-73 244.6 0.4 1.0 1 0 0 1 1 1 1 POC1 chaperone Prefoldin_2 PF01920.15 CCD25263.1 - 4.1e-25 87.6 8.9 4.3e-25 87.5 6.2 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF1192 PF06698.6 CCD25263.1 - 0.0055 16.4 0.3 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) DUF1732 PF08340.6 CCD25263.1 - 0.01 15.6 2.0 0.017 14.9 1.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) MIP-T3 PF10243.4 CCD25263.1 - 0.018 13.5 3.0 0.029 12.8 2.1 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Prefoldin PF02996.12 CCD25263.1 - 0.023 14.3 4.8 0.027 14.1 0.3 2.0 1 1 0 2 2 2 0 Prefoldin subunit HrpB7 PF09486.5 CCD25263.1 - 0.046 13.6 1.4 1.8 8.4 0.2 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) SLAM PF06214.6 CCD25263.1 - 0.064 13.1 0.1 0.074 12.9 0.1 1.2 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein Guanylin PF02058.10 CCD25263.1 - 0.1 12.7 0.3 0.17 11.9 0.2 1.5 1 1 0 1 1 1 0 Guanylin precursor CENP-F_leu_zip PF10473.4 CCD25263.1 - 0.1 12.4 6.8 1.1 9.0 0.4 2.1 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 CCD25263.1 - 0.16 11.4 6.1 0.16 11.3 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Med4 PF10018.4 CCD25263.1 - 0.37 10.1 4.8 0.13 11.7 0.9 1.7 2 0 0 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 IncA PF04156.9 CCD25263.1 - 0.44 10.1 8.7 11 5.5 6.0 2.0 1 1 0 1 1 1 0 IncA protein YgaB PF14182.1 CCD25263.1 - 0.51 10.6 9.2 0.25 11.6 1.8 2.9 1 1 1 2 2 2 0 YgaB-like protein Spc24 PF08286.6 CCD25263.1 - 0.78 9.4 8.4 3.9 7.1 1.1 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Atg14 PF10186.4 CCD25263.1 - 1 8.2 6.1 1.3 7.8 4.2 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 FliJ PF02050.11 CCD25263.1 - 1.6 8.7 7.3 2.9 7.9 0.8 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein Med9 PF07544.8 CCD25263.1 - 1.8 8.3 5.8 0.92 9.2 1.0 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 GrpE PF01025.14 CCD25263.1 - 1.8 8.0 6.2 0.54 9.7 1.2 1.9 1 1 1 2 2 2 0 GrpE COQ9 PF08511.6 CCD25264.1 - 7.2e-17 60.6 0.2 1.7e-16 59.4 0.0 1.8 2 0 0 2 2 2 1 COQ9 zf-Mss51 PF13824.1 CCD25265.1 - 1.4e-18 66.4 3.0 2.2e-17 62.6 0.9 2.5 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.6 CCD25265.1 - 0.0076 15.7 0.2 0.025 14.1 0.2 1.9 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF1713 PF08213.6 CCD25266.1 - 1.1e-12 47.2 25.3 1.7e-12 46.6 17.5 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) U3_assoc_6 PF08640.6 CCD25266.1 - 9.7e-05 22.0 1.5 0.0013 18.4 0.3 2.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 Heme_oxygenase PF01126.15 CCD25267.1 - 2e-13 50.4 5.9 2.9e-11 43.3 4.1 2.8 1 1 0 1 1 1 1 Heme oxygenase MRP-S28 PF10213.4 CCD25267.1 - 0.00059 19.9 0.8 0.00059 19.9 0.6 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein DUF1044 PF06296.7 CCD25267.1 - 0.11 12.3 0.9 0.25 11.1 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1044) Ribosomal_S18 PF01084.15 CCD25268.1 - 2e-16 59.5 0.9 9.7e-16 57.3 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S18 Ofd1_CTDD PF10637.4 CCD25269.1 - 1.3e-88 296.6 6.8 7e-84 281.0 4.3 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 CCD25269.1 - 1.4e-15 57.5 0.1 3.7e-15 56.2 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Complex1_LYR_1 PF13232.1 CCD25270.1 - 1.5e-14 53.9 3.6 2e-14 53.5 2.5 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CCD25270.1 - 2.7e-14 52.6 2.8 3.8e-14 52.2 1.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) MIF4G PF02854.14 CCD25270.1 - 0.026 13.9 2.7 0.041 13.2 1.9 1.3 1 1 0 1 1 1 0 MIF4G domain DNA_pol_B_exo1 PF03104.14 CCD25270.1 - 0.03 13.1 0.4 0.037 12.8 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase family B, exonuclease domain Complex1_LYR_2 PF13233.1 CCD25270.1 - 0.041 14.3 2.3 0.046 14.1 1.6 1.1 1 0 0 1 1 1 0 Complex1_LYR-like ChlamPMP_M PF07548.6 CCD25271.1 - 0.11 12.2 0.9 0.14 11.8 0.6 1.4 1 1 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain RE_Eco47II PF09553.5 CCD25272.1 - 0.097 11.7 0.6 0.24 10.4 0.4 1.7 1 1 0 1 1 1 0 Eco47II restriction endonuclease DnaJ-X PF14308.1 CCD25273.1 - 2.2e-60 203.4 13.6 2.2e-60 203.4 9.4 1.8 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CCD25273.1 - 4.7e-26 90.3 0.4 4.7e-26 90.3 0.3 2.9 4 0 0 4 4 4 1 DnaJ domain Metal_resist PF13801.1 CCD25273.1 - 0.049 13.6 0.6 0.64 10.0 0.2 2.3 2 0 0 2 2 2 0 Heavy-metal resistance TAFII28 PF04719.9 CCD25273.1 - 0.64 9.8 8.6 0.8 9.5 0.6 3.1 3 0 0 3 3 3 0 hTAFII28-like protein conserved region Arrestin_C PF02752.17 CCD25274.1 - 2.4e-15 56.8 5.1 2.4e-15 56.8 3.5 5.4 3 3 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCD25274.1 - 0.0028 17.4 0.1 0.011 15.5 0.1 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Got1 PF04178.7 CCD25275.1 - 2.3e-30 105.0 20.6 3.3e-30 104.6 14.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1049 PF06305.6 CCD25275.1 - 4.9 6.7 5.6 0.75 9.3 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) HLH PF00010.21 CCD25276.1 - 5.1e-12 45.3 0.1 1.1e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SopA PF13981.1 CCD25277.1 - 0.017 15.1 1.2 0.066 13.2 0.1 2.4 2 0 0 2 2 2 0 SopA-like central domain zf-RING_2 PF13639.1 CCD25277.1 - 0.043 13.6 9.4 0.11 12.3 2.4 3.0 3 0 0 3 3 3 0 Ring finger domain Pkinase PF00069.20 CCD25278.1 - 7.8e-63 212.0 0.0 2e-62 210.6 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25278.1 - 7.6e-35 120.2 0.0 1.7e-34 119.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 CCD25278.1 - 3.9e-27 93.7 12.0 7.6e-16 57.6 3.5 2.8 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 CCD25278.1 - 1.1e-18 66.6 38.3 1.1e-10 41.0 10.4 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CCD25278.1 - 1.4e-12 47.9 2.0 6.7e-12 45.7 1.4 2.3 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.25 CCD25278.1 - 0.00048 19.9 0.0 0.0017 18.1 0.0 1.9 1 0 0 1 1 1 1 C2 domain zf-tcix PF14952.1 CCD25278.1 - 3.9 6.8 11.1 0.5 9.7 1.2 2.7 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding DUF4206 PF13901.1 CCD25278.1 - 9.1 5.7 29.3 0.46 9.9 5.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4206) Lgl_C PF08596.5 CCD25279.1 - 2.3e-140 467.5 0.7 6.1e-140 466.1 0.3 1.8 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CCD25279.1 - 0.0032 17.2 0.3 8.2 6.4 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCD25279.1 - 0.091 12.2 0.3 4.3 6.9 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Cid2 PF09774.4 CCD25280.1 - 3.7e-33 114.7 8.3 4.9e-33 114.3 5.7 1.2 1 0 0 1 1 1 1 Caffeine-induced death protein 2 AIM24 PF01987.12 CCD25281.1 - 2.7e-06 26.9 0.0 0.0067 15.9 0.0 2.9 1 1 1 2 2 2 2 Mitochondrial biogenesis AIM24 NuA4 PF09340.5 CCD25282.1 - 2e-20 72.2 7.3 5.3e-11 41.9 1.6 2.7 2 0 0 2 2 2 2 Histone acetyltransferase subunit NuA4 Use1 PF09753.4 CCD25282.1 - 0.041 13.3 0.2 0.076 12.4 0.1 1.5 1 0 0 1 1 1 0 Membrane fusion protein Use1 FAM217 PF15344.1 CCD25282.1 - 0.054 13.0 4.3 0.043 13.3 2.2 1.3 1 1 0 1 1 1 0 FAM217 family YtzH PF14165.1 CCD25282.1 - 0.64 10.2 3.8 0.83 9.9 0.0 2.4 2 0 0 2 2 2 0 YtzH-like protein DivIVA PF05103.8 CCD25282.1 - 1.6 8.8 6.4 0.69 9.9 1.0 2.1 2 0 0 2 2 2 0 DivIVA protein IncA PF04156.9 CCD25282.1 - 3.7 7.0 4.9 6.6 6.2 3.4 1.3 1 0 0 1 1 1 0 IncA protein SAP25 PF15476.1 CCD25282.1 - 5.6 6.4 6.0 1.7 8.0 0.3 2.0 1 1 1 2 2 2 0 Histone deacetylase complex subunit SAP25 IncA PF04156.9 CCD25283.1 - 0.57 9.7 2.6 1.5 8.3 1.8 1.7 1 0 0 1 1 1 0 IncA protein PCI PF01399.22 CCD25284.1 - 1e-10 41.8 2.3 7.7e-05 22.9 0.0 3.2 3 0 0 3 3 3 2 PCI domain YmgB PF10798.3 CCD25284.1 - 0.89 9.4 4.0 0.77 9.6 0.2 2.5 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR Tmemb_14 PF03647.8 CCD25286.1 - 1.2e-12 48.0 7.0 1.4e-12 47.8 4.9 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1282 PF06930.7 CCD25286.1 - 0.061 12.9 2.4 0.095 12.3 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) AA_kinase PF00696.23 CCD25287.1 - 2.5e-39 135.2 0.0 3.9e-39 134.6 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 CCD25287.1 - 5.9e-14 51.1 0.3 1.5e-07 30.7 0.1 3.0 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 CCD25287.1 - 8.1e-09 34.8 1.6 2.4e-06 26.9 0.2 2.6 2 0 0 2 2 2 2 ACT domain hNIFK_binding PF12196.3 CCD25288.1 - 0.15 11.4 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK DUF3644 PF12358.3 CCD25288.1 - 0.54 10.5 3.4 1.6 9.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3644) Sec61_beta PF03911.11 CCD25289.1 - 2.1e-18 65.7 1.2 2.7e-18 65.4 0.8 1.1 1 0 0 1 1 1 1 Sec61beta family MOZ_SAS PF01853.13 CCD25290.1 - 1.3e-68 229.9 5.4 3.4e-67 225.3 3.8 2.3 1 1 0 1 1 1 1 MOZ/SAS family Ribosomal_L34e PF01199.13 CCD25291.1 - 9.1e-37 125.1 3.8 9.1e-37 125.1 2.6 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e EndIII_4Fe-2S PF10576.4 CCD25291.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.2 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Ribonuc_L-PSP PF01042.16 CCD25292.1 - 8.8e-41 138.4 0.5 9.8e-41 138.3 0.3 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Cyclin PF08613.6 CCD25294.1 - 6.5e-26 91.5 3.1 5.6e-25 88.4 2.1 2.2 1 1 0 1 1 1 1 Cyclin NAAA-beta PF15508.1 CCD25294.1 - 0.11 12.9 0.1 45 4.4 0.0 3.3 1 1 2 3 3 3 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Transp_cyt_pur PF02133.10 CCD25295.1 - 1e-95 320.9 34.8 1.2e-95 320.7 24.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ketoacyl-synt PF00109.21 CCD25296.1 - 4.8e-52 176.9 0.0 6.6e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CCD25296.1 - 9.4e-34 115.8 0.0 1.5e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 CCD25296.1 - 0.00094 18.2 0.2 0.0017 17.4 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain HAD_2 PF13419.1 CCD25297.1 - 2.4e-11 44.1 0.0 3.3e-11 43.7 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCD25297.1 - 1.7e-07 31.8 0.0 3.7e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCD25297.1 - 3.8e-07 29.7 0.0 7.8e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CCD25297.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Vhr1 PF04001.8 CCD25298.1 - 1.3e-48 162.8 4.8 2.7e-48 161.7 3.3 1.5 1 0 0 1 1 1 1 Transcription factor Vhr1 Sen15 PF09631.5 CCD25298.1 - 0.034 14.3 1.5 1.3 9.3 0.1 2.9 2 1 0 2 2 2 0 Sen15 protein ICL PF00463.16 CCD25299.1 - 1.3e-270 898.0 0.6 1.5e-270 897.8 0.4 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CCD25299.1 - 1.8e-10 40.4 0.0 3.6e-10 39.4 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Flo11 PF10182.4 CCD25300.1 - 7.1e-53 178.2 4.1 1.2e-52 177.5 2.8 1.4 1 0 0 1 1 1 1 Flo11 domain DUF2578 PF10843.3 CCD25301.1 - 1.2e-55 188.2 16.8 1.4e-55 188.0 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) Thiol_cytolysin PF01289.14 CCD25301.1 - 0.043 12.1 0.1 0.06 11.7 0.0 1.1 1 0 0 1 1 1 0 Thiol-activated cytolysin Myosin_head PF00063.16 CCD25301.1 - 0.091 10.7 1.8 0.11 10.4 1.2 1.1 1 0 0 1 1 1 0 Myosin head (motor domain) zf-RING_4 PF14570.1 CCD25302.1 - 9.3e-20 69.9 12.9 1.8e-19 69.0 8.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 CCD25302.1 - 4.7e-08 32.7 0.0 1.2e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 CCD25302.1 - 1.8e-06 27.3 8.9 2e-05 23.9 0.5 3.3 3 0 0 3 3 3 2 Rtf2 RING-finger RRM_1 PF00076.17 CCD25302.1 - 8.5e-06 25.3 0.0 3.5e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CCD25302.1 - 9.2e-06 25.2 6.1 1.9e-05 24.2 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 CCD25302.1 - 8.4e-05 22.3 3.1 0.00019 21.1 2.2 1.5 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_6 PF14259.1 CCD25302.1 - 0.00076 19.4 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 CCD25302.1 - 0.002 17.9 8.8 0.0039 16.9 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCD25302.1 - 0.0073 15.9 10.4 0.016 14.8 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SET_assoc PF11767.3 CCD25302.1 - 0.016 14.5 0.0 0.055 12.7 0.0 1.9 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated zf-UDP PF14569.1 CCD25302.1 - 0.031 14.0 3.9 0.074 12.8 2.7 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.1 CCD25302.1 - 0.087 12.5 9.4 0.18 11.5 6.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCD25302.1 - 0.8 9.7 10.9 1.6 8.7 7.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCD25302.1 - 0.99 9.3 10.7 10 6.0 7.5 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Peptidase_S49_N PF08496.5 CCD25302.1 - 3.3 7.4 12.9 0.52 10.1 0.1 3.3 3 0 0 3 3 3 0 Peptidase family S49 N-terminal U1snRNP70_N PF12220.3 CCD25303.1 - 2.2e-16 59.9 0.2 4.7e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 CCD25303.1 - 5e-16 58.0 0.0 1.2e-15 56.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD25303.1 - 1.5e-10 40.9 0.1 2.9e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD25303.1 - 4.4e-05 23.2 0.1 7.6e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF619 PF04768.8 CCD25304.1 - 1.3e-52 177.6 0.9 1.9e-52 177.0 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 CCD25304.1 - 1.2e-28 99.8 0.0 2.5e-28 98.7 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 CCD25304.1 - 5.6e-17 62.0 0.1 1e-16 61.2 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 CCD25304.1 - 0.012 15.4 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus P16-Arc PF04699.9 CCD25305.1 - 4.8e-51 172.7 0.0 5.3e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Utp12 PF04003.7 CCD25305.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Dip2/Utp12 Family Ribonuc_red_lgC PF02867.10 CCD25306.1 - 8.5e-215 714.3 0.0 1.1e-214 714.0 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CCD25306.1 - 3.5e-23 81.1 0.0 8.6e-23 79.9 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CCD25306.1 - 5e-16 58.9 0.3 1.8e-15 57.1 0.0 2.2 2 0 0 2 2 2 1 ATP cone domain Sec6 PF06046.8 CCD25307.1 - 4.9e-155 516.8 8.5 9e-155 515.9 5.9 1.4 1 0 0 1 1 1 1 Exocyst complex component Sec6 Tctex-1 PF03645.8 CCD25308.1 - 2.3e-08 33.8 0.8 2.6e-08 33.6 0.5 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 CCD25309.1 - 5.4e-14 52.1 4.7 5.8e-14 52.0 1.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LHC PF00556.15 CCD25309.1 - 0.014 15.1 0.2 0.05 13.4 0.2 1.9 1 0 0 1 1 1 0 Antenna complex alpha/beta subunit Aldedh PF00171.17 CCD25310.1 - 2.9e-185 616.0 0.1 3.2e-185 615.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ETRAMP PF09716.5 CCD25312.1 - 9.4 6.2 9.9 0.62 10.0 0.7 3.0 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) HA2 PF04408.18 CCD25313.1 - 1.3e-23 82.8 0.0 5.1e-23 81.0 0.0 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCD25313.1 - 2.6e-21 75.5 0.0 9.3e-21 73.7 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCD25313.1 - 1.8e-14 53.3 0.0 4.5e-14 52.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD25313.1 - 6.4e-07 29.0 0.1 1.5e-06 27.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCD25313.1 - 8.3e-07 29.2 0.1 2.5e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 CCD25313.1 - 0.00023 21.0 6.6 0.062 13.1 0.0 3.9 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit T2SE PF00437.15 CCD25313.1 - 0.00059 18.8 0.1 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 CCD25313.1 - 0.0051 16.7 3.9 0.026 14.4 0.5 3.4 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CCD25313.1 - 0.0056 16.9 0.0 0.021 15.1 0.0 2.1 1 0 0 1 1 1 1 ABC transporter KaiC PF06745.8 CCD25313.1 - 0.0081 15.2 0.2 0.026 13.6 0.1 1.6 1 1 0 1 1 1 1 KaiC AAA_19 PF13245.1 CCD25313.1 - 0.0094 15.6 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain SRP54 PF00448.17 CCD25313.1 - 0.014 14.8 0.1 0.032 13.6 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 CCD25313.1 - 0.027 14.0 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CCD25313.1 - 0.043 14.3 0.0 0.22 12.0 0.0 2.3 1 0 0 1 1 1 0 Miro-like protein IstB_IS21 PF01695.12 CCD25313.1 - 0.058 12.8 0.0 6 6.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 CCD25313.1 - 0.098 12.2 0.0 0.31 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Flavi_DEAD PF07652.9 CCD25313.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Peptidase_M48 PF01435.13 CCD25314.1 - 2.6e-32 112.1 0.0 3.6e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 SNARE_assoc PF09335.6 CCD25315.1 - 6.5e-16 58.6 5.4 6.5e-16 58.6 3.7 2.6 2 1 1 3 3 3 1 SNARE associated Golgi protein DUF1469 PF07332.6 CCD25315.1 - 0.17 11.6 2.4 11 5.7 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) DUF996 PF06195.8 CCD25315.1 - 1.2 9.1 9.9 2.3 8.2 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF996) DUF3336 PF11815.3 CCD25316.1 - 1e-37 128.8 7.2 1e-37 128.8 5.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CCD25316.1 - 1.3e-29 103.6 0.1 6.4e-29 101.3 0.0 2.3 2 0 0 2 2 2 1 Patatin-like phospholipase LIM PF00412.17 CCD25317.1 - 6.5e-15 54.9 25.9 1.6e-09 37.6 6.3 2.5 2 0 0 2 2 2 2 LIM domain SRP40_C PF05022.7 CCD25318.1 - 2.6e-30 104.7 4.0 2.6e-30 104.7 2.8 2.3 2 0 0 2 2 2 1 SRP40, C-terminal domain PTR2 PF00854.16 CCD25319.1 - 3.6e-61 206.9 15.9 4.6e-61 206.6 11.0 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 CCD25319.1 - 1e-09 37.6 36.6 5.8e-09 35.1 17.7 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Arc_PepC_II PF06847.6 CCD25319.1 - 1.2 9.5 4.3 2.4 8.6 0.0 3.0 3 0 0 3 3 3 0 Archaeal Peptidase A24 C-terminus Type II ubiquitin PF00240.18 CCD25320.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CCD25320.1 - 3.2e-31 106.6 10.7 5.1e-31 106.0 7.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CCD25320.1 - 4.7e-20 71.0 0.7 6.5e-20 70.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCD25320.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCD25320.1 - 0.00011 21.9 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCD25320.1 - 0.0079 16.0 0.1 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCD25320.1 - 0.013 15.6 0.1 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 CCD25320.1 - 0.28 11.0 1.7 1.2 8.9 1.1 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain TPR_MLP1_2 PF07926.7 CCD25321.1 - 6.9e-22 77.6 25.6 6.9e-22 77.6 17.8 16.6 5 3 11 17 17 17 6 TPR/MLP1/MLP2-like protein DUF948 PF06103.6 CCD25321.1 - 0.0082 15.9 0.9 0.0082 15.9 0.7 14.8 10 4 8 19 19 19 1 Bacterial protein of unknown function (DUF948) MtrB PF05440.7 CCD25321.1 - 4.6 7.3 11.6 1.5 8.8 0.1 5.9 5 0 0 5 5 5 0 Tetrahydromethanopterin S-methyltransferase subunit B DAGK_cat PF00781.19 CCD25322.1 - 5e-09 35.6 0.0 9.3e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Pcc1 PF09341.5 CCD25323.1 - 2.1e-20 72.5 0.0 2.7e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 PEPCK_ATP PF01293.15 CCD25325.1 - 1.3e-218 726.2 0.0 1.5e-218 725.9 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 CCD25325.1 - 0.013 15.3 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCD25325.1 - 0.032 13.7 0.0 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 CCD25325.1 - 0.044 12.8 0.1 0.092 11.8 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 CCD25325.1 - 0.099 12.0 0.1 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Myb_DNA-bind_6 PF13921.1 CCD25326.1 - 8.9e-27 92.9 12.8 1.5e-10 40.9 0.0 4.1 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCD25326.1 - 2.1e-26 91.7 8.0 1.7e-12 47.1 0.1 4.4 3 1 0 3 3 3 3 Myb-like DNA-binding domain SKG6 PF08693.5 CCD25327.1 - 0.0056 15.9 2.3 0.0056 15.9 1.6 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 CCD25327.1 - 0.071 12.6 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DEAD PF00270.24 CCD25328.1 - 5.7e-09 35.6 0.0 6.7e-08 32.2 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Sir1 PF11603.3 CCD25328.1 - 0.0077 16.3 0.9 0.014 15.5 0.6 1.5 1 0 0 1 1 1 1 Regulatory protein Sir1 GST_N_2 PF13409.1 CCD25329.1 - 7.6e-13 48.2 0.0 8.3e-12 44.9 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCD25329.1 - 6.6e-05 22.7 0.0 0.00013 21.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCD25329.1 - 0.012 15.8 0.0 0.044 14.0 0.0 2.0 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Zn_clus PF00172.13 CCD25330.1 - 1.2e-09 37.8 11.0 1.2e-09 37.8 7.6 2.4 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 CCD25331.1 - 3.2e-58 197.1 0.3 3.6e-58 197.0 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain PQ-loop PF04193.9 CCD25332.1 - 3.2e-21 74.6 16.2 6.7e-20 70.4 2.1 3.2 3 1 0 3 3 3 2 PQ loop repeat Epiglycanin_C PF14654.1 CCD25332.1 - 0.085 12.8 7.7 0.15 12.0 0.2 3.3 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region ABC2_membrane_5 PF13346.1 CCD25332.1 - 2.5 7.3 22.3 0.29 10.4 6.7 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein Cys_Met_Meta_PP PF01053.15 CCD25333.1 - 9e-58 195.3 0.0 2.1e-57 194.2 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CCD25333.1 - 0.00011 21.0 0.0 0.00029 19.7 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Hyphal_reg_CWP PF11765.3 CCD25334.1 - 1.8e-22 79.5 20.4 1.8e-22 79.5 14.1 2.5 3 0 0 3 3 3 1 Hyphally regulated cell wall protein N-terminal FH2 PF02181.18 CCD25335.1 - 7.3e-66 222.5 12.1 7.3e-66 222.5 8.4 2.7 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 CCD25335.1 - 5.9e-10 38.8 0.8 5.9e-10 38.8 0.5 3.0 3 1 1 4 4 4 1 Diaphanous GTPase-binding Domain Coa1 PF08695.5 CCD25336.1 - 1e-37 128.2 0.0 1.5e-37 127.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF1748 PF08520.5 CCD25337.1 - 7.5e-30 102.3 0.0 8.2e-30 102.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) MOR2-PAG1_N PF14222.1 CCD25338.1 - 4.9e-180 599.8 15.4 4.9e-180 599.8 10.7 2.8 3 1 1 4 4 4 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 CCD25338.1 - 2e-94 316.2 8.8 2.1e-94 316.1 1.3 3.8 3 0 0 3 3 3 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 CCD25338.1 - 6.4e-22 77.0 14.2 1.3e-10 39.6 0.3 3.3 2 1 1 3 3 3 3 Cell morphogenesis central region MAT1 PF06391.8 CCD25338.1 - 0.62 9.6 10.2 0.046 13.3 1.9 2.4 2 0 0 2 2 2 0 CDK-activating kinase assembly factor MAT1 UCH PF00443.24 CCD25339.1 - 2e-60 204.1 5.9 2e-60 204.1 4.1 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCD25339.1 - 3.1e-31 108.9 5.9 3.1e-31 108.9 4.1 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 CCD25339.1 - 0.00059 20.1 0.0 0.0028 17.9 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain DUF3094 PF11293.3 CCD25339.1 - 0.16 11.4 2.6 0.45 10.0 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) DAO PF01266.19 CCD25340.1 - 5e-51 173.6 0.0 6.7e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 CCD25340.1 - 1.2e-10 41.0 0.1 8e-08 31.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCD25340.1 - 2.6e-10 39.7 0.1 2.7e-06 26.4 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 CCD25340.1 - 1.9e-07 31.1 0.0 0.00018 21.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCD25340.1 - 0.0001 21.3 0.5 0.0072 15.2 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CCD25340.1 - 0.00075 19.4 0.3 0.003 17.5 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCD25340.1 - 0.00084 18.5 0.3 0.3 10.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 CCD25340.1 - 0.0014 17.1 0.2 0.0024 16.4 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 CCD25340.1 - 0.0032 16.5 0.0 0.47 9.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain GMC_oxred_N PF00732.14 CCD25340.1 - 0.0058 15.8 0.1 0.012 14.7 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox PF00070.22 CCD25340.1 - 0.018 15.4 0.0 0.06 13.7 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CCD25340.1 - 0.021 14.4 0.6 0.077 12.6 0.4 1.9 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 CCD25340.1 - 0.072 11.9 0.2 0.15 10.9 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Acyltransferase PF01553.16 CCD25341.1 - 1.1e-31 109.0 0.0 1.8e-31 108.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Trs65 PF12735.2 CCD25341.1 - 0.078 12.2 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 TFIIA PF03153.8 CCD25342.1 - 0.036 13.9 30.2 0.047 13.6 20.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 CCD25342.1 - 0.048 11.5 28.2 0.012 13.5 17.4 1.5 2 0 0 2 2 2 0 Nop14-like family PTPA PF03095.10 CCD25343.1 - 4.2e-112 374.1 0.0 5.3e-112 373.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein S-methyl_trans PF02574.11 CCD25344.1 - 1.4e-89 300.4 0.0 1.6e-89 300.2 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.20 CCD25344.1 - 0.021 14.3 0.2 0.36 10.3 0.0 2.4 2 0 0 2 2 2 0 Kelch motif zf-primase PF09329.6 CCD25347.1 - 2.1e-10 40.0 0.3 4.3e-10 39.0 0.2 1.6 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 CCD25347.1 - 0.014 15.2 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain FUSC PF04632.7 CCD25348.1 - 2.4 6.4 3.0 6.7 5.0 0.3 2.6 3 0 0 3 3 3 0 Fusaric acid resistance protein family ubiquitin PF00240.18 CCD25349.1 - 2.9e-34 116.2 0.9 4.3e-34 115.7 0.6 1.3 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CCD25349.1 - 5e-31 106.0 10.7 1.1e-30 104.9 7.4 1.6 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CCD25349.1 - 7.6e-18 63.9 0.4 1.2e-17 63.3 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCD25349.1 - 2e-05 24.7 0.2 6.7e-05 23.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCD25349.1 - 0.0062 16.2 0.0 0.0095 15.6 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCD25349.1 - 0.012 15.4 0.1 0.025 14.4 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCD25349.1 - 0.019 15.1 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain HATPase_c PF02518.21 CCD25350.1 - 6.8e-27 93.3 5.4 5.1e-26 90.5 3.8 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CCD25350.1 - 1e-26 93.1 0.3 2.6e-26 91.8 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 CCD25350.1 - 2.1e-10 40.4 0.1 6e-10 38.9 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 CCD25350.1 - 9.6e-06 25.6 0.1 0.045 13.9 0.0 2.7 2 0 0 2 2 2 2 HAMP domain Pantoate_ligase PF02569.10 CCD25351.1 - 6.2e-103 343.3 0.0 7e-103 343.2 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Ndc80_HEC PF03801.8 CCD25352.1 - 1.9e-51 173.6 3.3 1.9e-51 173.6 2.3 2.9 2 0 0 2 2 2 1 HEC/Ndc80p family Val_tRNA-synt_C PF10458.4 CCD25352.1 - 3.7 7.6 12.3 0.052 13.6 1.4 3.3 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm Helicase_C_3 PF13625.1 CCD25354.1 - 6.1e-25 87.4 0.0 1.6e-24 86.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD25354.1 - 6.9e-14 52.0 5.2 1e-13 51.5 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCD25354.1 - 2.9e-12 46.0 0.0 4.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCD25354.1 - 9.6e-11 41.3 0.2 3.4e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD25354.1 - 3e-07 30.0 0.0 6.3e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Abhydrolase_6 PF12697.2 CCD25355.1 - 4.2e-21 75.8 0.0 5.7e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD25355.1 - 3.2e-06 26.8 0.0 8.8e-06 25.4 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 CCD25355.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CCD25355.1 - 4.2e-05 23.3 0.0 0.00014 21.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCD25355.1 - 0.13 11.4 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Whi5 PF08528.6 CCD25356.1 - 6.1e-08 32.0 0.4 1.1e-07 31.2 0.3 1.5 1 0 0 1 1 1 1 Whi5 like SR-25 PF10500.4 CCD25356.1 - 0.35 10.3 35.7 0.43 10.0 10.8 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein LIM PF00412.17 CCD25357.1 - 1.9e-06 27.8 21.3 3.4e-06 27.0 7.2 3.8 3 1 0 3 3 3 2 LIM domain DUF2688 PF10892.3 CCD25357.1 - 0.013 15.1 0.6 0.031 13.9 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2688) CP12 PF02672.10 CCD25357.1 - 0.022 15.1 0.4 1.8 9.0 0.1 2.6 2 0 0 2 2 2 0 CP12 domain DUF3336 PF11815.3 CCD25358.1 - 2.1e-39 134.3 4.3 2.1e-39 134.3 3.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CCD25358.1 - 2.3e-29 102.8 0.0 4.3e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_11 PF13414.1 CCD25359.1 - 4.4e-10 39.0 3.9 0.0037 16.8 0.0 3.4 2 1 1 3 3 3 3 TPR repeat TPR_1 PF00515.23 CCD25359.1 - 1.1e-09 37.4 5.1 0.001 18.5 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCD25359.1 - 1.2e-09 37.3 3.1 0.00043 19.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCD25359.1 - 8.5e-08 32.0 0.7 0.002 18.0 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box PF00646.28 CCD25359.1 - 2.4e-05 23.8 0.0 7.7e-05 22.2 0.0 1.9 1 0 0 1 1 1 1 F-box domain TPR_8 PF13181.1 CCD25359.1 - 3e-05 23.4 4.3 0.0012 18.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat LRR_4 PF12799.2 CCD25359.1 - 0.00033 20.2 19.7 0.0031 17.0 0.7 6.3 5 2 0 5 5 5 2 Leucine Rich repeats (2 copies) TPR_7 PF13176.1 CCD25359.1 - 0.0043 16.7 1.5 0.1 12.4 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat F-box-like PF12937.2 CCD25359.1 - 0.0044 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 CCD25359.1 - 0.0049 16.8 9.4 53 4.6 0.1 7.0 6 1 0 6 6 5 0 Leucine rich repeat Apc3 PF12895.2 CCD25359.1 - 0.017 15.2 4.4 3.1 8.0 0.1 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 LRR_6 PF13516.1 CCD25359.1 - 0.071 13.2 13.8 18 5.8 0.0 6.5 6 0 0 6 6 5 0 Leucine Rich repeat TPR_16 PF13432.1 CCD25359.1 - 0.13 12.9 0.1 15 6.4 0.0 2.7 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCD25359.1 - 0.19 12.2 0.5 1.8 9.1 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SR-25 PF10500.4 CCD25359.1 - 0.26 10.7 7.9 1.4 8.3 1.1 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Zip PF02535.17 CCD25360.1 - 1.1e-44 152.7 8.9 2.3e-42 145.1 6.1 2.2 1 1 0 1 1 1 1 ZIP Zinc transporter DUF1628 PF07790.6 CCD25360.1 - 0.63 10.8 4.1 1.1 10.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1628) U3_snoRNA_assoc PF08297.6 CCD25361.1 - 2e-17 63.1 6.3 2.2e-17 63.0 4.3 1.1 1 0 0 1 1 1 1 U3 snoRNA associated Kin17_mid PF10357.4 CCD25362.1 - 4.9e-37 126.4 9.2 4.9e-37 126.4 6.3 2.3 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 CCD25362.1 - 5.5e-07 29.5 3.3 5.5e-07 29.5 2.3 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCD25362.1 - 1.7e-05 24.8 2.8 6.2e-05 23.0 1.9 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCD25362.1 - 0.0024 17.9 3.6 0.0076 16.3 0.4 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CCD25362.1 - 0.034 14.4 1.7 0.087 13.2 1.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger UPF0728 PF15092.1 CCD25362.1 - 0.077 12.8 0.3 1.7 8.5 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 zf-C2H2 PF00096.21 CCD25362.1 - 0.11 12.8 2.7 0.28 11.6 1.9 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-DBF PF07535.7 CCD25362.1 - 0.71 9.5 4.0 3.4 7.4 0.2 2.5 2 0 0 2 2 2 0 DBF zinc finger AKAP95 PF04988.7 CCD25362.1 - 8.6 6.1 16.5 0.085 12.6 1.2 3.4 1 1 2 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) GTP_EFTU PF00009.22 CCD25363.1 - 2.3e-11 43.4 0.4 7.5e-11 41.8 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCD25363.1 - 3.3e-07 29.7 0.6 6.9e-07 28.6 0.4 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCD25363.1 - 2.8e-06 27.2 0.3 8e-06 25.7 0.2 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 CCD25363.1 - 0.0017 18.2 0.1 0.015 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CCD25363.1 - 0.0019 18.6 0.1 0.0081 16.6 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCD25363.1 - 0.01 15.0 0.8 2.1 7.5 0.0 2.7 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_14 PF13173.1 CCD25363.1 - 0.018 14.9 0.2 0.085 12.7 0.1 2.2 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CCD25363.1 - 0.021 15.6 0.0 0.052 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCD25363.1 - 0.051 12.9 0.0 0.75 9.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCD25363.1 - 0.055 13.0 0.0 0.19 11.2 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 CCD25363.1 - 0.45 10.8 0.0 0.45 10.8 0.0 3.1 4 0 0 4 4 4 0 AAA domain Thymidylat_synt PF00303.14 CCD25364.1 - 2e-117 390.9 0.0 2.3e-117 390.8 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Shugoshin_N PF07558.6 CCD25365.1 - 1.5e-10 40.6 10.7 1.5e-10 40.6 7.4 3.3 3 0 0 3 3 3 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 CCD25365.1 - 9.1e-10 37.8 6.8 9.1e-10 37.8 4.7 2.6 3 0 0 3 3 3 1 Shugoshin C terminus CHZ PF09649.5 CCD25365.1 - 0.0039 16.3 1.8 0.012 14.7 0.2 2.6 2 0 0 2 2 2 1 Histone chaperone domain CHZ TSC22 PF01166.13 CCD25365.1 - 0.02 14.8 5.1 0.02 14.8 3.5 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family Cu-oxidase_2 PF07731.9 CCD25365.1 - 0.078 12.4 2.7 0.18 11.2 0.8 2.5 1 1 0 1 1 1 0 Multicopper oxidase Brix PF04427.13 CCD25366.1 - 1.3e-35 122.8 1.2 1.8e-35 122.3 0.8 1.2 1 0 0 1 1 1 1 Brix domain RabGAP-TBC PF00566.13 CCD25367.1 - 1.1e-49 168.8 5.3 1.9e-49 168.0 2.9 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Vps5 PF09325.5 CCD25369.1 - 4.3e-63 212.7 11.6 4.3e-63 212.7 8.1 1.5 2 0 0 2 2 2 1 Vps5 C terminal like PX PF00787.19 CCD25369.1 - 7.4e-21 74.0 0.2 3.4e-20 71.9 0.0 2.2 2 0 0 2 2 2 1 PX domain CPSase_L_D3 PF02787.14 CCD25369.1 - 0.016 15.0 0.1 0.048 13.4 0.0 1.8 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Alg6_Alg8 PF03155.10 CCD25370.1 - 3.2e-159 530.7 41.7 3.7e-159 530.5 28.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family DUF2029 PF09594.5 CCD25370.1 - 0.0011 18.5 5.1 0.0011 18.5 3.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2029) Cytochrom_C1 PF02167.10 CCD25372.1 - 1.7e-83 279.6 0.0 2.1e-83 279.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CCD25372.1 - 0.00037 20.5 0.1 0.00089 19.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CCD25372.1 - 0.0024 18.6 0.2 0.0079 17.0 0.1 1.9 1 1 0 1 1 1 1 Cytochrome c PHD PF00628.24 CCD25373.1 - 2e-08 33.7 7.3 3.3e-08 33.0 5.0 1.3 1 0 0 1 1 1 1 PHD-finger Pkinase PF00069.20 CCD25375.1 - 8.7e-53 179.1 0.1 1.1e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25375.1 - 5.8e-17 61.6 0.1 9.2e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCD25375.1 - 2.6e-07 30.6 0.0 6.5e-07 29.3 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCD25375.1 - 0.00045 19.8 0.1 0.00086 18.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase AcetylCoA_hydro PF02550.10 CCD25375.1 - 0.073 12.8 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase N-terminal domain Vma12 PF11712.3 CCD25376.1 - 0.036 13.7 0.6 0.057 13.1 0.4 1.4 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase RTA1 PF04479.8 CCD25377.1 - 6.5e-85 284.1 10.9 8.7e-85 283.7 7.5 1.2 1 0 0 1 1 1 1 RTA1 like protein zf-DHHC PF01529.15 CCD25377.1 - 1.1 8.6 11.3 0.88 8.9 0.9 2.8 2 1 0 2 2 2 0 DHHC palmitoyltransferase Nro1 PF12753.2 CCD25378.1 - 2.4e-132 441.6 20.6 2.8e-132 441.5 14.3 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 FAST_1 PF06743.10 CCD25378.1 - 0.00032 20.3 0.2 0.0012 18.5 0.1 1.9 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 1 TPR_19 PF14559.1 CCD25378.1 - 0.013 15.7 1.7 1.9 8.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF910 PF06014.6 CCD25378.1 - 0.032 14.1 0.4 4 7.4 0.1 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF910) Dynamin_N PF00350.18 CCD25378.1 - 3.2 7.5 6.7 0.53 10.0 0.5 2.5 3 1 0 3 3 3 0 Dynamin family zf-AN1 PF01428.11 CCD25379.1 - 2.6e-08 33.5 8.3 5.1e-08 32.6 5.8 1.5 1 0 0 1 1 1 1 AN1-like Zinc finger DUF612 PF04747.7 CCD25379.1 - 0.0054 15.7 5.5 0.0054 15.7 3.8 1.4 2 0 0 2 2 2 1 Protein of unknown function, DUF612 Flavoprotein PF02441.14 CCD25380.1 - 1.4e-41 141.1 0.1 3.4e-41 139.9 0.1 1.7 1 0 0 1 1 1 1 Flavoprotein CDC45 PF02724.9 CCD25380.1 - 0.22 9.5 18.3 0.34 8.8 12.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 CCD25380.1 - 0.96 8.7 18.0 0.043 13.1 8.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) MAP65_ASE1 PF03999.7 CCD25381.1 - 4.9e-69 233.5 43.9 4.9e-69 233.5 30.4 2.0 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) YlqD PF11068.3 CCD25381.1 - 0.0084 16.1 4.7 0.0084 16.1 3.3 3.9 3 1 0 4 4 4 2 YlqD protein RVT_1 PF00078.22 CCD25382.1 - 2.3e-24 85.9 0.2 5.7e-24 84.6 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCD25382.1 - 1.8e-18 66.7 0.1 7.5e-18 64.7 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain Asp_protease_2 PF13650.1 CCD25382.1 - 1.7e-10 41.2 0.0 3.8e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CCD25382.1 - 1.9e-06 27.5 0.0 3.9e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CCD25382.1 - 8.9e-06 25.6 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CCD25382.1 - 1e-05 25.3 0.3 6.4e-05 22.8 0.1 2.4 3 0 0 3 3 3 1 Retroviral aspartyl protease zf-CCHC PF00098.18 CCD25383.1 - 7.1e-06 25.7 2.4 1.3e-05 24.9 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CCD25383.1 - 0.0016 18.0 1.1 0.0044 16.6 0.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CCD25383.1 - 0.12 12.1 1.8 0.19 11.5 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF2340 PF10209.4 CCD25384.1 - 1.3e-53 180.3 5.0 1.5e-53 180.1 3.5 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DUF676 PF05057.9 CCD25385.1 - 4.1e-44 150.4 0.0 6.7e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CCD25385.1 - 0.0015 18.1 0.0 0.0044 16.6 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CCD25385.1 - 0.038 13.7 0.0 0.2 11.4 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.4 CCD25385.1 - 0.05 12.4 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) XRN_N PF03159.13 CCD25387.1 - 7.9e-108 359.2 1.7 3.9e-107 357.0 0.0 2.3 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus PMSI1 PF15322.1 CCD25387.1 - 5.9 5.8 8.8 16 4.4 6.1 1.8 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative DEAD PF00270.24 CCD25389.1 - 2.7e-35 121.3 0.6 5.3e-35 120.4 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD25389.1 - 5.8e-27 93.3 0.0 1.1e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD25389.1 - 0.00019 21.2 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CCD25389.1 - 0.00045 20.2 0.0 0.0043 17.0 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain CMS1 PF14617.1 CCD25389.1 - 0.058 12.4 0.5 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Pap_E4 PF02711.9 CCD25391.1 - 0.14 12.9 0.4 1.5 9.6 0.0 2.0 2 0 0 2 2 2 0 E4 protein Herpes_LMP1 PF05297.6 CCD25391.1 - 2.2 7.1 4.7 0.23 10.3 0.4 1.4 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) Kri1_C PF12936.2 CCD25392.1 - 0.031 14.2 0.4 0.031 14.2 0.3 2.1 2 1 0 2 2 2 0 KRI1-like family C-terminal CUE PF02845.11 CCD25393.1 - 2.3e-10 39.7 0.0 4.1e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain Lactamase_B PF00753.22 CCD25394.1 - 1.7e-15 57.2 0.0 4.1e-15 55.9 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCD25394.1 - 6.6e-06 25.8 0.1 9.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Gp-FAR-1 PF05823.7 CCD25394.1 - 0.0043 17.0 0.1 0.029 14.3 0.1 2.0 1 1 1 2 2 2 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Lactamase_B_3 PF13483.1 CCD25394.1 - 0.0061 16.2 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CK_II_beta PF01214.13 CCD25395.1 - 2.5e-73 245.4 0.1 3.1e-73 245.2 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit Rad4 PF03835.10 CCD25395.1 - 0.15 11.4 0.2 0.4 10.0 0.1 1.7 2 0 0 2 2 2 0 Rad4 transglutaminase-like domain Hira PF07569.6 CCD25396.1 - 7.3e-78 260.7 0.8 4.1e-77 258.2 0.3 2.4 2 0 0 2 2 2 1 TUP1-like enhancer of split FAD_binding_6 PF00970.19 CCD25397.1 - 3.8e-07 30.1 0.0 7.1e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain Syntaxin_2 PF14523.1 CCD25398.1 - 3.3e-19 68.8 12.5 3.3e-19 68.8 8.7 2.7 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 CCD25398.1 - 1e-17 63.5 6.2 1e-17 63.5 4.3 2.5 3 0 0 3 3 3 1 SNARE domain DUF1409 PF07197.7 CCD25398.1 - 0.01 15.8 0.1 0.056 13.5 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) DUF4370 PF14290.1 CCD25398.1 - 0.036 13.5 0.2 0.073 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) DUF2951 PF11166.3 CCD25398.1 - 0.037 13.8 0.9 0.037 13.8 0.6 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2951) MtrB PF05440.7 CCD25398.1 - 0.05 13.6 0.3 0.64 10.1 0.0 2.4 2 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B EST1 PF10374.4 CCD25398.1 - 0.19 11.7 8.6 0.43 10.5 3.9 2.5 2 1 0 2 2 2 0 Telomerase activating protein Est1 V-SNARE PF05008.10 CCD25398.1 - 0.25 11.5 13.4 0.085 13.0 0.8 3.8 2 2 2 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Cag12 PF13117.1 CCD25398.1 - 0.26 11.1 4.9 0.12 12.3 0.7 2.3 2 1 0 2 2 2 0 Cag pathogenicity island protein Cag12 SRP1_TIP1 PF00660.12 CCD25398.1 - 0.43 10.4 2.3 6 6.7 0.1 2.5 2 0 0 2 2 2 0 Seripauperin and TIP1 family DUF1664 PF07889.7 CCD25398.1 - 0.63 9.8 14.3 0.39 10.5 1.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.16 CCD25398.1 - 0.87 9.2 9.1 0.064 12.8 1.7 2.5 2 1 1 3 3 3 0 Synaptobrevin GLE1 PF07817.8 CCD25398.1 - 0.89 8.4 13.5 0.039 12.8 0.7 2.7 2 1 0 2 2 2 0 GLE1-like protein MCPsignal PF00015.16 CCD25398.1 - 1.3 8.5 13.7 0.6 9.6 2.6 2.5 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain CcoS PF03597.10 CCD25398.1 - 4.4 6.8 9.7 7.2 6.1 6.7 1.4 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type DUF2652 PF10851.3 CCD25400.1 - 0.055 13.4 0.7 0.11 12.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) zf-C2H2_4 PF13894.1 CCD25400.1 - 0.095 13.0 13.8 5.8 7.4 1.2 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCD25400.1 - 0.22 11.9 18.2 6.6 7.2 2.2 3.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type UNC45-central PF11701.3 CCD25401.1 - 3.3e-20 72.3 4.2 1e-19 70.7 0.0 3.6 4 0 0 4 4 4 1 Myosin-binding striated muscle assembly central ING PF12998.2 CCD25401.1 - 0.014 15.6 1.5 0.014 15.6 1.0 2.7 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Ank_2 PF12796.2 CCD25402.1 - 1.8e-43 146.7 0.1 2e-16 60.0 0.0 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CCD25402.1 - 2.3e-26 90.2 2.8 6.2e-07 28.9 0.0 6.4 5 1 1 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 CCD25402.1 - 2.8e-24 84.5 2.1 1.9e-09 37.4 0.1 6.3 1 1 5 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD25402.1 - 4.3e-23 79.0 1.5 0.0014 18.6 0.0 6.5 5 1 1 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 CCD25402.1 - 9.1e-21 73.8 7.0 7.6e-10 39.0 0.1 4.4 1 1 4 5 5 5 5 Ankyrin repeats (many copies) XPG_N PF00752.12 CCD25403.1 - 3.8e-29 100.9 0.0 1.1e-28 99.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCD25403.1 - 1.1e-20 73.5 0.0 3.5e-20 71.8 0.0 2.0 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 CCD25403.1 - 0.0054 16.2 0.5 0.014 14.9 0.0 1.9 2 0 0 2 2 2 1 XPG domain containing LON PF02190.11 CCD25403.1 - 0.047 13.3 2.2 0.096 12.3 0.1 2.3 2 0 0 2 2 2 0 ATP-dependent protease La (LON) domain HHH_2 PF12826.2 CCD25403.1 - 0.065 13.1 0.0 0.85 9.5 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif 5_3_exonuc PF01367.15 CCD25403.1 - 0.095 12.9 0.1 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Flavodoxin_NdrI PF07972.6 CCD25404.1 - 0.18 11.6 1.2 5.5 6.9 0.0 2.9 3 1 0 3 3 3 0 NrdI Flavodoxin like HLH PF00010.21 CCD25405.1 - 2.2e-19 68.8 1.9 1.3e-18 66.4 1.3 2.3 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain N1221 PF07923.8 CCD25407.1 - 0.071 11.9 0.7 0.076 11.8 0.5 1.0 1 0 0 1 1 1 0 N1221-like protein UMPH-1 PF05822.7 CCD25407.1 - 0.096 11.9 0.3 0.094 12.0 0.2 1.1 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) PalH PF08733.5 CCD25408.1 - 1.3e-50 172.2 19.7 1.7e-50 171.8 13.7 1.2 1 0 0 1 1 1 1 PalH/RIM21 Secretin_N_2 PF07655.8 CCD25408.1 - 2.4 8.5 18.2 0.067 13.5 4.1 2.7 3 0 0 3 3 3 0 Secretin N-terminal domain bZIP_1 PF00170.16 CCD25409.1 - 3e-09 36.7 8.4 3e-09 36.7 5.8 1.8 2 0 0 2 2 2 1 bZIP transcription factor HALZ PF02183.13 CCD25409.1 - 0.052 13.2 0.1 0.052 13.2 0.1 2.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper TPR_11 PF13414.1 CCD25410.1 - 7.3e-54 179.3 32.2 8.9e-17 60.5 0.0 6.3 5 1 1 6 6 6 6 TPR repeat TPR_1 PF00515.23 CCD25410.1 - 8.1e-47 155.0 21.2 3.5e-07 29.5 1.2 9.5 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 CCD25410.1 - 5.5e-39 128.9 21.7 1.4e-06 27.7 0.8 9.5 8 1 1 9 9 9 8 Tetratricopeptide repeat TPR_8 PF13181.1 CCD25410.1 - 2e-24 83.4 23.6 1.6e-05 24.3 1.1 9.5 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 CCD25410.1 - 2.8e-23 81.9 8.5 0.0025 18.4 0.0 6.5 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_12 PF13424.1 CCD25410.1 - 1.8e-22 79.0 17.3 2.2e-10 40.3 0.4 6.4 3 3 4 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCD25410.1 - 1.7e-21 74.7 5.6 0.067 13.8 0.0 9.7 5 3 5 10 10 9 5 Tetratricopeptide repeat TPR_7 PF13176.1 CCD25410.1 - 2.3e-14 51.9 9.4 0.0065 16.1 0.0 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCD25410.1 - 3e-14 51.9 12.5 0.019 15.1 0.0 7.8 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCD25410.1 - 5.6e-12 45.8 18.4 0.02 15.1 0.2 6.9 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_9 PF13371.1 CCD25410.1 - 6.4e-08 32.3 0.0 0.001 18.9 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCD25410.1 - 2.4e-05 24.4 17.6 1.8 9.1 0.0 8.0 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_20 PF14561.1 CCD25410.1 - 0.00011 22.2 10.6 0.035 14.2 0.2 5.1 3 3 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.1 CCD25410.1 - 0.00013 21.8 0.3 0.34 10.9 0.1 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3808 PF10300.4 CCD25410.1 - 0.00057 18.5 1.9 0.0015 17.1 0.0 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF3808) SHNi-TPR PF10516.4 CCD25410.1 - 0.024 13.9 8.2 15 4.9 0.1 6.5 7 0 0 7 7 7 0 SHNi-TPR PPR PF01535.15 CCD25410.1 - 0.15 12.0 2.0 84 3.4 0.0 5.2 7 0 0 7 7 7 0 PPR repeat Fis1_TPR_C PF14853.1 CCD25410.1 - 0.17 11.8 3.5 44 4.0 0.3 4.5 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat MAS20 PF02064.10 CCD25410.1 - 2.7 7.9 0.0 2.7 7.9 0.0 3.5 4 1 0 4 4 4 0 MAS20 protein import receptor WD40 PF00400.27 CCD25411.1 - 1.9e-10 40.1 1.5 2.5e-05 23.9 0.1 4.7 6 0 0 6 6 6 2 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCD25411.1 - 0.0024 16.6 0.3 0.2 10.3 0.0 2.8 3 0 0 3 3 3 1 Nup133 N terminal like eIF2A PF08662.6 CCD25411.1 - 0.014 15.1 0.1 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A Fcf1 PF04900.7 CCD25411.1 - 0.1 12.6 0.3 5.7 7.0 0.1 2.6 2 0 0 2 2 2 0 Fcf1 DUF2963 PF11178.3 CCD25411.1 - 0.51 9.7 2.4 0.88 9.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2963) SIR2 PF02146.12 CCD25412.1 - 4.7e-30 104.6 0.0 1e-15 57.9 0.0 2.3 2 0 0 2 2 2 2 Sir2 family DUF2256 PF10013.4 CCD25412.1 - 0.16 11.7 1.5 0.38 10.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Allantoicase PF03561.10 CCD25414.1 - 8.5e-45 151.9 2.8 1.3e-40 138.3 0.2 2.1 2 0 0 2 2 2 2 Allantoicase repeat Transp_cyt_pur PF02133.10 CCD25415.1 - 6.8e-174 578.5 40.8 8.4e-174 578.2 28.3 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Complex1_LYR_2 PF13233.1 CCD25415.1 - 0.11 13.0 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Complex1_LYR-like Amidohydro_1 PF01979.15 CCD25416.1 - 2.1e-31 109.7 0.1 3.5e-30 105.7 0.0 2.1 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CCD25416.1 - 4e-25 89.3 0.0 4.9e-13 49.7 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 CCD25416.1 - 4.1e-09 36.1 0.1 1.3e-08 34.5 0.1 1.9 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 CCD25416.1 - 8e-08 31.9 0.0 0.00013 21.3 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Asp_Glu_race PF01177.17 CCD25417.1 - 8.7e-20 71.5 0.0 1e-19 71.3 0.0 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Malate_synthase PF01274.17 CCD25418.1 - 7.5e-215 713.8 0.0 9.1e-215 713.5 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 CCD25418.1 - 0.0065 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Ureidogly_hydro PF04115.7 CCD25419.1 - 5.5e-42 142.9 0.0 6.1e-42 142.7 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase CAMSAP_CH PF11971.3 CCD25419.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 CAMSAP CH domain Cpn10 PF00166.16 CCD25420.1 - 1.6e-26 92.0 0.2 1.8e-26 91.9 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF4537 PF15057.1 CCD25421.1 - 0.095 12.4 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4537) DOPA_dioxygen PF08883.6 CCD25422.1 - 0.059 13.4 0.1 0.2 11.7 0.1 1.9 1 0 0 1 1 1 0 Dopa 4,5-dioxygenase family Acetyltransf_1 PF00583.19 CCD25423.1 - 6.5e-14 51.7 0.0 9e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCD25423.1 - 1.9e-05 24.2 0.1 3.7e-05 23.3 0.0 1.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 CCD25423.1 - 7.2e-05 22.8 0.1 0.00019 21.5 0.1 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCD25423.1 - 0.0012 18.7 0.1 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCD25423.1 - 0.0066 16.5 0.0 0.0099 16.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CCD25423.1 - 0.025 14.1 0.1 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCD25423.1 - 0.051 13.4 0.0 0.099 12.5 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Metallophos_2 PF12850.2 CCD25424.1 - 1.9e-14 53.8 0.0 2.8e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain tRNA-synt_2b PF00587.20 CCD25425.1 - 5.9e-17 61.7 0.0 1.2e-16 60.7 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CCD25425.1 - 0.00021 21.2 4.1 0.0004 20.3 2.8 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 CCD25425.1 - 0.00033 20.3 1.2 0.00058 19.5 0.9 1.4 1 0 0 1 1 1 1 IncA protein EzrA PF06160.7 CCD25425.1 - 0.0013 16.9 2.0 0.0019 16.4 1.4 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA 4HB_MCP_1 PF12729.2 CCD25425.1 - 0.0034 16.7 3.4 0.0061 15.9 2.4 1.3 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction Cut12 PF11500.3 CCD25425.1 - 0.0059 16.3 1.7 0.01 15.5 1.2 1.3 1 0 0 1 1 1 1 Spindle pole body formation-associated protein Baculo_PEP_C PF04513.7 CCD25425.1 - 0.0078 16.0 1.6 0.0078 16.0 1.1 1.9 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus FH2 PF02181.18 CCD25425.1 - 0.011 14.5 2.1 0.017 13.9 1.4 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain tRNA-synt_His PF13393.1 CCD25425.1 - 0.018 14.1 0.0 0.1 11.6 0.0 2.1 2 0 0 2 2 2 0 Histidyl-tRNA synthetase AAA_13 PF13166.1 CCD25425.1 - 0.036 12.5 5.7 0.05 12.0 3.9 1.1 1 0 0 1 1 1 0 AAA domain Occludin_ELL PF07303.8 CCD25425.1 - 0.058 14.1 0.4 0.14 12.9 0.3 1.6 1 0 0 1 1 1 0 Occludin homology domain DUF342 PF03961.8 CCD25425.1 - 0.085 11.2 2.2 0.13 10.6 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FliD_N PF02465.13 CCD25425.1 - 0.21 12.0 6.8 0.48 10.8 4.0 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ribosomal_L27e PF01777.13 CCD25426.1 - 5.3e-37 125.8 6.7 7.2e-37 125.3 4.6 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CCD25426.1 - 0.00026 20.6 1.5 0.0005 19.6 1.0 1.6 1 0 0 1 1 1 1 KOW motif DUF1512 PF07431.7 CCD25426.1 - 0.098 11.3 0.1 0.17 10.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DAO PF01266.19 CCD25427.1 - 1.1e-57 195.6 0.0 1e-35 123.3 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCD25427.1 - 1.4e-05 24.9 0.0 5.3e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF3439 PF11921.3 CCD25427.1 - 0.00044 19.9 1.0 0.00092 18.9 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Thi4 PF01946.12 CCD25427.1 - 0.0018 17.4 0.0 0.0038 16.3 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 CCD25427.1 - 0.048 13.7 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CCD25427.1 - 0.092 11.3 0.3 1.5 7.3 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FAM220 PF15487.1 CCD25427.1 - 0.63 9.3 4.7 1.1 8.6 3.3 1.3 1 0 0 1 1 1 0 FAM220 family DUF2457 PF10446.4 CCD25427.1 - 0.9 8.1 15.6 1.4 7.5 10.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Cwf_Cwc_15 PF04889.7 CCD25427.1 - 1.2 8.8 21.0 0.14 11.8 11.2 1.7 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Nucleoplasmin PF03066.10 CCD25427.1 - 3.8 7.0 9.1 8.5 5.8 6.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin BUD22 PF09073.5 CCD25427.1 - 4.5 6.2 15.2 6.5 5.7 10.5 1.1 1 0 0 1 1 1 0 BUD22 Sod_Fe_C PF02777.13 CCD25428.1 - 4.3e-36 122.9 0.6 7.7e-36 122.1 0.4 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CCD25428.1 - 3.8e-26 91.1 0.5 8e-26 90.1 0.4 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.2 CCD25428.1 - 0.0038 17.0 0.0 0.0078 16.0 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif p450 PF00067.17 CCD25429.1 - 4.5e-99 332.0 0.0 6.2e-99 331.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 LCAT PF02450.10 CCD25430.1 - 2.1e-128 428.6 0.6 3.8e-128 427.7 0.4 1.4 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_5 PF12695.2 CCD25430.1 - 0.0032 17.2 0.0 0.0066 16.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 CCD25430.1 - 0.01 15.1 0.0 0.023 14.0 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 2) DUF1749 PF08538.5 CCD25430.1 - 0.032 13.1 0.0 0.054 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 CCD25430.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Autophagy_N PF03986.8 CCD25431.1 - 4.8e-39 133.4 1.3 4.8e-39 133.4 0.9 2.2 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CCD25431.1 - 4e-22 78.1 0.1 1.1e-21 76.8 0.1 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CCD25431.1 - 3.4e-14 51.6 1.0 6e-14 50.8 0.7 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal VHS PF00790.14 CCD25432.1 - 2.4e-35 121.2 1.2 6.7e-35 119.7 0.0 2.3 2 1 1 3 3 3 1 VHS domain FYVE PF01363.16 CCD25432.1 - 3e-19 68.6 3.7 9.3e-19 67.0 2.6 1.8 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 CCD25432.1 - 2.5e-05 23.4 7.1 0.002 17.5 1.3 3.0 2 0 0 2 2 2 2 Ubiquitin interaction motif Cyclin_N PF00134.18 CCD25434.1 - 1.7e-36 124.5 2.1 2.9e-36 123.8 0.0 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Herpes_UL14 PF03580.9 CCD25434.1 - 0.14 11.9 2.9 0.36 10.6 2.0 1.7 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Scs3p PF10261.4 CCD25434.1 - 0.16 11.0 0.1 0.16 11.0 0.1 2.7 2 2 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM BBP1_C PF15272.1 CCD25435.1 - 4.3e-58 196.0 30.1 4.3e-58 196.0 20.9 3.5 3 1 0 4 4 4 2 Spindle pole body component BBP1, C-terminal BBP1_N PF15271.1 CCD25435.1 - 3.4e-44 150.7 11.6 3.4e-44 150.7 8.0 3.1 2 1 1 3 3 3 1 Spindle pole body component BBP1, Mps2-binding protein SAGA-Tad1 PF12767.2 CCD25436.1 - 1.2e-60 205.3 4.8 4.3e-60 203.4 3.3 1.9 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Fer2 PF00111.22 CCD25438.1 - 1.2e-12 47.4 1.6 1.5e-12 47.0 1.1 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain RabGAP-TBC PF00566.13 CCD25440.1 - 1.5e-49 168.4 0.4 1.5e-49 168.4 0.3 3.7 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Fungal_trans PF04082.13 CCD25441.1 - 5.4e-29 100.8 6.4 1.5e-28 99.3 4.5 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD25441.1 - 1.7e-07 31.0 18.0 2.9e-07 30.2 12.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 CCD25441.1 - 1.5e-05 24.8 0.9 3.7e-05 23.5 0.0 2.2 2 0 0 2 2 2 1 Gal4-like dimerisation domain DEAD PF00270.24 CCD25442.1 - 1e-22 80.3 0.0 2.1e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RQC PF09382.5 CCD25442.1 - 1e-21 76.6 0.4 1.6e-20 72.7 0.2 2.4 2 0 0 2 2 2 1 RQC domain Helicase_C PF00271.26 CCD25442.1 - 1.2e-19 69.9 2.3 9.2e-17 60.6 0.0 3.5 3 0 0 3 3 3 2 Helicase conserved C-terminal domain WD40 PF00400.27 CCD25443.1 - 5e-20 70.5 10.3 4.4e-07 29.5 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Rhomboid PF01694.17 CCD25445.1 - 6.9e-15 55.3 14.0 1.3e-14 54.4 9.7 1.4 1 0 0 1 1 1 1 Rhomboid family LpxB PF02684.10 CCD25445.1 - 0.093 11.3 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase DUF4229 PF14012.1 CCD25445.1 - 4.5 7.2 6.1 8.7 6.3 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF2075 PF09848.4 CCD25446.1 - 4.9e-97 325.0 0.8 6.1e-97 324.7 0.1 1.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CCD25446.1 - 5.7e-10 39.4 0.2 3e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 CCD25446.1 - 4.9e-05 23.2 0.0 0.0057 16.5 0.0 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_16 PF13191.1 CCD25446.1 - 0.00016 21.7 0.0 0.0003 20.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CCD25446.1 - 0.00021 21.1 0.1 0.0011 18.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 CCD25446.1 - 0.00032 20.8 0.0 0.00063 19.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCD25446.1 - 0.0045 16.6 0.0 0.01 15.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PIF1 PF05970.9 CCD25446.1 - 0.0065 15.4 0.0 0.014 14.3 0.0 1.6 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CCD25446.1 - 0.0098 15.4 0.0 0.082 12.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain Adeno_IVa2 PF02456.10 CCD25446.1 - 0.01 14.5 0.0 0.019 13.6 0.0 1.4 1 0 0 1 1 1 1 Adenovirus IVa2 protein VirE PF05272.6 CCD25446.1 - 0.021 14.3 0.0 0.062 12.7 0.0 1.8 2 0 0 2 2 2 0 Virulence-associated protein E T2SE PF00437.15 CCD25446.1 - 0.029 13.2 0.1 0.048 12.5 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DAP3 PF10236.4 CCD25446.1 - 0.047 12.6 0.1 0.15 10.9 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 UAA PF08449.6 CCD25447.1 - 1.4e-51 175.2 11.0 1.6e-51 175.0 7.6 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CCD25447.1 - 7.5e-09 35.4 9.3 1.3e-08 34.5 6.4 1.4 2 0 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CCD25447.1 - 3.8e-08 33.4 16.6 6.9e-08 32.5 8.6 2.2 2 0 0 2 2 2 1 EamA-like transporter family Nuc_sug_transp PF04142.10 CCD25447.1 - 0.00011 21.3 3.9 0.02 14.0 0.7 2.2 2 1 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 CCD25447.1 - 0.00014 22.0 11.5 0.0019 18.4 5.2 2.4 2 0 0 2 2 2 1 Multidrug resistance efflux transporter DUF912 PF06024.7 CCD25447.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1700 PF08006.6 CCD25447.1 - 0.53 9.5 8.8 0.99 8.6 6.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) BTP PF05232.7 CCD25447.1 - 8.6 6.1 9.3 0.18 11.5 0.6 2.4 2 0 0 2 2 2 0 Bacterial Transmembrane Pair family DUF3915 PF13054.1 CCD25448.1 - 0.27 11.1 2.7 0.23 11.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) RasGAP_C PF03836.10 CCD25449.1 - 9.6e-25 86.9 7.6 9.6e-25 86.9 5.3 2.7 3 0 0 3 3 3 1 RasGAP C-terminus RasGAP PF00616.14 CCD25449.1 - 6.1e-19 68.4 3.5 6.1e-19 68.4 2.4 3.2 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 CCD25449.1 - 1.1e-08 35.0 3.1 5.3e-08 32.8 0.0 3.6 3 0 0 3 3 3 1 Calponin homology (CH) domain IQ PF00612.22 CCD25449.1 - 3.1e-07 29.4 32.9 0.0051 16.3 0.3 9.8 10 0 0 10 10 10 3 IQ calmodulin-binding motif NPV_P10 PF05531.7 CCD25449.1 - 0.62 10.3 5.5 11 6.3 0.3 4.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TBCC PF07986.7 CCD25450.1 - 4.9e-07 29.1 4.0 2.4e-06 26.9 2.7 2.2 1 1 0 1 1 1 1 Tubulin binding cofactor C Ank_2 PF12796.2 CCD25451.1 - 3.7e-17 62.4 0.2 1.1e-16 60.9 0.1 1.8 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 CCD25451.1 - 2.6e-16 58.4 0.1 3.5e-07 29.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CCD25451.1 - 1.5e-15 56.8 0.1 7.5e-08 32.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCD25451.1 - 1.6e-15 57.1 0.1 6.6e-11 42.4 0.0 2.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD25451.1 - 3.2e-14 51.6 0.0 1.5e-05 24.8 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat PqqD PF05402.7 CCD25451.1 - 0.17 11.8 2.4 2.3 8.2 0.1 2.6 2 1 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) eIF-5_eIF-2B PF01873.12 CCD25452.1 - 5.5e-45 152.0 0.4 1.2e-44 150.9 0.1 1.6 2 0 0 2 2 2 1 Domain found in IF2B/IF5 IF2_N PF04760.10 CCD25452.1 - 0.024 14.2 0.7 0.12 12.0 0.0 2.6 3 1 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region TF_Zn_Ribbon PF08271.7 CCD25452.1 - 0.092 12.0 0.2 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Pkinase PF00069.20 CCD25453.1 - 1.7e-33 115.9 0.0 3.4e-24 85.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25453.1 - 1.4e-16 60.3 0.0 1e-10 41.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCD25453.1 - 0.069 12.0 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like TIP49 PF06068.8 CCD25454.1 - 2.6e-176 586.2 3.5 3.1e-176 585.9 2.5 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CCD25454.1 - 4.2e-08 32.5 2.3 0.00057 18.9 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CCD25454.1 - 5.8e-08 33.0 0.5 7.7e-05 22.9 0.1 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 CCD25454.1 - 7.4e-06 25.0 0.1 1.3e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 CCD25454.1 - 3.7e-05 23.8 0.0 0.00038 20.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCD25454.1 - 7.2e-05 22.9 0.2 0.13 12.3 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_14 PF13173.1 CCD25454.1 - 0.001 18.9 0.0 1.8 8.4 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_5 PF07728.9 CCD25454.1 - 0.0062 16.2 0.2 1.8 8.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCD25454.1 - 0.0068 15.5 0.9 0.14 11.2 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CCD25454.1 - 0.01 15.2 0.9 0.022 14.1 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CCD25454.1 - 0.023 14.6 0.1 0.058 13.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCD25454.1 - 0.032 13.9 0.1 0.069 12.9 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain Sipho_tail PF05709.6 CCD25454.1 - 0.05 12.7 0.1 0.1 11.6 0.0 1.5 1 0 0 1 1 1 0 Phage tail protein ATP-synt_C PF00137.16 CCD25455.1 - 1.5e-27 95.3 27.3 4.4e-15 55.3 3.1 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Mis14 PF08641.7 CCD25456.1 - 1.6e-25 89.8 7.5 1.6e-25 89.8 5.2 1.7 1 1 1 2 2 2 1 Kinetochore protein Mis14 like BLOC1_2 PF10046.4 CCD25456.1 - 0.026 14.6 7.0 0.47 10.6 0.2 3.0 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LAM_C PF12544.3 CCD25456.1 - 0.096 12.7 1.5 0.17 11.9 0.1 1.9 2 0 0 2 2 2 0 Lysine-2,3-aminomutase HATPase_c_4 PF13749.1 CCD25456.1 - 0.12 12.1 0.1 0.44 10.3 0.0 2.0 1 0 0 1 1 1 0 ATP-dependent DNA helicase recG C-terminal Syntaxin-6_N PF09177.6 CCD25456.1 - 0.23 11.8 6.9 0.9 9.9 2.9 2.8 2 2 0 2 2 2 0 Syntaxin 6, N-terminal DUF445 PF04286.7 CCD25456.1 - 0.68 9.3 5.1 1.1 8.7 3.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF445) IncA PF04156.9 CCD25456.1 - 8.4 5.9 9.3 82 2.7 6.5 2.4 1 1 0 1 1 1 0 IncA protein SNARE PF05739.14 CCD25457.1 - 1.1e-15 57.0 7.0 1.1e-15 57.0 4.9 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CCD25457.1 - 0.00012 22.2 22.8 0.00022 21.3 5.3 2.7 2 1 0 2 2 2 2 Syntaxin Synaptobrevin PF00957.16 CCD25457.1 - 0.00019 20.9 10.5 0.00026 20.5 1.4 2.7 2 0 0 2 2 2 1 Synaptobrevin Rifin_STEVOR PF02009.11 CCD25457.1 - 0.00096 18.8 5.9 0.00096 18.8 4.1 1.9 1 1 0 2 2 2 1 Rifin/stevor family DUF2562 PF10814.3 CCD25457.1 - 0.0059 16.5 3.4 0.0061 16.5 1.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2562) T2SF PF00482.18 CCD25457.1 - 0.0066 16.3 0.1 0.015 15.2 0.1 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F HupH_C PF04809.8 CCD25457.1 - 0.033 13.9 0.1 0.065 12.9 0.1 1.5 1 0 0 1 1 1 0 HupH hydrogenase expression protein, C-terminal conserved region PilJ PF13675.1 CCD25457.1 - 0.077 13.3 13.6 0.19 12.0 3.0 2.7 1 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term COG5 PF10392.4 CCD25457.1 - 0.14 12.1 10.6 0.74 9.7 0.5 2.7 2 1 0 2 2 2 0 Golgi transport complex subunit 5 DUF3753 PF12575.3 CCD25457.1 - 0.23 11.3 1.5 4 7.3 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) DUF848 PF05852.6 CCD25457.1 - 0.62 9.9 15.0 1.8 8.4 2.6 2.7 2 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) FdhE PF04216.7 CCD25457.1 - 0.67 9.6 3.7 0.31 10.7 0.4 1.8 1 1 1 2 2 2 0 Protein involved in formate dehydrogenase formation DUF1664 PF07889.7 CCD25457.1 - 1.9 8.3 13.6 0.37 10.6 2.8 3.4 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) SlyX PF04102.7 CCD25457.1 - 8.7 6.7 12.9 0.59 10.5 3.5 2.8 2 1 1 3 3 3 0 SlyX ketoacyl-synt PF00109.21 CCD25458.1 - 2.3e-17 63.3 0.0 4.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 CCD25458.1 - 4.9e-15 55.3 0.0 1.3e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 CCD25458.1 - 4.7e-12 45.8 0.0 1.2e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain zf-H2C2_2 PF13465.1 CCD25459.1 - 5.2e-09 35.9 3.8 5.2e-09 35.9 2.6 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCD25459.1 - 1.6e-08 34.4 9.1 0.0012 19.0 2.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD25459.1 - 2.2e-08 33.8 13.2 0.00049 20.2 1.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCD25459.1 - 0.0028 17.4 2.8 0.0079 16.0 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 CCD25459.1 - 0.072 13.3 0.4 0.072 13.3 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type mRNA_triPase PF02940.10 CCD25460.1 - 9.6e-60 201.9 0.1 9.6e-60 201.9 0.0 2.2 3 0 0 3 3 3 1 mRNA capping enzyme, beta chain Glycos_transf_2 PF00535.21 CCD25461.1 - 3.1e-23 82.2 0.0 6e-23 81.3 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CCD25461.1 - 2.5e-07 30.7 0.0 5.6e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CCD25461.1 - 1.4e-05 24.3 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CCD25461.1 - 0.072 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Cation_efflux PF01545.16 CCD25462.1 - 2.2e-44 151.6 5.1 3e-44 151.2 3.6 1.2 1 0 0 1 1 1 1 Cation efflux family UPF0061 PF02696.9 CCD25464.1 - 2.6e-159 530.6 0.0 3e-159 530.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family TRP PF06011.7 CCD25465.1 - 4.9e-153 509.8 33.9 7.4e-153 509.2 23.5 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCD25465.1 - 2.8e-43 147.3 1.2 5e-43 146.5 0.8 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 CCD25465.1 - 0.0055 16.9 0.1 0.0095 16.1 0.1 1.4 1 0 0 1 1 1 1 ML domain Ribosomal_L1 PF00687.16 CCD25466.1 - 1.1e-44 152.3 1.8 1.4e-44 152.0 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cyclin PF08613.6 CCD25467.1 - 3.7e-15 56.6 2.1 8e-15 55.5 1.5 1.7 1 1 0 1 1 1 1 Cyclin Arf PF00025.16 CCD25468.1 - 4.1e-64 215.0 0.0 4.6e-64 214.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CCD25468.1 - 1.7e-08 33.5 1.6 2.2e-05 23.3 0.1 2.7 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CCD25468.1 - 3.8e-08 33.8 0.0 5.4e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CCD25468.1 - 4.1e-08 32.7 0.0 4.7e-08 32.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCD25468.1 - 1.4e-07 30.9 0.0 1.7e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CCD25468.1 - 6.3e-06 26.1 0.0 8.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCD25468.1 - 9.1e-05 21.6 0.0 9.9e-05 21.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCD25468.1 - 0.00095 18.6 0.1 0.016 14.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CCD25468.1 - 0.075 12.5 0.0 0.16 11.4 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Tegument_dsDNA PF12818.2 CCD25468.1 - 0.11 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein DUF663 PF04950.7 CCD25469.1 - 1.4e-105 352.5 0.1 1.4e-105 352.5 0.0 2.9 4 0 0 4 4 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CCD25469.1 - 4.6e-29 99.7 0.0 1.4e-28 98.2 0.0 1.9 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CCD25469.1 - 3.3e-07 29.9 3.8 4.3e-06 26.2 0.0 3.0 2 1 0 2 2 1 1 Elongation factor Tu GTP binding domain AAA PF00004.24 CCD25469.1 - 7.8e-06 26.1 0.2 2.9e-05 24.2 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 CCD25469.1 - 0.00012 21.7 0.0 0.00038 20.1 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CCD25469.1 - 0.00018 21.4 0.0 0.00071 19.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCD25469.1 - 0.00027 20.6 0.1 0.00066 19.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CCD25469.1 - 0.00029 20.8 0.0 0.00094 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCD25469.1 - 0.001 19.1 0.1 0.0081 16.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CCD25469.1 - 0.0016 18.9 1.3 0.0035 17.8 0.0 2.4 3 0 0 3 3 1 1 Miro-like protein AAA_17 PF13207.1 CCD25469.1 - 0.0055 17.5 0.0 0.0055 17.5 0.0 4.0 4 2 0 4 4 2 1 AAA domain RNA_helicase PF00910.17 CCD25469.1 - 0.0057 16.8 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 CCD25469.1 - 0.0063 16.1 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.18 CCD25469.1 - 0.0069 16.3 0.0 0.023 14.6 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 CCD25469.1 - 0.012 15.1 0.1 0.024 14.0 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 CCD25469.1 - 0.012 15.5 0.1 0.041 13.8 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCD25469.1 - 0.017 14.8 0.0 0.049 13.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CCD25469.1 - 0.017 14.8 0.3 0.039 13.6 0.2 1.6 1 0 0 1 1 1 0 NTPase AAA_25 PF13481.1 CCD25469.1 - 0.017 14.5 0.0 0.047 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CCD25469.1 - 0.021 14.4 0.0 0.021 14.4 0.0 3.5 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 CCD25469.1 - 0.021 15.1 0.0 0.021 15.1 0.0 2.7 3 0 0 3 3 2 0 ABC transporter AAA_18 PF13238.1 CCD25469.1 - 0.033 14.4 0.0 0.033 14.4 0.0 4.5 4 2 0 4 4 3 0 AAA domain Bac_rhodopsin PF01036.13 CCD25470.1 - 1e-55 188.4 16.7 1.2e-55 188.2 11.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 CCD25470.1 - 0.48 9.8 14.9 0.35 10.2 3.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) WAC_Acf1_DNA_bd PF10537.4 CCD25471.1 - 7.3e-28 96.7 2.1 2.5e-27 95.0 1.4 2.0 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CCD25471.1 - 6.9e-12 44.9 0.2 8.3e-11 41.4 0.0 2.7 3 0 0 3 3 3 1 DDT domain WHIM2 PF15613.1 CCD25471.1 - 6e-09 35.4 1.1 1.6e-08 34.1 0.7 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 CCD25471.1 - 0.00011 21.8 0.4 0.00011 21.8 0.3 2.1 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 3 Ubiq_cyt_C_chap PF03981.7 CCD25472.1 - 2.9e-43 147.1 1.0 4.4e-43 146.5 0.7 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone Glycoprotein PF03409.10 CCD25472.1 - 0.035 12.8 0.0 0.052 12.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein HK PF02110.10 CCD25473.1 - 3.6e-85 285.0 0.3 5e-85 284.5 0.2 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 CCD25473.1 - 3.1e-58 195.8 0.0 4.8e-58 195.2 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI MRF_C1 PF13887.1 CCD25473.1 - 0.12 11.3 0.0 0.29 10.1 0.0 1.6 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 LRR_9 PF14580.1 CCD25474.1 - 5.1e-16 58.7 0.3 9.1e-16 57.9 0.2 1.5 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CCD25474.1 - 1.2e-08 34.3 20.9 3.1e-07 29.8 1.8 3.3 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCD25474.1 - 0.00049 19.7 14.6 0.0078 15.9 4.3 3.3 1 1 3 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CCD25474.1 - 0.0021 17.8 16.8 2.2 8.6 0.3 4.9 4 0 0 4 4 4 3 Leucine Rich Repeat LRR_7 PF13504.1 CCD25474.1 - 0.92 9.9 17.3 1.9 9.0 0.2 5.2 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.1 CCD25474.1 - 2.1 8.6 20.5 1.8 8.8 0.6 5.5 4 1 1 5 5 5 0 Leucine Rich repeat Epimerase PF01370.16 CCD25475.1 - 3.1e-17 62.8 0.0 4.9e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCD25475.1 - 1.3e-12 47.0 0.0 1.7e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCD25475.1 - 3.3e-09 36.0 0.5 5.3e-08 32.0 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CCD25475.1 - 6.9e-09 35.9 0.1 1.2e-08 35.1 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCD25475.1 - 0.00016 21.0 0.1 0.064 12.4 0.0 2.3 2 0 0 2 2 2 2 NmrA-like family Polysacc_synt_2 PF02719.10 CCD25475.1 - 0.00026 19.9 0.1 0.00051 19.0 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 CCD25475.1 - 0.00034 20.3 0.0 0.00058 19.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 CCD25475.1 - 0.00043 20.2 0.0 0.0012 18.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCD25475.1 - 0.013 15.3 0.0 0.025 14.3 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase PseudoU_synth_1 PF01416.15 CCD25476.1 - 3.5e-22 78.7 0.0 3.1e-10 40.4 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.4 CCD25476.1 - 0.056 12.9 0.0 0.41 10.1 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) UPF0113 PF03657.8 CCD25477.1 - 3.3e-13 49.6 0.0 4.1e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 CCD25477.1 - 0.11 12.2 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 PUA domain TPR_12 PF13424.1 CCD25478.1 - 4.6e-10 39.2 5.0 2.7e-07 30.4 0.3 4.8 5 1 1 6 6 6 1 Tetratricopeptide repeat SRP72 PF08492.7 CCD25478.1 - 6.2e-07 29.6 6.5 6.2e-07 29.6 4.5 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 CCD25478.1 - 4.8e-05 23.4 12.8 0.65 10.1 0.6 5.6 5 1 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 CCD25478.1 - 7.6e-05 22.2 5.6 0.0064 16.1 0.2 4.0 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.1 CCD25478.1 - 0.0099 16.4 0.0 69 4.4 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCD25478.1 - 0.013 15.2 0.2 10 6.2 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCD25478.1 - 0.17 11.8 10.4 0.9 9.6 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCD25478.1 - 0.21 12.1 6.4 25 5.6 0.0 6.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCD25478.1 - 0.37 10.4 0.1 0.37 10.4 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 CCD25479.1 - 4.7e-73 245.5 0.0 6.6e-73 245.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25479.1 - 4.1e-47 160.4 0.0 5.5e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD25479.1 - 2.9e-08 33.0 0.0 2e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCD25479.1 - 0.0091 15.0 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD25479.1 - 0.022 14.5 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SET PF00856.23 CCD25480.1 - 0.0041 17.4 0.2 0.015 15.6 0.1 2.0 1 0 0 1 1 1 1 SET domain Reprolysin_4 PF13583.1 CCD25480.1 - 0.027 14.0 0.2 0.055 12.9 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Radical_SAM PF04055.16 CCD25481.1 - 6.7e-24 84.9 0.0 1.5e-23 83.7 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 CCD25481.1 - 5.4e-23 80.8 0.0 1.5e-22 79.4 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 CCD25481.1 - 1.5e-12 47.6 0.0 3.6e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin GDPD PF03009.12 CCD25482.1 - 1.1e-26 93.9 0.0 2.8e-26 92.5 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 CCD25482.1 - 0.00091 19.3 0.0 0.17 12.0 0.0 2.5 2 0 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family Pkinase PF00069.20 CCD25483.1 - 7.7e-40 136.6 0.0 7.7e-40 136.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25483.1 - 2.2e-14 53.1 0.0 4.4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCD25483.1 - 0.041 13.6 0.5 0.041 13.6 0.3 2.2 2 1 0 3 3 3 0 Phosphotransferase enzyme family DUF1682 PF07946.9 CCD25483.1 - 0.38 9.5 11.4 0.69 8.7 7.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Trypan_PARP PF05887.6 CCD25483.1 - 7 6.4 7.4 12 5.6 5.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.20 CCD25484.1 - 1.1e-70 237.7 0.0 1.7e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25484.1 - 1.5e-39 135.6 0.0 2.2e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD25484.1 - 1.8e-06 27.1 0.2 8.9e-06 24.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 CCD25484.1 - 0.04 13.2 0.1 0.04 13.2 0.1 1.9 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.6 CCD25484.1 - 0.047 12.5 0.0 0.08 11.7 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 CCD25484.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family AFT PF08731.6 CCD25485.1 - 2.2e-35 121.2 2.0 2.2e-35 121.2 1.4 3.6 3 1 0 3 3 3 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 CCD25485.1 - 0.00022 20.7 4.1 0.011 15.3 0.0 3.3 4 0 0 4 4 4 2 MuDR family transposase FAR1 PF03101.10 CCD25485.1 - 0.054 14.0 0.1 0.054 14.0 0.1 2.5 2 0 0 2 2 2 0 FAR1 DNA-binding domain HYLS1_C PF15311.1 CCD25486.1 - 0.019 15.1 0.1 0.049 13.8 0.1 1.7 1 0 0 1 1 1 0 Hydrolethalus syndrome protein 1 C-terminus Kelch_3 PF13415.1 CCD25486.1 - 0.05 13.7 0.1 0.17 12.1 0.0 1.9 1 0 0 1 1 1 0 Galactose oxidase, central domain CDK2AP PF09806.4 CCD25486.1 - 9.6 6.3 15.3 2.7 8.2 5.5 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DUF1421 PF07223.6 CCD25487.1 - 0.1 12.3 1.3 0.11 12.2 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) TLD PF07534.11 CCD25488.1 - 2.9e-29 101.8 0.4 2.9e-14 53.2 0.1 2.3 1 1 0 2 2 2 2 TLD SelP_N PF04592.9 CCD25488.1 - 3.2 7.0 7.0 0.27 10.5 1.5 1.6 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Adaptin_N PF01602.15 CCD25489.1 - 1.1e-109 367.1 16.6 1.5e-109 366.7 11.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCD25489.1 - 3.4e-09 36.7 0.9 3.4e-09 36.7 0.6 3.3 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCD25489.1 - 5.2e-06 26.6 0.0 0.012 15.9 0.0 4.4 3 2 1 4 4 4 1 HEAT repeats HEAT PF02985.17 CCD25489.1 - 0.00014 21.6 1.2 5.8 7.2 0.0 5.4 4 1 1 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 CCD25489.1 - 0.71 10.4 2.2 29 5.3 0.0 4.2 4 2 2 6 6 6 0 HEAT-like repeat Peptidase_S49_N PF08496.5 CCD25489.1 - 2.6 7.8 7.8 6.1 6.6 5.4 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rad9 PF04139.8 CCD25490.1 - 3.8e-11 42.5 1.5 1.4e-05 24.3 0.1 2.3 2 0 0 2 2 2 2 Rad9 RRM_1 PF00076.17 CCD25491.1 - 1.2e-37 127.3 0.2 1.1e-17 63.3 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD25491.1 - 6.6e-28 96.4 0.2 3.7e-10 39.6 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD25491.1 - 7.7e-19 67.2 0.0 4.8e-08 32.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCD25491.1 - 0.00067 19.3 0.0 0.026 14.2 0.0 2.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CCD25491.1 - 0.0015 18.3 0.1 0.0072 16.1 0.0 2.0 2 0 0 2 2 2 1 RNA binding motif HlyIII PF03006.15 CCD25493.1 - 3.5e-49 167.1 23.6 4.2e-49 166.9 16.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF2076 PF09849.4 CCD25494.1 - 6e-06 26.4 7.5 7.5e-06 26.1 5.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CCD25494.1 - 0.00032 20.5 4.2 0.00049 19.9 2.9 1.3 1 0 0 1 1 1 1 CHCH domain Nucleoporin_FG PF13634.1 CCD25494.1 - 4.6 7.4 17.3 7.7 6.7 12.0 1.4 1 1 0 1 1 1 0 Nucleoporin FG repeat region NAD_binding_7 PF13241.1 CCD25495.1 - 2.6e-22 79.0 0.0 3.8e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CCD25495.1 - 4.3e-12 45.1 0.0 1.1e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CCD25495.1 - 8.1e-10 37.5 0.0 1.6e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central MyTH4 PF00784.12 CCD25495.1 - 0.011 15.6 0.0 0.21 11.5 0.0 2.4 2 0 0 2 2 2 0 MyTH4 domain Pyr_redox_3 PF13738.1 CCD25495.1 - 0.013 15.5 0.1 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase CBS PF00571.23 CCD25496.1 - 9.3e-24 82.9 0.3 2.5e-06 27.1 0.0 5.3 5 0 0 5 5 5 5 CBS domain CPSase_L_D2 PF02786.12 CCD25497.1 - 1.1e-83 279.6 0.1 1.8e-83 278.9 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CCD25497.1 - 3.3e-65 219.2 0.0 5.3e-65 218.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_C PF02785.14 CCD25497.1 - 7.3e-31 106.3 0.0 4.4e-30 103.8 0.0 2.3 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CCD25497.1 - 1.2e-28 100.3 0.0 2.7e-28 99.2 0.0 1.6 1 0 0 1 1 1 1 HMGL-like CPSase_L_chain PF00289.17 CCD25497.1 - 1e-24 86.7 0.0 2.5e-24 85.5 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 CCD25497.1 - 2.4e-19 68.7 4.4 2.4e-19 68.7 3.0 2.0 2 0 0 2 2 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CCD25497.1 - 1.3e-17 63.6 0.0 1e-16 60.6 0.0 2.4 3 1 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CCD25497.1 - 5.2e-15 55.6 0.1 9.5e-15 54.8 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCD25497.1 - 3.6e-08 33.0 0.0 6.8e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CCD25497.1 - 3.7e-08 32.9 0.0 7.1e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CCD25497.1 - 5.9e-08 32.2 3.2 0.00075 19.1 0.2 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 CCD25497.1 - 5.7e-07 29.5 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 CCD25497.1 - 0.00019 21.7 1.4 0.31 11.4 0.1 3.2 3 0 0 3 3 3 2 HlyD family secretion protein RimK PF08443.6 CCD25497.1 - 0.00021 20.8 0.0 0.00071 19.1 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD PF00529.15 CCD25497.1 - 0.00092 18.5 2.0 0.21 10.8 0.1 2.6 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_2 PF12700.2 CCD25497.1 - 0.0056 15.8 1.2 1.5 7.8 0.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein NQRA PF05896.6 CCD25497.1 - 0.0075 15.4 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.1 CCD25497.1 - 0.023 14.4 1.1 0.15 11.8 0.5 2.6 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 CCD25497.1 - 0.1 12.2 0.8 0.29 10.8 0.6 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein SIR2 PF02146.12 CCD25497.1 - 0.2 11.3 0.0 1.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Sir2 family APG12 PF04110.8 CCD25498.1 - 5.6e-30 103.3 0.0 8.2e-30 102.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Kinetochor_Ybp2 PF08568.5 CCD25499.1 - 7.6e-128 427.4 11.8 9.1e-128 427.2 8.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin HUN PF08729.5 CCD25500.1 - 3.8e-13 49.0 0.3 3.8e-13 49.0 0.2 2.3 1 1 1 2 2 2 1 HPC2 and ubinuclein domain Acatn PF13000.2 CCD25501.1 - 2.6e-238 791.9 14.9 3e-238 791.8 10.3 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 Transket_pyr PF02779.19 CCD25502.1 - 3.2e-48 163.5 0.0 9.7e-48 161.9 0.0 1.7 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCD25502.1 - 1.4e-36 125.1 0.1 3e-36 124.0 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain AMP-binding PF00501.23 CCD25503.1 - 1.9e-72 243.9 0.0 2.5e-72 243.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCD25503.1 - 1.2e-14 55.0 0.1 3.2e-14 53.6 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Tyr-DNA_phospho PF06087.7 CCD25504.1 - 8.8e-94 314.6 11.0 1.2e-93 314.1 7.6 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Methyltransf_11 PF08241.7 CCD25505.1 - 0.00012 22.4 0.0 0.0022 18.4 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain AAA_2 PF07724.9 CCD25506.1 - 5.2e-36 124.1 0.2 1.1e-35 123.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CCD25506.1 - 1.4e-14 54.4 0.1 2.7e-14 53.4 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CCD25506.1 - 3.5e-09 36.4 0.4 2.2e-08 33.8 0.0 2.5 2 1 1 3 3 3 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CCD25506.1 - 1.3e-06 28.1 0.0 3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCD25506.1 - 1e-05 25.6 0.3 0.00014 22.0 0.1 2.7 2 2 1 3 3 1 1 AAA domain AAA_16 PF13191.1 CCD25506.1 - 1.6e-05 24.9 0.4 0.00015 21.8 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CCD25506.1 - 2.2e-05 25.2 1.2 0.00017 22.3 0.0 2.7 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCD25506.1 - 6.9e-05 22.0 0.0 0.0046 16.1 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCD25506.1 - 0.00053 19.4 0.0 0.085 12.3 0.0 2.7 3 0 0 3 3 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CCD25506.1 - 0.0022 17.4 0.0 0.0045 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCD25506.1 - 0.0034 17.2 0.1 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CCD25506.1 - 0.0043 16.6 0.0 0.019 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCD25506.1 - 0.0045 16.0 0.0 0.014 14.4 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DEAD PF00270.24 CCD25506.1 - 0.0076 15.7 0.1 0.3 10.5 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase NACHT PF05729.7 CCD25506.1 - 0.0087 15.7 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.1 CCD25506.1 - 0.009 15.8 0.0 0.026 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCD25506.1 - 0.0096 15.6 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain T2SE PF00437.15 CCD25506.1 - 0.013 14.4 0.2 0.031 13.1 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 CCD25506.1 - 0.017 15.4 0.0 0.052 13.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 CCD25506.1 - 0.019 14.4 0.0 0.049 13.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 CCD25506.1 - 0.027 14.5 0.0 0.078 13.0 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 CCD25506.1 - 0.036 13.2 0.0 0.086 12.0 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.1 CCD25506.1 - 0.04 14.2 0.3 0.04 14.2 0.2 2.8 3 2 0 3 3 2 0 AAA domain MobB PF03205.9 CCD25506.1 - 0.046 13.4 0.1 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Uricase PF01014.13 CCD25506.1 - 0.051 13.6 0.0 7 6.7 0.0 2.5 2 0 0 2 2 2 0 Uricase FANCL_C PF11793.3 CCD25507.1 - 0.00018 21.4 1.3 0.00018 21.4 0.9 1.7 2 0 0 2 2 2 1 FANCL C-terminal domain zf-RING-like PF08746.6 CCD25507.1 - 0.16 11.9 0.3 0.16 11.9 0.2 3.0 3 0 0 3 3 3 0 RING-like domain C1_2 PF03107.11 CCD25507.1 - 0.19 11.8 2.8 6.5 6.9 0.0 2.6 2 0 0 2 2 2 0 C1 domain zf-rbx1 PF12678.2 CCD25507.1 - 0.95 9.6 6.5 7.9 6.6 4.5 2.4 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 CCD25507.1 - 2.8 7.6 10.0 0.44 10.2 0.4 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCD25507.1 - 4.1 7.2 5.9 3.1 7.6 1.0 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Glyco_hydro_31 PF01055.21 CCD25508.1 - 5.9e-133 443.9 0.0 8.1e-133 443.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CCD25508.1 - 1.8e-22 78.9 0.1 7.6e-22 76.9 0.0 2.2 1 0 0 1 1 1 1 Galactose mutarotase-like Claudin_2 PF13903.1 CCD25510.1 - 0.43 10.2 8.2 8.7 5.9 5.4 2.3 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Sugar_tr PF00083.19 CCD25511.1 - 3.2e-161 536.9 35.1 3.6e-161 536.7 24.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD25511.1 - 5e-33 114.2 23.8 5e-33 114.2 16.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCD25512.1 - 2.4e-161 537.3 34.5 2.8e-161 537.1 23.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD25512.1 - 2.1e-33 115.5 22.9 2.1e-33 115.5 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCD25512.1 - 0.00038 18.8 1.7 0.00064 18.0 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) BCNT PF07572.7 CCD25513.1 - 4.9e-27 93.6 0.9 4.9e-27 93.6 0.6 2.7 3 0 0 3 3 3 1 Bucentaur or craniofacial development CDC45 PF02724.9 CCD25513.1 - 0.4 8.6 17.1 0.68 7.8 11.8 1.3 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 CCD25513.1 - 2 7.6 19.2 0.87 8.7 11.7 1.6 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T RRN3 PF05327.6 CCD25513.1 - 3.9 5.4 15.1 6.9 4.6 10.5 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 KH_1 PF00013.24 CCD25514.1 - 2.2e-26 91.2 3.1 2.3e-12 46.3 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCD25514.1 - 3.2e-13 48.9 12.4 3.1e-07 29.8 1.1 3.1 2 0 0 2 2 2 2 KH domain KH_2 PF07650.12 CCD25514.1 - 3.5e-07 29.6 2.6 0.00047 19.6 0.1 2.8 2 1 0 2 2 2 2 KH domain KH_4 PF13083.1 CCD25514.1 - 1.3e-05 24.7 1.7 0.023 14.3 0.0 3.0 2 1 1 3 3 3 2 KH domain KH_5 PF13184.1 CCD25514.1 - 0.033 13.9 0.6 3 7.6 0.0 2.5 2 0 0 2 2 2 0 NusA-like KH domain DUF3277 PF11681.3 CCD25514.1 - 0.14 11.5 0.3 0.3 10.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3277) F-box-like PF12937.2 CCD25515.1 - 0.0012 18.5 0.1 0.0026 17.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCD25515.1 - 0.0021 17.6 0.5 0.0049 16.5 0.3 1.7 1 0 0 1 1 1 1 F-box domain Ku_PK_bind PF08785.6 CCD25515.1 - 0.52 10.2 7.8 1.3 8.9 0.2 3.1 3 1 0 3 3 3 0 Ku C terminal domain like AA_permease PF00324.16 CCD25517.1 - 2.2e-42 145.0 39.2 3.2e-42 144.4 27.1 1.3 1 0 0 1 1 1 1 Amino acid permease Pox_MCEL PF03291.11 CCD25518.1 - 1.4e-97 326.5 0.1 1.4e-97 326.5 0.0 1.4 2 0 0 2 2 2 1 mRNA capping enzyme Methyltransf_12 PF08242.7 CCD25518.1 - 6.2e-09 36.2 0.1 6.4e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCD25518.1 - 3.7e-08 33.2 0.0 7.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCD25518.1 - 1.8e-07 31.5 0.0 5.1e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD25518.1 - 6.2e-07 29.9 0.0 1.2e-06 29.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCD25518.1 - 1.4e-06 27.9 0.0 3.2e-06 26.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD25518.1 - 7.3e-06 26.2 0.0 1.4e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CCD25518.1 - 0.00097 18.2 0.0 0.0032 16.5 0.0 1.9 2 1 0 2 2 2 1 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 CCD25518.1 - 0.0052 15.7 0.0 0.011 14.7 0.0 1.5 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 CCD25518.1 - 0.011 15.7 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.5 CCD25518.1 - 0.084 12.4 1.0 0.56 9.7 0.0 2.1 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase ARD PF03079.9 CCD25518.1 - 0.11 12.4 2.9 0.21 11.5 2.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family DEAD PF00270.24 CCD25519.1 - 8.2e-43 145.8 0.3 1.9e-42 144.6 0.1 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD25519.1 - 1.9e-19 69.2 0.1 4.7e-19 68.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCD25519.1 - 1.5e-05 23.9 0.1 2.6e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Fis1_TPR_N PF14852.1 CCD25519.1 - 0.0041 16.3 0.1 0.0073 15.5 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat Helicase_C_2 PF13307.1 CCD25519.1 - 0.052 13.5 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Helicase C-terminal domain Patatin PF01734.17 CCD25520.1 - 2.5 7.9 6.0 0.21 11.4 0.2 2.1 2 1 0 2 2 2 0 Patatin-like phospholipase PAS PF00989.19 CCD25521.1 - 8.1e-14 51.3 0.4 5.8e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.13 CCD25521.1 - 7.8e-07 28.9 10.8 1.4e-06 28.0 7.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 CCD25521.1 - 0.014 15.7 0.0 0.062 13.6 0.0 2.1 1 0 0 1 1 1 0 PAS domain PAS_8 PF13188.1 CCD25521.1 - 0.14 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 PAS domain tRNA_bind PF01588.15 CCD25522.1 - 7.3e-29 99.4 0.0 1.4e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.1 CCD25522.1 - 0.0018 18.1 0.0 0.0042 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Viral_protease PF08715.5 CCD25522.1 - 0.037 13.0 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 Papain like viral protease DUF4407 PF14362.1 CCD25522.1 - 0.22 10.4 5.1 0.077 11.9 1.6 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Zn_clus PF00172.13 CCD25523.1 - 1.8e-10 40.5 7.2 5.2e-10 39.0 5.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 CCD25524.1 - 2.2e-99 333.0 15.1 2.7e-99 332.7 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD25524.1 - 4.3e-34 117.7 12.8 4.3e-34 117.7 8.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Lig_chan PF00060.21 CCD25524.1 - 0.051 13.3 2.2 0.14 11.8 0.0 2.7 3 0 0 3 3 3 0 Ligand-gated ion channel DUF2207 PF09972.4 CCD25524.1 - 8.4 4.8 20.6 0.041 12.4 6.3 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) HD_3 PF13023.1 CCD25525.1 - 3.2e-41 140.8 0.3 4e-41 140.5 0.2 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 CCD25525.1 - 9.5e-07 28.8 0.2 1.7e-06 28.0 0.1 1.4 1 0 0 1 1 1 1 HD domain HD_2 PF12917.2 CCD25525.1 - 0.0073 16.1 0.4 0.013 15.2 0.3 1.4 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme Glycos_transf_4 PF00953.16 CCD25526.1 - 2.2e-29 102.3 12.4 2.2e-29 102.3 8.6 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 4 SNF2_N PF00176.18 CCD25527.1 - 1.9e-79 266.5 0.6 3.2e-79 265.8 0.4 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CCD25527.1 - 6.7e-31 106.4 2.5 6.7e-31 106.4 1.7 3.2 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 CCD25527.1 - 3.4e-27 95.0 0.4 3.4e-27 95.0 0.2 4.0 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 CCD25527.1 - 1.8e-16 59.7 0.0 1.5e-15 56.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCD25527.1 - 2.2e-12 46.4 0.7 6e-12 44.9 0.5 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 CCD25527.1 - 3.4e-08 33.5 5.2 5.7e-07 29.5 0.0 4.4 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCD25527.1 - 9.5e-05 21.9 0.0 0.00027 20.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase WD40 PF00400.27 CCD25528.1 - 1.1e-09 37.7 3.4 0.31 11.0 0.2 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat MMR_HSR1 PF01926.18 CCD25529.1 - 3.3e-17 62.4 0.4 1e-14 54.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCD25529.1 - 3.3e-08 32.9 0.3 3.5e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 CCD25529.1 - 0.00094 18.4 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CCD25529.1 - 0.0033 16.5 0.0 0.0071 15.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 CCD25529.1 - 0.0041 17.5 0.5 0.12 12.9 0.1 2.5 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 CCD25529.1 - 0.017 14.9 4.4 0.033 13.9 0.1 3.0 3 1 0 3 3 3 0 Dynamin family SRP1_TIP1 PF00660.12 CCD25530.1 - 2e-20 72.5 0.1 2.1e-20 72.5 0.1 1.0 1 0 0 1 1 1 1 Seripauperin and TIP1 family Bystin PF05291.6 CCD25531.1 - 2.8e-123 410.6 0.0 5.4e-123 409.7 0.0 1.4 1 0 0 1 1 1 1 Bystin His_biosynth PF00977.16 CCD25532.1 - 2.7e-44 151.1 0.0 1.3e-43 148.9 0.0 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 CCD25532.1 - 3.5e-28 98.3 0.0 6.2e-28 97.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CCD25532.1 - 2.5e-06 27.1 0.0 4.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 CCD25532.1 - 1.2e-05 24.9 0.0 0.0076 15.8 0.0 2.3 2 0 0 2 2 2 2 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 CCD25532.1 - 0.0092 15.4 0.3 0.1 12.0 0.2 2.1 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 CCD25532.1 - 0.071 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family ThiG PF05690.9 CCD25532.1 - 0.19 10.7 0.0 0.33 9.9 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG DAHP_synth_1 PF00793.15 CCD25533.1 - 9e-103 342.6 0.0 1.1e-102 342.3 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Arrestin_N PF00339.24 CCD25534.1 - 8.5e-05 22.4 2.1 0.00023 21.0 1.5 1.7 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain HTH_30 PF13556.1 CCD25534.1 - 0.04 13.4 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Homeobox_KN PF05920.6 CCD25535.1 - 6.9e-17 60.8 0.5 6.9e-17 60.8 0.4 2.4 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 CCD25535.1 - 5.9e-06 25.8 0.3 2.2e-05 23.9 0.2 2.0 1 0 0 1 1 1 1 Homeobox domain Metallophos PF00149.23 CCD25537.1 - 4.2e-41 140.5 0.1 4.2e-41 140.5 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Sec1 PF00995.18 CCD25540.1 - 3.8e-130 435.2 24.8 4.5e-130 434.9 17.2 1.1 1 0 0 1 1 1 1 Sec1 family TCO89 PF10452.4 CCD25541.1 - 1.9e-89 301.2 82.4 1.9e-89 301.2 57.1 3.1 1 1 1 2 2 2 1 TORC1 subunit TCO89 WD40 PF00400.27 CCD25542.1 - 1.8e-26 90.9 17.1 4.2e-09 35.9 0.3 9.6 10 0 0 10 10 10 6 WD domain, G-beta repeat Ribosomal_L36 PF00444.13 CCD25543.1 - 1.1e-21 76.5 9.3 1.5e-21 76.0 6.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 CCD25543.1 - 0.095 12.0 0.5 0.14 11.4 0.4 1.3 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family RRM_6 PF14259.1 CCD25544.1 - 5e-25 87.2 1.4 3.7e-06 26.8 0.0 5.2 6 0 0 6 6 6 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCD25544.1 - 5.9e-25 86.7 0.9 1.4e-06 27.8 0.0 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD25544.1 - 2e-21 75.5 3.6 1.5e-06 27.9 0.1 5.0 4 1 1 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCD25544.1 - 0.042 13.6 0.2 4.8 7.0 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif MF_alpha_N PF05436.6 CCD25546.1 - 8.5e-23 79.8 0.5 9.8e-23 79.6 0.3 1.1 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus NAD_kinase PF01513.16 CCD25547.1 - 5.2e-54 182.9 0.0 7.1e-54 182.5 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase Glyco_hydro_10 PF00331.15 CCD25547.1 - 0.042 12.8 0.1 0.15 11.0 0.1 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 DAGK_cat PF00781.19 CCD25547.1 - 0.068 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MBOAT PF03062.14 CCD25548.1 - 3.6e-57 193.9 21.8 3.6e-57 193.9 15.1 2.2 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Sad1_UNC PF07738.8 CCD25549.1 - 1.7e-34 118.5 0.1 5e-34 116.9 0.0 1.9 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal FBA_2 PF07735.12 CCD25549.1 - 0.054 13.3 5.8 0.031 14.1 1.0 2.8 2 0 0 2 2 2 0 F-box associated MMS19_C PF12460.3 CCD25554.1 - 1.6e-91 307.1 25.7 1.6e-91 307.1 17.8 4.1 4 0 0 4 4 4 2 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 CCD25554.1 - 1.3e-84 283.5 14.2 4.9e-81 271.8 4.0 4.6 4 1 0 4 4 4 3 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.17 CCD25554.1 - 0.00013 21.7 0.4 0.1 12.7 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat Ipi1_N PF12333.3 CCD25554.1 - 0.00072 19.4 7.4 7.5 6.5 0.0 5.7 5 1 0 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation YobH PF13996.1 CCD25554.1 - 0.018 14.9 0.1 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 YobH-like protein HEAT_2 PF13646.1 CCD25554.1 - 0.037 14.3 0.1 9.6 6.5 0.0 4.3 3 2 2 5 5 5 0 HEAT repeats HEAT_EZ PF13513.1 CCD25554.1 - 0.056 13.9 4.4 0.17 12.4 0.0 3.7 5 0 0 5 5 5 0 HEAT-like repeat Fork_head PF00250.13 CCD25555.1 - 1e-35 121.6 0.6 3.3e-35 119.9 0.4 1.9 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CCD25555.1 - 5.4e-09 36.0 0.2 3.2e-08 33.5 0.0 2.6 2 0 0 2 2 2 1 FHA domain Rifin_STEVOR PF02009.11 CCD25555.1 - 0.017 14.8 19.8 0.011 15.3 11.3 2.5 1 1 1 2 2 2 0 Rifin/stevor family Ribosomal_L13 PF00572.13 CCD25556.1 - 3.2e-26 91.8 0.0 5.9e-26 91.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 Tom7 PF08038.7 CCD25557.1 - 4.3e-19 67.6 0.1 5.5e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 TOM7 family 2-oxoacid_dh PF00198.18 CCD25558.1 - 1.5e-75 253.4 0.5 2.1e-75 252.9 0.3 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCD25558.1 - 3.1e-16 58.7 0.1 7e-16 57.6 0.1 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 CCD25558.1 - 3.2e-14 52.2 0.2 7.8e-14 51.0 0.0 1.8 2 0 0 2 2 2 1 e3 binding domain DUF2481 PF10654.4 CCD25558.1 - 0.09 12.4 0.2 2 8.0 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2481) RNase_HII PF01351.13 CCD25559.1 - 1.2e-63 214.3 0.0 1.5e-63 214.0 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Brix PF04427.13 CCD25561.1 - 1.7e-45 155.0 0.2 2.3e-45 154.6 0.1 1.2 1 0 0 1 1 1 1 Brix domain Bromodomain PF00439.20 CCD25561.1 - 0.097 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain DUF1752 PF08550.5 CCD25562.1 - 1.2e-11 43.9 0.1 3.2e-11 42.6 0.0 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DnaJ PF00226.26 CCD25563.1 - 2.8e-21 75.0 3.6 5.6e-21 74.0 2.5 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCD25563.1 - 8.7e-14 51.1 1.9 4.9e-12 45.5 0.0 2.9 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCD25563.1 - 1.8e-09 37.5 17.2 5.3e-09 36.0 11.9 1.9 1 0 0 1 1 1 1 DnaJ central domain DUF3899 PF13038.1 CCD25564.1 - 0.38 10.9 2.7 1.3 9.2 1.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) EOS1 PF12326.3 CCD25566.1 - 1.5e-52 177.1 2.6 4.9e-52 175.5 0.1 2.3 2 1 0 2 2 2 1 N-glycosylation protein Ribosomal_S13 PF00416.17 CCD25567.1 - 8e-22 77.7 0.1 8.9e-22 77.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CCD25567.1 - 0.0067 15.0 0.0 0.0067 15.0 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) H2TH PF06831.9 CCD25567.1 - 0.034 13.8 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain IMS_HHH PF11798.3 CCD25567.1 - 0.04 13.9 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 IMS family HHH motif IL5 PF02025.10 CCD25567.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Interleukin 5 DNA_mis_repair PF01119.14 CCD25569.1 - 1.1e-23 83.0 2.3 1.1e-23 82.9 0.2 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 CCD25569.1 - 1.4e-22 79.8 0.0 3.2e-22 78.7 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 CCD25569.1 - 3.5e-11 42.8 0.1 3.5e-11 42.8 0.1 2.9 4 0 0 4 4 4 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCD25569.1 - 1.9e-10 40.4 0.0 6.3e-10 38.7 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mito_carr PF00153.22 CCD25570.1 - 6.5e-61 202.0 4.2 4.2e-21 74.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CCD25570.1 - 4.3e-14 52.4 7.3 4e-11 42.8 0.9 3.1 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 CCD25570.1 - 2.2e-09 35.9 4.8 0.013 14.7 0.1 4.7 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 CCD25570.1 - 2.2e-08 33.3 3.4 0.089 12.7 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CCD25570.1 - 9.4e-08 31.5 2.1 4.1e-06 26.3 0.2 2.7 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.1 CCD25570.1 - 0.0033 16.6 4.2 0.24 10.8 0.2 3.1 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 CCD25570.1 - 0.0071 16.3 3.8 0.018 15.0 0.3 2.3 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Snapin_Pallidin PF14712.1 CCD25571.1 - 0.001 19.3 5.4 0.0013 19.0 3.8 1.1 1 0 0 1 1 1 1 Snapin/Pallidin YscO PF07321.7 CCD25571.1 - 0.0031 17.3 1.5 0.0045 16.8 1.1 1.3 1 0 0 1 1 1 1 Type III secretion protein YscO Sbi-IV PF11621.3 CCD25571.1 - 0.073 13.2 0.7 0.1 12.7 0.5 1.3 1 0 0 1 1 1 0 C3 binding domain 4 of IgG-bind protein SBI DUF972 PF06156.8 CCD25571.1 - 0.1 12.9 2.7 1.4 9.3 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Nup54 PF13874.1 CCD25571.1 - 0.11 12.0 1.9 0.18 11.5 0.9 1.6 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Uds1 PF15456.1 CCD25571.1 - 0.45 10.5 4.8 2.1 8.3 3.3 1.9 1 1 0 1 1 1 0 Up-regulated During Septation TPR_MLP1_2 PF07926.7 CCD25571.1 - 0.47 10.2 5.6 1.1 9.0 3.9 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Myc-LZ PF02344.10 CCD25571.1 - 0.5 10.0 10.9 0.18 11.4 1.4 3.0 3 0 0 3 3 3 0 Myc leucine zipper domain DUF2205 PF10224.4 CCD25571.1 - 0.5 9.9 6.4 1.1 8.8 1.6 2.2 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) C2 PF00168.25 CCD25572.1 - 8e-39 131.3 2.4 3.1e-19 68.6 0.1 4.6 4 0 0 4 4 4 4 C2 domain DUF2404 PF10296.4 CCD25572.1 - 0.01 15.9 0.3 0.46 10.6 0.0 3.4 2 1 1 3 3 3 0 Putative integral membrane protein conserved region (DUF2404) DUF3810 PF12725.2 CCD25572.1 - 0.083 11.7 1.0 0.63 8.8 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) DNA_topoisoIV PF00521.15 CCD25573.1 - 1.1e-123 413.3 0.9 1.9e-123 412.5 0.0 1.9 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CCD25573.1 - 4.5e-33 113.9 5.4 9.8e-33 112.7 3.7 1.6 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CCD25573.1 - 4.7e-13 48.9 0.0 1.7e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CCD25573.1 - 1.2e-09 37.9 0.0 2.7e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ras PF00071.17 CCD25574.1 - 7.7e-50 168.4 0.0 8.8e-50 168.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD25574.1 - 9.4e-15 55.1 0.0 1.2e-14 54.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCD25574.1 - 2.1e-08 33.5 0.0 3e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 CCD25574.1 - 0.031 13.7 0.0 5.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 CCD25574.1 - 0.13 11.4 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NST1 PF13945.1 CCD25575.1 - 9.9e-14 51.8 0.3 9.9e-14 51.8 0.2 10.7 7 4 6 13 13 13 1 Salt tolerance down-regulator CD20 PF04103.10 CCD25575.1 - 0.19 11.6 3.3 0.83 9.5 0.0 3.8 2 0 0 2 2 2 0 CD20-like family zf-CCCH PF00642.19 CCD25576.1 - 0.00033 20.2 0.2 0.00033 20.2 0.1 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ADSL_C PF10397.4 CCD25576.1 - 0.62 10.1 3.4 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 Adenylosuccinate lyase C-terminus DUF2183 PF09949.4 CCD25577.1 - 3e-32 110.5 0.0 1.2e-31 108.5 0.0 2.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Mem_trans PF03547.13 CCD25578.1 - 2.2e-83 279.7 0.1 8.6e-83 277.7 0.0 1.8 1 1 0 1 1 1 1 Membrane transport protein Ribosomal_S7e PF01251.13 CCD25579.1 - 1.2e-23 83.5 0.1 1.3e-23 83.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF4265 PF14085.1 CCD25579.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4265) ING PF12998.2 CCD25580.1 - 1.4e-21 76.6 0.4 1.4e-21 76.6 0.3 2.1 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CCD25580.1 - 3.8e-09 36.0 7.6 6.6e-09 35.3 5.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CCD25580.1 - 0.0062 16.6 0.8 0.019 15.1 0.5 1.9 1 0 0 1 1 1 1 PHD-like zinc-binding domain PHD_2 PF13831.1 CCD25580.1 - 0.0087 15.3 1.6 0.019 14.2 1.1 1.6 1 0 0 1 1 1 1 PHD-finger DNA_pol_viral_N PF00242.12 CCD25580.1 - 0.085 11.8 10.8 0.13 11.2 7.5 1.3 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain zf-RING-like PF08746.6 CCD25580.1 - 1.2 9.1 3.9 2.4 8.2 2.7 1.5 1 0 0 1 1 1 0 RING-like domain DUF572 PF04502.8 CCD25580.1 - 9.5 5.3 21.8 13 4.8 15.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DAD PF02109.11 CCD25581.1 - 1.3e-40 137.9 3.5 1.5e-40 137.7 2.4 1.2 1 0 0 1 1 1 1 DAD family DUF2207 PF09972.4 CCD25581.1 - 0.14 10.7 0.6 0.15 10.5 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TrbL PF04610.9 CCD25581.1 - 0.78 9.3 6.2 0.77 9.4 3.2 1.8 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein Y_phosphatase2 PF03162.8 CCD25582.1 - 2.1e-57 193.0 0.0 3.1e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCD25582.1 - 1e-05 25.8 0.0 5.5e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CCD25582.1 - 0.045 13.3 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain DUF4611 PF15387.1 CCD25582.1 - 1.1 9.4 4.6 2.7 8.2 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) ApoO PF09769.4 CCD25583.1 - 4.4e-06 26.5 0.1 0.029 14.0 0.0 3.0 2 1 1 3 3 3 2 Apolipoprotein O Aa_trans PF01490.13 CCD25584.1 - 2.8e-90 302.7 30.6 3.4e-90 302.4 21.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein YuzL PF14115.1 CCD25584.1 - 0.11 12.7 0.6 0.29 11.4 0.4 1.7 1 0 0 1 1 1 0 YuzL-like protein DNA_pol_B PF00136.16 CCD25585.1 - 1e-117 393.8 6.1 1.7e-117 393.1 4.2 1.4 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 CCD25585.1 - 1.4e-67 226.7 1.3 2.5e-67 225.8 0.9 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 CCD25585.1 - 2.3e-45 154.9 0.0 4.2e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C2H2_6 PF13912.1 CCD25585.1 - 0.85 9.6 2.9 5.9 6.9 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Syja_N PF02383.13 CCD25588.1 - 1.2e-89 300.2 7.7 2.7e-89 299.1 5.4 1.6 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CCD25588.1 - 8.7e-25 88.0 0.0 1.5e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Remorin_N PF03766.8 CCD25588.1 - 3.3 7.5 8.6 0.19 11.4 1.8 2.1 2 0 0 2 2 2 0 Remorin, N-terminal region His_Phos_1 PF00300.17 CCD25589.1 - 5e-20 72.1 0.0 6.7e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 CCD25589.1 - 0.0023 17.3 0.0 0.0081 15.5 0.0 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RRM_1 PF00076.17 CCD25590.1 - 2.6e-19 68.6 0.2 1.1e-18 66.6 0.0 2.1 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD25590.1 - 6.5e-13 48.4 0.0 1.5e-12 47.2 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD25590.1 - 9.7e-10 38.1 0.0 2.1e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2129 PF09902.4 CCD25590.1 - 0.041 13.6 1.7 6.1 6.7 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2129) Limkain-b1 PF11608.3 CCD25590.1 - 0.15 11.7 0.0 0.15 11.7 0.0 2.9 3 2 1 4 4 4 0 Limkain b1 VitD-bind_III PF09164.5 CCD25590.1 - 0.18 11.4 1.3 0.56 9.8 0.9 1.8 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DUF445 PF04286.7 CCD25590.1 - 0.64 9.4 7.3 0.87 9.0 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Cyt-b5 PF00173.23 CCD25591.1 - 9.5e-28 95.8 0.1 1.2e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DEAD PF00270.24 CCD25592.1 - 2e-44 151.0 0.0 4.9e-43 146.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD25592.1 - 5.1e-28 96.7 0.0 1.2e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCD25592.1 - 0.00067 19.5 0.0 0.0019 18.0 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CCD25592.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain DUF1253 PF06862.7 CCD25592.1 - 0.12 10.7 0.0 0.89 7.8 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1253) RNA_pol_L_2 PF13656.1 CCD25593.1 - 4.3e-30 102.9 0.0 6.3e-30 102.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CCD25593.1 - 4e-14 51.4 0.0 6.3e-14 50.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Myc_N PF01056.13 CCD25593.1 - 1.1 8.3 5.6 1.3 8.0 3.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF2417 PF10329.4 CCD25594.1 - 1.1e-45 155.9 8.7 1.7e-45 155.2 6.0 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 CCD25594.1 - 1.7e-07 31.3 0.0 2.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD25594.1 - 0.00029 20.4 0.0 0.00053 19.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold FHA PF00498.21 CCD25595.1 - 4.7e-15 55.4 0.1 4.7e-15 55.4 0.0 2.7 3 0 0 3 3 2 1 FHA domain zf-RING_2 PF13639.1 CCD25595.1 - 4.8e-06 26.2 10.0 8.4e-06 25.5 7.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCD25595.1 - 4.3e-05 23.5 6.7 9.3e-05 22.4 4.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CCD25595.1 - 0.0023 17.5 10.5 0.0045 16.6 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCD25595.1 - 0.0026 17.5 5.9 0.0061 16.3 4.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 CCD25595.1 - 0.014 15.1 8.4 0.025 14.3 5.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain Vps39_2 PF10367.4 CCD25595.1 - 0.019 15.1 3.1 0.072 13.2 2.2 2.0 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_2 PF13923.1 CCD25595.1 - 0.048 13.7 11.8 0.092 12.7 8.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sec_GG PF07549.9 CCD25595.1 - 0.063 12.5 0.4 0.15 11.3 0.3 1.6 1 0 0 1 1 1 0 SecD/SecF GG Motif zf-HC5HC2H PF13771.1 CCD25595.1 - 0.16 12.1 6.0 0.37 10.9 4.2 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 CCD25595.1 - 1.8 8.5 7.1 3.9 7.5 4.9 1.6 1 0 0 1 1 1 0 RING-like domain Malate_synthase PF01274.17 CCD25596.1 - 4.8e-217 721.1 0.0 5.7e-217 720.8 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DCP2 PF05026.8 CCD25597.1 - 6.3e-31 106.1 0.4 2e-30 104.4 0.3 2.0 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 CCD25597.1 - 1.2e-13 50.8 0.0 3e-13 49.5 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Consortin_C PF15281.1 CCD25597.1 - 0.14 11.6 8.0 2.3 7.7 1.5 3.5 3 0 0 3 3 3 0 Consortin C-terminus DUF2392 PF10288.4 CCD25598.1 - 1.4e-31 108.9 0.1 3.2e-31 107.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) DZR PF12773.2 CCD25598.1 - 0.92 9.3 3.5 0.63 9.8 0.5 2.1 2 0 0 2 2 2 0 Double zinc ribbon TPR_11 PF13414.1 CCD25599.1 - 9.1e-37 124.5 24.9 1.1e-14 53.8 1.6 6.5 5 1 1 6 6 6 5 TPR repeat TPR_1 PF00515.23 CCD25599.1 - 1.6e-28 97.1 34.1 9.6e-06 24.9 0.3 9.8 9 1 1 10 10 9 7 Tetratricopeptide repeat TPR_2 PF07719.12 CCD25599.1 - 1.1e-27 93.6 35.8 6.5e-05 22.5 0.1 10.9 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 CCD25599.1 - 4.8e-19 68.4 15.1 4e-05 24.1 0.4 6.4 6 1 1 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 CCD25599.1 - 1.7e-16 60.3 18.0 3.4e-05 24.0 2.3 6.6 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 CCD25599.1 - 8.7e-16 57.6 20.7 0.00099 19.0 0.4 7.1 5 3 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 CCD25599.1 - 8.7e-14 50.5 14.6 0.00019 21.3 0.1 8.0 9 0 0 9 9 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCD25599.1 - 1.6e-13 49.9 13.9 0.021 15.4 0.1 9.3 5 3 5 10 10 10 3 Tetratricopeptide repeat Apc3 PF12895.2 CCD25599.1 - 1.1e-08 35.1 17.1 0.00099 19.1 1.0 5.0 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCD25599.1 - 6.1e-08 31.8 34.0 0.072 12.8 0.4 8.4 8 2 2 10 10 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 CCD25599.1 - 4.9e-05 22.8 16.3 0.064 13.0 0.9 6.5 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCD25599.1 - 0.00012 21.8 2.8 0.43 10.4 0.0 4.9 5 1 1 6 6 6 1 Tetratricopeptide repeat Peptidase_S49_N PF08496.5 CCD25599.1 - 0.0051 16.6 2.4 0.0051 16.6 1.6 2.7 3 0 0 3 3 3 1 Peptidase family S49 N-terminal TPR_20 PF14561.1 CCD25599.1 - 0.013 15.6 13.1 0.21 11.7 2.7 4.2 5 1 0 5 5 3 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.11 CCD25599.1 - 0.017 14.9 1.9 0.017 14.9 1.3 3.7 4 0 0 4 4 3 0 Exonuclease VII small subunit TPR_6 PF13174.1 CCD25599.1 - 0.1 13.1 27.6 1 9.9 0.4 8.8 12 2 1 13 13 7 0 Tetratricopeptide repeat NARP1 PF12569.3 CCD25599.1 - 0.29 9.8 0.0 0.29 9.8 0.0 5.2 3 2 2 5 5 5 0 NMDA receptor-regulated protein 1 TPR_4 PF07721.9 CCD25599.1 - 0.68 10.5 3.1 17 6.1 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L35p PF01632.14 CCD25600.1 - 1.3e-06 28.2 3.6 2e-06 27.6 2.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L35 PDZ_1 PF12812.2 CCD25601.1 - 2.1e-53 178.1 0.0 4.9e-34 116.0 0.0 3.7 3 0 0 3 3 3 2 PDZ-like domain PDZ_2 PF13180.1 CCD25601.1 - 2.8e-12 46.3 2.3 0.0003 20.6 0.2 4.4 4 0 0 4 4 4 2 PDZ domain Trypsin_2 PF13365.1 CCD25601.1 - 2.8e-12 46.6 0.1 2.5e-11 43.5 0.0 2.3 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 CCD25601.1 - 2.4e-09 37.2 0.0 2.7e-05 24.2 0.0 2.8 2 0 0 2 2 2 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 CCD25601.1 - 5.2e-06 26.1 0.2 0.0035 17.1 0.0 3.3 3 0 0 3 3 3 1 Tricorn protease PDZ domain Trypsin PF00089.21 CCD25601.1 - 6.7e-05 22.5 0.0 0.00062 19.4 0.0 2.2 2 0 0 2 2 2 1 Trypsin DUF31 PF01732.11 CCD25601.1 - 0.011 15.1 0.2 0.026 13.8 0.1 1.7 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.16 CCD25601.1 - 0.041 13.2 0.1 0.097 12.0 0.1 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Peptidase_S46 PF10459.4 CCD25601.1 - 0.25 9.7 0.1 1.6 7.0 0.0 2.1 3 0 0 3 3 3 0 Peptidase S46 Gar1 PF04410.9 CCD25602.1 - 5.3e-46 155.8 0.3 5.3e-46 155.8 0.2 3.1 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region PAT1 PF09770.4 CCD25602.1 - 4 5.5 67.0 0.034 12.4 39.9 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Spc97_Spc98 PF04130.8 CCD25603.1 - 6.1e-65 219.5 29.2 1.5e-64 218.2 20.2 1.6 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3402 PF11882.3 CCD25604.1 - 1.8e-98 330.3 6.6 3e-98 329.5 4.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 CCD25604.1 - 8.7e-65 218.4 3.1 1.4e-64 217.7 2.1 1.3 1 0 0 1 1 1 1 N1221-like protein AD PF09793.4 CCD25605.1 - 4.1e-21 74.6 0.1 4.1e-21 74.6 0.1 1.6 2 0 0 2 2 2 1 Anticodon-binding domain LSM14 PF12701.2 CCD25605.1 - 0.0031 17.2 0.3 0.0055 16.4 0.2 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain Sec3-PIP2_bind PF15277.1 CCD25605.1 - 0.023 14.5 1.1 0.074 12.9 0.3 1.9 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH DSPc PF00782.15 CCD25606.1 - 1.6e-08 34.2 0.0 4.3e-08 32.7 0.0 1.9 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCD25606.1 - 8.7e-06 25.2 0.1 4.1e-05 23.0 0.0 2.0 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCD25606.1 - 0.059 13.4 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CCD25606.1 - 0.071 13.3 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family AAA_18 PF13238.1 CCD25607.1 - 7.3e-09 36.0 1.3 1.6e-07 31.6 0.4 2.6 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 CCD25607.1 - 3.9e-06 27.6 1.0 7e-05 23.6 0.7 2.7 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 CCD25607.1 - 0.0011 18.5 0.1 0.0024 17.4 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family tRNA_lig_kinase PF08303.6 CCD25607.1 - 0.0062 16.4 0.5 0.044 13.6 0.0 2.2 2 0 0 2 2 2 1 tRNA ligase kinase domain AAA_22 PF13401.1 CCD25607.1 - 0.03 14.4 0.8 0.14 12.2 0.6 2.0 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 CCD25607.1 - 0.055 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_28 PF13521.1 CCD25607.1 - 0.099 12.6 0.3 0.19 11.6 0.2 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CCD25607.1 - 0.1 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 CCD25607.1 - 0.13 11.1 0.1 0.23 10.3 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SecE PF00584.15 CCD25608.1 - 1.4e-10 40.5 0.1 1.5e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex ASFV_p27 PF06556.6 CCD25608.1 - 0.09 12.6 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 IAP-like protein p27 C-terminus MFS_1 PF07690.11 CCD25609.1 - 8.6e-29 100.3 53.5 2.1e-23 82.6 27.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily FAM176 PF14851.1 CCD25609.1 - 0.32 10.6 0.1 0.32 10.6 0.0 3.5 4 0 0 4 4 4 0 FAM176 family CDP-OH_P_transf PF01066.16 CCD25610.1 - 1.2e-14 54.4 9.4 1.2e-14 54.4 6.5 2.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Tom22 PF04281.8 CCD25611.1 - 1.9e-49 166.7 1.7 2.2e-49 166.4 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF4407 PF14362.1 CCD25611.1 - 0.012 14.5 0.2 0.016 14.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GNAT_acetyltr_2 PF13718.1 CCD25612.1 - 9.8e-82 273.0 0.0 2.2e-81 271.8 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CCD25612.1 - 1.1e-66 223.8 0.0 6.6e-66 221.3 0.0 2.4 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 CCD25612.1 - 8e-39 131.2 0.1 3e-38 129.3 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CCD25612.1 - 1.3e-37 127.9 1.8 3.8e-37 126.4 1.2 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Sigma70_r4_2 PF08281.7 CCD25612.1 - 0.022 14.2 0.2 1.2 8.6 0.0 2.8 2 0 0 2 2 2 0 Sigma-70, region 4 DEAD PF00270.24 CCD25612.1 - 0.024 14.1 0.0 0.09 12.2 0.0 1.9 2 0 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.1 CCD25612.1 - 0.041 13.6 0.0 1.3 8.8 0.0 2.7 2 0 0 2 2 2 0 Part of AAA domain Acetyltransf_7 PF13508.1 CCD25612.1 - 0.057 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2120 PF09893.4 CCD25612.1 - 0.062 13.2 4.4 0.077 12.9 2.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) Nefa_Nip30_N PF10187.4 CCD25613.1 - 5.4e-06 26.5 15.6 5.4e-06 26.5 10.8 2.0 1 1 1 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 ADH_zinc_N PF00107.21 CCD25614.1 - 4.1e-16 58.6 0.0 7.3e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCD25614.1 - 4.2e-05 23.2 0.2 0.00048 19.8 0.1 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain FKBP_C PF00254.23 CCD25615.1 - 6.2e-32 109.4 0.0 7.3e-32 109.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Eaf7 PF07904.8 CCD25616.1 - 3.5e-26 90.9 5.4 3.5e-26 90.9 3.7 3.6 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 S4 PF01479.20 CCD25617.1 - 3.3e-16 58.4 0.0 8.1e-16 57.1 0.0 1.7 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 CCD25617.1 - 0.0071 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain LysM PF01476.15 CCD25617.1 - 0.0071 16.2 0.1 0.22 11.4 0.1 2.9 2 1 0 2 2 2 1 LysM domain 7TMR-HDED PF07697.6 CCD25617.1 - 2.7 7.6 13.0 0.72 9.5 6.5 1.9 2 1 0 2 2 2 0 7TM-HD extracellular CAP_N PF01213.14 CCD25618.1 - 8.2e-100 334.1 6.5 1.1e-99 333.6 4.5 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CCD25618.1 - 2.2e-60 202.6 2.0 3.7e-60 201.8 1.4 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal gpUL132 PF11359.3 CCD25619.1 - 0.06 12.6 3.2 0.088 12.1 2.2 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 S-antigen PF05756.6 CCD25619.1 - 0.13 12.2 0.2 0.13 12.2 0.2 2.2 2 1 0 2 2 2 0 S-antigen protein DUF4611 PF15387.1 CCD25619.1 - 0.38 10.9 5.0 12 6.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) SF3b10 PF07189.6 CCD25620.1 - 3.3e-26 90.8 0.3 4e-26 90.6 0.2 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Rab5-bind PF09311.6 CCD25620.1 - 0.03 14.2 1.5 0.035 14.0 1.0 1.2 1 0 0 1 1 1 0 Rabaptin-like protein Prefoldin_3 PF13758.1 CCD25620.1 - 0.13 12.0 0.9 0.17 11.6 0.6 1.3 1 1 0 1 1 1 0 Prefoldin subunit Tho2 PF11262.3 CCD25621.1 - 1.6e-49 168.6 10.4 1.6e-49 168.6 7.2 3.6 3 1 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 CCD25621.1 - 7.4e-25 86.5 0.3 2.2e-24 85.0 0.2 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit C2 PF00168.25 CCD25622.1 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.6 1 0 0 1 1 1 1 C2 domain DDA1 PF10172.4 CCD25622.1 - 0.0074 16.0 0.0 0.029 14.2 0.0 2.0 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase RNA_pol_3_Rpc31 PF11705.3 CCD25623.1 - 2.5e-66 223.9 18.5 3.9e-66 223.3 12.8 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Tom37_C PF11801.3 CCD25623.1 - 0.054 13.3 0.1 0.054 13.3 0.1 2.0 2 0 0 2 2 2 0 Tom37 C-terminal domain PcfJ PF14284.1 CCD25623.1 - 0.066 12.7 0.3 0.066 12.7 0.2 1.8 2 0 0 2 2 2 0 PcfJ-like protein PGA2 PF07543.7 CCD25624.1 - 2.1e-16 60.0 10.9 2.3e-09 37.1 0.4 2.0 1 1 1 2 2 2 2 Protein trafficking PGA2 GBP_C PF02841.9 CCD25624.1 - 0.03 13.5 3.2 0.036 13.2 2.2 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain AA_kinase PF00696.23 CCD25624.1 - 0.089 12.3 0.0 0.093 12.2 0.0 1.2 1 0 0 1 1 1 0 Amino acid kinase family DUF1378 PF07125.6 CCD25624.1 - 0.35 10.8 1.4 3.7 7.5 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1378) Rotamase_2 PF13145.1 CCD25624.1 - 0.53 10.9 4.3 0.99 10.0 2.9 1.7 1 1 0 1 1 1 0 PPIC-type PPIASE domain UPRTase PF14681.1 CCD25625.1 - 7.2e-77 257.2 0.0 9.1e-77 256.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CCD25625.1 - 0.004 16.8 0.0 0.0062 16.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 CCD25625.1 - 0.067 12.9 0.2 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) DUF2009 PF09418.5 CCD25626.1 - 5.1e-224 744.1 4.8 6.3e-224 743.9 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 CCD25626.1 - 2.3e-07 30.5 4.6 4.8e-07 29.5 3.2 1.5 1 0 0 1 1 1 1 B-box zinc finger IBR PF01485.16 CCD25626.1 - 0.034 14.0 4.1 0.079 12.8 2.8 1.5 1 0 0 1 1 1 0 IBR domain EI24 PF07264.6 CCD25627.1 - 0.052 12.9 0.2 0.065 12.6 0.1 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Pga1 PF10333.4 CCD25630.1 - 1.3e-32 112.9 3.7 4.3e-32 111.1 2.6 1.7 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator INSIG PF07281.7 CCD25631.1 - 6.1e-09 35.4 2.7 1.2e-08 34.5 1.3 1.8 1 1 1 2 2 2 1 Insulin-induced protein (INSIG) zf-AN1 PF01428.11 CCD25632.1 - 2.1e-10 40.3 12.7 2.1e-10 40.3 8.8 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger Pkinase PF00069.20 CCD25633.1 - 1.1e-35 123.0 1.0 3.7e-35 121.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25633.1 - 2.9e-14 52.7 0.6 6.4e-14 51.6 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Prefoldin_2 PF01920.15 CCD25634.1 - 6.4e-23 80.5 13.5 7.6e-23 80.3 9.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit SMK-1 PF04802.10 CCD25634.1 - 0.00081 18.9 3.2 0.00095 18.7 2.2 1.1 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Nop16 PF09420.5 CCD25634.1 - 0.026 14.6 1.0 0.035 14.1 0.7 1.2 1 0 0 1 1 1 0 Ribosome biogenesis protein Nop16 DivIC PF04977.10 CCD25634.1 - 5.2 6.6 12.5 1.8 8.1 0.5 2.4 1 1 2 3 3 3 0 Septum formation initiator Seryl_tRNA_N PF02403.17 CCD25634.1 - 7 6.7 12.5 3.1 7.8 2.0 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain A_deaminase PF00962.17 CCD25635.1 - 2.5e-91 306.0 0.0 2.8e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF3889 PF13028.1 CCD25635.1 - 0.1 12.2 1.1 0.76 9.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3889) Ammonium_transp PF00909.16 CCD25636.1 - 2.3e-126 421.4 27.0 2.6e-126 421.2 18.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3185 PF11381.3 CCD25636.1 - 0.061 13.0 11.3 1.3 8.7 0.2 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3185) Asparaginase PF00710.15 CCD25637.1 - 2.5e-18 66.0 5.0 8.9e-18 64.1 3.5 1.9 1 1 0 1 1 1 1 Asparaginase Pkinase PF00069.20 CCD25638.1 - 1.4e-57 194.8 5.9 1.5e-39 135.7 0.1 2.8 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25638.1 - 3e-24 85.4 9.2 3.2e-20 72.3 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_C PF00433.19 CCD25638.1 - 0.0021 18.5 0.1 0.012 16.1 0.1 2.4 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 CCD25638.1 - 0.0027 16.8 0.3 0.018 14.1 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD25638.1 - 0.019 14.6 0.1 0.83 9.3 0.1 2.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCD25638.1 - 0.027 13.3 0.1 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 CCD25638.1 - 0.12 11.0 0.1 0.12 11.0 0.1 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Ribosomal_L44 PF00935.14 CCD25639.1 - 2.6e-34 117.0 11.0 3.9e-34 116.4 7.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 zf-tcix PF14952.1 CCD25640.1 - 0.0068 15.7 6.1 0.15 11.4 0.9 2.2 2 0 0 2 2 2 2 Putative treble-clef, zinc-finger, Zn-binding DZR PF12773.2 CCD25640.1 - 0.028 14.2 2.5 0.041 13.7 1.7 1.3 1 0 0 1 1 1 0 Double zinc ribbon UPF0547 PF10571.4 CCD25640.1 - 0.042 13.5 1.1 0.081 12.6 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 DNA_ligase_ZBD PF03119.11 CCD25640.1 - 0.061 13.0 3.3 0.63 9.7 2.3 2.3 1 1 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-C4_Topoisom PF01396.14 CCD25640.1 - 0.07 12.6 3.0 0.11 11.9 2.1 1.4 1 0 0 1 1 1 0 Topoisomerase DNA binding C4 zinc finger ADK_lid PF05191.9 CCD25640.1 - 0.15 11.7 2.5 0.91 9.2 0.7 2.2 2 0 0 2 2 2 0 Adenylate kinase, active site lid Zn-ribbon_8 PF09723.5 CCD25640.1 - 0.38 10.7 3.6 1.3 8.9 1.1 2.2 2 0 0 2 2 2 0 Zinc ribbon domain IBR PF01485.16 CCD25640.1 - 0.99 9.3 4.8 0.94 9.3 0.4 2.0 1 1 1 2 2 2 0 IBR domain GTP_EFTU PF00009.22 CCD25641.1 - 1.1e-53 181.4 0.0 1.9e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CCD25641.1 - 6.5e-14 51.5 0.0 2.1e-13 49.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCD25641.1 - 6.3e-10 39.0 0.1 2.1e-09 37.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CCD25641.1 - 2.1e-09 37.1 0.0 6.2e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 CCD25641.1 - 1.1e-06 28.1 0.0 9.4e-06 25.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 CCD25641.1 - 0.0023 17.9 0.0 0.0067 16.3 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Aft1_OSA PF11785.3 CCD25645.1 - 2.2e-07 31.3 1.7 2.2e-07 31.3 1.2 5.0 4 2 0 4 4 4 1 Aft1 osmotic stress response (OSM) domain bZIP_1 PF00170.16 CCD25645.1 - 4e-07 29.8 2.3 4e-07 29.8 1.6 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CCD25645.1 - 0.0044 16.8 5.0 0.0044 16.8 3.5 2.5 2 0 0 2 2 2 1 Basic region leucine zipper FAA_hydrolase PF01557.13 CCD25646.1 - 7e-45 153.1 0.0 1e-44 152.6 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family PS_Dcarbxylase PF02666.10 CCD25647.1 - 1.2e-75 253.2 0.0 2e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Rota_NS26 PF01525.11 CCD25647.1 - 0.23 11.2 3.1 0.59 9.8 2.1 1.8 1 1 0 1 1 1 0 Rotavirus NS26 Apc1 PF12859.2 CCD25648.1 - 2.2e-12 47.1 0.1 2.2e-12 47.1 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 CCD25648.1 - 0.00024 21.1 7.1 0.33 11.2 0.6 5.0 4 0 0 4 4 4 2 Proteasome/cyclosome repeat RRM_1 PF00076.17 CCD25650.1 - 4e-29 100.0 1.5 7.3e-19 67.1 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD25650.1 - 6.2e-23 80.5 0.4 3.7e-14 52.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD25650.1 - 3.8e-13 49.0 1.1 5.4e-08 32.5 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCD25650.1 - 0.0018 18.0 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif C-term_anchor PF13461.1 CCD25650.1 - 0.099 13.1 1.6 6 7.4 0.1 2.8 2 0 0 2 2 2 0 Cell-wall surface anchor repeat DUF912 PF06024.7 CCD25651.1 - 0.0043 17.0 0.0 0.04 13.9 0.0 2.5 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribosomal_L22 PF00237.14 CCD25652.1 - 2.4e-19 69.2 0.0 4.4e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribosomal_S3_C PF00189.15 CCD25653.1 - 1.7e-15 56.9 0.1 3.1e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CCD25653.1 - 7.2e-12 44.6 0.1 2.5e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 KH domain Ras PF00071.17 CCD25654.1 - 7.8e-44 148.9 0.0 2.8e-43 147.1 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CCD25654.1 - 4.2e-14 53.0 0.2 2.7e-13 50.4 0.0 2.3 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCD25654.1 - 1.2e-05 24.6 0.6 0.00019 20.7 0.0 2.6 2 1 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCD25654.1 - 0.0008 18.8 0.4 0.0018 17.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCD25654.1 - 0.048 12.7 2.6 0.15 11.1 0.0 2.7 3 1 0 3 3 3 0 Gtr1/RagA G protein conserved region PmbA_TldD PF01523.11 CCD25654.1 - 0.058 12.6 2.6 0.089 12.0 1.8 1.3 1 0 0 1 1 1 0 Putative modulator of DNA gyrase adh_short PF00106.20 CCD25655.1 - 8.7e-08 32.2 0.0 1.5e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCD25655.1 - 2.6e-05 23.9 0.0 4.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCD25655.1 - 0.004 16.9 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase SR-25 PF10500.4 CCD25655.1 - 0.27 10.6 19.1 0.41 10.0 13.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 CCD25656.1 - 7.1e-08 32.0 1.4 0.012 15.4 0.1 4.3 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase PF00069.20 CCD25657.1 - 8.3e-58 195.5 0.0 1.7e-57 194.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25657.1 - 1.5e-21 76.6 0.0 2.2e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L11_N PF03946.9 CCD25658.1 - 6.9e-27 92.6 0.3 1e-26 92.1 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CCD25658.1 - 1.3e-25 89.2 0.7 2.2e-25 88.5 0.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain UCH PF00443.24 CCD25659.1 - 1.5e-53 181.6 3.5 1.5e-53 181.6 2.4 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCD25659.1 - 2.1e-17 63.5 1.5 2.1e-17 63.5 1.1 3.3 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Tim17 PF02466.14 CCD25661.1 - 5.8e-48 162.1 3.5 8.1e-48 161.6 2.4 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF912 PF06024.7 CCD25662.1 - 0.019 15.0 2.4 0.019 15.0 1.7 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Arm PF00514.18 CCD25663.1 - 3.3e-85 277.3 15.7 1.2e-13 50.3 0.0 8.5 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 CCD25663.1 - 2.8e-24 85.0 9.5 5.3e-24 84.2 6.6 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 CCD25663.1 - 2.1e-19 69.5 0.4 1.4e-06 28.5 0.0 5.2 1 1 5 6 6 6 5 HEAT repeats HEAT_EZ PF13513.1 CCD25663.1 - 4.7e-18 65.1 3.3 4.6e-05 23.7 0.0 6.2 6 2 1 7 7 7 4 HEAT-like repeat Arm_2 PF04826.8 CCD25663.1 - 6.7e-09 35.2 0.5 0.093 11.8 0.0 4.5 3 2 1 4 4 4 2 Armadillo-like HEAT PF02985.17 CCD25663.1 - 1e-08 34.4 0.4 0.31 11.2 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat Proteasom_PSMB PF10508.4 CCD25663.1 - 4.7e-06 25.1 0.7 0.003 15.8 0.0 2.4 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit RICTOR_V PF14668.1 CCD25663.1 - 0.00081 19.2 4.2 1.8 8.5 0.0 5.0 4 3 3 7 7 6 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 CCD25663.1 - 0.00084 19.2 0.4 7.3 6.5 0.0 4.1 2 1 2 4 4 4 1 V-ATPase subunit H Adaptin_N PF01602.15 CCD25663.1 - 0.0013 17.1 2.2 0.032 12.5 0.2 2.9 1 1 0 3 3 3 1 Adaptin N terminal region Vps35 PF03635.12 CCD25663.1 - 0.099 10.7 2.0 1.3 7.0 0.2 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting-associated protein 35 HEAT_PBS PF03130.11 CCD25663.1 - 0.21 12.1 4.5 16 6.3 0.0 4.8 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat Macoilin PF09726.4 CCD25664.1 - 2.9 6.0 23.9 3.7 5.7 16.6 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1651 PF07864.6 CCD25664.1 - 4.3 7.5 9.3 21 5.2 0.2 3.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1651) GATase_4 PF13230.1 CCD25665.1 - 2.8e-12 45.8 0.1 1.3e-09 37.1 0.0 2.3 2 1 0 2 2 2 2 Glutamine amidotransferases class-II GATase_2 PF00310.16 CCD25665.1 - 1.3e-09 37.2 0.0 1.1e-07 30.8 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCD25665.1 - 2.6e-09 37.1 0.0 1.3e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CCD25665.1 - 0.03 14.0 0.0 0.12 12.1 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferase domain Chitin_synth_1 PF01644.12 CCD25666.1 - 3.3e-73 244.8 0.3 5.7e-73 244.0 0.2 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CCD25666.1 - 3.7e-26 90.6 0.1 9.5e-26 89.3 0.1 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CCD25666.1 - 2.4e-22 79.0 0.5 2.3e-15 56.0 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CCD25666.1 - 8e-14 51.7 1.5 8e-14 51.7 1.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCD25666.1 - 1.2e-11 44.9 0.0 3.4e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 CCD25666.1 - 0.0075 15.9 0.0 0.24 11.0 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 SUR7 PF06687.7 CCD25668.1 - 5.4e-33 114.3 12.7 7.7e-33 113.8 8.8 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CCD25668.1 - 0.00041 20.0 7.3 0.00041 20.0 5.1 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Fig1 PF12351.3 CCD25668.1 - 0.17 11.7 7.4 0.3 10.9 5.1 1.3 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 DUF1625 PF07787.7 CCD25668.1 - 1.1 8.4 5.1 1.9 7.7 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) Potassium_chann PF11404.3 CCD25670.1 - 1.2 8.9 5.7 1.1 9.1 0.9 2.6 2 0 0 2 2 2 0 Potassium voltage-gated channel DUF1390 PF07150.6 CCD25670.1 - 2.6 7.3 12.5 2.1 7.6 5.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) N6_N4_Mtase PF01555.13 CCD25670.1 - 3.6 7.0 10.1 5.8 6.3 3.5 2.1 1 1 1 2 2 2 0 DNA methylase RRM_1 PF00076.17 CCD25671.1 - 8.8e-17 60.5 0.1 2.5e-12 46.2 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD25671.1 - 4.1e-05 23.4 0.0 0.013 15.4 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RAB3GAP2_N PF14655.1 CCD25671.1 - 0.016 14.2 0.6 0.031 13.2 0.4 1.4 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus YjeF_N PF03853.10 CCD25673.1 - 1.8e-35 122.0 0.0 2.2e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus ANF_receptor PF01094.23 CCD25673.1 - 0.033 12.9 0.0 0.65 8.7 0.0 2.0 1 1 1 2 2 2 0 Receptor family ligand binding region Endotoxin_C PF03944.9 CCD25673.1 - 0.083 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 delta endotoxin GBP PF02263.14 CCD25674.1 - 0.13 11.2 6.9 0.011 14.8 1.6 1.5 2 0 0 2 2 2 0 Guanylate-binding protein, N-terminal domain SMK-1 PF04802.10 CCD25675.1 - 1.4e-57 194.3 12.1 1.4e-57 194.3 8.4 3.4 4 0 0 4 4 4 1 Component of IIS longevity pathway SMK-1 adh_short_C2 PF13561.1 CCD25676.1 - 2.7e-26 92.7 0.0 3.3e-26 92.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCD25676.1 - 2.9e-20 72.8 0.6 3.9e-20 72.4 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCD25676.1 - 3.8e-08 33.1 0.1 5.8e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CCD25676.1 - 0.017 14.0 0.4 0.022 13.6 0.3 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Hydrolase_4 PF12146.3 CCD25676.1 - 0.13 12.1 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Putative lysophospholipase Rtt106 PF08512.7 CCD25677.1 - 2e-28 98.2 1.3 4.8e-28 96.9 0.9 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like RIO1 PF01163.17 CCD25678.1 - 4.3e-43 146.8 0.8 6.7e-43 146.2 0.6 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 CCD25678.1 - 1.1e-31 108.6 0.1 2.8e-31 107.4 0.1 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 CCD25678.1 - 5.7e-07 29.5 0.0 0.027 14.2 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CCD25678.1 - 0.00045 19.3 0.1 0.098 11.7 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family eIF3_p135 PF12807.2 CCD25678.1 - 0.027 14.4 0.4 0.38 10.6 0.0 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 BBS2_N PF14781.1 CCD25678.1 - 0.089 12.4 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Daxx PF03344.10 CCD25678.1 - 5.4 5.3 14.5 7.3 4.9 10.1 1.2 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 CCD25678.1 - 6.3 5.4 15.8 8.6 4.9 10.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Rick_17kDa_Anti PF05433.10 CCD25679.1 - 1.2e-08 34.4 3.9 2.6e-08 33.3 2.7 1.7 1 0 0 1 1 1 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 CCD25679.1 - 0.00025 20.7 5.0 0.00029 20.4 3.0 1.5 1 1 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 CCD25679.1 - 0.055 13.1 7.4 0.18 11.4 4.8 2.1 1 1 1 2 2 2 0 Glycine zipper TraT PF05818.7 CCD25679.1 - 0.083 12.3 0.8 0.11 11.8 0.5 1.2 1 0 0 1 1 1 0 Enterobacterial TraT complement resistance protein Gly-zipper_YMGG PF13441.1 CCD25679.1 - 1.8 8.1 8.6 4.9 6.7 5.7 1.9 1 1 0 1 1 1 0 YMGG-like Gly-zipper HSP70 PF00012.15 CCD25680.1 - 6.3e-236 784.0 8.6 7e-236 783.8 5.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCD25680.1 - 1.9e-16 59.5 0.5 6.8e-15 54.4 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CCD25680.1 - 0.0018 17.9 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF2603 PF10788.4 CCD25680.1 - 0.032 13.9 0.0 0.092 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) FtsA PF14450.1 CCD25680.1 - 0.25 11.1 8.1 1.2e+02 2.4 3.7 4.5 2 1 0 2 2 2 0 Cell division protein FtsA KH_1 PF00013.24 CCD25681.1 - 9.5e-06 25.1 0.6 1.9e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 KH domain KH_3 PF13014.1 CCD25681.1 - 1.8e-05 24.2 0.2 3.6e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 KH domain KH_2 PF07650.12 CCD25681.1 - 0.02 14.4 0.8 0.041 13.4 0.1 1.8 2 0 0 2 2 2 0 KH domain DUF2697 PF10906.3 CCD25682.1 - 7.6e-26 89.9 1.8 9e-26 89.6 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2697) VID27 PF08553.5 CCD25683.1 - 1.1e-300 999.5 12.4 1.3e-300 999.3 8.6 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein Neugrin PF06413.6 CCD25684.1 - 2.3e-09 37.4 0.3 4.2e-09 36.5 0.2 1.4 1 0 0 1 1 1 1 Neugrin HTH_11 PF08279.7 CCD25684.1 - 6.7e-05 22.4 0.0 0.0022 17.6 0.0 2.3 2 0 0 2 2 2 1 HTH domain Sigma70_r4 PF04545.11 CCD25684.1 - 0.00024 20.3 0.1 0.00042 19.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 Mod_r PF07200.8 CCD25684.1 - 0.015 15.2 0.9 0.02 14.8 0.6 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein HTH_24 PF13412.1 CCD25684.1 - 0.023 14.0 0.0 0.066 12.6 0.0 1.8 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF1138 PF06592.8 CCD25684.1 - 0.035 14.1 0.1 0.063 13.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1138) MarR_2 PF12802.2 CCD25684.1 - 0.046 13.4 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 MarR family HTH_23 PF13384.1 CCD25684.1 - 0.048 13.3 0.3 0.99 9.1 0.0 2.5 2 0 0 2 2 2 0 Homeodomain-like domain DUF4019 PF13211.1 CCD25684.1 - 0.063 13.5 1.0 0.1 12.8 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4019) MarR PF01047.17 CCD25684.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 MarR family HTH_32 PF13565.1 CCD25684.1 - 0.075 13.8 1.0 0.33 11.7 0.1 2.3 2 0 0 2 2 2 0 Homeodomain-like domain HTH_AsnC-type PF13404.1 CCD25684.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MRP-L20 PF12824.2 CCD25684.1 - 0.45 10.4 5.6 1.1 9.1 3.7 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein subunit L20 WTX PF09422.5 CCD25684.1 - 0.5 9.2 2.9 0.49 9.2 2.0 1.1 1 0 0 1 1 1 0 WTX protein Syntaxin-6_N PF09177.6 CCD25685.1 - 0.038 14.4 1.0 0.078 13.3 0.7 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal LIM_bind PF01803.11 CCD25686.1 - 1.7e-30 105.9 5.4 1.7e-30 105.9 3.7 2.6 3 1 0 3 3 3 1 LIM-domain binding protein Rap1-DNA-bind PF09197.5 CCD25687.1 - 1e-43 148.1 18.0 3.8e-41 139.8 0.2 3.6 3 0 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.3 CCD25687.1 - 1.3e-23 82.6 0.1 7.9e-23 80.1 0.0 2.5 3 0 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-binding PF00249.26 CCD25687.1 - 1.6e-07 31.2 0.2 4.8e-06 26.5 0.0 3.5 4 0 0 4 4 4 1 Myb-like DNA-binding domain BRCT PF00533.21 CCD25687.1 - 0.003 17.6 0.0 0.01 15.9 0.0 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA_23 PF13476.1 CCD25687.1 - 0.43 10.8 20.2 0.46 10.7 11.8 2.4 2 0 0 2 2 2 0 AAA domain PAT1 PF09770.4 CCD25687.1 - 3.3 5.8 44.8 5.9 4.9 31.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Metallophos PF00149.23 CCD25688.1 - 4.7e-08 32.6 3.3 5.5e-08 32.4 2.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MgsA_C PF12002.3 CCD25689.1 - 2.7e-52 176.8 0.1 7.2e-52 175.4 0.1 1.7 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 CCD25689.1 - 2.3e-15 56.9 0.1 7.5e-15 55.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCD25689.1 - 7.3e-14 51.3 0.0 2.4e-12 46.4 0.0 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCD25689.1 - 3.4e-09 36.6 0.0 9.8e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCD25689.1 - 1.1e-06 28.7 1.4 7.8e-06 26.0 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCD25689.1 - 1.5e-06 28.3 0.4 0.0011 18.9 0.0 2.6 1 1 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CCD25689.1 - 4.9e-06 26.3 0.0 1.9e-05 24.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 CCD25689.1 - 0.00011 21.6 0.0 0.0012 18.3 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 CCD25689.1 - 0.00033 19.8 0.2 0.6 9.2 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CCD25689.1 - 0.0052 16.2 0.0 0.0091 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 CCD25689.1 - 0.012 15.9 0.0 0.036 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CCD25689.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCD25689.1 - 0.025 14.8 0.0 0.075 13.3 0.0 1.9 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 CCD25689.1 - 0.031 15.0 0.0 0.12 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CCD25689.1 - 0.032 13.6 0.5 4.2 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA-like domain AAA_2 PF07724.9 CCD25689.1 - 0.04 13.8 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 CCD25689.1 - 0.054 13.5 0.0 0.38 10.7 0.0 2.3 2 1 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 CCD25689.1 - 0.055 12.8 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCD25689.1 - 0.066 13.4 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Glyco_transf_22 PF03901.12 CCD25690.1 - 5.9e-89 298.9 31.4 7e-89 298.7 21.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Adenylsucc_synt PF00709.16 CCD25691.1 - 4.1e-164 546.2 0.0 4.6e-164 546.0 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Ribosomal_L37ae PF01780.14 CCD25692.1 - 2.5e-39 133.0 8.3 2.8e-39 132.8 5.8 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rep_fac-A_C PF08646.5 CCD25692.1 - 0.0013 18.4 0.6 0.0015 18.2 0.4 1.2 1 0 0 1 1 1 1 Replication factor-A C terminal domain Zn_Tnp_IS1595 PF12760.2 CCD25692.1 - 0.0085 15.8 2.6 0.013 15.2 1.8 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-H2C2_2 PF13465.1 CCD25692.1 - 0.012 15.8 0.7 1.1 9.6 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Sgf11 PF08209.6 CCD25692.1 - 0.036 13.3 1.1 0.49 9.7 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) DUF1364 PF07102.7 CCD25692.1 - 0.06 13.2 0.9 0.077 12.8 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) OrfB_Zn_ribbon PF07282.6 CCD25692.1 - 0.094 12.3 3.4 0.12 11.9 2.4 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain CarbpepA_inh PF02977.10 CCD25692.1 - 0.13 11.8 2.8 0.41 10.2 0.2 2.2 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Elf1 PF05129.8 CCD25692.1 - 0.17 11.5 3.6 0.48 10.1 2.5 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like A2L_zn_ribbon PF08792.5 CCD25692.1 - 0.22 11.0 3.4 7.8 6.0 0.4 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain C1_1 PF00130.17 CCD25692.1 - 0.22 11.2 2.0 0.33 10.7 1.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-BED PF02892.10 CCD25692.1 - 0.31 10.8 5.3 1.6 8.5 0.3 2.3 1 1 1 2 2 2 0 BED zinc finger zf-C4_ClpX PF06689.8 CCD25692.1 - 2.2 7.8 5.8 5.9 6.4 4.0 1.9 1 1 0 1 1 1 0 ClpX C4-type zinc finger POP1 PF06978.6 CCD25693.1 - 4e-66 222.2 12.2 4e-66 222.2 8.4 2.0 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 CCD25693.1 - 8.4e-31 105.6 1.5 8.4e-31 105.6 1.0 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain Ssu72 PF04722.8 CCD25694.1 - 3.9e-88 293.8 0.0 4.5e-88 293.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Peptidase_C54 PF03416.14 CCD25695.1 - 2.6e-88 295.7 0.0 3.3e-88 295.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 G-patch PF01585.18 CCD25696.1 - 1.7e-09 37.3 3.6 5.5e-09 35.6 2.5 2.0 1 0 0 1 1 1 1 G-patch domain SID PF11778.3 CCD25697.1 - 6.3e-25 87.6 1.2 6.3e-25 87.6 0.8 2.8 2 1 0 2 2 2 1 Septation initiation Tropomyosin_1 PF12718.2 CCD25697.1 - 1.6e-06 27.9 15.2 1.6e-06 27.9 10.5 3.5 2 1 1 3 3 3 2 Tropomyosin like Hemerythrin PF01814.18 CCD25697.1 - 0.084 13.0 6.7 7.7 6.6 2.6 2.8 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF3584 PF12128.3 CCD25697.1 - 0.74 7.0 33.2 0.63 7.2 11.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) IncA PF04156.9 CCD25697.1 - 3.5 7.1 45.9 0.87 9.1 6.6 3.1 2 1 1 3 3 3 0 IncA protein ERM PF00769.14 CCD25697.1 - 5.8 6.3 48.0 0.072 12.6 8.8 3.4 3 1 0 3 3 3 0 Ezrin/radixin/moesin family Syntaxin-6_N PF09177.6 CCD25697.1 - 9.1 6.7 28.8 0.99 9.8 3.1 4.2 2 2 2 4 4 4 0 Syntaxin 6, N-terminal DnaJ PF00226.26 CCD25698.1 - 2.8e-26 91.0 0.3 2.8e-26 91.0 0.2 2.4 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 CCD25698.1 - 1.2e-07 31.6 6.3 1.2e-07 31.6 4.4 2.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CCD25698.1 - 1.2e-07 31.7 6.3 0.00031 20.7 0.3 2.9 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 CCD25698.1 - 6.5e-06 26.1 10.9 0.00018 21.5 2.8 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 CCD25698.1 - 1.6e-05 24.9 9.6 0.027 14.7 0.4 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD25698.1 - 0.00017 21.6 2.2 0.19 12.1 0.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger AKAP95 PF04988.7 CCD25698.1 - 0.0043 16.8 2.3 0.0043 16.8 1.6 3.4 3 0 0 3 3 3 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.1 CCD25698.1 - 0.011 15.5 14.6 0.073 12.9 1.4 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-UBP PF02148.14 CCD25698.1 - 0.05 13.7 0.2 1.2 9.2 0.1 2.5 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein GST_C PF00043.20 CCD25699.1 - 3.2e-20 71.9 0.0 6.9e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCD25699.1 - 4.5e-17 61.9 0.0 9.2e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCD25699.1 - 2e-09 37.3 0.0 4.2e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCD25699.1 - 5.5e-09 36.1 0.0 1.1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCD25699.1 - 0.0012 18.6 0.0 0.0021 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCD25699.1 - 0.051 14.0 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4045 PF13254.1 CCD25699.1 - 3.4 6.8 12.1 4.9 6.3 8.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Elongin_A PF06881.6 CCD25700.1 - 9.6e-18 64.5 14.1 4e-15 56.1 0.2 3.1 2 1 1 3 3 3 2 RNA polymerase II transcription factor SIII (Elongin) subunit A CRAL_TRIO PF00650.15 CCD25701.1 - 2.8e-40 137.4 0.0 4.3e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCD25701.1 - 5.8e-10 39.1 0.6 3.2e-09 36.7 0.4 2.4 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain EXOSC1 PF10447.4 CCD25702.1 - 3.4e-33 113.4 0.1 7.8e-33 112.2 0.1 1.6 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 Globin PF00042.17 CCD25704.1 - 0.014 15.7 0.0 0.052 13.9 0.0 2.0 1 1 0 1 1 1 0 Globin SNF5 PF04855.7 CCD25704.1 - 0.094 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 Med16 PF11635.3 CCD25705.1 - 1.8e-189 631.3 9.1 2.1e-189 631.1 6.3 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Ytp1 PF10355.4 CCD25706.1 - 4e-78 262.3 18.3 7.9e-78 261.3 12.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) Peptidase_S8 PF00082.17 CCD25707.1 - 4.4e-57 193.3 3.4 4.4e-57 193.3 2.4 1.6 2 0 0 2 2 2 1 Subtilase family P_proprotein PF01483.15 CCD25707.1 - 1.8e-25 88.4 1.2 4.2e-25 87.3 0.8 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF1049 PF06305.6 CCD25707.1 - 0.22 11.0 0.3 0.43 10.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Peptidase_C1_2 PF03051.10 CCD25708.1 - 4.3e-160 533.0 4.4 4.8e-160 532.8 3.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 CCD25708.1 - 8.8e-08 32.2 1.0 0.0046 16.8 0.0 2.8 2 1 0 2 2 2 2 Papain family cysteine protease PSD2 PF07624.6 CCD25708.1 - 0.067 12.8 0.6 0.23 11.1 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Fe_hyd_lg_C PF02906.9 CCD25709.1 - 1e-56 192.3 0.0 1.5e-56 191.7 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain G6PD_C PF02781.11 CCD25710.1 - 2.5e-126 420.4 0.0 3.4e-126 420.0 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CCD25710.1 - 1.4e-63 214.4 0.1 2.3e-63 213.7 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain ATG2_CAD PF13329.1 CCD25711.1 - 4.1e-31 107.6 0.7 4.1e-31 107.6 0.5 3.2 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 CCD25711.1 - 6.2e-30 103.2 0.1 1.7e-29 101.8 0.1 1.8 1 0 0 1 1 1 1 ATG C terminal domain Etmic-2 PF06670.6 CCD25711.1 - 0.097 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 ANTH PF07651.11 CCD25712.1 - 6.1e-69 231.8 0.0 6.1e-69 231.8 0.0 2.8 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.12 CCD25712.1 - 1.4e-57 193.9 3.1 1.4e-57 193.9 2.2 5.0 3 2 2 5 5 5 1 I/LWEQ domain ENTH PF01417.15 CCD25712.1 - 0.00047 20.0 3.2 0.00047 20.0 0.0 2.6 2 1 0 2 2 2 1 ENTH domain Med15 PF09606.5 CCD25712.1 - 0.41 8.8 41.7 0.62 8.1 28.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SUI1 PF01253.17 CCD25713.1 - 3.9e-28 97.0 1.1 5.1e-28 96.6 0.8 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Cir_N PF10197.4 CCD25714.1 - 8.7e-13 48.0 14.0 8.7e-13 48.0 9.7 2.3 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.3 CCD25714.1 - 4.6e-11 43.0 8.3 4.6e-11 43.0 5.7 2.3 1 1 1 2 2 2 1 Pre-mRNA splicing factor Myc_target_1 PF15179.1 CCD25714.1 - 0.12 11.9 1.9 0.16 11.5 1.3 1.2 1 0 0 1 1 1 0 Myc target protein 1 NAP PF00956.13 CCD25715.1 - 3.7e-20 72.0 9.4 3.7e-20 72.0 6.5 1.9 2 1 0 2 2 2 1 Nucleosome assembly protein (NAP) tRNA-synt_1e PF01406.14 CCD25716.1 - 1.1e-139 464.7 0.9 2.3e-139 463.6 0.7 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CCD25716.1 - 3.4e-09 35.8 2.0 9.8e-07 27.7 0.2 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CCD25716.1 - 1.1e-05 23.6 0.0 3.3e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1f PF01921.13 CCD25716.1 - 0.0059 15.3 0.4 0.027 13.1 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetases class I (K) DUF4105 PF13387.1 CCD25716.1 - 0.021 13.9 0.1 0.043 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) RNA_pol_I_A49 PF06870.7 CCD25717.1 - 1e-132 442.3 1.4 1.2e-132 442.1 1.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor AAA_23 PF13476.1 CCD25718.1 - 2.9e-29 102.8 2.9 2.9e-29 102.8 2.0 8.8 2 1 3 5 5 2 1 AAA domain SMC_N PF02463.14 CCD25718.1 - 7.4e-17 61.3 4.7 9.1e-11 41.4 1.1 4.1 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain Rad50_zn_hook PF04423.9 CCD25718.1 - 1.3e-12 46.9 0.3 1.3e-12 46.9 0.2 6.6 6 0 0 6 6 5 1 Rad50 zinc hook motif AAA_13 PF13166.1 CCD25718.1 - 2.3e-12 46.2 142.6 0.00022 19.8 0.1 6.5 2 1 3 5 5 5 4 AAA domain SbcCD_C PF13558.1 CCD25718.1 - 1.1e-11 44.5 0.0 3e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.1 CCD25718.1 - 1.5e-07 31.6 8.2 0.0004 20.4 0.0 6.5 3 2 2 6 6 5 2 AAA domain Laminin_I PF06008.9 CCD25718.1 - 0.00014 21.3 10.4 0.00014 21.3 7.2 7.1 3 2 3 6 6 5 1 Laminin Domain I AAA_29 PF13555.1 CCD25718.1 - 0.00071 19.0 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CCD25718.1 - 0.03 14.6 0.1 0.03 14.6 0.1 8.6 4 3 3 7 7 6 0 ABC transporter Filament PF00038.16 CCD25718.1 - 0.031 13.7 118.8 0.17 11.3 7.2 7.7 1 1 5 7 7 7 0 Intermediate filament protein Reo_sigmaC PF04582.7 CCD25718.1 - 0.087 11.9 49.3 0.032 13.4 1.4 7.0 3 2 4 8 8 8 0 Reovirus sigma C capsid protein AAA_19 PF13245.1 CCD25718.1 - 0.25 11.0 0.1 0.64 9.8 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_16 PF13191.1 CCD25718.1 - 0.69 9.8 0.0 0.69 9.8 0.0 3.8 4 0 0 4 4 4 0 AAA ATPase domain RRM_1 PF00076.17 CCD25719.1 - 2.6e-05 23.7 0.0 5.4e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD25719.1 - 3.8e-05 23.5 0.0 9.7e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.3 CCD25719.1 - 7.9e-05 22.3 1.9 0.00014 21.4 0.3 2.2 2 1 0 2 2 2 1 CTD kinase subunit gamma CTK3 RRM_5 PF13893.1 CCD25719.1 - 0.0031 17.3 0.1 0.0071 16.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spo7_2_N PF15407.1 CCD25719.1 - 0.0045 16.4 0.0 0.014 14.8 0.0 1.9 1 0 0 1 1 1 1 Sporulation protein family 7 SpoVIF PF14069.1 CCD25719.1 - 0.034 13.8 3.6 7.3 6.4 0.2 3.7 4 0 0 4 4 4 0 Stage VI sporulation protein F SH2 PF00017.19 CCD25719.1 - 0.073 12.8 1.0 0.93 9.3 0.0 2.8 2 0 0 2 2 2 0 SH2 domain MRP-L46 PF11788.3 CCD25720.1 - 3e-29 101.9 0.0 4.8e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 Mg296 PF09644.5 CCD25720.1 - 0.2 11.4 1.9 2.6 7.9 0.1 2.2 2 0 0 2 2 2 0 Mg296 protein WD40 PF00400.27 CCD25721.1 - 8.2e-21 73.0 8.7 8.9e-08 31.7 0.8 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Hira PF07569.6 CCD25721.1 - 0.11 11.6 4.0 1.3 8.2 0.0 3.3 3 0 0 3 3 3 0 TUP1-like enhancer of split Hyphal_reg_CWP PF11765.3 CCD25723.1 - 5.2e-09 35.3 8.0 5.2e-09 35.3 5.5 3.3 2 2 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal RTC4 PF14474.1 CCD25725.1 - 2.3e-30 105.0 0.1 4.8e-30 104.0 0.1 1.6 1 0 0 1 1 1 1 RTC4-like domain DUF1151 PF06625.6 CCD25725.1 - 0.19 11.4 4.3 0.092 12.4 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) zf-CCHC PF00098.18 CCD25726.1 - 1.2e-56 186.1 52.9 7.4e-09 35.1 1.3 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 CCD25726.1 - 1.1e-11 44.1 43.1 0.0051 16.4 0.4 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 CCD25726.1 - 7.4e-10 38.1 48.7 0.0096 15.3 2.1 7.1 2 2 5 7 7 7 5 Zinc knuckle zf-CCHC_3 PF13917.1 CCD25726.1 - 1.1e-07 31.4 45.3 0.23 11.2 0.7 7.0 2 2 5 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.1 CCD25726.1 - 0.14 11.8 40.5 0.14 11.8 0.6 7.0 7 0 0 7 7 7 0 Zinc knuckle Pterin_bind PF00809.17 CCD25727.1 - 1.6e-44 151.8 0.0 2.3e-43 147.9 0.0 2.3 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 CCD25727.1 - 2.4e-39 133.9 0.0 1e-38 131.9 0.0 2.1 2 0 0 2 2 2 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 CCD25727.1 - 1.6e-37 128.0 0.7 1.6e-17 63.6 0.0 2.5 2 0 0 2 2 2 2 Dihydroneopterin aldolase PH PF00169.24 CCD25728.1 - 1.5e-08 34.7 5.8 1.8e-08 34.5 0.0 3.7 3 1 0 3 3 3 1 PH domain Dsl1_C PF11989.3 CCD25729.1 - 1.1e-100 336.5 17.6 1.1e-100 336.5 12.2 3.0 3 0 0 3 3 3 1 Retrograde transport protein Dsl1 C terminal Dsl1_N PF11988.3 CCD25729.1 - 4e-88 295.6 32.8 9.9e-88 294.3 22.8 1.7 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 N terminal HMA PF00403.21 CCD25730.1 - 1e-11 44.8 0.2 1.1e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Yae1_N PF09811.4 CCD25731.1 - 1.6e-09 37.1 0.8 1.6e-09 37.1 0.5 1.8 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Fib_alpha PF08702.5 CCD25731.1 - 0.048 13.7 0.5 0.066 13.3 0.3 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4191 PF13829.1 CCD25731.1 - 0.15 11.1 0.2 0.19 10.7 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF1744 PF08490.7 CCD25732.1 - 1.7e-147 491.1 8.3 3.1e-147 490.3 5.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CCD25732.1 - 5.8e-68 229.1 4.7 5.8e-68 229.1 3.3 2.1 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CCD25732.1 - 1.1e-21 77.2 3.4 2.5e-21 76.0 2.4 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CCD25732.1 - 4.1e-09 36.2 2.5 1.2e-08 34.7 0.2 2.9 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB YIF1 PF03878.10 CCD25733.1 - 8.5e-72 241.1 6.0 1.2e-71 240.6 4.2 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 CCD25733.1 - 0.03 13.8 8.8 0.069 12.6 6.1 1.7 1 1 0 1 1 1 0 Yip1 domain CRAL_TRIO PF00650.15 CCD25734.1 - 1.2e-39 135.3 0.0 1.9e-39 134.7 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCD25734.1 - 5e-11 42.5 0.2 1.8e-10 40.7 0.1 2.0 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCD25734.1 - 7.7e-06 25.8 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Ist1 PF03398.9 CCD25735.1 - 5.5e-54 182.0 3.2 5.5e-54 182.0 2.2 1.7 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway PI3_PI4_kinase PF00454.22 CCD25736.1 - 8.7e-31 107.1 0.0 2.7e-30 105.6 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 CCD25736.1 - 6.9e-19 67.3 1.0 5.4e-18 64.4 0.1 2.7 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 CCD25736.1 - 1.3e-05 24.5 0.6 3.5e-05 23.0 0.4 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF148 PF02520.12 CCD25736.1 - 0.011 15.5 3.2 0.014 15.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 PLAT PF01477.18 CCD25736.1 - 0.046 14.0 1.7 0.11 12.8 0.0 2.4 2 0 0 2 2 2 0 PLAT/LH2 domain AA_permease PF00324.16 CCD25737.1 - 1.1e-126 423.0 51.8 1.4e-126 422.7 35.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD25737.1 - 1.1e-31 109.8 61.0 1.9e-31 109.0 42.1 1.5 1 1 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.3 CCD25737.1 - 0.02 14.2 1.8 1.3 8.4 0.3 3.2 2 0 0 2 2 2 0 Intrinsic membrane protein PufX FlxA PF14282.1 CCD25737.1 - 0.57 10.1 5.3 0.87 9.5 3.7 1.1 1 0 0 1 1 1 0 FlxA-like protein AA_permease PF00324.16 CCD25738.1 - 1.3e-125 419.4 51.1 1.5e-125 419.2 35.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD25738.1 - 4.9e-31 107.7 56.4 6.8e-31 107.2 39.1 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCD25739.1 - 3.8e-15 55.2 1.7 4.8e-15 54.8 1.2 1.1 1 0 0 1 1 1 1 Amino acid permease FH2 PF02181.18 CCD25740.1 - 5.5e-88 295.3 8.4 5.5e-88 295.3 5.9 5.0 2 1 4 6 6 6 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 CCD25740.1 - 4e-45 153.6 4.5 4e-45 153.6 3.1 4.4 5 0 0 5 5 5 2 Diaphanous FH3 Domain Drf_GBD PF06371.8 CCD25740.1 - 1.3e-26 93.0 9.6 1.3e-26 93.0 6.6 5.8 5 2 0 5 5 5 1 Diaphanous GTPase-binding Domain Sec2p PF06428.6 CCD25741.1 - 1.9e-23 82.2 11.6 1.9e-23 82.2 8.1 2.9 1 1 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF2552 PF10827.3 CCD25741.1 - 0.015 15.2 0.4 0.06 13.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) ICAT PF06384.6 CCD25741.1 - 0.84 9.4 0.0 0.84 9.4 0.0 3.5 4 0 0 4 4 4 0 Beta-catenin-interacting protein ICAT ArfGap PF01412.13 CCD25741.1 - 1.3 8.7 5.0 0.44 10.3 0.0 2.8 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf TIMELESS PF04821.9 CCD25742.1 - 3.7e-48 164.0 2.9 3.7e-48 164.0 2.0 2.8 2 1 0 2 2 2 1 Timeless protein Hjc PF01870.13 CCD25742.1 - 0.12 12.0 1.0 0.64 9.6 0.2 2.4 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) 2-Hacid_dh_C PF02826.14 CCD25743.1 - 2.1e-54 183.3 0.0 3.8e-54 182.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCD25743.1 - 2.1e-13 49.8 0.0 2.8e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCD25743.1 - 8.4e-05 22.4 0.0 0.00026 20.8 0.0 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 CCD25743.1 - 0.001 19.1 0.0 0.0038 17.3 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 CCD25743.1 - 0.0081 15.5 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AgrD PF05931.6 CCD25743.1 - 0.24 11.0 0.8 0.46 10.1 0.6 1.5 1 0 0 1 1 1 0 Staphylococcal AgrD protein HCO3_cotransp PF00955.16 CCD25744.1 - 5.7e-57 193.5 14.4 1.7e-34 119.4 2.6 2.1 1 1 1 2 2 2 2 HCO3- transporter family BacA PF02673.13 CCD25744.1 - 1.4 8.0 12.9 1.9 7.6 0.6 3.6 3 1 1 4 4 4 0 Bacitracin resistance protein BacA Abhydrolase_1 PF00561.15 CCD25745.1 - 4.4e-65 219.4 0.0 4.7e-64 216.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCD25745.1 - 5.3e-12 46.1 0.0 1.1e-10 41.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCD25745.1 - 0.0013 18.4 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family PH PF00169.24 CCD25746.1 - 2e-09 37.5 0.3 6.4e-06 26.3 0.0 2.8 2 0 0 2 2 2 2 PH domain Herpes_gE PF02480.11 CCD25747.1 - 0.019 13.2 0.1 0.29 9.3 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E TMEM220 PF15071.1 CCD25747.1 - 0.11 12.8 2.2 0.43 11.0 0.0 3.0 3 0 0 3 3 3 0 Transmembrane family 220, helix EMG1 PF03587.9 CCD25748.1 - 2e-75 252.5 0.0 2.4e-75 252.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase LCD1 PF09798.4 CCD25749.1 - 8.9e-191 635.2 47.9 1.3e-190 634.6 33.2 1.2 1 0 0 1 1 1 1 DNA damage checkpoint protein DsrD PF08679.6 CCD25749.1 - 0.046 13.7 0.3 6.3 6.8 0.0 3.3 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) DUF4140 PF13600.1 CCD25749.1 - 1.1 9.7 5.3 8.1 6.9 0.6 2.9 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Ribosomal_L37e PF01907.14 CCD25750.1 - 1.1e-26 92.3 12.7 1.1e-26 92.3 8.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 CCD25750.1 - 0.00093 18.9 1.8 0.0014 18.3 1.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 CCD25750.1 - 0.0081 15.8 0.4 0.01 15.4 0.2 1.4 1 1 0 1 1 1 1 SelR domain zinc_ribbon_6 PF14599.1 CCD25750.1 - 0.15 11.8 1.7 0.23 11.3 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon zf-C3HC4_2 PF13923.1 CCD25750.1 - 1.5 8.9 4.3 2.3 8.3 3.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FHA PF00498.21 CCD25751.1 - 0.00019 21.4 0.0 0.0008 19.4 0.0 2.1 1 0 0 1 1 1 1 FHA domain S-AdoMet_synt_C PF02773.11 CCD25752.1 - 7.1e-75 249.3 0.2 1.2e-74 248.5 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CCD25752.1 - 5.1e-46 155.5 0.0 1e-45 154.5 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CCD25752.1 - 1.3e-43 147.2 0.2 1.3e-43 147.2 0.1 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain PAP2 PF01569.16 CCD25753.1 - 2e-20 72.7 0.5 2e-20 72.7 0.4 1.7 2 0 0 2 2 2 1 PAP2 superfamily DUF3169 PF11368.3 CCD25753.1 - 2.7 7.1 8.4 0.11 11.7 0.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) FUSC_2 PF13515.1 CCD25753.1 - 7.3 6.5 12.0 0.059 13.3 1.2 2.5 2 1 0 2 2 2 0 Fusaric acid resistance protein-like PSP1 PF04468.7 CCD25754.1 - 1.2e-32 111.7 0.7 3.5e-32 110.2 0.5 1.9 1 0 0 1 1 1 1 PSP1 C-terminal conserved region TrkA_C PF02080.16 CCD25754.1 - 0.16 11.5 0.0 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 TrkA-C domain Oxidored_FMN PF00724.15 CCD25755.1 - 1.3e-28 100.0 0.0 1.9e-27 96.1 0.0 2.1 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AA_permease PF00324.16 CCD25757.1 - 2e-124 415.5 37.9 2.3e-124 415.3 26.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD25757.1 - 3.2e-29 101.7 34.4 3.9e-29 101.4 23.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUP PF00674.13 CCD25758.1 - 2.5e-21 75.6 4.1 5.9e-21 74.4 2.8 1.7 1 1 0 1 1 1 1 DUP family DUF4131 PF13567.1 CCD25758.1 - 0.0018 17.7 1.7 0.0029 17.0 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) Tetraspannin PF00335.15 CCD25758.1 - 0.0039 16.4 1.9 0.0055 16.0 1.3 1.2 1 0 0 1 1 1 1 Tetraspanin family IncA PF04156.9 CCD25758.1 - 0.13 11.8 0.2 0.18 11.3 0.2 1.2 1 0 0 1 1 1 0 IncA protein VIT1 PF01988.14 CCD25758.1 - 1.2 8.5 3.9 1.7 8.0 2.7 1.1 1 0 0 1 1 1 0 VIT family La PF05383.12 CCD25759.1 - 9.2e-17 60.6 0.1 2.2e-16 59.3 0.1 1.7 1 0 0 1 1 1 1 La domain DUF1779 PF08680.5 CCD25760.1 - 0.021 14.7 1.3 0.037 13.8 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) RNase_T PF00929.19 CCD25760.1 - 0.12 12.7 0.0 0.42 10.8 0.0 2.0 1 0 0 1 1 1 0 Exonuclease Glutaredoxin PF00462.19 CCD25761.1 - 9.1e-15 54.3 0.0 1.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 CCD25761.1 - 6.8e-05 22.4 0.3 0.00014 21.4 0.2 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 CCD25761.1 - 0.00086 19.0 0.3 0.0019 17.9 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.1 CCD25761.1 - 0.0022 17.9 1.5 0.56 10.1 0.3 2.3 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.1 CCD25761.1 - 0.0048 16.8 0.0 0.0096 15.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CCD25761.1 - 0.0064 16.6 0.0 0.009 16.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain DSBA PF01323.15 CCD25761.1 - 0.017 14.7 0.4 0.22 11.0 0.1 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain DUF1904 PF08921.6 CCD25761.1 - 0.017 15.1 0.6 0.13 12.2 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1904) DUF953 PF06110.6 CCD25761.1 - 0.054 12.9 0.2 0.097 12.1 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 CCD25761.1 - 0.069 12.8 0.1 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.1 CCD25761.1 - 0.084 12.3 0.2 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 F plasmid transfer operon protein Glyco_hydro_2_N PF02837.13 CCD25761.1 - 0.087 12.3 0.1 0.29 10.6 0.0 1.8 1 1 1 2 2 2 0 Glycosyl hydrolases family 2, sugar binding domain DUF836 PF05768.9 CCD25761.1 - 0.12 12.6 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Ribosomal_L33 PF00471.15 CCD25761.1 - 0.12 12.5 0.4 0.12 12.5 0.3 1.7 2 0 0 2 2 2 0 Ribosomal protein L33 DUF3128 PF11326.3 CCD25762.1 - 5.8e-30 103.2 2.6 6.6e-30 103.0 1.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Complex1_LYR PF05347.10 CCD25763.1 - 1.6e-10 40.5 0.0 8.1e-10 38.3 0.0 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCD25763.1 - 1.2e-09 38.1 0.0 3.2e-09 36.8 0.0 1.7 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CCD25763.1 - 3.2e-06 27.5 0.2 4.5e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF4028 PF13220.1 CCD25763.1 - 0.074 12.6 0.2 0.31 10.7 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4028) PMT_C PF11647.3 CCD25763.1 - 0.17 11.5 1.3 1.8 8.2 0.1 2.2 2 0 0 2 2 2 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Hexokinase_2 PF03727.11 CCD25764.1 - 1.3e-83 279.9 0.0 1.8e-83 279.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCD25764.1 - 5.9e-68 228.2 0.1 9.2e-68 227.6 0.1 1.3 1 0 0 1 1 1 1 Hexokinase GRASP55_65 PF04495.9 CCD25765.1 - 1.5e-34 118.9 0.0 3.1e-33 114.6 0.0 2.2 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain Thioredoxin PF00085.15 CCD25766.1 - 9e-35 118.5 0.7 7.4e-20 70.5 0.0 3.8 5 0 0 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.1 CCD25766.1 - 8.5e-16 58.2 1.6 2.7e-13 50.1 0.2 3.6 3 1 0 3 3 3 2 Thioredoxin-like domain FKBP_C PF00254.23 CCD25767.1 - 3.3e-33 113.5 0.0 4e-33 113.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Zn_clus PF00172.13 CCD25768.1 - 1e-05 25.3 6.1 1.9e-05 24.4 4.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LOH1CR12 PF10158.4 CCD25768.1 - 0.0016 18.2 0.1 1.5 8.6 0.0 2.7 2 0 0 2 2 2 2 Tumour suppressor protein MH2 PF03166.9 CCD25768.1 - 0.0088 15.8 0.1 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 MH2 domain DUF4472 PF14739.1 CCD25768.1 - 0.019 15.4 1.0 0.058 13.8 0.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) Angiomotin_C PF12240.3 CCD25768.1 - 0.73 9.2 6.9 0.2 11.1 0.1 2.3 2 0 0 2 2 2 0 Angiomotin C terminal Recep_L_domain PF01030.19 CCD25769.1 - 9.9e-08 31.9 16.8 0.0019 18.1 0.1 4.6 1 1 4 5 5 5 4 Receptor L domain Pkinase PF00069.20 CCD25770.1 - 5.5e-68 228.9 0.0 1.3e-67 227.7 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25770.1 - 5.4e-49 166.5 0.0 7.8e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD25770.1 - 1e-07 31.2 0.0 1.9e-06 27.0 0.0 2.1 2 0 0 2 2 2 1 Kinase-like UL97 PF06734.7 CCD25770.1 - 0.034 13.5 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 UL97 ArfGap PF01412.13 CCD25771.1 - 1.6e-28 98.7 7.5 1.6e-28 98.7 5.2 2.7 1 1 1 2 2 2 1 Putative GTPase activating protein for Arf RSF PF14876.1 CCD25772.1 - 4.7e-12 45.3 3.0 4.7e-12 45.3 2.1 1.9 3 0 0 3 3 3 1 Respiratory growth transcriptional regulator Glyco_transf_8C PF08437.5 CCD25772.1 - 0.46 10.5 0.0 0.46 10.5 0.0 3.2 4 0 0 4 4 4 0 Glycosyl transferase family 8 C-terminal DUP PF00674.13 CCD25773.1 - 1.6e-21 76.2 4.0 3.1e-21 75.3 2.8 1.5 1 1 0 1 1 1 1 DUP family T_cell_tran_alt PF15128.1 CCD25774.1 - 0.15 11.5 0.2 0.18 11.2 0.2 1.1 1 0 0 1 1 1 0 T-cell leukemia translocation-altered QCR10 PF09796.4 CCD25774.1 - 0.18 11.4 4.0 0.3 10.7 2.8 1.4 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Pmp3 PF01679.12 CCD25775.1 - 1.5e-22 79.0 7.0 1.8e-22 78.7 4.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RPAP1_C PF08620.5 CCD25776.1 - 1.6e-29 101.5 0.0 4.8e-29 100.0 0.0 1.9 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 CCD25776.1 - 6.1e-12 44.9 8.4 9.3e-12 44.3 4.6 2.2 2 0 0 2 2 2 1 RPAP1-like, N-terminal Ret_tiss PF10044.4 CCD25776.1 - 1.8 9.1 5.2 12 6.4 0.6 3.3 3 0 0 3 3 3 0 Retinal tissue protein Adeno_PIX PF03955.9 CCD25777.1 - 5.8 7.4 6.0 9.7 6.7 0.1 3.1 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) Fumble PF03630.9 CCD25778.1 - 5.5e-118 393.7 18.6 1.4e-114 382.4 10.4 3.2 1 1 1 2 2 2 2 Fumble T4SS PF07996.6 CCD25778.1 - 1.2 8.9 14.9 0.18 11.6 1.3 3.0 2 1 1 3 3 3 0 Type IV secretion system proteins Pex14_N PF04695.8 CCD25778.1 - 1.4 8.9 5.6 6.6 6.7 0.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ATP_transf PF09830.4 CCD25779.1 - 3.5e-18 65.1 0.0 6.1e-18 64.3 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase UCR_14kD PF02271.11 CCD25780.1 - 5.3e-42 141.8 0.1 6.1e-42 141.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Endonuclease_NS PF01223.18 CCD25783.1 - 2.5e-56 190.5 0.0 3.3e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease HEAT PF02985.17 CCD25784.1 - 0.023 14.7 0.1 1.8 8.8 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat Sec10 PF07393.6 CCD25785.1 - 2e-53 181.6 22.3 2.6e-53 181.2 15.5 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 DUF4413 PF14372.1 CCD25789.2 - 0.18 11.7 0.2 15 5.6 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4413) RRM_1 PF00076.17 CCD25790.2 - 1.4e-07 31.0 0.1 2.2e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CCD25790.2 - 2.3e-06 27.9 2.1 4.6e-06 26.9 1.4 1.6 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 CCD25790.2 - 4.5e-05 23.2 0.1 7.1e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD25790.2 - 4.6e-05 23.3 0.1 7.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF965 PF06135.7 CCD25790.2 - 0.046 13.7 0.0 0.081 12.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF965) PUL PF08324.6 CCD25791.2 - 2.5e-59 200.2 2.1 3.7e-59 199.6 1.5 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 CCD25791.2 - 2.5e-41 140.3 0.0 6.2e-41 139.0 0.0 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 CCD25791.2 - 8.9e-36 120.4 12.7 4.8e-07 29.4 0.0 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCD25791.2 - 0.00047 19.8 0.0 0.8 9.4 0.0 4.1 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Mito_carr PF00153.22 CCD25792.2 - 5.9e-51 170.1 2.0 2.3e-18 65.6 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF829 PF05705.9 CCD25792.2 - 0.025 14.2 0.0 0.046 13.4 0.0 1.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) Minor_tail_Z PF06763.6 CCD25792.2 - 0.11 12.0 0.0 0.44 10.1 0.0 1.8 2 0 0 2 2 2 0 Prophage minor tail protein Z (GPZ) DUF2015 PF09435.5 CCD25793.2 - 6.8e-36 122.8 1.4 7.3e-36 122.7 1.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) DUF1837 PF08878.6 CCD25793.2 - 0.042 13.4 0.7 0.053 13.1 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1837) RRM_1 PF00076.17 CCD25794.2 - 2.5e-58 193.5 0.1 1.2e-20 72.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD25794.2 - 3.7e-36 122.9 0.0 1.5e-11 44.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD25794.2 - 1.3e-17 63.3 0.0 1.8e-06 27.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2648 PF10855.3 CCD25794.2 - 4.6 6.7 5.4 5.2 6.5 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2648) Ribosomal_L27 PF01016.14 CCD25795.2 - 5.3e-31 106.2 0.1 9.2e-31 105.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Sedlin_N PF04628.8 CCD25799.2 - 2.8e-12 46.6 0.2 3.3e-12 46.4 0.1 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region FAD_binding_2 PF00890.19 CCD25801.2 - 7.2e-75 252.3 0.0 8.2e-75 252.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCD25801.2 - 3e-08 32.9 0.0 9.7e-05 21.4 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCD25801.2 - 4.1e-08 33.3 0.5 0.00048 20.0 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCD25801.2 - 3.3e-07 30.5 0.0 7.7e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCD25801.2 - 6.5e-07 29.2 0.0 2.1e-06 27.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCD25801.2 - 7e-06 25.2 1.2 0.00071 18.7 0.1 2.5 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 CCD25801.2 - 0.00067 18.2 2.7 0.28 9.5 0.1 3.0 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.1 CCD25801.2 - 0.0053 16.5 0.0 0.019 14.7 0.0 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 CCD25801.2 - 0.0056 15.6 0.0 0.073 11.9 0.1 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein GMC_oxred_N PF00732.14 CCD25801.2 - 0.01 15.0 0.7 4.9 6.2 0.0 2.7 3 0 0 3 3 3 0 GMC oxidoreductase FAD_binding_3 PF01494.14 CCD25801.2 - 0.025 13.6 0.0 0.076 12.0 0.1 1.7 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.13 CCD25801.2 - 0.037 13.6 0.0 0.082 12.5 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Mqo PF06039.10 CCD25801.2 - 0.037 12.2 0.8 0.06 11.5 0.0 1.6 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) GIDA PF01134.17 CCD25801.2 - 0.039 12.8 0.9 3.2 6.5 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 CCD25801.2 - 0.096 11.7 0.1 0.27 10.2 0.0 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase YL1_C PF08265.6 CCD25802.2 - 2.3e-15 55.8 0.4 3.5e-15 55.2 0.3 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain REV PF00424.13 CCD25802.2 - 0.063 13.1 1.3 0.091 12.6 0.9 1.3 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Lipase_GDSL_3 PF14606.1 CCD25802.2 - 0.077 12.7 0.4 0.1 12.3 0.3 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RseA_C PF03873.8 CCD25802.2 - 0.18 11.7 2.0 0.4 10.5 1.4 1.7 1 1 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain GDA1_CD39 PF01150.12 CCD25804.2 - 5.6e-118 394.1 0.0 7e-118 393.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 CCD25804.2 - 0.064 12.4 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family RNA_pol_Rpb1_4 PF05000.12 CCD25804.2 - 0.087 12.5 0.1 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 SR-25 PF10500.4 CCD25804.2 - 6.2 6.2 13.4 8.6 5.7 9.3 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NAD_kinase PF01513.16 CCD25805.2 - 2.1e-74 249.8 0.0 3.2e-74 249.2 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Glyco_hydro_16 PF00722.16 CCD25806.2 - 6e-42 143.0 4.4 6e-42 143.0 3.1 2.0 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Baculo_VP91_N PF08475.5 CCD25806.2 - 0.0073 15.6 0.0 0.015 14.6 0.0 1.4 1 0 0 1 1 1 1 Viral capsid protein 91 N-terminal Chitin_bind_1 PF00187.14 CCD25806.2 - 0.48 10.4 12.8 0.94 9.5 8.8 1.4 1 0 0 1 1 1 0 Chitin recognition protein DUF1675 PF07897.6 CCD25806.2 - 6.2 6.6 18.5 11 5.7 12.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) PAP1 PF08601.5 CCD25806.2 - 8.2 5.9 27.8 13 5.3 19.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 DUF572 PF04502.8 CCD25806.2 - 9.2 5.3 17.6 14 4.8 12.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Cytochrom_C PF00034.16 CCD25807.2 - 2.1e-10 41.2 0.0 3.2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CCD25807.2 - 7.8e-08 32.3 1.3 9.7e-07 28.8 0.9 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CCD25807.2 - 0.0048 16.3 0.2 0.018 14.5 0.1 1.8 2 0 0 2 2 2 1 Cytochrome c-550 domain HAD_2 PF13419.1 CCD25808.2 - 1.3e-16 61.3 0.0 1.8e-16 60.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UBA PF00627.26 CCD25809.2 - 7.6e-24 82.8 3.5 3.7e-14 52.0 0.2 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 CCD25809.2 - 7.9e-16 57.2 2.0 2.2e-15 55.8 1.1 1.9 2 0 0 2 2 2 1 Ubiquitin family XPC-binding PF09280.6 CCD25809.2 - 1.3e-12 46.9 0.4 1.3e-12 46.9 0.2 1.9 2 0 0 2 2 2 1 XPC-binding domain Rad60-SLD PF11976.3 CCD25809.2 - 2.6e-08 33.4 1.0 6.8e-08 32.0 0.7 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CCD25809.2 - 3.2e-05 23.7 0.1 9.7e-05 22.2 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCD25809.2 - 0.0021 18.1 0.0 0.0045 17.1 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain CUE PF02845.11 CCD25809.2 - 0.034 13.6 0.7 4 7.0 0.0 4.2 3 2 1 4 4 4 0 CUE domain UBA_3 PF09288.5 CCD25809.2 - 0.035 13.7 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF2868 PF11067.3 CCD25809.2 - 7.2 5.6 8.1 34 3.4 5.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2868) Anp1 PF03452.9 CCD25810.2 - 7.7e-124 412.1 0.0 1.9e-123 410.8 0.0 1.6 2 0 0 2 2 2 1 Anp1 GldH_lipo PF14109.1 CCD25810.2 - 0.023 14.8 0.0 0.096 12.9 0.0 2.1 1 1 0 1 1 1 0 GldH lipoprotein eIF-5a PF01287.15 CCD25811.2 - 5.2e-29 99.9 0.7 7.6e-29 99.4 0.5 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CCD25811.2 - 0.00025 20.6 0.5 0.00053 19.6 0.4 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 CCD25811.2 - 0.036 13.9 0.0 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain TcdB_toxin_midN PF12256.3 CCD25811.2 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region DUF3589 PF12141.3 CCD25812.2 - 2.8e-103 345.8 3.0 2e-102 342.9 2.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) SR-25 PF10500.4 CCD25812.2 - 1.1 8.6 17.1 2.4 7.5 11.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MCM PF00493.18 CCD25813.2 - 3.9e-128 426.8 0.1 7e-128 426.0 0.1 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCD25813.2 - 7.2e-25 87.8 0.1 3e-24 85.8 0.0 2.2 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCD25813.2 - 1.4e-07 30.8 0.0 1.6e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCD25813.2 - 0.0042 16.6 0.0 0.0082 15.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCD25813.2 - 0.015 14.7 0.1 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Hydrolase PF00702.21 CCD25814.2 - 1.6e-23 84.2 0.0 4.9e-23 82.6 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCD25814.2 - 1.1e-21 77.8 0.1 2.3e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CCD25814.2 - 1.2e-20 73.5 0.0 2.2e-20 72.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CCD25814.2 - 9.3e-08 31.9 0.0 2.2e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCD25814.2 - 0.00018 21.1 1.3 0.0015 18.2 0.1 2.8 2 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 CCD25814.2 - 0.039 13.2 0.1 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase PfkB PF00294.19 CCD25815.2 - 1.6e-09 37.3 0.0 4e-08 32.7 0.0 2.2 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CCD25815.2 - 3.5e-07 29.6 0.0 4.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Tubulin-binding PF00418.14 CCD25815.2 - 0.05 13.3 0.1 0.095 12.4 0.1 1.4 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat RVT_2 PF07727.9 CCD25816.2 - 1.3e-39 135.6 0.1 3.6e-39 134.2 0.0 1.8 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCD25816.2 - 7.6e-15 55.0 0.0 1.7e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCD25816.2 - 7.9e-06 25.4 0.0 3.1e-05 23.5 0.0 2.1 1 0 0 1 1 1 1 GAG-pre-integrase domain ATP-synt_C PF00137.16 CCD25817.2 - 3.4e-33 113.3 28.3 1.2e-18 66.7 6.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Nucleopor_Nup85 PF07575.8 CCD25818.2 - 3.9e-149 497.4 18.5 1.3e-148 495.7 12.8 1.7 1 1 0 1 1 1 1 Nup85 Nucleoporin UCR_TM PF02921.9 CCD25819.2 - 3e-20 72.2 0.9 5e-20 71.4 0.6 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 CCD25819.2 - 3.3e-18 65.0 0.0 5.4e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF641 PF04859.7 CCD25820.2 - 0.011 15.5 4.4 0.011 15.5 3.0 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Pax7 PF12360.3 CCD25820.2 - 0.11 12.7 4.3 0.18 12.1 0.5 2.3 2 0 0 2 2 2 0 Paired box protein 7 Ly49 PF08391.5 CCD25820.2 - 0.61 10.2 14.1 0.12 12.5 3.5 2.8 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF1635 PF07795.6 CCD25820.2 - 0.64 9.3 7.8 0.26 10.6 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) V_ATPase_I PF01496.14 CCD25820.2 - 3.7 5.2 12.2 0.12 10.1 2.2 2.5 3 0 0 3 3 3 0 V-type ATPase 116kDa subunit family DUF2235 PF09994.4 CCD25821.2 - 3.6e-78 262.7 0.0 8e-78 261.6 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Sec7 PF01369.15 CCD25822.2 - 4.6e-61 205.8 0.2 9.9e-61 204.7 0.2 1.6 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CCD25822.2 - 9.7e-11 41.3 3.1 9.7e-11 41.3 2.2 2.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal OMPdecase PF00215.19 CCD25823.2 - 3.7e-74 248.9 0.0 4.3e-74 248.7 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family zf-Tim10_DDP PF02953.10 CCD25824.2 - 1.2e-20 72.5 6.7 1.5e-20 72.1 4.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ku_PK_bind PF08785.6 CCD25824.2 - 0.021 14.7 2.3 0.023 14.5 1.6 1.1 1 0 0 1 1 1 0 Ku C terminal domain like Mmp37 PF09139.6 CCD25824.2 - 0.049 12.6 0.3 0.051 12.5 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 DUF1178 PF06676.6 CCD25824.2 - 0.067 13.3 0.3 0.1 12.8 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) Phasin_2 PF09361.5 CCD25824.2 - 0.075 13.0 0.1 0.25 11.3 0.1 1.8 1 1 1 2 2 2 0 Phasin protein Pepsin-I3 PF06394.8 CCD25824.2 - 0.08 12.6 0.6 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Vicilin_N PF04702.7 CCD25824.2 - 0.6 9.7 5.3 0.79 9.3 3.7 1.2 1 0 0 1 1 1 0 Vicilin N terminal region MFS_1 PF07690.11 CCD25825.2 - 3.4e-23 81.9 14.8 3.4e-23 81.9 10.2 2.7 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 CCD25825.2 - 1.4e-05 23.7 13.4 7.2e-05 21.3 1.0 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein COG6 PF06419.6 CCD25826.2 - 9.7e-133 443.4 49.5 1.9e-130 435.9 34.3 2.2 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 YhdB PF14148.1 CCD25826.2 - 0.035 13.8 1.0 0.53 10.0 0.2 2.9 2 0 0 2 2 2 0 YhdB-like protein DUF2722 PF10846.3 CCD25827.2 - 3.3e-30 105.4 58.1 8.2e-30 104.1 40.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) TPP_enzyme_N PF02776.13 CCD25828.2 - 1.1e-35 122.5 0.0 2.6e-35 121.4 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCD25828.2 - 8.1e-21 74.2 0.0 1.4e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCD25828.2 - 1.2e-18 67.1 0.1 7.2e-18 64.6 0.0 2.2 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain zf-Nse PF11789.3 CCD25829.2 - 7.7e-20 70.1 1.0 1.1e-19 69.6 0.1 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 CCD25829.2 - 0.0012 18.6 0.7 0.0028 17.4 0.3 1.8 2 0 0 2 2 2 1 Ring finger domain Rtf2 PF04641.7 CCD25829.2 - 0.0014 17.8 2.7 0.0075 15.4 0.1 2.1 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 CCD25829.2 - 0.0057 16.2 0.3 0.014 15.0 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCD25829.2 - 0.02 14.5 0.7 0.051 13.2 0.5 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 CCD25829.2 - 0.029 13.8 0.3 0.096 12.2 0.2 1.9 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 CCD25829.2 - 0.086 12.6 0.5 0.2 11.4 0.3 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 CCD25829.2 - 0.26 11.3 1.9 0.65 10.0 1.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) rve PF00665.21 CCD25831.2 - 6.6e-19 68.1 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCD25831.2 - 0.015 14.8 0.2 0.034 13.7 0.1 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain Pro_CA PF00484.14 CCD25833.2 - 1.5e-31 109.4 0.0 2e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Glyco_hydro_15 PF00723.16 CCD25834.2 - 3.5e-49 167.5 0.0 6.5e-49 166.6 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 15 PIG-H PF10181.4 CCD25835.2 - 4.9e-19 67.7 1.2 8e-19 67.0 0.2 1.8 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component rve PF00665.21 CCD25836.2 - 2.6e-19 69.4 0.1 7.3e-19 68.0 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.1 CCD25836.2 - 4.4e-05 23.0 0.1 0.00012 21.6 0.1 1.8 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.1 CCD25836.2 - 0.09 12.3 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Vps35 PF03635.12 CCD25837.2 - 2.6e-09 35.8 0.0 3.6e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Myb_DNA-binding PF00249.26 CCD25838.2 - 1.9e-09 37.4 0.0 7.1e-09 35.5 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCD25838.2 - 0.018 15.1 0.1 0.11 12.6 0.1 2.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain WD40 PF00400.27 CCD25839.2 - 6.4e-09 35.3 2.1 6e-05 22.7 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat CwfJ_C_2 PF04676.9 CCD25839.2 - 0.045 14.2 0.6 0.087 13.3 0.4 1.5 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 Colipase PF01114.13 CCD25839.2 - 0.24 10.9 1.0 0.43 10.1 0.7 1.4 1 0 0 1 1 1 0 Colipase, N-terminal domain Pkinase PF00069.20 CCD25840.2 - 2.7e-38 131.6 0.0 5.6e-38 130.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25840.2 - 4.9e-30 104.4 0.0 9e-30 103.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD25840.2 - 0.00041 19.3 0.0 0.00089 18.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCD25840.2 - 0.032 13.9 0.0 0.14 11.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Hist_deacetyl PF00850.14 CCD25841.2 - 2.3e-94 316.2 0.0 2.9e-94 315.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 CCD25841.2 - 7.1e-52 175.4 2.7 1.1e-51 174.8 1.9 1.3 1 0 0 1 1 1 1 Arb2 domain Nol1_Nop2_Fmu PF01189.12 CCD25842.2 - 1.1e-17 64.2 0.1 6.7e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CCD25842.2 - 0.0036 17.3 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CCD25842.2 - 0.0056 15.7 0.0 0.014 14.4 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_15 PF09445.5 CCD25842.2 - 0.013 15.0 0.1 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase R3H PF01424.17 CCD25843.2 - 5e-13 48.5 0.0 9.5e-13 47.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 CCD25843.2 - 3.2e-10 39.7 164.2 1.7e-05 24.6 11.2 11.9 10 3 0 10 10 10 6 NF-X1 type zinc finger Methyltransf_16 PF10294.4 CCD25844.2 - 3e-51 173.3 1.8 1.2e-49 168.1 1.2 2.0 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 CCD25844.2 - 0.06 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_18 PF12847.2 CCD25844.2 - 0.089 13.3 0.0 0.19 12.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain DUF1242 PF06842.7 CCD25845.2 - 2e-19 68.8 0.3 2.6e-19 68.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF2366 PF10171.4 CCD25845.2 - 0.05 13.0 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2366) SPAM PF02090.10 CCD25845.2 - 0.06 13.3 0.0 0.061 13.3 0.0 1.1 1 0 0 1 1 1 0 Salmonella surface presentation of antigen gene type M protein Cyclin_N PF00134.18 CCD25846.2 - 4.4e-16 58.6 0.6 1.3e-15 57.1 0.3 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCD25846.2 - 0.001 18.9 3.4 0.41 10.5 0.0 3.7 3 0 0 3 3 3 2 Cyclin, C-terminal domain RNA_pol_3_Rpc31 PF11705.3 CCD25846.2 - 0.04 13.8 0.3 0.04 13.8 0.2 1.6 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Bac_surface_Ag PF01103.18 CCD25847.2 - 1.6e-34 119.8 14.7 1.6e-34 119.8 10.2 1.4 2 0 0 2 2 2 1 Surface antigen zf-C2H2 PF00096.21 CCD25848.2 - 3.7e-13 48.9 12.3 7e-07 29.2 1.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCD25848.2 - 4.8e-12 45.5 11.2 3.7e-08 33.2 0.7 4.3 4 1 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCD25848.2 - 6.5e-12 44.9 10.3 3e-05 24.0 1.0 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-met PF12874.2 CCD25848.2 - 3.6e-09 36.5 4.9 5.1e-06 26.4 0.4 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCD25848.2 - 6e-08 32.6 8.6 0.00021 21.3 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding Zn_ribbon_recom PF13408.1 CCD25848.2 - 0.004 17.3 3.2 0.004 17.3 2.2 2.9 3 0 0 3 3 3 1 Recombinase zinc beta ribbon domain zf-C2H2_6 PF13912.1 CCD25848.2 - 0.015 15.1 5.6 7.1 6.6 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met2 PF12907.2 CCD25848.2 - 0.04 13.9 1.3 5.5 7.0 0.1 2.5 2 0 0 2 2 2 0 Zinc-binding zf-BED PF02892.10 CCD25848.2 - 0.42 10.4 10.1 0.84 9.4 1.0 3.5 2 1 1 3 3 3 0 BED zinc finger C1_4 PF07975.7 CCD25848.2 - 2.8 8.0 4.6 9.7 6.2 2.4 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain Met_10 PF02475.11 CCD25849.2 - 6.4e-10 38.9 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 CCD25849.2 - 2.5e-05 23.9 0.0 5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCD25849.2 - 0.0079 16.2 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD25849.2 - 0.033 14.7 0.0 0.06 13.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 CCD25849.2 - 0.034 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 CCD25849.2 - 0.041 13.0 0.0 0.065 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.1 CCD25849.2 - 0.14 11.8 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_transf_15 PF01793.11 CCD25850.2 - 1.8e-116 388.7 27.1 9.1e-116 386.4 18.8 1.8 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase SPT2 PF08243.6 CCD25850.2 - 0.93 9.8 5.4 3 8.1 2.6 2.5 1 1 1 2 2 2 0 SPT2 chromatin protein Histone PF00125.19 CCD25851.2 - 2.3e-15 56.4 0.3 2.8e-15 56.2 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCD25851.2 - 1.6e-05 24.8 0.1 2.8e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CCD25851.2 - 3.7e-05 23.5 0.2 5.2e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CCD25851.2 - 4.8e-05 23.4 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CCD25851.2 - 0.0013 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CCD25851.2 - 0.0058 16.3 0.1 0.0072 16.0 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 CCD25851.2 - 0.04 14.1 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 CCD25851.2 - 0.13 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 CCD25852.2 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCD25852.2 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCD25852.2 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCD25852.2 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Y_phosphatase2 PF03162.8 CCD25853.2 - 3e-66 221.8 0.1 5.2e-66 221.0 0.1 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCD25853.2 - 2.9e-07 30.8 0.0 5.9e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 CCD25853.2 - 0.0017 17.9 0.0 0.0036 16.8 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCD25853.2 - 0.006 15.9 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase UCH PF00443.24 CCD25854.2 - 3.2e-41 141.2 14.2 5.1e-41 140.5 9.9 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Frataxin_Cyay PF01491.11 CCD25855.2 - 5.8e-29 100.0 0.0 7.8e-29 99.6 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain RE_SinI PF09570.5 CCD25855.2 - 0.014 14.3 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 SinI restriction endonuclease Inhibitor_I9 PF05922.11 CCD25856.2 - 0.00064 20.2 0.1 0.00091 19.7 0.1 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I9 ABC_tran PF00005.22 CCD25857.2 - 5.1e-46 156.3 0.0 8.2e-22 77.9 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCD25857.2 - 2e-18 67.3 5.2 2.3e-05 24.5 0.0 4.8 4 1 1 5 5 4 4 AAA domain SMC_N PF02463.14 CCD25857.2 - 1.6e-14 53.6 0.3 5.9e-06 25.6 0.0 4.3 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCD25857.2 - 9.4e-10 37.8 0.1 0.0014 18.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CCD25857.2 - 4e-09 36.7 0.1 0.00024 21.2 0.0 4.2 5 1 0 5 5 4 2 AAA domain AAA_28 PF13521.1 CCD25857.2 - 5.1e-08 33.0 0.0 0.0018 18.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCD25857.2 - 6.3e-08 31.9 0.1 0.00039 19.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 CCD25857.2 - 8.7e-08 32.7 6.0 0.0022 18.3 0.0 3.4 4 0 0 4 4 2 2 AAA domain MMR_HSR1 PF01926.18 CCD25857.2 - 3.2e-07 30.3 0.1 0.0055 16.6 0.0 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_17 PF13207.1 CCD25857.2 - 3.6e-07 31.0 0.0 0.011 16.5 0.0 3.1 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CCD25857.2 - 8.8e-07 29.4 0.0 0.081 13.4 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein SbcCD_C PF13558.1 CCD25857.2 - 1.4e-06 28.1 0.0 0.019 14.8 0.0 3.1 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Dynamin_N PF00350.18 CCD25857.2 - 1.8e-06 27.8 0.0 9.3e-05 22.3 0.0 2.9 3 0 0 3 3 2 1 Dynamin family RNA_helicase PF00910.17 CCD25857.2 - 4.9e-06 26.6 0.0 0.12 12.5 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 CCD25857.2 - 5.8e-06 26.2 0.0 0.14 12.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CCD25857.2 - 7.3e-06 25.6 0.2 0.22 10.9 0.0 3.6 4 1 0 4 4 4 2 AAA-like domain AAA_18 PF13238.1 CCD25857.2 - 1.9e-05 24.9 0.1 0.091 13.0 0.0 3.8 4 0 0 4 4 2 1 AAA domain AAA_13 PF13166.1 CCD25857.2 - 3.7e-05 22.4 0.0 2.1 6.7 0.0 3.6 3 0 0 3 3 3 1 AAA domain ArgK PF03308.11 CCD25857.2 - 3.8e-05 22.5 0.1 0.2 10.3 0.0 2.4 2 0 0 2 2 2 2 ArgK protein AAA PF00004.24 CCD25857.2 - 6.9e-05 23.0 0.1 1.6 8.9 0.0 4.1 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CCD25857.2 - 0.00011 22.0 0.1 1.4 8.8 0.0 3.9 4 0 0 4 4 4 2 AAA domain MobB PF03205.9 CCD25857.2 - 0.00013 21.6 0.0 0.43 10.2 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CCD25857.2 - 0.0002 21.3 0.4 0.16 11.9 0.0 3.6 4 0 0 4 4 3 1 AAA ATPase domain MutS_V PF00488.16 CCD25857.2 - 0.00022 20.7 0.2 0.22 10.9 0.0 2.8 3 0 0 3 3 3 1 MutS domain V NACHT PF05729.7 CCD25857.2 - 0.00027 20.6 0.0 0.23 11.0 0.0 2.8 3 0 0 3 3 2 1 NACHT domain DUF87 PF01935.12 CCD25857.2 - 0.00027 20.8 1.5 0.36 10.6 0.0 4.6 4 0 0 4 4 4 1 Domain of unknown function DUF87 HEAT_2 PF13646.1 CCD25857.2 - 0.00029 21.0 0.0 0.039 14.2 0.0 3.4 1 1 3 4 4 4 1 HEAT repeats Arch_ATPase PF01637.13 CCD25857.2 - 0.00072 19.3 0.3 0.78 9.3 0.0 3.4 4 0 0 4 4 3 1 Archaeal ATPase PduV-EutP PF10662.4 CCD25857.2 - 0.00074 19.0 0.0 0.21 11.0 0.0 3.0 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation CLASP_N PF12348.3 CCD25857.2 - 0.00097 18.5 2.3 0.0045 16.3 0.9 2.3 1 1 1 2 2 2 1 CLASP N terminal ParcG PF10274.4 CCD25857.2 - 0.0021 17.9 0.5 5.4 6.8 0.0 3.1 1 1 2 3 3 3 0 Parkin co-regulated protein Septin PF00735.13 CCD25857.2 - 0.0022 17.0 1.1 1.5 7.7 0.0 3.4 3 0 0 3 3 3 1 Septin Cnd1 PF12717.2 CCD25857.2 - 0.0022 17.8 2.4 0.068 13.0 0.1 2.8 2 1 1 3 3 2 1 non-SMC mitotic condensation complex subunit 1 AAA_30 PF13604.1 CCD25857.2 - 0.0035 16.9 0.2 4.6 6.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 CCD25857.2 - 0.0036 16.7 3.5 0.81 9.1 0.0 3.9 4 1 1 5 5 4 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 CCD25857.2 - 0.0065 15.8 0.0 3.5 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain HEAT PF02985.17 CCD25857.2 - 0.013 15.5 0.1 17 5.7 0.0 3.9 4 0 0 4 4 2 0 HEAT repeat HEAT_EZ PF13513.1 CCD25857.2 - 0.013 16.0 0.5 23 5.6 0.0 4.4 3 2 2 5 5 4 0 HEAT-like repeat FtsK_SpoIIIE PF01580.13 CCD25857.2 - 0.02 14.3 0.3 1.5 8.2 0.0 2.9 3 0 0 3 3 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 CCD25857.2 - 0.025 13.7 0.0 1.7 7.7 0.0 3.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CCD25857.2 - 0.029 13.4 0.1 5.7 5.9 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.12 CCD25857.2 - 0.058 12.9 0.5 8.8 5.7 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ATP-synt_ab PF00006.20 CCD25857.2 - 0.093 12.2 0.0 14 5.1 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain UME PF08064.8 CCD25857.2 - 0.16 11.9 2.4 0.31 11.0 1.0 2.0 2 0 0 2 2 1 0 UME (NUC010) domain PLA2_B PF01735.13 CCD25858.2 - 3.1e-84 282.9 10.6 4.1e-70 236.3 3.0 2.4 2 0 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.17 CCD25858.2 - 0.00021 21.3 0.0 0.00066 19.6 0.0 1.9 2 1 0 2 2 2 1 Patatin-like phospholipase UPF0052 PF01933.13 CCD25859.2 - 6.9e-71 239.0 0.0 1.3e-70 238.1 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family UPF0052 HAD PF12710.2 CCD25860.2 - 2.3e-15 57.2 0.2 3.2e-15 56.8 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCD25860.2 - 7.6e-07 29.5 0.0 6.6e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 CCD25860.2 - 9.2e-07 28.2 0.0 1.5e-06 27.6 0.0 1.3 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.7 CCD25860.2 - 0.0002 20.7 0.0 0.00065 19.0 0.0 1.8 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF4326 PF14216.1 CCD25860.2 - 0.097 13.2 0.0 0.22 12.0 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4326) SpoU_sub_bind PF08032.7 CCD25860.2 - 0.13 12.4 0.0 0.59 10.3 0.0 2.0 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Iso_dh PF00180.15 CCD25861.2 - 3.1e-64 217.1 0.0 3.7e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase TRA-1_regulated PF02343.11 CCD25862.2 - 0.002 17.6 0.1 0.0064 15.9 0.1 1.9 1 0 0 1 1 1 1 TRA-1 regulated protein R03H10.4 QRPTase_C PF01729.14 CCD25863.2 - 7.4e-57 191.5 0.0 9.2e-57 191.2 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 CCD25863.2 - 6e-23 80.4 0.0 2.2e-22 78.6 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribosomal_L2_C PF03947.13 CCD25864.2 - 0.059 13.1 0.2 0.068 12.9 0.2 1.1 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain Proteasome PF00227.21 CCD25865.2 - 6.3e-58 195.1 0.3 7.9e-58 194.8 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCD25865.2 - 2.1e-13 49.3 0.2 4.1e-13 48.3 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature UQ_con PF00179.21 CCD25867.2 - 8.7e-35 119.1 0.5 9.9e-35 119.0 0.3 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.6 CCD25867.2 - 0.00013 21.4 0.2 0.00019 20.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.1 CCD25867.2 - 0.00015 21.4 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCD25867.2 - 0.032 14.1 0.1 0.04 13.7 0.1 1.3 1 0 0 1 1 1 0 RWD domain UEV PF05743.8 CCD25867.2 - 0.036 13.7 0.5 0.055 13.1 0.3 1.3 1 0 0 1 1 1 0 UEV domain Band_7 PF01145.20 CCD25868.2 - 9.1e-27 94.1 0.8 1.5e-26 93.4 0.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family MARVEL PF01284.18 CCD25869.2 - 1.2e-24 86.7 11.2 1.6e-24 86.3 7.8 1.1 1 0 0 1 1 1 1 Membrane-associating domain SYF2 PF08231.7 CCD25871.2 - 6.3e-09 36.1 21.9 6.3e-09 36.1 15.2 2.0 2 0 0 2 2 2 1 SYF2 splicing factor FYVE_2 PF02318.11 CCD25871.2 - 0.026 14.3 1.5 0.064 13.1 1.0 1.8 1 0 0 1 1 1 0 FYVE-type zinc finger DUF763 PF05559.6 CCD25871.2 - 7.9 5.3 11.0 0.46 9.3 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF763) Utp8 PF10395.4 CCD25872.2 - 9.8e-201 668.5 39.3 1.1e-200 668.3 27.3 1.0 1 0 0 1 1 1 1 Utp8 family NRDE PF05742.7 CCD25873.2 - 6.3e-53 179.8 0.3 1.6e-39 135.8 0.1 2.0 2 0 0 2 2 2 2 NRDE protein DUF3484 PF11983.3 CCD25874.2 - 3 8.7 8.7 0.41 11.5 1.0 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF3484) PLRV_ORF5 PF01690.12 CCD25874.2 - 3.8 6.5 14.5 4.6 6.2 10.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Sulfate_transp PF00916.15 CCD25875.2 - 9.6e-54 182.2 14.6 2.1e-53 181.1 10.1 1.6 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 CCD25875.2 - 3.4e-15 55.5 0.9 1e-14 53.9 0.6 1.9 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 CCD25875.2 - 0.0016 18.1 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain COG2 PF06148.6 CCD25877.2 - 7.2e-10 38.8 4.6 1.7e-09 37.6 3.2 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF1993 PF09351.5 CCD25877.2 - 0.14 12.0 0.4 16 5.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1993) Syntaxin_2 PF14523.1 CCD25877.2 - 0.27 11.2 4.4 0.76 9.8 0.2 2.8 1 1 1 2 2 2 0 Syntaxin-like protein Nup54 PF13874.1 CCD25878.2 - 1.1e-40 138.5 5.8 1.1e-40 138.5 4.0 2.5 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 CCD25878.2 - 2.5e-33 114.6 152.3 2.7e-16 59.8 31.4 4.8 1 1 2 4 4 4 3 Nucleoporin FG repeat region Ribosom_S12_S23 PF00164.20 CCD25879.2 - 1.7e-40 137.2 0.6 2e-40 137.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 LisH PF08513.6 CCD25880.2 - 0.00024 20.7 0.1 0.00065 19.3 0.0 1.8 1 0 0 1 1 1 1 LisH WD40 PF00400.27 CCD25880.2 - 0.061 13.2 5.1 46 4.1 0.0 4.8 4 0 0 4 4 4 0 WD domain, G-beta repeat LSM14 PF12701.2 CCD25881.2 - 2.3e-23 81.8 0.0 2.3e-23 81.8 0.0 2.6 2 1 0 2 2 2 1 Scd6-like Sm domain FDF PF09532.5 CCD25881.2 - 1e-16 61.3 6.4 1e-16 61.3 4.4 3.0 2 1 0 2 2 2 1 FDF domain SM-ATX PF14438.1 CCD25881.2 - 0.01 15.7 0.0 0.03 14.2 0.0 1.9 1 0 0 1 1 1 0 Ataxin 2 SM domain Zip PF02535.17 CCD25881.2 - 2.7 6.9 11.4 4.6 6.1 7.9 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter DASH_Dam1 PF08653.5 CCD25882.2 - 3.7e-28 97.0 1.4 1.2e-27 95.4 0.1 2.2 2 0 0 2 2 2 1 DASH complex subunit Dam1 Hrs_helical PF12210.3 CCD25882.2 - 0.019 15.2 0.9 0.18 12.0 0.1 2.7 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF1192 PF06698.6 CCD25882.2 - 0.073 12.8 3.6 0.22 11.3 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) SURF1 PF02104.10 CCD25883.2 - 3.7e-66 222.9 0.0 7.1e-66 222.0 0.0 1.4 1 1 0 1 1 1 1 SURF1 family ig PF00047.20 CCD25883.2 - 0.18 11.9 0.3 0.45 10.6 0.0 1.8 2 0 0 2 2 2 0 Immunoglobulin domain Acetyltransf_7 PF13508.1 CCD25884.2 - 0.0015 18.6 0.0 0.0044 17.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCD25884.2 - 0.054 13.5 0.1 0.23 11.5 0.0 2.1 3 0 0 3 3 3 0 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CCD25884.2 - 0.15 11.8 0.0 1.3 8.8 0.0 2.4 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain Abhydrolase_1 PF00561.15 CCD25885.2 - 1.8e-21 76.7 0.2 1.8e-21 76.7 0.1 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCD25885.2 - 5.4e-20 72.2 0.0 7.5e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CCD25885.2 - 4e-06 26.5 0.0 8.9e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.2 CCD25885.2 - 1e-05 25.2 0.0 4.8e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 CCD25885.2 - 0.011 14.2 0.0 0.023 13.1 0.0 1.5 1 1 0 1 1 1 0 Ndr family DUF2305 PF10230.4 CCD25885.2 - 0.015 14.7 0.1 0.034 13.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF2034 PF10356.4 CCD25885.2 - 0.066 12.3 0.9 1.8 7.7 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2034) Cyclin_N PF00134.18 CCD25886.2 - 2.5e-39 133.7 2.4 2.8e-39 133.5 0.4 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCD25886.2 - 1.4e-18 66.9 0.3 4.7e-18 65.2 0.1 2.0 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 CCD25887.2 - 4.4e-43 145.8 2.8 1.5e-40 137.6 0.2 3.2 3 0 0 3 3 3 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCD25887.2 - 4.4e-29 100.8 0.1 1.2e-28 99.3 0.0 1.8 2 0 0 2 2 2 1 Cyclin, C-terminal domain PA14 PF07691.7 CCD25888.2 - 2.3e-28 98.6 0.3 2.9e-14 52.9 0.0 3.0 2 1 1 3 3 3 2 PA14 domain PA14_2 PF10528.4 CCD25888.2 - 9.3e-25 86.7 6.4 1.1e-13 51.0 0.2 3.2 2 0 0 2 2 2 2 GLEYA domain ATP-synt_S1 PF05827.7 CCD25889.2 - 2.4e-05 23.8 1.7 0.00057 19.2 0.0 2.8 2 1 1 3 3 3 2 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF912 PF06024.7 CCD25889.2 - 0.1 12.6 1.0 0.18 11.8 0.1 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) VMA21 PF09446.5 CCD25890.2 - 4.1e-14 52.2 6.9 5.5e-14 51.8 4.8 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF1430 PF07242.6 CCD25890.2 - 0.11 12.6 1.1 0.12 12.4 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) PrgI PF12666.2 CCD25890.2 - 0.23 11.6 1.6 0.3 11.2 1.1 1.2 1 0 0 1 1 1 0 PrgI family protein Med18 PF09637.5 CCD25891.2 - 7.4e-65 218.9 1.9 8.4e-65 218.7 1.3 1.0 1 0 0 1 1 1 1 Med18 protein Eaf7 PF07904.8 CCD25891.2 - 0.047 13.6 0.0 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 Pescadillo_N PF06732.6 CCD25892.2 - 4.8e-85 285.2 0.4 4.8e-85 285.2 0.3 2.9 3 0 0 3 3 3 1 Pescadillo N-terminus BRCT PF00533.21 CCD25892.2 - 9.1e-11 41.7 0.1 4e-10 39.7 0.0 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Rhomboid PF01694.17 CCD25894.2 - 3.4e-29 101.7 17.5 3.4e-29 101.7 12.1 1.6 2 0 0 2 2 2 1 Rhomboid family RabGAP-TBC PF00566.13 CCD25895.2 - 6.2e-49 166.3 0.4 1.9e-48 164.7 0.2 1.9 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GRAM PF02893.15 CCD25895.2 - 8.4e-12 44.4 0.0 2.8e-11 42.7 0.0 2.0 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.1 CCD25895.2 - 1.4e-05 25.1 0.7 5e-05 23.3 0.3 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CCD25895.2 - 2.2e-05 23.9 0.6 0.012 15.4 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain Vps36_ESCRT-II PF11605.3 CCD25895.2 - 0.031 14.0 0.1 0.13 12.0 0.1 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 EF-hand_1 PF00036.27 CCD25895.2 - 0.06 12.6 0.8 0.3 10.5 0.1 2.5 2 0 0 2 2 2 0 EF hand Telomere_reg-2 PF10193.4 CCD25896.2 - 2.6e-26 92.1 2.3 3.8e-26 91.5 0.6 2.0 2 0 0 2 2 2 1 Telomere length regulation protein Peptidase_C50 PF03568.12 CCD25897.2 - 4.5e-126 420.5 1.6 4.5e-126 420.5 1.1 3.4 3 1 1 4 4 4 1 Peptidase family C50 CHAT PF12770.2 CCD25897.2 - 0.013 14.5 0.0 0.17 11.0 0.0 2.4 2 1 0 2 2 2 0 CHAT domain Flavin_Reduct PF01613.13 CCD25898.2 - 4.3e-31 107.8 0.0 7.1e-31 107.1 0.0 1.3 1 1 0 1 1 1 1 Flavin reductase like domain PH PF00169.24 CCD25899.2 - 7.3e-15 55.0 8.0 8.2e-14 51.6 5.5 2.9 1 1 0 1 1 1 1 PH domain Mito_carr PF00153.22 CCD25900.2 - 1.7e-58 194.3 0.7 7.4e-20 70.4 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein RNase_PH PF01138.16 CCD25901.2 - 1.6e-17 64.0 0.0 1.6e-17 64.0 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCD25901.2 - 6.1e-06 26.0 0.7 1.6e-05 24.7 0.2 1.9 1 1 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF2987 PF11205.3 CCD25901.2 - 0.16 11.5 0.7 12 5.4 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2987) tRNA-synt_1 PF00133.17 CCD25902.2 - 1.4e-215 716.8 0.9 7.5e-215 714.4 0.6 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCD25902.2 - 4.3e-26 91.4 1.7 1.2e-25 90.0 1.2 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCD25902.2 - 2.8e-16 59.1 6.7 5.2e-08 31.9 0.0 5.0 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CCD25902.2 - 4.3e-10 39.2 0.0 6.8e-07 28.7 0.0 2.7 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 CCD25902.2 - 2.2e-06 27.6 5.4 5.8e-06 26.2 3.7 1.8 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1d PF00750.14 CCD25902.2 - 0.00063 18.6 1.4 0.043 12.6 0.0 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (R) Peptidase_S24 PF00717.18 CCD25902.2 - 0.07 12.7 0.2 0.75 9.4 0.0 2.8 3 0 0 3 3 3 0 Peptidase S24-like CwfJ_C_1 PF04677.10 CCD25903.2 - 2e-31 108.1 3.9 2.7e-31 107.7 0.5 2.6 2 1 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CCD25903.2 - 3.9e-23 81.7 2.0 3.9e-23 81.7 1.4 1.9 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.20 CCD25904.2 - 6.8e-53 179.4 0.1 9.5e-52 175.7 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25904.2 - 7.1e-28 97.3 0.3 6.6e-20 71.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 CCD25904.2 - 0.00011 22.6 0.7 0.00027 21.4 0.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCD25904.2 - 0.00038 19.4 0.0 0.015 14.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCD25904.2 - 0.024 13.6 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD25904.2 - 0.072 12.8 0.1 0.31 10.7 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family Nop PF01798.13 CCD25905.2 - 5.8e-44 149.0 0.1 1e-43 148.2 0.1 1.4 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 CCD25905.2 - 6.3e-30 104.1 5.1 1.7e-29 102.7 3.5 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 CCD25905.2 - 8.1e-08 31.9 0.6 2.4e-07 30.4 0.4 1.8 1 0 0 1 1 1 1 NOSIC (NUC001) domain Chalcone PF02431.10 CCD25905.2 - 0.02 14.3 0.2 0.057 12.8 0.2 1.8 1 0 0 1 1 1 0 Chalcone-flavanone isomerase SASRP1 PF15160.1 CCD25905.2 - 0.023 13.9 0.7 0.32 10.1 0.2 2.2 2 0 0 2 2 2 0 Spermatogenesis-associated serine-rich protein 1 Nrap PF03813.9 CCD25906.2 - 0 1198.8 6.0 0 1198.6 4.2 1.0 1 0 0 1 1 1 1 Nrap protein PBP1_TM PF14812.1 CCD25906.2 - 0.43 10.9 2.1 0.82 10.0 1.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.9 CCD25906.2 - 2.1 7.8 8.1 3.7 7.0 5.6 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Catalase PF00199.14 CCD25908.2 - 9.2e-148 492.0 0.6 3.6e-147 490.0 0.4 1.9 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CCD25908.2 - 3.6e-13 49.1 0.0 1e-12 47.7 0.0 1.7 2 0 0 2 2 2 1 Catalase-related immune-responsive DUF2111 PF09884.4 CCD25908.2 - 0.036 13.9 0.0 0.092 12.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2111) Pil1 PF13805.1 CCD25909.2 - 9e-152 503.8 0.6 1.1e-151 503.4 0.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 zf-DHHC PF01529.15 CCD25910.2 - 6.6e-38 129.8 17.9 6.6e-38 129.8 12.4 1.7 1 1 0 2 2 2 1 DHHC palmitoyltransferase DUF402 PF04167.8 CCD25910.2 - 0.022 14.6 0.0 0.076 12.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF402) BPD_transp_1 PF00528.17 CCD25910.2 - 2 7.8 10.9 2.9 7.3 3.2 2.3 2 0 0 2 2 2 0 Binding-protein-dependent transport system inner membrane component FtsX PF02687.16 CCD25910.2 - 9.4 6.0 13.2 0.74 9.5 4.5 2.4 2 1 1 3 3 3 0 FtsX-like permease family Porph_ging PF09697.5 CCD25911.2 - 0.052 13.6 1.2 6.6 6.9 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) DnaJ PF00226.26 CCD25912.2 - 4.3e-05 23.1 0.2 6.3e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CCD25912.2 - 0.00094 18.9 0.1 0.0012 18.5 0.1 1.2 1 0 0 1 1 1 1 Pam16 AAA PF00004.24 CCD25913.2 - 1.2e-53 180.8 0.0 6.7e-45 152.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCD25913.2 - 2e-05 24.7 0.0 0.011 15.8 0.0 3.7 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 CCD25913.2 - 5e-05 24.1 0.0 0.0027 18.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 CCD25913.2 - 6e-05 23.0 0.0 0.00036 20.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Vps4_C PF09336.5 CCD25913.2 - 0.00017 21.4 0.1 0.00068 19.4 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 CCD25913.2 - 0.00033 19.7 0.0 0.00081 18.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 CCD25913.2 - 0.00041 19.2 0.1 0.0014 17.6 0.0 1.9 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_14 PF13173.1 CCD25913.2 - 0.00051 19.9 0.0 0.013 15.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 CCD25913.2 - 0.00071 19.0 0.1 0.0079 15.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCD25913.2 - 0.0021 17.7 0.0 0.012 15.2 0.0 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CCD25913.2 - 0.0022 18.1 0.0 0.01 16.0 0.0 2.2 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 CCD25913.2 - 0.0035 16.7 0.0 0.0084 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 CCD25913.2 - 0.0046 16.9 0.1 0.13 12.2 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CCD25913.2 - 0.0089 16.3 0.3 0.11 12.7 0.0 3.1 4 0 0 4 4 3 1 AAA domain KaiC PF06745.8 CCD25913.2 - 0.014 14.5 0.0 0.034 13.2 0.0 1.6 1 0 0 1 1 1 0 KaiC TIP49 PF06068.8 CCD25913.2 - 0.015 14.0 0.0 0.029 13.1 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Mg_chelatase PF01078.16 CCD25913.2 - 0.018 14.2 0.1 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CCD25913.2 - 0.027 14.2 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 CCD25913.2 - 0.06 13.1 3.2 2 8.1 0.0 2.9 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_3 PF07726.6 CCD25913.2 - 0.074 12.6 0.0 0.61 9.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CCD25913.2 - 0.13 12.2 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCD25913.2 - 0.18 11.7 0.0 0.77 9.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sld5 PF05916.6 CCD25914.2 - 5.9e-13 49.0 0.0 7.4e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein DUF3508 PF12018.3 CCD25914.2 - 0.092 11.7 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3508) PEX11 PF05648.9 CCD25915.2 - 1.9e-53 180.9 6.0 2.2e-53 180.8 4.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) dsrm PF00035.20 CCD25916.2 - 2.9e-08 34.1 0.0 0.014 15.9 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif Nop14 PF04147.7 CCD25916.2 - 0.0031 15.5 24.8 0.0051 14.8 17.2 1.3 1 0 0 1 1 1 1 Nop14-like family Ribonuclease_3 PF00636.21 CCD25916.2 - 0.03 14.7 2.3 0.13 12.6 0.0 3.1 3 0 0 3 3 3 0 Ribonuclease III domain CDC45 PF02724.9 CCD25916.2 - 0.23 9.4 23.5 0.35 8.8 16.3 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2146 PF10220.4 CCD25916.2 - 2.1 6.2 16.8 3.1 5.6 11.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Presenilin PF01080.12 CCD25916.2 - 3.9 6.2 14.6 7.5 5.2 10.1 1.6 1 0 0 1 1 1 0 Presenilin SLX9 PF15341.1 CCD25917.2 - 5.9e-24 84.8 15.1 5.9e-24 84.8 10.5 1.7 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 MAS20 PF02064.10 CCD25918.2 - 2.5e-16 59.6 0.9 3.3e-15 56.0 0.6 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor Lip_A_acyltrans PF03279.8 CCD25918.2 - 0.009 14.9 0.2 0.22 10.3 0.0 2.0 2 0 0 2 2 2 1 Bacterial lipid A biosynthesis acyltransferase Ribosomal_S20p PF01649.13 CCD25918.2 - 0.012 15.9 1.1 0.021 15.2 0.7 1.4 1 0 0 1 1 1 0 Ribosomal protein S20 FKBP_N PF01346.13 CCD25918.2 - 0.092 12.7 5.2 0.09 12.8 2.6 1.7 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase IF-2B PF01008.12 CCD25919.2 - 1.1e-104 349.4 0.3 1.1e-104 349.4 0.2 1.9 2 0 0 2 2 2 1 Initiation factor 2 subunit family eIF3_subunit PF08597.5 CCD25919.2 - 0.28 10.6 23.6 0.0097 15.4 7.8 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit TrbI PF03743.9 CCD25919.2 - 2.2 7.7 10.7 0.35 10.3 3.4 2.4 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein Plasmodium_Vir PF05795.6 CCD25919.2 - 6.5 5.8 17.1 1.1 8.4 1.0 2.7 3 0 0 3 3 3 0 Plasmodium vivax Vir protein HNH_5 PF14279.1 CCD25920.2 - 0.02 14.9 0.0 0.074 13.0 0.0 2.0 2 0 0 2 2 2 0 HNH endonuclease Turandot PF07240.6 CCD25920.2 - 0.064 12.7 0.7 9.3 5.8 0.2 2.5 2 0 0 2 2 2 0 Stress-inducible humoral factor Turandot DUF4537 PF15057.1 CCD25921.2 - 0.077 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) DUP PF00674.13 CCD25923.2 - 2.8e-19 69.0 4.3 4.2e-19 68.4 2.7 1.5 1 1 0 1 1 1 1 DUP family Syja_N PF02383.13 CCD25924.2 - 1.6e-90 303.1 0.0 1.6e-90 303.1 0.0 3.4 4 0 0 4 4 4 1 SacI homology domain Na_Ca_ex PF01699.19 CCD25926.2 - 2.8e-25 88.5 27.8 2.1e-16 59.8 6.5 4.0 5 1 0 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 CCD25926.2 - 2.9e-14 53.2 4.5 2.9e-14 53.2 3.1 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF307) Abhydrolase_5 PF12695.2 CCD25927.2 - 2.3e-17 63.1 0.0 3.2e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCD25927.2 - 6.8e-13 49.0 0.0 1.6e-09 37.9 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD25927.2 - 2.7e-11 43.4 0.0 7.9e-08 32.1 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCD25927.2 - 6.7e-06 25.4 0.0 3.1e-05 23.3 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 CCD25927.2 - 0.00024 20.6 0.0 0.42 10.0 0.0 2.2 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 CCD25927.2 - 0.00036 20.0 0.0 0.00049 19.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.6 CCD25927.2 - 0.0011 18.7 0.0 0.011 15.4 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2305 PF10230.4 CCD25927.2 - 0.016 14.6 0.0 4.1 6.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 CCD25927.2 - 0.026 13.9 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF818 PF05677.7 CCD25927.2 - 0.026 13.2 0.1 0.046 12.4 0.0 1.3 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.3 CCD25927.2 - 0.032 14.0 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase DUF1749 PF08538.5 CCD25927.2 - 0.046 12.6 0.0 0.11 11.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1749) AXE1 PF05448.7 CCD25927.2 - 0.15 10.5 0.0 0.31 9.5 0.0 1.6 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_9 PF10081.4 CCD25927.2 - 0.19 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Sugar_tr PF00083.19 CCD25928.2 - 1e-115 386.9 30.7 1.1e-115 386.7 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD25928.2 - 1.6e-27 96.1 31.6 3.1e-24 85.3 10.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1285 PF06938.6 CCD25928.2 - 0.16 11.9 0.1 0.28 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1285) PDT PF00800.13 CCD25929.2 - 8.1e-38 129.7 0.0 1.1e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydratase ATP11 PF06644.6 CCD25930.2 - 9.4e-95 317.1 3.2 1.1e-94 316.8 2.2 1.1 1 0 0 1 1 1 1 ATP11 protein SH3BGR PF04908.10 CCD25930.2 - 0.0052 16.7 0.5 0.013 15.4 0.3 1.6 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Exonuc_X-T_C PF08411.5 CCD25930.2 - 0.018 14.0 3.8 0.027 13.5 2.7 1.3 1 0 0 1 1 1 0 Exonuclease C-terminal Prenyltransf PF01255.14 CCD25931.2 - 1.7e-78 262.8 0.0 2.1e-78 262.5 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Pyrophosphatase PF00719.14 CCD25932.2 - 3.1e-53 179.4 0.2 4.1e-53 179.0 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase PRAI PF00697.17 CCD25933.2 - 1.3e-50 171.7 0.0 1.5e-50 171.5 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Histone PF00125.19 CCD25934.2 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCD25934.2 - 9.3e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCD25934.2 - 0.0019 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCD25934.2 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CCD25935.2 - 2.3e-15 56.4 0.3 2.8e-15 56.2 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCD25935.2 - 1.6e-05 24.8 0.1 2.8e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CCD25935.2 - 3.7e-05 23.5 0.2 5.2e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CCD25935.2 - 4.8e-05 23.4 0.1 6.6e-05 23.0 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CCD25935.2 - 0.0013 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CCD25935.2 - 0.0058 16.3 0.1 0.0072 16.0 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 CCD25935.2 - 0.04 14.1 0.0 0.067 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 CCD25935.2 - 0.13 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Aldo_ket_red PF00248.16 CCD25936.2 - 3.9e-61 206.3 0.0 4.4e-61 206.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tcp11 PF05794.8 CCD25937.2 - 4.7e-67 226.6 8.7 4.7e-67 226.6 6.0 1.7 2 1 0 2 2 2 1 T-complex protein 11 Sel1 PF08238.7 CCD25938.2 - 1.2e-10 41.6 2.5 0.0026 18.3 0.0 3.4 3 0 0 3 3 3 3 Sel1 repeat TPR_11 PF13414.1 CCD25938.2 - 0.059 13.0 0.2 0.36 10.5 0.1 2.1 2 0 0 2 2 2 0 TPR repeat Aldedh PF00171.17 CCD25939.2 - 4.2e-155 516.6 0.0 4.7e-155 516.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CCD25939.2 - 0.0006 19.1 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) RCR PF12273.3 CCD25940.2 - 3.6e-18 66.3 0.2 9.1e-18 65.0 0.0 1.8 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red TMEM154 PF15102.1 CCD25940.2 - 0.00067 19.3 1.7 0.002 17.8 0.0 2.1 2 0 0 2 2 2 1 TMEM154 protein family TMEM51 PF15345.1 CCD25940.2 - 0.013 15.2 0.0 0.03 14.0 0.0 1.7 1 1 0 1 1 1 0 Transmembrane protein 51 Colicin_V PF02674.11 CCD25940.2 - 0.032 14.0 0.0 0.051 13.4 0.0 1.3 1 0 0 1 1 1 0 Colicin V production protein DUF1517 PF07466.6 CCD25940.2 - 0.046 12.7 0.1 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF2076 PF09849.4 CCD25940.2 - 0.086 12.8 0.9 14 5.6 0.0 2.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF1628 PF07790.6 CCD25940.2 - 2.1 9.1 5.1 4.3 8.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) DUF3439 PF11921.3 CCD25940.2 - 2.4 7.9 10.4 12 5.6 4.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PDGLE PF13190.1 CCD25940.2 - 3.2 7.5 8.4 2.8 7.6 3.3 2.7 3 1 1 4 4 4 0 PDGLE domain DUF1183 PF06682.7 CCD25940.2 - 8.2 5.9 7.1 2.4 7.6 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1183) Pex2_Pex12 PF04757.9 CCD25941.2 - 1.4e-14 54.1 11.8 2.6e-14 53.1 8.2 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region FdhE PF04216.7 CCD25941.2 - 0.0032 17.2 1.1 0.0046 16.7 0.8 1.2 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation DUF3594 PF12165.3 CCD25941.2 - 0.12 12.0 0.4 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3594) zf-C3HC4_2 PF13923.1 CCD25941.2 - 0.13 12.3 12.9 0.26 11.3 9.0 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CCD25941.2 - 0.26 11.1 5.2 0.59 9.9 3.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 CCD25941.2 - 0.42 10.3 9.1 0.96 9.2 6.3 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Mannosyl_trans2 PF04188.8 CCD25942.2 - 7.5e-80 269.0 33.5 2.9e-78 263.7 23.2 2.0 1 1 0 1 1 1 1 Mannosyltransferase (PIG-V)) DUF3268 PF11672.3 CCD25942.2 - 0.097 12.7 0.0 88 3.2 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3268) Ran_BP1 PF00638.13 CCD25943.2 - 1.5e-53 180.0 1.6 1.5e-53 180.0 1.1 1.8 2 0 0 2 2 2 1 RanBP1 domain WH1 PF00568.18 CCD25943.2 - 3e-05 23.7 1.1 0.0002 21.0 0.8 2.0 1 1 0 1 1 1 1 WH1 domain PCEMA1 PF07418.6 CCD25943.2 - 0.0096 15.3 1.5 0.0096 15.3 1.1 1.6 1 1 1 2 2 2 1 Acidic phosphoprotein precursor PCEMA1 Trehalase PF01204.13 CCD25944.2 - 1.3e-188 627.7 0.1 1.7e-188 627.4 0.1 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CCD25944.2 - 1.4e-17 62.7 0.7 2.3e-17 62.0 0.5 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Toxin_ToxA PF11584.3 CCD25944.2 - 0.098 12.5 0.3 0.19 11.5 0.2 1.4 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA DUF1640 PF07798.6 CCD25945.2 - 6.9e-61 205.3 8.8 8.6e-61 205.0 6.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) FTA4 PF13093.1 CCD25945.2 - 0.0036 16.7 5.4 0.0043 16.5 3.7 1.2 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1732 PF08340.6 CCD25945.2 - 0.017 14.9 6.4 0.027 14.2 4.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) FlaC_arch PF05377.6 CCD25945.2 - 0.032 14.1 2.7 2.1 8.2 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 CCD25945.2 - 0.06 11.7 10.4 0.074 11.4 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TBPIP PF07106.8 CCD25945.2 - 0.07 12.6 10.4 0.12 11.8 7.2 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spore_GerAC PF05504.6 CCD25945.2 - 0.085 12.6 5.7 0.22 11.2 3.8 1.9 1 1 1 2 2 2 0 Spore germination B3/ GerAC like, C-terminal DUF2524 PF10732.4 CCD25945.2 - 0.59 10.2 5.3 0.62 10.2 2.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2524) Phage_Mu_Gam PF07352.7 CCD25945.2 - 0.65 9.5 7.0 0.37 10.3 0.2 2.2 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Syntaxin PF00804.20 CCD25945.2 - 0.79 9.9 14.2 3.8 7.7 6.2 2.3 1 1 1 2 2 2 0 Syntaxin Baculo_PEP_C PF04513.7 CCD25945.2 - 1 9.1 4.4 8.3 6.2 2.3 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.3 CCD25945.2 - 1.7 8.6 11.9 1.1 9.2 3.3 2.3 1 1 1 2 2 2 0 YlqD protein DUF1451 PF07295.6 CCD25945.2 - 1.9 8.2 5.9 1.5 8.5 2.6 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) Atg14 PF10186.4 CCD25945.2 - 2.7 6.8 10.8 0.22 10.4 2.5 1.9 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_lysis PF03245.8 CCD25945.2 - 8.7 6.3 7.7 1.8 8.5 0.3 2.2 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein PMM PF03332.8 CCD25946.2 - 9.6e-112 371.9 0.4 1.1e-111 371.7 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CCD25946.2 - 0.00045 19.8 0.0 0.01 15.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 CCD25946.2 - 0.011 14.8 0.0 0.015 14.3 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2608 PF11019.3 CCD25946.2 - 0.11 11.5 0.1 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2608) Hydrolase PF00702.21 CCD25946.2 - 0.14 12.5 0.1 0.22 11.8 0.1 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase USP8_dimer PF08969.6 CCD25947.2 - 4.4e-07 29.8 0.1 8.2e-07 28.9 0.1 1.6 1 1 0 1 1 1 1 USP8 dimerisation domain GRAM PF02893.15 CCD25948.2 - 1.9e-15 56.1 0.3 5.3e-15 54.6 0.2 1.8 1 0 0 1 1 1 1 GRAM domain Cu-oxidase_2 PF07731.9 CCD25949.2 - 4.3e-41 139.6 9.1 1.6e-38 131.3 0.5 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CCD25949.2 - 2.9e-37 126.9 5.4 8.9e-34 115.7 1.3 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 CCD25949.2 - 3.3e-32 111.6 4.6 3.2e-27 95.3 0.0 3.4 3 0 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 CCD25949.2 - 0.0035 17.1 0.0 6.6 6.6 0.0 3.3 3 0 0 3 3 3 2 Cupredoxin-like domain SPC22 PF04573.7 CCD25950.2 - 5.3e-52 175.5 4.2 6.3e-52 175.3 2.9 1.1 1 0 0 1 1 1 1 Signal peptidase subunit Sugar_tr PF00083.19 CCD25951.2 - 2.3e-56 191.2 32.0 2.7e-56 191.0 22.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD25951.2 - 5.6e-24 84.5 33.2 3e-21 75.5 17.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 CCD25952.2 - 3.3e-56 190.3 0.2 5e-56 189.7 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD25952.2 - 1.5e-30 106.1 0.1 2.7e-29 102.0 0.1 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1395 PF07160.7 CCD25952.2 - 0.017 14.6 0.3 0.041 13.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) SH3_1 PF00018.23 CCD25953.2 - 2.4e-09 36.4 0.0 6.1e-09 35.1 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCD25953.2 - 0.00028 20.4 0.0 0.00062 19.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain HEAT_EZ PF13513.1 CCD25954.2 - 5e-19 68.1 0.0 3.4e-11 43.2 0.0 7.0 6 1 0 6 6 6 1 HEAT-like repeat HEAT PF02985.17 CCD25954.2 - 1.9e-16 58.5 5.3 0.0013 18.6 0.0 8.2 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 CCD25954.2 - 6.6e-12 45.5 0.0 2.3e-05 24.5 0.0 4.9 4 1 0 4 4 4 2 HEAT repeats CLASP_N PF12348.3 CCD25954.2 - 4.1e-05 23.0 0.2 0.018 14.3 0.0 3.6 4 0 0 4 4 4 1 CLASP N terminal IBN_N PF03810.14 CCD25954.2 - 0.0003 20.6 0.1 0.0078 16.1 0.0 3.3 2 1 0 2 2 2 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 CCD25954.2 - 0.0011 19.3 0.5 4.9 7.5 0.0 5.0 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Urb2 PF10441.4 CCD25954.2 - 0.13 11.7 1.4 2.3 7.7 0.2 3.1 3 1 1 4 4 4 0 Urb2/Npa2 family Mannosyl_trans3 PF11051.3 CCD25955.2 - 1.1e-84 284.0 1.0 1.9e-84 283.2 0.1 1.8 2 0 0 2 2 2 1 Mannosyltransferase putative Glutaredoxin PF00462.19 CCD25956.2 - 5.3e-13 48.7 0.0 1.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Glutaredoxin SpoIISA_toxin PF14171.1 CCD25956.2 - 0.0063 15.8 0.3 0.12 11.6 0.1 2.1 2 0 0 2 2 2 1 Toxin SpoIISA, type II toxin-antitoxin system GST_N_3 PF13417.1 CCD25956.2 - 0.13 12.5 0.0 0.44 10.8 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Hyphal_reg_CWP PF11765.3 CCD25957.2 - 3.3e-14 52.4 14.3 3.3e-14 52.4 9.9 1.9 2 1 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal EmrE PF13536.1 CCD25958.2 - 0.011 15.9 0.8 0.011 15.9 0.6 3.7 3 1 1 4 4 4 0 Multidrug resistance efflux transporter MerC PF03203.9 CCD25958.2 - 0.056 13.8 12.2 0.081 13.2 2.6 2.6 2 0 0 2 2 2 0 MerC mercury resistance protein SCO1-SenC PF02630.9 CCD25959.2 - 3.7e-68 228.5 0.1 5e-68 228.1 0.1 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 CCD25959.2 - 4.1e-05 23.2 0.0 0.00012 21.7 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCD25959.2 - 0.052 13.0 0.0 0.19 11.2 0.0 1.8 1 1 0 1 1 1 0 Redoxin ABC2_membrane PF01061.19 CCD25960.2 - 2.9e-67 225.9 66.5 6.8e-41 139.7 14.2 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CCD25960.2 - 9.5e-39 132.8 0.0 5.8e-18 65.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCD25960.2 - 2.9e-34 116.8 19.8 3e-33 113.5 0.0 3.5 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CCD25960.2 - 4.6e-09 36.2 0.1 9.8e-09 35.1 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 CCD25960.2 - 1.7e-08 33.9 11.3 1.7e-08 33.9 7.8 3.7 3 2 1 4 4 4 1 ABC-2 family transporter protein DUF258 PF03193.11 CCD25960.2 - 3.9e-07 29.3 0.0 0.00029 20.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCD25960.2 - 1.4e-05 25.1 0.1 0.0032 17.4 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 CCD25960.2 - 2.6e-05 23.7 0.0 0.0093 15.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 CCD25960.2 - 4e-05 23.7 1.3 0.074 13.0 0.0 4.1 5 0 0 5 5 3 1 AAA domain AAA_22 PF13401.1 CCD25960.2 - 6.8e-05 23.0 0.1 0.003 17.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CCD25960.2 - 0.00017 21.1 0.2 0.00099 18.5 0.0 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 CCD25960.2 - 0.00024 21.6 0.0 0.95 9.9 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 CCD25960.2 - 0.00031 20.2 0.1 0.016 14.7 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CCD25960.2 - 0.00082 19.3 0.1 0.17 11.8 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 CCD25960.2 - 0.0012 19.0 0.0 0.016 15.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 CCD25960.2 - 0.0026 17.0 0.0 1.1 8.3 0.0 3.2 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain UPF0079 PF02367.12 CCD25960.2 - 0.0057 16.2 0.3 0.35 10.5 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 CCD25960.2 - 0.011 15.6 0.0 0.038 13.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 CCD25960.2 - 0.011 15.4 0.7 0.25 10.9 0.1 2.4 2 0 0 2 2 2 0 NACHT domain AAA_17 PF13207.1 CCD25960.2 - 0.017 15.9 0.0 0.11 13.2 0.0 2.5 2 0 0 2 2 1 0 AAA domain AAA_10 PF12846.2 CCD25960.2 - 0.027 13.9 0.7 0.68 9.3 0.1 2.7 3 0 0 3 3 3 0 AAA-like domain FtsK_SpoIIIE PF01580.13 CCD25960.2 - 0.04 13.3 0.2 1.7 8.0 0.0 2.6 3 0 0 3 3 2 0 FtsK/SpoIIIE family Septin PF00735.13 CCD25960.2 - 0.053 12.5 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Septin AAA_28 PF13521.1 CCD25960.2 - 0.058 13.3 0.4 0.17 11.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CCD25960.2 - 0.074 12.1 0.6 12 4.9 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin Dynamin_N PF00350.18 CCD25960.2 - 0.086 12.6 0.7 0.81 9.4 0.0 2.8 3 0 0 3 3 2 0 Dynamin family AAA_24 PF13479.1 CCD25960.2 - 0.09 12.3 0.3 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CCD25960.2 - 0.11 12.0 0.2 0.55 9.7 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CCD25960.2 - 0.12 12.5 0.0 9.7 6.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CCD25960.2 - 0.13 11.8 0.1 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CCD25960.2 - 0.13 10.9 0.1 12 4.5 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_19 PF13245.1 CCD25960.2 - 0.19 11.5 0.5 7.7 6.3 0.3 2.6 2 0 0 2 2 2 0 Part of AAA domain ABC2_membrane PF01061.19 CCD25961.2 - 9.5e-71 237.2 60.7 1.4e-43 148.5 11.7 3.1 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 CCD25961.2 - 1.2e-39 134.1 1.3 8e-33 112.1 0.0 3.0 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 CCD25961.2 - 6.6e-39 133.3 0.0 6.2e-18 65.4 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_trans_N PF14510.1 CCD25961.2 - 8.2e-12 45.0 0.0 1.8e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 CCD25961.2 - 1.2e-08 34.4 39.7 3.7e-08 32.7 4.1 3.4 3 1 0 3 3 3 1 ABC-2 family transporter protein DUF258 PF03193.11 CCD25961.2 - 1.3e-05 24.4 0.0 0.0008 18.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCD25961.2 - 2.9e-05 24.1 0.2 0.00037 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 CCD25961.2 - 6.8e-05 22.3 0.0 0.004 16.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.1 CCD25961.2 - 0.00015 21.8 0.1 0.045 13.7 0.0 3.6 3 1 0 3 3 2 1 AAA domain cobW PF02492.14 CCD25961.2 - 0.0005 19.5 0.1 0.001 18.5 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CCD25961.2 - 0.00068 19.1 0.2 0.024 14.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCD25961.2 - 0.002 18.2 0.1 0.013 15.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCD25961.2 - 0.0061 16.8 0.0 0.029 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CCD25961.2 - 0.0066 15.9 0.1 0.27 10.6 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 CCD25961.2 - 0.0078 16.7 0.0 0.8 10.2 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein UPF0079 PF02367.12 CCD25961.2 - 0.014 14.9 1.3 0.19 11.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 MMR_HSR1 PF01926.18 CCD25961.2 - 0.03 14.2 0.4 0.36 10.8 0.0 2.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 CCD25961.2 - 0.047 13.8 0.0 2.4 8.3 0.0 3.1 2 0 0 2 2 2 0 RNA helicase SMC_N PF02463.14 CCD25961.2 - 0.057 12.6 0.0 2.1 7.4 0.0 2.8 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCD25961.2 - 0.063 14.0 0.0 0.26 12.0 0.0 2.0 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 CCD25961.2 - 0.088 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 CCD25961.2 - 0.13 11.2 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_30 PF13604.1 CCD25961.2 - 0.2 11.2 0.3 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CCD25961.2 - 0.21 11.2 0.6 0.47 10.1 0.1 1.8 2 0 0 2 2 2 0 NACHT domain GalP_UDP_transf PF01087.17 CCD25962.2 - 3e-65 219.7 0.4 4.1e-65 219.2 0.3 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CCD25962.2 - 3.4e-64 215.3 0.5 7.3e-64 214.3 0.1 1.7 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain WG_beta_rep PF14903.1 CCD25962.2 - 0.033 14.4 0.1 0.14 12.4 0.0 2.1 1 0 0 1 1 1 0 WG containing repeat HIT PF01230.18 CCD25962.2 - 0.095 13.2 0.0 0.34 11.4 0.0 2.0 2 0 0 2 2 2 0 HIT domain ParA PF10609.4 CCD25963.2 - 2.7e-37 126.4 0.0 5.1e-37 125.6 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCD25963.2 - 2.6e-16 59.6 0.0 4e-16 59.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CCD25963.2 - 2.3e-08 33.4 0.0 8e-08 31.6 0.0 1.7 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 CCD25963.2 - 7.6e-06 25.1 0.1 3.7e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 CCD25963.2 - 1.8e-05 24.6 0.0 0.00036 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CCD25963.2 - 0.0039 16.0 0.1 0.0064 15.2 0.1 1.3 1 0 0 1 1 1 1 ArgK protein Fer4_NifH PF00142.13 CCD25963.2 - 0.005 16.0 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YhjQ PF06564.7 CCD25963.2 - 0.031 13.6 0.1 0.087 12.1 0.0 1.7 1 1 0 1 1 1 0 YhjQ protein APS_kinase PF01583.15 CCD25963.2 - 0.038 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase MobB PF03205.9 CCD25963.2 - 0.091 12.4 0.2 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Gti1_Pac2 PF09729.4 CCD25964.2 - 2.7e-54 183.5 1.6 2.7e-54 183.5 1.1 3.7 2 1 0 2 2 2 1 Gti1/Pac2 family AAA PF00004.24 CCD25965.2 - 2.3e-38 131.3 0.0 7.4e-38 129.7 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CCD25965.2 - 1.8e-06 27.7 0.3 0.00068 19.4 0.0 3.4 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 CCD25965.2 - 6.5e-05 23.0 0.1 0.00069 19.7 0.0 2.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCD25965.2 - 0.00019 20.5 0.0 0.00042 19.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCD25965.2 - 0.0014 18.6 0.1 0.07 13.1 0.0 3.0 1 1 2 3 3 3 1 AAA ATPase domain TIP49 PF06068.8 CCD25965.2 - 0.0018 17.0 0.0 0.0044 15.7 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 CCD25965.2 - 0.0022 17.7 0.1 0.014 15.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CCD25965.2 - 0.0033 16.8 0.2 0.31 10.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCD25965.2 - 0.0038 16.6 0.0 0.0099 15.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CCD25965.2 - 0.0041 16.2 0.8 0.013 14.6 0.1 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CCD25965.2 - 0.0072 16.2 0.0 0.072 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCD25965.2 - 0.012 15.3 0.0 0.034 13.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 CCD25965.2 - 0.016 15.5 0.9 0.15 12.3 0.0 3.1 2 2 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CCD25965.2 - 0.022 14.6 2.2 0.08 12.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_17 PF13207.1 CCD25965.2 - 0.027 15.2 0.1 0.24 12.1 0.1 2.7 1 1 0 1 1 1 0 AAA domain Chromo PF00385.19 CCD25965.2 - 0.052 13.2 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.1 CCD25965.2 - 0.1 12.5 0.2 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain bZIP_1 PF00170.16 CCD25967.2 - 3.5e-08 33.2 11.7 6.9e-08 32.3 8.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCD25967.2 - 1.1e-05 25.2 11.2 2.1e-05 24.2 7.8 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CCD25967.2 - 0.038 14.2 5.5 0.078 13.2 3.8 1.5 1 0 0 1 1 1 0 bZIP Maf transcription factor Herpes_LAMP2 PF06126.6 CCD25967.2 - 0.058 11.7 0.1 0.081 11.3 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Erg28 PF03694.8 CCD25969.2 - 1.6e-44 150.4 3.3 1.9e-44 150.1 2.3 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF308 PF03729.8 CCD25969.2 - 0.06 13.3 1.3 0.46 10.5 0.2 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) MtN3_slv PF03083.11 CCD25969.2 - 0.11 12.3 4.0 0.092 12.6 1.3 1.9 1 1 1 2 2 2 0 Sugar efflux transporter for intercellular exchange SNF2_N PF00176.18 CCD25970.2 - 1.2e-70 237.7 0.1 2.1e-70 236.8 0.1 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCD25970.2 - 2.4e-17 62.5 0.0 4.6e-16 58.4 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD25970.2 - 1.7e-06 27.6 0.0 3.9e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWIRM PF04433.12 CCD25971.2 - 3.7e-32 110.2 2.5 1.5e-31 108.3 0.1 2.9 3 0 0 3 3 3 1 SWIRM domain ZZ PF00569.12 CCD25971.2 - 3.1e-12 45.8 4.2 4.7e-12 45.2 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CCD25971.2 - 2.7e-06 27.3 0.1 6.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCD25971.2 - 6.8e-06 26.0 1.4 7.8e-05 22.6 0.1 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain Elf1 PF05129.8 CCD25971.2 - 0.0086 15.7 0.7 0.02 14.5 0.5 1.5 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like STAG PF08514.6 CCD25972.2 - 3.8e-07 29.8 2.7 1.3e-05 24.8 1.8 3.2 1 1 0 1 1 1 1 STAG domain rve_3 PF13683.1 CCD25972.2 - 0.012 15.0 0.4 0.12 11.8 0.0 2.9 4 0 0 4 4 4 0 Integrase core domain HEAT PF02985.17 CCD25972.2 - 0.078 13.0 0.1 35 4.8 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat APC_CDC26 PF10471.4 CCD25973.2 - 1.7e-10 41.4 1.4 2.3e-10 41.0 0.8 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 PBP5_C PF07943.8 CCD25973.2 - 0.19 11.7 0.8 0.32 11.0 0.5 1.5 1 1 0 1 1 1 0 Penicillin-binding protein 5, C-terminal domain RNA_pol_A_bac PF01000.21 CCD25975.2 - 9.9e-34 115.8 0.5 3.5e-33 114.0 0.1 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CCD25975.2 - 9.4e-15 53.4 0.0 1.3e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain BSP_II PF05432.6 CCD25976.2 - 0.021 14.1 15.4 0.032 13.5 10.7 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) HLH PF00010.21 CCD25977.2 - 2.4e-11 43.1 1.4 7.6e-11 41.5 1.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UCR_hinge PF02320.11 CCD25978.2 - 3.6e-18 65.2 1.6 7.7e-18 64.1 1.1 1.6 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Fmp27_WPPW PF10359.4 CCD25978.2 - 0.11 10.8 5.8 0.12 10.7 4.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spore_coat_CotO PF14153.1 CCD25978.2 - 0.13 11.7 8.1 0.14 11.6 5.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO DUF3450 PF11932.3 CCD25978.2 - 0.14 11.3 2.8 0.16 11.2 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) CDC45 PF02724.9 CCD25978.2 - 0.18 9.7 11.9 0.19 9.7 8.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.8 CCD25978.2 - 0.24 10.9 22.6 0.44 10.1 15.6 1.5 1 1 0 1 1 1 0 Sigma-70, non-essential region Merozoite_SPAM PF07133.6 CCD25978.2 - 0.27 11.1 23.8 0.35 10.7 16.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) YqfQ PF14181.1 CCD25978.2 - 0.27 11.2 3.7 0.26 11.2 2.6 1.2 1 0 0 1 1 1 0 YqfQ-like protein CotH PF08757.6 CCD25978.2 - 0.28 10.4 4.3 0.38 9.9 3.0 1.3 1 0 0 1 1 1 0 CotH protein HSP90 PF00183.13 CCD25978.2 - 0.33 9.2 15.0 0.32 9.3 10.4 1.1 1 0 0 1 1 1 0 Hsp90 protein RasGAP PF00616.14 CCD25978.2 - 0.46 10.1 6.8 1.5 8.4 4.7 1.8 1 1 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Tim54 PF11711.3 CCD25978.2 - 0.48 8.9 5.9 0.49 8.9 4.1 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Ycf1 PF05758.7 CCD25978.2 - 0.6 7.7 9.4 0.6 7.7 6.5 1.0 1 0 0 1 1 1 0 Ycf1 Daxx PF03344.10 CCD25978.2 - 0.67 8.3 22.0 0.78 8.1 15.2 1.1 1 0 0 1 1 1 0 Daxx Family VID27 PF08553.5 CCD25978.2 - 0.81 7.8 15.1 0.9 7.6 10.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein Bap31 PF05529.7 CCD25978.2 - 0.82 9.1 6.0 1 8.7 4.1 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PP_M1 PF03012.9 CCD25978.2 - 1.1 8.6 8.6 0.78 9.0 4.7 1.6 1 1 1 2 2 2 0 Phosphoprotein DUF506 PF04720.7 CCD25978.2 - 1.2 8.7 7.1 1.4 8.4 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Nop14 PF04147.7 CCD25978.2 - 1.4 6.7 20.5 1.4 6.7 14.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF3530 PF12048.3 CCD25978.2 - 2 7.3 4.9 2.4 7.0 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Adeno_terminal PF02459.10 CCD25978.2 - 2.3 6.2 10.8 2.5 6.1 7.5 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein TRAP_alpha PF03896.11 CCD25978.2 - 2.6 6.9 13.2 3 6.7 9.1 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.6 CCD25978.2 - 2.8 5.9 10.9 2.7 5.9 7.5 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.7 CCD25978.2 - 3.3 6.7 19.6 3.9 6.5 13.6 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DDRGK PF09756.4 CCD25978.2 - 3.6 6.9 19.6 4.9 6.5 13.6 1.2 1 0 0 1 1 1 0 DDRGK domain RNA_pol_Rpc4 PF05132.9 CCD25978.2 - 3.6 7.5 8.0 5.2 7.0 5.6 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sporozoite_P67 PF05642.6 CCD25978.2 - 3.9 5.2 7.8 4.3 5.0 5.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3347 PF11827.3 CCD25978.2 - 4.4 7.2 7.5 17 5.3 5.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3347) SDA1 PF05285.7 CCD25978.2 - 5.2 6.2 19.2 5.8 6.1 13.3 1.1 1 0 0 1 1 1 0 SDA1 HSP70 PF00012.15 CCD25978.2 - 6 4.6 10.5 6.7 4.4 7.3 1.0 1 0 0 1 1 1 0 Hsp70 protein BUD22 PF09073.5 CCD25978.2 - 7.1 5.5 19.9 8.1 5.3 13.8 1.0 1 0 0 1 1 1 0 BUD22 DNA_pol_phi PF04931.8 CCD25978.2 - 7.4 4.2 24.2 7.2 4.2 16.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi V_ATPase_I PF01496.14 CCD25978.2 - 8 4.1 8.6 8.6 4.0 6.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HBS1_N PF08938.5 CCD25978.2 - 8.8 6.5 23.6 0.2 11.8 11.4 1.9 2 0 0 2 2 2 0 HBS1 N-terminus Ribosomal_L29e PF01779.12 CCD25979.2 - 2.1e-24 85.0 8.8 3e-24 84.5 6.1 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family RRM_1 PF00076.17 CCD25980.2 - 3e-16 58.8 0.1 1.2e-08 34.4 0.0 3.4 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD25980.2 - 1.1e-14 54.1 0.0 1.8e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD25980.2 - 1.9e-08 33.9 0.0 5e-07 29.4 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L2_C PF03947.13 CCD25981.2 - 2.5e-41 140.5 2.1 3.7e-41 139.9 1.5 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCD25981.2 - 2.8e-13 49.6 0.2 6.6e-13 48.4 0.1 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SMC_N PF02463.14 CCD25982.2 - 3.3e-64 216.1 31.6 2.5e-62 209.9 21.9 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCD25982.2 - 9.8e-20 70.7 0.9 2.3e-19 69.5 0.0 2.2 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCD25982.2 - 1.9e-09 37.9 42.9 3e-06 27.4 0.4 4.7 3 1 1 4 4 4 3 AAA domain AAA_23 PF13476.1 CCD25982.2 - 4.9e-07 30.2 42.1 4.9e-07 30.2 29.2 7.1 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 CCD25982.2 - 2.1e-05 23.9 0.1 6.9e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 CCD25982.2 - 0.062 13.5 0.1 0.062 13.5 0.1 5.9 3 3 0 4 4 4 0 ABC transporter FAD_binding_1 PF00667.15 CCD25983.2 - 8.5e-62 208.4 0.0 1.6e-61 207.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CCD25983.2 - 5.1e-09 36.6 0.0 1.6e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain CENP-B_dimeris PF09026.5 CCD25983.2 - 0.1 12.8 4.6 0.31 11.3 3.2 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain EST1_DNA_bind PF10373.4 CCD25985.2 - 1e-31 110.2 0.8 1e-31 110.2 0.5 2.1 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CCD25985.2 - 7e-10 39.0 1.1 2.3e-09 37.3 0.8 1.9 1 0 0 1 1 1 1 Telomerase activating protein Est1 Topoisom_bac PF01131.15 CCD25986.2 - 8.4e-90 301.4 0.0 1.1e-89 301.1 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CCD25986.2 - 3.9e-19 68.4 0.0 7.6e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Transp_cyt_pur PF02133.10 CCD25987.2 - 2.5e-71 240.5 38.8 3.1e-71 240.2 26.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SPC25 PF06703.6 CCD25987.2 - 0.014 14.9 4.6 0.27 10.7 0.3 2.4 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF3754 PF12576.3 CCD25987.2 - 0.067 12.8 1.3 0.14 11.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) zf-LITAF-like PF10601.4 CCD25987.2 - 0.45 10.4 0.1 0.45 10.4 0.0 3.0 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain Rogdi_lz PF10259.4 CCD25988.2 - 1.6e-77 260.3 9.8 7.2e-77 258.1 6.8 1.8 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein SR-25 PF10500.4 CCD25988.2 - 0.56 9.6 4.9 1.2 8.5 3.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FHA PF00498.21 CCD25989.2 - 7.1e-17 61.2 0.5 4.1e-16 58.8 0.1 2.5 2 0 0 2 2 2 1 FHA domain BPL_LplA_LipB PF03099.14 CCD25990.2 - 6.4e-17 61.7 0.0 1.1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PI3Ka PF00613.15 CCD25991.2 - 3e-74 248.1 2.5 4.9e-74 247.5 1.8 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CCD25991.2 - 9.5e-46 156.1 0.0 1.2e-44 152.5 0.0 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 CCD25991.2 - 2.2e-21 76.1 0.1 7.1e-21 74.4 0.1 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF221 PF02714.10 CCD25992.2 - 8.1e-100 333.8 19.4 8.1e-100 333.8 13.5 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCD25992.2 - 2.6e-39 134.2 4.2 2.6e-39 134.2 2.9 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CCD25992.2 - 6.5e-15 55.4 0.0 1.4e-14 54.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Arv1 PF04161.8 CCD25993.2 - 1.6e-78 263.3 11.9 2.3e-78 262.8 8.3 1.2 1 0 0 1 1 1 1 Arv1-like family ATP_bind_1 PF03029.12 CCD25994.2 - 1.2e-86 290.1 0.0 1.3e-86 289.9 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CCD25994.2 - 0.00016 22.5 0.0 0.00041 21.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CCD25994.2 - 0.00017 21.1 0.0 0.00035 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain ArgK PF03308.11 CCD25994.2 - 0.00083 18.2 0.0 0.0016 17.2 0.0 1.3 1 0 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 CCD25994.2 - 0.0019 18.1 0.0 0.0034 17.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 CCD25994.2 - 0.0091 16.1 0.0 0.027 14.6 0.0 1.8 2 0 0 2 2 1 1 RNA helicase GTP_EFTU PF00009.22 CCD25994.2 - 0.0092 15.4 0.0 0.18 11.2 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CCD25994.2 - 0.0096 16.2 0.0 0.017 15.4 0.0 1.4 1 0 0 1 1 1 1 ABC transporter DUF87 PF01935.12 CCD25994.2 - 0.011 15.5 0.0 0.024 14.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 T2SE PF00437.15 CCD25994.2 - 0.011 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CCD25994.2 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 CCD25994.2 - 0.016 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.9 CCD25994.2 - 0.017 14.0 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.1 CCD25994.2 - 0.018 14.6 0.0 0.048 13.2 0.0 1.7 2 0 0 2 2 1 0 AAA domain Viral_helicase1 PF01443.13 CCD25994.2 - 0.026 14.0 0.0 0.31 10.5 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 CCD25994.2 - 0.027 14.6 0.0 0.052 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCD25994.2 - 0.029 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CCD25994.2 - 0.05 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 CCD25994.2 - 0.053 12.7 0.0 0.097 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCD25994.2 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 CCD25994.2 - 0.065 12.6 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 CCD25994.2 - 0.065 12.9 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 CCD25994.2 - 0.073 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCD25994.2 - 0.077 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 CCD25994.2 - 0.079 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 CCD25994.2 - 0.093 12.2 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCD25994.2 - 0.095 13.0 0.0 0.3 11.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 CCD25994.2 - 0.12 11.3 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin Sigma54_activat PF00158.21 CCD25994.2 - 0.13 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain PPV_E1_C PF00519.12 CCD25994.2 - 0.14 10.7 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AIG1 PF04548.11 CCD25994.2 - 0.15 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AAA_5 PF07728.9 CCD25994.2 - 0.15 11.8 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CCD25995.2 - 3.2e-188 625.4 0.5 3.7e-188 625.2 0.4 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CCD25995.2 - 7.6e-09 34.9 1.6 7e-05 21.9 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 CCD25995.2 - 3.3e-08 33.7 0.8 8.5e-05 22.7 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CCD25995.2 - 0.0012 18.8 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCD25995.2 - 0.003 17.5 0.1 0.21 11.5 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 CCD25995.2 - 0.0053 16.4 0.1 0.021 14.5 0.1 2.1 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CCD25995.2 - 0.011 15.6 0.0 0.88 9.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CCD25995.2 - 0.012 14.7 0.1 0.027 13.5 0.1 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 CCD25995.2 - 0.016 14.9 0.2 0.61 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DnaB_C PF03796.10 CCD25995.2 - 0.023 13.5 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 CCD25995.2 - 0.028 13.5 0.1 3.4 6.7 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CPT PF07931.7 CCD25995.2 - 0.035 13.7 0.0 0.087 12.4 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.21 CCD25995.2 - 0.039 13.4 0.0 5.7 6.3 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain Toprim PF01751.17 CCD25995.2 - 0.082 12.8 0.0 0.74 9.8 0.0 2.3 2 1 0 2 2 2 0 Toprim domain Sec1 PF00995.18 CCD25996.2 - 2.1e-141 472.3 8.3 2.4e-141 472.1 5.8 1.0 1 0 0 1 1 1 1 Sec1 family Cpn60_TCP1 PF00118.19 CCD25997.2 - 6.4e-145 483.4 2.7 7.3e-145 483.2 1.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M24 PF00557.19 CCD25998.2 - 3.6e-44 150.8 0.1 4.6e-44 150.4 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 dCMP_cyt_deam_1 PF00383.17 CCD25999.2 - 2.9e-11 42.9 1.7 1.8e-10 40.3 1.2 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 CCD25999.2 - 5.6e-06 25.8 1.1 0.00044 19.6 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases dCMP_cyt_deam_2 PF08211.6 CCD25999.2 - 0.00066 19.6 0.3 0.042 13.8 0.0 2.4 2 1 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region zf-DHHC PF01529.15 CCD26000.2 - 3.9e-36 124.0 7.3 3.9e-36 124.0 5.1 2.4 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF2645 PF10840.3 CCD26000.2 - 0.026 14.6 2.5 0.026 14.6 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2645) ATP_synt_I PF03899.10 CCD26000.2 - 0.055 13.6 3.2 0.094 12.8 0.1 2.4 2 0 0 2 2 2 0 ATP synthase I chain RDD PF06271.7 CCD26000.2 - 0.66 9.8 6.8 3.6 7.4 0.2 2.4 2 0 0 2 2 2 0 RDD family RELT PF12606.3 CCD26000.2 - 0.72 9.0 3.6 2 7.6 2.5 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 PRELI PF04707.9 CCD26001.2 - 1.9e-53 180.2 0.3 3.1e-53 179.5 0.2 1.3 1 0 0 1 1 1 1 PRELI-like family DUP PF00674.13 CCD26002.2 - 4.9e-18 65.0 2.0 9.6e-18 64.1 1.4 1.5 1 0 0 1 1 1 1 DUP family DUF4051 PF13260.1 CCD26002.2 - 0.84 9.0 3.8 0.5 9.7 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) ubiquitin PF00240.18 CCD26003.2 - 1.3e-34 117.3 0.9 2.7e-34 116.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 CCD26003.2 - 1.6e-27 95.0 2.4 2.9e-27 94.2 1.7 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CCD26003.2 - 1e-19 69.9 0.7 1e-19 69.9 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCD26003.2 - 8.6e-06 25.9 0.2 3.9e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCD26003.2 - 0.00011 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCD26003.2 - 0.0012 18.7 0.4 0.0025 17.6 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCD26003.2 - 0.0038 17.3 0.4 0.0049 17.0 0.3 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 CCD26003.2 - 0.017 14.9 0.5 0.025 14.4 0.4 1.3 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 CCD26003.2 - 0.057 13.4 0.2 0.12 12.4 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) DUF2207 PF09972.4 CCD26003.2 - 0.11 11.0 0.4 0.12 10.9 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) A2L_zn_ribbon PF08792.5 CCD26003.2 - 0.12 11.8 1.1 0.21 11.1 0.8 1.4 1 0 0 1 1 1 0 A2L zinc ribbon domain Plexin_cytopl PF08337.7 CCD26003.2 - 0.22 9.8 2.8 4.7 5.4 0.1 2.2 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Sec10 PF07393.6 CCD26004.2 - 6.9e-194 646.0 32.7 9.3e-194 645.5 22.6 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 PseudoU_synth_2 PF00849.17 CCD26005.2 - 3.9e-18 65.8 0.0 7.3e-17 61.6 0.0 2.2 1 1 0 1 1 1 1 RNA pseudouridylate synthase DUP PF00674.13 CCD26006.2 - 7e-22 77.4 1.8 1.2e-21 76.6 1.2 1.4 1 0 0 1 1 1 1 DUP family SdpI PF13630.1 CCD26006.2 - 0.037 13.7 7.3 0.06 13.0 5.1 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family Peptidase_M16 PF00675.15 CCD26007.2 - 4e-53 179.1 0.0 7.5e-53 178.2 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCD26007.2 - 1.6e-36 125.6 0.0 1.8e-35 122.2 0.0 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain BHD_1 PF10403.4 CCD26008.2 - 3.3e-14 52.1 0.0 7.4e-14 51.0 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CCD26008.2 - 8.7e-11 41.9 1.0 2.6e-10 40.4 0.7 1.9 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 BHD_3 PF10405.4 CCD26008.2 - 6.7e-08 32.1 0.1 1.9e-07 30.6 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 CCD26008.2 - 2.2e-07 30.3 0.3 6.1e-07 28.9 0.2 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Vps39_1 PF10366.4 CCD26008.2 - 0.053 13.5 1.2 6 6.9 0.1 3.0 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 1 Vmethyltransf_C PF08456.5 CCD26009.2 - 0.066 12.6 1.5 0.14 11.5 1.0 1.5 1 0 0 1 1 1 0 Viral methyltransferase C-terminal DUF3802 PF12290.3 CCD26009.2 - 0.085 13.1 4.0 0.074 13.3 1.5 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3802) TMEM51 PF15345.1 CCD26009.2 - 0.27 10.9 0.1 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 51 AMP-binding PF00501.23 CCD26010.2 - 5.8e-85 285.2 0.0 7e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCD26010.2 - 1.4e-17 64.4 0.0 2.7e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NUDIX PF00293.23 CCD26011.2 - 2.2e-19 69.4 0.0 5.6e-19 68.1 0.0 1.7 1 1 1 2 2 2 1 NUDIX domain Stb3 PF10330.4 CCD26012.2 - 3.8e-31 106.6 0.0 1.1e-30 105.1 0.0 1.7 1 0 0 1 1 1 1 Putative Sin3 binding protein DUF2415 PF10313.4 CCD26013.2 - 1.6e-21 75.7 0.7 3.8e-21 74.4 0.5 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Pep3_Vps18 PF05131.9 CCD26014.2 - 1.2e-35 122.0 0.1 1.2e-35 122.0 0.1 2.5 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CCD26014.2 - 8.7e-07 28.6 20.1 2.2e-06 27.3 4.5 4.3 4 0 0 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.4 CCD26014.2 - 0.00014 21.9 1.7 0.00014 21.9 1.2 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 CCD26014.2 - 0.00082 19.1 3.9 0.0016 18.2 2.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCD26014.2 - 0.00082 19.0 5.1 0.0016 18.1 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain WD40 PF00400.27 CCD26014.2 - 0.00099 18.9 0.5 2.6 8.0 0.0 3.0 2 1 0 2 2 2 2 WD domain, G-beta repeat DUF2191 PF09957.4 CCD26014.2 - 0.074 12.8 0.0 0.25 11.1 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2191) zf-C3HC4_2 PF13923.1 CCD26014.2 - 0.32 11.0 4.3 0.67 10.0 3.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Med27 PF11571.3 CCD26014.2 - 2.1 8.5 9.6 10 6.2 0.1 3.8 3 1 0 3 3 3 0 Mediator complex subunit 27 LSM PF01423.17 CCD26015.2 - 7.7e-13 47.7 0.3 8.5e-13 47.6 0.2 1.0 1 0 0 1 1 1 1 LSM domain Ax_dynein_light PF10211.4 CCD26016.2 - 0.0092 15.8 0.4 0.018 14.9 0.1 1.6 1 1 0 1 1 1 1 Axonemal dynein light chain FAA_hydrolase_N PF09298.6 CCD26016.2 - 0.14 12.1 0.5 0.18 11.8 0.3 1.3 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Spermine_synth PF01564.12 CCD26017.2 - 1.1e-89 299.5 0.3 1.4e-89 299.2 0.2 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_23 PF13489.1 CCD26017.2 - 0.00072 19.3 0.0 0.0027 17.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD26017.2 - 0.0029 18.1 0.0 0.0059 17.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCD26017.2 - 0.0076 15.8 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCD26017.2 - 0.084 13.3 0.0 0.2 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain RNase_H2-Ydr279 PF09468.5 CCD26018.2 - 0.4 9.8 10.8 0.079 12.1 5.1 1.6 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Glyco_hydro_81 PF03639.8 CCD26019.2 - 3.7e-223 742.4 22.1 4.7e-223 742.1 15.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 ATP_bind_4 PF01902.12 CCD26021.2 - 1.6e-36 125.7 0.0 6.8e-36 123.6 0.0 2.0 1 1 0 1 1 1 1 ATP-binding region Ribonuc_L-PSP PF01042.16 CCD26021.2 - 5.8e-16 58.3 0.0 3.4e-07 30.0 0.0 2.7 2 0 0 2 2 2 2 Endoribonuclease L-PSP DUF968 PF06147.6 CCD26023.1 - 0.01 15.7 0.2 0.019 14.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF968) MU117 PF15474.1 CCD26023.1 - 0.08 13.4 1.7 0.22 12.0 0.7 2.0 2 1 0 2 2 2 0 Meiotically up-regulated gene family Na_H_Exchanger PF00999.16 CCD26026.2 - 1.5e-81 273.8 24.9 1.9e-81 273.5 17.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 CCD26026.2 - 6.4e-61 206.9 42.9 9.1e-61 206.4 29.2 1.6 1 1 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Methyltransf_16 PF10294.4 CCD26028.2 - 1.8e-06 27.4 4.2 0.00033 20.1 1.3 2.9 2 1 0 2 2 2 2 Putative methyltransferase BTV_NS2 PF04514.7 CCD26028.2 - 0.25 10.1 6.7 1.4 7.7 1.1 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 NST1 PF13945.1 CCD26028.2 - 0.39 10.7 11.0 0.072 13.1 0.8 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator zf-CCCH PF00642.19 CCD26029.2 - 1.2e-15 56.7 14.2 5.7e-08 32.2 0.6 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3363 PF11843.3 CCD26029.2 - 0.097 11.2 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3363) zf-CCCH_2 PF14608.1 CCD26029.2 - 1.7 8.7 13.1 1.7 8.7 0.2 2.5 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Pheromone PF08015.6 CCD26029.2 - 2.3 9.1 9.1 2.7 8.9 1.0 2.6 2 0 0 2 2 2 0 Fungal mating-type pheromone Slx4 PF09494.5 CCD26030.2 - 2.4e-14 52.7 0.5 6.5e-14 51.4 0.3 1.8 1 0 0 1 1 1 1 Slx4 endonuclease Choline_kinase PF01633.15 CCD26031.2 - 1.9e-66 223.6 0.2 3.1e-66 222.9 0.1 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 CCD26031.2 - 2.4e-15 55.7 0.0 5.7e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 CCD26031.2 - 1.5e-05 24.8 0.0 0.011 15.4 0.0 2.8 2 1 0 2 2 2 2 Phosphotransferase enzyme family Mucin PF01456.12 CCD26031.2 - 0.057 13.1 26.7 0.24 11.1 0.3 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein EcKinase PF02958.15 CCD26031.2 - 0.21 10.6 2.5 27 3.7 0.1 3.1 3 0 0 3 3 3 0 Ecdysteroid kinase Corona_nucleoca PF00937.13 CCD26031.2 - 3.8 6.3 6.5 6.4 5.6 4.5 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein HVSL PF09749.4 CCD26032.2 - 8.1e-26 90.4 2.8 9.8e-26 90.2 2.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein CPDase PF07823.6 CCD26032.2 - 0.099 12.1 1.0 0.21 11.0 0.4 1.7 1 1 1 2 2 2 0 Cyclic phosphodiesterase-like protein zf-C2H2 PF00096.21 CCD26033.2 - 1.8e-07 31.1 8.6 0.0045 17.2 0.4 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD26033.2 - 0.0025 18.0 6.8 0.24 11.8 0.3 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD26033.2 - 0.0026 17.9 0.4 0.0026 17.9 0.3 3.6 3 1 0 3 3 3 1 Zinc-finger double domain zf-TRAF PF02176.13 CCD26033.2 - 0.0043 17.4 1.2 0.0084 16.4 0.9 1.5 1 0 0 1 1 1 1 TRAF-type zinc finger Zip PF02535.17 CCD26034.2 - 9.5e-67 225.2 0.2 2.8e-66 223.6 0.1 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter UNC-50 PF05216.8 CCD26034.2 - 0.0077 15.4 2.8 0.034 13.3 1.6 2.0 2 0 0 2 2 2 1 UNC-50 family YniB PF14002.1 CCD26034.2 - 0.053 12.9 0.3 0.17 11.3 0.2 1.8 1 0 0 1 1 1 0 YniB-like protein BSP_II PF05432.6 CCD26034.2 - 9.6 5.3 14.1 15 4.7 9.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) WD40 PF00400.27 CCD26035.2 - 1.6e-72 237.0 32.0 4.4e-10 39.0 0.3 11.7 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 CCD26035.2 - 8.1e-26 90.0 0.2 1.6e-25 89.1 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CCD26035.2 - 6.8e-06 24.4 9.1 0.0012 17.1 0.0 5.1 4 2 0 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.6 CCD26035.2 - 0.011 15.4 1.1 0.33 10.6 0.0 3.9 4 2 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 CCD26035.2 - 0.18 10.9 6.1 1.6 7.8 0.0 4.5 6 0 0 6 6 6 0 TUP1-like enhancer of split Cullin_binding PF03556.10 CCD26036.2 - 2.7e-29 101.6 9.6 4.8e-24 84.7 4.3 2.5 2 0 0 2 2 2 2 Cullin binding UBA_4 PF14555.1 CCD26036.2 - 2.7e-06 26.8 0.8 1.9e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 UBA-like domain DUF869 PF05911.6 CCD26036.2 - 0.029 12.6 0.9 0.032 12.4 0.6 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) HARP PF07443.8 CCD26036.2 - 0.2 11.0 4.0 0.3 10.4 0.1 2.5 2 0 0 2 2 2 0 HepA-related protein (HARP) APC2 PF08672.6 CCD26037.2 - 1.1e-19 70.4 0.6 8.4e-19 67.5 0.2 2.9 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 FANCI_S1 PF14675.1 CCD26037.2 - 0.0087 15.4 0.1 0.026 13.8 0.1 1.8 1 0 0 1 1 1 1 FANCI solenoid 1 GATase PF00117.23 CCD26038.2 - 1.5e-10 40.8 0.0 3.8e-10 39.5 0.0 1.5 1 1 1 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCD26038.2 - 0.002 17.6 0.0 0.0031 17.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 Asp PF00026.18 CCD26039.2 - 4.9e-71 239.5 14.4 4.9e-71 239.5 10.0 1.9 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCD26039.2 - 7.3e-09 35.7 1.8 7.3e-09 35.7 1.2 3.6 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCD26039.2 - 0.093 12.2 0.1 0.37 10.3 0.1 2.1 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal zf-RING_2 PF13639.1 CCD26040.2 - 1.6e-10 40.6 4.5 2.5e-09 36.8 0.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CCD26040.2 - 1.1e-06 28.5 0.5 2.5e-05 24.3 0.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 CCD26040.2 - 6.4e-05 22.7 1.7 6.4e-05 22.7 1.2 1.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCD26040.2 - 7.1e-05 22.4 0.3 7.1e-05 22.4 0.2 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CCD26040.2 - 8.2e-05 22.5 1.2 8.2e-05 22.5 0.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCD26040.2 - 0.00012 21.7 2.6 0.0014 18.2 0.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCD26040.2 - 0.00036 20.1 2.5 0.00068 19.2 0.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCD26040.2 - 0.0012 18.4 3.7 0.0023 17.5 0.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCD26040.2 - 0.028 14.2 0.5 0.059 13.2 0.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 CCD26040.2 - 0.048 13.2 0.6 0.11 12.0 0.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Mod_r PF07200.8 CCD26041.2 - 2.8e-14 53.3 14.4 6.2e-14 52.1 10.0 1.5 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein SCO1-SenC PF02630.9 CCD26041.2 - 0.0074 15.9 1.1 0.025 14.1 0.7 2.0 1 1 0 1 1 1 1 SCO1/SenC UBN2 PF14223.1 CCD26041.2 - 0.0089 15.8 0.7 0.087 12.6 0.1 2.5 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type DivIC PF04977.10 CCD26041.2 - 0.16 11.4 2.8 0.11 11.9 0.5 1.8 2 0 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 CCD26041.2 - 0.16 11.9 3.0 1.3 9.0 0.7 2.9 3 0 0 3 3 3 0 bZIP transcription factor Spc24 PF08286.6 CCD26041.2 - 0.23 11.1 4.8 0.27 10.9 0.4 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 UPF0449 PF15136.1 CCD26041.2 - 0.27 11.4 3.3 1.4 9.2 0.2 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 TPR_MLP1_2 PF07926.7 CCD26041.2 - 0.32 10.7 5.8 0.72 9.5 4.0 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 CCD26041.2 - 0.71 9.4 7.7 0.096 12.2 1.1 2.1 2 0 0 2 2 2 0 IncA protein DUF972 PF06156.8 CCD26041.2 - 0.91 9.9 7.5 11 6.3 5.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF4298 PF14131.1 CCD26041.2 - 1.1 9.1 6.8 0.17 11.7 1.4 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) Abhydrolase_2 PF02230.11 CCD26042.2 - 3.2e-54 183.6 0.0 3.6e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 CCD26042.2 - 2e-08 34.0 0.0 2.6e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CCD26042.2 - 3.5e-08 33.1 0.0 6.4e-08 32.2 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 CCD26042.2 - 1.6e-07 31.4 0.0 5.7e-07 29.6 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family TPR_14 PF13428.1 CCD26043.2 - 7.6e-16 57.1 0.2 0.016 15.7 0.0 8.4 6 2 4 10 10 10 3 Tetratricopeptide repeat HAT PF02184.11 CCD26043.2 - 1.7e-09 37.2 31.9 0.00023 20.8 0.4 8.2 10 0 0 10 10 10 4 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 CCD26043.2 - 2.1e-09 37.8 0.0 0.17 12.5 0.0 5.5 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCD26043.2 - 5.3e-07 29.8 0.0 3.4 8.0 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCD26043.2 - 1.9e-06 27.3 10.2 0.53 10.3 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCD26043.2 - 4e-05 23.1 5.7 0.42 10.3 0.1 4.6 5 0 0 5 5 5 2 TPR repeat TPR_12 PF13424.1 CCD26043.2 - 0.00046 20.0 3.0 1.9 8.5 0.0 5.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCD26043.2 - 0.0022 17.6 8.6 2.3 8.2 0.4 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCD26043.2 - 0.0045 16.5 5.6 7.3 6.3 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCD26043.2 - 0.0098 15.6 12.2 3.1 7.8 0.4 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 CCD26043.2 - 0.031 14.0 20.0 0.062 13.0 1.0 6.2 5 2 2 7 7 7 0 U3 small nucleolar RNA-associated protein 6 TPR_17 PF13431.1 CCD26043.2 - 0.36 11.1 3.7 9 6.7 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat KH_3 PF13014.1 CCD26044.2 - 2.7e-07 30.1 0.1 3e-06 26.7 0.0 2.5 2 0 0 2 2 2 1 KH domain KH_1 PF00013.24 CCD26044.2 - 5.4e-07 29.1 0.1 1.2e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.18 CCD26044.2 - 1.5e-05 24.6 9.4 0.00026 20.7 0.6 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CCD26044.2 - 0.0035 17.0 8.1 0.041 13.6 1.4 2.7 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 CCD26044.2 - 0.058 13.0 6.8 1 9.0 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 CCD26044.2 - 0.92 9.2 8.3 1.7 8.3 1.4 2.8 1 1 1 2 2 2 0 Zinc knuckle eIF3g PF12353.3 CCD26044.2 - 6.5 6.6 7.8 21 5.0 0.2 2.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G CPSF100_C PF13299.1 CCD26045.2 - 2.3e-31 109.1 0.3 2.3e-31 109.1 0.2 3.3 3 2 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CCD26045.2 - 6.1e-10 39.1 0.1 1.8e-08 34.3 0.0 2.7 1 1 1 2 2 2 2 Beta-Casp domain Avl9 PF09794.4 CCD26046.2 - 4.8e-146 486.0 3.1 7.9e-146 485.3 2.2 1.4 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 CCD26046.2 - 4.8e-08 32.6 1.9 0.00072 19.2 0.0 3.1 2 1 0 3 3 3 2 Stabilization of polarity axis DENN PF02141.16 CCD26046.2 - 4.4e-06 26.5 1.5 3e-05 23.8 1.0 2.2 1 1 0 1 1 1 1 DENN (AEX-3) domain DUF2347 PF09804.4 CCD26046.2 - 1.5e-05 24.4 1.3 1.5e-05 24.4 0.9 4.7 3 2 0 3 3 3 1 Uncharacterized conserved protein (DUF2347) Pkinase PF00069.20 CCD26047.2 - 6.3e-69 232.0 0.0 9.4e-69 231.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26047.2 - 1.7e-30 105.9 0.0 3e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCD26047.2 - 5e-05 22.4 0.1 0.00018 20.6 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD26047.2 - 0.00013 21.7 0.5 0.0019 18.0 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCD26047.2 - 0.00057 18.9 0.0 0.073 12.0 0.0 2.3 1 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 CCD26047.2 - 0.07 12.4 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 RIO1 family Flocculin_t3 PF13928.1 CCD26049.2 - 4.1e-13 49.2 19.8 4.1e-13 49.2 13.7 2.1 1 1 1 2 2 2 1 Flocculin type 3 repeat Spore-coat_CotD PF11122.3 CCD26049.2 - 0.013 15.7 4.6 0.016 15.4 3.2 1.2 1 0 0 1 1 1 0 Inner spore coat protein D REC114-like PF15165.1 CCD26049.2 - 0.077 12.7 1.7 0.09 12.5 1.2 1.0 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Gram_pos_anchor PF00746.16 CCD26049.2 - 0.13 12.1 4.4 0.23 11.3 3.1 1.4 1 0 0 1 1 1 0 Gram positive anchor Redoxin PF08534.5 CCD26050.2 - 4.5e-30 104.1 0.9 5.1e-30 103.9 0.6 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CCD26050.2 - 6.8e-08 32.2 0.1 1e-07 31.6 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family BTB_2 PF02214.17 CCD26051.2 - 7.3e-07 29.3 6.9 0.0021 18.1 0.5 3.4 3 1 0 3 3 3 2 BTB/POZ domain SR-25 PF10500.4 CCD26051.2 - 8.8 5.7 29.6 0.042 13.3 14.0 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RNase_T PF00929.19 CCD26052.2 - 1.2e-18 67.9 0.1 2.4e-18 66.9 0.1 1.5 1 0 0 1 1 1 1 Exonuclease CHORD PF04968.7 CCD26052.2 - 0.0038 17.4 5.3 0.0087 16.2 3.7 1.6 1 0 0 1 1 1 1 CHORD DNA_pol_A_exo1 PF01612.15 CCD26052.2 - 0.019 14.4 0.6 0.21 11.0 0.4 2.5 1 1 0 1 1 1 0 3'-5' exonuclease AAA_5 PF07728.9 CCD26053.2 - 1.3e-126 416.9 1.7 3.2e-21 75.5 0.0 9.9 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCD26053.2 - 2.6e-31 107.9 0.0 1e-10 41.3 0.0 8.0 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CCD26053.2 - 7e-25 87.7 2.7 0.00079 19.6 0.0 7.8 7 0 0 7 7 7 5 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCD26053.2 - 5.4e-19 68.2 0.2 0.001 18.5 0.0 6.2 6 0 0 6 6 6 4 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 CCD26053.2 - 1e-18 67.7 2.0 0.00026 21.0 0.0 8.2 9 0 0 9 9 8 3 Sigma-54 interaction domain AAA_14 PF13173.1 CCD26053.2 - 1.1e-17 64.1 7.5 0.00084 19.2 0.0 9.2 8 1 0 8 8 7 3 AAA domain AAA_16 PF13191.1 CCD26053.2 - 6.2e-17 62.1 15.5 0.017 15.1 0.0 9.6 9 2 1 10 10 8 5 AAA ATPase domain AAA_22 PF13401.1 CCD26053.2 - 2.4e-16 60.0 5.5 0.12 12.5 0.0 9.1 9 0 0 9 9 7 4 AAA domain Zeta_toxin PF06414.7 CCD26053.2 - 8.2e-16 57.6 2.2 0.0054 15.8 0.0 7.9 8 0 0 8 8 8 5 Zeta toxin AAA_33 PF13671.1 CCD26053.2 - 1.8e-14 53.8 0.0 0.18 11.6 0.1 7.3 6 2 0 6 6 6 3 AAA domain T2SE PF00437.15 CCD26053.2 - 1.9e-14 53.2 6.2 0.018 13.9 0.4 6.1 6 0 0 6 6 6 3 Type II/IV secretion system protein DUF258 PF03193.11 CCD26053.2 - 7.4e-13 47.9 6.4 0.094 11.8 0.0 7.2 7 0 0 7 7 7 3 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCD26053.2 - 1.3e-12 48.6 30.7 0.049 14.4 0.0 9.2 9 1 1 10 10 6 5 AAA domain UPF0079 PF02367.12 CCD26053.2 - 1.9e-12 46.8 5.6 0.046 13.3 0.1 6.7 7 0 0 7 7 7 3 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 CCD26053.2 - 2.4e-11 44.1 1.4 0.44 11.0 0.0 7.1 6 0 0 6 6 6 2 Miro-like protein AAA_29 PF13555.1 CCD26053.2 - 6.5e-11 41.6 0.4 0.75 9.3 0.0 6.3 6 0 0 6 6 6 3 P-loop containing region of AAA domain AAA_19 PF13245.1 CCD26053.2 - 7.9e-11 41.5 2.5 0.68 9.7 0.0 6.1 6 0 0 6 6 6 3 Part of AAA domain MobB PF03205.9 CCD26053.2 - 3.6e-10 39.6 4.2 0.56 9.9 0.0 6.6 6 0 0 6 6 6 3 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 CCD26053.2 - 2.2e-09 36.7 2.2 4 6.5 0.0 9.0 10 1 1 11 11 11 1 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 CCD26053.2 - 2.2e-09 37.2 5.7 0.58 10.1 0.1 7.3 7 0 0 7 7 6 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CCD26053.2 - 5.3e-09 35.7 1.9 0.04 13.4 0.0 6.1 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.2 CCD26053.2 - 5.9e-09 35.3 0.9 0.14 11.2 0.0 5.0 5 0 0 5 5 5 3 P-loop containing dynein motor region D3 AAA_25 PF13481.1 CCD26053.2 - 8.3e-09 35.1 2.8 0.22 10.8 0.1 5.7 6 0 0 6 6 5 2 AAA domain NACHT PF05729.7 CCD26053.2 - 4e-08 33.0 2.7 1 8.9 0.1 5.9 6 0 0 6 6 6 2 NACHT domain ABC_tran PF00005.22 CCD26053.2 - 8.5e-08 32.5 43.1 0.00094 19.4 0.0 9.0 10 0 0 10 10 6 4 ABC transporter RNA_helicase PF00910.17 CCD26053.2 - 8.8e-08 32.2 13.3 0.98 9.6 0.0 8.0 9 0 0 9 9 6 2 RNA helicase IstB_IS21 PF01695.12 CCD26053.2 - 7.2e-07 28.7 0.2 1.2 8.5 0.0 5.7 6 0 0 6 6 6 1 IstB-like ATP binding protein RuvB_N PF05496.7 CCD26053.2 - 7.4e-07 28.4 1.9 0.65 8.9 0.0 5.3 5 0 0 5 5 5 1 Holliday junction DNA helicase ruvB N-terminus ATP-synt_ab PF00006.20 CCD26053.2 - 1.2e-06 28.2 0.3 1.4 8.3 0.0 4.1 5 0 0 5 5 4 3 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.11 CCD26053.2 - 8.3e-06 25.1 2.1 2.3 7.3 0.0 5.0 5 0 0 5 5 5 1 PhoH-like protein AAA_28 PF13521.1 CCD26053.2 - 1.5e-05 25.0 9.1 1.5 8.8 0.0 6.7 6 0 0 6 6 6 1 AAA domain SRP54 PF00448.17 CCD26053.2 - 3.7e-05 23.2 7.9 0.36 10.2 0.3 5.5 5 0 0 5 5 4 2 SRP54-type protein, GTPase domain AAA_18 PF13238.1 CCD26053.2 - 0.0026 18.0 0.0 0.055 13.7 0.0 11.0 10 4 0 10 10 6 2 AAA domain FtsK_SpoIIIE PF01580.13 CCD26053.2 - 0.054 12.9 6.8 3.9 6.8 0.0 4.6 5 0 0 5 5 4 0 FtsK/SpoIIIE family tRNA_int_endo PF01974.12 CCD26054.2 - 4.2e-22 77.7 0.1 9.6e-22 76.5 0.1 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 CCD26054.2 - 0.051 13.1 0.0 0.81 9.2 0.0 2.4 2 0 0 2 2 2 0 tRNA intron endonuclease, N-terminal domain dCMP_cyt_deam_1 PF00383.17 CCD26056.2 - 2.6e-27 94.4 1.4 4.2e-27 93.7 1.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Sds3 PF08598.6 CCD26056.2 - 0.18 11.3 1.6 0.5 9.8 1.1 1.7 1 1 0 1 1 1 0 Sds3-like Hyphal_reg_CWP PF11765.3 CCD26057.2 - 0.00067 18.5 17.2 0.0055 15.4 3.9 2.6 2 1 0 3 3 3 2 Hyphally regulated cell wall protein N-terminal Nuf2 PF03800.9 CCD26059.2 - 3.1e-43 147.2 0.5 3.1e-43 147.2 0.4 2.7 3 1 0 4 4 4 1 Nuf2 family Reo_sigmaC PF04582.7 CCD26059.2 - 0.0048 16.1 5.5 0.0048 16.1 3.8 1.5 1 1 0 1 1 1 1 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 CCD26059.2 - 0.0053 16.6 15.1 0.0053 16.6 10.5 3.9 1 1 3 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GvpK PF05121.7 CCD26059.2 - 0.037 13.8 0.7 0.037 13.8 0.5 3.9 2 2 2 4 4 4 0 Gas vesicle protein K Cyclin_C PF02984.14 CCD26059.2 - 1.4 8.8 5.2 0.5 10.3 0.2 2.7 2 1 1 3 3 3 0 Cyclin, C-terminal domain AATF-Che1 PF13339.1 CCD26059.2 - 6.1 6.9 28.9 0.12 12.5 5.8 3.2 1 1 1 3 3 3 0 Apoptosis antagonizing transcription factor DUF592 PF04574.8 CCD26060.2 - 6.7e-65 217.3 4.7 1.4e-64 216.2 3.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF592) SIR2 PF02146.12 CCD26060.2 - 3.6e-61 205.9 0.0 8.6e-61 204.7 0.0 1.6 2 0 0 2 2 2 1 Sir2 family TPP_enzyme_M PF00205.17 CCD26060.2 - 0.00054 19.7 0.0 0.59 9.8 0.0 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PseudoU_synth_2 PF00849.17 CCD26061.2 - 5.1e-33 114.2 0.0 9.7e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase PQQ PF01011.16 CCD26061.2 - 0.033 13.7 0.1 0.099 12.2 0.1 1.8 1 0 0 1 1 1 0 PQQ enzyme repeat Exo_endo_phos PF03372.18 CCD26062.2 - 2.8e-12 47.0 0.0 4.1e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Baculo_PEP_C PF04513.7 CCD26062.2 - 0.04 13.7 0.2 0.31 10.8 0.1 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Inositol_P PF00459.20 CCD26063.2 - 2e-56 191.2 0.0 6.9e-56 189.5 0.0 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family DEAD PF00270.24 CCD26064.2 - 7.9e-47 158.8 0.1 7.6e-46 155.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD26064.2 - 5.8e-22 77.3 0.1 2.7e-21 75.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 CCD26064.2 - 1.3e-20 72.9 7.2 1.3e-20 72.9 5.0 3.2 3 0 0 3 3 3 1 DBP10CT (NUC160) domain SOCS PF12610.3 CCD26064.2 - 0.11 12.8 0.1 0.31 11.3 0.0 1.8 1 0 0 1 1 1 0 Suppressor of cytokine signalling DUF3449 PF11931.3 CCD26066.2 - 2.7e-64 216.3 0.7 2.7e-64 216.3 0.5 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-met PF12874.2 CCD26066.2 - 6.9e-08 32.4 7.5 1.2e-05 25.3 2.9 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCD26066.2 - 4.8e-05 23.3 10.9 5e-05 23.3 1.4 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CCD26066.2 - 0.0025 17.9 4.4 0.17 11.9 0.5 2.8 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 CCD26066.2 - 0.0049 16.3 1.3 0.015 14.8 0.9 1.9 1 0 0 1 1 1 1 U1 zinc finger Actin PF00022.14 CCD26067.2 - 3.2e-115 384.7 0.0 3.7e-115 384.4 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCD26067.2 - 0.012 14.2 0.0 0.061 11.9 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein CRT10 PF08728.5 CCD26068.2 - 5.2e-153 510.7 12.9 6.2e-153 510.4 8.9 1.1 1 0 0 1 1 1 1 CRT10 Adap_comp_sub PF00928.16 CCD26069.2 - 7.7e-75 251.3 0.3 1.3e-74 250.6 0.2 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pribosyl_synth PF14572.1 CCD26070.2 - 3.5e-41 140.9 2.9 7.4e-40 136.6 2.0 2.3 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CCD26070.2 - 1.1e-34 118.6 0.0 5.5e-34 116.3 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CCD26070.2 - 4.4e-13 49.0 0.0 1.1e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCD26070.2 - 0.095 11.8 0.1 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase DUF21 PF01595.15 CCD26071.2 - 1.4e-31 109.1 0.8 2.7e-31 108.2 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CCD26071.2 - 3.1e-05 23.6 0.0 0.12 12.1 0.0 2.8 2 0 0 2 2 2 2 CBS domain T4_Gp59_C PF08994.5 CCD26071.2 - 0.073 13.2 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term ATG2_CAD PF13329.1 CCD26072.2 - 0.095 12.2 0.1 0.17 11.4 0.1 1.5 1 1 0 1 1 1 0 Autophagy-related protein 2 CAD motif Hyphal_reg_CWP PF11765.3 CCD26073.2 - 3.8e-11 42.3 24.4 3.8e-11 42.3 16.9 1.9 2 1 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal NAD_Gly3P_dh_N PF01210.18 CCD26074.2 - 6.9e-53 178.5 0.1 6.9e-53 178.5 0.1 1.5 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CCD26074.2 - 9.3e-47 158.4 0.1 2.7e-46 156.9 0.0 1.7 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 CCD26074.2 - 0.002 18.5 0.1 0.047 14.1 0.1 2.6 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 CCD26074.2 - 0.0057 16.9 0.1 0.019 15.2 0.1 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain IlvN PF07991.7 CCD26074.2 - 0.041 13.2 0.1 0.26 10.6 0.0 2.3 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain PDH PF02153.12 CCD26074.2 - 0.082 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase Arginosuc_synth PF00764.14 CCD26075.2 - 3.1e-163 543.3 0.0 3.5e-163 543.1 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 CCD26075.2 - 0.0002 20.9 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 CCD26075.2 - 0.0008 18.7 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 CCD26075.2 - 0.012 14.1 0.0 0.019 13.5 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase His_Phos_1 PF00300.17 CCD26076.2 - 1.1e-40 139.2 0.0 2.9e-40 137.9 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-C2H2_4 PF13894.1 CCD26077.2 - 2.4e-06 27.4 1.8 0.02 15.1 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCD26077.2 - 1.6e-05 24.9 6.1 0.0061 16.8 0.2 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCD26077.2 - 0.4 11.0 4.9 2.5 8.5 0.1 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Phos_pyr_kin PF08543.7 CCD26078.2 - 6.3e-80 267.9 0.3 8.1e-80 267.5 0.2 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CCD26078.2 - 1.1e-62 211.5 0.5 1.5e-62 211.0 0.4 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 CCD26078.2 - 8.5e-06 25.1 0.0 1.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HK PF02110.10 CCD26078.2 - 0.00041 19.5 0.2 0.00077 18.6 0.1 1.4 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family UPF0158 PF03682.8 CCD26078.2 - 0.073 12.6 0.1 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) Carb_kinase PF01256.12 CCD26078.2 - 0.11 11.8 0.2 0.21 10.8 0.0 1.6 2 0 0 2 2 2 0 Carbohydrate kinase Oxysterol_BP PF01237.13 CCD26079.2 - 2.5e-129 430.8 3.2 2.5e-129 430.8 2.2 2.6 3 0 0 3 3 3 1 Oxysterol-binding protein Ank_2 PF12796.2 CCD26079.2 - 3.1e-14 53.0 0.4 1.5e-07 31.6 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCD26079.2 - 2.7e-11 43.3 0.2 0.00031 20.9 0.1 3.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCD26079.2 - 5.6e-11 41.6 0.0 0.00031 20.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CCD26079.2 - 8.6e-10 38.8 0.1 0.00033 21.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD26079.2 - 1e-08 34.5 0.0 0.0074 16.4 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat PH PF00169.24 CCD26079.2 - 1.1e-06 28.7 2.0 7.7e-06 26.0 1.4 2.7 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 CCD26079.2 - 0.0059 16.8 9.8 0.0059 16.8 6.8 4.7 4 1 0 4 4 4 1 Pleckstrin homology domain Pkinase PF00069.20 CCD26080.2 - 1.8e-70 237.0 0.1 1.8e-70 237.0 0.1 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26080.2 - 9e-53 178.9 0.0 1.7e-52 178.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD26080.2 - 6.6e-06 25.2 0.0 0.00011 21.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Actin PF00022.14 CCD26081.2 - 6.4e-161 535.1 0.0 7.2e-161 534.9 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CCD26081.2 - 0.042 14.2 0.0 0.18 12.1 0.0 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Ras PF00071.17 CCD26082.2 - 5.4e-65 217.7 0.4 6.5e-65 217.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD26082.2 - 1.5e-19 70.6 0.3 3e-19 69.6 0.1 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCD26082.2 - 2.9e-17 62.4 0.2 3.7e-17 62.1 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCD26082.2 - 1.7e-06 27.3 0.3 2.3e-06 26.9 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCD26082.2 - 7.6e-06 25.4 0.1 1.6e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCD26082.2 - 7.1e-05 22.7 0.1 0.00012 22.0 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCD26082.2 - 0.002 17.3 0.1 0.0034 16.6 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CCD26082.2 - 0.0094 16.0 0.0 0.021 14.9 0.0 1.6 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 CCD26082.2 - 0.018 14.2 0.0 0.038 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 YTH PF04146.10 CCD26082.2 - 0.032 13.8 0.2 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 YT521-B-like domain AAA_5 PF07728.9 CCD26082.2 - 0.04 13.6 0.2 0.083 12.6 0.0 1.9 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.13 CCD26082.2 - 0.042 12.8 0.2 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Septin ABC_tran PF00005.22 CCD26082.2 - 0.043 14.1 2.1 0.46 10.7 1.4 2.1 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 CCD26082.2 - 0.046 13.6 0.1 0.17 11.8 0.1 1.9 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 CCD26082.2 - 0.05 13.1 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FeoB_N PF02421.13 CCD26082.2 - 0.085 12.1 0.2 0.53 9.5 0.1 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA PF00004.24 CCD26082.2 - 0.09 12.9 0.1 0.94 9.6 0.0 2.3 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 CCD26082.2 - 4.2 5.9 6.7 11 4.5 0.2 2.7 1 1 1 2 2 2 0 G-protein alpha subunit RNA_pol PF00940.14 CCD26083.2 - 6.8e-164 545.1 0.1 1.7e-163 543.8 0.0 1.7 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CCD26083.2 - 2.6e-83 279.9 0.6 5.6e-83 278.8 0.4 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal DASH_Dad1 PF08649.5 CCD26083.2 - 0.13 11.9 6.5 0.98 9.1 0.0 4.0 3 0 0 3 3 3 0 DASH complex subunit Dad1 Mob1_phocein PF03637.12 CCD26084.2 - 3.2e-71 238.6 2.7 4.1e-71 238.2 1.9 1.1 1 0 0 1 1 1 1 Mob1/phocein family Methyltransf_12 PF08242.7 CCD26084.2 - 0.044 14.2 0.1 6.2 7.3 0.1 2.4 1 1 1 2 2 2 0 Methyltransferase domain DUF605 PF04652.11 CCD26084.2 - 6.4 6.0 15.3 8.8 5.6 10.6 1.1 1 0 0 1 1 1 0 Vta1 like Ribosomal_L22e PF01776.12 CCD26085.2 - 1.8e-41 140.6 0.6 2.6e-41 140.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF726 PF05277.7 CCD26086.2 - 7.5e-137 455.8 0.6 1.2e-136 455.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Lipase_3 PF01764.20 CCD26086.2 - 0.12 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) B3_4 PF03483.12 CCD26087.2 - 1.8e-25 89.3 0.0 3.1e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CCD26087.2 - 1.1e-17 63.6 0.1 1.8e-15 56.4 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetase B5 domain Herpes_V23 PF01802.12 CCD26087.2 - 0.0076 15.3 0.1 0.016 14.2 0.1 1.4 1 0 0 1 1 1 1 Herpesvirus VP23 like capsid protein Pkinase PF00069.20 CCD26088.2 - 2e-60 204.1 0.0 3.2e-38 131.3 0.3 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26088.2 - 2.2e-26 92.4 0.0 2e-21 76.2 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 CCD26088.2 - 1e-05 25.4 0.0 2.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 CCD26088.2 - 3.9e-05 22.7 0.0 0.0013 17.7 0.0 2.4 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CCD26088.2 - 0.00021 21.1 0.0 0.081 12.6 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CCD26088.2 - 0.0048 15.9 0.0 0.0089 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.19 CCD26088.2 - 0.029 14.1 0.0 0.1 12.3 0.0 1.9 1 0 0 1 1 1 0 PAS fold Tricorn_C1 PF14684.1 CCD26088.2 - 0.19 11.6 0.2 0.59 10.0 0.1 1.8 1 0 0 1 1 1 0 Tricorn protease C1 domain bZIP_1 PF00170.16 CCD26089.2 - 0.00011 22.0 6.1 0.00024 20.9 4.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCD26089.2 - 0.00025 20.7 8.0 0.00025 20.7 5.6 1.8 1 1 0 1 1 1 1 Basic region leucine zipper Aminotran_5 PF00266.14 CCD26090.2 - 7.9e-22 77.5 0.0 1e-21 77.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V SHMT PF00464.14 CCD26091.2 - 1.5e-206 685.4 0.0 1.7e-206 685.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 CCD26091.2 - 3.4e-07 29.5 0.0 9.8e-07 28.0 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCD26091.2 - 2.3e-05 23.3 0.0 3.4e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCD26091.2 - 0.0004 19.6 0.0 0.00071 18.8 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Pkinase PF00069.20 CCD26092.2 - 4.9e-25 88.1 0.5 3.4e-24 85.4 0.2 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26092.2 - 2.1e-14 53.2 0.0 3.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD26092.2 - 0.011 14.7 0.0 0.027 13.4 0.0 1.6 2 0 0 2 2 2 0 Kinase-like YrbL-PhoP_reg PF10707.4 CCD26092.2 - 0.014 14.7 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 CCD26092.2 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD26092.2 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ABC_tran PF00005.22 CCD26093.2 - 1e-18 67.9 0.0 1.9e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCD26093.2 - 3.5e-10 40.3 1.4 4.2e-08 33.4 1.0 2.3 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 CCD26093.2 - 1.7e-06 27.4 0.0 0.013 14.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CCD26093.2 - 3.9e-06 26.1 0.0 0.023 13.7 0.0 2.1 1 1 1 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 CCD26093.2 - 0.00026 20.4 0.0 0.00055 19.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 CCD26093.2 - 0.00053 19.5 0.0 0.00085 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain AAA_23 PF13476.1 CCD26093.2 - 0.0016 18.8 0.1 0.0029 17.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCD26093.2 - 0.0022 18.7 0.3 0.0064 17.3 0.2 2.0 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 CCD26093.2 - 0.0028 16.8 0.0 0.0044 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCD26093.2 - 0.0084 16.4 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 CCD26093.2 - 0.017 14.9 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Dynamin family MutS_V PF00488.16 CCD26093.2 - 0.019 14.3 0.0 3.3 7.0 0.0 2.3 2 0 0 2 2 2 0 MutS domain V FtsK_SpoIIIE PF01580.13 CCD26093.2 - 0.029 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3584 PF12128.3 CCD26093.2 - 0.055 10.8 0.1 0.072 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA PF00004.24 CCD26093.2 - 0.059 13.5 0.3 1.7 8.8 0.1 2.6 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 CCD26093.2 - 0.062 12.7 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_24 PF13479.1 CCD26093.2 - 0.071 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 CCD26093.2 - 0.083 12.3 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 CCD26093.2 - 0.084 12.7 0.0 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CCD26093.2 - 0.13 11.3 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 CCD26093.2 - 0.13 12.2 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RabGAP-TBC PF00566.13 CCD26094.2 - 5.4e-16 58.7 11.2 2.3e-15 56.6 7.8 2.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain STE2 PF02116.10 CCD26095.2 - 2.7e-105 351.4 22.4 3.2e-105 351.2 15.6 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF2976 PF11190.3 CCD26095.2 - 0.14 11.6 8.3 0.15 11.5 2.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) PGAP1 PF07819.8 CCD26096.2 - 3.4e-88 295.0 0.0 5.5e-88 294.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CCD26096.2 - 0.00082 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD26096.2 - 0.0033 17.0 0.0 0.0053 16.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCD26096.2 - 0.0059 16.3 0.0 0.016 15.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family EPL1 PF10513.4 CCD26097.2 - 1.1e-33 116.7 4.0 1.1e-33 116.7 2.7 3.7 4 1 0 4 4 4 1 Enhancer of polycomb-like Prefoldin PF02996.12 CCD26098.2 - 7e-13 48.2 0.5 7e-13 48.2 0.3 3.4 3 0 0 3 3 3 1 Prefoldin subunit DUF3835 PF12927.2 CCD26098.2 - 1.6e-12 48.1 0.3 1.6e-12 48.1 0.2 7.9 7 2 2 9 9 9 2 Domain of unknown function (DUF3835) GCR1_C PF12550.3 CCD26099.2 - 1e-10 41.3 1.3 2.8e-09 36.7 0.6 2.4 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes UCH PF00443.24 CCD26099.2 - 0.35 9.9 2.7 0.4 9.7 1.8 1.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase tRNA-synt_2d PF01409.15 CCD26100.2 - 1.5e-91 305.9 0.0 2e-91 305.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 CCD26100.2 - 1.3e-06 28.1 0.1 2.4e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 CCD26100.2 - 3.6e-05 22.7 2.0 0.00031 19.6 0.0 3.0 3 1 1 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_His PF13393.1 CCD26100.2 - 0.0003 19.9 0.1 0.0075 15.3 0.0 2.2 2 0 0 2 2 2 1 Histidyl-tRNA synthetase GATA PF00320.22 CCD26102.2 - 6.8e-16 57.3 3.9 1.4e-15 56.2 2.7 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 CCD26102.2 - 5e-08 32.3 0.2 1.1e-07 31.3 0.1 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 CCD26102.2 - 0.21 10.9 2.4 0.53 9.6 1.4 1.9 1 1 0 1 1 1 0 TFIIB zinc-binding DNA_RNApol_7kD PF03604.8 CCD26102.2 - 0.47 9.9 2.3 0.4 10.2 0.1 2.0 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit LSM PF01423.17 CCD26103.2 - 3.8e-16 58.3 0.1 4.2e-16 58.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain Acetyltransf_1 PF00583.19 CCD26104.2 - 3.1e-15 55.9 0.0 5.3e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCD26104.2 - 4e-10 39.7 0.0 5.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCD26104.2 - 6.9e-05 22.9 0.0 8.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCD26104.2 - 0.00022 21.0 0.0 0.0005 19.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCD26104.2 - 0.0058 16.7 0.0 0.0074 16.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCD26104.2 - 0.02 14.8 0.1 0.022 14.7 0.1 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DnaJ PF00226.26 CCD26105.2 - 3.3e-25 87.5 4.8 7e-25 86.5 3.3 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCD26105.2 - 2.1e-21 75.6 3.5 9.4e-16 57.4 0.4 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCD26105.2 - 1.1e-13 50.9 16.8 2e-13 50.1 11.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CCD26105.2 - 0.0017 18.0 6.8 0.035 13.8 0.6 2.3 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 CCD26105.2 - 0.1 12.9 13.4 0.43 10.9 9.1 2.2 1 1 1 2 2 2 0 Cytochrome c3 Antiterm PF03589.8 CCD26105.2 - 5.2 7.2 9.8 40 4.3 0.2 3.9 2 1 2 4 4 4 0 Antitermination protein HSP9_HSP12 PF04119.7 CCD26106.2 - 4.1e-28 97.2 6.4 1.2e-27 95.7 1.0 2.1 2 0 0 2 2 2 2 Heat shock protein 9/12 ApoA-II PF04711.8 CCD26106.2 - 0.078 12.8 1.0 0.23 11.3 0.1 1.9 1 1 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) YtxH PF12732.2 CCD26106.2 - 0.12 12.7 5.9 4.8 7.6 4.1 2.2 1 1 0 1 1 1 0 YtxH-like protein WD40 PF00400.27 CCD26108.2 - 3e-48 160.0 12.2 4.2e-10 39.1 0.7 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 CCD26108.2 - 1.9e-10 40.2 0.5 4.4e-10 39.1 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCD26108.2 - 1.5e-07 30.9 1.6 1.8e-07 30.5 0.2 1.8 2 0 0 2 2 2 1 F-box domain SMC_N PF02463.14 CCD26109.2 - 4.7e-52 176.3 65.0 2.2e-51 174.1 45.1 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCD26109.2 - 1.4e-25 89.5 0.0 2.3e-24 85.6 0.0 3.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCD26109.2 - 2.9e-10 40.6 22.2 1.4e-06 28.5 3.5 5.8 2 2 2 4 4 3 2 AAA domain AAA_23 PF13476.1 CCD26109.2 - 1.3e-08 35.4 51.0 1.3e-08 35.4 35.4 7.0 3 2 1 4 4 2 1 AAA domain AAA_29 PF13555.1 CCD26109.2 - 3.1e-08 33.0 0.1 6.6e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Myosin_tail_1 PF01576.14 CCD26109.2 - 4.4e-05 21.4 42.1 4.4e-05 21.4 29.2 4.1 3 1 0 4 4 4 2 Myosin tail WEMBL PF05701.6 CCD26109.2 - 0.00022 19.8 37.5 0.00022 19.8 26.0 4.6 3 1 0 3 3 2 2 Weak chloroplast movement under blue light HisKA_3 PF07730.8 CCD26109.2 - 0.025 14.9 9.5 8 6.8 0.4 5.2 4 1 0 4 4 3 0 Histidine kinase HrpB7 PF09486.5 CCD26109.2 - 0.2 11.5 33.6 1.3 8.9 5.9 6.8 4 2 2 7 7 7 0 Bacterial type III secretion protein (HrpB7) FUSC PF04632.7 CCD26109.2 - 0.44 8.9 3.2 0.44 8.9 0.4 2.0 2 0 0 2 2 2 0 Fusaric acid resistance protein family Reo_sigmaC PF04582.7 CCD26109.2 - 1.5 7.9 37.7 0.18 10.9 3.4 4.6 3 1 0 4 4 4 0 Reovirus sigma C capsid protein DASH_Dam1 PF08653.5 CCD26109.2 - 5.1 6.9 10.0 2.3 8.0 0.1 4.9 4 0 0 4 4 4 0 DASH complex subunit Dam1 DUF3437 PF11919.3 CCD26110.2 - 1.9e-28 97.9 0.0 6.3e-28 96.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Ras PF00071.17 CCD26111.2 - 1.2e-63 213.3 0.4 1.4e-63 213.1 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD26111.2 - 9.5e-20 71.2 0.1 1.4e-19 70.7 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCD26111.2 - 2.8e-19 69.0 0.2 3.2e-19 68.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCD26111.2 - 1.9e-07 30.4 0.1 2.2e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCD26111.2 - 2.2e-07 30.2 0.2 2.8e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CCD26111.2 - 4.6e-06 26.1 0.1 7.9e-05 22.1 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCD26111.2 - 8.6e-06 25.6 0.1 1.4e-05 24.9 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CCD26111.2 - 0.0044 17.1 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 CCD26111.2 - 0.0061 15.8 0.2 0.1 11.8 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 CCD26111.2 - 0.012 15.6 0.2 0.028 14.3 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CCD26111.2 - 0.014 14.5 0.0 0.024 13.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCD26111.2 - 0.016 14.6 0.2 0.073 12.6 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.18 CCD26111.2 - 0.062 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family DUF815 PF05673.8 CCD26111.2 - 0.088 11.7 0.1 0.19 10.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.24 CCD26111.2 - 0.094 12.9 0.1 0.61 10.2 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 CCD26111.2 - 0.13 10.8 1.3 1.9 7.0 0.1 2.5 1 1 1 2 2 2 0 G-protein alpha subunit VTC PF09359.5 CCD26112.2 - 1.6e-94 316.0 0.6 1.6e-94 316.0 0.4 1.7 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 CCD26112.2 - 4.6e-27 95.4 25.2 9.7e-17 61.6 6.6 4.3 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.10 CCD26112.2 - 3.4e-09 36.7 0.6 3.4e-09 36.7 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) MutS_V PF00488.16 CCD26113.2 - 2.5e-63 213.6 0.0 5.6e-63 212.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCD26113.2 - 1.2e-27 97.0 2.8 1.2e-27 97.0 1.9 1.8 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 CCD26113.2 - 9.6e-13 48.3 0.3 2.6e-12 46.9 0.2 1.7 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CCD26113.2 - 5.4e-10 39.3 0.1 5.4e-10 39.3 0.1 2.8 3 0 0 3 3 3 1 MutS family domain IV rve PF00665.21 CCD26114.2 - 2e-19 69.8 0.0 5.9e-19 68.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CCD26114.2 - 3.6e-12 46.1 1.2 8.5e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 CCD26115.2 - 1.3e-05 25.0 0.1 4.9e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CCD26115.2 - 0.00018 21.2 0.0 0.00033 20.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 CCD26115.2 - 0.0029 18.0 0.0 0.0071 16.8 0.0 1.8 1 1 0 1 1 1 1 Aspartyl protease Peptidase_A2B PF12384.3 CCD26115.2 - 0.01 15.1 0.1 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase Asp_protease PF09668.5 CCD26115.2 - 0.044 13.3 0.0 0.095 12.2 0.0 1.5 1 1 0 1 1 1 0 Aspartyl protease Ph1570 PF09638.5 CCD26115.2 - 0.12 12.1 0.0 0.19 11.5 0.0 1.2 1 0 0 1 1 1 0 Ph1570 protein DUF3441 PF11923.3 CCD26117.2 - 8.6e-34 115.5 0.9 8.6e-34 115.5 0.6 3.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3441) FbpA PF05833.6 CCD26117.2 - 6.7e-26 90.8 37.7 6.7e-26 90.8 26.1 3.7 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 CCD26117.2 - 1.3e-11 44.2 0.3 4.6e-11 42.4 0.2 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF814) 2-Hacid_dh_C PF02826.14 CCD26118.2 - 2.3e-30 105.0 0.0 5.4e-30 103.8 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCD26118.2 - 4e-09 36.0 0.0 1.5e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ApbA PF02558.11 CCD26118.2 - 0.019 14.4 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 CCD26118.2 - 0.037 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 CCD26118.2 - 0.076 12.8 0.1 8.3 6.2 0.0 2.4 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain zf-C2H2 PF00096.21 CCD26119.2 - 1.4e-11 43.9 12.9 6.4e-06 26.1 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD26119.2 - 2.5e-09 36.7 11.9 0.00035 20.6 1.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD26119.2 - 1.1e-07 31.7 13.7 1.5e-05 25.0 2.6 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCD26119.2 - 5.6e-07 29.5 5.0 0.011 15.8 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCD26119.2 - 2.3e-05 24.3 9.5 0.0047 17.0 0.8 3.0 3 0 0 3 3 2 2 Zinc-finger of C2H2 type zf-BED PF02892.10 CCD26119.2 - 0.00033 20.3 3.7 0.35 10.6 0.5 2.8 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.1 CCD26119.2 - 0.00068 19.4 5.6 0.012 15.4 0.2 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-Di19 PF05605.7 CCD26119.2 - 0.011 15.8 2.8 0.025 14.6 1.9 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CCD26119.2 - 0.021 14.9 5.8 0.95 9.6 0.3 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.7 CCD26119.2 - 0.3 9.5 5.9 0.65 8.4 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF629) DUF2225 PF09986.4 CCD26119.2 - 0.42 10.0 4.2 5 6.5 0.2 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) GAGA PF09237.6 CCD26119.2 - 0.94 9.1 8.0 0.62 9.6 0.0 2.5 1 1 1 2 2 2 0 GAGA factor DUF1642 PF07852.6 CCD26119.2 - 4.8 7.5 0.0 4.8 7.5 0.0 4.5 4 1 1 5 5 5 0 Protein of unknown function (DUF1642) Mnd1 PF03962.10 CCD26120.2 - 8.9e-39 133.0 8.4 1.1e-38 132.8 5.8 1.1 1 0 0 1 1 1 1 Mnd1 family ArfGap PF01412.13 CCD26121.2 - 3.2e-30 104.3 1.5 3.6e-30 104.1 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.26 CCD26121.2 - 0.019 14.7 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain Blt1 PF12754.2 CCD26121.2 - 0.04 13.5 6.9 0.76 9.3 4.8 2.2 1 1 1 2 2 2 0 Cell-cycle control medial ring component HTH_34 PF13601.1 CCD26121.2 - 0.13 12.3 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Winged helix DNA-binding domain PAT1 PF09770.4 CCD26121.2 - 0.3 9.2 24.4 0.35 9.0 16.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 CCD26121.2 - 0.34 9.0 43.1 0.41 8.7 29.9 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF3543 PF12063.3 CCD26122.2 - 1.6e-67 227.1 10.1 1.6e-67 227.1 7.0 2.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 CCD26122.2 - 1.2e-59 201.6 1.1 2.5e-59 200.5 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26122.2 - 4e-43 147.3 0.0 7.8e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCD26122.2 - 0.096 12.4 0.2 0.27 10.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family SRP1_TIP1 PF00660.12 CCD26123.2 - 1.7e-18 66.3 0.0 1.9e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family Pkinase PF00069.20 CCD26124.2 - 2.7e-59 200.4 0.0 4.4e-59 199.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26124.2 - 2.5e-28 98.8 0.0 4.2e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD26124.2 - 7.7e-07 28.3 0.0 2.9e-06 26.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCD26124.2 - 0.034 13.8 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PUF PF00806.14 CCD26125.2 - 9e-55 179.1 27.5 8.9e-08 31.2 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Bud13 PF09736.4 CCD26128.2 - 4.2e-25 88.7 9.2 4.2e-25 88.7 6.3 3.0 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DUF3492 PF11997.3 CCD26128.2 - 0.79 9.2 6.9 0.16 11.4 1.6 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) XRN_N PF03159.13 CCD26129.2 - 5.6e-101 336.8 0.1 1.1e-100 335.8 0.1 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Nucleoporin_FG PF13634.1 CCD26130.2 - 2.9e-35 120.9 156.0 1.4e-12 47.8 34.3 4.6 2 1 3 5 5 5 4 Nucleoporin FG repeat region DUF1664 PF07889.7 CCD26130.2 - 0.069 12.9 3.5 0.29 10.9 1.4 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ATP-synt_G PF04718.10 CCD26131.2 - 7.4e-28 97.2 0.8 9.2e-28 96.9 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit MCM PF00493.18 CCD26132.2 - 2.9e-138 460.1 0.0 4e-138 459.7 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCD26132.2 - 3.7e-23 82.2 7.4 9.5e-23 80.9 3.4 3.0 3 1 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 CCD26132.2 - 1.5e-05 24.7 0.0 8.3e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCD26132.2 - 1.6e-05 24.1 0.0 0.00064 18.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCD26132.2 - 0.0016 18.0 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCD26132.2 - 0.13 11.7 1.2 4 6.8 0.0 3.3 4 0 0 4 4 4 0 Sigma-54 interaction domain CAF1A PF12253.3 CCD26133.2 - 5.3e-23 80.9 9.7 5.3e-23 80.9 6.7 3.5 3 0 0 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 CCD26133.2 - 1.2e-13 50.9 54.2 1.2e-13 50.9 37.5 2.8 3 0 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2508 PF10704.4 CCD26134.2 - 0.053 13.6 0.6 0.29 11.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) Mak16 PF04874.9 CCD26134.2 - 0.16 12.0 2.4 11 6.2 0.0 3.0 3 0 0 3 3 3 0 Mak16 protein C-terminal region rve PF00665.21 CCD26136.2 - 2.2e-18 66.5 0.0 3.3e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CCD26136.2 - 0.064 12.7 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain RNA_pol_Rpb2_6 PF00562.23 CCD26137.2 - 5.1e-114 381.0 0.0 7.2e-114 380.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCD26137.2 - 1.3e-49 167.8 0.1 1.9e-49 167.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCD26137.2 - 3e-37 127.8 0.0 6.7e-37 126.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 CCD26137.2 - 1.6e-24 85.4 0.0 8.7e-24 83.0 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 CCD26137.2 - 5.3e-23 80.7 0.0 1.1e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 CCD26137.2 - 1.6e-15 57.1 0.0 1.1e-14 54.4 0.0 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 CCD26137.2 - 1.5e-06 28.0 0.3 3.3e-06 26.9 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 E1-E2_ATPase PF00122.15 CCD26138.2 - 5.9e-78 261.0 0.1 1.3e-77 259.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCD26138.2 - 2.8e-47 160.6 1.8 2.8e-47 160.6 1.3 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCD26138.2 - 1.7e-31 110.3 0.1 3e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCD26138.2 - 7.4e-21 73.9 0.0 1.5e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCD26138.2 - 2.1e-16 60.6 0.0 4.3e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCD26138.2 - 2.1e-16 59.0 0.0 5.9e-16 57.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCD26138.2 - 8.3e-06 25.5 1.0 0.00056 19.5 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sua5_yciO_yrdC PF01300.13 CCD26139.2 - 2.9e-48 163.4 0.0 6.4e-48 162.3 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 CCD26139.2 - 1.7e-27 95.9 0.0 2.7e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Zn_clus PF00172.13 CCD26143.2 - 0.0089 15.9 3.9 0.0089 15.9 2.7 2.8 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DCP1 PF06058.8 CCD26144.2 - 3.2e-16 59.4 1.7 6e-09 35.9 0.0 3.1 2 1 1 3 3 3 2 Dcp1-like decapping family Spt20 PF12090.3 CCD26146.2 - 4.7e-52 175.9 23.3 4.7e-52 175.9 16.1 4.7 4 2 0 4 4 4 1 Spt20 family PEX11 PF05648.9 CCD26147.2 - 9.4e-60 201.6 1.8 1.1e-59 201.4 1.3 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) TPR_11 PF13414.1 CCD26148.2 - 1.5e-26 91.8 22.0 1.6e-05 24.4 0.0 10.7 8 3 3 12 12 12 8 TPR repeat TPR_2 PF07719.12 CCD26148.2 - 7.7e-24 81.6 29.9 0.00016 21.3 0.0 13.4 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCD26148.2 - 1.2e-22 80.0 11.1 8e-06 26.1 0.0 9.8 8 3 2 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 CCD26148.2 - 1.3e-22 79.4 13.7 0.0097 15.8 0.1 10.8 8 5 2 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 CCD26148.2 - 2.4e-21 74.3 47.8 7.7e-06 25.2 0.0 12.9 15 0 0 15 15 14 8 Tetratricopeptide repeat TPR_16 PF13432.1 CCD26148.2 - 3.2e-18 65.8 0.0 0.003 18.1 0.0 8.4 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCD26148.2 - 7.2e-17 60.3 0.0 0.037 14.6 0.0 10.9 11 1 2 13 13 10 2 Tetratricopeptide repeat Apc3 PF12895.2 CCD26148.2 - 4.9e-14 52.2 18.5 0.01 15.9 0.0 8.9 5 4 5 10 10 10 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCD26148.2 - 8.4e-12 43.9 52.4 0.00047 19.7 0.2 12.9 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_7 PF13176.1 CCD26148.2 - 1.2e-10 40.3 11.4 0.73 9.7 0.0 10.1 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCD26148.2 - 3.8e-10 39.5 20.7 0.87 10.1 0.0 11.5 13 1 0 13 13 11 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCD26148.2 - 1.7e-05 24.5 16.1 3 8.2 0.0 10.8 14 1 0 14 14 14 1 Tetratricopeptide repeat TPR_10 PF13374.1 CCD26148.2 - 0.17 11.8 17.9 3.6 7.6 0.1 8.1 10 0 0 10 10 8 0 Tetratricopeptide repeat RRM_5 PF13893.1 CCD26149.2 - 1.5e-06 27.9 0.1 3.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DMRL_synthase PF00885.14 CCD26150.2 - 2e-45 154.0 0.0 2.4e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Hist_deacetyl PF00850.14 CCD26151.2 - 1.7e-81 273.8 0.0 2.6e-81 273.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain UBA_e1_C PF09358.5 CCD26152.2 - 0.051 13.7 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain LCM PF04072.9 CCD26153.2 - 1.2e-23 83.6 0.0 1.8e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_5 PF13854.1 CCD26153.2 - 0.00011 22.0 0.2 0.0032 17.3 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 CCD26153.2 - 0.0034 17.1 0.8 3.4 7.4 0.0 4.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CCD26153.2 - 0.0047 17.0 4.4 0.076 13.2 0.0 3.9 6 0 0 6 6 6 1 Kelch motif Kelch_3 PF13415.1 CCD26153.2 - 0.0091 16.1 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.20 CCD26153.2 - 0.04 13.4 0.6 0.81 9.2 0.0 3.0 4 0 0 4 4 4 0 Kelch motif CDC50 PF03381.10 CCD26154.2 - 1.9e-88 296.2 0.3 2.8e-88 295.6 0.2 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Aminotran_3 PF00202.16 CCD26155.2 - 3.8e-110 367.9 0.1 4.6e-110 367.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III PucR PF07905.6 CCD26155.2 - 0.0027 17.2 0.0 0.067 12.7 0.0 2.7 3 0 0 3 3 3 1 Purine catabolism regulatory protein-like family IF4E PF01652.13 CCD26156.2 - 1.1e-57 194.1 0.8 1.3e-57 193.8 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Abhydrolase_5 PF12695.2 CCD26157.2 - 4.2e-17 62.2 0.0 5.5e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD26157.2 - 3.4e-11 43.1 0.0 0.0002 21.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCD26157.2 - 3.5e-11 43.4 0.0 2.6e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCD26157.2 - 2.9e-06 26.6 0.0 1.3e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 CCD26157.2 - 1.8e-05 24.5 0.0 0.0051 16.5 0.0 2.4 2 1 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 CCD26157.2 - 0.00017 21.0 0.0 0.00027 20.4 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.7 CCD26157.2 - 0.0002 20.2 0.2 0.00025 19.9 0.1 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) PAF-AH_p_II PF03403.8 CCD26157.2 - 0.0052 15.1 0.0 0.0073 14.6 0.0 1.2 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S15 PF02129.13 CCD26157.2 - 0.0068 15.8 0.0 0.04 13.3 0.0 1.9 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1749 PF08538.5 CCD26157.2 - 0.0071 15.2 0.1 0.02 13.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Abhydrolase_2 PF02230.11 CCD26157.2 - 0.01 15.2 0.0 1.3 8.3 0.0 2.2 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase AXE1 PF05448.7 CCD26157.2 - 0.021 13.3 0.0 4.8 5.5 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 CCD26157.2 - 0.026 13.8 0.0 0.18 11.0 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family WD40 PF00400.27 CCD26158.2 - 2.6e-13 49.2 9.4 5.8e-08 32.3 0.1 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-RING_2 PF13639.1 CCD26158.2 - 3.6e-05 23.4 7.5 0.0001 22.0 5.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCD26158.2 - 6.7e-05 22.9 5.1 0.00024 21.1 3.5 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CCD26158.2 - 0.00044 19.8 4.1 0.0016 18.0 2.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD26158.2 - 0.001 19.0 7.6 0.001 19.0 5.3 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCD26158.2 - 2.6 7.9 7.9 6.8 6.6 5.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 CCD26158.2 - 5.8 7.0 10.3 15 5.6 7.2 1.8 1 0 0 1 1 1 0 RING-like domain MFS_1 PF07690.11 CCD26159.2 - 2.2e-30 105.5 34.8 5.3e-25 87.8 8.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 CCD26160.2 - 8.5e-44 145.9 13.9 5.3e-10 38.7 0.3 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CCD26160.2 - 1.5e-05 24.7 9.4 0.01 15.5 0.1 3.6 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 CCD26160.2 - 0.064 12.7 0.0 13 5.3 0.0 2.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain 6PF2K PF01591.13 CCD26161.2 - 1.3e-46 158.4 3.5 3e-46 157.2 2.4 1.6 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_17 PF13207.1 CCD26161.2 - 0.00016 22.4 0.0 0.00046 21.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCD26161.2 - 0.0011 18.9 0.0 0.0025 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCD26161.2 - 0.0027 16.9 0.6 0.023 13.9 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 CCD26161.2 - 0.034 14.4 0.1 0.16 12.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain Ten1 PF12658.2 CCD26161.2 - 0.063 13.0 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 Telomere capping, CST complex subunit Med7 PF05983.6 CCD26162.2 - 1.7e-35 122.2 1.1 2.1e-35 121.8 0.8 1.0 1 0 0 1 1 1 1 MED7 protein zf-rbx1 PF12678.2 CCD26163.2 - 6.1e-32 109.5 13.9 8e-32 109.1 9.6 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCD26163.2 - 4.8e-17 61.5 10.2 6.4e-17 61.1 7.1 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CCD26163.2 - 3e-07 30.1 11.9 2.3e-06 27.3 8.2 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCD26163.2 - 0.0026 17.3 11.7 0.026 14.1 8.1 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD26163.2 - 0.018 15.0 1.9 0.018 15.0 1.3 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CCD26163.2 - 0.054 13.0 2.7 0.1 12.1 1.9 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 CCD26163.2 - 0.088 12.5 10.1 3.8 7.2 7.0 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCD26163.2 - 0.089 12.5 6.1 0.24 11.1 3.1 2.5 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCD26163.2 - 0.39 10.6 7.2 0.35 10.7 0.3 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCD26163.2 - 0.78 9.5 10.5 5.8 6.7 7.3 2.3 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 CCD26163.2 - 1.9 8.5 9.9 11 6.0 7.0 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 CCD26163.2 - 3.1 8.0 10.1 1.8e+02 2.3 7.0 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain TPR_11 PF13414.1 CCD26164.2 - 2e-16 59.3 1.7 5.5e-11 41.9 0.3 4.0 3 0 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 CCD26164.2 - 7.2e-08 32.4 0.0 0.18 12.5 0.1 5.1 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCD26164.2 - 9.9e-08 32.2 0.2 0.0059 16.9 0.0 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCD26164.2 - 1.3e-07 30.9 7.3 0.0065 16.2 0.2 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCD26164.2 - 5e-07 29.5 0.0 0.0029 17.4 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCD26164.2 - 1.9e-06 28.3 0.1 3.2 8.5 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCD26164.2 - 9.1e-05 22.3 0.4 0.033 14.3 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCD26164.2 - 0.00014 21.3 4.6 0.58 9.8 0.2 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCD26164.2 - 0.00025 20.6 5.9 1.5 8.8 0.0 5.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCD26164.2 - 0.0026 17.4 2.0 1.1 9.2 0.1 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 CCD26164.2 - 0.0092 16.0 1.9 0.85 9.7 1.1 3.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 CCD26164.2 - 0.027 13.8 3.9 1.5 8.1 0.1 3.4 3 1 0 3 3 3 0 26S proteasome subunit RPN7 tRNA_anti-codon PF01336.20 CCD26165.2 - 1.6e-10 40.7 0.1 3.1e-10 39.7 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 CCD26165.2 - 7.8e-07 29.4 0.1 2.3e-06 27.9 0.0 1.9 2 0 0 2 2 2 1 Replication protein A C terminal HTH_IclR PF09339.5 CCD26165.2 - 0.047 13.2 0.0 0.079 12.5 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain tRNA_anti_2 PF13742.1 CCD26165.2 - 0.055 13.3 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain DUF4539 PF15072.1 CCD26165.2 - 0.13 11.9 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4539) Glyco_hydro_72 PF03198.9 CCD26166.2 - 2.8e-132 440.4 1.2 3.5e-132 440.1 0.8 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_cc PF11790.3 CCD26166.2 - 0.0012 18.3 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core UPF0220 PF05255.6 CCD26168.2 - 4.9e-69 230.8 1.9 5.5e-69 230.6 1.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Pkinase PF00069.20 CCD26169.2 - 1.5e-57 194.7 0.0 1.8e-57 194.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26169.2 - 5.5e-30 104.3 0.0 7.1e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD26169.2 - 4.4e-06 25.8 0.0 6.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCD26169.2 - 0.00049 19.8 0.0 0.0008 19.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCD26169.2 - 0.01 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CCD26169.2 - 0.011 15.2 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L23 PF00276.15 CCD26170.2 - 7.9e-18 64.1 1.3 9.5e-18 63.9 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 Lipoprotein_1 PF00820.14 CCD26170.2 - 0.017 14.1 0.2 0.02 13.9 0.2 1.0 1 0 0 1 1 1 0 Borrelia lipoprotein Levi_coat PF01819.12 CCD26170.2 - 0.033 13.7 0.1 0.039 13.5 0.1 1.1 1 0 0 1 1 1 0 Levivirus coat protein Ldh_1_C PF02866.13 CCD26171.2 - 6.1e-43 146.5 0.0 9.1e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CCD26171.2 - 4.7e-41 139.9 0.1 7.2e-41 139.3 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 CCD26171.2 - 0.14 12.4 0.0 0.74 10.1 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TRM13 PF05206.9 CCD26172.2 - 1.9e-77 260.0 0.8 1.9e-77 260.0 0.5 1.6 2 0 0 2 2 2 1 Methyltransferase TRM13 zf-U11-48K PF05253.7 CCD26172.2 - 1.2e-10 40.8 3.0 1.2e-10 40.8 2.1 2.2 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger zf-TRM13_CCCH PF11722.3 CCD26172.2 - 2.5e-08 33.1 2.3 2.5e-08 33.1 1.6 2.3 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein UPF0020 PF01170.13 CCD26173.2 - 1.5e-12 47.5 0.0 2.7e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CCD26173.2 - 7.4e-08 32.4 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CCD26173.2 - 0.0059 16.1 0.9 0.24 10.8 0.4 2.6 2 1 0 2 2 2 1 DNA methylase RRM_1 PF00076.17 CCD26174.2 - 2.6e-35 119.8 1.0 1.3e-17 63.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD26174.2 - 1.8e-32 111.0 0.1 5e-16 58.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD26174.2 - 6.5e-15 54.7 0.2 4e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nramp PF01566.13 CCD26175.2 - 2.7e-90 302.7 13.2 2.7e-90 302.7 9.2 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Ribosomal_S19e PF01090.14 CCD26176.2 - 7.7e-55 184.1 0.1 8.5e-55 184.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L18e PF00828.14 CCD26177.2 - 8.6e-26 90.8 0.1 1.3e-25 90.2 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 GCR1_C PF12550.3 CCD26179.2 - 5e-23 80.7 0.1 1.1e-22 79.6 0.1 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes NTP_transf_2 PF01909.18 CCD26180.2 - 2.8e-15 56.4 0.1 8.4e-15 54.8 0.1 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CCD26180.2 - 7.2e-13 48.2 0.0 1.8e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase RF-1 PF00472.15 CCD26181.2 - 3.2e-13 49.4 0.0 4.4e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 RF-1 domain MRP-S28 PF10213.4 CCD26181.2 - 0.00078 19.5 0.3 0.0013 18.8 0.2 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit protein RabGAP-TBC PF00566.13 CCD26182.2 - 3.9e-43 147.4 6.2 2.9e-42 144.5 4.3 2.2 1 1 0 1 1 1 1 Rab-GTPase-TBC domain ubiquitin PF00240.18 CCD26183.2 - 0.00045 19.5 0.1 0.00098 18.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Homeobox PF00046.24 CCD26184.1 - 1.7e-13 49.9 0.9 2.9e-13 49.2 0.7 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCD26184.1 - 0.00023 20.7 0.1 0.00044 19.8 0.1 1.7 1 1 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 CCD26184.1 - 0.014 14.3 0.2 0.026 13.5 0.1 1.6 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Sir1 PF11603.3 CCD26185.1 - 5e-13 49.3 0.0 1.9e-11 44.1 0.0 2.6 2 0 0 2 2 2 1 Regulatory protein Sir1 Reg_prop PF07494.6 CCD26185.1 - 0.14 12.2 0.4 0.62 10.2 0.1 2.3 2 0 0 2 2 2 0 Two component regulator propeller DHO_dh PF01180.16 CCD26186.1 - 4.5e-92 308.1 0.0 5e-92 307.9 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CCD26186.1 - 7.2e-05 21.7 0.0 0.0045 15.8 0.0 2.2 2 0 0 2 2 2 2 FMN-dependent dehydrogenase DUF885 PF05960.6 CCD26186.1 - 0.064 12.3 0.0 0.085 12.0 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Polysacc_deac_1 PF01522.16 CCD26186.1 - 0.11 12.0 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide deacetylase SBF PF01758.11 CCD26187.1 - 3.7e-49 166.6 15.9 3.7e-49 166.6 11.0 1.9 2 0 0 2 2 2 1 Sodium Bile acid symporter family Myc_target_1 PF15179.1 CCD26187.1 - 0.075 12.6 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 Myc target protein 1 DUF3464 PF11947.3 CCD26187.1 - 1.7 8.0 3.5 0.57 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) MFS_1 PF07690.11 CCD26188.1 - 8.8e-11 41.1 42.1 4.8e-10 38.6 28.6 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CCD26188.1 - 1.1e-05 23.9 24.1 0.00046 18.5 16.7 2.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCD26188.1 - 2.9 6.3 30.2 0.074 11.6 9.3 2.5 2 1 0 2 2 2 0 Sugar (and other) transporter SET PF00856.23 CCD26189.1 - 1.1e-05 25.7 0.3 7.3e-05 23.1 0.2 2.3 2 0 0 2 2 2 1 SET domain RTTN_N PF14726.1 CCD26189.1 - 0.1 13.2 2.3 15 6.2 0.0 2.7 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Cofilin_ADF PF00241.15 CCD26190.1 - 1.4e-45 154.2 0.8 1.5e-45 154.1 0.5 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CBM_4_9 PF02018.12 CCD26190.1 - 0.011 15.7 0.1 0.024 14.6 0.0 1.5 2 0 0 2 2 2 0 Carbohydrate binding domain AA_permease_2 PF13520.1 CCD26192.1 - 1.2e-50 172.3 40.1 1.5e-50 171.9 27.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCD26192.1 - 2.8e-09 35.8 36.1 3.9e-09 35.3 25.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2663 PF10864.3 CCD26192.1 - 0.56 10.4 3.6 20 5.4 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2663) ABC_tran PF00005.22 CCD26193.1 - 8.7e-55 184.7 0.0 2.6e-30 105.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCD26193.1 - 2.1e-52 178.2 38.3 1.4e-32 113.1 8.4 4.3 4 0 0 4 4 4 3 ABC transporter transmembrane region AAA_23 PF13476.1 CCD26193.1 - 3.6e-10 40.5 6.1 1.6e-05 25.3 0.0 3.5 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 CCD26193.1 - 6.9e-10 38.5 4.6 0.00012 21.3 0.8 4.1 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCD26193.1 - 1.1e-07 32.1 2.1 7.7e-06 26.0 0.4 5.9 5 2 1 6 6 6 2 AAA domain AAA_29 PF13555.1 CCD26193.1 - 1.5e-07 30.8 0.1 0.029 13.9 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 CCD26193.1 - 1.6e-07 30.6 0.0 0.0045 16.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CCD26193.1 - 4.4e-07 29.8 0.1 0.005 16.7 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 CCD26193.1 - 2.6e-06 28.2 0.1 0.024 15.4 0.0 3.6 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 CCD26193.1 - 4.8e-06 25.6 0.0 0.007 15.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_16 PF13191.1 CCD26193.1 - 8.8e-06 25.8 0.0 0.079 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 CCD26193.1 - 1.2e-05 24.8 0.0 0.0034 16.8 0.0 2.7 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 CCD26193.1 - 5.4e-05 22.6 0.4 0.05 12.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 CCD26193.1 - 5.5e-05 23.6 2.6 0.35 11.3 0.0 3.9 4 0 0 4 4 3 2 Miro-like protein DUF87 PF01935.12 CCD26193.1 - 0.00015 21.6 0.3 0.91 9.2 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_22 PF13401.1 CCD26193.1 - 0.00015 21.8 1.0 0.96 9.5 0.0 3.8 3 1 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 CCD26193.1 - 0.00017 20.7 0.0 0.43 9.6 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Dynamin_N PF00350.18 CCD26193.1 - 0.00042 20.1 6.7 0.062 13.1 0.2 3.2 3 0 0 3 3 3 2 Dynamin family Adeno_IVa2 PF02456.10 CCD26193.1 - 0.00064 18.4 0.0 0.012 14.2 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein MobB PF03205.9 CCD26193.1 - 0.0015 18.2 0.3 0.77 9.4 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 CCD26193.1 - 0.0023 18.2 0.0 3.3 8.0 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 CCD26193.1 - 0.0028 17.8 1.4 9 6.5 0.1 4.0 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CCD26193.1 - 0.003 17.4 0.3 2.6 7.9 0.0 3.3 3 0 0 3 3 2 1 AAA domain ATP_bind_1 PF03029.12 CCD26193.1 - 0.0036 16.8 0.0 1.4 8.4 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 CCD26193.1 - 0.0065 15.9 0.0 4 6.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Guanylate_kin PF00625.16 CCD26193.1 - 0.015 14.7 0.0 0.83 9.0 0.0 2.6 2 0 0 2 2 2 0 Guanylate kinase AAA_33 PF13671.1 CCD26193.1 - 0.017 14.9 0.0 5.4 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CCD26193.1 - 0.043 13.3 0.0 6.9 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain ERp29_N PF07912.8 CCD26193.1 - 0.055 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 ERp29, N-terminal domain ArgK PF03308.11 CCD26193.1 - 0.068 11.9 0.1 0.45 9.2 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AAA_19 PF13245.1 CCD26193.1 - 0.21 11.3 0.1 3 7.6 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain RRM_1 PF00076.17 CCD26194.1 - 2.3e-16 59.1 0.3 7.3e-09 35.1 0.0 3.7 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD26194.1 - 1.4e-08 34.6 0.1 0.0078 16.1 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Caprin-1_C PF12287.3 CCD26194.1 - 0.24 10.7 4.1 0.37 10.1 2.8 1.3 1 0 0 1 1 1 0 Cytoplasmic activation/proliferation-associated protein-1 C term GRP PF07172.6 CCD26194.1 - 9.7 6.7 20.4 0.22 12.0 7.9 2.3 2 0 0 2 2 2 0 Glycine rich protein family Ribosomal_L7Ae PF01248.21 CCD26195.1 - 6.8e-23 79.9 0.2 1.2e-22 79.2 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CCD26195.1 - 0.00057 19.7 0.0 0.00093 19.0 0.0 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 FGGY_C PF02782.11 CCD26196.1 - 7.9e-69 231.2 0.1 1.8e-68 230.0 0.1 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CCD26196.1 - 1.7e-47 161.8 0.1 7.3e-40 136.8 0.0 2.8 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain MIP PF00230.15 CCD26197.1 - 6.2e-71 238.4 6.2 8.3e-71 238.0 4.3 1.2 1 0 0 1 1 1 1 Major intrinsic protein V-SNARE_C PF12352.3 CCD26198.1 - 4.8e-15 55.3 4.6 4.8e-15 55.3 3.2 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Phage_tail_U PF06141.6 CCD26198.1 - 0.022 14.7 0.1 1.4 8.9 0.0 2.4 2 0 0 2 2 2 0 Phage minor tail protein U RseA_N PF03872.8 CCD26198.1 - 0.028 14.6 1.7 0.041 14.1 0.7 1.8 1 1 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain DUF349 PF03993.7 CCD26198.1 - 0.13 12.4 5.8 0.16 12.1 1.7 2.6 2 1 1 3 3 3 0 Domain of Unknown Function (DUF349) DUF843 PF05814.6 CCD26198.1 - 0.68 9.7 5.0 0.52 10.1 0.3 2.5 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) DUF3552 PF12072.3 CCD26198.1 - 0.86 8.7 13.4 1 8.5 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) DUF2743 PF10899.3 CCD26198.1 - 6.1 6.1 9.1 5.5 6.3 5.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2743) DUF3683 PF12447.3 CCD26198.1 - 7 6.5 8.6 0.75 9.6 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3683) Sec20 PF03908.8 CCD26198.1 - 9.2 6.0 9.5 1.1 8.9 0.4 2.9 1 1 1 3 3 3 0 Sec20 Fer2_3 PF13085.1 CCD26199.1 - 4.3e-33 113.4 0.1 8.3e-33 112.5 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CCD26199.1 - 3.8e-10 39.9 7.9 3.8e-10 39.9 5.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CCD26199.1 - 7.2e-09 35.5 6.1 7.2e-09 35.5 4.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CCD26199.1 - 1.6e-05 25.1 1.1 1.6e-05 25.1 0.7 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CCD26199.1 - 9e-05 22.6 5.7 0.04 14.1 0.3 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CCD26199.1 - 0.00018 21.2 5.3 0.00018 21.2 3.6 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CCD26199.1 - 0.00029 20.5 3.4 0.0041 16.8 0.7 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 CCD26199.1 - 0.0023 18.2 6.3 0.0023 18.2 4.4 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 CCD26199.1 - 0.11 12.8 0.6 0.33 11.3 0.1 1.9 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_15 PF13459.1 CCD26199.1 - 7.6 7.1 8.7 1.3 9.6 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Ecm29 PF13001.2 CCD26200.1 - 3.1e-120 402.0 19.0 7.1e-120 400.8 8.7 3.1 3 0 0 3 3 3 2 Proteasome stabiliser HEAT PF02985.17 CCD26200.1 - 1.7e-12 46.2 5.4 0.0044 16.9 0.0 7.3 8 0 0 8 8 8 3 HEAT repeat Vac14_Fab1_bd PF12755.2 CCD26200.1 - 7.3e-08 32.6 5.2 0.00046 20.5 0.0 6.0 6 1 1 7 7 7 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCD26200.1 - 0.0018 18.6 0.1 57 4.3 0.0 5.8 6 0 0 6 6 6 0 HEAT-like repeat ubiquitin PF00240.18 CCD26201.1 - 3.1e-35 119.3 0.9 3.5e-35 119.2 0.6 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCD26201.1 - 1.2e-20 73.0 0.7 1.3e-20 72.8 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCD26201.1 - 1.4e-06 28.4 0.2 5.7e-06 26.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCD26201.1 - 2.5e-05 24.0 0.0 2.8e-05 23.8 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCD26201.1 - 0.0025 17.6 0.1 0.0052 16.6 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCD26201.1 - 0.0068 16.5 0.1 0.0081 16.3 0.0 1.1 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CCD26201.1 - 0.052 13.5 0.0 0.17 11.9 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 CCD26201.1 - 0.12 10.6 0.8 1.5 7.0 0.2 1.9 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.6 CCD26201.1 - 0.33 10.9 1.8 0.61 10.0 1.2 1.4 1 0 0 1 1 1 0 Tash protein PEST motif ENTH PF01417.15 CCD26202.1 - 1.5e-28 99.1 4.4 2.4e-28 98.5 3.0 1.3 1 0 0 1 1 1 1 ENTH domain VHS PF00790.14 CCD26202.1 - 0.026 14.1 0.6 0.36 10.4 0.4 2.4 1 1 0 1 1 1 0 VHS domain SAP18 PF06487.7 CCD26202.1 - 0.029 14.1 0.5 0.43 10.3 0.0 2.3 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) OAS1_C PF10421.4 CCD26202.1 - 0.032 13.7 0.1 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus zf-C2H2 PF00096.21 CCD26204.1 - 9.5e-06 25.6 23.0 2.9e-05 24.1 2.5 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCD26204.1 - 0.00015 21.9 3.3 0.00015 21.9 2.3 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 CCD26204.1 - 0.0091 16.1 0.7 0.04 14.1 0.5 2.2 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CCD26204.1 - 0.013 15.8 1.4 0.013 15.8 0.9 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger Suf PF05843.9 CCD26205.1 - 0.017 14.8 34.5 0.39 10.4 15.4 2.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF501 PF04417.7 CCD26205.1 - 0.6 9.9 0.0 0.6 9.9 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF501) DUF1117 PF06547.7 CCD26205.1 - 6.8 6.8 5.9 1.6 8.8 1.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1117) Phosphodiest PF01663.17 CCD26206.1 - 6.2e-12 45.5 0.2 1e-11 44.7 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CCD26206.1 - 0.0014 18.0 0.7 0.003 17.0 0.5 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Adeno_100 PF02438.11 CCD26206.1 - 0.016 13.4 0.1 0.026 12.7 0.1 1.2 1 0 0 1 1 1 0 Late 100kD protein Sulfatase PF00884.18 CCD26206.1 - 0.049 12.8 0.1 0.095 11.8 0.1 1.5 1 0 0 1 1 1 0 Sulfatase ACT_3 PF10000.4 CCD26206.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 ACT domain Peptidase_M24 PF00557.19 CCD26207.1 - 1e-37 129.7 0.0 1.6e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CCD26207.1 - 6.9e-13 49.2 0.0 3e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain NPR3 PF03666.8 CCD26208.1 - 2.5e-139 464.6 4.1 2.5e-139 464.6 2.8 3.4 3 1 0 3 3 3 1 Nitrogen Permease regulator of amino acid transport activity 3 HSP70 PF00012.15 CCD26209.1 - 1.8e-271 901.3 8.9 2e-271 901.2 6.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCD26209.1 - 1.4e-17 63.3 0.1 4.2e-16 58.4 0.0 2.5 3 0 0 3 3 3 1 MreB/Mbl protein Hydantoinase_A PF01968.13 CCD26209.1 - 0.0014 17.8 1.5 0.037 13.1 0.0 2.8 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 CCD26209.1 - 0.0014 17.5 2.0 0.044 12.6 0.1 3.0 2 1 1 3 3 3 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 CCD26209.1 - 0.0033 17.0 0.0 0.013 15.1 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain PMBR PF09373.5 CCD26209.1 - 1.2 9.1 0.0 1.2 9.1 0.0 2.8 4 0 0 4 4 4 0 Pseudomurein-binding repeat Septin PF00735.13 CCD26210.1 - 1.6e-105 352.1 10.4 1.6e-105 352.1 7.2 3.0 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CCD26210.1 - 2e-05 24.5 0.4 6.3e-05 22.9 0.3 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCD26210.1 - 0.00019 20.8 0.4 0.00019 20.8 0.2 2.7 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CCD26210.1 - 0.00041 19.5 0.7 0.00041 19.5 0.5 2.2 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 CCD26210.1 - 0.0006 20.3 2.0 0.0007 20.0 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CCD26210.1 - 0.00063 19.9 0.1 0.022 14.8 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.1 CCD26210.1 - 0.0023 17.9 0.1 0.012 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 CCD26210.1 - 0.0048 16.5 0.9 0.014 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 CCD26210.1 - 0.016 15.5 0.3 0.016 15.5 0.2 2.8 2 0 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 CCD26210.1 - 0.028 14.7 0.6 0.028 14.7 0.4 2.6 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CCD26210.1 - 0.033 13.6 2.6 0.043 13.2 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 CCD26210.1 - 0.038 12.9 0.2 0.83 8.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein MobB PF03205.9 CCD26210.1 - 0.082 12.6 1.3 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SLA_LP_auto_ag PF05889.8 CCD26210.1 - 1.5 7.2 6.2 1.8 6.9 3.2 2.0 2 1 0 2 2 2 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GIT_SHD PF08518.6 CCD26211.1 - 8.5e-16 57.0 9.4 8.9e-09 34.5 1.1 3.1 3 0 0 3 3 3 2 Spa2 homology domain (SHD) of GIT DivIC PF04977.10 CCD26211.1 - 0.27 10.7 6.4 0.69 9.4 3.7 2.3 1 1 1 2 2 2 0 Septum formation initiator bZIP_1 PF00170.16 CCD26211.1 - 1.3 9.0 13.9 0.81 9.6 3.5 2.8 1 1 1 2 2 2 0 bZIP transcription factor Ribonucleas_3_3 PF14622.1 CCD26212.1 - 1.5e-22 79.9 0.0 3.1e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CCD26212.1 - 1.2e-07 32.2 0.1 6.2e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease III domain SH3_1 PF00018.23 CCD26214.1 - 7.8e-09 34.7 2.9 9.4e-08 31.3 0.1 3.1 3 0 0 3 3 3 1 SH3 domain SH3_9 PF14604.1 CCD26214.1 - 1.4e-07 30.9 0.1 3.8e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 CCD26214.1 - 5e-07 29.1 1.6 7.5e-06 25.3 1.1 2.3 1 1 0 1 1 1 1 Variant SH3 domain RasGEF PF00617.14 CCD26215.1 - 2.6e-59 200.1 0.2 2.6e-59 200.1 0.1 3.1 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 CCD26215.1 - 2e-16 59.9 0.1 2e-16 59.9 0.1 6.5 6 3 1 7 7 7 1 RasGEF N-terminal motif Gtr1_RagA PF04670.7 CCD26216.1 - 1.8e-68 230.1 1.0 2.3e-68 229.8 0.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 CCD26216.1 - 0.0011 18.8 0.0 0.0031 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCD26216.1 - 0.0058 16.3 0.0 0.014 15.1 0.0 1.8 1 1 0 1 1 1 1 Archaeal ATPase Arf PF00025.16 CCD26216.1 - 0.0062 15.8 0.1 0.028 13.6 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family DUF815 PF05673.8 CCD26216.1 - 0.0068 15.3 0.0 0.024 13.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) SRPRB PF09439.5 CCD26216.1 - 0.057 12.6 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MIF4G PF02854.14 CCD26217.1 - 5.6e-50 169.6 0.2 9.3e-50 168.9 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 CCD26217.1 - 1.7e-26 91.8 2.5 2.1e-26 91.5 0.3 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 DUF1574 PF07611.6 CCD26217.1 - 0.046 12.5 0.6 2.4 6.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1574) DUF1484 PF07363.6 CCD26217.1 - 6.8 7.0 8.2 5.1 7.4 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1484) Glyco_tran_28_C PF04101.11 CCD26218.1 - 1.4e-24 86.6 0.0 2.8e-20 72.6 0.0 2.0 2 0 0 2 2 2 2 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CCD26218.1 - 0.0084 15.3 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 1 Herpes_BLRF2 PF05812.7 CCD26219.1 - 0.0047 16.7 7.0 0.0049 16.6 1.5 2.2 1 1 1 2 2 2 1 Herpesvirus BLRF2 protein SYCE1 PF15233.1 CCD26219.1 - 0.0056 16.6 1.7 0.008 16.1 1.2 1.3 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 DUF2046 PF09755.4 CCD26219.1 - 0.023 13.5 6.9 0.04 12.7 4.3 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) Herpes_UL6 PF01763.11 CCD26219.1 - 0.076 11.1 2.4 0.088 10.9 1.6 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like FXR1P_C PF12235.3 CCD26219.1 - 0.096 12.7 0.5 0.2 11.7 0.4 1.7 1 1 0 1 1 1 0 Fragile X-related 1 protein C terminal RICH PF05062.7 CCD26219.1 - 1.4 9.1 6.8 0.33 11.1 1.7 2.0 2 0 0 2 2 2 0 RICH domain Spt4 PF06093.8 CCD26220.1 - 0.43 10.5 2.2 10 6.1 0.2 2.7 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger OrfB_Zn_ribbon PF07282.6 CCD26220.1 - 5.8 6.6 6.9 21 4.8 0.5 2.7 1 1 1 2 2 2 0 Putative transposase DNA-binding domain PEMT PF04191.8 CCD26221.1 - 7.7e-51 170.6 21.1 2.2e-29 101.6 1.9 3.9 3 1 0 3 3 3 2 Phospholipid methyltransferase CSTF2_hinge PF14327.1 CCD26222.1 - 1.2e-23 82.9 1.9 1.2e-23 82.9 1.3 3.5 4 0 0 4 4 4 1 Hinge domain of cleavage stimulation factor subunit 2 His_Phos_1 PF00300.17 CCD26223.1 - 4.2e-17 62.6 0.0 8.1e-17 61.7 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PALP PF00291.20 CCD26224.1 - 4.1e-57 193.7 0.0 5.1e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 CCD26224.1 - 2e-13 49.8 0.0 7.4e-09 35.2 0.1 2.6 2 0 0 2 2 2 2 CBS domain DUF1279 PF06916.8 CCD26226.1 - 1.1e-23 83.3 0.0 1.9e-23 82.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Mlo PF03094.10 CCD26226.1 - 0.1 10.7 0.0 0.14 10.2 0.0 1.2 1 0 0 1 1 1 0 Mlo family Ribosomal_L24e PF01246.15 CCD26227.1 - 1.7e-34 117.4 0.4 1.7e-34 117.4 0.3 2.0 2 1 0 2 2 2 1 Ribosomal protein L24e RR_TM4-6 PF06459.7 CCD26227.1 - 1.2 8.9 6.5 1.4 8.7 4.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF2838 PF10998.3 CCD26228.1 - 2.6e-42 143.2 14.9 2.6e-42 143.2 10.3 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2838) Cast PF10174.4 CCD26228.1 - 0.47 8.4 3.9 0.091 10.8 0.1 1.5 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone PPR_2 PF13041.1 CCD26229.1 - 5.5e-13 48.6 2.1 6.4e-07 29.2 0.5 2.9 1 1 1 2 2 2 2 PPR repeat family PPR PF01535.15 CCD26229.1 - 2.4e-05 23.9 0.8 0.22 11.5 0.0 3.8 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 CCD26229.1 - 4.4e-05 23.4 0.2 0.17 12.2 0.0 3.2 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 CCD26229.1 - 0.014 14.8 0.0 1.3 8.5 0.0 2.8 2 0 0 2 2 2 0 PPR repeat Wbp11 PF09429.5 CCD26229.1 - 1.6 8.7 7.9 0.37 10.8 2.5 2.2 2 0 0 2 2 2 0 WW domain binding protein 11 Cgr1 PF03879.9 CCD26230.1 - 6.5e-38 129.2 35.5 7.8e-38 129.0 24.6 1.0 1 0 0 1 1 1 1 Cgr1 family DRY_EERY PF09750.4 CCD26230.1 - 0.46 10.5 11.9 0.65 10.0 8.3 1.4 1 1 0 1 1 1 0 Alternative splicing regulator Rrn6 PF10214.4 CCD26231.1 - 1.3e-127 426.9 16.7 1.9e-127 426.4 11.6 1.2 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Trp_syntA PF00290.15 CCD26232.1 - 1.4e-95 318.7 0.4 2.1e-95 318.1 0.3 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 CCD26232.1 - 4.7e-47 160.7 1.4 7.6e-47 160.0 0.3 1.7 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 CCD26232.1 - 0.0078 15.4 0.2 0.33 10.1 0.0 2.3 2 0 0 2 2 2 1 PcrB family Ribosomal_L3 PF00297.17 CCD26233.1 - 5.7e-120 399.6 9.3 6.9e-120 399.3 6.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Pkinase PF00069.20 CCD26235.1 - 1.2e-50 172.1 0.0 1.8e-50 171.4 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26235.1 - 1.7e-17 63.4 0.0 2.3e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCD26235.1 - 1.1e-06 28.6 0.0 3.7e-06 26.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCD26235.1 - 0.002 17.7 0.1 0.0059 16.2 0.1 1.9 1 1 0 1 1 1 1 Choline/ethanolamine kinase Aconitase_B_N PF11791.3 CCD26235.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Aconitate B N-terminal domain TP_methylase PF00590.15 CCD26236.1 - 5.2e-37 127.5 0.0 9e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 CCD26236.1 - 4e-05 23.8 0.0 9.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CCD26236.1 - 0.0071 15.6 0.4 0.36 10.1 0.1 2.6 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CCD26236.1 - 0.014 14.4 0.3 0.04 12.8 0.1 1.9 2 0 0 2 2 2 0 Sirohaem biosynthesis protein central Hydrolase_like PF13242.1 CCD26237.1 - 1.7e-24 85.3 0.0 3.6e-24 84.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 CCD26237.1 - 9.4e-24 83.2 0.0 1.6e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCD26237.1 - 0.00011 22.4 0.3 0.69 10.1 0.0 3.5 2 2 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCD26237.1 - 0.00095 19.6 0.0 0.22 11.9 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase CIAPIN1 PF05093.8 CCD26238.1 - 5.9e-35 119.3 5.0 5.9e-35 119.3 3.5 2.3 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF4551 PF15087.1 CCD26238.1 - 0.21 9.9 1.9 0.27 9.5 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-CSL PF05207.8 CCD26238.1 - 8.5 5.9 9.2 56 3.3 6.4 2.4 1 1 0 1 1 1 0 CSL zinc finger Flavoprotein PF02441.14 CCD26239.1 - 2.2e-43 147.0 0.1 5.1e-43 145.8 0.1 1.7 1 0 0 1 1 1 1 Flavoprotein Trm112p PF03966.11 CCD26240.1 - 4.9e-20 71.6 0.1 6.8e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Trm112p-like protein NOB1_Zn_bind PF08772.6 CCD26241.1 - 5.9e-28 96.5 0.7 5.9e-28 96.5 0.5 1.9 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like zf-FCS PF06467.9 CCD26241.1 - 0.042 13.4 0.4 0.13 11.9 0.3 1.9 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF3475 PF11961.3 CCD26241.1 - 0.091 12.6 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3475) SGS PF05002.10 CCD26242.1 - 1.1e-27 95.6 1.5 1.1e-27 95.6 1.1 2.5 2 0 0 2 2 2 1 SGS domain CS PF04969.11 CCD26242.1 - 2.5e-14 53.5 0.4 5.6e-14 52.4 0.2 1.6 1 0 0 1 1 1 1 CS domain TPR_16 PF13432.1 CCD26242.1 - 0.0061 17.2 0.1 0.018 15.7 0.1 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCD26242.1 - 0.012 16.1 0.1 0.16 12.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCD26242.1 - 0.012 15.8 1.3 0.2 11.9 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCD26242.1 - 0.015 15.1 6.3 6.5 6.9 0.4 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCD26242.1 - 0.05 13.3 11.2 0.31 10.9 0.4 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCD26242.1 - 0.22 11.1 7.5 0.38 10.4 2.1 2.4 1 1 0 2 2 2 0 TPR repeat Peptidase_M73 PF12389.3 CCD26244.1 - 0.0059 16.0 0.5 0.0063 15.9 0.3 1.2 1 0 0 1 1 1 1 Camelysin metallo-endopeptidase TRAPP PF04051.11 CCD26245.1 - 6.8e-35 119.8 0.0 1e-34 119.2 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Dsl1_N PF11988.3 CCD26245.1 - 0.0015 17.4 0.2 0.024 13.5 0.0 2.0 2 0 0 2 2 2 2 Retrograde transport protein Dsl1 N terminal Acyltransferase PF01553.16 CCD26246.1 - 4.1e-08 32.7 0.0 8e-07 28.5 0.0 2.6 2 1 0 2 2 2 1 Acyltransferase Methyltransf_28 PF02636.12 CCD26247.1 - 4.1e-10 39.4 0.0 6.4e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Orthopox_F14 PF06076.7 CCD26248.1 - 0.02 14.9 0.2 0.22 11.5 0.0 2.5 3 0 0 3 3 3 0 Orthopoxvirus F14 protein DUF4407 PF14362.1 CCD26248.1 - 0.36 9.7 5.1 0.33 9.8 2.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2839 PF10999.3 CCD26248.1 - 0.76 9.8 0.0 0.76 9.8 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) Pmp3 PF01679.12 CCD26249.1 - 1.1e-19 69.7 7.1 1.2e-19 69.6 4.9 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BTP PF05232.7 CCD26249.1 - 0.017 14.8 4.1 0.02 14.6 2.8 1.1 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family E1-E2_ATPase PF00122.15 CCD26254.1 - 5.9e-47 159.6 0.1 5.9e-47 159.6 0.1 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CCD26254.1 - 1.1e-36 127.3 0.0 9.5e-36 124.2 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CCD26254.1 - 1.3e-25 89.2 11.9 3.5e-13 49.4 1.5 3.3 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.2 CCD26254.1 - 8.4e-16 58.6 0.0 1.7e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCD26254.1 - 5.2e-05 22.9 8.5 0.00039 20.0 0.1 4.1 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase Corona_nucleoca PF00937.13 CCD26254.1 - 0.66 8.8 2.5 0.99 8.2 1.7 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF1656 PF07869.7 CCD26254.1 - 5.7 6.8 8.2 0.43 10.4 1.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) tRNA-synt_1b PF00579.20 CCD26255.1 - 8.9e-74 248.2 0.1 1.1e-73 247.8 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Securin PF04856.8 CCD26255.1 - 0.035 13.7 0.3 0.05 13.3 0.2 1.3 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor WD40 PF00400.27 CCD26256.1 - 4.7e-55 181.6 20.9 5.2e-11 41.9 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCD26256.1 - 0.00065 19.1 0.2 10 5.6 0.0 5.0 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.9 CCD26256.1 - 0.035 12.8 4.1 0.74 8.5 0.5 3.0 2 1 1 3 3 3 0 Coatomer WD associated region IKI3 PF04762.7 CCD26256.1 - 0.11 10.3 2.9 0.66 7.7 2.0 1.9 1 1 0 1 1 1 0 IKI3 family zf-C3HC4_3 PF13920.1 CCD26257.1 - 1.3e-06 27.9 8.2 1.3e-06 27.9 5.7 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Peptidase_S76 PF13611.1 CCD26257.1 - 0.018 15.1 0.2 0.068 13.2 0.1 2.0 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 Mur_ligase_C PF02875.16 CCD26257.1 - 0.032 14.2 0.0 0.072 13.1 0.0 1.5 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain Pex2_Pex12 PF04757.9 CCD26258.1 - 3.6e-31 108.3 4.3 7.2e-31 107.3 3.0 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CCD26258.1 - 3e-08 33.5 16.4 5.4e-08 32.7 11.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCD26258.1 - 6.8e-08 32.2 16.2 1.1e-07 31.5 11.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCD26258.1 - 8.3e-07 28.5 16.4 1.3e-06 27.9 11.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCD26258.1 - 5.6e-06 25.9 12.6 1.2e-05 24.9 8.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCD26258.1 - 3.3e-05 23.4 14.6 5.9e-05 22.6 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCD26258.1 - 0.0058 16.4 15.7 0.011 15.6 10.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCD26258.1 - 0.011 15.4 5.7 0.011 15.4 4.0 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 CCD26258.1 - 0.027 14.5 13.1 0.069 13.2 9.1 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_6 PF14835.1 CCD26258.1 - 0.08 12.7 10.6 0.17 11.7 7.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Ank PF00023.25 CCD26259.1 - 6.7e-39 129.7 0.5 1.2e-08 34.3 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Ank_2 PF12796.2 CCD26259.1 - 2.2e-36 124.0 0.0 1.2e-21 76.8 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCD26259.1 - 1.4e-34 117.3 1.9 5e-10 39.2 0.6 5.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD26259.1 - 8.2e-30 99.8 0.2 4.3e-05 23.3 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 CCD26259.1 - 1.5e-27 95.3 0.3 1.7e-08 34.7 0.1 4.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) zf-DHHC PF01529.15 CCD26259.1 - 1.2e-24 86.6 3.0 1.2e-24 86.6 2.1 2.3 2 1 1 3 3 3 1 DHHC palmitoyltransferase Wzy_C PF04932.10 CCD26259.1 - 0.23 11.2 3.9 20 4.8 0.0 3.4 3 0 0 3 3 3 0 O-Antigen ligase XPG_N PF00752.12 CCD26260.1 - 3.5e-24 84.9 0.0 8.5e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCD26260.1 - 3.7e-21 74.9 0.0 1e-20 73.5 0.0 1.8 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CCD26260.1 - 0.0018 18.4 0.0 0.0051 17.0 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 CCD26260.1 - 0.038 13.8 0.0 2.4 8.0 0.0 2.9 2 0 0 2 2 2 0 Helix-hairpin-helix motif DUF179 PF02622.10 CCD26260.1 - 0.05 13.2 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized ACR, COG1678 Fasciclin PF02469.17 CCD26261.1 - 0.0018 18.3 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain Cellulase PF00150.13 CCD26262.1 - 1.1e-14 54.2 17.2 6.4e-14 51.8 11.9 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Apc13p PF05839.6 CCD26263.1 - 7.1e-05 22.7 3.3 0.00011 22.1 2.3 1.4 1 1 0 1 1 1 1 Apc13p protein AAA_2 PF07724.9 CCD26264.1 - 8.1e-49 165.8 0.1 2e-46 158.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CCD26264.1 - 4.9e-25 87.2 0.1 1.6e-24 85.5 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CCD26264.1 - 1.3e-21 77.1 0.1 2.2e-11 44.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCD26264.1 - 8.1e-15 55.2 3.2 0.0003 20.8 0.0 4.7 3 2 1 5 5 5 3 AAA ATPase domain AAA_5 PF07728.9 CCD26264.1 - 4.1e-14 52.4 0.3 5.8e-10 39.0 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCD26264.1 - 8e-10 38.9 0.4 0.00022 21.3 0.0 3.5 3 1 0 3 3 2 2 AAA domain IstB_IS21 PF01695.12 CCD26264.1 - 7.3e-08 32.0 0.0 0.0094 15.3 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 CCD26264.1 - 1.8e-06 27.5 0.0 5.5e-05 22.6 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 CCD26264.1 - 4.1e-06 26.6 12.9 0.00036 20.3 0.2 5.1 4 2 0 4 4 3 1 Archaeal ATPase AAA_17 PF13207.1 CCD26264.1 - 1.2e-05 26.0 2.9 0.49 11.2 0.0 3.7 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCD26264.1 - 3.7e-05 24.0 4.5 0.031 14.5 0.0 3.5 3 1 1 4 4 2 2 AAA domain NACHT PF05729.7 CCD26264.1 - 6e-05 22.7 0.0 0.08 12.5 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.1 CCD26264.1 - 7.6e-05 22.1 0.0 0.1 12.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 CCD26264.1 - 8.9e-05 21.6 0.1 0.0095 15.0 0.0 3.2 2 1 0 2 2 2 1 Zeta toxin DUF258 PF03193.11 CCD26264.1 - 0.00012 21.3 0.5 0.035 13.2 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 CCD26264.1 - 0.00016 21.9 2.5 0.14 12.4 0.0 3.4 3 1 0 3 3 3 1 ABC transporter AAA_28 PF13521.1 CCD26264.1 - 0.00059 19.8 0.0 0.97 9.3 0.0 3.0 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 CCD26264.1 - 0.00081 19.3 0.0 0.096 12.6 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 CCD26264.1 - 0.0012 18.3 0.0 0.9 9.0 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CCD26264.1 - 0.0014 18.7 0.0 2.6 8.2 0.0 2.9 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.8 CCD26264.1 - 0.0015 17.5 1.3 0.45 9.3 0.2 3.5 2 2 0 2 2 2 1 Protein of unknown function (DUF815) MobB PF03205.9 CCD26264.1 - 0.0027 17.4 0.0 3.2 7.4 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 CCD26264.1 - 0.0029 17.3 0.0 3.1 7.6 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 CCD26264.1 - 0.0043 16.4 1.5 2.4 7.5 0.1 3.1 3 2 0 3 3 2 1 AAA domain PhoH PF02562.11 CCD26264.1 - 0.0058 15.8 0.0 0.38 9.9 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein UPF0079 PF02367.12 CCD26264.1 - 0.0067 16.0 0.0 3.9 7.1 0.0 3.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SRP54 PF00448.17 CCD26264.1 - 0.0078 15.6 0.0 1.3 8.4 0.0 2.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 CCD26264.1 - 0.0085 15.2 0.1 0.86 8.7 0.0 2.8 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.1 CCD26264.1 - 0.0087 15.6 0.0 6.8 6.2 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CCD26264.1 - 0.0087 15.6 0.0 4.4 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.2 CCD26264.1 - 0.01 15.4 0.1 1.7 8.0 0.1 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region D1 T2SE PF00437.15 CCD26264.1 - 0.039 12.8 4.0 0.17 10.7 0.8 2.7 2 1 0 2 2 2 0 Type II/IV secretion system protein Miro PF08477.8 CCD26264.1 - 0.044 14.2 0.5 0.5 10.8 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein AAA_21 PF13304.1 CCD26264.1 - 0.051 13.5 8.8 2.2 8.1 0.0 4.4 3 1 1 5 5 5 0 AAA domain ResIII PF04851.10 CCD26264.1 - 0.054 13.3 5.8 4 7.2 0.0 4.3 3 1 1 4 4 4 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 CCD26264.1 - 0.074 12.9 0.0 7.9 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 CCD26264.1 - 0.098 12.2 0.1 2.2 7.8 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) V_ATPase_I PF01496.14 CCD26264.1 - 5.9 4.6 8.6 9 3.9 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SET PF00856.23 CCD26265.1 - 1.2e-13 51.6 0.0 4.9e-13 49.7 0.0 1.9 1 1 0 1 1 1 1 SET domain Pex24p PF06398.6 CCD26266.1 - 1.1e-75 254.7 10.0 1.5e-75 254.2 7.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF639 PF04842.7 CCD26266.1 - 0.058 11.5 0.9 0.093 10.8 0.1 1.7 2 0 0 2 2 2 0 Plant protein of unknown function (DUF639) Rpr2 PF04032.11 CCD26267.1 - 2.1e-11 43.5 0.3 2.1e-11 43.5 0.2 1.9 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.1 CCD26267.1 - 0.0038 16.3 1.7 0.11 11.6 0.1 2.3 2 0 0 2 2 2 1 zinc-ribbon domain zinc_ribbon_2 PF13240.1 CCD26267.1 - 0.15 11.6 2.7 0.5 9.9 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 CCD26267.1 - 0.17 11.7 1.2 0.44 10.3 0.9 1.6 1 1 0 1 1 1 0 Double zinc ribbon zf-HIT PF04438.11 CCD26267.1 - 0.64 9.7 3.3 2.4 7.8 0.2 2.2 2 0 0 2 2 2 0 HIT zinc finger Pkinase PF00069.20 CCD26268.1 - 3.4e-77 259.1 0.1 6.9e-77 258.1 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26268.1 - 3.9e-39 134.2 0.0 6.6e-39 133.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 CCD26268.1 - 2.2e-20 72.5 1.6 2.2e-20 72.5 1.1 2.6 3 0 0 3 3 3 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 CCD26268.1 - 1.1e-09 37.7 0.0 2.4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like YukC PF10140.4 CCD26268.1 - 9.6e-05 21.1 0.2 0.00017 20.2 0.2 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 CCD26268.1 - 0.003 16.6 0.1 0.0056 15.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD26268.1 - 0.022 14.4 0.1 0.72 9.5 0.2 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Innate_immun PF12782.2 CCD26268.1 - 8 5.5 18.5 1.2 8.3 10.0 1.7 2 0 0 2 2 2 0 Invertebrate innate immunity transcript family Gemini_AL1_M PF08283.6 CCD26270.1 - 0.0071 16.1 0.0 0.023 14.5 0.0 1.8 1 0 0 1 1 1 1 Geminivirus rep protein central domain TRAPP PF04051.11 CCD26271.1 - 6.1e-47 158.9 0.0 1.3e-46 157.9 0.0 1.5 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component MitMem_reg PF13012.1 CCD26271.1 - 0.11 12.5 2.7 0.55 10.3 0.1 2.3 1 1 1 2 2 2 0 Maintenance of mitochondrial structure and function Ribosomal_L27e PF01777.13 CCD26272.1 - 5.6e-37 125.7 7.1 7.7e-37 125.2 4.9 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CCD26272.1 - 0.0003 20.3 1.6 0.00061 19.4 1.1 1.6 1 0 0 1 1 1 1 KOW motif DUF1512 PF07431.7 CCD26272.1 - 0.032 12.9 0.2 0.056 12.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) Mito_carr PF00153.22 CCD26273.1 - 6.9e-09 35.3 0.0 0.006 16.2 0.0 3.5 4 0 0 4 4 4 2 Mitochondrial carrier protein Dpy-30 PF05186.8 CCD26274.1 - 1.3e-15 56.6 0.0 1.7e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif 120_Rick_ant PF12574.3 CCD26274.1 - 0.016 14.2 1.5 0.02 14.0 1.0 1.1 1 0 0 1 1 1 0 120 KDa Rickettsia surface antigen SNARE PF05739.14 CCD26275.1 - 2.6e-12 46.2 5.4 2.6e-12 46.2 3.8 3.2 2 1 1 3 3 3 1 SNARE domain Syntaxin-6_N PF09177.6 CCD26275.1 - 1.5e-05 25.3 9.6 6.7e-05 23.2 3.1 3.1 2 1 1 3 3 3 1 Syntaxin 6, N-terminal FliJ PF02050.11 CCD26275.1 - 0.0019 18.2 5.8 4.2 7.4 1.2 3.1 3 0 0 3 3 3 0 Flagellar FliJ protein Sec20 PF03908.8 CCD26275.1 - 0.0026 17.4 7.4 0.02 14.5 0.0 3.1 2 1 1 3 3 3 1 Sec20 DUF892 PF05974.7 CCD26275.1 - 0.0029 17.4 2.9 0.0098 15.7 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF892) DUF745 PF05335.8 CCD26275.1 - 0.0099 15.4 4.3 1.2 8.5 0.1 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF745) DUF1664 PF07889.7 CCD26275.1 - 0.014 15.2 9.8 1.4 8.7 3.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) SlyX PF04102.7 CCD26275.1 - 0.014 15.7 13.9 1.5 9.2 0.4 4.1 2 2 2 4 4 4 0 SlyX Tweety PF04906.8 CCD26275.1 - 0.023 13.1 7.0 0.56 8.5 1.0 2.5 2 1 0 2 2 2 0 Tweety TMF_TATA_bd PF12325.3 CCD26275.1 - 0.061 13.0 11.3 2.1 8.0 3.2 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 CCD26275.1 - 0.065 12.1 4.3 0.06 12.2 0.6 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 PhoU_div PF01865.11 CCD26275.1 - 0.068 12.3 4.3 0.98 8.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF47 Allexi_40kDa PF05549.6 CCD26275.1 - 0.083 12.1 10.7 0.069 12.4 3.4 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF3080 PF11279.3 CCD26275.1 - 0.089 11.9 2.1 0.087 11.9 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3080) RmuC PF02646.11 CCD26275.1 - 0.1 11.4 8.6 0.21 10.3 0.3 2.7 2 1 1 3 3 3 0 RmuC family OmpH PF03938.9 CCD26275.1 - 0.11 12.4 5.3 3.7 7.4 3.7 2.1 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) SSFA2_C PF14723.1 CCD26275.1 - 0.13 12.0 2.2 2.4 7.8 0.2 2.2 2 0 0 2 2 2 0 Sperm-specific antigen 2 C-terminus Baculo_PEP_C PF04513.7 CCD26275.1 - 0.13 12.0 8.3 0.21 11.4 4.1 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Baculo_p24 PF05073.7 CCD26275.1 - 0.16 11.4 6.9 0.06 12.9 2.3 1.8 2 0 0 2 2 2 0 Baculovirus P24 capsid protein FlaC_arch PF05377.6 CCD26275.1 - 0.17 11.8 6.9 6.5 6.7 0.6 3.4 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Hanta_nucleocap PF00846.13 CCD26275.1 - 0.17 10.5 3.7 0.073 11.7 1.1 1.6 2 0 0 2 2 2 0 Hantavirus nucleocapsid protein Laminin_II PF06009.7 CCD26275.1 - 0.17 11.6 11.2 0.81 9.4 4.6 2.8 2 1 0 2 2 2 0 Laminin Domain II RRF PF01765.14 CCD26275.1 - 0.21 11.0 4.5 0.97 8.8 0.1 2.7 1 1 2 3 3 3 0 Ribosome recycling factor Cob_adeno_trans PF01923.13 CCD26275.1 - 0.22 11.3 2.4 0.24 11.1 0.4 1.9 2 1 0 2 2 2 0 Cobalamin adenosyltransferase DUF1640 PF07798.6 CCD26275.1 - 0.25 11.3 5.4 3.3 7.7 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) DUF724 PF05266.9 CCD26275.1 - 0.28 10.8 6.7 3.3 7.2 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF724) COG2 PF06148.6 CCD26275.1 - 0.31 10.8 6.9 8.9 6.1 1.3 3.1 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Perilipin PF03036.11 CCD26275.1 - 0.32 9.7 2.5 0.86 8.3 0.1 2.1 1 1 0 2 2 2 0 Perilipin family Nup88 PF10168.4 CCD26275.1 - 0.37 8.5 4.3 0.12 10.1 0.2 1.8 2 0 0 2 2 2 0 Nuclear pore component DUF2408 PF10303.4 CCD26275.1 - 0.39 10.8 7.0 8.2 6.5 4.0 3.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2408) GP41 PF00517.12 CCD26275.1 - 0.43 10.1 6.1 2.6 7.5 0.1 2.7 2 1 0 2 2 2 0 Retroviral envelope protein TPR_MLP1_2 PF07926.7 CCD26275.1 - 0.63 9.7 9.6 2.5 7.8 2.8 2.5 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF87 PF01935.12 CCD26275.1 - 0.74 9.5 5.4 0.26 11.0 1.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 Med9 PF07544.8 CCD26275.1 - 0.76 9.5 12.9 1.1 9.0 0.0 4.2 2 2 3 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 UPF0242 PF06785.6 CCD26275.1 - 0.77 8.3 10.2 0.093 11.4 1.1 2.0 1 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) PhoU PF01895.14 CCD26275.1 - 0.78 10.2 7.7 2.3 8.7 0.1 3.0 2 1 1 3 3 3 0 PhoU domain Apolipoprotein PF01442.13 CCD26275.1 - 1.1 8.7 6.1 2.9 7.3 0.1 2.9 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain FliD_N PF02465.13 CCD26275.1 - 1.2 9.4 9.3 0.21 11.9 1.0 2.8 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus TMPIT PF07851.8 CCD26275.1 - 1.6 7.7 8.0 4.7 6.1 0.4 2.6 1 1 2 3 3 3 0 TMPIT-like protein P4Ha_N PF08336.6 CCD26275.1 - 1.9 8.3 7.2 12 5.7 0.2 3.2 3 0 0 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region HR1 PF02185.11 CCD26275.1 - 2 8.2 13.0 7 6.4 0.3 3.3 2 1 1 3 3 3 0 Hr1 repeat Prefoldin_3 PF13758.1 CCD26275.1 - 2.1 8.2 6.5 1 9.1 1.9 2.3 2 1 1 3 3 3 0 Prefoldin subunit Vps5 PF09325.5 CCD26275.1 - 2.2 7.4 8.8 6.5 5.9 0.4 2.8 2 1 0 3 3 3 0 Vps5 C terminal like CASP_C PF08172.7 CCD26275.1 - 2.5 7.0 6.9 0.55 9.2 0.3 2.6 3 0 0 3 3 3 0 CASP C terminal Tropomyosin PF00261.15 CCD26275.1 - 2.7 7.0 8.5 1.4 7.9 0.7 2.9 3 0 0 3 3 3 0 Tropomyosin Glutaredoxin2_C PF04399.8 CCD26275.1 - 2.9 7.4 6.0 4.8 6.7 0.2 2.7 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain PspA_IM30 PF04012.7 CCD26275.1 - 3.1 7.0 6.2 2.8 7.2 0.4 2.6 2 1 0 2 2 2 0 PspA/IM30 family Fib_alpha PF08702.5 CCD26275.1 - 3.7 7.6 13.1 2.6 8.1 1.1 2.8 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Occludin_ELL PF07303.8 CCD26275.1 - 4.1 8.1 7.0 15 6.3 1.1 2.9 2 1 0 2 2 2 0 Occludin homology domain USP8_interact PF08941.5 CCD26275.1 - 4.3 6.6 6.1 1 8.6 0.8 2.2 2 1 1 3 3 3 0 USP8 interacting Prefoldin_2 PF01920.15 CCD26275.1 - 5 6.9 12.6 8.3 6.2 3.7 2.8 2 1 0 2 2 2 0 Prefoldin subunit Prefoldin PF02996.12 CCD26275.1 - 5 6.7 10.6 1.1 8.8 0.9 3.2 2 1 2 4 4 4 0 Prefoldin subunit V-SNARE_C PF12352.3 CCD26275.1 - 6.3 6.9 8.5 19 5.3 2.3 2.9 2 1 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Cluap1 PF10234.4 CCD26275.1 - 6.4 5.8 11.4 4.7 6.3 0.2 2.8 2 1 0 2 2 2 0 Clusterin-associated protein-1 Fzo_mitofusin PF04799.8 CCD26275.1 - 6.9 6.0 8.6 21 4.4 3.2 2.8 2 1 0 2 2 2 0 fzo-like conserved region Syntaxin PF00804.20 CCD26275.1 - 7.8 6.7 16.7 0.2 11.8 4.5 2.7 1 1 1 2 2 1 0 Syntaxin Ibs_toxin PF13956.1 CCD26275.1 - 8.8 6.2 11.5 15 5.5 8.0 1.4 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Pkinase PF00069.20 CCD26276.1 - 6e-64 215.6 0.1 9.3e-64 215.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26276.1 - 3.2e-31 108.3 0.0 5e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD26276.1 - 2.4e-09 36.5 0.0 4.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCD26276.1 - 0.0053 16.5 0.0 0.0087 15.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCD26276.1 - 0.0077 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCD26276.1 - 0.013 14.8 0.1 0.065 12.5 0.0 2.1 2 0 0 2 2 2 0 RIO1 family SpoU_sub_bind PF08032.7 CCD26276.1 - 0.22 11.6 2.1 0.27 11.4 0.2 2.0 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding Methyltransf_4 PF02390.12 CCD26277.1 - 0.0073 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 CCD26277.1 - 0.1 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3020 PF11223.3 CCD26278.1 - 9.7e-12 45.0 4.4 9.7e-12 45.0 3.1 8.6 8 1 0 8 8 8 1 Protein of unknown function (DUF3020) RNA_Me_trans PF04252.8 CCD26279.1 - 5.1e-82 274.0 0.0 5.7e-82 273.8 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase PRP3 PF08572.5 CCD26280.1 - 8.2e-57 192.1 21.9 1.8e-56 191.0 14.3 1.9 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CCD26280.1 - 9.2e-32 109.4 1.1 9.2e-32 109.4 0.8 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1115) IncA PF04156.9 CCD26280.1 - 6.6 6.2 7.9 1 8.9 1.7 2.1 2 0 0 2 2 2 0 IncA protein PBP PF01161.15 CCD26281.1 - 4.7e-29 101.1 0.1 5.7e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein MAT1 PF06391.8 CCD26282.1 - 4.4e-49 166.7 27.2 4.9e-48 163.3 18.9 2.0 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_3 PF13920.1 CCD26282.1 - 0.003 17.1 5.3 0.0053 16.4 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD26282.1 - 0.0041 17.1 6.2 0.0099 15.8 4.3 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCD26282.1 - 0.0069 16.0 5.3 0.032 13.8 3.7 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCD26282.1 - 0.015 15.1 5.9 0.03 14.1 4.1 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 CCD26282.1 - 0.071 12.8 8.2 0.41 10.4 5.9 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-piccolo PF05715.8 CCD26282.1 - 0.23 11.5 1.5 0.46 10.5 1.0 1.5 1 0 0 1 1 1 0 Piccolo Zn-finger zf-RING_4 PF14570.1 CCD26282.1 - 0.91 9.1 8.6 8.3 6.0 6.3 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain FliS PF02561.9 CCD26282.1 - 0.96 9.3 6.5 0.2 11.5 1.4 2.0 2 1 1 3 3 3 0 Flagellar protein FliS zf-RING_UBOX PF13445.1 CCD26282.1 - 1.8 8.3 6.7 1.3 8.7 3.1 2.1 2 0 0 2 2 2 0 RING-type zinc-finger DUF87 PF01935.12 CCD26282.1 - 4 7.1 8.2 4.3 7.0 4.2 1.8 1 1 1 2 2 2 0 Domain of unknown function DUF87 TMEM51 PF15345.1 CCD26283.1 - 0.033 13.8 0.5 0.033 13.8 0.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 MRP-L28 PF09812.4 CCD26284.1 - 1.5e-29 102.8 1.2 2e-29 102.4 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 TPR_MLP1_2 PF07926.7 CCD26284.1 - 0.049 13.3 2.1 0.13 11.9 1.4 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4375 PF14300.1 CCD26284.1 - 0.077 12.9 0.1 0.97 9.4 0.1 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF4375) tRNA-synt_His PF13393.1 CCD26284.1 - 0.11 11.5 0.3 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 Histidyl-tRNA synthetase zf-H2C2_2 PF13465.1 CCD26285.1 - 0.0039 17.3 9.3 0.0092 16.2 0.3 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCD26285.1 - 0.0097 16.2 4.7 0.0097 16.2 3.2 3.8 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD26285.1 - 0.021 15.1 3.1 0.021 15.1 2.1 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger GATA PF00320.22 CCD26285.1 - 0.18 11.1 2.1 0.29 10.5 0.2 2.3 2 0 0 2 2 2 0 GATA zinc finger zf-BED PF02892.10 CCD26285.1 - 0.74 9.6 7.6 0.87 9.3 2.7 3.0 2 0 0 2 2 2 0 BED zinc finger CDC24 PF06395.6 CCD26286.1 - 1.6e-37 127.4 3.9 2.5e-37 126.8 0.6 3.0 3 0 0 3 3 3 1 CDC24 Calponin RhoGEF PF00621.15 CCD26286.1 - 7.9e-31 107.3 7.9 7.9e-31 107.3 5.4 3.6 3 0 0 3 3 3 1 RhoGEF domain PH_10 PF15411.1 CCD26286.1 - 2.4e-17 63.2 7.3 1.4e-10 41.3 0.5 4.0 3 1 0 4 4 4 2 Pleckstrin homology domain SR-25 PF10500.4 CCD26286.1 - 0.0086 15.5 8.0 0.0086 15.5 5.5 5.3 5 1 0 5 5 5 1 Nuclear RNA-splicing-associated protein Cyclin_N PF00134.18 CCD26287.1 - 4e-25 87.8 3.1 8.8e-25 86.7 2.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyto_heme_lyase PF01265.12 CCD26288.1 - 1.1e-70 238.2 0.8 1.3e-70 237.9 0.6 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PK PF00224.16 CCD26289.1 - 5e-166 551.5 1.9 6.2e-166 551.2 1.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CCD26289.1 - 7.9e-29 99.5 0.0 2.8e-28 97.8 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CCD26289.1 - 6.2e-05 21.9 0.5 0.00013 20.8 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Sulfotransfer_1 PF00685.22 CCD26289.1 - 0.18 11.0 0.0 0.37 10.0 0.0 1.5 1 0 0 1 1 1 0 Sulfotransferase domain HLH PF00010.21 CCD26290.1 - 1.6e-16 59.7 1.4 5.8e-16 57.9 1.0 2.1 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Glyco_transf_90 PF05686.7 CCD26290.1 - 0.011 14.4 0.9 0.011 14.4 0.6 1.6 1 1 1 2 2 2 0 Glycosyl transferase family 90 Inos-1-P_synth PF01658.12 CCD26290.1 - 3.6 7.4 8.2 1.4 8.7 1.5 2.6 1 1 0 2 2 2 0 Myo-inositol-1-phosphate synthase Hyphal_reg_CWP PF11765.3 CCD26291.1 - 2.7e-16 59.2 14.4 2.7e-16 59.2 10.0 1.5 1 1 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Mis12 PF05859.7 CCD26292.1 - 6.5e-40 136.2 2.5 1.5e-39 135.0 1.7 1.7 1 0 0 1 1 1 1 Mis12 protein NPV_P10 PF05531.7 CCD26292.1 - 9.3 6.5 9.0 3.7 7.8 0.9 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein TGS PF02824.16 CCD26293.1 - 5.2e-22 77.4 0.0 1e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CCD26293.1 - 1.1e-17 64.1 0.1 2.1e-17 63.1 0.1 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCD26293.1 - 4.5e-10 39.0 0.1 1e-09 37.8 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCD26293.1 - 0.0011 18.8 0.5 0.8 9.5 0.0 2.2 1 1 1 2 2 2 2 Dynamin family ArgK PF03308.11 CCD26293.1 - 0.0068 15.2 0.2 0.015 14.1 0.1 1.5 1 0 0 1 1 1 1 ArgK protein GTP_EFTU PF00009.22 CCD26293.1 - 0.0071 15.8 0.1 10 5.4 0.0 3.6 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain Miro PF08477.8 CCD26293.1 - 0.012 16.1 0.0 0.022 15.2 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein Arf PF00025.16 CCD26293.1 - 0.14 11.3 0.2 1.5 8.0 0.0 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_28 PF13521.1 CCD26293.1 - 0.17 11.8 0.0 0.29 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb1_5 PF04998.12 CCD26294.1 - 1.7e-99 332.5 0.7 1.7e-99 332.5 0.5 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CCD26294.1 - 3.9e-65 218.8 0.1 1.6e-64 216.8 0.1 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CCD26294.1 - 1.4e-39 135.3 0.3 1.1e-38 132.4 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CCD26294.1 - 1e-24 86.3 0.0 9.3e-24 83.2 0.0 2.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 CCD26294.1 - 6.9e-21 74.8 2.5 6.9e-21 74.8 1.8 4.9 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 SWIRM PF04433.12 CCD26295.1 - 3.9e-14 52.5 0.0 8.4e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain NT-C2 PF10358.4 CCD26295.1 - 0.059 12.8 1.6 0.13 11.7 0.0 2.3 2 1 1 3 3 3 0 N-terminal C2 in EEIG1 and EHBP1 proteins DUF3589 PF12141.3 CCD26296.1 - 1.6e-93 313.6 4.2 3.8e-92 309.0 2.9 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) bZIP_2 PF07716.10 CCD26298.1 - 2.9e-08 33.3 7.1 2.9e-08 33.3 4.9 2.8 2 1 1 3 3 3 1 Basic region leucine zipper DUF2259 PF10016.4 CCD26298.1 - 3.1 7.4 9.8 0.45 10.1 0.4 2.1 1 1 1 2 2 2 0 Predicted secreted protein (DUF2259) Presenilin PF01080.12 CCD26298.1 - 6.1 5.5 14.6 5 5.8 9.5 1.4 1 1 0 1 1 1 0 Presenilin FAD-SLDH PF12318.3 CCD26298.1 - 8.7 5.9 7.9 0.49 10.0 0.8 2.2 1 1 2 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase ARL2_Bind_BART PF11527.3 CCD26299.1 - 0.04 13.7 0.3 0.099 12.4 0.0 1.8 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Sulfate_tra_GLY PF13792.1 CCD26299.1 - 2.2 8.0 5.9 0.2 11.3 0.8 1.9 2 0 0 2 2 2 0 Sulfate transporter N-terminal domain with GLY motif LRS4 PF10422.4 CCD26300.1 - 3.6e-20 72.3 27.6 3.6e-20 72.3 19.2 2.2 1 1 1 2 2 2 1 Monopolin complex subunit LRS4 DivIC PF04977.10 CCD26300.1 - 2.3 7.7 7.5 0.097 12.1 0.8 2.1 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 CCD26300.1 - 2.3 8.6 12.4 0.48 10.8 2.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 CCD26300.1 - 2.9 7.4 8.4 0.18 11.3 0.6 2.1 2 0 0 2 2 2 0 IncA protein Mannosyl_trans3 PF11051.3 CCD26301.1 - 2.3e-66 223.9 0.8 2.3e-66 223.9 0.6 1.6 2 0 0 2 2 2 1 Mannosyltransferase putative ABC2_membrane PF01061.19 CCD26302.1 - 8.1e-64 214.6 54.1 3.7e-35 120.9 20.1 3.2 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.22 CCD26302.1 - 3.8e-28 98.4 0.0 3e-16 59.9 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCD26302.1 - 2e-25 88.4 17.0 9.3e-23 79.8 0.3 3.3 3 0 0 3 3 2 2 CDR ABC transporter AAA_21 PF13304.1 CCD26302.1 - 7.4e-06 26.1 8.1 0.0082 16.1 0.1 4.3 3 1 1 4 4 4 2 AAA domain DUF258 PF03193.11 CCD26302.1 - 4.3e-05 22.7 0.1 7.9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 CCD26302.1 - 0.00014 21.1 0.4 0.0038 16.4 0.3 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CCD26302.1 - 0.0009 19.3 0.1 0.0024 18.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCD26302.1 - 0.0017 18.3 0.4 0.013 15.4 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CCD26302.1 - 0.0019 18.5 0.0 0.0054 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CCD26302.1 - 0.0039 17.5 0.0 0.0083 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 CCD26302.1 - 0.0039 16.2 63.3 0.017 14.1 11.9 3.8 2 2 1 3 3 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 CCD26302.1 - 0.019 14.3 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CCD26302.1 - 0.022 14.2 0.1 0.037 13.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 CCD26302.1 - 0.037 13.5 0.3 0.11 12.0 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CCD26302.1 - 0.11 12.3 0.2 0.69 9.8 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_19 PF13245.1 CCD26302.1 - 0.17 11.6 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain SRP1_TIP1 PF00660.12 CCD26303.1 - 7.1e-35 118.9 2.7 2.9e-34 117.0 1.8 2.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family FAM196 PF15265.1 CCD26303.1 - 2.6 7.1 20.4 3.3 6.8 14.1 1.1 1 0 0 1 1 1 0 FAM196 family Hex_IIIa PF02455.11 CCD26303.1 - 3.5 6.2 12.1 5.8 5.4 8.4 1.4 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) BUD22 PF09073.5 CCD26303.1 - 5 6.0 21.8 6.2 5.7 15.1 1.1 1 0 0 1 1 1 0 BUD22 CytochromB561_N PF09786.4 CCD26303.1 - 8.1 4.7 29.9 9.2 4.5 20.7 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SRP1_TIP1 PF00660.12 CCD26304.1 - 4e-35 119.7 2.9 1.1e-34 118.3 2.0 1.7 1 0 0 1 1 1 1 Seripauperin and TIP1 family DDHD PF02862.12 CCD26304.1 - 0.022 14.5 5.9 0.027 14.2 4.1 1.3 1 0 0 1 1 1 0 DDHD domain CytochromB561_N PF09786.4 CCD26304.1 - 0.22 9.9 18.2 0.24 9.7 12.6 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DNA_pol_viral_N PF00242.12 CCD26304.1 - 0.23 10.4 13.4 0.25 10.3 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Macoilin PF09726.4 CCD26304.1 - 0.35 9.0 24.1 0.43 8.8 16.7 1.1 1 0 0 1 1 1 0 Transmembrane protein AhpC-TSA PF00578.16 CCD26305.1 - 1.4e-27 95.8 0.0 3e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCD26305.1 - 2.3e-18 66.1 0.0 4.3e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 CCD26305.1 - 0.058 13.3 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme Lipase_GDSL_3 PF14606.1 CCD26305.1 - 0.1 12.3 1.7 0.18 11.5 1.2 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family PglZ PF08665.7 CCD26305.1 - 0.27 10.8 2.3 0.51 9.9 1.6 1.5 1 0 0 1 1 1 0 PglZ domain CRAL_TRIO PF00650.15 CCD26306.1 - 3.2e-36 124.2 0.0 4.1e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CCD26306.1 - 0.0026 17.6 0.0 0.0036 17.2 0.0 1.3 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain X8 PF07983.8 CCD26306.1 - 0.078 13.4 0.6 17 5.9 0.1 2.3 2 0 0 2 2 2 0 X8 domain AAA PF00004.24 CCD26307.1 - 8.5e-11 42.1 0.0 2.5e-10 40.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CCD26307.1 - 1.8e-09 36.8 3.4 3.9e-05 22.5 0.0 3.3 3 1 0 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CCD26307.1 - 2.3e-05 25.2 0.1 9.1e-05 23.2 0.0 2.2 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CCD26307.1 - 3.8e-05 22.8 0.0 0.00016 20.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 CCD26307.1 - 0.00051 19.9 0.4 0.0021 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCD26307.1 - 0.00053 20.1 0.0 0.0051 16.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CCD26307.1 - 0.0012 18.8 0.0 0.0034 17.3 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 CCD26307.1 - 0.0032 17.3 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCD26307.1 - 0.0039 17.4 2.7 0.027 14.7 0.0 3.4 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 CCD26307.1 - 0.023 14.8 0.0 0.094 12.9 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 CCD26307.1 - 0.029 14.1 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain DUF258 PF03193.11 CCD26307.1 - 0.035 13.2 0.0 0.087 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IPT PF01745.11 CCD26307.1 - 0.06 12.5 0.1 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase IstB_IS21 PF01695.12 CCD26307.1 - 0.093 12.1 0.1 0.23 10.8 0.1 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 CCD26307.1 - 0.14 11.5 0.0 0.85 9.0 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_11 PF13086.1 CCD26307.1 - 2.8 7.4 13.6 1.8 8.0 5.7 2.8 2 1 0 2 2 2 0 AAA domain HEAT PF02985.17 CCD26308.1 - 3.8e-08 32.7 0.0 15 5.9 0.0 6.1 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 CCD26308.1 - 5.9e-05 23.2 0.0 0.05 13.8 0.0 4.6 5 1 1 6 6 6 1 HEAT repeats FANCI_S2 PF14676.1 CCD26308.1 - 0.011 15.6 4.3 0.25 11.2 0.1 4.1 3 0 0 3 3 3 0 FANCI solenoid 2 HEAT_EZ PF13513.1 CCD26308.1 - 0.041 14.3 0.1 8.1 7.0 0.0 4.3 5 0 0 5 5 5 0 HEAT-like repeat PHD PF00628.24 CCD26309.1 - 2.5e-13 49.4 20.5 1.6e-10 40.5 5.9 2.8 2 1 1 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.1 CCD26309.1 - 0.029 14.4 9.9 0.039 14.1 2.4 2.7 2 0 0 2 2 2 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 CCD26309.1 - 1.7 8.4 9.3 0.42 10.3 0.1 2.9 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 zf-BED PF02892.10 CCD26309.1 - 7.9 6.3 12.6 0.19 11.5 0.4 3.2 2 1 1 3 3 3 0 BED zinc finger dsDNA_bind PF01984.15 CCD26310.1 - 1.2e-28 99.2 0.9 1.5e-28 98.9 0.6 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Cyt-b5 PF00173.23 CCD26311.1 - 1.2e-17 63.4 0.0 1.9e-17 62.8 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF382 PF04037.8 CCD26311.1 - 0.096 12.5 0.6 2.3 8.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF382) HMG_box PF00505.14 CCD26312.1 - 3.4e-30 104.1 12.4 7.5e-15 54.9 2.0 2.2 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CCD26312.1 - 1.2e-21 76.8 9.3 4.7e-11 42.8 1.1 2.2 2 0 0 2 2 2 2 HMG-box domain DUF1299 PF06975.6 CCD26312.1 - 0.072 12.9 2.1 0.16 11.8 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1299) HMG_box_5 PF14887.1 CCD26312.1 - 0.28 11.0 6.2 0.12 12.1 0.2 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box 5 KRAB PF01352.22 CCD26312.1 - 1.3 8.5 8.4 0.93 9.0 1.0 2.8 3 0 0 3 3 3 0 KRAB box Imm35 PF15581.1 CCD26312.1 - 4 7.5 5.9 8.2 6.5 0.6 2.7 2 1 1 3 3 3 0 Immunity protein 35 Cg6151-P PF10233.4 CCD26313.1 - 2.2e-38 130.6 15.0 3.2e-38 130.1 10.4 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P ATG22 PF11700.3 CCD26313.1 - 0.68 8.3 11.3 1.3 7.4 7.8 1.3 1 1 0 1 1 1 0 Vacuole effluxer Atg22 like zf-C2H2 PF00096.21 CCD26314.1 - 7.3e-06 26.0 13.0 4.6e-05 23.5 2.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD26314.1 - 2.3e-05 24.3 12.4 0.00013 22.0 1.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 CCD26314.1 - 0.00052 20.0 1.5 0.0009 19.3 1.0 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CCD26314.1 - 0.0099 15.9 3.3 1.5 8.9 0.1 2.4 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) UPF0167 PF03691.9 CCD26314.1 - 0.092 12.1 0.1 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) zf-met PF12874.2 CCD26314.1 - 0.21 11.8 4.7 0.14 12.4 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 CCD26314.1 - 0.28 11.5 13.7 4.9 7.6 0.2 3.7 3 0 0 3 3 3 0 Zinc-finger double domain zf-BED PF02892.10 CCD26314.1 - 0.3 10.8 9.5 0.13 12.0 3.7 2.3 1 1 1 2 2 2 0 BED zinc finger NIF PF03031.13 CCD26316.1 - 1.9e-49 167.3 0.6 4.3e-49 166.2 0.1 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Mito_carr PF00153.22 CCD26317.1 - 9.4e-62 204.7 2.0 5.1e-22 77.3 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L14e PF01929.12 CCD26318.1 - 1.6e-31 108.4 0.6 2.4e-31 107.9 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CCD26318.1 - 1.7e-05 24.3 0.4 3.2e-05 23.4 0.3 1.5 1 0 0 1 1 1 1 KOW motif Oxysterol_BP PF01237.13 CCD26319.1 - 3.8e-94 315.0 0.1 4.9e-94 314.7 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein TRAM_LAG1_CLN8 PF03798.11 CCD26320.1 - 2.1e-34 118.8 27.7 2.1e-34 118.8 19.2 2.2 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CCD26320.1 - 1.6e-23 81.9 1.9 1.6e-23 81.9 1.3 2.0 2 0 0 2 2 2 1 TRAM1-like protein Herpes_LMP1 PF05297.6 CCD26320.1 - 0.57 9.0 7.8 0.98 8.2 5.4 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) PQ-loop PF04193.9 CCD26321.1 - 3.4e-12 45.7 13.4 4.1e-10 39.0 2.3 3.5 2 1 1 3 3 3 2 PQ loop repeat DUF765 PF05570.6 CCD26321.1 - 0.022 14.6 1.4 0.038 13.9 0.9 1.3 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF765) Herpes_UL95 PF03038.9 CCD26321.1 - 0.048 12.5 0.4 0.076 11.8 0.3 1.2 1 0 0 1 1 1 0 UL95 family ARD PF03079.9 CCD26322.1 - 2.6e-44 150.9 0.2 3e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 CCD26322.1 - 3.2e-10 39.3 0.0 6.4e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CCD26322.1 - 1.9e-06 27.5 0.0 2.6e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 CCD26322.1 - 5e-05 22.7 0.0 9.8e-05 21.8 0.0 1.5 2 0 0 2 2 2 1 Cupin Cupin_8 PF13621.1 CCD26322.1 - 0.0065 15.9 0.0 0.0075 15.7 0.0 1.3 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 CCD26322.1 - 0.098 12.9 0.0 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 JmjC domain, hydroxylase bZIP_1 PF00170.16 CCD26323.1 - 4.7e-07 29.6 5.5 4.7e-07 29.6 3.8 2.9 2 0 0 2 2 2 1 bZIP transcription factor Vac_Fusion PF02346.11 CCD26323.1 - 0.67 9.4 5.2 0.13 11.7 0.3 2.3 3 0 0 3 3 3 0 Chordopoxvirus fusion protein bZIP_2 PF07716.10 CCD26323.1 - 4.1 7.2 24.5 0.087 12.6 7.2 3.3 3 0 0 3 3 3 0 Basic region leucine zipper Rpr2 PF04032.11 CCD26325.1 - 1.2e-18 66.7 3.7 1.6e-18 66.3 2.6 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Proteasome PF00227.21 CCD26326.1 - 6.6e-56 188.6 0.0 8.7e-56 188.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCD26326.1 - 7.1e-14 50.8 0.1 1.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Helicase_C_3 PF13625.1 CCD26326.1 - 0.052 13.3 0.1 0.23 11.1 0.0 2.1 3 1 0 3 3 3 0 Helicase conserved C-terminal domain Hydantoinase_A PF01968.13 CCD26326.1 - 0.091 11.8 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase APC_CDC26 PF10471.4 CCD26326.1 - 1.2 9.9 7.6 2.6 8.8 5.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 RNase_P_Rpp14 PF01900.14 CCD26327.1 - 1.5e-30 105.2 0.0 2.1e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family SKIP_SNW PF02731.10 CCD26328.1 - 2.4e-38 131.0 1.2 2.4e-38 131.0 0.8 1.8 2 0 0 2 2 2 1 SKIP/SNW domain Cellulase PF00150.13 CCD26330.1 - 3.1e-15 56.1 0.3 1e-09 38.0 0.1 2.6 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 CCD26330.1 - 1.7e-05 24.3 0.2 3.7e-05 23.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.10 CCD26330.1 - 0.016 14.3 0.2 0.078 12.0 0.0 2.1 2 0 0 2 2 2 0 Beta-galactosidase DNA_primase_S PF01896.14 CCD26331.1 - 1.1e-53 180.9 0.6 2e-53 180.1 0.4 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit DUF2205 PF10224.4 CCD26331.1 - 0.42 10.2 4.2 0.15 11.6 0.8 1.8 2 0 0 2 2 2 0 Predicted coiled-coil protein (DUF2205) Zn_clus PF00172.13 CCD26332.1 - 2e-09 37.1 8.8 3.6e-09 36.3 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CCD26332.1 - 0.0067 15.3 2.2 0.11 11.3 0.0 2.7 2 0 0 2 2 2 2 Fungal specific transcription factor domain AMPKBI PF04739.10 CCD26334.1 - 7.4e-27 93.1 0.4 7.4e-27 93.1 0.3 3.2 3 1 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interation domain PAP1 PF08601.5 CCD26335.1 - 1.6e-09 37.9 37.5 1.6e-09 37.9 26.0 2.5 1 1 1 2 2 2 1 Transcription factor PAP1 APC_CDC26 PF10471.4 CCD26335.1 - 0.22 12.2 10.0 1.4 9.7 6.9 2.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Dynein_light PF01221.13 CCD26336.1 - 1.6e-33 114.5 0.0 1.9e-33 114.3 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 CCD26336.1 - 0.00012 22.3 0.0 0.00019 21.6 0.0 1.3 1 0 0 1 1 1 1 Ground-like domain DUF445 PF04286.7 CCD26336.1 - 0.1 12.0 0.1 0.11 11.9 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) DUF3646 PF12362.3 CCD26336.1 - 0.14 12.0 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal PCI PF01399.22 CCD26337.1 - 1.2e-14 54.4 0.6 1.2e-14 54.4 0.4 2.3 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CCD26337.1 - 0.003 17.3 1.9 0.0053 16.5 0.2 2.2 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 CCD26337.1 - 0.0048 16.4 0.4 0.0048 16.4 0.3 2.0 2 0 0 2 2 2 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Spo0A_C PF08769.6 CCD26337.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal DUF3901 PF13040.1 CCD26337.1 - 5 6.4 10.1 0.43 9.8 0.3 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3901) Spt5-NGN PF03439.8 CCD26338.1 - 2.6e-06 27.1 0.0 5.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 CCD26338.1 - 3.3e-05 23.4 0.1 8.4e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 KOW motif Pro_dh PF01619.13 CCD26339.1 - 2.1e-59 201.0 0.1 3.3e-59 200.4 0.1 1.2 1 0 0 1 1 1 1 Proline dehydrogenase M16C_assoc PF08367.6 CCD26340.1 - 7.8e-77 257.4 1.5 1.4e-76 256.6 1.1 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 CCD26340.1 - 1.2e-25 90.2 0.5 3.1e-13 49.7 0.0 4.1 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCD26340.1 - 1.3e-06 28.2 0.1 3.5e-05 23.5 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RRM_1 PF00076.17 CCD26341.1 - 5.7e-31 105.9 0.6 4e-18 64.8 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD26341.1 - 3.1e-18 65.5 0.0 1e-12 47.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD26341.1 - 7.5e-14 51.3 0.0 2.9e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.6 CCD26341.1 - 0.0068 16.3 0.0 0.015 15.2 0.0 1.5 2 0 0 2 2 2 1 RNA binding domain WWbp PF10349.4 CCD26341.1 - 0.0093 16.8 7.4 0.0093 16.8 5.2 4.7 2 2 2 4 4 4 1 WW-domain ligand protein PIG-S PF10510.4 CCD26342.1 - 2.8e-135 451.9 9.2 3.5e-135 451.6 6.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF1611 PF07755.6 CCD26342.1 - 0.00082 18.1 0.0 0.0013 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1611) TAFII28 PF04719.9 CCD26343.1 - 1.6e-27 95.0 0.3 1e-25 89.3 0.2 2.8 2 0 0 2 2 2 2 hTAFII28-like protein conserved region LCM PF04072.9 CCD26344.1 - 4.3e-20 72.0 0.0 6.2e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase SCP-1 PF05483.7 CCD26344.1 - 0.0043 14.9 0.1 0.0043 14.9 0.1 1.9 2 0 0 2 2 2 1 Synaptonemal complex protein 1 (SCP-1) PIG-P PF08510.7 CCD26345.1 - 6.7e-23 80.6 0.9 8.1e-23 80.4 0.6 1.1 1 0 0 1 1 1 1 PIG-P RRM_1 PF00076.17 CCD26346.1 - 0.00077 19.0 0.4 0.0018 17.8 0.3 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EamA PF00892.15 CCD26347.1 - 4.2e-08 33.2 3.4 4.2e-08 33.2 2.3 4.2 4 1 0 4 4 4 1 EamA-like transporter family TPT PF03151.11 CCD26347.1 - 7.3e-07 28.9 28.8 0.0016 18.0 6.3 3.4 2 2 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 CCD26347.1 - 1.4e-05 25.2 0.2 1.4e-05 25.2 0.2 3.6 4 1 0 4 4 4 1 Multidrug resistance efflux transporter DUF914 PF06027.7 CCD26347.1 - 0.00021 20.2 16.2 0.0053 15.6 6.6 3.3 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) DUF3180 PF11377.3 CCD26347.1 - 0.006 16.4 0.0 0.037 13.8 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF3180) UAA PF08449.6 CCD26347.1 - 0.0083 15.0 24.8 0.014 14.3 12.6 2.7 1 1 1 2 2 2 1 UAA transporter family DUF912 PF06024.7 CCD26347.1 - 0.094 12.7 0.2 0.094 12.7 0.1 4.3 4 1 1 5 5 5 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3302 PF11742.3 CCD26347.1 - 1.1 9.1 4.5 0.39 10.6 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) DUF1510 PF07423.6 CCD26347.1 - 1.7 7.9 8.4 0.43 9.9 0.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1510) MRAP PF15183.1 CCD26347.1 - 4.2 7.0 10.7 7.7 6.1 0.9 4.1 3 2 1 4 4 4 0 Melanocortin-2 receptor accessory protein family GATA PF00320.22 CCD26348.1 - 1.9e-10 39.9 6.8 4.9e-10 38.5 4.7 1.7 1 0 0 1 1 1 1 GATA zinc finger DOT1 PF08123.8 CCD26349.1 - 1.3e-84 282.5 0.1 2.8e-84 281.5 0.1 1.6 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 CCD26349.1 - 0.055 14.0 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Med13_C PF06333.7 CCD26350.1 - 5.5e-89 298.6 11.8 8.7e-59 199.1 0.3 3.7 3 1 1 4 4 4 2 Mediator complex subunit 13 C-terminal DUF676 PF05057.9 CCD26351.1 - 1.8e-48 164.7 0.0 2.8e-48 164.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CCD26351.1 - 6.8e-05 22.5 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 CCD26351.1 - 0.00068 18.8 0.1 0.0012 18.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) ECM11 PF15463.1 CCD26352.1 - 3.9e-31 108.2 0.1 3.9e-31 108.2 0.1 2.7 1 1 2 3 3 3 1 Extracellular mutant protein 11 Ribosomal_S17e PF00833.13 CCD26353.1 - 2.2e-56 188.8 0.2 2.6e-56 188.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 ZZ PF00569.12 CCD26354.1 - 3.8e-16 58.3 7.9 6.3e-16 57.6 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 CCD26354.1 - 1e-10 41.6 0.0 1.8e-08 34.3 0.0 2.8 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 CCD26354.1 - 1.8e-08 34.2 0.7 3.2e-08 33.4 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCD26354.1 - 0.00031 20.7 0.8 0.00069 19.6 0.0 2.0 2 1 1 3 3 3 1 Myb-like DNA-binding domain ARL2_Bind_BART PF11527.3 CCD26354.1 - 0.017 14.8 0.9 0.11 12.2 0.8 2.0 1 1 1 2 2 2 0 The ARF-like 2 binding protein BART U3_assoc_6 PF08640.6 CCD26355.1 - 6.5e-32 109.1 7.8 2.4e-31 107.3 1.3 3.1 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 CCD26355.1 - 5.3e-05 22.2 2.6 0.0016 17.3 0.7 2.7 1 1 1 2 2 2 2 NRDE-2, necessary for RNA interference Suf PF05843.9 CCD26355.1 - 0.00051 19.8 3.3 0.0043 16.8 2.3 2.4 1 1 0 1 1 1 1 Suppressor of forked protein (Suf) TPR_17 PF13431.1 CCD26355.1 - 0.014 15.5 0.7 5.6 7.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCD26355.1 - 0.05 14.2 0.0 8 7.4 0.0 2.9 1 1 2 3 3 3 0 Tetratricopeptide repeat Nuclease_act PF08133.6 CCD26355.1 - 0.081 12.4 0.7 0.36 10.3 0.0 2.3 2 0 0 2 2 2 0 Anticodon nuclease activator family Ribosomal_S13 PF00416.17 CCD26356.1 - 2.1e-42 143.8 1.9 2.5e-42 143.6 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CCD26356.1 - 0.0016 17.0 0.0 0.0027 16.3 0.0 1.3 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Metallophos PF00149.23 CCD26357.1 - 2.2e-11 43.5 0.7 5.1e-11 42.3 0.5 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AhpC-TSA PF00578.16 CCD26358.1 - 5.9e-34 116.4 0.0 1.6e-33 115.0 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CCD26358.1 - 5.9e-18 64.8 0.0 9.9e-18 64.0 0.0 1.3 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.4 CCD26358.1 - 2.5e-10 39.8 0.4 6.8e-10 38.4 0.1 1.9 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin Guanylate_kin PF00625.16 CCD26359.1 - 1.1e-70 236.8 0.0 1.2e-70 236.7 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 CCD26359.1 - 3.1e-07 30.3 0.0 9.2e-07 28.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCD26359.1 - 2.6e-06 27.5 0.0 9.3e-05 22.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCD26359.1 - 8.1e-06 26.6 0.1 1.8e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCD26359.1 - 1.1e-05 25.4 0.0 5.5e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CCD26359.1 - 1.2e-05 25.5 0.1 3.4e-05 24.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCD26359.1 - 3.6e-05 24.0 0.0 6.6e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.18 CCD26359.1 - 8.4e-05 22.5 0.1 0.00049 20.0 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 CCD26359.1 - 0.00012 22.0 0.0 0.00021 21.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain Miro PF08477.8 CCD26359.1 - 0.00029 21.3 0.0 0.00065 20.1 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 CCD26359.1 - 0.00037 19.7 0.0 0.00061 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CCD26359.1 - 0.00065 19.8 0.0 0.0029 17.7 0.0 2.0 2 1 0 2 2 2 1 RNA helicase AAA_24 PF13479.1 CCD26359.1 - 0.00071 19.2 0.4 0.018 14.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_10 PF12846.2 CCD26359.1 - 0.0009 18.7 0.1 0.0029 17.0 0.0 1.8 2 1 0 2 2 2 1 AAA-like domain Viral_helicase1 PF01443.13 CCD26359.1 - 0.0015 18.0 0.0 0.012 15.1 0.0 2.0 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 CCD26359.1 - 0.0016 18.1 0.1 0.0042 16.8 0.1 1.9 1 1 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 CCD26359.1 - 0.0018 17.9 0.0 0.0043 16.7 0.0 1.6 2 0 0 2 2 2 1 NACHT domain AAA_29 PF13555.1 CCD26359.1 - 0.0023 17.3 2.5 0.0075 15.7 0.1 2.4 2 1 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 CCD26359.1 - 0.0029 17.5 0.0 0.0067 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCD26359.1 - 0.0082 15.0 0.1 0.02 13.7 0.0 1.7 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF2075 PF09848.4 CCD26359.1 - 0.011 14.7 0.0 0.055 12.4 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 CCD26359.1 - 0.013 14.9 0.0 0.04 13.3 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 CCD26359.1 - 0.015 15.0 0.0 0.021 14.5 0.0 1.5 1 1 0 1 1 1 0 NTPase AAA PF00004.24 CCD26359.1 - 0.015 15.4 0.2 0.056 13.6 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 CCD26359.1 - 0.019 15.3 2.3 0.041 14.2 1.6 1.9 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 CCD26359.1 - 0.02 13.8 0.6 0.05 12.5 0.4 1.8 1 1 0 1 1 1 0 KAP family P-loop domain Thymidylate_kin PF02223.12 CCD26359.1 - 0.031 13.6 0.0 0.1 11.9 0.0 1.7 1 1 1 2 2 2 0 Thymidylate kinase Zeta_toxin PF06414.7 CCD26359.1 - 0.04 13.0 0.0 0.093 11.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Rad17 PF03215.10 CCD26359.1 - 0.042 12.5 0.0 0.057 12.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_2 PF07724.9 CCD26359.1 - 0.047 13.5 0.1 0.52 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_30 PF13604.1 CCD26359.1 - 0.049 13.2 0.0 0.088 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CCD26359.1 - 0.059 12.6 0.0 1.7 7.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_21 PF13304.1 CCD26359.1 - 0.062 13.2 0.5 0.1 12.5 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 CCD26359.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.1 CCD26359.1 - 0.078 12.7 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 CCD26359.1 - 0.099 12.2 0.1 0.22 11.1 0.0 1.7 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Na_H_Exchanger PF00999.16 CCD26360.1 - 1.1e-66 224.8 33.5 1.4e-66 224.5 23.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.1 CCD26360.1 - 0.09 12.3 4.1 0.11 12.1 0.9 2.2 2 0 0 2 2 2 0 Myc target protein 1 EVC2_like PF12297.3 CCD26360.1 - 1 7.9 6.3 1 7.9 1.4 2.4 1 1 1 2 2 2 0 Ellis van Creveld protein 2 like protein HECT PF00632.20 CCD26361.1 - 1.8e-95 319.7 1.0 5.7e-95 318.1 0.1 2.4 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 CCD26361.1 - 9.5e-61 205.9 3.4 9.5e-61 205.9 2.4 3.0 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 CCD26361.1 - 2.1e-44 151.8 1.2 6.9e-44 150.1 0.8 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 CCD26361.1 - 1.3e-17 63.6 0.9 4.9e-17 61.7 0.6 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) MSC PF09402.5 CCD26362.1 - 3.6e-77 259.3 5.3 3.6e-77 259.3 3.7 2.9 3 0 0 3 3 3 2 Man1-Src1p-C-terminal domain HeH PF12949.2 CCD26362.1 - 2.5e-16 58.9 0.9 9.1e-16 57.1 0.6 2.1 1 0 0 1 1 1 1 HeH/LEM domain zf-DHHC PF01529.15 CCD26363.1 - 1.1e-29 103.0 7.5 1.1e-29 103.0 5.2 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ly49 PF08391.5 CCD26363.1 - 0.04 14.0 0.2 0.04 14.0 0.2 2.1 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region COPIIcoated_ERV PF07970.7 CCD26364.1 - 7.5e-67 225.1 3.1 1e-66 224.7 2.2 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCD26364.1 - 6.6e-32 109.3 0.1 1.4e-31 108.2 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) GATA PF00320.22 CCD26365.1 - 1.8e-10 39.9 6.8 4.8e-10 38.5 4.7 1.7 1 0 0 1 1 1 1 GATA zinc finger KASH PF10541.4 CCD26365.1 - 1.2 9.0 4.7 1.3 8.8 0.2 2.3 2 0 0 2 2 2 0 Nuclear envelope localisation domain DUF3453 PF11935.3 CCD26366.1 - 2e-48 164.9 2.2 5.4e-48 163.4 0.5 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) GCV_H PF01597.14 CCD26367.1 - 1.5e-44 150.6 0.7 1.9e-44 150.2 0.5 1.2 1 0 0 1 1 1 1 Glycine cleavage H-protein BolA PF01722.13 CCD26368.1 - 5e-23 80.8 1.3 6.5e-23 80.4 0.9 1.2 1 0 0 1 1 1 1 BolA-like protein Mto2_bdg PF12808.2 CCD26369.1 - 1.7e-07 31.2 10.8 1.7e-07 31.2 7.5 3.8 3 0 0 3 3 3 1 Micro-tubular organiser Mto1 C-term Mto2-binding region MRG PF05712.8 CCD26370.1 - 5.8e-51 172.1 3.4 5.8e-51 172.1 2.4 1.8 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 CCD26370.1 - 4.3e-06 26.3 0.1 2.1e-05 24.0 0.0 2.3 2 1 0 2 2 2 1 RNA binding activity-knot of a chromodomain Orthopox_A5L PF06193.6 CCD26370.1 - 0.63 9.9 8.4 0.14 12.0 0.3 2.5 2 0 0 2 2 2 0 Orthopoxvirus A5L protein-like BolA PF01722.13 CCD26371.1 - 3.3e-16 58.9 0.0 4.8e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein DUF4140 PF13600.1 CCD26371.1 - 0.045 14.1 0.0 0.056 13.8 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF966 PF06136.8 CCD26371.1 - 0.048 13.0 0.3 0.049 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Dopey_N PF04118.9 CCD26371.1 - 0.082 11.6 0.3 0.11 11.2 0.2 1.1 1 0 0 1 1 1 0 Dopey, N-terminal Miro PF08477.8 CCD26372.1 - 3.4e-43 146.9 0.0 1.1e-20 74.2 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 CCD26372.1 - 6.1e-30 102.8 0.6 6.9e-29 99.4 0.0 2.7 3 0 0 3 3 2 1 EF hand associated EF_assoc_1 PF08355.7 CCD26372.1 - 6.2e-28 95.8 0.7 2.4e-27 94.0 0.7 1.9 2 0 0 2 2 2 1 EF hand associated Ras PF00071.17 CCD26372.1 - 1.6e-25 89.3 0.0 5.3e-12 45.4 0.0 2.6 2 1 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 CCD26372.1 - 7.6e-08 32.3 0.0 0.00071 19.5 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCD26372.1 - 1.1e-06 28.6 0.5 0.043 13.6 0.0 2.8 3 0 0 3 3 3 2 Dynamin family EF-hand_6 PF13405.1 CCD26372.1 - 1.3e-06 27.7 5.0 0.0002 20.9 0.0 4.0 4 0 0 4 4 3 1 EF-hand domain EF-hand_1 PF00036.27 CCD26372.1 - 3e-06 26.1 13.0 4e-05 22.6 0.3 3.8 5 0 0 5 5 4 2 EF hand EF-hand_8 PF13833.1 CCD26372.1 - 6.5e-06 25.6 1.2 0.0034 16.9 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 CCD26372.1 - 1e-05 25.5 6.3 0.0051 16.9 0.0 3.1 3 0 0 3 3 2 2 EF-hand domain pair Arf PF00025.16 CCD26372.1 - 1.8e-05 24.0 0.0 0.0012 18.1 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCD26372.1 - 0.00021 20.7 0.0 0.87 8.9 0.0 3.4 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain MobB PF03205.9 CCD26372.1 - 0.0003 20.4 0.2 0.2 11.3 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_5 PF13202.1 CCD26372.1 - 0.00039 19.6 7.0 0.00066 18.9 0.8 3.0 2 0 0 2 2 2 1 EF hand DUF258 PF03193.11 CCD26372.1 - 0.0009 18.4 0.1 0.052 12.7 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCD26372.1 - 0.0033 16.9 0.1 3.7 7.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RNA_helicase PF00910.17 CCD26372.1 - 0.0034 17.5 0.0 0.36 11.0 0.0 2.8 3 0 0 3 3 2 1 RNA helicase AAA_16 PF13191.1 CCD26372.1 - 0.005 16.8 0.0 0.32 10.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 CCD26372.1 - 0.0052 16.2 0.1 3.7 6.8 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain Septin PF00735.13 CCD26372.1 - 0.0063 15.5 0.0 1.1 8.2 0.0 2.3 2 0 0 2 2 2 1 Septin AAA_24 PF13479.1 CCD26372.1 - 0.0068 16.0 0.0 0.14 11.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 CCD26372.1 - 0.022 14.9 0.0 0.72 10.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCD26372.1 - 0.023 14.9 0.0 3 8.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 CCD26372.1 - 0.055 13.1 0.0 13 5.3 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase EF-hand_10 PF14788.1 CCD26372.1 - 0.53 9.9 3.9 3 7.5 0.0 2.9 3 0 0 3 3 2 0 EF hand Zn_clus PF00172.13 CCD26373.1 - 1.3e-09 37.7 10.6 2.9e-09 36.6 7.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRP PF06011.7 CCD26374.1 - 5.4e-156 519.5 37.5 5.4e-156 519.5 26.0 1.9 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCD26374.1 - 8.9e-43 145.7 2.2 8.9e-43 145.7 1.5 1.8 2 0 0 2 2 2 1 ML-like domain Neur_chan_memb PF02932.11 CCD26374.1 - 3e-05 24.0 1.6 0.0028 17.6 0.0 3.6 3 0 0 3 3 3 1 Neurotransmitter-gated ion-channel transmembrane region DUF1296 PF06972.6 CCD26374.1 - 0.022 14.6 0.4 0.056 13.4 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) DUF515 PF04415.7 CCD26374.1 - 0.43 8.7 12.7 0.87 7.7 8.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.4 CCD26374.1 - 3.3 7.1 20.0 7.2 6.0 13.9 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1635 PF07795.6 CCD26374.1 - 3.7 6.8 11.6 9.6 5.5 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1635) AMP-binding PF00501.23 CCD26375.1 - 2.5e-92 309.4 0.0 3.1e-92 309.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCD26375.1 - 3.4e-19 69.5 0.1 1.5e-18 67.5 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Kelch_4 PF13418.1 CCD26376.1 - 2.7e-09 36.6 13.1 8.5e-08 31.8 0.1 5.3 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 CCD26376.1 - 7.9e-09 35.4 0.1 0.00021 21.3 0.0 5.2 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_6 PF13964.1 CCD26376.1 - 1.2e-08 34.7 11.7 1.9e-05 24.6 0.2 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CCD26376.1 - 1.6e-06 27.6 9.1 0.0063 16.2 0.2 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.1 CCD26376.1 - 2.2e-06 27.5 10.4 0.88 9.6 0.0 6.7 6 1 0 6 6 6 3 Kelch motif Kelch_1 PF01344.20 CCD26376.1 - 6.9e-05 22.3 13.1 0.0022 17.4 0.7 4.8 5 0 0 5 5 5 2 Kelch motif Alb1 PF09135.6 CCD26377.1 - 2.8e-18 66.5 19.0 2.8e-18 66.5 13.2 2.2 1 1 1 2 2 2 1 Alb1 DUF948 PF06103.6 CCD26377.1 - 2.6 7.9 6.0 5.9 6.8 0.4 2.6 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) zf-C3HC PF07967.8 CCD26378.1 - 6.2e-08 32.4 0.5 1.8e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 C3HC zinc finger-like SR-25 PF10500.4 CCD26378.1 - 0.27 10.6 3.6 0.5 9.8 2.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ADH_N PF08240.7 CCD26379.1 - 5.4e-31 106.5 1.1 1e-30 105.6 0.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCD26379.1 - 8.2e-25 86.8 0.0 1.3e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 CCD26379.1 - 0.00048 20.2 0.0 0.00091 19.3 0.0 1.5 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 CCD26379.1 - 0.0077 16.3 0.1 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCD26379.1 - 0.0098 16.2 1.3 3.9 7.9 0.1 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 CCD26379.1 - 0.013 15.8 0.3 0.055 13.9 0.1 2.0 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pyr_redox_2 PF07992.9 CCD26379.1 - 0.091 12.6 0.3 0.27 11.0 0.2 1.9 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 CCD26379.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 CCD26379.1 - 0.11 12.5 0.3 0.32 11.0 0.2 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CCD26379.1 - 0.13 11.2 0.3 0.19 10.7 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain ADH_N PF08240.7 CCD26380.1 - 3.2e-34 116.9 2.4 6.3e-34 116.0 1.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCD26380.1 - 3.2e-23 81.6 0.0 5.5e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox PF00070.22 CCD26380.1 - 0.0028 18.0 0.1 0.029 14.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Prim_Zn_Ribbon PF08273.7 CCD26380.1 - 0.013 15.5 0.4 0.04 13.9 0.3 1.8 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase FAD_binding_3 PF01494.14 CCD26380.1 - 0.014 14.4 0.9 0.024 13.6 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain DAO PF01266.19 CCD26380.1 - 0.015 14.1 0.1 0.023 13.5 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ADH_zinc_N_2 PF13602.1 CCD26380.1 - 0.066 14.1 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 CCD26380.1 - 0.082 13.0 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 CCD26380.1 - 0.084 12.9 0.6 0.14 12.2 0.4 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 CCD26380.1 - 0.1 12.8 0.1 0.25 11.6 0.0 1.8 2 1 0 2 2 2 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.16 CCD26381.1 - 1.9e-77 260.1 5.8 2.4e-77 259.8 4.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CCD26381.1 - 2.5e-46 156.4 0.0 5.4e-46 155.4 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain BTB PF00651.26 CCD26382.1 - 2.3e-19 69.4 4.1 3.8e-10 39.7 0.1 3.0 3 1 0 3 3 3 2 BTB/POZ domain Ank PF00023.25 CCD26382.1 - 6e-10 38.4 0.1 2.1e-06 27.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CCD26382.1 - 8.5e-10 38.8 0.0 4.3e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCD26382.1 - 1.2e-08 35.1 0.0 3.6e-08 33.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCD26382.1 - 7.1e-06 25.7 0.1 0.018 15.2 0.0 3.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CCD26382.1 - 0.004 17.3 0.0 0.06 13.6 0.0 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Hormone_2 PF00123.15 CCD26382.1 - 0.53 10.1 4.1 0.13 12.1 0.4 1.9 2 0 0 2 2 2 0 Peptide hormone RRM_1 PF00076.17 CCD26383.1 - 5e-13 48.4 0.1 8.9e-13 47.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD26383.1 - 8.3e-11 41.7 0.1 1.3e-10 41.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD26383.1 - 3.8e-08 33.0 0.0 5.9e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop16 PF09420.5 CCD26384.1 - 6.3e-60 201.9 13.4 7.6e-60 201.7 9.3 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 PMI_typeI PF01238.16 CCD26385.1 - 4.8e-154 512.8 0.0 5.5e-154 512.6 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 CCD26385.1 - 6.6e-07 29.0 0.0 0.00066 19.3 0.0 2.5 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_2 PF07883.6 CCD26385.1 - 0.0047 16.3 0.0 2 7.9 0.0 2.6 2 0 0 2 2 2 2 Cupin domain UPF1_Zn_bind PF09416.5 CCD26386.1 - 2e-71 238.5 8.3 2e-71 238.5 5.8 2.5 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 CCD26386.1 - 2e-58 197.0 0.0 4.8e-58 195.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCD26386.1 - 1.5e-52 178.5 1.6 2.8e-52 177.6 1.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCD26386.1 - 2.3e-15 56.7 0.2 1.6e-13 50.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCD26386.1 - 8.5e-13 47.8 0.1 3e-12 46.0 0.2 1.9 2 0 0 2 2 1 1 Part of AAA domain UvrD-helicase PF00580.16 CCD26386.1 - 4.4e-06 26.2 0.6 0.021 14.1 0.1 3.1 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 CCD26386.1 - 1e-05 25.1 0.0 0.22 11.0 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 CCD26386.1 - 1.6e-05 24.0 0.1 0.00019 20.5 0.0 2.7 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CCD26386.1 - 2.5e-05 24.1 0.0 2.5e-05 24.1 0.0 2.5 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit PIF1 PF05970.9 CCD26386.1 - 0.00074 18.5 0.0 0.67 8.8 0.0 2.5 2 0 0 2 2 2 2 PIF1-like helicase Helicase_RecD PF05127.9 CCD26386.1 - 0.0041 16.7 0.0 0.0097 15.5 0.0 1.6 1 0 0 1 1 1 1 Helicase DEAD PF00270.24 CCD26386.1 - 0.0051 16.3 0.1 0.012 15.0 0.1 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 CCD26386.1 - 0.0052 16.0 0.0 0.013 14.7 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 CCD26386.1 - 0.017 14.0 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 CCD26386.1 - 0.048 13.6 1.7 0.059 13.3 0.2 1.8 2 0 0 2 2 1 0 AAA ATPase domain Ribosomal_S13_N PF08069.7 CCD26386.1 - 0.058 13.2 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain AAA_22 PF13401.1 CCD26386.1 - 0.1 12.7 0.3 0.28 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain UvrD_C_2 PF13538.1 CCD26386.1 - 0.14 12.3 0.1 0.99 9.5 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain KaiC PF06745.8 CCD26386.1 - 0.17 11.0 0.0 0.39 9.8 0.0 1.6 1 0 0 1 1 1 0 KaiC Phage_lysis PF03245.8 CCD26386.1 - 2.6 8.0 5.2 2.7 8.0 0.7 2.5 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein PIR PF00399.14 CCD26388.1 - 3.3e-07 29.4 8.3 1.5e-06 27.2 5.7 2.2 1 0 0 1 1 1 1 Yeast PIR protein repeat Peptidase_A22B PF04258.8 CCD26389.1 - 6.9e-52 176.7 8.8 6.9e-52 176.7 6.1 1.5 2 0 0 2 2 2 1 Signal peptide peptidase ADH_N PF08240.7 CCD26390.1 - 4.8e-31 106.7 0.7 9.9e-31 105.7 0.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCD26390.1 - 6.6e-29 100.0 0.4 1e-28 99.5 0.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCD26390.1 - 2.6e-05 25.1 0.1 7.1e-05 23.6 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Aminotran_1_2 PF00155.16 CCD26392.1 - 1.9e-30 106.0 0.0 2.4e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Macro_2 PF14519.1 CCD26393.1 - 1.6e-131 437.5 0.1 1.9e-131 437.3 0.1 1.0 1 0 0 1 1 1 1 Macro-like domain MFS_1 PF07690.11 CCD26394.1 - 3.1e-37 128.1 37.5 6.6e-35 120.4 25.5 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCD26394.1 - 8.3e-14 50.9 8.9 8.3e-14 50.9 6.2 2.9 2 1 1 3 3 3 1 Sugar (and other) transporter DUF3754 PF12576.3 CCD26394.1 - 0.28 10.8 1.8 0.34 10.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Peptidase_M41 PF01434.13 CCD26395.1 - 1.1e-72 244.0 1.1 1.4e-72 243.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 CCD26395.1 - 2.8e-42 144.0 0.0 5.8e-42 143.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CCD26395.1 - 1.2e-09 38.3 0.5 3e-09 37.0 0.3 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 CCD26395.1 - 0.00016 22.5 0.4 0.00054 20.7 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CCD26395.1 - 0.0011 18.7 0.6 0.14 12.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCD26395.1 - 0.0012 17.9 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CCD26395.1 - 0.0014 18.3 0.0 0.0057 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 CCD26395.1 - 0.0033 16.2 0.0 0.0061 15.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_2 PF07724.9 CCD26395.1 - 0.0037 17.2 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 CCD26395.1 - 0.0043 16.7 0.4 0.012 15.4 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CCD26395.1 - 0.0063 16.6 0.1 0.16 12.1 0.1 2.7 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCD26395.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 CCD26395.1 - 0.016 15.2 1.0 0.46 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CCD26395.1 - 0.031 14.2 0.2 0.14 12.1 0.1 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_25 PF13481.1 CCD26395.1 - 0.05 13.0 1.2 0.24 10.7 0.3 2.3 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 CCD26395.1 - 0.4 11.0 0.0 0.4 11.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain HSCB_C PF07743.8 CCD26395.1 - 1.6 9.2 7.5 24 5.4 1.6 4.1 4 0 0 4 4 4 0 HSCB C-terminal oligomerisation domain mRNA_stabil PF13929.1 CCD26396.1 - 8.6e-55 185.7 8.7 8.6e-55 185.7 6.0 1.9 2 0 0 2 2 2 1 mRNA stabilisation Oligomerisation PF02410.10 CCD26396.1 - 5.6e-11 42.3 0.2 1.5e-10 41.0 0.1 1.8 1 0 0 1 1 1 1 Oligomerisation domain Colicin_D PF11429.3 CCD26397.1 - 0.014 15.5 0.1 1.9 8.6 0.1 2.7 3 0 0 3 3 3 0 Colicin D UTP15_C PF09384.5 CCD26398.1 - 3.8e-51 172.6 0.6 5.7e-51 172.0 0.4 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CCD26398.1 - 1.6e-23 81.6 4.2 4.5e-06 26.3 0.0 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCD26398.1 - 0.00057 19.6 0.0 1.8 8.3 0.0 3.7 3 3 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 CCD26399.1 - 3.6e-30 102.7 20.8 0.00071 19.3 0.0 11.7 11 1 0 11 11 11 8 WD domain, G-beta repeat eIF2A PF08662.6 CCD26399.1 - 1.9e-09 37.5 0.8 0.001 18.8 0.0 3.8 2 1 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A CRC_subunit PF08624.5 CCD26400.1 - 1.6e-53 180.3 0.0 3.4e-53 179.2 0.0 1.6 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit NAD_binding_10 PF13460.1 CCD26401.1 - 7.9e-30 104.2 0.1 9.3e-30 103.9 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCD26401.1 - 2e-11 43.6 0.1 3e-11 43.0 0.1 1.3 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 CCD26401.1 - 3.7e-10 38.9 0.7 5.1e-10 38.5 0.5 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CCD26401.1 - 5.2e-06 26.7 0.1 9.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 CCD26401.1 - 5.3e-06 26.0 0.2 1.5e-05 24.5 0.1 1.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 CCD26401.1 - 1.8e-05 24.6 0.1 3.1e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 CCD26401.1 - 0.00057 18.9 0.2 0.00079 18.5 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Ldh_1_N PF00056.18 CCD26401.1 - 0.0011 18.8 0.3 0.0016 18.3 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CCD26401.1 - 0.011 16.1 1.4 0.015 15.7 0.1 1.9 3 0 0 3 3 2 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 CCD26401.1 - 0.019 15.4 0.0 0.037 14.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 CCD26401.1 - 0.092 12.7 0.6 0.14 12.1 0.4 1.4 1 0 0 1 1 1 0 TrkA-N domain BAF1_ABF1 PF04684.8 CCD26402.1 - 1.8e-84 284.3 14.2 2.3e-49 168.5 1.0 6.5 3 2 4 7 7 7 4 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.10 CCD26402.1 - 0.077 12.5 0.7 0.18 11.4 0.5 1.5 1 0 0 1 1 1 0 MuDR family transposase DUF3439 PF11921.3 CCD26402.1 - 9.2 6.0 9.1 1.2 8.8 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) XPG_N PF00752.12 CCD26403.1 - 1e-38 131.6 0.0 2.2e-38 130.5 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCD26403.1 - 3.7e-29 100.6 0.0 8.3e-29 99.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CCD26403.1 - 9e-07 29.0 0.1 8.1e-06 26.0 0.0 2.5 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold Phage_terminase PF10668.4 CCD26403.1 - 0.034 13.9 0.1 0.079 12.7 0.1 1.6 1 0 0 1 1 1 0 Phage terminase small subunit 5_3_exonuc_N PF02739.11 CCD26403.1 - 0.047 13.0 0.1 0.24 10.7 0.1 2.2 1 1 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Aldose_epim PF01263.15 CCD26404.1 - 1.7e-49 168.5 0.4 2.1e-49 168.2 0.3 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase zf-MYND PF01753.13 CCD26405.1 - 1.2e-06 28.2 22.2 2.9e-06 27.0 15.4 1.7 1 1 0 1 1 1 1 MYND finger Arm PF00514.18 CCD26405.1 - 0.0085 15.8 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat DUF1820 PF08850.6 CCD26405.1 - 0.093 12.8 0.2 0.19 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1820) Prenyltransf PF01255.14 CCD26406.1 - 4.8e-68 228.6 0.6 6.3e-68 228.2 0.4 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase SHP PF03579.8 CCD26406.1 - 1.2 8.4 7.4 0.062 12.6 0.9 1.9 2 0 0 2 2 2 0 Small hydrophobic protein WD40 PF00400.27 CCD26407.1 - 3.7e-18 64.6 25.6 2e-08 33.7 0.0 7.2 7 1 0 7 7 7 3 WD domain, G-beta repeat TF_Zn_Ribbon PF08271.7 CCD26407.1 - 0.0012 18.0 2.3 0.0033 16.6 1.6 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding BBS2_Mid PF14783.1 CCD26407.1 - 0.023 14.4 0.4 5.5 6.8 0.0 3.9 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.20 CCD26408.1 - 4.9e-70 235.6 0.0 9.1e-70 234.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26408.1 - 4e-31 108.0 0.0 6e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCD26408.1 - 3.7e-09 36.9 0.3 1.1e-08 35.5 0.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCD26408.1 - 0.00073 18.5 0.0 0.0016 17.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCD26408.1 - 0.049 12.6 0.1 0.1 11.6 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD26408.1 - 0.12 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Macoilin PF09726.4 CCD26408.1 - 9.7 4.3 12.7 14 3.8 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein PGM_PMM_I PF02878.11 CCD26409.1 - 2.1e-36 124.4 0.8 9.6e-36 122.3 0.1 2.1 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CCD26409.1 - 1.8e-23 82.7 0.0 3.2e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CCD26409.1 - 7.7e-14 51.8 0.0 1.7e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCD26409.1 - 1.4e-08 34.6 0.0 3.1e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ku PF02735.11 CCD26410.1 - 7.3e-34 116.9 0.1 1.6e-33 115.8 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CCD26410.1 - 3.8e-17 62.4 0.3 6.2e-17 61.7 0.2 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain TP6A_N PF04406.9 CCD26411.1 - 1.1e-11 44.2 1.0 2.4e-11 43.1 0.7 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase TPP_enzyme_N PF02776.13 CCD26412.1 - 2.6e-57 193.0 1.4 7.5e-57 191.5 0.1 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCD26412.1 - 5.4e-50 168.9 0.1 3.6e-49 166.2 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCD26412.1 - 1.5e-37 128.4 1.2 5.8e-37 126.5 0.1 2.4 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain POR_N PF01855.14 CCD26412.1 - 0.073 12.5 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg CO_dh PF02552.11 CCD26412.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit Aldedh PF00171.17 CCD26413.1 - 7.3e-78 261.9 0.0 8.8e-78 261.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cys_Met_Meta_PP PF01053.15 CCD26414.1 - 3e-145 483.3 0.0 3.4e-145 483.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 CCD26414.1 - 2.2e-05 22.9 0.0 3.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 CCD26414.1 - 0.00021 20.3 0.1 0.0003 19.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.11 CCD26414.1 - 0.022 13.4 0.0 0.032 12.9 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Aminotran_5 PF00266.14 CCD26414.1 - 0.05 12.3 0.0 0.094 11.4 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCD26414.1 - 0.11 11.6 0.0 0.28 10.3 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CCD26414.1 - 0.12 11.4 0.0 0.36 9.8 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_S19 PF00203.16 CCD26415.1 - 1.9e-32 110.6 0.1 3.7e-32 109.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S19 FliH PF02108.11 CCD26415.1 - 0.069 13.0 0.0 0.085 12.7 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH Sds3 PF08598.6 CCD26416.1 - 4.2e-41 140.7 2.0 4.2e-41 140.7 1.4 3.5 2 1 0 2 2 2 1 Sds3-like Grp1_Fun34_YaaH PF01184.14 CCD26417.1 - 8.8e-89 296.3 10.6 1e-88 296.1 7.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF373 PF04123.8 CCD26417.1 - 0.42 9.5 3.6 0.47 9.4 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF373) SNARE PF05739.14 CCD26418.1 - 3.2e-10 39.5 1.9 1.2e-09 37.7 1.3 2.1 1 0 0 1 1 1 1 SNARE domain DUF1682 PF07946.9 CCD26418.1 - 0.031 13.1 4.6 0.078 11.8 3.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) TBCA PF02970.11 CCD26418.1 - 0.88 9.6 7.5 11 6.1 0.2 3.9 4 1 1 5 5 5 0 Tubulin binding cofactor A HhH-GPD PF00730.20 CCD26419.1 - 1.1e-21 77.1 0.0 3.2e-21 75.6 0.0 1.7 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CCD26419.1 - 1.2e-06 27.9 0.0 4.4e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HEAT PF02985.17 CCD26420.1 - 9.3e-41 134.2 16.9 0.0011 18.9 0.1 13.2 13 0 0 13 13 13 9 HEAT repeat HEAT_2 PF13646.1 CCD26420.1 - 2.5e-30 104.5 0.0 1.6e-08 34.7 0.0 7.8 2 2 5 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.2 CCD26420.1 - 1.6e-14 54.0 3.2 0.00036 20.8 0.0 8.5 4 2 5 9 9 9 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCD26420.1 - 3e-08 33.8 13.4 1.4 9.5 0.0 9.3 10 1 1 11 11 11 3 HEAT-like repeat M11L PF11099.3 CCD26420.1 - 0.0047 16.6 7.2 0.24 11.1 0.1 3.3 1 1 1 3 3 3 2 Apoptosis regulator M11L like GatB_Yqey PF02637.13 CCD26420.1 - 0.019 14.7 0.5 6.8 6.3 0.0 2.7 2 0 0 2 2 2 0 GatB domain Ecm29 PF13001.2 CCD26420.1 - 0.024 13.1 3.2 0.15 10.5 0.2 2.8 3 0 0 3 3 3 0 Proteasome stabiliser DUF2454 PF10521.4 CCD26420.1 - 0.072 12.0 7.0 0.31 9.9 0.1 4.2 5 0 0 5 5 5 0 Protein of unknown function (DUF2454) Pkinase PF00069.20 CCD26421.1 - 1.1e-63 214.8 0.1 2.8e-63 213.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26421.1 - 1.6e-23 83.1 0.0 2.7e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD26421.1 - 1.2e-10 40.8 0.0 2.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCD26421.1 - 0.0024 17.6 0.0 0.0064 16.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family PAS_9 PF13426.1 CCD26421.1 - 0.0084 16.4 0.0 1.3 9.4 0.0 2.8 2 0 0 2 2 2 1 PAS domain Kdo PF06293.9 CCD26421.1 - 0.021 13.8 0.1 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Med15_fungi PF05397.7 CCD26423.1 - 1.9e-38 130.9 3.2 1.9e-38 130.9 2.2 6.8 3 1 1 6 6 6 1 Mediator complex subunit 15 SNF2_N PF00176.18 CCD26424.1 - 3.5e-67 226.3 1.3 9.4e-67 224.9 0.3 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCD26424.1 - 3.7e-15 55.5 0.0 2.5e-13 49.6 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RNA_pol_3_Rpc31 PF11705.3 CCD26424.1 - 0.00031 20.7 7.1 0.00031 20.7 4.9 3.6 3 0 0 3 3 3 1 DNA-directed RNA polymerase III subunit Rpc31 AAA_22 PF13401.1 CCD26424.1 - 0.027 14.5 0.0 0.092 12.8 0.0 1.9 1 0 0 1 1 1 0 AAA domain ER-remodelling PF14755.1 CCD26424.1 - 0.17 11.9 3.0 0.46 10.5 2.1 1.7 1 0 0 1 1 1 0 Intracellular membrane remodeller RCC1_2 PF13540.1 CCD26425.1 - 2.9e-12 45.8 14.6 3.6e-06 26.4 0.7 5.1 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CCD26425.1 - 3.6e-12 46.2 7.9 0.17 12.0 0.0 6.3 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Exo_endo_phos PF03372.18 CCD26426.1 - 4e-23 82.6 0.1 6.3e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CCD26426.1 - 1.7e-13 49.8 13.9 7.5e-10 38.2 3.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCD26426.1 - 1e-07 31.5 4.3 1e-07 31.5 2.9 3.7 4 1 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.28 CCD26426.1 - 2.1e-05 23.9 23.7 0.015 15.2 0.5 6.3 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 CCD26426.1 - 0.095 12.9 27.2 0.14 12.4 1.5 6.3 6 0 0 6 6 6 0 Leucine rich repeat Nucleoside_tran PF01733.13 CCD26427.1 - 5e-58 196.7 24.2 1.3e-42 146.0 5.4 2.6 2 1 1 3 3 3 2 Nucleoside transporter PMT PF02366.13 CCD26428.1 - 1.1e-92 309.8 18.0 1.1e-92 309.8 12.5 2.0 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCD26428.1 - 2.7e-28 98.7 0.3 6.2e-28 97.6 0.2 1.6 1 0 0 1 1 1 1 MIR domain RasGEF PF00617.14 CCD26429.1 - 5.9e-42 143.5 0.9 1.4e-41 142.2 0.6 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCD26429.1 - 8.2e-12 45.1 0.5 8.2e-12 45.1 0.3 3.4 3 0 0 3 3 3 1 RasGEF N-terminal motif E1-E2_ATPase PF00122.15 CCD26430.1 - 1.2e-17 63.7 0.9 2.2e-17 62.8 0.6 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CCD26430.1 - 2.7e-16 60.2 0.1 7.3e-16 58.9 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCD26430.1 - 4.1e-13 50.2 1.2 6e-10 39.8 0.9 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCD26430.1 - 1.2e-10 41.1 0.0 5.6e-10 39.0 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCD26430.1 - 9.3e-05 22.1 1.6 0.026 14.1 0.1 2.8 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Saw1 PF11561.3 CCD26431.1 - 3e-48 164.0 10.4 3.5e-48 163.8 7.2 1.0 1 0 0 1 1 1 1 Single strand annealing-weakened 1 Hph PF13694.1 CCD26432.1 - 3e-10 40.4 14.1 3e-10 40.4 9.8 4.7 3 3 1 4 4 4 1 Sec63/Sec62 complex-interacting family Myosin_head PF00063.16 CCD26433.1 - 1.3e-249 829.8 14.1 2.7e-249 828.8 9.8 1.5 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 CCD26433.1 - 4.7e-23 81.0 3.3 4.7e-23 81.0 2.3 3.7 4 1 1 5 5 5 1 DIL domain IQ PF00612.22 CCD26433.1 - 1e-05 24.6 16.8 0.56 10.0 0.8 6.5 6 0 0 6 6 6 3 IQ calmodulin-binding motif AAA_22 PF13401.1 CCD26433.1 - 0.0022 18.1 1.8 0.015 15.4 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.22 CCD26433.1 - 0.017 15.4 0.1 0.017 15.4 0.0 3.1 2 1 0 2 2 2 0 ABC transporter Myosin_N PF02736.14 CCD26433.1 - 0.033 13.8 0.7 0.079 12.6 0.1 1.9 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain AAA_16 PF13191.1 CCD26433.1 - 0.075 13.0 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 CCD26433.1 - 0.16 11.7 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain vATP-synt_E PF01991.13 CCD26434.1 - 9.6e-59 197.9 16.6 1.1e-58 197.7 11.5 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4162 PF13732.1 CCD26434.1 - 0.0094 16.4 10.4 0.12 12.9 3.6 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4162) FANCI_S2 PF14676.1 CCD26434.1 - 0.022 14.6 0.7 0.034 14.0 0.5 1.3 1 0 0 1 1 1 0 FANCI solenoid 2 tRNA-synt_2e PF02091.10 CCD26434.1 - 0.062 12.3 1.3 0.079 12.0 0.9 1.2 1 0 0 1 1 1 0 Glycyl-tRNA synthetase alpha subunit Phlebovirus_NSM PF07246.6 CCD26434.1 - 0.11 11.6 10.4 0.09 11.9 6.2 1.4 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M EMP24_GP25L PF01105.19 CCD26436.1 - 1.4e-34 119.3 0.8 1.4e-34 119.3 0.5 1.5 2 0 0 2 2 2 1 emp24/gp25L/p24 family/GOLD Cystatin PF00031.16 CCD26436.1 - 0.1 12.7 0.1 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 Cystatin domain FUN14 PF04930.10 CCD26437.1 - 0.00051 20.2 6.8 0.00074 19.7 3.3 2.2 2 1 0 2 2 2 1 FUN14 family DUF4296 PF14129.1 CCD26437.1 - 0.12 12.4 0.1 14 5.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) Peptidase_A2B PF12384.3 CCD26438.1 - 0.024 13.9 0.0 0.036 13.3 0.0 1.3 1 0 0 1 1 1 0 Ty3 transposon peptidase MCR_alpha_N PF02745.10 CCD26438.1 - 0.063 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Spo7 PF03907.8 CCD26439.1 - 2.6e-79 265.6 5.6 3.3e-79 265.3 3.9 1.1 1 0 0 1 1 1 1 Spo7-like protein DUF2208 PF09973.4 CCD26439.1 - 0.002 17.3 0.8 0.019 14.1 0.0 2.0 1 1 1 2 2 2 1 Predicted membrane protein (DUF2208) ABC2_membrane_4 PF12730.2 CCD26439.1 - 0.05 12.7 1.6 0.073 12.2 1.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4538 PF15061.1 CCD26439.1 - 0.11 11.8 0.3 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4538) DUF3722 PF12519.3 CCD26440.1 - 7.3e-68 228.6 17.1 7.3e-68 228.6 11.8 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3722) DUF999 PF06198.6 CCD26440.1 - 2.2 8.0 6.9 1.9 8.2 0.3 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF999) DUF2368 PF10166.4 CCD26441.1 - 3.8 7.1 9.5 1.8 8.1 4.8 1.8 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) GCR1_C PF12550.3 CCD26442.1 - 9.5e-23 79.8 0.6 2.1e-22 78.7 0.4 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF159 PF02586.9 CCD26443.1 - 3.1e-54 183.6 0.3 4.4e-54 183.1 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 TACC PF05010.9 CCD26444.1 - 0.00031 20.5 0.0 0.00061 19.6 0.0 1.5 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC) SNAP PF14938.1 CCD26444.1 - 0.0027 16.8 7.2 0.17 11.0 1.1 2.2 2 0 0 2 2 2 2 Soluble NSF attachment protein, SNAP DUF3498 PF12004.3 CCD26444.1 - 0.029 13.5 0.4 0.044 12.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) TPR_12 PF13424.1 CCD26444.1 - 0.15 12.0 7.1 2.2 8.2 0.1 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCD26444.1 - 0.15 11.9 0.6 6.3 6.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Cep57_CLD_2 PF14197.1 CCD26444.1 - 0.36 10.7 4.4 2.3 8.1 2.0 2.9 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 WD40 PF00400.27 CCD26445.1 - 6.9e-55 181.0 10.6 9.8e-09 34.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CCD26445.1 - 3.5e-05 23.6 0.7 0.0061 16.2 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCD26445.1 - 0.00013 20.2 7.8 0.13 10.3 0.1 4.2 1 1 4 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCD26445.1 - 0.003 16.3 0.5 0.85 8.2 0.3 3.2 2 2 1 3 3 3 2 Nup133 N terminal like Spc24 PF08286.6 CCD26446.1 - 2e-16 59.7 8.5 2e-16 59.7 5.9 3.2 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 Tup_N PF08581.5 CCD26446.1 - 0.00011 22.3 5.8 0.00017 21.6 0.5 2.5 2 0 0 2 2 2 1 Tup N-terminal Allexi_40kDa PF05549.6 CCD26446.1 - 0.0043 16.3 6.2 0.0067 15.7 4.3 1.2 1 0 0 1 1 1 1 Allexivirus 40kDa protein OmpH PF03938.9 CCD26446.1 - 0.078 12.9 2.7 0.12 12.2 1.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Lzipper-MIP1 PF14389.1 CCD26446.1 - 0.15 12.2 6.5 0.89 9.7 4.5 2.2 1 1 1 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF489 PF04356.7 CCD26446.1 - 0.16 11.5 1.8 0.25 10.9 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) APG6 PF04111.7 CCD26446.1 - 0.17 10.8 9.5 0.26 10.2 6.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 LMBR1 PF04791.11 CCD26446.1 - 0.26 9.8 2.6 0.29 9.6 1.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Seryl_tRNA_N PF02403.17 CCD26446.1 - 0.36 10.8 14.2 0.94 9.5 8.7 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain IncA PF04156.9 CCD26446.1 - 0.36 10.3 6.7 0.53 9.8 4.6 1.3 1 0 0 1 1 1 0 IncA protein DUF3552 PF12072.3 CCD26446.1 - 0.48 9.5 10.2 0.72 9.0 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) YrzO PF14142.1 CCD26446.1 - 0.88 9.2 5.2 2.3 7.8 0.2 2.8 2 1 1 3 3 3 0 YrzO-like protein V_ATPase_I PF01496.14 CCD26446.1 - 0.89 7.3 4.3 1.2 6.9 3.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 CCD26446.1 - 1.7 8.9 10.5 0.74 10.1 2.3 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.8 CCD26446.1 - 1.8 7.5 6.7 2.5 7.0 4.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF2730 PF10805.3 CCD26446.1 - 1.9 8.2 5.5 3.7 7.3 1.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Synaptobrevin PF00957.16 CCD26446.1 - 2.3 7.8 7.6 7.2 6.2 0.5 2.6 2 1 0 2 2 2 0 Synaptobrevin Bap31 PF05529.7 CCD26446.1 - 3.5 7.0 8.0 10 5.5 5.1 2.1 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like Viral_P18 PF04521.8 CCD26446.1 - 3.7 7.0 5.2 8 5.9 0.4 2.3 1 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein SlyX PF04102.7 CCD26446.1 - 3.8 7.9 6.2 52 4.3 0.1 3.6 2 1 3 5 5 5 0 SlyX CCDC-167 PF15188.1 CCD26446.1 - 7.3 6.6 9.4 36 4.3 0.0 2.6 2 1 0 2 2 2 0 Coiled-coil domain-containing protein 167 DUF1664 PF07889.7 CCD26446.1 - 8.4 6.2 8.2 43 3.9 5.5 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) zf-C3HC4_3 PF13920.1 CCD26447.1 - 7.8e-09 35.0 12.1 7.8e-09 35.0 8.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) VESA1_N PF12785.2 CCD26447.1 - 0.049 12.5 13.5 0.044 12.7 8.1 1.7 2 0 0 2 2 2 0 Variant erythrocyte surface antigen-1 AICARFT_IMPCHas PF01808.13 CCD26448.1 - 1.5e-120 402.0 0.0 1.9e-120 401.7 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CCD26448.1 - 4.2e-24 84.2 0.3 1.9e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 MGS-like domain CAF1C_H4-bd PF12265.3 CCD26449.1 - 2e-19 69.2 0.1 4.5e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 CCD26449.1 - 1.3e-18 66.1 9.2 1.5e-06 27.8 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat HAD_2 PF13419.1 CCD26450.1 - 2.7e-21 76.5 0.0 3.9e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCD26450.1 - 7.8e-08 31.9 0.0 1.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCD26450.1 - 1.8e-05 25.2 0.0 8.7e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase MOZ_SAS PF01853.13 CCD26452.1 - 1e-64 217.2 0.8 2e-64 216.3 0.6 1.5 1 0 0 1 1 1 1 MOZ/SAS family TLP-20 PF06088.6 CCD26452.1 - 0.031 13.9 5.6 0.12 12.0 1.9 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) AF1Q PF15017.1 CCD26452.1 - 0.033 14.0 3.7 0.065 13.1 2.6 1.5 1 0 0 1 1 1 0 Drug resistance and apoptosis regulator Prothymosin PF03247.9 CCD26452.1 - 0.039 14.0 14.6 0.069 13.3 10.1 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Ribosomal_60s PF00428.14 CCD26452.1 - 0.091 13.1 5.1 0.17 12.3 3.5 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-C2H2 PF00096.21 CCD26452.1 - 0.21 12.0 3.2 0.16 12.3 0.8 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type CopD PF05425.8 CCD26453.1 - 0.13 12.4 0.5 0.2 11.8 0.3 1.2 1 0 0 1 1 1 0 Copper resistance protein D TT_ORF1 PF02956.9 CCD26453.1 - 2.1 6.7 11.9 2.6 6.4 7.8 1.3 1 1 0 1 1 1 0 TT viral orf 1 MIF4G_like PF09088.6 CCD26454.1 - 1.6e-60 203.8 1.2 6.4e-60 201.8 0.9 2.0 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 CCD26454.1 - 6.9e-44 149.9 6.1 6.9e-44 149.9 4.2 2.5 3 0 0 3 3 3 1 MIF4G like Pkr1 PF08636.5 CCD26457.1 - 5.7e-32 109.5 9.7 7.1e-32 109.2 6.7 1.1 1 0 0 1 1 1 1 ER protein Pkr1 O-antigen_lig PF13425.1 CCD26457.1 - 0.0034 17.3 0.0 0.0038 17.2 0.0 1.1 1 0 0 1 1 1 1 O-antigen ligase like membrane protein PAP2 PF01569.16 CCD26457.1 - 0.036 13.7 3.4 0.066 12.8 1.9 1.7 2 0 0 2 2 2 0 PAP2 superfamily Kei1 PF08552.6 CCD26457.1 - 0.075 12.6 1.1 0.2 11.2 0.9 1.7 1 1 1 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4191 PF13829.1 CCD26457.1 - 0.11 11.5 0.0 0.13 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF814 PF05670.8 CCD26459.1 - 2.1e-19 69.2 0.8 2.7e-19 68.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF814) Meiotic_rec114 PF03525.9 CCD26460.1 - 4.2e-12 45.2 20.1 1.3e-11 43.6 13.9 2.0 1 1 0 1 1 1 1 Meiotic recombination protein rec114 CLTH PF10607.4 CCD26462.1 - 3.7e-22 78.5 12.5 9.5e-22 77.2 6.7 2.6 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain GATA PF00320.22 CCD26463.1 - 3.8e-16 58.1 2.8 1e-15 56.7 1.9 1.7 1 0 0 1 1 1 1 GATA zinc finger UreF PF01730.11 CCD26463.1 - 6.6 6.8 7.6 0.2 11.7 0.4 1.9 2 0 0 2 2 2 0 UreF DRMBL PF07522.9 CCD26464.1 - 3.7e-23 81.6 0.1 3.7e-23 81.6 0.1 3.0 3 1 0 3 3 3 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CCD26464.1 - 5.6e-11 42.3 0.1 1.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Arf PF00025.16 CCD26465.1 - 2.3e-37 127.9 0.5 6.3e-34 116.7 0.4 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 CCD26465.1 - 1.8e-15 56.5 7.2 3.4e-09 35.8 0.1 2.9 2 1 1 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.18 CCD26465.1 - 2.3e-08 34.0 0.0 3.1e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CCD26465.1 - 1.4e-06 27.8 0.0 0.0001 21.7 0.0 2.4 2 0 0 2 2 2 1 Ras family GTP_EFTU PF00009.22 CCD26465.1 - 1.9e-06 27.4 0.0 0.0021 17.5 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCD26465.1 - 4.6e-05 22.6 0.0 0.00035 19.7 0.0 2.1 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCD26465.1 - 0.00041 20.8 0.0 0.00071 20.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein DAP3 PF10236.4 CCD26465.1 - 0.0054 15.7 0.1 0.0066 15.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 SRPRB PF09439.5 CCD26465.1 - 0.0073 15.5 0.0 0.013 14.6 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 CCD26465.1 - 0.025 13.8 0.2 1 8.6 0.0 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B Bd3614-deam PF14439.1 CCD26465.1 - 0.078 12.8 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase AAA_29 PF13555.1 CCD26465.1 - 0.1 12.1 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pkinase PF00069.20 CCD26466.1 - 5.4e-59 199.4 0.1 1e-58 198.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26466.1 - 2.3e-24 85.8 0.0 4.3e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCD26466.1 - 0.0026 17.5 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCD26466.1 - 3.5 7.1 10.8 0.032 13.7 0.5 2.5 3 0 0 3 3 3 0 Choline/ethanolamine kinase ADH_N PF08240.7 CCD26467.1 - 1.4e-27 95.6 4.9 2.7e-27 94.6 3.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCD26467.1 - 1.6e-16 60.0 0.0 4.9e-16 58.4 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCD26467.1 - 2.8e-05 23.3 0.3 5e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CCD26467.1 - 0.029 13.9 0.0 0.08 12.5 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ADH_N PF08240.7 CCD26468.1 - 5.1e-29 100.2 3.9 1.1e-28 99.1 2.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCD26468.1 - 6.1e-16 58.1 0.0 9.6e-16 57.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCD26468.1 - 0.00023 20.3 0.1 0.00045 19.4 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 CCD26469.1 - 7.3e-65 218.5 0.0 8.3e-65 218.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family zf-C3HC4_2 PF13923.1 CCD26470.1 - 1.6 8.7 8.3 10 6.2 5.8 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L13e PF01294.13 CCD26471.1 - 1.1e-72 243.2 5.1 1.5e-72 242.8 3.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e 4HBT_3 PF13622.1 CCD26471.1 - 0.067 12.9 0.3 0.088 12.5 0.2 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Ribosomal_S9 PF00380.14 CCD26472.1 - 8.7e-39 132.5 0.2 9.9e-39 132.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Glyco_trans_1_3 PF13528.1 CCD26472.1 - 0.076 12.1 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 Nckap1 PF09735.4 CCD26472.1 - 0.15 9.5 0.0 0.17 9.2 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein Imm36 PF15597.1 CCD26473.1 - 0.006 16.7 1.8 0.018 15.1 1.2 1.9 1 0 0 1 1 1 1 Immunity protein 36 Pyr_redox_2 PF07992.9 CCD26474.1 - 3.5e-28 98.8 0.1 1.4e-18 67.5 0.0 3.5 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCD26474.1 - 1.2e-11 44.7 0.1 3.2e-10 40.2 0.4 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCD26474.1 - 8.9e-07 29.1 0.0 0.0059 16.6 0.0 3.4 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase 4F5 PF04419.9 CCD26475.1 - 3e-09 37.4 11.5 3e-09 37.4 8.0 2.2 2 0 0 2 2 2 1 4F5 protein family Vac_Fusion PF02346.11 CCD26475.1 - 0.015 14.7 0.0 0.023 14.1 0.0 1.4 1 1 0 1 1 1 0 Chordopoxvirus fusion protein DDRGK PF09756.4 CCD26475.1 - 2.3 7.5 12.8 2.5 7.4 8.8 1.0 1 0 0 1 1 1 0 DDRGK domain DUF1423 PF07227.6 CCD26475.1 - 3 6.4 6.9 2.9 6.4 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1423) WD40 PF00400.27 CCD26476.1 - 1.9e-28 97.2 4.5 1.4e-08 34.2 0.4 5.6 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CCD26476.1 - 0.00018 21.3 0.4 0.44 10.2 0.1 3.3 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CCD26476.1 - 0.0034 16.1 0.8 0.29 9.8 0.0 2.2 2 0 0 2 2 2 2 Nup133 N terminal like Sigma70_ner PF04546.8 CCD26477.1 - 0.0091 15.6 11.1 0.015 14.9 7.7 1.4 1 0 0 1 1 1 1 Sigma-70, non-essential region Nucleoplasmin PF03066.10 CCD26477.1 - 1.1 8.7 13.4 2.1 7.8 9.3 1.6 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 CCD26477.1 - 1.2 7.0 11.9 1.5 6.8 8.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 CCD26477.1 - 2.4 6.5 19.4 2.7 6.3 13.4 1.1 1 0 0 1 1 1 0 Daxx Family DUF1840 PF08895.6 CCD26477.1 - 2.4 8.2 4.7 23 5.0 0.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1840) NOA36 PF06524.7 CCD26477.1 - 2.8 7.0 9.8 4.1 6.5 6.8 1.4 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 CCD26477.1 - 3 6.4 18.5 3.7 6.1 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRN3 PF05327.6 CCD26477.1 - 3.9 5.4 12.9 5.1 5.0 8.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sporozoite_P67 PF05642.6 CCD26477.1 - 4.9 4.8 7.1 6.1 4.5 4.9 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Pox_RNA_Pol_19 PF05320.7 CCD26477.1 - 5.4 6.7 17.4 2.1 8.0 9.5 2.1 1 1 1 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit EI24 PF07264.6 CCD26478.1 - 0.081 12.3 3.7 0.11 11.9 2.6 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF2207 PF09972.4 CCD26478.1 - 0.12 10.9 2.7 0.062 11.8 0.6 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Ribophorin_II PF05817.9 CCD26479.1 - 2.4e-09 36.0 0.7 3.6e-09 35.4 0.5 1.3 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Peptidase_S24 PF00717.18 CCD26480.1 - 8.8e-08 31.6 0.0 1.6e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CCD26480.1 - 0.01 15.3 0.0 0.12 11.8 0.0 2.3 1 1 1 2 2 2 0 Signal peptidase, peptidase S26 ADH_zinc_N_2 PF13602.1 CCD26481.1 - 7.4e-12 46.2 0.0 1.5e-11 45.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCD26481.1 - 3.8e-06 26.4 0.0 1e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCD26481.1 - 0.0081 15.9 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Amelin PF05111.7 CCD26481.1 - 0.1 11.2 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) ADH_zinc_N_2 PF13602.1 CCD26482.1 - 6.6e-12 46.4 0.0 1.2e-11 45.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCD26482.1 - 5.9e-08 32.3 0.0 1.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.3 CCD26482.1 - 0.0021 17.2 0.0 0.0026 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) ADH_N PF08240.7 CCD26482.1 - 0.019 14.7 0.1 0.067 12.9 0.0 1.9 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 CCD26482.1 - 0.02 15.1 0.0 0.051 13.8 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DDT PF02791.12 CCD26482.1 - 0.074 12.8 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 0 DDT domain ADH_zinc_N_2 PF13602.1 CCD26483.1 - 1.2e-11 45.5 0.0 2.6e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCD26483.1 - 2.3e-08 33.6 0.0 7e-08 32.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCD26483.1 - 0.0089 15.7 0.0 0.027 14.2 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF2855 PF11017.3 CCD26483.1 - 0.013 14.6 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Nup35_RRM PF05172.8 CCD26484.1 - 1e-35 121.4 0.2 4.2e-35 119.5 0.0 2.1 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CCD26484.1 - 0.00017 21.2 0.1 0.00094 18.9 0.1 2.1 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif GST_C_2 PF13410.1 CCD26485.1 - 0.21 11.4 0.0 0.5 10.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PNK3P PF08645.6 CCD26486.1 - 4.6e-44 149.6 0.4 6.2e-44 149.2 0.3 1.2 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase Ribosomal_S8 PF00410.14 CCD26488.1 - 1.8e-23 82.8 0.0 2.1e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 ATG16 PF08614.6 CCD26489.1 - 3.3e-22 79.2 21.2 9.1e-20 71.3 13.4 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Fez1 PF06818.10 CCD26489.1 - 0.0035 17.3 7.0 0.0042 17.1 4.8 1.2 1 0 0 1 1 1 1 Fez1 GAS PF13851.1 CCD26489.1 - 0.026 13.7 18.8 0.083 12.0 11.5 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Ssu72 PF04722.8 CCD26489.1 - 0.047 12.9 4.4 0.053 12.8 3.0 1.1 1 0 0 1 1 1 0 Ssu72-like protein DUF3926 PF13080.1 CCD26489.1 - 0.047 13.2 0.1 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3926) Macoilin PF09726.4 CCD26489.1 - 0.056 11.7 7.1 0.06 11.6 4.9 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4201 PF13870.1 CCD26489.1 - 0.057 12.8 11.6 0.097 12.0 8.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.3 CCD26489.1 - 0.2 11.4 12.4 0.28 10.8 7.8 1.8 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Atg14 PF10186.4 CCD26489.1 - 0.26 10.1 9.7 0.34 9.8 6.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_2 PF01920.15 CCD26489.1 - 0.33 10.7 12.3 0.57 9.9 2.4 2.3 1 1 1 2 2 2 0 Prefoldin subunit FHIPEP PF00771.15 CCD26489.1 - 0.4 8.9 3.6 0.43 8.8 2.5 1.0 1 0 0 1 1 1 0 FHIPEP family APG6 PF04111.7 CCD26489.1 - 0.92 8.4 11.9 0.99 8.3 8.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 CCD26489.1 - 1.2 6.8 8.2 1.3 6.7 5.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF641 PF04859.7 CCD26489.1 - 1.3 8.7 8.9 3.3 7.4 5.7 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) SlyX PF04102.7 CCD26489.1 - 2.9 8.3 8.7 2.8 8.3 4.1 2.4 1 1 2 3 3 3 0 SlyX TMF_DNA_bd PF12329.3 CCD26489.1 - 3.1 7.6 17.4 0.23 11.3 4.4 2.5 2 1 1 3 3 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CCD26489.1 - 4.2 6.9 11.6 6.6 6.2 8.0 1.5 1 1 0 1 1 1 0 IncA protein Ly49 PF08391.5 CCD26489.1 - 4.8 7.3 9.3 2.8 8.0 5.0 1.7 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region Cep57_CLD_2 PF14197.1 CCD26489.1 - 7.9 6.5 15.9 2.1e+02 1.9 9.2 3.5 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 DnaJ PF00226.26 CCD26491.1 - 2.1e-26 91.4 0.5 3.6e-26 90.6 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain AbbA_antirepres PF14156.1 CCD26491.1 - 0.088 12.4 0.4 0.16 11.6 0.3 1.4 1 0 0 1 1 1 0 Antirepressor AbbA DUF633 PF04816.7 CCD26491.1 - 0.14 11.5 0.1 0.2 10.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) E1-E2_ATPase PF00122.15 CCD26492.1 - 5.9e-22 77.8 0.0 1.7e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCD26492.1 - 3e-16 60.4 0.0 6.1e-15 56.2 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCD26492.1 - 2.1e-14 54.1 1.7 5.6e-13 49.4 1.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCD26492.1 - 3.9e-12 45.9 0.0 2.8e-11 43.2 0.0 2.5 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Vezatin PF12632.2 CCD26493.1 - 1.3e-24 86.6 17.6 2.9e-24 85.5 12.2 1.6 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes BLYB PF05289.6 CCD26493.1 - 1.8 8.4 8.9 5.6 6.8 0.3 3.4 3 0 0 3 3 3 0 Borrelia hemolysin accessory protein LNS2 PF08235.8 CCD26494.1 - 1.4e-68 229.4 0.0 4.3e-68 227.8 0.0 1.9 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CCD26494.1 - 5.9e-43 145.0 0.0 1.6e-42 143.6 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region AF1Q PF15017.1 CCD26494.1 - 0.0042 16.9 1.9 0.0042 16.9 1.3 3.6 4 0 0 4 4 4 1 Drug resistance and apoptosis regulator Mito_carr PF00153.22 CCD26495.1 - 1.4e-54 181.7 3.3 1.6e-22 79.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DNA_mis_repair PF01119.14 CCD26496.1 - 1.9e-29 101.5 0.2 3.7e-29 100.5 0.1 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CCD26496.1 - 2.2e-15 56.5 0.1 8.2e-15 54.6 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCD26496.1 - 3.9e-10 39.4 0.0 9.6e-10 38.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zn_clus PF00172.13 CCD26497.1 - 7.1e-07 29.0 7.7 1.2e-06 28.2 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 CCD26498.1 - 2.7e-160 533.6 0.0 3.2e-160 533.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCD26498.1 - 0.048 12.3 0.1 0.41 9.2 0.0 2.0 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) SPRY PF00622.23 CCD26500.1 - 2.4e-12 47.0 0.0 4.9e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Inositol_P PF00459.20 CCD26500.1 - 0.04 13.2 0.1 0.1 11.8 0.1 1.6 1 0 0 1 1 1 0 Inositol monophosphatase family Herpes_LMP2 PF07415.6 CCD26500.1 - 0.35 9.3 9.9 0.79 8.2 6.8 1.5 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein HECT PF00632.20 CCD26501.1 - 3.4e-85 286.0 0.2 5.5e-85 285.3 0.2 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF4122 PF13498.1 CCD26501.1 - 0.12 11.6 1.9 0.19 11.0 0.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4122) Glyco_transf_22 PF03901.12 CCD26502.1 - 4e-100 335.7 42.2 4.7e-100 335.5 29.3 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family RF-1 PF00472.15 CCD26503.1 - 6.6e-39 132.2 3.4 1.4e-38 131.1 2.4 1.5 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CCD26503.1 - 2.1e-33 114.4 0.2 8.3e-33 112.5 0.0 2.1 2 0 0 2 2 2 1 PCRF domain MIR PF02815.14 CCD26503.1 - 0.01 15.3 3.8 0.078 12.5 0.6 2.3 2 0 0 2 2 2 0 MIR domain Cnd1_N PF12922.2 CCD26503.1 - 0.024 14.2 0.2 0.053 13.1 0.1 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term PEX11 PF05648.9 CCD26503.1 - 0.11 11.7 0.1 0.11 11.7 0.1 1.8 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) PP2C PF00481.16 CCD26504.1 - 1.1e-52 178.9 0.1 2e-52 178.1 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 CCD26504.1 - 3e-40 135.2 99.6 7.3e-07 28.6 6.0 13.2 8 2 6 15 15 15 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCD26504.1 - 7.1e-39 131.3 82.1 1.5e-09 37.4 5.8 9.4 6 2 1 8 8 8 7 Leucine rich repeat Guanylate_cyc PF00211.15 CCD26504.1 - 3.8e-23 81.7 0.0 7.2e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 CCD26504.1 - 3.6e-14 50.6 76.0 1.4 9.2 1.4 19.2 15 4 3 18 18 18 9 Leucine Rich Repeat RA PF00788.18 CCD26504.1 - 4.2e-08 33.5 0.0 9.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 CCD26504.1 - 1.6 9.3 65.2 11 6.6 0.1 18.0 18 1 1 19 19 19 0 Leucine rich repeat DUF676 PF05057.9 CCD26505.1 - 2.9e-59 199.9 0.0 5e-59 199.2 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CCD26505.1 - 0.00012 21.7 0.0 0.0004 20.0 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CCD26505.1 - 0.013 15.1 0.0 0.049 13.1 0.0 2.0 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_5 PF12695.2 CCD26505.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family RINT1_TIP1 PF04437.8 CCD26506.1 - 4.2e-101 338.9 28.9 4.2e-101 338.9 20.1 2.0 2 0 0 2 2 2 1 RINT-1 / TIP-1 family Polyoma_coat2 PF00761.15 CCD26506.1 - 1.6 8.1 4.2 13 5.1 0.2 2.6 2 1 1 3 3 3 0 Polyomavirus coat protein EMP24_GP25L PF01105.19 CCD26507.1 - 4.9e-12 45.9 0.0 6.7e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RNase_PH PF01138.16 CCD26508.1 - 1e-13 51.7 0.3 1.5e-13 51.1 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 MAP PF03642.8 CCD26508.1 - 0.033 14.4 0.4 0.087 13.0 0.2 1.8 1 1 0 1 1 1 0 MAP domain RNase_PH_C PF03725.10 CCD26508.1 - 0.049 13.5 0.1 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 3' exoribonuclease family, domain 2 Ribosomal_L6 PF00347.18 CCD26509.1 - 2.7e-28 98.2 12.8 2.1e-14 53.7 3.6 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 LRR_6 PF13516.1 CCD26509.1 - 0.18 11.9 0.3 5.2 7.4 0.0 2.9 3 0 0 3 3 3 0 Leucine Rich repeat Chorismate_synt PF01264.16 CCD26510.1 - 5.3e-135 449.3 0.1 6.1e-135 449.1 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Flavodoxin_2 PF02525.12 CCD26511.1 - 1.1e-54 184.9 0.0 1.5e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCD26511.1 - 3.7e-14 52.4 0.0 1.2e-13 50.7 0.0 1.8 2 1 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CCD26511.1 - 6.9e-05 22.2 0.2 0.00017 20.9 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin SNF2_N PF00176.18 CCD26512.1 - 1e-70 237.9 1.7 1e-70 237.9 1.2 3.2 4 0 0 4 4 4 1 SNF2 family N-terminal domain DBINO PF13892.1 CCD26512.1 - 4e-48 163.0 23.6 4e-48 163.0 16.4 4.6 4 0 0 4 4 4 1 DNA-binding domain Helicase_C PF00271.26 CCD26512.1 - 1.2e-13 50.7 0.0 5.1e-13 48.6 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Med5 PF08689.5 CCD26513.1 - 2.3e-249 830.0 54.2 2.7e-249 829.7 37.6 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 Pex14_N PF04695.8 CCD26514.1 - 8e-36 123.0 0.0 8e-36 123.0 0.0 2.5 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Alpha-2-MRAP_C PF06401.6 CCD26514.1 - 0.00071 19.4 5.8 0.0012 18.7 4.0 1.3 1 0 0 1 1 1 1 Alpha-2-macroglobulin RAP, C-terminal domain DUF1664 PF07889.7 CCD26514.1 - 0.0049 16.6 3.3 0.0082 15.9 1.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF892 PF05974.7 CCD26514.1 - 0.058 13.2 2.8 0.085 12.6 1.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF892) Prefoldin_2 PF01920.15 CCD26514.1 - 0.064 13.0 16.8 0.085 12.6 4.3 3.5 1 1 2 3 3 3 0 Prefoldin subunit DUF4449 PF14613.1 CCD26514.1 - 0.075 12.9 3.0 0.17 11.8 2.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4449) Baculo_PEP_C PF04513.7 CCD26514.1 - 0.088 12.6 7.2 0.25 11.1 4.8 1.8 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Syntaxin PF00804.20 CCD26514.1 - 0.11 12.6 14.0 4.8 7.4 5.8 3.4 1 1 1 2 2 2 0 Syntaxin CCDC-167 PF15188.1 CCD26514.1 - 0.24 11.3 9.9 1.6 8.7 0.4 2.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Spc7 PF08317.6 CCD26514.1 - 0.3 9.6 15.7 0.86 8.1 10.9 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.4 CCD26514.1 - 0.5 9.2 7.6 1.3 7.8 5.2 1.5 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 ALMT PF11744.3 CCD26514.1 - 0.51 8.9 5.0 2.6 6.6 3.2 1.9 1 1 0 1 1 1 0 Aluminium activated malate transporter APG6 PF04111.7 CCD26514.1 - 0.67 8.9 10.9 1.4 7.8 7.6 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1043 PF06295.7 CCD26514.1 - 0.82 9.3 9.9 2.7 7.6 2.3 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF1043) Occludin_ELL PF07303.8 CCD26514.1 - 1.1 10.0 7.1 19 6.0 3.4 2.8 1 1 1 2 2 2 0 Occludin homology domain LURAP PF14854.1 CCD26514.1 - 1.2 8.8 4.7 0.38 10.4 0.2 2.3 2 1 1 3 3 3 0 Leucine rich adaptor protein IncA PF04156.9 CCD26514.1 - 2.2 7.8 10.8 4.9 6.7 7.5 1.5 1 1 0 1 1 1 0 IncA protein Enkurin PF13864.1 CCD26514.1 - 3.7 7.7 10.5 4.9 7.4 6.1 2.1 1 1 1 2 2 2 0 Calmodulin-binding Syntaxin-6_N PF09177.6 CCD26514.1 - 4.1 7.8 10.0 3.7 8.0 2.1 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Ax_dynein_light PF10211.4 CCD26514.1 - 4.7 7.0 14.2 6 6.6 4.3 2.5 1 1 1 2 2 2 0 Axonemal dynein light chain SlyX PF04102.7 CCD26514.1 - 4.7 7.6 7.6 0.71 10.2 1.0 2.6 2 1 1 3 3 3 0 SlyX ACPS PF01648.15 CCD26515.1 - 4.3e-09 36.1 0.0 7.2e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily TilS PF09179.6 CCD26515.1 - 0.077 13.0 0.3 0.14 12.2 0.2 1.3 1 0 0 1 1 1 0 TilS substrate binding domain Prenyltrans PF00432.16 CCD26516.1 - 4.2e-30 102.9 10.3 1.3e-07 31.0 0.1 6.1 7 1 0 7 7 7 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCD26516.1 - 1.8e-20 73.4 0.0 1.2e-08 35.2 0.0 3.6 1 1 3 4 4 4 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCD26516.1 - 0.00051 20.0 0.0 0.02 14.9 0.0 2.9 2 1 1 3 3 3 1 Prenyltransferase-like Acetyltransf_4 PF13420.1 CCD26516.1 - 0.07 13.0 0.3 0.46 10.4 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain NAD_binding_6 PF08030.7 CCD26517.1 - 1.2e-16 61.0 0.2 1.8e-16 60.4 0.2 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 CCD26517.1 - 3.3e-14 53.0 10.5 3.3e-14 53.0 7.3 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 CCD26517.1 - 0.00017 21.4 0.1 0.00042 20.1 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain MecA PF05389.7 CCD26517.1 - 0.0073 15.8 2.5 0.012 15.1 1.7 1.3 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) Peptidase_M50 PF02163.17 CCD26517.1 - 0.013 14.4 3.6 0.16 10.9 0.0 3.0 3 0 0 3 3 3 0 Peptidase family M50 Glyco_hydro_38 PF01074.17 CCD26518.1 - 1e-82 277.4 0.4 1.7e-82 276.7 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CCD26518.1 - 5e-66 223.3 1.6 7e-66 222.9 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CCD26518.1 - 4.3e-24 84.5 0.0 1.5e-23 82.7 0.0 2.0 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Pkinase PF00069.20 CCD26519.1 - 1.2e-62 211.3 0.0 2e-62 210.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26519.1 - 5.2e-27 94.5 0.0 1.2e-26 93.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD26519.1 - 8.4e-06 24.9 0.1 0.04 12.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CCD26519.1 - 0.0048 15.9 0.0 0.0089 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD26519.1 - 0.015 15.0 0.0 0.23 11.1 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family UPF0029 PF01205.14 CCD26520.1 - 1.1e-33 115.1 0.3 2e-33 114.3 0.2 1.4 1 1 0 1 1 1 1 Uncharacterized protein family UPF0029 VitD-bind_III PF09164.5 CCD26520.1 - 0.04 13.5 0.2 0.073 12.6 0.1 1.5 1 0 0 1 1 1 0 Vitamin D binding protein, domain III TraH_2 PF06871.6 CCD26520.1 - 0.072 12.5 0.4 3.7 6.9 0.0 2.2 1 1 0 2 2 2 0 TraH_2 DNase_NucA_NucB PF14040.1 CCD26520.1 - 0.073 13.2 0.6 0.13 12.4 0.4 1.3 1 0 0 1 1 1 0 Deoxyribonuclease NucA/NucB OCD_Mu_crystall PF02423.10 CCD26522.1 - 4.3e-09 35.5 0.1 3.2e-06 26.1 0.0 2.4 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Nsp3_PL2pro PF12124.3 CCD26522.1 - 0.07 12.6 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 0 Coronavirus polyprotein cleavage domain SH3BGR PF04908.10 CCD26523.1 - 0.019 14.8 0.0 0.019 14.8 0.0 3.8 4 0 0 4 4 4 0 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 CCD26523.1 - 0.049 13.6 0.0 0.31 11.0 0.0 2.5 1 0 0 1 1 1 0 Glutaredoxin Glycogen_syn PF05693.8 CCD26524.1 - 0 1118.3 0.0 0 1118.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CCD26524.1 - 6e-09 35.5 0.0 2.3e-05 23.8 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCD26524.1 - 1.1e-05 25.6 0.1 2.2e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Pkinase PF00069.20 CCD26525.1 - 9.8e-72 241.2 0.0 1.6e-71 240.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26525.1 - 4.6e-41 140.6 0.0 6.9e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.11 CCD26525.1 - 0.015 15.2 0.0 0.053 13.4 0.0 1.8 2 0 0 2 2 2 0 ABC1 family YrbL-PhoP_reg PF10707.4 CCD26525.1 - 0.035 13.4 0.3 0.035 13.4 0.2 1.9 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 CCD26525.1 - 0.2 10.6 0.0 0.2 10.6 0.0 1.7 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ins_allergen_rp PF06757.8 CCD26526.1 - 0.0078 15.7 0.4 0.025 14.0 0.3 1.8 1 0 0 1 1 1 1 Insect allergen related repeat, nitrile-specifier detoxification WHIM1 PF15612.1 CCD26526.1 - 0.019 14.9 0.0 0.061 13.2 0.0 2.0 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 DUF1690 PF07956.6 CCD26527.1 - 2.4e-30 105.3 20.5 2.2e-28 99.0 13.7 2.2 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF789 PF05623.7 CCD26527.1 - 1.9 7.8 4.9 2.5 7.5 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) DUF607 PF04678.8 CCD26527.1 - 8.2 6.3 6.8 1e+02 2.7 4.7 2.1 1 1 0 1 1 1 0 Protein of unknown function, DUF607 UCH PF00443.24 CCD26528.1 - 1.6e-51 174.9 6.6 2e-51 174.6 4.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCD26528.1 - 3e-16 59.7 12.0 8.1e-16 58.3 8.3 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CCD26528.1 - 1.5e-06 27.4 0.1 4.5e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family RNB PF00773.14 CCD26529.1 - 3.6e-93 312.4 0.7 2.7e-92 309.5 0.0 2.1 2 0 0 2 2 2 1 RNB domain PIN_4 PF13638.1 CCD26529.1 - 4e-14 52.8 1.2 9.4e-14 51.6 0.8 1.6 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 CCD26529.1 - 0.016 14.6 0.0 0.058 12.9 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain ABC_tran PF00005.22 CCD26530.1 - 4.9e-47 159.6 0.2 1.6e-22 80.2 0.0 3.0 2 0 0 2 2 2 2 ABC transporter ABC_tran_2 PF12848.2 CCD26530.1 - 4.1e-19 68.1 10.8 4.1e-19 68.1 7.5 2.8 4 0 0 4 4 1 1 ABC transporter AAA_21 PF13304.1 CCD26530.1 - 1.3e-15 58.1 12.1 5.1e-05 23.3 0.0 5.2 3 2 2 5 5 5 3 AAA domain SMC_N PF02463.14 CCD26530.1 - 1e-10 41.2 0.0 0.00023 20.4 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCD26530.1 - 2.2e-09 38.1 0.5 0.00029 21.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.1 CCD26530.1 - 1.9e-07 31.2 0.7 0.013 15.4 0.1 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_28 PF13521.1 CCD26530.1 - 2e-07 31.0 0.1 0.028 14.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CCD26530.1 - 7.8e-07 28.8 0.0 0.006 16.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.1 CCD26530.1 - 1.1e-06 28.0 1.5 0.059 12.9 0.0 3.1 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 CCD26530.1 - 1.4e-06 27.5 0.0 0.035 13.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 CCD26530.1 - 2e-06 28.3 0.1 0.088 13.3 0.0 3.0 2 1 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 CCD26530.1 - 4.3e-06 26.8 0.9 0.3 11.2 0.0 3.8 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.1 CCD26530.1 - 1.4e-05 25.0 0.2 0.15 11.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 CCD26530.1 - 1.7e-05 25.0 0.1 0.094 12.9 0.0 3.7 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 CCD26530.1 - 2e-05 24.2 0.0 0.0068 15.9 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_18 PF13238.1 CCD26530.1 - 2.8e-05 24.4 10.9 0.15 12.3 0.9 4.5 5 1 0 5 5 3 2 AAA domain AAA_33 PF13671.1 CCD26530.1 - 5.5e-05 23.0 0.0 0.18 11.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain PduV-EutP PF10662.4 CCD26530.1 - 6.7e-05 22.4 0.1 0.11 11.9 0.0 2.7 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CCD26530.1 - 7.7e-05 22.6 0.0 0.11 12.4 0.0 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 CCD26530.1 - 9.4e-05 22.1 0.0 0.52 10.0 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CCD26530.1 - 0.00016 21.2 0.1 1.2 8.5 0.0 3.6 4 0 0 4 4 4 2 AAA-like domain AAA_23 PF13476.1 CCD26530.1 - 0.00021 21.6 26.7 0.36 11.1 0.0 5.3 5 0 0 5 5 5 2 AAA domain RNA_helicase PF00910.17 CCD26530.1 - 0.00043 20.4 0.6 0.52 10.5 0.0 3.2 3 0 0 3 3 2 1 RNA helicase NB-ARC PF00931.17 CCD26530.1 - 0.00074 18.4 0.0 0.88 8.3 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain NTPase_1 PF03266.10 CCD26530.1 - 0.00076 19.2 0.0 0.32 10.6 0.0 2.6 2 0 0 2 2 2 1 NTPase Dynamin_N PF00350.18 CCD26530.1 - 0.00092 19.0 2.8 0.17 11.7 0.0 3.7 4 0 0 4 4 3 1 Dynamin family SbcCD_C PF13558.1 CCD26530.1 - 0.0012 18.6 0.2 1.7 8.5 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 CCD26530.1 - 0.0013 17.5 0.0 0.2 10.3 0.0 2.6 2 0 0 2 2 2 1 ArgK protein AAA_25 PF13481.1 CCD26530.1 - 0.0018 17.6 0.0 1.8 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain Blo-t-5 PF11642.3 CCD26530.1 - 0.0022 17.7 0.8 0.0022 17.7 0.6 2.4 2 0 0 2 2 1 1 Mite allergen Blo t 5 AAA_15 PF13175.1 CCD26530.1 - 0.0038 16.3 23.2 0.059 12.4 1.1 5.8 3 2 1 5 5 5 2 AAA ATPase domain AAA_5 PF07728.9 CCD26530.1 - 0.0039 16.9 1.6 3.4 7.3 0.0 3.2 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CCD26530.1 - 0.0048 16.0 0.0 0.77 8.8 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.8 CCD26530.1 - 0.005 15.7 0.1 2.8 6.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 CCD26530.1 - 0.0068 15.9 0.1 0.86 9.0 0.0 2.9 3 0 0 3 3 3 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 CCD26530.1 - 0.0079 15.5 0.1 0.15 11.3 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein Arch_ATPase PF01637.13 CCD26530.1 - 0.0093 15.6 10.1 0.048 13.3 0.0 3.4 4 0 0 4 4 4 2 Archaeal ATPase cobW PF02492.14 CCD26530.1 - 0.015 14.7 0.1 1.8 8.0 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 CCD26530.1 - 0.018 13.9 0.0 0.21 10.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein FeoB_N PF02421.13 CCD26530.1 - 0.019 14.2 0.1 5.7 6.1 0.0 2.8 3 0 0 3 3 2 0 Ferrous iron transport protein B SRP54 PF00448.17 CCD26530.1 - 0.026 13.9 0.1 2.3 7.6 0.0 2.9 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain UPF0079 PF02367.12 CCD26530.1 - 0.073 12.6 0.1 0.97 9.0 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Viral_helicase1 PF01443.13 CCD26530.1 - 0.092 12.2 0.0 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Ras PF00071.17 CCD26530.1 - 0.12 11.7 2.0 7 6.0 0.0 3.1 3 0 0 3 3 3 0 Ras family DUF2813 PF11398.3 CCD26530.1 - 0.13 11.3 5.3 0.46 9.4 0.0 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF2813) DUF87 PF01935.12 CCD26530.1 - 0.65 9.7 0.0 0.65 9.7 0.0 5.2 4 1 1 5 5 5 0 Domain of unknown function DUF87 Rep_Org_C PF06926.6 CCD26531.1 - 0.091 12.8 0.3 0.091 12.8 0.2 2.5 3 0 0 3 3 3 0 Putative replisome organiser protein C-terminus YABBY PF04690.8 CCD26531.1 - 4.5 7.4 5.9 7.6 6.7 0.5 2.5 2 1 0 2 2 2 0 YABBY protein Peptidase_M28 PF04389.12 CCD26532.1 - 1e-32 113.3 0.0 2e-32 112.4 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M28 PriCT_2 PF08707.6 CCD26532.1 - 0.12 12.2 0.6 0.26 11.2 0.1 1.7 2 0 0 2 2 2 0 Primase C terminal 2 (PriCT-2) PIP5K PF01504.13 CCD26533.1 - 6.4e-66 222.0 0.3 4.4e-65 219.2 0.2 2.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CCD26533.1 - 1e-26 93.6 0.1 2.2e-26 92.5 0.1 1.5 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CCD26533.1 - 1.9e-17 62.8 7.8 1.9e-17 62.8 5.4 1.8 2 0 0 2 2 2 1 FYVE zinc finger WD40 PF00400.27 CCD26534.1 - 8e-10 38.2 0.1 0.00025 20.8 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat Arrestin_C PF02752.17 CCD26535.1 - 6.4e-22 78.1 1.7 2.4e-20 73.0 0.4 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCD26535.1 - 1.5e-08 34.5 0.1 1.7e-07 31.1 0.1 2.3 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CCD26535.1 - 0.0011 18.4 0.0 0.011 15.2 0.0 2.4 2 0 0 2 2 2 1 Arrestin_N terminal like Asparaginase PF00710.15 CCD26536.1 - 1.6e-15 56.8 6.1 7.7e-15 54.5 4.2 2.1 1 1 0 1 1 1 1 Asparaginase Far-17a_AIG1 PF04750.9 CCD26537.1 - 4.1e-18 65.2 6.1 5.2e-18 64.9 4.2 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Ribosomal_L44 PF00935.14 CCD26538.1 - 2.6e-34 117.0 11.0 3.9e-34 116.4 7.6 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Chs3p PF12271.3 CCD26539.1 - 3.1e-98 328.3 21.9 6.8e-98 327.2 15.2 1.5 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit Macoilin PF09726.4 CCD26540.1 - 2.6 6.2 16.8 2.8 6.0 11.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DNA_RNApol_7kD PF03604.8 CCD26541.1 - 1.9e-16 59.2 1.8 2.5e-16 58.8 1.3 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 CCD26541.1 - 0.0032 17.2 0.5 0.0044 16.8 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 CCD26541.1 - 0.0033 17.0 0.2 0.0035 16.9 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family Prok-RING_1 PF14446.1 CCD26541.1 - 0.007 16.0 0.7 0.0092 15.6 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 TFIIS_C PF01096.13 CCD26541.1 - 0.0074 15.9 1.0 2.9 7.6 0.1 2.3 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) NCD3G PF07562.9 CCD26541.1 - 0.027 14.1 0.3 0.033 13.8 0.2 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR FYDLN_acid PF09538.5 CCD26541.1 - 0.028 14.9 0.3 0.034 14.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) C1_1 PF00130.17 CCD26541.1 - 0.037 13.7 0.4 0.053 13.2 0.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF2318 PF10080.4 CCD26541.1 - 0.057 13.1 0.1 0.064 13.0 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) A2L_zn_ribbon PF08792.5 CCD26541.1 - 0.061 12.8 0.9 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF951 PF06107.6 CCD26541.1 - 0.062 12.8 1.5 1.5 8.3 0.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) DUF4428 PF14471.1 CCD26541.1 - 0.068 12.9 1.6 1.5 8.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) FYVE_2 PF02318.11 CCD26541.1 - 0.076 12.9 0.4 0.084 12.7 0.3 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger DUF2197 PF09963.4 CCD26541.1 - 0.08 12.9 2.3 7 6.6 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Gin PF10764.4 CCD26541.1 - 0.12 12.0 0.2 1.4 8.7 0.0 2.2 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin Herpes_UL33 PF03581.8 CCD26541.1 - 0.13 12.1 0.2 0.16 11.8 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL33-like protein Zn_ribbon_recom PF13408.1 CCD26541.1 - 0.21 11.8 3.2 3.4 8.0 0.5 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L40e PF01020.12 CCD26541.1 - 0.3 10.6 2.7 0.4 10.3 1.9 1.2 1 0 0 1 1 1 0 Ribosomal L40e family Zn-ribbon_8 PF09723.5 CCD26541.1 - 0.36 10.8 3.4 1.2 9.2 2.3 1.8 1 1 0 1 1 1 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CCD26541.1 - 0.43 10.4 3.0 2 8.2 2.4 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 CCD26541.1 - 0.6 9.4 2.6 8.2 5.8 2.1 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 CCD26541.1 - 1.1 8.9 3.3 6.6 6.4 2.3 2.2 1 1 0 1 1 1 0 zinc-ribbon domain Ribosomal_L44 PF00935.14 CCD26541.1 - 1.9 8.5 4.9 11 6.1 0.5 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 NOT2_3_5 PF04153.13 CCD26543.1 - 1.9 8.3 5.7 3.5 7.5 2.0 2.7 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family SHR3_chaperone PF08229.6 CCD26544.1 - 7.5e-76 253.4 0.7 9.2e-76 253.1 0.5 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4446 PF14584.1 CCD26544.1 - 0.064 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Ras PF00071.17 CCD26545.1 - 5.4e-43 146.1 0.1 8e-43 145.6 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD26545.1 - 9.3e-13 48.7 0.0 9.1e-12 45.5 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CCD26545.1 - 1.3e-05 24.7 0.2 4.5e-05 22.9 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CCD26545.1 - 7.1e-05 22.1 0.5 0.00019 20.7 0.3 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family RRM_1 PF00076.17 CCD26546.1 - 3.3e-06 26.6 0.0 7.5e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD26546.1 - 4.5e-05 23.3 0.0 8.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PUL PF08324.6 CCD26546.1 - 0.09 11.5 1.7 0.18 10.6 1.2 1.4 1 0 0 1 1 1 0 PUL domain RHH_1 PF01402.16 CCD26546.1 - 1.2 9.1 5.5 0.19 11.6 0.6 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Pkinase PF00069.20 CCD26547.1 - 5.1e-56 189.7 0.1 5.1e-56 189.7 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26547.1 - 1.8e-17 63.2 0.0 4.2e-17 62.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCD26547.1 - 0.17 11.5 0.1 0.3 10.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ELFV_dehydrog PF00208.16 CCD26548.1 - 1.3e-56 191.9 0.2 5.5e-55 186.5 0.1 2.4 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CCD26548.1 - 2e-18 65.3 0.4 1.2e-11 42.9 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase Cadherin_2 PF08266.7 CCD26548.1 - 0.039 13.5 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 0 Cadherin-like ELFV_dehydrog_N PF02812.13 CCD26548.1 - 0.063 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain JAB PF01398.16 CCD26549.1 - 4.4e-27 94.0 0.1 1.2e-26 92.7 0.1 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CCD26549.1 - 3.9e-07 29.5 0.0 7.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CCD26549.1 - 0.033 13.6 0.2 0.32 10.4 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0172) Tim17 PF02466.14 CCD26550.1 - 6e-47 158.8 5.8 8e-47 158.4 4.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.13 CCD26550.1 - 0.033 13.4 0.1 0.12 11.6 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Arm PF00514.18 CCD26551.1 - 1.2e-22 78.8 10.2 2.2e-05 24.0 0.1 7.6 8 0 0 8 8 8 5 Armadillo/beta-catenin-like repeat IBB PF01749.15 CCD26551.1 - 3.1e-11 43.3 1.4 1e-10 41.6 0.9 1.9 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 CCD26551.1 - 0.0062 16.9 0.0 13 6.4 0.0 4.0 4 0 0 4 4 4 2 HEAT-like repeat Gly-zipper_Omp PF13488.1 CCD26552.1 - 0.26 10.9 12.3 1.1 9.0 8.5 2.1 1 1 0 1 1 1 0 Glycine zipper Rick_17kDa_Anti PF05433.10 CCD26552.1 - 0.6 9.8 14.3 0.75 9.5 8.3 2.1 1 1 1 2 2 2 0 Glycine zipper 2TM domain MARVEL PF01284.18 CCD26553.1 - 7e-27 94.0 11.5 1.1e-26 93.3 8.0 1.3 1 0 0 1 1 1 1 Membrane-associating domain TRP PF06011.7 CCD26553.1 - 0.0091 14.6 3.1 0.67 8.4 0.7 2.3 2 0 0 2 2 2 2 Transient receptor potential (TRP) ion channel DUF4064 PF13273.1 CCD26553.1 - 2.3 8.3 6.7 16 5.6 3.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Amastin PF07344.6 CCD26553.1 - 4.1 7.0 11.3 34 4.0 7.8 2.1 1 1 0 1 1 1 0 Amastin surface glycoprotein Tic20 PF09685.5 CCD26553.1 - 8.2 6.4 10.5 6.9 6.7 4.3 2.1 2 0 0 2 2 2 0 Tic20-like protein Tyr_Deacylase PF02580.11 CCD26554.1 - 3.4e-51 173.0 0.3 3.8e-51 172.8 0.2 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Glyco_hydro_8 PF01270.12 CCD26554.1 - 0.061 12.0 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 8 SUR7 PF06687.7 CCD26556.1 - 1.6e-41 142.1 4.9 2.2e-41 141.7 3.4 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CCD26556.1 - 4e-06 26.6 1.9 4e-06 26.6 1.3 1.8 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Fig1 PF12351.3 CCD26556.1 - 0.0059 16.5 5.2 0.01 15.7 3.6 1.3 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 Hum_adeno_E3A PF05393.6 CCD26556.1 - 0.018 14.6 0.6 0.88 9.2 0.0 2.4 2 0 0 2 2 2 0 Human adenovirus early E3A glycoprotein InvH PF04741.7 CCD26556.1 - 0.053 13.3 0.6 0.11 12.3 0.4 1.5 1 0 0 1 1 1 0 InvH outer membrane lipoprotein TatC PF00902.13 CCD26556.1 - 1.2 8.4 12.3 0.47 9.8 6.1 1.9 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) DUF4131 PF13567.1 CCD26556.1 - 1.6 8.0 6.0 1.5 8.2 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3278 PF11683.3 CCD26556.1 - 3 7.8 7.1 2.9 7.9 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) DUF2628 PF10947.3 CCD26556.1 - 3.4 7.4 10.7 0.37 10.6 2.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2628) DUF204 PF02659.10 CCD26556.1 - 6.7 6.9 9.3 0.44 10.7 2.6 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF FUSC-like PF12805.2 CCD26557.1 - 0.073 11.9 0.3 78 2.0 0.0 3.9 4 0 0 4 4 4 0 FUSC-like inner membrane protein yccS RRM_1 PF00076.17 CCD26558.1 - 5.5e-14 51.5 0.0 5.3e-13 48.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD26558.1 - 1.7e-06 27.9 0.0 1.1e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Septin PF00735.13 CCD26559.1 - 1.4e-71 240.8 8.1 2.9e-70 236.4 5.6 2.5 1 1 0 1 1 1 1 Septin Sigma_1s PF02454.11 CCD26559.1 - 0.00074 19.2 0.0 0.0023 17.6 0.0 1.8 1 0 0 1 1 1 1 Sigma 1s protein AAA_33 PF13671.1 CCD26559.1 - 0.0011 18.8 0.0 0.0064 16.3 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 CCD26559.1 - 0.0014 18.8 1.0 0.0042 17.2 0.0 2.4 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 CCD26559.1 - 0.0034 17.6 4.3 0.045 14.0 0.0 3.3 2 2 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CCD26559.1 - 0.0037 16.7 0.2 0.0098 15.3 0.0 1.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_10 PF12846.2 CCD26559.1 - 0.013 14.9 3.0 0.051 12.9 0.0 2.6 2 1 0 2 2 2 0 AAA-like domain DUF258 PF03193.11 CCD26559.1 - 0.015 14.4 0.0 0.035 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AIG1 PF04548.11 CCD26559.1 - 0.019 14.0 1.9 0.14 11.2 0.0 2.4 2 0 0 2 2 2 0 AIG1 family AAA_17 PF13207.1 CCD26559.1 - 0.036 14.8 4.3 0.059 14.1 0.7 3.2 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 CCD26559.1 - 0.053 13.3 0.0 0.053 13.3 0.0 3.1 3 1 0 3 3 3 0 Dynamin family AAA PF00004.24 CCD26559.1 - 0.061 13.5 0.1 0.18 12.0 0.0 1.9 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CCD26559.1 - 0.11 11.6 0.2 0.47 9.5 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Synaptobrevin PF00957.16 CCD26559.1 - 1.9 8.1 5.5 0.46 10.1 0.7 2.3 3 0 0 3 3 3 0 Synaptobrevin Macoilin PF09726.4 CCD26560.1 - 0.2 9.8 24.8 0.0053 15.1 8.0 2.2 2 0 0 2 2 2 0 Transmembrane protein ArfGap PF01412.13 CCD26561.1 - 5e-34 116.5 0.0 5e-34 116.5 0.0 2.3 2 1 0 2 2 2 1 Putative GTPase activating protein for Arf DUF3582 PF12122.3 CCD26561.1 - 0.0075 16.2 1.5 0.034 14.1 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3582) Cytochrome_CBB3 PF13442.1 CCD26561.1 - 0.021 14.9 0.7 9 6.5 0.0 3.1 2 1 0 2 2 2 0 Cytochrome C oxidase, cbb3-type, subunit III Hom_end PF05204.9 CCD26562.1 - 5.1e-41 139.0 0.0 4.9e-36 123.0 0.0 2.6 2 0 0 2 2 2 2 Homing endonuclease Hom_end_hint PF05203.11 CCD26562.1 - 4.1e-34 118.1 0.0 5.4e-34 117.8 0.0 1.1 1 0 0 1 1 1 1 Hom_end-associated Hint LAGLIDADG_3 PF14528.1 CCD26562.1 - 2.9e-08 33.8 0.0 7.7e-06 26.0 0.0 2.7 2 0 0 2 2 2 1 LAGLIDADG-like domain NinE PF05322.6 CCD26562.1 - 0.036 13.7 0.9 0.1 12.3 0.2 2.1 2 0 0 2 2 2 0 NINE Protein DUF1794 PF08768.6 CCD26562.1 - 0.048 13.5 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1794) HSP70 PF00012.15 CCD26563.1 - 2.8e-235 781.8 7.3 3.1e-235 781.7 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCD26563.1 - 6e-16 57.9 0.5 2e-14 52.9 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CCD26563.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF2603 PF10788.4 CCD26563.1 - 0.042 13.6 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) FtsA PF14450.1 CCD26563.1 - 0.071 12.9 5.5 28 4.5 2.2 4.3 2 1 0 2 2 2 0 Cell division protein FtsA Y_phosphatase PF00102.22 CCD26564.1 - 1.5e-55 188.1 4.0 6.2e-55 186.0 2.8 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CCD26564.1 - 0.0003 20.3 0.1 0.0006 19.3 0.1 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCD26564.1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CCD26564.1 - 0.0025 17.8 0.2 0.014 15.4 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate DUF2422 PF10337.4 CCD26565.1 - 7.3e-08 31.6 4.4 7.3e-08 31.6 3.0 3.2 1 1 1 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CCD26565.1 - 6.9e-07 29.2 10.1 6.9e-07 29.2 7.0 2.9 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 CCD26565.1 - 5.9e-06 26.0 0.0 1.4e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC PF04632.7 CCD26565.1 - 0.0007 18.1 1.0 0.042 12.3 0.3 2.2 2 0 0 2 2 2 2 Fusaric acid resistance protein family ALMT PF11744.3 CCD26565.1 - 0.0011 17.7 5.2 0.31 9.6 0.0 3.1 3 0 0 3 3 3 2 Aluminium activated malate transporter LIM_bind PF01803.11 CCD26566.1 - 2.3e-43 148.0 4.3 6.1e-35 120.4 0.7 4.4 3 2 0 4 4 4 3 LIM-domain binding protein PAPA-1 PF04795.7 CCD26567.1 - 1.1e-08 35.6 12.3 1.1e-08 35.6 8.6 4.4 2 2 2 4 4 4 1 PAPA-1-like conserved region RabGAP-TBC PF00566.13 CCD26568.1 - 1.7e-32 112.6 16.4 1.9e-30 105.9 5.4 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain Flavodoxin_2 PF02525.12 CCD26569.1 - 2.9e-53 180.3 0.0 3.9e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCD26569.1 - 7.4e-14 51.5 0.0 2.5e-13 49.8 0.0 1.8 2 1 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CCD26569.1 - 1.9e-05 24.0 0.2 5e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin Hpt PF01627.18 CCD26570.1 - 8.3e-14 51.3 0.0 1.3e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Hydrolase_6 PF13344.1 CCD26571.1 - 8e-28 96.2 0.0 1.9e-27 95.0 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCD26571.1 - 5.7e-14 53.0 0.0 1e-13 52.2 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCD26571.1 - 1.6e-11 43.6 0.0 2.8e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 CCD26571.1 - 0.0015 18.8 0.0 0.06 13.5 0.1 2.6 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_phosphat_B PF03767.9 CCD26571.1 - 0.031 13.6 0.1 0.049 12.9 0.1 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Amidohydro_1 PF01979.15 CCD26573.1 - 1.1e-45 156.7 0.0 1.3e-45 156.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 CCD26573.1 - 4.7e-07 29.3 0.1 0.00018 20.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 CCD26573.1 - 0.00048 19.8 0.0 0.0014 18.3 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase A_deaminase PF00962.17 CCD26573.1 - 0.03 13.2 0.1 0.05 12.5 0.1 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 CCD26573.1 - 0.03 14.3 0.0 9.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase G6PD_C PF02781.11 CCD26574.1 - 9.5e-123 408.7 0.0 1.4e-122 408.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CCD26574.1 - 3.9e-63 212.9 0.0 2.9e-62 210.1 0.0 2.0 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, NAD binding domain RhoGAP PF00620.22 CCD26575.1 - 1.9e-36 124.9 1.6 2e-35 121.6 0.2 2.8 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 CCD26575.1 - 8.5e-30 102.6 56.6 3.8e-10 39.6 7.1 5.0 4 1 0 4 4 4 4 LIM domain Siva PF05458.7 CCD26575.1 - 0.1 12.1 5.5 0.33 10.4 3.8 1.8 1 0 0 1 1 1 0 Cd27 binding protein (Siva) FAD-oxidase_C PF02913.14 CCD26576.1 - 1.1e-48 165.7 0.0 1.7e-48 165.1 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCD26576.1 - 1.3e-35 121.9 0.0 2.2e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Helicase_C PF00271.26 CCD26579.1 - 2.1e-12 46.7 0.0 4.6e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD26579.1 - 5.9e-08 32.3 0.0 1.4e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF258 PF03193.11 CCD26580.1 - 0.032 13.4 0.0 0.044 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF3921 PF13060.1 CCD26580.1 - 1.5 8.7 4.0 16 5.4 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) Aa_trans PF01490.13 CCD26582.1 - 5.1e-75 252.4 37.6 5.8e-75 252.3 26.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAT1 PF09770.4 CCD26583.1 - 2.1e-235 783.7 67.7 1.2e-233 777.8 46.9 2.0 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 P34-Arc PF04045.9 CCD26584.1 - 2.3e-93 311.9 2.0 3e-93 311.5 1.4 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF1132 PF06575.7 CCD26584.1 - 0.00012 22.2 1.2 0.0003 20.9 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1132) PP2C PF00481.16 CCD26585.1 - 6.3e-31 107.6 0.0 1e-29 103.7 0.0 2.3 1 1 1 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 CCD26585.1 - 0.081 12.3 0.0 0.68 9.2 0.0 2.2 1 1 0 1 1 1 0 Protein phosphatase 2C Med12 PF09497.5 CCD26586.1 - 2.8e-25 88.0 0.3 9.3e-25 86.3 0.2 2.0 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 DUF2499 PF10693.4 CCD26586.1 - 0.012 15.6 1.4 0.03 14.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2499) Utp21 PF04192.7 CCD26587.1 - 0.045 12.8 0.6 0.048 12.7 0.4 1.1 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain Thioredoxin PF00085.15 CCD26588.1 - 1.5e-26 92.0 0.2 3.7e-26 90.8 0.1 1.5 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 CCD26588.1 - 4.3e-07 29.9 0.2 3.9e-05 23.6 0.0 2.3 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 CCD26588.1 - 8.1e-06 26.0 0.1 8.1e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CCD26588.1 - 1.2e-05 24.9 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.1 CCD26588.1 - 0.00015 21.3 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein AhpC-TSA PF00578.16 CCD26588.1 - 0.00024 20.7 0.1 0.00037 20.1 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCD26588.1 - 0.00045 19.7 0.1 0.063 12.8 0.1 2.2 1 1 1 2 2 2 2 Redoxin Phosducin PF02114.11 CCD26588.1 - 0.01 14.5 0.0 0.012 14.3 0.0 1.0 1 0 0 1 1 1 0 Phosducin KaiB PF07689.7 CCD26588.1 - 0.049 13.0 0.0 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 KaiB domain Thioredoxin_7 PF13899.1 CCD26588.1 - 0.068 13.2 0.2 0.17 11.9 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like DUF953 PF06110.6 CCD26588.1 - 0.098 12.1 0.1 0.17 11.3 0.1 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_3 PF13192.1 CCD26588.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.6 2 0 0 2 2 2 0 Thioredoxin domain Csm1 PF12539.3 CCD26589.1 - 2.3e-32 111.3 0.1 5e-32 110.2 0.1 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 TPR_MLP1_2 PF07926.7 CCD26589.1 - 0.00071 19.3 3.3 0.0014 18.3 2.3 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Spore_YpjB PF09577.5 CCD26589.1 - 0.0038 16.8 0.3 0.005 16.4 0.2 1.3 1 0 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) ADIP PF11559.3 CCD26589.1 - 0.004 17.0 5.1 0.0064 16.4 3.5 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding Transposase_22 PF02994.9 CCD26589.1 - 0.0067 14.9 0.6 0.0089 14.5 0.4 1.1 1 0 0 1 1 1 1 L1 transposable element Uso1_p115_C PF04871.8 CCD26589.1 - 0.008 16.1 4.7 0.012 15.5 3.2 1.2 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Tropomyosin PF00261.15 CCD26589.1 - 0.0088 15.1 4.2 0.013 14.5 2.9 1.2 1 0 0 1 1 1 1 Tropomyosin Spc7 PF08317.6 CCD26589.1 - 0.01 14.4 1.1 0.014 14.0 0.7 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein GAT PF03127.9 CCD26589.1 - 0.013 15.4 4.5 0.014 15.3 1.9 1.9 2 1 1 3 3 2 0 GAT domain SlyX PF04102.7 CCD26589.1 - 0.014 15.7 2.5 0.014 15.7 1.7 1.9 2 0 0 2 2 1 0 SlyX DUF4559 PF15112.1 CCD26589.1 - 0.014 14.5 2.3 0.022 13.9 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) HALZ PF02183.13 CCD26589.1 - 0.015 14.9 0.5 0.068 12.9 0.3 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF16 PF01519.11 CCD26589.1 - 0.018 15.2 3.6 0.029 14.5 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF16 RTBV_P46 PF06216.6 CCD26589.1 - 0.018 13.8 0.7 0.024 13.5 0.5 1.2 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF3416 PF11896.3 CCD26589.1 - 0.021 14.8 0.3 0.027 14.4 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3416) IncA PF04156.9 CCD26589.1 - 0.033 13.7 3.9 0.055 13.0 2.7 1.4 1 0 0 1 1 1 0 IncA protein ALIX_LYPXL_bnd PF13949.1 CCD26589.1 - 0.043 12.7 4.4 0.019 13.9 1.3 1.6 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV DUF3450 PF11932.3 CCD26589.1 - 0.06 12.5 1.0 0.09 12.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1395 PF07160.7 CCD26589.1 - 0.092 12.2 3.0 0.95 8.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1395) Complex1_49kDa PF00346.14 CCD26589.1 - 0.11 11.5 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit DUF3373 PF11853.3 CCD26589.1 - 0.12 10.8 0.4 0.13 10.7 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) PFEMP PF03011.10 CCD26589.1 - 0.13 12.6 6.5 0.077 13.3 2.4 1.9 2 0 0 2 2 2 0 PFEMP DBL domain FlaC_arch PF05377.6 CCD26589.1 - 0.13 12.1 4.3 0.73 9.7 3.0 2.1 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DegS PF05384.6 CCD26589.1 - 0.16 11.1 3.6 0.25 10.5 1.5 1.9 1 1 1 2 2 2 0 Sensor protein DegS NPV_P10 PF05531.7 CCD26589.1 - 0.66 10.2 6.1 2.5 8.3 3.3 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein CCDC-167 PF15188.1 CCD26589.1 - 0.82 9.6 4.9 0.6 10.0 1.7 2.0 2 1 1 3 3 2 0 Coiled-coil domain-containing protein 167 TSC22 PF01166.13 CCD26589.1 - 4 7.4 6.9 1.6 8.7 1.3 2.6 2 1 1 3 3 2 0 TSC-22/dip/bun family zf-LYAR PF08790.6 CCD26590.1 - 2.2e-15 56.0 7.3 4.8e-15 54.9 5.1 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf-TRAF PF02176.13 CCD26590.1 - 0.13 12.6 2.8 0.24 11.7 2.0 1.5 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_4 PF13894.1 CCD26590.1 - 0.38 11.2 4.0 35 5.0 2.8 2.5 1 1 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCD26590.1 - 0.53 10.5 6.2 0.69 10.1 0.6 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding A2L_zn_ribbon PF08792.5 CCD26590.1 - 0.82 9.2 8.8 25 4.4 6.1 2.8 1 1 0 1 1 1 0 A2L zinc ribbon domain XPA_N PF01286.13 CCD26590.1 - 0.96 9.1 5.2 5.4 6.7 0.2 2.3 2 0 0 2 2 2 0 XPA protein N-terminal RNHCP PF12647.2 CCD26590.1 - 1.2 8.9 4.7 3.3 7.5 3.3 1.9 1 1 0 1 1 1 0 RNHCP domain DUF1510 PF07423.6 CCD26590.1 - 1.3 8.3 14.7 1.8 7.8 10.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 CCD26590.1 - 1.4 8.0 5.9 1.6 7.8 4.1 1.0 1 0 0 1 1 1 0 Putative metallopeptidase domain zf-C2H2 PF00096.21 CCD26590.1 - 1.4 9.4 6.4 0.79 10.1 0.7 2.6 1 1 1 2 2 2 0 Zinc finger, C2H2 type UPF0560 PF10577.4 CCD26590.1 - 1.4 7.0 8.7 1.7 6.8 6.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 zf-C2H2_6 PF13912.1 CCD26590.1 - 1.5 8.8 6.3 0.81 9.6 1.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Neur_chan_memb PF02932.11 CCD26590.1 - 1.5 8.6 4.1 1.6 8.5 2.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region C1_4 PF07975.7 CCD26590.1 - 2.9 7.9 9.4 1.1 9.2 3.6 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain Cofilin_ADF PF00241.15 CCD26591.1 - 6e-27 94.0 0.2 1.1e-25 89.9 0.0 2.3 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.23 CCD26591.1 - 2.8e-15 55.4 1.1 7.1e-15 54.1 0.8 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCD26591.1 - 2.3e-14 52.6 0.4 5.2e-14 51.5 0.3 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCD26591.1 - 5.4e-06 25.7 0.0 1.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Flocculin_t3 PF13928.1 CCD26592.1 - 1.2e-07 31.7 51.2 2.2e-05 24.5 8.4 25.1 14 8 7 21 21 21 6 Flocculin type 3 repeat DUF866 PF05907.8 CCD26593.1 - 2.2e-27 95.5 3.4 2.2e-13 50.0 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) GFA PF04828.9 CCD26593.1 - 0.12 12.3 1.4 1 9.3 0.1 2.5 2 2 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Baculo_ME53 PF06061.6 CCD26593.1 - 0.42 9.5 0.1 0.42 9.5 0.0 2.5 2 2 1 3 3 3 0 Baculoviridae ME53 Pkinase PF00069.20 CCD26594.1 - 2.2e-72 243.3 1.1 7.2e-72 241.6 0.8 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26594.1 - 4.2e-32 111.2 0.1 2.2e-29 102.3 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD26594.1 - 1e-08 34.5 2.1 1.2e-06 27.7 0.1 3.6 2 1 1 3 3 3 1 Kinase-like Yeast-kill-tox PF09207.6 CCD26594.1 - 0.026 14.9 0.9 0.099 13.0 0.0 2.3 2 0 0 2 2 2 0 Yeast killer toxin MCR_beta PF02241.13 CCD26594.1 - 0.15 11.2 0.0 0.31 10.2 0.0 1.4 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain MutS_V PF00488.16 CCD26595.1 - 2.3e-74 249.7 0.1 1.2e-73 247.4 0.0 2.3 3 0 0 3 3 3 1 MutS domain V MutS_III PF05192.13 CCD26595.1 - 8.1e-32 110.6 2.0 9.2e-32 110.4 0.3 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 CCD26595.1 - 2.6e-29 101.5 0.6 6.3e-29 100.2 0.1 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 CCD26595.1 - 1.9e-11 43.9 3.2 7.1e-11 42.1 2.2 2.1 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 CCD26595.1 - 3e-06 27.3 1.4 9.6e-06 25.7 0.0 2.6 3 1 0 3 3 3 1 MutS domain II DUF940 PF06082.6 CCD26595.1 - 7.6 4.9 8.5 11 4.3 5.9 1.2 1 0 0 1 1 1 0 Bacterial putative lipoprotein (DUF940) Not1 PF04054.10 CCD26596.1 - 5.9e-137 456.5 4.9 5.9e-137 456.5 3.4 3.9 4 0 0 4 4 4 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CCD26596.1 - 2.7e-43 147.1 7.2 2.1e-42 144.2 5.0 2.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CDC50 PF03381.10 CCD26597.1 - 3.6e-93 311.7 0.2 4.4e-93 311.4 0.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Y_phosphatase2 PF03162.8 CCD26598.1 - 1.3e-32 112.4 12.8 1.3e-23 83.1 1.8 2.8 3 0 0 3 3 3 2 Tyrosine phosphatase family DUF2665 PF11654.3 CCD26599.1 - 5.2e-13 48.3 0.2 7.2e-13 47.8 0.1 1.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2665) PI31_Prot_C PF08577.6 CCD26600.1 - 1.4e-11 44.8 6.5 3.6e-11 43.5 4.5 1.7 1 0 0 1 1 1 1 PI31 proteasome regulator DUF3215 PF11503.3 CCD26601.1 - 7.1e-18 64.0 0.0 8.8e-18 63.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) PQ-loop PF04193.9 CCD26602.1 - 1.4e-22 79.0 17.2 8.5e-15 54.0 0.6 3.4 3 0 0 3 3 3 2 PQ loop repeat TMEM238 PF15125.1 CCD26602.1 - 1.6 8.7 5.9 0.93 9.4 0.3 3.1 3 0 0 3 3 3 0 TMEM238 protein family Pkinase PF00069.20 CCD26603.1 - 1.6e-62 211.0 0.0 5.3e-62 209.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26603.1 - 2.4e-34 118.5 0.0 7.7e-34 116.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD26603.1 - 1e-07 31.2 0.0 2.4e-06 26.7 0.0 2.8 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 CCD26603.1 - 0.093 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 CCD26604.1 - 9.9e-85 275.7 31.5 9e-16 57.0 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 CCD26604.1 - 2.9e-08 33.6 0.4 0.00027 20.7 0.0 3.3 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 CCD26604.1 - 4.4e-07 29.8 0.0 8.1e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CCD26604.1 - 3.5e-06 25.4 10.0 0.19 9.8 0.3 5.0 3 3 2 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCD26604.1 - 0.00035 19.4 0.5 1.3 7.7 0.0 3.2 2 1 1 3 3 3 2 Nup133 N terminal like Nbas_N PF15492.1 CCD26604.1 - 0.0065 15.6 0.4 0.62 9.1 0.1 2.5 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.4 CCD26604.1 - 0.02 14.3 0.1 0.095 12.0 0.0 2.0 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain Apc4_WD40 PF12894.2 CCD26604.1 - 0.043 13.3 0.0 0.19 11.2 0.0 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain Img2 PF05046.9 CCD26605.1 - 7.8e-29 99.7 0.6 1.3e-28 99.0 0.4 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 CCD26605.1 - 0.0073 16.0 1.0 0.024 14.4 0.7 2.0 1 1 0 1 1 1 1 Translation initiation factor SUI1 DUF3294 PF07957.6 CCD26605.1 - 0.052 13.0 0.1 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3294) Pro_isomerase PF00160.16 CCD26606.1 - 1.7e-23 83.5 0.0 2.9e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lipase_3 PF01764.20 CCD26607.1 - 6.2e-10 38.8 0.0 1.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CCD26607.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 CCD26607.1 - 0.022 14.4 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 CCD26607.1 - 0.052 13.3 0.0 0.1 12.3 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 CCD26607.1 - 0.079 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein WD40 PF00400.27 CCD26608.1 - 4e-07 29.6 0.3 0.00036 20.2 0.1 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCD26608.1 - 0.0067 15.9 0.0 0.016 14.7 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4 PF00097.20 CCD26609.1 - 3.9e-11 42.4 11.2 3.9e-11 42.4 7.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD26609.1 - 1.4e-10 40.9 11.6 1.4e-10 40.9 8.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.22 CCD26609.1 - 9e-10 37.8 0.0 2.2e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.1 CCD26609.1 - 2e-09 37.1 14.4 8.3e-09 35.1 7.3 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCD26609.1 - 8.3e-09 34.9 10.9 4.1e-08 32.7 4.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCD26609.1 - 6e-08 32.4 15.3 1.1e-07 31.6 7.9 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCD26609.1 - 1.9e-07 30.7 16.0 1.1e-06 28.2 7.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 CCD26609.1 - 2.3e-07 30.5 4.0 2.3e-07 30.5 2.8 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CCD26609.1 - 5e-06 26.1 7.8 5e-06 26.1 5.4 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 CCD26609.1 - 0.00018 21.5 4.0 0.00018 21.5 2.8 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 CCD26609.1 - 0.0016 18.3 0.1 0.0068 16.3 0.0 2.1 2 0 0 2 2 2 1 U-box domain Alpha_L_fucos PF01120.12 CCD26609.1 - 0.04 12.8 0.7 0.081 11.8 0.1 1.6 1 1 1 2 2 2 0 Alpha-L-fucosidase zf-Nse PF11789.3 CCD26609.1 - 0.055 12.9 10.8 0.075 12.5 4.0 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 CCD26609.1 - 0.61 9.9 3.6 0.58 10.0 0.8 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 CCD26609.1 - 1.1 8.7 8.1 7.1 6.1 0.0 3.9 3 1 0 3 3 3 0 Rad50 zinc hook motif DUF1272 PF06906.6 CCD26609.1 - 1.2 9.0 6.8 4 7.3 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) zf-RING_4 PF14570.1 CCD26609.1 - 1.3 8.6 11.5 1.7 8.2 4.6 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CCD26609.1 - 1.5 8.4 9.2 0.24 10.9 2.5 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Fork_head PF00250.13 CCD26610.1 - 2e-34 117.5 3.2 2.1e-34 117.4 0.2 2.6 3 0 0 3 3 3 1 Fork head domain G10 PF01125.12 CCD26611.1 - 2.4e-61 205.5 8.9 2.7e-61 205.3 6.1 1.0 1 0 0 1 1 1 1 G10 protein Ytp1 PF10355.4 CCD26612.1 - 3.6e-106 354.3 12.7 5.4e-106 353.7 8.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CCD26612.1 - 2e-26 91.5 5.7 2e-26 91.5 4.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) CcmD PF04995.9 CCD26612.1 - 9.1 6.1 6.3 0.81 9.4 0.2 2.4 3 0 0 3 3 3 0 Heme exporter protein D (CcmD) TPR_11 PF13414.1 CCD26613.1 - 2.3e-15 55.9 0.0 4e-15 55.2 0.0 1.3 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 CCD26613.1 - 7e-10 38.0 0.5 0.00033 20.1 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 CCD26613.1 - 7.8e-10 37.9 0.1 3.9e-05 23.2 0.1 2.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCD26613.1 - 1.3e-05 24.6 0.2 0.013 15.2 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCD26613.1 - 6.8e-05 22.7 0.2 0.00068 19.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCD26613.1 - 0.00018 21.3 0.0 0.0013 18.5 0.0 1.9 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCD26613.1 - 0.00049 20.6 0.0 0.00098 19.7 0.0 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCD26613.1 - 0.0017 18.0 0.0 0.076 12.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCD26613.1 - 0.0018 18.5 0.0 0.0032 17.7 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCD26613.1 - 0.0038 17.5 0.1 0.29 11.6 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 CCD26613.1 - 0.015 15.0 0.3 0.027 14.2 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCD26613.1 - 0.033 14.0 0.1 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 CCD26613.1 - 0.035 14.7 0.0 0.75 10.6 0.0 2.4 2 1 1 3 3 2 0 Tetratricopeptide repeat MIT PF04212.13 CCD26613.1 - 0.085 12.7 1.7 5.8 6.8 0.0 2.7 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain SR-25 PF10500.4 CCD26613.1 - 0.1 12.0 4.3 0.12 11.8 3.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AdoMetDC_leader PF08132.6 CCD26613.1 - 0.16 11.9 3.1 0.29 11.0 0.6 2.3 3 0 0 3 3 3 0 S-adenosyl-l-methionine decarboxylase leader peptide UPF0029 PF01205.14 CCD26614.1 - 4.3e-30 103.6 0.1 5.9e-30 103.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 CCD26614.1 - 2.4e-09 37.0 0.7 4.1e-09 36.3 0.5 1.4 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.21 CCD26614.1 - 0.067 12.6 0.1 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-conjugating enzyme WD40 PF00400.27 CCD26615.1 - 2.4e-54 179.3 19.7 3.1e-13 49.0 0.1 12.2 12 0 0 12 12 12 7 WD domain, G-beta repeat Utp12 PF04003.7 CCD26615.1 - 5.9e-27 93.7 0.0 9.5e-27 93.0 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 CCD26615.1 - 6e-08 32.6 9.2 0.00018 21.2 0.3 6.1 5 1 2 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CCD26615.1 - 0.0016 17.5 0.2 2.5 7.1 0.0 3.8 3 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Apc4_WD40 PF12894.2 CCD26615.1 - 0.0067 15.9 0.0 3.5 7.1 0.0 3.6 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Atx10homo_assoc PF09759.4 CCD26616.1 - 7.9e-38 128.2 1.6 1.8e-37 127.1 0.2 2.3 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Thr_synth_N PF14821.1 CCD26617.1 - 3.6e-29 100.5 0.0 1.4e-28 98.7 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 CCD26617.1 - 1.8e-20 73.3 0.0 2.6e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4094 PF13334.1 CCD26618.1 - 5.8 7.3 7.5 0.97 9.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) DUF1682 PF07946.9 CCD26619.1 - 2.6e-72 243.3 10.5 3.2e-72 243.0 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4375 PF14300.1 CCD26619.1 - 0.0091 15.9 3.4 0.0091 15.9 2.4 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4375) RNase_H2-Ydr279 PF09468.5 CCD26619.1 - 4.2 6.4 18.0 15 4.6 0.1 2.9 3 0 0 3 3 3 0 Ydr279p protein family (RNase H2 complex component) Ank_5 PF13857.1 CCD26620.1 - 5.8e-16 58.1 0.0 1.6e-12 47.2 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCD26620.1 - 1.1e-10 41.6 0.0 2.4e-09 37.4 0.0 2.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCD26620.1 - 6.3e-10 39.2 0.1 2.5e-08 34.1 0.0 3.3 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank PF00023.25 CCD26620.1 - 1.4e-09 37.2 2.7 4.2e-07 29.4 0.1 3.5 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CCD26620.1 - 3.5e-08 32.9 0.0 0.00013 21.8 0.0 4.3 5 0 0 5 5 5 1 Ankyrin repeat Inositol_P PF00459.20 CCD26620.1 - 0.022 14.0 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family DUF3786 PF12654.2 CCD26620.1 - 0.11 11.8 0.0 1.6 8.0 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF3786) MBOAT PF03062.14 CCD26621.1 - 2.3e-42 145.2 36.8 1.6e-35 122.8 15.2 2.3 1 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Ashwin PF15323.1 CCD26621.1 - 0.16 11.9 11.7 0.28 11.1 8.1 1.4 1 0 0 1 1 1 0 Developmental protein MBOAT_2 PF13813.1 CCD26621.1 - 0.16 12.0 8.8 0.35 10.9 6.1 1.6 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family Wbp11 PF09429.5 CCD26621.1 - 0.4 10.6 3.1 0.25 11.3 0.2 2.1 2 0 0 2 2 2 0 WW domain binding protein 11 WBS_methylT PF12589.3 CCD26622.1 - 1.4e-17 63.9 6.8 3.1e-17 62.8 4.7 1.6 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 CCD26622.1 - 2.1e-12 47.3 0.0 5.3e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCD26622.1 - 3.8e-08 33.0 0.0 8.9e-08 31.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCD26622.1 - 1.8e-07 31.0 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD26622.1 - 7e-07 29.5 0.0 2.7e-06 27.6 0.0 2.0 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCD26622.1 - 2.8e-06 27.7 0.1 1.7e-05 25.2 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD26622.1 - 7.7e-06 26.4 0.0 3.1e-05 24.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCD26622.1 - 0.00034 20.6 0.0 0.00077 19.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CCD26622.1 - 0.00057 19.3 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 CCD26622.1 - 0.00076 19.0 0.0 0.0034 16.9 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 CCD26622.1 - 0.0025 16.9 0.0 0.012 14.7 0.0 1.9 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase N6_N4_Mtase PF01555.13 CCD26622.1 - 0.0075 15.7 0.1 1.3 8.4 0.0 2.2 2 0 0 2 2 2 1 DNA methylase PrmA PF06325.8 CCD26622.1 - 0.016 14.3 0.2 0.047 12.8 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) FACT-Spt16_Nlob PF14826.1 CCD26622.1 - 0.16 11.5 0.9 0.29 10.6 0.5 1.5 1 1 0 1 1 1 0 FACT complex subunit SPT16 N-terminal lobe domain ADH_zinc_N PF00107.21 CCD26623.1 - 1e-14 54.2 0.0 2.1e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCD26623.1 - 0.00099 18.8 0.4 0.017 14.8 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Ribosomal_L19 PF01245.15 CCD26624.1 - 2.4e-12 46.6 0.2 3.3e-12 46.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 Peptidase_S8 PF00082.17 CCD26625.1 - 2.4e-41 141.7 0.5 3.5e-41 141.2 0.3 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CCD26625.1 - 6.8e-05 23.3 0.1 0.00017 22.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase inhibitor I9 ACC_central PF08326.7 CCD26626.1 - 7.1e-260 864.0 0.1 9e-260 863.7 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 CCD26626.1 - 3.6e-177 589.6 0.0 5.4e-177 589.0 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CCD26626.1 - 4.9e-51 173.0 0.0 1.1e-50 171.9 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CCD26626.1 - 4.1e-27 94.4 0.1 9e-27 93.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCD26626.1 - 2.5e-20 72.4 0.0 1.3e-19 70.1 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CCD26626.1 - 6e-19 67.4 0.3 1.5e-18 66.2 0.2 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CCD26626.1 - 3.6e-09 36.6 0.0 9.5e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCD26626.1 - 9.7e-09 34.4 0.0 0.0046 15.7 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 CCD26626.1 - 0.00022 20.8 0.2 0.023 14.3 0.0 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 CCD26626.1 - 0.0024 17.3 0.0 0.0064 15.9 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RnfC_N PF13375.1 CCD26626.1 - 0.023 14.4 0.1 0.078 12.6 0.0 1.9 2 0 0 2 2 1 0 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.9 CCD26626.1 - 0.028 14.2 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain ATP-grasp PF02222.17 CCD26626.1 - 0.085 12.2 0.0 0.31 10.3 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain Indigoidine_A PF04227.7 CCD26627.1 - 0.8 8.8 4.2 0.46 9.6 0.0 2.2 2 0 0 2 2 2 0 Indigoidine synthase A like protein PFK PF00365.15 CCD26628.1 - 8e-167 553.2 0.8 8.5e-124 412.0 1.6 2.1 2 0 0 2 2 2 2 Phosphofructokinase Inp1 PF12634.2 CCD26629.1 - 3.8e-37 127.1 0.1 3.8e-37 127.1 0.1 2.6 3 1 1 4 4 4 1 Inheritance of peroxisomes protein 1 Porin_3 PF01459.17 CCD26630.1 - 6.2e-82 274.9 0.1 7.3e-82 274.7 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin ERG2_Sigma1R PF04622.7 CCD26631.1 - 3.8e-88 294.3 2.0 4.6e-88 294.0 1.4 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein XPA_C PF05181.7 CCD26632.1 - 2.5e-27 94.2 0.2 6e-27 92.9 0.2 1.7 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.13 CCD26632.1 - 0.0021 17.6 0.3 0.0046 16.6 0.2 1.5 1 0 0 1 1 1 1 XPA protein N-terminal DUF2762 PF10960.3 CCD26632.1 - 5.5 6.7 10.1 0.82 9.4 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) Rot1 PF10681.4 CCD26633.1 - 6e-96 319.8 0.3 6.9e-96 319.6 0.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal ATG16 PF08614.6 CCD26634.1 - 0.0021 17.8 8.5 0.0021 17.8 5.9 4.2 2 2 2 4 4 4 2 Autophagy protein 16 (ATG16) DUF3373 PF11853.3 CCD26634.1 - 1.8 7.0 12.9 2 6.8 7.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) NPV_P10 PF05531.7 CCD26634.1 - 4.8 7.5 31.0 0.7 10.1 2.1 5.2 3 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein V-SNARE_C PF12352.3 CCD26635.1 - 3.9e-20 71.6 2.5 3.9e-20 71.6 1.7 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 CCD26635.1 - 1.6e-15 56.9 4.4 1.6e-15 56.9 3.1 2.3 2 1 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus Sec20 PF03908.8 CCD26635.1 - 0.13 11.9 7.1 0.063 12.9 1.6 2.4 2 1 0 2 2 2 0 Sec20 YqjK PF13997.1 CCD26635.1 - 0.6 10.3 2.9 0.95 9.6 0.0 2.5 3 0 0 3 3 3 0 YqjK-like protein FliJ PF02050.11 CCD26635.1 - 4 7.5 11.6 1 9.4 1.3 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein Glyco_hydro_63 PF03200.11 CCD26636.1 - 9.1e-07 27.1 13.7 5.8e-06 24.4 0.9 4.3 4 1 0 4 4 4 3 Mannosyl oligosaccharide glucosidase DUF1903 PF08991.5 CCD26638.1 - 2e-21 75.9 3.8 2.3e-21 75.6 2.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 CCD26638.1 - 0.0019 18.0 3.6 0.0019 18.0 2.5 2.0 2 0 0 2 2 2 1 CHCH domain Cmc1 PF08583.5 CCD26638.1 - 0.019 14.7 2.0 0.027 14.2 1.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 CCD26638.1 - 0.088 12.8 2.4 0.088 12.8 1.6 1.9 2 0 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Ribosomal_L36e PF01158.13 CCD26639.1 - 1.1e-37 127.8 4.4 1.3e-37 127.7 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e Ribosomal_L28 PF00830.14 CCD26640.1 - 3.3e-22 78.0 0.8 7.8e-22 76.8 0.6 1.7 1 0 0 1 1 1 1 Ribosomal L28 family RabGAP-TBC PF00566.13 CCD26641.1 - 9.5e-24 84.0 0.7 9.5e-24 84.0 0.5 2.4 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DDE_Tnp_1_5 PF13737.1 CCD26642.1 - 0.0051 16.9 0.1 0.22 11.6 0.0 2.3 2 0 0 2 2 2 1 Transposase DDE domain DUF3638 PF12340.3 CCD26642.1 - 0.04 12.8 0.1 0.074 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) Fungal_trans PF04082.13 CCD26643.1 - 2.3e-22 79.1 10.1 2.3e-22 79.1 7.0 3.4 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD26643.1 - 1.7e-10 40.6 11.8 3.3e-10 39.7 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 CCD26643.1 - 8.8e-09 35.1 0.2 2.7e-08 33.6 0.1 1.9 1 0 0 1 1 1 1 Gal4-like dimerisation domain Helicase_Sgs1 PF11408.3 CCD26644.1 - 4.2e-26 90.5 0.1 2.1e-25 88.3 0.1 2.4 1 0 0 1 1 1 1 Sgs1 RecQ helicase RQC PF09382.5 CCD26644.1 - 2.6e-21 75.3 0.5 8.5e-21 73.6 0.3 1.9 2 0 0 2 2 2 1 RQC domain DEAD PF00270.24 CCD26644.1 - 2.8e-21 75.7 0.3 1.3e-20 73.5 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD26644.1 - 2.3e-20 72.2 0.0 2.8e-19 68.7 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.18 CCD26644.1 - 0.0086 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 HRDC domain NUDIX PF00293.23 CCD26645.1 - 7.5e-12 45.0 0.0 2e-11 43.6 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain zf-NADH-PPase PF09297.6 CCD26645.1 - 8.9e-05 21.9 0.3 0.0002 20.8 0.0 1.7 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain DUF3323 PF11796.3 CCD26645.1 - 0.17 11.2 0.0 0.3 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) NUDIX-like PF09296.6 CCD26645.1 - 0.18 12.1 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 NADH pyrophosphatase-like rudimentary NUDIX domain SCA7 PF08313.7 CCD26646.1 - 8e-34 115.0 1.5 8e-34 115.0 1.1 2.9 3 0 0 3 3 3 1 SCA7, zinc-binding domain Nucleoplasmin PF03066.10 CCD26646.1 - 2.2 7.7 22.5 0.036 13.5 10.1 2.1 2 0 0 2 2 2 0 Nucleoplasmin Glycos_transf_1 PF00534.15 CCD26647.1 - 2.1e-33 115.1 0.0 3.1e-33 114.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCD26647.1 - 5.1e-07 29.5 0.0 1.8e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CCD26647.1 - 0.0016 18.5 0.0 0.0061 16.7 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCD26647.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain DEAD PF00270.24 CCD26648.1 - 5.7e-31 107.2 0.1 1.4e-30 105.9 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD26648.1 - 2.1e-13 49.9 0.4 1.9e-12 46.8 0.1 2.6 2 1 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCD26648.1 - 6.3e-08 31.7 0.3 1.1e-07 30.9 0.2 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 CCD26648.1 - 2.4e-06 27.5 0.0 2.4e-06 27.5 0.0 2.7 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCD26648.1 - 0.0081 16.3 0.2 0.069 13.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain CobA_CobO_BtuR PF02572.10 CCD26648.1 - 0.023 14.2 0.1 0.88 9.1 0.0 2.4 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Hyphal_reg_CWP PF11765.3 CCD26649.1 - 1.7e-46 158.5 16.7 1.7e-46 158.5 11.6 3.4 3 1 0 3 3 3 1 Hyphally regulated cell wall protein N-terminal PseudoU_synth_1 PF01416.15 CCD26650.1 - 8e-20 71.2 0.0 6.1e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase DAP3 PF10236.4 CCD26651.1 - 5.9e-80 268.4 0.2 7.9e-80 268.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CCD26651.1 - 8.8e-06 25.8 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CCD26651.1 - 0.007 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCD26651.1 - 0.012 15.7 0.0 0.025 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CCD26651.1 - 0.024 14.3 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 CCD26651.1 - 0.028 14.3 0.1 0.1 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCD26651.1 - 0.098 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 CCD26651.1 - 0.11 11.2 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 CCD26651.1 - 0.13 11.9 0.0 0.56 9.8 0.0 2.1 3 0 0 3 3 3 0 NACHT domain IstB_IS21 PF01695.12 CCD26651.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 CCD26651.1 - 0.15 11.1 0.0 0.35 9.9 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 CCD26651.1 - 0.18 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain mRNA_cap_enzyme PF01331.14 CCD26652.1 - 9e-55 185.3 1.5 1.5e-54 184.6 0.5 1.7 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CCD26652.1 - 1.2e-22 80.2 1.9 1e-21 77.1 0.5 2.5 2 1 0 2 2 2 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 CCD26652.1 - 8e-09 35.1 0.1 6e-08 32.2 0.1 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_OB PF03120.11 CCD26652.1 - 0.035 13.7 0.1 0.064 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain BAH PF01426.13 CCD26653.1 - 1e-14 54.2 0.1 1e-14 54.2 0.1 2.5 3 0 0 3 3 3 1 BAH domain PHD PF00628.24 CCD26653.1 - 1.1e-14 53.7 53.8 7.4e-08 31.9 9.3 5.0 5 0 0 5 5 5 3 PHD-finger zf-HC5HC2H_2 PF13832.1 CCD26653.1 - 3e-13 49.7 16.8 5.9e-13 48.7 5.7 5.0 6 0 0 6 6 6 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CCD26653.1 - 6.2e-10 39.0 36.3 3.2e-08 33.5 4.8 4.7 4 0 0 4 4 4 3 PHD-like zinc-binding domain PHD_2 PF13831.1 CCD26653.1 - 1.2e-05 24.5 28.7 0.00035 19.8 4.8 4.9 3 1 0 3 3 3 3 PHD-finger Myb_DNA-binding PF00249.26 CCD26653.1 - 0.00042 20.3 0.0 0.0013 18.7 0.0 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain C1_1 PF00130.17 CCD26653.1 - 0.0048 16.5 2.7 0.0048 16.5 1.9 5.4 5 0 0 5 5 5 3 Phorbol esters/diacylglycerol binding domain (C1 domain) WAC_Acf1_DNA_bd PF10537.4 CCD26654.1 - 1.3e-36 124.8 0.6 1.3e-36 124.8 0.4 2.4 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CCD26654.1 - 1.8e-13 50.0 1.8 1.3e-12 47.3 0.4 2.7 3 0 0 3 3 3 1 DDT domain WHIM2 PF15613.1 CCD26654.1 - 1.8e-09 37.1 0.2 4.4e-09 35.9 0.2 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 CCD26654.1 - 0.0018 18.1 0.8 0.0051 16.6 0.0 2.2 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 Cyclin PF08613.6 CCD26655.1 - 1.9e-16 60.8 1.5 4.8e-16 59.5 1.1 1.7 1 0 0 1 1 1 1 Cyclin PMBR PF09373.5 CCD26655.1 - 0.0086 15.9 0.0 2.1 8.4 0.0 3.1 2 0 0 2 2 2 2 Pseudomurein-binding repeat FtsJ PF01728.14 CCD26656.1 - 3.6e-55 186.7 0.0 4.7e-55 186.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 CCD26656.1 - 0.00053 19.7 0.0 0.0033 17.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCD26656.1 - 0.00095 18.7 0.0 0.61 9.6 0.1 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 CCD26656.1 - 0.0032 18.0 0.0 0.012 16.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Coatomer_WDAD PF04053.9 CCD26657.1 - 1.5e-141 472.1 0.4 1.5e-141 472.1 0.3 1.8 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 CCD26657.1 - 1.8e-45 151.2 6.4 9e-12 44.3 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CCD26657.1 - 0.0003 19.0 3.0 0.007 14.5 0.1 3.1 3 1 0 4 4 4 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 CCD26657.1 - 0.00093 18.9 0.0 5.9 6.7 0.0 4.8 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region MIT PF04212.13 CCD26657.1 - 0.0032 17.3 0.5 0.18 11.7 0.0 3.2 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 CCD26657.1 - 0.054 13.1 2.3 2.9 7.6 0.7 3.2 2 1 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 CCD26657.1 - 0.33 10.6 3.0 35 4.2 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TRP PF06011.7 CCD26659.1 - 1.5e-147 491.7 37.9 2.5e-147 490.9 26.3 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCD26659.1 - 8.1e-45 152.3 1.1 1.5e-44 151.4 0.8 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 CCD26659.1 - 0.00054 20.2 0.1 0.00095 19.4 0.1 1.4 1 0 0 1 1 1 1 ML domain PgaD PF13994.1 CCD26659.1 - 5.8 6.3 11.5 0.17 11.3 0.6 2.9 2 1 1 3 3 3 0 PgaD-like protein GCR1_C PF12550.3 CCD26660.1 - 2.7e-23 81.6 2.9 6.8e-23 80.3 2.0 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Nop14 PF04147.7 CCD26660.1 - 0.00083 17.4 43.6 0.00083 17.4 30.2 2.4 2 0 0 2 2 2 1 Nop14-like family ARID PF01388.16 CCD26662.1 - 1e-21 76.5 0.1 4.8e-21 74.4 0.1 2.3 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjC PF02373.17 CCD26662.1 - 2.9e-14 53.2 8.3 3e-07 30.6 0.1 3.5 3 1 1 4 4 4 2 JmjC domain, hydroxylase PHD PF00628.24 CCD26662.1 - 2.9e-07 30.0 6.3 5.8e-07 29.1 4.4 1.5 1 0 0 1 1 1 1 PHD-finger JmjN PF02375.12 CCD26662.1 - 0.0085 15.5 0.0 0.024 14.1 0.0 1.8 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 CCD26662.1 - 0.075 13.1 4.9 0.24 11.5 3.4 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.17 CCD26662.1 - 0.53 10.0 4.4 1.4 8.7 3.0 1.6 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cation_efflux PF01545.16 CCD26663.1 - 9.1e-44 149.6 9.5 1.9e-43 148.5 6.6 1.5 1 1 0 1 1 1 1 Cation efflux family Polysacc_synt_4 PF04669.8 CCD26664.1 - 5.2e-23 81.3 3.1 3.2e-22 78.8 2.2 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis BCS1_N PF08740.6 CCD26664.1 - 0.065 12.8 0.1 0.07 12.7 0.0 1.1 1 0 0 1 1 1 0 BCS1 N terminal ABC_tran PF00005.22 CCD26665.1 - 9.1e-49 165.2 0.0 1e-25 90.6 0.0 4.2 3 2 0 3 3 3 2 ABC transporter SMC_N PF02463.14 CCD26665.1 - 6.1e-13 48.5 0.0 0.00094 18.4 0.0 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCD26665.1 - 2.3e-11 44.2 15.3 0.00026 21.0 0.2 4.9 4 2 0 5 5 3 3 AAA domain Chromo PF00385.19 CCD26665.1 - 5.2e-10 38.8 1.3 1.3e-09 37.5 0.9 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 CCD26665.1 - 4e-08 32.6 0.2 0.01 15.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 CCD26665.1 - 3e-07 30.1 0.3 0.25 10.7 0.0 4.3 4 1 0 4 4 4 2 AAA-like domain AAA_17 PF13207.1 CCD26665.1 - 4e-07 30.8 0.1 0.067 14.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 CCD26665.1 - 3.3e-06 27.0 0.0 0.041 13.8 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 CCD26665.1 - 3.8e-06 26.1 0.0 0.013 14.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCD26665.1 - 6.4e-06 26.3 0.1 0.096 12.8 0.0 3.8 3 0 0 3 3 3 2 AAA domain Miro PF08477.8 CCD26665.1 - 2.8e-05 24.5 0.0 0.11 12.9 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA PF00004.24 CCD26665.1 - 9.3e-05 22.6 0.1 3.6 7.7 0.0 4.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 CCD26665.1 - 0.00011 22.6 0.0 0.0055 17.0 0.0 4.6 4 1 1 5 5 3 2 AAA domain ArgK PF03308.11 CCD26665.1 - 0.00013 20.8 0.2 0.5 9.1 0.0 2.6 2 0 0 2 2 2 2 ArgK protein DUF87 PF01935.12 CCD26665.1 - 0.00018 21.3 4.8 0.037 13.8 0.0 4.5 4 0 0 4 4 4 1 Domain of unknown function DUF87 AAA_33 PF13671.1 CCD26665.1 - 0.00034 20.5 0.0 0.9 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CCD26665.1 - 0.00047 19.8 0.0 0.29 10.8 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 CCD26665.1 - 0.00054 20.1 0.0 1.4 9.1 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 CCD26665.1 - 0.00061 20.1 0.2 0.41 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CCD26665.1 - 0.00062 19.7 0.0 0.39 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 CCD26665.1 - 0.00064 19.5 0.3 1.9 8.4 0.0 3.9 2 2 1 3 3 3 1 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 CCD26665.1 - 0.00091 18.9 0.9 0.85 9.2 0.0 3.0 3 0 0 3 3 3 2 NACHT domain Dynamin_N PF00350.18 CCD26665.1 - 0.0012 18.6 0.1 0.29 10.9 0.0 3.6 2 1 1 3 3 3 1 Dynamin family AAA_30 PF13604.1 CCD26665.1 - 0.0023 17.5 1.2 2.7 7.5 0.2 3.4 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 CCD26665.1 - 0.0061 16.5 0.3 0.71 9.8 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.8 CCD26665.1 - 0.0093 14.9 0.0 2.5 6.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 CCD26665.1 - 0.011 15.6 0.1 3.2 7.6 0.0 3.3 3 0 0 3 3 2 0 AAA domain Zeta_toxin PF06414.7 CCD26665.1 - 0.011 14.8 0.4 3.9 6.5 0.0 3.1 4 0 0 4 4 4 0 Zeta toxin FtsK_SpoIIIE PF01580.13 CCD26665.1 - 0.014 14.8 0.1 2.9 7.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family Ipi1_N PF12333.3 CCD26665.1 - 0.017 15.0 0.2 0.17 11.8 0.0 2.9 3 0 0 3 3 2 0 Rix1 complex component involved in 60S ribosome maturation AAA_25 PF13481.1 CCD26665.1 - 0.048 13.0 0.0 11 5.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain MutS_V PF00488.16 CCD26665.1 - 0.13 11.6 0.1 12 5.1 0.0 2.3 2 0 0 2 2 2 0 MutS domain V AbfB PF05270.8 CCD26667.1 - 0.02 14.6 1.3 0.044 13.4 0.9 1.7 1 1 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) zf-H2C2_2 PF13465.1 CCD26668.1 - 2.9e-09 36.7 1.2 2.9e-09 36.7 0.9 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCD26668.1 - 3.8e-09 36.3 8.5 0.00037 20.6 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD26668.1 - 1.4e-08 34.4 7.7 0.00035 20.7 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 CCD26668.1 - 0.0041 17.2 4.7 0.056 13.6 0.3 2.8 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_6 PF13912.1 CCD26668.1 - 0.28 11.1 1.7 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 CCD26668.1 - 0.4 10.9 7.3 1.6 9.0 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type LMBR1 PF04791.11 CCD26668.1 - 0.57 8.6 2.3 0.78 8.2 1.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein SNARE PF05739.14 CCD26669.1 - 1.4e-15 56.7 8.7 1.4e-15 56.7 6.0 2.6 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CCD26669.1 - 0.00023 21.2 12.8 0.00023 21.2 8.9 3.2 3 1 0 3 3 3 1 Syntaxin T2SF PF00482.18 CCD26669.1 - 0.00026 20.8 0.4 0.00083 19.2 0.3 1.8 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein F Rifin_STEVOR PF02009.11 CCD26669.1 - 0.00043 20.0 5.7 0.00043 20.0 3.9 2.2 1 1 1 2 2 2 1 Rifin/stevor family Synaptobrevin PF00957.16 CCD26669.1 - 0.0043 16.6 2.4 0.0043 16.6 1.7 3.5 2 1 0 3 3 3 1 Synaptobrevin DUF4094 PF13334.1 CCD26669.1 - 0.05 13.9 0.5 0.05 13.9 0.4 3.8 2 1 4 6 6 6 0 Domain of unknown function (DUF4094) DUF3753 PF12575.3 CCD26669.1 - 0.13 12.0 3.6 2.7 7.8 0.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) PTA_PTB PF01515.14 CCD26669.1 - 0.18 10.8 6.4 0.64 9.0 3.0 2.2 1 1 1 2 2 2 0 Phosphate acetyl/butaryl transferase DUF3722 PF12519.3 CCD26669.1 - 0.87 8.7 7.7 1.9 7.6 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3722) DUF2116 PF09889.4 CCD26669.1 - 1.2 8.9 5.7 0.7 9.7 0.6 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF3802 PF12290.3 CCD26670.1 - 0.06 13.6 1.7 0.11 12.8 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3802) EF-hand_7 PF13499.1 CCD26670.1 - 0.083 13.0 0.8 0.16 12.1 0.3 1.6 2 0 0 2 2 2 0 EF-hand domain pair DUF2435 PF10363.4 CCD26671.1 - 4.9e-28 96.8 1.9 1e-27 95.8 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2435) DUF740 PF05340.7 CCD26671.1 - 9.3 4.4 4.7 14 3.8 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) HSP90 PF00183.13 CCD26672.1 - 2.2e-254 844.8 43.4 2.5e-254 844.5 30.1 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 CCD26672.1 - 4.3e-11 42.5 0.0 7.7e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCD26672.1 - 1.6e-10 40.7 0.0 1.6e-10 40.7 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M13 PF01431.16 CCD26672.1 - 2.9 6.9 5.5 1.6 7.8 1.2 2.2 2 0 0 2 2 2 0 Peptidase family M13 RINGv PF12906.2 CCD26673.1 - 4.3e-05 23.4 6.0 9.7e-05 22.3 4.2 1.6 1 0 0 1 1 1 1 RING-variant domain DiS_P_DiS PF06750.8 CCD26673.1 - 0.0019 17.9 0.1 0.0044 16.7 0.0 1.6 1 0 0 1 1 1 1 Bacterial Peptidase A24 N-terminal domain zf-RING_2 PF13639.1 CCD26673.1 - 0.3 10.9 10.1 0.5 10.2 4.2 2.3 2 0 0 2 2 2 0 Ring finger domain FANCL_C PF11793.3 CCD26673.1 - 0.72 9.8 8.5 13 5.8 4.0 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 CCD26673.1 - 0.79 9.3 6.4 30 4.2 0.0 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Ribosomal_S17 PF00366.15 CCD26674.1 - 3.6e-15 55.7 1.0 8.5e-15 54.5 0.7 1.7 1 0 0 1 1 1 1 Ribosomal protein S17 DUF2316 PF10078.4 CCD26674.1 - 2.8 7.9 7.2 0.29 11.1 1.0 2.3 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2316) GDC-P PF02347.11 CCD26675.1 - 3.9e-189 628.7 0.0 9.9e-177 587.9 0.0 2.4 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 CCD26675.1 - 0.0097 15.0 0.0 0.036 13.1 0.0 1.8 2 0 0 2 2 2 1 Beta-eliminating lyase Pkinase PF00069.20 CCD26676.1 - 3.9e-41 140.9 0.0 7.9e-41 139.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26676.1 - 2.1e-14 53.2 0.0 3.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCD26676.1 - 0.0071 16.1 0.4 0.075 12.7 0.0 2.4 3 0 0 3 3 3 1 Phosphotransferase enzyme family Ribosomal_L12 PF00542.14 CCD26677.1 - 2.5e-20 72.2 6.8 2.5e-20 72.2 4.7 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain CSTF2_hinge PF14327.1 CCD26677.1 - 0.058 13.4 1.0 4.5 7.4 0.1 2.4 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 RNA_POL_M_15KD PF02150.11 CCD26678.1 - 1.2e-16 60.0 4.2 1.2e-16 60.0 2.9 2.5 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 CCD26678.1 - 2.2e-13 49.5 15.1 2.4e-13 49.4 1.8 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF2387 PF09526.5 CCD26678.1 - 0.0031 17.4 3.4 0.13 12.2 0.3 2.3 2 0 0 2 2 2 1 Probable metal-binding protein (DUF2387) Lar_restr_allev PF14354.1 CCD26678.1 - 0.0048 17.1 2.7 0.079 13.2 0.2 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar Rubredoxin PF00301.15 CCD26678.1 - 0.0072 16.1 3.7 25 4.8 0.0 4.0 4 0 0 4 4 4 0 Rubredoxin DZR PF12773.2 CCD26678.1 - 0.012 15.3 8.3 0.2 11.4 0.3 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-UBP PF02148.14 CCD26678.1 - 0.014 15.4 4.0 0.23 11.6 0.3 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Zn_Tnp_IS1595 PF12760.2 CCD26678.1 - 0.075 12.8 12.1 5.1 6.9 0.6 3.2 2 1 1 3 3 3 0 Transposase zinc-ribbon domain C1_4 PF07975.7 CCD26678.1 - 0.1 12.6 11.0 0.28 11.1 0.7 2.9 2 1 1 3 3 3 0 TFIIH C1-like domain zf-ribbon_3 PF13248.1 CCD26678.1 - 0.16 11.2 7.6 1.8 7.8 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain zf-CHY PF05495.7 CCD26678.1 - 0.19 11.8 7.2 0.89 9.7 1.3 2.3 2 0 0 2 2 2 0 CHY zinc finger IBR PF01485.16 CCD26678.1 - 0.22 11.4 6.9 1.1 9.1 0.3 2.6 2 1 0 2 2 2 0 IBR domain Cytochrom_c3_2 PF14537.1 CCD26678.1 - 0.27 11.6 4.1 0.26 11.6 0.6 2.1 2 0 0 2 2 2 0 Cytochrome c3 Zn-ribbon_8 PF09723.5 CCD26678.1 - 0.31 11.0 9.1 7.8 6.5 0.3 3.9 4 0 0 4 4 4 0 Zinc ribbon domain GFA PF04828.9 CCD26678.1 - 0.42 10.5 5.7 7.2 6.6 0.8 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme DUF2296 PF10058.4 CCD26678.1 - 0.53 10.0 7.6 0.54 10.0 0.4 2.6 2 1 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Nudix_N_2 PF14803.1 CCD26678.1 - 1.5 8.5 10.7 3.2 7.5 0.6 3.4 3 0 0 3 3 3 0 Nudix N-terminal ArfGap PF01412.13 CCD26678.1 - 1.9 8.3 5.2 1.6 8.4 0.6 2.3 2 1 0 2 2 2 0 Putative GTPase activating protein for Arf Rpr2 PF04032.11 CCD26678.1 - 3.1 7.7 9.4 3.6e+02 1.0 6.5 2.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Cytochrom_NNT PF03264.9 CCD26678.1 - 6.1 6.2 8.6 0.11 11.8 0.7 2.0 2 1 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region HypA PF01155.14 CCD26678.1 - 8.2 6.1 8.1 53 3.5 3.1 2.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family AFT PF08731.6 CCD26679.1 - 3e-44 149.7 0.6 3e-44 149.7 0.4 4.0 4 1 0 4 4 4 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 CCD26679.1 - 0.00057 19.4 1.0 0.098 12.2 0.0 2.6 2 0 0 2 2 2 2 MuDR family transposase HSF_DNA-bind PF00447.12 CCD26680.1 - 6.3e-33 113.0 3.9 6.3e-33 113.0 2.7 3.0 1 1 1 2 2 2 1 HSF-type DNA-binding Fib_alpha PF08702.5 CCD26681.1 - 0.35 10.9 11.6 0.2 11.7 1.7 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ribosomal_L30 PF00327.15 CCD26682.1 - 9.4e-20 69.9 2.1 1.8e-19 69.0 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CCD26682.1 - 1e-17 63.8 16.8 1.7e-17 63.1 11.7 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DUF3035 PF11233.3 CCD26682.1 - 1.2 9.1 5.0 1.6 8.7 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) AA_permease_2 PF13520.1 CCD26683.1 - 6.7e-49 166.5 49.2 8.1e-49 166.2 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCD26683.1 - 6.1e-24 84.2 39.5 7.1e-24 83.9 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease DEAD PF00270.24 CCD26684.1 - 1.3e-50 171.2 0.0 7.3e-49 165.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD26684.1 - 4.5e-29 100.1 0.0 6e-28 96.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 CCD26684.1 - 0.001 17.5 0.0 0.001 17.5 0.0 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF1253) CMS1 PF14617.1 CCD26684.1 - 0.0012 17.9 14.9 0.002 17.2 0.0 2.5 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.1 CCD26684.1 - 0.069 13.2 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain RP-C_C PF11800.3 CCD26684.1 - 2.7 7.6 6.2 4.6 6.8 4.3 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region KxDL PF10241.4 CCD26685.1 - 1.9e-07 30.9 2.0 3.6e-07 29.9 1.4 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein Syntaxin-6_N PF09177.6 CCD26685.1 - 0.034 14.5 1.4 0.034 14.5 1.0 2.8 2 2 0 2 2 2 0 Syntaxin 6, N-terminal GTPase_Cys_C PF12631.2 CCD26685.1 - 0.064 13.6 1.0 1.1 9.7 0.0 2.9 2 1 2 4 4 4 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE GvpK PF05121.7 CCD26685.1 - 0.23 11.2 3.2 0.22 11.3 0.7 2.0 2 0 0 2 2 2 0 Gas vesicle protein K Laminin_II PF06009.7 CCD26685.1 - 0.68 9.6 6.6 2.8 7.7 0.6 2.4 2 0 0 2 2 2 0 Laminin Domain II IncA PF04156.9 CCD26685.1 - 0.81 9.2 8.1 4.7 6.7 1.6 2.1 2 0 0 2 2 2 0 IncA protein MPC PF03650.8 CCD26686.1 - 4e-19 68.7 0.1 4.7e-19 68.4 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF544 PF04424.8 CCD26687.1 - 1.1e-26 92.9 0.1 2.3e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) Pkinase PF00069.20 CCD26688.1 - 5.5e-16 58.5 0.5 9.6e-16 57.7 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26688.1 - 1.1e-07 31.1 0.0 2.1e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SNase PF00565.12 CCD26690.1 - 5e-21 74.9 0.0 1.2e-20 73.8 0.0 1.6 2 0 0 2 2 2 1 Staphylococcal nuclease homologue MAD PF05557.8 CCD26691.1 - 4.3e-31 107.7 74.1 5.6e-31 107.4 51.4 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Fib_alpha PF08702.5 CCD26691.1 - 0.0047 17.0 13.1 0.0047 17.0 9.1 5.4 3 2 3 6 6 6 3 Fibrinogen alpha/beta chain family DUF883 PF05957.8 CCD26691.1 - 1.4 9.3 9.5 11 6.5 0.7 3.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Reo_sigmaC PF04582.7 CCD26691.1 - 2.4 7.2 24.7 0.082 12.0 2.1 4.3 1 1 4 5 5 5 0 Reovirus sigma C capsid protein UQ_con PF00179.21 CCD26692.1 - 4.7e-17 61.7 0.0 5.6e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCD26692.1 - 0.003 17.4 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 RWD domain MF_alpha_N PF05436.6 CCD26693.1 - 1.3e-29 101.6 1.6 1.9e-29 101.1 1.1 1.3 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus MF_alpha PF04648.7 CCD26693.1 - 2.2e-20 71.5 34.9 8.4e-05 22.5 2.0 4.2 4 0 0 4 4 4 4 Yeast mating factor alpha hormone HmuY PF14064.1 CCD26693.1 - 0.2 11.6 4.9 8.1 6.4 0.3 2.8 3 0 0 3 3 3 0 HmuY protein XLF PF09302.6 CCD26694.1 - 1.2e-11 44.6 5.9 3.6e-11 43.1 4.1 1.9 1 1 0 1 1 1 1 XLF (XRCC4-like factor) ParA PF10609.4 CCD26695.1 - 1e-35 121.4 0.1 2e-35 120.5 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCD26695.1 - 2.1e-16 59.8 0.0 3.1e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CCD26695.1 - 6.2e-06 25.4 0.0 9.5e-06 24.8 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 CCD26695.1 - 1.3e-05 25.1 0.0 6.5e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 CCD26695.1 - 0.00083 18.4 1.7 0.0056 15.7 0.1 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase DUF258 PF03193.11 CCD26695.1 - 0.0072 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCD26695.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain TF_Zn_Ribbon PF08271.7 CCD26695.1 - 0.054 12.8 0.3 0.16 11.2 0.2 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding Nup96 PF12110.3 CCD26696.1 - 9.3e-48 162.8 6.1 2.4e-47 161.4 4.2 1.7 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 CCD26696.1 - 9.5e-48 161.5 0.0 9.5e-48 161.5 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CCD26696.1 - 5e-12 46.0 106.3 7.3e-07 29.4 30.5 4.5 2 1 1 3 3 3 2 Nucleoporin FG repeat region Spc7 PF08317.6 CCD26697.1 - 1e-69 234.6 19.9 2.3e-69 233.5 13.8 1.6 1 0 0 1 1 1 1 Spc7 kinetochore protein UCH_1 PF13423.1 CCD26698.1 - 8.9e-42 143.5 5.4 1.3e-41 143.0 3.7 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 CCD26698.1 - 5.2e-24 85.3 0.0 1.3e-23 84.1 0.0 1.7 1 0 0 1 1 1 1 Exonuclease PHD PF00628.24 CCD26699.1 - 1.4e-10 40.6 6.3 2.9e-10 39.6 4.4 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCD26699.1 - 0.47 9.8 6.3 0.8 9.0 4.4 1.4 1 0 0 1 1 1 0 PHD-finger RRM_1 PF00076.17 CCD26700.1 - 3.2e-13 49.0 0.0 7e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD26700.1 - 1.2e-12 47.5 0.0 2e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD26700.1 - 4.1e-09 36.1 0.6 1.3e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Homeobox_KN PF05920.6 CCD26701.1 - 1.4e-18 66.3 0.4 3.3e-18 65.1 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CCD26701.1 - 3.3e-06 26.5 0.2 1.2e-05 24.8 0.1 2.0 1 0 0 1 1 1 1 Homeobox domain RCC1 PF00415.13 CCD26702.1 - 3.8e-55 183.8 2.2 6.7e-08 32.6 0.1 7.9 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCD26702.1 - 4.8e-37 124.7 14.8 2.8e-07 29.9 0.0 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Use1 PF09753.4 CCD26703.1 - 5.8e-09 35.7 2.3 9.8e-09 35.0 1.6 1.4 1 0 0 1 1 1 1 Membrane fusion protein Use1 Focal_AT PF03623.8 CCD26703.1 - 0.025 14.0 2.0 0.04 13.3 0.3 1.9 1 1 1 2 2 2 0 Focal adhesion targeting region Nup54 PF13874.1 CCD26703.1 - 0.47 10.1 10.5 0.36 10.5 4.9 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 SNF2_N PF00176.18 CCD26704.1 - 8e-81 271.1 0.8 1.8e-80 269.9 0.6 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CCD26704.1 - 5.7e-37 126.0 1.9 5.7e-37 126.0 1.3 4.1 6 0 0 6 6 6 1 SLIDE HAND PF09110.6 CCD26704.1 - 6.9e-29 100.5 3.8 6.9e-29 100.5 2.6 5.9 4 1 0 4 4 4 1 HAND Helicase_C PF00271.26 CCD26704.1 - 1.6e-16 59.8 0.0 1.1e-15 57.2 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD26704.1 - 1.9e-05 24.2 0.0 5.6e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase WD40 PF00400.27 CCD26705.1 - 3.1e-35 118.8 22.2 3.8e-09 36.0 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCD26705.1 - 0.059 12.1 4.7 1.9 7.1 0.1 3.2 2 2 1 3 3 3 0 Nup133 N terminal like YmzC PF14157.1 CCD26705.1 - 0.077 12.8 0.0 1.3 8.8 0.0 2.9 4 0 0 4 4 4 0 YmzC-like protein HD_3 PF13023.1 CCD26706.1 - 5.3e-36 123.8 0.1 6.7e-36 123.5 0.1 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 CCD26706.1 - 4.2e-05 23.5 0.0 7.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 HD domain Ribosomal_L18e PF00828.14 CCD26707.1 - 2.4e-33 115.2 0.2 3.3e-33 114.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Sugar_tr PF00083.19 CCD26708.1 - 4.8e-77 259.4 12.7 6.7e-77 258.9 8.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD26708.1 - 1.4e-23 83.1 20.2 7.1e-22 77.5 11.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCD26708.1 - 2.1e-06 26.2 0.4 5.3e-06 24.9 0.3 1.6 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) EF-hand_7 PF13499.1 CCD26709.1 - 3e-15 56.1 1.3 1.8e-10 40.7 0.4 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CCD26709.1 - 6.6e-10 38.4 3.3 1.3e-06 27.9 0.3 3.7 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 CCD26709.1 - 1.2e-09 37.1 5.7 0.0012 18.4 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CCD26709.1 - 1.9e-09 36.1 8.3 0.00052 19.1 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 CCD26709.1 - 7.5e-07 28.9 0.0 0.0017 18.2 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 CCD26709.1 - 0.0008 18.6 8.0 0.61 9.5 0.1 3.5 3 0 0 3 3 3 3 EF hand UPF0154 PF03672.8 CCD26709.1 - 0.01 15.4 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Peptidase_M17_N PF02789.12 CCD26709.1 - 0.094 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain Toxin_R_bind_N PF07953.7 CCD26709.1 - 0.099 12.1 0.9 0.19 11.2 0.6 1.5 1 1 0 1 1 1 0 Clostridium neurotoxin, N-terminal receptor binding FliG_N PF14842.1 CCD26709.1 - 0.1 12.7 0.2 0.18 11.9 0.1 1.4 1 0 0 1 1 1 0 FliG N-terminal domain FDX-ACB PF03147.9 CCD26709.1 - 0.11 12.7 0.1 0.41 10.8 0.1 1.8 1 1 1 2 2 2 0 Ferredoxin-fold anticodon binding domain EF-hand_4 PF12763.2 CCD26709.1 - 0.11 12.1 0.6 0.63 9.8 0.1 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Dicty_REP PF05086.7 CCD26711.1 - 0.35 8.5 9.2 0.35 8.5 6.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 CCD26711.1 - 1.2 8.9 13.2 1.6 8.5 9.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein CUE PF02845.11 CCD26712.1 - 0.0026 17.2 0.1 0.008 15.6 0.0 1.9 1 0 0 1 1 1 1 CUE domain DUF3280 PF11684.3 CCD26712.1 - 0.008 16.3 0.6 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2380) WD40 PF00400.27 CCD26713.1 - 7.3e-20 70.0 10.7 1.6e-06 27.7 0.3 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 CCD26713.1 - 0.0011 18.6 0.3 0.065 12.9 0.1 2.5 2 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Rax2 PF12768.2 CCD26713.1 - 0.0071 15.5 0.2 0.016 14.4 0.2 1.5 1 0 0 1 1 1 1 Cortical protein marker for cell polarity mRNA_cap_C PF03919.10 CCD26713.1 - 0.11 12.8 0.1 0.76 10.1 0.0 2.3 2 0 0 2 2 2 0 mRNA capping enzyme, C-terminal domain DASH_Dad3 PF08656.5 CCD26714.1 - 6.2e-26 89.8 1.2 6.9e-26 89.7 0.8 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 FtsQ PF03799.10 CCD26714.1 - 0.011 15.9 0.1 0.012 15.7 0.0 1.2 1 0 0 1 1 1 0 Cell division protein FtsQ EAP30 PF04157.11 CCD26714.1 - 0.1 11.7 0.1 0.11 11.6 0.1 1.0 1 0 0 1 1 1 0 EAP30/Vps36 family BAR PF03114.13 CCD26714.1 - 0.13 11.7 0.5 5.7 6.3 0.1 1.9 1 1 1 2 2 2 0 BAR domain DUF1546 PF07571.8 CCD26715.1 - 1.2e-29 102.3 0.0 2.3e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 CCD26715.1 - 2.2e-27 94.8 0.3 4.6e-27 93.7 0.2 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 CCD26715.1 - 0.00049 20.1 0.2 0.0012 18.9 0.1 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.9 CCD26715.1 - 0.0043 16.3 0.0 0.0081 15.4 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CENP-S PF15630.1 CCD26715.1 - 0.0075 16.4 0.9 0.48 10.6 0.1 3.2 3 0 0 3 3 3 1 Kinetochore component CENP-S SLD3 PF08639.5 CCD26716.1 - 1e-71 242.1 31.4 2.3e-71 240.9 21.8 1.6 1 1 0 1 1 1 1 DNA replication regulator SLD3 KH_1 PF00013.24 CCD26717.1 - 8.7e-33 111.7 8.6 1.7e-11 43.6 2.4 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCD26717.1 - 1.3e-25 88.5 12.9 4e-10 39.1 2.2 3.6 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CCD26717.1 - 8e-08 31.8 0.1 0.012 15.1 0.0 3.6 3 0 0 3 3 3 2 KH domain KH_2 PF07650.12 CCD26717.1 - 1.2e-07 31.1 6.6 0.056 13.0 0.3 3.8 4 0 0 4 4 4 3 KH domain OPT PF03169.10 CCD26718.1 - 4.8e-155 517.4 19.9 5.5e-155 517.3 13.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein IncA PF04156.9 CCD26718.1 - 6.8 6.2 7.7 20 4.7 5.3 1.8 1 0 0 1 1 1 0 IncA protein CBS PF00571.23 CCD26720.1 - 5.8e-30 102.8 4.3 2.1e-14 52.9 0.1 4.2 4 0 0 4 4 4 4 CBS domain HTH_9 PF08221.6 CCD26720.1 - 0.077 12.8 1.4 1.2 9.0 0.1 3.0 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain WD40 PF00400.27 CCD26721.1 - 3.6e-18 64.6 15.2 1.2e-05 24.9 0.1 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat GvpL_GvpF PF06386.6 CCD26722.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF CENP-O PF09496.5 CCD26724.1 - 3.9e-07 30.2 0.0 9.1e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component DivIC PF04977.10 CCD26724.1 - 0.018 14.4 0.8 0.018 14.4 0.6 1.7 2 0 0 2 2 2 0 Septum formation initiator Filament PF00038.16 CCD26724.1 - 0.055 12.9 0.1 0.088 12.2 0.1 1.3 1 0 0 1 1 1 0 Intermediate filament protein Spc24 PF08286.6 CCD26724.1 - 0.82 9.3 4.3 0.78 9.4 0.5 2.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 ABC1 PF03109.11 CCD26725.1 - 2e-37 127.8 0.1 8.6e-37 125.7 0.0 2.1 2 0 0 2 2 2 1 ABC1 family HA2 PF04408.18 CCD26726.1 - 1e-26 92.9 0.0 2.6e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCD26726.1 - 1.3e-25 89.4 0.0 3.2e-25 88.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCD26726.1 - 2.8e-11 43.1 0.0 6.1e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD26726.1 - 4.2e-09 36.1 0.3 7.2e-09 35.3 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCD26726.1 - 1.7e-06 28.2 0.1 6.4e-06 26.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 CCD26726.1 - 4.3e-05 23.0 0.1 0.0001 21.7 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 CCD26726.1 - 0.00033 20.4 0.1 0.00067 19.4 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain ResIII PF04851.10 CCD26726.1 - 0.0019 18.0 4.1 0.0045 16.8 0.1 2.6 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit AAA_23 PF13476.1 CCD26726.1 - 0.002 18.4 0.1 0.063 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 CCD26726.1 - 0.009 14.9 0.0 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 CCD26726.1 - 0.015 14.8 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CCD26726.1 - 0.036 13.5 0.0 14 5.0 0.0 3.3 3 0 0 3 3 3 0 AAA-like domain PhoH PF02562.11 CCD26726.1 - 0.06 12.5 0.0 0.27 10.4 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein AAA_29 PF13555.1 CCD26726.1 - 0.14 11.6 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Rootletin PF15035.1 CCD26727.1 - 0.012 15.6 0.7 0.017 15.1 0.5 1.2 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Nab2 PF11517.3 CCD26728.1 - 1.9e-44 150.1 3.5 2.9e-44 149.5 2.5 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.1 CCD26728.1 - 2.1e-15 56.0 66.0 0.00019 21.2 4.7 7.6 7 1 0 7 7 7 6 Zinc finger C-x8-C-x5-C-x3-H type DUF935 PF06074.7 CCD26728.1 - 1.2 7.7 3.5 1.2 7.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF935) Ribosomal_S5 PF00333.15 CCD26729.1 - 4.9e-29 99.8 2.8 4.9e-29 99.8 1.9 2.1 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CCD26729.1 - 2.4e-21 74.7 0.1 4.1e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain E3_binding PF02817.12 CCD26729.1 - 0.11 12.1 1.7 0.37 10.4 0.0 2.3 2 0 0 2 2 2 0 e3 binding domain Mon1 PF03164.9 CCD26730.1 - 4.6e-128 427.3 1.2 6e-128 426.9 0.9 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Bacillus_HBL PF05791.6 CCD26730.1 - 0.053 12.8 1.6 0.11 11.8 1.1 1.5 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) FA_desaturase PF00487.19 CCD26731.1 - 1.2e-18 67.5 15.6 1.2e-18 67.5 10.8 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 CCD26731.1 - 7.4e-13 48.1 0.0 1.8e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CBS PF00571.23 CCD26732.1 - 2.9e-24 84.5 1.0 4.6e-06 26.3 0.0 5.4 5 0 0 5 5 5 5 CBS domain GARS_N PF02844.10 CCD26732.1 - 0.1 13.0 0.0 0.3 11.5 0.0 1.8 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain UQ_con PF00179.21 CCD26734.1 - 3.5e-48 162.5 0.1 4.1e-48 162.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCD26734.1 - 0.00011 21.9 0.0 0.00019 21.2 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CCD26734.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 UEV domain Nucleoplasmin PF03066.10 CCD26734.1 - 2.7 7.5 6.9 3.7 7.0 4.8 1.2 1 0 0 1 1 1 0 Nucleoplasmin BCDHK_Adom3 PF10436.4 CCD26735.1 - 2.4e-36 124.7 0.9 4.8e-36 123.7 0.6 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCD26735.1 - 1.4e-07 31.2 0.0 0.0016 18.1 0.0 2.3 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3990 PF13151.1 CCD26736.1 - 0.12 11.7 1.4 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) Kinetochor_Ybp2 PF08568.5 CCD26738.1 - 4.7e-131 438.1 25.8 5.2e-131 437.9 17.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin DASH_Duo1 PF08651.5 CCD26739.1 - 2.7e-28 97.3 0.7 7.5e-28 95.9 0.2 2.0 2 0 0 2 2 2 1 DASH complex subunit Duo1 AbbA_antirepres PF14156.1 CCD26739.1 - 0.052 13.2 1.3 0.15 11.7 0.6 1.9 2 0 0 2 2 2 0 Antirepressor AbbA YqfQ PF14181.1 CCD26739.1 - 0.27 11.2 2.2 1.4 8.9 0.0 2.1 2 0 0 2 2 2 0 YqfQ-like protein CPSase_L_D2 PF02786.12 CCD26740.1 - 5.9e-83 277.3 0.2 1e-82 276.5 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CCD26740.1 - 3.1e-67 225.8 0.0 5e-67 225.1 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CCD26740.1 - 2.2e-35 121.0 0.0 5.2e-35 119.8 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCD26740.1 - 1.1e-30 105.7 0.0 4.4e-30 103.8 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CCD26740.1 - 7e-28 97.8 0.0 1.4e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 HMGL-like ATPgrasp_Ter PF15632.1 CCD26740.1 - 4.2e-19 68.4 0.0 7e-18 64.4 0.0 2.7 3 1 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 CCD26740.1 - 1.5e-18 66.1 2.4 1.5e-18 66.1 1.6 2.1 3 0 0 3 3 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CCD26740.1 - 1.5e-16 60.6 0.2 2.8e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CCD26740.1 - 8.5e-09 34.9 1.9 0.0029 17.2 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp PF02222.17 CCD26740.1 - 2.4e-08 33.5 0.0 4.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCD26740.1 - 2.3e-07 30.4 0.0 4.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CCD26740.1 - 2.2e-05 24.3 0.0 5.4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CCD26740.1 - 0.00012 21.6 0.0 0.00052 19.5 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD PF00529.15 CCD26740.1 - 0.00024 20.5 2.0 0.3 10.3 0.1 2.8 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_3 PF13437.1 CCD26740.1 - 0.00091 19.5 0.2 0.59 10.5 0.0 3.0 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 CCD26740.1 - 0.025 13.7 4.2 0.041 13.0 0.2 2.4 2 1 1 3 3 3 0 HlyD family secretion protein RnfC_N PF13375.1 CCD26740.1 - 0.13 12.0 3.5 0.47 10.2 0.6 3.1 2 1 1 3 3 3 0 RnfC Barrel sandwich hybrid domain Gemini_coat PF00844.13 CCD26741.1 - 0.0092 15.2 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Geminivirus coat protein/nuclear export factor BR1 family Med31 PF05669.7 CCD26743.1 - 9.1e-34 115.2 0.7 1.1e-33 114.9 0.5 1.2 1 0 0 1 1 1 1 SOH1 Scs3p PF10261.4 CCD26744.1 - 2.8e-67 226.2 10.2 4.1e-67 225.6 7.1 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM K-box PF01486.12 CCD26744.1 - 0.0064 16.2 1.0 0.011 15.5 0.7 1.3 1 0 0 1 1 1 1 K-box region PAP2 PF01569.16 CCD26744.1 - 7.6 6.2 17.8 2.9 7.5 9.1 2.5 2 1 0 2 2 2 0 PAP2 superfamily Aldo_ket_red PF00248.16 CCD26745.1 - 4.8e-61 206.0 0.0 5.4e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MTHFR PF02219.12 CCD26746.1 - 1.9e-123 411.1 0.0 2.5e-123 410.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Cornichon PF03311.9 CCD26747.1 - 2.8e-51 172.9 10.1 3.1e-51 172.8 7.0 1.0 1 0 0 1 1 1 1 Cornichon protein Cellulase PF00150.13 CCD26748.1 - 8.6e-16 57.9 0.0 1.6e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) G_glu_transpept PF01019.16 CCD26749.1 - 8.3e-126 420.4 0.0 1.8e-125 419.3 0.0 1.5 1 1 0 1 1 1 1 Gamma-glutamyltranspeptidase zf-U1 PF06220.7 CCD26750.1 - 7.9e-19 66.9 5.5 2.1e-18 65.5 3.8 1.8 1 0 0 1 1 1 1 U1 zinc finger Clr2 PF10383.4 CCD26750.1 - 0.045 13.7 0.1 2.1 8.3 0.0 2.3 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 DUF975 PF06161.6 CCD26751.1 - 0.0059 16.3 2.0 0.0061 16.3 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF975) Ninjurin PF04923.7 CCD26751.1 - 0.018 14.7 0.7 0.023 14.4 0.1 1.6 2 0 0 2 2 2 0 Ninjurin ATP-synt_8 PF00895.15 CCD26751.1 - 0.029 14.5 0.6 0.029 14.5 0.4 2.1 2 0 0 2 2 2 0 ATP synthase protein 8 TMEM154 PF15102.1 CCD26751.1 - 0.044 13.4 1.6 0.049 13.3 1.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF4064 PF13273.1 CCD26751.1 - 0.35 11.0 7.8 0.58 10.2 5.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) OAD_gamma PF04277.8 CCD26751.1 - 2.4 8.6 4.5 5.5 7.4 3.2 1.5 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ExbD PF02472.11 CCD26751.1 - 3.5 7.6 5.6 10 6.0 3.9 1.8 1 1 0 1 1 1 0 Biopolymer transport protein ExbD/TolR TPR_1 PF00515.23 CCD26752.1 - 0.00032 20.1 0.1 0.34 10.6 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCD26752.1 - 0.001 19.3 0.3 0.0074 16.5 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCD26752.1 - 0.0016 18.2 0.0 2.6 8.1 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCD26752.1 - 0.0071 15.9 0.1 4.2 7.0 0.0 2.5 2 1 1 3 3 3 3 TPR repeat NAD_binding_10 PF13460.1 CCD26753.1 - 6.5e-10 39.3 0.0 1.3e-08 35.0 0.0 2.7 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCD26753.1 - 3.4e-08 33.2 0.0 4.6e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 CCD26753.1 - 9.6e-06 25.6 0.0 1.5e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CCD26753.1 - 0.00062 18.7 0.0 0.0009 18.2 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 CCD26753.1 - 0.00097 18.8 0.0 0.0026 17.4 0.0 1.8 3 0 0 3 3 3 1 KR domain 3Beta_HSD PF01073.14 CCD26753.1 - 0.001 17.8 0.0 0.0015 17.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CCD26753.1 - 0.012 14.8 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 CCD26753.1 - 0.016 14.1 0.0 0.026 13.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 CCD26753.1 - 0.049 12.5 0.0 0.081 11.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GTP_EFTU PF00009.22 CCD26754.1 - 8.2e-46 155.8 1.0 8.2e-46 155.8 0.7 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 CCD26754.1 - 6.7e-39 132.1 6.7 1.6e-38 130.9 4.6 1.7 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CCD26754.1 - 1.4e-19 69.7 0.0 4.5e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCD26754.1 - 1.5e-06 28.2 4.1 3e-06 27.2 0.9 2.7 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCD26754.1 - 1.1e-05 25.3 0.0 2.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCD26754.1 - 3.3e-05 24.3 0.1 0.0001 22.8 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CCD26754.1 - 0.00076 18.7 0.1 0.0024 17.1 0.1 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF619 PF04768.8 CCD26754.1 - 0.0027 17.1 0.3 0.0062 15.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF619) EFG_II PF14492.1 CCD26754.1 - 0.013 15.3 0.0 0.037 13.8 0.0 1.8 1 0 0 1 1 1 0 Elongation Factor G, domain II FeoB_N PF02421.13 CCD26754.1 - 0.036 13.3 1.2 0.092 12.0 0.2 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B Hus1 PF04005.7 CCD26755.1 - 3.8e-24 85.1 1.6 4.1e-19 68.6 0.3 2.3 2 0 0 2 2 2 2 Hus1-like protein Ribosomal_S30 PF04758.9 CCD26756.1 - 1.3e-29 101.7 4.5 1.5e-29 101.5 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 GCIP PF13324.1 CCD26757.1 - 3.2e-09 36.4 3.1 1.2e-08 34.5 2.2 1.9 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting YlbD_coat PF14071.1 CCD26757.1 - 2.6 8.1 9.7 2.6 8.1 2.6 2.6 1 1 1 2 2 2 0 Putative coat protein Glyco_hydro_18 PF00704.23 CCD26758.1 - 1.2e-22 80.8 0.7 2.5e-22 79.7 0.5 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.8 CCD26758.1 - 0.006 16.3 2.9 0.006 16.3 2.0 3.3 3 0 0 3 3 3 1 Carbohydrate binding domain (family 19) Methyltransf_16 PF10294.4 CCD26759.1 - 1.9e-12 46.9 0.0 4.4e-12 45.7 0.0 1.6 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CCD26759.1 - 5.7e-05 22.9 0.0 8.1e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD26759.1 - 0.00019 21.9 0.0 0.00035 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCD26759.1 - 0.15 11.6 0.1 0.3 10.6 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Sda PF08970.5 CCD26759.1 - 0.38 10.2 1.8 12 5.4 0.0 2.7 3 0 0 3 3 3 0 Sporulation inhibitor A ECH PF00378.15 CCD26760.1 - 2.1e-15 56.5 0.0 2.8e-09 36.4 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family Syndecan PF01034.15 CCD26760.1 - 0.0004 19.9 0.0 0.00068 19.2 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain DUF2404 PF10296.4 CCD26760.1 - 0.073 13.1 0.3 0.17 12.0 0.2 1.6 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) DsrC PF04358.8 CCD26761.1 - 0.0056 16.9 0.2 0.02 15.1 0.2 1.9 1 0 0 1 1 1 1 DsrC like protein CHD5 PF04420.9 CCD26761.1 - 0.097 12.3 1.5 0.37 10.4 1.1 2.0 1 0 0 1 1 1 0 CHD5-like protein RF-1 PF00472.15 CCD26762.1 - 3e-19 68.8 8.5 2.7e-18 65.8 5.8 2.0 1 1 0 1 1 1 1 RF-1 domain RNase_H2_suC PF08615.6 CCD26762.1 - 0.019 14.8 0.5 0.022 14.6 0.3 1.2 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Borrelia_P83 PF05262.6 CCD26762.1 - 7.6 4.6 13.0 9.2 4.4 9.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Fungal_trans PF04082.13 CCD26763.1 - 4.6e-18 65.0 4.1 9.8e-18 63.9 2.9 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD26763.1 - 1e-07 31.7 7.8 2.6e-07 30.4 5.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CPSF73-100_C PF11718.3 CCD26764.1 - 2e-58 197.3 6.8 2e-58 197.3 4.7 1.7 2 1 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CCD26764.1 - 2.8e-33 114.5 0.0 7.5e-33 113.1 0.0 1.8 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 CCD26764.1 - 8.4e-13 48.3 0.5 1.5e-12 47.5 0.4 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCD26764.1 - 2.4e-11 43.5 2.2 3.1e-10 39.8 0.3 2.4 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 CCD26764.1 - 3e-10 39.7 0.0 6.7e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 CCD26764.1 - 0.00068 19.3 0.1 0.0033 17.1 0.1 2.1 1 1 0 1 1 1 1 Beta-lactamase superfamily domain DUF727 PF05303.7 CCD26764.1 - 0.033 13.9 1.7 0.11 12.2 0.0 2.7 3 1 1 4 4 4 0 Protein of unknown function (DUF727) DEAD PF00270.24 CCD26765.1 - 2e-38 131.5 1.2 3.6e-38 130.7 0.9 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD26765.1 - 2.3e-23 81.8 0.1 1.7e-11 43.8 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CCD26765.1 - 0.00016 21.5 0.1 0.00016 21.5 0.1 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DnaI_N PF07319.6 CCD26765.1 - 0.0027 17.9 4.9 0.46 10.7 0.2 3.6 2 1 0 2 2 2 2 Primosomal protein DnaI N-terminus LSM PF01423.17 CCD26766.1 - 8.5e-18 63.6 1.2 1.1e-17 63.2 0.8 1.1 1 0 0 1 1 1 1 LSM domain MCM PF00493.18 CCD26767.1 - 3.9e-142 472.9 0.3 3.9e-142 472.9 0.2 1.4 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 CCD26767.1 - 2.2e-21 76.5 3.9 2.7e-21 76.3 1.5 2.1 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 CCD26767.1 - 1.8e-06 27.7 0.5 1.5e-05 24.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCD26767.1 - 2.4e-06 26.8 0.1 0.00064 18.9 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCD26767.1 - 0.00059 19.4 0.0 0.0054 16.3 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCD26767.1 - 0.022 14.2 0.0 1.3 8.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain Pam16 PF03656.8 CCD26768.1 - 2.4e-06 27.3 0.1 3.2e-06 26.9 0.1 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 CCD26768.1 - 5.3e-06 26.0 0.2 7.8e-06 25.5 0.2 1.3 1 0 0 1 1 1 1 DnaJ domain DPM3 PF08285.6 CCD26768.1 - 0.14 12.0 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Response_reg PF00072.19 CCD26769.1 - 5.3e-20 71.5 0.0 2.5e-13 50.0 0.0 3.0 3 0 0 3 3 3 2 Response regulator receiver domain Vma12 PF11712.3 CCD26769.1 - 0.041 13.5 0.6 0.18 11.5 0.4 2.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ssl1 PF04056.9 CCD26770.1 - 7.8e-89 296.3 0.0 1.1e-88 295.8 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 CCD26770.1 - 1e-21 76.6 11.4 1e-21 76.6 7.9 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 CCD26770.1 - 6.7e-13 49.1 0.0 9.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CCD26770.1 - 0.0096 15.6 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain CpeS PF09367.5 CCD26770.1 - 0.03 14.2 0.5 0.56 10.0 0.7 2.4 2 0 0 2 2 2 0 CpeS-like protein Mem_trans PF03547.13 CCD26770.1 - 0.054 11.7 0.1 0.051 11.8 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Taeniidae_ag PF05596.6 CCD26770.1 - 0.18 11.6 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Taeniidae antigen DUF572 PF04502.8 CCD26770.1 - 2.2 7.4 16.4 4.1 6.5 11.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-HIT PF04438.11 CCD26770.1 - 2.9 7.6 21.7 0.78 9.4 0.6 3.2 3 0 0 3 3 3 0 HIT zinc finger MFS_1 PF07690.11 CCD26771.1 - 5.5e-36 124.0 22.9 1.1e-35 123.0 16.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CRPA PF05745.6 CCD26771.1 - 0.31 10.8 4.1 6.6 6.5 0.1 2.8 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Aa_trans PF01490.13 CCD26772.1 - 1.4e-81 274.0 28.6 1.7e-81 273.8 19.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mpp10 PF04006.7 CCD26773.1 - 2.1e-130 435.9 74.6 2.6e-130 435.6 51.7 1.0 1 0 0 1 1 1 1 Mpp10 protein Adaptin_N PF01602.15 CCD26776.1 - 1.3e-92 310.8 17.3 1.7e-92 310.4 12.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CCD26776.1 - 3.5e-08 33.6 0.0 0.0083 16.3 0.0 3.4 3 1 0 3 3 3 2 HEAT repeats Arm PF00514.18 CCD26776.1 - 0.0071 16.1 0.2 16 5.4 0.0 4.7 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat ENTH PF01417.15 CCD26776.1 - 0.13 12.1 1.4 3.7 7.4 0.0 3.1 2 1 0 3 3 3 0 ENTH domain Abhydro_lipase PF04083.11 CCD26777.1 - 3.1e-17 61.6 0.0 7.4e-17 60.4 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CCD26777.1 - 0.0015 18.4 0.0 0.002 18.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD26777.1 - 0.06 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold chaperone_DMP PF10448.4 CCD26778.1 - 5.5e-27 94.4 0.2 6.2e-27 94.2 0.1 1.0 1 0 0 1 1 1 1 20S proteasome chaperone Fil_haemagg PF05594.9 CCD26778.1 - 0.11 12.8 0.2 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 Haemagluttinin repeat SBDS PF01172.13 CCD26779.1 - 4.2e-33 113.0 2.4 7e-33 112.2 1.7 1.4 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.5 CCD26779.1 - 1.6e-30 105.3 3.2 1.6e-30 105.3 2.2 1.7 2 0 0 2 2 2 1 SBDS protein C-terminal domain COX16 PF14138.1 CCD26780.1 - 5.4e-32 109.8 0.3 5.4e-32 109.8 0.2 2.0 2 1 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 Sec2p PF06428.6 CCD26780.1 - 0.021 14.6 1.3 0.045 13.6 0.9 1.4 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p YopX PF09643.5 CCD26780.1 - 0.028 14.3 0.5 0.04 13.8 0.3 1.4 1 1 0 1 1 1 0 YopX protein DLIC PF05783.6 CCD26782.1 - 4.8e-07 28.8 0.2 6.8e-07 28.3 0.1 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) SYS1 PF09801.4 CCD26783.1 - 3.1e-47 160.2 11.6 3.6e-47 159.9 8.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network PNP_UDP_1 PF01048.15 CCD26784.1 - 2.1e-33 115.2 0.0 2.6e-33 114.9 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily NPCC PF08058.6 CCD26785.1 - 3e-31 108.1 1.4 5.2e-31 107.4 0.9 1.3 1 0 0 1 1 1 1 Nuclear pore complex component NIF PF03031.13 CCD26786.1 - 8.7e-51 171.7 0.6 1.3e-50 171.1 0.1 1.5 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD_2 PF13419.1 CCD26786.1 - 0.048 13.8 0.2 0.67 10.1 0.0 2.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase WD40 PF00400.27 CCD26787.1 - 2.9e-35 118.8 6.3 2.5e-08 33.4 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 CCD26787.1 - 5e-27 93.7 15.1 1.1e-26 92.6 10.5 1.6 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 CCD26787.1 - 0.00024 20.8 0.9 0.0088 15.8 0.1 3.6 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Zn_clus PF00172.13 CCD26788.1 - 2.5e-06 27.2 10.5 2.5e-06 27.2 7.3 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Longin PF13774.1 CCD26789.1 - 7e-22 76.7 0.4 1.2e-21 76.0 0.3 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CCD26789.1 - 1.7e-15 56.3 0.0 3e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin Phi-29_GP16_7 PF06720.6 CCD26789.1 - 0.0026 17.4 0.4 0.0043 16.7 0.2 1.3 1 0 0 1 1 1 1 Bacteriophage phi-29 early protein GP16.7 DUF1664 PF07889.7 CCD26789.1 - 0.0035 17.1 0.4 0.0059 16.4 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) DcpS PF05652.7 CCD26790.1 - 5.3e-39 133.0 0.1 8.9e-39 132.3 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 CCD26790.1 - 1.3e-33 115.6 0.2 2.8e-33 114.5 0.0 1.7 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CCD26790.1 - 0.035 14.6 0.2 0.29 11.6 0.0 2.4 3 0 0 3 3 3 0 HIT domain DUF4187 PF13821.1 CCD26791.1 - 2.6e-16 58.9 1.2 4.7e-16 58.1 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) Cnd1 PF12717.2 CCD26792.1 - 1.6e-50 171.3 27.9 5.9e-50 169.5 2.4 4.2 5 2 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 CCD26792.1 - 2.9e-45 153.9 1.5 2.9e-45 153.9 1.1 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.17 CCD26792.1 - 6.6e-12 44.4 2.1 0.024 14.7 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.1 CCD26792.1 - 1.3e-11 44.5 0.0 0.00059 20.0 0.0 3.8 2 1 1 3 3 3 3 HEAT repeats HEAT_EZ PF13513.1 CCD26792.1 - 7.3e-07 29.5 0.1 2.8 8.5 0.0 4.9 4 0 0 4 4 4 2 HEAT-like repeat DUF2435 PF10363.4 CCD26792.1 - 0.00056 19.7 1.7 2.3 8.1 0.1 4.3 2 2 1 3 3 3 1 Protein of unknown function (DUF2435) Cohesin_HEAT PF12765.2 CCD26792.1 - 0.14 12.1 1.4 35 4.5 0.1 3.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion TPR_11 PF13414.1 CCD26793.1 - 9.7e-22 76.4 6.8 2.3e-17 62.3 1.6 3.0 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 CCD26793.1 - 1.9e-14 52.3 11.7 0.0002 21.0 0.2 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCD26793.1 - 7.2e-13 47.5 6.3 0.0013 18.2 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCD26793.1 - 1.9e-06 27.6 1.5 0.32 11.3 0.3 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCD26793.1 - 0.00019 21.2 6.8 0.0054 16.6 0.3 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCD26793.1 - 0.0047 17.4 0.1 7.5 7.4 0.0 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCD26793.1 - 0.011 16.3 2.9 0.072 13.7 0.0 3.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCD26793.1 - 0.013 15.2 9.9 0.044 13.5 0.1 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCD26793.1 - 0.022 14.5 5.5 4.7 7.2 0.1 3.9 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCD26793.1 - 0.023 15.0 0.1 0.023 15.0 0.1 3.0 4 1 0 4 4 3 0 Tetratricopeptide repeat IER PF05760.7 CCD26793.1 - 0.041 13.7 2.6 0.074 12.9 1.1 1.8 1 1 0 2 2 2 0 Immediate early response protein (IER) Fis1_TPR_C PF14853.1 CCD26793.1 - 0.077 12.8 2.0 0.27 11.1 0.0 3.1 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Apc3 PF12895.2 CCD26793.1 - 0.15 12.2 6.4 0.098 12.8 1.5 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.2 CCD26793.1 - 0.16 11.8 3.4 3.3 7.5 0.5 3.3 1 1 2 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_10 PF13374.1 CCD26793.1 - 0.31 11.0 1.7 1.8 8.5 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 CCD26793.1 - 0.39 10.6 7.3 0.19 11.5 1.3 3.2 1 1 3 4 4 4 0 MIT (microtubule interacting and transport) domain Fcf1 PF04900.7 CCD26794.1 - 1.3e-29 102.2 1.4 1.3e-29 102.2 1.0 2.1 2 1 0 2 2 2 1 Fcf1 DNA_ligase_A_M PF01068.16 CCD26795.1 - 3.6e-48 163.6 0.1 6e-48 162.9 0.1 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CCD26795.1 - 2.8e-14 53.3 0.0 1.9e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 DNA ligase N terminus BRCT PF00533.21 CCD26795.1 - 1e-07 31.9 0.5 3.9e-06 26.9 0.0 2.9 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.10 CCD26795.1 - 0.00015 22.0 0.0 0.00036 20.8 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 CCD26795.1 - 0.0003 20.5 2.6 0.048 13.3 0.8 3.2 2 1 0 2 2 2 1 mRNA capping enzyme, catalytic domain Acetyltransf_1 PF00583.19 CCD26796.1 - 1.4e-08 34.6 0.0 9.4e-08 31.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCD26796.1 - 0.00019 21.5 0.0 0.00046 20.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCD26796.1 - 0.0013 18.7 0.0 0.004 17.2 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCD26796.1 - 0.063 13.0 0.0 6.8 6.5 0.0 2.3 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_3 PF13302.1 CCD26796.1 - 0.082 13.0 0.0 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCD26796.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Peptidase_S8 PF00082.17 CCD26797.1 - 2.1e-46 158.3 0.8 3.2e-46 157.7 0.5 1.2 1 0 0 1 1 1 1 Subtilase family RRN7 PF11781.3 CCD26798.1 - 3.5e-09 36.0 0.6 6.6e-09 35.1 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 CENP-P PF13096.1 CCD26798.1 - 0.12 11.6 0.1 0.12 11.6 0.0 2.4 3 0 0 3 3 3 0 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P Clat_adaptor_s PF01217.15 CCD26799.1 - 1.1e-54 184.0 1.7 1.4e-54 183.6 1.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF4041 PF13250.1 CCD26799.1 - 0.035 13.6 0.2 0.12 11.9 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) zf-UBR PF02207.15 CCD26800.1 - 3.2e-12 45.9 12.7 8.1e-12 44.6 8.8 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) tRNA-synt_1b PF00579.20 CCD26801.1 - 1.2e-75 254.3 0.0 1.5e-75 254.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HlyIII PF03006.15 CCD26802.1 - 6.8e-69 231.6 20.3 8.8e-69 231.2 14.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related SPRY PF00622.23 CCD26803.1 - 0.035 14.1 0.0 5 7.2 0.0 3.1 2 1 0 2 2 2 0 SPRY domain Fungal_trans PF04082.13 CCD26804.1 - 1.3e-38 132.4 0.4 1.5e-37 128.9 0.3 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD26804.1 - 7.3e-10 38.5 9.7 1.4e-09 37.7 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAGK_cat PF00781.19 CCD26805.1 - 9.2e-26 89.8 0.0 3e-25 88.1 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Ras PF00071.17 CCD26806.1 - 5e-57 191.7 0.5 6.2e-57 191.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD26806.1 - 8e-22 77.9 0.2 2.1e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCD26806.1 - 1.3e-15 57.1 0.6 1.4e-15 56.9 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCD26806.1 - 8.8e-06 25.6 0.0 2.3e-05 24.2 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCD26806.1 - 2.9e-05 23.3 0.0 7.4e-05 22.0 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CCD26806.1 - 4.7e-05 22.8 0.1 0.00021 20.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCD26806.1 - 5.8e-05 22.3 0.2 7.3e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CCD26806.1 - 0.0012 18.2 0.7 0.011 15.2 0.5 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 CCD26806.1 - 0.0024 18.0 0.0 0.017 15.2 0.0 2.1 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCD26806.1 - 0.0097 15.6 0.1 0.021 14.5 0.0 1.6 1 1 1 2 2 2 1 Archaeal ATPase AAA_24 PF13479.1 CCD26806.1 - 0.011 15.3 0.2 0.04 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CCD26806.1 - 0.016 14.3 0.0 0.044 12.9 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCD26806.1 - 0.042 13.8 0.0 0.12 12.3 0.0 1.6 2 1 0 2 2 2 0 AAA ATPase domain NACHT PF05729.7 CCD26806.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 CCD26806.1 - 0.1 12.3 0.0 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Red1 PF07964.6 CCD26807.1 - 1.8e-83 280.9 76.8 4.7e-83 279.6 47.3 2.4 2 0 0 2 2 2 2 Rec10 / Red1 Ribosomal_S28e PF01200.13 CCD26808.1 - 1e-33 114.8 3.3 1.1e-33 114.7 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Musclin PF11037.3 CCD26809.1 - 0.0073 15.9 0.2 0.015 14.9 0.1 1.5 1 0 0 1 1 1 1 Insulin-resistance promoting peptide in skeletal muscle XLF PF09302.6 CCD26809.1 - 0.27 11.0 13.2 0.089 12.5 6.5 2.3 2 1 0 2 2 2 0 XLF (XRCC4-like factor) GATase_2 PF00310.16 CCD26811.1 - 1.5e-24 86.3 0.3 1.4e-18 66.7 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCD26811.1 - 2.2e-13 50.3 0.0 4.9e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CCD26811.1 - 6.2e-11 42.1 0.0 1.2e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 CCD26811.1 - 1.9e-09 37.3 0.1 3.3e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 CCD26811.1 - 1.9e-05 23.5 0.0 3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Adap_comp_sub PF00928.16 CCD26811.1 - 0.067 12.2 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Adaptor complexes medium subunit family ABC_tran PF00005.22 CCD26812.1 - 6.5e-33 113.9 0.0 1.2e-32 113.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 CCD26812.1 - 6.7e-32 110.9 11.1 9.3e-32 110.5 7.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 CCD26812.1 - 5.1e-09 36.5 3.8 0.00048 20.1 0.0 4.3 3 1 1 4 4 4 2 AAA domain SMC_N PF02463.14 CCD26812.1 - 8e-08 31.7 0.2 0.00019 20.7 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCD26812.1 - 2.2e-05 25.2 0.0 6.1e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCD26812.1 - 2.4e-05 24.4 0.0 5.4e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.4 CCD26812.1 - 0.00069 18.3 0.1 0.022 13.3 0.0 2.2 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 CCD26812.1 - 0.00077 18.9 0.1 0.0025 17.3 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 CCD26812.1 - 0.0026 16.9 0.0 0.0059 15.7 0.0 1.6 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 CCD26812.1 - 0.0041 17.2 0.1 0.029 14.5 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CCD26812.1 - 0.014 14.3 0.0 0.027 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 CCD26812.1 - 0.016 14.6 0.1 0.042 13.2 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 CCD26812.1 - 0.018 15.3 0.1 0.24 11.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CCD26812.1 - 0.053 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CCD26812.1 - 0.08 12.8 0.5 0.39 10.6 0.4 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 CCD26812.1 - 0.081 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CCD26812.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CCD26812.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCD26812.1 - 0.16 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Epimerase PF01370.16 CCD26813.1 - 1.8e-17 63.5 0.1 2.4e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCD26813.1 - 3.7e-16 58.6 0.4 4.8e-16 58.2 0.3 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCD26813.1 - 6.3e-12 44.9 0.2 1.5e-11 43.7 0.2 1.5 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CCD26813.1 - 8.1e-09 35.7 0.3 1.2e-08 35.1 0.2 1.3 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CCD26813.1 - 1.5e-06 28.2 0.1 3.7e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCD26813.1 - 7.6e-05 21.7 0.6 0.0008 18.3 0.4 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 CCD26813.1 - 8.6e-05 22.2 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 CCD26813.1 - 0.00013 21.2 0.6 0.0012 18.1 0.2 2.2 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.12 CCD26813.1 - 0.00069 19.9 0.4 0.0029 18.0 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF1792 PF08759.6 CCD26813.1 - 0.068 12.7 0.0 3.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1792) CBM_21 PF03370.8 CCD26814.1 - 9.1e-25 86.8 13.9 9.1e-25 86.8 9.6 2.9 2 0 0 2 2 2 1 Putative phosphatase regulatory subunit Myb_DNA-bind_6 PF13921.1 CCD26814.1 - 0.0014 18.6 0.5 0.006 16.6 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCD26814.1 - 0.012 15.6 0.0 0.045 13.7 0.0 1.9 2 0 0 2 2 2 0 Myb-like DNA-binding domain Lyase_1 PF00206.15 CCD26815.1 - 1.4e-114 382.4 0.1 2e-114 382.0 0.1 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CCD26815.1 - 9.1e-25 86.4 0.0 2.7e-24 84.9 0.0 1.8 2 0 0 2 2 2 1 Fumarase C C-terminus dCMP_cyt_deam_1 PF00383.17 CCD26816.1 - 3.7e-08 32.9 0.0 6.7e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region RVT_1 PF00078.22 CCD26818.1 - 2e-19 69.8 0.1 4.3e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3589 PF12141.3 CCD26819.1 - 1.8e-91 306.8 1.8 4.6e-91 305.5 1.3 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) RNA12 PF10443.4 CCD26820.1 - 2.2e-166 553.6 0.6 7.7e-166 551.8 0.1 2.1 2 1 1 3 3 3 1 RNA12 protein RRM_1 PF00076.17 CCD26820.1 - 3e-07 29.9 0.0 6.9e-07 28.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.1 CCD26820.1 - 5.3e-05 23.1 0.3 0.0035 17.2 0.0 3.0 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 CCD26820.1 - 9.5e-05 22.2 0.4 0.0008 19.1 0.0 2.6 1 1 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 CCD26820.1 - 0.02 15.0 0.1 3.5 7.7 0.0 3.3 2 1 0 2 2 2 0 AAA domain UCH PF00443.24 CCD26821.1 - 7e-52 176.1 3.2 1.3e-51 175.2 2.2 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 CCD26821.1 - 2.1e-46 158.0 5.6 2.1e-46 158.0 3.9 3.4 4 0 0 4 4 4 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 CCD26821.1 - 4.7e-34 118.1 0.1 8.2e-34 117.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 CCD26821.1 - 1.4e-30 106.4 0.6 1.2e-29 103.3 0.0 2.6 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 MATH PF00917.21 CCD26821.1 - 1.7e-10 41.1 0.1 1.7e-09 37.9 0.0 2.8 2 0 0 2 2 2 1 MATH domain UN_NPL4 PF11543.3 CCD26821.1 - 0.0026 18.0 0.4 0.68 10.2 0.1 3.2 2 0 0 2 2 2 1 Nuclear pore localisation protein NPL4 Glyco_hydro_17 PF00332.13 CCD26822.1 - 6.1e-09 35.3 0.6 6.1e-09 35.3 0.4 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 17 DUF515 PF04415.7 CCD26822.1 - 0.22 9.7 10.8 0.36 9.0 7.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) RAP1 PF07218.6 CCD26822.1 - 0.32 9.0 8.4 0.42 8.6 5.8 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Mucin PF01456.12 CCD26822.1 - 0.46 10.2 26.5 1.2 8.8 18.4 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 CCD26822.1 - 2.6 5.6 4.9 3.2 5.3 3.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Glucan_synthase PF02364.10 CCD26823.1 - 0 1284.6 10.0 0 1284.6 6.9 2.2 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCD26823.1 - 2.2e-37 127.5 0.6 5.6e-37 126.2 0.4 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_72 PF03198.9 CCD26824.1 - 2.3e-144 480.1 9.4 2.3e-144 480.1 6.5 1.3 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.8 CCD26824.1 - 1.1e-27 96.3 4.8 3.6e-27 94.6 3.3 2.0 1 0 0 1 1 1 1 X8 domain HEAT PF02985.17 CCD26825.1 - 2.2e-22 77.0 11.4 0.0037 17.2 0.0 9.9 10 0 0 10 10 9 5 HEAT repeat HEAT_2 PF13646.1 CCD26825.1 - 1.4e-19 70.1 1.5 4.9e-09 36.3 0.0 6.1 4 2 2 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 CCD26825.1 - 3.3e-19 68.7 14.2 3.5e-07 30.5 0.0 10.1 9 1 1 10 10 10 4 HEAT-like repeat MMS19_C PF12460.3 CCD26825.1 - 4.6e-09 35.4 7.8 0.0019 16.9 0.0 4.2 2 1 1 3 3 3 3 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 CCD26825.1 - 3.5e-07 29.8 1.1 0.0049 16.2 0.7 5.0 6 0 0 6 6 6 2 CLASP N terminal Cnd1 PF12717.2 CCD26825.1 - 9.6e-07 28.8 0.6 2.8 7.7 0.0 5.3 3 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CCD26825.1 - 1.5e-06 28.4 0.5 0.0089 16.3 0.0 5.0 4 2 2 6 6 5 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 CCD26825.1 - 2.8e-05 23.7 5.4 2.9 7.8 0.1 6.0 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat ParcG PF10274.4 CCD26825.1 - 6.1e-05 23.0 0.8 0.046 13.6 0.0 3.6 3 0 0 3 3 3 1 Parkin co-regulated protein DUF3385 PF11865.3 CCD26825.1 - 0.004 17.0 0.7 0.13 12.1 0.1 3.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) DNA_alkylation PF08713.6 CCD26825.1 - 0.024 14.1 0.0 0.28 10.6 0.0 2.9 4 0 0 4 4 4 0 DNA alkylation repair enzyme eIF-3c_N PF05470.7 CCD26826.1 - 9.4e-163 542.4 18.4 1.5e-125 419.5 4.5 2.2 1 1 0 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CCD26826.1 - 5.7e-10 39.4 2.5 1.7e-09 37.9 0.2 3.1 3 1 0 3 3 3 1 PCI domain Methyltrn_RNA_3 PF02598.12 CCD26827.1 - 1.7e-92 309.9 0.3 2.5e-92 309.3 0.2 1.2 1 0 0 1 1 1 1 Putative RNA methyltransferase IPP-2 PF04979.9 CCD26828.1 - 0.0012 19.0 26.4 0.033 14.4 0.4 3.1 1 1 1 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) SURF4 PF02077.10 CCD26829.1 - 1.8e-95 319.3 15.0 2.2e-95 319.0 10.4 1.0 1 0 0 1 1 1 1 SURF4 family DUF4395 PF14340.1 CCD26829.1 - 0.16 12.0 9.8 0.045 13.8 3.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4395) DUF4233 PF14017.1 CCD26829.1 - 3.5 7.5 14.2 3.1 7.7 3.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) DUF3336 PF11815.3 CCD26831.1 - 8.8e-26 90.1 0.0 2.2e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CCD26831.1 - 4.4e-09 36.5 0.0 8.9e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase DUF4652 PF15525.1 CCD26831.1 - 0.052 12.9 0.1 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) Proteasome PF00227.21 CCD26832.1 - 1.4e-46 158.1 0.0 1.7e-46 157.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCD26832.1 - 1.1e-12 47.0 0.2 1.9e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.11 CCD26832.1 - 0.024 14.3 0.1 3.3 7.4 0.0 2.3 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK MFS_1 PF07690.11 CCD26833.1 - 1.5e-07 30.5 46.6 6.6e-06 25.0 30.9 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 CCD26833.1 - 1.7e-06 26.5 26.9 3.8e-06 25.3 18.3 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 CCD26833.1 - 0.00014 20.5 8.7 0.00014 20.5 6.1 3.1 3 1 0 3 3 3 1 Sugar (and other) transporter zf-LITAF-like PF10601.4 CCD26833.1 - 3.4 7.5 16.6 5.6 6.8 0.3 4.7 4 0 0 4 4 4 0 LITAF-like zinc ribbon domain AA_permease PF00324.16 CCD26834.1 - 1.2e-117 393.2 41.7 1.5e-117 392.9 28.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD26834.1 - 1.7e-32 112.4 44.2 2.3e-32 112.0 30.7 1.2 1 0 0 1 1 1 1 Amino acid permease UPF0261 PF06792.6 CCD26834.1 - 0.17 10.3 0.0 0.24 9.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0261) PAP_assoc PF03828.14 CCD26834.1 - 1.9 8.4 5.4 0.38 10.7 0.5 2.2 2 0 0 2 2 2 0 Cid1 family poly A polymerase RVT_2 PF07727.9 CCD26835.1 - 2.4e-79 265.7 0.0 4.2e-79 264.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCD26835.1 - 4.1e-22 78.5 0.2 1.3e-21 76.9 0.1 2.0 2 0 0 2 2 1 1 Integrase core domain gag_pre-integrs PF13976.1 CCD26835.1 - 3.6e-11 42.5 0.0 3.6e-11 42.5 0.0 2.6 3 0 0 3 3 2 1 GAG-pre-integrase domain FlxA PF14282.1 CCD26835.1 - 0.01 15.7 7.5 0.035 14.0 5.2 1.9 1 0 0 1 1 1 0 FlxA-like protein ATG16 PF08614.6 CCD26835.1 - 0.012 15.4 0.7 0.025 14.4 0.5 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) IncA PF04156.9 CCD26835.1 - 0.014 15.0 0.6 0.027 14.0 0.4 1.4 1 0 0 1 1 1 0 IncA protein TBPIP PF07106.8 CCD26835.1 - 0.042 13.3 2.2 0.091 12.3 1.5 1.5 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF342 PF03961.8 CCD26835.1 - 0.075 11.4 0.2 0.17 10.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Syntaxin PF00804.20 CCD26835.1 - 0.1 12.8 3.3 0.32 11.1 2.3 1.9 1 0 0 1 1 1 0 Syntaxin FliJ PF02050.11 CCD26835.1 - 0.19 11.7 1.0 0.4 10.7 0.7 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein DUF4200 PF13863.1 CCD26835.1 - 0.27 11.1 2.3 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) TMF_DNA_bd PF12329.3 CCD26835.1 - 3.1 7.6 4.1 30 4.5 0.1 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding NPV_P10 PF05531.7 CCD26835.1 - 6.1 7.1 7.9 0.97 9.7 1.7 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Methyltransf_11 PF08241.7 CCD26836.1 - 6.2e-16 58.6 0.0 9.8e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCD26836.1 - 5.8e-12 45.9 0.0 1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCD26836.1 - 6.9e-11 42.1 0.0 1e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD26836.1 - 7.4e-10 39.4 0.0 1.4e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCD26836.1 - 2.5e-09 36.9 0.0 4.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCD26836.1 - 1.8e-08 34.6 0.0 3.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCD26836.1 - 2e-07 30.3 0.0 3.1e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 CCD26836.1 - 0.0046 16.5 0.0 0.0074 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 CCD26836.1 - 0.0067 15.5 0.0 0.016 14.3 0.0 1.6 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 CCD26836.1 - 0.019 15.0 0.0 0.064 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 CCD26836.1 - 0.043 12.5 0.0 0.072 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.9 CCD26836.1 - 0.061 12.6 0.0 0.097 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PI-PLC-X PF00388.14 CCD26837.1 - 4.2e-51 172.1 0.1 3.2e-50 169.3 0.0 2.6 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CCD26837.1 - 1.3e-37 128.3 0.2 1.3e-37 128.3 0.1 2.4 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 CCD26837.1 - 5.1e-05 23.2 1.5 5.1e-05 23.2 1.1 2.5 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_7 PF13499.1 CCD26837.1 - 0.0024 17.9 2.6 0.0082 16.2 0.2 2.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CCD26837.1 - 0.0037 16.4 0.1 0.6 9.5 0.0 3.4 2 0 0 2 2 2 1 EF hand C2 PF00168.25 CCD26837.1 - 0.022 14.5 0.1 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 C2 domain Peptidase_U35_2 PF14550.1 CCD26837.1 - 0.38 10.3 5.8 0.98 9.0 1.0 3.3 3 1 0 3 3 3 0 Putative phage protease XkdF RrnaAD PF00398.15 CCD26839.1 - 2.7e-66 223.3 0.0 3.1e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CCD26839.1 - 6.6e-10 39.0 0.0 1.1e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD26839.1 - 2e-05 25.1 0.0 3.7e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CCD26839.1 - 0.00034 20.2 0.0 0.0006 19.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 CCD26839.1 - 0.0011 18.1 0.0 0.0036 16.4 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 CCD26839.1 - 0.0011 18.4 0.0 0.0018 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.11 CCD26839.1 - 0.0034 17.0 0.0 0.0068 16.0 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 CCD26839.1 - 0.0034 17.1 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CCD26839.1 - 0.012 14.7 0.1 0.07 12.3 0.0 2.1 3 0 0 3 3 3 0 O-methyltransferase Methyltransf_31 PF13847.1 CCD26839.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CCD26839.1 - 0.031 14.7 0.0 0.067 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PRMT5 PF05185.11 CCD26839.1 - 0.043 12.7 0.1 0.64 8.8 0.0 2.0 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase UPF0158 PF03682.8 CCD26839.1 - 0.051 13.1 0.2 0.11 12.0 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) Methyltransf_4 PF02390.12 CCD26839.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 CCD26839.1 - 0.11 11.6 0.0 0.37 9.8 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family KAR9 PF08580.5 CCD26840.1 - 2.9e-90 303.4 42.0 2.3e-89 300.4 29.1 1.9 1 1 0 1 1 1 1 Yeast cortical protein KAR9 NAAA-beta PF15508.1 CCD26840.1 - 0.0037 17.5 1.1 0.52 10.6 0.1 3.2 3 0 0 3 3 3 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Arch_ATPase PF01637.13 CCD26840.1 - 0.014 15.0 3.9 0.037 13.7 2.7 1.7 1 0 0 1 1 1 0 Archaeal ATPase DUF904 PF06005.7 CCD26840.1 - 0.65 10.3 9.4 34 4.8 6.5 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF904) ABC_membrane PF00664.18 CCD26841.1 - 5.2e-47 160.5 5.6 5.2e-47 160.5 3.9 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 CCD26841.1 - 1.7e-34 119.0 0.4 8e-34 116.8 0.0 2.4 3 0 0 3 3 3 1 ABC transporter SMC_N PF02463.14 CCD26841.1 - 0.00021 20.5 0.0 0.021 14.0 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.12 CCD26841.1 - 0.0012 18.2 0.1 0.12 11.7 0.0 3.0 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_29 PF13555.1 CCD26841.1 - 0.0051 16.3 0.0 0.017 14.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CCD26841.1 - 0.0076 16.2 0.0 0.024 14.6 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CCD26841.1 - 0.018 14.7 0.0 0.057 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CCD26841.1 - 0.02 14.3 0.0 0.07 12.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCD26841.1 - 0.023 14.8 0.1 0.2 11.7 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 CCD26841.1 - 0.031 14.4 0.0 0.28 11.3 0.0 2.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CCD26841.1 - 0.039 13.1 0.0 0.083 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCD26841.1 - 0.087 13.6 0.0 0.18 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP-synt_Eps PF04627.8 CCD26842.1 - 4.6e-19 67.7 0.8 5.5e-19 67.4 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Kelch_3 PF13415.1 CCD26843.1 - 4.1e-33 112.7 7.7 9.7e-08 31.9 0.0 7.4 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CCD26843.1 - 3.6e-28 97.0 14.9 2e-06 27.4 0.0 7.4 5 3 1 6 6 6 6 Galactose oxidase, central domain DUF4110 PF13422.1 CCD26843.1 - 4.2e-26 90.6 0.1 4.2e-26 90.6 0.0 4.7 3 1 1 4 4 4 2 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 CCD26843.1 - 7e-22 76.6 14.1 1.5e-07 31.2 0.2 5.9 4 2 2 6 6 6 5 Kelch motif Kelch_1 PF01344.20 CCD26843.1 - 1.1e-14 53.7 23.8 3.2e-05 23.3 0.4 6.6 7 0 0 7 7 7 5 Kelch motif Kelch_5 PF13854.1 CCD26843.1 - 4.2e-14 52.1 7.2 1.9e-05 24.4 0.1 6.2 6 1 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 CCD26843.1 - 6e-12 44.8 13.8 0.043 13.5 0.3 6.4 6 0 0 6 6 6 4 Kelch motif BUD22 PF09073.5 CCD26843.1 - 2.6 7.0 47.5 0.014 14.4 7.8 3.2 3 0 0 3 3 3 0 BUD22 Nop25 PF09805.4 CCD26843.1 - 3 7.9 45.3 0.13 12.3 6.6 3.3 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) GCR1_C PF12550.3 CCD26844.1 - 3.4e-16 58.8 1.1 9.3e-16 57.4 0.7 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes CDC45 PF02724.9 CCD26844.1 - 0.00087 17.4 10.3 0.00087 17.4 7.1 2.3 2 0 0 2 2 2 1 CDC45-like protein TSC22 PF01166.13 CCD26844.1 - 0.025 14.5 0.5 0.91 9.5 0.2 3.3 2 0 0 2 2 2 0 TSC-22/dip/bun family Vfa1 PF08432.5 CCD26844.1 - 2.1 8.3 26.6 5.4 6.9 6.7 2.9 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 MFS_1 PF07690.11 CCD26845.1 - 1.2e-31 109.7 32.6 1.2e-31 109.7 22.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Myc_N PF01056.13 CCD26845.1 - 4.6 6.3 9.0 2.5 7.1 4.8 1.3 1 1 0 1 1 1 0 Myc amino-terminal region rve PF00665.21 CCD26846.1 - 4e-11 43.0 0.0 6.3e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain SKN1 PF03935.10 CCD26847.1 - 5e-255 846.3 4.9 6.6e-255 845.9 3.4 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) DUF946 PF06101.6 CCD26849.1 - 4.2e-06 25.0 0.8 5.7e-06 24.6 0.5 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) MCM PF00493.18 CCD26850.1 - 2.2e-138 460.6 0.6 3.2e-138 460.0 0.4 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCD26850.1 - 5.3e-21 75.3 2.3 2.1e-20 73.4 0.0 2.9 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCD26850.1 - 2.2e-07 30.2 0.0 1e-06 28.0 0.0 2.0 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCD26850.1 - 0.0043 16.5 0.0 0.0084 15.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 CCD26850.1 - 0.0063 16.2 0.0 0.035 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCD26850.1 - 0.014 14.9 0.0 0.039 13.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RRN3 PF05327.6 CCD26850.1 - 0.16 10.0 7.0 0.27 9.2 4.9 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Aminotran_1_2 PF00155.16 CCD26851.1 - 5e-23 81.6 0.0 6.7e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCD26851.1 - 2.9e-05 23.3 0.0 4.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CCD26851.1 - 0.012 14.7 0.3 0.055 12.5 0.0 2.0 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Pox_L5 PF04872.8 CCD26851.1 - 0.099 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Poxvirus L5 protein family Peptidase_S10 PF00450.17 CCD26853.1 - 9.1e-92 308.3 15.5 3.3e-91 306.5 10.8 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase SPX PF03105.14 CCD26853.1 - 0.0011 18.7 2.7 0.0011 18.7 1.9 3.1 3 1 0 3 3 2 1 SPX domain Spore_YhcN_YlaJ PF09580.5 CCD26853.1 - 0.0015 18.6 2.5 0.0015 18.6 1.7 2.7 3 0 0 3 3 3 1 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Adaptin_binding PF10199.4 CCD26853.1 - 0.0092 16.2 6.8 0.0092 16.2 4.7 3.5 3 0 0 3 3 3 2 Alpha and gamma adaptin binding protein p34 Gti1_Pac2 PF09729.4 CCD26853.1 - 0.017 14.9 5.5 0.55 10.0 0.3 2.5 2 0 0 2 2 2 0 Gti1/Pac2 family KNOX1 PF03790.8 CCD26853.1 - 0.024 13.9 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 KNOX1 domain Ctr PF04145.10 CCD26853.1 - 0.11 12.5 4.5 0.93 9.5 1.2 2.6 2 0 0 2 2 2 0 Ctr copper transporter family Raftlin PF15250.1 CCD26853.1 - 0.14 10.6 9.3 1.5 7.2 0.5 2.3 2 0 0 2 2 2 0 Raftlin GEMIN8 PF15348.1 CCD26853.1 - 0.23 11.4 23.4 0.9 9.5 6.5 2.6 2 0 0 2 2 2 0 Gemini of Cajal bodies-associated protein 8 LMBR1 PF04791.11 CCD26853.1 - 0.5 8.8 3.9 2.2 6.7 0.1 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein FAM60A PF15396.1 CCD26853.1 - 2.6 7.7 11.6 3.4 7.3 0.8 2.5 2 0 0 2 2 2 0 Protein Family FAM60A Kei1 PF08552.6 CCD26853.1 - 2.9 7.5 6.7 19 4.8 0.3 2.6 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Spore_coat_CotO PF14153.1 CCD26853.1 - 3.1 7.2 21.2 0.87 9.0 2.8 2.4 2 0 0 2 2 2 0 Spore coat protein CotO DUF2370 PF10176.4 CCD26853.1 - 4.2 6.6 11.2 1.6 8.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Retrotrans_gag PF03732.12 CCD26854.1 - 0.0023 17.9 0.0 0.0042 17.1 0.0 1.5 1 0 0 1 1 1 1 Retrotransposon gag protein CDP-OH_P_transf PF01066.16 CCD26855.1 - 4.7e-11 42.8 2.8 4.7e-11 42.8 2.0 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NST1 PF13945.1 CCD26855.1 - 0.47 10.4 7.7 0.7 9.9 5.3 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator ACOX PF01756.14 CCD26856.1 - 2.7e-48 163.8 0.1 5.3e-48 162.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 CCD26856.1 - 1.2e-14 53.5 0.3 2.4e-14 52.5 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 CCD26856.1 - 2.6e-12 47.1 0.1 8.5e-12 45.4 0.1 1.9 1 1 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 CCD26856.1 - 0.015 15.3 0.0 0.038 14.0 0.0 1.7 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain AMPKBI PF04739.10 CCD26857.1 - 1e-29 102.3 0.0 1e-29 102.3 0.0 2.5 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain zf-H2C2_2 PF13465.1 CCD26858.1 - 1.7e-09 37.5 19.7 2.9e-06 27.2 4.3 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CCD26858.1 - 9.9e-06 25.6 25.6 3.5e-05 23.8 2.9 3.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD26858.1 - 5.4e-05 23.2 20.2 0.00016 21.8 1.6 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCD26858.1 - 0.0016 18.5 6.1 0.076 13.1 0.7 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding Ras PF00071.17 CCD26859.1 - 2.1e-60 202.7 0.4 2.5e-60 202.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCD26859.1 - 1.2e-19 70.9 0.1 1.9e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCD26859.1 - 2.2e-13 49.8 0.0 2.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCD26859.1 - 1.6e-07 31.2 0.1 2.5e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCD26859.1 - 3.3e-05 23.4 0.1 0.0001 21.7 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_15 PF13175.1 CCD26859.1 - 4.2e-05 22.7 0.4 6e-05 22.2 0.3 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 CCD26859.1 - 0.00074 18.7 0.3 0.0019 17.3 0.1 1.7 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 CCD26859.1 - 0.00097 18.3 0.0 0.0013 17.9 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CCD26859.1 - 0.0073 15.8 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 CCD26859.1 - 0.009 16.0 0.4 0.066 13.2 0.3 2.2 1 1 0 1 1 1 1 AAA ATPase domain KAP_NTPase PF07693.9 CCD26859.1 - 0.009 15.0 0.0 0.012 14.5 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.1 CCD26859.1 - 0.0091 16.1 0.2 0.021 14.9 0.1 1.8 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 CCD26859.1 - 0.0095 15.1 0.0 0.016 14.3 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 CCD26859.1 - 0.02 14.1 0.0 0.038 13.2 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B TraG_N PF07916.6 CCD26859.1 - 0.026 12.9 0.1 0.033 12.6 0.1 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region MgpC PF05220.7 CCD26859.1 - 0.027 13.6 0.9 0.42 9.6 0.1 2.1 1 1 0 2 2 2 0 MgpC protein precursor ABC_tran PF00005.22 CCD26859.1 - 0.03 14.6 0.5 0.048 13.9 0.2 1.5 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 CCD26859.1 - 0.037 13.0 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Septin DUF1128 PF06569.6 CCD26859.1 - 0.037 13.7 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) SpoIIID PF12116.3 CCD26859.1 - 0.084 12.8 0.0 3 7.8 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D ATP_bind_3 PF01171.15 CCD26860.1 - 3.7e-20 72.1 0.0 6.3e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 CCD26860.1 - 7.4e-05 23.0 0.1 0.00025 21.3 0.0 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 CCD26860.1 - 0.0018 16.9 0.0 0.0031 16.1 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.14 CCD26860.1 - 0.027 14.2 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF2616 PF11077.3 CCD26860.1 - 0.067 12.6 3.2 0.19 11.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) Asn_synthase PF00733.16 CCD26860.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase MU117 PF15474.1 CCD26860.1 - 0.14 12.6 3.2 0.15 12.5 0.9 2.0 2 0 0 2 2 2 0 Meiotically up-regulated gene family SNARE PF05739.14 CCD26861.1 - 1.6e-13 50.0 4.6 1.6e-13 50.0 3.2 2.2 2 0 0 2 2 2 1 SNARE domain PX PF00787.19 CCD26861.1 - 2.1e-09 37.1 0.7 5.4e-09 35.8 0.5 1.8 1 0 0 1 1 1 1 PX domain Med9 PF07544.8 CCD26861.1 - 0.066 12.9 5.7 2 8.2 0.0 3.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 NPV_P10 PF05531.7 CCD26861.1 - 6.9 6.9 8.4 2.4 8.4 1.6 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein WD40 PF00400.27 CCD26862.1 - 4.5e-16 58.0 17.0 4.8e-07 29.4 0.6 6.0 6 1 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCD26862.1 - 0.056 13.2 0.0 0.36 10.6 0.0 2.3 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Cyclin_N PF00134.18 CCD26863.1 - 0.00061 19.3 0.3 0.0023 17.4 0.1 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCD26863.1 - 0.0025 18.2 5.8 0.0025 18.2 4.0 2.8 2 1 0 2 2 2 1 Cyclin PAT1 PF09770.4 CCD26863.1 - 7.3 4.6 45.8 1.6 6.8 29.4 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Kinesin PF00225.18 CCD26864.1 - 5.4e-112 373.8 6.6 5.4e-112 373.8 4.5 2.5 3 1 0 3 3 3 1 Kinesin motor domain Nexin_C PF08628.7 CCD26865.1 - 0.2 11.7 5.7 0.054 13.5 1.0 2.1 2 0 0 2 2 2 0 Sorting nexin C terminal BolA PF01722.13 CCD26866.1 - 9.4e-20 70.3 0.0 1.1e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Tox-ART-HYE1 PF15634.1 CCD26866.1 - 0.013 14.4 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 HYE1 signature containing ADP-ribosyltransferase Fucose_iso_N1 PF07881.7 CCD26866.1 - 0.025 14.1 0.1 0.031 13.8 0.0 1.1 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain FAD_binding_3 PF01494.14 CCD26867.1 - 1.1e-16 60.8 2.4 4.5e-10 39.1 0.0 3.1 2 1 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 CCD26867.1 - 0.0011 17.9 0.0 0.011 14.6 0.0 2.3 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.5 CCD26867.1 - 0.0011 17.7 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 CCD26867.1 - 0.03 13.2 0.0 0.059 12.2 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCD26867.1 - 0.033 14.0 0.0 0.077 12.8 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCD26867.1 - 0.073 11.9 0.3 0.11 11.2 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 CCD26867.1 - 0.13 12.3 0.1 0.3 11.1 0.1 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 CCD26867.1 - 0.14 12.1 0.0 0.39 10.7 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NIF3 PF01784.13 CCD26868.1 - 3.8e-64 216.5 0.2 4.6e-64 216.2 0.1 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) YcfA PF07927.7 CCD26868.1 - 0.075 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 YcfA-like protein CTK3 PF12243.3 CCD26868.1 - 0.1 12.2 0.1 0.37 10.4 0.0 1.9 2 0 0 2 2 2 0 CTD kinase subunit gamma CTK3 ABC_tran PF00005.22 CCD26870.1 - 7.7e-50 168.7 1.0 7.8e-25 87.7 0.0 2.9 4 0 0 4 4 2 2 ABC transporter AAA_21 PF13304.1 CCD26870.1 - 1.6e-22 80.8 2.6 1.7e-06 28.2 0.0 4.3 2 2 2 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 CCD26870.1 - 4.3e-20 71.3 4.9 4.3e-20 71.3 3.4 3.3 3 0 0 3 3 2 1 ABC transporter AAA_29 PF13555.1 CCD26870.1 - 5.2e-09 35.5 0.0 0.00062 19.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 CCD26870.1 - 1.8e-08 33.8 6.0 0.33 10.1 0.0 4.7 4 1 1 5 5 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCD26870.1 - 2.1e-08 35.0 0.0 0.002 18.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 CCD26870.1 - 3.5e-08 33.9 0.0 0.0031 18.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 CCD26870.1 - 3.8e-08 33.5 0.0 0.0046 17.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCD26870.1 - 1.6e-07 31.6 0.0 0.0051 17.1 0.0 3.3 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 CCD26870.1 - 4.5e-07 29.1 0.0 0.00043 19.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CCD26870.1 - 5.8e-06 26.2 0.2 0.041 13.8 0.1 3.5 3 2 0 3 3 3 2 50S ribosome-binding GTPase RNA_helicase PF00910.17 CCD26870.1 - 1.4e-05 25.1 0.0 0.15 12.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 CCD26870.1 - 1.5e-05 24.6 0.7 0.19 11.3 0.0 2.8 3 0 0 3 3 2 2 NACHT domain AAA_23 PF13476.1 CCD26870.1 - 2.4e-05 24.7 14.6 0.012 15.9 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_15 PF13175.1 CCD26870.1 - 3.6e-05 22.9 1.2 0.69 8.8 0.0 4.1 3 2 1 4 4 4 2 AAA ATPase domain AAA PF00004.24 CCD26870.1 - 5.1e-05 23.4 0.1 0.24 11.5 0.0 3.2 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CCD26870.1 - 5.3e-05 23.2 0.0 0.29 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CCD26870.1 - 9.4e-05 22.3 0.0 0.53 10.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CCD26870.1 - 0.0001 21.8 0.1 0.49 9.7 0.0 3.3 3 1 0 3 3 3 1 AAA-like domain AAA_16 PF13191.1 CCD26870.1 - 0.00016 21.6 0.6 0.79 9.6 0.0 3.2 3 1 0 3 3 3 2 AAA ATPase domain MobB PF03205.9 CCD26870.1 - 0.00034 20.3 0.1 0.0095 15.6 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B VirE PF05272.6 CCD26870.1 - 0.00036 20.0 0.1 0.3 10.5 0.0 2.7 3 0 0 3 3 3 1 Virulence-associated protein E AAA_33 PF13671.1 CCD26870.1 - 0.00039 20.3 0.8 0.57 10.0 0.0 3.1 4 0 0 4 4 2 1 AAA domain AAA_25 PF13481.1 CCD26870.1 - 0.00078 18.9 0.0 1.3 8.3 0.0 3.2 3 0 0 3 3 3 1 AAA domain MCM PF00493.18 CCD26870.1 - 0.002 16.9 1.4 3.1 6.4 0.0 3.1 3 0 0 3 3 3 2 MCM2/3/5 family Dynamin_N PF00350.18 CCD26870.1 - 0.0026 17.6 4.2 0.77 9.5 0.0 3.8 3 1 1 4 4 4 1 Dynamin family Rad17 PF03215.10 CCD26870.1 - 0.0039 15.9 0.1 1.4 7.4 0.0 2.8 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 CCD26870.1 - 0.004 16.8 0.0 2.8 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ArgK PF03308.11 CCD26870.1 - 0.0071 15.1 0.0 1.8 7.3 0.0 2.7 3 0 0 3 3 3 1 ArgK protein NB-ARC PF00931.17 CCD26870.1 - 0.011 14.5 0.0 3.2 6.5 0.0 2.9 2 1 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 CCD26870.1 - 0.013 15.0 0.1 4.5 6.7 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 CCD26870.1 - 0.014 14.3 0.3 6.1 5.6 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF815) SbcCD_C PF13558.1 CCD26870.1 - 0.017 15.0 0.7 1.5 8.7 0.0 3.5 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 CCD26870.1 - 0.021 13.7 0.0 0.4 9.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DAP3 PF10236.4 CCD26870.1 - 0.023 13.6 1.6 5.6 5.8 0.0 3.1 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 NTPase_1 PF03266.10 CCD26870.1 - 0.046 13.4 0.1 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 CCD26870.1 - 0.079 12.6 7.5 1.8 8.2 0.0 3.4 4 0 0 4 4 3 0 Archaeal ATPase FeoB_N PF02421.13 CCD26870.1 - 0.094 11.9 0.0 2.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF87 PF01935.12 CCD26870.1 - 0.94 9.2 8.2 13 5.5 0.0 3.9 4 1 1 5 5 4 0 Domain of unknown function DUF87 DUF2813 PF11398.3 CCD26870.1 - 4.1 6.3 7.0 4.4 6.2 0.0 3.3 5 0 0 5 5 4 0 Protein of unknown function (DUF2813) zf-HIT PF04438.11 CCD26871.1 - 0.0015 18.1 12.6 0.0026 17.3 8.7 1.3 1 0 0 1 1 1 1 HIT zinc finger DUF1642 PF07852.6 CCD26871.1 - 2.7 8.3 5.5 0.44 10.8 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1642) SRP1_TIP1 PF00660.12 CCD26872.1 - 9.3e-31 105.7 0.3 1.2e-30 105.4 0.2 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family YlzJ PF14035.1 CCD26872.1 - 0.043 13.8 0.0 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 YlzJ-like protein DNMT1-RFD PF12047.3 CCD26874.1 - 0.0052 16.4 1.8 0.13 11.9 0.1 3.4 4 0 0 4 4 4 1 Cytosine specific DNA methyltransferase replication foci domain SelP_C PF04593.9 CCD26874.1 - 0.044 13.5 0.6 0.2 11.4 0.0 2.1 2 0 0 2 2 2 0 Selenoprotein P, C terminal region HAD_2 PF13419.1 CCD26875.1 - 1.7e-21 77.2 0.0 2.2e-21 76.8 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase UAA PF08449.6 CCD26876.1 - 8.6e-17 60.9 24.1 1.1e-16 60.6 16.7 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CCD26876.1 - 2.4e-10 40.2 7.8 2.4e-10 40.2 5.4 2.7 1 1 2 3 3 3 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 CCD26876.1 - 0.0017 17.5 4.5 0.0017 17.5 3.1 1.8 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.15 CCD26876.1 - 0.0029 17.6 31.9 0.062 13.3 6.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family PHO4 PF01384.15 CCD26876.1 - 0.11 11.1 10.0 0.54 8.8 3.8 2.8 1 1 1 2 2 2 0 Phosphate transporter family Multi_Drug_Res PF00893.14 CCD26876.1 - 6 7.4 12.4 3.2 8.2 3.7 2.6 2 0 0 2 2 2 0 Small Multidrug Resistance protein COX4 PF02936.9 CCD26877.1 - 1.9e-09 37.3 0.2 2.3e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV HTH_1 PF00126.22 CCD26877.1 - 0.06 13.0 0.2 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family Claudin_2 PF13903.1 CCD26878.1 - 0.057 13.1 1.3 0.055 13.1 0.9 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction UPF0197 PF05251.7 CCD26878.1 - 0.071 13.4 3.4 0.086 13.1 2.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0197) DUF751 PF05421.6 CCD26878.1 - 1.5 9.1 4.6 0.93 9.8 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF751) SPRY PF00622.23 CCD26879.1 - 4.5e-18 65.5 1.4 1.2e-17 64.1 0.2 2.4 2 1 0 2 2 2 1 SPRY domain CLTH PF10607.4 CCD26879.1 - 9e-12 44.9 1.1 2e-11 43.7 0.7 1.7 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CCD26879.1 - 8e-05 22.2 0.0 0.00024 20.7 0.0 1.9 1 0 0 1 1 1 1 LisH SseC PF04888.7 CCD26880.1 - 0.017 14.4 8.9 0.011 15.0 3.0 2.3 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family SAPS PF04499.10 CCD26881.1 - 2.8e-151 504.3 14.0 2.8e-151 504.3 9.7 2.3 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein BatD PF13584.1 CCD26882.1 - 0.00099 17.8 0.1 0.0012 17.5 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance Acyl_transf_3 PF01757.17 CCD26882.1 - 0.0043 15.9 1.2 0.0058 15.5 0.9 1.1 1 0 0 1 1 1 1 Acyltransferase family HmuY PF14064.1 CCD26882.1 - 0.088 12.7 0.0 0.11 12.5 0.0 1.3 1 1 0 1 1 1 0 HmuY protein UL2 PF08196.6 CCD26882.1 - 0.1 12.3 2.5 0.18 11.6 1.7 1.4 1 0 0 1 1 1 0 UL2 protein DUF1077 PF06417.7 CCD26883.1 - 2.9e-45 152.6 4.5 3.7e-45 152.3 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) PsbX PF06596.6 CCD26883.1 - 0.1 12.3 0.2 0.26 10.9 0.2 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) THUMP PF02926.12 CCD26884.1 - 5e-25 88.0 0.8 8.6e-25 87.2 0.1 1.7 2 0 0 2 2 2 1 THUMP domain Sec15 PF04091.7 CCD26885.1 - 1.2e-101 340.1 13.1 1.2e-101 340.1 9.1 2.9 2 1 1 3 3 3 1 Exocyst complex subunit Sec15-like GARS_A PF01071.14 CCD26886.1 - 1e-80 269.8 0.0 1.6e-80 269.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 CCD26886.1 - 6.1e-34 116.4 0.0 3.1e-33 114.2 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 CCD26886.1 - 1.1e-28 100.1 0.0 2.7e-28 98.9 0.0 1.7 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 CCD26886.1 - 5.9e-28 96.8 0.1 1.7e-27 95.3 0.1 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 CCD26886.1 - 2.3e-17 63.0 0.8 1.7e-16 60.2 0.5 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATPgrasp_Ter PF15632.1 CCD26886.1 - 3.4e-10 39.1 0.0 6.6e-10 38.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 CCD26886.1 - 1.7e-05 24.7 0.2 5.4e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 CCD26886.1 - 8.8e-05 22.3 0.0 0.00033 20.4 0.0 2.0 1 1 0 1 1 1 1 ATP-grasp domain GIDA PF01134.17 CCD26887.1 - 4.5e-155 516.3 0.0 5.9e-155 515.9 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 CCD26887.1 - 1e-20 73.5 0.0 2.6e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 CCD26887.1 - 2.2e-06 27.6 0.2 6.3e-06 26.2 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCD26887.1 - 9.3e-05 21.6 0.1 0.00015 21.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 CCD26887.1 - 0.00016 20.6 1.3 0.28 10.0 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCD26887.1 - 0.004 17.5 0.3 0.014 15.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCD26887.1 - 0.098 11.4 5.1 0.022 13.6 0.7 1.9 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.9 CCD26887.1 - 0.21 9.9 3.5 1.4 7.3 0.3 2.6 3 0 0 3 3 3 0 HI0933-like protein CBFB_NFYA PF02045.10 CCD26888.1 - 6e-28 97.1 6.9 6e-28 97.1 4.8 2.4 2 1 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Cse1 PF08506.5 CCD26889.1 - 4.3e-165 548.7 12.6 1e-164 547.5 8.8 1.7 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 CCD26889.1 - 6.3e-102 341.0 11.6 6.3e-102 341.0 8.0 2.1 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 CCD26889.1 - 2.7e-16 59.2 2.6 2.9e-15 55.9 0.0 3.7 4 0 0 4 4 4 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CCD26889.1 - 0.00067 19.5 0.1 0.00067 19.5 0.1 4.0 5 0 0 5 5 5 1 Exportin 1-like protein APC10 PF03256.11 CCD26890.1 - 2.5e-42 144.6 0.0 3.3e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 CCD26890.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain A_deamin PF02137.13 CCD26891.1 - 2.8e-59 201.1 1.5 3.3e-59 200.9 1.0 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Plus-3 PF03126.13 CCD26892.1 - 1.9e-31 108.2 0.6 6.3e-31 106.6 0.0 2.2 2 0 0 2 2 2 1 Plus-3 domain tRNA-synt_1c PF00749.16 CCD26893.1 - 1.7e-117 391.5 0.1 2.3e-117 391.1 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CCD26893.1 - 4.5e-38 130.6 0.5 1.1e-37 129.3 0.4 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 CCD26893.1 - 1.6e-05 25.2 0.0 4.5e-05 23.8 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCD26893.1 - 0.0048 16.8 0.0 0.015 15.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCD26893.1 - 0.0084 15.9 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RAI1 PF08652.6 CCD26894.1 - 2.3e-28 97.7 0.1 4.5e-28 96.8 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease PDEase_II PF02112.10 CCD26895.1 - 1.5e-65 221.3 0.4 2.1e-65 220.9 0.3 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 CCD26895.1 - 3.7e-06 26.6 0.0 4.9e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF2420 PF10336.4 CCD26897.1 - 1.8e-33 114.5 0.2 3.3e-33 113.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) N6-adenineMlase PF10237.4 CCD26897.1 - 0.0093 15.6 0.3 0.017 14.7 0.2 1.4 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase PRO8NT PF08082.6 CCD26897.1 - 2.2 7.9 5.9 5.3 6.6 1.3 2.2 2 0 0 2 2 2 0 PRO8NT (NUC069), PrP8 N-terminal domain Sec63 PF02889.11 CCD26898.1 - 2.2e-48 165.1 2.4 3.6e-48 164.4 1.7 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 CCD26898.1 - 2e-27 95.7 0.0 5.1e-27 94.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CCD26898.1 - 2e-12 47.3 0.1 7.4e-12 45.4 0.1 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCD26898.1 - 3e-11 43.0 0.0 1.6e-10 40.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCD26898.1 - 0.00074 18.4 0.1 0.00074 18.4 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain T2SE PF00437.15 CCD26898.1 - 0.013 14.4 0.0 0.029 13.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Ppx-GppA PF02541.11 CCD26899.1 - 1e-68 231.6 0.0 1.4e-68 231.1 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Hexokinase_2 PF03727.11 CCD26900.1 - 5e-94 314.0 0.0 6.7e-94 313.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCD26900.1 - 3.3e-83 278.0 0.0 4.4e-83 277.6 0.0 1.1 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 CCD26900.1 - 0.016 14.5 0.0 0.03 13.6 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain zf-C2H2 PF00096.21 CCD26901.1 - 3.2e-10 39.7 28.0 9.2e-05 22.5 0.4 5.6 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCD26901.1 - 2.4e-09 37.0 7.2 1.8e-05 24.7 1.1 5.5 6 0 0 6 6 6 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCD26901.1 - 2e-05 24.6 29.3 0.0062 16.7 0.2 5.3 5 1 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCD26901.1 - 7.8e-05 22.6 5.0 0.00017 21.5 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCD26901.1 - 0.00034 20.7 7.3 0.019 15.1 0.1 4.2 4 0 0 4 4 4 1 Zinc-finger of C2H2 type Stork_head PF10264.4 CCD26901.1 - 0.15 12.2 1.6 0.37 11.0 0.0 2.3 3 0 0 3 3 3 0 Winged helix Storkhead-box1 domain DNA_RNApol_7kD PF03604.8 CCD26901.1 - 9.9 5.7 9.7 8.6 5.9 0.1 2.9 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit PLA2_B PF01735.13 CCD26902.1 - 7.9e-188 624.5 3.8 1.7e-187 623.5 2.6 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Peptidase_M16 PF00675.15 CCD26903.1 - 1.5e-26 92.9 0.0 2.4e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCD26903.1 - 1.1e-06 28.4 0.1 5e-06 26.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain RNA_pol_Rpc82 PF05645.8 CCD26904.1 - 1.2e-64 218.3 10.6 5.7e-64 216.1 5.0 2.3 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 CCD26904.1 - 6.6e-18 64.3 11.9 4.3e-16 58.5 0.5 3.6 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 CCD26904.1 - 0.0016 17.8 2.2 0.37 10.3 0.1 2.6 2 0 0 2 2 2 2 TFIIE alpha subunit Rio2_N PF09202.6 CCD26904.1 - 0.068 13.2 1.3 2.2 8.4 0.1 2.8 2 0 0 2 2 2 0 Rio2, N-terminal TPR_11 PF13414.1 CCD26905.1 - 4.4e-38 128.7 11.7 6.1e-08 32.2 0.0 12.4 9 3 4 13 13 13 10 TPR repeat TPR_14 PF13428.1 CCD26905.1 - 2.9e-25 86.4 1.8 0.039 14.5 0.0 13.4 10 3 5 15 15 13 6 Tetratricopeptide repeat TPR_16 PF13432.1 CCD26905.1 - 1.2e-23 83.1 0.0 0.011 16.3 0.0 9.5 8 3 3 11 11 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 CCD26905.1 - 3.5e-22 78.5 5.1 3.2e-06 27.3 0.0 8.6 8 2 2 10 10 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 CCD26905.1 - 1.4e-21 74.5 11.6 0.0047 16.7 0.0 13.5 15 1 0 15 15 15 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCD26905.1 - 2.1e-18 64.8 0.9 0.022 14.9 0.0 12.2 13 1 0 13 13 12 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCD26905.1 - 1.5e-15 56.0 15.6 0.0053 16.3 0.0 12.6 12 0 0 12 12 12 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCD26905.1 - 4.6e-14 52.1 8.7 0.19 11.6 0.0 10.2 8 3 2 10 10 10 4 Tetratricopeptide repeat Apc3 PF12895.2 CCD26905.1 - 2.8e-12 46.5 10.0 0.00024 21.1 0.0 8.4 6 3 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCD26905.1 - 1.4e-10 40.1 21.3 0.0088 15.7 0.0 11.5 14 0 0 14 14 12 3 Tetratricopeptide repeat TPR_9 PF13371.1 CCD26905.1 - 1.6e-07 31.1 0.2 1.9 8.4 0.0 6.6 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCD26905.1 - 2.6e-07 30.6 6.4 0.092 13.2 0.0 8.8 10 0 0 10 10 7 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCD26905.1 - 1.6e-05 24.3 10.5 0.84 9.5 0.0 8.7 12 0 0 12 12 10 1 Tetratricopeptide repeat TPR_5 PF12688.2 CCD26905.1 - 0.00049 20.1 0.1 0.39 10.7 0.0 3.3 3 0 0 3 3 3 1 Tetratrico peptide repeat TPR_20 PF14561.1 CCD26905.1 - 0.013 15.5 3.1 2 8.5 0.0 5.9 7 2 2 9 9 8 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 CCD26905.1 - 0.016 15.4 0.7 1.1 9.4 0.0 3.9 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation HrpB1_HrpK PF09613.5 CCD26905.1 - 0.088 12.2 0.0 0.34 10.3 0.0 2.0 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) EF-hand_7 PF13499.1 CCD26906.1 - 1.6e-10 40.9 5.2 1.7e-06 28.0 1.2 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCD26906.1 - 3.8e-08 32.5 6.6 1.5e-05 24.4 0.3 4.7 4 1 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.27 CCD26906.1 - 2.5e-07 29.4 7.2 1.8e-06 26.8 0.5 4.2 5 0 0 5 5 5 1 EF hand DUF1456 PF07308.8 CCD26906.1 - 7.9e-05 22.6 1.2 0.27 11.3 0.0 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1456) EF-hand_5 PF13202.1 CCD26906.1 - 0.00051 19.2 1.2 0.00051 19.2 0.8 2.3 2 0 0 2 2 2 1 EF hand Peptidase_C2 PF00648.16 CCD26906.1 - 0.0078 15.2 0.2 0.76 8.7 0.0 2.1 2 0 0 2 2 2 2 Calpain family cysteine protease EF-hand_8 PF13833.1 CCD26906.1 - 0.012 15.1 1.5 0.094 12.3 0.3 2.5 1 1 0 2 2 2 0 EF-hand domain pair DUF4576 PF15144.1 CCD26906.1 - 0.049 13.2 0.3 0.12 12.0 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4576) RNA_pol_Rpb6 PF01192.17 CCD26907.1 - 2.4e-23 81.6 0.3 3.7e-23 81.0 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 zf-C2H2 PF00096.21 CCD26908.1 - 2.9e-25 87.0 78.7 0.00061 19.9 1.1 9.3 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD26908.1 - 2.1e-24 84.0 73.0 0.00013 22.0 2.5 9.4 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD26908.1 - 4.6e-15 55.0 74.3 0.00017 21.7 0.1 10.2 10 0 0 10 10 10 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCD26908.1 - 1.9e-05 24.6 55.4 0.0029 17.6 0.3 8.9 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCD26908.1 - 0.00081 19.5 1.1 0.00081 19.5 0.8 8.9 9 0 0 9 9 9 3 Zinc-finger of C2H2 type CpXC PF14353.1 CCD26908.1 - 0.047 13.6 0.3 0.047 13.6 0.2 4.6 3 2 3 6 6 6 0 CpXC protein ATG13 PF10033.4 CCD26909.1 - 3.8e-59 199.9 1.0 9.9e-59 198.5 0.7 1.8 1 0 0 1 1 1 1 Autophagy-related protein 13 hDGE_amylase PF14701.1 CCD26910.1 - 1.7e-172 574.0 0.2 3e-172 573.2 0.2 1.4 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 CCD26910.1 - 2.4e-123 411.5 0.0 4.1e-123 410.7 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CCD26910.1 - 2.5e-73 246.4 0.1 5.8e-73 245.2 0.0 1.7 2 0 0 2 2 2 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 CCD26910.1 - 4.1e-23 81.0 0.1 1.2e-22 79.4 0.1 1.9 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 CCD26910.1 - 9.7e-07 28.4 0.2 0.0011 18.3 0.2 2.5 2 0 0 2 2 2 2 Alpha amylase, catalytic domain DUF445 PF04286.7 CCD26910.1 - 0.075 12.5 0.1 4.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Gly_acyl_tr_C PF08444.5 CCD26910.1 - 0.086 12.8 0.0 1.3 9.1 0.0 2.8 3 0 0 3 3 3 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Med11 PF10280.4 CCD26911.1 - 5.2e-26 90.9 3.0 6.2e-26 90.7 2.1 1.1 1 0 0 1 1 1 1 Mediator complex protein Baculo_PEP_C PF04513.7 CCD26911.1 - 0.011 15.5 0.8 0.017 14.9 0.4 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Cupredoxin_1 PF13473.1 CCD26911.1 - 0.054 13.3 0.2 0.1 12.4 0.0 1.5 2 0 0 2 2 2 0 Cupredoxin-like domain MCC-bdg_PDZ PF10506.4 CCD26911.1 - 0.072 12.9 0.1 0.14 12.0 0.1 1.5 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Globin PF00042.17 CCD26911.1 - 0.12 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Globin Glycos_transf_2 PF00535.21 CCD26912.1 - 2.3e-29 102.2 0.0 3e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 CCD26912.1 - 1.1e-08 34.4 0.0 1.5e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 CCD26912.1 - 2.6e-07 30.6 0.0 3.3e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 CKAP2_C PF15297.1 CCD26913.1 - 0.043 12.6 0.2 0.069 11.9 0.1 1.3 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus Ras PF00071.17 CCD26915.1 - 1.5e-53 180.4 0.0 8.7e-53 178.0 0.0 1.9 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CCD26915.1 - 1e-14 55.0 0.0 2.2e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCD26915.1 - 2.1e-05 23.8 0.0 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Rifin_STEVOR PF02009.11 CCD26915.1 - 0.00065 19.4 1.6 0.0008 19.1 1.1 1.1 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 CCD26915.1 - 0.0012 18.5 0.1 0.0022 17.7 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF912 PF06024.7 CCD26915.1 - 0.0031 17.5 0.3 0.0059 16.6 0.2 1.4 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Gtr1_RagA PF04670.7 CCD26915.1 - 0.019 14.1 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Shisa PF13908.1 CCD26915.1 - 0.026 14.6 0.1 0.045 13.9 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ATG22 PF11700.3 CCD26915.1 - 0.1 11.0 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Ribosomal_S14 PF00253.16 CCD26916.1 - 1.7e-17 62.5 0.2 1.3e-16 59.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e PAPS_reduct PF01507.14 CCD26917.1 - 7.7e-41 139.8 0.0 8.9e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family WD40 PF00400.27 CCD26918.1 - 4.2e-05 23.2 0.2 0.44 10.5 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ_3 PF13570.1 CCD26918.1 - 0.022 15.0 0.0 3.3 8.0 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain Pyridox_oxidase PF01243.15 CCD26920.1 - 2.4e-15 56.3 0.0 6.6e-15 54.8 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 CCD26920.1 - 0.0095 15.7 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase AAA PF00004.24 CCD26921.1 - 1.3e-44 151.5 0.0 3.2e-44 150.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CCD26921.1 - 4.7e-30 103.2 0.1 2.8e-29 100.7 0.1 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CCD26921.1 - 6e-23 80.5 3.1 4.5e-22 77.7 1.8 2.6 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 CCD26921.1 - 2.1e-06 27.8 0.6 0.00033 20.7 0.1 2.9 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 CCD26921.1 - 6.1e-06 27.0 0.1 2.5e-05 25.0 0.0 2.2 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CCD26921.1 - 1.4e-05 24.2 0.0 2.1e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCD26921.1 - 1.7e-05 24.8 0.0 4.4e-05 23.5 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain IstB_IS21 PF01695.12 CCD26921.1 - 1.9e-05 24.1 0.0 5e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 CCD26921.1 - 1.9e-05 24.4 0.0 9.3e-05 22.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 CCD26921.1 - 3.6e-05 23.6 0.1 0.00012 21.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.9 CCD26921.1 - 0.00012 21.9 0.1 0.00059 19.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 CCD26921.1 - 0.00014 21.9 0.4 0.0069 16.5 0.0 3.0 4 0 0 4 4 2 1 RNA helicase AAA_25 PF13481.1 CCD26921.1 - 0.00015 21.2 0.2 0.065 12.6 0.1 2.3 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.8 CCD26921.1 - 0.00016 20.7 0.0 0.00042 19.3 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 CCD26921.1 - 0.00026 19.8 0.0 0.00047 18.9 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 CCD26921.1 - 0.00041 20.2 0.0 0.001 18.9 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CCD26921.1 - 0.0071 16.6 0.2 0.021 15.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 CCD26921.1 - 0.012 14.6 0.2 0.24 10.4 0.0 2.5 1 1 2 3 3 3 0 Zeta toxin AAA_24 PF13479.1 CCD26921.1 - 0.014 14.9 0.0 0.032 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCD26921.1 - 0.019 14.6 0.0 0.056 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 CCD26921.1 - 0.021 14.6 1.6 0.097 12.4 0.0 2.2 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Torsin PF06309.6 CCD26921.1 - 0.021 14.7 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Torsin Arch_ATPase PF01637.13 CCD26921.1 - 0.025 14.3 0.0 0.15 11.6 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase Mg_chelatase PF01078.16 CCD26921.1 - 0.026 13.6 0.0 0.057 12.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CCD26921.1 - 0.031 13.4 0.0 0.083 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 CCD26921.1 - 0.034 13.7 0.0 0.62 9.7 0.0 2.2 1 1 1 2 2 2 0 NACHT domain KaiC PF06745.8 CCD26921.1 - 0.035 13.2 0.1 4.7 6.2 0.0 2.3 1 1 1 2 2 2 0 KaiC Sigma54_activ_2 PF14532.1 CCD26921.1 - 0.07 13.1 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CCD26921.1 - 0.071 11.9 0.0 0.13 11.0 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 CCD26921.1 - 0.079 12.4 0.0 0.39 10.1 0.0 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.1 CCD26921.1 - 0.08 12.8 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain NB-ARC PF00931.17 CCD26921.1 - 0.081 11.7 0.0 0.17 10.7 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain Cytidylate_kin2 PF13189.1 CCD26921.1 - 0.087 12.7 0.3 0.18 11.6 0.0 1.7 2 0 0 2 2 1 0 Cytidylate kinase-like family DUF2201_N PF13203.1 CCD26921.1 - 1.2 8.2 4.3 1.8 7.6 3.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain NBP1 PF08537.5 CCD26922.1 - 9.7e-26 90.7 24.1 1.9e-22 79.8 16.7 2.2 1 1 0 1 1 1 1 Fungal Nap binding protein NBP1 EMP24_GP25L PF01105.19 CCD26922.1 - 0.1 12.3 0.7 0.2 11.3 0.5 1.6 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Viral_P18 PF04521.8 CCD26922.1 - 2.3 7.6 7.4 0.72 9.3 0.1 2.4 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Fib_alpha PF08702.5 CCD26922.1 - 3.8 7.6 8.3 0.075 13.1 0.7 1.9 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF641 PF04859.7 CCD26922.1 - 9.4 6.0 9.9 5.3 6.7 0.2 2.6 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) DNA_pol_E_B PF04042.11 CCD26923.1 - 5.3e-49 166.3 1.0 5.3e-49 166.3 0.7 1.7 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Prenyltrans PF00432.16 CCD26924.1 - 9.9e-69 226.5 2.9 2.4e-14 52.5 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCD26924.1 - 5.6e-37 126.6 0.0 5.1e-14 52.6 0.0 3.8 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCD26924.1 - 4.3e-13 49.2 0.0 3e-05 23.9 0.0 3.3 1 1 3 4 4 4 4 Prenyltransferase-like A2M_comp PF07678.9 CCD26924.1 - 0.0027 16.9 0.0 0.67 9.1 0.0 3.5 3 1 1 4 4 4 1 A-macroglobulin complement component WD40 PF00400.27 CCD26925.1 - 3.5e-44 147.1 13.2 1.8e-11 43.4 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat eIF2A PF08662.6 CCD26925.1 - 0.00018 21.2 0.0 0.12 12.0 0.0 2.7 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCD26925.1 - 0.022 12.8 0.0 0.037 12.1 0.0 1.4 1 0 0 1 1 1 0 Nucleoporin Nup120/160 HDA2-3 PF11496.3 CCD26926.1 - 1.4e-84 283.4 0.4 1.4e-84 283.4 0.3 2.2 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 DUF1515 PF07439.6 CCD26926.1 - 0.0021 17.8 3.1 0.11 12.3 0.6 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1515) YgaB PF14182.1 CCD26926.1 - 0.27 11.5 21.5 0.17 12.1 3.0 4.5 2 2 2 4 4 4 0 YgaB-like protein TPR_MLP1_2 PF07926.7 CCD26926.1 - 0.34 10.6 17.3 0.35 10.6 2.0 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 CCD26926.1 - 0.49 10.2 20.2 0.32 10.8 4.7 3.2 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 CCD26926.1 - 0.61 9.9 19.0 1.7 8.5 2.7 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding FliJ PF02050.11 CCD26926.1 - 0.64 10.0 15.3 0.22 11.6 2.6 3.1 1 1 2 3 3 3 0 Flagellar FliJ protein IncA PF04156.9 CCD26926.1 - 0.78 9.3 21.0 25 4.4 14.6 2.6 1 1 0 1 1 1 0 IncA protein FliD_N PF02465.13 CCD26926.1 - 0.84 10.0 9.8 5.3 7.4 0.2 3.6 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus ThiF PF00899.16 CCD26927.1 - 6.9e-16 58.3 0.0 1.5e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 ThiF family Sec23_trunk PF04811.10 CCD26928.1 - 3e-69 233.0 0.0 4e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCD26928.1 - 1.9e-33 113.9 0.2 3.7e-33 113.0 0.2 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCD26928.1 - 1.3e-29 102.5 0.0 2.6e-29 101.5 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCD26928.1 - 2.9e-14 52.3 4.5 6.2e-14 51.2 3.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCD26928.1 - 1e-10 41.1 0.0 2.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-RanBP PF00641.13 CCD26928.1 - 0.031 13.3 0.7 0.084 11.9 0.5 1.8 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-MIZ PF02891.15 CCD26928.1 - 0.28 10.7 1.6 0.61 9.6 1.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger PIG-U PF06728.8 CCD26929.1 - 3.9e-104 348.5 47.0 4.9e-104 348.2 32.6 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 CCD26929.1 - 2.6 7.4 18.7 0.22 10.9 8.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2029) LSM PF01423.17 CCD26930.1 - 1.2e-16 59.9 0.1 1.5e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 LSM domain ORC4_C PF14629.1 CCD26933.1 - 5.5e-31 107.5 2.0 1.2e-30 106.4 1.1 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 CCD26933.1 - 1.5e-05 25.0 0.0 6.4e-05 23.0 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF3544 PF12064.3 CCD26933.1 - 0.075 12.8 0.6 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3544) Pkinase PF00069.20 CCD26934.1 - 3.8e-73 245.8 0.0 5.4e-73 245.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD26934.1 - 5.5e-31 107.5 0.0 3e-21 75.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCD26934.1 - 0.026 13.4 0.1 0.067 12.1 0.0 1.6 1 1 0 1 1 1 0 Kinase-like GTP_EFTU PF00009.22 CCD26935.1 - 1.2e-38 132.4 0.0 2e-38 131.6 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CCD26935.1 - 1.7e-36 124.1 0.3 3.7e-36 123.0 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CCD26935.1 - 5.5e-11 42.4 0.5 5.5e-11 42.4 0.3 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCD26935.1 - 0.0068 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCD26935.1 - 0.29 10.9 3.5 0.74 9.6 0.1 3.0 2 1 0 2 2 2 0 Dynamin family Zn_clus PF00172.13 CCD26936.1 - 2.3e-08 33.7 11.2 3.8e-08 33.0 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carn_acyltransf PF00755.15 CCD26938.1 - 5.5e-83 279.0 4.7 1.1e-67 228.4 1.5 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase CDC45 PF02724.9 CCD26938.1 - 9e-06 24.0 3.4 1.7e-05 23.0 2.3 1.3 1 0 0 1 1 1 1 CDC45-like protein Daxx PF03344.10 CCD26938.1 - 0.0061 15.1 5.3 0.011 14.3 3.7 1.3 1 0 0 1 1 1 1 Daxx Family Sporozoite_P67 PF05642.6 CCD26938.1 - 0.017 13.0 4.9 0.035 11.9 3.4 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_C37 PF05416.7 CCD26938.1 - 0.03 12.6 0.1 0.045 12.0 0.0 1.1 1 0 0 1 1 1 0 Southampton virus-type processing peptidase CMD PF02627.15 CCD26939.1 - 4.3e-05 23.2 0.0 0.00021 21.0 0.0 2.1 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Yippee-Mis18 PF03226.9 CCD26940.1 - 1.6e-15 56.9 1.9 1.6e-15 56.9 1.3 1.5 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly G-alpha PF00503.15 CCD26941.1 - 2.8e-108 362.0 38.9 8.1e-108 360.5 27.0 1.6 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCD26941.1 - 7.4e-17 61.1 0.7 9.9e-11 41.1 0.2 3.0 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCD26941.1 - 3.8e-06 26.2 1.7 0.00043 19.5 0.1 2.8 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region TRAP_alpha PF03896.11 CCD26941.1 - 0.0016 17.4 7.0 0.0016 17.4 4.9 1.9 2 1 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 CCD26941.1 - 0.0018 16.4 8.7 0.0018 16.4 6.0 2.1 2 0 0 2 2 2 1 CDC45-like protein Miro PF08477.8 CCD26941.1 - 0.0074 16.7 0.2 1.4 9.3 0.0 3.1 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 CCD26941.1 - 0.025 14.1 0.9 0.052 13.0 0.6 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CCD26941.1 - 0.058 12.8 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Med17 PF10156.4 CCD26942.1 - 1.4e-123 412.6 40.2 4.4e-123 410.9 27.8 1.7 1 1 0 1 1 1 1 Subunit 17 of Mediator complex MCPVI PF02993.9 CCD26942.1 - 1 9.4 6.1 2.5 8.1 4.2 1.6 1 0 0 1 1 1 0 Minor capsid protein VI P5CR_dimer PF14748.1 CCD26943.1 - 1.1e-33 115.4 0.2 1.9e-33 114.6 0.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CCD26943.1 - 4.2e-11 43.1 0.3 1.4e-10 41.4 0.1 2.0 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 CCD26943.1 - 0.046 13.6 0.1 0.11 12.4 0.0 1.8 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_Gly3P_dh_N PF01210.18 CCD26943.1 - 0.064 12.9 0.2 0.13 11.9 0.1 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AAA-ATPase_like PF09820.4 CCD26943.1 - 0.083 12.0 0.0 0.11 11.5 0.0 1.1 1 0 0 1 1 1 0 Predicted AAA-ATPase Ribosomal_S7 PF00177.16 CCD26944.1 - 6.9e-39 132.7 1.8 9.2e-39 132.3 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e EF-hand_4 PF12763.2 CCD26945.1 - 2.1e-31 107.7 3.0 4.3e-10 39.2 0.3 4.6 4 0 0 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CCD26945.1 - 2.4e-11 43.6 0.7 0.0012 18.9 0.0 4.5 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 CCD26945.1 - 5.2e-09 34.7 0.2 0.00081 18.5 0.0 4.4 3 0 0 3 3 3 2 EF hand UBA PF00627.26 CCD26945.1 - 1.3e-08 34.4 0.1 1.3e-08 34.4 0.1 2.4 3 0 0 3 3 3 1 UBA/TS-N domain EF-hand_6 PF13405.1 CCD26945.1 - 0.00096 18.8 0.1 2 8.4 0.0 4.3 4 0 0 4 4 4 1 EF-hand domain EF-hand_8 PF13833.1 CCD26945.1 - 0.0014 18.1 0.1 2.3 7.8 0.0 4.0 4 0 0 4 4 4 1 EF-hand domain pair UBA_4 PF14555.1 CCD26945.1 - 0.002 17.5 0.2 0.002 17.5 0.2 2.3 2 0 0 2 2 2 1 UBA-like domain DUF3584 PF12128.3 CCD26945.1 - 3.6 4.7 65.0 0.0025 15.2 34.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) VanZ PF04892.7 CCD26947.1 - 2.7e-07 30.5 6.0 3.5e-07 30.2 1.9 2.1 1 1 1 2 2 2 1 VanZ like family DUF989 PF06181.6 CCD26947.1 - 0.046 12.8 0.0 0.079 12.0 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF989) ABC2_membrane_5 PF13346.1 CCD26947.1 - 1.5 8.0 7.9 5 6.3 0.6 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein PPP4R2 PF09184.6 CCD26948.1 - 7.5e-35 120.8 40.1 7.5e-35 120.8 27.8 3.2 1 1 2 3 3 3 1 PPP4R2 Peptidase_M16_C PF05193.16 CCD26949.1 - 1e-27 96.9 0.1 1.9e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCD26949.1 - 1.3e-24 86.6 0.2 2.5e-24 85.7 0.1 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Transp_cyt_pur PF02133.10 CCD26951.1 - 1.3e-156 521.5 41.8 1.5e-156 521.3 29.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Proteasome PF00227.21 CCD26952.1 - 3.3e-35 121.0 0.0 1.9e-34 118.6 0.0 1.8 1 1 0 1 1 1 1 Proteasome subunit ER_lumen_recept PF00810.13 CCD26953.1 - 1e-48 165.5 14.0 1.5e-48 165.0 9.7 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor Oxidored_q3 PF00499.15 CCD26954.1 - 0.065 13.0 1.7 0.074 12.8 1.2 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 CTP_synth_N PF06418.9 CCD26955.1 - 5.6e-121 402.8 0.4 8.1e-121 402.3 0.3 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CCD26955.1 - 2.1e-55 187.1 0.0 3.2e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCD26955.1 - 0.00012 21.5 0.0 0.00041 19.8 0.0 1.9 2 0 0 2 2 2 1 Peptidase C26 CbiA PF01656.18 CCD26955.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PAP1 PF08601.5 CCD26956.1 - 0.048 13.3 8.2 0.063 12.9 5.7 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Bd3614_N PF14442.1 CCD26956.1 - 0.095 12.6 1.6 0.73 9.8 2.2 1.7 2 0 0 2 2 2 0 Bd3614-like deaminase N-terminal DUF2457 PF10446.4 CCD26956.1 - 0.55 8.9 12.0 0.93 8.1 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) TMEM192 PF14802.1 CCD26956.1 - 0.56 9.0 5.4 0.11 11.2 1.3 1.6 2 0 0 2 2 2 0 TMEM192 family Astro_capsid PF03115.9 CCD26956.1 - 1 7.4 7.3 1.1 7.4 4.3 1.3 1 1 0 1 1 1 0 Astrovirus capsid protein precursor Nup54 PF13874.1 CCD26956.1 - 1.7 8.3 19.2 0.44 10.1 5.0 2.5 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 DUF501 PF04417.7 CCD26956.1 - 8.1 6.2 6.6 2.3 8.0 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF501) PBP1_TM PF14812.1 CCD26956.1 - 9.4 6.6 13.6 0.85 9.9 5.6 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SAC3_GANP PF03399.11 CCD26957.1 - 2.6e-48 164.2 10.0 4.7e-48 163.4 6.9 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCD26957.1 - 7.2e-07 29.0 4.4 7.2e-07 29.0 3.1 2.0 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 Paramyxo_ncap PF00973.14 CCD26957.1 - 8.6 4.9 8.5 12 4.3 5.9 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein PX PF00787.19 CCD26958.1 - 2.5e-07 30.4 0.2 7.1e-07 29.0 0.2 1.8 1 0 0 1 1 1 1 PX domain Syntaxin-6_N PF09177.6 CCD26958.1 - 1 9.8 5.3 1.5 9.2 0.1 3.5 4 1 0 4 4 4 0 Syntaxin 6, N-terminal Ribosomal_L37ae PF01780.14 CCD26959.1 - 3.4e-39 132.6 9.3 3.7e-39 132.4 6.5 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rep_fac-A_C PF08646.5 CCD26959.1 - 0.0073 16.0 0.3 0.0084 15.8 0.2 1.2 1 0 0 1 1 1 1 Replication factor-A C terminal domain CarbpepA_inh PF02977.10 CCD26959.1 - 0.023 14.2 1.3 0.023 14.2 0.9 2.1 1 1 1 2 2 2 0 Carboxypeptidase A inhibitor Zn_Tnp_IS1595 PF12760.2 CCD26959.1 - 0.024 14.4 2.5 0.039 13.7 1.7 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF1364 PF07102.7 CCD26959.1 - 0.037 13.8 1.1 0.048 13.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Sgf11 PF08209.6 CCD26959.1 - 0.081 12.2 0.3 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-H2C2_2 PF13465.1 CCD26959.1 - 0.09 13.1 0.6 1.8 8.9 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Elf1 PF05129.8 CCD26959.1 - 0.26 11.0 2.6 0.61 9.8 1.8 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like OrfB_Zn_ribbon PF07282.6 CCD26959.1 - 0.33 10.6 2.3 0.54 9.9 1.5 1.4 1 1 0 1 1 1 0 Putative transposase DNA-binding domain YyzF PF14116.1 CCD26959.1 - 0.44 10.5 0.2 0.44 10.5 0.1 1.6 2 0 0 2 2 2 0 YyzF-like protein zf-C4_ClpX PF06689.8 CCD26959.1 - 1.1 8.7 4.7 2.6 7.6 3.3 1.7 1 1 0 1 1 1 0 ClpX C4-type zinc finger zf-BED PF02892.10 CCD26959.1 - 1.8 8.3 4.7 5.1 6.9 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger Anillin PF08174.6 CCD26960.1 - 0.0054 16.7 1.9 0.034 14.1 0.3 2.9 2 1 0 2 2 2 1 Cell division protein anillin M-factor PF03855.8 CCD26960.1 - 4 7.5 7.4 1.4 8.9 1.6 2.7 2 0 0 2 2 2 0 M-factor PUF PF00806.14 CCD26961.1 - 2e-24 83.6 9.8 0.00016 20.9 0.1 6.9 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat RRM_5 PF13893.1 CCD26961.1 - 4.4e-06 26.4 0.0 9.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCD26961.1 - 0.00012 21.6 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF-5_eIF-2B PF01873.12 CCD26962.1 - 2.7e-42 143.3 0.0 5.5e-42 142.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CCD26962.1 - 2.3e-26 91.5 0.1 9.4e-26 89.5 0.0 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon TPR_2 PF07719.12 CCD26963.1 - 1.1e-06 28.0 0.1 1.2e-05 24.8 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCD26963.1 - 3.4e-05 23.3 2.4 9.4e-05 21.9 0.0 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCD26963.1 - 0.00025 20.6 0.2 0.00087 18.8 0.1 2.0 2 0 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 CCD26963.1 - 0.00066 19.1 0.1 0.0027 17.2 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCD26963.1 - 0.0034 18.0 0.0 0.34 11.6 0.0 2.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCD26963.1 - 0.01 16.2 0.9 7.3 7.2 0.0 3.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 CCD26963.1 - 0.012 15.6 0.2 0.11 12.6 0.0 2.5 2 2 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 CCD26963.1 - 0.016 15.1 0.3 0.34 10.8 0.1 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCD26963.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCD26963.1 - 0.069 13.3 0.1 5.6 7.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Mem_trans PF03547.13 CCD26964.1 - 2.6e-46 157.6 0.1 3.4e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Membrane transport protein Aldo_ket_red PF00248.16 CCD26965.1 - 7.1e-64 215.3 0.0 8e-64 215.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.7 CCD26965.1 - 0.051 12.9 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) GvpK PF05121.7 CCD26965.1 - 0.07 12.9 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Gas vesicle protein K Stm1_N PF09598.5 CCD26966.1 - 7e-18 65.0 1.9 7e-18 65.0 1.3 3.8 3 3 1 4 4 4 1 Stm1 Stb3 PF10330.4 CCD26967.1 - 7.2e-29 99.3 0.8 1.6e-28 98.1 0.0 2.1 3 0 0 3 3 3 1 Putative Sin3 binding protein Vac_ImportDeg PF09783.4 CCD26967.1 - 0.12 11.8 0.1 0.12 11.8 0.1 2.3 2 0 0 2 2 2 0 Vacuolar import and degradation protein CDC37_N PF03234.9 CCD26968.1 - 8e-64 215.2 16.8 8e-64 215.2 11.7 3.1 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 CCD26968.1 - 2.4e-41 141.0 5.9 2.4e-41 141.0 4.1 2.9 3 0 0 3 3 3 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 CCD26968.1 - 2.8e-20 72.0 6.6 3.5e-20 71.7 2.8 2.6 2 0 0 2 2 2 1 Cdc37 C terminal domain CKAP2_C PF15297.1 CCD26969.1 - 0.12 11.1 0.1 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF444 PF04285.7 CCD26970.1 - 4 5.9 4.9 5.9 5.4 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) TFIID_30kDa PF03540.8 CCD26971.1 - 7e-27 93.0 0.1 1.1e-26 92.4 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit SMN PF06003.7 CCD26971.1 - 1.7 7.6 5.6 0.21 10.6 1.0 1.5 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Sec5 PF15469.1 CCD26972.1 - 5.6e-50 169.6 12.0 5.6e-50 169.6 8.3 3.4 4 0 0 4 4 4 1 Exocyst complex component Sec5 Vps51 PF08700.6 CCD26972.1 - 0.0043 16.8 5.7 0.0043 16.8 4.0 3.7 2 1 1 3 3 3 1 Vps51/Vps67 COG2 PF06148.6 CCD26972.1 - 0.04 13.7 9.5 0.017 14.9 4.0 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 WD40 PF00400.27 CCD26973.1 - 5.4e-05 22.9 0.7 0.026 14.3 0.2 4.2 4 1 0 4 4 4 1 WD domain, G-beta repeat CPSF_A PF03178.10 CCD26973.1 - 0.0061 15.6 0.6 0.023 13.8 0.0 2.0 2 1 1 3 3 3 1 CPSF A subunit region NAD_binding_1 PF00175.16 CCD26973.1 - 0.034 14.7 0.0 0.56 10.8 0.0 2.3 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain zf-CCHC_4 PF14392.1 CCD26974.1 - 0.00052 19.6 0.4 0.001 18.6 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle Sec1 PF00995.18 CCD26975.1 - 1.9e-98 330.5 7.7 2.3e-98 330.3 5.3 1.0 1 0 0 1 1 1 1 Sec1 family DUF3113 PF11310.3 CCD26975.1 - 0.045 13.4 1.6 0.12 12.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3113) Cwf_Cwc_15 PF04889.7 CCD26976.1 - 1.7e-15 57.3 10.1 2.7e-09 37.1 1.2 2.2 2 1 0 2 2 2 2 Cwf15/Cwc15 cell cycle control protein SH3_1 PF00018.23 CCD26977.1 - 1.1e-12 47.1 2.4 1.2e-12 46.9 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CCD26977.1 - 1.5e-11 43.7 1.4 2.6e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CCD26977.1 - 1.2e-05 24.7 0.0 2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TPR_2 PF07719.12 CCD26978.1 - 8.3e-07 28.4 1.0 0.11 12.4 0.0 4.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCD26978.1 - 8.4e-06 26.0 2.0 0.0071 16.6 0.1 3.2 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCD26978.1 - 2e-05 24.1 0.7 0.12 12.0 0.0 3.5 3 1 0 3 3 3 2 TPR repeat Apc3 PF12895.2 CCD26978.1 - 5.5e-05 23.2 0.0 0.13 12.4 0.0 3.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 CCD26978.1 - 7.2e-05 23.0 0.0 0.37 11.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.7 CCD26978.1 - 0.00036 20.2 0.0 2.1 8.2 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCD26978.1 - 0.0015 18.0 0.3 0.45 10.2 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCD26978.1 - 0.0023 17.8 0.3 0.85 9.5 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCD26978.1 - 0.0057 16.3 0.1 1.5 8.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCD26978.1 - 0.0057 17.2 0.0 0.28 11.9 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCD26978.1 - 0.0072 16.0 0.2 5.1 7.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 CCD26978.1 - 0.012 15.5 0.7 0.09 12.7 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCD26978.1 - 0.016 15.3 0.0 2.8 8.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 CCD26978.1 - 0.14 11.2 0.0 0.39 9.7 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat AA_permease PF00324.16 CCD26979.1 - 2.6e-75 253.5 43.3 3.9e-75 253.0 30.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCD26979.1 - 7.9e-29 100.4 51.9 2.8e-28 98.6 36.0 1.7 1 1 0 1 1 1 1 Amino acid permease DUF2618 PF10940.3 CCD26979.1 - 0.026 14.3 0.0 0.092 12.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2618) SAC3_GANP PF03399.11 CCD26980.1 - 9e-58 195.1 0.7 3.9e-57 193.1 0.5 2.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SAC3 PF12209.3 CCD26980.1 - 5.2e-16 58.5 1.3 5.2e-16 58.5 0.9 2.8 3 0 0 3 3 3 1 Leucine permease transcriptional regulator helical domain Semialdhyde_dhC PF02774.13 CCD26981.1 - 1e-44 152.6 0.0 1.6e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 CCD26981.1 - 8.2e-31 106.8 0.0 1.4e-30 106.0 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 CCD26981.1 - 0.024 15.1 0.0 0.065 13.7 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 CCD26981.1 - 0.047 12.6 0.2 0.085 11.8 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase DapB_N PF01113.15 CCD26981.1 - 0.095 12.6 0.0 0.21 11.5 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus RNA_polI_A14 PF08203.6 CCD26982.1 - 6.1e-23 80.8 2.0 6.5e-23 80.7 0.1 1.9 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 Pro_isomerase PF00160.16 CCD26983.1 - 2.2e-47 161.1 0.0 2.4e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 CCD26983.1 - 0.078 12.8 0.0 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin domain DUF3589 PF12141.3 CCD26984.1 - 1.3e-86 290.8 5.5 7.4e-86 288.3 3.8 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) ENTH PF01417.15 CCD26985.1 - 4.3e-31 107.3 0.7 1.9e-30 105.2 0.0 2.3 2 0 0 2 2 2 1 ENTH domain DUF1189 PF06691.6 CCD26985.1 - 0.005 16.1 0.1 0.0085 15.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1189) Thymopoietin PF08198.6 CCD26985.1 - 0.039 13.4 0.2 0.099 12.1 0.1 1.7 1 0 0 1 1 1 0 Thymopoietin protein RWD PF05773.17 CCD26986.1 - 1.3e-24 86.2 4.0 2.6e-24 85.2 2.8 1.5 1 0 0 1 1 1 1 RWD domain zf-CCCH PF00642.19 CCD26987.1 - 1.3e-18 66.2 16.9 3e-10 39.5 2.2 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CCD26987.1 - 0.029 14.3 1.3 0.029 14.3 0.9 2.5 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Mcp5_PH PF12814.2 CCD26988.1 - 1.6e-39 134.5 0.0 5.2e-39 132.9 0.0 2.0 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology 2-oxoacid_dh PF00198.18 CCD26989.1 - 2.4e-78 262.5 0.0 3.4e-78 262.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCD26989.1 - 1.2e-16 60.0 0.7 2.1e-16 59.2 0.5 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 CCD26989.1 - 2.6e-05 23.5 0.9 0.00061 19.0 0.1 2.2 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 CCD26989.1 - 6.4e-05 22.5 0.9 0.054 13.1 0.1 2.4 1 1 1 2 2 2 2 Biotin-lipoyl like GCV_H PF01597.14 CCD26989.1 - 0.00027 20.6 0.1 0.00064 19.3 0.1 1.7 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 CCD26989.1 - 0.0091 15.7 0.0 0.028 14.1 0.0 1.8 1 1 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD PF00529.15 CCD26989.1 - 0.013 14.8 0.5 5.5 6.2 0.0 2.7 1 1 1 3 3 3 0 HlyD family secretion protein HlyD_3 PF13437.1 CCD26989.1 - 0.013 15.8 0.1 0.12 12.7 0.0 2.2 1 1 1 2 2 2 0 HlyD family secretion protein PYNP_C PF07831.8 CCD26989.1 - 0.14 11.6 0.1 1.5 8.3 0.0 2.3 1 1 1 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF2413 PF10310.4 CCD26989.1 - 0.63 8.7 8.6 0.89 8.2 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CPSF100_C PF13299.1 CCD26989.1 - 2.2 8.4 8.4 0.29 11.3 1.3 2.4 2 1 1 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Choline_kinase PF01633.15 CCD26990.1 - 1.4e-49 168.5 0.1 2.2e-49 167.8 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CCD26990.1 - 5.7e-09 36.0 0.0 9.5e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kin_N PF04428.9 CCD26990.1 - 0.00017 21.0 0.0 0.00048 19.5 0.0 1.7 1 0 0 1 1 1 1 Choline kinase N terminus EcKinase PF02958.15 CCD26990.1 - 0.00043 19.5 0.1 0.00066 18.8 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase zf-C2H2 PF00096.21 CCD26991.1 - 3.9e-07 30.0 14.8 0.0046 17.2 2.1 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCD26991.1 - 0.00016 21.8 18.2 0.00052 20.1 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCD26991.1 - 0.0017 18.5 10.8 1.7 9.1 0.5 3.7 2 1 1 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCD26991.1 - 0.0049 16.7 3.1 0.5 10.3 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger Bunya_G2 PF03563.8 CCD26991.1 - 0.015 14.2 1.5 0.026 13.4 1.0 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 AT_hook PF02178.14 CCD26991.1 - 0.13 12.0 5.1 0.36 10.6 3.5 1.9 1 0 0 1 1 1 0 AT hook motif zf-DHHC PF01529.15 CCD26992.1 - 1.3e-27 96.3 18.5 1.3e-27 96.3 12.8 2.5 1 1 1 2 2 2 1 DHHC palmitoyltransferase Zip PF02535.17 CCD26993.1 - 1.4e-64 218.1 7.9 1.6e-64 217.9 5.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter TFIID_20kDa PF03847.8 CCD26994.1 - 1.8e-31 108.2 0.2 3.8e-31 107.1 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CCD26994.1 - 0.0021 18.1 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Ribosomal_60s PF00428.14 CCD26994.1 - 2.2 8.7 17.8 1.9 8.9 0.4 3.8 4 0 0 4 4 4 0 60s Acidic ribosomal protein K_channel_TID PF07941.6 CCD26994.1 - 3 8.1 19.8 8.2 6.7 2.1 4.0 4 0 0 4 4 4 0 Potassium channel Kv1.4 tandem inactivation domain Asp PF00026.18 CCD26995.1 - 4.3e-70 236.4 10.6 7.8e-70 235.6 5.7 2.2 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCD26995.1 - 2.1e-05 24.5 9.1 0.014 15.3 0.0 3.7 3 1 1 4 4 4 2 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCD26995.1 - 0.0015 18.1 0.5 0.069 12.7 0.4 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal EXS PF03124.9 CCD26995.1 - 0.0087 15.1 0.1 0.014 14.4 0.1 1.3 1 0 0 1 1 1 1 EXS family WD40 PF00400.27 CCD26996.1 - 4.1e-21 73.9 16.1 1e-05 25.2 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat Dopey_N PF04118.9 CCD26997.1 - 6.3e-113 376.6 5.1 6.3e-113 376.6 3.5 3.0 2 1 0 2 2 2 2 Dopey, N-terminal Methyltransf_26 PF13659.1 CCD26998.1 - 9.5e-13 48.2 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCD26998.1 - 9e-07 28.4 0.0 4.3e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CCD26998.1 - 0.00095 18.9 0.0 0.011 15.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCD26998.1 - 0.0011 18.5 0.0 0.0031 17.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain DUF2431 PF10354.4 CCD26998.1 - 0.0048 16.8 0.0 0.0075 16.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) Methyltransf_12 PF08242.7 CCD26998.1 - 0.0053 17.2 0.0 0.058 13.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ubiquitin PF00240.18 CCD26999.1 - 1.6e-22 78.6 0.1 1.8e-22 78.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCD26999.1 - 1.3e-15 56.8 0.1 1.4e-15 56.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 CCD26999.1 - 0.00018 21.3 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 GLUT4 regulating protein TUG Ubiquitin_2 PF14560.1 CCD26999.1 - 0.0013 18.8 0.1 0.0043 17.2 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain efThoc1 PF11957.3 CCD27001.1 - 3.1e-68 230.4 31.9 3.1e-68 230.4 22.1 1.8 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor 7tm_2 PF00002.19 CCD27002.1 - 0.048 12.7 0.7 0.087 11.8 0.5 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (Secretin family) Tymo_45kd_70kd PF03251.8 CCD27003.1 - 0.012 14.3 11.5 0.034 12.8 3.4 2.6 3 0 0 3 3 3 0 Tymovirus 45/70Kd protein Flu_C_NS2 PF03555.9 CCD27003.1 - 0.065 13.1 0.5 0.17 11.8 0.1 1.9 2 0 0 2 2 2 0 Influenza C non-structural protein (NS2) ACP53EA PF06313.6 CCD27004.1 - 0.01 15.7 0.7 0.1 12.5 0.0 2.9 3 0 0 3 3 3 0 Drosophila ACP53EA protein F-box-like PF12937.2 CCD27004.1 - 0.049 13.3 0.2 0.16 11.7 0.1 2.0 1 0 0 1 1 1 0 F-box-like BTB_2 PF02214.17 CCD27005.1 - 3.1e-08 33.7 0.2 0.0038 17.4 0.0 3.3 2 1 0 2 2 2 2 BTB/POZ domain Flocculin_t3 PF13928.1 CCD27006.1 - 1.3e-10 41.2 18.9 1.3e-10 41.2 13.1 2.7 2 1 0 2 2 2 1 Flocculin type 3 repeat Myco_19_kDa PF05481.7 CCD27006.1 - 2.9 7.6 8.2 0.77 9.5 3.3 1.7 1 1 1 2 2 2 0 Mycobacterium 19 kDa lipoprotein antigen ABC_membrane PF00664.18 CCD27007.1 - 4.2e-90 301.9 36.7 9.3e-51 172.8 8.0 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCD27007.1 - 2.8e-51 173.4 0.2 1.5e-31 109.5 0.0 2.9 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCD27007.1 - 6.6e-09 35.3 7.0 0.0033 16.6 0.9 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCD27007.1 - 1e-08 35.3 0.1 0.0065 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 CCD27007.1 - 1.5e-07 30.9 0.0 0.015 14.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CCD27007.1 - 4.2e-07 30.4 0.4 0.0028 18.0 0.0 3.4 3 1 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 CCD27007.1 - 7.4e-06 25.9 0.1 0.14 12.1 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 CCD27007.1 - 1.2e-05 24.6 0.2 0.092 12.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CCD27007.1 - 1.4e-05 25.2 6.6 0.49 10.3 0.0 5.1 3 2 1 4 4 4 2 AAA domain DUF258 PF03193.11 CCD27007.1 - 0.00021 20.5 0.0 0.38 9.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 CCD27007.1 - 0.00026 21.4 0.3 0.66 10.4 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein AAA_10 PF12846.2 CCD27007.1 - 0.00044 19.7 0.9 1.9 7.8 0.1 3.3 3 0 0 3 3 3 1 AAA-like domain DUF87 PF01935.12 CCD27007.1 - 0.0029 17.4 1.5 0.44 10.3 0.1 2.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_17 PF13207.1 CCD27007.1 - 0.0043 17.8 0.2 1.8 9.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCD27007.1 - 0.0043 16.7 1.0 0.02 14.5 0.0 2.6 4 0 0 4 4 3 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 CCD27007.1 - 0.0059 16.1 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AIG1 PF04548.11 CCD27007.1 - 0.011 14.8 1.1 0.29 10.2 0.0 2.9 3 0 0 3 3 3 0 AIG1 family Zeta_toxin PF06414.7 CCD27007.1 - 0.022 13.8 0.1 6.4 5.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.18 CCD27007.1 - 0.022 14.5 0.8 1.2 8.8 0.0 2.9 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 CCD27007.1 - 0.031 14.5 0.1 2.2 8.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CCD27007.1 - 0.032 14.3 1.3 2.5 8.2 0.0 3.1 2 1 0 2 2 2 0 AAA domain Root_cap PF06830.6 CCD27007.1 - 0.035 13.9 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Root cap T2SE PF00437.15 CCD27007.1 - 0.044 12.6 0.1 0.33 9.7 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein TrwB_AAD_bind PF10412.4 CCD27007.1 - 0.05 12.2 0.2 2.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 CCD27007.1 - 0.068 12.8 1.4 9 5.9 0.1 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 CCD27007.1 - 0.083 12.3 0.4 1 8.7 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LRR_4 PF12799.2 CCD27007.1 - 0.11 12.1 2.0 0.28 10.8 0.1 2.5 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) ATP-synt_ab PF00006.20 CCD27007.1 - 0.16 11.4 0.1 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 CCD27007.1 - 0.26 10.8 0.4 32 4.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain Rgp1 PF08737.5 CCD27009.1 - 2.9e-87 293.4 13.3 2.9e-87 293.4 9.2 1.9 2 0 0 2 2 2 1 Rgp1 WD40 PF00400.27 CCD27010.1 - 5.6e-17 60.9 17.0 1.5e-07 30.9 0.2 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-rbx1 PF12678.2 CCD27010.1 - 0.0096 16.0 6.4 0.022 14.8 4.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCD27010.1 - 0.013 15.3 9.0 0.027 14.3 6.2 1.5 1 0 0 1 1 1 0 Ring finger domain RWD PF05773.17 CCD27010.1 - 0.024 14.5 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 RWD domain zf-C3HC4_2 PF13923.1 CCD27010.1 - 0.026 14.5 10.5 0.053 13.5 7.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Lyase_1 PF00206.15 CCD27010.1 - 0.041 13.0 0.1 0.079 12.1 0.1 1.3 1 0 0 1 1 1 0 Lyase Prok-RING_1 PF14446.1 CCD27010.1 - 0.096 12.4 7.1 0.2 11.4 4.9 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 CCD27010.1 - 0.099 12.3 6.5 0.21 11.3 4.5 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_3 PF07649.7 CCD27010.1 - 0.12 12.4 4.4 0.26 11.3 3.1 1.6 1 0 0 1 1 1 0 C1-like domain EPSP_synthase PF00275.15 CCD27011.1 - 1.4e-134 448.7 0.0 2e-134 448.1 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CCD27011.1 - 5e-97 323.8 0.0 7.6e-97 323.3 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 CCD27011.1 - 1.5e-06 27.6 0.1 2.8e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Abhydrolase_6 PF12697.2 CCD27012.1 - 5.1e-23 82.1 0.0 8.3e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD27012.1 - 5.9e-13 48.9 0.0 3.6e-11 43.0 0.0 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCD27012.1 - 2.5e-12 46.7 0.0 5e-12 45.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CCD27012.1 - 2.4e-09 36.6 3.1 2.3e-08 33.4 2.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 CCD27012.1 - 0.00088 18.7 0.0 0.0015 17.9 0.0 1.6 1 1 0 1 1 1 1 Putative esterase DUF2305 PF10230.4 CCD27012.1 - 0.001 18.5 0.0 0.0046 16.4 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 CCD27012.1 - 0.0015 18.8 0.0 0.0045 17.2 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase PF07224.6 CCD27012.1 - 0.0053 15.5 0.0 0.0084 14.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase PGAP1 PF07819.8 CCD27012.1 - 0.0057 16.2 0.0 0.017 14.6 0.0 1.7 1 1 1 2 2 2 1 PGAP1-like protein Ser_hydrolase PF06821.8 CCD27012.1 - 0.014 15.0 0.0 0.045 13.3 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase Ndr PF03096.9 CCD27012.1 - 0.02 13.4 0.0 0.36 9.2 0.0 2.1 2 0 0 2 2 2 0 Ndr family DLH PF01738.13 CCD27012.1 - 0.023 14.0 0.0 0.09 12.0 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 CCD27012.1 - 0.024 14.2 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCD27013.1 - 1.3e-18 67.7 0.0 2e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD27013.1 - 5.7e-14 52.2 0.0 1e-12 48.1 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCD27013.1 - 1.2e-10 41.3 0.0 2.1e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CCD27013.1 - 1.9e-08 33.6 0.2 4e-08 32.6 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 CCD27013.1 - 0.00089 19.5 0.0 0.013 15.7 0.0 2.4 2 0 0 2 2 2 1 Thioesterase domain Chlorophyllase PF07224.6 CCD27013.1 - 0.003 16.4 0.0 0.0055 15.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.15 CCD27013.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Ndr PF03096.9 CCD27013.1 - 0.0097 14.4 0.0 0.03 12.8 0.0 1.8 2 0 0 2 2 2 1 Ndr family PGAP1 PF07819.8 CCD27013.1 - 0.012 15.1 0.2 0.085 12.4 0.0 2.2 2 1 0 2 2 2 0 PGAP1-like protein Abhydrolase_3 PF07859.8 CCD27013.1 - 0.013 15.0 0.0 0.52 9.8 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2305 PF10230.4 CCD27013.1 - 0.013 14.8 0.2 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 CCD27013.1 - 0.026 14.1 0.0 0.091 12.3 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase Chlorophyllase2 PF12740.2 CCD27013.1 - 0.045 12.6 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF2841 PF11001.3 CCD27014.1 - 3.5e-36 123.8 1.5 6.4e-36 122.9 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) HLH PF00010.21 CCD27015.1 - 0.025 14.2 0.8 0.074 12.7 0.6 1.9 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain PRESAN PF09687.5 CCD27015.1 - 1.2 9.2 7.1 0.29 11.2 2.1 2.0 2 0 0 2 2 2 0 Plasmodium RESA N-terminal Pkinase PF00069.20 CCD27017.1 - 1.1e-70 237.7 4.4 1.6e-70 237.2 1.0 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD27017.1 - 3.4e-39 134.4 0.2 4.5e-36 124.2 0.0 2.6 1 1 1 2 2 2 2 Protein tyrosine kinase KA1 PF02149.14 CCD27017.1 - 3.6e-19 67.9 0.3 1.5e-18 65.9 0.0 2.2 3 0 0 3 3 3 1 Kinase associated domain 1 Kinase-like PF14531.1 CCD27017.1 - 1.6e-08 33.8 0.3 7.1e-08 31.7 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 CCD27017.1 - 0.00014 20.9 0.0 0.00035 19.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD27017.1 - 0.0028 17.4 0.0 0.01 15.5 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family CBFD_NFYB_HMF PF00808.18 CCD27018.1 - 4.3e-05 23.4 0.1 9e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCD27018.1 - 0.046 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 YfhO PF09586.5 CCD27018.1 - 1.4 6.8 4.1 1.7 6.5 2.8 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF1675 PF07897.6 CCD27018.1 - 4.1 7.1 12.5 7.8 6.2 8.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Apc4 PF12896.2 CCD27019.1 - 1.5e-12 47.2 10.3 3e-11 43.0 7.2 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 MFS_1 PF07690.11 CCD27020.1 - 1.9e-13 49.8 40.9 1.9e-13 49.8 28.4 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily RELT PF12606.3 CCD27020.1 - 0.13 11.3 0.1 0.13 11.3 0.1 4.5 5 0 0 5 5 5 0 Tumour necrosis factor receptor superfamily member 19 TRM PF02005.11 CCD27022.1 - 2.6e-143 477.4 0.1 3.4e-143 477.1 0.0 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 CCD27022.1 - 0.00017 21.2 0.1 0.00032 20.3 0.1 1.5 1 0 0 1 1 1 1 Met-10+ like-protein DUF2067 PF09840.4 CCD27022.1 - 0.027 14.0 0.0 0.092 12.2 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) SUI1 PF01253.17 CCD27023.1 - 1.8e-12 46.8 0.2 6.3e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 Translation initiation factor SUI1 SWIB PF02201.13 CCD27023.1 - 5e-05 22.9 0.2 0.00013 21.5 0.2 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain Med4 PF10018.4 CCD27024.1 - 2.5e-35 121.6 5.9 2.5e-35 121.6 4.1 2.4 3 0 0 3 3 3 1 Vitamin-D-receptor interacting Mediator subunit 4 SPT6_acidic PF14632.1 CCD27024.1 - 0.82 9.8 17.0 2.2 8.5 11.8 1.7 1 0 0 1 1 1 0 Acidic N-terminal SPT6 Zip PF02535.17 CCD27024.1 - 5.9 5.7 4.9 8.8 5.2 3.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Ribosomal_L1 PF00687.16 CCD27025.1 - 7e-21 74.5 0.9 8.3e-21 74.3 0.2 1.5 2 1 0 2 2 2 1 Ribosomal protein L1p/L10e family Ribosomal_L34 PF00468.12 CCD27026.1 - 1.1e-17 63.4 6.7 1.7e-17 62.7 4.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L34 Cgr1 PF03879.9 CCD27026.1 - 0.015 15.4 1.0 0.022 14.9 0.7 1.2 1 0 0 1 1 1 0 Cgr1 family TAF1D PF15333.1 CCD27026.1 - 0.11 12.2 2.4 0.14 11.9 1.6 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D Phosphoprotein PF00922.12 CCD27026.1 - 1.8 7.7 5.7 2.2 7.4 4.0 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Securin PF04856.8 CCD27027.1 - 3.9e-16 59.4 22.3 2.3e-15 56.9 15.4 2.1 1 1 0 1 1 1 1 Securin sister-chromatid separation inhibitor Aminotran_1_2 PF00155.16 CCD27028.1 - 9.1e-36 123.5 0.0 1.4e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCD27028.1 - 0.0017 17.5 0.0 0.004 16.3 0.0 1.5 2 0 0 2 2 2 1 Beta-eliminating lyase SRP1_TIP1 PF00660.12 CCD27029.1 - 1.8e-32 111.2 0.2 2.4e-32 110.8 0.1 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family Gaa1 PF04114.9 CCD27031.1 - 1.4e-117 393.4 15.6 2.5e-112 376.1 3.3 2.1 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component FGGY_C PF02782.11 CCD27032.1 - 2.6e-51 174.0 0.0 3.8e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CCD27032.1 - 1.4e-21 76.9 0.2 4.8e-21 75.1 0.2 2.0 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.16 CCD27032.1 - 0.0037 16.6 0.1 0.012 14.9 0.0 1.7 2 0 0 2 2 2 1 Hexokinase UPF0075 PF03702.9 CCD27032.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) TRAPPC-Trs85 PF12739.2 CCD27033.1 - 2.1e-92 309.9 0.7 2.8e-92 309.5 0.5 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit EMP70 PF02990.11 CCD27034.1 - 1.2e-182 608.0 10.2 1.6e-182 607.5 7.0 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Actin PF00022.14 CCD27036.1 - 5e-07 28.4 0.0 4.9e-06 25.2 0.0 2.0 1 1 0 2 2 2 1 Actin Mor PF08765.6 CCD27036.1 - 0.13 12.0 0.0 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 Mor transcription activator family LRR_6 PF13516.1 CCD27036.1 - 0.26 11.4 2.2 9.4 6.6 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Serinc PF03348.10 CCD27037.1 - 1.1e-154 515.3 14.5 1.3e-154 515.0 10.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) PH_4 PF15404.1 CCD27038.1 - 1.3e-76 256.2 0.0 3e-76 255.0 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain Spo7_2_N PF15407.1 CCD27038.1 - 1.3e-24 85.3 2.8 2.6e-24 84.4 0.1 2.9 2 1 1 3 3 3 1 Sporulation protein family 7 Ste5_C PF12194.3 CCD27039.1 - 1.1e-74 250.2 4.1 2.2e-74 249.2 2.8 1.5 1 0 0 1 1 1 1 Protein kinase Fus3-binding zf-RING_2 PF13639.1 CCD27039.1 - 0.0012 18.6 3.3 0.0027 17.4 2.3 1.7 1 0 0 1 1 1 1 Ring finger domain PH_10 PF15411.1 CCD27039.1 - 0.0049 17.0 0.0 0.015 15.4 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Peptidase_M24 PF00557.19 CCD27040.1 - 1.2e-07 31.5 0.0 3.6e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Metallopeptidase family M24 COPI_assoc PF08507.5 CCD27041.1 - 3e-31 107.9 4.1 3.5e-31 107.7 2.8 1.0 1 0 0 1 1 1 1 COPI associated protein 14-3-3 PF00244.15 CCD27042.1 - 4e-115 382.8 5.9 4.6e-115 382.6 4.1 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF885 PF05960.6 CCD27042.1 - 0.017 14.3 0.7 0.027 13.6 0.3 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) DUF4085 PF13315.1 CCD27042.1 - 0.17 11.2 2.2 0.096 12.0 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4085) SPACA7 PF15307.1 CCD27042.1 - 0.62 10.2 4.2 17 5.6 0.2 2.8 2 1 0 2 2 2 0 Sperm acrosome-associated protein 7 Glutaredoxin PF00462.19 CCD27043.1 - 1.5e-18 66.5 0.0 5e-17 61.6 0.0 2.7 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 CCD27043.1 - 4.1e-14 52.1 0.0 9.7e-14 50.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CCD27043.1 - 1.6e-05 24.9 0.1 0.0045 17.0 0.0 2.7 1 1 1 2 2 2 2 Thioredoxin-like P22_CoatProtein PF11651.3 CCD27043.1 - 0.003 16.2 0.2 0.0039 15.8 0.1 1.1 1 0 0 1 1 1 1 P22 coat protein - gene protein 5 Thioredoxin_7 PF13899.1 CCD27043.1 - 0.0063 16.5 0.0 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like AAA_23 PF13476.1 CCD27043.1 - 0.039 14.2 2.5 0.053 13.8 1.7 1.2 1 0 0 1 1 1 0 AAA domain ArsC PF03960.10 CCD27043.1 - 0.043 13.8 0.0 0.26 11.3 0.0 2.2 2 1 0 2 2 2 0 ArsC family Ribosomal_60s PF00428.14 CCD27043.1 - 0.044 14.1 2.0 0.083 13.2 1.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein DUF3276 PF11680.3 CCD27043.1 - 0.15 11.8 1.8 0.33 10.7 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3276) MutS_V PF00488.16 CCD27044.1 - 2.7e-77 259.3 0.0 4.3e-77 258.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCD27044.1 - 3.8e-42 144.3 0.5 3.8e-42 144.3 0.3 1.7 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 CCD27044.1 - 7e-32 109.8 0.0 3.5e-31 107.5 0.0 2.2 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 CCD27044.1 - 3.7e-16 59.0 0.6 7.9e-16 58.0 0.0 1.9 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 CCD27044.1 - 1e-12 48.2 0.0 4e-12 46.3 0.0 2.0 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 CCD27044.1 - 0.044 13.3 0.0 0.16 11.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hydrolase_like2 PF13246.1 CCD27045.1 - 4.6e-14 52.1 0.1 1.2e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 CCD27045.1 - 4.8e-14 51.9 1.0 7.9e-14 51.2 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 CCD27045.1 - 4.7e-13 49.7 0.2 1.2e-12 48.4 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCD27045.1 - 6.3e-10 39.8 0.2 3.4e-08 34.1 0.2 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCD27045.1 - 0.0016 18.1 0.2 0.0039 16.8 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UQ_con PF00179.21 CCD27046.1 - 4.9e-48 162.1 0.0 5.6e-48 161.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCD27046.1 - 0.0023 17.6 0.0 0.003 17.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CCD27046.1 - 0.012 15.2 0.1 0.022 14.4 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 CCD27046.1 - 0.015 15.1 0.1 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 RWD domain SNF2_N PF00176.18 CCD27047.1 - 6.9e-76 254.8 0.1 1.8e-75 253.5 0.1 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF4208 PF13907.1 CCD27047.1 - 3.6e-27 94.5 2.6 3.6e-27 94.5 1.8 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4208) Chromo PF00385.19 CCD27047.1 - 6.4e-21 73.7 3.1 3.1e-13 49.1 0.1 3.4 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CCD27047.1 - 1.7e-16 59.8 0.1 2.4e-15 56.1 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 CCD27047.1 - 0.0016 18.4 0.0 0.0058 16.6 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain DNA_ligase_A_N PF04675.9 CCD27047.1 - 0.0031 17.3 0.6 0.0087 15.8 0.4 1.7 1 0 0 1 1 1 1 DNA ligase N terminus KOW PF00467.24 CCD27048.1 - 0.00031 20.3 0.4 0.00031 20.3 0.3 1.9 2 1 0 2 2 2 1 KOW motif Glyco_hydro_72 PF03198.9 CCD27049.1 - 7.7e-140 465.3 2.8 9.9e-140 464.9 2.0 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CCD27049.1 - 8e-15 55.0 0.2 1.6e-14 54.1 0.1 1.5 1 0 0 1 1 1 1 X8 domain P22_Tail-4 PF11650.3 CCD27049.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 P22 tail accessory factor Cellulase PF00150.13 CCD27049.1 - 0.021 14.0 0.1 0.082 12.0 0.1 1.9 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Glucan_synthase PF02364.10 CCD27050.1 - 0 1457.9 0.0 0 1457.5 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCD27050.1 - 1e-39 135.0 0.2 2.9e-39 133.6 0.1 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 LRS4 PF10422.4 CCD27051.1 - 9 5.5 9.8 0.35 10.1 0.1 2.2 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Ribosomal_S25 PF03297.10 CCD27052.1 - 4.8e-44 148.7 5.7 5.3e-44 148.5 3.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 CCD27052.1 - 0.00028 20.5 0.1 0.00043 19.9 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain HTH_CodY PF08222.6 CCD27052.1 - 0.03 13.6 0.1 0.046 13.0 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain RPA_C PF08784.6 CCD27052.1 - 0.058 13.8 0.0 0.078 13.3 0.0 1.1 1 0 0 1 1 1 0 Replication protein A C terminal HTH_DeoR PF08220.7 CCD27052.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain TAF4 PF05236.9 CCD27052.1 - 1.1 8.4 5.4 1.3 8.2 3.7 1.3 1 1 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Ran_BP1 PF00638.13 CCD27053.1 - 1.6e-37 128.2 0.1 4.9e-37 126.6 0.1 1.9 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 CCD27053.1 - 3.6e-12 46.4 0.2 3.6e-12 46.4 0.1 4.6 6 0 0 6 6 6 1 NUP50 (Nucleoporin 50 kDa) MA3 PF02847.12 CCD27054.1 - 1e-25 89.5 0.1 7.2e-25 86.8 0.0 2.6 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 CCD27054.1 - 2.4e-22 79.3 10.7 2.9e-22 79.1 4.0 2.7 2 1 0 2 2 2 1 MIF4G domain WH2 PF02205.15 CCD27055.1 - 8.5e-14 50.6 1.0 6.9e-11 41.3 0.2 2.6 2 0 0 2 2 2 2 WH2 motif BRCT PF00533.21 CCD27056.1 - 6.9e-11 42.1 0.0 1.5e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 CCD27056.1 - 0.0041 17.2 0.0 0.019 15.0 0.0 2.1 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 CCD27056.1 - 0.027 14.2 0.1 0.027 14.2 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3006) PTCB-BRCT PF12738.2 CCD27056.1 - 0.029 14.2 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 twin BRCT domain Mid2 PF04478.7 CCD27057.1 - 3.2e-58 195.5 2.9 3.2e-58 195.5 2.0 2.8 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 CCD27057.1 - 0.0014 17.9 0.4 0.0081 15.4 0.3 2.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF912 PF06024.7 CCD27057.1 - 0.01 15.8 0.2 0.032 14.2 0.1 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4448 PF14610.1 CCD27057.1 - 0.038 13.4 0.1 0.075 12.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF605 PF04652.11 CCD27057.1 - 0.06 12.7 9.6 0.092 12.1 6.6 1.3 1 0 0 1 1 1 0 Vta1 like MF_alpha_N PF05436.6 CCD27058.1 - 3.7e-27 93.8 0.5 4.6e-27 93.5 0.3 1.1 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus MF_alpha PF04648.7 CCD27058.1 - 3.5e-15 55.1 20.9 6.3e-05 22.9 2.0 3.2 3 0 0 3 3 3 3 Yeast mating factor alpha hormone DUF749 PF05370.6 CCD27058.1 - 0.14 12.1 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF749) CTP_transf_2 PF01467.21 CCD27060.1 - 9.9e-36 123.1 0.3 3e-35 121.6 0.0 1.9 2 0 0 2 2 2 1 Cytidylyltransferase HABP4_PAI-RBP1 PF04774.10 CCD27061.1 - 1.2e-05 25.7 1.4 1.6e-05 25.3 1.0 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family RE_LlaJI PF09563.5 CCD27061.1 - 0.007 15.0 0.0 0.0082 14.8 0.0 1.1 1 0 0 1 1 1 1 LlaJI restriction endonuclease DUF4112 PF13430.1 CCD27062.1 - 8e-30 102.8 0.2 1.1e-29 102.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) DUF2701 PF10857.3 CCD27062.1 - 0.3 10.8 1.1 6.8 6.5 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2701) Pex24p PF06398.6 CCD27063.1 - 1.2e-83 280.9 13.1 2.1e-83 280.1 9.1 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Zip PF02535.17 CCD27063.1 - 0.04 12.9 0.0 0.04 12.9 0.0 2.1 3 0 0 3 3 3 0 ZIP Zinc transporter zf-C3HC4_2 PF13923.1 CCD27064.1 - 3e-10 39.9 10.6 5.7e-10 39.0 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 CCD27064.1 - 8.2e-10 38.1 3.0 1.6e-09 37.2 2.0 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 CCD27064.1 - 7.9e-09 35.0 7.1 1.3e-08 34.3 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCD27064.1 - 1.4e-08 34.3 11.1 2.6e-08 33.4 7.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCD27064.1 - 4.4e-07 29.6 7.1 8e-07 28.7 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCD27064.1 - 2.6e-06 26.9 11.2 5e-06 26.0 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCD27064.1 - 3e-05 23.7 9.3 7.2e-05 22.5 6.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCD27064.1 - 8.9e-05 22.1 2.0 0.00037 20.1 1.3 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 CCD27064.1 - 0.0019 17.9 2.3 0.0045 16.7 1.6 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 CCD27064.1 - 0.012 15.6 6.0 0.037 14.1 4.2 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 CCD27064.1 - 0.03 13.8 4.7 0.068 12.7 3.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 CCD27064.1 - 0.2 11.2 7.1 0.78 9.3 2.8 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 CCD27064.1 - 0.53 9.8 6.2 1.1 8.8 4.3 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Vmethyltransf_C PF08456.5 CCD27064.1 - 0.61 9.4 0.1 0.61 9.4 0.0 2.2 2 1 0 2 2 2 0 Viral methyltransferase C-terminal zf-P11 PF03854.9 CCD27064.1 - 1.3 8.5 7.5 2.8 7.4 5.2 1.4 1 0 0 1 1 1 0 P-11 zinc finger Mus7 PF09462.5 CCD27065.1 - 7.1e-32 111.0 16.9 1.8e-18 66.7 6.1 2.4 1 1 0 2 2 2 2 Mus7/MMS22 family SOBP PF15279.1 CCD27065.1 - 0.55 10.5 1.5 1.1 9.5 1.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein AIP3 PF03915.8 CCD27066.1 - 6.2e-147 489.9 16.8 6.2e-147 489.9 11.7 2.5 2 1 0 2 2 2 1 Actin interacting protein 3 Telomerase_RBD PF12009.3 CCD27067.1 - 3.1e-26 91.9 6.9 3.1e-26 91.9 2.0 2.9 2 0 0 2 2 2 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CCD27067.1 - 1.4e-07 31.1 4.7 4.6e-07 29.3 0.9 2.9 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) SNF5 PF04855.7 CCD27068.1 - 9.9e-54 182.3 10.5 2e-52 178.1 4.0 2.9 2 1 0 2 2 2 1 SNF5 / SMARCB1 / INI1 Ig_3 PF13927.1 CCD27068.1 - 0.024 15.1 0.2 0.18 12.3 0.0 2.5 1 1 1 2 2 2 0 Immunoglobulin domain AmoC PF04896.7 CCD27068.1 - 0.12 11.3 0.1 0.19 10.7 0.1 1.2 1 0 0 1 1 1 0 Ammonia monooxygenase/methane monooxygenase, subunit C EF1_GNE PF00736.14 CCD27069.1 - 4.3e-33 112.8 2.2 7.4e-33 112.1 1.5 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CCD27069.1 - 1.1e-11 44.6 4.4 1.1e-11 44.6 3.1 3.1 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region DNA_pol3_a_NII PF11490.3 CCD27069.1 - 0.25 10.9 0.2 0.25 10.9 0.1 2.1 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Ribophorin_II PF05817.9 CCD27070.1 - 0.96 7.5 4.3 1.3 7.1 3.0 1.1 1 0 0 1 1 1 0 Oligosaccharyltransferase subunit Ribophorin II Vps8 PF12816.2 CCD27071.1 - 1.3e-48 164.9 1.2 1.3e-48 164.9 0.8 2.3 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 zf-RING_2 PF13639.1 CCD27071.1 - 0.026 14.3 1.8 0.05 13.4 0.2 2.2 2 0 0 2 2 2 0 Ring finger domain zf-C3HC4_2 PF13923.1 CCD27071.1 - 0.036 14.0 0.1 0.13 12.2 0.1 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCD27071.1 - 0.053 13.6 6.7 0.027 14.5 1.7 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger zf-C3HC4 PF00097.20 CCD27071.1 - 0.11 12.1 0.1 0.39 10.4 0.1 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCD27071.1 - 0.64 9.7 2.5 2.3 7.9 1.8 1.9 1 1 0 1 1 1 0 zinc-RING finger domain B-block_TFIIIC PF04182.7 CCD27072.1 - 3.5e-18 65.1 0.1 1.3e-17 63.4 0.1 2.1 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC PCI PF01399.22 CCD27072.1 - 0.034 14.4 0.6 0.54 10.6 0.1 3.1 3 0 0 3 3 3 0 PCI domain BSMAP PF12280.3 CCD27072.1 - 0.079 12.8 2.8 0.11 12.3 0.7 2.1 2 0 0 2 2 2 0 Brain specific membrane anchored protein DUF1669 PF07894.7 CCD27074.1 - 0.061 12.5 0.3 0.13 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) EMP24_GP25L PF01105.19 CCD27075.1 - 6.4e-53 179.1 0.2 7.8e-53 178.9 0.1 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD WD40 PF00400.27 CCD27076.1 - 3e-18 64.9 6.4 7.1e-10 38.3 0.8 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.6 CCD27076.1 - 0.0002 21.1 0.7 0.045 13.4 0.0 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 CCD27076.1 - 0.0034 15.7 0.0 0.015 13.6 0.0 1.9 2 1 0 2 2 2 1 Cytochrome D1 heme domain DUF1623 PF07785.6 CCD27076.1 - 0.038 13.9 1.5 0.054 13.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1623) WD40 PF00400.27 CCD27077.1 - 1.9e-28 97.2 6.0 1.4e-05 24.7 0.6 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CCD27077.1 - 1.8e-06 27.7 0.3 0.002 17.8 0.2 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 CCD27077.1 - 0.0041 16.8 0.1 1.3 8.7 0.1 2.4 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Rep_fac-A_C PF08646.5 CCD27078.1 - 3.6e-58 195.4 8.9 3.2e-55 185.8 1.8 3.4 4 0 0 4 4 4 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CCD27078.1 - 8.5e-19 67.1 0.2 1.1e-08 34.7 0.0 4.5 4 0 0 4 4 4 4 OB-fold nucleic acid binding domain tRNA_int_endo PF01974.12 CCD27079.1 - 8e-14 51.2 0.0 1.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Transaldolase PF00923.14 CCD27080.1 - 4.2e-100 334.5 1.1 4.9e-100 334.3 0.8 1.0 1 0 0 1 1 1 1 Transaldolase Gly_rich_SFCGS PF14272.1 CCD27080.1 - 0.093 12.6 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycine-rich SFCGS IlvC PF01450.14 CCD27081.1 - 6.8e-48 162.2 0.0 1.3e-47 161.3 0.0 1.5 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 CCD27081.1 - 1e-45 155.0 0.0 1.5e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Adeno_Penton_B PF01686.12 CCD27081.1 - 0.042 12.0 0.0 0.057 11.6 0.0 1.2 1 0 0 1 1 1 0 Adenovirus penton base protein NAD_binding_2 PF03446.10 CCD27081.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Cir_Bir_Yir PF06022.6 CCD27082.1 - 0.14 11.3 0.5 0.19 10.9 0.4 1.1 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir eIF2A PF08662.6 CCD27083.1 - 2e-75 252.7 0.1 9.1e-75 250.6 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CCD27083.1 - 0.00083 19.1 0.7 6.3 6.8 0.1 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat Hyphal_reg_CWP PF11765.3 CCD27084.1 - 3.3e-05 22.8 7.5 0.0012 17.6 2.9 2.4 2 0 0 2 2 2 2 Hyphally regulated cell wall protein N-terminal Filament_head PF04732.9 CCD27084.1 - 0.21 12.3 0.0 0.21 12.3 0.0 3.5 2 1 0 2 2 2 0 Intermediate filament head (DNA binding) region AA_permease_2 PF13520.1 CCD27085.1 - 2.7e-85 286.4 48.2 3.3e-85 286.2 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCD27085.1 - 7.7e-22 77.2 44.7 1e-21 76.8 31.0 1.1 1 0 0 1 1 1 1 Amino acid permease BAH PF01426.13 CCD27086.1 - 2.3e-22 78.9 0.1 4.4e-22 78.0 0.1 1.5 1 0 0 1 1 1 1 BAH domain Bromodomain PF00439.20 CCD27086.1 - 7.9e-16 57.7 5.2 1.8e-09 37.3 0.2 3.2 3 0 0 3 3 3 2 Bromodomain Lyase_1 PF00206.15 CCD27087.1 - 1.6e-22 80.1 0.0 2.7e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 CCD27087.1 - 4.3e-16 58.6 0.0 1.8e-15 56.7 0.0 2.1 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus AsiA PF09010.5 CCD27087.1 - 0.037 13.9 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Anti-Sigma Factor A DUF1331 PF07048.6 CCD27087.1 - 0.074 12.5 1.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1331) Metallophos PF00149.23 CCD27089.1 - 2.9e-06 26.8 0.1 7e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase PF00069.20 CCD27091.1 - 1.4e-68 230.8 1.1 1.2e-66 224.5 0.8 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD27091.1 - 7.1e-48 162.9 0.7 3.5e-46 157.3 0.5 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 CCD27091.1 - 3.4e-32 110.4 0.4 9.2e-32 109.1 0.3 1.8 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 CCD27091.1 - 3.7e-12 45.9 0.0 1.7e-11 43.7 0.0 2.3 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCD27091.1 - 1.6e-08 34.5 0.1 1.6e-08 34.5 0.0 2.3 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 CCD27091.1 - 1e-07 31.2 0.0 2.6e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Kinase-like DUF2570 PF10828.3 CCD27091.1 - 0.11 12.0 7.1 0.032 13.8 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) PIN_4 PF13638.1 CCD27092.1 - 0.0064 16.5 0.0 0.016 15.2 0.0 1.7 1 1 0 1 1 1 1 PIN domain Glutaredoxin PF00462.19 CCD27093.1 - 9.3e-07 28.7 0.0 2e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Glutaredoxin CUB PF00431.15 CCD27093.1 - 0.0094 16.0 0.1 0.01 15.9 0.1 1.2 1 0 0 1 1 1 1 CUB domain Thioredoxin PF00085.15 CCD27093.1 - 0.06 13.0 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.1 CCD27093.1 - 0.092 12.5 0.0 0.17 11.7 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin domain Thioredoxin_4 PF13462.1 CCD27093.1 - 0.094 12.7 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_9 PF14595.1 CCD27093.1 - 0.11 12.0 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin HSP70 PF00012.15 CCD27094.1 - 1.4e-209 697.0 6.5 1.7e-209 696.7 4.5 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCD27094.1 - 3e-18 65.5 0.5 1.2e-15 56.9 0.1 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CCD27094.1 - 0.0012 18.5 0.0 0.0024 17.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 CCD27094.1 - 0.023 14.0 0.0 0.5 9.6 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 CCD27094.1 - 0.03 14.1 2.6 6.2 6.6 0.2 3.6 2 1 0 2 2 2 0 Cell division protein FtsA P21-Arc PF04062.9 CCD27095.1 - 1e-81 272.8 0.2 1.1e-81 272.7 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit SPOB_a PF14689.1 CCD27095.1 - 0.098 12.2 0.1 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain ELO PF01151.13 CCD27096.1 - 3.7e-57 193.4 30.9 4.8e-57 193.1 21.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family OAD_gamma PF04277.8 CCD27096.1 - 0.046 14.0 0.3 0.13 12.6 0.2 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain MSC PF09402.5 CCD27096.1 - 5.4 5.6 6.9 1.4 7.5 0.5 2.2 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain zf-BED PF02892.10 CCD27097.1 - 1.3e-05 24.8 1.8 3.1e-05 23.6 1.2 1.6 1 0 0 1 1 1 1 BED zinc finger Ribosomal_S27e PF01667.12 CCD27097.1 - 0.0084 15.6 0.2 0.016 14.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S27 zf-C2H2_4 PF13894.1 CCD27098.1 - 2.2e-08 33.8 17.2 0.0053 17.0 0.7 5.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCD27098.1 - 4.4e-08 32.7 6.1 0.00064 19.5 0.1 4.1 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCD27098.1 - 1.3e-05 25.2 23.8 0.0023 18.1 1.4 5.1 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-Di19 PF05605.7 CCD27098.1 - 0.00036 20.5 4.9 0.005 16.9 1.2 3.4 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 CCD27098.1 - 0.0036 17.5 28.4 0.0084 16.3 1.5 5.7 4 1 1 5 5 5 2 Zinc-finger double domain zf-C2HC_2 PF13913.1 CCD27098.1 - 0.01 15.4 8.4 0.92 9.2 0.8 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 CCD27098.1 - 0.024 14.7 10.5 0.46 10.6 0.1 4.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding DZR PF12773.2 CCD27098.1 - 0.038 13.8 2.8 0.69 9.7 0.5 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_3 PF14369.1 CCD27098.1 - 0.1 12.5 2.6 11 6.0 0.1 3.6 3 0 0 3 3 3 0 zinc-finger Rad50_zn_hook PF04423.9 CCD27098.1 - 0.16 11.4 7.4 0.24 10.9 0.1 2.8 2 1 1 3 3 3 0 Rad50 zinc hook motif FYVE PF01363.16 CCD27098.1 - 0.43 10.4 8.5 1.6 8.6 1.7 3.1 2 1 1 3 3 3 0 FYVE zinc finger zf-met PF12874.2 CCD27098.1 - 0.51 10.6 8.9 3.1 8.1 0.2 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zinc_ribbon_4 PF13717.1 CCD27098.1 - 1 9.1 7.2 3.6 7.3 0.4 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_5 PF14634.1 CCD27098.1 - 1 9.1 4.8 23 4.7 0.1 3.1 3 0 0 3 3 3 0 zinc-RING finger domain zinc_ribbon_5 PF13719.1 CCD27098.1 - 1.6 8.3 8.2 3.8 7.1 0.4 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-ISL3 PF14690.1 CCD27098.1 - 2.9 8.0 9.5 18 5.4 0.9 4.0 4 0 0 4 4 4 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 KRE9 PF05390.6 CCD27100.1 - 4.2e-27 94.6 1.7 1.3e-26 93.0 1.2 1.8 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CCD27100.1 - 8.9e-07 29.3 0.4 8.9e-07 29.3 0.3 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Neurexophilin PF06312.7 CCD27100.1 - 0.0079 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Neurexophilin FBPase PF00316.15 CCD27102.1 - 4.2e-127 423.4 0.0 5.1e-127 423.1 0.0 1.1 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase NdhM PF10664.4 CCD27102.1 - 0.073 12.9 0.0 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 Cyanobacterial and plastid NDH-1 subunit M DUF605 PF04652.11 CCD27104.1 - 5.9e-43 147.7 18.6 1.6e-42 146.3 12.9 1.6 1 1 0 1 1 1 1 Vta1 like Ku_N PF03731.10 CCD27104.1 - 0.00031 20.2 5.7 0.00031 20.2 3.9 2.8 3 1 0 3 3 3 1 Ku70/Ku80 N-terminal alpha/beta domain Peptidase_S41 PF03572.13 CCD27104.1 - 0.092 12.1 3.3 0.12 11.8 0.0 2.5 3 0 0 3 3 3 0 Peptidase family S41 SecY PF00344.15 CCD27105.1 - 4.4e-88 295.5 15.7 5.7e-88 295.1 10.9 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CCD27105.1 - 1.3e-18 66.1 0.2 6.7e-18 63.8 0.1 2.4 1 0 0 1 1 1 1 Plug domain of Sec61p NTP_transferase PF00483.18 CCD27106.1 - 8.9e-49 166.0 0.0 1.8e-48 165.0 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CCD27106.1 - 7.4e-14 50.5 13.8 7.1e-08 31.6 1.2 3.7 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CCD27106.1 - 3.5e-10 40.1 0.0 4.8e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CCD27106.1 - 0.00022 20.6 6.6 0.00072 19.0 0.9 3.1 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 CCD27106.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Cytidylyltransferase IspD PF01128.14 CCD27106.1 - 0.1 12.1 0.0 0.36 10.2 0.0 1.9 2 0 0 2 2 2 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CRAL_TRIO PF00650.15 CCD27107.1 - 8.6e-36 122.8 0.0 1.5e-35 122.0 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCD27107.1 - 9.6e-10 38.4 0.1 3.8e-09 36.5 0.1 2.2 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCD27107.1 - 1.7e-08 34.4 0.3 3.9e-08 33.3 0.2 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain SR-25 PF10500.4 CCD27107.1 - 0.42 10.0 7.5 0.68 9.3 5.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein tRNA-synt_1 PF00133.17 CCD27109.1 - 2.3e-50 171.2 0.2 1.1e-18 66.6 0.2 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 CCD27109.1 - 4.6e-35 120.6 0.0 8e-35 119.8 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 CCD27109.1 - 8.3e-27 93.8 0.7 4.3e-20 71.7 0.1 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CCD27109.1 - 1.3e-07 31.5 0.2 2.7e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 CCD27109.1 - 0.00013 20.9 0.0 0.00028 19.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (R) Ribosomal_S27e PF01667.12 CCD27109.1 - 0.22 11.0 0.7 1.2 8.7 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein S27 SMC_N PF02463.14 CCD27110.1 - 8e-26 90.6 7.2 1.2e-24 86.7 5.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCD27110.1 - 3.1e-09 37.4 35.0 3.1e-09 37.4 24.2 5.7 2 2 0 2 2 1 1 AAA domain AAA_13 PF13166.1 CCD27110.1 - 3e-05 22.7 80.8 0.0072 14.8 13.7 4.7 4 1 0 5 5 5 4 AAA domain AAA_29 PF13555.1 CCD27110.1 - 0.0011 18.3 0.0 0.0032 16.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 CCD27110.1 - 0.0037 16.4 7.2 0.0037 16.4 5.0 6.1 2 2 3 5 5 4 3 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 CCD27110.1 - 0.0062 15.7 12.8 0.057 12.5 0.1 4.0 3 2 0 4 4 4 2 Reovirus sigma C capsid protein AAA_21 PF13304.1 CCD27110.1 - 0.0077 16.2 0.3 0.0077 16.2 0.2 4.4 3 1 1 4 4 4 2 AAA domain SbcCD_C PF13558.1 CCD27110.1 - 0.013 15.3 0.0 0.045 13.6 0.0 1.9 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_tran PF00005.22 CCD27110.1 - 0.15 12.3 0.0 0.15 12.3 0.0 5.4 3 2 0 3 3 2 0 ABC transporter FlaC_arch PF05377.6 CCD27110.1 - 0.64 9.9 27.3 0.41 10.5 2.2 7.7 5 2 1 6 6 6 0 Flagella accessory protein C (FlaC) Hemerythrin PF01814.18 CCD27110.1 - 5 7.2 17.2 0.49 10.5 5.4 3.2 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain AAA_16 PF13191.1 CCD27110.1 - 8.3 6.3 9.9 3.1 7.7 0.0 4.0 4 1 0 4 4 4 0 AAA ATPase domain IKI3 PF04762.7 CCD27111.1 - 0 1139.1 6.6 0 1139.1 4.6 1.4 2 0 0 2 2 2 1 IKI3 family Vac14_Fig4_bd PF11916.3 CCD27113.1 - 1.5e-69 232.8 5.2 1.5e-69 232.8 3.6 2.4 3 0 0 3 3 3 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CCD27113.1 - 6.8e-48 161.0 0.1 2.4e-38 130.4 0.0 4.6 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CCD27113.1 - 1.2e-09 37.4 7.5 0.00024 20.9 0.0 7.5 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.1 CCD27113.1 - 1.9e-07 31.2 0.0 0.033 14.4 0.0 5.2 4 1 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 CCD27113.1 - 2.7e-07 30.8 0.4 0.39 11.2 0.0 6.1 5 1 1 6 6 6 2 HEAT-like repeat CLASP_N PF12348.3 CCD27113.1 - 7.7e-07 28.6 0.1 0.75 9.1 0.3 4.7 4 1 0 4 4 4 3 CLASP N terminal Ipi1_N PF12333.3 CCD27113.1 - 0.014 15.3 0.8 2.7 8.0 0.0 3.9 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 CCD27113.1 - 0.014 15.2 12.7 0.19 11.5 0.0 4.4 5 0 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Secretin_N_2 PF07655.8 CCD27113.1 - 0.1 13.0 7.0 0.23 11.8 4.9 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Arm PF00514.18 CCD27113.1 - 0.52 10.2 5.4 3.4 7.6 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat zf-C2H2_2 PF12756.2 CCD27114.1 - 1.1e-28 99.3 7.1 1.9e-27 95.3 0.8 2.6 2 1 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Propeptide_C1 PF08127.8 CCD27114.1 - 0.23 11.1 1.0 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 Peptidase family C1 propeptide zf-C2H2_jaz PF12171.3 CCD27114.1 - 0.65 10.2 5.9 0.39 10.9 0.6 3.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF663 PF04950.7 CCD27115.1 - 7.7e-105 350.1 0.1 1.7e-104 348.9 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CCD27115.1 - 4.4e-23 80.6 0.0 1e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Peptidase_M16 PF00675.15 CCD27116.1 - 2.3e-37 128.0 0.0 4.2e-36 123.9 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCD27116.1 - 1.4e-30 106.3 6.4 3.8e-19 69.0 0.0 3.0 4 0 0 4 4 4 2 Peptidase M16 inactive domain Slx4 PF09494.5 CCD27117.1 - 0.039 13.7 0.0 0.059 13.1 0.0 1.3 1 0 0 1 1 1 0 Slx4 endonuclease UBA_3 PF09288.5 CCD27117.1 - 0.05 13.2 0.1 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain CFEM PF05730.6 CCD27118.1 - 2.1e-07 30.6 14.9 6.4e-07 29.0 10.3 1.9 1 0 0 1 1 1 1 CFEM domain Pol_alpha_B_N PF08418.5 CCD27118.1 - 0.27 10.7 21.5 0.46 9.9 14.9 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal ATG16 PF08614.6 CCD27118.1 - 0.43 10.3 6.0 0.67 9.7 4.2 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) CytochromB561_N PF09786.4 CCD27118.1 - 0.59 8.5 25.9 0.63 8.4 18.0 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF572 PF04502.8 CCD27118.1 - 4.6 6.3 18.5 5.6 6.0 12.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Arrestin_N PF00339.24 CCD27119.1 - 0.0002 21.2 0.0 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ATP-synt_10 PF05176.9 CCD27120.1 - 8.5e-78 261.1 1.1 1e-77 260.8 0.8 1.0 1 0 0 1 1 1 1 ATP10 protein zf-RING_5 PF14634.1 CCD27121.1 - 3e-08 33.2 6.6 7.3e-08 32.0 4.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 CCD27121.1 - 0.086 12.6 1.9 0.19 11.5 1.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 CCD27121.1 - 0.12 11.8 7.6 0.33 10.4 5.3 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.1 CCD27121.1 - 0.57 10.2 7.3 1.6 8.8 5.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCD27121.1 - 0.86 9.4 6.7 2.3 8.1 4.6 1.8 1 0 0 1 1 1 0 Ring finger domain Med9 PF07544.8 CCD27121.1 - 6.6 6.5 15.7 3 7.6 0.2 4.3 4 1 1 5 5 5 0 RNA polymerase II transcription mediator complex subunit 9 COX7C PF02935.11 CCD27122.1 - 1.1e-21 76.3 3.9 1.3e-21 76.1 2.7 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Chromo_shadow PF01393.14 CCD27122.1 - 0.0011 18.7 0.2 0.15 11.9 0.0 2.2 2 0 0 2 2 2 2 Chromo shadow domain Sec1 PF00995.18 CCD27123.1 - 1.9e-67 228.2 8.7 2.5e-67 227.8 6.0 1.2 1 0 0 1 1 1 1 Sec1 family Dehydratase_SU PF02287.10 CCD27123.1 - 0.047 13.4 0.0 0.49 10.1 0.0 2.3 2 0 0 2 2 2 0 Dehydratase small subunit AAA PF00004.24 CCD27124.1 - 6.2e-90 298.2 0.0 9.9e-44 148.7 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCD27124.1 - 1.2e-12 47.3 0.0 2.1e-05 23.6 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCD27124.1 - 1.9e-12 47.5 0.1 5.4e-06 26.5 0.0 3.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CCD27124.1 - 5.5e-12 45.6 0.1 4e-05 23.3 0.0 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCD27124.1 - 4.1e-11 43.1 0.5 7.2e-05 22.9 0.0 4.4 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CCD27124.1 - 4.1e-09 36.4 0.0 0.00023 21.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 CCD27124.1 - 1.3e-07 31.7 0.0 0.011 15.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 CCD27124.1 - 5.4e-07 28.6 0.0 0.0046 15.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 C-terminus AAA_33 PF13671.1 CCD27124.1 - 8e-07 29.0 0.0 0.00048 20.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCD27124.1 - 4.1e-06 27.6 0.0 0.027 15.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CCD27124.1 - 1e-05 25.6 0.0 0.11 12.6 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.1 CCD27124.1 - 1.7e-05 24.3 6.6 0.27 10.6 0.1 4.3 2 2 2 4 4 4 2 AAA domain Mg_chelatase PF01078.16 CCD27124.1 - 2.3e-05 23.6 0.4 0.062 12.4 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.13 CCD27124.1 - 2.4e-05 24.0 0.0 0.0038 16.9 0.0 2.7 2 2 0 2 2 2 1 Bacterial dnaA protein AAA_28 PF13521.1 CCD27124.1 - 4.1e-05 23.6 0.0 0.11 12.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 CCD27124.1 - 5.7e-05 22.8 0.1 0.012 15.2 0.0 3.6 3 1 1 4 4 4 1 NACHT domain Sigma54_activ_2 PF14532.1 CCD27124.1 - 0.00022 21.2 0.0 0.085 12.9 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain CDC48_N PF02359.13 CCD27124.1 - 0.00027 20.8 0.2 0.00085 19.2 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain Zeta_toxin PF06414.7 CCD27124.1 - 0.00029 20.0 0.0 0.25 10.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 CCD27124.1 - 0.00029 20.5 7.8 0.0016 18.1 0.1 3.6 4 1 0 4 4 2 1 Part of AAA domain IstB_IS21 PF01695.12 CCD27124.1 - 0.00045 19.6 0.0 0.57 9.5 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.10 CCD27124.1 - 0.00063 18.5 0.0 0.037 12.7 0.0 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 CCD27124.1 - 0.0014 18.3 0.0 6.9 6.2 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase AAA_3 PF07726.6 CCD27124.1 - 0.0017 17.9 0.0 1.6 8.3 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCD27124.1 - 0.0026 17.2 0.2 12 5.3 0.0 4.6 3 2 0 3 3 3 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 CCD27124.1 - 0.0077 15.7 0.0 0.051 13.0 0.0 2.1 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 CCD27124.1 - 0.011 15.3 0.0 0.62 9.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 CCD27124.1 - 0.011 14.8 0.4 9.1 5.3 0.0 3.2 2 1 1 3 3 3 0 KaiC ABC_tran PF00005.22 CCD27124.1 - 0.016 15.4 0.1 0.56 10.5 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 CCD27124.1 - 0.02 14.4 0.1 0.15 11.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 CCD27124.1 - 0.039 13.5 0.4 7.1 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.8 CCD27124.1 - 0.04 12.8 0.0 1.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AFG1_ATPase PF03969.11 CCD27124.1 - 0.041 12.6 0.0 0.12 11.1 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase NTPase_1 PF03266.10 CCD27124.1 - 0.058 13.1 0.6 1.1 8.9 0.0 3.1 2 2 2 4 4 4 0 NTPase AAA_18 PF13238.1 CCD27124.1 - 0.058 13.6 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CCD27124.1 - 0.087 12.3 0.0 0.43 10.0 0.0 2.0 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain UPF0079 PF02367.12 CCD27124.1 - 0.1 12.2 0.2 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DSHCT PF08148.7 CCD27125.1 - 7e-60 201.3 0.2 1.9e-59 199.9 0.1 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CCD27125.1 - 1.3e-22 80.0 0.1 4.3e-22 78.4 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 CCD27125.1 - 3.3e-07 29.7 0.2 7.4e-07 28.5 0.1 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 CCD27125.1 - 1.8e-06 27.7 0.0 6.2e-06 25.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HD_assoc PF13286.1 CCD27125.1 - 0.18 12.0 3.4 0.22 11.8 0.1 2.7 3 0 0 3 3 3 0 Phosphohydrolase-associated domain Bromodomain PF00439.20 CCD27126.1 - 1.4e-39 133.8 1.7 8.9e-19 67.1 0.0 2.7 2 0 0 2 2 2 2 Bromodomain Dus PF01207.12 CCD27127.1 - 4.4e-39 134.1 0.0 2.8e-29 101.9 0.0 2.3 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 CCD27127.1 - 0.00016 21.2 4.8 0.019 14.6 0.2 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RtcR PF06956.6 CCD27127.1 - 0.039 13.2 0.0 0.1 11.9 0.0 1.6 1 0 0 1 1 1 0 Regulator of RNA terminal phosphate cyclase zf-CCCH_2 PF14608.1 CCD27127.1 - 0.043 13.8 0.3 0.043 13.8 0.2 2.0 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Tom37_C PF11801.3 CCD27127.1 - 8 6.3 10.4 6.6 6.5 0.5 2.6 2 0 0 2 2 2 0 Tom37 C-terminal domain zf-C2H2_4 PF13894.1 CCD27128.1 - 2.3e-06 27.5 12.3 0.037 14.3 0.1 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCD27128.1 - 0.00068 19.8 13.2 0.03 14.6 0.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CCD27128.1 - 0.0013 18.9 18.1 0.055 13.8 0.8 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCD27128.1 - 0.0014 18.6 5.0 0.43 10.7 0.1 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCD27128.1 - 2 8.4 8.2 1.1 9.2 0.3 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3671 PF12420.3 CCD27129.1 - 0.048 13.6 1.3 2.8 7.9 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function Sigma_reg_N PF13800.1 CCD27129.1 - 5.4 7.1 8.5 6.6 6.8 1.5 3.0 3 0 0 3 3 3 0 Sigma factor regulator N-terminal Dus PF01207.12 CCD27130.1 - 1.8e-73 247.0 0.0 2.2e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) MOZART1 PF12554.3 CCD27130.1 - 0.078 12.4 0.2 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated DUF4050 PF13259.1 CCD27131.1 - 4.5e-24 84.6 5.3 5.5e-24 84.4 3.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) Luteo_coat PF00894.13 CCD27131.1 - 0.087 12.5 1.1 0.15 11.8 0.8 1.3 1 0 0 1 1 1 0 Luteovirus coat protein PTRF_SDPR PF15237.1 CCD27131.1 - 0.12 11.8 6.3 0.021 14.2 1.4 1.7 1 1 0 1 1 1 0 PTRF/SDPR family AbbA_antirepres PF14156.1 CCD27132.1 - 0.003 17.1 1.5 0.017 14.7 1.0 2.0 1 1 1 2 2 2 1 Antirepressor AbbA IlvC PF01450.14 CCD27132.1 - 0.074 12.9 0.1 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain GPAT_N PF14829.1 CCD27132.1 - 0.1 12.3 0.1 0.16 11.6 0.0 1.4 1 1 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal Utp21 PF04192.7 CCD27133.1 - 8.1e-80 267.3 0.9 1.2e-79 266.8 0.6 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CCD27133.1 - 2.5e-24 84.1 10.9 5.8e-10 38.6 0.5 8.6 9 0 0 9 9 9 4 WD domain, G-beta repeat PQQ_2 PF13360.1 CCD27133.1 - 2.8e-06 26.9 0.0 0.009 15.4 0.0 2.9 2 1 0 2 2 2 2 PQQ-like domain Nucleoporin_N PF08801.6 CCD27133.1 - 0.00019 20.3 0.3 0.2 10.3 0.0 3.5 2 1 1 3 3 3 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 CCD27133.1 - 0.00038 18.8 0.0 0.004 15.5 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain CPSF_A PF03178.10 CCD27133.1 - 0.001 18.2 0.2 0.18 10.8 0.0 3.3 3 0 0 3 3 3 1 CPSF A subunit region PQQ_3 PF13570.1 CCD27133.1 - 0.0031 17.7 0.6 0.15 12.3 0.0 3.8 5 0 0 5 5 5 1 PQQ-like domain Apc4_WD40 PF12894.2 CCD27133.1 - 0.014 14.8 0.1 14 5.3 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain LVIVD PF08309.6 CCD27133.1 - 0.025 13.5 0.1 4.1 6.4 0.0 2.4 2 0 0 2 2 2 0 LVIVD repeat His_Phos_2 PF00328.17 CCD27134.1 - 3.6e-131 437.6 0.5 5.2e-131 437.0 0.4 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CCD27134.1 - 1.3e-08 34.5 0.0 3.1e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CCD27134.1 - 0.0015 18.4 0.2 0.0069 16.2 0.1 2.2 1 1 0 1 1 1 1 ATP-grasp domain Ctr PF04145.10 CCD27135.1 - 4.1e-40 137.1 1.5 1.1e-39 135.7 1.0 1.7 1 1 0 1 1 1 1 Ctr copper transporter family Hid1 PF12722.2 CCD27136.1 - 2.3e-155 518.6 122.6 5.2e-133 444.6 51.6 2.9 1 1 1 2 2 2 2 High-temperature-induced dauer-formation protein WGG PF10273.4 CCD27137.1 - 1.7e-31 108.1 0.1 4.2e-31 106.8 0.1 1.7 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Recombinase PF07508.8 CCD27137.1 - 0.03 14.5 0.6 0.17 12.1 0.4 2.2 1 1 0 1 1 1 0 Recombinase Metallophos PF00149.23 CCD27138.1 - 4.1e-39 134.0 2.1 6.5e-39 133.4 1.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SEN1_N PF12726.2 CCD27140.1 - 7e-222 738.4 30.3 9.4e-222 738.0 21.0 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 CCD27140.1 - 3.5e-68 229.7 0.7 3.5e-68 229.7 0.5 3.4 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.1 CCD27140.1 - 2.1e-64 216.6 0.3 6.5e-64 214.9 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCD27140.1 - 4.1e-10 39.2 0.0 1.5e-09 37.4 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CCD27140.1 - 1.2e-08 34.7 0.0 1e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF1900 PF08954.6 CCD27141.1 - 8.8e-49 164.5 0.0 2e-48 163.3 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CCD27141.1 - 6.2e-31 105.8 0.4 1.2e-30 104.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CCD27141.1 - 1.1e-23 82.1 8.5 9.4e-08 31.6 0.0 4.6 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 CCD27141.1 - 7.3e-08 31.0 0.2 7.7e-05 21.0 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 CCD27141.1 - 0.0019 17.9 0.7 1.6 8.4 0.0 3.0 3 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A zf-C3HC4 PF00097.20 CCD27142.1 - 2.1e-07 30.4 3.1 6.2e-07 28.9 2.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD27142.1 - 9.2e-07 28.7 6.9 2e-06 27.7 4.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCD27142.1 - 9.4e-07 28.5 5.8 1.7e-06 27.7 4.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCD27142.1 - 3.6e-06 26.5 5.9 8.9e-06 25.3 4.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCD27142.1 - 4.9e-06 26.1 4.4 8.9e-06 25.2 3.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCD27142.1 - 1.4e-05 24.6 3.0 4.3e-05 23.1 2.1 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCD27142.1 - 0.0016 18.3 7.1 0.012 15.4 5.2 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING FYVE PF01363.16 CCD27142.1 - 0.099 12.5 2.3 0.28 11.1 1.6 1.8 1 0 0 1 1 1 0 FYVE zinc finger zf-Nse PF11789.3 CCD27142.1 - 0.23 11.0 5.1 0.64 9.5 3.5 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-MIZ PF02891.15 CCD27142.1 - 1.5 8.4 6.6 5.8 6.5 4.5 2.0 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger adh_short PF00106.20 CCD27143.1 - 1.2e-15 57.7 0.0 7.4e-15 55.2 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCD27143.1 - 0.011 15.3 0.1 0.23 11.0 0.0 2.1 1 1 0 1 1 1 0 KR domain UEV PF05743.8 CCD27143.1 - 0.013 15.2 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 UEV domain DUF1776 PF08643.5 CCD27143.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) CNH PF00780.17 CCD27144.1 - 2.5e-17 63.1 4.6 3.7e-17 62.6 2.1 2.2 2 1 0 2 2 2 1 CNH domain PH PF00169.24 CCD27144.1 - 3.5e-13 49.6 1.6 3.5e-13 49.6 1.1 3.7 3 2 0 3 3 3 1 PH domain PH_5 PF15405.1 CCD27144.1 - 2.1e-06 27.7 1.1 2.1e-06 27.7 0.8 4.1 3 1 0 4 4 4 1 Pleckstrin homology domain CHCH PF06747.8 CCD27145.1 - 2.7e-07 30.3 3.4 6.2e-07 29.1 2.3 1.7 1 0 0 1 1 1 1 CHCH domain G-patch PF01585.18 CCD27146.1 - 1.9e-12 46.7 2.8 3.4e-12 45.9 2.0 1.4 1 0 0 1 1 1 1 G-patch domain GCFC PF07842.7 CCD27146.1 - 8.6e-05 22.0 0.5 8.6e-05 22.0 0.4 2.2 1 1 1 2 2 2 2 GC-rich sequence DNA-binding factor-like protein G-patch_2 PF12656.2 CCD27146.1 - 9.2e-05 22.2 0.4 0.00025 20.8 0.3 1.7 1 0 0 1 1 1 1 DExH-box splicing factor binding site NPV_P10 PF05531.7 CCD27146.1 - 5.7 7.2 7.8 6.4 7.0 2.7 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein APG17 PF04108.7 CCD27147.1 - 6.6e-95 318.3 27.9 7.5e-95 318.1 19.4 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 CTP_transf_3 PF02348.14 CCD27147.1 - 0.065 12.8 3.5 0.17 11.4 2.4 1.7 1 0 0 1 1 1 0 Cytidylyltransferase PAZ_siRNAbind PF12212.3 CCD27147.1 - 0.11 12.1 2.2 0.85 9.2 0.2 2.8 2 0 0 2 2 2 0 Piwi/Argonaute/Zwille siRNA-binding domain H-kinase_dim PF02895.9 CCD27147.1 - 0.17 12.2 3.6 0.27 11.6 1.2 2.4 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF2203 PF09969.4 CCD27147.1 - 1.1 9.4 14.3 0.068 13.3 0.6 3.9 2 2 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) PP-binding PF00550.20 CCD27148.1 - 1e-11 44.9 0.3 1.6e-11 44.2 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CCD27148.1 - 3.7e-08 33.2 1.5 6e-08 32.6 1.0 1.4 1 1 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 CCD27148.1 - 0.02 14.9 0.6 0.03 14.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) Ded_cyto PF06920.8 CCD27149.1 - 9.7e-20 70.6 0.8 3.6e-19 68.7 0.6 2.1 1 0 0 1 1 1 1 Dedicator of cytokinesis Seryl_tRNA_N PF02403.17 CCD27149.1 - 0.016 15.2 1.2 0.031 14.2 0.1 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SRP1_TIP1 PF00660.12 CCD27150.1 - 3.8e-35 119.8 0.4 4.6e-35 119.5 0.3 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family Proteasom_Rpn13 PF04683.8 CCD27152.1 - 4e-18 65.2 0.1 7.1e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Amidohydro_4 PF13147.1 CCD27153.1 - 1.2e-08 35.3 0.0 1.6e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 CCD27153.1 - 4e-06 26.5 0.0 8.5e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase OB_NTP_bind PF07717.11 CCD27154.1 - 1.7e-20 72.9 1.4 4.7e-20 71.5 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 CCD27154.1 - 4.6e-13 49.0 2.0 4.6e-13 49.0 1.4 2.5 2 0 0 2 2 2 1 RWD domain Helicase_C PF00271.26 CCD27154.1 - 1.6e-11 43.9 0.1 4.9e-11 42.3 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.18 CCD27154.1 - 1.4e-10 41.1 1.1 9.5e-10 38.4 0.0 2.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.24 CCD27154.1 - 5.2e-10 39.0 0.4 1.9e-09 37.2 0.3 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCD27154.1 - 1.6e-05 25.0 0.1 5.8e-05 23.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CCD27154.1 - 5.8e-05 22.3 0.2 0.0085 15.2 0.0 2.6 2 0 0 2 2 2 1 KaiC NACHT PF05729.7 CCD27154.1 - 0.0002 21.0 1.4 0.00035 20.2 0.1 2.0 2 0 0 2 2 2 1 NACHT domain T2SE PF00437.15 CCD27154.1 - 0.0008 18.3 0.0 0.0019 17.1 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 CCD27154.1 - 0.0017 17.8 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CCD27154.1 - 0.0045 16.9 0.1 0.077 12.9 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CCD27154.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 CCD27154.1 - 0.026 13.7 0.2 0.16 11.1 0.0 2.3 2 1 0 2 2 2 0 PhoH-like protein AAA_25 PF13481.1 CCD27154.1 - 0.031 13.6 0.0 0.084 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CCD27154.1 - 0.032 13.6 0.0 0.066 12.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family CDC73 PF05179.9 CCD27155.1 - 1.5e-70 237.7 5.9 2.8e-70 236.7 4.0 1.5 1 1 1 2 2 2 1 RNA pol II accessory factor, Cdc73 family EAP30 PF04157.11 CCD27156.1 - 3.5e-34 117.9 0.1 1e-33 116.3 0.1 1.9 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CCD27156.1 - 3.4e-33 113.3 1.0 1e-32 111.7 0.3 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 GRAM PF02893.15 CCD27156.1 - 0.00049 19.5 0.0 0.0027 17.1 0.0 2.4 2 0 0 2 2 2 1 GRAM domain zf-Sec23_Sec24 PF04810.10 CCD27156.1 - 0.058 12.9 11.5 0.073 12.6 0.1 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Rubredoxin PF00301.15 CCD27156.1 - 0.088 12.7 2.9 0.73 9.7 0.0 3.1 2 1 1 3 3 3 0 Rubredoxin DZR PF12773.2 CCD27156.1 - 0.089 12.6 9.5 0.39 10.5 6.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon zf-RanBP PF00641.13 CCD27156.1 - 3.1 6.9 8.3 3.2 6.9 0.2 3.2 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others DUF164 PF02591.10 CCD27156.1 - 6.2 6.7 7.5 11 5.9 0.6 3.3 3 0 0 3 3 3 0 Putative zinc ribbon domain OrfB_Zn_ribbon PF07282.6 CCD27156.1 - 6.4 6.5 9.8 0.81 9.3 0.2 3.4 2 1 3 5 5 5 0 Putative transposase DNA-binding domain Cas_CXXC_CXXC PF09706.5 CCD27156.1 - 8.1 6.6 12.2 5.8 7.1 2.4 3.1 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) SUR7 PF06687.7 CCD27157.1 - 7.2e-38 130.2 22.5 1e-37 129.7 15.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family SUR7 PF06687.7 CCD27158.1 - 3.1e-09 36.7 30.9 3.2e-07 30.1 8.1 3.0 2 1 0 2 2 2 2 SUR7/PalI family Acyl_transf_1 PF00698.16 CCD27159.1 - 3e-97 325.7 0.0 1.5e-95 320.2 0.0 3.1 4 0 0 4 4 4 1 Acyl transferase domain MaoC_dehydratas PF01575.14 CCD27159.1 - 7.1e-36 122.2 0.0 1.3e-35 121.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 CCD27159.1 - 8e-30 102.4 0.2 2.4e-29 100.9 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 CCD27159.1 - 2.3e-17 63.0 0.0 5.6e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 CCD27159.1 - 0.00061 19.0 0.1 0.0086 15.2 0.1 2.7 1 1 0 1 1 1 1 Nitronate monooxygenase SRR1 PF07985.7 CCD27160.1 - 4.6e-14 52.0 0.3 1.2e-13 50.7 0.2 1.7 1 1 0 1 1 1 1 SRR1 RNR_inhib PF08591.5 CCD27161.1 - 4.2e-08 34.0 2.8 5.1e-08 33.7 0.3 2.3 2 1 0 2 2 2 1 Ribonucleotide reductase inhibitor Aminotran_3 PF00202.16 CCD27162.1 - 1.2e-107 359.6 0.0 1.4e-107 359.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CCD27162.1 - 0.00012 21.3 0.0 0.00018 20.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase LSM PF01423.17 CCD27163.1 - 3.3e-18 64.9 0.1 4.1e-18 64.6 0.1 1.1 1 0 0 1 1 1 1 LSM domain Fe_dep_repress PF01325.14 CCD27163.1 - 0.013 15.4 0.1 0.028 14.3 0.0 1.5 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain SM-ATX PF14438.1 CCD27163.1 - 0.064 13.1 0.0 0.078 12.9 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain DUF879 PF05947.7 CCD27163.1 - 0.069 11.4 0.0 0.075 11.3 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF879) MRP-L47 PF06984.8 CCD27164.1 - 1.3e-18 66.6 1.7 3.6e-18 65.2 1.2 1.8 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Gemini_AL1 PF00799.15 CCD27164.1 - 0.05 13.4 1.4 1.1 9.1 0.1 2.6 2 0 0 2 2 2 0 Geminivirus Rep catalytic domain EntA_Immun PF08951.5 CCD27164.1 - 0.83 9.8 7.9 0.21 11.7 1.1 2.8 3 0 0 3 3 3 0 Enterocin A Immunity Ribosomal_S3Ae PF01015.13 CCD27165.1 - 3.4e-81 271.2 7.3 4e-81 271.0 5.0 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 CCD27165.1 - 0.043 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region SpoVIF PF14069.1 CCD27165.1 - 0.33 10.7 2.8 4.7 7.0 0.6 2.5 1 1 1 2 2 2 0 Stage VI sporulation protein F BAH PF01426.13 CCD27166.1 - 3.5e-17 62.2 0.4 1.2e-16 60.5 0.3 2.0 1 0 0 1 1 1 1 BAH domain AAA PF00004.24 CCD27166.1 - 4.9e-09 36.4 0.0 1.8e-08 34.6 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCD27166.1 - 4e-05 23.6 0.0 0.0044 17.0 0.0 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCD27166.1 - 0.00066 19.8 0.3 0.0061 16.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain COPIIcoated_ERV PF07970.7 CCD27168.1 - 9.1e-23 81.0 0.0 1.6e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCD27168.1 - 7.9e-19 67.4 0.1 1.7e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1765 PF08578.5 CCD27169.1 - 0.052 13.6 0.2 0.073 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) DUF1374 PF07118.6 CCD27169.1 - 0.076 13.1 2.7 0.12 12.4 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1374) Syntaxin_2 PF14523.1 CCD27169.1 - 1.4 8.9 5.0 5.2 7.1 0.8 2.6 3 1 0 3 3 3 0 Syntaxin-like protein MscS_porin PF12795.2 CCD27170.1 - 0.072 12.3 0.4 0.072 12.3 0.3 2.1 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain LRAT PF04970.8 CCD27170.1 - 1.2 9.0 5.9 21 5.0 2.7 2.7 2 1 0 2 2 2 0 Lecithin retinol acyltransferase Hexokinase_1 PF00349.16 CCD27171.1 - 1.6e-10 40.6 0.1 3.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 CCD27171.1 - 5.2e-08 32.3 0.0 1e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Hexokinase vATP-synt_AC39 PF01992.11 CCD27172.1 - 1.5e-83 280.7 0.3 1.8e-83 280.4 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_L6e PF01159.14 CCD27173.1 - 1.2e-39 134.8 3.2 1.8e-39 134.3 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Piwi PF02171.12 CCD27174.1 - 5.2e-69 232.5 1.1 5.4e-69 232.4 0.1 1.5 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.17 CCD27174.1 - 3.7e-06 26.2 0.0 9.8e-06 24.9 0.0 1.7 1 0 0 1 1 1 1 PAZ domain FKBP_C PF00254.23 CCD27175.1 - 3e-28 97.6 0.1 6.1e-27 93.4 0.0 2.7 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase LMBR1 PF04791.11 CCD27175.1 - 0.3 9.6 3.6 0.44 9.0 2.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_M28 PF04389.12 CCD27176.1 - 4.2e-11 42.9 0.0 8e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 CCD27176.1 - 3.4e-10 39.5 0.0 8.4e-10 38.3 0.0 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CCD27176.1 - 0.00037 20.1 0.0 0.00068 19.2 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-H2C2_2 PF13465.1 CCD27177.1 - 1.6e-06 28.1 10.7 2.7e-05 24.2 3.2 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 CCD27177.1 - 5e-05 23.3 11.0 0.0041 17.3 1.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD27177.1 - 0.013 15.7 11.3 0.21 12.0 1.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Methyltransf_16 PF10294.4 CCD27178.1 - 1.5e-23 83.1 0.3 2.7e-23 82.2 0.2 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 CCD27178.1 - 0.015 14.6 0.0 0.038 13.3 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Glyco_hydro_47 PF01532.15 CCD27179.1 - 5.6e-132 440.5 0.4 6.7e-132 440.3 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 IBN_N PF03810.14 CCD27180.1 - 2.4e-17 62.5 1.2 2.4e-17 62.5 0.9 4.3 4 0 0 4 4 4 1 Importin-beta N-terminal domain PhageMin_Tail PF10145.4 CCD27180.1 - 0.06 12.9 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Phage-related minor tail protein Herpes_pp85 PF04637.7 CCD27181.1 - 0.024 12.9 0.4 0.038 12.2 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Pribosyltran PF00156.22 CCD27182.1 - 2.8e-14 52.9 0.7 2.7e-13 49.7 0.5 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain NOT2_3_5 PF04153.13 CCD27182.1 - 0.13 12.1 0.0 0.43 10.4 0.0 1.8 2 0 0 2 2 2 0 NOT2 / NOT3 / NOT5 family Sec39 PF08314.6 CCD27183.1 - 1.5e-104 350.4 19.9 1.8e-104 350.2 13.8 1.1 1 0 0 1 1 1 1 Secretory pathway protein Sec39 TMF_TATA_bd PF12325.3 CCD27184.1 - 4e-34 116.9 16.2 4e-34 116.9 11.2 5.7 2 1 3 6 6 6 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 CCD27184.1 - 6e-14 51.6 13.1 6e-14 51.6 9.1 8.8 4 2 5 9 9 8 3 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CCD27184.1 - 1.1e-09 38.2 82.8 0.00017 21.2 13.6 4.9 2 1 2 4 4 4 3 IncA protein Seryl_tRNA_N PF02403.17 CCD27184.1 - 2.5e-05 24.2 4.2 2.5e-05 24.2 2.9 6.6 2 2 2 5 5 5 1 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 CCD27184.1 - 0.00023 20.9 17.8 0.00023 20.9 12.3 6.2 2 2 4 6 6 6 2 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 CCD27184.1 - 0.00023 19.0 16.4 0.00023 19.0 11.4 3.3 2 1 1 3 3 3 2 Myosin tail DUF3584 PF12128.3 CCD27184.1 - 0.0037 14.6 69.7 0.0086 13.4 10.5 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3584) HOOK PF05622.7 CCD27184.1 - 0.0064 14.3 77.2 0.0028 15.5 5.7 3.7 2 1 1 3 3 3 2 HOOK protein CENP-F_leu_zip PF10473.4 CCD27184.1 - 0.018 14.9 92.4 0.052 13.4 12.0 5.8 2 1 4 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 CCD27184.1 - 0.018 15.2 4.0 0.018 15.2 2.7 7.5 4 2 2 6 6 6 0 Nucleopolyhedrovirus P10 protein Cast PF10174.4 CCD27184.1 - 0.084 10.9 81.4 0.027 12.5 9.2 3.9 2 1 1 3 3 3 0 RIM-binding protein of the cytomatrix active zone Spc7 PF08317.6 CCD27184.1 - 0.26 9.8 88.1 1.1 7.8 9.6 4.8 2 2 2 4 4 4 0 Spc7 kinetochore protein Filament PF00038.16 CCD27184.1 - 0.48 9.8 70.5 41 3.4 8.1 4.8 2 2 0 2 2 2 0 Intermediate filament protein Lebercilin PF15619.1 CCD27184.1 - 0.78 9.1 79.6 0.0096 15.3 10.4 4.6 2 1 2 4 4 3 0 Ciliary protein causing Leber congenital amaurosis disease Fez1 PF06818.10 CCD27184.1 - 0.91 9.5 55.9 0.13 12.2 11.3 4.3 2 1 1 4 4 4 0 Fez1 Atg14 PF10186.4 CCD27184.1 - 0.92 8.3 71.8 0.013 14.4 7.5 4.4 2 1 2 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4164 PF13747.1 CCD27184.1 - 1 9.5 47.2 0.03 14.4 3.4 5.8 4 3 1 5 5 5 0 Domain of unknown function (DUF4164) Tropomyosin_1 PF12718.2 CCD27184.1 - 2.5 7.9 87.2 0.47 10.2 10.6 5.7 3 1 1 5 5 4 0 Tropomyosin like GAS PF13851.1 CCD27184.1 - 2.7 7.1 89.4 1.6 7.9 8.0 6.1 3 1 4 7 7 7 0 Growth-arrest specific micro-tubule binding DUF3407 PF11887.3 CCD27184.1 - 4.3 6.5 16.8 0.03 13.6 3.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3407) Mnd1 PF03962.10 CCD27184.1 - 8.5 5.9 68.5 0.64 9.6 7.4 5.3 2 1 1 4 4 3 0 Mnd1 family Muted PF14942.1 CCD27185.1 - 1.8 8.4 6.2 0.61 9.9 0.3 2.1 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein zf-Tim10_DDP PF02953.10 CCD27186.1 - 6.2e-21 73.4 2.1 8.2e-21 73.0 1.4 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger ATP11 PF06644.6 CCD27186.1 - 0.038 13.4 1.5 0.38 10.1 0.0 2.0 1 1 1 2 2 2 0 ATP11 protein DUF2454 PF10521.4 CCD27187.1 - 1.3e-52 178.5 11.1 1.9e-52 178.0 7.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Aminotran_4 PF01063.14 CCD27188.1 - 3.5e-30 105.1 0.0 4.4e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Ribosomal_S4e PF00900.15 CCD27189.1 - 5.5e-33 112.4 1.5 3e-32 110.1 0.6 2.1 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CCD27189.1 - 6.9e-20 70.6 4.4 1.4e-19 69.6 3.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CCD27189.1 - 1.4e-07 30.8 0.5 2.6e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 CCD27189.1 - 1e-05 25.0 1.9 1e-05 25.0 1.3 3.3 4 0 0 4 4 4 1 KOW motif PMT PF02366.13 CCD27190.1 - 1.2e-79 267.1 20.1 2.5e-79 266.1 13.9 1.6 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCD27190.1 - 8.7e-25 87.3 0.1 1.4e-24 86.7 0.0 1.3 1 0 0 1 1 1 1 MIR domain DUF1725 PF08333.6 CCD27190.1 - 0.057 12.7 1.9 0.12 11.6 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) NUDIX PF00293.23 CCD27191.1 - 6.8e-06 25.7 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain HECT_2 PF09814.4 CCD27192.1 - 9.4e-68 228.4 0.1 1.1e-67 228.3 0.0 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding TPR_6 PF13174.1 CCD27193.1 - 0.088 13.3 1.1 4.7 7.8 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3608 PF12257.3 CCD27194.1 - 3.9e-134 445.9 7.4 3.9e-134 445.9 5.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3608) DEP PF00610.16 CCD27194.1 - 2.8e-26 91.0 0.5 6.4e-26 89.9 0.3 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NIR_SIR PF01077.17 CCD27195.1 - 5.6e-50 168.7 0.0 7.3e-45 152.1 0.0 2.5 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 CCD27195.1 - 6.1e-28 96.2 0.1 2.8e-13 49.2 0.0 2.7 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 CCD27195.1 - 1e-25 90.3 0.0 2.5e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin Sir1 PF11603.3 CCD27196.1 - 9.4e-26 90.4 7.3 6.8e-11 42.4 0.4 3.5 3 1 0 3 3 3 3 Regulatory protein Sir1 Use1 PF09753.4 CCD27196.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Membrane fusion protein Use1 C-C_Bond_Lyase PF15617.1 CCD27196.1 - 0.069 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 C-C_Bond_Lyase of the TIM-Barrel fold Flo11 PF10182.4 CCD27198.1 - 1.5e-48 164.1 0.2 2.5e-48 163.4 0.1 1.4 1 0 0 1 1 1 1 Flo11 domain Helicase_C PF00271.26 CCD27200.1 - 3.8e-12 45.9 0.0 1.1e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD27200.1 - 7.5e-06 25.5 0.0 1.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_30 PF13604.1 CCD27200.1 - 0.28 10.7 0.0 0.71 9.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain Helicase_C PF00271.26 CCD27201.1 - 1.3e-12 47.3 0.0 3.5e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD27201.1 - 3.7e-10 39.5 0.0 9.3e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sir1 PF11603.3 CCD27201.1 - 4.2e-09 36.6 0.1 9.9e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 Regulatory protein Sir1 Ribonuclease_3 PF00636.21 CCD27203.1 - 2.5e-20 73.0 0.1 1.1e-19 70.9 0.0 2.2 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCD27203.1 - 3.5e-15 56.0 0.0 8.8e-15 54.8 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 CCD27203.1 - 6.8e-10 39.3 0.0 3.4e-07 30.7 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif Gemin6 PF06372.7 CCD27203.1 - 0.063 12.6 0.0 0.17 11.1 0.0 1.6 2 0 0 2 2 2 0 Gemin6 protein Fungal_trans_2 PF11951.3 CCD27204.1 - 3e-109 365.1 2.8 4.1e-109 364.6 1.9 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD27204.1 - 1.1e-11 44.4 8.9 2e-11 43.5 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2363 PF10155.4 CCD27204.1 - 0.067 13.1 3.8 3.5 7.5 0.6 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) ERO1 PF04137.10 CCD27205.1 - 3.7e-108 361.7 8.2 4.6e-108 361.4 5.7 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) ImcF-related_N PF14331.1 CCD27205.1 - 0.057 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 ImcF-related N-terminal domain VPS9 PF02204.13 CCD27206.1 - 9.1e-28 96.3 0.2 2.7e-27 94.8 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 CCD27206.1 - 4e-11 42.1 0.0 7.9e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain Asn_synthase PF00733.16 CCD27207.1 - 5.6e-46 157.1 0.0 7.8e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CCD27207.1 - 5e-11 42.4 0.7 5.6e-09 35.7 0.0 3.4 3 1 0 3 3 3 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CCD27207.1 - 9.6e-05 22.3 0.0 0.00057 19.8 0.0 2.3 2 1 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CCD27207.1 - 0.027 13.6 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 Aluminium induced protein DUF4448 PF14610.1 CCD27207.1 - 0.051 13.0 0.2 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rad10 PF03834.9 CCD27208.1 - 1.8e-26 91.6 1.7 2.6e-26 91.0 1.2 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Prefoldin PF02996.12 CCD27209.1 - 1.8e-24 85.6 1.4 1.8e-24 85.6 1.0 1.4 1 1 0 1 1 1 1 Prefoldin subunit DUF4463 PF14703.1 CCD27209.1 - 0.055 14.0 0.7 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) Utp14 PF04615.8 CCD27210.1 - 1.2e-208 694.8 81.1 1.2e-208 694.8 56.2 2.1 1 1 1 2 2 2 1 Utp14 protein RPM2 PF08579.6 CCD27211.1 - 9.6e-41 138.6 3.7 9.6e-41 138.6 2.6 5.9 5 2 0 6 6 6 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.1 CCD27211.1 - 0.001 19.0 1.6 6.1 6.9 0.1 5.1 5 0 0 5 5 5 2 PPR repeat family HMG_CoA_synt_C PF08540.5 CCD27212.1 - 2.5e-108 361.8 3.3 3.2e-108 361.5 2.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 CCD27212.1 - 9.1e-95 315.1 0.2 1.3e-94 314.6 0.2 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal F-box-like PF12937.2 CCD27213.1 - 2.9e-11 42.9 0.1 5.1e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCD27213.1 - 9.1e-06 25.1 0.1 1.8e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 CCD27213.1 - 0.00053 19.3 1.9 0.00053 19.3 1.3 5.4 6 0 0 6 6 6 3 Ubiquitin interaction motif ALO PF04030.9 CCD27214.1 - 7.1e-87 291.2 0.6 8.8e-87 290.9 0.4 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CCD27214.1 - 1.6e-26 92.4 0.1 2.3e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain SUD-M PF11633.3 CCD27214.1 - 0.0037 16.5 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 1 Single-stranded poly(A) binding domain BBE PF08031.7 CCD27214.1 - 0.0088 15.9 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Tubulin PF00091.20 CCD27216.1 - 4.7e-71 239.0 0.0 6.4e-71 238.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCD27216.1 - 1.1e-48 164.4 0.1 1.8e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Sugar_tr PF00083.19 CCD27217.1 - 9.7e-43 146.3 15.6 1.4e-42 145.8 10.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD27217.1 - 7.1e-21 74.3 12.5 8.5e-13 47.7 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BRI3BP PF14965.1 CCD27217.1 - 0.11 11.8 0.4 0.29 10.4 0.2 1.7 1 0 0 1 1 1 0 Negative regulator of p53/TP53 SQS_PSY PF00494.14 CCD27218.1 - 6.8e-42 143.5 0.0 8.3e-42 143.3 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Hyphal_reg_CWP PF11765.3 CCD27219.1 - 2.6e-17 62.6 15.6 2.6e-17 62.6 10.8 2.0 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal B_lectin PF01453.19 CCD27219.1 - 0.86 9.5 6.6 4.6 7.1 2.4 3.2 2 1 0 2 2 2 0 D-mannose binding lectin Pept_tRNA_hydro PF01195.14 CCD27220.1 - 5.1e-43 146.6 0.0 6.2e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase RNB PF00773.14 CCD27221.1 - 4.7e-61 206.8 2.7 4.5e-60 203.6 1.9 2.4 1 1 0 1 1 1 1 RNB domain Flocculin PF00624.13 CCD27221.1 - 0.0054 16.5 0.6 0.017 14.9 0.4 1.8 1 0 0 1 1 1 1 Flocculin repeat PIG-L PF02585.12 CCD27222.1 - 2.9e-19 69.8 0.0 4.1e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase ATP13 PF12921.2 CCD27223.1 - 2.4e-17 62.4 1.6 7.2e-17 60.9 0.2 2.3 2 0 0 2 2 2 1 Mitochondrial ATPase expression YjgP_YjgQ PF03739.9 CCD27223.1 - 0.0053 15.5 0.8 0.01 14.5 0.6 1.8 1 1 0 1 1 1 1 Predicted permease YjgP/YjgQ family PPR_3 PF13812.1 CCD27223.1 - 0.019 15.1 0.0 24 5.5 0.0 3.5 3 0 0 3 3 3 0 Pentatricopeptide repeat domain RasGEF_N PF00618.15 CCD27223.1 - 0.18 11.9 3.1 0.25 11.4 0.0 2.8 3 1 0 3 3 3 0 RasGEF N-terminal motif Init_tRNA_PT PF04179.7 CCD27224.1 - 2.5e-147 491.4 0.5 2.9e-147 491.2 0.3 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase DSPc PF00782.15 CCD27224.1 - 0.0035 16.9 0.1 0.011 15.3 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain RVT_1 PF00078.22 CCD27225.1 - 3.9e-26 91.7 0.1 7.5e-26 90.8 0.1 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCD27225.1 - 4.4e-19 68.7 0.0 1.5e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Peptidase_A2B PF12384.3 CCD27225.1 - 1.8e-17 63.2 0.1 4.1e-17 62.0 0.1 1.5 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.1 CCD27225.1 - 7.7e-05 23.1 0.0 0.00016 22.0 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 CCD27225.1 - 0.0013 18.4 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-H2C2 PF09337.5 CCD27225.1 - 0.0027 17.0 2.0 0.066 12.6 0.2 2.9 2 0 0 2 2 2 1 His(2)-Cys(2) zinc finger Retrotrans_gag PF03732.12 CCD27226.1 - 6.6e-05 22.9 0.1 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CCD27226.1 - 0.002 17.9 6.0 0.0038 17.0 4.2 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CCD27226.1 - 0.077 12.7 3.2 0.16 11.7 2.2 1.5 1 0 0 1 1 1 0 Zinc knuckle Ku PF02735.11 CCD27227.1 - 4.7e-34 117.5 0.2 1.1e-33 116.3 0.1 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CCD27227.1 - 2.9e-27 95.5 1.3 6.7e-27 94.3 0.9 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 CCD27227.1 - 1.1e-09 38.6 2.9 1.3e-09 38.4 0.6 2.3 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm Exo_endo_phos PF03372.18 CCD27228.1 - 5e-22 79.0 0.0 6.4e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family B_lectin PF01453.19 CCD27229.1 - 0.53 10.1 3.5 5.6 6.8 2.4 2.4 1 1 0 1 1 1 0 D-mannose binding lectin Fungal_trans PF04082.13 CCD27230.1 - 5.6e-24 84.4 14.3 5.6e-24 84.4 9.9 2.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCD27230.1 - 3.7e-10 39.5 13.3 6.7e-10 38.7 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 CCD27231.1 - 2.5e-32 112.0 59.6 1.5e-31 109.4 39.0 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCD27231.1 - 8.4e-09 34.5 30.6 2.1e-05 23.2 5.9 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter DUF843 PF05814.6 CCD27231.1 - 4.4 7.1 6.5 0.84 9.4 1.2 2.4 2 0 0 2 2 2 0 Baculovirus protein of unknown function (DUF843) PGM_PMM_I PF02878.11 CCD27232.1 - 9e-41 138.5 0.0 2.2e-40 137.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CCD27232.1 - 4.6e-20 71.8 0.0 9.7e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CCD27232.1 - 3.1e-12 46.5 0.0 5.8e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CCD27232.1 - 1.1e-05 25.3 0.0 3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain NIF PF03031.13 CCD27233.1 - 7.4e-26 90.7 1.0 1.5e-24 86.4 0.0 2.8 2 1 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 CCD27233.1 - 8.1e-12 45.1 0.1 2.2e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCD27233.1 - 2.4e-06 27.3 0.0 5.7e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain Transposase_mut PF00872.13 CCD27234.1 - 2.3e-05 23.1 0.4 3.8e-05 22.4 0.1 1.4 2 0 0 2 2 2 1 Transposase, Mutator family IPPT PF01715.12 CCD27234.1 - 0.0011 18.0 0.9 0.0027 16.7 0.1 1.8 2 0 0 2 2 2 1 IPP transferase MULE PF10551.4 CCD27234.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain ubiquitin PF00240.18 CCD27235.1 - 2.1e-17 62.2 0.1 3.5e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCD27235.1 - 3.7e-09 36.1 0.1 6.4e-09 35.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 CCD27235.1 - 6.4e-09 35.4 0.1 6.4e-09 35.4 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain CUE PF02845.11 CCD27235.1 - 0.0017 17.7 0.0 0.0036 16.7 0.0 1.6 1 0 0 1 1 1 1 CUE domain DUF2407 PF10302.4 CCD27235.1 - 0.0031 17.6 0.1 0.007 16.5 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Ubiquitin_2 PF14560.1 CCD27235.1 - 0.0032 17.6 0.2 0.0078 16.4 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 CCD27235.1 - 0.01 15.7 0.1 0.03 14.2 0.1 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Apc15p PF05841.6 CCD27235.1 - 3.8 8.2 10.1 10 6.8 4.4 2.6 2 0 0 2 2 2 0 Apc15p protein Menin PF05053.8 CCD27235.1 - 5.3 5.0 7.6 9.3 4.2 5.2 1.3 1 0 0 1 1 1 0 Menin Bul1_N PF04425.7 CCD27236.1 - 1.1e-158 528.3 7.8 1.1e-158 528.3 5.4 3.3 3 0 0 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 CCD27236.1 - 1.6e-96 322.6 25.4 1.6e-96 322.6 17.6 4.5 3 2 0 4 4 4 1 Bul1 C terminus Abi PF02517.11 CCD27237.1 - 1.8e-11 43.9 7.7 3.7e-11 43.0 5.3 1.6 1 1 0 1 1 1 1 CAAX protease self-immunity Cyt-b5 PF00173.23 CCD27238.1 - 2.3e-14 52.9 0.2 8.4e-14 51.1 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CCD27238.1 - 2.2e-10 40.9 17.7 2.2e-10 40.9 12.2 2.1 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 CCD27238.1 - 0.029 14.3 0.5 0.082 12.9 0.1 1.9 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region RL11D PF11088.3 CCD27238.1 - 0.11 12.3 0.1 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 Pribosyltran PF00156.22 CCD27239.1 - 5e-17 61.8 0.4 9e-17 60.9 0.1 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain RRN9 PF10680.4 CCD27240.1 - 6.4e-16 57.8 0.9 1.3e-15 56.8 0.2 1.9 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor G-patch PF01585.18 CCD27241.1 - 0.00069 19.3 0.4 0.0033 17.1 0.3 2.2 1 0 0 1 1 1 1 G-patch domain GAGA_bind PF06217.7 CCD27241.1 - 0.11 12.4 19.8 0.13 12.1 13.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CCD27241.1 - 0.16 11.8 17.6 0.21 11.4 12.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 CCD27241.1 - 0.81 8.6 5.0 0.99 8.3 3.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter U79_P34 PF03064.11 CCD27241.1 - 3.4 7.1 26.6 5 6.5 18.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2201_N PF13203.1 CCD27241.1 - 5.8 5.9 12.9 7.4 5.6 9.0 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain CDC45 PF02724.9 CCD27241.1 - 7.8 4.3 26.3 10 3.9 18.2 1.0 1 0 0 1 1 1 0 CDC45-like protein RRM_1 PF00076.17 CCD27242.1 - 7.3e-36 121.6 1.3 4.6e-14 51.7 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD27242.1 - 1.3e-28 98.7 1.2 4.6e-10 39.3 0.0 4.2 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD27242.1 - 4.1e-17 61.7 0.5 1.2e-06 28.2 0.0 3.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 CCD27242.1 - 8.3e-07 28.1 0.7 3.1e-06 26.3 0.5 2.1 1 0 0 1 1 1 1 Lsm interaction motif Nup35_RRM_2 PF14605.1 CCD27242.1 - 0.00013 21.6 0.0 0.25 11.1 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Pyrophosphatase PF00719.14 CCD27243.1 - 1.7e-52 176.9 0.1 2.4e-52 176.5 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase SNAP PF14938.1 CCD27244.1 - 3.7e-105 351.1 8.4 4.1e-105 350.9 5.9 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CCD27244.1 - 2.1e-05 24.3 3.1 0.056 13.3 0.3 3.5 1 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCD27244.1 - 0.003 17.8 2.2 58 4.4 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCD27244.1 - 0.035 13.7 10.3 0.71 9.5 0.2 3.9 2 1 3 5 5 5 0 TPR repeat TPR_7 PF13176.1 CCD27244.1 - 0.038 13.7 0.5 2.1 8.3 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCD27244.1 - 0.041 13.4 3.1 30 4.4 0.0 5.2 5 2 1 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCD27244.1 - 0.07 12.9 6.3 4.4 7.3 0.1 4.9 3 2 1 5 5 5 0 Tetratricopeptide repeat DUF4351 PF14261.1 CCD27244.1 - 0.1 12.4 0.2 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) DUF221 PF02714.10 CCD27245.1 - 2.3e-110 368.5 27.2 4.3e-110 367.5 18.8 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCD27245.1 - 1.2e-40 138.6 2.3 1.2e-40 138.6 1.6 2.4 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CCD27245.1 - 6e-26 90.1 0.0 1.7e-25 88.6 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 CCD27245.1 - 3.5e-12 46.6 1.2 6.9e-12 45.7 0.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF4618 PF15397.1 CCD27245.1 - 0.0032 16.8 0.8 0.0054 16.1 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4618) DUF2410 PF10307.4 CCD27246.1 - 5.8e-46 156.3 1.6 1.4e-44 151.8 1.1 2.2 1 1 0 1 1 1 1 Hypothetical protein (DUF2410) CUE PF02845.11 CCD27247.1 - 3.9e-09 35.8 0.0 7.4e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 CUE domain Shisa PF13908.1 CCD27247.1 - 0.0058 16.8 0.4 0.0078 16.4 0.3 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SAP30_Sin3_bdg PF13867.1 CCD27248.1 - 3.5e-10 39.5 0.3 3.5e-10 39.5 0.2 2.9 2 1 1 3 3 3 2 Sin3 binding region of histone deacetylase complex subunit SAP30 Med3 PF11593.3 CCD27248.1 - 0.025 13.8 4.1 0.024 13.9 2.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3439 PF11921.3 CCD27248.1 - 6.3 6.5 9.6 9.5 5.9 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TatD_DNase PF01026.16 CCD27249.1 - 1.6e-37 129.1 0.4 2e-37 128.8 0.3 1.1 1 0 0 1 1 1 1 TatD related DNase eIF-1a PF01176.14 CCD27250.1 - 1.6e-27 94.6 0.2 2.3e-27 94.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 CCD27250.1 - 0.0045 17.0 0.0 0.0097 15.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF2428 PF10350.4 CCD27251.1 - 2.3e-65 220.1 0.6 2.3e-64 216.8 0.1 2.8 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 CCD27251.1 - 1.6e-06 27.6 0.0 0.77 10.0 0.0 6.3 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 CCD27251.1 - 0.014 15.6 0.0 1.4 9.2 0.0 3.4 4 0 0 4 4 4 0 HEAT repeats F-box-like PF12937.2 CCD27252.1 - 0.6 9.8 3.8 0.31 10.8 0.3 2.3 2 0 0 2 2 2 0 F-box-like CS PF04969.11 CCD27254.1 - 0.0089 16.5 0.4 0.018 15.6 0.0 1.7 2 0 0 2 2 2 1 CS domain SR-25 PF10500.4 CCD27256.1 - 0.021 14.2 17.0 0.026 13.9 11.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_LMP2 PF07415.6 CCD27256.1 - 0.37 9.3 2.4 0.46 9.0 1.6 1.0 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF4661 PF15576.1 CCD27256.1 - 4.3 6.9 6.3 5.6 6.5 4.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4661) EamA PF00892.15 CCD27257.1 - 2.5e-29 101.8 28.6 1.7e-16 60.4 4.2 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CCD27257.1 - 1.6e-07 31.5 10.4 1.6e-07 31.5 7.2 3.4 2 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 CCD27257.1 - 3.7e-07 29.3 14.2 6.9e-07 28.4 9.8 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 CCD27257.1 - 1.1e-05 24.4 16.0 3.9e-05 22.7 2.1 2.5 1 1 1 2 2 2 2 UAA transporter family UPF0546 PF10639.4 CCD27257.1 - 0.69 9.7 6.0 0.65 9.8 1.3 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 TPT PF03151.11 CCD27257.1 - 1.2 8.7 20.7 0.061 12.9 4.5 2.6 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF3270 PF11674.3 CCD27257.1 - 3.5 7.7 7.1 21 5.1 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3270) UPF0060 PF02694.10 CCD27257.1 - 5.8 6.9 11.8 13 5.8 0.4 2.8 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Paramyxo_PNT PF13825.1 CCD27259.1 - 0.14 11.3 2.4 0.15 11.2 1.7 1.0 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus TMP-TENI PF02581.12 CCD27259.1 - 0.15 11.1 0.7 0.16 11.0 0.5 1.0 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI DUF202 PF02656.10 CCD27259.1 - 1.5 9.1 4.4 1.8 8.8 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Pyridoxal_deC PF00282.14 CCD27260.1 - 4.4e-52 176.7 0.0 6.7e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SAM_decarbox PF01536.11 CCD27261.1 - 7e-115 383.2 5.7 8.4e-115 382.9 3.9 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase zf-RING_2 PF13639.1 CCD27262.1 - 1.8e-08 34.0 6.7 3.5e-08 33.1 4.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCD27262.1 - 1.8e-07 31.1 3.2 4.2e-07 29.9 2.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 CCD27262.1 - 2.6e-05 24.0 5.5 8.7e-05 22.4 3.8 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 CCD27262.1 - 0.00013 21.7 1.2 0.00031 20.5 0.9 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CCD27262.1 - 0.0045 16.6 8.0 0.0099 15.5 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 CCD27262.1 - 0.012 15.6 6.3 0.025 14.6 4.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 CCD27262.1 - 0.069 13.1 8.1 0.15 12.1 5.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CCD27262.1 - 0.071 12.7 5.4 0.51 9.9 0.6 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CCD27262.1 - 0.14 11.8 6.4 2.1 8.1 4.4 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CCD27262.1 - 0.41 10.4 2.3 3.4 7.4 0.3 2.4 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-RING-like PF08746.6 CCD27262.1 - 0.8 9.7 6.5 1.8 8.6 4.5 1.6 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 CCD27262.1 - 5 6.9 6.5 11 5.8 4.5 1.6 1 0 0 1 1 1 0 PHD-finger Glyco_transf_8 PF01501.15 CCD27263.1 - 4e-08 32.9 2.9 4e-08 32.9 2.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CCD27263.1 - 0.0031 16.9 0.1 0.006 15.9 0.1 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative AMP-binding PF00501.23 CCD27265.1 - 7.8e-78 261.7 0.0 1e-77 261.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Terminase_3 PF04466.8 CCD27265.1 - 0.0096 15.0 0.2 0.035 13.1 0.0 1.8 2 0 0 2 2 2 1 Phage terminase large subunit AMP-binding_C PF13193.1 CCD27265.1 - 0.021 15.7 0.1 0.11 13.4 0.0 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain COX6B PF02297.12 CCD27266.1 - 1.3e-22 79.6 7.0 1.7e-22 79.2 4.9 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 CCD27266.1 - 0.26 11.3 3.1 0.89 9.6 2.1 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Bac_rhodopsin PF01036.13 CCD27267.1 - 5.2e-45 153.4 21.4 6.6e-45 153.1 14.8 1.1 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 CCD27267.1 - 0.21 10.9 11.5 0.81 9.0 2.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) MerE PF05052.7 CCD27267.1 - 0.31 11.0 2.5 6.8 6.7 0.0 2.4 2 0 0 2 2 2 0 MerE protein DUF2370 PF10176.4 CCD27267.1 - 0.41 9.9 1.7 0.59 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) SUN PF03856.8 CCD27268.1 - 7.2e-76 254.7 14.8 1e-75 254.2 10.2 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Cation_efflux PF01545.16 CCD27269.1 - 5.4e-82 275.0 1.9 6.5e-82 274.8 1.3 1.1 1 0 0 1 1 1 1 Cation efflux family TcpE PF12648.2 CCD27269.1 - 0.96 9.6 5.2 2.2 8.4 0.1 2.6 2 1 1 3 3 3 0 TcpE family Ribosomal_L18ae PF01775.12 CCD27270.1 - 7.9e-57 190.5 2.1 1.2e-56 189.9 1.5 1.3 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Mito_carr PF00153.22 CCD27271.1 - 1.2e-30 105.0 5.5 6.6e-12 44.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF382 PF04037.8 CCD27272.1 - 1.3e-48 164.1 0.3 1.3e-48 164.1 0.2 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.11 CCD27272.1 - 1.8e-14 52.8 0.8 5.1e-14 51.3 0.5 1.8 1 1 0 1 1 1 1 PSP Mut7-C PF01927.11 CCD27272.1 - 0.73 9.8 3.3 2 8.3 2.0 1.9 1 1 1 2 2 2 0 Mut7-C RNAse domain Ribonuclease_3 PF00636.21 CCD27273.1 - 7.5e-18 65.0 0.0 7.5e-18 65.0 0.0 2.8 2 1 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCD27273.1 - 8e-11 42.0 0.0 2.2e-10 40.5 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 CCD27273.1 - 9.2e-05 22.9 0.1 0.00028 21.3 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif Clp1 PF06807.9 CCD27273.1 - 0.81 9.4 3.2 2.5 7.8 0.8 2.3 1 1 0 2 2 2 0 Pre-mRNA cleavage complex II protein Clp1 RCC1 PF00415.13 CCD27274.1 - 1.2e-16 60.5 0.0 1.9e-09 37.5 0.0 4.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CCD27274.1 - 2.8e-14 53.0 1.6 4e-09 36.4 0.5 2.9 2 0 0 2 2 2 2 BTB/POZ domain RCC1_2 PF13540.1 CCD27274.1 - 6e-09 35.2 7.3 0.0039 16.7 0.7 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Glyco_hydro_76 PF03663.9 CCD27275.1 - 8.8e-149 495.8 17.6 1.1e-148 495.5 12.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TFIID-31kDa PF02291.10 CCD27276.1 - 1.3e-51 173.7 0.4 1.8e-27 95.6 0.0 2.1 2 0 0 2 2 2 2 Transcription initiation factor IID, 31kD subunit APC_CDC26 PF10471.4 CCD27276.1 - 0.089 13.5 3.9 0.35 11.6 2.7 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 MBF1 PF08523.5 CCD27277.1 - 2.4e-26 91.5 1.1 2.4e-26 91.5 0.7 1.7 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 CCD27277.1 - 2.5e-14 52.8 0.3 3.9e-14 52.2 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 CCD27277.1 - 2e-06 27.7 0.1 2.9e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 CCD27277.1 - 2.3e-06 27.7 0.0 4.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain DBP PF12361.3 CCD27277.1 - 0.0094 15.5 0.8 0.011 15.3 0.5 1.1 1 0 0 1 1 1 1 Duffy-antigen binding protein LRR_6 PF13516.1 CCD27278.1 - 8.5e-11 40.7 17.6 0.097 12.7 0.1 8.3 9 0 0 9 9 9 5 Leucine Rich repeat LRR_4 PF12799.2 CCD27278.1 - 5.2e-06 25.9 31.9 0.0023 17.4 2.0 6.8 3 2 5 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCD27278.1 - 9.9e-05 22.0 22.7 0.079 12.7 2.1 5.4 3 1 2 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 CCD27278.1 - 0.00015 21.3 21.2 12 6.3 0.0 8.2 7 2 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 CCD27278.1 - 0.0076 16.2 11.6 53 4.6 0.5 6.8 7 0 0 7 7 7 0 Leucine rich repeat Myc_N PF01056.13 CCD27278.1 - 5.9 5.9 7.9 8.9 5.3 5.5 1.2 1 0 0 1 1 1 0 Myc amino-terminal region SWIB PF02201.13 CCD27279.1 - 1.5e-23 82.2 0.1 3.1e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 CCD27279.1 - 4.4e-10 39.1 0.0 1.3e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 DEK C terminal domain Rep_Org_C PF06926.6 CCD27279.1 - 0.12 12.5 1.6 6.3 6.9 0.0 2.7 3 0 0 3 3 3 0 Putative replisome organiser protein C-terminus Dsh_C PF12316.3 CCD27279.1 - 0.89 9.6 5.9 1.3 9.1 4.1 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal VPS11_C PF12451.3 CCD27281.1 - 2.4e-10 40.1 1.3 8.4e-10 38.3 0.1 2.4 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_5 PF14634.1 CCD27281.1 - 0.0013 18.4 9.0 0.0032 17.1 6.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCD27281.1 - 0.006 16.3 7.3 0.017 14.9 5.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCD27281.1 - 0.011 15.7 8.5 0.023 14.6 5.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCD27281.1 - 0.024 14.5 9.7 0.015 15.1 5.1 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CCD27281.1 - 0.07 12.7 8.6 0.16 11.6 5.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 CCD27281.1 - 0.13 12.0 8.3 0.23 11.1 4.6 2.2 2 0 0 2 2 2 0 PHD-finger zf-RING_UBOX PF13445.1 CCD27281.1 - 0.61 9.8 3.9 3.9 7.2 2.9 2.2 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 CCD27281.1 - 0.68 10.0 3.4 1.8 8.7 2.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger S10_plectin PF03501.10 CCD27282.1 - 6.9e-43 144.4 0.8 8e-43 144.2 0.5 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF505 PF04458.7 CCD27282.1 - 0.01 14.0 0.5 0.012 13.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF505) PadR PF03551.9 CCD27282.1 - 0.021 14.5 0.3 0.021 14.5 0.2 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family YjcQ PF09639.5 CCD27282.1 - 0.022 14.8 0.3 0.035 14.1 0.2 1.3 1 0 0 1 1 1 0 YjcQ protein HTH_45 PF14947.1 CCD27282.1 - 0.028 14.2 0.3 0.051 13.4 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DUF1975 PF09318.5 CCD27282.1 - 0.034 13.7 2.1 0.044 13.3 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1975) tRNA-synt_1c_C PF03950.13 CCD27282.1 - 0.09 12.4 0.1 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain DUF2977 PF11192.3 CCD27282.1 - 0.44 10.4 1.9 0.49 10.2 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2977) S1 PF00575.18 CCD27283.1 - 1.2e-60 201.4 28.3 2e-13 50.1 0.3 12.1 11 2 0 11 11 11 9 S1 RNA binding domain TPR_19 PF14559.1 CCD27283.1 - 3.5e-07 30.4 0.0 0.0064 16.8 0.0 3.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCD27283.1 - 4.5e-06 26.8 0.1 0.42 11.3 0.0 3.7 2 1 1 3 3 3 1 Tetratricopeptide repeat Suf PF05843.9 CCD27283.1 - 0.00047 19.9 5.7 0.002 17.9 3.6 5.1 3 2 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_16 PF13432.1 CCD27283.1 - 0.00063 20.3 0.0 0.37 11.5 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat EXOSC1 PF10447.4 CCD27283.1 - 0.016 15.1 11.3 0.33 10.9 0.1 7.0 6 3 1 7 7 7 0 Exosome component EXOSC1/CSL4 TPR_12 PF13424.1 CCD27283.1 - 0.03 14.2 0.0 23 5.0 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 CCD27283.1 - 0.043 12.8 4.0 0.2 10.6 0.9 2.7 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCD27283.1 - 0.062 12.9 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TRAM PF01938.15 CCD27283.1 - 0.36 10.6 6.2 1.2 8.9 0.0 4.9 6 0 0 6 6 6 0 TRAM domain RrnaAD PF00398.15 CCD27284.1 - 8.2e-54 182.3 0.2 9.7e-54 182.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 CCD27284.1 - 0.069 13.7 0.0 2.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain TAFII55_N PF04658.8 CCD27285.1 - 9.7e-53 177.9 0.1 9.7e-53 177.9 0.1 2.8 2 1 0 2 2 2 1 TAFII55 protein conserved region SNF2_N PF00176.18 CCD27286.1 - 2.2e-85 286.0 1.1 6.5e-85 284.5 0.8 1.9 1 0 0 1 1 1 1 SNF2 family N-terminal domain SnAC PF14619.1 CCD27286.1 - 3e-16 59.3 3.5 3e-16 59.3 2.4 4.7 5 0 0 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex Helicase_C PF00271.26 CCD27286.1 - 3.1e-16 58.9 0.1 2e-15 56.3 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 CCD27286.1 - 1.1e-15 57.3 1.1 3.9e-15 55.5 0.8 2.0 1 0 0 1 1 1 1 Bromodomain QLQ PF08880.6 CCD27286.1 - 2.4e-10 39.6 0.1 2.4e-10 39.6 0.1 2.5 2 0 0 2 2 2 1 QLQ MFS_1 PF07690.11 CCD27287.1 - 1e-07 31.0 31.8 4.4e-07 28.9 20.9 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily FSH1 PF03959.8 CCD27288.1 - 1.9e-58 197.4 0.0 2.1e-58 197.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CCD27288.1 - 6.4e-09 35.7 0.0 8.5e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCD27288.1 - 1.2e-07 31.9 0.0 0.0045 16.8 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCD27288.1 - 9.3e-05 21.9 0.0 0.00048 19.6 0.0 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Mre11_DNA_bind PF04152.9 CCD27289.1 - 8.8e-52 175.4 5.3 8.8e-52 175.4 3.7 3.4 2 1 1 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CCD27289.1 - 5.2e-23 81.4 2.5 5.2e-23 81.4 1.7 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCD27289.1 - 0.001 18.9 0.0 0.0041 16.9 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4484 PF14831.1 CCD27289.1 - 7.1 6.6 15.8 5.8 6.9 6.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) AMMECR1 PF01871.12 CCD27290.1 - 1.5e-33 115.3 0.0 1.9e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 adh_short PF00106.20 CCD27291.1 - 3.2e-29 101.9 0.0 4.1e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCD27291.1 - 1.4e-07 31.3 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCD27291.1 - 0.011 15.4 0.3 0.022 14.5 0.2 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 CCD27291.1 - 0.016 14.0 0.1 0.03 13.2 0.1 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein AAA_14 PF13173.1 CCD27291.1 - 0.13 12.1 0.1 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain TRAPPC10 PF12584.3 CCD27293.1 - 1e-08 34.8 0.0 3.3e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 MYCBPAP PF14646.1 CCD27293.1 - 0.0084 14.8 0.2 0.023 13.4 0.1 1.7 2 0 0 2 2 2 1 MYCBP-associated protein family Foie-gras_1 PF11817.3 CCD27293.1 - 0.017 14.5 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 Foie gras liver health family 1 Pkinase PF00069.20 CCD27294.1 - 4.7e-42 143.9 0.5 1.3e-22 80.2 0.4 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCD27294.1 - 2.1e-10 40.1 1.6 9.2e-08 31.4 0.2 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_72 PF03198.9 CCD27295.1 - 3.2e-124 413.9 5.7 4.5e-124 413.5 3.9 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 CCD27295.1 - 3e-05 23.0 0.0 4.9e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 CCD27295.1 - 0.0061 15.8 0.2 0.017 14.3 0.1 1.8 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SUKH-3 PF14433.1 CCD27295.1 - 0.13 12.0 0.0 0.37 10.5 0.0 1.7 1 1 0 1 1 1 0 SUKH-3 immunity protein Tmemb_cc2 PF10267.4 CCD27295.1 - 1.5 7.3 7.1 2.2 6.7 4.9 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.4 CCD27295.1 - 8.3 4.5 11.4 12 4.0 7.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Myb_DNA-binding PF00249.26 CCD27296.1 - 9.9e-22 76.7 0.9 2.4e-11 43.4 0.4 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCD27296.1 - 7e-20 70.8 3.5 7.1e-13 48.4 0.5 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 CCD27296.1 - 0.022 14.6 0.0 0.075 12.9 0.0 1.9 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Abhydrolase_1 PF00561.15 CCD27297.1 - 6.3e-11 42.2 0.0 2e-10 40.6 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCD27297.1 - 1.1e-09 38.5 0.0 1.8e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCD27297.1 - 1.4e-05 24.8 0.0 3.8e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CCD27297.1 - 0.0002 20.5 0.3 0.00061 18.9 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Cutinase PF01083.17 CCD27297.1 - 0.00053 19.7 0.0 0.00079 19.2 0.0 1.2 1 0 0 1 1 1 1 Cutinase DUF4375 PF14300.1 CCD27297.1 - 0.009 15.9 0.0 0.19 11.7 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4375) Lipase_3 PF01764.20 CCD27297.1 - 0.037 13.6 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) FliS PF02561.9 CCD27298.1 - 0.049 13.4 1.7 0.26 11.1 1.2 2.3 1 0 0 1 1 1 0 Flagellar protein FliS CTD_bind PF04818.8 CCD27298.1 - 0.063 13.5 1.5 0.16 12.2 0.4 2.3 2 0 0 2 2 2 0 RNA polymerase II-binding domain. Tubulin_3 PF14881.1 CCD27299.1 - 1.2e-26 93.2 0.2 3.6e-26 91.7 0.0 1.8 2 0 0 2 2 2 1 Tubulin domain Misat_Tub_SegII PF10644.4 CCD27299.1 - 2.9e-18 65.9 0.3 7.4e-18 64.6 0.2 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 CCD27299.1 - 0.011 15.5 0.0 0.036 13.8 0.0 1.8 2 0 0 2 2 2 0 Tubulin/FtsZ family, GTPase domain Tox-REase-7 PF15649.1 CCD27299.1 - 0.044 13.9 0.1 0.1 12.7 0.1 1.6 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 DIT1_PvcA PF05141.7 CCD27299.1 - 0.052 12.8 0.9 0.085 12.1 0.6 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF2142 PF09913.4 CCD27299.1 - 0.59 8.7 2.3 0.37 9.3 0.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) CAP_GLY PF01302.20 CCD27301.1 - 3.1e-19 68.4 0.1 5e-19 67.7 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain CCD PF07860.6 CCD27301.1 - 0.081 12.3 0.4 0.23 10.9 0.1 1.9 2 0 0 2 2 2 0 WisP family C-Terminal Region EF-hand_1 PF00036.27 CCD27302.1 - 1.4e-26 89.7 13.1 2.9e-07 29.2 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCD27302.1 - 2.3e-24 85.3 7.4 2.6e-13 49.9 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCD27302.1 - 1.4e-21 74.3 8.7 5.8e-07 28.8 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CCD27302.1 - 7.9e-18 63.8 11.5 4.7e-11 42.1 0.4 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CCD27302.1 - 3.2e-17 61.0 7.5 4.4e-05 22.6 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 CCD27302.1 - 3.3e-06 26.7 1.9 0.001 18.7 0.1 2.4 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CCD27302.1 - 3.4e-06 26.8 0.1 0.034 14.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CCD27302.1 - 0.0057 16.6 0.2 0.98 9.4 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region VCBS PF13517.1 CCD27302.1 - 0.0075 16.5 0.2 0.62 10.4 0.0 2.4 2 0 0 2 2 2 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Caleosin PF05042.8 CCD27302.1 - 0.011 15.2 0.0 0.064 12.7 0.0 2.1 2 1 1 3 3 3 0 Caleosin related protein Mor PF08765.6 CCD27302.1 - 0.11 12.3 0.0 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 Mor transcription activator family Dockerin_1 PF00404.13 CCD27302.1 - 3.5 7.5 5.5 10 6.0 0.1 2.9 2 0 0 2 2 2 0 Dockerin type I repeat UbiA PF01040.13 CCD27304.1 - 4.4e-25 88.3 10.9 6e-25 87.9 7.6 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family MitMem_reg PF13012.1 CCD27305.1 - 2.9e-39 133.7 1.4 2.9e-39 133.7 1.0 2.2 3 0 0 3 3 3 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CCD27305.1 - 1.7e-28 98.6 3.4 2.7e-28 97.9 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease KilA-N PF04383.8 CCD27305.1 - 1.9 8.1 7.8 1.8 8.2 0.0 2.4 2 0 0 2 2 2 0 KilA-N domain Hus1 PF04005.7 CCD27305.1 - 2.2 7.1 10.1 0.82 8.5 3.8 2.3 3 0 0 3 3 3 0 Hus1-like protein Pkinase PF00069.20 CCD27306.1 - 3.3e-51 173.9 7.0 3.3e-51 173.9 4.8 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD27306.1 - 1.2e-20 73.7 4.1 1.7e-20 73.1 1.2 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD27306.1 - 2.9e-05 23.1 0.1 0.00021 20.3 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 CCD27306.1 - 0.046 13.4 0.0 0.091 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family GHMP_kinases_N PF00288.21 CCD27307.1 - 3.5e-21 75.0 0.0 8.2e-21 73.8 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCD27307.1 - 2.5e-08 34.0 0.4 8.4e-08 32.3 0.0 2.1 2 1 1 3 3 3 1 GHMP kinases C terminal Tub_2 PF04525.7 CCD27308.1 - 0.094 12.1 0.0 0.094 12.1 0.0 1.0 1 0 0 1 1 1 0 Tubby C 2 PIGA PF08288.7 CCD27309.1 - 1.1e-42 144.3 1.6 3.5e-42 142.6 1.1 2.0 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CCD27309.1 - 5.2e-30 104.1 0.0 9.1e-30 103.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCD27309.1 - 1.2e-20 73.9 0.6 2.1e-20 73.1 0.4 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CCD27309.1 - 8.9e-15 55.1 0.0 2.1e-14 53.9 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CCD27309.1 - 5.3e-12 46.0 0.0 2.1e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CCD27309.1 - 4.3e-07 29.8 0.6 8.1e-07 28.9 0.4 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 CCD27309.1 - 0.0033 17.6 0.0 0.015 15.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 CCD27309.1 - 0.024 14.1 0.1 0.15 11.4 0.0 2.0 1 1 1 2 2 2 0 Starch synthase catalytic domain DUF4205 PF13898.1 CCD27309.1 - 0.091 11.4 0.0 0.18 10.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4205) TFR_dimer PF04253.10 CCD27310.1 - 7.8e-28 96.5 0.0 1.5e-27 95.6 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CCD27310.1 - 2.6e-08 33.4 0.0 1.1e-06 28.2 0.0 2.7 3 0 0 3 3 3 1 PA domain Peptidase_M28 PF04389.12 CCD27310.1 - 5.9e-05 22.8 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Cyt-b5 PF00173.23 CCD27311.1 - 1.2e-12 47.3 0.0 1.8e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TAP_C PF03943.8 CCD27313.1 - 9.2e-14 50.5 0.0 2.1e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 CCD27313.1 - 1.8e-06 27.4 9.6 0.00014 21.4 3.5 3.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 CCD27313.1 - 3.9e-06 26.5 1.2 7.5e-06 25.6 0.8 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.1 CCD27313.1 - 0.008 16.1 7.9 0.95 9.7 0.8 4.2 2 1 1 3 3 3 2 Leucine Rich repeat LRR_1 PF00560.28 CCD27313.1 - 8 6.9 13.0 35 4.9 0.2 5.1 4 1 0 5 5 5 0 Leucine Rich Repeat DnaJ PF00226.26 CCD27314.1 - 1.1e-19 69.8 0.8 2.5e-19 68.7 0.6 1.6 1 0 0 1 1 1 1 DnaJ domain Sec63 PF02889.11 CCD27314.1 - 4.9e-18 65.4 0.3 4e-15 55.8 0.0 2.4 1 1 0 2 2 2 2 Sec63 Brl domain Ins_allergen_rp PF06757.8 CCD27314.1 - 0.0029 17.0 0.0 0.006 16.0 0.0 1.5 1 0 0 1 1 1 1 Insect allergen related repeat, nitrile-specifier detoxification RAI1 PF08652.6 CCD27314.1 - 0.047 13.4 0.1 10 6.0 0.0 2.6 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease Acetyltransf_1 PF00583.19 CCD27315.1 - 7e-11 42.0 0.0 1e-10 41.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCD27315.1 - 1.6e-05 24.9 0.2 2.4e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCD27315.1 - 0.00033 20.6 0.1 0.00038 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCD27315.1 - 0.0031 17.2 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCD27315.1 - 0.0039 17.2 0.0 0.005 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NPL4 PF05021.10 CCD27316.1 - 0.0093 15.1 1.2 0.25 10.4 0.2 2.2 2 0 0 2 2 2 2 NPL4 family DUF1767 PF08585.7 CCD27316.1 - 0.015 15.5 1.8 3 8.1 0.1 3.3 2 1 2 4 4 4 0 Domain of unknown function (DUF1767) SpoIID PF08486.5 CCD27316.1 - 0.12 12.6 0.4 1.6 9.0 0.0 3.0 3 1 0 3 3 3 0 Stage II sporulation protein DNA_pol_B PF00136.16 CCD27317.1 - 1.5e-95 320.7 0.9 2.3e-95 320.1 0.6 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CCD27317.1 - 9.3e-21 74.0 6.4 1.4e-10 40.5 1.1 3.0 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CCD27317.1 - 7.7e-12 45.0 8.0 1.8e-11 43.8 5.6 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta HypA PF01155.14 CCD27317.1 - 0.29 10.8 3.6 0.39 10.4 0.4 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 CCD27317.1 - 1.2 8.9 5.4 5 7.0 3.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon AF0941-like PF14591.1 CCD27318.1 - 0.0027 17.7 1.5 0.0042 17.1 0.7 1.6 1 1 0 1 1 1 1 AF0941-like SET PF00856.23 CCD27319.1 - 1.3e-08 35.3 0.1 1e-07 32.4 0.0 2.1 2 0 0 2 2 2 1 SET domain YHS PF04945.8 CCD27319.1 - 0.011 15.5 0.1 0.035 13.9 0.1 1.8 1 0 0 1 1 1 0 YHS domain HATPase_c_3 PF13589.1 CCD27320.1 - 1.4e-11 44.1 0.2 2.7e-11 43.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCD27320.1 - 3.4e-08 33.1 0.1 9.5e-08 31.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 CCD27320.1 - 0.00018 21.1 0.0 0.00057 19.5 0.0 1.8 2 0 0 2 2 2 1 MutL C terminal dimerisation domain NSP2-B_epitope PF14757.1 CCD27321.1 - 0.062 12.7 4.1 0.059 12.8 2.2 1.4 1 1 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Cytochrome-c551 PF10643.4 CCD27321.1 - 0.45 9.7 3.4 0.74 9.0 2.4 1.6 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 DUF3661 PF12400.3 CCD27322.1 - 3.5e-44 150.0 8.0 3.5e-44 150.0 5.6 2.1 3 1 0 3 3 3 1 Vaculolar membrane protein Colicin_V PF02674.11 CCD27322.1 - 0.053 13.3 1.8 0.15 11.9 0.9 2.0 2 0 0 2 2 2 0 Colicin V production protein Pet20 PF08692.5 CCD27323.1 - 5.7e-22 78.1 6.9 8.5e-11 41.9 0.1 3.2 2 1 1 3 3 3 2 Mitochondrial protein Pet20 Methyltransf_15 PF09445.5 CCD27325.1 - 8e-59 197.8 1.5 8.7e-59 197.7 0.1 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 CCD27325.1 - 1.8e-07 30.9 0.0 3.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_31 PF13847.1 CCD27325.1 - 1.8e-06 27.6 0.1 4.1e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCD27325.1 - 2.6e-06 27.9 0.0 4.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCD27325.1 - 4.7e-06 26.6 0.0 7.2e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CCD27325.1 - 0.0026 17.1 0.0 0.0088 15.4 0.0 1.8 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 CCD27325.1 - 0.0054 17.0 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Mon1 PF03164.9 CCD27327.1 - 0.063 11.8 0.3 0.071 11.7 0.2 1.1 1 0 0 1 1 1 0 Trafficking protein Mon1 Pkinase PF00069.20 CCD27328.1 - 3.8e-69 232.7 0.0 6.3e-69 232.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD27328.1 - 6.2e-31 107.3 0.0 9.1e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCD27328.1 - 7.9e-10 39.1 0.4 2.7e-09 37.3 0.3 2.0 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCD27328.1 - 0.0049 15.8 0.0 0.011 14.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCD27328.1 - 0.086 11.9 0.1 0.16 11.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCD27328.1 - 0.21 11.3 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRN3 PF05327.6 CCD27329.1 - 2.7e-174 580.4 18.2 9.3e-174 578.6 12.6 1.7 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.9 CCD27329.1 - 0.0017 16.4 9.1 0.0025 15.9 6.3 1.2 1 0 0 1 1 1 1 CDC45-like protein DUF1539 PF07560.6 CCD27329.1 - 0.21 11.4 2.7 0.56 10.0 0.1 2.9 2 2 1 3 3 3 0 Domain of Unknown Function (DUF1539) DUF1510 PF07423.6 CCD27329.1 - 0.25 10.7 12.9 0.4 10.0 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2457 PF10446.4 CCD27329.1 - 0.99 8.0 24.0 1.5 7.4 16.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 CCD27329.1 - 2.8 6.2 25.9 4 5.7 18.0 1.1 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 CCD27329.1 - 5.4 5.9 18.8 7.4 5.5 13.0 1.1 1 0 0 1 1 1 0 BUD22 RP-C_C PF11800.3 CCD27329.1 - 7.9 6.1 6.1 8.5 6.0 3.5 1.5 2 0 0 2 2 2 0 Replication protein C C-terminal region SDA1 PF05285.7 CCD27329.1 - 7.9 5.6 25.6 12 5.0 17.7 1.2 1 0 0 1 1 1 0 SDA1 Astro_capsid PF03115.9 CCD27329.1 - 8.5 4.4 6.3 12 4.0 4.4 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor BTV_NS2 PF04514.7 CCD27329.1 - 9.2 5.0 13.2 15 4.3 9.2 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 SPRY PF00622.23 CCD27330.1 - 1.7e-13 50.7 0.0 3.4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 SPRY domain DUF1825 PF08855.5 CCD27330.1 - 0.19 11.7 1.8 2 8.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) SRP9-21 PF05486.7 CCD27331.1 - 7.2e-23 80.1 0.3 1.2e-22 79.4 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) MMTV_SAg PF01054.12 CCD27331.1 - 0.077 11.8 0.3 0.088 11.6 0.2 1.2 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen WD40 PF00400.27 CCD27332.1 - 1.3e-21 75.5 12.5 1.1e-06 28.2 0.1 5.7 7 0 0 7 7 7 3 WD domain, G-beta repeat N2227 PF07942.7 CCD27334.1 - 1.6e-56 191.2 0.7 2.8e-56 190.4 0.5 1.4 1 0 0 1 1 1 1 N2227-like protein FANCI_S2 PF14676.1 CCD27334.1 - 0.061 13.2 0.1 0.13 12.1 0.1 1.6 1 0 0 1 1 1 0 FANCI solenoid 2 Neurochondrin PF05536.6 CCD27334.1 - 0.066 11.5 0.1 0.11 10.8 0.0 1.2 1 0 0 1 1 1 0 Neurochondrin Peptidase_A21 PF03566.8 CCD27334.1 - 0.09 10.8 0.2 0.21 9.6 0.0 1.6 2 0 0 2 2 2 0 Peptidase family A21 SapB_1 PF05184.10 CCD27334.1 - 0.88 9.4 5.2 1.5 8.7 0.0 3.5 4 1 1 5 5 5 0 Saposin-like type B, region 1 PIGA PF08288.7 CCD27335.1 - 4.3e-46 155.2 2.6 1.7e-45 153.3 1.8 2.1 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CCD27335.1 - 4.7e-32 110.7 0.0 7.8e-32 110.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCD27335.1 - 9.9e-19 67.7 0.5 1.7e-18 66.9 0.4 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CCD27335.1 - 2e-13 50.7 0.0 2.8e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CCD27335.1 - 1.5e-12 47.8 0.0 3.5e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CCD27335.1 - 1.2e-06 28.4 0.8 2.6e-06 27.3 0.6 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 CCD27335.1 - 0.0045 17.2 0.2 0.04 14.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 CCD27335.1 - 0.039 13.4 0.1 0.27 10.6 0.0 2.2 1 1 1 2 2 2 0 Starch synthase catalytic domain DUF3437 PF11919.3 CCD27335.1 - 0.046 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) TFR_dimer PF04253.10 CCD27336.1 - 4.4e-37 126.4 0.2 1.2e-36 125.0 0.0 1.8 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CCD27336.1 - 3.3e-08 33.1 0.1 8.8e-07 28.5 0.0 2.4 2 0 0 2 2 2 1 PA domain Peptidase_M28 PF04389.12 CCD27336.1 - 0.00047 19.9 0.0 0.0012 18.6 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Nicastrin PF05450.10 CCD27336.1 - 0.039 13.1 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Tox-PLDMTX PF15645.1 CCD27336.1 - 0.046 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold Mito_carr PF00153.22 CCD27337.1 - 2.2e-59 197.1 4.7 1.7e-20 72.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Vma12 PF11712.3 CCD27338.1 - 2.9e-32 111.3 0.2 4.2e-32 110.7 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase MscS_TM PF12794.2 CCD27338.1 - 0.008 14.8 0.5 0.015 13.8 0.0 1.6 1 1 1 2 2 2 1 Mechanosensitive ion channel inner membrane domain 1 ATG22 PF11700.3 CCD27338.1 - 0.031 12.7 0.1 0.042 12.3 0.1 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like eIF-5a PF01287.15 CCD27338.1 - 0.098 12.6 1.9 0.15 12.0 0.3 2.1 2 1 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold SseC PF04888.7 CCD27338.1 - 0.15 11.3 0.3 0.23 10.7 0.0 1.4 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family CHD5 PF04420.9 CCD27338.1 - 1.6 8.4 5.6 1 9.0 0.3 2.6 2 1 1 3 3 3 0 CHD5-like protein Pkinase PF00069.20 CCD27339.1 - 2.3e-56 190.8 0.0 3.3e-56 190.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD27339.1 - 2.5e-22 79.1 0.0 3.9e-21 75.2 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CCD27339.1 - 0.053 12.3 0.9 0.088 11.5 0.6 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 CCD27339.1 - 0.12 11.3 0.0 0.36 9.7 0.0 1.7 1 1 0 1 1 1 0 Kinase-like AP_endonuc_2 PF01261.19 CCD27340.1 - 1e-30 106.6 0.0 1.6e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel BAF1_ABF1 PF04684.8 CCD27341.1 - 7.8e-65 219.6 10.6 2.1e-64 218.1 7.3 1.8 1 1 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.10 CCD27341.1 - 3.5e-05 23.3 1.8 0.00085 18.8 0.4 2.6 2 0 0 2 2 2 1 MuDR family transposase DUF382 PF04037.8 CCD27341.1 - 0.07 12.9 1.5 0.16 11.7 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF382) UPF0167 PF03691.9 CCD27341.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) KTI12 PF08433.5 CCD27342.1 - 8.5e-93 310.4 2.8 9.8e-93 310.2 1.9 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 CCD27342.1 - 1e-07 32.3 2.1 1.8e-07 31.4 0.0 2.3 2 2 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCD27342.1 - 2e-07 31.8 0.0 5.7e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCD27342.1 - 8.3e-07 28.9 0.0 2.8e-06 27.2 0.0 1.8 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.15 CCD27342.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.24 CCD27342.1 - 0.00066 19.8 0.2 0.002 18.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCD27342.1 - 0.00068 19.7 0.1 0.0033 17.5 0.0 2.2 3 0 0 3 3 3 1 AAA domain Elong_Iki1 PF10483.4 CCD27342.1 - 0.0062 15.9 0.4 0.0062 15.9 0.2 1.7 2 0 0 2 2 2 1 Elongator subunit Iki1 CPT PF07931.7 CCD27342.1 - 0.019 14.5 0.0 0.059 12.9 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.1 CCD27342.1 - 0.029 14.3 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 CCD27342.1 - 0.034 14.3 0.2 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.16 CCD27342.1 - 0.04 13.0 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CCD27342.1 - 0.055 13.4 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCD27342.1 - 0.086 12.7 1.3 0.16 11.8 0.1 2.1 2 2 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CCD27342.1 - 0.1 12.2 0.7 0.66 9.6 0.0 2.4 2 1 1 3 3 3 0 NTPase Hap4_Hap_bind PF10297.4 CCD27343.1 - 0.69 9.8 21.1 0.028 14.3 9.4 2.6 2 1 0 2 2 2 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Drc1-Sld2 PF11719.3 CCD27344.1 - 4.4e-48 164.4 34.9 5.3e-48 164.1 24.2 1.1 1 0 0 1 1 1 1 DNA replication and checkpoint protein NAD_binding_10 PF13460.1 CCD27345.1 - 3.9e-18 66.1 0.0 5e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCD27345.1 - 0.00056 18.7 0.4 0.00085 18.1 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCD27345.1 - 0.0029 17.0 0.0 0.0068 15.8 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CCD27345.1 - 0.089 13.1 0.1 0.19 12.0 0.1 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain cobW PF02492.14 CCD27346.1 - 4e-42 143.6 0.6 4e-42 143.6 0.4 1.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 CCD27346.1 - 0.00035 20.2 0.0 0.00067 19.3 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 CCD27346.1 - 0.00091 18.7 0.8 0.56 9.6 0.0 2.6 3 0 0 3 3 3 2 Elongation factor Tu GTP binding domain MobB PF03205.9 CCD27346.1 - 0.0015 18.2 0.4 0.0097 15.6 0.0 2.5 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 CCD27346.1 - 0.0021 17.9 0.5 0.0081 16.1 0.1 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 CCD27346.1 - 0.0032 16.9 0.1 0.009 15.5 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CCD27346.1 - 0.0057 16.3 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 CCD27346.1 - 0.014 15.7 4.4 0.022 15.0 0.5 2.8 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CCD27346.1 - 0.019 14.8 0.1 0.25 11.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CCD27346.1 - 0.022 14.4 0.0 0.057 13.1 0.0 1.7 1 0 0 1 1 1 0 NTPase AAA_10 PF12846.2 CCD27346.1 - 0.024 14.0 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 CCD27346.1 - 0.03 14.6 0.0 0.03 14.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CCD27346.1 - 0.07 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 CCD27346.1 - 0.084 12.5 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain ArgK PF03308.11 CCD27346.1 - 0.11 11.2 1.1 0.86 8.3 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_33 PF13671.1 CCD27346.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pro_isomerase PF00160.16 CCD27347.1 - 1.4e-22 80.6 0.1 2e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Phos_pyr_kin PF08543.7 CCD27348.1 - 8.6e-08 31.6 0.0 1.4e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CCD27348.1 - 1.1e-05 24.7 0.0 8.4e-05 21.8 0.0 2.2 2 1 0 2 2 2 1 pfkB family carbohydrate kinase WD40 PF00400.27 CCD27349.1 - 5.1e-06 26.1 0.3 0.00072 19.3 0.2 3.6 3 0 0 3 3 3 1 WD domain, G-beta repeat HMA PF00403.21 CCD27349.1 - 0.025 14.7 1.0 16 5.7 0.0 3.4 3 0 0 3 3 3 0 Heavy-metal-associated domain Fork_head PF00250.13 CCD27350.1 - 7.5e-30 102.8 1.1 7.5e-30 102.8 0.7 2.1 2 1 0 2 2 2 1 Fork head domain CENP-B_dimeris PF09026.5 CCD27351.1 - 0.8 9.9 9.5 1.7 8.9 6.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain AF1Q PF15017.1 CCD27351.1 - 3.1 7.7 10.6 0.71 9.8 4.8 2.0 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Ribosomal_L9_N PF01281.14 CCD27352.1 - 2.9e-05 23.1 0.1 0.00015 20.9 0.0 2.0 1 1 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Peptidase_M76 PF09768.4 CCD27353.1 - 4.2e-74 247.7 3.7 5.1e-74 247.4 2.5 1.1 1 0 0 1 1 1 1 Peptidase M76 family DUF2256 PF10013.4 CCD27353.1 - 4 7.2 7.2 7.4 6.4 0.1 3.5 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) MBOAT PF03062.14 CCD27354.1 - 1.1e-57 195.6 45.4 6.4e-57 193.1 31.5 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CCD27354.1 - 0.0051 16.8 6.2 0.015 15.3 4.3 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family HIG_1_N PF04588.8 CCD27355.1 - 9.2e-06 25.3 1.2 2.1e-05 24.1 0.8 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Tim17 PF02466.14 CCD27357.1 - 5.2e-30 104.1 2.4 7e-30 103.7 1.7 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Dus PF01207.12 CCD27359.1 - 5.8e-47 160.0 0.0 1.2e-46 158.9 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) SLA_LP_auto_ag PF05889.8 CCD27359.1 - 0.0068 14.9 0.0 0.0097 14.4 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) ThiC PF01964.13 CCD27359.1 - 0.017 13.6 0.1 0.55 8.6 0.0 2.1 1 1 1 2 2 2 0 ThiC family COX5A PF02284.11 CCD27359.1 - 0.035 14.0 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va TMP-TENI PF02581.12 CCD27359.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI SPX PF03105.14 CCD27360.1 - 3.8e-50 171.2 5.0 2.8e-49 168.3 0.1 2.1 2 0 0 2 2 2 2 SPX domain Na_sulph_symp PF00939.14 CCD27360.1 - 2.6e-20 72.7 40.3 3.6e-20 72.3 28.0 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CCD27360.1 - 2.2e-13 49.5 43.5 5.3e-11 41.6 14.4 2.1 1 1 1 2 2 2 2 Citrate transporter PRK PF00485.13 CCD27361.1 - 5.9e-62 208.6 0.0 9.5e-62 208.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 CCD27361.1 - 9.4e-33 113.1 0.1 1.3e-32 112.6 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 CCD27361.1 - 3e-10 40.9 0.1 7e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCD27361.1 - 1.4e-07 31.8 0.1 8.1e-07 29.4 0.0 2.3 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 CCD27361.1 - 0.0024 17.0 0.0 0.0041 16.2 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin CPT PF07931.7 CCD27361.1 - 0.0077 15.8 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 CCD27361.1 - 0.042 13.7 0.1 0.34 10.7 0.0 2.3 3 0 0 3 3 3 0 AAA domain OB_NTP_bind PF07717.11 CCD27362.1 - 1.4e-19 69.9 0.1 7.7e-19 67.6 0.0 2.3 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CCD27362.1 - 5.3e-17 61.7 0.0 1.9e-16 59.9 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCD27362.1 - 4.9e-14 51.9 0.0 1.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCD27362.1 - 7.1e-08 32.1 1.8 2e-07 30.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCD27362.1 - 0.00035 20.7 0.5 0.0014 18.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain T2SE PF00437.15 CCD27362.1 - 0.0008 18.3 0.0 0.0031 16.4 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 CCD27362.1 - 0.0099 15.7 4.9 0.21 11.4 0.7 3.9 3 1 0 3 3 3 1 AAA domain Flavi_DEAD PF07652.9 CCD27362.1 - 0.034 13.9 0.0 0.067 12.9 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_25 PF13481.1 CCD27362.1 - 0.082 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCD27362.1 - 0.12 12.1 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 CCD27362.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CCD27362.1 - 0.2 11.1 0.3 0.6 9.6 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.22 CCD27362.1 - 0.24 11.7 0.0 0.24 11.7 0.0 2.5 2 1 0 2 2 1 0 ABC transporter Glyoxalase PF00903.20 CCD27363.1 - 3.7e-37 127.1 0.1 8.5e-20 71.0 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CCD27363.1 - 4.9e-30 104.3 0.0 1.6e-14 54.4 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CCD27363.1 - 3.7e-16 59.0 0.0 2.7e-07 30.5 0.0 3.7 1 1 2 3 3 3 3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 CCD27363.1 - 9.1e-05 22.4 0.0 0.94 9.3 0.0 3.8 2 2 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.1 CCD27363.1 - 0.00022 20.9 0.2 0.22 11.1 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal DUF3081 PF11280.3 CCD27363.1 - 0.11 12.0 0.0 3.5 7.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3081) Med9 PF07544.8 CCD27364.1 - 1.7e-23 82.1 0.2 3.3e-23 81.2 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF4200 PF13863.1 CCD27364.1 - 0.03 14.2 1.7 0.043 13.7 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2383 PF09537.5 CCD27364.1 - 0.042 14.0 0.3 0.06 13.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2383) NUC129 PF08157.6 CCD27364.1 - 0.063 13.1 1.6 3.5 7.6 0.1 2.7 2 1 0 2 2 2 0 NUC129 domain RBFA PF02033.13 CCD27364.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.7 1 1 0 1 1 1 0 Ribosome-binding factor A BCNT PF07572.7 CCD27364.1 - 0.25 11.2 1.7 0.45 10.4 0.8 1.7 1 1 1 2 2 2 0 Bucentaur or craniofacial development Macoilin PF09726.4 CCD27364.1 - 0.33 9.1 7.1 0.36 9.0 4.9 1.0 1 0 0 1 1 1 0 Transmembrane protein Syntaxin PF00804.20 CCD27364.1 - 1 9.5 4.6 1.6 8.9 2.4 2.0 1 1 1 2 2 2 0 Syntaxin Whi5 PF08528.6 CCD27365.1 - 4.2e-10 38.9 1.1 1e-09 37.7 0.8 1.7 1 0 0 1 1 1 1 Whi5 like DNA_primase_lrg PF04104.9 CCD27366.1 - 1.3e-84 283.5 0.4 2e-84 282.9 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit KilA-N PF04383.8 CCD27367.1 - 5.2e-06 26.0 0.1 5.4e-05 22.7 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Spc42p PF11544.3 CCD27368.1 - 3e-10 39.8 10.5 3e-10 39.8 7.3 2.9 3 0 0 3 3 3 1 Spindle pole body component Spc42p Snf7 PF03357.16 CCD27369.1 - 1.2e-31 109.4 22.0 1.2e-31 109.4 15.3 2.0 2 0 0 2 2 2 1 Snf7 MutS_III PF05192.13 CCD27369.1 - 0.0018 18.1 6.2 0.0029 17.4 4.3 1.4 1 1 0 1 1 1 1 MutS domain III PAS_7 PF12860.2 CCD27369.1 - 0.0083 16.1 3.3 0.96 9.4 0.0 3.0 1 1 2 3 3 3 2 PAS fold Apc13p PF05839.6 CCD27369.1 - 0.17 11.8 4.6 0.47 10.4 3.2 1.8 1 0 0 1 1 1 0 Apc13p protein TAF8_C PF10406.4 CCD27369.1 - 0.22 11.6 1.8 0.38 10.8 0.1 2.4 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term DUF4206 PF13901.1 CCD27369.1 - 0.56 9.7 2.7 0.69 9.4 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) MbeB_N PF04837.7 CCD27369.1 - 0.64 10.1 7.9 8.7 6.5 1.2 2.8 2 0 0 2 2 2 0 MbeB-like, N-term conserved region Rota_NS53 PF00981.12 CCD27369.1 - 2.3 6.7 8.4 0.91 8.0 3.7 1.7 1 1 1 2 2 2 0 Rotavirus RNA-binding Protein 53 (NS53) DUF2422 PF10337.4 CCD27369.1 - 9 4.9 9.2 14 4.3 6.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2422) Lung_7-TM_R PF06814.8 CCD27370.1 - 2.2e-82 276.3 20.6 3.1e-82 275.8 14.3 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor Zn_clus PF00172.13 CCD27371.1 - 1.7e-08 34.2 13.2 1.7e-08 34.2 9.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.1 CCD27372.1 - 9.6e-11 41.3 5.3 2e-10 40.3 3.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCD27372.1 - 1.6e-08 34.5 3.0 2.9e-08 33.6 2.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CCD27372.1 - 4.6e-08 32.6 3.5 7.8e-08 31.9 2.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCD27372.1 - 8.9e-06 25.2 3.4 1.8e-05 24.2 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCD27372.1 - 7e-05 22.4 5.8 0.00014 21.4 4.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCD27372.1 - 7.1e-05 22.7 2.3 7.1e-05 22.7 1.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCD27372.1 - 0.0015 18.3 1.3 0.0031 17.3 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 CCD27372.1 - 0.016 15.1 2.5 0.022 14.7 1.1 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain Cys_rich_CPXG PF14255.1 CCD27372.1 - 0.026 14.3 1.7 0.033 14.0 0.1 2.0 2 0 0 2 2 2 0 Cysteine-rich CPXCG zf-RING_UBOX PF13445.1 CCD27372.1 - 0.031 14.0 1.3 0.086 12.5 0.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger SseB_C PF14581.1 CCD27372.1 - 0.061 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 SseB protein C-terminal domain zf-RING_6 PF14835.1 CCD27372.1 - 0.072 12.8 1.3 0.13 12.0 0.2 1.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Baculo_RING PF05883.6 CCD27372.1 - 0.98 9.2 4.7 0.21 11.4 0.5 1.9 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain HAD_2 PF13419.1 CCD27373.1 - 1.9e-16 60.7 0.0 2.3e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCD27373.1 - 9.5e-07 29.4 0.0 1.1e-06 29.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 CCD27373.1 - 0.03 14.2 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CCD27373.1 - 0.045 13.9 0.0 0.049 13.8 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pribosyl_synth PF14572.1 CCD27374.1 - 4.1e-41 140.7 2.1 2.9e-35 121.6 1.1 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CCD27374.1 - 6.7e-37 125.7 0.3 4.4e-36 123.1 0.0 2.2 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CCD27374.1 - 1.2e-11 44.3 0.8 6.3e-11 42.0 0.7 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Chlorosome_CsmC PF11098.3 CCD27374.1 - 0.039 13.6 1.1 0.084 12.5 0.8 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C UPRTase PF14681.1 CCD27374.1 - 0.041 13.0 0.1 0.066 12.4 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase HycA_repressor PF11046.3 CCD27375.1 - 0.015 15.2 0.2 0.045 13.6 0.2 1.8 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons Phage_int_SAM_1 PF02899.12 CCD27375.1 - 0.097 12.8 0.6 9.1 6.5 0.0 3.9 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain HMG_box PF00505.14 CCD27376.1 - 5.1e-33 113.1 16.0 6.3e-18 64.8 0.5 3.7 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CCD27376.1 - 1.6e-15 57.1 4.3 1.9e-10 40.9 0.3 4.1 3 1 0 3 3 3 2 HMG-box domain CHDNT PF08073.7 CCD27376.1 - 1.9e-07 30.6 0.1 0.00042 19.9 0.0 2.6 2 0 0 2 2 2 2 CHDNT (NUC034) domain zf-C2H2 PF00096.21 CCD27377.1 - 6.2e-05 23.0 12.2 0.00066 19.8 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCD27377.1 - 0.00016 21.8 11.5 0.00067 19.8 1.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 CCD27377.1 - 0.00051 20.1 3.1 0.0012 18.9 2.1 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CCD27377.1 - 2.5 8.2 8.9 9.4 6.4 0.1 3.2 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Malic_M PF03949.10 CCD27378.1 - 7.7e-77 258.2 0.0 1.2e-76 257.6 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CCD27378.1 - 6.4e-63 211.6 0.0 1.2e-62 210.7 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.15 CCD27378.1 - 0.00032 20.8 0.6 0.1 12.7 0.0 3.6 3 1 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase TFIIE_alpha PF02002.12 CCD27379.1 - 2.2e-34 117.1 0.0 2.2e-34 117.1 0.0 2.6 3 0 0 3 3 3 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 CCD27379.1 - 1.4e-10 40.2 0.4 4.3e-10 38.7 0.3 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding Caldesmon PF02029.10 CCD27379.1 - 1.7 6.9 30.3 3.4 5.9 21.0 1.4 1 0 0 1 1 1 0 Caldesmon Ribosomal_L6e PF01159.14 CCD27379.1 - 1.9 8.7 11.5 1.4 9.1 4.5 2.7 2 0 0 2 2 2 0 Ribosomal protein L6e PIN_3 PF13470.1 CCD27379.1 - 5.2 7.7 6.6 10 6.8 4.0 1.9 1 1 0 1 1 1 0 PIN domain ThiF PF00899.16 CCD27380.1 - 3.7e-37 127.1 0.1 6.7e-37 126.3 0.0 1.4 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CCD27380.1 - 0.00011 22.2 0.0 0.00019 21.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 CCD27380.1 - 0.0018 17.2 0.0 0.0043 16.0 0.0 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 CCD27380.1 - 0.008 16.1 0.4 0.016 15.1 0.0 1.7 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.11 CCD27380.1 - 0.0085 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 CCD27380.1 - 0.01 16.1 0.0 0.29 11.4 0.0 2.5 2 1 0 2 2 2 0 XdhC Rossmann domain 3Beta_HSD PF01073.14 CCD27380.1 - 0.033 12.9 0.1 0.05 12.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_17 PF00332.13 CCD27380.1 - 0.038 13.0 0.0 0.063 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 UDPG_MGDP_dh_N PF03721.9 CCD27380.1 - 0.093 12.0 0.1 0.18 11.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Mito_carr PF00153.22 CCD27381.1 - 2.4e-65 216.2 2.0 1.1e-22 79.5 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 CCD27381.1 - 0.024 14.7 0.3 2.9 7.9 0.0 3.0 2 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family YtxH PF12732.2 CCD27381.1 - 4.9 7.5 5.8 6.4 7.2 0.0 3.1 3 1 0 3 3 3 0 YtxH-like protein DUF2370 PF10176.4 CCD27382.1 - 3.2e-77 259.0 0.0 3.2e-77 259.0 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) SNF5 PF04855.7 CCD27383.1 - 1.6e-65 221.0 2.7 1.6e-65 221.0 1.9 3.5 3 1 0 3 3 3 1 SNF5 / SMARCB1 / INI1 Adap_comp_sub PF00928.16 CCD27384.1 - 2.3e-27 95.7 0.0 7.4e-24 84.2 0.0 2.7 3 0 0 3 3 3 2 Adaptor complexes medium subunit family Phycoerythr_ab PF02972.9 CCD27384.1 - 0.15 11.7 1.5 0.41 10.2 0.1 2.4 3 0 0 3 3 3 0 Phycoerythrin, alpha/beta chain adh_short PF00106.20 CCD27385.1 - 5.1e-63 211.9 0.1 2.3e-31 108.9 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCD27385.1 - 5.4e-30 104.4 0.0 7.3e-14 51.8 0.0 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 CCD27385.1 - 1.7e-29 101.6 0.0 3.3e-29 100.7 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain adh_short_C2 PF13561.1 CCD27385.1 - 3e-18 66.4 0.2 5.4e-11 42.7 0.0 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydrat_N PF13452.1 CCD27385.1 - 1.5e-07 31.2 0.0 3.9e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase QCR10 PF09796.4 CCD27386.1 - 1.5e-21 75.7 0.5 2e-21 75.4 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 CCD27386.1 - 0.18 11.5 1.4 0.25 11.0 1.0 1.4 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Bromodomain PF00439.20 CCD27387.1 - 1.6e-28 98.4 7.4 2.5e-17 62.5 0.5 2.7 2 0 0 2 2 2 2 Bromodomain LAMTOR PF15454.1 CCD27388.1 - 1.4e-14 54.1 7.2 1.4e-14 54.1 5.0 2.0 2 1 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DDE_Tnp_ISL3 PF01610.12 CCD27388.1 - 0.037 13.6 0.4 0.037 13.6 0.3 1.9 2 0 0 2 2 2 0 Transposase Pilus_CpaD PF09476.5 CCD27388.1 - 0.047 13.1 1.5 0.058 12.8 0.2 1.7 2 0 0 2 2 2 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF2762 PF10960.3 CCD27388.1 - 0.22 11.2 4.1 0.24 11.1 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) DUF2972 PF11186.3 CCD27388.1 - 0.81 9.5 8.4 1.3 8.8 5.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2972) DUF572 PF04502.8 CCD27388.1 - 1.4 8.0 9.3 1.8 7.7 6.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_L50 PF10501.4 CCD27389.1 - 5.4e-24 84.3 1.8 5.4e-24 84.3 1.3 2.3 2 0 0 2 2 2 1 Ribosomal subunit 39S ABC2_membrane_3 PF12698.2 CCD27389.1 - 0.35 9.8 2.9 0.36 9.8 1.4 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3134 PF11332.3 CCD27389.1 - 4.6 7.4 7.0 0.57 10.3 0.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3134) Oxysterol_BP PF01237.13 CCD27392.1 - 6.6e-89 297.8 0.0 8.7e-89 297.4 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein PAP_central PF04928.12 CCD27393.1 - 1.4e-106 355.0 0.0 1.9e-106 354.5 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CCD27393.1 - 3.8e-48 162.9 0.4 6.9e-48 162.1 0.2 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CCD27393.1 - 5.5e-11 42.6 0.1 1.7e-10 41.1 0.1 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain Dynamin_M PF01031.15 CCD27394.1 - 8.4e-106 353.0 0.1 2.1e-105 351.7 0.0 1.7 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CCD27394.1 - 1.2e-55 187.8 0.1 8.2e-55 185.1 0.0 2.3 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 CCD27394.1 - 1.2e-26 92.4 5.2 3.3e-26 90.9 3.6 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCD27394.1 - 0.0018 18.1 0.7 0.042 13.8 0.5 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCD27394.1 - 0.006 17.0 0.0 0.016 15.6 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 CCD27394.1 - 0.088 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.15 CCD27395.1 - 5.4e-75 250.3 0.0 6.5e-75 250.0 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CCD27395.1 - 1.9e-08 34.2 0.0 3.6e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCD27395.1 - 3e-05 24.8 0.1 4.9e-05 24.1 0.1 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCD27395.1 - 0.00011 21.5 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 CCD27395.1 - 0.00034 20.0 0.0 0.00054 19.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CCD27395.1 - 0.00059 20.1 0.1 0.0014 18.8 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CCD27395.1 - 0.021 15.1 0.2 0.025 14.9 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 CCD27395.1 - 0.028 14.3 0.1 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCD27395.1 - 0.039 13.9 0.1 0.074 13.0 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.13 CCD27395.1 - 0.079 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CPT PF07931.7 CCD27395.1 - 0.082 12.5 0.3 3.1 7.3 0.0 2.4 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 CCD27395.1 - 0.095 13.0 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA_26 PF13500.1 CCD27395.1 - 0.12 11.9 0.0 0.29 10.7 0.0 1.6 1 1 0 1 1 1 0 AAA domain Snf7 PF03357.16 CCD27396.1 - 7.6e-32 110.0 22.9 7.6e-32 110.0 15.9 1.9 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.9 CCD27396.1 - 6.8e-07 28.8 7.6 9e-07 28.4 5.3 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Hpt PF01627.18 CCD27396.1 - 0.061 13.3 0.3 0.061 13.3 0.2 2.0 2 0 0 2 2 2 0 Hpt domain DUF1703 PF08011.6 CCD27396.1 - 0.15 11.7 2.9 0.3 10.8 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1703) Uds1 PF15456.1 CCD27396.1 - 0.16 11.9 9.6 0.059 13.3 0.7 2.4 2 1 0 2 2 2 0 Up-regulated During Septation DUF87 PF01935.12 CCD27396.1 - 1.6 8.4 11.4 0.13 12.0 0.4 2.1 1 1 0 2 2 2 0 Domain of unknown function DUF87 Pox_A_type_inc PF04508.7 CCD27396.1 - 8.3 6.4 8.3 4.9 7.1 2.4 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat PITH PF06201.8 CCD27397.1 - 4.7e-30 104.3 7.2 7.7e-30 103.6 5.0 1.3 1 0 0 1 1 1 1 PITH domain EF-hand_like PF09279.6 CCD27397.1 - 0.029 14.3 1.1 0.18 11.8 0.1 2.3 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like bZIP_1 PF00170.16 CCD27398.1 - 9.8e-06 25.4 11.3 3.3e-05 23.7 7.8 1.9 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 CCD27398.1 - 0.00037 20.0 1.2 0.00087 18.8 0.9 1.6 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain Toprim_3 PF13362.1 CCD27398.1 - 0.23 11.7 1.8 0.25 11.6 0.1 1.9 2 0 0 2 2 2 0 Toprim domain Macoilin PF09726.4 CCD27398.1 - 1.3 7.1 25.1 2.3 6.3 17.4 1.3 1 1 0 1 1 1 0 Transmembrane protein Vps39_2 PF10367.4 CCD27398.1 - 4.2 7.5 8.2 0.64 10.2 0.7 2.7 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 Smr PF01713.16 CCD27399.1 - 1.1e-12 47.9 0.0 2.1e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 CCD27399.1 - 3.9e-12 45.3 0.1 1.6e-07 30.6 0.1 2.6 2 0 0 2 2 2 2 CUE domain CENP-C_C PF11699.3 CCD27400.1 - 2.6e-27 94.6 2.5 6.8e-27 93.2 1.7 1.8 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 CCD27400.1 - 3.5e-24 85.9 8.6 3.5e-24 85.9 6.0 4.3 3 1 1 5 5 5 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 CCD27400.1 - 1.7e-05 24.1 0.0 3.5e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CCD27400.1 - 0.2 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 AraC-like ligand binding domain Pkinase PF00069.20 CCD27401.1 - 4.3e-72 242.3 0.0 7.4e-72 241.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD27401.1 - 8.2e-46 156.1 0.0 1.5e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CCD27401.1 - 2.3e-21 75.9 0.1 1.7e-20 73.1 0.0 2.7 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 CCD27401.1 - 5.2e-06 25.6 0.0 9.9e-05 21.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCD27401.1 - 0.35 10.5 0.0 1.9 8.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family HECT PF00632.20 CCD27402.1 - 1.4e-73 247.8 0.7 2.6e-73 246.9 0.1 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) TRAM_LAG1_CLN8 PF03798.11 CCD27403.1 - 3.6e-35 121.3 25.2 3.6e-35 121.3 17.4 1.8 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CCD27403.1 - 4.5e-20 70.9 0.2 4.5e-20 70.9 0.1 2.1 2 0 0 2 2 2 1 TRAM1-like protein Herpes_LMP1 PF05297.6 CCD27403.1 - 7.2 5.4 6.8 12 4.6 4.7 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) VHS PF00790.14 CCD27404.1 - 1e-33 115.9 3.9 1e-33 115.9 2.7 1.6 2 0 0 2 2 2 1 VHS domain SH3_1 PF00018.23 CCD27404.1 - 4.7e-17 61.0 0.1 8.9e-17 60.2 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCD27404.1 - 9.3e-14 50.7 0.1 1.6e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCD27404.1 - 1.6e-09 37.1 0.0 3.3e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain HsbA PF12296.3 CCD27404.1 - 0.0035 17.1 0.3 0.0035 17.1 0.2 2.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Pex14_N PF04695.8 CCD27404.1 - 0.013 15.5 8.2 0.013 15.5 5.7 3.1 2 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ACP_syn_III PF08545.5 CCD27405.1 - 0.12 12.0 0.3 0.19 11.4 0.2 1.3 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III DUF3529 PF12046.3 CCD27405.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) PNRC PF15365.1 CCD27406.1 - 4.9 7.2 6.3 6.5 6.8 1.0 3.2 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator DUF572 PF04502.8 CCD27407.1 - 1.1e-46 159.5 10.8 1.3e-46 159.3 7.5 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) E6 PF00518.12 CCD27407.1 - 0.076 13.3 0.4 0.27 11.5 0.2 1.9 1 1 0 1 1 1 0 Early Protein (E6) Benyvirus_14KDa PF07255.6 CCD27407.1 - 0.1 12.4 2.3 0.52 10.1 0.0 2.7 2 1 1 3 3 3 0 Benyvirus 14KDa protein Mu-like_Com PF10122.4 CCD27407.1 - 0.21 10.6 3.2 0.22 10.6 0.1 2.5 3 0 0 3 3 3 0 Mu-like prophage protein Com PRP1_N PF06424.7 CCD27407.1 - 0.54 10.5 7.1 0.9 9.8 4.9 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Abhydrolase_1 PF00561.15 CCD27408.1 - 7.7e-22 77.9 0.0 9.9e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCD27408.1 - 1.2e-17 64.0 0.0 2e-17 63.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCD27408.1 - 2.1e-17 63.7 0.0 2.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCD27408.1 - 3.5e-09 36.3 0.0 8.1e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 CCD27408.1 - 7.3e-05 22.3 0.0 0.18 11.2 0.0 3.1 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CCD27408.1 - 0.0013 18.0 0.1 0.012 14.8 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family FSH1 PF03959.8 CCD27408.1 - 0.0093 15.4 0.1 0.03 13.7 0.0 1.8 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.13 CCD27408.1 - 0.025 13.8 0.0 0.11 11.7 0.0 1.9 2 1 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S10 PF00450.17 CCD27408.1 - 0.073 12.2 0.0 0.73 8.9 0.0 2.0 2 0 0 2 2 2 0 Serine carboxypeptidase Pantoate_ligase PF02569.10 CCD27409.1 - 0.17 10.6 0.0 0.33 9.6 0.0 1.4 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase RasGAP PF00616.14 CCD27410.1 - 5.1e-46 156.8 8.8 2.6e-45 154.5 6.1 2.4 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 CCD27410.1 - 7.1e-05 22.5 0.3 0.00019 21.2 0.2 1.6 1 0 0 1 1 1 1 C2 domain Snf7 PF03357.16 CCD27411.1 - 3.1e-18 65.7 8.9 3.1e-18 65.7 6.2 1.9 2 0 0 2 2 2 1 Snf7 DUF4302 PF14135.1 CCD27411.1 - 0.014 14.7 1.8 0.021 14.1 0.5 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4302) Apolipo_F PF15148.1 CCD27411.1 - 0.02 14.2 0.4 0.028 13.7 0.1 1.4 1 1 0 1 1 1 0 Apolipoprotein F MCPVI PF02993.9 CCD27411.1 - 0.045 13.8 1.3 0.051 13.7 0.9 1.1 1 0 0 1 1 1 0 Minor capsid protein VI DnaG_DnaB_bind PF08278.6 CCD27411.1 - 0.098 12.8 3.1 0.079 13.1 1.2 1.6 1 1 0 1 1 1 0 DNA primase DnaG DnaB-binding Rep_4 PF05797.6 CCD27411.1 - 0.23 10.0 4.2 0.31 9.6 2.9 1.2 1 0 0 1 1 1 0 Yeast trans-acting factor (REP1/REP2) DUF3591 PF12157.3 CCD27411.1 - 0.36 9.1 4.0 0.41 8.9 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3591) JHBP PF06585.6 CCD27411.1 - 0.37 9.5 4.2 0.63 8.8 2.9 1.5 1 1 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) U1snRNP70_N PF12220.3 CCD27411.1 - 1.3 9.3 5.1 3 8.2 3.5 1.6 1 1 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF1053 PF06327.9 CCD27411.1 - 8.1 6.8 9.9 1.8 8.9 0.8 2.4 1 1 2 3 3 3 0 Domain of Unknown Function (DUF1053) Glyco_transf_22 PF03901.12 CCD27412.1 - 5.2e-33 114.6 27.5 6.6e-33 114.3 19.1 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Metallophos PF00149.23 CCD27413.1 - 3.6e-40 137.5 1.0 4.7e-40 137.1 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ubiquitin PF00240.18 CCD27414.1 - 7.2e-07 28.5 0.3 8.8e-07 28.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCD27414.1 - 0.00022 20.8 0.3 0.00024 20.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCD27414.1 - 0.05 13.8 0.3 0.18 12.0 0.2 1.8 1 1 0 1 1 1 0 Ubiquitin-like domain Chorismate_bind PF00425.13 CCD27415.1 - 4.2e-66 222.8 0.0 6e-66 222.3 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 CCD27415.1 - 1.3e-34 119.3 0.0 2.1e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 CCD27415.1 - 3.8e-15 56.1 0.0 1.5e-14 54.1 0.0 2.0 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 CCD27415.1 - 3.3e-09 36.4 0.0 6.2e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 NAD_binding_4 PF07993.7 CCD27415.1 - 0.0068 15.3 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein BNR PF02012.15 CCD27415.1 - 0.047 13.5 0.5 0.17 11.8 0.1 2.3 2 0 0 2 2 2 0 BNR/Asp-box repeat Glucosamine_iso PF01182.15 CCD27416.1 - 1.5e-48 165.1 0.0 2.6e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase LMBR1 PF04791.11 CCD27417.1 - 1.2e-15 57.0 28.5 2.9e-15 55.8 19.8 1.6 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF3215 PF11503.3 CCD27418.1 - 1.1e-19 69.8 0.0 1.4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) Ribosom_S12_S23 PF00164.20 CCD27419.1 - 2.5e-44 149.5 0.9 3.5e-44 149.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S19 PF00203.16 CCD27420.1 - 5.2e-22 77.2 0.0 7e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 DEAD PF00270.24 CCD27421.1 - 9.3e-40 135.8 0.9 2.2e-39 134.6 0.7 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCD27421.1 - 1.1e-17 63.6 0.1 2.6e-17 62.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Flavi_DEAD PF07652.9 CCD27421.1 - 0.00074 19.2 0.3 0.07 12.8 0.1 2.8 2 1 0 2 2 2 1 Flavivirus DEAD domain Daxx PF03344.10 CCD27421.1 - 0.55 8.6 41.4 0.12 10.8 26.3 1.6 2 0 0 2 2 2 0 Daxx Family Cation_efflux PF01545.16 CCD27422.1 - 8e-06 25.1 17.2 8e-06 25.1 11.9 1.7 2 0 0 2 2 2 1 Cation efflux family CsgG PF03783.9 CCD27423.1 - 0.097 11.7 0.3 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG UbiA PF01040.13 CCD27424.1 - 2.3e-31 108.9 19.2 3e-31 108.5 13.3 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family EpuA PF11772.3 CCD27424.1 - 1.2 8.6 4.4 6.9 6.1 0.9 2.7 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta GHMP_kinases_N PF00288.21 CCD27425.1 - 4.2e-10 39.5 0.8 9.6e-10 38.3 0.5 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF1819 PF08849.6 CCD27425.1 - 0.085 12.2 0.1 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) DUF3354 PF11834.3 CCD27425.1 - 0.094 12.3 0.0 0.34 10.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3354) WD40 PF00400.27 CCD27426.1 - 1e-63 209.0 11.0 1.5e-11 43.7 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CCD27426.1 - 2.3e-25 88.5 12.3 2.3e-25 88.5 8.5 2.6 2 0 0 2 2 2 1 Tup N-terminal ADIP PF11559.3 CCD27426.1 - 0.061 13.2 35.7 0.14 12.0 24.8 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding LMBR1 PF04791.11 CCD27426.1 - 1.4 7.4 4.7 2.3 6.6 3.2 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein APG6 PF04111.7 CCD27426.1 - 3.8 6.4 31.3 6.4 5.7 21.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 CCD27426.1 - 4 6.3 29.1 6.5 5.6 20.2 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med15 PF09606.5 CCD27426.1 - 7.1 4.6 77.6 12 3.9 53.8 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PfUIS3 PF11567.3 CCD27427.1 - 0.0057 16.7 1.4 0.01 15.9 0.3 1.9 2 0 0 2 2 2 1 Plasmodium falciparum UIS3 membrane protein VMA21 PF09446.5 CCD27427.1 - 2 8.4 5.7 1 9.3 0.3 2.5 2 0 0 2 2 2 0 VMA21-like domain DUF2296 PF10058.4 CCD27428.1 - 0.09 12.5 2.9 0.43 10.3 0.3 2.5 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-P11 PF03854.9 CCD27428.1 - 6.8 6.2 6.9 9.4 5.8 0.0 3.4 2 1 1 3 3 3 0 P-11 zinc finger Pkinase PF00069.20 CCD27430.1 - 3.4e-74 249.2 0.1 6e-74 248.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCD27430.1 - 6.7e-32 110.5 0.1 4.6e-31 107.8 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCD27430.1 - 5.9e-09 35.3 0.0 5.3e-06 25.6 0.0 2.6 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.9 CCD27430.1 - 0.074 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MCR_beta PF02241.13 CCD27430.1 - 0.2 10.8 0.0 0.35 10.0 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain CDC50 PF03381.10 CCD27431.1 - 1.2e-97 326.4 4.0 1.6e-97 326.0 2.8 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Mso1_Sec1_bdg PF14475.1 CCD27432.1 - 4.2e-19 67.6 0.3 1.8e-18 65.6 0.0 2.1 2 0 0 2 2 2 1 Sec1-binding region of Mso1 DUF605 PF04652.11 CCD27432.1 - 0.74 9.1 21.4 0.93 8.8 14.8 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 CCD27432.1 - 8.8 6.1 17.6 11 5.8 12.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KAT11 PF08214.6 CCD27433.1 - 1.3e-85 287.5 7.4 1.5e-85 287.3 5.1 1.0 1 0 0 1 1 1 1 Histone acetylation protein Ribosomal_S6 PF01250.12 CCD27434.1 - 1.2e-05 25.0 0.0 2.4e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S6 RTP801_C PF07809.6 CCD27434.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.7 1 1 1 2 2 2 0 RTP801 C-terminal region PAP2 PF01569.16 CCD27435.1 - 1.3e-13 50.7 5.9 1.3e-13 50.7 4.1 2.3 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CCD27435.1 - 2.7e-07 30.3 4.1 2.7e-07 30.3 2.8 2.2 2 0 0 2 2 2 1 PAP2 superfamily COX7C PF02935.11 CCD27435.1 - 0.39 10.5 4.2 3.9 7.3 0.9 2.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc TFIIS_M PF07500.9 CCD27436.1 - 6.6e-18 64.8 2.0 6.6e-18 64.8 1.4 2.5 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 CCD27436.1 - 5.2e-11 42.0 5.4 1e-10 41.1 3.7 1.5 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 CCD27436.1 - 7.7e-05 23.1 0.2 0.00021 21.7 0.0 1.9 2 0 0 2 2 2 1 SPOC domain zf-CW PF07496.10 CCD27436.1 - 0.024 14.3 0.4 0.065 12.9 0.2 1.8 1 0 0 1 1 1 0 CW-type Zinc Finger Protamine_P2 PF00841.14 CCD27436.1 - 9.6 6.8 11.2 69 4.0 0.9 4.1 4 0 0 4 4 4 0 Sperm histone P2 Ribosomal_L14e PF01929.12 CCD27437.1 - 5.8e-30 103.4 0.2 8e-30 103.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CCD27437.1 - 9e-05 22.0 1.5 0.00021 20.8 1.1 1.7 1 0 0 1 1 1 1 KOW motif Corona_S2 PF01601.11 CCD27438.1 - 0.0085 14.2 2.0 0.0092 14.1 1.4 1.1 1 0 0 1 1 1 1 Coronavirus S2 glycoprotein DUF4492 PF14899.1 CCD27438.1 - 0.032 13.7 0.8 0.062 12.8 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) SF-assemblin PF06705.6 CCD27438.1 - 0.038 13.1 0.1 0.042 12.9 0.1 1.1 1 0 0 1 1 1 0 SF-assemblin/beta giardin Synaptobrevin PF00957.16 CCD27438.1 - 0.043 13.4 3.3 0.098 12.2 2.2 1.7 1 1 0 1 1 1 0 Synaptobrevin SNARE PF05739.14 CCD27438.1 - 0.14 11.8 1.7 0.19 11.4 1.2 1.2 1 0 0 1 1 1 0 SNARE domain HsdM_N PF12161.3 CCD27438.1 - 0.17 12.2 1.5 0.23 11.9 1.0 1.1 1 0 0 1 1 1 0 HsdM N-terminal domain MitMem_reg PF13012.1 CCD27438.1 - 0.2 11.7 2.2 0.23 11.5 1.5 1.1 1 0 0 1 1 1 0 Maintenance of mitochondrial structure and function F-actin_cap_A PF01267.12 CCD27439.1 - 1e-71 241.1 5.7 1.2e-71 240.9 4.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Hyphal_reg_CWP PF11765.3 CCD27441.1 - 4.2e-43 147.3 17.6 4.2e-43 147.3 12.2 1.5 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal PapC_C PF13953.1 CCD27441.1 - 1.6 8.4 5.3 6.9 6.4 0.3 3.3 4 1 0 4 4 4 0 PapC C-terminal domain SNF2_N PF00176.18 CCD27442.1 - 7.9e-71 238.2 0.0 1.2e-70 237.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 CCD27442.1 - 4.2e-53 180.0 5.1 2e-52 177.8 2.9 2.1 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 CCD27442.1 - 1.1e-12 47.5 0.0 2.9e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCD27442.1 - 8.7e-09 34.6 5.6 1.1e-08 34.2 0.2 3.4 3 1 0 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CCD27442.1 - 8.4e-05 22.1 0.0 0.0002 20.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CCD27442.1 - 0.0039 17.0 0.0 0.024 14.4 0.0 2.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DUF1170 PF06663.8 CCD27442.1 - 0.031 14.1 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1170) Ran-binding PF05508.6 CCD27443.1 - 1.1e-114 382.4 4.8 1.8e-114 381.7 3.3 1.3 1 0 0 1 1 1 1 RanGTP-binding protein DUF1664 PF07889.7 CCD27443.1 - 2.8 7.7 6.7 6.3 6.6 0.8 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) Copper-fist PF00649.13 CCD27444.1 - 6.2e-21 73.3 0.3 6.2e-21 73.3 0.2 2.6 1 1 1 2 2 2 1 Copper fist DNA binding domain Cullin PF00888.17 CCD27445.1 - 4.7e-95 319.3 35.7 6.4e-95 318.8 24.7 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CCD27445.1 - 8.5e-17 60.7 2.1 3.6e-16 58.7 1.5 2.2 1 0 0 1 1 1 1 Cullin protein neddylation domain PMC2NT PF08066.7 CCD27445.1 - 0.0092 16.2 1.2 15 5.9 0.1 3.9 3 0 0 3 3 3 2 PMC2NT (NUC016) domain Pex24p PF06398.6 CCD27446.1 - 1.2e-83 280.8 13.8 1.5e-83 280.6 9.6 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF2556 PF10831.3 CCD27447.1 - 0.0014 18.1 0.1 0.22 11.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2556) 7TMR-DISM_7TM PF07695.6 CCD27447.1 - 0.0027 17.4 6.3 0.0037 16.9 4.4 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling DUF3397 PF11877.3 CCD27447.1 - 0.62 10.0 12.6 0.11 12.5 2.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3397) SdpI PF13630.1 CCD27447.1 - 2.9 7.6 8.7 16 5.3 2.5 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family TcpE PF12648.2 CCD27447.1 - 4.7 7.4 7.9 1.7 8.8 0.4 2.1 1 1 1 2 2 2 0 TcpE family Abhydrolase_6 PF12697.2 CCD27448.1 - 5.8e-16 59.0 0.0 9.6e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCD27448.1 - 1.9e-11 43.9 0.0 3.9e-11 42.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCD27448.1 - 1.2e-05 25.0 0.0 1.7e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CCD27448.1 - 2.1e-05 24.2 0.0 2.9e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein BAAT_C PF08840.6 CCD27448.1 - 0.00034 20.4 0.0 0.00054 19.7 0.0 1.2 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 CCD27448.1 - 0.00046 19.6 0.0 0.0014 18.1 0.0 1.8 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 CCD27448.1 - 0.026 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.9 CCD27448.1 - 0.044 13.0 0.0 0.1 11.8 0.0 1.6 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Lipase_2 PF01674.13 CCD27448.1 - 0.06 12.6 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) DUF3974 PF13120.1 CCD27449.1 - 0.056 13.2 0.0 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3974) PALP PF00291.20 CCD27450.1 - 1.3e-58 198.6 0.0 1.5e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme 3Beta_HSD PF01073.14 CCD27451.1 - 2.4e-82 275.8 0.0 3.4e-82 275.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCD27451.1 - 3.7e-26 92.0 0.0 4.6e-26 91.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCD27451.1 - 1.2e-13 50.6 0.0 6.3e-13 48.2 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 CCD27451.1 - 8.8e-09 34.6 0.0 1.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CCD27451.1 - 9.9e-07 28.9 0.0 1.6e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CCD27451.1 - 0.0001 21.3 0.0 0.00035 19.5 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CCD27451.1 - 0.052 13.4 0.0 0.15 11.9 0.0 1.7 1 1 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 CCD27451.1 - 0.14 11.8 0.0 0.45 10.1 0.0 1.7 1 1 0 1 1 1 0 KR domain N6-adenineMlase PF10237.4 CCD27452.1 - 9.7e-63 210.6 0.0 1.6e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase DUF4456 PF14644.1 CCD27452.1 - 0.0053 15.9 0.7 0.0073 15.5 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4456) DUF4078 PF13300.1 CCD27452.1 - 0.23 11.6 4.6 0.38 10.9 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4078) CTP_transf_2 PF01467.21 CCD27453.1 - 7e-20 71.6 0.0 8.5e-11 42.1 0.1 2.6 2 1 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 CCD27453.1 - 1.4e-05 24.7 0.4 0.14 11.7 0.0 3.2 3 0 0 3 3 3 3 FAD synthetase Prp18 PF02840.10 CCD27454.1 - 2.4e-42 144.2 0.5 2.4e-42 144.2 0.4 1.7 2 0 0 2 2 2 1 Prp18 domain Mt_ATP-synt_B PF05405.9 CCD27454.1 - 0.13 11.7 1.4 0.28 10.6 0.7 1.7 1 1 0 1 1 1 0 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) TFIIF_beta PF02270.10 CCD27455.1 - 1.1e-94 317.3 14.8 2.1e-94 316.3 10.3 1.5 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit Ribosomal_L38e PF01781.13 CCD27456.1 - 1.9e-27 94.8 4.6 2.2e-27 94.6 3.2 1.1 1 0 0 1 1 1 1 Ribosomal L38e protein family MinC_N PF05209.8 CCD27456.1 - 0.075 12.8 0.1 0.13 12.0 0.1 1.5 1 1 0 1 1 1 0 Septum formation inhibitor MinC, N-terminal domain Ferrochelatase PF00762.14 CCD27458.1 - 2.2e-87 292.9 0.0 2.5e-87 292.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase MBOAT PF03062.14 CCD27459.1 - 1.2e-60 205.3 17.6 1.2e-60 205.3 12.2 1.8 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family AAA_23 PF13476.1 CCD27459.1 - 1.4 9.2 8.4 2.6 8.3 5.8 1.4 1 0 0 1 1 1 0 AAA domain Saccharop_dh PF03435.13 CCD27460.1 - 1.7e-126 422.3 0.0 2e-126 422.0 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 CCD27460.1 - 2.5e-08 34.1 0.2 4e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 CCD27460.1 - 4.5e-05 23.7 0.1 9.3e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 CCD27460.1 - 5.4e-05 23.2 0.2 9.5e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCD27460.1 - 0.00044 19.5 0.2 0.0051 16.0 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 CCD27460.1 - 0.0048 15.6 0.1 0.0074 15.0 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_3 PF03447.11 CCD27460.1 - 0.0081 16.5 0.2 0.015 15.7 0.1 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain IlvN PF07991.7 CCD27460.1 - 0.012 15.0 0.4 0.07 12.5 0.1 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain DapB_N PF01113.15 CCD27460.1 - 0.017 15.0 0.1 0.029 14.2 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF2325 PF10087.4 CCD27460.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) GFO_IDH_MocA PF01408.17 CCD27460.1 - 0.076 13.5 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Epimerase PF01370.16 CCD27460.1 - 0.082 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family SIS PF01380.17 CCD27461.1 - 6.1e-65 216.7 0.0 5.4e-33 113.3 0.1 2.2 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CCD27461.1 - 1e-28 100.0 0.0 3.2e-21 75.4 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCD27461.1 - 7.5e-18 64.7 0.0 1.6e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CCD27461.1 - 8.4e-11 41.6 0.0 1.7e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CCD27461.1 - 6e-09 34.9 0.1 1e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II COMPASS-Shg1 PF05205.7 CCD27461.1 - 0.067 13.4 0.2 0.26 11.5 0.0 2.1 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 SIS_2 PF13580.1 CCD27461.1 - 0.1 12.3 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 SIS domain Peptidase_M18 PF02127.10 CCD27462.1 - 3.3e-140 467.4 0.0 4.7e-140 466.9 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Aminotran_1_2 PF00155.16 CCD27463.1 - 5.9e-65 219.5 0.0 7.3e-65 219.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NUMOD1 PF07453.8 CCD27463.1 - 0.0043 16.8 0.2 0.016 15.0 0.0 2.1 2 0 0 2 2 2 1 NUMOD1 domain MFS_1 PF07690.11 CCD27464.1 - 1.1e-29 103.3 45.4 1.4e-17 63.4 17.8 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily Nnf1 PF03980.9 CCD27465.1 - 2.4e-26 91.8 12.4 5.9e-26 90.6 8.6 1.8 1 0 0 1 1 1 1 Nnf1 PilJ PF13675.1 CCD27465.1 - 0.026 14.8 2.0 0.56 10.5 0.1 2.8 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF1103 PF06513.6 CCD27465.1 - 0.091 12.1 6.3 0.13 11.6 4.4 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) DUF3422 PF11902.3 CCD27465.1 - 0.11 11.3 1.9 0.18 10.6 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) TnpV PF14198.1 CCD27465.1 - 0.13 12.2 3.0 4.4 7.2 0.1 2.4 2 0 0 2 2 2 0 Transposon-encoded protein TnpV Apolipoprotein PF01442.13 CCD27465.1 - 0.14 11.6 7.5 0.029 13.9 1.4 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain YjcZ PF13990.1 CCD27465.1 - 0.19 10.8 6.7 5.1 6.1 0.1 3.0 1 1 2 3 3 3 0 YjcZ-like protein SPX PF03105.14 CCD27465.1 - 0.47 10.2 14.7 4 7.1 10.2 2.1 1 1 0 1 1 1 0 SPX domain DUF4407 PF14362.1 CCD27465.1 - 1 8.2 4.0 1.6 7.6 2.7 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.10 CCD27465.1 - 1.8 8.0 10.6 0.14 11.6 3.3 2.3 2 1 0 2 2 2 0 Septum formation initiator DUF1664 PF07889.7 CCD27465.1 - 3.7 7.3 6.7 1.4 8.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 CCD27465.1 - 4.9 7.6 6.3 1.5 9.3 0.5 2.5 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) Med4 PF10018.4 CCD27465.1 - 5.6 6.3 13.7 0.3 10.4 4.0 2.5 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 V_ATPase_I PF01496.14 CCD27465.1 - 7.5 4.2 7.8 12 3.5 5.4 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family RRM_1 PF00076.17 CCD27466.1 - 0.00015 21.2 0.0 0.029 14.0 0.0 2.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCD27466.1 - 0.003 17.3 0.1 0.047 13.5 0.1 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCD27466.1 - 0.0045 16.9 0.0 0.028 14.4 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GAGA_bind PF06217.7 CCD27466.1 - 4.7 7.0 14.1 1.1 9.1 1.4 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family Spore_coat_CotO PF14153.1 CCD27466.1 - 8 5.8 24.6 0.023 14.1 7.0 2.3 2 0 0 2 2 2 0 Spore coat protein CotO NGP1NT PF08153.7 CCD27467.1 - 6.7e-49 165.1 0.4 1.3e-48 164.1 0.3 1.5 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CCD27467.1 - 9.3e-20 70.7 0.0 5.1e-15 55.4 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCD27467.1 - 2.5e-05 23.6 0.0 0.00016 20.9 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 CCD27467.1 - 9.8e-05 21.6 0.1 0.097 11.9 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 CCD27467.1 - 0.0013 17.9 0.0 0.0029 16.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 CCD27467.1 - 0.0015 18.3 9.3 0.5 10.1 4.5 4.1 2 1 0 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 CCD27467.1 - 0.0029 17.0 0.0 0.62 9.4 0.0 3.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain CAF1 PF04857.15 CCD27468.1 - 3.7e-57 193.6 0.2 3.7e-57 193.6 0.1 1.9 2 0 0 2 2 2 1 CAF1 family ribonuclease DUF2732 PF10809.3 CCD27468.1 - 0.062 12.8 0.0 0.2 11.2 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) NTF2 PF02136.15 CCD27469.1 - 1.6e-13 51.0 0.8 4.9e-13 49.4 0.5 1.9 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Ribosomal_S28e PF01200.13 CCD27470.1 - 1e-33 114.8 3.3 1.1e-33 114.7 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e PIN_4 PF13638.1 CCD27471.1 - 2.2e-33 115.2 0.4 2.2e-33 115.2 0.3 2.5 2 1 0 2 2 2 1 PIN domain Phage_int_SAM_4 PF13495.1 CCD27471.1 - 0.076 13.3 2.2 1.5 9.1 0.5 2.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain RHD3 PF05879.7 CCD27472.1 - 1.3e-242 806.9 24.3 1.6e-242 806.7 16.8 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Dynamin_N PF00350.18 CCD27472.1 - 6.6e-05 22.8 0.4 0.00047 20.0 0.0 2.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CCD27472.1 - 0.0018 18.2 0.1 0.009 15.9 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCD27472.1 - 0.0038 17.7 0.1 0.014 15.8 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein Cas_csx3 PF09620.5 CCD27472.1 - 0.11 12.3 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) DUF410 PF04190.8 CCD27473.1 - 6.3e-73 245.5 5.4 7.9e-73 245.1 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF2802 PF10975.3 CCD27473.1 - 0.041 13.6 0.1 0.1 12.3 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2802) NUDIX PF00293.23 CCD27474.1 - 6.7e-17 61.3 0.0 7.8e-17 61.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Zn_clus PF00172.13 CCD27475.1 - 1.8e-09 37.3 9.0 4.2e-09 36.1 6.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DcpS PF05652.7 CCD27476.1 - 1e-36 125.6 0.2 1.8e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 CCD27476.1 - 3.9e-28 98.0 0.1 8.4e-28 96.9 0.1 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding tRNA-synt_1c PF00749.16 CCD27477.1 - 8.1e-113 376.2 0.0 1.5e-112 375.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 CCD27477.1 - 7.8e-57 191.3 2.6 1.3e-56 190.6 1.8 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 CCD27477.1 - 6.7e-30 104.0 0.8 5.7e-28 97.7 0.3 2.8 2 1 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 CCD27477.1 - 2.9e-24 85.5 6.9 6.3e-24 84.4 4.8 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 DAGK_cat PF00781.19 CCD27478.1 - 9.3e-25 86.5 0.0 1.6e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Tim54 PF11711.3 CCD27478.1 - 0.022 13.3 0.0 0.098 11.2 0.0 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Peptidase_S8 PF00082.17 CCD27479.1 - 7.9e-55 185.9 6.4 1.2e-54 185.3 4.5 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CCD27479.1 - 2.6e-13 50.3 0.3 2.6e-13 50.3 0.2 2.1 2 0 0 2 2 2 1 Peptidase inhibitor I9 PGM_PMM_I PF02878.11 CCD27480.1 - 2.3e-16 59.5 0.1 2.1e-09 36.9 0.0 2.4 1 1 1 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CCD27480.1 - 9e-09 35.6 0.0 2.3e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCD27480.1 - 1.1e-08 34.9 0.1 3e-08 33.5 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 CCD27480.1 - 0.0018 18.2 0.6 0.0057 16.6 0.2 2.0 2 1 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III WD40 PF00400.27 CCD27481.1 - 2e-27 94.0 0.3 6.9e-06 25.7 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCD27481.1 - 1.2e-23 82.7 0.3 3.2e-23 81.3 0.2 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Coatomer_WDAD PF04053.9 CCD27481.1 - 0.021 13.6 0.5 0.12 11.0 0.4 2.0 1 1 0 1 1 1 0 Coatomer WD associated region DNA_pol_phi PF04931.8 CCD27482.1 - 8.4e-144 480.2 36.7 1.2e-143 479.7 25.5 1.2 1 0 0 1 1 1 1 DNA polymerase phi UME PF08064.8 CCD27482.1 - 1.4 8.8 9.3 0.39 10.6 1.3 3.8 3 1 0 3 3 3 0 UME (NUC010) domain Atrophin-1 PF03154.10 CCD27482.1 - 4 5.4 8.0 6 4.8 5.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family LMBR1 PF04791.11 CCD27483.1 - 0.11 11.0 3.5 0.12 10.9 2.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Aconitase PF00330.15 CCD27484.1 - 1.1e-174 581.3 0.0 2.1e-174 580.4 0.0 1.5 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCD27484.1 - 2e-42 144.3 0.0 3.5e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain CRAL_TRIO_2 PF13716.1 CCD27485.1 - 1.3e-31 109.4 0.6 4.7e-31 107.7 0.4 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 CCD27485.1 - 3.6e-10 39.6 0.2 3.6e-10 39.6 0.2 1.8 2 0 0 2 2 2 1 RhoGAP domain PALP PF00291.20 CCD27486.1 - 3.8e-62 210.2 0.0 4.3e-62 210.1 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 CCD27486.1 - 0.11 11.9 0.1 0.33 10.3 0.1 1.8 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Sugar_tr PF00083.19 CCD27488.1 - 1.3e-165 551.4 33.1 1.5e-165 551.2 23.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCD27488.1 - 6.1e-29 100.8 46.4 1.8e-23 82.8 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily G6PD_C PF02781.11 CCD27489.1 - 3.4e-103 344.5 0.0 4.4e-103 344.1 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CCD27489.1 - 2.7e-55 187.4 0.0 4.4e-55 186.7 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain FMN_dh PF01070.13 CCD27490.1 - 7.7e-112 373.6 0.0 8.9e-112 373.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 CCD27490.1 - 4.4e-06 25.8 0.0 7.1e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 CCD27490.1 - 0.002 17.3 0.0 0.0038 16.4 0.0 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCD27490.1 - 0.023 13.6 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 CCD27490.1 - 0.03 13.3 0.0 7.4 5.5 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.11 CCD27491.1 - 3.9e-24 85.0 10.7 1.6e-23 83.0 7.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily PhoQ_Sensor PF08918.5 CCD27492.1 - 0.016 14.7 0.0 0.027 13.9 0.0 1.3 1 0 0 1 1 1 0 PhoQ Sensor GalKase_gal_bdg PF10509.4 CCK73391.1 - 6.1e-21 73.4 0.0 1.4e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CCK73391.1 - 1.1e-14 54.2 0.3 1.9e-14 53.4 0.2 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCK73391.1 - 1.5e-13 50.7 0.0 2.7e-12 46.6 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal DUF1748 PF08520.5 CCK73391.1 - 0.066 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) Erf4 PF10256.4 CCK73392.1 - 7.4e-30 103.2 0.0 1.1e-29 102.6 0.0 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Cyclin_N PF00134.18 CCK73393.1 - 1.3e-10 40.9 0.1 1.8e-10 40.4 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCK73393.1 - 0.0007 20.0 0.0 0.001 19.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin RVT_1 PF00078.22 CCK73394.1 - 2.2e-25 89.2 0.1 5.5e-25 87.9 0.1 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCK73394.1 - 6.3e-19 68.2 0.8 2.3e-18 66.4 0.0 2.4 3 0 0 3 3 3 1 Integrase core domain Asp_protease_2 PF13650.1 CCK73394.1 - 5.6e-09 36.3 0.0 1.2e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 CCK73394.1 - 3.7e-05 23.5 0.0 0.00016 21.5 0.0 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CCK73394.1 - 6.7e-05 22.6 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CCK73394.1 - 7.5e-05 22.6 0.1 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Retroviral aspartyl protease zf-CCHC PF00098.18 CCK73394.1 - 0.00012 21.8 1.7 0.00012 21.8 1.2 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_4 PF14392.1 CCK73394.1 - 0.73 9.5 7.7 0.085 12.5 0.3 3.1 3 0 0 3 3 3 0 Zinc knuckle HLH PF00010.21 CCK73395.1 - 0.00057 19.5 1.4 0.00084 18.9 0.1 1.9 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF1751 PF08551.5 CCK73396.1 - 7.5e-26 90.3 3.4 7.5e-26 90.3 2.4 2.3 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 CCK73396.1 - 0.48 10.4 8.6 0.16 11.9 4.1 1.6 2 0 0 2 2 2 0 Rhomboid family Keratin_assoc PF09775.4 CCK73396.1 - 1.5 8.3 5.8 0.76 9.3 0.5 2.6 1 1 2 3 3 3 0 Keratinocyte-associated protein 2 PTS_2-RNA PF01885.11 CCK73397.1 - 1.4e-58 197.2 0.1 2e-58 196.7 0.1 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family La PF05383.12 CCK73397.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 La domain CorA PF01544.13 CCK73398.1 - 7.8e-42 143.2 0.7 7.1e-24 84.3 0.0 2.5 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF2231 PF09990.4 CCK73398.1 - 0.075 13.3 0.4 0.13 12.6 0.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF1469 PF07332.6 CCK73398.1 - 0.28 10.9 0.1 0.48 10.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Fungal_trans PF04082.13 CCK73399.1 - 1.5e-16 60.0 4.9 1.5e-16 60.0 3.4 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCK73399.1 - 1.3e-08 34.5 13.8 2.4e-08 33.7 9.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RFC1 PF08519.7 CCK73399.1 - 0.0084 15.8 3.9 0.061 13.0 0.1 3.3 3 1 1 4 4 4 1 Replication factor RFC1 C terminal domain Vps23_core PF09454.5 CCK73401.1 - 1.1e-21 76.1 0.3 3.1e-21 74.7 0.1 1.9 2 0 0 2 2 2 1 Vps23 core domain UEV PF05743.8 CCK73401.1 - 1.6e-05 24.5 0.1 5.7e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 UEV domain ALS_ss_C PF10369.4 CCK73402.1 - 7.8e-20 70.3 0.2 3.2e-19 68.4 0.0 2.1 3 0 0 3 3 3 1 Small subunit of acetolactate synthase ACT PF01842.20 CCK73402.1 - 1.4e-11 43.6 0.7 2.3e-11 42.9 0.1 1.7 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.1 CCK73402.1 - 6.4e-09 35.4 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain Limkain-b1 PF11608.3 CCK73402.1 - 0.0054 16.4 0.0 0.029 14.1 0.0 2.2 2 0 0 2 2 2 1 Limkain b1 ACT_4 PF13291.1 CCK73402.1 - 0.019 15.2 0.1 0.48 10.8 0.0 2.5 2 0 0 2 2 2 0 ACT domain DUF1325 PF07039.6 CCK73403.1 - 2.2e-36 124.3 0.0 4.3e-36 123.3 0.0 1.5 2 0 0 2 2 2 1 SGF29 tudor-like domain DUF4537 PF15057.1 CCK73403.1 - 0.012 15.4 0.0 0.094 12.4 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4537) Agenet PF05641.7 CCK73403.1 - 0.032 14.3 0.2 0.83 9.8 0.0 2.7 3 0 0 3 3 3 0 Agenet domain PAX PF00292.13 CCK73403.1 - 0.13 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 'Paired box' domain RRM_1 PF00076.17 CCK73404.1 - 1.6e-57 191.0 0.0 6.7e-20 70.5 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCK73404.1 - 2.7e-37 126.5 0.0 2.1e-14 53.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCK73404.1 - 4.3e-19 68.1 0.0 6.9e-07 29.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCK73404.1 - 4.1e-05 23.2 0.0 0.57 9.9 0.0 3.0 3 1 0 3 3 3 2 Limkain b1 DUF3507 PF12015.3 CCK73405.1 - 8.4e-40 136.2 0.5 2e-39 134.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF2036 PF09724.4 CCK73406.1 - 3.4e-79 266.3 1.0 3.9e-79 266.1 0.7 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Aminotran_5 PF00266.14 CCK73407.1 - 7.2e-98 327.7 0.2 1.3e-97 326.9 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCK73407.1 - 7.8e-10 38.3 0.2 1.8e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CCK73407.1 - 2.9e-08 33.0 0.0 4.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CCK73407.1 - 5.6e-07 28.9 0.1 1.3e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 CCK73407.1 - 0.00013 20.5 0.0 0.0002 19.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Iso_dh PF00180.15 CCK73408.1 - 1.4e-130 435.3 0.0 1.6e-130 435.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DNA_ligase_aden PF01653.13 CCK73408.1 - 0.088 11.7 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain RFX_DNA_binding PF02257.10 CCK73409.1 - 2.3e-34 117.3 0.2 5.4e-34 116.1 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain DnaJ PF00226.26 CCK73410.1 - 1.2e-24 85.8 0.9 1.8e-24 85.2 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCK73410.1 - 3.2e-24 84.6 0.7 7.2e-21 73.8 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain Methyltransf_23 PF13489.1 CCK73411.1 - 1.5e-24 86.5 0.0 2.2e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCK73411.1 - 1e-19 70.6 0.0 1.4e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCK73411.1 - 2.5e-14 53.8 0.0 4.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCK73411.1 - 3.7e-14 52.9 0.0 6.5e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCK73411.1 - 1.8e-12 47.5 0.0 6.5e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCK73411.1 - 2.1e-09 37.6 0.0 5.9e-09 36.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 CCK73411.1 - 3.4e-08 32.9 0.0 4.9e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CCK73411.1 - 2.9e-07 30.0 0.0 5.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 CCK73411.1 - 3.6e-07 29.5 0.0 4.9e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 CCK73411.1 - 1.3e-05 24.6 0.0 2.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_26 PF13659.1 CCK73411.1 - 4.2e-05 23.5 0.0 0.00011 22.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 CCK73411.1 - 0.00045 19.1 0.0 0.001 18.0 0.0 1.5 1 1 0 1 1 1 1 DREV methyltransferase MetW PF07021.7 CCK73411.1 - 0.00059 19.2 0.0 0.0011 18.3 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 CCK73411.1 - 0.0035 17.0 0.0 0.006 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCK73411.1 - 0.0084 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 CCK73411.1 - 0.01 15.1 0.1 0.19 11.0 0.0 2.3 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_4 PF02390.12 CCK73411.1 - 0.029 13.3 0.0 0.73 8.8 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase RrnaAD PF00398.15 CCK73411.1 - 0.033 13.2 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase tRNA-synt_1b PF00579.20 CCK73412.1 - 9.1e-21 74.2 0.0 6.5e-15 55.0 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Peptidase_M16_C PF05193.16 CCK73413.1 - 1.1e-16 61.0 0.1 8.9e-14 51.5 0.0 3.1 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCK73413.1 - 6.3e-09 35.7 0.1 3.4e-07 30.1 0.0 3.3 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) THOC7 PF05615.8 CCK73413.1 - 0.027 14.7 0.2 1.3 9.2 0.0 3.0 3 0 0 3 3 3 0 Tho complex subunit 7 Pkinase PF00069.20 CCK73414.1 - 2.1e-63 213.9 0.0 4.1e-63 212.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCK73414.1 - 1.3e-32 112.9 0.0 2.2e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCK73414.1 - 7e-07 28.4 0.0 3.8e-06 26.0 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCK73414.1 - 0.0066 15.5 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCK73414.1 - 0.05 13.3 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HlyIII PF03006.15 CCK73415.1 - 4.5e-16 58.9 24.2 5.4e-16 58.6 16.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related UvrD_C PF13361.1 CCK73416.1 - 1.1e-48 166.5 3.5 1.1e-48 166.5 2.4 2.4 2 2 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CCK73416.1 - 1.2e-35 123.3 8.8 1.9e-17 63.5 0.5 3.4 2 2 1 3 3 3 2 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 CCK73416.1 - 2.1e-11 43.7 0.0 0.00014 21.4 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 CCK73416.1 - 6.4e-09 35.8 0.0 2.3e-08 34.0 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CCK73416.1 - 7.9e-09 35.1 0.0 2.1e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CCK73416.1 - 3e-05 23.7 0.3 0.00032 20.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_12 PF13087.1 CCK73416.1 - 0.00011 21.6 0.5 0.023 14.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CCK73416.1 - 0.0017 18.2 1.2 2.1 8.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 CCK73416.1 - 0.0026 17.3 0.0 0.31 10.5 0.0 2.8 3 0 0 3 3 3 1 AAA domain V-ATPase_H_C PF11698.3 CCK73416.1 - 0.024 14.5 0.2 0.39 10.6 0.0 2.8 2 0 0 2 2 2 0 V-ATPase subunit H DKCLD PF08068.7 CCK73417.1 - 2e-29 101.3 0.2 9.4e-29 99.1 0.1 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 CCK73417.1 - 2.5e-21 76.3 5.9 6.8e-20 71.7 0.0 3.8 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CCK73417.1 - 1.7e-19 69.3 1.1 3.2e-19 68.4 0.7 1.5 1 0 0 1 1 1 1 PUA domain GAGA_bind PF06217.7 CCK73417.1 - 0.28 11.0 20.2 0.4 10.5 14.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DDHD PF02862.12 CCK73417.1 - 2.3 7.9 15.8 3.7 7.2 10.9 1.4 1 0 0 1 1 1 0 DDHD domain FLO_LFY PF01698.11 CCK73417.1 - 5.5 5.7 21.7 7.1 5.3 15.1 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein AAA_17 PF13207.1 CCK73418.1 - 7.7e-09 36.4 0.1 8.5e-08 33.0 0.0 2.6 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCK73418.1 - 4.9e-08 33.3 0.0 7.8e-07 29.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCK73418.1 - 3.6e-07 30.1 0.0 0.00017 21.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCK73418.1 - 3.3e-05 24.0 0.0 7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCK73418.1 - 4.6e-05 22.6 0.0 9.7e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 CCK73418.1 - 9.4e-05 22.7 0.1 0.0004 20.6 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA PF00004.24 CCK73418.1 - 0.00038 20.6 0.0 0.0017 18.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCK73418.1 - 0.00058 19.8 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 CCK73418.1 - 0.00061 19.5 0.0 0.0013 18.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 CCK73418.1 - 0.00066 19.8 0.0 0.0018 18.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.15 CCK73418.1 - 0.00079 19.1 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase KTI12 PF08433.5 CCK73418.1 - 0.0011 18.2 0.0 0.002 17.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 T2SE PF00437.15 CCK73418.1 - 0.0011 17.9 0.0 0.0022 16.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PRK PF00485.13 CCK73418.1 - 0.0012 18.4 0.0 1.9 8.0 0.0 2.7 2 1 1 3 3 3 2 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 CCK73418.1 - 0.0013 18.6 0.0 0.0023 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 CCK73418.1 - 0.0029 17.3 0.0 0.0062 16.2 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 CCK73418.1 - 0.0038 16.4 0.0 0.0062 15.7 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.18 CCK73418.1 - 0.0039 17.1 0.0 0.0085 16.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_19 PF13245.1 CCK73418.1 - 0.0045 16.7 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 CCK73418.1 - 0.0067 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_14 PF13173.1 CCK73418.1 - 0.0076 16.1 0.0 0.024 14.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain DNA_pol3_delta2 PF13177.1 CCK73418.1 - 0.0084 15.7 0.1 0.079 12.6 0.0 2.1 2 1 0 2 2 2 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 CCK73418.1 - 0.0094 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activ_2 PF14532.1 CCK73418.1 - 0.01 15.8 0.0 0.021 14.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.1 CCK73418.1 - 0.011 15.0 0.0 0.074 12.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCK73418.1 - 0.012 15.0 0.0 0.059 12.9 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CCK73418.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 CCK73418.1 - 0.015 14.1 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain DUF2075 PF09848.4 CCK73418.1 - 0.017 14.1 0.0 0.027 13.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 CCK73418.1 - 0.018 14.4 0.0 0.034 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Rad17 PF03215.10 CCK73418.1 - 0.02 13.6 0.0 0.033 12.8 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein 6PF2K PF01591.13 CCK73418.1 - 0.022 13.8 0.0 0.048 12.7 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA_24 PF13479.1 CCK73418.1 - 0.023 14.2 0.0 0.05 13.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 CCK73418.1 - 0.023 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_30 PF13604.1 CCK73418.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CCK73418.1 - 0.029 13.0 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus DUF258 PF03193.11 CCK73418.1 - 0.034 13.3 0.1 0.092 11.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SRPRB PF09439.5 CCK73418.1 - 0.042 13.0 0.0 0.078 12.1 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_10 PF12846.2 CCK73418.1 - 0.046 13.1 0.0 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain KAP_NTPase PF07693.9 CCK73418.1 - 0.048 12.6 0.0 0.061 12.3 0.0 1.4 2 0 0 2 2 1 0 KAP family P-loop domain Viral_helicase1 PF01443.13 CCK73418.1 - 0.05 13.1 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ArgK PF03308.11 CCK73418.1 - 0.059 12.1 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Miro PF08477.8 CCK73418.1 - 0.068 13.6 0.0 0.19 12.2 0.0 1.8 2 0 0 2 2 1 0 Miro-like protein Cytidylate_kin2 PF13189.1 CCK73418.1 - 0.069 13.0 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 1 0 Cytidylate kinase-like family ADK PF00406.17 CCK73418.1 - 0.071 12.9 0.0 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 Adenylate kinase cobW PF02492.14 CCK73418.1 - 0.086 12.2 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SKI PF01202.17 CCK73418.1 - 0.096 12.5 0.0 0.26 11.1 0.0 1.7 2 0 0 2 2 1 0 Shikimate kinase SRP54 PF00448.17 CCK73418.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PPV_E1_C PF00519.12 CCK73418.1 - 0.12 10.9 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Sigma54_activat PF00158.21 CCK73418.1 - 0.16 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Bunya_G2 PF03563.8 CCK73418.1 - 0.17 10.7 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 AAA_23 PF13476.1 CCK73418.1 - 0.35 11.1 3.9 0.78 10.0 2.7 2.1 1 1 0 1 1 1 0 AAA domain Thioredoxin PF00085.15 CCK73419.1 - 1.5e-11 43.8 0.1 3.9e-11 42.5 0.1 1.7 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CCK73419.1 - 0.00013 22.0 0.5 0.0004 20.4 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CCK73419.1 - 0.0024 18.0 0.1 0.0051 16.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain PLDc_2 PF13091.1 CCK73420.1 - 9.3e-14 51.2 0.0 1.8e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CCK73420.1 - 2.6e-08 33.4 2.5 0.0017 18.0 0.1 2.8 2 1 0 2 2 2 2 Phospholipase D Active site motif PQ-loop PF04193.9 CCK73421.1 - 2.3e-06 27.0 9.2 2.3e-06 27.0 6.4 4.2 4 1 0 4 4 4 2 PQ loop repeat Rer1 PF03248.8 CCK73422.1 - 1.2e-73 246.4 8.0 1.4e-73 246.2 5.5 1.0 1 0 0 1 1 1 1 Rer1 family DUF4395 PF14340.1 CCK73422.1 - 0.028 14.4 1.7 4.4 7.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) eRF1_2 PF03464.10 CCK73423.1 - 2.8e-31 108.6 0.3 4.9e-31 107.8 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CCK73423.1 - 2.7e-22 79.1 0.0 7.2e-22 77.7 0.0 1.8 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CCK73423.1 - 1.2e-11 44.3 0.4 2.3e-11 43.3 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 1 PhosphMutase PF10143.4 CCK73423.1 - 0.039 13.6 0.1 0.091 12.4 0.1 1.6 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase RNA12 PF10443.4 CCK73423.1 - 0.04 12.4 1.6 0.049 12.1 0.8 1.4 1 1 0 1 1 1 0 RNA12 protein Ribosomal_L32p PF01783.18 CCK73424.1 - 6.1e-13 48.7 4.7 1.2e-12 47.7 3.3 1.5 1 0 0 1 1 1 1 Ribosomal L32p protein family FMN_red PF03358.10 CCK73425.1 - 8.1e-10 38.4 0.0 1.3e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 CCK73425.1 - 2.3e-08 34.1 0.4 5.9e-08 32.8 0.0 1.9 2 1 1 3 3 3 1 Flavodoxin Flavodoxin_2 PF02525.12 CCK73425.1 - 0.00068 19.1 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin-like fold Citrate_synt PF00285.16 CCK73426.1 - 1.2e-100 336.7 0.0 1.5e-100 336.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase DSPc PF00782.15 CCK73427.1 - 3.8e-27 94.4 0.5 6e-26 90.6 0.4 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCK73427.1 - 2e-05 24.0 0.0 3.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCK73427.1 - 0.0001 22.3 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Yippee-Mis18 PF03226.9 CCK73427.1 - 0.0092 15.9 0.9 0.066 13.2 0.6 2.3 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Elf1 PF05129.8 CCK73427.1 - 0.043 13.5 0.6 3.2 7.4 0.0 2.7 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like Apc15p PF05841.6 CCK73428.1 - 3.5e-15 56.8 0.1 3.5e-15 56.8 0.1 4.7 5 0 0 5 5 5 1 Apc15p protein DUF4145 PF13643.1 CCK73428.1 - 0.028 14.2 0.0 0.095 12.5 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) AMP-binding_C_2 PF14535.1 CCK73428.1 - 0.032 14.2 0.1 0.11 12.5 0.0 1.9 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain Mitofilin PF09731.4 CCK73428.1 - 0.2 10.2 14.6 0.017 13.7 6.6 1.8 3 0 0 3 3 3 0 Mitochondrial inner membrane protein Npa1 PF11707.3 CCK73429.1 - 3.6e-90 302.3 8.8 3.6e-90 302.3 6.1 3.7 4 0 0 4 4 4 1 Ribosome 60S biogenesis N-terminal HTH_6 PF01418.12 CCK73430.1 - 0.13 12.0 1.1 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family DUF848 PF05852.6 CCK73430.1 - 3.1 7.6 9.1 0.37 10.6 1.1 2.4 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF2762 PF10960.3 CCK73430.1 - 3.2 7.5 6.5 17 5.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) TMF_TATA_bd PF12325.3 CCK73430.1 - 4.1 7.1 10.5 1 9.1 0.2 2.8 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fungal_trans PF04082.13 CCK73431.1 - 4.7e-23 81.3 3.4 4.7e-23 81.3 2.4 3.6 4 0 0 4 4 4 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 CCK73432.1 - 5.8e-165 549.2 38.9 6.7e-165 549.0 27.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCK73432.1 - 2.1e-28 99.0 40.1 5.6e-28 97.6 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCK73432.1 - 0.00026 19.2 3.3 0.00026 19.2 2.3 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector SUR7 PF06687.7 CCK73433.1 - 3.3e-25 88.8 10.2 4.6e-25 88.4 7.1 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF2207 PF09972.4 CCK73433.1 - 0.18 10.3 1.7 0.29 9.6 1.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) WBP-1 PF11669.3 CCK73433.1 - 0.19 11.8 3.9 0.22 11.5 1.3 2.3 1 1 1 2 2 2 0 WW domain-binding protein 1 L_HGMIC_fpl PF10242.4 CCK73433.1 - 0.67 9.9 0.0 0.67 9.9 0.0 2.5 1 1 2 3 3 3 0 Lipoma HMGIC fusion partner-like protein Tht1 PF04163.7 CCK73435.1 - 4e-13 48.6 43.7 3.2e-11 42.3 30.3 2.2 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein Baculo_PEP_C PF04513.7 CCK73435.1 - 3.3 7.5 15.1 0.51 10.1 3.6 2.8 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus SURF6 PF04935.7 CCK73436.1 - 3.6e-48 163.6 54.5 3.6e-48 163.6 37.8 3.9 2 2 1 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 CCK73436.1 - 3.6e-18 65.3 2.3 3.6e-18 65.3 1.6 7.6 7 2 0 7 7 7 1 60S ribosome biogenesis protein Rrp14 TUG-UBL1 PF11470.3 CCK73438.1 - 7.1e-18 64.2 0.4 2.4e-17 62.6 0.1 2.1 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 CCK73438.1 - 1.6e-11 44.0 0.2 6e-11 42.2 0.0 2.0 2 0 0 2 2 2 1 UBX domain CENP-T PF15511.1 CCK73438.1 - 0.4 9.8 18.8 0.014 14.7 8.9 1.6 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 CCK73438.1 - 1.1 7.2 26.4 0.0054 14.8 12.2 1.5 2 0 0 2 2 2 0 CDC45-like protein AIF_C PF14721.1 CCK73438.1 - 8.1 6.6 10.0 0.8 9.9 2.3 2.3 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Nop14 PF04147.7 CCK73438.1 - 9.1 4.0 34.9 0.045 11.6 17.7 1.7 2 0 0 2 2 2 0 Nop14-like family Ank_2 PF12796.2 CCK73439.1 - 3.6e-32 110.5 4.9 2.5e-14 53.3 0.3 3.7 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCK73439.1 - 6.6e-23 80.6 3.5 6.2e-08 32.9 0.2 3.6 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CCK73439.1 - 6.2e-22 76.2 9.6 1.1e-07 31.2 0.2 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 CCK73439.1 - 2.1e-13 49.1 10.3 0.0013 18.7 0.1 5.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 CCK73439.1 - 7.8e-08 32.3 11.4 0.00016 21.8 0.1 4.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) G-alpha PF00503.15 CCK73440.1 - 2.7e-116 388.4 13.3 3.8e-116 387.9 9.2 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCK73440.1 - 9.3e-16 57.5 0.4 2.9e-10 39.6 0.0 2.8 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCK73440.1 - 0.00071 18.7 0.7 0.18 10.9 0.1 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 CCK73440.1 - 0.00088 19.7 1.6 0.48 10.9 0.0 3.2 3 0 0 3 3 3 2 Miro-like protein GTP_EFTU PF00009.22 CCK73440.1 - 0.046 13.1 0.0 1.8 7.9 0.0 2.6 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCK73440.1 - 0.049 13.5 0.0 10 6.0 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_29 PF13555.1 CCK73440.1 - 0.092 12.2 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MutS_V PF00488.16 CCK73440.1 - 0.11 11.9 0.0 0.29 10.4 0.0 1.7 2 0 0 2 2 2 0 MutS domain V MMR_HSR1 PF01926.18 CCK73441.1 - 3.2e-12 46.4 1.3 5.4e-11 42.4 0.2 2.7 2 2 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCK73441.1 - 9.2e-05 21.9 3.6 0.0003 20.2 0.6 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain KTI12 PF08433.5 CCK73441.1 - 0.0019 17.4 0.3 0.016 14.4 0.0 2.3 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 CCK73441.1 - 0.0021 18.8 0.1 0.016 16.0 0.0 2.4 2 2 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CCK73441.1 - 0.0041 17.4 3.0 0.0054 17.0 0.0 2.7 3 1 0 3 3 3 1 AAA domain DUF258 PF03193.11 CCK73441.1 - 0.0079 15.4 0.7 0.056 12.6 0.5 2.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 CCK73441.1 - 0.013 14.5 0.0 0.013 14.5 0.0 1.9 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 CCK73441.1 - 0.027 13.9 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CCK73441.1 - 0.035 13.5 0.0 0.08 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 CCK73441.1 - 0.043 13.5 0.1 0.093 12.4 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 CCK73441.1 - 0.075 13.5 1.9 1.2 9.6 0.1 2.9 3 0 0 3 3 3 0 Miro-like protein Dynamin_N PF00350.18 CCK73441.1 - 0.15 11.8 6.1 1.3 8.8 0.1 3.5 3 1 0 3 3 3 0 Dynamin family Secretin_N_2 PF07655.8 CCK73441.1 - 5.7 7.4 18.3 1.1 9.7 4.6 2.8 3 0 0 3 3 3 0 Secretin N-terminal domain zf-Tim10_DDP PF02953.10 CCK73442.1 - 2e-24 84.6 3.6 2.4e-24 84.4 2.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CCK73442.1 - 0.012 15.0 2.8 0.015 14.7 2.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) YopD PF05844.7 CCK73442.1 - 0.11 11.4 0.2 0.14 11.2 0.2 1.0 1 0 0 1 1 1 0 YopD protein Y_phosphatase PF00102.22 CCK73443.1 - 0.054 12.8 1.3 0.1 11.9 0.9 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase NuA4 PF09340.5 CCK73443.1 - 0.29 10.7 3.9 1.2 8.8 0.0 3.2 5 0 0 5 5 5 0 Histone acetyltransferase subunit NuA4 Ydc2-catalyt PF09159.5 CCK73444.1 - 1.7e-15 57.2 1.0 1.7e-15 57.2 0.7 2.0 2 1 0 2 2 2 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 FF PF01846.14 CCK73445.1 - 6.1e-30 102.9 35.6 3.6e-13 49.2 1.8 6.4 7 0 0 7 7 7 4 FF domain WW PF00397.21 CCK73445.1 - 1.5e-16 59.9 5.8 2e-08 33.9 0.2 2.6 2 0 0 2 2 2 2 WW domain ArgJ PF01960.13 CCK73446.1 - 1.7e-145 484.3 6.1 1.9e-145 484.1 4.2 1.0 1 0 0 1 1 1 1 ArgJ family Suf PF05843.9 CCK73447.1 - 7.6e-70 235.8 8.0 7.6e-70 235.8 5.5 4.3 3 1 1 4 4 4 3 Suppressor of forked protein (Suf) Tom37_C PF11801.3 CCK73448.1 - 9.3e-31 106.9 5.3 1.4e-30 106.3 3.7 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 CCK73448.1 - 7.3e-17 61.3 0.0 1.6e-16 60.2 0.0 1.6 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Cu-oxidase_2 PF07731.9 CCK73450.1 - 5.2e-42 142.6 7.1 5.9e-39 132.7 0.5 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CCK73450.1 - 1.8e-41 140.5 10.1 2.9e-39 133.4 0.4 3.4 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 CCK73450.1 - 1.4e-35 122.5 7.7 2.1e-32 112.2 1.2 3.5 3 1 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 CCK73450.1 - 0.004 17.0 0.5 0.44 10.4 0.0 3.5 4 0 0 4 4 4 1 Cupredoxin-like domain C1q PF00386.16 CCK73450.1 - 0.026 14.5 0.0 0.081 12.9 0.0 1.8 1 0 0 1 1 1 0 C1q domain DUF3364 PF11844.3 CCK73450.1 - 0.043 13.8 2.5 5.6 7.0 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3364) Glycophorin_A PF01102.13 CCK73450.1 - 0.17 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 Glycophorin A Mito_carr PF00153.22 CCK73451.1 - 4.3e-70 231.5 4.0 1.2e-23 82.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RabGAP-TBC PF00566.13 CCK73452.1 - 3e-32 111.8 5.3 2.9e-24 85.7 1.3 2.1 2 0 0 2 2 2 2 Rab-GTPase-TBC domain V_ATPase_I PF01496.14 CCK73453.1 - 1.5e-282 938.9 1.1 1.8e-282 938.8 0.7 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF2884 PF11101.3 CCK73453.1 - 0.04 13.2 0.1 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2884) Gp-FAR-1 PF05823.7 CCK73453.1 - 0.14 12.1 0.3 13 5.6 0.0 3.3 2 2 0 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF3450 PF11932.3 CCK73454.1 - 0.3 10.3 7.6 0.65 9.2 5.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) rve PF00665.21 CCK73455.1 - 2.1e-19 69.7 0.0 6.2e-19 68.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.22 CCK73455.1 - 7.9e-12 44.9 1.2 1.5e-11 44.0 0.0 2.1 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP PF00077.15 CCK73455.1 - 0.00032 20.5 0.4 0.0015 18.4 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 CCK73455.1 - 0.0022 17.7 0.0 0.0064 16.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 CCK73455.1 - 0.023 14.0 1.8 0.1 11.9 0.0 2.7 3 0 0 3 3 3 0 Ty3 transposon peptidase Asp_protease_2 PF13650.1 CCK73455.1 - 0.034 14.6 0.0 0.13 12.7 0.0 2.1 1 0 0 1 1 1 0 Aspartyl protease Vps55 PF04133.9 CCK73456.1 - 3.5e-44 149.3 8.8 4.1e-44 149.1 6.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2085 PF09858.4 CCK73456.1 - 0.024 14.6 0.1 0.024 14.6 0.1 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) DUF2108 PF09881.4 CCK73456.1 - 0.28 11.0 4.2 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2108) DUF1056 PF06341.6 CCK73456.1 - 0.5 10.4 0.2 0.5 10.4 0.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1056) DUF4018 PF13210.1 CCK73456.1 - 2.2 7.6 8.8 0.24 10.7 1.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) DUF2614 PF11023.3 CCK73456.1 - 2.5 7.9 5.2 1.8 8.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2614) DUF1049 PF06305.6 CCK73456.1 - 7.4 6.1 9.2 0.71 9.3 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1049) HSP70 PF00012.15 CCK73457.1 - 1.6e-266 885.0 15.3 1.9e-266 884.8 10.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCK73457.1 - 2e-15 56.2 2.8 2.8e-13 49.1 0.7 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CCK73457.1 - 0.0024 17.5 0.0 0.0058 16.2 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF2797 PF10977.3 CCK73457.1 - 0.0044 16.6 3.2 0.0088 15.6 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2797) Gp-FAR-1 PF05823.7 CCK73457.1 - 0.035 14.0 7.3 0.083 12.8 5.0 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Prp18 PF02840.10 CCK73457.1 - 0.11 12.3 1.6 2.8 7.7 1.9 2.4 2 0 0 2 2 2 0 Prp18 domain FtsA PF14450.1 CCK73457.1 - 0.13 12.0 15.4 2.3 8.0 0.4 4.8 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.13 CCK73457.1 - 1.2 8.2 9.6 0.18 10.8 0.1 3.3 3 1 0 4 4 4 0 Hydantoinase/oxoprolinase Nucleoporin2 PF04096.9 CCK73459.1 - 1e-43 148.5 2.7 2.1e-43 147.4 0.0 2.5 2 0 0 2 2 2 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CCK73459.1 - 5.9e-40 136.0 315.4 2.6e-12 46.9 34.8 9.0 3 2 7 10 10 10 7 Nucleoporin FG repeat region Swi3 PF07962.7 CCK73460.1 - 1.9e-24 85.1 0.5 1.9e-24 85.1 0.3 1.9 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 BUD22 PF09073.5 CCK73460.1 - 0.86 8.6 24.5 1.3 8.0 17.0 1.1 1 0 0 1 1 1 0 BUD22 Tir_receptor_C PF07489.6 CCK73460.1 - 6.3 6.4 13.1 15 5.2 9.0 1.6 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus TINF2_N PF14973.1 CCK73461.1 - 0.077 13.1 2.7 0.16 12.0 1.8 1.5 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus DUF3154 PF11351.3 CCK73461.1 - 0.35 10.6 1.9 0.61 9.8 0.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Urb2 PF10441.4 CCK73462.1 - 2.8e-57 193.9 3.9 1.2e-56 191.8 2.7 2.1 1 0 0 1 1 1 1 Urb2/Npa2 family DUF1133 PF06576.6 CCK73462.1 - 0.065 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1133) Voltage_CLC PF00654.15 CCK73463.1 - 1.9e-78 264.0 23.2 3e-78 263.3 16.1 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 CCK73463.1 - 5.6e-09 35.6 0.0 0.0004 20.1 0.0 2.6 2 0 0 2 2 2 2 CBS domain Ribosomal_L7Ae PF01248.21 CCK73464.1 - 2.9e-26 90.7 0.1 3.5e-26 90.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CCK73464.1 - 0.01 15.7 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 PELOTA_1 PF15608.1 CCK73464.1 - 0.084 12.6 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 PELOTA RNA binding domain HECT PF00632.20 CCK73466.1 - 1.7e-85 286.9 4.8 1.7e-85 286.9 3.3 1.9 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SNF2_N PF00176.18 CCK73467.1 - 2.3e-74 249.8 0.2 4.8e-74 248.8 0.1 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCK73467.1 - 1.1e-15 57.2 0.0 4e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_11 PF13086.1 CCK73467.1 - 0.12 11.9 0.1 0.12 11.9 0.0 3.7 4 2 0 4 4 4 0 AAA domain Pet191_N PF10203.4 CCK73468.1 - 2e-25 88.5 4.3 2.7e-25 88.1 3.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 CCK73468.1 - 0.038 13.9 1.6 0.67 9.9 0.2 2.6 2 0 0 2 2 2 0 CHCH domain Cmc1 PF08583.5 CCK73468.1 - 0.047 13.4 0.8 4.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Rav1p_C PF12234.3 CCK73469.1 - 1.3e-249 829.6 3.3 1.9e-249 829.1 2.3 1.3 1 0 0 1 1 1 1 RAVE protein 1 C terminal WD40 PF00400.27 CCK73469.1 - 2.3e-10 39.9 4.4 0.0014 18.4 0.0 4.8 3 1 0 3 3 3 2 WD domain, G-beta repeat Pro_isomerase PF00160.16 CCK73470.1 - 2.8e-42 144.5 0.3 4.3e-42 143.9 0.2 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CCK73470.1 - 1.7e-13 49.9 3.1 1.3e-07 31.1 0.3 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CCK73470.1 - 8.6e-10 37.7 7.0 0.00014 21.5 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCK73470.1 - 3.9e-07 29.3 13.0 9.6e-05 21.8 0.5 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 CCK73470.1 - 2.4e-05 23.7 13.9 0.0035 17.0 0.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCK73470.1 - 8.8e-05 22.3 0.1 0.027 14.4 0.1 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCK73470.1 - 0.08 13.6 0.0 0.65 10.7 0.0 2.3 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CCK73470.1 - 2.5 8.2 8.3 93 3.2 5.6 2.8 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 ADH_N PF08240.7 CCK73471.1 - 1.8e-26 92.0 2.6 3.6e-26 91.0 1.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCK73471.1 - 3.2e-16 59.0 0.0 5.1e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCK73471.1 - 4e-06 26.1 0.1 7.2e-06 25.2 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CCK73471.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 CCK73471.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 CCK73471.1 - 0.1 12.4 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Aldo_ket_red PF00248.16 CCK73472.1 - 4.6e-60 202.8 0.0 5.2e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sec7 PF01369.15 CCK73473.1 - 6e-58 195.6 4.2 1.9e-57 194.0 2.9 1.9 1 0 0 1 1 1 1 Sec7 domain DUF2683 PF10884.3 CCK73473.1 - 0.02 14.8 4.1 0.18 11.7 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2683) tRNA-synt_2 PF00152.15 CCK73474.1 - 3.3e-68 229.9 0.0 4.5e-68 229.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCK73474.1 - 7.9e-07 28.8 0.0 1.6e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PIP49_C PF12260.3 CCK73474.1 - 0.027 13.9 0.0 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Phosphodiest PF01663.17 CCK73475.1 - 7.3e-33 114.3 5.4 7.3e-33 114.3 3.8 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase PI3K_1B_p101 PF10486.4 CCK73475.1 - 1.1 6.7 9.0 2 5.8 6.3 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Ras PF00071.17 CCK73476.1 - 1.3e-43 148.1 0.1 1.7e-43 147.8 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCK73476.1 - 2.5e-13 50.5 0.0 3.9e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCK73476.1 - 1.8e-11 43.5 0.4 2.2e-11 43.3 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCK73476.1 - 1.1e-05 24.9 0.6 0.00034 20.0 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCK73476.1 - 1.3e-05 25.0 0.2 2.2e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCK73476.1 - 0.0011 18.2 0.2 0.0014 17.8 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCK73476.1 - 0.013 14.2 0.1 2.8 6.5 0.0 2.1 1 1 1 2 2 2 0 G-protein alpha subunit MobB PF03205.9 CCK73476.1 - 0.04 13.6 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CCK73476.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PfkB PF00294.19 CCK73477.1 - 6.4e-08 32.0 0.0 7e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TENA_THI-4 PF03070.11 CCK73478.1 - 2.8e-15 56.6 2.3 3.5e-15 56.3 1.6 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family LSM PF01423.17 CCK73479.1 - 1e-07 31.3 0.0 1.5e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 LSM domain VARLMGL PF14383.1 CCK73479.1 - 0.062 12.4 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 DUF761-associated sequence motif DsbC_N PF10411.4 CCK73479.1 - 0.093 12.0 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus TEP1_N PF05386.6 CCK73480.1 - 0.084 12.3 0.1 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 TEP1 N-terminal domain Frag1 PF10277.4 CCK73481.1 - 3.2e-37 128.0 13.3 3.2e-37 128.0 9.2 3.9 2 1 2 4 4 4 1 Frag1/DRAM/Sfk1 family SRP1_TIP1 PF00660.12 CCK73482.1 - 4.5e-34 116.4 0.0 5.3e-34 116.1 0.0 1.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family DNA_pol_B_thumb PF14791.1 CCK73483.1 - 1.1e-16 60.2 0.1 4e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb HHH_8 PF14716.1 CCK73483.1 - 4.3e-14 52.4 0.5 1.2e-13 50.9 0.1 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_palm PF14792.1 CCK73483.1 - 4.8e-14 52.3 0.1 8.3e-13 48.3 0.0 2.6 3 0 0 3 3 3 1 DNA polymerase beta palm DNA_pol_lambd_f PF10391.4 CCK73483.1 - 3.8e-08 32.7 0.0 1.1e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.18 CCK73483.1 - 0.0064 16.7 0.1 0.021 15.1 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain PGK PF00162.14 CCK73484.1 - 1.5e-152 507.6 0.2 1.7e-152 507.4 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase ABC2_membrane PF01061.19 CCK73485.1 - 1.4e-36 125.6 19.6 1.4e-36 125.6 13.6 2.0 3 0 0 3 3 3 1 ABC-2 type transporter ABC_tran PF00005.22 CCK73485.1 - 1.3e-28 100.0 0.0 2.8e-28 98.9 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 CCK73485.1 - 0.00055 19.3 0.4 0.061 12.7 0.2 2.2 2 0 0 2 2 2 1 AAA domain hEGF PF12661.2 CCK73485.1 - 0.0034 17.3 10.1 0.051 13.6 1.5 3.4 2 0 0 2 2 2 2 Human growth factor-like EGF DUF258 PF03193.11 CCK73485.1 - 0.0055 15.9 0.2 0.014 14.6 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCK73485.1 - 0.0083 15.6 0.4 0.027 13.9 0.2 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 CCK73485.1 - 0.01 15.7 0.1 0.018 15.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain EGF_2 PF07974.8 CCK73485.1 - 0.013 15.6 6.7 0.013 15.6 4.7 4.8 4 0 0 4 4 4 0 EGF-like domain AAA_22 PF13401.1 CCK73485.1 - 0.016 15.3 0.5 0.06 13.4 0.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCK73485.1 - 0.017 15.1 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SbcCD_C PF13558.1 CCK73485.1 - 0.04 13.8 0.0 0.098 12.5 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 CCK73485.1 - 0.08 13.7 0.3 0.32 11.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_pol_Rpc34 PF05158.7 CCK73486.1 - 3.2e-95 319.0 0.1 3.9e-95 318.7 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.15 CCK73486.1 - 0.012 15.7 0.1 0.022 14.8 0.1 1.4 1 0 0 1 1 1 0 Transcriptional regulator TrmB PF01978.14 CCK73486.1 - 0.029 14.0 0.9 8.1 6.2 0.2 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB B-block_TFIIIC PF04182.7 CCK73486.1 - 0.035 13.9 2.5 0.16 11.7 0.1 2.4 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC SUA5 PF03481.8 CCK73486.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding Grp1_Fun34_YaaH PF01184.14 CCK73487.1 - 2.3e-91 304.7 18.5 2.7e-91 304.5 12.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BAR PF03114.13 CCK73488.1 - 6.4e-53 179.6 1.6 7.5e-53 179.3 1.1 1.0 1 0 0 1 1 1 1 BAR domain MgtE_N PF03448.12 CCK73488.1 - 0.029 14.6 0.1 0.23 11.8 0.0 2.4 2 1 0 2 2 2 0 MgtE intracellular N domain DUF4164 PF13747.1 CCK73488.1 - 0.27 11.4 4.6 0.95 9.6 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Seryl_tRNA_N PF02403.17 CCK73488.1 - 0.4 10.7 4.7 4.7 7.2 0.7 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.20 CCK73489.1 - 3.4e-60 203.3 0.1 3.4e-60 203.3 0.1 3.9 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCK73489.1 - 3.9e-22 78.5 0.5 7.7e-21 74.3 0.0 2.6 2 1 1 3 3 3 1 Protein tyrosine kinase Kdo PF06293.9 CCK73489.1 - 0.0013 17.7 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCK73489.1 - 0.017 14.0 0.0 0.048 12.6 0.0 1.7 1 0 0 1 1 1 0 Kinase-like Stap_Strp_toxin PF01123.15 CCK73489.1 - 0.028 14.8 0.9 0.028 14.8 0.6 3.7 2 1 1 3 3 3 0 Staphylococcal/Streptococcal toxin, OB-fold domain HRXXH PF13933.1 CCK73490.1 - 0.084 12.2 3.7 0.13 11.6 2.6 1.3 1 0 0 1 1 1 0 Putative peptidase family BAF1_ABF1 PF04684.8 CCK73490.1 - 0.24 10.1 15.4 0.2 10.4 9.9 1.6 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 CCK73490.1 - 0.67 8.0 25.2 0.87 7.7 17.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 CCK73490.1 - 2.8 7.7 21.2 3.7 7.3 14.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hep_59 PF07052.6 CCK73490.1 - 2.9 8.3 16.7 0.61 10.4 6.5 2.3 2 0 0 2 2 2 0 Hepatocellular carcinoma-associated antigen 59 EphA2_TM PF14575.1 CCK73490.1 - 6.6 7.2 5.7 20 5.6 4.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain adh_short PF00106.20 CCK73491.1 - 6.7e-30 104.1 0.0 8.9e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCK73491.1 - 8.9e-19 68.2 0.1 1.1e-18 67.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCK73491.1 - 2.7e-11 43.4 0.0 4.1e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCK73491.1 - 6.8e-06 25.6 0.1 1.2e-05 24.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCK73491.1 - 0.00043 20.3 0.0 0.00056 19.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCK73491.1 - 0.0037 16.0 0.1 0.0047 15.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 CCK73491.1 - 0.0079 15.1 0.1 0.012 14.5 0.1 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein PP2C_2 PF13672.1 CCK73491.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 2C TrkA_N PF02254.13 CCK73491.1 - 0.13 12.2 0.6 0.25 11.3 0.1 1.6 2 0 0 2 2 2 0 TrkA-N domain AlaDh_PNT_N PF05222.10 CCK73492.1 - 1.4e-29 102.8 0.0 2.1e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CCK73492.1 - 7.6e-15 54.8 0.0 1.1e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain DUF1900 PF08954.6 CCK73492.1 - 0.14 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) Ank PF00023.25 CCK73493.1 - 4.2e-13 48.3 0.0 3.7e-05 23.3 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CCK73493.1 - 2e-11 44.0 0.0 5.9e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCK73493.1 - 2.3e-10 40.6 0.6 3.9e-08 33.5 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCK73493.1 - 6.2e-08 32.6 0.1 1.6e-06 28.1 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCK73493.1 - 1.8e-07 30.6 0.1 0.019 15.1 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat MutS_V PF00488.16 CCK73494.1 - 3e-98 327.9 0.1 5e-98 327.2 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCK73494.1 - 7.8e-34 117.2 0.9 7.8e-34 117.2 0.6 2.5 3 0 0 3 3 3 1 MutS domain III MutS_II PF05188.12 CCK73494.1 - 1.5e-20 73.6 0.2 1.1e-19 70.8 0.1 2.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 CCK73494.1 - 1.3e-17 63.7 2.0 1.3e-17 63.7 1.4 2.3 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 CCK73494.1 - 5.8e-11 42.4 0.1 3.8e-10 39.7 0.0 2.3 3 0 0 3 3 3 1 MutS domain I PQ-loop PF04193.9 CCK73496.1 - 1.1e-41 140.1 14.5 3.1e-22 77.8 0.8 2.9 3 0 0 3 3 3 2 PQ loop repeat Steroid_dh PF02544.11 CCK73496.1 - 0.034 13.9 0.3 0.034 13.9 0.2 2.0 2 0 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase tRNA_m1G_MT PF01746.16 CCK73497.1 - 3.6e-38 131.0 0.5 5.4e-38 130.4 0.0 1.5 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase DUF1675 PF07897.6 CCK73497.1 - 1.6 8.5 4.7 3.1 7.6 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1675) Rep_fac_C PF08542.6 CCK73498.1 - 2.2e-17 62.8 0.2 1.1e-16 60.5 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA PF00004.24 CCK73498.1 - 4.2e-13 49.6 0.0 7.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CCK73498.1 - 4.5e-13 49.1 0.0 2.9e-10 40.0 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA_14 PF13173.1 CCK73498.1 - 6.4e-07 29.3 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 CCK73498.1 - 1.5e-06 27.2 0.0 0.0035 16.0 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CCK73498.1 - 4.4e-06 26.7 0.0 0.00014 21.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCK73498.1 - 6e-06 26.4 0.1 0.0023 18.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.6 CCK73498.1 - 1.9e-05 24.2 0.0 3.4e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 CCK73498.1 - 6.5e-05 22.5 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.7 CCK73498.1 - 0.00011 21.2 0.1 0.00045 19.3 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 CCK73498.1 - 0.001 18.2 0.1 0.012 14.7 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 CCK73498.1 - 0.0012 18.3 0.0 0.21 11.0 0.0 2.5 1 1 1 2 2 2 1 AAA-like domain DNA_pol3_delta PF06144.8 CCK73498.1 - 0.0032 17.0 0.2 0.0062 16.0 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit FtsK_SpoIIIE PF01580.13 CCK73498.1 - 0.0036 16.8 0.0 0.0065 15.9 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_19 PF13245.1 CCK73498.1 - 0.0052 16.4 0.0 0.015 15.0 0.0 1.8 2 0 0 2 2 1 1 Part of AAA domain NTPase_1 PF03266.10 CCK73498.1 - 0.006 16.3 0.1 0.12 12.0 0.0 2.4 1 1 1 2 2 2 1 NTPase ArgK PF03308.11 CCK73498.1 - 0.015 14.1 0.0 0.081 11.6 0.0 2.2 2 1 0 2 2 2 0 ArgK protein AAA_11 PF13086.1 CCK73498.1 - 0.078 12.5 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 CCK73498.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Iso_dh PF00180.15 CCK73499.1 - 1.9e-71 240.8 0.0 2.2e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EF-hand_7 PF13499.1 CCK73500.1 - 2.7e-05 24.2 1.1 2.7e-05 24.2 0.8 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.1 CCK73500.1 - 0.0041 16.6 0.7 0.065 12.8 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CCK73500.1 - 0.0099 15.1 1.5 0.57 9.6 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 CCK73500.1 - 0.14 12.0 2.5 6.4 6.9 0.2 2.6 2 0 0 2 2 2 0 EF-hand domain HABP4_PAI-RBP1 PF04774.10 CCK73500.1 - 3.4 8.2 6.6 0.7 10.4 0.7 2.1 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family ABC_tran PF00005.22 CCK73501.1 - 5.4e-44 149.8 0.0 5.4e-22 78.5 0.0 4.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCK73501.1 - 2.9e-17 63.5 0.1 0.0027 17.7 0.0 4.4 3 1 1 4 4 4 4 AAA domain SMC_N PF02463.14 CCK73501.1 - 2.7e-15 56.2 0.0 1.9e-06 27.2 0.0 3.9 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCK73501.1 - 1.2e-09 38.8 2.4 0.0014 19.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCK73501.1 - 3.2e-09 36.1 0.0 0.0021 17.5 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CCK73501.1 - 1.3e-08 35.0 0.1 0.00084 19.4 0.0 4.1 5 1 0 5 5 3 2 AAA domain DUF258 PF03193.11 CCK73501.1 - 2e-08 33.6 0.1 0.00013 21.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCK73501.1 - 2.6e-08 34.6 0.0 0.0064 17.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 CCK73501.1 - 2.9e-07 30.4 0.0 4.9e-05 23.2 0.0 2.7 2 0 0 2 2 2 1 Dynamin family AAA_10 PF12846.2 CCK73501.1 - 4.4e-07 29.6 0.2 0.16 11.4 0.0 3.9 4 0 0 4 4 4 2 AAA-like domain MMS19_C PF12460.3 CCK73501.1 - 6.4e-07 28.4 0.6 0.016 13.9 0.0 3.2 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal MMR_HSR1 PF01926.18 CCK73501.1 - 8.3e-07 28.9 0.0 0.0058 16.5 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 CCK73501.1 - 8.4e-07 29.0 0.0 0.0068 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 CCK73501.1 - 1.3e-06 28.8 0.0 0.028 14.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA PF00004.24 CCK73501.1 - 2.9e-06 27.5 1.4 1.1 9.5 0.0 4.5 4 1 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 CCK73501.1 - 4e-06 26.6 0.1 0.02 14.7 0.0 3.6 3 1 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 CCK73501.1 - 6.3e-06 26.1 0.0 0.091 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCK73501.1 - 9.1e-06 26.0 0.0 0.017 15.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.17 CCK73501.1 - 9.6e-06 25.7 0.0 0.11 12.7 0.0 2.9 2 0 0 2 2 2 2 RNA helicase MobB PF03205.9 CCK73501.1 - 2.2e-05 24.1 0.1 0.38 10.4 0.0 3.1 3 0 0 3 3 2 2 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CCK73501.1 - 3.8e-05 22.6 0.2 0.2 10.4 0.0 2.5 2 0 0 2 2 2 2 ArgK protein HEAT_2 PF13646.1 CCK73501.1 - 7.6e-05 22.9 3.5 0.024 14.9 0.1 3.7 1 1 2 3 3 3 2 HEAT repeats Arch_ATPase PF01637.13 CCK73501.1 - 0.00012 21.9 0.0 0.38 10.4 0.0 3.0 2 0 0 2 2 2 2 Archaeal ATPase MutS_V PF00488.16 CCK73501.1 - 0.0002 20.8 0.1 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 MutS domain V AAA_16 PF13191.1 CCK73501.1 - 0.00042 20.3 4.2 0.11 12.4 0.1 4.1 4 1 0 4 4 4 1 AAA ATPase domain ParcG PF10274.4 CCK73501.1 - 0.00057 19.8 0.8 0.67 9.8 0.2 2.9 2 1 1 3 3 3 1 Parkin co-regulated protein AAA_14 PF13173.1 CCK73501.1 - 0.00058 19.7 0.0 2.5 8.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 CCK73501.1 - 0.00094 19.0 4.8 0.29 10.9 0.0 4.0 4 0 0 4 4 3 1 Domain of unknown function DUF87 AAA_30 PF13604.1 CCK73501.1 - 0.001 18.6 0.1 1.9 8.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 CCK73501.1 - 0.001 18.7 0.0 0.76 9.4 0.0 2.8 3 0 0 3 3 2 1 NACHT domain CLASP_N PF12348.3 CCK73501.1 - 0.0013 18.1 3.2 0.26 10.6 0.3 2.8 1 1 1 2 2 2 1 CLASP N terminal cobW PF02492.14 CCK73501.1 - 0.0029 17.0 0.1 1.8 7.9 0.0 3.0 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain HEAT PF02985.17 CCK73501.1 - 0.0029 17.5 1.9 17 5.8 0.0 4.9 5 0 0 5 5 4 0 HEAT repeat PduV-EutP PF10662.4 CCK73501.1 - 0.0036 16.8 0.0 0.36 10.3 0.0 3.3 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation UME PF08064.8 CCK73501.1 - 0.0042 17.0 1.4 0.024 14.5 0.2 2.5 1 1 0 2 2 2 1 UME (NUC010) domain AAA_25 PF13481.1 CCK73501.1 - 0.0066 15.8 0.0 3.1 7.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CCK73501.1 - 0.013 14.9 0.4 2 7.8 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family T2SE PF00437.15 CCK73501.1 - 0.017 13.9 0.1 0.48 9.2 0.0 2.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Vac14_Fab1_bd PF12755.2 CCK73501.1 - 0.021 15.2 0.1 1.4 9.3 0.0 3.0 2 1 1 3 3 2 0 Vacuolar 14 Fab1-binding region Septin PF00735.13 CCK73501.1 - 0.024 13.6 0.2 1.3 7.9 0.0 2.5 3 0 0 3 3 2 0 Septin ATP_bind_1 PF03029.12 CCK73501.1 - 0.024 14.1 0.3 8.4 5.8 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein HEAT_EZ PF13513.1 CCK73501.1 - 0.026 15.0 7.3 1.5 9.4 0.4 4.8 5 1 0 5 5 4 0 HEAT-like repeat ATP-synt_ab PF00006.20 CCK73501.1 - 0.029 13.8 0.1 11 5.4 0.0 3.1 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain GTP_EFTU PF00009.22 CCK73501.1 - 0.037 13.4 0.0 8.5 5.7 0.0 2.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_19 PF13245.1 CCK73501.1 - 0.038 13.7 0.2 5.8 6.7 0.0 3.0 3 0 0 3 3 2 0 Part of AAA domain Zeta_toxin PF06414.7 CCK73501.1 - 0.039 13.0 0.1 8.9 5.3 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.16 CCK73501.1 - 0.057 12.5 0.3 1 8.4 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_13 PF13166.1 CCK73501.1 - 0.093 11.1 14.9 1.7 6.9 0.0 4.6 4 1 1 5 5 4 0 AAA domain Cnd1 PF12717.2 CCK73501.1 - 0.16 11.8 1.3 3.9 7.2 0.0 3.1 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 UNC45-central PF11701.3 CCK73501.1 - 0.24 11.0 2.2 0.37 10.4 0.6 1.9 1 1 0 1 1 1 0 Myosin-binding striated muscle assembly central Pkinase PF00069.20 CCK73502.1 - 2.4e-57 194.0 0.0 3.4e-56 190.2 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCK73502.1 - 4.3e-23 81.7 0.0 8.4e-19 67.6 0.0 2.6 2 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCK73502.1 - 7.5e-05 21.8 0.1 0.064 12.2 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CCK73502.1 - 0.001 18.1 0.0 0.0018 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SNF2_N PF00176.18 CCK73503.1 - 1.9e-46 158.2 0.0 8.7e-45 152.7 0.0 2.7 1 1 1 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CCK73503.1 - 1.3e-10 40.8 11.6 3.1e-10 39.6 8.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCK73503.1 - 2.3e-08 33.8 12.9 6.5e-08 32.4 8.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCK73503.1 - 5.3e-08 32.4 9.8 1.1e-07 31.3 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCK73503.1 - 1.6e-06 27.6 12.0 4.3e-06 26.2 8.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCK73503.1 - 3e-06 26.8 12.3 8e-06 25.4 8.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CCK73503.1 - 4.3e-06 26.7 6.0 1.4e-05 25.0 4.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CCK73503.1 - 5.2e-05 22.8 4.0 7.9e-05 22.2 1.1 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCK73503.1 - 0.0014 18.4 12.1 0.0014 18.4 8.4 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 CCK73503.1 - 0.0024 17.3 5.9 0.0066 15.9 4.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CCK73503.1 - 0.0029 17.3 4.8 0.016 14.9 3.3 2.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 CCK73503.1 - 0.13 12.1 5.0 0.33 10.8 3.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Clat_adaptor_s PF01217.15 CCK73504.1 - 5.3e-54 181.8 0.8 6.1e-54 181.6 0.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SPG48 PF14764.1 CCK73504.1 - 0.079 11.4 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking TP_methylase PF00590.15 CCK73505.1 - 7e-24 84.6 0.0 1e-23 84.1 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 CCK73505.1 - 0.028 14.1 0.0 0.06 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) Pmp3 PF01679.12 CCK73507.1 - 5.4e-18 64.4 38.0 1e-06 28.3 4.1 4.4 4 0 0 4 4 4 4 Proteolipid membrane potential modulator ABC1 PF03109.11 CCK73508.1 - 1e-29 102.9 0.0 2e-29 101.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CCK73508.1 - 3.2e-05 23.3 0.0 8e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Zn_clus PF00172.13 CCK73509.1 - 5e-08 32.7 8.4 9.2e-08 31.8 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spc7 PF08317.6 CCK73511.1 - 0.00081 18.1 19.8 0.00081 18.1 13.7 1.8 1 1 1 2 2 2 1 Spc7 kinetochore protein Tropomyosin_1 PF12718.2 CCK73511.1 - 0.017 14.9 20.2 0.016 15.0 13.4 1.4 1 1 0 1 1 1 0 Tropomyosin like Tropomyosin PF00261.15 CCK73511.1 - 0.034 13.2 19.4 0.068 12.2 13.4 1.4 1 1 0 1 1 1 0 Tropomyosin TPR_MLP1_2 PF07926.7 CCK73511.1 - 0.043 13.5 14.6 0.075 12.7 10.1 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 CCK73511.1 - 0.072 12.1 12.5 0.11 11.5 8.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 PspA_IM30 PF04012.7 CCK73511.1 - 0.14 11.4 10.3 0.064 12.6 2.4 2.7 1 1 2 3 3 3 0 PspA/IM30 family DUF2730 PF10805.3 CCK73511.1 - 0.19 11.4 8.6 1.7 8.3 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) IMD PF08397.6 CCK73511.1 - 0.3 10.3 8.8 0.46 9.7 6.0 1.4 1 1 0 1 1 1 0 IRSp53/MIM homology domain Mod_r PF07200.8 CCK73511.1 - 0.3 11.0 16.9 0.18 11.7 6.1 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein SlyX PF04102.7 CCK73511.1 - 0.31 11.4 12.2 0.15 12.4 4.7 2.7 1 1 2 3 3 3 0 SlyX DUF745 PF05335.8 CCK73511.1 - 1.4 8.4 5.2 0.56 9.6 1.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF745) CENP-F_leu_zip PF10473.4 CCK73511.1 - 1.9 8.3 24.2 19 5.1 16.5 2.1 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4140 PF13600.1 CCK73511.1 - 2.7 8.5 6.1 1.9e+02 2.5 4.3 2.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) IncA PF04156.9 CCK73511.1 - 5.2 6.6 21.4 47 3.4 14.7 2.2 1 1 0 1 1 1 0 IncA protein DUF2203 PF09969.4 CCK73511.1 - 6.1 7.0 7.1 20 5.4 4.9 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Fmp27_WPPW PF10359.4 CCK73511.1 - 6.6 5.0 14.5 19 3.5 10.0 1.7 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF972 PF06156.8 CCK73511.1 - 9.5 6.6 20.4 0.32 11.3 5.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Glycogen_syn PF05693.8 CCK73512.1 - 0 1115.7 0.0 0 1115.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CCK73512.1 - 1.1e-09 38.0 0.0 5.1e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCK73512.1 - 3.3e-05 24.0 0.0 6.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 CCK73512.1 - 0.00027 20.5 0.1 0.00061 19.3 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Pkinase PF00069.20 CCK73513.1 - 3.5e-71 239.4 0.0 5.1e-71 238.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCK73513.1 - 2.1e-39 135.1 0.0 3.4e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CCK73513.1 - 0.0072 15.6 0.3 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 CCK73513.1 - 0.017 14.1 0.2 0.27 10.1 0.1 2.4 2 1 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.6 CCK73513.1 - 0.031 13.0 0.2 0.047 12.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase APH PF01636.18 CCK73513.1 - 0.15 11.7 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TMF_DNA_bd PF12329.3 CCK73513.1 - 1.1 9.1 6.7 4.4 7.1 0.4 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1086 PF06461.6 CCK73514.1 - 0.023 14.5 0.0 0.077 12.7 0.0 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1086) SNARE PF05739.14 CCK73515.1 - 3.4e-17 61.8 2.4 9.9e-17 60.3 1.1 2.2 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 CCK73515.1 - 2.9e-06 27.3 0.1 2.9e-06 27.3 0.1 2.8 1 1 1 2 2 2 1 Syntaxin SUR7 PF06687.7 CCK73516.1 - 1.2e-20 74.0 20.7 2e-20 73.2 14.3 1.3 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 CCK73516.1 - 0.0072 16.2 2.5 0.0072 16.2 1.7 1.8 1 1 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 WD40 PF00400.27 CCK73517.1 - 7.3e-38 127.1 13.0 1.9e-10 40.2 0.5 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CCK73517.1 - 9.9e-07 27.2 5.3 0.0045 15.1 0.1 4.2 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Jnk-SapK_ap_N PF09744.4 CCK73517.1 - 0.00032 20.7 4.4 0.00032 20.7 3.1 1.8 2 0 0 2 2 2 1 JNK_SAPK-associated protein-1 PQQ_2 PF13360.1 CCK73517.1 - 0.013 14.9 0.2 0.65 9.4 0.1 2.4 2 0 0 2 2 2 0 PQQ-like domain DUF3249 PF11615.3 CCK73517.1 - 0.046 13.4 0.0 2.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3249) YflT PF11181.3 CCK73517.1 - 0.45 10.7 10.4 0.073 13.2 0.7 3.0 2 1 1 3 3 3 0 Heat induced stress protein YflT GATA PF00320.22 CCK73518.1 - 1.3e-13 49.9 3.9 1.3e-13 49.9 2.7 2.3 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CCK73518.1 - 0.01 15.1 0.2 0.029 13.7 0.1 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding MFP2b PF12150.3 CCK73518.1 - 0.033 12.8 0.0 0.058 12.0 0.0 1.3 1 0 0 1 1 1 0 Cytosolic motility protein BP28CT PF08146.7 CCK73519.1 - 2.6e-43 147.4 5.3 2.6e-43 147.4 3.7 3.8 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 CCK73519.1 - 1.3e-19 70.3 1.7 1.3e-19 70.3 1.2 4.5 5 0 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 CCK73519.1 - 2.4e-05 24.5 0.1 5.4 7.3 0.0 5.0 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.17 CCK73519.1 - 0.00061 19.6 1.8 1.6 8.9 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 CCK73519.1 - 0.017 15.5 0.1 1.7 9.2 0.0 3.7 2 0 0 2 2 2 0 HEAT-like repeat Pkinase PF00069.20 CCK73520.1 - 1.1e-51 175.5 0.0 4.8e-50 170.1 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCK73520.1 - 2.1e-24 85.9 0.1 9.1e-23 80.6 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase SET PF00856.23 CCK73521.1 - 1.9e-05 24.9 1.3 1.9e-05 24.9 0.9 3.1 2 1 0 2 2 2 1 SET domain AlaDh_PNT_C PF01262.16 CCK73521.1 - 0.47 10.0 1.6 0.72 9.3 0.4 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PHD PF00628.24 CCK73521.1 - 1.6 8.4 20.4 0.046 13.4 8.2 2.8 2 1 1 3 3 3 0 PHD-finger Pam16 PF03656.8 CCK73522.1 - 3.4e-50 169.1 3.5 4e-50 168.8 2.4 1.2 1 0 0 1 1 1 1 Pam16 PMT_C PF11647.3 CCK73522.1 - 0.084 12.5 1.5 0.16 11.5 0.0 2.2 3 0 0 3 3 3 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Zn_clus PF00172.13 CCK73523.1 - 5.6e-06 26.1 9.3 5.6e-06 26.1 6.5 2.2 2 1 1 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 CCK73523.1 - 0.01 15.6 0.0 0.028 14.2 0.0 1.7 1 0 0 1 1 1 0 PAS fold GTP_EFTU PF00009.22 CCK73524.1 - 9.6e-58 194.7 0.0 1.7e-57 193.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CCK73524.1 - 1e-24 86.1 0.1 2.6e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CCK73524.1 - 2.6e-16 59.2 0.1 3.4e-15 55.6 0.1 2.4 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCK73524.1 - 4.8e-08 33.0 0.8 3e-07 30.4 0.6 2.4 1 1 1 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCK73524.1 - 1.5e-05 24.9 0.0 4.1e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 CCK73524.1 - 0.0026 16.8 0.5 0.1 11.6 0.0 3.0 3 0 0 3 3 3 1 AIG1 family PI3_PI4_kinase PF00454.22 CCK73525.1 - 3.3e-57 193.6 0.0 4.8e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase ChAPs PF09295.5 CCK73526.1 - 1.4e-43 149.1 5.1 2.6e-36 125.2 1.2 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 CCK73526.1 - 1.9e-05 24.1 0.0 0.00085 18.9 0.1 2.9 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 CCK73526.1 - 8.7e-05 22.1 0.6 0.025 14.4 0.2 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCK73526.1 - 0.0008 20.0 0.0 0.0017 18.9 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCK73526.1 - 0.0009 19.1 0.1 0.0027 17.6 0.1 1.8 2 0 0 2 2 1 1 Tetratricopeptide repeat Apc3 PF12895.2 CCK73526.1 - 0.001 19.1 0.1 0.004 17.2 0.1 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCK73526.1 - 0.0015 18.1 1.4 0.12 12.1 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCK73526.1 - 0.002 17.6 0.9 0.015 14.9 0.3 2.6 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCK73526.1 - 0.011 15.8 0.0 0.067 13.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCK73526.1 - 0.014 15.6 0.0 0.014 15.6 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Spore_coat_CotO PF14153.1 CCK73526.1 - 0.027 13.8 6.8 0.047 13.1 4.7 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Sialidase_penC PF12135.3 CCK73526.1 - 0.03 13.9 2.7 0.086 12.4 1.9 1.8 1 0 0 1 1 1 0 Sialidase enzyme penultimate C terminal domain DHHW PF14286.1 CCK73526.1 - 0.14 11.4 6.2 0.28 10.4 4.3 1.4 1 0 0 1 1 1 0 DHHW protein SAPS PF04499.10 CCK73527.1 - 1.4e-165 551.5 2.1 1.4e-165 551.5 1.4 2.4 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein Arm PF00514.18 CCK73527.1 - 0.016 15.0 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat PTPLA PF04387.9 CCK73528.1 - 2.1e-50 170.3 10.9 3.1e-50 169.8 7.6 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Ribosomal_L21p PF00829.16 CCK73529.1 - 3.4e-05 23.9 0.1 4.2e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.20 CCK73530.1 - 9.7e-65 218.2 0.0 2e-64 217.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCK73530.1 - 8.8e-44 149.5 0.0 1.6e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCK73530.1 - 2.1e-10 40.0 0.0 8.5e-08 31.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CCK73530.1 - 0.3 10.7 0.1 0.5 10.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Na_H_Exchanger PF00999.16 CCK73531.1 - 3.5e-63 213.4 35.0 5.3e-63 212.8 24.3 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF485 PF04341.7 CCK73531.1 - 0.0029 17.2 0.2 0.0029 17.2 0.2 4.0 4 0 0 4 4 4 1 Protein of unknown function, DUF485 DUF1170 PF06663.8 CCK73531.1 - 0.028 14.3 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1170) Ion_trans_2 PF07885.11 CCK73532.1 - 4.9e-25 87.0 26.1 7.2e-15 54.4 6.6 3.4 4 0 0 4 4 4 2 Ion channel Pox_A14 PF05767.7 CCK73532.1 - 1.4 8.9 8.4 0.47 10.4 0.1 3.3 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF21 PF01595.15 CCK73532.1 - 6.2 6.0 9.7 0.11 11.8 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF21 UvrD_C PF13361.1 CCK73533.1 - 4.7e-71 240.0 0.2 4.7e-71 240.0 0.1 2.8 3 1 0 3 3 3 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CCK73533.1 - 1.8e-63 214.7 0.3 1.8e-63 214.7 0.2 3.7 5 1 0 5 5 5 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 CCK73533.1 - 5e-10 39.4 0.1 8.6e-07 29.0 0.0 3.0 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 CCK73533.1 - 2.8e-09 36.6 0.0 5.8e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCK73533.1 - 0.04 13.4 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain GWT1 PF06423.7 CCK73534.1 - 2.8e-43 147.2 7.2 6.4e-43 146.1 4.0 2.4 2 0 0 2 2 2 1 GWT1 BRCT PF00533.21 CCK73535.1 - 4.9e-17 61.8 8.5 1.3e-05 25.2 0.1 5.2 4 1 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCK73535.1 - 1.1e-11 44.3 0.2 2.6e-05 24.0 0.0 3.7 3 0 0 3 3 3 3 twin BRCT domain Zn_clus PF00172.13 CCK73536.1 - 1.3e-08 34.5 12.3 2.4e-08 33.7 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OTCace PF00185.19 CCK73537.1 - 3.4e-43 147.2 0.5 6.9e-43 146.2 0.2 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 CCK73537.1 - 3.5e-41 140.1 1.2 6.8e-41 139.2 0.1 2.0 3 0 0 3 3 3 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain RNA_lig_T4_1 PF09511.5 CCK73538.1 - 2.1e-78 262.7 0.0 4.9e-78 261.6 0.0 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 CCK73538.1 - 1.2e-70 236.7 0.5 1.2e-70 236.7 0.3 2.5 3 0 0 3 3 3 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 CCK73538.1 - 5.3e-53 179.8 4.2 8.9e-53 179.1 2.9 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain ABC_tran PF00005.22 CCK73538.1 - 0.025 14.8 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 ABC transporter Exo70 PF03081.10 CCK73539.1 - 1.9e-83 280.2 12.1 1.9e-83 280.2 8.4 2.1 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Cytochrom_B562 PF07361.6 CCK73539.1 - 0.13 12.6 4.7 0.92 9.9 0.1 3.6 3 1 1 4 4 4 0 Cytochrome b562 Arrestin_C PF02752.17 CCK73540.1 - 1.6e-13 50.9 0.1 1.6e-13 50.9 0.1 4.1 4 1 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCK73540.1 - 4.1e-08 33.1 1.3 0.00018 21.3 0.2 2.7 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Actin PF00022.14 CCK73541.1 - 2.1e-92 309.5 0.0 1.1e-57 195.3 0.0 2.0 2 0 0 2 2 2 2 Actin MreB_Mbl PF06723.8 CCK73541.1 - 0.0049 15.4 0.1 0.92 8.0 0.0 2.6 2 1 0 2 2 2 2 MreB/Mbl protein KH_1 PF00013.24 CCK73542.1 - 4.7e-80 263.1 29.9 6.8e-13 48.0 0.5 11.6 11 1 0 11 11 11 8 KH domain KH_3 PF13014.1 CCK73542.1 - 9.9e-51 168.6 21.0 1.2e-08 34.4 0.0 10.2 9 0 0 9 9 9 7 KH domain KH_2 PF07650.12 CCK73542.1 - 2.1e-13 49.5 16.2 3e-05 23.5 0.0 7.2 6 0 0 6 6 6 4 KH domain SLS PF14611.1 CCK73542.1 - 2.6e-06 27.0 20.4 0.34 10.3 0.7 6.7 3 1 3 6 6 6 4 Mitochondrial inner-membrane-bound regulator BMC PF00936.14 CCK73542.1 - 0.00072 19.1 0.4 8.4 6.1 0.1 5.5 8 0 0 8 8 8 1 BMC domain KH_5 PF13184.1 CCK73542.1 - 0.0079 15.9 19.7 3.8 7.3 0.0 7.3 8 0 0 8 8 8 2 NusA-like KH domain KH_4 PF13083.1 CCK73542.1 - 0.022 14.3 0.0 0.022 14.3 0.0 6.3 9 0 0 9 9 9 0 KH domain TPK_B1_binding PF04265.9 CCK73542.1 - 0.052 13.2 0.1 14 5.5 0.0 2.8 2 0 0 2 2 2 0 Thiamin pyrophosphokinase, vitamin B1 binding domain Esterase PF00756.15 CCK73543.1 - 1.7e-59 201.2 0.0 2e-59 201.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CCK73543.1 - 0.047 13.4 0.0 0.081 12.6 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family CAP PF00188.21 CCK73544.1 - 6.6e-19 68.6 3.2 1.3e-18 67.6 2.2 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CdCA1 PF10563.4 CCK73544.1 - 0.018 14.5 0.4 0.018 14.5 0.3 2.2 2 0 0 2 2 2 0 Cadmium carbonic anhydrase repeat DUF3484 PF11983.3 CCK73544.1 - 0.045 14.5 2.3 0.17 12.7 1.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) Cytokin_check_N PF10407.4 CCK73545.1 - 4.6e-27 93.4 0.3 1.2e-26 92.1 0.2 1.8 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus SMC_N PF02463.14 CCK73546.1 - 1.2e-51 175.0 61.7 3.1e-51 173.7 42.8 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCK73546.1 - 4.7e-29 100.8 0.0 1.7e-28 98.9 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCK73546.1 - 8.6e-11 42.3 14.1 3.2e-06 27.3 7.7 5.3 3 2 1 4 4 4 2 AAA domain BLOC1_2 PF10046.4 CCK73546.1 - 0.00029 20.9 3.1 0.00029 20.9 2.2 9.7 6 3 2 9 9 9 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_29 PF13555.1 CCK73546.1 - 0.0022 17.4 0.0 0.0055 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DnaJ PF00226.26 CCK73547.1 - 6e-18 64.3 1.9 6e-18 64.3 1.3 3.0 2 0 0 2 2 2 1 DnaJ domain Sld5 PF05916.6 CCK73548.1 - 4e-17 62.4 0.9 8.2e-17 61.4 0.6 1.5 1 0 0 1 1 1 1 GINS complex protein DUF619 PF04768.8 CCK73549.1 - 1.8e-48 164.1 0.0 4.7e-48 162.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF619) A_deaminase PF00962.17 CCK73550.1 - 1.9e-14 53.3 0.0 1.2e-08 34.2 0.0 2.8 2 1 0 2 2 2 2 Adenosine/AMP deaminase SID PF11778.3 CCK73551.1 - 4.2e-39 133.6 5.4 4.2e-39 133.6 3.8 3.9 3 2 1 4 4 4 1 Septation initiation FAD_binding_2 PF00890.19 CCK73551.1 - 0.15 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Reo_sigmaC PF04582.7 CCK73551.1 - 0.4 9.8 5.6 0.26 10.4 1.0 2.4 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF349 PF03993.7 CCK73551.1 - 0.9 9.7 13.6 5.1 7.3 1.9 3.4 2 1 0 2 2 2 0 Domain of Unknown Function (DUF349) PilJ PF13675.1 CCK73551.1 - 4.3 7.6 9.7 2.7 8.3 0.9 3.2 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4239 PF14023.1 CCK73551.1 - 8 5.7 9.0 2.1 7.6 0.5 3.2 2 1 0 3 3 3 0 Protein of unknown function (DUF4239) DUF883 PF05957.8 CCK73551.1 - 8.6 6.8 9.7 1 9.7 0.1 3.7 3 2 2 5 5 5 0 Bacterial protein of unknown function (DUF883) Spc42p PF11544.3 CCK73552.1 - 2e-10 40.4 7.1 2e-10 40.4 4.9 3.2 2 1 0 3 3 3 1 Spindle pole body component Spc42p Retrotrans_gag PF03732.12 CCK73553.1 - 4.8e-08 32.9 0.0 1.2e-07 31.6 0.0 1.8 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC PF00098.18 CCK73553.1 - 0.00011 21.9 0.2 0.00018 21.2 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 CCK73553.1 - 0.00067 19.0 0.2 0.0013 18.2 0.1 1.4 1 0 0 1 1 1 1 Zinc knuckle NapB PF03892.9 CCK73553.1 - 0.023 14.4 0.1 0.049 13.2 0.1 1.6 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) PI-PLC-X PF00388.14 CCK73553.1 - 0.063 12.6 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Lipoxygenase PF00305.14 CCK73553.1 - 0.064 11.2 0.0 0.088 10.7 0.0 1.1 1 0 0 1 1 1 0 Lipoxygenase zf-CCHC_4 PF14392.1 CCK73553.1 - 0.14 11.8 0.3 0.38 10.4 0.2 1.8 1 0 0 1 1 1 0 Zinc knuckle WD40 PF00400.27 CCK73554.1 - 6.6e-17 60.6 0.4 8.6e-06 25.4 0.0 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCK73554.1 - 0.00036 19.9 0.0 0.016 14.6 0.0 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PTPlike_phytase PF14566.1 CCK73556.1 - 0.012 15.6 1.0 0.019 14.9 0.6 1.5 1 1 0 1 1 1 0 Inositol hexakisphosphate Phosphodiest PF01663.17 CCK73557.1 - 5.2e-11 42.4 4.8 8.4e-08 31.9 0.5 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CCK73557.1 - 7.7e-05 22.2 0.1 0.00014 21.3 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 CCK73557.1 - 0.00052 19.3 0.0 0.00093 18.4 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Nup54 PF13874.1 CCK73558.1 - 0.76 9.4 10.3 1.2 8.7 6.2 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Aminotran_1_2 PF00155.16 CCK73559.1 - 4.3e-85 285.8 0.0 5e-85 285.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CCK73559.1 - 7.5e-07 28.5 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CCK73559.1 - 0.00031 19.1 0.0 0.00094 17.5 0.0 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CCK73559.1 - 0.0016 17.2 0.0 0.0061 15.3 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCK73559.1 - 0.017 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_3 PF00202.16 CCK73559.1 - 0.023 13.5 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-III DUF2240 PF09999.4 CCK73559.1 - 0.024 14.0 0.0 0.073 12.5 0.0 1.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) CLN3 PF02487.12 CCK73560.1 - 2.7e-135 451.2 16.8 6.9e-134 446.6 11.7 2.0 1 1 0 1 1 1 1 CLN3 protein HbrB PF08539.6 CCK73561.1 - 3.9e-27 95.0 3.5 7.8e-27 94.0 2.5 1.5 1 0 0 1 1 1 1 HbrB-like Pkinase PF00069.20 CCK73562.1 - 1.9e-35 122.2 0.0 1.6e-34 119.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCK73562.1 - 6.4e-19 68.0 0.0 7.4e-18 64.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase zinc_ribbon_2 PF13240.1 CCK73562.1 - 0.02 14.3 0.3 0.039 13.4 0.2 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Kdo PF06293.9 CCK73562.1 - 0.043 12.8 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCK73562.1 - 0.099 12.3 0.2 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family OrfB_Zn_ribbon PF07282.6 CCK73562.1 - 0.12 12.0 0.1 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 CCK73562.1 - 0.12 11.5 0.1 0.26 10.5 0.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-H2C2_2 PF13465.1 CCK73563.1 - 1.7e-17 62.7 23.7 8.8e-09 35.2 0.2 8.5 11 0 0 11 11 11 4 Zinc-finger double domain zf-C2H2 PF00096.21 CCK73563.1 - 1.3e-14 53.5 85.3 6.1e-06 26.2 0.5 9.3 10 0 0 10 10 10 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCK73563.1 - 2.9e-13 49.1 56.4 0.0033 17.6 4.0 8.6 9 0 0 9 9 9 6 C2H2-type zinc finger zf-met PF12874.2 CCK73563.1 - 0.00017 21.6 37.5 0.2 11.9 1.9 7.4 7 0 0 7 7 7 4 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CCK73563.1 - 0.01 15.6 31.1 0.031 14.1 0.4 6.7 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCK73563.1 - 0.047 13.8 0.4 0.047 13.8 0.3 7.5 7 0 0 7 7 7 0 Zinc-finger double-stranded RNA-binding Lysine_decarbox PF03641.9 CCK73564.1 - 4.5e-44 149.4 0.2 5.7e-44 149.1 0.1 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase Tim54 PF11711.3 CCK73565.1 - 7.6e-131 436.2 0.8 8.7e-131 436.0 0.6 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Vfa1 PF08432.5 CCK73565.1 - 0.44 10.5 10.1 0.043 13.8 0.9 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Vps26 PF03643.10 CCK73566.1 - 2.4e-107 357.8 1.3 2.9e-107 357.5 0.9 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_C PF02752.17 CCK73566.1 - 0.00035 20.6 0.4 0.0059 16.7 0.1 2.5 1 1 1 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCK73566.1 - 0.01 15.6 2.2 0.59 9.9 0.6 3.2 2 1 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain COX3 PF00510.13 CCK73566.1 - 0.068 12.5 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase subunit III rRNA_proc-arch PF13234.1 CCK73568.1 - 4.3e-93 311.3 0.6 4.3e-93 311.3 0.5 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 CCK73568.1 - 1e-62 210.6 0.2 2.9e-62 209.0 0.1 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CCK73568.1 - 9.6e-22 77.2 0.0 1.4e-20 73.4 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCK73568.1 - 2.7e-06 27.1 0.0 6.9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EF1G PF00647.14 CCK73569.1 - 7.6e-48 160.6 0.2 1.9e-47 159.3 0.1 1.7 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CCK73569.1 - 9.8e-13 47.9 1.4 2.7e-12 46.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCK73569.1 - 3.5e-09 36.7 0.1 1.2e-08 34.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCK73569.1 - 0.00016 21.5 0.1 0.00031 20.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCK73569.1 - 0.00046 20.6 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCK73569.1 - 0.0047 16.9 0.1 0.12 12.3 0.0 3.0 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain Snf7 PF03357.16 CCK73570.1 - 9.7e-12 44.5 17.3 9.7e-12 44.5 12.0 2.2 1 1 0 2 2 2 1 Snf7 FlxA PF14282.1 CCK73570.1 - 0.81 9.6 22.3 0.33 10.9 6.5 3.1 2 1 1 3 3 3 0 FlxA-like protein Cullin PF00888.17 CCK73571.1 - 1.1e-15 57.2 10.6 1.1e-15 57.2 7.3 2.4 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.4 CCK73571.1 - 0.017 14.9 0.0 0.054 13.3 0.0 1.8 1 0 0 1 1 1 0 Cullin protein neddylation domain UPF0086 PF01868.11 CCK73572.1 - 3.1e-16 58.7 0.0 5.1e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 BPL_LplA_LipB PF03099.14 CCK73573.1 - 2.8e-21 75.8 0.0 1.9e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Biotin/lipoate A/B protein ligase family DSPn PF14671.1 CCK73574.1 - 3.5e-51 172.9 0.0 6.6e-50 168.7 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CCK73574.1 - 2.7e-24 85.2 0.1 2e-22 79.1 0.0 3.0 3 1 0 3 3 3 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 CCK73574.1 - 0.00016 21.1 0.1 0.00038 19.9 0.1 1.5 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 CCK73574.1 - 0.00046 19.6 0.0 0.0013 18.1 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCK73574.1 - 0.002 18.1 0.0 0.0057 16.7 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate TFIIF_alpha PF05793.7 CCK73574.1 - 0.0098 14.3 14.4 0.017 13.5 10.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Y_phosphatase3 PF13350.1 CCK73574.1 - 0.06 13.5 0.1 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Cwf_Cwc_15 PF04889.7 CCK73574.1 - 0.24 11.0 15.0 0.37 10.4 10.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PBP1_TM PF14812.1 CCK73574.1 - 3.5 8.0 14.5 9.5 6.6 1.7 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ORC6 PF05460.8 CCK73574.1 - 9.1 5.2 9.7 15 4.5 6.7 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ProRS-C_1 PF09180.6 CCK73575.1 - 1.1e-25 89.2 0.4 3.7e-25 87.6 0.4 1.9 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 CCK73575.1 - 5.8e-22 77.4 0.1 1.5e-21 76.1 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 CCK73575.1 - 2.6e-21 75.9 0.0 4.2e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 CCK73576.1 - 7.5e-76 255.0 0.0 1.2e-75 254.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCK73576.1 - 2.8e-11 43.0 0.0 5.8e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA_anti-like PF12869.2 CCK73576.1 - 0.01 15.2 0.4 0.02 14.4 0.3 1.4 1 0 0 1 1 1 0 tRNA_anti-like Ins134_P3_kin PF05770.6 CCK73576.1 - 0.016 14.2 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase Lyase_1 PF00206.15 CCK73577.1 - 1.4e-95 320.0 0.0 1.9e-95 319.6 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 CCK73577.1 - 1.7e-24 85.6 0.0 3.7e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal DUF1776 PF08643.5 CCK73578.1 - 4.7e-34 117.8 0.3 6.2e-34 117.4 0.2 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) DUF500 PF04366.7 CCK73579.1 - 5.8e-44 148.5 0.2 1.2e-43 147.5 0.1 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CCK73579.1 - 1e-15 56.8 0.2 2.2e-15 55.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCK73579.1 - 1.6e-14 53.1 0.1 3e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCK73579.1 - 8.1e-14 50.8 0.1 1.9e-13 49.6 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain RRM_1 PF00076.17 CCK73580.1 - 1.8e-43 146.0 10.0 6.7e-15 54.4 0.1 4.9 4 1 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCK73580.1 - 1.3e-32 111.5 0.4 3.8e-10 39.5 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCK73580.1 - 5.5e-22 77.3 4.4 2.7e-07 30.3 0.7 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCK73580.1 - 7.2e-05 22.5 0.7 0.12 12.2 0.0 3.7 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 CCK73580.1 - 0.00066 19.3 0.0 0.26 11.0 0.0 3.4 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CCK73580.1 - 0.02 14.6 0.0 0.95 9.2 0.0 3.1 3 0 0 3 3 3 0 Limkain b1 Arrestin_C PF02752.17 CCK73581.1 - 1.4e-25 89.9 1.4 2.1e-24 86.1 0.0 3.0 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCK73581.1 - 7.3e-10 38.8 0.0 3.3e-08 33.4 0.0 2.8 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CCK73581.1 - 0.00054 19.5 0.1 0.0019 17.7 0.0 1.9 2 0 0 2 2 2 1 Arrestin_N terminal like WD40 PF00400.27 CCK73582.1 - 9.8e-09 34.7 4.6 0.00012 21.8 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CCK73582.1 - 0.0042 15.9 0.8 0.017 13.9 0.3 2.0 1 1 2 3 3 3 1 Coatomer WD associated region TIP120 PF08623.5 CCK73583.1 - 9.5e-10 38.3 0.3 6.9e-08 32.2 0.0 2.8 2 0 0 2 2 2 2 TATA-binding protein interacting (TIP20) His_kinase PF06580.8 CCK73583.1 - 1.4 8.8 5.8 11 6.0 0.1 3.5 4 0 0 4 4 4 0 Histidine kinase GTP_EFTU PF00009.22 CCK73584.1 - 2.5e-32 111.8 6.9 2.5e-32 111.8 4.8 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CCK73584.1 - 3.3e-21 75.1 0.8 1.3e-20 73.2 0.6 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CCK73584.1 - 1.9e-09 37.4 0.6 0.00028 20.9 0.0 3.0 2 0 0 2 2 2 2 Elongation factor Tu domain 2 IF2_N PF04760.10 CCK73584.1 - 2e-09 36.9 0.0 6.1e-09 35.4 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.18 CCK73584.1 - 8.1e-07 29.0 0.8 2e-06 27.7 0.5 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCK73584.1 - 1.6e-05 25.3 2.1 2.7e-05 24.6 0.2 2.2 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 CCK73584.1 - 0.0005 19.4 1.3 0.0017 17.7 0.2 2.2 2 0 0 2 2 2 1 Ras family Dynamin_N PF00350.18 CCK73584.1 - 0.0015 18.4 1.8 0.7 9.7 0.1 3.1 2 1 1 3 3 3 2 Dynamin family PDCD2_C PF04194.8 CCK73585.1 - 3.9e-41 140.3 2.9 1.5e-39 135.2 0.0 3.0 2 1 1 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain AA_permease PF00324.16 CCK73586.1 - 5.2e-123 410.8 41.3 6.1e-123 410.6 28.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCK73586.1 - 2.2e-33 115.4 42.8 2.8e-33 115.1 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease zf-CCHC PF00098.18 CCK73587.1 - 6.4e-06 25.8 2.4 1.2e-05 25.0 1.6 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CCK73587.1 - 0.0015 18.1 1.1 0.004 16.7 0.8 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 CCK73587.1 - 0.11 12.2 1.8 0.17 11.6 1.2 1.3 1 0 0 1 1 1 0 Zinc knuckle ASF1_hist_chap PF04729.8 CCK73588.1 - 1.9e-67 225.7 0.1 2.5e-67 225.3 0.1 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Nop14 PF04147.7 CCK73588.1 - 0.67 7.8 44.5 0.82 7.5 30.8 1.1 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 CCK73588.1 - 1.3 8.2 25.1 2 7.5 17.4 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T BUD22 PF09073.5 CCK73588.1 - 6.3 5.7 35.7 7.8 5.4 24.7 1.2 1 0 0 1 1 1 0 BUD22 SUN PF03856.8 CCK73589.1 - 7.6e-102 339.8 13.9 1e-101 339.4 9.6 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) IL2 PF00715.12 CCK73589.1 - 0.083 12.6 0.1 3.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Interleukin 2 zf-MYND PF01753.13 CCK73589.1 - 0.44 10.4 3.7 0.98 9.3 2.6 1.5 1 0 0 1 1 1 0 MYND finger Pho86 PF11124.3 CCK73590.1 - 4.8e-89 298.3 5.9 5.4e-89 298.1 4.1 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 Methyltransf_4 PF02390.12 CCK73590.1 - 0.0066 15.5 0.1 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PTS_EIIC PF02378.13 CCK73590.1 - 0.045 12.5 0.0 0.061 12.1 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC MarC PF01914.12 CCK73590.1 - 0.07 12.2 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 MarC family integral membrane protein Ribul_P_3_epim PF00834.14 CCK73591.1 - 6.7e-73 244.0 0.0 7.9e-73 243.8 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 CCK73591.1 - 0.0026 17.1 0.1 0.0054 16.1 0.0 1.5 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.12 CCK73591.1 - 0.0074 15.5 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 PcrB family QRPTase_C PF01729.14 CCK73591.1 - 0.016 14.7 0.0 0.14 11.6 0.0 2.2 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain ThiG PF05690.9 CCK73591.1 - 0.089 11.8 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Alb1 PF09135.6 CCK73592.1 - 2.2e-14 53.9 12.4 2.2e-14 53.9 8.6 2.0 1 1 1 2 2 2 1 Alb1 DUF2413 PF10310.4 CCK73593.1 - 3.8e-108 362.1 28.2 4.6e-108 361.8 19.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) GCD14 PF08704.5 CCK73594.1 - 1.7e-78 263.5 0.1 1.1e-77 260.8 0.0 2.1 2 1 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 CCK73594.1 - 7.1e-05 23.3 0.0 0.00016 22.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCK73594.1 - 0.00028 20.9 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 CCK73594.1 - 0.00032 19.8 0.0 0.0007 18.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Gcd10p PF04189.8 CCK73594.1 - 0.00049 19.3 0.7 0.0047 16.1 0.0 2.2 2 0 0 2 2 2 1 Gcd10p family DUF3748 PF12566.3 CCK73594.1 - 0.00051 19.9 0.0 0.0009 19.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3748) Methyltransf_31 PF13847.1 CCK73594.1 - 0.002 17.7 0.0 0.0051 16.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCK73594.1 - 0.056 13.1 0.0 0.14 11.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain CN_hydrolase PF00795.17 CCK73595.1 - 3.5e-26 91.7 0.0 4.5e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zf-H2C2 PF09337.5 CCK73596.1 - 2.8e-21 74.6 6.7 8.6e-21 73.0 4.6 1.9 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 CCK73596.1 - 0.00011 22.1 0.0 0.00026 20.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 CCK73596.1 - 0.05 13.5 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Pkinase PF00069.20 CCK73598.1 - 1e-56 191.9 0.1 1.3e-55 188.4 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCK73598.1 - 1.6e-36 125.6 0.0 2.9e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCK73598.1 - 3.4e-06 26.2 0.0 9.1e-06 24.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like TrkH PF02386.11 CCK73599.1 - 1.6e-139 464.4 6.8 1.8e-138 460.9 0.6 2.1 2 0 0 2 2 2 2 Cation transport protein NOA36 PF06524.7 CCK73599.1 - 0.51 9.5 13.3 0.35 10.0 3.7 2.5 2 0 0 2 2 2 0 NOA36 protein TRAP_alpha PF03896.11 CCK73599.1 - 3.9 6.4 9.6 0.13 11.2 1.9 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 CCK73599.1 - 5.7 6.4 16.9 0.12 11.9 2.2 3.3 3 0 0 3 3 3 0 Sigma-70, non-essential region CPSase_L_D2 PF02786.12 CCK73600.1 - 2e-114 380.1 1.6 1e-83 279.8 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CCK73600.1 - 4.2e-47 158.9 0.0 1.4e-46 157.2 0.0 1.9 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CCK73600.1 - 8.9e-44 149.2 0.0 2.1e-43 148.0 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 CCK73600.1 - 1e-40 138.6 0.0 2.2e-40 137.6 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 CCK73600.1 - 1.6e-39 134.4 0.1 1.2e-38 131.6 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 CCK73600.1 - 1.8e-39 134.2 0.0 1.4e-18 67.0 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace PF00185.19 CCK73600.1 - 9.2e-36 123.0 0.2 1.7e-34 119.0 0.1 2.7 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 CCK73600.1 - 5e-32 111.1 0.6 7.1e-21 74.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCK73600.1 - 2.4e-22 79.1 0.3 9.1e-13 47.6 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 CCK73600.1 - 2.3e-20 72.3 0.0 1e-19 70.2 0.0 2.3 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 CCK73600.1 - 2.2e-16 59.8 2.9 2.4e-09 36.8 0.3 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CCK73600.1 - 1.3e-14 53.9 0.7 3.7e-07 29.6 0.1 2.4 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 CCK73600.1 - 4.6e-07 29.4 0.4 1.2e-05 24.8 0.3 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Peptidase_C26 PF07722.8 CCK73600.1 - 7.5e-07 28.8 0.0 2e-05 24.1 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 CCK73600.1 - 1.3e-06 28.3 1.0 0.01 15.6 0.2 2.7 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 CCK73600.1 - 0.052 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 DJ-1/PfpI family mIF3 PF14877.1 CCK73601.1 - 1.7e-59 200.2 7.6 1.7e-59 200.2 5.3 1.9 2 0 0 2 2 2 1 Mitochondrial translation initiation factor DUF655 PF04919.7 CCK73601.1 - 0.0021 17.7 0.4 0.0021 17.7 0.3 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF655) Zn_dep_PLPC PF00882.13 CCK73602.1 - 9.4e-17 61.1 0.5 1.7e-16 60.2 0.4 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C FG-GAP PF01839.18 CCK73602.1 - 0.09 12.5 1.4 0.19 11.4 0.1 2.3 2 0 0 2 2 2 0 FG-GAP repeat Mito_carr PF00153.22 CCK73603.1 - 1.8e-64 213.4 2.9 2.1e-21 75.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AhpC-TSA_2 PF13911.1 CCK73603.1 - 0.0047 16.8 0.0 0.0075 16.1 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme INT_SG_DDX_CT_C PF15300.1 CCK73604.1 - 0.024 14.0 0.0 0.055 12.9 0.0 1.5 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus DUF2638 PF10937.3 CCK73604.1 - 0.051 14.5 0.0 0.055 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2638) PAP2 PF01569.16 CCK73605.1 - 3.6e-15 55.7 2.4 1.1e-14 54.2 1.7 1.7 1 0 0 1 1 1 1 PAP2 superfamily Fer4_5 PF12801.2 CCK73605.1 - 0.019 14.7 1.7 0.019 14.7 1.2 2.9 3 0 0 3 3 3 0 4Fe-4S binding domain Ribosomal_S21e PF01249.13 CCK73606.1 - 4.9e-39 132.1 0.0 5.4e-39 132.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Pkinase PF00069.20 CCK73607.1 - 1.5e-51 175.0 0.0 6e-51 173.0 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCK73607.1 - 3.8e-21 75.3 0.0 7.6e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCK73607.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Tim17 PF02466.14 CCK73608.1 - 1.9e-33 115.1 3.6 2.3e-33 114.9 2.5 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CRAL_TRIO PF00650.15 CCK73609.1 - 6.3e-28 97.2 0.2 6.3e-28 97.2 0.2 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCK73609.1 - 4.6e-06 26.6 0.3 2.2e-05 24.4 0.2 2.3 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain Fra10Ac1 PF09725.4 CCK73609.1 - 0.35 10.9 4.4 0.38 10.8 0.3 2.6 2 1 0 2 2 2 0 Folate-sensitive fragile site protein Fra10Ac1 F-box-like PF12937.2 CCK73610.1 - 1.7e-08 34.0 0.1 4.6e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCK73610.1 - 0.00023 20.7 0.0 0.00069 19.2 0.0 1.8 1 0 0 1 1 1 1 F-box domain FMN_red PF03358.10 CCK73611.1 - 1.2e-31 109.2 0.0 1.6e-31 108.8 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 CCK73611.1 - 2.6e-06 27.0 0.0 3.1e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Mut7-C PF01927.11 CCK73613.1 - 0.9 9.4 3.4 5.4 6.9 0.0 2.7 3 0 0 3 3 3 0 Mut7-C RNAse domain Sugar_tr PF00083.19 CCK73614.1 - 2.3e-167 557.1 34.3 2.6e-167 556.9 23.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCK73614.1 - 2.1e-30 105.6 43.1 1.9e-24 86.0 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily