# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Sir1 PF11603.8 CCC66571.1 - 1.6e-37 128.6 0.1 1.4e-36 125.6 0.1 2.2 2 0 0 2 2 2 1 Regulatory protein Sir1 GST_C PF00043.25 CCC66574.1 - 1e-10 41.7 0.0 1.9e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCC66574.1 - 7.1e-06 26.0 0.1 2e-05 24.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCC66574.1 - 3.9e-05 23.8 0.4 7.4e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CCC66574.1 - 0.0077 16.6 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CCC66574.1 - 0.063 13.7 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GLEYA PF10528.9 CCC66575.1 - 2.1e-56 188.3 29.8 1.8e-19 70.0 2.3 5.1 5 0 0 5 5 5 3 GLEYA domain PA14 PF07691.12 CCC66575.1 - 6.6e-35 120.1 3.4 1.6e-12 47.4 0.1 4.0 3 0 0 3 3 3 3 PA14 domain Flocculin PF00624.18 CCC66575.1 - 1.6e-09 37.9 77.9 4.6e-06 26.8 21.3 13.7 15 2 1 16 16 16 3 Flocculin repeat DUF5060 PF16586.5 CCC66575.1 - 0.19 12.1 6.0 38 4.7 0.1 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5060) Sec10 PF07393.11 CCC66576.1 - 4.1e-62 210.6 25.7 5.3e-62 210.3 25.7 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 RNA_pol_Rpb1_5 PF04998.17 CCC66576.1 - 0.029 13.8 1.4 0.056 12.9 1.4 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Endonuclease_NS PF01223.23 CCC66578.1 - 3.2e-65 220.1 0.0 3.9e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease UCR_14kD PF02271.16 CCC66581.1 - 1.6e-37 127.5 0.1 1.8e-37 127.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit ATP_transf PF09830.9 CCC66582.1 - 2e-18 66.3 0.0 3.6e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 CCC66582.1 - 5.3e-05 22.6 0.0 9.9e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) DUF4922 PF16269.5 CCC66582.1 - 0.0033 17.2 0.2 0.0057 16.4 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) HIT PF01230.23 CCC66582.1 - 0.012 16.3 0.0 0.034 14.9 0.0 1.7 1 0 0 1 1 1 0 HIT domain Fumble PF03630.14 CCC66583.1 - 8e-124 413.1 8.9 1.7e-122 408.7 8.9 2.0 1 1 0 1 1 1 1 Fumble Kre28 PF17097.5 CCC66584.1 - 2.3e-69 234.1 39.4 2.7e-69 233.9 39.4 1.0 1 0 0 1 1 1 1 Spindle pole body component DUF2937 PF11157.8 CCC66584.1 - 0.019 14.7 2.7 2.5 7.8 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) DUF4407 PF14362.6 CCC66584.1 - 0.32 10.3 15.4 0.035 13.4 6.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Adenylsucc_synt PF00709.21 CCC66584.1 - 0.33 9.8 2.4 0.35 9.7 0.1 2.0 2 0 0 2 2 2 0 Adenylosuccinate synthetase Imm7 PF15585.6 CCC66584.1 - 0.53 10.6 6.8 9.4 6.5 0.2 3.4 3 0 0 3 3 3 0 Immunity protein 7 zf-C4H2 PF10146.9 CCC66584.1 - 0.59 10.4 22.7 0.57 10.5 10.5 2.8 1 1 0 2 2 2 0 Zinc finger-containing protein Spore_III_AB PF09548.10 CCC66584.1 - 2 8.5 11.7 2.6 8.1 3.8 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) RPAP1_C PF08620.10 CCC66585.1 - 8.9e-30 102.6 0.1 2e-29 101.5 0.1 1.6 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 CCC66585.1 - 7.1e-15 54.5 7.3 7.1e-15 54.5 7.3 2.8 3 0 0 3 3 3 1 RPAP1-like, N-terminal HEAT PF02985.22 CCC66585.1 - 0.043 14.1 0.0 0.16 12.3 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat SR-25 PF10500.9 CCC66585.1 - 0.098 12.3 11.4 0.17 11.5 11.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pmp3 PF01679.17 CCC66586.1 - 3e-20 72.1 7.0 3.5e-20 71.9 7.0 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator MaAIMP_sms PF16951.5 CCC66586.1 - 0.088 12.6 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative methionine and alanine importer, small subunit SSP160 PF06933.11 CCC66587.1 - 0.068 11.4 13.4 0.08 11.1 13.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ApoL PF05461.11 CCC66587.1 - 0.33 10.2 2.9 0.36 10.1 2.9 1.0 1 0 0 1 1 1 0 Apolipoprotein L Pkinase PF00069.25 CCC66588.1 - 8.2e-64 215.5 0.0 1.2e-63 215.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC66588.1 - 8.4e-47 159.6 0.0 1.2e-46 159.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC66588.1 - 1.2e-08 34.6 0.0 1.3e-05 24.7 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CCC66588.1 - 0.0006 18.7 0.0 0.0012 17.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Recep_L_domain PF01030.24 CCC66589.1 - 5.5e-08 32.9 10.9 0.0011 19.0 0.1 4.5 1 1 2 4 4 4 3 Receptor L domain Bacteriocin_IIc PF10439.9 CCC66589.1 - 0.091 12.9 0.7 50 4.1 0.2 3.4 2 1 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Zn_clus PF00172.18 CCC66590.1 - 9.1e-06 25.7 5.8 1.7e-05 24.8 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ApoA-II PF04711.13 CCC66590.1 - 0.07 13.3 0.1 0.24 11.6 0.1 1.9 1 0 0 1 1 1 0 Apolipoprotein A-II (ApoA-II) FKBP_C PF00254.28 CCC66591.1 - 4.2e-34 116.8 0.0 5.8e-34 116.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CA_like PF10563.9 CCC66591.1 - 0.2 11.5 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Putative carbonic anhydrase Thioredoxin PF00085.20 CCC66592.1 - 1.6e-40 137.3 0.6 1.4e-18 66.8 0.0 3.7 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 CCC66592.1 - 6.5e-13 49.0 10.8 7.9e-11 42.2 4.7 3.7 2 1 2 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CCC66592.1 - 9.4e-05 21.9 0.2 0.028 13.8 0.0 3.3 3 1 1 4 4 4 1 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CCC66592.1 - 0.021 15.0 0.1 1 9.6 0.0 2.9 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_8 PF13905.6 CCC66592.1 - 0.15 12.4 3.5 9.6 6.6 0.0 4.4 4 1 0 4 4 4 0 Thioredoxin-like GRASP55_65 PF04495.14 CCC66593.1 - 3.9e-35 121.2 0.0 3.5e-34 118.1 0.0 2.1 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain Hexokinase_2 PF03727.16 CCC66594.1 - 3.4e-70 236.2 0.0 4.5e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCC66594.1 - 6.1e-68 228.6 0.0 1.1e-67 227.8 0.0 1.4 1 0 0 1 1 1 1 Hexokinase RNase_T PF00929.24 CCC66595.1 - 0.0035 17.9 0.0 0.0098 16.5 0.0 1.8 1 0 0 1 1 1 1 Exonuclease Glutaredoxin PF00462.24 CCC66596.1 - 8.5e-13 48.3 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Chordopox_G3 PF06129.12 CCC66596.1 - 0.0063 17.2 1.3 0.0076 16.9 0.6 1.5 2 0 0 2 2 2 1 Chordopoxvirus G3 protein Thioredoxin_9 PF14595.6 CCC66596.1 - 0.058 13.2 0.1 0.1 12.3 0.1 1.5 1 1 0 1 1 1 0 Thioredoxin DUF1682 PF07946.14 CCC66596.1 - 0.079 12.2 0.2 0.16 11.2 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1682) Thioredoxin_7 PF13899.6 CCC66596.1 - 0.098 12.8 0.1 0.37 11.0 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin-like DUF3128 PF11326.8 CCC66597.1 - 2.1e-26 92.1 2.2 2.4e-26 91.9 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Complex1_LYR_2 PF13233.6 CCC66598.1 - 9.6e-19 67.9 0.2 1.6e-18 67.2 0.2 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 CCC66598.1 - 3.7e-11 42.9 0.0 1.3e-10 41.1 0.0 1.9 3 0 0 3 3 3 1 Complex 1 protein (LYR family) DUF4028 PF13220.6 CCC66598.1 - 0.038 13.8 0.2 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) THP2 PF09432.10 CCC66601.1 - 0.0033 17.5 1.7 0.0061 16.6 1.7 1.4 1 0 0 1 1 1 1 Tho complex subunit THP2 PspA_IM30 PF04012.12 CCC66601.1 - 0.0084 15.7 0.8 0.013 15.1 0.8 1.2 1 0 0 1 1 1 1 PspA/IM30 family Tektin PF03148.14 CCC66601.1 - 0.072 11.8 2.3 0.12 11.1 2.3 1.3 1 1 0 1 1 1 0 Tektin family TMF_TATA_bd PF12325.8 CCC66601.1 - 0.083 13.1 7.1 0.33 11.2 7.1 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Taxilin PF09728.9 CCC66601.1 - 0.12 11.5 7.5 0.17 11.0 7.5 1.1 1 0 0 1 1 1 0 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 CCC66601.1 - 0.15 12.1 4.9 0.21 11.6 4.9 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nsp1_C PF05064.13 CCC66601.1 - 0.26 11.1 3.8 0.19 11.6 0.9 2.0 1 1 1 2 2 2 0 Nsp1-like C-terminal region BLOC1_2 PF10046.9 CCC66601.1 - 0.27 11.6 5.8 0.38 11.1 1.8 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 zf-C4H2 PF10146.9 CCC66601.1 - 0.74 10.1 2.8 1.1 9.5 2.8 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein GAS PF13851.6 CCC66601.1 - 0.85 8.9 6.8 1.7 8.0 1.8 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding AA_permease PF00324.21 CCC66602.1 - 2.3e-123 412.3 37.6 2.7e-123 412.1 37.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC66602.1 - 1.7e-30 106.2 35.2 2.1e-30 105.9 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease Colicin_im PF03857.13 CCC66602.1 - 1.1 9.3 5.2 0.27 11.2 1.2 2.1 2 0 0 2 2 2 0 Colicin immunity protein EVI2A PF05399.11 CCC66602.1 - 8.1 6.0 7.9 14 5.2 7.9 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) PSP1 PF04468.12 CCC66603.1 - 1.2e-40 137.6 2.7 2.8e-40 136.5 2.7 1.7 1 0 0 1 1 1 1 PSP1 C-terminal conserved region CAC1F_C PF16885.5 CCC66603.1 - 1.2 8.7 5.9 2.3 7.8 5.9 1.4 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term PAP2 PF01569.21 CCC66604.1 - 4.5e-24 84.8 1.7 4.5e-24 84.8 1.7 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.6 CCC66604.1 - 0.00093 19.7 7.4 0.00093 19.7 7.4 2.9 4 0 0 4 4 4 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 CCC66604.1 - 0.0069 16.1 1.5 0.0069 16.1 1.5 1.8 2 1 0 2 2 2 1 PAP2 superfamily FUSC_2 PF13515.6 CCC66604.1 - 0.088 12.9 6.3 0.037 14.2 2.7 2.2 2 0 0 2 2 2 0 Fusaric acid resistance protein-like S-AdoMet_synt_C PF02773.16 CCC66605.1 - 6.7e-65 217.3 0.0 1.3e-64 216.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 CCC66605.1 - 1.8e-45 153.7 0.3 5.7e-45 152.0 0.1 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 CCC66605.1 - 3.2e-45 153.2 0.0 7e-45 152.2 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 CCC66605.1 - 0.033 13.0 0.3 0.12 11.1 0.1 1.9 1 1 1 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) FHA PF00498.26 CCC66606.1 - 0.0046 17.3 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain Ribosomal_L37e PF01907.19 CCC66607.1 - 1.6e-27 95.4 10.8 2.8e-27 94.6 10.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 CCC66607.1 - 0.002 18.1 1.4 0.0027 17.7 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 CCC66607.1 - 0.01 15.9 0.7 0.012 15.7 0.7 1.3 1 0 0 1 1 1 0 SelR domain zf-RING_5 PF14634.6 CCC66607.1 - 0.033 14.2 3.3 0.05 13.6 3.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain GATA PF00320.27 CCC66607.1 - 0.079 12.6 5.6 0.76 9.4 1.1 2.5 1 1 1 2 2 2 0 GATA zinc finger DUF1258 PF06869.12 CCC66607.1 - 0.29 10.6 4.5 0.18 11.3 3.1 1.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) zinc_ribbon_2 PF13240.6 CCC66607.1 - 0.69 9.7 5.5 9.4 6.1 1.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain LCD1 PF09798.9 CCC66608.1 - 5.3e-205 682.5 24.7 6.4e-205 682.3 24.7 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein TMF_TATA_bd PF12325.8 CCC66608.1 - 0.0072 16.5 5.3 0.022 15.0 5.3 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Ribosomal_L28 PF00830.19 CCC66608.1 - 0.012 15.8 0.2 0.026 14.7 0.2 1.5 1 0 0 1 1 1 0 Ribosomal L28 family Spc7 PF08317.11 CCC66608.1 - 0.084 11.7 8.1 0.19 10.6 8.1 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Nefa_Nip30_N PF10187.9 CCC66608.1 - 0.088 13.2 6.7 0.93 9.9 6.3 2.4 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 FapA PF03961.13 CCC66608.1 - 0.38 9.3 6.9 0.75 8.3 6.9 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A TPR_1 PF00515.28 CCC66609.1 - 5.9e-27 92.4 22.6 6.8e-07 28.9 0.4 10.1 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 CCC66609.1 - 3.2e-25 86.2 18.8 1.8e-05 24.5 0.2 9.3 9 1 0 9 9 9 5 Tetratricopeptide repeat STI1 PF17830.1 CCC66609.1 - 9.5e-17 60.7 12.0 2.3e-11 43.4 4.6 3.0 2 0 0 2 2 2 2 STI1 domain TPR_8 PF13181.6 CCC66609.1 - 2.2e-09 36.8 18.6 0.00082 19.4 0.2 8.6 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCC66609.1 - 5.6e-08 32.3 14.2 0.048 13.3 1.9 7.3 7 3 2 9 9 9 3 TPR repeat TPR_12 PF13424.6 CCC66609.1 - 3.8e-07 30.3 14.5 0.0049 17.1 1.7 6.4 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 CCC66609.1 - 9.9e-06 25.6 7.5 0.48 10.9 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCC66609.1 - 1.1e-05 25.8 5.9 0.74 10.4 2.4 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCC66609.1 - 3.3e-05 24.3 0.1 0.6 11.1 0.0 4.5 4 1 1 5 5 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CCC66609.1 - 0.00043 20.0 11.7 0.51 10.3 0.1 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCC66609.1 - 0.00052 19.8 9.8 7.1 6.9 0.1 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCC66609.1 - 0.0087 16.2 0.0 5.8 7.1 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCC66609.1 - 0.011 16.4 2.2 6.5 7.5 0.4 4.2 6 0 0 6 6 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC66609.1 - 0.12 12.6 8.1 6.1 7.1 0.4 4.5 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 CCC66609.1 - 0.51 11.1 3.0 2.8e+02 2.5 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCC66609.1 - 2.3 8.3 4.9 8.2 6.6 0.0 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF1764 PF08576.10 CCC66609.1 - 8 7.4 18.3 1.6 9.7 7.0 2.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) EMG1 PF03587.14 CCC66610.1 - 1.1e-77 260.1 0.0 1.3e-77 259.8 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase phiKZ_IP PF12699.7 CCC66611.1 - 0.00016 20.9 0.4 0.00033 19.9 0.1 1.6 2 0 0 2 2 2 1 phiKZ-like phage internal head proteins DUF4492 PF14899.6 CCC66611.1 - 0.031 14.2 0.2 0.031 14.2 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4492) Peptidase_C28 PF05408.11 CCC66611.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Foot-and-mouth virus L-proteinase TMEM51 PF15345.6 CCC66611.1 - 0.11 12.4 0.1 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 Baculo_11_kDa PF06143.11 CCC66611.1 - 0.24 11.0 3.3 1.8 8.2 0.0 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family DUF4400 PF14348.6 CCC66611.1 - 8.5 5.8 7.7 0.26 10.8 0.2 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4400) PH PF00169.29 CCC66612.1 - 5.3e-08 33.3 0.2 2.4e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 CCC66612.1 - 0.014 15.8 0.2 0.063 13.7 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Abhydrolase_1 PF00561.20 CCC66614.1 - 1.8e-69 234.3 0.0 2.2e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCC66614.1 - 7.4e-05 23.4 0.1 0.00013 22.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCC66614.1 - 0.017 14.4 0.0 0.28 10.4 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 CCC66614.1 - 0.12 12.5 0.0 0.44 10.7 0.0 1.8 2 0 0 2 2 2 0 TAP-like protein HCO3_cotransp PF00955.21 CCC66615.1 - 2.1e-80 271.0 11.6 3.2e-40 138.4 1.9 2.1 1 1 1 2 2 2 2 HCO3- transporter family MASE2 PF05230.11 CCC66615.1 - 0.063 13.4 0.2 15 5.7 0.0 3.0 3 0 0 3 3 3 0 MASE2 domain 2-Hacid_dh_C PF02826.19 CCC66616.1 - 1.4e-54 184.2 0.0 2.6e-54 183.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCC66616.1 - 4.3e-16 58.8 0.0 5.8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CCC66616.1 - 6e-06 26.5 0.0 2.1e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CCC66616.1 - 4.9e-05 23.0 0.0 0.00023 20.8 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AlaDh_PNT_C PF01262.21 CCC66616.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.21 CCC66616.1 - 0.15 11.4 0.2 2.7 7.3 0.2 2.2 2 0 0 2 2 2 0 ThiF family TIMELESS PF04821.14 CCC66617.1 - 6.4e-87 291.3 6.6 6.4e-87 291.3 6.6 2.9 5 0 0 5 5 5 1 Timeless protein Sec2p PF06428.11 CCC66618.1 - 3.5e-26 91.0 15.9 3.5e-26 91.0 15.9 4.3 4 1 1 5 5 5 2 GDP/GTP exchange factor Sec2p TMCCDC2 PF15844.5 CCC66618.1 - 6 6.8 8.0 0.74 9.7 0.4 2.8 3 0 0 3 3 3 0 Transmembrane and coiled-coil domain-containing protein 2 FH2 PF02181.23 CCC66619.1 - 2.4e-92 310.0 10.8 2.4e-92 310.0 10.8 4.4 3 1 1 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 CCC66619.1 - 2.7e-45 154.4 4.6 2.7e-45 154.4 4.6 3.7 4 0 0 4 4 4 2 Diaphanous FH3 Domain Drf_GBD PF06371.13 CCC66619.1 - 1.6e-25 89.8 5.5 5.5e-20 71.7 0.0 5.5 5 0 0 5 5 5 2 Diaphanous GTPase-binding Domain AA_permease PF00324.21 CCC66620.1 - 1.4e-138 462.5 54.7 1.5e-138 462.4 54.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC66620.1 - 1.9e-29 102.7 63.7 4.1e-29 101.7 63.5 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCC66621.1 - 4.5e-135 450.9 48.0 5.2e-135 450.7 48.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC66621.1 - 7.6e-31 107.4 59.0 1.6e-30 106.3 58.7 1.6 1 1 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.8 CCC66621.1 - 0.16 11.6 2.5 8.7 6.0 0.6 3.2 2 0 0 2 2 2 0 Intrinsic membrane protein PufX PI3_PI4_kinase PF00454.27 CCC66622.1 - 4.7e-34 118.3 2.6 4.7e-34 118.3 0.1 2.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.8 CCC66622.1 - 1.7e-20 72.7 2.9 2.9e-20 72.0 0.3 2.6 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.20 CCC66622.1 - 8.6e-07 28.5 1.4 2.4e-06 27.1 1.4 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 CCC66622.1 - 0.043 13.1 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Ist1 PF03398.14 CCC66623.1 - 2.2e-58 196.8 2.0 2.2e-58 196.8 2.0 1.6 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway XAP5 PF04921.14 CCC66623.1 - 0.36 10.6 8.1 0.68 9.7 8.1 1.4 1 0 0 1 1 1 0 XAP5, circadian clock regulator CDC45 PF02724.14 CCC66623.1 - 2.3 6.4 9.1 3.5 5.8 9.1 1.2 1 0 0 1 1 1 0 CDC45-like protein CRAL_TRIO PF00650.20 CCC66624.1 - 6.4e-40 136.5 0.0 1e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCC66624.1 - 1e-15 57.6 0.1 2.1e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CCC66624.1 - 0.00065 19.9 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain YIF1 PF03878.15 CCC66625.1 - 1.6e-75 253.7 2.3 2e-75 253.4 2.3 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 CCC66625.1 - 0.0081 15.9 8.6 0.015 15.0 8.6 1.5 1 1 0 1 1 1 1 Yip1 domain DUF1744 PF08490.12 CCC66626.1 - 1e-139 465.6 5.4 1.5e-139 465.0 5.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 CCC66626.1 - 6.7e-80 268.8 8.8 1e-79 268.1 6.4 2.6 2 1 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 CCC66626.1 - 1.2e-15 57.2 2.5 2e-12 46.6 0.1 3.9 3 1 0 3 3 3 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 CCC66626.1 - 4.2e-08 33.1 0.7 3.7e-07 30.0 0.7 2.3 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CCC66626.1 - 1.5e-05 25.0 0.4 0.00014 21.9 0.0 2.9 2 0 0 2 2 2 1 RNase_H superfamily zf-H2C2_2 PF13465.6 CCC66626.1 - 1.4 9.5 4.7 14 6.3 0.8 3.2 2 0 0 2 2 2 0 Zinc-finger double domain Yae1_N PF09811.9 CCC66627.1 - 5.8e-10 38.7 0.6 5.8e-10 38.7 0.6 1.7 2 0 0 2 2 2 1 Essential protein Yae1, N terminal SepF PF04472.12 CCC66627.1 - 0.069 13.4 0.4 0.16 12.3 0.4 1.7 1 1 0 1 1 1 0 Cell division protein SepF HMA PF00403.26 CCC66628.1 - 6.4e-11 42.5 0.1 7.6e-11 42.3 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Dsl1_N PF11988.8 CCC66629.1 - 3.2e-132 440.8 28.7 3.2e-132 440.8 28.7 1.8 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 N terminal Dsl1_C PF11989.8 CCC66629.1 - 2.3e-74 249.4 10.3 2.3e-74 249.4 10.3 2.5 2 1 1 3 3 3 1 Retrograde transport protein Dsl1 C terminal VASt PF16016.5 CCC66630.1 - 2.2e-15 57.4 1.6 5.6e-15 56.1 0.8 2.1 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain PH PF00169.29 CCC66630.1 - 8.4e-13 48.8 0.9 1.1e-11 45.1 0.1 2.8 2 0 0 2 2 2 1 PH domain BAR_3 PF16746.5 CCC66630.1 - 1.1e-08 35.0 2.4 1.1e-08 35.0 2.4 2.4 2 0 0 2 2 2 1 BAR domain of APPL family RecO_N_2 PF13114.6 CCC66630.1 - 0.055 13.2 0.2 0.36 10.6 0.1 2.4 2 0 0 2 2 2 0 RecO N terminal Pterin_bind PF00809.22 CCC66631.1 - 3.8e-52 177.4 0.0 3.3e-51 174.3 0.0 2.4 1 1 0 1 1 1 1 Pterin binding enzyme FolB PF02152.18 CCC66631.1 - 1.8e-35 121.8 0.2 1.1e-16 61.3 0.1 2.4 2 0 0 2 2 2 2 Dihydroneopterin aldolase HPPK PF01288.20 CCC66631.1 - 3.8e-34 117.5 0.0 9.7e-34 116.3 0.0 1.7 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) zf-CCHC PF00098.23 CCC66632.1 - 3.2e-56 185.0 58.0 3.9e-09 36.2 2.2 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.6 CCC66632.1 - 2e-15 56.2 41.0 0.014 15.1 0.6 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_5 PF14787.6 CCC66632.1 - 8.7e-08 31.7 36.7 0.33 10.7 0.1 7.1 5 2 2 7 7 7 5 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 CCC66632.1 - 4.2e-07 29.8 45.2 0.5 10.4 0.7 7.0 2 2 5 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.6 CCC66632.1 - 0.00041 20.1 53.1 0.59 10.0 1.6 7.5 7 0 0 7 7 7 5 Zinc knuckle zf-CCHC_6 PF15288.6 CCC66632.1 - 0.014 15.2 2.6 0.014 15.2 2.6 7.0 6 1 1 7 7 7 0 Zinc knuckle AbLIM_anchor PF16182.5 CCC66632.1 - 0.02 14.8 0.2 0.023 14.5 0.2 1.0 1 0 0 1 1 1 0 Putative adherens-junction anchoring region of AbLIM zf-C2H2_10 PF16588.5 CCC66632.1 - 0.12 12.2 40.9 0.48 10.2 0.4 6.5 6 0 0 6 6 6 0 C2H2 zinc-finger TRAF6_Z2 PF18048.1 CCC66632.1 - 1.4 9.1 24.3 3.2 7.9 0.4 5.9 6 1 0 6 6 6 0 TNF receptor-associated factor 6 zinc finger 2 RTC4 PF14474.6 CCC66633.1 - 6e-32 110.4 0.0 1.4e-31 109.1 0.0 1.7 1 0 0 1 1 1 1 RTC4-like domain DHHW PF14286.6 CCC66633.1 - 0.091 12.1 0.1 0.16 11.2 0.1 1.3 1 1 0 1 1 1 0 DHHW protein WD40 PF00400.32 CCC66634.1 - 2.6e-13 50.2 5.6 0.017 16.0 0.1 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC66634.1 - 1.7e-10 41.0 0.0 0.02 15.2 0.0 5.4 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CCC66634.1 - 0.00058 18.7 3.1 0.014 14.2 3.1 3.1 1 1 0 1 1 1 1 Nup133 N terminal like Ge1_WD40 PF16529.5 CCC66634.1 - 0.00071 18.6 0.1 0.45 9.4 0.3 2.4 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 CCC66634.1 - 0.01 15.8 0.0 0.079 12.8 0.0 2.4 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 CCC66634.1 - 0.01 15.2 1.0 0.36 10.1 0.3 2.8 3 0 0 3 3 3 0 WD40-like domain Rrn6 PF10214.9 CCC66634.1 - 0.48 8.9 7.3 0.6 8.5 0.1 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor MRP-L46 PF11788.8 CCC66635.1 - 2.3e-34 118.7 0.0 3.4e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 RRM_1 PF00076.22 CCC66636.1 - 1.7e-05 24.5 0.0 3.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 CCC66636.1 - 0.00037 21.3 0.0 0.0011 19.7 0.0 1.9 1 1 0 1 1 1 1 RNA polymerase II-binding domain. 4_1_CTD PF05902.13 CCC66636.1 - 0.047 13.8 1.1 0.22 11.6 0.2 2.3 2 0 0 2 2 2 0 4.1 protein C-terminal domain (CTD) CTK3 PF12243.8 CCC66636.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 RRM_7 PF16367.5 CCC66636.1 - 0.076 13.1 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Spo7_2_N PF15407.6 CCC66636.1 - 0.077 12.6 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 Sporulation protein family 7 OS-D PF03392.13 CCC66636.1 - 0.18 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D AAA_23 PF13476.6 CCC66637.1 - 7.5e-33 114.7 12.7 7.5e-33 114.7 12.7 8.9 2 1 3 5 5 2 1 AAA domain Rad50_zn_hook PF04423.14 CCC66637.1 - 5.4e-17 61.4 2.2 5.4e-17 61.4 2.2 7.5 7 0 0 7 7 7 1 Rad50 zinc hook motif AAA_21 PF13304.6 CCC66637.1 - 2.7e-09 37.3 2.1 1.5e-05 25.0 0.5 4.8 3 2 2 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CCC66637.1 - 7.9e-09 35.7 10.3 7.9e-09 35.7 10.3 5.4 1 1 3 4 4 2 2 AAA ATPase domain SMC_N PF02463.19 CCC66637.1 - 1.7e-07 30.9 0.1 1.7e-07 30.9 0.1 4.0 2 1 0 2 2 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 CCC66637.1 - 2.8e-06 27.5 0.0 8.8e-06 25.9 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 CCC66637.1 - 0.00046 19.9 0.0 0.0011 18.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.27 CCC66637.1 - 0.014 16.0 0.1 0.014 16.0 0.1 8.3 3 2 2 5 5 3 0 ABC transporter AAA_13 PF13166.6 CCC66637.1 - 0.024 13.3 0.2 0.024 13.3 0.2 7.5 3 1 4 7 7 7 0 AAA domain AAA_16 PF13191.6 CCC66637.1 - 0.097 13.0 0.0 0.097 13.0 0.0 4.1 4 1 0 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 CCC66637.1 - 0.12 12.6 0.1 0.12 12.6 0.1 5.2 3 1 2 5 5 5 0 AAA domain Spc7 PF08317.11 CCC66637.1 - 1.3 7.8 136.5 0.014 14.3 18.5 8.7 3 3 6 9 9 9 0 Spc7 kinetochore protein FGGY_N PF00370.21 CCC66638.1 - 0.0014 18.2 0.1 0.012 15.2 0.1 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Papo_T_antigen PF02380.15 CCC66638.1 - 0.08 13.1 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 T-antigen specific domain RNA_pol_I_A49 PF06870.12 CCC66639.1 - 3.2e-122 408.1 3.6 3.7e-122 407.9 3.6 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor Zwint PF15556.6 CCC66639.1 - 0.06 12.8 1.9 0.33 10.4 0.0 2.5 3 0 0 3 3 3 0 ZW10 interactor tRNA-synt_1e PF01406.19 CCC66640.1 - 8.4e-140 465.3 1.2 8.4e-140 465.3 1.2 2.4 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 CCC66640.1 - 2.4e-06 26.6 7.4 7.9e-05 21.6 0.2 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CCC66640.1 - 0.00038 18.8 0.0 0.00038 18.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) NAP PF00956.18 CCC66641.1 - 5.1e-08 32.4 12.0 1.1e-07 31.4 12.0 1.6 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Cir_N PF10197.9 CCC66642.1 - 1.2e-11 44.6 12.1 1.2e-11 44.6 12.1 3.1 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.8 CCC66642.1 - 1.3e-08 35.6 12.2 1.3e-08 35.6 12.2 2.5 1 1 1 2 2 2 1 Pre-mRNA splicing factor SUI1 PF01253.22 CCC66643.1 - 1.8e-26 92.5 0.5 2.3e-26 92.1 0.5 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 ANTH PF07651.16 CCC66644.1 - 2.9e-72 243.0 0.0 2.9e-72 243.0 0.0 3.6 4 1 1 5 5 5 1 ANTH domain I_LWEQ PF01608.17 CCC66644.1 - 5.2e-51 172.9 7.6 5.2e-51 172.9 7.6 5.5 3 2 2 6 6 6 2 I/LWEQ domain ENTH PF01417.20 CCC66644.1 - 0.00034 20.6 2.1 0.0005 20.1 0.1 2.4 2 0 0 2 2 2 1 ENTH domain DUF812 PF05667.11 CCC66644.1 - 1.3 7.8 51.5 1.1 8.1 34.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ATG_C PF09333.11 CCC66645.1 - 3.8e-32 110.5 0.2 1.1e-31 109.0 0.1 1.9 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain ATG2_CAD PF13329.6 CCC66645.1 - 2.2e-29 102.2 2.9 6.7e-29 100.6 0.4 3.0 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif Chorein_N PF12624.7 CCC66645.1 - 0.00079 19.5 0.5 0.025 14.7 0.2 3.4 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 G6PD_C PF02781.16 CCC66646.1 - 8.4e-107 356.7 0.0 1.1e-106 356.3 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CCC66646.1 - 3e-60 203.9 0.0 4.8e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Fe_hyd_lg_C PF02906.14 CCC66647.1 - 1.3e-56 192.0 0.0 1.8e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Peptidase_S8 PF00082.22 CCC66648.1 - 3e-38 131.8 2.7 6.1e-38 130.8 2.7 1.5 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.20 CCC66648.1 - 1e-25 89.6 0.5 2.5e-25 88.3 0.5 1.7 1 0 0 1 1 1 1 Proprotein convertase P-domain OAD_gamma PF04277.13 CCC66648.1 - 0.66 10.6 2.8 3.7 8.2 0.0 2.4 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ytp1 PF10355.9 CCC66649.1 - 8.7e-59 199.0 20.6 8.8e-57 192.4 20.6 2.4 1 1 0 1 1 1 1 Protein of unknown function (Ytp1) Med16 PF11635.8 CCC66650.1 - 6.2e-194 646.1 16.7 7.2e-194 645.9 16.7 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Cation_efflux PF01545.21 CCC66651.1 - 1.8e-43 148.6 13.6 2.5e-43 148.2 13.6 1.2 1 0 0 1 1 1 1 Cation efflux family Y2_Tnp PF04986.13 CCC66651.1 - 0.044 13.8 0.6 0.044 13.8 0.6 1.7 2 0 0 2 2 2 0 Putative transposase UPF0061 PF02696.14 CCC66653.1 - 4.2e-163 543.4 0.2 5.3e-163 543.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family DAP_B PF07930.12 CCC66653.1 - 0.17 11.9 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 D-aminopeptidase, domain B TRP PF06011.12 CCC66654.1 - 1.7e-158 527.9 34.2 2.2e-158 527.4 34.2 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CCC66654.1 - 1.4e-40 138.9 0.1 2.3e-40 138.2 0.1 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 CCC66654.1 - 0.03 14.8 0.0 0.06 13.8 0.0 1.4 1 0 0 1 1 1 0 ML domain TMEMspv1-c74-12 PF11044.8 CCC66654.1 - 0.037 14.0 2.0 0.052 13.5 0.0 2.3 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Ribosomal_L1 PF00687.21 CCC66655.1 - 9.4e-41 139.8 0.6 1.1e-40 139.5 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cyclin PF08613.11 CCC66656.1 - 5.6e-15 56.1 2.3 1.2e-14 55.0 2.3 1.9 1 1 0 1 1 1 1 Cyclin Arf PF00025.21 CCC66657.1 - 2.2e-49 167.2 0.0 2.4e-49 167.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CCC66657.1 - 1.1e-06 28.1 0.0 2.7e-06 26.8 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit Ras PF00071.22 CCC66657.1 - 2.5e-05 23.9 0.0 2.9e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC66657.1 - 0.0052 17.0 0.0 0.0072 16.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CCC66657.1 - 0.015 14.7 0.0 0.02 14.4 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 CCC66657.1 - 0.03 13.9 0.0 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RIBIOP_C PF04950.12 CCC66658.1 - 1.3e-88 297.2 0.1 1.3e-88 297.2 0.1 3.0 2 1 1 3 3 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CCC66658.1 - 1.3e-29 102.1 0.0 6.9e-29 99.8 0.0 2.4 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 CCC66658.1 - 1e-05 25.2 1.8 0.0077 15.8 0.0 3.5 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA PF00004.29 CCC66658.1 - 1e-05 26.0 0.0 2.6e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CCC66658.1 - 3.4e-05 24.0 0.4 0.00015 21.9 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 CCC66658.1 - 5.9e-05 23.5 0.0 0.0002 21.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCC66658.1 - 0.0013 19.0 0.1 0.0045 17.3 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 CCC66658.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CCC66658.1 - 0.0054 17.1 0.0 0.017 15.5 0.0 1.9 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.22 CCC66658.1 - 0.0056 15.9 0.1 0.02 14.1 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.6 CCC66658.1 - 0.0057 17.0 0.0 0.019 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCC66658.1 - 0.0075 16.8 0.0 0.0075 16.8 0.0 4.4 4 1 0 4 4 3 1 AAA domain AAA_11 PF13086.6 CCC66658.1 - 0.012 15.4 0.2 0.012 15.4 0.2 4.1 3 2 0 3 3 2 0 AAA domain cobW PF02492.19 CCC66658.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 CCC66658.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 CCC66658.1 - 0.014 15.4 0.2 0.084 13.0 0.2 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.6 CCC66658.1 - 0.015 15.6 0.0 0.049 13.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCC66658.1 - 0.016 14.7 0.1 0.042 13.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 CCC66658.1 - 0.019 15.5 1.8 0.043 14.3 0.0 2.6 2 0 0 2 2 1 0 ABC transporter NACHT PF05729.12 CCC66658.1 - 0.021 14.7 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 CCC66658.1 - 0.042 13.7 0.3 0.098 12.6 0.3 1.6 1 0 0 1 1 1 0 NTPase MobB PF03205.14 CCC66658.1 - 0.043 13.7 0.7 0.12 12.3 0.1 2.2 2 1 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 CCC66658.1 - 0.069 12.7 0.0 0.18 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 CCC66658.1 - 0.43 10.3 0.0 0.43 10.3 0.0 2.3 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein WAC_Acf1_DNA_bd PF10537.9 CCC66659.1 - 7.5e-32 109.9 4.6 1.1e-31 109.4 0.4 3.1 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.17 CCC66659.1 - 1.7e-12 47.5 0.4 2e-10 40.8 0.1 2.6 2 0 0 2 2 2 1 DDT domain WSD PF15613.6 CCC66659.1 - 4.3e-11 43.2 3.1 1.7e-10 41.2 0.0 3.5 2 2 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Angiomotin_C PF12240.8 CCC66659.1 - 0.00062 19.4 0.8 0.00062 19.4 0.8 2.4 2 0 0 2 2 2 1 Angiomotin C terminal Ubiq_cyt_C_chap PF03981.12 CCC66660.1 - 3.2e-42 144.0 1.2 5.3e-42 143.3 1.2 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone HK PF02110.15 CCC66661.1 - 3.8e-87 291.7 1.6 5.8e-87 291.2 1.6 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.17 CCC66661.1 - 2.4e-58 196.5 0.0 4.4e-58 195.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase Ysc84 PF04366.12 CCC66661.1 - 0.11 12.3 0.6 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Las17-binding protein actin regulator RNase_P_Rpp14 PF01900.19 CCC66661.1 - 0.16 12.2 0.0 0.43 10.9 0.0 1.7 1 1 0 1 1 1 0 Rpp14/Pop5 family LRR_9 PF14580.6 CCC66662.1 - 9.9e-17 61.0 0.4 1.6e-16 60.3 0.4 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CCC66662.1 - 7.8e-05 23.0 19.8 0.007 16.8 2.0 4.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCC66662.1 - 0.22 11.3 14.2 0.081 12.7 5.0 3.5 1 1 2 3 3 3 0 Leucine rich repeat PseudoU_synth_1 PF01416.20 CCC66663.1 - 2.3e-13 50.5 0.0 1.7e-11 44.5 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 CCC66663.1 - 0.057 13.3 0.7 0.18 11.6 0.0 2.2 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2344) UPF0113_N PF17833.1 CCC66664.1 - 2.4e-29 101.7 0.1 3.4e-29 101.2 0.1 1.2 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 CCC66664.1 - 3.5e-25 88.1 0.0 8.5e-25 86.8 0.0 1.7 2 0 0 2 2 2 1 UPF0113 PUA domain SRP72 PF08492.12 CCC66665.1 - 2.5e-10 40.6 7.2 2.5e-10 40.6 7.2 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain SRP_TPR_like PF17004.5 CCC66665.1 - 2.6e-06 27.4 15.4 6.3e-06 26.2 8.8 4.0 3 2 0 3 3 3 1 Putative TPR-like repeat TPR_19 PF14559.6 CCC66665.1 - 1.7e-05 25.2 5.1 0.023 15.2 0.4 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCC66665.1 - 0.0013 18.7 17.0 0.081 13.1 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCC66665.1 - 0.0013 18.9 7.5 0.095 13.0 0.5 4.1 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 CCC66665.1 - 0.0041 17.7 4.4 0.97 10.2 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCC66665.1 - 0.042 14.7 0.9 51 5.1 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCC66665.1 - 0.11 12.5 4.8 3.5 7.9 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCC66665.1 - 3.3 7.7 13.1 2.9 7.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SET PF00856.28 CCC66666.1 - 5.7e-05 23.6 1.0 0.00011 22.7 0.0 1.9 2 1 0 2 2 2 1 SET domain DUF421 PF04239.12 CCC66666.1 - 0.073 12.8 0.0 0.61 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF421) Wyosine_form PF08608.12 CCC66667.1 - 1.6e-23 82.8 0.0 3.4e-23 81.8 0.0 1.6 1 0 0 1 1 1 1 Wyosine base formation Radical_SAM PF04055.21 CCC66667.1 - 6.6e-21 75.4 0.0 1.2e-20 74.5 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Flavodoxin_1 PF00258.25 CCC66667.1 - 1.6e-15 57.5 0.0 3.7e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin GDPD PF03009.17 CCC66668.1 - 1.4e-32 113.5 0.0 2.3e-32 112.7 0.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Pkinase PF00069.25 CCC66669.1 - 4e-24 85.4 0.0 7.4e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC66669.1 - 1.1e-10 41.2 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC66669.1 - 1.2e-07 30.9 0.2 2.3e-07 29.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase LRIF1 PF15741.5 CCC66669.1 - 0.058 11.9 1.3 0.075 11.6 1.3 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 DUF4085 PF13315.6 CCC66669.1 - 0.062 12.9 1.9 0.12 12.0 0.8 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) GPS2_interact PF15784.5 CCC66669.1 - 5.4 7.5 8.3 0.15 12.5 1.5 1.9 2 0 0 2 2 2 0 G-protein pathway suppressor 2-interacting domain Pkinase PF00069.25 CCC66670.1 - 2.1e-70 237.1 0.0 2.5e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC66670.1 - 3.5e-41 141.2 0.0 4.6e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC66670.1 - 5.9e-06 25.8 0.1 1.5e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CCC66670.1 - 0.048 12.6 0.5 0.12 11.3 0.5 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Seadorna_VP7 PF07387.11 CCC66670.1 - 0.12 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 AFT PF08731.11 CCC66671.1 - 1.4e-35 122.1 5.7 1.4e-35 122.1 5.7 3.8 3 1 0 3 3 3 1 Transcription factor AFT DBD_Tnp_Mut PF03108.15 CCC66671.1 - 0.47 10.5 2.3 15 5.6 0.0 2.7 2 1 1 3 3 3 0 MuDR family transposase Lectin_C PF00059.21 CCC66672.1 - 0.039 14.7 3.8 0.29 11.9 0.0 3.2 3 1 1 4 4 4 0 Lectin C-type domain DUF1771 PF08590.10 CCC66673.1 - 2.7e-15 56.5 8.9 4.5e-15 55.8 8.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 CCC66673.1 - 2.2e-09 37.5 0.0 4.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Smr domain CYSTM PF12734.7 CCC66673.1 - 0.0019 18.5 5.4 0.0042 17.4 5.4 1.6 1 0 0 1 1 1 1 Cysteine-rich TM module stress tolerance DUF1798 PF08807.10 CCC66673.1 - 0.0049 17.0 1.0 0.016 15.3 0.1 2.1 1 1 1 2 2 2 1 Bacterial domain of unknown function (DUF1798) SMBP PF16785.5 CCC66673.1 - 0.13 12.5 4.7 0.17 12.1 1.6 2.1 2 0 0 2 2 2 0 Small metal-binding protein HIM1 PF08732.10 CCC66674.1 - 0.0042 16.6 0.2 0.029 13.9 0.1 2.1 2 0 0 2 2 2 1 HIM1 TLD PF07534.16 CCC66675.1 - 1.8e-28 99.5 0.1 1.7e-27 96.3 0.1 2.0 1 1 0 1 1 1 1 TLD Adaptin_N PF01602.20 CCC66676.1 - 1.6e-114 383.4 17.5 2.2e-114 382.9 17.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCC66676.1 - 8.1e-13 48.7 12.3 2.8e-12 47.0 0.3 3.4 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCC66676.1 - 4.3e-07 29.6 1.0 17 6.0 0.0 6.7 6 1 0 6 6 6 2 HEAT repeat Cnd3 PF12719.7 CCC66676.1 - 0.00024 20.4 5.2 0.0038 16.5 0.1 3.7 2 2 2 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CCC66676.1 - 0.0011 19.3 0.0 0.85 10.1 0.0 4.2 3 2 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 CCC66676.1 - 0.0089 16.5 0.8 50 4.5 0.1 5.7 6 1 0 6 6 6 0 HEAT-like repeat RTP1_C1 PF10363.9 CCC66676.1 - 0.01 16.0 0.9 4.8 7.4 0.0 3.5 3 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Telomere_reg-2 PF10193.9 CCC66676.1 - 0.87 10.1 4.5 3.4 8.2 0.0 4.0 5 1 0 5 5 5 0 Telomere length regulation protein TENA_THI-4 PF03070.16 CCC66677.1 - 2.8e-10 40.4 0.8 4e-10 39.9 0.8 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Dynamin_M PF01031.20 CCC66678.1 - 3.7e-107 357.8 0.1 6.9e-107 356.9 0.1 1.5 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 CCC66678.1 - 5.1e-55 186.1 5.3 1.3e-54 184.8 0.0 3.0 2 1 0 2 2 2 1 Dynamin family GED PF02212.18 CCC66678.1 - 1.4e-29 102.1 3.6 4.3e-29 100.5 3.6 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CCC66678.1 - 6.6e-05 23.0 0.7 0.00059 19.9 0.7 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase MRNIP PF15749.5 CCC66678.1 - 0.81 10.4 4.3 25 5.7 0.0 2.7 2 0 0 2 2 2 0 MRN-interacting protein Fasciclin PF02469.22 CCC66679.1 - 8.6e-18 64.8 5.6 0.00043 20.5 0.0 5.9 5 1 0 5 5 5 5 Fasciclin domain dCMP_cyt_deam_1 PF00383.23 CCC66680.1 - 2.1e-23 82.1 0.1 2.9e-23 81.7 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCC66680.1 - 6.3e-18 64.8 0.0 9.1e-18 64.3 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 CCC66680.1 - 0.00015 21.6 0.0 0.00025 20.9 0.0 1.3 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase Bd3614-deam PF14439.6 CCC66680.1 - 0.00075 19.6 0.2 0.0027 17.8 0.2 1.9 1 1 0 1 1 1 1 Bd3614-like deaminase SNAD4 PF18750.1 CCC66680.1 - 0.016 15.4 0.0 0.026 14.6 0.0 1.3 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 NAD1 PF18778.1 CCC66680.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Novel AID APOBEC clade 1 HSP70 PF00012.20 CCC66681.1 - 8e-262 869.8 13.8 9.1e-262 869.6 13.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCC66681.1 - 1.2e-19 70.4 2.1 2.6e-18 65.9 0.4 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CCC66681.1 - 0.0017 18.8 5.1 0.67 10.4 0.2 3.7 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 CCC66681.1 - 0.0017 17.6 0.7 0.07 12.4 0.0 2.9 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.20 CCC66681.1 - 0.0019 17.7 0.3 0.05 13.1 0.3 2.3 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Radial_spoke_3 PF06098.11 CCC66681.1 - 0.044 13.1 0.8 0.083 12.1 0.8 1.4 1 0 0 1 1 1 0 Radial spoke protein 3 DUF5300 PF17224.3 CCC66681.1 - 1 9.6 5.7 14 6.0 0.1 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5300) RRF PF01765.19 CCC66682.1 - 4.1e-35 121.1 6.8 4.1e-35 121.1 6.8 1.4 2 0 0 2 2 2 1 Ribosome recycling factor CHIP_TPR_N PF18391.1 CCC66682.1 - 0.039 14.7 1.4 0.039 14.7 1.4 2.0 2 1 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain NPV_P10 PF05531.12 CCC66682.1 - 0.069 13.6 1.3 0.21 12.1 1.3 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 CCC66682.1 - 0.07 13.4 6.5 0.75 10.0 2.4 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain FliD_C PF07195.12 CCC66682.1 - 0.33 10.3 10.4 1.2 8.5 9.4 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus TSP_NTD PF17804.1 CCC66682.1 - 0.74 10.0 8.8 0.43 10.8 2.7 2.2 2 0 0 2 2 2 0 Tail specific protease N-terminal domain Fib_alpha PF08702.10 CCC66682.1 - 1.6 8.9 6.9 0.94 9.7 2.0 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Aldedh PF00171.22 CCC66683.1 - 1.4e-122 409.5 0.0 1.7e-122 409.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family V-ATPase_G PF03179.15 CCC66684.1 - 5.5e-31 107.2 11.3 6.2e-31 107.0 11.3 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.18 CCC66684.1 - 0.0039 17.3 11.8 0.014 15.4 11.8 1.8 1 1 0 1 1 1 1 ATP synthase B/B' CF(0) S_layer_C PF05124.12 CCC66684.1 - 0.014 15.4 4.6 0.017 15.1 4.6 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region V-ATPase_G_2 PF16999.5 CCC66684.1 - 0.045 14.2 9.8 0.059 13.8 9.8 1.2 1 0 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 CCC66684.1 - 0.075 12.4 15.8 0.13 11.7 7.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) ASL_C2 PF14698.6 CCC66684.1 - 0.15 12.8 1.1 0.29 11.9 1.1 1.7 1 1 0 1 1 1 0 Argininosuccinate lyase C-terminal Med20 PF08612.11 CCC66685.1 - 7.5e-30 104.0 0.0 9e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex LSM PF01423.22 CCC66685.1 - 0.095 12.4 0.1 0.31 10.7 0.1 2.0 1 1 0 1 1 1 0 LSM domain THDPS_N_2 PF14805.6 CCC66685.1 - 0.12 12.7 0.0 1 9.7 0.0 2.1 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal FAD_binding_1 PF00667.20 CCC66686.1 - 3.1e-67 226.4 0.2 5e-67 225.7 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CCC66686.1 - 1.4e-29 103.1 0.2 2.9e-29 102.1 0.2 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CCC66686.1 - 2.5e-21 76.3 0.0 7.4e-21 74.8 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF2732 PF10809.8 CCC66686.1 - 0.072 13.0 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) HAD_2 PF13419.6 CCC66687.1 - 1.9e-18 67.2 0.0 3e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCC66687.1 - 4.5e-08 33.6 0.0 2.4e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCC66687.1 - 0.018 15.1 0.1 0.037 14.1 0.1 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like CDI PF02234.19 CCC66687.1 - 0.042 14.0 0.7 0.74 10.1 0.1 2.3 1 1 1 2 2 2 0 Cyclin-dependent kinase inhibitor HAD PF12710.7 CCC66687.1 - 0.12 12.7 0.0 0.23 11.9 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCC66688.1 - 2.1e-14 54.0 0.0 2.9e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCC66688.1 - 3.6e-09 37.2 0.0 3.4e-08 34.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase RabGAP-TBC PF00566.18 CCC66689.1 - 1.5e-15 57.4 1.4 1.5e-15 57.4 1.4 2.3 1 1 1 2 2 2 1 Rab-GTPase-TBC domain Fe-S_biosyn PF01521.20 CCC66689.1 - 0.12 12.6 0.0 0.34 11.1 0.0 1.8 1 0 0 1 1 1 0 Iron-sulphur cluster biosynthesis Nsp1_C PF05064.13 CCC66691.1 - 1.3e-40 137.8 4.9 1.3e-40 137.8 4.9 2.0 1 1 1 2 2 2 1 Nsp1-like C-terminal region DNA_primase_lrg PF04104.14 CCC66691.1 - 0.11 11.9 0.9 0.22 10.9 0.9 1.6 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit Laminin_II PF06009.12 CCC66691.1 - 0.69 9.9 13.4 3 7.8 8.0 2.7 1 1 0 2 2 2 0 Laminin Domain II DUF16 PF01519.16 CCC66691.1 - 2.9 8.4 9.5 0.17 12.4 1.8 2.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 APG6_N PF17675.1 CCC66691.1 - 2.9 8.4 11.2 6.7 7.3 11.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region XhlA PF10779.9 CCC66691.1 - 6.9 7.0 6.0 22 5.3 0.1 3.3 2 1 1 3 3 3 0 Haemolysin XhlA Nup192 PF11894.8 CCC66692.1 - 0 1661.9 75.5 0 1661.8 75.5 1.0 1 0 0 1 1 1 1 Nuclear pore complex scaffold, nucleoporins 186/192/205 Ppx-GppA PF02541.16 CCC66692.1 - 0.024 14.1 0.1 0.095 12.1 0.0 2.0 2 0 0 2 2 2 0 Ppx/GppA phosphatase family AA_kinase PF00696.28 CCC66693.1 - 4.5e-35 121.4 0.6 6.2e-35 120.9 0.6 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 CCC66693.1 - 3e-13 49.5 0.0 7.3e-13 48.3 0.0 1.7 1 0 0 1 1 1 1 PUA domain DUF1930 PF09122.10 CCC66693.1 - 0.0069 16.4 0.4 0.046 13.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1930) Pih1_fungal_CS PF18482.1 CCC66694.1 - 4.2e-31 107.3 6.0 7.4e-31 106.5 6.0 1.4 1 0 0 1 1 1 1 Fungal Pih1 CS domain PIH1 PF08190.12 CCC66694.1 - 3.2e-29 101.5 0.2 5.8e-29 100.7 0.2 1.4 1 0 0 1 1 1 1 PIH1 N-terminal domain FA_hydroxylase PF04116.13 CCC66695.1 - 3.4e-22 79.2 7.3 3.4e-22 79.2 7.3 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily HAUS6_N PF14661.6 CCC66695.1 - 0.14 11.7 0.6 0.28 10.7 0.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Sec23_trunk PF04811.15 CCC66696.1 - 4.9e-14 52.5 0.1 6.4e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Aldedh PF00171.22 CCC66697.1 - 3.7e-97 325.7 0.0 4.4e-97 325.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DEAD PF00270.29 CCC66698.1 - 3.2e-47 160.6 0.0 1.1e-46 158.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC66698.1 - 3.4e-24 85.3 0.0 1e-23 83.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCC66698.1 - 1.4e-20 73.2 0.0 3.4e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCC66698.1 - 9.9e-05 22.4 0.0 9.9e-05 22.4 0.0 2.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Gluconate_2-dh3 PF13618.6 CCC66698.1 - 0.75 10.0 3.4 16 5.7 0.7 2.9 3 0 0 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 DUF5338 PF17273.2 CCC66698.1 - 3.5 7.8 5.4 47 4.2 0.0 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5338) HORMA PF02301.18 CCC66699.1 - 1.3e-22 80.5 0.0 5e-22 78.5 0.0 1.7 1 1 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 CCC66699.1 - 0.07 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial HORMA domain 2 NOC3p PF07540.11 CCC66700.1 - 3.7e-30 104.2 0.3 3.7e-30 104.2 0.3 3.6 3 1 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 CCC66700.1 - 6.1e-23 81.7 0.1 6.1e-23 81.7 0.1 3.2 2 1 0 3 3 3 1 CBF/Mak21 family RNA_pol_Rpb2_3 PF04565.16 CCC66700.1 - 0.085 13.0 0.0 0.38 11.0 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 3 Candida_ALS_N PF11766.8 CCC66701.1 - 5.3e-73 245.3 3.7 5.3e-73 245.3 3.7 2.9 2 1 0 3 3 3 1 Cell-wall agglutinin N-terminal ligand-sugar binding Flocculin PF00624.18 CCC66701.1 - 1.6e-33 114.7 146.5 4.2e-10 39.7 31.0 10.5 8 2 2 10 10 10 4 Flocculin repeat DUF2318 PF10080.9 CCC66701.1 - 0.091 12.9 0.1 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) ColG_sub PF18496.1 CCC66701.1 - 0.36 11.0 11.8 2.6 8.2 1.7 3.3 1 1 2 3 3 3 0 Collagenase G catalytic helper subdomain CMS1 PF14617.6 CCC66702.1 - 1.8e-15 57.0 15.3 2.1e-11 43.6 6.2 3.0 1 1 2 3 3 3 2 U3-containing 90S pre-ribosomal complex subunit RED_C PF07807.11 CCC66702.1 - 0.0095 16.4 4.8 0.21 12.1 0.2 2.4 2 0 0 2 2 2 2 RED-like protein C-terminal region HTH_Tnp_1_2 PF13022.6 CCC66702.1 - 0.059 13.5 3.2 0.39 10.9 0.9 2.8 3 0 0 3 3 3 0 Helix-turn-helix of insertion element transposase SMC_Nse1 PF07574.13 CCC66703.1 - 3.5e-57 193.4 0.1 4.5e-57 193.1 0.1 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 CCC66703.1 - 3e-13 49.8 11.2 6.2e-13 48.8 11.2 1.6 1 0 0 1 1 1 1 RING-like domain SNF2_assoc PF08455.10 CCC66703.1 - 0.051 12.6 0.0 0.086 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated Ribosomal_L24e PF01246.20 CCC66704.1 - 2.3e-32 111.0 3.8 2.3e-32 111.0 3.8 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e AAA_23 PF13476.6 CCC66704.1 - 1.3 9.5 12.1 1.6 9.2 12.1 1.2 1 0 0 1 1 1 0 AAA domain SEP PF08059.13 CCC66705.1 - 0.14 12.7 0.1 9.3 6.9 0.0 3.1 3 1 0 3 3 3 0 SEP domain DUF2059 PF09832.9 CCC66705.1 - 0.15 12.2 0.0 0.29 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) Proteasome PF00227.26 CCC66706.1 - 3.2e-47 160.5 1.3 3.6e-47 160.3 1.3 1.0 1 0 0 1 1 1 1 Proteasome subunit Sfi1_C PF10638.9 CCC66707.1 - 6e-23 81.6 5.9 4.5e-22 78.8 5.9 2.6 1 0 0 1 1 1 1 Spindle body associated protein C-terminus Sfi1 PF08457.10 CCC66707.1 - 1.3e-19 70.2 71.1 4.6e-18 65.1 56.7 3.1 1 1 2 3 3 3 3 Sfi1 spindle body protein Reticulon PF02453.17 CCC66707.1 - 1 9.3 5.0 25 4.8 0.1 3.5 4 0 0 4 4 4 0 Reticulon Ribophorin_I PF04597.14 CCC66708.1 - 3.1e-122 409.0 2.2 3.5e-122 408.8 2.2 1.0 1 0 0 1 1 1 1 Ribophorin I ORC_WH_C PF18137.1 CCC66709.1 - 6.3e-24 84.6 0.0 1.1e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 Origin recognition complex winged helix C-terminal MIT_C PF16565.5 CCC66709.1 - 0.27 11.2 2.5 3 7.8 0.0 3.1 3 0 0 3 3 3 0 Phospholipase D-like domain at C-terminus of MIT RSN1_7TM PF02714.15 CCC66710.1 - 3.2e-70 236.6 23.8 3.2e-70 236.6 23.8 2.4 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CCC66710.1 - 2.5e-29 102.1 2.4 2.5e-29 102.1 2.4 2.6 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CCC66710.1 - 2.5e-05 24.6 0.0 5.6e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Cytochrome-c551 PF10643.9 CCC66710.1 - 0.065 12.8 0.2 0.21 11.2 0.2 1.8 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 MMM1 PF10296.9 CCC66711.1 - 9.5e-136 452.2 5.0 1.1e-135 451.9 5.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 PH_12 PF16457.5 CCC66712.1 - 7e-08 33.1 2.7 1.1e-06 29.3 0.2 3.3 3 1 0 3 3 3 1 Pleckstrin homology domain DEAD PF00270.29 CCC66713.1 - 5.1e-47 159.9 0.1 1e-46 158.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC66713.1 - 8.5e-30 103.4 0.2 1.3e-28 99.6 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 CCC66713.1 - 0.004 17.5 0.1 0.024 15.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCC66713.1 - 0.04 14.2 0.5 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain COX17 PF05051.13 CCC66714.1 - 1.8e-21 76.2 6.5 1.8e-21 76.2 6.5 1.5 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 CCC66714.1 - 0.031 14.3 10.1 0.18 11.8 0.1 2.6 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DPPIV_N PF00930.21 CCC66715.1 - 1.5e-102 343.0 3.5 2.2e-102 342.4 3.5 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CCC66715.1 - 5.4e-51 173.1 2.4 8.1e-51 172.5 2.4 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 CCC66715.1 - 0.0021 18.7 0.0 0.024 15.2 0.0 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase family DUF5502 PF17606.2 CCC66715.1 - 0.0051 17.5 0.1 0.024 15.3 0.0 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5502) Abhydrolase_2 PF02230.16 CCC66715.1 - 0.059 13.2 0.1 15 5.3 0.1 2.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 CCC66715.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold PD40 PF07676.12 CCC66715.1 - 0.12 12.3 1.6 0.47 10.5 0.2 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SL4P PF17618.2 CCC66715.1 - 0.41 10.7 3.7 0.38 10.8 0.2 2.7 3 0 0 3 3 3 0 Uncharacterized Strongylid L4 protein Med6 PF04934.14 CCC66716.1 - 5.2e-52 175.2 0.6 8e-52 174.6 0.6 1.3 1 0 0 1 1 1 1 MED6 mediator sub complex component IGR PF09597.10 CCC66717.1 - 3.7e-22 78.2 0.1 9.6e-22 76.9 0.1 1.7 2 0 0 2 2 2 1 IGR protein motif PBD PF00786.28 CCC66719.1 - 0.065 13.6 0.2 0.17 12.2 0.2 1.7 1 0 0 1 1 1 0 P21-Rho-binding domain DUF3675 PF12428.8 CCC66720.1 - 0.17 12.5 0.1 0.38 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Fungal_trans PF04082.18 CCC66721.1 - 2.8e-29 102.0 10.0 3.2e-28 98.5 7.7 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC66721.1 - 8.7e-09 35.4 17.7 2.2e-08 34.1 17.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.26 CCC66722.1 - 7.9e-47 159.2 0.0 1.2e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCC66722.1 - 2.1e-15 56.1 0.1 3.8e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF962 PF06127.11 CCC66723.1 - 1.1e-24 86.3 2.2 3.2e-24 84.8 2.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Tht1 PF04163.12 CCC66723.1 - 0.01 14.6 3.0 0.013 14.3 3.0 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Aconitase PF00330.20 CCC66724.1 - 7.4e-159 529.6 0.1 9.7e-159 529.2 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCC66724.1 - 3e-45 153.7 0.0 5.7e-45 152.8 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ATE_C PF04377.15 CCC66726.1 - 1.1e-43 149.0 0.9 2.5e-43 147.9 0.9 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 CCC66726.1 - 2.2e-26 92.1 0.8 4.6e-26 91.0 0.8 1.6 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus RGS PF00615.19 CCC66726.1 - 0.019 15.3 0.9 0.04 14.2 0.5 1.7 2 0 0 2 2 2 0 Regulator of G protein signaling domain HSCB_C PF07743.13 CCC66727.1 - 3.1e-20 72.5 6.4 1.9e-19 69.9 2.6 2.3 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 CCC66727.1 - 3.2e-09 36.8 1.5 4.7e-09 36.2 0.3 1.9 2 0 0 2 2 2 1 DnaJ domain Cnl2_NKP2 PF09447.10 CCC66727.1 - 0.06 13.5 1.2 0.11 12.6 0.3 2.0 2 0 0 2 2 2 0 Cnl2/NKP2 family protein VGCC_beta4Aa_N PF12052.8 CCC66727.1 - 0.14 12.3 0.4 0.33 11.1 0.4 1.6 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Arm-DNA-bind_5 PF17293.2 CCC66727.1 - 1.1 9.7 4.7 3.4 8.2 3.4 2.5 1 1 0 1 1 1 0 Arm DNA-binding domain CK_II_beta PF01214.18 CCC66728.1 - 2.5e-68 229.5 0.1 3.9e-68 228.9 0.1 1.3 1 1 0 1 1 1 1 Casein kinase II regulatory subunit CHD5 PF04420.14 CCC66729.1 - 2.9e-50 170.2 1.6 3.7e-50 169.9 1.6 1.1 1 0 0 1 1 1 1 CHD5-like protein STT3 PF02516.14 CCC66730.1 - 7.3e-150 500.1 50.2 1.6e-147 492.4 46.4 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit FYVE PF01363.21 CCC66731.1 - 2.7e-15 56.3 7.8 5.7e-15 55.2 7.8 1.6 1 0 0 1 1 1 1 FYVE zinc finger HypA PF01155.19 CCC66731.1 - 0.12 12.5 0.9 0.35 10.9 0.9 1.8 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA mRNA_decap_C PF16741.5 CCC66732.1 - 0.042 13.2 0.5 0.1 11.9 0.5 1.8 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus Glyco_hydro_63 PF03200.16 CCC66734.1 - 2.6e-172 574.0 3.0 1.8e-171 571.2 3.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 CCC66734.1 - 9.5e-61 205.8 0.0 1.6e-60 205.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 N-terminal domain GDE_C PF06202.14 CCC66734.1 - 0.015 14.3 0.0 0.024 13.6 0.0 1.4 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Glyco_hydro_36 PF17167.4 CCC66734.1 - 0.015 14.0 0.0 0.025 13.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain DUF3841 PF12952.7 CCC66734.1 - 0.14 11.9 1.8 0.25 11.1 0.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3841) Macoilin PF09726.9 CCC66735.1 - 0.42 9.1 4.9 0.5 8.9 4.9 1.1 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CCC66735.1 - 0.96 9.4 13.4 1.7 8.6 13.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_L7Ae PF01248.26 CCC66736.1 - 1.4e-24 85.7 0.1 1.5e-24 85.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L24e PF01246.20 CCC66737.1 - 2.2e-29 101.5 0.2 2.2e-29 101.5 0.2 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e UNC-79 PF14776.6 CCC66737.1 - 0.2 10.4 1.0 0.24 10.1 1.0 1.0 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 AGA2 PF17366.2 CCC66738.1 - 1.4e-23 82.3 6.8 1.8e-23 81.9 6.8 1.1 1 0 0 1 1 1 1 A-agglutinin-binding subunit Aga2 MF_alpha_N PF05436.11 CCC66738.1 - 0.0021 17.9 1.0 0.1 12.5 1.0 2.2 1 1 0 1 1 1 1 Mating factor alpha precursor N-terminus TBPIP PF07106.13 CCC66739.1 - 6.3e-21 74.1 0.4 6.3e-21 74.1 0.4 1.7 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain Seryl_tRNA_N PF02403.22 CCC66739.1 - 0.039 14.2 0.1 0.039 14.2 0.1 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain ZapB PF06005.12 CCC66739.1 - 0.046 14.2 1.4 0.046 14.2 1.4 1.9 2 0 0 2 2 2 0 Cell division protein ZapB YkyA PF10368.9 CCC66739.1 - 0.046 13.4 1.7 0.09 12.4 1.7 1.5 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein Syntaxin_2 PF14523.6 CCC66739.1 - 1.7 9.0 8.4 3.4 8.1 1.1 2.9 1 1 1 2 2 2 0 Syntaxin-like protein zf-H2C2_2 PF13465.6 CCC66740.1 - 7.4e-09 35.6 13.2 1.2e-05 25.5 3.6 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CCC66740.1 - 3.7e-07 30.2 15.1 0.0034 17.8 1.6 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC66740.1 - 0.0012 19.5 12.7 0.11 13.3 4.5 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger Ecl1 PF12855.7 CCC66741.1 - 1.4e-06 29.6 11.7 0.0053 17.9 6.7 2.2 2 0 0 2 2 2 2 ECL1/2/3 zinc binding proteins V-SNARE_C PF12352.8 CCC66742.1 - 0.033 14.5 8.5 0.48 10.8 0.2 3.2 4 0 0 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus NUC153 PF08159.12 CCC66743.1 - 3.4e-11 42.8 2.7 7.7e-11 41.6 2.7 1.7 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 CCC66743.1 - 0.015 15.6 0.0 0.1 12.9 0.0 2.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCC66743.1 - 0.096 13.6 0.3 22 6.1 0.0 3.7 4 0 0 4 4 4 0 WD domain, G-beta repeat Isochorismatase PF00857.20 CCC66745.1 - 1.5e-28 100.1 0.0 2.3e-28 99.6 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Ish1 PF10281.9 CCC66745.1 - 0.036 14.4 0.9 9.2 6.7 0.1 2.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Gly_transf_sug PF04488.15 CCC66746.1 - 4.3e-13 49.7 0.0 1.3e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ras PF00071.22 CCC66747.1 - 2.9e-50 170.0 0.0 4.8e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC66747.1 - 1.3e-16 60.9 0.8 2.8e-16 59.8 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC66747.1 - 1.4e-07 31.2 0.1 2e-07 30.6 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCC66747.1 - 5.9e-06 26.0 0.0 5.9e-06 26.0 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCC66747.1 - 0.00036 20.5 0.0 0.65 9.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase Velvet PF11754.8 CCC66747.1 - 0.086 12.8 7.0 0.1 12.5 7.0 1.1 1 0 0 1 1 1 0 Velvet factor SRP-alpha_N PF04086.13 CCC66747.1 - 0.47 10.3 13.6 0.77 9.6 13.6 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Mem_trans PF03547.18 CCC66747.1 - 2.1 6.7 6.1 3 6.1 6.1 1.2 1 0 0 1 1 1 0 Membrane transport protein DDHD PF02862.17 CCC66747.1 - 6.8 6.8 11.9 10 6.2 11.9 1.2 1 0 0 1 1 1 0 DDHD domain PRC2_HTH_1 PF18118.1 CCC66747.1 - 8.2 7.3 14.1 87 4.0 14.1 2.2 1 1 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain ALAD PF00490.21 CCC66748.1 - 1.4e-119 399.0 0.0 1.7e-119 398.7 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Pyridox_oxase_2 PF12766.7 CCC66749.1 - 2.5e-30 105.0 0.1 3.8e-30 104.4 0.1 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TGF_beta PF00019.20 CCC66749.1 - 0.12 13.4 0.1 0.25 12.4 0.1 1.5 1 0 0 1 1 1 0 Transforming growth factor beta like domain Aminotran_3 PF00202.21 CCC66750.1 - 5.3e-98 328.3 0.0 6.6e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ATP-synt_F PF01990.17 CCC66751.1 - 7.5e-31 106.3 0.2 9.2e-31 106.0 0.2 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit RRP7 PF12923.7 CCC66751.1 - 0.059 13.5 0.0 0.087 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Transcrip_reg PF01709.20 CCC66752.1 - 4.5e-64 216.1 4.5 5.2e-64 215.9 4.5 1.0 1 0 0 1 1 1 1 Transcriptional regulator Mid2 PF04478.12 CCC66753.1 - 9.9e-62 207.2 5.2 9.9e-62 207.2 5.2 2.1 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 CCC66753.1 - 0.072 12.5 0.0 0.28 10.6 0.0 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2737 PF10930.8 CCC66754.1 - 0.08 12.5 0.2 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2737) AAA PF00004.29 CCC66757.1 - 1.4e-37 129.1 0.0 2.5e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC66757.1 - 3.1e-12 46.1 0.0 7.8e-12 44.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 CCC66757.1 - 2.4e-06 27.4 0.0 7.3e-06 25.8 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CCC66757.1 - 2.6e-06 27.7 0.0 6.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCC66757.1 - 3.4e-06 27.5 0.0 0.00017 22.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CCC66757.1 - 3.6e-06 27.0 0.2 9.4e-05 22.4 0.2 2.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 CCC66757.1 - 4.7e-06 26.7 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCC66757.1 - 7.3e-05 23.1 0.9 0.0013 19.0 0.0 2.8 3 1 1 4 4 3 1 AAA domain AAA_33 PF13671.6 CCC66757.1 - 0.00014 22.1 0.0 0.00036 20.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCC66757.1 - 0.00022 21.7 0.0 0.0006 20.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain Sigma54_activ_2 PF14532.6 CCC66757.1 - 0.00035 20.7 0.0 0.00071 19.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 CCC66757.1 - 0.00047 19.9 0.0 0.00084 19.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 CCC66757.1 - 0.00049 19.5 0.2 0.0016 17.9 0.2 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CCC66757.1 - 0.0008 19.2 0.0 0.0088 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCC66757.1 - 0.0011 19.4 0.0 0.0032 17.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase TniB PF05621.11 CCC66757.1 - 0.0012 18.3 0.0 0.8 9.1 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_7 PF12775.7 CCC66757.1 - 0.0025 17.3 0.0 0.011 15.3 0.0 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region Rad17 PF03215.15 CCC66757.1 - 0.0028 17.6 0.1 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 Rad17 P-loop domain Sigma54_activat PF00158.26 CCC66757.1 - 0.005 16.6 0.0 0.015 15.0 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.27 CCC66757.1 - 0.0051 17.3 0.0 0.013 16.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.13 CCC66757.1 - 0.0055 15.9 0.0 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.12 CCC66757.1 - 0.0056 16.6 0.0 0.014 15.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.12 CCC66757.1 - 0.011 15.1 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 CCC66757.1 - 0.013 15.1 0.2 0.057 13.0 0.1 1.9 2 0 0 2 2 2 0 AAA domain KAP_NTPase PF07693.14 CCC66757.1 - 0.018 14.3 0.3 0.67 9.1 0.0 2.4 1 1 1 2 2 2 0 KAP family P-loop domain Hydin_ADK PF17213.3 CCC66757.1 - 0.019 15.3 0.2 2.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain AAA_28 PF13521.6 CCC66757.1 - 0.02 15.2 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 CCC66757.1 - 0.023 14.6 0.0 0.045 13.6 0.0 1.5 1 1 0 1 1 1 0 Bacterial dnaA protein ATPase_2 PF01637.18 CCC66757.1 - 0.027 14.4 0.0 0.093 12.6 0.0 1.8 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 CCC66757.1 - 0.028 14.8 0.1 0.096 13.1 0.0 1.9 2 0 0 2 2 1 0 AAA domain TIP49 PF06068.13 CCC66757.1 - 0.03 13.5 0.1 0.062 12.5 0.0 1.5 1 1 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 CCC66757.1 - 0.041 13.8 0.0 0.084 12.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 CCC66757.1 - 0.043 12.9 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Viral_helicase1 PF01443.18 CCC66757.1 - 0.055 13.2 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase FCH PF00611.23 CCC66757.1 - 0.064 13.6 0.1 0.95 9.8 0.0 2.4 2 0 0 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain TsaE PF02367.17 CCC66757.1 - 0.076 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CPT PF07931.12 CCC66757.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Evr1_Alr PF04777.13 CCC66758.1 - 2.1e-28 98.7 4.4 3.4e-28 98.0 4.4 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Alba PF01918.21 CCC66759.1 - 7e-09 35.4 0.1 1e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 Alba Ribosomal_L10 PF00466.20 CCC66760.1 - 1e-23 83.4 0.2 1.7e-23 82.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 CCC66760.1 - 5.7e-21 74.3 0.0 9.3e-21 73.6 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_60s PF00428.19 CCC66760.1 - 4.1e-19 68.9 2.7 4.1e-19 68.9 2.7 2.1 2 0 0 2 2 2 1 60s Acidic ribosomal protein Abhydrolase_1 PF00561.20 CCC66761.1 - 1e-24 87.6 0.0 3.9e-24 85.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCC66761.1 - 1.3e-11 44.3 0.0 2.3e-11 43.4 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCC66761.1 - 4.6e-11 43.8 0.0 1.3e-10 42.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CCC66761.1 - 0.0024 17.6 0.2 0.011 15.5 0.1 2.1 1 1 1 2 2 2 1 PGAP1-like protein LIDHydrolase PF10230.9 CCC66761.1 - 0.0073 15.9 0.2 0.018 14.6 0.1 1.7 1 1 1 2 2 2 1 Lipid-droplet associated hydrolase Thioesterase PF00975.20 CCC66761.1 - 0.014 15.6 0.0 0.042 13.9 0.0 1.8 2 0 0 2 2 2 0 Thioesterase domain DUF676 PF05057.14 CCC66761.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Glucan_synthase PF02364.15 CCC66762.1 - 0 1351.3 0.3 0 1350.2 0.0 1.7 2 0 0 2 2 2 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CCC66762.1 - 3.5e-43 147.0 3.6 9.8e-43 145.6 1.1 2.6 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 TIM21 PF08294.11 CCC66763.1 - 1.4e-55 187.1 0.1 1.9e-55 186.7 0.1 1.2 1 0 0 1 1 1 1 TIM21 Secretin_N_2 PF07655.13 CCC66763.1 - 0.006 17.1 0.5 0.011 16.2 0.5 1.4 1 0 0 1 1 1 1 Secretin N-terminal domain Ribosomal_L26 PF16906.5 CCC66764.1 - 3e-37 126.9 2.6 4.7e-37 126.3 2.6 1.3 1 1 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CCC66764.1 - 2.3e-05 24.2 1.6 2.6e-05 24.0 0.5 1.7 2 0 0 2 2 2 1 KOW motif His_Phos_1 PF00300.22 CCC66765.1 - 3.7e-10 39.8 0.0 5.6e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.18 CCC66765.1 - 7.7e-08 31.9 10.3 3.2e-05 23.3 1.1 3.0 2 1 1 3 3 3 2 6-phosphofructo-2-kinase PAP2 PF01569.21 CCC66767.1 - 1.8e-18 66.6 0.1 3.3e-18 65.8 0.1 1.4 1 0 0 1 1 1 1 PAP2 superfamily UPF0542 PF15086.6 CCC66767.1 - 0.0064 16.4 0.7 0.015 15.2 0.7 1.6 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 ACBP PF00887.19 CCC66768.1 - 2.9e-29 101.1 0.3 3.2e-29 101.0 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 CCC66768.1 - 0.01 16.2 0.1 0.51 10.8 0.0 2.0 1 1 1 2 2 2 0 FERM central domain ORMDL PF04061.14 CCC66769.1 - 2.6e-57 192.4 6.5 3.3e-57 192.1 6.5 1.1 1 0 0 1 1 1 1 ORMDL family OST3_OST6 PF04756.13 CCC66769.1 - 0.045 13.1 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Pkinase PF00069.25 CCC66770.1 - 1.5e-69 234.3 0.0 1.9e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC66770.1 - 4.7e-34 117.9 0.0 8.3e-34 117.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC66770.1 - 7.3e-05 22.2 0.0 0.00016 21.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCC66770.1 - 0.0013 18.1 0.2 0.0058 16.0 0.2 1.8 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CCC66770.1 - 0.0014 17.6 1.7 0.0048 15.9 1.7 1.7 1 1 0 1 1 1 1 Haspin like kinase domain DUF1160 PF06648.11 CCC66770.1 - 0.016 15.2 1.3 0.082 12.9 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) FTA2 PF13095.6 CCC66770.1 - 0.044 13.4 0.1 0.092 12.4 0.1 1.6 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF2533 PF10752.9 CCC66771.1 - 0.025 15.0 0.2 0.078 13.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) DUF1035 PF06281.12 CCC66771.1 - 4.5 7.3 6.3 3.6 7.7 1.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) DUF2439 PF10382.9 CCC66772.1 - 3.8e-23 81.6 1.6 7.3e-23 80.7 1.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) TAL_FSA PF00923.19 CCC66773.1 - 1.5e-93 313.3 2.7 1.8e-93 313.1 2.7 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase zf-C2H2 PF00096.26 CCC66774.1 - 1.2e-07 31.7 15.4 0.0086 16.5 0.3 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC66774.1 - 0.0015 19.2 15.4 0.39 11.7 0.7 4.2 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CCC66774.1 - 0.016 15.4 5.3 0.33 11.1 0.5 2.6 1 1 2 3 3 3 0 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 CCC66774.1 - 0.098 13.0 2.1 6.6 7.1 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf_ZIC PF18366.1 CCC66774.1 - 0.12 12.5 1.5 10 6.3 0.3 2.5 2 0 0 2 2 2 0 Zic proteins zinc finger domain zf-C2H2_2 PF12756.7 CCC66774.1 - 0.26 11.7 5.2 0.79 10.1 0.5 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.25 CCC66776.1 - 2.4e-48 164.8 0.0 3.1e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC66776.1 - 6.7e-27 94.4 0.0 9.5e-27 93.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC66776.1 - 1.9e-06 27.5 0.0 2e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CCC66776.1 - 0.00024 21.1 0.0 0.33 10.8 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CCC66776.1 - 0.0093 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CCC66776.1 - 0.07 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase MMU163 PF17119.5 CCC66777.1 - 1.3e-19 70.4 0.0 1.8e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial protein up-regulated during meiosis DUF2096 PF09869.9 CCC66777.1 - 0.088 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Bromodomain PF00439.25 CCC66778.1 - 2e-27 95.1 3.6 1.2e-12 47.7 0.7 3.0 2 0 0 2 2 2 2 Bromodomain BAH PF01426.18 CCC66778.1 - 1.2e-25 89.7 0.1 2.9e-25 88.5 0.1 1.7 1 0 0 1 1 1 1 BAH domain PBP1_TM PF14812.6 CCC66778.1 - 1.5 9.3 14.0 2 8.8 4.6 3.0 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Folliculin PF11704.8 CCC66779.1 - 6.1e-47 159.9 0.0 8.9e-47 159.4 0.0 1.3 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport DUF2321 PF10083.9 CCC66779.1 - 0.00019 21.1 0.0 0.00032 20.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2321) DUF3181 PF11378.8 CCC66779.1 - 0.16 12.3 0.1 0.33 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) EF-hand_7 PF13499.6 CCC66780.1 - 3.5e-10 40.2 3.6 1.5e-06 28.5 0.1 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CCC66780.1 - 2.1e-08 33.1 0.1 0.22 11.2 0.0 4.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 CCC66780.1 - 3.3e-07 29.7 2.5 0.012 15.5 0.1 4.3 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 CCC66780.1 - 3.8e-05 23.4 0.5 1.2 9.0 0.1 4.0 3 1 1 4 4 4 2 EF-hand domain pair PLU-1 PF08429.11 CCC66780.1 - 0.028 13.6 0.3 0.084 12.0 0.0 1.9 2 0 0 2 2 2 0 PLU-1-like protein EF-hand_5 PF13202.6 CCC66780.1 - 0.1 12.1 2.3 12 5.6 0.0 3.8 4 0 0 4 4 4 0 EF hand PEHE PF15275.6 CCC66780.1 - 1.6 9.4 7.0 4.7 7.9 6.8 2.0 1 1 0 1 1 1 0 PEHE domain Septin PF00735.18 CCC66781.1 - 1.6e-77 260.5 3.2 2.5e-77 259.9 3.2 1.3 1 0 0 1 1 1 1 Septin RsgA_GTPase PF03193.16 CCC66781.1 - 1.1e-06 28.7 2.2 5.6e-06 26.4 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CCC66781.1 - 5.4e-05 23.3 0.1 0.00013 22.0 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase IIGP PF05049.13 CCC66781.1 - 0.00086 18.5 0.9 0.0024 17.0 0.0 2.1 2 1 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Sigma54_activat PF00158.26 CCC66781.1 - 0.0038 17.0 0.1 0.031 14.0 0.0 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain ABC_tran PF00005.27 CCC66781.1 - 0.012 16.1 2.2 0.017 15.6 0.3 2.4 3 1 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 CCC66781.1 - 0.036 13.8 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 CCC66781.1 - 0.036 13.4 0.1 0.073 12.4 0.1 1.5 1 0 0 1 1 1 0 AIG1 family AAA_16 PF13191.6 CCC66781.1 - 0.057 13.8 0.0 0.12 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 CCC66781.1 - 0.066 12.9 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 CCC66781.1 - 0.08 13.2 0.1 0.19 11.9 0.1 1.7 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 CCC66781.1 - 0.086 13.2 0.3 0.41 11.0 0.0 2.3 3 0 0 3 3 3 0 RNA helicase Dynamin_N PF00350.23 CCC66781.1 - 0.089 12.8 1.8 0.12 12.5 0.2 2.0 2 0 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 CCC66781.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family MeaB PF03308.16 CCC66781.1 - 0.2 10.6 0.1 2.5 7.0 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FA_hydroxylase PF04116.13 CCC66782.1 - 3.5e-26 92.1 20.5 3.5e-26 92.1 20.5 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GATase_5 PF13507.6 CCC66783.1 - 1.6e-103 345.3 0.0 2.3e-103 344.8 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 CCC66783.1 - 1e-41 142.7 0.1 6.7e-29 101.0 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 CCC66783.1 - 4.8e-26 91.0 0.0 1e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 CCC66783.1 - 7.2e-22 77.7 0.0 1.7e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain DUF2462 PF09495.10 CCC66784.1 - 3.6e-15 56.5 11.1 3.6e-15 56.5 11.1 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) 60KD_IMP PF02096.20 CCC66785.1 - 1.4e-10 41.3 6.2 3e-10 40.2 0.5 2.2 1 1 1 2 2 2 2 60Kd inner membrane protein Spt4 PF06093.13 CCC66786.1 - 5.2e-29 100.2 0.2 6.1e-29 100.0 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-TFIIB PF13453.6 CCC66786.1 - 0.065 12.6 0.9 0.12 11.8 0.9 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger TackOD1 PF18551.1 CCC66786.1 - 0.11 12.1 1.0 0.15 11.7 1.0 1.1 1 0 0 1 1 1 0 Thaumarchaeal output domain 1 MFS_1 PF07690.16 CCC66787.1 - 1.5e-16 60.3 17.9 1.5e-16 60.3 17.9 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily 7TMR-DISM_7TM PF07695.11 CCC66787.1 - 0.003 17.5 8.7 0.003 17.5 8.7 3.2 2 2 1 3 3 3 1 7TM diverse intracellular signalling Ribosomal_S8 PF00410.19 CCC66788.1 - 8.6e-24 83.9 0.1 1.2e-23 83.4 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 zf-C2H2 PF00096.26 CCC66789.1 - 0.00028 21.2 13.2 0.028 14.9 4.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC66789.1 - 0.0022 18.3 5.7 0.0022 18.3 5.7 3.3 3 0 0 3 3 3 1 Zinc-finger double domain SR-25 PF10500.9 CCC66789.1 - 0.0035 17.0 4.0 0.0066 16.1 4.0 1.5 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CCC66789.1 - 0.0041 17.4 3.6 0.0041 17.4 3.6 2.5 2 0 0 2 2 2 1 Early growth response N-terminal domain zf-C2H2_4 PF13894.6 CCC66789.1 - 0.042 14.7 15.2 0.53 11.3 1.6 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger CDK2AP PF09806.9 CCC66789.1 - 0.27 11.3 4.4 0.97 9.5 4.4 1.8 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Arrestin_C PF02752.22 CCC66790.1 - 1.2e-19 71.1 0.3 5.1e-19 69.0 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCC66790.1 - 6.4e-09 36.0 0.0 1.7e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain CNH PF00780.22 CCC66791.1 - 3.5e-78 263.0 0.4 3.5e-78 263.0 0.4 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.6 CCC66791.1 - 4.5e-40 136.9 0.0 4.5e-40 136.9 0.0 3.5 5 0 0 5 5 5 1 Pleckstrin homology domain RhoGEF PF00621.20 CCC66791.1 - 3.7e-30 105.5 0.0 3.7e-30 105.5 0.0 2.9 3 0 0 3 3 3 1 RhoGEF domain DEP PF00610.21 CCC66791.1 - 6.4e-14 51.8 0.0 1.6e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ELO PF01151.18 CCC66792.1 - 6.6e-61 206.0 24.9 8.4e-61 205.7 24.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Methyltransf_34 PF11312.8 CCC66792.1 - 0.081 12.1 1.1 0.12 11.5 1.1 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase zf-BED PF02892.15 CCC66793.1 - 1.4e-06 28.2 0.1 3.2e-06 27.1 0.1 1.6 1 0 0 1 1 1 1 BED zinc finger zf-ACC PF17848.1 CCC66793.1 - 0.034 14.2 0.2 0.075 13.1 0.2 1.6 1 0 0 1 1 1 0 Acetyl-coA carboxylase zinc finger domain zf-C2H2_4 PF13894.6 CCC66794.1 - 3.9e-07 30.4 18.1 0.00042 20.9 0.7 4.8 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCC66794.1 - 0.00014 21.8 8.6 0.00034 20.5 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCC66794.1 - 0.00032 21.0 21.2 0.00048 20.4 1.4 4.9 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CCC66794.1 - 0.0016 18.6 4.2 0.063 13.6 0.0 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.12 CCC66794.1 - 0.033 14.5 5.6 0.04 14.2 2.0 2.8 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CCC66794.1 - 0.048 14.1 2.2 0.048 14.1 2.2 4.6 4 1 1 5 5 5 0 Zinc-finger double domain HtrL_YibB PF09612.10 CCC66794.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (HtrL_YibB) Tox-GHH PF15636.6 CCC66794.1 - 0.23 11.4 1.1 0.47 10.5 1.1 1.5 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin KRE9 PF05390.11 CCC66795.1 - 1.9e-49 166.6 10.2 1.9e-49 166.6 10.2 2.2 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CCC66795.1 - 1.2e-15 58.0 2.3 1.2e-15 58.0 2.3 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF3314 PF11771.8 CCC66795.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) La PF05383.17 CCC66796.1 - 8.9e-22 76.9 0.9 2.4e-21 75.5 0.1 2.1 2 0 0 2 2 2 1 La domain RRM_1 PF00076.22 CCC66796.1 - 3.2e-06 26.9 0.3 9.8e-06 25.3 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3662 PF12401.8 CCC66796.1 - 0.0098 16.3 0.1 0.14 12.5 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2662) BRAP2 PF07576.12 CCC66796.1 - 0.014 15.6 0.1 0.026 14.8 0.1 1.4 1 0 0 1 1 1 0 BRCA1-associated protein 2 Acyltransferase PF01553.21 CCC66797.1 - 3.7e-33 114.0 0.0 5e-33 113.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase VP4_2 PF08935.10 CCC66798.1 - 0.024 15.2 1.1 0.024 15.2 1.1 1.8 2 1 0 2 2 2 0 Viral protein VP4 subunit MFS_1 PF07690.16 CCC66799.1 - 5.9e-17 61.6 16.0 6.3e-17 61.5 15.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1774 PF08611.10 CCC66799.1 - 0.31 11.4 4.5 11 6.5 0.3 3.3 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) FA_hydroxylase PF04116.13 CCC66800.1 - 3.4e-26 92.2 21.2 3.4e-26 92.2 21.2 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NTP_transferase PF00483.23 CCC66801.1 - 1.9e-53 181.6 0.0 2.4e-53 181.3 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CCC66801.1 - 3.4e-14 51.9 8.7 9.8e-09 34.6 1.7 3.9 2 2 2 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CCC66801.1 - 5.1e-10 39.9 0.0 7e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CCC66801.1 - 0.00091 18.9 2.7 0.053 13.3 0.4 3.2 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CCC66801.1 - 0.011 14.7 0.1 0.11 11.4 0.1 2.0 2 0 0 2 2 2 0 L-fucokinase DUF4954 PF16314.5 CCC66801.1 - 0.026 12.7 0.3 0.038 12.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) CTP_transf_3 PF02348.19 CCC66801.1 - 0.091 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Ank_4 PF13637.6 CCC66802.1 - 2.8e-12 46.9 0.1 8.1e-05 23.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCC66802.1 - 5.6e-12 46.1 0.1 7e-05 23.3 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCC66802.1 - 1.9e-10 40.8 0.5 0.00012 22.3 0.3 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCC66802.1 - 3.6e-08 33.0 0.2 0.05 14.2 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.13 CCC66802.1 - 1.9e-07 30.9 0.2 1.3e-06 28.2 0.2 2.4 1 1 0 1 1 1 1 KilA-N domain Ank PF00023.30 CCC66802.1 - 3.5e-07 30.4 0.3 0.0024 18.2 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Uso1_p115_head PF04869.14 CCC66803.1 - 4.8e-101 338.0 7.6 4.8e-101 338.0 7.6 2.7 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 CCC66803.1 - 5e-15 56.0 39.3 5e-15 56.0 39.3 16.3 2 1 13 15 15 15 1 Uso1 / p115 like vesicle tethering protein, C terminal region Fez1 PF06818.15 CCC66803.1 - 0.0041 17.6 258.9 0.2 12.1 17.3 10.6 1 1 8 9 9 9 7 Fez1 Spc7 PF08317.11 CCC66803.1 - 0.21 10.5 294.4 0.37 9.6 31.0 12.2 1 1 11 12 12 12 0 Spc7 kinetochore protein Filament PF00038.21 CCC66803.1 - 2.4 7.6 253.3 0.11 12.0 51.3 8.6 1 1 6 7 7 7 0 Intermediate filament protein Rad52_Rad22 PF04098.15 CCC66804.1 - 1.9e-45 154.5 0.1 2.3e-45 154.2 0.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein FlgT_N PF16548.5 CCC66804.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Flagellar assembly protein T, N-terminal domain Ribosomal_S14 PF00253.21 CCC66805.1 - 4.1e-15 55.3 3.0 4.6e-15 55.1 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.12 CCC66805.1 - 0.038 14.3 2.4 1 9.7 0.3 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase CTNNBL PF08216.11 CCC66806.1 - 0.059 13.5 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 Catenin-beta-like, Arm-motif containing nuclear LON_substr_bdg PF02190.16 CCC66806.1 - 0.44 10.4 2.9 0.32 10.8 0.5 2.0 2 0 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain UQ_con PF00179.26 CCC66807.1 - 8e-45 151.9 0.2 9.1e-45 151.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCC66807.1 - 2.4e-05 24.1 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CCC66807.1 - 0.17 12.1 4.0 0.62 10.4 4.0 1.9 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.12 CCC66808.1 - 4e-50 170.9 14.1 5.4e-50 170.4 14.1 1.2 1 0 0 1 1 1 1 Pex19 protein family CHAD PF05235.14 CCC66808.1 - 0.0042 17.1 1.2 0.01 15.8 1.2 1.6 1 1 0 1 1 1 1 CHAD domain FtsK_SpoIIIE PF01580.18 CCC66808.1 - 0.096 12.0 0.2 0.19 11.0 0.2 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsbRD_N PF14361.6 CCC66808.1 - 1.4 9.7 4.0 21 5.9 0.2 3.0 1 1 1 3 3 3 0 RsbT co-antagonist protein rsbRD N-terminal domain Iso_dh PF00180.20 CCC66809.1 - 8.4e-68 229.0 0.0 9.9e-68 228.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Rxt3 PF08642.10 CCC66810.1 - 1.6e-23 83.8 1.2 9.6e-21 74.9 0.0 3.1 2 1 0 2 2 2 1 Histone deacetylation protein Rxt3 Ribosomal_L31e PF01198.19 CCC66811.1 - 3.9e-41 139.2 1.2 4.7e-41 138.9 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MFS_1 PF07690.16 CCC66812.1 - 9.3e-29 100.4 61.7 1.6e-28 99.7 54.6 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC66812.1 - 2.6e-07 29.9 4.7 2.6e-07 29.9 4.7 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter BRE1 PF08647.11 CCC66813.1 - 1.7e-24 85.7 13.3 1.7e-24 85.7 13.3 7.1 4 2 2 6 6 4 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.6 CCC66813.1 - 4.5e-08 32.8 11.2 8.3e-08 32.0 11.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCC66813.1 - 1.9e-06 27.6 9.8 3.5e-06 26.8 9.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CCC66813.1 - 6.1e-06 26.0 12.6 6.1e-06 26.0 12.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCC66813.1 - 1e-05 25.4 13.2 2e-05 24.5 13.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CCC66813.1 - 0.00018 21.3 14.2 0.00018 21.3 14.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCC66813.1 - 0.00064 20.0 12.2 0.0012 19.1 12.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CCC66813.1 - 0.0018 18.3 9.1 0.0048 16.9 9.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger DUF2379 PF09543.10 CCC66813.1 - 0.13 12.4 2.7 0.12 12.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) zf-RING_6 PF14835.6 CCC66813.1 - 0.26 11.2 3.8 0.53 10.2 3.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C2H2 PF00096.26 CCC66813.1 - 0.54 10.8 0.1 0.54 10.8 0.1 2.6 3 0 0 3 3 2 0 Zinc finger, C2H2 type zf-RING_4 PF14570.6 CCC66813.1 - 2.2 8.1 10.9 5.8 6.8 10.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.21 CCC66813.1 - 4 7.6 13.3 64 3.8 13.3 2.5 1 1 0 1 1 1 0 FYVE zinc finger DUF1765 PF08578.10 CCC66814.1 - 8.7e-20 71.4 22.5 1.1e-19 71.2 9.0 4.2 4 1 0 4 4 4 2 Protein of unknown function (DUF1765) KIP1 PF07765.12 CCC66814.1 - 0.062 13.4 0.8 10 6.3 0.1 3.3 2 0 0 2 2 2 0 KIP1-like protein zf-C2H2_4 PF13894.6 CCC66815.1 - 0.00031 21.3 14.3 0.052 14.4 0.6 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCC66815.1 - 0.00034 20.9 17.3 0.067 13.7 0.9 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 CCC66815.1 - 0.0011 19.1 13.0 0.0043 17.2 0.4 3.5 3 0 0 3 3 3 2 Aberrant zinc-finger zf-C2H2_jaz PF12171.8 CCC66815.1 - 0.0028 17.9 0.6 2.8 8.3 0.1 3.0 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CCC66815.1 - 0.06 13.8 15.1 0.15 12.5 1.0 3.5 3 0 0 3 3 3 0 Zinc-finger double domain Asparaginase_II PF06089.12 CCC66815.1 - 0.15 11.1 1.0 0.23 10.4 1.0 1.2 1 0 0 1 1 1 0 L-asparaginase II MCM_OB PF17207.3 CCC66815.1 - 2 8.2 6.4 0.7 9.7 0.2 2.6 2 1 0 2 2 2 0 MCM OB domain Bap31 PF05529.12 CCC66816.1 - 9e-42 142.1 0.6 1.4e-41 141.6 0.6 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Wzy_C PF04932.15 CCC66816.1 - 0.022 14.4 1.0 0.029 14.0 0.8 1.3 1 1 0 1 1 1 0 O-Antigen ligase DUF724 PF05266.14 CCC66816.1 - 0.14 12.0 6.5 0.23 11.3 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) RIC3 PF15361.6 CCC66816.1 - 0.45 10.9 3.5 0.79 10.1 3.5 1.4 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF5595 PF18077.1 CCC66816.1 - 1.8 8.7 6.9 1 9.5 4.0 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) Vps39_1 PF10366.9 CCC66819.1 - 3.8e-26 91.5 0.5 1.6e-25 89.5 0.5 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.9 CCC66819.1 - 1.2e-13 51.4 0.0 3.4e-13 50.0 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 YmzC PF14157.6 CCC66819.1 - 0.11 12.6 3.8 2.4 8.3 0.2 3.3 3 0 0 3 3 3 0 YmzC-like protein Pribosyltran_N PF13793.6 CCC66820.1 - 4.5e-40 136.2 0.0 1.2e-39 134.9 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CCC66820.1 - 3.3e-39 134.8 0.8 4e-31 108.5 0.1 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CCC66820.1 - 1.2e-07 31.4 0.1 0.00049 19.7 0.0 2.2 2 0 0 2 2 2 2 Phosphoribosyl transferase domain UPRTase PF14681.6 CCC66820.1 - 0.14 11.6 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Voldacs PF03517.13 CCC66821.1 - 9.7e-20 71.1 0.1 1.7e-19 70.3 0.1 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Orn_Arg_deC_N PF02784.16 CCC66822.1 - 1.2e-79 267.2 0.0 1.8e-79 266.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 CCC66822.1 - 4.3e-18 65.4 0.0 5.8e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain GATA PF00320.27 CCC66823.1 - 1.9e-08 33.8 6.6 4.8e-08 32.5 6.6 1.8 1 0 0 1 1 1 1 GATA zinc finger Mtr2 PF10429.9 CCC66824.1 - 8e-73 243.8 0.1 9.3e-73 243.6 0.1 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 SUR7 PF06687.12 CCC66825.1 - 3.9e-14 52.8 22.9 4e-13 49.5 22.9 2.4 1 1 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 CCC66825.1 - 0.0036 17.3 5.9 0.0036 17.3 5.9 3.0 3 0 0 3 3 3 2 Ca2+ regulator and membrane fusion protein Fig1 nsp7 PF08716.10 CCC66825.1 - 0.01 16.5 0.7 0.5 11.0 0.0 3.2 2 1 1 3 3 3 0 nsp7 replicase DASH_Dad4 PF08650.10 CCC66825.1 - 0.02 14.9 4.1 0.05 13.6 0.2 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad4 DUF3516 PF12029.8 CCC66825.1 - 0.074 12.1 0.3 0.16 11.0 0.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) TERF2_RBM PF16772.5 CCC66825.1 - 0.11 11.9 0.1 0.34 10.4 0.1 1.8 1 0 0 1 1 1 0 Telomeric repeat-binding factor 2 Rap1-binding motif ABC_membrane_2 PF06472.15 CCC66826.1 - 3.6e-73 246.3 8.5 4.9e-73 245.8 8.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CCC66826.1 - 2.3e-18 67.0 0.0 1.6e-16 61.0 0.0 2.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CCC66826.1 - 2.7e-05 24.2 0.5 0.00015 21.7 0.1 2.6 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CCC66826.1 - 0.00037 21.0 3.2 0.00037 21.0 3.2 2.8 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CCC66826.1 - 0.012 15.6 0.0 0.036 14.0 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 CCC66826.1 - 0.022 14.5 0.0 0.057 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 CCC66826.1 - 0.03 14.6 0.0 0.15 12.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCC66826.1 - 0.083 12.4 0.2 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Mo25 PF08569.11 CCC66827.1 - 4e-108 361.7 16.8 4.8e-108 361.4 16.8 1.1 1 0 0 1 1 1 1 Mo25-like DUF3310 PF11753.8 CCC66827.1 - 2.3 8.5 4.0 2.4 8.4 0.2 2.9 3 0 0 3 3 3 0 Protein of unknwon function (DUF3310) DsbG_N PF18257.1 CCC66828.1 - 0.04 14.0 0.1 0.18 12.0 0.0 2.2 2 1 0 2 2 2 0 Disulfide isomerase DsbG N-terminal EF-hand_1 PF00036.32 CCC66829.1 - 2.6e-24 82.9 13.0 1.3e-05 24.4 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CCC66829.1 - 1.6e-20 73.3 6.5 8.4e-12 45.4 1.0 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCC66829.1 - 2.4e-19 67.5 6.6 0.00024 20.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CCC66829.1 - 4.6e-16 57.5 13.4 0.00071 19.0 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 CCC66829.1 - 3.1e-10 39.7 13.5 0.0065 16.3 0.3 4.4 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.7 CCC66829.1 - 8e-07 29.0 9.6 0.0049 16.8 0.2 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 CCC66829.1 - 4.5e-06 26.9 0.1 0.14 12.5 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 CCC66829.1 - 0.0028 17.9 0.1 3.8 7.9 0.0 2.9 2 1 1 3 3 3 2 EF-hand domain Diphthamide_syn PF01866.17 CCC66830.1 - 4.7e-67 226.6 0.0 8.9e-67 225.7 0.0 1.4 1 1 0 1 1 1 1 Putative diphthamide synthesis protein LRR_4 PF12799.7 CCC66831.1 - 4.7e-31 106.3 42.7 9.2e-09 35.5 2.7 7.4 3 2 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCC66831.1 - 1.1e-22 79.6 44.0 4.2e-10 39.2 1.9 6.4 3 1 4 7 7 7 6 Leucine rich repeat LRR_9 PF14580.6 CCC66831.1 - 7e-16 58.2 22.7 1.3e-08 34.5 2.9 4.5 1 1 4 5 5 5 4 Leucine-rich repeat LRR_1 PF00560.33 CCC66831.1 - 0.0018 18.6 26.5 1.4 9.8 0.3 9.3 9 3 0 9 9 9 2 Leucine Rich Repeat 2H-phosphodiest PF08975.10 CCC66831.1 - 0.1 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1868) UB2H PF14814.6 CCC66831.1 - 0.35 10.9 2.0 57 3.8 0.0 4.0 2 2 4 6 6 6 0 Bifunctional transglycosylase second domain CPSase_L_D3 PF02787.19 CCC66831.1 - 0.51 10.7 2.6 8.5 6.7 2.4 2.5 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain LRR_6 PF13516.6 CCC66831.1 - 7.7 6.8 27.5 0.24 11.6 0.4 6.5 8 0 0 8 8 8 0 Leucine Rich repeat tRNA-synt_2b PF00587.25 CCC66832.1 - 2.6e-43 148.1 0.0 3.6e-43 147.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CCC66832.1 - 3.2e-13 49.7 0.1 5.5e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 Anticodon binding domain CHCH PF06747.13 CCC66833.1 - 0.0014 18.7 5.2 0.0028 17.7 5.2 1.5 1 0 0 1 1 1 1 CHCH domain Synaptobrevin PF00957.21 CCC66834.1 - 2.2e-15 56.2 1.2 3.7e-15 55.5 1.2 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 CCC66834.1 - 2e-11 43.8 0.0 3.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain DUF3461 PF11944.8 CCC66834.1 - 0.14 12.3 3.5 0.13 12.4 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3461) FMN_dh PF01070.18 CCC66835.1 - 2.2e-117 392.0 0.0 2.7e-117 391.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CCC66835.1 - 1.1e-22 80.0 0.0 2.1e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CCC66835.1 - 1.2e-08 34.5 0.0 4.5e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CCC66835.1 - 0.00053 19.1 0.3 0.017 14.1 0.0 3.0 3 1 1 4 4 4 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.15 CCC66835.1 - 0.0035 16.8 0.0 0.0095 15.4 0.0 1.7 2 0 0 2 2 2 1 Nitronate monooxygenase ThiG PF05690.14 CCC66835.1 - 0.051 12.9 0.0 1.7 7.9 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.21 CCC66835.1 - 0.06 12.8 0.2 11 5.5 0.0 2.8 3 0 0 3 3 3 0 Histidine biosynthesis protein Tubulin_3 PF14881.6 CCC66835.1 - 0.074 12.7 0.1 0.35 10.5 0.0 2.1 1 1 1 2 2 2 0 Tubulin domain FMN_dh PF01070.18 CCC66836.1 - 3.3e-120 401.3 0.0 4.3e-120 400.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.28 CCC66836.1 - 8.1e-23 80.4 0.0 1.6e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.17 CCC66836.1 - 8.6e-09 35.0 0.1 7.6e-08 31.9 0.0 1.9 1 1 0 2 2 2 1 Conserved region in glutamate synthase NMO PF03060.15 CCC66836.1 - 1.2e-05 24.9 0.0 2.8e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CCC66836.1 - 0.0007 18.7 1.3 0.01 14.9 0.0 2.7 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 CCC66836.1 - 0.021 14.3 0.1 9.8 5.6 0.0 2.7 3 0 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.14 CCC66836.1 - 0.028 13.7 0.1 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG Glyco_hydro_36 PF17167.4 CCC66836.1 - 0.048 12.3 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain SPC25 PF06703.11 CCC66837.1 - 2.9e-37 127.9 4.3 3.3e-37 127.8 4.3 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Lactate_perm PF02652.14 CCC66837.1 - 0.045 12.5 0.0 0.049 12.4 0.0 1.1 1 0 0 1 1 1 0 L-lactate permease DUF1899 PF08953.11 CCC66838.1 - 1.2e-25 89.1 0.1 2.6e-25 88.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.32 CCC66838.1 - 1.6e-15 57.2 6.6 0.00055 20.7 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC66838.1 - 5.5e-06 26.6 0.1 0.00066 19.9 0.1 3.5 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCC66838.1 - 6e-05 23.0 0.0 0.013 15.4 0.0 3.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CCC66838.1 - 0.0003 19.6 0.3 0.014 14.1 0.1 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Nbas_N PF15492.6 CCC66838.1 - 0.0006 19.2 0.0 0.0026 17.1 0.0 2.0 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal IMPDH PF00478.25 CCC66839.1 - 2.1e-130 434.8 1.8 2.5e-130 434.5 1.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 CCC66839.1 - 1.2e-13 51.3 0.0 2.1e-05 24.9 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.18 CCC66839.1 - 6.8e-06 25.3 3.7 1.7e-05 24.0 3.6 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 CCC66839.1 - 2e-05 24.2 5.4 0.015 14.7 3.5 2.6 2 1 1 3 3 3 2 Nitronate monooxygenase His_biosynth PF00977.21 CCC66839.1 - 0.00047 19.7 1.4 0.0053 16.2 1.4 2.3 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 CCC66839.1 - 0.0087 15.4 0.7 0.0087 15.4 0.7 1.5 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 CCC66839.1 - 0.011 15.1 0.1 0.04 13.4 0.1 1.9 1 0 0 1 1 1 0 KDPG and KHG aldolase YpsA PF06908.11 CCC66839.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 YspA SLOG family Metallophos PF00149.28 CCC66840.1 - 6e-36 124.9 0.1 1e-35 124.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase cNMP_binding PF00027.29 CCC66843.1 - 1.1e-26 92.8 1.1 3.8e-13 49.3 0.1 6.2 5 1 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.22 CCC66843.1 - 3.8e-16 59.9 6.3 1.3e-14 54.9 4.0 3.3 2 1 0 2 2 2 1 Patatin-like phospholipase CENP-B_dimeris PF09026.10 CCC66843.1 - 1 9.8 8.3 3.7 8.0 8.3 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain OGG_N PF07934.12 CCC66844.1 - 3.2e-21 75.7 1.0 4.2e-21 75.3 0.2 1.6 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 CCC66844.1 - 7.1e-21 74.7 0.0 1.2e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PIF1 PF05970.14 CCC66845.1 - 2e-74 251.0 1.2 1.2e-71 241.8 1.2 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CCC66845.1 - 1e-17 64.5 0.0 2.3e-17 63.3 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CCC66845.1 - 3.9e-09 37.0 0.0 8.8e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCC66845.1 - 2e-05 24.9 0.0 7.2e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCC66845.1 - 0.0012 18.5 0.0 0.0035 16.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 CCC66845.1 - 0.0022 18.4 0.1 0.011 16.1 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CCC66845.1 - 0.0069 16.8 0.1 0.017 15.5 0.1 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CCC66845.1 - 0.008 15.9 0.5 2.1 8.0 0.3 2.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CCC66845.1 - 0.0094 15.8 0.0 0.027 14.3 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain T2SSE PF00437.20 CCC66845.1 - 0.021 13.9 0.2 0.039 13.0 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 CCC66845.1 - 0.024 14.0 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.12 CCC66845.1 - 0.041 13.8 0.0 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain DUF5053 PF16476.5 CCC66845.1 - 0.1 12.3 0.1 0.35 10.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) RRM_1 PF00076.22 CCC66846.1 - 1.6e-28 98.3 2.4 5.2e-14 51.8 0.1 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CCC66846.1 - 6.2e-08 32.5 0.1 0.015 15.3 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.13 CCC66846.1 - 0.0006 19.7 0.3 0.73 9.8 0.1 2.8 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Trypan_PARP PF05887.11 CCC66846.1 - 0.006 16.6 10.1 0.014 15.4 10.1 1.5 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) AF-4 PF05110.13 CCC66846.1 - 0.037 12.1 21.3 0.059 11.5 21.3 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein NESP55 PF06390.12 CCC66846.1 - 0.071 12.7 13.5 0.16 11.6 13.5 1.5 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) RRM_7 PF16367.5 CCC66846.1 - 0.093 12.9 0.0 1.1 9.4 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif RRM_occluded PF16842.5 CCC66846.1 - 0.099 12.5 0.1 5 7.1 0.1 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif SDA1 PF05285.12 CCC66846.1 - 0.12 11.7 12.5 0.23 10.8 12.5 1.4 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 CCC66846.1 - 0.14 11.5 17.9 0.24 10.7 17.9 1.3 1 0 0 1 1 1 0 BUD22 PNISR PF15996.5 CCC66846.1 - 3.6 7.8 13.1 3.9 7.7 10.8 2.0 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR Nop14 PF04147.12 CCC66846.1 - 9.7 4.3 18.1 15 3.7 18.1 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_2 PF07724.14 CCC66847.1 - 1.9e-46 158.3 0.0 2e-45 155.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CCC66847.1 - 5e-28 97.1 0.4 5e-28 97.1 0.4 3.3 1 1 0 2 2 2 1 AAA lid domain AAA PF00004.29 CCC66847.1 - 3.8e-23 82.4 0.1 1.4e-13 51.4 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CCC66847.1 - 6.2e-23 80.7 0.5 2.5e-22 78.7 0.5 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CCC66847.1 - 9.5e-16 58.0 0.0 2.2e-08 34.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 CCC66847.1 - 1.7e-12 47.2 10.4 1.2e-08 34.9 0.8 4.4 4 0 0 4 4 3 2 Clp amino terminal domain, pathogenicity island component Sigma54_activat PF00158.26 CCC66847.1 - 2.3e-12 46.9 0.2 1.2e-08 34.8 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 CCC66847.1 - 2.6e-08 34.5 5.8 0.00019 21.9 0.0 4.5 4 1 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.6 CCC66847.1 - 5.7e-07 29.9 0.6 0.058 13.7 0.1 4.1 2 2 0 2 2 2 2 AAA domain TniB PF05621.11 CCC66847.1 - 2.5e-05 23.8 0.0 0.0082 15.6 0.0 3.9 2 1 1 3 3 3 1 Bacterial TniB protein TIP49 PF06068.13 CCC66847.1 - 0.00011 21.6 2.8 0.53 9.4 0.0 3.6 4 0 0 4 4 4 2 TIP49 P-loop domain Mg_chelatase PF01078.21 CCC66847.1 - 0.00026 20.4 0.0 1.2 8.4 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CCC66847.1 - 0.00036 20.1 0.0 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 CCC66847.1 - 0.00056 19.7 0.0 0.063 13.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain Torsin PF06309.11 CCC66847.1 - 0.0013 18.8 0.0 0.0069 16.5 0.0 2.2 2 0 0 2 2 1 1 Torsin Zeta_toxin PF06414.12 CCC66847.1 - 0.0025 17.1 0.4 0.42 9.9 0.0 3.4 3 1 1 4 4 4 1 Zeta toxin NACHT PF05729.12 CCC66847.1 - 0.0036 17.2 0.0 4.6 7.1 0.0 2.7 2 0 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 CCC66847.1 - 0.004 17.3 0.0 0.49 10.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.13 CCC66847.1 - 0.0051 16.0 0.0 0.21 10.7 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CCC66847.1 - 0.0057 16.4 0.0 0.52 10.0 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.27 CCC66847.1 - 0.0096 16.4 2.7 1.7 9.1 0.0 3.6 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 CCC66847.1 - 0.016 15.1 0.0 3.2 7.6 0.0 2.9 2 1 0 2 2 2 0 RsgA GTPase Roc PF08477.13 CCC66847.1 - 0.019 15.2 0.0 6.5 7.0 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CCC66847.1 - 0.023 14.4 0.0 3.8 7.3 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_3 PF07726.11 CCC66847.1 - 0.031 14.1 0.0 0.63 9.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CCC66847.1 - 0.044 14.3 2.1 7.3 7.2 0.0 3.5 4 0 0 4 4 2 0 AAA domain Viral_helicase1 PF01443.18 CCC66847.1 - 0.047 13.4 0.0 5.1 6.8 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase PEPCK_ATP PF01293.20 CCC66847.1 - 0.047 12.4 0.0 0.079 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase RNA_helicase PF00910.22 CCC66847.1 - 0.055 13.9 0.1 8.6 6.8 0.0 2.9 3 0 0 3 3 2 0 RNA helicase ATPase_2 PF01637.18 CCC66847.1 - 0.057 13.3 8.7 5.3 6.9 0.1 4.5 3 2 2 5 5 5 0 ATPase domain predominantly from Archaea NTPase_1 PF03266.15 CCC66847.1 - 0.093 12.6 0.0 6.7 6.6 0.0 3.0 3 0 0 3 3 2 0 NTPase TsaE PF02367.17 CCC66847.1 - 0.099 12.7 0.0 7.6 6.6 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 CCC66847.1 - 0.13 12.6 0.3 5.1 7.4 0.1 3.3 2 2 0 2 2 2 0 AAA domain DUF5368 PF17336.2 CCC66847.1 - 0.21 11.8 0.0 0.42 10.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5368) Spc7 PF08317.11 CCC66847.1 - 0.23 10.3 18.7 0.4 9.5 18.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein PDCD7 PF16021.5 CCC66847.1 - 1.1 8.3 15.6 1.9 7.5 15.6 1.3 1 0 0 1 1 1 0 Programmed cell death protein 7 V_ATPase_I PF01496.19 CCC66847.1 - 2.1 6.2 10.6 3.3 5.5 10.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.9 CCC66847.1 - 7.4 6.9 13.5 9.4 6.6 2.1 3.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fe-S_biosyn PF01521.20 CCC66848.1 - 2.7e-18 66.2 0.0 8e-17 61.4 0.0 2.2 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis XRCC4 PF06632.12 CCC66848.1 - 0.00058 18.8 2.6 0.00095 18.1 2.6 1.3 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF3853 PF12964.7 CCC66848.1 - 0.12 12.6 0.0 0.4 10.9 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) Peptidase_M24 PF00557.24 CCC66849.1 - 3.7e-40 137.8 0.0 5.4e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 CCC66849.1 - 6.3e-38 130.4 0.2 1.4e-37 129.2 0.2 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 CCC66849.1 - 4.5e-21 74.7 1.0 1.5e-20 73.0 1.0 1.9 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CCC66849.1 - 3.7e-08 34.1 0.0 7.7e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain KH_1 PF00013.29 CCC66850.1 - 6.7e-08 32.2 0.0 0.016 15.0 0.0 4.7 5 0 0 5 5 5 2 KH domain TSP_NTD PF17804.1 CCC66850.1 - 0.00061 20.1 0.6 0.0016 18.7 0.6 1.7 1 0 0 1 1 1 1 Tail specific protease N-terminal domain AAA PF00004.29 CCC66852.1 - 1.9e-93 309.8 0.0 3.8e-47 160.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC66852.1 - 2.1e-21 75.4 0.1 2.6e-09 36.7 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CCC66852.1 - 1e-14 54.6 0.0 5.5e-07 29.5 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCC66852.1 - 1.8e-13 51.2 0.9 8.2e-05 23.0 0.0 4.2 3 2 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 CCC66852.1 - 3.7e-10 40.2 0.3 0.016 15.5 0.0 4.9 2 2 2 4 4 4 2 AAA domain AAA_33 PF13671.6 CCC66852.1 - 7.1e-10 39.2 0.0 0.00027 21.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CCC66852.1 - 1.3e-09 38.2 0.2 0.001 19.1 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CCC66852.1 - 2.1e-09 37.7 0.0 0.00087 19.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) Vps4_C PF09336.10 CCC66852.1 - 3e-09 36.7 0.2 0.00014 21.7 0.1 3.1 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain TIP49 PF06068.13 CCC66852.1 - 8.2e-09 35.1 0.0 0.00033 20.0 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 CCC66852.1 - 2.6e-08 34.5 0.0 0.00069 20.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 CCC66852.1 - 9.7e-08 32.1 0.0 0.03 14.4 0.0 3.2 3 0 0 3 3 2 2 AAA domain RNA_helicase PF00910.22 CCC66852.1 - 4e-07 30.4 0.0 0.031 14.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.27 CCC66852.1 - 4.2e-07 30.6 0.1 0.025 15.1 0.0 3.1 3 0 0 3 3 2 2 ABC transporter Zeta_toxin PF06414.12 CCC66852.1 - 1.8e-06 27.4 0.0 0.049 12.9 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_3 PF07726.11 CCC66852.1 - 2.7e-06 27.3 0.0 0.085 12.7 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CCC66852.1 - 3e-06 27.1 0.1 0.039 13.7 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.15 CCC66852.1 - 3.6e-06 27.0 0.0 0.013 15.4 0.0 2.6 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_28 PF13521.6 CCC66852.1 - 4.3e-06 27.1 0.0 0.056 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CCC66852.1 - 5e-06 26.1 0.3 0.062 12.7 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.6 CCC66852.1 - 1.9e-05 24.9 0.1 0.0013 18.9 0.0 2.9 3 0 0 3 3 2 1 Cytidylate kinase-like family AAA_17 PF13207.6 CCC66852.1 - 3.4e-05 24.3 0.1 0.14 12.6 0.1 3.6 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 CCC66852.1 - 7e-05 22.8 0.1 0.5 10.3 0.0 3.1 3 0 0 3 3 2 2 NACHT domain TsaE PF02367.17 CCC66852.1 - 0.0001 22.3 0.0 0.7 9.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 CCC66852.1 - 0.00019 21.6 0.0 0.27 11.3 0.0 3.0 3 0 0 3 3 2 1 Shikimate kinase AAA_7 PF12775.7 CCC66852.1 - 0.00019 21.0 0.0 0.46 10.0 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 CCC66852.1 - 0.00022 20.8 0.2 1.5 8.3 0.0 3.7 4 1 1 5 5 4 1 AAA domain Sigma54_activat PF00158.26 CCC66852.1 - 0.00024 20.9 0.0 0.25 11.0 0.0 3.1 2 1 1 3 3 3 1 Sigma-54 interaction domain AAA_11 PF13086.6 CCC66852.1 - 0.00025 20.9 2.8 0.65 9.7 0.0 3.4 3 0 0 3 3 3 2 AAA domain DUF815 PF05673.13 CCC66852.1 - 0.00027 20.2 0.1 0.1 11.8 0.0 2.9 3 0 0 3 3 2 1 Protein of unknown function (DUF815) Cytidylate_kin PF02224.18 CCC66852.1 - 0.00037 20.3 0.5 1 9.0 0.0 3.6 3 0 0 3 3 3 1 Cytidylate kinase Viral_helicase1 PF01443.18 CCC66852.1 - 0.00047 20.0 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.6 CCC66852.1 - 0.00077 19.2 0.0 0.89 9.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 CCC66852.1 - 0.001 18.3 0.0 1 8.5 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain Sigma54_activ_2 PF14532.6 CCC66852.1 - 0.0012 19.0 0.0 2.4 8.3 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 CCC66852.1 - 0.0012 18.8 0.0 1.8 8.4 0.0 3.1 2 1 1 3 3 3 1 ATPase domain predominantly from Archaea ATPase PF06745.13 CCC66852.1 - 0.0017 17.8 0.0 1.6 8.0 0.0 3.2 3 0 0 3 3 3 1 KaiC CPT PF07931.12 CCC66852.1 - 0.0017 18.2 0.0 0.038 13.8 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Parvo_NS1 PF01057.17 CCC66852.1 - 0.0025 17.0 0.0 2 7.5 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 SRPRB PF09439.10 CCC66852.1 - 0.0046 16.4 0.0 1.5 8.2 0.0 3.0 3 0 0 3 3 2 1 Signal recognition particle receptor beta subunit AAA_19 PF13245.6 CCC66852.1 - 0.01 16.2 0.0 2.8 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain FPRL1_inhibitor PF16104.5 CCC66852.1 - 0.015 15.4 0.3 0.046 13.9 0.3 1.8 1 0 0 1 1 1 0 Formyl peptide receptor-like 1 inhibitory protein PduV-EutP PF10662.9 CCC66852.1 - 0.016 14.9 0.0 8.1 6.2 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PhoH PF02562.16 CCC66852.1 - 0.02 14.3 0.1 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AFG1_ATPase PF03969.16 CCC66852.1 - 0.028 13.3 0.2 9.8 4.9 0.0 2.9 3 0 0 3 3 3 0 AFG1-like ATPase RRM_1 PF00076.22 CCC66852.1 - 0.03 14.1 0.1 0.53 10.1 0.0 2.8 3 0 0 3 3 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NTPase_1 PF03266.15 CCC66852.1 - 0.038 13.9 0.0 13 5.7 0.0 2.7 2 0 0 2 2 2 0 NTPase Hydin_ADK PF17213.3 CCC66852.1 - 0.054 13.8 3.5 0.79 10.0 0.0 3.5 4 0 0 4 4 4 0 Hydin Adenylate kinase-like domain RsgA_GTPase PF03193.16 CCC66852.1 - 0.078 12.9 0.0 0.98 9.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase TniB PF05621.11 CCC66852.1 - 0.1 12.0 0.0 20 4.5 0.0 2.8 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 CCC66852.1 - 0.11 12.1 0.1 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Guanylate_kin PF00625.21 CCC66852.1 - 0.12 12.0 0.4 13 5.4 0.0 3.9 3 1 1 4 4 4 0 Guanylate kinase MMR_HSR1 PF01926.23 CCC66852.1 - 0.13 12.4 0.4 3 7.9 0.1 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.6 CCC66852.1 - 0.15 11.8 0.0 17 5.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 CCC66852.1 - 0.22 12.0 7.1 1.1 9.8 0.0 4.0 4 0 0 4 4 4 0 AAA domain CLP1_P PF16575.5 CCC66853.1 - 9.2e-28 97.3 0.0 2.3e-27 96.0 0.0 1.7 1 1 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Dynamin_N PF00350.23 CCC66853.1 - 0.0023 18.0 0.0 0.02 14.9 0.1 2.3 2 1 0 2 2 2 1 Dynamin family G-alpha PF00503.20 CCC66853.1 - 0.0097 15.1 5.5 0.033 13.4 5.5 1.9 1 1 0 1 1 1 1 G-protein alpha subunit AAA_14 PF13173.6 CCC66853.1 - 0.018 15.1 0.1 0.1 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 CCC66853.1 - 0.031 14.4 0.0 0.068 13.3 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 CCC66853.1 - 0.078 13.5 0.2 1.7 9.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 CCC66853.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_18 PF13238.6 CCC66853.1 - 0.12 12.9 0.0 0.35 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain WSC PF01822.19 CCC66854.1 - 1.9e-07 31.1 12.9 1.9e-07 31.1 12.9 2.7 2 1 0 2 2 2 1 WSC domain Orf78 PF06024.12 CCC66854.1 - 0.012 15.9 0.1 0.012 15.9 0.1 2.3 2 1 0 2 2 2 0 Orf78 (ac78) FixQ PF05545.11 CCC66854.1 - 0.015 15.2 0.1 0.039 13.9 0.1 1.6 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Vpu PF00558.19 CCC66854.1 - 0.086 12.6 0.5 0.18 11.6 0.5 1.5 1 0 0 1 1 1 0 Vpu protein EphA2_TM PF14575.6 CCC66854.1 - 0.098 13.5 0.5 0.99 10.3 0.0 2.8 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Phage_holin_2_4 PF16082.5 CCC66854.1 - 0.15 11.8 0.0 0.39 10.5 0.0 1.7 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like CCSMST1 PF15013.6 CCC66854.1 - 0.51 10.5 3.9 0.7 10.1 0.0 2.7 2 0 0 2 2 2 0 CCSMST1 family YebO PF13974.6 CCC66854.1 - 1.3 9.2 2.9 3.9 7.6 2.9 1.8 1 0 0 1 1 1 0 YebO-like protein UPF0688 PF15772.5 CCC66854.1 - 7 6.8 19.5 18 5.5 19.5 1.7 1 0 0 1 1 1 0 UPF0688 family SHR-BD PF06650.12 CCC66855.1 - 4.3e-92 308.3 12.1 3e-88 295.7 1.8 3.5 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 CCC66855.1 - 4.4e-73 245.6 1.2 4.4e-73 245.6 1.2 6.9 5 2 3 8 8 8 2 Repeating coiled region of VPS13 VPS13_C PF16909.5 CCC66855.1 - 8.3e-71 237.4 6.0 1e-67 227.4 0.6 3.0 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 CCC66855.1 - 5.2e-66 222.8 6.2 1.1e-65 221.7 1.2 3.2 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 CCC66855.1 - 3.1e-35 120.8 0.9 2.5e-34 117.9 0.2 3.0 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 Fer2_3 PF13085.6 CCC66856.1 - 7.6e-32 109.6 0.0 1.4e-31 108.8 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CCC66856.1 - 5.4e-09 36.5 6.5 5.4e-09 36.5 6.5 2.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 CCC66856.1 - 1.2e-07 31.7 4.2 1.2e-07 31.7 4.2 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CCC66856.1 - 9.9e-07 29.1 7.9 9.9e-07 29.1 7.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 CCC66856.1 - 0.00022 21.7 3.9 0.00022 21.7 3.9 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CCC66856.1 - 0.007 16.3 1.3 0.007 16.3 1.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 CCC66856.1 - 0.65 10.2 15.0 0.33 11.2 9.9 2.7 2 1 1 3 3 3 0 4Fe-4S dicluster domain Autophagy_act_C PF03987.15 CCC66857.1 - 1.5e-10 41.5 0.4 3.7e-10 40.2 0.4 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain MIP PF00230.20 CCC66858.1 - 3.7e-73 246.0 5.1 5.5e-73 245.4 5.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein Podoplanin PF05808.11 CCC66858.1 - 2.5 8.2 6.0 0.71 10.0 1.8 2.2 2 0 0 2 2 2 0 Podoplanin Ribosomal_L7Ae PF01248.26 CCC66859.1 - 1.9e-23 82.0 0.6 3.1e-23 81.3 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ferric_reduct PF01794.19 CCC66860.1 - 2.8e-27 95.3 21.2 1.5e-26 93.0 15.6 3.2 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 CCC66860.1 - 1.4e-20 73.4 0.0 2.9e-20 72.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 CCC66860.1 - 1.5e-20 73.9 0.0 2.5e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Sugar_tr PF00083.24 CCC66861.1 - 6.7e-169 562.5 32.2 7.8e-169 562.3 32.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC66861.1 - 1.1e-28 100.2 19.0 1.1e-28 100.2 19.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 CCC66861.1 - 0.37 11.1 5.9 0.38 11.0 0.1 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) Rhodanese PF00581.20 CCC66862.1 - 3.1e-12 46.9 0.0 3.6e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain LnmK_N_HDF PF18238.1 CCC66862.1 - 0.056 13.2 0.0 0.07 12.9 0.0 1.1 1 0 0 1 1 1 0 LnmK N-terminal Hot Dog Fold domain SBF PF01758.16 CCC66863.1 - 2.1e-49 167.9 13.5 2.1e-49 167.9 13.5 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family Flo11 PF10182.9 CCC66864.1 - 2.4e-61 206.3 0.6 2.4e-61 206.3 0.6 2.3 2 0 0 2 2 2 1 Flo11 domain Zn_clus PF00172.18 CCC66865.1 - 3.5e-08 33.4 11.7 3.5e-08 33.4 11.7 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3699 PF12480.8 CCC66865.1 - 0.044 14.0 0.1 0.099 12.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) Epimerase PF01370.21 CCC66867.1 - 1.3e-13 50.9 0.0 2e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCC66867.1 - 1.8e-13 50.1 0.1 2.5e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CCC66867.1 - 2.2e-07 30.9 0.0 4.1e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CCC66867.1 - 2.1e-06 27.1 0.0 5.4e-05 22.5 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 CCC66867.1 - 0.00044 19.7 0.1 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CCC66867.1 - 0.013 14.7 0.1 0.024 13.8 0.1 1.5 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 CCC66867.1 - 0.025 15.0 0.0 0.046 14.2 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.25 CCC66867.1 - 0.029 13.8 0.1 0.12 11.8 0.0 2.1 4 0 0 4 4 4 0 short chain dehydrogenase Shikimate_DH PF01488.20 CCC66867.1 - 0.035 14.2 0.1 0.062 13.4 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 CCC66867.1 - 0.048 13.2 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 CCC66867.1 - 0.058 12.5 0.0 0.079 12.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_11 PF08241.12 CCC66868.1 - 2.9e-17 63.1 0.0 5e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCC66868.1 - 5.7e-15 55.8 0.0 1.7e-14 54.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC66868.1 - 2.7e-13 50.5 0.0 1.1e-11 45.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCC66868.1 - 1.5e-10 41.2 0.0 3.9e-10 39.8 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC66868.1 - 1.8e-08 34.3 0.0 5.1e-08 32.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CCC66868.1 - 0.0035 16.7 0.0 0.0054 16.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 CCC66868.1 - 0.0044 16.8 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.10 CCC66868.1 - 0.022 14.3 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.11 CCC66868.1 - 0.031 13.2 0.0 0.046 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MTS PF05175.14 CCC66868.1 - 0.034 13.7 0.0 0.067 12.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 CCC66868.1 - 0.087 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 CCC66868.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aldo_ket_red PF00248.21 CCC66869.1 - 4.7e-64 216.4 0.0 5.3e-64 216.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.16 CCC66870.1 - 7.3e-38 130.4 33.2 7.3e-38 130.4 33.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCC66870.1 - 0.00059 18.4 4.2 0.00097 17.7 4.2 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.20 CCC66870.1 - 0.046 12.0 23.0 0.004 15.5 14.0 3.0 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SKG6 PF08693.10 CCC66872.1 - 3.6e-07 29.5 1.5 1e-06 28.1 1.5 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF2681 PF10883.8 CCC66872.1 - 0.054 13.9 0.2 0.39 11.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) LapA_dom PF06305.11 CCC66872.1 - 0.076 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Myb_DNA-binding PF00249.31 CCC66873.1 - 3.3e-29 100.8 13.3 1.1e-12 48.0 0.1 3.7 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCC66873.1 - 2.5e-28 98.1 3.9 1.5e-10 41.1 0.0 3.8 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 CCC66873.1 - 3.2e-05 23.9 0.8 0.36 10.9 0.0 3.8 1 1 2 3 3 3 2 SLIDE Rap1_C PF11626.8 CCC66873.1 - 0.0073 16.4 0.3 11 6.2 0.0 3.8 3 1 0 3 3 3 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain PEPCK_ATP PF01293.20 CCC66874.1 - 1.4e-218 726.3 0.0 1.6e-218 726.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase SelA PF03841.13 CCC66874.1 - 0.047 12.7 0.0 0.088 11.8 0.0 1.4 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase AAA_33 PF13671.6 CCC66874.1 - 0.05 13.8 0.0 0.16 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CCC66874.1 - 0.074 12.4 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 KaiC PIN_4 PF13638.6 CCC66875.1 - 4.1e-12 46.5 0.1 4.1e-12 46.5 0.1 2.6 2 0 0 2 2 2 1 PIN domain Pcc1 PF09341.10 CCC66876.1 - 5.6e-19 68.0 0.0 6.4e-19 67.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DAGK_cat PF00781.24 CCC66877.1 - 1.3e-09 37.7 0.0 2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ubiquitin PF00240.23 CCC66879.1 - 3.7e-34 116.3 0.6 4.9e-34 115.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CCC66879.1 - 6.1e-31 106.1 10.4 9.3e-31 105.5 10.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CCC66879.1 - 2.2e-16 59.4 0.7 3e-16 59.0 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCC66879.1 - 2e-05 24.9 0.1 7.4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CCC66879.1 - 0.0036 17.6 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CCC66879.1 - 0.0038 17.1 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCC66879.1 - 0.0073 16.4 0.1 0.015 15.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CCC66879.1 - 0.014 15.4 1.0 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CCC66879.1 - 0.024 15.2 0.1 0.031 14.8 0.1 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CCC66879.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain PTR2 PF00854.21 CCC66880.1 - 1.9e-100 336.5 8.2 9e-100 334.3 8.2 1.8 1 1 0 1 1 1 1 POT family CcmH PF03918.14 CCC66880.1 - 0.11 11.8 0.0 19 4.5 0.0 3.1 2 1 1 3 3 3 0 Cytochrome C biogenesis protein NADH_B2 PF14813.6 CCC66880.1 - 0.56 10.0 2.8 3.5 7.5 0.0 3.1 3 0 0 3 3 3 0 NADH dehydrogenase 1 beta subcomplex subunit 2 SRP40_C PF05022.12 CCC66881.1 - 8.6e-23 81.0 3.4 8.6e-23 81.0 3.4 2.9 3 0 0 3 3 3 1 SRP40, C-terminal domain LIM PF00412.22 CCC66882.1 - 5.9e-14 52.0 27.0 5.4e-09 36.2 9.2 2.5 2 0 0 2 2 2 2 LIM domain TNFR_c6 PF00020.18 CCC66882.1 - 8.5 6.9 17.2 0.4 11.1 0.4 4.1 3 1 0 3 3 3 0 TNFR/NGFR cysteine-rich region DUF3336 PF11815.8 CCC66883.1 - 3.4e-32 111.1 3.4 9.3e-32 109.6 3.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CCC66883.1 - 3.9e-25 89.2 0.0 1e-24 87.9 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase Nitroreductase PF00881.24 CCC66883.1 - 0.025 14.6 0.1 0.049 13.7 0.1 1.4 1 0 0 1 1 1 0 Nitroreductase family SNARE_assoc PF09335.11 CCC66884.1 - 8.1e-16 58.6 10.2 1.2e-15 58.0 5.6 2.8 2 1 1 3 3 3 1 SNARE associated Golgi protein TctB PF07331.11 CCC66884.1 - 0.00023 21.4 6.5 0.00023 21.4 6.5 2.2 2 0 0 2 2 2 1 Tripartite tricarboxylate transporter TctB family Ninjurin PF04923.12 CCC66884.1 - 0.095 12.6 3.8 10 6.1 0.0 2.6 2 0 0 2 2 2 0 Ninjurin DUF4231 PF14015.6 CCC66884.1 - 0.16 12.4 4.2 0.6 10.6 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) DUF3810 PF12725.7 CCC66884.1 - 1.1 8.6 7.4 0.24 10.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Tetraspanin PF00335.20 CCC66884.1 - 4.9 6.8 8.6 16 5.1 2.3 2.7 2 1 0 2 2 2 0 Tetraspanin family VIT1 PF01988.19 CCC66884.1 - 5.2 6.9 7.8 0.93 9.3 3.8 1.8 2 1 0 2 2 2 0 VIT family Peptidase_M48 PF01435.18 CCC66885.1 - 8.9e-31 107.2 0.0 2.2e-30 105.9 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M48 HA2 PF04408.23 CCC66886.1 - 2.1e-21 76.2 0.2 8.8e-21 74.2 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCC66886.1 - 5.2e-16 58.8 0.0 2.6e-15 56.5 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CCC66886.1 - 2.7e-13 50.2 1.5 4.1e-13 49.6 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCC66886.1 - 1e-07 31.9 1.7 1e-07 31.9 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCC66886.1 - 2.5e-06 27.8 0.1 6.6e-06 26.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CCC66886.1 - 6e-05 22.4 0.0 0.00016 21.1 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 CCC66886.1 - 0.0026 17.5 0.1 1.9 8.2 0.0 2.4 1 1 1 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.6 CCC66886.1 - 0.0028 18.0 0.1 0.0088 16.4 0.1 1.8 2 0 0 2 2 1 1 AAA domain ResIII PF04851.15 CCC66886.1 - 0.003 17.6 0.1 3.1 7.8 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCC66886.1 - 0.0036 17.1 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CCC66886.1 - 0.0053 15.9 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 CCC66886.1 - 0.015 15.3 0.5 0.15 12.1 0.5 2.6 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 CCC66886.1 - 0.028 13.8 0.0 0.07 12.5 0.0 1.6 1 0 0 1 1 1 0 KaiC PhoH PF02562.16 CCC66886.1 - 0.041 13.3 0.0 0.13 11.7 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.27 CCC66886.1 - 0.071 13.6 0.2 0.32 11.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 CCC66886.1 - 0.082 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CCC66886.1 - 0.11 12.1 0.1 0.32 10.6 0.1 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.14 CCC66886.1 - 0.12 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_29 PF13555.6 CCC66886.1 - 0.17 11.7 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.26 CCC66886.1 - 0.17 11.6 0.0 0.42 10.3 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Vps5 PF09325.10 CCC66888.1 - 1.6e-31 109.7 12.8 2.5e-31 109.0 12.8 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CCC66888.1 - 1.5e-12 47.5 0.6 5.3e-12 45.7 0.6 2.0 1 0 0 1 1 1 1 PX domain Bromodomain PF00439.25 CCC66888.1 - 1.2 9.3 4.3 0.58 10.3 0.5 2.6 3 0 0 3 3 3 0 Bromodomain Lactamase_B_4 PF13691.6 CCC66889.1 - 3.5e-27 93.9 0.0 8.6e-27 92.6 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B_2 PF12706.7 CCC66889.1 - 1.4e-10 41.1 0.0 0.00023 20.7 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain DASH_Dad2 PF08654.10 CCC66890.1 - 1.8e-29 102.0 1.8 2.5e-29 101.6 1.8 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 T3SchapCesA PF11439.8 CCC66890.1 - 0.026 14.7 0.1 0.086 13.0 0.0 1.9 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA FlaC_arch PF05377.11 CCC66890.1 - 0.028 14.8 0.9 0.028 14.8 0.9 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Duo1 PF08651.10 CCC66890.1 - 0.035 13.9 1.1 0.072 12.9 1.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 NuiA PF07924.11 CCC66890.1 - 0.098 13.1 1.2 0.6 10.5 0.0 2.1 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein Nucleoporin_N PF08801.11 CCC66891.1 - 4.9e-49 167.3 9.1 8.5e-49 166.5 9.1 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Sir1 PF11603.8 CCC66892.1 - 7.8e-44 149.0 0.5 7.4e-29 100.7 0.0 3.0 2 0 0 2 2 2 2 Regulatory protein Sir1 Helicase_C PF00271.31 CCC66892.1 - 4.1e-05 23.9 0.1 0.00031 21.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain YhcG_C PF06250.11 CCC66892.1 - 0.092 12.6 0.7 1.4 8.7 0.1 2.6 2 0 0 2 2 2 0 YhcG PDDEXK nuclease domain THF_DHG_CYH PF00763.23 CCC66893.1 - 2.9e-26 92.0 0.0 1.1e-25 90.1 0.0 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 CCC66893.1 - 1.7e-17 63.2 0.0 4.2e-11 42.4 0.0 2.7 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain FTP PF07504.13 CCC66893.1 - 0.071 13.0 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif MRP-L20 PF12824.7 CCC66894.1 - 3.5e-44 150.8 2.3 4.4e-44 150.6 2.3 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Syntaxin-18_N PF10496.9 CCC66895.1 - 3.6e-14 52.8 0.6 3.6e-14 52.8 0.6 2.3 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 CCC66895.1 - 9.9e-06 25.5 0.1 2.4e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 SNARE domain SecG PF03840.14 CCC66895.1 - 0.021 14.9 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Preprotein translocase SecG subunit Spore_III_AB PF09548.10 CCC66895.1 - 0.32 11.1 0.1 0.32 11.1 0.1 3.1 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) GTP_EFTU PF00009.27 CCC66896.1 - 1.4e-43 148.7 0.1 1.8e-43 148.3 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.10 CCC66896.1 - 4.9e-13 49.2 5.1 4.9e-13 49.2 5.1 2.2 2 0 0 2 2 2 1 HBS1 N-terminus GTP_EFTU_D3 PF03143.17 CCC66896.1 - 3.3e-08 33.8 0.0 1e-07 32.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 CCC66896.1 - 2.9e-06 27.3 0.0 5.7e-05 23.2 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 CCC66896.1 - 0.0063 16.7 0.1 1.3 9.3 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU_D2 PF03144.25 CCC66896.1 - 0.0097 16.3 0.2 0.023 15.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Dynamin_N PF00350.23 CCC66896.1 - 0.092 12.8 0.1 22 5.1 0.0 2.9 1 1 1 2 2 2 0 Dynamin family Spore_Cse60 PF10957.8 CCC66896.1 - 0.42 10.7 2.3 6.1 6.9 0.1 2.7 2 0 0 2 2 2 0 Sporulation protein Cse60 PBP1_TM PF14812.6 CCC66896.1 - 6.6 7.2 11.2 4.7 7.7 1.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal GST_C PF00043.25 CCC66897.1 - 2.3e-09 37.4 0.0 8.3e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCC66897.1 - 5.4e-06 26.3 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CCC66897.1 - 1.5e-05 25.3 0.0 3.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Epimerase PF01370.21 CCC66898.1 - 5.6e-17 62.0 0.1 9.8e-17 61.2 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCC66898.1 - 9.4e-12 44.5 0.5 1.3e-11 44.1 0.5 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CCC66898.1 - 1.5e-09 37.4 0.3 9.1e-06 25.0 0.2 2.3 2 1 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 CCC66898.1 - 3.2e-07 30.4 0.0 4.8e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CCC66898.1 - 6.5e-07 29.1 0.6 5.1e-06 26.1 0.6 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 CCC66898.1 - 5.5e-06 26.0 0.1 0.00016 21.2 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.13 CCC66898.1 - 0.00011 21.9 0.1 0.001 18.7 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family KR PF08659.10 CCC66898.1 - 0.001 19.1 0.0 0.0025 17.7 0.0 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCC66898.1 - 0.029 13.5 0.4 0.12 11.5 0.0 2.1 2 1 0 3 3 3 0 Polysaccharide biosynthesis protein Response_reg PF00072.24 CCC66898.1 - 0.046 13.9 0.0 0.37 11.0 0.0 2.2 2 0 0 2 2 2 0 Response regulator receiver domain NAD_binding_2 PF03446.15 CCC66898.1 - 0.14 12.3 0.1 6.1 7.0 0.0 2.4 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pox_G7 PF05503.12 CCC66900.1 - 0.051 12.5 0.3 0.074 12.0 0.3 1.1 1 0 0 1 1 1 0 Poxvirus G7-like GST_N_2 PF13409.6 CCC66901.1 - 3.4e-22 78.5 0.0 1.3e-21 76.6 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCC66901.1 - 7.9e-11 41.8 0.1 2.3e-10 40.3 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCC66901.1 - 0.001 19.4 0.0 2.2 8.8 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Calici_coat_C PF08435.11 CCC66903.1 - 0.002 17.7 0.6 0.0035 16.9 0.6 1.4 1 0 0 1 1 1 1 Calicivirus coat protein C-terminal Put_Phosphatase PF06888.12 CCC66903.1 - 0.012 15.0 0.8 0.052 12.9 0.1 2.1 1 1 1 2 2 2 0 Putative Phosphatase YscO PF07321.12 CCC66903.1 - 0.021 14.8 1.8 0.021 14.8 1.8 2.4 2 0 0 2 2 2 0 Type III secretion protein YscO zf-CCCH_7 PF18586.1 CCC66903.1 - 0.12 12.7 1.3 0.7 10.3 0.4 2.3 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 Peptidase_S46 PF10459.9 CCC66903.1 - 0.16 10.5 9.1 0.21 10.2 9.1 1.2 1 0 0 1 1 1 0 Peptidase S46 DUF5102 PF17104.5 CCC66903.1 - 0.17 11.9 20.7 0.85 9.6 0.2 3.5 2 2 1 3 3 3 0 Domain of unknown function (DUF5102) TORC_N PF12884.7 CCC66903.1 - 0.57 11.0 6.7 2.3 9.0 0.5 3.1 2 2 0 2 2 2 0 Transducer of regulated CREB activity, N terminus YafQ_toxin PF15738.5 CCC66903.1 - 1.1 9.6 7.0 0.17 12.2 1.0 2.5 2 1 0 2 2 2 0 Bacterial toxin of type II toxin-antitoxin system, YafQ Haspin_kinase PF12330.8 CCC66904.1 - 8e-130 433.0 8.8 8e-130 433.0 8.8 4.1 2 1 0 3 3 3 1 Haspin like kinase domain WD40 PF00400.32 CCC66905.1 - 3.7e-31 106.7 18.8 7.6e-09 36.1 0.0 7.9 7 1 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC66905.1 - 1.2e-14 54.4 0.0 0.066 13.5 0.0 6.0 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.11 CCC66905.1 - 2e-05 24.5 0.0 5.2e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 TUP1-like enhancer of split PD40 PF07676.12 CCC66905.1 - 5.7e-05 22.9 0.0 8.6 6.4 0.0 5.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 CCC66905.1 - 0.00018 20.9 0.4 0.0031 16.9 0.0 3.1 4 1 0 5 5 5 1 WD40-like domain eIF2A PF08662.11 CCC66905.1 - 0.00078 19.4 0.0 1.8 8.4 0.0 4.0 5 0 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCC66905.1 - 0.0035 16.3 0.1 1.4 7.8 0.0 3.7 3 1 1 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HIRA_B PF09453.10 CCC66905.1 - 0.012 15.5 1.2 0.012 15.5 1.2 2.2 2 0 0 2 2 2 0 HIRA B motif Nbas_N PF15492.6 CCC66905.1 - 0.015 14.7 0.4 0.087 12.1 0.0 2.6 4 0 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Aconitase PF00330.20 CCC66906.1 - 5.3e-158 526.8 0.0 6.4e-158 526.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCC66906.1 - 3.1e-43 147.3 0.0 6.7e-43 146.2 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain SH3_1 PF00018.28 CCC66907.1 - 2.6e-37 126.2 3.8 5.5e-12 45.1 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.12 CCC66907.1 - 1.4e-32 111.3 0.0 3e-32 110.3 0.0 1.6 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.6 CCC66907.1 - 1.1e-31 108.5 6.7 1.4e-10 40.9 0.3 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.17 CCC66907.1 - 2.4e-30 104.0 0.0 2.6e-08 33.4 0.0 4.6 4 0 0 4 4 4 4 Variant SH3 domain SAM_4 PF18017.1 CCC66907.1 - 0.00073 19.5 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Molydop_binding PF01568.21 CCC66907.1 - 0.075 13.1 0.0 0.87 9.6 0.0 2.5 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain SpoVAC_SpoVAEB PF03862.13 CCC66907.1 - 4.5 7.6 7.5 47 4.3 0.3 3.8 3 1 1 4 4 4 0 SpoVAC/SpoVAEB sporulation membrane protein Rsc14 PF08586.10 CCC66908.1 - 2.8e-28 98.6 1.5 1.8e-27 96.0 0.6 2.4 2 1 0 2 2 2 1 RSC complex, Rsc14/Ldb7 subunit HNH_5 PF14279.6 CCC66908.1 - 0.013 15.4 0.7 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 HNH endonuclease ERG4_ERG24 PF01222.17 CCC66910.1 - 3.4e-185 615.9 31.0 3.9e-185 615.7 31.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family HEAT PF02985.22 CCC66911.1 - 4.5e-15 54.5 10.6 0.0046 17.1 0.1 10.1 10 0 0 10 10 9 2 HEAT repeat HEAT_EZ PF13513.6 CCC66911.1 - 5.5e-13 49.1 13.5 3.8e-08 33.7 0.0 9.2 9 2 2 11 11 11 2 HEAT-like repeat IBN_N PF03810.19 CCC66911.1 - 2.3e-10 40.2 3.7 2.3e-10 40.2 3.7 3.4 3 1 0 3 3 2 1 Importin-beta N-terminal domain Arm PF00514.23 CCC66911.1 - 7.6e-07 29.0 6.6 0.43 10.7 0.0 7.0 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 CCC66911.1 - 1.7e-06 28.3 4.4 0.73 10.3 0.0 6.6 3 2 5 8 8 8 5 HEAT repeats Cnd1 PF12717.7 CCC66911.1 - 4.2e-06 26.9 10.5 0.0013 18.8 0.1 5.4 4 3 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 CCC66911.1 - 8.8e-05 22.2 0.6 1 8.9 0.0 4.3 2 1 1 4 4 4 1 CLASP N terminal Tti2 PF10521.9 CCC66911.1 - 0.0024 17.5 0.0 1.1 8.7 0.0 2.9 2 1 0 2 2 2 1 Tti2 family Sec7_N PF12783.7 CCC66911.1 - 0.031 14.2 3.5 0.26 11.2 0.5 3.5 3 1 0 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Urb2 PF10441.9 CCC66911.1 - 0.034 14.1 1.1 0.073 13.0 0.2 2.1 2 0 0 2 2 2 0 Urb2/Npa2 family DUF5063 PF16702.5 CCC66911.1 - 0.058 13.8 2.3 7.9 6.8 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF5063) RTP1_C1 PF10363.9 CCC66911.1 - 0.24 11.6 2.4 19 5.5 0.7 4.3 3 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF3890 PF13029.6 CCC66911.1 - 0.36 11.3 2.8 16 6.0 0.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3890) PE PF00934.20 CCC66911.1 - 2.7 8.4 7.6 0.86 10.0 0.7 3.1 3 0 0 3 3 3 0 PE family Mito_carr PF00153.27 CCC66912.1 - 4.4e-53 177.2 0.5 3.6e-17 62.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_4 PF12799.7 CCC66913.1 - 0.00062 20.1 18.6 0.062 13.7 3.9 6.0 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CCC66913.1 - 0.0013 18.6 8.0 11 6.3 0.0 5.8 5 0 0 5 5 5 2 Leucine Rich repeat LRR_8 PF13855.6 CCC66913.1 - 0.11 12.2 7.3 0.72 9.7 0.2 4.3 2 1 1 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 CCC66913.1 - 0.93 10.3 17.6 17 6.5 0.1 7.4 7 1 0 7 7 7 0 Leucine Rich Repeat DNA_pol_phi PF04931.13 CCC66914.1 - 2 6.4 11.7 3.5 5.6 11.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi NOA36 PF06524.12 CCC66914.1 - 2 7.6 18.3 0.41 9.9 13.4 2.1 2 0 0 2 2 2 0 NOA36 protein Fungal_trans PF04082.18 CCC66915.1 - 7e-21 74.4 10.0 2.7e-20 72.5 10.0 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC66915.1 - 1.1e-06 28.6 10.6 1.1e-06 28.6 10.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mod_r PF07200.13 CCC66915.1 - 0.011 15.9 2.5 0.017 15.2 1.1 2.1 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Fungal_trans PF04082.18 CCC66916.1 - 1.8e-27 96.0 6.5 1.8e-27 96.0 6.5 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC66916.1 - 2.7e-08 33.8 12.2 5.1e-08 32.9 12.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHASE3 PF05227.13 CCC66916.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 CHASE3 domain 6PF2K PF01591.18 CCC66917.1 - 1.1e-60 204.7 2.7 1.5e-60 204.3 2.7 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CCC66917.1 - 3.6e-20 72.5 0.0 6.3e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CCC66917.1 - 0.00012 22.3 0.0 0.00043 20.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.10 CCC66917.1 - 0.027 13.9 0.4 0.041 13.3 0.4 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_24 PF13479.6 CCC66917.1 - 0.041 13.6 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NUC173 PF08161.12 CCC66918.1 - 6.7e-73 244.7 1.4 5.3e-70 235.2 0.4 3.8 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.22 CCC66918.1 - 6.6e-06 25.9 0.1 1.1 9.7 0.0 5.5 5 0 0 5 5 5 1 HEAT repeat RTP1_C1 PF10363.9 CCC66918.1 - 0.001 19.3 1.2 3.5 7.9 0.1 3.7 3 0 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Ipi1_N PF12333.8 CCC66918.1 - 0.017 15.7 1.1 17 6.1 0.1 3.7 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation DUF3437 PF11919.8 CCC66918.1 - 0.023 14.6 0.3 5.8 6.9 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3437) Inh PF02974.14 CCC66918.1 - 0.038 14.1 0.0 0.44 10.6 0.0 2.3 2 0 0 2 2 2 0 Protease inhibitor Inh HEAT_2 PF13646.6 CCC66918.1 - 0.043 14.2 0.1 37 4.8 0.0 4.0 3 0 0 3 3 3 0 HEAT repeats BORCS8 PF10167.9 CCC66918.1 - 0.077 12.9 0.1 0.24 11.3 0.1 1.8 1 0 0 1 1 1 0 BLOC-1-related complex sub-unit 8 FANCI_S3 PF14677.6 CCC66918.1 - 1.6 8.4 6.6 5.4 6.6 2.0 3.2 2 0 0 2 2 2 0 FANCI solenoid 3 Bromo_TP PF07524.13 CCC66919.1 - 1.4e-09 37.8 0.1 2.7e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 CCC66919.1 - 0.00044 20.4 1.6 0.00052 20.2 0.1 1.9 2 0 0 2 2 2 1 Histone-fold protein NusB PF01029.18 CCC66919.1 - 0.029 14.6 1.0 4.7 7.5 0.6 2.5 2 0 0 2 2 2 0 NusB family TFIID-18kDa PF02269.16 CCC66919.1 - 0.047 13.7 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Clat_adaptor_s PF01217.20 CCC66920.1 - 1.3e-09 38.1 0.3 2.3e-09 37.3 0.1 1.4 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Rad21_Rec8_N PF04825.13 CCC66921.1 - 7.2e-16 58.3 0.2 1.7e-15 57.1 0.2 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CCC66921.1 - 0.03 13.6 0.0 0.072 12.4 0.0 1.6 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein AKAP7_RIRII_bdg PF10470.9 CCC66921.1 - 0.58 10.3 5.5 1.2 9.2 0.3 2.8 3 0 0 3 3 3 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein ICL PF00463.21 CCC66922.1 - 1.7e-163 544.9 0.0 2e-163 544.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CCC66922.1 - 5e-07 29.4 0.0 7.7e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase GT-D PF08759.11 CCC66922.1 - 0.066 12.9 0.9 0.12 12.0 0.9 1.4 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold Mannosyl_trans3 PF11051.8 CCC66923.1 - 9.8e-82 274.4 3.2 2.1e-81 273.3 0.0 2.6 3 0 0 3 3 3 1 Mannosyltransferase putative Arc_C PF18162.1 CCC66924.1 - 0.18 11.7 0.2 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Arc C-lobe PhoLip_ATPase_C PF16212.5 CCC66925.1 - 4.4e-78 262.5 28.1 4.4e-78 262.5 28.1 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCC66925.1 - 1.8e-17 62.8 1.3 1.8e-17 62.8 1.3 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CCC66925.1 - 1.4e-12 47.5 0.0 6.8e-12 45.3 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCC66925.1 - 2.1e-09 38.0 1.1 8.4e-06 26.2 0.3 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CCC66925.1 - 6e-05 22.6 0.7 0.00016 21.3 0.0 2.1 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CCC66925.1 - 0.0015 18.4 0.2 0.0044 16.8 0.2 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4131 PF13567.6 CCC66925.1 - 0.18 11.4 2.3 9.9 5.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RRM_1 PF00076.22 CCC66926.1 - 4.3e-86 282.7 7.6 4.1e-22 77.8 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 CCC66926.1 - 2.2e-18 66.2 2.3 7.3e-18 64.5 0.1 2.6 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 CCC66926.1 - 1.1e-12 47.6 0.0 0.011 15.4 0.0 4.3 1 1 3 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC66926.1 - 1.2e-06 28.6 2.0 0.0079 16.3 0.0 4.9 4 3 0 4 4 4 1 RNA recognition motif RRM_3 PF08777.11 CCC66926.1 - 7.9e-06 25.9 8.5 0.76 9.8 0.1 5.1 5 0 0 5 5 5 2 RNA binding motif Nup35_RRM PF05172.13 CCC66926.1 - 1.8e-05 24.6 0.1 0.037 14.0 0.0 3.7 3 1 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CCC66926.1 - 2.8e-05 23.9 0.0 0.11 12.4 0.0 4.2 4 0 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CCC66926.1 - 0.0022 17.9 1.8 17 5.5 0.0 4.0 4 0 0 4 4 3 0 Nup53/35/40-type RNA recognition motif DUF4523 PF15023.6 CCC66926.1 - 0.0034 17.2 0.0 0.5 10.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF4523) YflT PF11181.8 CCC66926.1 - 0.014 15.9 10.2 1.5 9.4 1.0 3.6 2 1 1 3 3 3 0 Heat induced stress protein YflT OB_RNB PF08206.11 CCC66926.1 - 0.034 13.8 4.6 12 5.7 0.2 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain LON_substr_bdg PF02190.16 CCC66926.1 - 0.061 13.2 1.5 0.22 11.4 0.4 2.2 1 1 1 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain Bac_DNA_binding PF00216.21 CCC66926.1 - 0.095 12.9 3.7 6.9 7.0 0.3 3.4 3 0 0 3 3 3 0 Bacterial DNA-binding protein SNF2_N PF00176.23 CCC66927.1 - 1.2e-63 215.0 0.0 2.5e-63 213.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Cdh1_DBD_1 PF18196.1 CCC66927.1 - 2.4e-44 150.5 5.5 2.4e-44 150.5 5.5 3.2 2 0 0 2 2 2 1 Chromodomain helicase DNA-binding domain 1 DUF4208 PF13907.6 CCC66927.1 - 8.7e-28 96.6 0.8 8.7e-28 96.6 0.8 3.5 4 0 0 4 4 4 1 Domain of unknown function (DUF4208) Chromo PF00385.24 CCC66927.1 - 9.9e-25 86.2 4.1 1e-15 57.3 0.1 3.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.31 CCC66927.1 - 2.2e-20 73.0 0.0 8.3e-20 71.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC66927.1 - 1.5e-08 34.9 0.1 1.3e-07 31.8 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Myb_DNA-binding PF00249.31 CCC66927.1 - 0.0002 21.5 0.0 0.0012 19.0 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain CHDCT2 PF08074.11 CCC66927.1 - 0.002 18.3 0.1 0.013 15.7 0.0 2.5 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain Myb_DNA-bind_6 PF13921.6 CCC66927.1 - 0.0052 17.0 0.0 0.029 14.6 0.0 2.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 CCC66927.1 - 0.0073 16.3 0.0 0.0073 16.3 0.0 3.2 3 1 0 4 4 4 1 SLIDE Copper-fist PF00649.18 CCC66928.1 - 1.9e-19 68.9 2.6 1.9e-19 68.9 2.6 2.4 2 0 0 2 2 2 1 Copper fist DNA binding domain ChaC PF04752.12 CCC66929.1 - 3.3e-58 196.7 0.0 4.4e-58 196.3 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein Rad4 PF03835.15 CCC66930.1 - 1.5e-35 122.0 3.2 1.5e-35 122.0 3.2 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_3 PF10405.9 CCC66930.1 - 8.2e-24 83.8 0.0 1.8e-23 82.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CCC66930.1 - 1.2e-15 57.1 0.2 2.7e-15 55.9 0.2 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 CCC66930.1 - 2.9e-07 31.3 0.2 2.9e-07 31.3 0.2 3.7 3 1 0 3 3 3 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.19 CCC66930.1 - 0.0053 17.2 0.1 0.017 15.5 0.0 2.0 2 0 0 2 2 2 1 Transglutaminase-like superfamily DUF3398 PF11878.8 CCC66930.1 - 1.4 9.4 10.1 0.093 13.2 2.8 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3398) SPT2 PF08243.11 CCC66931.1 - 2.7e-27 95.5 30.1 2.7e-27 95.5 30.1 2.5 2 1 1 3 3 3 1 SPT2 chromatin protein CBFD_NFYB_HMF PF00808.23 CCC66932.1 - 2.9e-12 46.7 0.1 3.7e-12 46.3 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CCC66932.1 - 0.021 15.2 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF1732 PF08340.11 CCC66932.1 - 0.054 13.5 0.0 0.14 12.2 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) CLIP PF12032.8 CCC66932.1 - 0.12 12.6 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Regulatory CLIP domain of proteinases Sec34 PF04136.15 CCC66935.1 - 2.9e-44 150.5 5.8 2.9e-44 150.5 5.8 2.6 3 0 0 3 3 3 1 Sec34-like family DUF5377 PF17347.2 CCC66935.1 - 0.039 14.3 0.9 0.14 12.5 0.2 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5377) FRB_dom PF08771.11 CCC66935.1 - 0.63 10.5 3.5 1.4 9.4 0.0 3.4 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain UPF0160 PF03690.13 CCC66936.1 - 4.8e-127 424.0 0.0 5.5e-127 423.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Toprim_2 PF13155.6 CCC66936.1 - 0.028 14.8 0.0 0.06 13.8 0.0 1.6 1 0 0 1 1 1 0 Toprim-like Dimer_Tnp_hAT PF05699.14 CCC66937.1 - 8.4e-09 35.1 0.1 2.9e-08 33.4 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CCC66937.1 - 0.18 11.9 0.5 0.47 10.5 0.5 1.8 1 0 0 1 1 1 0 BED zinc finger RhoGAP PF00620.27 CCC66938.1 - 6.8e-39 133.1 0.6 2.8e-38 131.1 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain RasGEF_N PF00618.20 CCC66938.1 - 1.6e-20 73.3 0.9 1.9e-19 69.8 0.9 3.0 1 0 0 1 1 1 1 RasGEF N-terminal motif RasGEF PF00617.19 CCC66938.1 - 3.8e-11 43.5 11.6 5.5e-09 36.5 0.1 4.2 3 1 0 3 3 3 2 RasGEF domain PH PF00169.29 CCC66938.1 - 0.0012 19.3 0.2 0.0092 16.5 0.1 2.7 2 0 0 2 2 2 1 PH domain FlaC_arch PF05377.11 CCC66938.1 - 2.3 8.7 5.5 2.6 8.5 0.8 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) 60KD_IMP PF02096.20 CCC66939.1 - 1.9e-22 80.0 0.7 1.9e-22 80.0 0.7 1.6 2 0 0 2 2 2 1 60Kd inner membrane protein PET122 PF05476.11 CCC66940.1 - 5e-121 402.9 5.4 5.7e-121 402.7 5.4 1.0 1 0 0 1 1 1 1 PET122 NHase_alpha PF02979.16 CCC66940.1 - 0.11 11.9 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Nitrile hydratase, alpha chain Aminotran_1_2 PF00155.21 CCC66941.1 - 6.9e-19 68.2 0.0 8.7e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 CCC66941.1 - 0.00037 19.4 0.0 0.00047 19.1 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase UCH PF00443.29 CCC66942.1 - 2.7e-49 168.0 3.9 9.8e-49 166.2 3.9 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Metallophos PF00149.28 CCC66943.1 - 9.1e-38 130.8 0.1 1.2e-37 130.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CCC66943.1 - 0.012 15.8 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Cnn_1N PF07989.11 CCC66944.1 - 0.0008 19.5 7.5 0.0008 19.5 7.5 2.7 2 0 0 2 2 2 1 Centrosomin N-terminal motif 1 DUF489 PF04356.12 CCC66944.1 - 0.1 12.6 0.7 0.23 11.4 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DMPK_coil PF08826.10 CCC66944.1 - 1.9 8.7 21.3 0.085 13.0 3.2 3.2 3 0 0 3 3 3 0 DMPK coiled coil domain like TBP PF00352.21 CCC66945.1 - 2.7e-68 225.9 0.1 7.4e-33 112.4 0.1 2.2 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 CCC66945.1 - 5.6e-05 23.2 1.8 0.26 11.5 0.0 3.0 3 1 1 4 4 4 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 CCC66945.1 - 0.04 13.7 0.2 0.28 11.0 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Cohesin_load PF10345.9 CCC66946.1 - 8.4e-83 278.8 33.8 1.1e-82 278.4 33.8 1.1 1 0 0 1 1 1 1 Cohesin loading factor LSM PF01423.22 CCC66947.1 - 3.8e-16 58.5 0.0 4.4e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 LSM domain FTR1 PF03239.14 CCC66948.1 - 1.3e-94 316.9 6.6 1.5e-94 316.6 6.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family B12D PF06522.11 CCC66948.1 - 2.1 8.2 3.5 1.6 8.6 0.2 2.4 2 0 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit UCH PF00443.29 CCC66949.1 - 1.5e-58 198.3 0.6 1.5e-58 198.3 0.6 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCC66949.1 - 5.6e-24 85.3 1.3 2.1e-23 83.4 1.3 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CCC66949.1 - 4.4e-08 33.6 0.0 9.4e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 CCC66949.1 - 0.028 14.2 1.8 0.091 12.5 1.8 1.9 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF2634 PF10934.8 CCC66949.1 - 0.1 12.7 1.4 0.37 10.9 1.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2634) Asp_protease PF09668.10 CCC66950.1 - 1.1e-48 164.1 0.0 2.2e-48 163.2 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CCC66950.1 - 1.9e-17 63.6 0.0 3.5e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CCC66950.1 - 2.4e-09 37.7 0.1 4.8e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.31 CCC66950.1 - 5e-05 23.1 0.1 0.00016 21.5 0.1 1.8 1 0 0 1 1 1 1 UBA/TS-N domain RVP PF00077.20 CCC66950.1 - 0.013 15.8 0.1 0.042 14.2 0.0 2.0 2 1 0 2 2 2 0 Retroviral aspartyl protease RVP_2 PF08284.11 CCC66950.1 - 0.037 13.8 0.1 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 Retroviral aspartyl protease Pyr_redox_2 PF07992.14 CCC66951.1 - 3.9e-50 170.8 0.0 4.9e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCC66951.1 - 1.1e-11 45.1 0.0 2e-10 41.1 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCC66951.1 - 0.00044 19.6 0.0 0.59 9.3 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HTH_psq PF05225.16 CCC66952.1 - 0.00014 21.5 0.1 0.0012 18.5 0.0 2.7 2 1 0 2 2 2 1 helix-turn-helix, Psq domain DUF1298 PF06974.13 CCC66952.1 - 0.087 12.8 1.5 0.14 12.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1298) DUF1053 PF06327.14 CCC66952.1 - 0.31 11.6 6.2 1.7 9.3 0.2 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1053) PBP_dimer PF03717.15 CCC66954.1 - 0.012 16.0 4.7 0.81 10.0 3.2 2.9 1 1 1 3 3 3 0 Penicillin-binding Protein dimerisation domain PKcGMP_CC PF16808.5 CCC66954.1 - 0.025 14.4 4.4 0.12 12.3 4.4 2.1 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Med30 PF11315.8 CCC66954.1 - 0.085 13.0 6.1 0.16 12.1 6.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit 30 UPF0242 PF06785.11 CCC66954.1 - 0.47 10.5 11.3 0.78 9.8 11.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Ribosomal_S9 PF00380.19 CCC66955.1 - 1.2e-32 112.9 0.2 1.4e-32 112.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.18 CCC66956.1 - 7.4e-67 224.7 4.3 1.2e-66 224.0 4.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_60s PF00428.19 CCC66957.1 - 2.3e-21 76.2 8.4 2.7e-21 75.9 8.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TPP_enzyme_N PF02776.18 CCC66958.1 - 5.4e-28 97.7 0.0 1.1e-27 96.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCC66958.1 - 5e-21 74.9 0.0 9.1e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCC66958.1 - 2.4e-13 50.2 0.0 4.3e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Hpr_kinase_N PF02603.16 CCC66958.1 - 0.077 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 HPr Serine kinase N terminus Pkinase PF00069.25 CCC66959.1 - 3.9e-63 213.3 0.0 4.6e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC66959.1 - 2.6e-26 92.5 0.0 3.3e-26 92.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CCC66959.1 - 0.0049 16.5 0.4 0.0079 15.8 0.4 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CCC66959.1 - 0.0057 15.5 0.0 1.1 8.0 0.0 2.1 1 1 0 2 2 2 2 Fungal protein kinase APH PF01636.23 CCC66959.1 - 0.013 15.5 0.1 0.024 14.6 0.1 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family FAS_meander PF17951.1 CCC66959.1 - 0.17 11.7 0.4 0.31 10.9 0.4 1.3 1 0 0 1 1 1 0 Fatty acid synthase meander beta sheet domain Ldh_1_C PF02866.18 CCC66960.1 - 3.9e-42 144.0 0.1 7.1e-42 143.2 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CCC66960.1 - 1.5e-41 141.8 0.1 2.5e-41 141.1 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CCC66960.1 - 0.0015 17.6 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CCC66960.1 - 0.0068 16.8 0.0 0.022 15.2 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF2547 PF10818.8 CCC66961.1 - 3.2 8.7 5.5 0.89 10.5 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Macoilin PF09726.9 CCC66961.1 - 4.2 5.8 9.0 4.9 5.6 9.0 1.1 1 0 0 1 1 1 0 Macoilin family SRP1_TIP1 PF00660.17 CCC66962.1 - 2.1e-08 34.1 0.5 2.1e-08 34.1 0.5 1.9 2 0 0 2 2 2 1 Seripauperin and TIP1 family SPX PF03105.19 CCC66962.1 - 0.0013 18.8 6.7 0.0013 18.7 6.7 1.1 1 0 0 1 1 1 1 SPX domain Apt1 PF10351.9 CCC66962.1 - 3.4 6.4 19.9 4.6 6.0 19.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tmemb_cc2 PF10267.9 CCC66962.1 - 6.8 5.7 10.8 12 4.9 10.8 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein MDFI PF15316.6 CCC66962.1 - 7.4 6.6 10.5 13 5.9 10.5 1.3 1 0 0 1 1 1 0 MyoD family inhibitor RIC1 PF07064.13 CCC66963.1 - 2.2e-13 50.2 4.5 2.2e-13 50.2 4.5 2.4 2 1 0 2 2 2 1 RIC1 YonK PF09642.10 CCC66963.1 - 0.0072 16.4 0.2 0.066 13.4 0.2 2.8 1 0 0 1 1 1 1 YonK protein COX6B PF02297.17 CCC66964.1 - 4.5e-20 71.7 5.2 5.3e-20 71.4 5.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.14 CCC66964.1 - 0.096 12.7 0.3 0.12 12.3 0.3 1.2 1 0 0 1 1 1 0 APOBEC-like C-terminal domain MYT1 PF08474.11 CCC66964.1 - 0.11 12.4 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 Myelin transcription factor 1 CX9C PF16860.5 CCC66964.1 - 0.12 12.5 1.2 0.19 11.8 1.2 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, ketoacyl-synt PF00109.26 CCC66964.1 - 0.15 11.6 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain HATPase_c_3 PF13589.6 CCC66965.1 - 1.4e-10 41.1 0.2 4.6e-10 39.5 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 CCC66965.1 - 5.3e-10 39.0 0.2 1.5e-09 37.6 0.2 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 CCC66965.1 - 6.7e-06 26.6 0.1 1.7e-05 25.2 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dimer_Tnp_hAT PF05699.14 CCC66966.1 - 8.4e-09 35.1 0.1 2.9e-08 33.4 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CCC66966.1 - 0.18 11.9 0.5 0.47 10.5 0.5 1.8 1 0 0 1 1 1 0 BED zinc finger Nramp PF01566.18 CCC66967.1 - 3.9e-95 318.8 13.9 5.2e-95 318.4 13.9 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Bromodomain PF00439.25 CCC66968.1 - 1.5e-07 31.4 0.8 4.5e-07 29.8 0.2 2.1 2 0 0 2 2 2 1 Bromodomain HA2 PF04408.23 CCC66969.1 - 1.3e-29 102.6 0.1 7.4e-29 100.2 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCC66969.1 - 1.6e-13 51.0 0.3 2e-11 44.2 0.0 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CCC66969.1 - 6.1e-13 49.0 0.0 1.6e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CCC66969.1 - 6.4e-08 32.6 0.0 1.7e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCC66969.1 - 7.1e-06 26.3 0.2 2.8e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain HTH_37 PF13744.6 CCC66969.1 - 0.0023 17.8 0.3 0.0081 16.1 0.3 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain ATPase PF06745.13 CCC66969.1 - 0.003 16.9 1.2 0.014 14.8 0.0 2.7 3 0 0 3 3 3 1 KaiC PhoH PF02562.16 CCC66969.1 - 0.015 14.7 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.6 CCC66969.1 - 0.016 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCC66969.1 - 0.024 15.2 0.2 0.2 12.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CCC66969.1 - 0.025 14.9 0.0 0.071 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CCC66969.1 - 0.026 13.6 0.0 0.056 12.5 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4704 PF15787.5 CCC66969.1 - 0.072 12.3 1.2 0.087 12.1 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4704) SNF2_N PF00176.23 CCC66970.1 - 3.8e-69 233.1 0.1 6.5e-69 232.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCC66970.1 - 1.5e-15 57.5 0.0 1.7e-14 54.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HIRAN PF08797.11 CCC66970.1 - 9.9e-14 51.1 0.0 1.9e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain zf-RING_2 PF13639.6 CCC66970.1 - 1.9e-07 31.3 6.6 3.5e-07 30.5 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCC66970.1 - 7.6e-07 28.9 4.3 1.4e-06 28.0 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCC66970.1 - 1.2e-06 28.3 6.9 2.2e-06 27.5 6.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CCC66970.1 - 2.6e-06 27.2 7.8 5e-06 26.3 7.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC66970.1 - 1.8e-05 24.6 6.0 3.6e-05 23.7 6.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger ResIII PF04851.15 CCC66970.1 - 3.4e-05 23.9 0.0 0.00015 21.9 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.6 CCC66970.1 - 0.0038 17.4 8.3 0.0072 16.5 8.3 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CCC66970.1 - 0.006 16.4 5.5 0.012 15.5 5.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CCC66970.1 - 0.0089 15.9 6.7 0.021 14.7 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CCC66970.1 - 0.034 14.4 3.0 0.078 13.3 3.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCC66970.1 - 0.037 14.1 0.6 0.073 13.1 0.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_Tnp_IS91 PF14319.6 CCC66970.1 - 0.05 13.6 0.3 0.18 11.9 0.0 1.9 1 1 1 2 2 2 0 Transposase zinc-binding domain zf-RING_11 PF17123.5 CCC66970.1 - 0.099 12.4 6.3 0.2 11.4 6.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 CCC66970.1 - 0.16 11.8 6.7 0.32 10.8 6.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MIF4G_like PF09088.11 CCC66971.1 - 5.2e-45 153.6 0.9 1.2e-44 152.4 0.3 2.0 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.11 CCC66971.1 - 1.2e-25 90.6 1.4 1.1e-21 77.6 0.2 2.7 3 0 0 3 3 3 2 MIF4G like PRD PF00874.20 CCC66971.1 - 1.2 9.4 4.7 3.9 7.8 0.3 3.6 4 0 0 4 4 4 0 PRD domain Ribosomal_L15e PF00827.17 CCC66972.1 - 1.2e-88 295.9 12.9 1.5e-88 295.5 12.9 1.1 1 0 0 1 1 1 1 Ribosomal L15 AICARFT_IMPCHas PF01808.18 CCC66973.1 - 2.7e-92 309.4 0.0 4.8e-92 308.6 0.0 1.4 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CCC66973.1 - 2.8e-24 85.1 0.2 1.1e-23 83.3 0.0 2.0 2 0 0 2 2 2 1 MGS-like domain zf-C3HC4_3 PF13920.6 CCC66974.1 - 5.7e-08 32.5 9.8 9.7e-08 31.8 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCC66974.1 - 0.068 13.0 10.3 0.14 12.1 10.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Aminotran_1_2 PF00155.21 CCC66975.1 - 6.9e-80 268.9 0.0 7.9e-80 268.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SNARE PF05739.19 CCC66976.1 - 1.5e-14 53.7 0.2 3.7e-14 52.4 0.2 1.7 1 0 0 1 1 1 1 SNARE domain Syntaxin-5_N PF11416.8 CCC66976.1 - 1.3e-05 24.3 2.2 3.9e-05 22.7 0.1 2.6 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Serine_rich PF08824.10 CCC66976.1 - 0.0012 18.9 2.9 0.14 12.1 0.3 2.6 2 0 0 2 2 2 2 Serine rich protein interaction domain Syntaxin-18_N PF10496.9 CCC66976.1 - 0.0058 16.9 3.6 0.0058 16.9 3.6 2.8 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus MCPsignal PF00015.21 CCC66976.1 - 0.056 13.2 0.4 0.056 13.2 0.4 3.0 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Syntaxin PF00804.25 CCC66976.1 - 0.23 11.1 21.3 0.069 12.8 10.2 3.4 1 1 2 3 3 3 0 Syntaxin DUF1664 PF07889.12 CCC66976.1 - 1.2 9.1 11.3 1.6 8.8 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) ZapA PF05164.13 CCC66976.1 - 2.2 8.8 6.2 5 7.6 0.1 3.5 3 1 0 3 3 3 0 Cell division protein ZapA DUF948 PF06103.11 CCC66976.1 - 3.7 7.9 9.4 0.75 10.1 0.6 3.1 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Snf7 PF03357.21 CCC66977.1 - 6.6e-49 165.8 25.3 6.6e-49 165.8 25.3 1.9 1 1 1 2 2 2 1 Snf7 Env-gp36 PF09590.10 CCC66977.1 - 0.0089 14.5 0.6 0.01 14.3 0.6 1.1 1 0 0 1 1 1 1 Lentivirus surface glycoprotein EF1_GNE PF00736.19 CCC66977.1 - 0.096 12.9 3.5 0.19 11.9 3.5 1.5 1 0 0 1 1 1 0 EF-1 guanine nucleotide exchange domain DUF3573 PF12097.8 CCC66977.1 - 2.8 6.6 9.2 2.7 6.7 7.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) Sdh_cyt PF01127.22 CCC66978.1 - 2.9e-19 69.3 2.9 3.9e-19 68.9 2.9 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Abhydrolase_1 PF00561.20 CCC66979.1 - 2.8e-32 112.4 0.1 5.3e-32 111.5 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 CCC66979.1 - 7.5e-21 73.5 0.1 2.1e-20 72.1 0.1 1.8 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Hydrolase_4 PF12146.8 CCC66979.1 - 0.00016 21.1 0.0 0.45 9.7 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 CCC66979.1 - 0.0044 16.7 0.0 0.84 9.3 0.0 2.5 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CCC66979.1 - 0.054 13.3 0.1 0.87 9.3 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase YlbE PF14003.6 CCC66979.1 - 0.47 10.9 2.7 1 9.8 0.5 2.5 2 0 0 2 2 2 0 YlbE-like protein Pkinase PF00069.25 CCC66980.1 - 3e-73 246.4 0.0 4.2e-73 246.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC66980.1 - 1.3e-33 116.4 0.1 2.1e-33 115.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC66980.1 - 3e-05 23.5 0.0 6.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CCC66980.1 - 4.1e-05 22.7 0.2 4.1e-05 22.7 0.2 2.0 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CCC66980.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CCC66980.1 - 0.025 13.9 0.1 0.071 12.5 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CCC66980.1 - 0.026 13.3 0.1 0.026 13.3 0.1 2.0 2 0 0 2 2 2 0 Fungal protein kinase DASH_Hsk3 PF08227.11 CCC66981.1 - 1.3e-17 63.8 2.2 1.6e-17 63.6 2.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like UPF0449 PF15136.6 CCC66981.1 - 0.022 15.2 1.4 0.029 14.8 1.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Synaptonemal_3 PF15191.6 CCC66981.1 - 0.033 14.0 0.6 0.043 13.6 0.6 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 L31 PF09784.9 CCC66982.1 - 1.8e-44 150.3 2.8 2.7e-44 149.8 2.8 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Cmc1 PF08583.10 CCC66983.1 - 8.6e-21 73.7 0.4 1.2e-20 73.3 0.4 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Adaptin_N PF01602.20 CCC66984.1 - 1.6e-127 426.2 19.9 2e-127 425.9 19.9 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCC66984.1 - 2e-58 197.0 14.0 8.6e-57 191.7 5.3 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCC66984.1 - 7.5e-13 48.7 1.5 5.7e-06 26.6 0.1 5.7 3 2 3 6 6 6 2 HEAT repeats HEAT PF02985.22 CCC66984.1 - 5.6e-09 35.5 0.7 0.044 14.0 0.0 5.5 5 0 0 5 5 5 3 HEAT repeat CLASP_N PF12348.8 CCC66984.1 - 6.5e-05 22.6 3.8 1.5 8.4 0.0 4.6 3 2 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 CCC66984.1 - 0.00017 22.0 1.0 0.54 10.8 0.0 4.9 5 0 0 5 5 4 1 HEAT-like repeat Arm_2 PF04826.13 CCC66984.1 - 0.00088 18.8 4.3 0.0014 18.2 2.6 2.1 2 0 0 2 2 2 1 Armadillo-like RTP1_C1 PF10363.9 CCC66984.1 - 0.0041 17.3 6.8 0.63 10.2 0.1 5.2 3 2 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Phage_TAC_12 PF12363.8 CCC66984.1 - 0.013 15.9 0.3 0.99 9.8 0.1 3.0 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC Atx10homo_assoc PF09759.9 CCC66984.1 - 0.095 12.7 0.7 0.87 9.7 0.0 2.9 2 1 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain Arm PF00514.23 CCC66984.1 - 0.24 11.5 0.9 10 6.3 0.2 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat WD40 PF00400.32 CCC66985.1 - 2e-44 148.7 12.0 2.4e-07 31.3 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC66985.1 - 8.3e-10 38.8 1.3 0.016 15.5 0.0 4.6 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCC66985.1 - 8e-07 28.3 0.6 0.042 12.8 0.0 4.0 2 1 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CCC66985.1 - 2.1e-06 26.7 3.4 0.01 14.5 0.1 4.3 2 1 3 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.11 CCC66985.1 - 1.3e-05 25.2 0.3 0.0014 18.5 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 CCC66985.1 - 0.02 13.7 0.7 1.1 7.9 0.5 2.7 1 1 1 2 2 2 0 Nup133 N terminal like PD40 PF07676.12 CCC66985.1 - 0.072 13.1 0.0 19 5.4 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat KOW PF00467.29 CCC66985.1 - 0.15 12.0 0.0 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 KOW motif Peptidase_M3 PF01432.20 CCC66986.1 - 9.5e-131 437.2 0.0 1.2e-130 436.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.6 CCC66986.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M91 PF14891.6 CCC66986.1 - 0.2 11.9 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 Effector protein Mur_ligase_M PF08245.12 CCC66987.1 - 3e-05 24.1 0.0 0.00014 21.9 0.0 2.2 1 1 0 1 1 1 1 Mur ligase middle domain PCNA_C PF02747.15 CCC66987.1 - 0.18 12.0 0.1 0.37 11.0 0.1 1.5 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain She2p PF11435.8 CCC66988.1 - 1.7e-89 298.8 11.6 1.7e-89 298.8 11.6 1.3 2 0 0 2 2 2 1 RNA binding protein She2p DUF1382 PF07131.11 CCC66988.1 - 0.17 11.9 0.3 0.39 10.8 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) Myosin_head PF00063.21 CCC66989.1 - 8.2e-234 777.8 8.9 1e-233 777.5 8.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 CCC66989.1 - 7.9e-47 159.3 0.2 1.5e-46 158.5 0.2 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 CCC66989.1 - 1e-10 41.0 0.0 2.1e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCC66989.1 - 4.4e-08 32.8 0.0 9.3e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCC66989.1 - 2.3e-06 27.2 0.0 5.7e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Hpr_kinase_C PF07475.12 CCC66989.1 - 0.017 14.6 0.1 8.8 5.8 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 CCC66989.1 - 0.047 14.1 0.0 0.12 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CCC66989.1 - 0.047 14.0 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CCC66989.1 - 0.063 13.2 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 CCC66989.1 - 0.082 12.8 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase Sigma54_activat PF00158.26 CCC66989.1 - 0.099 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain TPP_enzyme_N PF02776.18 CCC66990.1 - 4.1e-55 186.0 0.1 4.8e-54 182.6 0.0 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CCC66990.1 - 2.7e-51 173.4 0.0 9.7e-49 165.1 0.0 3.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCC66990.1 - 3.5e-39 133.7 0.4 1e-38 132.2 0.3 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain His_Phos_1 PF00300.22 CCC66991.1 - 3.5e-10 39.9 0.3 4e-05 23.4 0.0 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) SPG4 PF17325.2 CCC66992.1 - 2.1e-41 141.4 0.6 2.3e-41 141.3 0.6 1.0 1 0 0 1 1 1 1 Stationary phase protein 4 PGM_PMM_I PF02878.16 CCC66993.1 - 3.5e-35 120.7 0.6 1.2e-34 119.0 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CCC66993.1 - 2.5e-26 92.1 0.0 4.9e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CCC66993.1 - 7.4e-12 45.8 0.0 1.7e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CCC66993.1 - 5.5e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.25 CCC66994.1 - 1.6e-68 231.0 0.0 2.6e-68 230.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC66994.1 - 1.3e-30 106.6 0.0 1.9e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CCC66994.1 - 1.6e-11 44.7 0.7 1.6e-11 44.7 0.7 2.3 2 1 0 2 2 2 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CCC66994.1 - 0.00049 19.1 0.0 0.00049 19.1 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 CCC66994.1 - 0.013 15.1 0.1 2 8.0 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CCC66994.1 - 0.059 12.7 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCC66994.1 - 0.077 12.3 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 Kinase-like RRN3 PF05327.11 CCC66995.1 - 4.8e-187 622.9 9.9 5.5e-187 622.7 9.9 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 CCC66995.1 - 0.053 11.8 2.4 0.074 11.3 2.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF1539 PF07560.11 CCC66995.1 - 0.47 10.5 5.2 2 8.5 2.3 3.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) SDA1 PF05285.12 CCC66995.1 - 1.3 8.4 9.9 1.9 7.8 9.9 1.2 1 0 0 1 1 1 0 SDA1 DUF4404 PF14357.6 CCC66995.1 - 2.3 8.9 8.3 2.6 8.8 5.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) SPRY PF00622.28 CCC66996.1 - 8.1e-12 45.3 0.0 1.9e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 SPRY domain PRP9_N PF16958.5 CCC66996.1 - 0.011 15.7 2.9 0.023 14.7 2.9 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor PRP9 N-terminus SRP9-21 PF05486.12 CCC66997.1 - 2e-20 73.0 0.6 2e-20 73.0 0.6 2.8 3 1 0 3 3 3 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.32 CCC66998.1 - 1.8e-19 69.7 4.6 3.8e-05 24.4 0.1 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC66998.1 - 2.7e-08 34.0 0.1 0.42 11.0 0.0 4.6 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCC66998.1 - 0.018 14.0 0.0 0.35 9.8 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Mito_carr PF00153.27 CCC66999.1 - 3.4e-56 187.2 4.3 2.2e-18 65.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Vma12 PF11712.8 CCC67000.1 - 2.6e-38 131.2 1.0 3.5e-38 130.8 1.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Renin_r PF07850.14 CCC67000.1 - 2.7 8.6 5.6 0.48 11.1 0.8 2.2 1 1 2 3 3 3 0 Renin receptor-like protein LpxK PF02606.14 CCC67001.1 - 0.11 11.5 0.3 0.17 10.9 0.3 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase Pkinase PF00069.25 CCC67002.1 - 1.1e-39 136.4 0.0 1.7e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67002.1 - 1.3e-20 73.8 0.0 8.7e-20 71.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC67002.1 - 0.00096 18.6 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like LIN37 PF15306.6 CCC67002.1 - 0.28 11.4 4.3 0.39 10.9 0.0 2.3 1 1 0 2 2 2 0 LIN37 AP_endonuc_2 PF01261.24 CCC67003.1 - 5.2e-32 111.0 0.0 8.6e-32 110.3 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel UTP15_C PF09384.10 CCC67003.1 - 0.17 11.6 1.2 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 UTP15 C terminal Glyco_hydro_16 PF00722.21 CCC67004.1 - 3.2e-19 69.1 2.3 6.7e-19 68.0 2.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 BAF1_ABF1 PF04684.13 CCC67005.1 - 2.4e-79 267.9 30.3 6.6e-40 137.7 15.9 3.1 1 1 2 3 3 3 3 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.15 CCC67005.1 - 0.00017 21.5 1.1 0.00041 20.3 1.1 1.6 1 0 0 1 1 1 1 MuDR family transposase SLY PF12485.8 CCC67005.1 - 0.11 13.3 8.2 0.29 11.9 8.2 1.8 1 1 0 1 1 1 0 Lymphocyte signaling adaptor protein KTI12 PF08433.10 CCC67006.1 - 2.6e-91 305.8 0.6 3.1e-91 305.6 0.6 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 CCC67006.1 - 0.00014 22.4 0.0 0.00035 21.1 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCC67006.1 - 0.00077 19.7 0.0 0.0039 17.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 CCC67006.1 - 0.0013 18.6 0.0 0.0033 17.3 0.0 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 CCC67006.1 - 0.0014 18.8 0.0 0.0037 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CCC67006.1 - 0.0017 18.8 0.0 0.0044 17.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CPT PF07931.12 CCC67006.1 - 0.0018 18.1 0.0 0.0039 17.1 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_16 PF13191.6 CCC67006.1 - 0.0023 18.4 0.0 0.0065 16.9 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.6 CCC67006.1 - 0.0051 17.2 0.1 0.09 13.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CCC67006.1 - 0.0066 16.5 0.0 0.068 13.3 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase TsaE PF02367.17 CCC67006.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CCC67006.1 - 0.014 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SRPRB PF09439.10 CCC67006.1 - 0.017 14.6 0.1 0.036 13.5 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 CCC67006.1 - 0.017 15.3 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CCC67006.1 - 0.062 13.2 0.1 0.46 10.4 0.0 2.1 1 1 1 2 2 2 0 NTPase NACHT PF05729.12 CCC67006.1 - 0.089 12.7 0.1 0.34 10.8 0.0 2.1 2 1 0 2 2 2 0 NACHT domain RuvB_N PF05496.12 CCC67006.1 - 0.097 12.4 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Hap4_Hap_bind PF10297.9 CCC67007.1 - 8.6e-06 25.7 5.1 2.1e-05 24.5 5.1 1.6 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 DUF3915 PF13054.6 CCC67007.1 - 1.1 9.2 10.9 0.36 10.8 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Drc1-Sld2 PF11719.8 CCC67008.1 - 2.3e-41 142.8 38.3 1e-20 74.7 3.9 2.6 1 1 1 2 2 2 2 DNA replication and checkpoint protein DUF131 PF01998.17 CCC67008.1 - 0.19 11.4 0.0 0.74 9.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF131 E7 PF00527.18 CCC67008.1 - 2.5 8.4 5.6 2.1 8.6 1.4 2.5 2 0 0 2 2 2 0 E7 protein, Early protein DUF2115 PF09888.9 CCC67008.1 - 4 7.9 7.8 20 5.6 0.3 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) NAD_binding_10 PF13460.6 CCC67009.1 - 8.7e-33 113.7 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 CCC67009.1 - 1.7e-06 27.2 0.8 2.5e-06 26.7 0.8 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 CCC67009.1 - 0.00065 19.3 0.0 0.022 14.3 0.0 2.9 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 CCC67009.1 - 0.0046 16.4 0.0 0.01 15.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GAIN_A PF18619.1 CCC67009.1 - 0.096 12.9 0.4 1.8 8.8 0.0 2.3 2 0 0 2 2 2 0 GPCR-Autoproteolysis-INducing (GAIN) subdomain A DapB_N PF01113.20 CCC67009.1 - 0.13 12.4 0.1 0.21 11.7 0.1 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus cobW PF02492.19 CCC67010.1 - 5.4e-45 153.1 0.1 9.3e-45 152.4 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 CCC67010.1 - 0.00043 20.2 0.0 0.00076 19.4 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_29 PF13555.6 CCC67010.1 - 0.0019 17.9 0.3 0.013 15.2 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CCC67010.1 - 0.0022 18.5 1.1 0.011 16.3 0.4 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCC67010.1 - 0.0046 17.3 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CCC67010.1 - 0.011 16.2 0.0 0.036 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CCC67010.1 - 0.018 15.6 0.1 0.046 14.2 0.1 1.7 1 0 0 1 1 1 0 ABC transporter RE_NgoFVII PF09565.10 CCC67010.1 - 0.03 13.6 0.3 5.6 6.2 0.1 2.2 2 0 0 2 2 2 0 NgoFVII restriction endonuclease AAA_22 PF13401.6 CCC67010.1 - 0.042 14.1 0.0 0.49 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CCC67010.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 CCC67010.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 CCC67010.1 - 0.074 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CCC67010.1 - 0.13 12.3 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 CCC67010.1 - 0.14 12.0 0.7 1.4 8.8 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase SH3_10 PF17902.1 CCC67010.1 - 0.16 12.1 0.2 0.94 9.6 0.2 2.3 2 0 0 2 2 2 0 SH3 domain MeaB PF03308.16 CCC67010.1 - 0.48 9.3 2.1 1.5 7.8 0.0 2.5 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Phos_pyr_kin PF08543.12 CCC67011.1 - 4.6e-12 45.8 0.0 6.3e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CCC67011.1 - 0.039 13.2 0.0 0.059 12.7 0.0 1.3 1 0 0 1 1 1 0 pfkB family carbohydrate kinase RAG1 PF12940.7 CCC67011.1 - 0.091 10.8 0.0 0.14 10.3 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase ANAPC4_WD40 PF12894.7 CCC67012.1 - 2.1e-07 31.1 0.0 0.0083 16.4 0.0 3.0 2 1 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCC67012.1 - 2.7e-05 24.8 2.7 6.2 7.9 0.1 5.2 6 0 0 6 6 6 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 CCC67012.1 - 0.0071 15.4 0.8 0.18 10.8 0.1 2.3 1 1 1 2 2 2 2 Coatomer WD associated region MPP6 PF10175.9 CCC67013.1 - 3.2e-24 85.9 23.8 3.8e-24 85.7 23.8 1.1 1 0 0 1 1 1 1 M-phase phosphoprotein 6 Ribosomal_L9_N PF01281.19 CCC67014.1 - 1.6e-05 24.3 0.1 5.4e-05 22.7 0.1 2.0 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Peptidase_M76 PF09768.9 CCC67015.1 - 7.9e-71 237.3 1.0 9.8e-71 237.0 1.0 1.1 1 0 0 1 1 1 1 Peptidase M76 family Tox-MPTase2 PF15638.6 CCC67015.1 - 0.094 12.5 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 MBOAT PF03062.19 CCC67016.1 - 1.5e-76 258.0 40.0 1.9e-76 257.7 40.0 1.1 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 CCC67016.1 - 0.0021 18.3 3.8 0.009 16.3 3.8 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family HIG_1_N PF04588.13 CCC67017.1 - 1.7e-05 24.9 0.4 1.7e-05 24.9 0.4 1.7 2 0 0 2 2 2 1 Hypoxia induced protein conserved region CCB2_CCB4 PF11152.8 CCC67017.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 Tim17 PF02466.19 CCC67018.1 - 1.2e-26 93.2 2.1 1.6e-26 92.8 2.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4667 PF15700.5 CCC67019.1 - 5.9e-58 196.8 24.6 7.2e-58 196.5 24.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) Dus PF01207.17 CCC67020.1 - 4.4e-52 177.1 0.0 1.1e-51 175.8 0.0 1.6 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) HTH_34 PF13601.6 CCC67020.1 - 0.037 14.2 0.1 3.4 7.9 0.1 2.8 2 1 0 2 2 2 0 Winged helix DNA-binding domain SPX PF03105.19 CCC67021.1 - 5.8e-44 151.6 9.2 6.6e-28 98.7 2.8 2.4 1 1 1 2 2 2 2 SPX domain CitMHS PF03600.16 CCC67021.1 - 2.9e-27 95.6 71.5 8.3e-25 87.6 42.2 1.9 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 CCC67021.1 - 4.4e-24 85.4 41.3 6.2e-24 84.9 41.3 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region PRK PF00485.18 CCC67022.1 - 8.3e-66 221.5 0.0 1.6e-65 220.6 0.0 1.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.6 CCC67022.1 - 2.6e-36 125.0 0.1 3.9e-36 124.5 0.1 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_18 PF13238.6 CCC67022.1 - 4.5e-05 24.0 0.0 0.00016 22.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain CPT PF07931.12 CCC67022.1 - 0.0015 18.4 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 CCC67022.1 - 0.0047 16.2 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 CCC67022.1 - 0.0067 16.8 0.0 5.3 7.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 CCC67022.1 - 0.085 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain CoaE PF01121.20 CCC67022.1 - 0.12 12.1 1.8 8.5 6.0 0.5 3.1 3 0 0 3 3 3 0 Dephospho-CoA kinase Cytidylate_kin PF02224.18 CCC67022.1 - 0.35 10.6 2.0 19 4.9 0.3 2.3 2 0 0 2 2 2 0 Cytidylate kinase HA2 PF04408.23 CCC67023.1 - 7e-17 61.7 0.0 2.4e-16 59.9 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCC67023.1 - 3.5e-15 56.3 0.1 2.6e-14 53.5 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CCC67023.1 - 4e-13 49.5 0.0 1.2e-12 48.0 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 CCC67023.1 - 1.1e-09 38.3 0.2 2.7e-09 37.1 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCC67023.1 - 9.8e-05 22.7 0.0 0.00032 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCC67023.1 - 0.00076 19.8 0.1 0.0016 18.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCC67023.1 - 0.00088 19.0 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CCC67023.1 - 0.0018 18.3 0.9 0.21 11.6 0.3 3.7 2 1 0 2 2 2 1 AAA domain T2SSE PF00437.20 CCC67023.1 - 0.0052 15.9 0.1 0.015 14.3 0.0 1.8 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.27 CCC67023.1 - 0.0065 17.0 4.2 0.0066 17.0 0.1 2.9 3 1 0 3 3 3 1 ABC transporter ATPase PF06745.13 CCC67023.1 - 0.012 15.0 0.0 0.028 13.7 0.0 1.6 1 0 0 1 1 1 0 KaiC Flavi_DEAD PF07652.14 CCC67023.1 - 0.019 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain NB-ARC PF00931.22 CCC67023.1 - 0.034 13.3 0.0 0.076 12.2 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain Helicase_RecD PF05127.14 CCC67023.1 - 0.095 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Helicase AAA_29 PF13555.6 CCC67023.1 - 0.16 11.8 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 CCC67023.1 - 0.51 10.3 3.9 0.71 9.8 0.2 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Glyoxalase PF00903.25 CCC67024.1 - 3.3e-35 121.1 0.1 6.9e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 CCC67024.1 - 6.3e-09 36.1 0.0 0.0026 18.0 0.0 3.6 1 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 CCC67024.1 - 0.00013 22.7 0.0 0.59 10.9 0.0 2.8 2 2 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.6 CCC67024.1 - 0.0002 21.4 0.2 0.4 10.8 0.0 2.5 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_2 PF12681.7 CCC67024.1 - 0.0081 16.1 1.4 38 4.2 0.0 4.5 4 1 1 5 5 5 0 Glyoxalase-like domain Med9 PF07544.13 CCC67025.1 - 7.3e-24 83.7 0.5 7.3e-24 83.7 0.5 1.8 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 TBCA PF02970.16 CCC67025.1 - 0.026 14.8 1.5 0.047 14.0 0.4 1.9 2 0 0 2 2 2 0 Tubulin binding cofactor A UPF0242 PF06785.11 CCC67025.1 - 0.041 14.0 2.8 0.073 13.2 2.8 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-RING_2 PF13639.6 CCC67026.1 - 6.9e-11 42.3 11.8 6.9e-11 42.3 11.8 1.7 1 1 1 2 2 2 2 Ring finger domain zf-rbx1 PF12678.7 CCC67026.1 - 5.9e-09 36.1 13.4 2.7e-08 34.0 13.4 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CCC67026.1 - 6.2e-05 22.8 16.2 7.1e-05 22.6 14.0 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 CCC67026.1 - 7.8e-05 22.7 7.7 0.00074 19.5 7.8 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CCC67026.1 - 0.00025 20.9 9.6 0.00025 20.9 9.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCC67026.1 - 0.0017 18.0 10.0 0.0017 18.0 10.0 1.9 2 0 0 2 2 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CCC67026.1 - 0.0023 17.9 6.0 0.0023 17.9 6.0 1.8 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CCC67026.1 - 0.0062 16.4 12.2 0.09 12.6 10.6 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CCC67026.1 - 0.0073 16.5 8.2 0.023 14.9 7.7 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_5 PF14634.6 CCC67026.1 - 0.0092 15.9 12.2 0.017 15.1 10.5 2.1 1 1 1 2 2 2 2 zinc-RING finger domain PHD PF00628.29 CCC67026.1 - 0.063 13.2 7.5 0.13 12.2 7.5 1.6 1 0 0 1 1 1 0 PHD-finger Zn_ribbon_17 PF17120.5 CCC67026.1 - 0.076 12.7 7.8 0.14 11.8 7.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 CCC67026.1 - 0.22 11.2 10.1 1.1 9.0 4.0 2.3 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.6 CCC67026.1 - 0.36 10.7 9.3 1.5 8.7 2.2 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 CCC67026.1 - 0.42 10.5 15.4 2.1 8.3 1.1 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.7 CCC67026.1 - 3.4 7.9 8.6 2.7 8.2 6.9 1.8 1 1 0 1 1 1 0 RING-variant domain Whi5 PF08528.11 CCC67027.1 - 6.2e-09 35.3 1.2 1.4e-08 34.2 1.2 1.7 1 0 0 1 1 1 1 Whi5 like PID_2 PF14719.6 CCC67027.1 - 0.00088 19.2 0.9 0.0016 18.4 0.9 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DNA_primase_lrg PF04104.14 CCC67028.1 - 1.1e-92 310.3 0.3 1.6e-92 309.7 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit KilA-N PF04383.13 CCC67029.1 - 9.1e-05 22.3 0.1 0.0011 18.7 0.0 2.6 2 1 0 2 2 2 1 KilA-N domain Spc42p PF11544.8 CCC67030.1 - 1.5e-10 40.9 9.4 1.5e-10 40.9 9.4 3.6 2 2 1 4 4 4 1 Spindle pole body component Spc42p ATG16 PF08614.11 CCC67030.1 - 0.0043 17.3 10.7 0.0043 17.3 10.7 2.3 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) DivIVA PF05103.13 CCC67030.1 - 0.036 14.2 6.9 0.052 13.6 1.1 2.6 2 1 0 2 2 2 0 DivIVA protein Snf7 PF03357.21 CCC67031.1 - 4.8e-33 114.2 18.2 4.8e-33 114.2 18.2 1.9 2 0 0 2 2 2 1 Snf7 Eno-Rase_FAD_bd PF07055.12 CCC67031.1 - 0.021 15.2 1.6 0.021 15.2 1.6 2.6 2 1 1 3 3 3 0 Enoyl reductase FAD binding domain PAS_7 PF12860.7 CCC67031.1 - 0.042 14.0 6.3 2.7 8.2 0.1 3.6 2 1 2 4 4 4 0 PAS fold Lyase_8_N PF08124.11 CCC67031.1 - 0.33 9.8 8.3 0.032 13.2 3.4 1.7 2 1 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain DUF1574 PF07611.11 CCC67031.1 - 0.42 9.9 9.5 1.5 8.1 9.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1574) RPW8 PF05659.11 CCC67031.1 - 6.6 6.4 13.1 0.28 10.9 5.3 2.4 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Lung_7-TM_R PF06814.13 CCC67032.1 - 1e-85 287.6 23.9 1.4e-85 287.2 23.9 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor YajC PF02699.15 CCC67032.1 - 2.5 8.1 5.4 1 9.3 0.7 2.6 2 0 0 2 2 2 0 Preprotein translocase subunit Zn_clus PF00172.18 CCC67033.1 - 4.1e-10 39.6 12.4 6.6e-10 38.9 12.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-rbx1 PF12678.7 CCC67034.1 - 1.2e-08 35.1 5.5 2.1e-08 34.3 5.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CCC67034.1 - 1.4e-08 34.9 7.5 3.6e-08 33.6 7.5 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CCC67034.1 - 5.2e-07 29.5 3.8 8.6e-07 28.8 3.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 CCC67034.1 - 2.4e-06 27.3 2.5 2.4e-06 27.3 2.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCC67034.1 - 4.7e-05 23.2 2.8 0.00011 22.0 2.9 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CCC67034.1 - 6.1e-05 22.8 6.0 0.00012 21.9 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC67034.1 - 0.00015 21.7 3.9 0.00036 20.5 3.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 CCC67034.1 - 0.00032 20.4 7.9 0.0076 16.0 1.9 2.7 2 0 0 2 2 2 2 RING-like zinc finger zf-ANAPC11 PF12861.7 CCC67034.1 - 0.00095 19.2 1.8 0.002 18.1 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CCC67034.1 - 0.0019 18.0 4.9 0.0072 16.2 4.9 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CCC67034.1 - 0.0021 17.7 2.9 0.0021 17.7 2.9 1.8 2 0 0 2 2 1 1 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 CCC67034.1 - 0.014 15.3 0.2 0.032 14.1 0.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FANCL_C PF11793.8 CCC67034.1 - 0.13 12.5 5.1 0.4 10.9 5.1 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 CCC67034.1 - 0.15 12.1 1.5 0.41 10.7 1.5 1.7 1 0 0 1 1 1 0 Zinc-finger RINGv PF12906.7 CCC67034.1 - 4.1 7.6 5.4 13 6.0 5.4 1.9 1 1 0 1 1 1 0 RING-variant domain zf-P11 PF03854.14 CCC67034.1 - 4.7 6.9 5.2 1.5 8.5 2.1 1.8 2 0 0 2 2 2 0 P-11 zinc finger HAD_2 PF13419.6 CCC67035.1 - 2.5e-19 70.0 0.0 3.2e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCC67035.1 - 7.5e-10 39.4 0.0 8.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CCC67035.1 - 0.017 15.6 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 CCC67035.1 - 0.018 15.2 0.0 0.031 14.4 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase CDC45 PF02724.14 CCC67036.1 - 8.6 4.5 8.7 13 3.9 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein HMG_box PF00505.19 CCC67037.1 - 2.6e-35 120.6 9.6 1.2e-18 67.3 1.9 3.0 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CCC67037.1 - 9.6e-16 58.2 5.2 4e-10 40.1 1.0 3.9 4 1 1 5 5 5 2 HMG-box domain CHDNT PF08073.12 CCC67037.1 - 2.1e-11 43.6 0.0 9.4e-06 25.5 0.0 2.8 2 0 0 2 2 2 2 CHDNT (NUC034) domain zf-C2H2 PF00096.26 CCC67038.1 - 0.00046 20.5 15.9 0.00068 19.9 4.9 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_aberr PF17017.5 CCC67038.1 - 0.0014 18.8 2.5 0.0025 18.0 2.5 1.3 1 0 0 1 1 1 1 Aberrant zinc-finger Lipase_C PF18067.1 CCC67038.1 - 0.051 14.1 2.0 7.3 7.2 0.0 3.0 4 0 0 4 4 4 0 Lipase C-terminal domain PyrI_C PF02748.15 CCC67038.1 - 0.11 12.4 0.4 0.55 10.2 0.1 2.1 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_4 PF13894.6 CCC67038.1 - 0.12 13.2 19.8 0.068 14.0 5.1 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 CCC67038.1 - 0.34 11.2 7.3 0.72 10.2 7.3 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Malic_M PF03949.15 CCC67039.1 - 4.1e-84 281.9 0.0 5.6e-84 281.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 CCC67039.1 - 2.8e-64 216.3 0.0 5.4e-64 215.3 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.20 CCC67039.1 - 0.2 11.7 0.4 4 7.5 0.0 3.0 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase TFIIE_alpha PF02002.17 CCC67040.1 - 1.1e-34 118.5 0.0 1.1e-34 118.5 0.0 2.4 3 0 0 3 3 3 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.12 CCC67040.1 - 1.7e-11 43.5 0.5 4.9e-11 42.0 0.5 1.9 1 0 0 1 1 1 1 TFIIB zinc-binding ThiF PF00899.21 CCC67041.1 - 4.2e-44 150.8 0.0 6.2e-44 150.2 0.0 1.1 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CCC67041.1 - 0.00036 20.6 0.1 0.00075 19.6 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 CCC67041.1 - 0.0017 18.6 1.0 0.0082 16.4 1.0 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CCC67041.1 - 0.0075 16.5 0.9 0.015 15.5 0.0 2.0 3 0 0 3 3 3 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 CCC67041.1 - 0.029 13.9 0.3 0.058 13.0 0.3 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.16 CCC67041.1 - 0.079 12.6 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Mito_carr PF00153.27 CCC67042.1 - 1.9e-59 197.6 2.8 5.7e-21 74.2 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCC67042.1 - 0.065 12.4 2.8 3.4 6.7 0.0 3.0 2 1 0 3 3 3 0 Gammaproteobacterial serine protease Tim17 PF02466.19 CCC67042.1 - 0.81 10.1 4.6 15 6.0 0.0 3.3 1 1 1 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family DUF2370 PF10176.9 CCC67043.1 - 6.6e-84 281.1 0.5 1.3e-83 280.1 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) SNF5 PF04855.12 CCC67044.1 - 1.4e-49 169.1 1.6 2.3e-35 122.5 0.0 4.3 3 1 1 4 4 4 2 SNF5 / SMARCB1 / INI1 DUF4186 PF13811.6 CCC67044.1 - 0.092 12.8 0.7 0.39 10.8 0.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4186) Adap_comp_sub PF00928.21 CCC67045.1 - 1.3e-32 113.2 0.0 9.8e-32 110.4 0.0 1.9 1 1 0 1 1 1 1 Adaptor complexes medium subunit family adh_short PF00106.25 CCC67046.1 - 7e-86 286.7 10.5 6.5e-44 149.7 1.0 2.7 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CCC67046.1 - 6.7e-68 228.7 5.8 1.5e-36 126.1 0.3 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MaoC_dehydratas PF01575.19 CCC67046.1 - 1e-32 112.3 0.0 2.1e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain KR PF08659.10 CCC67046.1 - 2.4e-32 112.3 3.9 1e-15 58.1 0.4 2.6 2 1 0 2 2 2 2 KR domain MaoC_dehydrat_N PF13452.6 CCC67046.1 - 0.00076 19.6 0.0 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 2-Hacid_dh_C PF02826.19 CCC67046.1 - 0.025 13.9 0.0 0.071 12.5 0.0 1.7 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF460 PF04312.13 CCC67046.1 - 0.087 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF460) 3HCDH_N PF02737.18 CCC67046.1 - 0.31 10.9 2.1 7.6 6.4 0.0 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PglL_A PF15864.5 CCC67046.1 - 5.2 6.9 12.3 5.6 6.8 1.0 3.6 3 0 0 3 3 3 0 Protein glycosylation ligase QCR10 PF09796.9 CCC67047.1 - 8.4e-26 89.8 0.1 9.8e-26 89.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Bromodomain PF00439.25 CCC67048.1 - 3.8e-30 103.8 3.8 4.7e-19 68.3 0.1 3.0 3 0 0 3 3 3 2 Bromodomain AAA_12 PF13087.6 CCC67048.1 - 0.24 11.0 2.3 1.8 8.1 0.4 2.4 2 0 0 2 2 2 0 AAA domain LAMTOR PF15454.6 CCC67049.1 - 1.7e-16 60.6 0.6 1.7e-16 60.6 0.6 2.7 2 1 1 3 3 3 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF655 PF04919.12 CCC67049.1 - 0.097 12.6 0.7 0.13 12.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF655) Ribosomal_L50 PF10501.9 CCC67050.1 - 5.7e-23 81.2 1.3 1.5e-22 79.8 0.3 2.0 2 0 0 2 2 2 1 Ribosomal subunit 39S KilA-N PF04383.13 CCC67050.1 - 0.033 14.0 0.2 0.033 14.0 0.2 1.8 2 0 0 2 2 2 0 KilA-N domain V1R PF03402.14 CCC67051.1 - 0.59 9.7 4.5 0.1 12.2 0.8 1.6 2 0 0 2 2 2 0 Vomeronasal organ pheromone receptor family, V1R CFEM PF05730.11 CCC67051.1 - 1.7 8.8 9.8 4.5 7.4 9.8 1.7 1 1 0 1 1 1 0 CFEM domain PPTA PF01239.22 CCC67052.1 - 0.16 11.7 4.5 0.064 13.0 1.0 2.4 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat Oxysterol_BP PF01237.18 CCC67053.1 - 1.5e-83 280.7 0.3 9.8e-82 274.7 0.3 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein BNIP2 PF12496.8 CCC67053.1 - 1.2 9.5 4.5 14 6.2 0.7 2.4 2 0 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 PAP_central PF04928.17 CCC67054.1 - 2.8e-110 367.2 0.0 7e-110 365.8 0.0 1.7 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 CCC67054.1 - 1.7e-52 177.5 4.2 3.3e-52 176.6 4.2 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 CCC67054.1 - 3.9e-14 52.7 0.0 1.6e-13 50.8 0.0 2.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 CCC67054.1 - 0.033 14.3 0.3 0.14 12.2 0.0 2.2 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase DUF2420 PF10336.9 CCC67054.1 - 0.058 13.4 0.0 1 9.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2420) Dynamin_M PF01031.20 CCC67055.1 - 6.4e-103 343.9 0.5 1.4e-102 342.8 0.1 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 CCC67055.1 - 3.6e-56 189.8 0.1 1.3e-55 188.0 0.0 2.1 2 1 0 2 2 2 1 Dynamin family GED PF02212.18 CCC67055.1 - 1.7e-26 92.2 2.4 4.2e-26 90.9 2.4 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 CCC67055.1 - 0.00081 19.5 1.7 0.0037 17.3 1.7 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase CD99L2 PF12301.8 CCC67055.1 - 0.016 15.5 0.7 0.036 14.4 0.7 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 PSD4 PF07631.11 CCC67055.1 - 0.085 13.4 0.4 0.41 11.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1592) AAA_16 PF13191.6 CCC67055.1 - 0.11 12.9 0.0 0.38 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 CCC67056.1 - 2.2e-75 251.9 0.0 2.7e-75 251.6 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.6 CCC67056.1 - 2.8e-07 30.8 0.0 7.9e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.10 CCC67056.1 - 0.00034 20.2 0.0 0.00037 20.0 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.6 CCC67056.1 - 0.0018 18.0 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CCC67056.1 - 0.0086 16.6 0.0 0.014 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 CCC67056.1 - 0.023 14.8 0.0 0.032 14.3 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain G-alpha PF00503.20 CCC67056.1 - 0.089 11.9 0.1 0.21 10.7 0.1 1.5 1 1 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 CCC67056.1 - 0.091 13.3 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CCC67056.1 - 0.099 13.0 0.1 0.1 13.0 0.1 1.3 1 1 0 1 1 1 0 AAA ATPase domain CPT PF07931.12 CCC67056.1 - 0.24 11.2 0.3 3.7 7.4 0.0 2.3 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Snf7 PF03357.21 CCC67057.1 - 2.9e-31 108.4 26.5 9.2e-31 106.8 24.8 1.9 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.14 CCC67057.1 - 4.7e-06 26.6 9.0 6.7e-06 26.1 9.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Hpt PF01627.23 CCC67057.1 - 0.026 14.8 0.8 0.026 14.8 0.8 2.2 2 0 0 2 2 2 0 Hpt domain YlqD PF11068.8 CCC67057.1 - 3.1 8.2 22.9 1.5 9.2 14.7 2.4 1 1 1 2 2 2 0 YlqD protein DUF87 PF01935.17 CCC67057.1 - 4.2 7.4 10.7 3.7 7.6 0.2 2.1 1 1 1 2 2 2 0 Helicase HerA, central domain DUF1002 PF06207.11 CCC67057.1 - 6.1 6.3 14.9 0.96 8.9 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1002) PITH PF06201.13 CCC67058.1 - 1.7e-34 119.3 0.0 2.3e-34 118.8 0.0 1.2 1 0 0 1 1 1 1 PITH domain YodL PF14191.6 CCC67058.1 - 0.12 13.3 0.0 0.25 12.2 0.0 1.6 1 0 0 1 1 1 0 YodL-like bZIP_1 PF00170.21 CCC67060.1 - 1.3e-05 25.2 18.6 2.7e-05 24.2 18.6 1.6 1 0 0 1 1 1 1 bZIP transcription factor DUF5094 PF17015.5 CCC67060.1 - 0.0054 16.9 12.7 0.0088 16.2 12.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5094) Macoilin PF09726.9 CCC67060.1 - 0.077 11.5 11.0 0.088 11.4 11.0 1.1 1 0 0 1 1 1 0 Macoilin family Glutaredoxin2_C PF04399.13 CCC67060.1 - 0.46 10.3 3.8 1 9.2 3.8 1.6 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain SOBP PF15279.6 CCC67060.1 - 2.1 8.9 11.0 2.7 8.5 11.0 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein MAS20 PF02064.15 CCC67060.1 - 3.6 7.7 8.1 6 7.0 8.1 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor CUE PF02845.16 CCC67061.1 - 1.4e-11 43.8 1.4 2e-06 27.4 0.3 3.5 3 0 0 3 3 3 2 CUE domain Smr PF01713.21 CCC67061.1 - 0.0087 16.4 0.0 0.017 15.4 0.0 1.5 1 0 0 1 1 1 1 Smr domain CENP-C_C PF11699.8 CCC67062.1 - 2.2e-28 98.3 3.5 4.5e-28 97.3 3.5 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.6 CCC67062.1 - 1.2e-06 29.2 1.7 1.2e-06 29.2 1.7 3.1 3 2 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 CCC67062.1 - 7.1e-05 22.4 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Pkinase PF00069.25 CCC67063.1 - 1.2e-71 241.2 0.0 1.9e-71 240.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67063.1 - 1.4e-46 158.9 0.0 2.5e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CCC67063.1 - 2e-22 79.3 2.8 6.3e-22 77.7 0.1 3.0 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.6 CCC67063.1 - 5.8e-05 22.5 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCC67063.1 - 0.00015 20.7 0.0 0.00015 20.7 0.0 2.8 2 1 1 3 3 3 1 Fungal protein kinase HECT PF00632.25 CCC67064.1 - 4.7e-74 249.6 0.2 9e-74 248.7 0.2 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) EF-hand_9 PF14658.6 CCC67064.1 - 0.08 13.3 0.0 0.31 11.4 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain Fes1 PF08609.10 CCC67064.1 - 0.48 11.3 4.8 15 6.6 2.1 3.1 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Sigma70_ner PF04546.13 CCC67064.1 - 1.5 8.6 10.3 0.32 10.9 4.4 2.6 3 0 0 3 3 3 0 Sigma-70, non-essential region TRAM_LAG1_CLN8 PF03798.16 CCC67065.1 - 2.5e-38 131.8 25.2 2.5e-38 131.8 25.2 2.2 2 0 0 2 2 2 2 TLC domain TRAM1 PF08390.11 CCC67065.1 - 5.5e-20 70.8 1.0 1.9e-19 69.1 1.0 2.0 1 0 0 1 1 1 1 TRAM1-like protein HIF-1 PF11413.8 CCC67065.1 - 0.13 11.7 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 VHS PF00790.19 CCC67066.1 - 1.1e-33 116.0 3.8 1.1e-33 116.0 3.8 2.1 3 0 0 3 3 3 1 VHS domain SH3_1 PF00018.28 CCC67066.1 - 5.9e-14 51.4 0.0 1.2e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCC67066.1 - 6.3e-14 51.6 0.1 1e-13 50.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCC67066.1 - 1.5e-10 40.6 0.0 7.2e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain GAT PF03127.14 CCC67066.1 - 5e-07 29.9 0.8 2.2e-05 24.7 0.0 3.1 2 1 0 2 2 2 1 GAT domain DUF5067 PF16729.5 CCC67066.1 - 0.0031 17.4 0.4 0.0095 15.9 0.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5067) IFT57 PF10498.9 CCC67066.1 - 0.0036 16.3 8.1 0.0067 15.4 8.1 1.5 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 V_ATPase_I PF01496.19 CCC67066.1 - 0.011 13.7 1.3 0.015 13.3 1.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DltD PF04914.12 CCC67066.1 - 0.062 12.7 5.8 0.14 11.5 5.8 1.6 1 0 0 1 1 1 0 DltD protein ALMT PF11744.8 CCC67066.1 - 0.1 11.4 3.9 0.18 10.6 3.9 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter FliE PF02049.18 CCC67066.1 - 0.37 11.0 4.0 7.2 6.8 1.8 3.2 3 0 0 3 3 3 0 Flagellar hook-basal body complex protein FliE Suf PF05843.14 CCC67066.1 - 4.6 7.1 14.0 0.094 12.7 3.2 2.6 2 1 0 2 2 2 0 Suppressor of forked protein (Suf) SNF2_N PF00176.23 CCC67069.1 - 5.4e-57 193.1 0.0 8.5e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.10 CCC67069.1 - 6.7e-49 166.5 4.1 3.2e-48 164.3 3.8 2.1 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.31 CCC67069.1 - 7.3e-17 61.7 0.0 2.1e-16 60.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC67069.1 - 6.9e-07 29.4 0.0 2e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CCC67069.1 - 8.5e-06 25.1 2.9 1.6e-05 24.2 0.1 2.8 2 1 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Ran-binding PF05508.11 CCC67070.1 - 4.4e-111 370.8 3.8 6.7e-111 370.2 3.8 1.2 1 0 0 1 1 1 1 RanGTP-binding protein VID27_N PF17748.1 CCC67070.1 - 0.018 14.9 0.6 0.018 14.9 0.6 2.5 2 0 0 2 2 2 0 VID27 N-terminal region RBD-FIP PF09457.10 CCC67070.1 - 0.073 13.0 0.0 0.21 11.5 0.0 1.8 1 0 0 1 1 1 0 FIP domain AAA_lid_9 PF17871.1 CCC67070.1 - 8.6 6.4 10.7 0.18 11.8 1.8 2.5 3 0 0 3 3 3 0 AAA lid domain Copper-fist PF00649.18 CCC67071.1 - 5.1e-20 70.7 1.9 5.1e-20 70.7 1.9 2.2 1 1 1 2 2 2 1 Copper fist DNA binding domain Cullin PF00888.22 CCC67072.1 - 1.4e-126 423.6 19.3 1.4e-126 423.6 19.3 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 CCC67072.1 - 4e-14 52.4 3.1 4.7e-14 52.2 0.5 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain Pex24p PF06398.11 CCC67073.1 - 2.2e-86 290.2 10.6 2.7e-86 289.8 10.6 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin LTXXQ PF07813.12 CCC67073.1 - 0.053 14.3 0.0 0.11 13.3 0.0 1.5 1 0 0 1 1 1 0 LTXXQ motif family protein Ribosomal_L38e PF01781.18 CCC67074.1 - 6.9e-28 96.6 3.4 7.6e-28 96.4 3.4 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family TFIIF_beta_N PF17683.1 CCC67075.1 - 4.1e-36 124.7 7.4 1.7e-35 122.7 7.4 2.1 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus TFIIF_beta PF02270.15 CCC67075.1 - 1.6e-27 95.4 0.6 3.1e-27 94.5 0.6 1.5 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain Tau95 PF09734.9 CCC67075.1 - 0.0013 19.5 0.3 0.0013 19.5 0.3 2.5 1 1 1 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Prp18 PF02840.15 CCC67076.1 - 4.5e-33 114.3 1.9 6.4e-33 113.8 0.1 1.9 1 1 0 2 2 2 1 Prp18 domain CTP_transf_like PF01467.26 CCC67077.1 - 4.6e-31 107.9 0.0 4.9e-21 75.4 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 CCC67077.1 - 5.7e-06 26.3 0.0 0.087 12.7 0.0 3.2 3 0 0 3 3 3 2 FAD synthetase N6-adenineMlase PF10237.9 CCC67078.1 - 4.5e-57 192.3 0.0 6.4e-57 191.8 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase 3Beta_HSD PF01073.19 CCC67079.1 - 9.9e-91 303.6 0.0 1.2e-90 303.3 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CCC67079.1 - 2.7e-26 92.5 0.0 3.4e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CCC67079.1 - 1.8e-12 47.3 0.0 1.6e-11 44.2 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CCC67079.1 - 3.3e-10 40.2 0.0 4.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 CCC67079.1 - 5.8e-10 38.8 0.0 3.1e-08 33.1 0.0 2.4 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 CCC67079.1 - 1.9e-09 37.0 0.0 3e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 CCC67079.1 - 5.2e-08 32.4 0.0 8.7e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 CCC67079.1 - 0.0027 17.6 0.0 0.021 14.8 0.0 2.0 1 1 0 1 1 1 1 KR domain PALP PF00291.25 CCC67080.1 - 2.4e-64 217.6 0.2 2.8e-64 217.4 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme NAM-associated PF14303.6 CCC67081.1 - 0.18 12.5 0.0 0.18 12.5 0.0 3.1 4 1 0 4 4 4 0 No apical meristem-associated C-terminal domain Abhydrolase_1 PF00561.20 CCC67082.1 - 8.3e-15 55.1 0.0 1.4e-14 54.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCC67082.1 - 9.4e-10 38.2 0.0 7.3e-09 35.2 0.0 2.1 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCC67082.1 - 5.3e-09 37.0 0.0 6.1e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CCC67082.1 - 0.00014 21.7 0.1 0.0082 15.9 0.1 2.6 2 1 0 2 2 2 1 PGAP1-like protein Thioesterase PF00975.20 CCC67082.1 - 0.00015 21.9 0.0 0.00023 21.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.25 CCC67082.1 - 0.09 12.6 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.13 CCC67082.1 - 0.16 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF3325 PF11804.8 CCC67083.1 - 0.021 15.0 0.0 0.041 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) CutA1 PF03091.15 CCC67083.1 - 0.025 14.4 0.0 0.058 13.3 0.0 1.6 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Flavi_NS4A PF01350.17 CCC67083.1 - 0.072 13.0 0.2 0.072 13.0 0.2 1.8 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A MFS_1 PF07690.16 CCC67083.1 - 1.9 7.3 6.3 1.2 8.0 0.1 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily CTP_transf_1 PF01148.20 CCC67083.1 - 3.1 7.5 8.9 6.6 6.4 7.9 1.7 1 1 1 2 2 2 0 Cytidylyltransferase family SANT_DAMP1_like PF16282.5 CCC67084.1 - 1.5e-25 89.2 4.1 1.5e-25 89.2 4.1 2.4 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 DMAP1_like PF17024.5 CCC67084.1 - 0.00025 21.2 1.4 0.00054 20.1 0.3 2.2 2 0 0 2 2 2 1 Putative DMAP1-like DMAP1 PF05499.12 CCC67084.1 - 0.015 15.2 14.6 0.12 12.3 12.7 2.7 1 1 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Iron_permease PF04120.12 CCC67085.1 - 1.4e-25 89.5 29.9 6.3e-16 58.3 1.8 5.4 6 0 0 6 6 6 5 Low affinity iron permease DUF572 PF04502.13 CCC67086.1 - 5.8e-48 164.2 19.9 1e-47 163.4 19.9 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF572) DDE_Tnp_IS1 PF03400.13 CCC67086.1 - 0.068 13.5 0.0 0.14 12.5 0.0 1.5 1 0 0 1 1 1 0 IS1 transposase zinc_ribbon_4 PF13717.6 CCC67086.1 - 0.088 12.8 0.4 0.57 10.2 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Mu-like_Com PF10122.9 CCC67086.1 - 0.12 11.8 0.5 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-FPG_IleRS PF06827.14 CCC67086.1 - 0.23 11.3 3.0 0.44 10.4 0.8 2.3 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Zn_ribbon_SprT PF17283.2 CCC67086.1 - 0.53 10.2 2.5 2 8.4 2.7 1.7 1 1 1 2 2 2 0 SprT-like zinc ribbon domain zf_UBZ PF18439.1 CCC67086.1 - 0.58 9.8 2.4 10 5.8 0.2 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger E7 PF00527.18 CCC67086.1 - 0.73 10.1 0.0 0.73 10.1 0.0 3.1 2 1 0 2 2 2 0 E7 protein, Early protein 60KD_IMP PF02096.20 CCC67086.1 - 7 6.5 7.5 1.3 8.9 3.7 1.6 2 0 0 2 2 2 0 60Kd inner membrane protein RT_RNaseH_2 PF17919.1 CCC67087.1 - 1.4e-30 105.2 0.0 4.1e-30 103.8 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCC67087.1 - 3.9e-30 104.2 0.0 7.8e-30 103.3 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CCC67087.1 - 3.7e-26 92.0 0.4 8.4e-26 90.9 0.4 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CCC67087.1 - 7.2e-16 58.0 0.1 1.5e-15 57.1 0.1 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CCC67087.1 - 8e-15 55.1 0.0 2e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Hydrolase_4 PF12146.8 CCC67090.1 - 2.4e-46 157.9 0.0 3.2e-46 157.5 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCC67090.1 - 5e-19 69.0 0.0 9.9e-18 64.7 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCC67090.1 - 1.2e-08 35.8 0.0 1.3e-08 35.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 CCC67090.1 - 0.00018 21.2 0.0 0.0054 16.3 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 CCC67090.1 - 0.0063 16.3 0.0 1.5 8.6 0.0 2.9 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 CCC67090.1 - 0.012 15.1 0.6 0.059 12.8 0.0 2.2 3 0 0 3 3 3 0 Prolyl oligopeptidase family Mlp PF03304.13 CCC67090.1 - 0.11 12.7 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Mlp lipoprotein family MBR1 PF17058.5 CCC67091.1 - 4.5e-64 216.6 9.9 4.5e-64 216.6 9.9 2.0 2 0 0 2 2 2 1 Mitochondrial biogenesis regulation protein 1 RasGAP PF00616.19 CCC67092.1 - 9.9e-40 136.5 9.7 6.1e-39 133.9 9.7 2.4 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 CCC67092.1 - 0.002 18.4 0.2 0.0056 17.0 0.2 1.8 1 0 0 1 1 1 1 C2 domain Snf7 PF03357.21 CCC67093.1 - 1.2e-33 116.1 9.8 1.6e-33 115.8 9.8 1.1 1 0 0 1 1 1 1 Snf7 Syntaxin-18_N PF10496.9 CCC67093.1 - 0.033 14.4 0.9 0.072 13.3 0.9 1.6 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus Trypan_PARP PF05887.11 CCC67093.1 - 0.05 13.6 4.6 0.078 13.0 4.6 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Mit_KHE1 PF10173.9 CCC67093.1 - 0.37 10.8 3.5 4 7.5 3.5 2.1 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Glyco_transf_22 PF03901.17 CCC67094.1 - 1.9e-28 99.9 25.4 2.3e-28 99.6 25.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1772 PF08592.11 CCC67094.1 - 0.2 11.9 2.5 0.28 11.5 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) Pkinase PF00069.25 CCC67095.1 - 1.1e-65 221.7 0.0 1.9e-65 220.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67095.1 - 3.1e-36 125.0 0.0 6.6e-27 94.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCC67095.1 - 3.9e-05 23.1 2.6 7.3e-05 22.2 0.2 2.5 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 CCC67095.1 - 0.031 14.2 0.0 0.26 11.2 0.0 2.3 2 1 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCC67095.1 - 0.12 11.1 0.0 0.12 11.1 0.0 2.4 3 0 0 3 3 3 0 Fungal protein kinase Kdo PF06293.14 CCC67095.1 - 0.14 11.5 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CRR7 PF12095.8 CCC67095.1 - 1.4 9.5 3.9 1.2 9.6 0.2 3.0 3 0 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 Macoilin PF09726.9 CCC67095.1 - 3.8 6.0 10.2 6.4 5.2 10.2 1.3 1 0 0 1 1 1 0 Macoilin family Metallophos PF00149.28 CCC67096.1 - 2.1e-34 119.8 0.3 3.1e-34 119.3 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ubiquitin PF00240.23 CCC67097.1 - 1.3e-08 34.5 0.4 1.5e-08 34.3 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCC67097.1 - 0.0002 21.1 0.4 0.00022 21.0 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCC67097.1 - 0.027 14.9 0.4 0.14 12.7 0.4 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Chorismate_bind PF00425.18 CCC67098.1 - 2.2e-69 233.9 0.0 3.1e-69 233.4 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 CCC67098.1 - 2.4e-28 99.2 0.0 3.7e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 CCC67098.1 - 3.4e-18 66.2 0.0 1.4e-17 64.2 0.0 2.1 3 0 0 3 3 3 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 CCC67098.1 - 1.6e-06 28.0 0.0 2.8e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 Glucosamine_iso PF01182.20 CCC67099.1 - 5.2e-55 186.8 0.0 8.5e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase LMBR1 PF04791.16 CCC67100.1 - 1.8e-31 109.7 29.6 3.2e-31 108.8 29.6 1.4 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF3215 PF11503.8 CCC67102.1 - 6.7e-25 86.7 0.0 8.2e-25 86.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) CobW_C PF07683.14 CCC67102.1 - 0.087 12.8 0.0 0.8 9.7 0.0 2.6 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Ribosom_S12_S23 PF00164.25 CCC67103.1 - 4.7e-26 90.6 0.3 5.3e-26 90.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S19 PF00203.21 CCC67104.1 - 7.1e-26 89.9 0.0 8.6e-26 89.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 DEAD PF00270.29 CCC67105.1 - 4.3e-43 147.1 0.8 9.9e-43 145.9 0.8 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC67105.1 - 2.6e-20 72.8 3.2 2.8e-20 72.7 0.5 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC67105.1 - 7.1e-10 39.1 1.7 9.5e-09 35.5 0.1 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 CCC67105.1 - 0.0037 17.3 0.2 0.044 13.7 0.1 2.5 1 1 1 2 2 2 1 Flavivirus DEAD domain AAA_22 PF13401.6 CCC67105.1 - 0.06 13.6 1.0 0.37 11.1 1.0 2.4 1 1 0 1 1 1 0 AAA domain PgaD PF13994.6 CCC67106.1 - 0.92 9.6 4.4 0.16 12.1 0.4 1.8 2 0 0 2 2 2 0 PgaD-like protein Cation_efflux PF01545.21 CCC67106.1 - 3.5 7.3 15.0 16 5.2 15.0 2.0 1 1 0 1 1 1 0 Cation efflux family UbiA PF01040.18 CCC67108.1 - 6e-44 150.2 16.7 7.7e-44 149.9 16.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Latrophilin PF02354.16 CCC67108.1 - 0.25 10.4 0.1 0.34 9.9 0.1 1.1 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region MDD_C PF18376.1 CCC67109.1 - 8e-69 231.1 0.1 1.2e-68 230.6 0.1 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 CCC67109.1 - 6.6e-10 39.1 2.5 1.7e-09 37.8 2.2 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF1819 PF08849.11 CCC67109.1 - 0.057 13.2 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) ARTD15_N PF18084.1 CCC67109.1 - 0.094 13.0 0.3 1.2 9.4 0.0 2.8 3 1 1 4 4 4 0 ARTD15 N-terminal domain WD40 PF00400.32 CCC67110.1 - 1.7e-51 171.0 13.0 6.8e-09 36.2 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CCC67110.1 - 3.9e-26 91.2 13.2 3.9e-26 91.2 13.2 2.0 2 0 0 2 2 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CCC67110.1 - 9.3e-18 64.3 0.0 0.00013 22.2 0.0 6.6 2 2 5 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCC67110.1 - 2.3e-05 23.3 2.7 0.69 8.5 0.0 4.2 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCC67110.1 - 0.00024 20.2 0.3 1.4 7.8 0.0 4.5 2 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein SUIM_assoc PF16619.5 CCC67110.1 - 0.00051 20.1 9.6 0.0045 17.0 0.0 3.4 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 WD40_like PF17005.5 CCC67110.1 - 0.00072 19.0 0.1 2 7.6 0.0 4.0 3 1 2 5 5 5 2 WD40-like domain RE_HindIII PF09518.10 CCC67110.1 - 0.28 10.4 5.3 0.53 9.5 5.3 1.4 1 0 0 1 1 1 0 HindIII restriction endonuclease TPR_22 PF18833.1 CCC67110.1 - 1.4 9.1 5.2 3.4 7.9 0.8 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat FapA PF03961.13 CCC67110.1 - 1.7 7.2 7.1 2.9 6.4 7.1 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF4407 PF14362.6 CCC67110.1 - 2.3 7.5 14.5 5.7 6.2 14.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 CCC67110.1 - 6.4 6.7 32.7 9.6 6.1 32.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Trm112p PF03966.16 CCC67114.1 - 2.7e-19 69.5 0.1 3.4e-19 69.2 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein zf-ribbon_3 PF13248.6 CCC67114.1 - 0.057 12.8 0.1 0.14 11.6 0.1 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DUF35_N PF12172.8 CCC67114.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Pkinase PF00069.25 CCC67115.1 - 1.5e-78 263.8 0.0 2.7e-78 263.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67115.1 - 7.5e-32 110.6 0.0 2.8e-30 105.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC67115.1 - 4.8e-10 39.2 0.0 1.4e-05 24.6 0.0 2.5 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CCC67115.1 - 0.0055 15.5 0.0 0.016 14.0 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CCC67115.1 - 0.078 12.3 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCC67115.1 - 0.085 12.8 0.0 11 5.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family CDC50 PF03381.15 CCC67116.1 - 3.1e-91 305.8 0.5 3.7e-91 305.5 0.5 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Mso1_Sec1_bdg PF14475.6 CCC67117.1 - 2e-17 62.5 0.0 3.9e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 HAT_KAT11 PF08214.11 CCC67118.1 - 1e-98 330.9 0.0 1.2e-98 330.6 0.0 1.0 1 0 0 1 1 1 1 Histone acetylation protein Ribosomal_S6 PF01250.17 CCC67119.1 - 8.6e-24 83.6 0.1 1.5e-23 82.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S6 PAP2_3 PF14378.6 CCC67120.1 - 1.8e-25 89.8 11.5 1.8e-25 89.8 11.5 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CCC67120.1 - 1.7e-10 40.8 6.0 1.7e-10 40.8 6.0 2.4 2 0 0 2 2 2 1 PAP2 superfamily TFIIS_M PF07500.14 CCC67121.1 - 4e-20 72.4 1.6 4e-20 72.4 1.6 2.0 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 CCC67121.1 - 2e-10 40.4 5.2 4.2e-10 39.4 5.2 1.6 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.13 CCC67121.1 - 0.00022 21.2 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 SPOC domain PHD_Oberon PF07227.11 CCC67121.1 - 0.07 13.0 2.2 0.16 11.9 2.2 1.5 1 0 0 1 1 1 0 PHD - plant homeodomain finger protein RSB_motif PF16294.5 CCC67121.1 - 0.39 11.0 9.3 0.12 12.6 1.0 2.8 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif C1_1 PF00130.22 CCC67121.1 - 0.76 9.7 2.6 2.8 7.9 0.5 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 CCC67121.1 - 5.3 7.4 7.3 9.6 6.6 1.9 2.7 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 CCC67121.1 - 6.3 6.8 8.4 33 4.5 7.7 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Ribosomal_L14e PF01929.17 CCC67122.1 - 1.2e-32 112.2 2.0 1.9e-32 111.6 2.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CCC67122.1 - 0.0012 18.7 0.4 0.0012 18.7 0.4 2.1 2 0 0 2 2 2 1 KOW motif DUF1043 PF06295.12 CCC67123.1 - 0.012 15.7 0.3 0.013 15.5 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Use1 PF09753.9 CCC67123.1 - 0.022 14.5 0.3 0.028 14.1 0.2 1.3 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF2451 PF10474.9 CCC67123.1 - 0.028 14.2 0.1 0.031 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2451) HemX PF04375.14 CCC67123.1 - 0.029 13.7 1.8 0.036 13.4 1.8 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Plasmodium_Vir PF05795.11 CCC67123.1 - 0.056 12.9 0.4 0.059 12.8 0.4 1.0 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Synaptobrevin PF00957.21 CCC67123.1 - 0.067 13.0 3.4 0.19 11.5 3.4 1.8 1 1 0 1 1 1 0 Synaptobrevin CCCAP PF15964.5 CCC67123.1 - 0.082 11.2 0.0 0.089 11.1 0.0 1.0 1 0 0 1 1 1 0 Centrosomal colon cancer autoantigen protein family F-actin_cap_A PF01267.17 CCC67124.1 - 8.7e-78 261.4 1.0 9.9e-78 261.2 1.0 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Sacchrp_dh_C PF16653.5 CCC67125.1 - 1e-93 314.3 0.0 1.8e-93 313.5 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 CCC67125.1 - 1.6e-24 86.6 0.2 2.4e-24 86.0 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 CCC67125.1 - 2.7e-07 30.6 0.2 5e-07 29.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 CCC67125.1 - 3.8e-07 30.3 0.1 8.2e-07 29.2 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 CCC67125.1 - 0.014 16.2 0.2 0.036 14.9 0.2 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 CCC67125.1 - 0.042 14.5 0.2 0.098 13.3 0.2 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain ZNRF_3_ecto PF18212.1 CCC67125.1 - 0.064 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 ZNRF-3 Ectodomain NTF2 PF02136.20 CCC67126.1 - 9.4e-17 61.7 0.3 1.9e-16 60.7 0.3 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain YqzE PF14038.6 CCC67126.1 - 0.011 15.7 0.6 0.011 15.7 0.6 3.1 3 0 0 3 3 3 0 YqzE-like protein CAF1 PF04857.20 CCC67127.1 - 7.3e-16 58.2 4.9 1e-09 38.0 0.1 2.9 2 1 1 3 3 3 2 CAF1 family ribonuclease Hydin_ADK PF17213.3 CCC67127.1 - 1.5 9.1 3.7 2.4 8.4 3.7 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Mvb12 PF09452.10 CCC67127.1 - 6 7.4 11.3 3.7 8.0 0.8 3.0 2 1 1 3 3 3 0 ESCRT-I subunit Mvb12 Roughex PF06020.11 CCC67127.1 - 8.1 5.4 6.3 12 4.9 6.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein NGP1NT PF08153.12 CCC67128.1 - 3.4e-52 176.0 0.4 5.8e-52 175.3 0.4 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 CCC67128.1 - 1.1e-17 64.2 0.0 1.9e-13 50.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CCC67128.1 - 1.8e-05 24.3 0.0 8.7e-05 22.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 CCC67128.1 - 0.00093 18.7 0.1 0.16 11.4 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.23 CCC67128.1 - 0.0011 19.1 0.1 0.82 9.7 0.0 3.4 2 1 1 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 CCC67128.1 - 0.0025 17.7 0.0 0.0072 16.2 0.0 1.7 1 1 0 1 1 1 1 RsgA GTPase GTP_EFTU PF00009.27 CCC67128.1 - 0.0042 16.6 0.6 0.47 10.0 0.2 3.4 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain RRM_1 PF00076.22 CCC67129.1 - 0.00014 21.6 0.0 0.021 14.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cas_Cas4 PF01930.17 CCC67129.1 - 2.7 8.1 10.5 7 6.7 1.8 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF83 RNA_pol_Rpc4 PF05132.14 CCC67129.1 - 7.7 6.9 14.6 1.9 8.9 4.9 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 VPS38 PF17649.1 CCC67129.1 - 8.7 5.1 15.4 0.14 11.0 5.8 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 38 MFS_1 PF07690.16 CCC67130.1 - 1.7e-34 119.3 47.6 2.7e-33 115.4 47.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Aminotran_1_2 PF00155.21 CCC67131.1 - 2.2e-84 283.7 0.0 2.6e-84 283.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_M18 PF02127.15 CCC67132.1 - 1.7e-144 481.8 0.0 2.4e-144 481.4 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) SIS PF01380.22 CCC67133.1 - 3.1e-68 227.7 0.1 1e-34 119.2 0.1 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 CCC67133.1 - 6.2e-15 55.6 0.0 1.3e-14 54.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CCC67133.1 - 1e-09 38.3 0.0 2.3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 CCC67133.1 - 2.4e-05 23.4 0.0 4.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pkinase PF00069.25 CCC67135.1 - 6.6e-71 238.8 0.1 1.6e-64 217.8 0.0 2.9 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67135.1 - 3.3e-35 121.6 0.0 1.7e-33 116.0 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 CCC67135.1 - 0.0034 16.8 0.0 0.0069 15.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CCC67135.1 - 0.0095 15.5 0.0 0.0095 15.5 0.0 2.6 3 0 0 3 3 3 1 Choline/ethanolamine kinase APH PF01636.23 CCC67135.1 - 0.026 14.5 0.0 0.056 13.4 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Utp11 PF03998.13 CCC67136.1 - 2e-69 234.3 29.7 2.3e-69 234.1 29.7 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 CCC67136.1 - 0.12 11.6 2.7 0.58 9.5 0.1 2.2 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 RVT_2 PF07727.14 CCC67138.1 - 5.8e-11 42.5 0.9 1e-10 41.7 0.9 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cys_Met_Meta_PP PF01053.20 CCC67139.1 - 2.7e-145 483.7 0.0 3.2e-145 483.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CCC67139.1 - 1.2e-09 38.0 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CCC67139.1 - 6.6e-09 35.2 0.2 9.9e-09 34.6 0.2 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CCC67139.1 - 7.8e-09 35.2 0.0 1.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CCC67139.1 - 2.6e-05 23.7 0.0 4.4e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.11 CCC67139.1 - 0.019 13.5 0.1 0.028 12.9 0.1 1.4 1 1 0 1 1 1 0 Methionine gamma-lyase RNase_PH PF01138.21 CCC67140.1 - 2.3e-16 60.5 0.3 5.1e-16 59.4 0.1 1.6 1 1 1 2 2 2 1 3' exoribonuclease family, domain 1 Flavodoxin_3 PF12641.7 CCC67140.1 - 0.054 13.2 0.7 1 9.0 0.0 2.7 3 0 0 3 3 3 0 Flavodoxin domain RRM_1 PF00076.22 CCC67141.1 - 6.1e-20 70.8 0.0 1.1e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 CCC67141.1 - 4.7e-09 36.6 0.4 4.7e-09 36.6 0.4 1.7 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 CCC67141.1 - 2.5e-07 30.2 1.0 4.4e-07 29.4 1.0 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal RRM_occluded PF16842.5 CCC67141.1 - 0.0045 16.8 0.0 0.0093 15.8 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif TFIIS_M PF07500.14 CCC67142.1 - 5.5e-26 91.2 2.5 5.5e-26 91.2 2.5 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 CCC67142.1 - 1.9e-17 62.8 6.4 3.2e-17 62.1 6.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 CCC67142.1 - 3.6e-11 42.9 2.1 1.2e-10 41.3 2.1 2.0 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF4050 PF13259.6 CCC67142.1 - 0.35 11.2 7.7 0.62 10.4 7.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) HypA PF01155.19 CCC67142.1 - 0.64 10.0 3.9 0.26 11.3 0.8 1.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RDM PF11002.8 CCC67143.1 - 0.049 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 RFPL defining motif (RDM) HATPase_c_3 PF13589.6 CCC67143.1 - 0.056 13.3 0.4 0.095 12.5 0.3 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TYW3 PF02676.14 CCC67144.1 - 2.5e-67 226.4 0.0 3.9e-67 225.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase TYW3 MIF4G PF02854.19 CCC67145.1 - 2e-49 168.1 0.1 3.4e-49 167.4 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 CCC67145.1 - 1.9e-23 82.4 1.2 1.9e-23 82.4 1.2 2.5 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 AAA PF00004.29 CCC67146.1 - 7.2e-43 146.2 0.0 1.4e-42 145.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC67146.1 - 1.1e-14 54.0 0.5 3.1e-14 52.5 0.0 2.0 3 0 0 3 3 1 1 AAA+ lid domain AAA_2 PF07724.14 CCC67146.1 - 1.2e-06 28.7 0.0 2.7e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCC67146.1 - 1.9e-06 27.9 0.0 1.2e-05 25.3 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 CCC67146.1 - 2e-06 27.6 0.8 4.6e-06 26.5 0.8 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CCC67146.1 - 2.7e-05 24.6 0.1 0.00033 21.1 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCC67146.1 - 3.5e-05 24.1 0.2 0.006 16.9 0.2 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 CCC67146.1 - 0.0001 22.1 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CCC67146.1 - 0.001 19.6 0.3 0.022 15.3 0.0 2.8 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 CCC67146.1 - 0.0015 18.3 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 CCC67146.1 - 0.0023 18.1 0.0 0.005 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CCC67146.1 - 0.0043 17.3 0.0 0.0088 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CCC67146.1 - 0.0067 16.3 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2072 PF09845.9 CCC67146.1 - 0.0097 16.2 0.1 0.02 15.1 0.1 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein Mg_chelatase PF01078.21 CCC67146.1 - 0.011 15.1 0.2 0.029 13.8 0.0 1.6 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 CCC67146.1 - 0.012 14.9 0.0 0.029 13.6 0.0 1.6 1 1 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 CCC67146.1 - 0.019 15.0 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 CCC67146.1 - 0.02 14.9 0.0 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 CCC67146.1 - 0.021 14.3 0.0 0.077 12.4 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.26 CCC67146.1 - 0.03 14.0 0.0 0.17 11.6 0.0 2.2 3 0 0 3 3 3 0 Sigma-54 interaction domain RNA_helicase PF00910.22 CCC67146.1 - 0.039 14.3 0.0 0.092 13.1 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 CCC67146.1 - 0.047 13.4 0.0 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CCC67146.1 - 0.048 14.0 0.1 0.65 10.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCC67146.1 - 0.056 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 CCC67146.1 - 0.084 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 CCC67146.1 - 0.092 11.9 0.2 0.19 10.9 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 CCC67146.1 - 0.1 11.8 0.0 0.25 10.6 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 CCC67146.1 - 0.1 12.3 0.0 0.33 10.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain Parvo_NS1 PF01057.17 CCC67146.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF3372 PF11852.8 CCC67146.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3372) ATG16 PF08614.11 CCC67146.1 - 0.21 11.8 2.8 0.36 11.0 2.8 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Tropomyosin PF00261.20 CCC67146.1 - 0.22 10.8 3.2 0.24 10.8 1.0 1.9 2 0 0 2 2 2 0 Tropomyosin RRM_1 PF00076.22 CCC67147.1 - 3.1e-45 151.9 0.0 1.1e-21 76.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC67147.1 - 0.00075 19.6 0.0 1.5 9.0 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CCC67147.1 - 0.0047 16.9 0.0 0.76 9.8 0.0 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 CCC67147.1 - 0.0078 16.2 0.1 0.65 10.0 0.0 2.3 2 0 0 2 2 2 1 DbpA RNA binding domain Mitofilin PF09731.9 CCC67147.1 - 0.024 13.5 31.9 0.034 13.0 31.9 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RRM_occluded PF16842.5 CCC67147.1 - 0.044 13.7 0.0 2.6 7.9 0.0 2.4 2 1 0 2 2 2 0 Occluded RNA-recognition motif RRM_5 PF13893.6 CCC67147.1 - 0.065 12.8 0.0 2.9 7.5 0.0 2.3 1 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SOG2 PF10428.9 CCC67147.1 - 0.32 10.1 27.4 0.38 9.9 27.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Arrestin_N PF00339.29 CCC67148.1 - 3.9e-20 72.4 0.2 1.3e-19 70.7 0.2 2.0 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 CCC67148.1 - 6.8e-08 33.1 9.0 2.1e-07 31.5 0.1 3.1 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Aconitase PF00330.20 CCC67150.1 - 2.4e-151 504.9 0.0 3.1e-151 504.5 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCC67150.1 - 1.1e-47 161.6 0.0 2.3e-47 160.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain PI3_PI4_kinase PF00454.27 CCC67151.1 - 1.4e-44 152.8 0.0 3.1e-42 145.1 0.0 2.6 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 CCC67151.1 - 4.5e-27 94.7 0.0 1.3e-26 93.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) RasGEF_N PF00618.20 CCC67151.1 - 0.86 9.9 3.4 3.9 7.8 0.1 3.4 3 0 0 3 3 3 0 RasGEF N-terminal motif UQ_con PF00179.26 CCC67152.1 - 4.3e-37 126.9 0.0 5.1e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 CCC67152.1 - 0.12 12.3 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 UEV domain Polysacc_deac_1 PF01522.21 CCC67153.1 - 1.8e-27 95.7 0.1 3.2e-27 94.9 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.15 CCC67153.1 - 9.6e-05 21.7 0.0 0.00013 21.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 GRIP PF01465.20 CCC67154.1 - 8e-13 48.1 0.5 2.2e-12 46.7 0.5 1.8 1 0 0 1 1 1 1 GRIP domain SOAR PF16533.5 CCC67154.1 - 0.00097 19.1 4.0 0.00097 19.1 4.0 7.8 5 3 3 9 9 9 1 STIM1 Orai1-activating region Spc7 PF08317.11 CCC67154.1 - 0.0031 16.4 23.4 0.0031 16.4 23.4 7.8 2 2 6 8 8 8 3 Spc7 kinetochore protein EF-hand_11 PF08976.11 CCC67154.1 - 0.059 14.2 1.8 2.1 9.2 0.7 3.5 2 0 0 2 2 2 0 EF-hand domain RasGEF PF00617.19 CCC67155.1 - 3.1e-57 193.6 3.8 1e-56 192.0 0.3 3.1 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 CCC67155.1 - 2.7e-19 69.4 0.2 2.7e-19 69.4 0.2 3.3 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.28 CCC67155.1 - 5.7e-11 41.9 0.1 1.2e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCC67155.1 - 1e-10 41.3 0.0 2.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCC67155.1 - 2.6e-06 27.0 0.0 1.7e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain DUF3232 PF11554.8 CCC67155.1 - 0.051 14.0 1.2 0.16 12.3 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3232) tRNA-synt_2 PF00152.20 CCC67156.1 - 1.1e-76 257.9 0.1 1.8e-76 257.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCC67156.1 - 2.3e-07 30.7 0.6 4.4e-07 29.8 0.6 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCC67156.1 - 0.016 14.7 0.7 2.1 7.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DDE_Tnp_IS240 PF13610.6 CCC67156.1 - 0.59 10.3 2.9 1.5 9.0 1.2 2.4 3 0 0 3 3 3 0 DDE domain CHCH PF06747.13 CCC67157.1 - 0.00064 19.8 3.3 0.0013 18.8 3.3 1.5 1 1 0 1 1 1 1 CHCH domain Pet191_N PF10203.9 CCC67157.1 - 0.028 14.7 4.5 0.14 12.5 4.6 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 CCC67157.1 - 0.031 14.5 0.3 0.04 14.1 0.3 1.1 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb CX9C PF16860.5 CCC67157.1 - 0.088 12.8 4.7 0.13 12.3 4.7 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, COX17 PF05051.13 CCC67157.1 - 0.15 12.4 3.6 2.3 8.6 0.7 2.1 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Pkinase PF00069.25 CCC67158.1 - 2.1e-42 145.4 2.8 6.1e-42 143.8 0.0 2.8 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67158.1 - 1e-16 61.0 0.0 2.5e-16 59.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCC67158.1 - 0.013 14.9 0.0 0.032 13.6 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCC67158.1 - 0.09 12.1 0.0 0.21 10.8 0.0 1.6 1 0 0 1 1 1 0 Kinase-like NOA36 PF06524.12 CCC67158.1 - 3.5 6.9 5.9 7 5.9 5.9 1.4 1 0 0 1 1 1 0 NOA36 protein GIT_SHD PF08518.11 CCC67159.1 - 3.1e-25 87.5 5.1 6.1e-12 44.9 0.4 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 CCC67159.1 - 1.3e-05 25.3 1.3 1.3e-05 25.3 1.3 2.9 2 0 0 2 2 2 1 G protein-coupled receptor kinase-interacting protein 1 C term bZIP_1 PF00170.21 CCC67159.1 - 0.047 13.8 12.5 0.7 10.0 4.9 3.6 2 0 0 2 2 2 0 bZIP transcription factor GIT_CC PF16559.5 CCC67159.1 - 0.27 11.1 13.8 0.58 10.1 4.1 2.9 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Snapin_Pallidin PF14712.6 CCC67159.1 - 0.97 9.9 9.0 5.6 7.5 9.0 2.5 1 0 0 1 1 1 0 Snapin/Pallidin TSC22 PF01166.18 CCC67159.1 - 9.1 6.7 14.9 7.7 6.9 0.8 5.1 3 1 1 4 4 4 0 TSC-22/dip/bun family DUF2247 PF10004.9 CCC67160.1 - 0.0025 17.6 1.6 0.0063 16.3 1.6 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2247) TPR_12 PF13424.6 CCC67160.1 - 0.0073 16.6 1.1 0.033 14.5 0.3 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CCC67160.1 - 0.014 14.8 0.3 0.028 13.9 0.3 1.6 1 0 0 1 1 1 0 SHNi-TPR Nop14 PF04147.12 CCC67160.1 - 0.047 11.9 16.4 0.07 11.3 16.4 1.3 1 0 0 1 1 1 0 Nop14-like family UPF0121 PF03661.13 CCC67161.1 - 1.1e-26 93.8 11.6 1.4e-26 93.4 11.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DUF2214 PF09980.9 CCC67161.1 - 0.041 13.7 4.6 0.88 9.4 0.6 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2214) rve PF00665.26 CCC67162.1 - 3.4e-07 30.5 0.0 8.4e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Integrase core domain T6PP_N PF18572.1 CCC67162.1 - 0.027 14.3 1.4 0.072 12.9 1.4 1.8 1 1 0 1 1 1 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF2183 PF09949.9 CCC67162.1 - 0.057 13.8 0.0 0.21 12.0 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2183) DUF2746 PF10874.8 CCC67162.1 - 0.17 12.3 0.4 0.45 11.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) DUF2264 PF10022.9 CCC67163.1 - 0.018 14.1 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Corona_S2 PF01601.16 CCC67163.1 - 0.14 10.6 2.5 0.24 9.9 2.5 1.3 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Fzo_mitofusin PF04799.13 CCC67163.1 - 4.4 6.8 8.8 0.091 12.3 0.4 2.4 3 0 0 3 3 3 0 fzo-like conserved region Ribosomal_S3Ae PF01015.18 CCC67164.1 - 8.5e-87 289.9 5.5 1e-86 289.7 5.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DLP_helical PF18709.1 CCC67164.1 - 0.0059 15.9 0.2 0.0089 15.3 0.2 1.2 1 0 0 1 1 1 1 Dynamin-like helical domain ISAV_HA PF06215.11 CCC67164.1 - 0.023 13.9 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin HIGH_NTase1_ass PF16581.5 CCC67164.1 - 0.03 14.3 0.2 0.041 13.9 0.2 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Abhydro_lipase PF04083.16 CCC67164.1 - 0.036 13.6 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ras PF00071.22 CCC67165.1 - 1.1e-30 106.4 0.1 1.3e-30 106.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC67165.1 - 4e-21 75.5 0.0 5.9e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CCC67165.1 - 9e-06 25.2 0.1 1.1e-05 24.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CCC67165.1 - 0.00026 20.5 0.1 0.00033 20.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DLIC PF05783.11 CCC67165.1 - 0.00083 18.3 0.4 0.038 12.8 0.1 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.23 CCC67165.1 - 0.003 17.6 0.0 0.0044 17.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 CCC67165.1 - 0.021 14.3 0.2 0.075 12.5 0.0 1.9 2 1 1 3 3 3 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 CCC67165.1 - 0.04 13.7 0.1 0.17 11.6 0.0 1.8 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_lid_10 PF17872.1 CCC67166.1 - 5.4e-35 119.5 3.1 5.6e-35 119.4 0.1 2.7 3 1 1 4 4 4 1 AAA lid domain AAA PF00004.29 CCC67166.1 - 2.1e-20 73.5 0.1 7e-20 71.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.18 CCC67166.1 - 2.6e-11 43.5 0.3 9.3e-11 41.6 0.3 2.1 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.6 CCC67166.1 - 8.8e-07 29.3 0.0 3.1e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCC67166.1 - 4.1e-06 27.3 0.0 7.7e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 CCC67166.1 - 0.0045 17.3 0.0 0.018 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCC67166.1 - 0.012 15.6 0.0 0.031 14.2 0.0 1.7 1 1 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 CCC67166.1 - 0.039 14.3 0.0 0.2 12.0 0.0 2.3 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.6 CCC67166.1 - 0.72 9.6 0.0 0.72 9.6 0.0 3.0 3 1 0 3 3 3 0 AAA domain Claudin_2 PF13903.6 CCC67167.1 - 0.00055 19.7 0.5 0.00055 19.7 0.5 1.8 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Fig1 PF12351.8 CCC67167.1 - 0.79 9.6 7.6 8 6.3 0.1 3.1 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 COPIIcoated_ERV PF07970.12 CCC67168.1 - 3.9e-30 105.4 0.0 5.8e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCC67168.1 - 1.2e-22 80.1 0.0 2.3e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) IBR PF01485.21 CCC67169.1 - 7.5e-15 54.9 45.5 6.7e-09 35.8 4.1 4.1 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 CCC67169.1 - 0.0024 18.2 8.4 0.0024 18.2 8.4 4.2 3 2 1 4 4 4 1 Ring finger domain RWD PF05773.22 CCC67169.1 - 0.057 13.7 0.4 0.057 13.7 0.4 2.4 3 0 0 3 3 3 0 RWD domain zf-RING_4 PF14570.6 CCC67169.1 - 7.7 6.4 43.4 0.073 12.9 7.5 4.6 4 1 1 5 5 5 0 RING/Ubox like zinc-binding domain SSrecog PF03531.14 CCC67170.1 - 2.7e-30 104.1 2.0 2e-28 98.1 0.0 3.5 3 0 0 3 3 3 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 CCC67170.1 - 6.3e-29 100.3 0.5 4.7e-26 91.0 0.1 2.8 3 0 0 3 3 3 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 CCC67170.1 - 1.6e-28 98.9 0.1 1.8e-25 89.1 0.0 3.3 3 0 0 3 3 3 1 Histone chaperone Rttp106-like Dak1 PF02733.17 CCC67171.1 - 8.4e-111 369.8 0.8 1.2e-110 369.3 0.8 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 CCC67171.1 - 4.8e-46 156.8 1.8 6.1e-46 156.5 1.0 1.6 2 0 0 2 2 2 1 DAK2 domain UPF0184 PF03670.13 CCC67171.1 - 0.13 12.6 0.1 0.88 10.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Dor1 PF04124.12 CCC67172.1 - 1.1e-42 146.0 10.5 1.1e-42 146.0 10.5 1.8 2 1 0 2 2 2 1 Dor1-like family Lzipper-MIP1 PF14389.6 CCC67172.1 - 0.0054 17.0 0.4 0.033 14.5 0.4 2.4 1 0 0 1 1 1 1 Leucine-zipper of ternary complex factor MIP1 TPR_7 PF13176.6 CCC67172.1 - 0.11 12.6 0.0 0.41 10.8 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat RNA_pol_Rpb5_N PF03871.14 CCC67172.1 - 0.15 12.7 1.0 0.27 11.8 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain ABC_tran_CTD PF16326.5 CCC67172.1 - 0.41 10.9 2.9 0.33 11.2 0.5 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain Eaf7 PF07904.13 CCC67172.1 - 0.95 9.9 4.8 1.6 9.2 4.1 1.7 1 1 0 1 1 1 0 Chromatin modification-related protein EAF7 C2 PF00168.30 CCC67173.1 - 2.3e-65 217.3 5.5 2.6e-22 79.1 0.0 5.8 6 0 0 6 6 6 5 C2 domain SMP_LBD PF17047.5 CCC67173.1 - 3.1e-05 23.5 0.1 0.0017 17.9 0.1 2.4 1 1 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain OmpH PF03938.14 CCC67173.1 - 0.03 14.6 5.3 0.09 13.1 5.3 1.8 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Ribosomal_L6e PF01159.19 CCC67174.1 - 4.2e-38 130.3 3.0 6e-38 129.8 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e FKBP_C PF00254.28 CCC67175.1 - 8e-29 99.8 0.2 2.8e-28 98.1 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CCC67175.1 - 1.8e-19 70.3 4.9 1.8e-19 70.3 4.9 2.8 2 2 0 2 2 1 1 Nucleoplasmin-like domain BUD22 PF09073.10 CCC67175.1 - 0.00037 20.0 38.2 0.00051 19.5 38.2 1.1 1 0 0 1 1 1 1 BUD22 Rtf2 PF04641.12 CCC67175.1 - 0.12 11.7 27.6 0.016 14.6 3.6 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger Mpp10 PF04006.12 CCC67175.1 - 0.5 8.7 49.1 0.38 9.1 18.0 2.1 2 0 0 2 2 2 0 Mpp10 protein Nop53 PF07767.11 CCC67175.1 - 0.51 9.7 45.7 0.033 13.6 15.9 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Pex14_N PF04695.13 CCC67175.1 - 1.1 9.9 7.6 13 6.4 3.8 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1764 PF08576.10 CCC67175.1 - 1.3 9.9 34.5 5.7 7.9 10.2 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) GAGA_bind PF06217.12 CCC67175.1 - 2.1 8.5 18.9 5.4 7.2 2.4 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family CCSAP PF15748.5 CCC67175.1 - 2.8 8.1 24.2 4.4 7.4 5.5 2.1 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Vfa1 PF08432.10 CCC67175.1 - 5.3 7.3 37.5 2.7 8.3 11.0 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 HMG-CoA_red PF00368.18 CCC67176.1 - 3.7e-141 470.4 0.1 4.8e-141 470.0 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.6 CCC67176.1 - 5.3e-49 166.1 3.0 1.3e-48 164.7 3.0 1.8 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.8 CCC67176.1 - 3.7e-06 26.8 6.9 3.7e-06 26.8 6.9 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation Zn_clus PF00172.18 CCC67177.1 - 0.007 16.5 9.7 0.017 15.2 9.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sybindin PF04099.12 CCC67178.1 - 4.3e-20 72.1 0.6 5.6e-20 71.7 0.6 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 CCC67178.1 - 0.008 16.3 1.2 0.011 15.8 1.2 1.4 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region RecG_wedge PF17191.4 CCC67178.1 - 0.014 15.0 0.1 0.018 14.7 0.1 1.2 1 0 0 1 1 1 0 RecG wedge domain ENTH PF01417.20 CCC67179.1 - 1.8e-43 147.6 0.1 3.2e-43 146.8 0.1 1.4 1 0 0 1 1 1 1 ENTH domain VHS PF00790.19 CCC67179.1 - 8e-05 22.5 0.1 0.00014 21.7 0.1 1.3 1 0 0 1 1 1 1 VHS domain ANTH PF07651.16 CCC67179.1 - 0.0029 16.6 0.0 0.0044 16.0 0.0 1.3 1 0 0 1 1 1 1 ANTH domain Pro_isomerase PF00160.21 CCC67180.1 - 1.6e-49 168.2 0.2 1.8e-49 168.0 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PDE6_gamma PF04868.12 CCC67180.1 - 0.099 12.9 0.9 3 8.1 0.1 2.6 2 1 0 2 2 2 0 Retinal cGMP phosphodiesterase, gamma subunit Cupin_5 PF06172.11 CCC67181.1 - 8.1e-46 155.7 0.0 9.7e-46 155.4 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Dus PF01207.17 CCC67182.1 - 1.4e-79 267.4 0.0 1.8e-79 267.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-H2C2_2 PF13465.6 CCC67183.1 - 2.3e-06 27.8 10.1 4e-05 23.8 4.9 2.6 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.26 CCC67183.1 - 3.8e-06 27.0 14.7 0.00019 21.7 3.0 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC67183.1 - 0.008 16.9 14.0 0.044 14.6 2.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger ATP-synt_J PF04911.12 CCC67184.1 - 1e-29 101.8 1.5 1.2e-29 101.6 1.5 1.1 1 0 0 1 1 1 1 ATP synthase j chain Cys_Met_Meta_PP PF01053.20 CCC67185.1 - 2e-24 85.8 0.0 1e-14 53.9 0.0 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 CCC67185.1 - 0.013 14.7 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Ctf8 PF09696.10 CCC67186.1 - 5.2e-16 59.3 4.3 2.5e-10 40.9 2.0 3.0 1 1 1 2 2 2 2 Ctf8 zinc_ribbon_10 PF10058.9 CCC67187.1 - 4.9e-15 55.0 0.1 8.2e-15 54.3 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein 4HB_MCP_1 PF12729.7 CCC67187.1 - 0.0012 18.4 7.1 0.36 10.4 5.6 2.3 2 0 0 2 2 2 2 Four helix bundle sensory module for signal transduction End3 PF12761.7 CCC67187.1 - 0.009 16.2 0.8 0.009 16.2 0.8 2.3 2 0 0 2 2 2 1 Actin cytoskeleton-regulatory complex protein END3 TBCC_N PF16752.5 CCC67187.1 - 0.031 14.7 10.4 1.2 9.6 0.4 2.4 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain CoA_binding_3 PF13727.6 CCC67187.1 - 0.04 13.9 0.3 0.06 13.4 0.3 1.3 1 0 0 1 1 1 0 CoA-binding domain SKA1 PF07160.12 CCC67187.1 - 0.051 13.4 7.1 0.37 10.6 0.1 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 LPG_synthase_TM PF03706.13 CCC67187.1 - 0.051 13.1 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region DUF2721 PF11026.8 CCC67187.1 - 0.064 13.1 0.2 0.064 13.1 0.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2721) DLP_helical PF18709.1 CCC67187.1 - 0.084 12.1 3.7 0.13 11.4 0.1 2.1 1 1 1 2 2 2 0 Dynamin-like helical domain AI-2E_transport PF01594.16 CCC67187.1 - 0.087 12.0 3.5 0.044 12.9 1.4 1.5 1 1 0 1 1 1 0 AI-2E family transporter U3_assoc_6 PF08640.11 CCC67187.1 - 0.1 12.7 0.1 0.1 12.7 0.1 2.4 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 Rubredoxin PF00301.20 CCC67187.1 - 0.13 12.4 0.1 3.9 7.6 0.1 2.3 2 0 0 2 2 2 0 Rubredoxin CENP-F_N PF10481.9 CCC67187.1 - 0.28 10.8 11.9 2.1 7.9 0.3 3.1 2 1 1 3 3 3 0 Cenp-F N-terminal domain DASH_Duo1 PF08651.10 CCC67187.1 - 0.43 10.4 9.6 0.22 11.3 0.4 2.6 3 0 0 3 3 2 0 DASH complex subunit Duo1 A2L_zn_ribbon PF08792.10 CCC67187.1 - 0.56 10.0 4.1 1.7 8.5 0.2 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF745 PF05335.13 CCC67187.1 - 0.97 9.1 6.0 9.1 6.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) CCDC-167 PF15188.6 CCC67187.1 - 1.5 9.2 8.9 15 6.0 4.9 3.0 2 1 1 3 3 3 0 Coiled-coil domain-containing protein 167 DUF641 PF04859.12 CCC67187.1 - 2.4 8.5 9.7 5.7 7.3 6.6 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) zf-Mss51 PF13824.6 CCC67187.1 - 7.1 6.8 5.5 1.5 8.9 0.7 2.3 3 0 0 3 3 2 0 Zinc-finger of mitochondrial splicing suppressor 51 NAC PF01849.18 CCC67188.1 - 1.3e-18 66.7 0.2 2.9e-18 65.6 0.2 1.6 1 0 0 1 1 1 1 NAC domain UBA_4 PF14555.6 CCC67188.1 - 0.093 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain ABC_tran PF00005.27 CCC67189.1 - 2.6e-46 157.6 0.0 3.6e-23 82.6 0.0 4.3 2 2 0 2 2 2 2 ABC transporter 4HB PF17947.1 CCC67189.1 - 8.8e-26 89.8 0.3 2.8e-25 88.2 0.3 2.0 1 0 0 1 1 1 1 Four helical bundle domain SMC_N PF02463.19 CCC67189.1 - 2.3e-16 59.9 0.3 2e-07 30.7 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CCC67189.1 - 5.8e-16 59.2 7.1 0.008 16.0 0.0 5.2 5 1 0 6 6 5 4 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CCC67189.1 - 3.2e-10 40.8 4.6 0.00023 21.7 0.1 3.8 4 0 0 4 4 3 2 AAA domain AAA_22 PF13401.6 CCC67189.1 - 8.1e-09 35.9 0.3 0.0027 18.0 0.0 4.9 5 1 0 5 5 5 2 AAA domain AAA_28 PF13521.6 CCC67189.1 - 1.3e-08 35.3 0.0 0.00053 20.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CCC67189.1 - 1.4e-08 34.4 0.0 0.0055 16.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCC67189.1 - 2.4e-08 34.0 0.2 0.0012 18.8 0.0 3.2 2 1 1 3 3 3 2 RsgA GTPase Dynamin_N PF00350.23 CCC67189.1 - 4.5e-08 33.3 0.0 9.7e-06 25.7 0.0 2.9 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 CCC67189.1 - 5.8e-08 32.8 0.0 0.0023 18.0 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.22 CCC67189.1 - 3.3e-06 27.4 0.0 0.16 12.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA PF00004.29 CCC67189.1 - 3.6e-06 27.4 0.1 0.086 13.3 0.0 4.4 5 0 0 5 5 3 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CCC67189.1 - 4e-06 27.4 0.0 0.15 12.6 0.0 3.3 3 0 0 3 3 2 2 AAA domain MeaB PF03308.16 CCC67189.1 - 8.6e-06 24.9 0.0 0.088 11.8 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 CCC67189.1 - 6.3e-05 23.2 0.0 0.35 11.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain ParcG PF10274.9 CCC67189.1 - 8.1e-05 22.8 1.5 0.62 10.2 0.0 3.3 2 1 1 3 3 3 2 Parkin co-regulated protein AAA_16 PF13191.6 CCC67189.1 - 9.8e-05 22.8 0.0 0.32 11.4 0.0 3.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_14 PF13173.6 CCC67189.1 - 0.0001 22.3 0.0 0.2 11.7 0.0 3.4 4 0 0 4 4 2 1 AAA domain AAA_27 PF13514.6 CCC67189.1 - 0.00016 21.3 0.0 0.14 11.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain UME PF08064.13 CCC67189.1 - 0.00045 20.1 0.8 0.01 15.7 1.3 2.7 3 0 0 3 3 2 1 UME (NUC010) domain NACHT PF05729.12 CCC67189.1 - 0.0005 20.0 0.0 0.2 11.5 0.0 2.8 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 CCC67189.1 - 0.0006 19.4 0.1 3 7.4 0.0 4.1 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain Adaptin_N PF01602.20 CCC67189.1 - 0.00069 18.3 7.2 0.021 13.4 7.1 2.2 1 1 0 1 1 1 1 Adaptin N terminal region AAA_30 PF13604.6 CCC67189.1 - 0.00072 19.3 0.0 1.1 8.9 0.0 3.3 3 1 0 3 3 3 1 AAA domain HEAT_2 PF13646.6 CCC67189.1 - 0.00073 19.9 0.3 0.035 14.5 0.1 3.3 2 2 2 4 4 4 2 HEAT repeats Rad17 PF03215.15 CCC67189.1 - 0.00083 19.3 0.1 1.1 9.1 0.0 2.9 3 0 0 3 3 2 1 Rad17 P-loop domain PduV-EutP PF10662.9 CCC67189.1 - 0.00085 19.1 0.0 0.28 10.9 0.0 3.1 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.17 CCC67189.1 - 0.00086 19.5 6.3 0.36 10.9 0.0 4.5 6 0 0 6 6 3 1 Helicase HerA, central domain AAA_24 PF13479.6 CCC67189.1 - 0.0011 18.8 0.3 1.7 8.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain HEAT_EZ PF13513.6 CCC67189.1 - 0.0015 19.0 0.3 0.21 12.1 0.0 4.1 4 1 1 5 5 3 1 HEAT-like repeat CLP1_P PF16575.5 CCC67189.1 - 0.0016 18.3 0.0 0.19 11.5 0.0 3.0 3 0 0 3 3 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATPase_2 PF01637.18 CCC67189.1 - 0.0018 18.3 0.2 4.4 7.2 0.0 3.4 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DUF3385 PF11865.8 CCC67189.1 - 0.0025 17.8 1.4 1.9 8.3 0.1 3.4 1 1 1 2 2 2 1 Domain of unknown function (DUF3385) SbcCD_C PF13558.6 CCC67189.1 - 0.0036 17.5 0.0 0.75 10.1 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.6 CCC67189.1 - 0.006 15.3 1.9 1.1 7.9 0.0 3.4 4 0 0 4 4 4 1 AAA domain G-alpha PF00503.20 CCC67189.1 - 0.0073 15.5 0.8 3.5 6.7 0.1 2.7 3 0 0 3 3 3 0 G-protein alpha subunit IstB_IS21 PF01695.17 CCC67189.1 - 0.0078 16.0 0.0 1.5 8.5 0.0 2.9 2 0 0 2 2 2 1 IstB-like ATP binding protein CLASP_N PF12348.8 CCC67189.1 - 0.0082 15.7 1.3 1 8.9 0.3 2.7 1 1 1 2 2 2 1 CLASP N terminal Rcd1 PF04078.13 CCC67189.1 - 0.0098 15.2 2.4 0.013 14.8 0.6 2.1 2 0 0 2 2 1 1 Cell differentiation family, Rcd1-like Roc PF08477.13 CCC67189.1 - 0.011 15.9 0.0 7.7 6.8 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CCC67189.1 - 0.013 14.8 0.0 3.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Septin Cytidylate_kin PF02224.18 CCC67189.1 - 0.013 15.2 0.0 5.8 6.6 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_15 PF13175.6 CCC67189.1 - 0.021 14.6 12.4 0.29 10.8 0.0 4.2 6 0 0 6 6 4 0 AAA ATPase domain AAA_7 PF12775.7 CCC67189.1 - 0.022 14.3 0.0 8.3 5.9 0.0 2.7 2 1 0 2 2 2 0 P-loop containing dynein motor region HEAT PF02985.22 CCC67189.1 - 0.023 15.0 0.2 57 4.4 0.0 4.8 5 0 0 5 5 4 0 HEAT repeat NTPase_1 PF03266.15 CCC67189.1 - 0.028 14.3 0.1 12 5.8 0.0 2.8 2 0 0 2 2 2 0 NTPase NB-ARC PF00931.22 CCC67189.1 - 0.041 13.1 1.7 1.5 8.0 0.0 3.3 4 0 0 4 4 3 0 NB-ARC domain T2SSE PF00437.20 CCC67189.1 - 0.042 12.9 0.0 1.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 CCC67189.1 - 0.042 13.2 0.7 2.7 7.3 0.0 3.3 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI ATP_bind_1 PF03029.17 CCC67189.1 - 0.042 13.6 0.1 8 6.2 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Ploopntkinase3 PF18751.1 CCC67189.1 - 0.044 13.7 0.0 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Zeta_toxin PF06414.12 CCC67189.1 - 0.045 13.0 0.0 12 5.2 0.0 2.9 2 0 0 2 2 2 0 Zeta toxin MMS19_N PF14500.6 CCC67189.1 - 0.046 13.3 1.9 4.2 6.9 0.1 3.3 3 1 0 4 4 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Vac14_Fab1_bd PF12755.7 CCC67189.1 - 0.049 14.2 0.1 4.3 8.0 0.0 3.1 2 1 1 3 3 2 0 Vacuolar 14 Fab1-binding region MutS_V PF00488.21 CCC67189.1 - 0.051 13.6 0.0 6 6.8 0.0 2.8 2 0 0 2 2 2 0 MutS domain V GTP_EFTU PF00009.27 CCC67189.1 - 0.057 13.0 0.0 13 5.2 0.0 2.9 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain PRK PF00485.18 CCC67189.1 - 0.075 12.8 0.0 5.8 6.6 0.0 3.1 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.18 CCC67189.1 - 0.094 12.2 1.7 1.1 8.7 0.1 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF815 PF05673.13 CCC67189.1 - 0.096 11.8 0.0 4.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TsaE PF02367.17 CCC67189.1 - 0.1 12.6 0.0 8.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE dNK PF01712.19 CCC67189.1 - 0.1 12.5 0.0 13 5.6 0.0 2.7 2 0 0 2 2 2 0 Deoxynucleoside kinase RuvB_N PF05496.12 CCC67189.1 - 0.13 12.0 0.0 12 5.7 0.0 2.7 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain MukB PF04310.12 CCC67189.1 - 0.15 11.8 0.1 14 5.4 0.0 2.5 2 0 0 2 2 2 0 MukB N-terminal PIN_12 PF16289.5 CCC67189.1 - 1.9 9.0 4.7 0.67 10.4 0.1 2.7 3 0 0 3 3 1 0 PIN domain MDM31_MDM32 PF08118.11 CCC67190.1 - 2.4e-219 729.4 8.3 1.3e-218 727.0 8.3 1.8 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Ly49 PF08391.10 CCC67191.1 - 1.4 9.3 3.2 0.74 10.2 0.1 2.1 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region RIX1 PF08167.12 CCC67192.1 - 1.6e-51 174.8 1.7 1.6e-51 174.8 1.7 2.5 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis Orthopox_A47 PF06334.11 CCC67192.1 - 0.015 14.6 0.9 0.15 11.3 0.1 2.6 3 0 0 3 3 3 0 Orthopoxvirus A47 protein APT PF03440.14 CCC67192.1 - 0.045 13.7 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 Aerolysin/Pertussis toxin (APT) domain DUF281 PF03436.13 CCC67192.1 - 0.047 14.1 0.0 0.16 12.4 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF281) Chalcone_2 PF16035.5 CCC67193.1 - 1.6e-65 220.7 0.1 3.1e-65 219.8 0.0 1.5 2 0 0 2 2 2 1 Chalcone isomerase like Chalcone_3 PF16036.5 CCC67193.1 - 0.00089 19.4 0.2 0.0048 17.0 0.1 2.0 1 1 1 2 2 2 1 Chalcone isomerase-like Glyco_hydro_79n PF03662.14 CCC67193.1 - 0.11 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain VWA_2 PF13519.6 CCC67194.1 - 7.3e-20 71.6 0.7 2.2e-19 70.1 0.0 2.1 3 0 0 3 3 3 1 von Willebrand factor type A domain Ssl1 PF04056.14 CCC67194.1 - 9.8e-06 25.5 0.3 1.3e-05 25.1 0.3 1.2 1 0 0 1 1 1 1 Ssl1-like Homoserine_dh PF00742.19 CCC67195.1 - 1e-52 178.6 0.1 1.3e-52 178.2 0.1 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 CCC67195.1 - 2e-23 83.3 0.0 3.8e-23 82.4 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DHHA2 PF02833.14 CCC67196.1 - 1.8e-34 119.0 0.6 2.7e-34 118.4 0.6 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.20 CCC67196.1 - 1.4e-08 34.9 0.1 2.8e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 DHH family Nucleolin_bd PF16725.5 CCC67196.1 - 0.85 9.3 3.0 0.86 9.3 0.0 2.5 4 0 0 4 4 4 0 Nucleolin binding domain Mgm101p PF06420.12 CCC67197.1 - 1.5e-84 281.7 0.0 3.2e-84 280.6 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial genome maintenance MGM101 Metallophos PF00149.28 CCC67198.1 - 3.4e-13 50.6 4.3 5.7e-13 49.8 4.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase 5_nucleotid_C PF02872.18 CCC67198.1 - 0.044 14.0 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 5'-nucleotidase, C-terminal domain Ribosomal_S4e PF00900.20 CCC67199.1 - 6.7e-39 131.7 1.0 5.9e-38 128.6 0.7 2.2 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 CCC67199.1 - 1.4e-25 88.7 0.0 2.8e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CCC67199.1 - 2.4e-19 69.2 6.9 2.4e-19 69.2 6.9 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 CCC67199.1 - 4.2e-08 32.8 0.6 8.5e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 CCC67199.1 - 4.1e-06 26.5 1.8 4.1e-06 26.5 1.8 3.0 4 0 0 4 4 4 1 KOW motif DUF5072 PF16807.5 CCC67199.1 - 0.044 13.9 0.1 0.54 10.3 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5072) dCache_2 PF08269.11 CCC67199.1 - 0.05 12.8 0.1 0.12 11.5 0.0 1.7 1 1 0 1 1 1 0 Cache domain Dimer_Tnp_hAT PF05699.14 CCC67200.1 - 0.00034 20.4 0.1 0.00089 19.0 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Bravo_FIGEY PF13882.6 CCC67200.1 - 0.042 15.2 3.6 4.8 8.6 0.1 2.8 2 0 0 2 2 2 0 Bravo-like intracellular region Glyco_hydro_47 PF01532.20 CCC67201.1 - 3.3e-109 365.8 0.5 4.3e-109 365.4 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.25 CCC67202.1 - 4.1e-67 226.3 0.0 9.7e-67 225.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67202.1 - 5e-31 107.9 0.0 7.5e-31 107.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CCC67202.1 - 6.6e-11 42.7 1.7 2.9e-10 40.7 1.7 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain C2 PF00168.30 CCC67202.1 - 5.4e-10 39.5 0.0 2e-05 24.8 0.0 3.1 2 0 0 2 2 2 2 C2 domain Kinase-like PF14531.6 CCC67202.1 - 3.3e-09 36.5 0.0 1.2e-08 34.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 CCC67202.1 - 0.0025 16.8 0.7 0.0025 16.8 0.7 2.8 2 1 0 2 2 2 1 Haspin like kinase domain FTA2 PF13095.6 CCC67202.1 - 0.028 14.1 0.1 0.85 9.2 0.1 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 CCC67202.1 - 0.033 13.7 0.0 0.08 12.5 0.0 1.6 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Adeno_E3_15_3 PF03307.14 CCC67202.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Adenovirus 15.3kD protein in E3 region DUF737 PF05300.11 CCC67202.1 - 0.44 10.9 2.8 0.85 9.9 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) HSF_DNA-bind PF00447.17 CCC67203.1 - 2e-29 102.1 2.8 4.2e-29 101.0 2.8 1.6 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.24 CCC67203.1 - 1.5e-28 99.2 0.3 4.5e-28 97.6 0.3 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HALZ PF02183.18 CCC67203.1 - 0.0026 18.0 0.9 0.0053 16.9 0.9 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper SHE3 PF17078.5 CCC67203.1 - 0.0028 17.4 0.8 0.0028 17.4 0.8 1.7 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 YkyA PF10368.9 CCC67203.1 - 0.0041 16.8 0.4 0.0041 16.8 0.4 1.9 2 0 0 2 2 2 1 Putative cell-wall binding lipoprotein EzrA PF06160.12 CCC67203.1 - 0.011 13.9 1.5 0.013 13.7 0.3 1.6 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA Tup_N PF08581.10 CCC67203.1 - 0.026 14.8 0.2 0.7 10.2 0.1 2.4 2 0 0 2 2 2 0 Tup N-terminal Yuri_gagarin PF15934.5 CCC67203.1 - 0.027 14.3 2.0 0.034 14.0 0.2 1.9 2 0 0 2 2 2 0 Yuri gagarin Endotoxin_N PF03945.14 CCC67203.1 - 0.14 11.9 2.2 0.19 11.4 0.6 2.0 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain SET PF00856.28 CCC67204.1 - 3.8e-18 66.4 0.1 6.3e-18 65.7 0.1 1.4 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 CCC67204.1 - 4.9 7.3 12.8 0.62 10.2 6.5 2.5 2 0 0 2 2 2 0 MYND finger Zn_clus PF00172.18 CCC67207.1 - 0.00017 21.6 10.7 0.00029 20.9 10.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.32 CCC67209.1 - 3.2e-11 43.6 7.5 0.00024 21.8 0.0 5.4 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC67209.1 - 2.5e-05 24.5 0.0 0.058 13.7 0.0 4.1 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain MIT PF04212.18 CCC67210.1 - 0.034 14.2 0.8 2.2 8.4 0.1 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain CENP-K PF11802.8 CCC67210.1 - 0.038 13.6 9.8 0.016 14.8 6.2 1.9 1 1 1 2 2 2 0 Centromere-associated protein K STAT_alpha PF01017.20 CCC67210.1 - 0.039 13.8 4.7 0.54 10.1 2.7 2.7 2 1 1 3 3 3 0 STAT protein, all-alpha domain ABC_tran_CTD PF16326.5 CCC67210.1 - 0.094 13.0 0.2 0.094 13.0 0.2 3.3 3 1 0 3 3 3 0 ABC transporter C-terminal domain DUF1664 PF07889.12 CCC67210.1 - 0.25 11.4 6.6 0.38 10.8 0.6 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Syntaxin-6_N PF09177.11 CCC67210.1 - 0.35 11.5 17.2 0.57 10.8 1.2 3.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Fibin PF15819.5 CCC67210.1 - 0.46 10.2 4.7 0.26 11.0 2.4 1.8 1 1 1 2 2 2 0 Fin bud initiation factor homologue DUF4298 PF14131.6 CCC67210.1 - 0.46 10.5 6.1 0.24 11.4 0.5 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4298) TMF_TATA_bd PF12325.8 CCC67210.1 - 0.62 10.3 11.8 3 8.1 0.2 4.0 1 1 0 4 4 4 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.9 CCC67210.1 - 2.3 8.6 14.6 5.2 7.4 0.2 4.7 2 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 CCC67210.1 - 2.4 8.7 10.4 2.7 8.5 0.9 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF5344 PF17279.2 CCC67210.1 - 9.6 6.9 10.8 1.3 9.7 1.3 3.3 2 1 1 3 3 3 0 Family of unknown function (DUF5344) Cation_ATPase_C PF00689.21 CCC67211.1 - 3.7e-43 147.4 6.3 3.7e-43 147.4 6.3 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 CCC67211.1 - 1.2e-38 132.4 0.6 1.2e-38 132.4 0.6 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 CCC67211.1 - 1.5e-16 60.2 0.0 3.4e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCC67211.1 - 3.3e-16 60.2 0.1 2.2e-15 57.5 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCC67211.1 - 9.6e-09 34.8 0.0 3.5e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCC67211.1 - 0.00095 19.0 3.7 0.0016 18.3 0.4 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2207 PF09972.9 CCC67211.1 - 0.75 8.5 5.1 4.9 5.8 0.3 2.9 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) E1-E2_ATPase PF00122.20 CCC67212.1 - 5e-47 159.8 3.7 5e-47 159.8 3.7 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CCC67212.1 - 9.1e-19 68.6 0.1 2.2e-18 67.3 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCC67212.1 - 7.6e-11 41.5 0.3 2e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCC67212.1 - 0.002 17.9 0.1 0.0036 17.1 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCC67212.1 - 0.0028 17.7 0.0 0.0053 16.8 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) SIS_2 PF13580.6 CCC67212.1 - 0.019 15.0 0.0 0.3 11.1 0.0 2.5 2 0 0 2 2 2 0 SIS domain PUF PF00806.19 CCC67213.1 - 6.1e-66 214.6 16.6 5.7e-09 35.2 0.3 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 CCC67213.1 - 0.0015 18.9 0.8 1.4 9.2 0.1 3.6 2 2 1 3 3 3 2 CPL (NUC119) domain Inositol_P PF00459.25 CCC67214.1 - 7.5e-67 225.7 0.0 8.2e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_M1 PF01433.20 CCC67215.1 - 1.8e-87 292.5 3.2 3.4e-87 291.6 2.2 1.9 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CCC67215.1 - 6.5e-78 262.5 0.2 1.5e-75 254.7 0.0 2.3 2 0 0 2 2 2 2 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CCC67215.1 - 1e-49 169.2 4.3 1.7e-49 168.5 4.3 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain MFS_1 PF07690.16 CCC67216.1 - 5.2e-36 124.3 28.1 5.2e-36 124.3 28.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC67216.1 - 3.8e-05 22.8 29.4 0.00094 18.1 29.9 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter FSH1 PF03959.13 CCC67217.1 - 1.4e-65 220.9 0.0 1.6e-65 220.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CCC67217.1 - 0.00058 19.7 1.1 1.1 9.0 0.5 2.7 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase BAAT_C PF08840.11 CCC67217.1 - 0.0019 18.2 0.1 0.32 10.9 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 CCC67217.1 - 0.018 14.7 0.0 1.1 8.9 0.0 2.8 3 0 0 3 3 3 0 alpha/beta hydrolase fold DUF915 PF06028.11 CCC67217.1 - 0.058 12.7 0.1 0.13 11.6 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Nramp PF01566.18 CCC67218.1 - 8.6e-94 314.4 12.9 1.4e-93 313.8 12.9 1.3 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein COX5A PF02284.16 CCC67219.1 - 5.2e-40 135.6 1.3 6.7e-40 135.3 1.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va Elf1 PF05129.13 CCC67220.1 - 1.1e-30 105.5 2.4 1.4e-30 105.1 2.4 1.2 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like IMUP PF15761.5 CCC67220.1 - 0.0024 18.5 1.1 0.0047 17.6 1.1 1.6 1 0 0 1 1 1 1 Immortalisation up-regulated protein Ribosomal_L37ae PF01780.19 CCC67220.1 - 0.055 13.5 1.5 0.097 12.8 1.5 1.3 1 0 0 1 1 1 0 Ribosomal L37ae protein family Ribosomal_L1 PF00687.21 CCC67221.1 - 2.9e-37 128.4 6.1 2.9e-37 128.4 6.1 2.0 2 2 1 3 3 3 1 Ribosomal protein L1p/L10e family GCR1_C PF12550.8 CCC67222.1 - 1.4e-08 35.0 0.1 3.9e-08 33.5 0.1 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Coatomer_b_Cpla PF14806.6 CCC67222.1 - 0.039 13.9 1.9 0.097 12.7 1.9 1.6 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Aldo_ket_red PF00248.21 CCC67224.1 - 1.3e-41 142.7 0.0 2.4e-41 141.9 0.0 1.4 1 1 0 1 1 1 1 Aldo/keto reductase family PIF1 PF05970.14 CCC67225.1 - 1.9e-52 178.7 2.8 6.6e-50 170.3 2.8 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.6 CCC67225.1 - 5e-20 72.0 0.1 1e-19 71.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 CCC67225.1 - 8.2e-11 42.4 0.0 1.9e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCC67225.1 - 0.00019 21.0 1.6 0.00026 20.6 0.3 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 CCC67225.1 - 0.00053 20.3 0.0 0.0019 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CCC67225.1 - 0.002 18.6 0.1 0.0071 16.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 CCC67225.1 - 0.0049 16.0 0.7 0.011 14.8 0.7 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SH3_13 PF18335.1 CCC67225.1 - 0.0074 16.1 0.0 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain AAA_14 PF13173.6 CCC67225.1 - 0.013 15.6 0.0 0.092 12.8 0.0 2.6 1 1 0 1 1 1 0 AAA domain PhoH PF02562.16 CCC67225.1 - 0.022 14.2 0.0 0.054 12.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_10 PF12846.7 CCC67225.1 - 0.038 12.9 0.0 0.084 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain DUF2075 PF09848.9 CCC67225.1 - 0.04 13.2 0.0 0.089 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FtsK_SpoIIIE PF01580.18 CCC67225.1 - 0.054 12.8 0.3 0.12 11.7 0.1 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family UvrD_C_2 PF13538.6 CCC67225.1 - 0.1 12.4 1.7 0.55 10.1 0.3 2.7 2 1 0 2 2 2 0 UvrD-like helicase C-terminal domain ABC_tran PF00005.27 CCC67225.1 - 0.11 13.0 1.3 0.45 11.0 0.1 2.4 2 1 0 3 3 3 0 ABC transporter Sigma54_activat PF00158.26 CCC67225.1 - 0.14 11.8 0.2 0.92 9.2 0.1 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 CCC67225.1 - 0.16 11.3 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Pkinase PF00069.25 CCC67226.1 - 3.5e-65 220.0 0.5 1.2e-64 218.2 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67226.1 - 6e-31 107.7 0.4 1e-30 106.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Spt20 PF12090.8 CCC67226.1 - 0.00033 20.3 12.5 0.00055 19.6 12.5 1.3 1 0 0 1 1 1 1 Spt20 family Haspin_kinase PF12330.8 CCC67226.1 - 0.0042 16.1 3.4 0.006 15.6 0.1 2.3 2 1 0 2 2 2 1 Haspin like kinase domain Prok-TraM PF09228.10 CCC67226.1 - 0.018 15.4 1.2 0.89 10.0 0.7 2.6 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM SUIM_assoc PF16619.5 CCC67226.1 - 0.022 14.8 9.9 0.044 13.8 9.9 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 CCC67226.1 - 0.035 15.0 0.0 0.15 13.0 0.0 2.1 1 0 0 1 1 1 0 WD domain, G-beta repeat APH PF01636.23 CCC67226.1 - 0.043 13.7 0.8 0.16 11.8 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Dna2 PF08696.11 CCC67226.1 - 0.14 12.0 2.8 0.23 11.2 2.8 1.3 1 0 0 1 1 1 0 DNA replication factor Dna2 Roughex PF06020.11 CCC67226.1 - 0.31 10.1 5.9 0.47 9.5 5.9 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PhzC-PhzF PF02567.16 CCC67227.1 - 4.6e-55 187.1 0.0 5.7e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.11 CCC67227.1 - 0.0043 16.2 0.0 0.016 14.3 0.0 1.8 1 1 1 2 2 2 1 Proline racemase Pro_isomerase PF00160.21 CCC67228.1 - 1.1e-46 159.0 0.2 1.3e-46 158.8 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4134 PF13572.6 CCC67228.1 - 0.1 12.9 0.0 0.2 12.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4134) Zn_clus PF00172.18 CCC67229.1 - 1.4e-08 34.7 8.4 2.5e-08 33.9 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RPN1_RPN2_N PF17781.1 CCC67230.1 - 2.4e-112 375.3 1.5 3.4e-112 374.8 1.0 1.5 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 CCC67230.1 - 2.6e-28 97.8 0.1 5.2e-28 96.8 0.1 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 CCC67230.1 - 3.6e-27 93.4 14.9 5.2e-08 32.9 0.3 8.4 9 0 0 9 9 9 5 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CCC67230.1 - 0.00014 22.2 0.4 2.3 8.7 0.0 4.3 4 1 1 5 5 5 2 HEAT repeats Neur_chan_memb PF02932.16 CCC67230.1 - 0.23 11.5 2.4 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ATP-synt_C PF00137.21 CCC67231.1 - 9.3e-23 80.3 40.5 1.2e-16 60.8 12.3 2.7 3 0 0 3 3 3 2 ATP synthase subunit C GHMP_kinases_N PF00288.26 CCC67232.1 - 8.3e-11 42.0 0.0 1.8e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCC67232.1 - 0.00011 22.4 0.0 0.00032 21.0 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M16_C PF05193.21 CCC67233.1 - 1e-47 162.5 0.0 2.4e-47 161.3 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCC67233.1 - 2.8e-45 153.9 0.1 2.7e-43 147.5 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) AAA_5 PF07728.14 CCC67233.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Myosin_head PF00063.21 CCC67234.1 - 7.8e-269 893.5 19.2 7.8e-269 893.5 19.2 3.4 3 1 0 3 3 3 1 Myosin head (motor domain) Myosin_N PF02736.19 CCC67234.1 - 0.0097 15.7 0.3 0.053 13.4 0.3 2.3 1 1 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_16 PF13191.6 CCC67234.1 - 0.037 14.4 1.6 0.3 11.4 0.0 3.4 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 CCC67234.1 - 0.14 12.5 4.3 0.33 11.2 0.0 4.0 3 0 0 3 3 3 0 AAA domain F-box PF00646.33 CCC67235.1 - 0.09 12.7 0.0 0.35 10.8 0.0 2.0 1 0 0 1 1 1 0 F-box domain Ras PF00071.22 CCC67236.1 - 2.4e-20 72.8 0.7 1.1e-15 57.6 0.6 2.3 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CCC67236.1 - 1.1e-07 32.1 0.0 0.013 15.7 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CCC67236.1 - 0.00012 21.5 0.7 0.011 15.1 1.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCC67236.1 - 0.00015 21.4 0.0 0.0083 15.7 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CCC67236.1 - 0.0005 19.8 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation zinc_ribbon_6 PF14599.6 CCC67236.1 - 0.025 14.6 2.0 2.5 8.2 0.0 3.0 3 0 0 3 3 3 0 Zinc-ribbon Ribosomal_S27e PF01667.17 CCC67237.1 - 1.6e-29 101.4 3.5 2.1e-29 101.0 3.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.21 CCC67237.1 - 0.0099 16.1 0.8 0.011 15.9 0.8 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 CCC67237.1 - 0.024 14.2 4.2 0.035 13.6 4.2 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-ACC PF17848.1 CCC67237.1 - 3.2 7.9 6.4 19 5.4 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain NIF PF03031.18 CCC67238.1 - 8.6e-53 178.3 0.0 1.4e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Abhydro_lipase PF04083.16 CCC67239.1 - 2.3e-16 59.1 0.0 4.3e-16 58.2 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CCC67239.1 - 6.4e-08 32.6 0.1 1.5e-07 31.3 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCC67239.1 - 9.5e-06 25.0 0.0 3.9e-05 23.1 0.0 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase_2 PF01674.18 CCC67239.1 - 0.0016 18.0 0.0 0.0031 17.1 0.0 1.5 1 1 0 1 1 1 1 Lipase (class 2) DUF900 PF05990.12 CCC67239.1 - 0.006 16.1 0.0 0.0097 15.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PUF PF00806.19 CCC67240.1 - 4.8e-57 186.6 16.0 2.6e-07 30.0 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Rab5ip PF07019.12 CCC67241.1 - 2.1e-22 79.5 3.9 2.5e-22 79.2 3.9 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF383 PF04063.14 CCC67242.1 - 3.9e-62 209.3 0.5 4.2e-61 206.0 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 CCC67242.1 - 1e-20 73.3 1.7 1.2e-20 73.1 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF384) RXT2_N PF08595.11 CCC67242.1 - 0.21 11.6 3.1 0.52 10.3 3.1 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.12 CCC67242.1 - 1.5 8.5 10.6 2.8 7.6 10.6 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2457 PF10446.9 CCC67242.1 - 1.8 7.6 15.3 2.5 7.1 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.12 CCC67242.1 - 2.1 7.6 14.0 0.076 12.3 8.0 1.6 2 0 0 2 2 2 0 NOA36 protein DNA_pol_phi PF04931.13 CCC67242.1 - 9.6 4.2 16.2 0.08 11.0 7.4 2.1 3 0 0 3 3 3 0 DNA polymerase phi TFIIF_alpha PF05793.12 CCC67243.1 - 3.6e-10 39.1 0.8 3.6e-10 39.1 0.8 3.0 3 1 1 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-UBR PF02207.20 CCC67244.1 - 1.8e-16 60.0 15.7 1.8e-16 60.0 15.7 2.5 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.17 CCC67244.1 - 3.4e-05 23.5 0.1 9.2e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.6 CCC67244.1 - 0.00036 20.8 1.0 0.00036 20.8 1.0 3.3 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.7 CCC67244.1 - 0.013 15.8 0.4 0.013 15.8 0.4 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CCC67244.1 - 0.043 13.7 4.0 0.022 14.6 0.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF3685 PF12452.8 CCC67244.1 - 0.86 9.3 3.5 18 5.0 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) UCR_UQCRX_QCR9 PF05365.12 CCC67245.1 - 8.8e-28 96.0 3.4 9.9e-28 95.9 3.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like zf-Tim10_DDP PF02953.15 CCC67246.1 - 5.6e-19 67.5 2.1 7.9e-19 67.1 2.1 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribonuc_red_sm PF00268.21 CCC67247.1 - 5.4e-84 281.9 1.5 6.6e-84 281.7 1.5 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain KLRAQ PF10205.9 CCC67248.1 - 0.097 12.9 5.9 3.5 7.9 1.4 2.6 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Atg14 PF10186.9 CCC67248.1 - 0.32 10.0 8.9 0.49 9.4 8.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 CCC67248.1 - 0.5 10.7 7.7 0.2 12.0 3.4 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) LsmAD PF06741.13 CCC67249.1 - 2.4e-29 101.7 0.4 2.4e-29 101.7 0.4 2.5 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 CCC67249.1 - 3.5e-18 65.5 0.4 3e-17 62.5 0.0 2.4 2 0 0 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.7 CCC67249.1 - 0.0019 18.2 0.1 0.0043 17.1 0.1 1.7 1 1 0 1 1 1 1 Scd6-like Sm domain AATase PF07247.12 CCC67250.1 - 9.8e-153 509.3 1.4 1.1e-152 509.1 1.4 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Chordopox_A15 PF05846.12 CCC67250.1 - 0.0071 16.5 0.2 0.025 14.8 0.1 1.9 2 0 0 2 2 2 1 Chordopoxvirus A15 protein SE PF08491.10 CCC67251.1 - 5.6e-121 402.8 0.0 7.3e-121 402.4 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 CCC67251.1 - 6.1e-11 42.2 0.0 1.4e-10 40.9 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCC67251.1 - 1.7e-05 24.6 0.1 0.00019 21.2 0.2 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 CCC67251.1 - 0.0028 18.2 1.7 0.0055 17.2 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCC67251.1 - 0.0051 16.1 0.1 0.0083 15.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 CCC67251.1 - 0.0058 16.8 0.1 0.013 15.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CCC67251.1 - 0.012 14.7 0.9 0.02 14.0 0.9 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 CCC67251.1 - 0.015 14.5 0.3 0.036 13.3 0.1 1.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CCC67251.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 CCC67251.1 - 0.028 13.8 0.5 0.049 13.0 0.5 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CCC67251.1 - 0.029 14.3 0.2 0.045 13.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.14 CCC67251.1 - 0.17 10.5 1.4 1.6 7.4 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein CBP4 PF07960.11 CCC67252.1 - 3e-56 188.8 0.9 3.5e-56 188.6 0.9 1.0 1 0 0 1 1 1 1 CBP4 DUF4574 PF15141.6 CCC67252.1 - 0.00037 20.4 0.6 0.00097 19.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquinol-cytochrome-c reductase complex assembly factor 3 DUF600 PF04634.12 CCC67252.1 - 0.032 14.3 0.1 0.076 13.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF600 LAMTOR PF15454.6 CCC67252.1 - 0.076 13.6 4.2 0.13 12.9 0.6 2.2 2 0 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF737 PF05300.11 CCC67252.1 - 0.92 9.8 8.2 1 9.6 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF737) Jnk-SapK_ap_N PF09744.9 CCC67252.1 - 4.8 7.4 12.0 41 4.4 11.7 2.0 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Flavodoxin_2 PF02525.17 CCC67253.1 - 1.6e-56 191.2 0.0 1.9e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCC67253.1 - 9.8e-14 51.4 0.0 1.7e-13 50.6 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CCC67254.1 - 6e-39 133.8 0.0 7.2e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCC67254.1 - 4e-05 23.4 0.0 0.00044 20.0 0.0 2.2 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Yip1 PF04893.17 CCC67255.1 - 4.6e-14 52.5 12.6 6.6e-14 52.0 12.6 1.3 1 0 0 1 1 1 1 Yip1 domain tRNA-synt_1g PF09334.11 CCC67256.1 - 1.2e-87 294.2 0.1 4.7e-86 289.0 0.1 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 CCC67256.1 - 7.7e-23 80.6 0.0 9.2e-10 37.4 0.0 3.7 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CCC67256.1 - 3.5e-06 26.6 0.0 0.00042 19.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain PS_Dcarbxylase PF02666.15 CCC67257.1 - 2.2e-53 180.8 0.0 4.6e-53 179.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 CCC67257.1 - 1.3e-17 63.9 2.8 4.8e-11 42.8 0.0 3.2 3 0 0 3 3 3 2 C2 domain PseudoU_synth_2 PF00849.22 CCC67258.1 - 4.8e-26 91.7 0.0 9.9e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase ATP_synt_H PF05493.13 CCC67259.1 - 4.3e-20 71.9 4.5 4.9e-20 71.7 4.5 1.0 1 0 0 1 1 1 1 ATP synthase subunit H AzlD PF05437.12 CCC67259.1 - 0.026 14.7 2.9 0.039 14.1 0.1 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) TMEM220 PF15071.6 CCC67259.1 - 0.03 15.1 0.6 0.035 14.8 0.6 1.2 1 0 0 1 1 1 0 Transmembrane family 220, helix DUF3792 PF12670.7 CCC67259.1 - 0.036 14.2 1.4 0.041 14.0 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3792) Glucos_trans_II PF14264.6 CCC67259.1 - 0.061 12.7 2.4 0.063 12.6 2.4 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII DUF3624 PF12292.8 CCC67259.1 - 0.08 13.4 2.1 0.12 12.8 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3624) Renin_r PF07850.14 CCC67259.1 - 0.17 12.5 0.8 0.32 11.6 0.1 1.7 1 1 1 2 2 2 0 Renin receptor-like protein Clathrin_lg_ch PF01086.17 CCC67261.1 - 4.3e-56 190.5 24.7 4.9e-56 190.4 24.7 1.0 1 0 0 1 1 1 1 Clathrin light chain SMBP PF16785.5 CCC67261.1 - 0.0013 19.0 0.4 0.0026 18.0 0.4 1.5 1 0 0 1 1 1 1 Small metal-binding protein Trs65 PF12735.7 CCC67262.1 - 5.7e-36 124.5 6.5 4.2e-34 118.4 6.5 2.3 1 1 0 1 1 1 1 TRAPP trafficking subunit Trs65 Bot1p PF12298.8 CCC67263.1 - 2.1e-64 216.9 0.2 2.1e-64 216.9 0.2 1.5 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Cas9_Topo PF17894.1 CCC67263.1 - 0.079 13.0 0.0 0.26 11.4 0.0 1.8 1 0 0 1 1 1 0 Topo homolgy domain in CRISPR-associated endonuclease Cas9 Vitelline_membr PF10542.9 CCC67263.1 - 0.25 11.2 0.8 2 8.3 0.1 2.4 2 0 0 2 2 2 0 Vitelline membrane cysteine-rich region Sad1_UNC PF07738.13 CCC67264.1 - 1.8e-07 31.2 1.2 4.3e-05 23.5 0.1 3.0 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal GAT PF03127.14 CCC67264.1 - 0.037 14.3 0.9 0.037 14.3 0.9 3.1 3 1 0 3 3 3 0 GAT domain Cpn60_TCP1 PF00118.24 CCC67265.1 - 3.4e-163 543.8 5.7 3.9e-163 543.6 5.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NusA_N PF08529.11 CCC67265.1 - 0.066 13.6 0.2 0.21 12.0 0.2 1.9 1 0 0 1 1 1 0 NusA N-terminal domain Mad3_BUB1_I PF08311.12 CCC67266.1 - 1.7e-32 112.0 0.2 4.7e-32 110.6 0.2 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 CCC67266.1 - 3.7e-26 91.1 0.2 8.4e-26 89.9 0.2 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase PF00069.25 CCC67266.1 - 4.2e-16 59.1 0.0 1.2e-15 57.7 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67266.1 - 6.8e-06 25.6 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_I_2 PF17014.5 CCC67266.1 - 5.3e-05 23.3 0.5 0.00036 20.6 0.1 2.4 2 0 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein Kinase-like PF14531.6 CCC67266.1 - 0.053 12.8 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MMR_HSR1_Xtn PF16897.5 CCC67267.1 - 9.1e-37 125.3 1.1 1.9e-36 124.3 1.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 CCC67267.1 - 9.5e-22 77.2 0.1 2.2e-21 76.0 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CCC67267.1 - 1.9e-19 69.5 0.0 3.7e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CCC67267.1 - 5.8e-13 48.7 0.0 1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CCC67267.1 - 0.00024 21.2 0.4 0.097 12.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 CCC67267.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.10 CCC67267.1 - 0.008 15.6 0.3 0.098 12.1 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MCM PF00493.23 CCC67267.1 - 0.018 14.1 0.1 0.093 11.8 0.0 2.0 2 0 0 2 2 2 0 MCM P-loop domain Roc PF08477.13 CCC67267.1 - 0.036 14.3 0.8 0.14 12.4 0.1 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CCC67267.1 - 0.085 13.2 0.2 0.16 12.3 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 CCC67267.1 - 0.085 12.4 0.4 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 Ras family DUF1178 PF06676.11 CCC67267.1 - 0.086 13.2 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) Amidohydro_1 PF01979.20 CCC67267.1 - 0.14 11.4 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family RsgA_GTPase PF03193.16 CCC67267.1 - 0.42 10.5 2.0 2 8.3 0.2 2.7 2 1 1 3 3 3 0 RsgA GTPase Glyco_hydro_16 PF00722.21 CCC67268.1 - 5.1e-44 149.8 0.6 5.1e-44 149.8 0.6 2.4 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Dicty_REP PF05086.12 CCC67268.1 - 1.6 6.6 17.0 2.1 6.2 17.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SOG2 PF10428.9 CCC67268.1 - 4.8 6.3 31.9 6.5 5.8 31.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein AA_permease PF00324.21 CCC67269.1 - 9.1e-137 456.5 32.4 1.1e-136 456.2 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC67269.1 - 3.4e-36 125.0 36.6 4.2e-36 124.7 36.6 1.0 1 0 0 1 1 1 1 Amino acid permease UPF0139 PF03669.13 CCC67269.1 - 4.7 7.1 7.5 0.34 10.8 0.3 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0139) DUF5316 PF17247.2 CCC67270.1 - 0.04 13.9 0.5 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5316) Nucleo_P87 PF07267.11 CCC67270.1 - 0.083 11.7 1.9 0.11 11.4 1.9 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PP1 PF07430.11 CCC67270.1 - 0.13 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Phloem filament protein PP1 cystatin-like domain DUF2304 PF10066.9 CCC67270.1 - 0.21 11.8 5.0 0.11 12.7 3.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) DUF2207 PF09972.9 CCC67270.1 - 0.26 10.0 0.0 0.26 10.0 0.0 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.8 CCC67270.1 - 0.35 10.8 6.4 9.8 6.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) DUF5345 PF17280.2 CCC67270.1 - 0.55 10.3 0.0 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF2116 PF09889.9 CCC67270.1 - 0.98 9.4 0.0 0.98 9.4 0.0 2.1 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) EIF_2_alpha PF07541.12 CCC67271.1 - 2e-38 131.0 0.2 4.7e-38 129.8 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CCC67271.1 - 2.1e-14 53.6 1.0 4.9e-14 52.4 1.0 1.6 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.9 CCC67271.1 - 0.22 12.1 2.6 0.22 12.1 0.3 2.1 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 Gp_dh_C PF02800.20 CCC67272.1 - 9.4e-73 243.0 0.2 2.4e-72 241.7 0.1 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CCC67272.1 - 1.8e-39 134.1 0.0 4.5e-39 132.9 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CCC67272.1 - 0.025 14.7 1.1 0.061 13.5 0.2 2.3 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Biotin_lipoyl PF00364.22 CCC67273.1 - 2.6e-20 72.0 0.6 5.9e-20 70.9 0.6 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 CCC67273.1 - 0.00038 20.7 0.1 0.00092 19.5 0.1 1.7 1 0 0 1 1 1 1 e3 binding domain Bot1p PF12298.8 CCC67273.1 - 0.067 13.4 2.0 9.2 6.4 0.0 2.6 2 1 0 2 2 2 0 Eukaryotic mitochondrial regulator protein WD40_like PF17005.5 CCC67274.1 - 3.4e-07 29.9 0.6 0.27 10.5 0.0 3.4 2 1 2 4 4 4 3 WD40-like domain WD40 PF00400.32 CCC67274.1 - 4.6e-06 27.3 0.7 0.00016 22.4 0.0 3.4 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC67274.1 - 0.00012 22.3 0.1 0.011 16.1 0.0 3.3 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain MMS1_N PF10433.9 CCC67274.1 - 0.0042 15.8 0.4 7.5 5.0 0.1 3.1 2 1 1 3 3 3 3 Mono-functional DNA-alkylating methyl methanesulfonate N-term Cytochrom_D1 PF02239.16 CCC67274.1 - 0.016 13.8 0.0 0.24 9.9 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain FGGY_N PF00370.21 CCC67275.1 - 4.4e-21 75.6 0.0 7.6e-12 45.3 0.0 2.6 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 CCC67275.1 - 1.8e-15 57.2 0.0 3.9e-14 52.8 0.0 2.4 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF3533 PF12051.8 CCC67277.1 - 3.4e-124 414.6 15.6 3.4e-124 414.6 15.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.12 CCC67277.1 - 0.05 13.5 0.2 0.05 13.5 0.2 2.5 2 1 0 2 2 2 0 CDR ABC transporter TPR_2 PF07719.17 CCC67278.1 - 1.5e-05 24.8 12.6 0.13 12.4 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCC67278.1 - 0.00011 22.1 13.5 0.85 10.0 0.2 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCC67278.1 - 0.00069 19.3 7.8 1.5 8.8 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 CCC67278.1 - 0.0077 16.5 1.9 28 5.1 0.0 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC67278.1 - 0.21 11.9 11.5 4.1 7.7 1.0 4.6 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CCC67278.1 - 0.95 9.2 0.0 0.95 9.2 0.0 3.6 4 0 0 4 4 4 0 TPR repeat Epimerase PF01370.21 CCC67279.1 - 1.1e-19 70.9 0.0 1.5e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCC67279.1 - 5.5e-13 48.6 0.1 7.4e-13 48.1 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CCC67279.1 - 1.1e-08 34.6 0.0 1.1e-07 31.4 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 CCC67279.1 - 7e-07 29.0 0.3 2.5e-06 27.1 0.3 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 CCC67279.1 - 1.8e-06 27.5 0.1 0.00035 20.1 0.0 2.4 2 0 0 2 2 2 2 short chain dehydrogenase NAD_binding_10 PF13460.6 CCC67279.1 - 2e-06 27.8 0.0 3.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CCC67279.1 - 0.00081 19.0 0.6 0.076 12.6 0.1 2.9 3 1 0 3 3 3 1 NmrA-like family Polysacc_synt_2 PF02719.15 CCC67279.1 - 0.0016 17.6 0.2 0.012 14.7 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DapB_N PF01113.20 CCC67279.1 - 0.12 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.20 CCC67279.1 - 0.12 12.4 0.1 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3533 PF12051.8 CCC67280.1 - 1.5e-111 373.0 22.7 1.9e-111 372.7 22.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.12 CCC67280.1 - 0.13 12.2 0.0 0.13 12.2 0.0 2.5 4 0 0 4 4 4 0 CDR ABC transporter tRNA_SAD PF07973.14 CCC67282.1 - 1.4e-06 28.2 0.3 4.6e-06 26.6 0.3 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.19 CCC67282.1 - 1.3e-05 24.0 0.1 2.9e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 tRNA synthetases class II (A) Med2 PF11214.8 CCC67282.1 - 0.012 15.8 0.1 0.028 14.5 0.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 PMT PF02366.18 CCC67284.1 - 3.4e-88 295.4 20.5 3.4e-88 295.4 20.5 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCC67284.1 - 6.5e-57 192.4 14.0 6.5e-57 192.4 14.0 2.6 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCC67284.1 - 7.7e-23 81.3 0.4 1.5e-22 80.3 0.4 1.4 1 0 0 1 1 1 1 MIR domain WD40 PF00400.32 CCC67285.1 - 3.9e-37 125.6 26.1 9.4e-08 32.6 0.0 11.7 12 0 0 12 12 12 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC67285.1 - 6.7e-12 45.5 2.1 4 7.8 0.0 8.2 5 4 4 9 9 9 5 Anaphase-promoting complex subunit 4 WD40 domain YmzC PF14157.6 CCC67285.1 - 0.059 13.5 0.1 39 4.4 0.0 3.6 4 0 0 4 4 4 0 YmzC-like protein Peptidase_C101 PF16218.5 CCC67285.1 - 0.07 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C101 Rhodanese PF00581.20 CCC67286.1 - 2.1e-10 41.1 0.1 2.6e-10 40.7 0.1 1.2 1 0 0 1 1 1 1 Rhodanese-like domain FTHFS PF01268.19 CCC67287.1 - 4.2e-253 840.6 0.3 6.4e-253 840.0 0.3 1.3 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CCC67287.1 - 3.3e-62 208.5 2.2 4.8e-62 208.0 0.2 2.3 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CCC67287.1 - 3.5e-39 133.7 0.9 8.4e-39 132.4 0.9 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.21 CCC67287.1 - 0.0019 18.3 0.3 0.11 12.6 0.3 2.9 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Helicase_C_4 PF13871.6 CCC67287.1 - 0.0046 16.7 0.0 0.008 15.9 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue CbiA PF01656.23 CCC67287.1 - 0.0049 16.9 0.0 0.16 12.0 0.0 3.0 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AlaDh_PNT_C PF01262.21 CCC67287.1 - 0.0061 15.9 0.1 0.013 14.8 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.20 CCC67287.1 - 0.066 13.3 0.4 0.79 9.8 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_3_C PF01915.22 CCC67287.1 - 0.096 12.6 0.4 2.9 7.8 0.0 2.7 3 0 0 3 3 3 0 Glycosyl hydrolase family 3 C-terminal domain GTP_EFTU PF00009.27 CCC67287.1 - 0.12 11.9 0.5 0.27 10.8 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRP54 PF00448.22 CCC67288.1 - 0.002 17.8 0.0 0.0027 17.4 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CCC67288.1 - 0.0024 18.3 0.0 0.004 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CCC67288.1 - 0.004 17.7 0.1 0.0094 16.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CCC67288.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 CCC67288.1 - 0.039 14.2 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CCC67288.1 - 0.05 14.0 0.0 0.15 12.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase ResIII PF04851.15 CCC67288.1 - 0.077 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.14 CCC67288.1 - 0.11 11.7 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_14 PF13173.6 CCC67288.1 - 0.11 12.5 0.1 0.32 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain Collagen PF01391.18 CCC67289.1 - 1.1e-08 34.6 56.3 2.7e-06 27.1 26.8 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Glutenin_hmw PF03157.13 CCC67289.1 - 0.042 12.3 35.7 0.059 11.8 35.7 1.1 1 0 0 1 1 1 0 High molecular weight glutenin subunit Plasmodium_HRP PF05403.11 CCC67289.1 - 0.39 10.5 4.2 0.56 10.0 4.2 1.1 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) Mvb12 PF09452.10 CCC67290.1 - 1.1e-37 128.3 0.4 1.5e-37 127.8 0.4 1.2 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 Peptidase_S80 PF07230.11 CCC67290.1 - 0.18 10.1 0.0 0.23 9.7 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) ETF PF01012.21 CCC67291.1 - 5.6e-37 127.4 0.0 7.3e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain Hydrolase PF00702.26 CCC67292.1 - 1.2e-15 58.4 0.4 1.8e-15 57.8 0.4 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CCC67292.1 - 6.4e-14 52.8 0.0 1.1e-13 52.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CCC67292.1 - 1.8e-09 37.7 0.0 9.8e-08 32.0 0.0 2.9 1 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCC67292.1 - 3e-05 24.2 0.2 0.0019 18.3 0.2 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.12 CCC67292.1 - 0.0077 15.7 0.0 0.012 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) S6PP PF05116.13 CCC67292.1 - 0.11 12.0 0.0 0.59 9.6 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase TetR_C_3 PF08362.11 CCC67292.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region Thioredoxin PF00085.20 CCC67293.1 - 1.3e-30 105.4 0.5 1.8e-30 104.9 0.5 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 CCC67293.1 - 1.5e-07 31.3 0.1 1.9e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CCC67293.1 - 4.3e-06 27.1 0.3 3.3e-05 24.3 0.3 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 CCC67293.1 - 1.2e-05 25.5 0.1 6.6e-05 23.2 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 CCC67293.1 - 4.4e-05 23.4 0.2 5.9e-05 23.0 0.2 1.1 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.16 CCC67293.1 - 9.7e-05 22.2 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 OST3_OST6 PF04756.13 CCC67293.1 - 0.0011 18.5 0.2 0.0011 18.3 0.2 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Redoxin PF08534.10 CCC67293.1 - 0.002 17.8 0.1 0.0024 17.6 0.1 1.2 1 0 0 1 1 1 1 Redoxin TraF PF13728.6 CCC67293.1 - 0.0063 16.4 0.1 0.0083 16.0 0.1 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.11 CCC67293.1 - 0.032 14.2 0.0 0.057 13.4 0.0 1.3 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 CCC67293.1 - 0.035 14.3 0.2 0.066 13.4 0.2 1.5 1 1 0 1 1 1 0 Thioredoxin-like MMR_HSR1_C PF08438.10 CCC67294.1 - 1.7e-36 125.2 0.0 2.7e-36 124.6 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 CCC67294.1 - 1.1e-19 70.6 0.0 2.5e-19 69.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCC67294.1 - 3e-07 30.1 0.0 1.1e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CCC67294.1 - 0.00077 19.0 0.1 0.31 10.6 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 CCC67294.1 - 0.01 15.9 0.1 0.054 13.5 0.0 2.2 3 0 0 3 3 3 0 Dynamin family RsgA_GTPase PF03193.16 CCC67294.1 - 0.014 15.3 1.3 0.36 10.7 0.1 2.6 3 0 0 3 3 3 0 RsgA GTPase ATP_bind_1 PF03029.17 CCC67294.1 - 0.02 14.7 0.1 3.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 CCC67294.1 - 0.042 13.2 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 CCC67294.1 - 0.13 12.0 0.2 6.1 6.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain KTI12 PF08433.10 CCC67294.1 - 0.18 11.2 0.1 0.45 9.9 0.0 1.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 RSF PF14876.6 CCC67295.1 - 7.7e-12 44.9 2.3 7.7e-12 44.9 2.3 2.1 1 1 0 2 2 2 1 Respiratory growth transcriptional regulator Cwf_Cwc_15 PF04889.12 CCC67295.1 - 5.1 6.8 31.1 1.4 8.6 23.3 2.5 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein zf-ZPR1 PF03367.13 CCC67296.1 - 1.5e-116 385.7 3.1 5.4e-58 195.4 0.3 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 CCC67296.1 - 0.00069 19.6 3.6 0.4 10.7 0.1 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FragX_IP PF05994.11 CCC67296.1 - 0.041 11.9 0.1 0.061 11.4 0.1 1.1 1 0 0 1 1 1 0 Cytoplasmic Fragile-X interacting family DUF4985 PF16373.5 CCC67296.1 - 0.07 13.6 0.3 0.37 11.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function Bestrophin PF01062.21 CCC67296.1 - 0.24 10.8 0.5 2.1 7.6 0.1 2.3 2 1 1 3 3 3 0 Bestrophin, RFP-TM, chloride channel zinc-ribbons_6 PF07191.12 CCC67296.1 - 0.29 11.1 4.7 0.47 10.5 1.0 2.5 2 1 0 2 2 2 0 zinc-ribbons zf-C2HC5 PF06221.13 CCC67296.1 - 0.65 10.0 0.1 0.65 10.0 0.1 3.3 4 0 0 4 4 4 0 Putative zinc finger motif, C2HC5-type DZR PF12773.7 CCC67296.1 - 0.69 10.0 8.8 5.1 7.2 1.8 3.4 2 2 0 2 2 2 0 Double zinc ribbon zf-RRPl_C4 PF17026.5 CCC67296.1 - 1.1 9.4 4.7 4.1 7.5 1.4 2.7 2 0 0 2 2 2 0 Putative ribonucleoprotein zinc-finger pf C4 type RNHCP PF12647.7 CCC67296.1 - 1.9 8.5 7.5 1.2 9.1 1.2 3.3 4 1 1 5 5 4 0 RNHCP domain Lar_restr_allev PF14354.6 CCC67296.1 - 2.3 8.6 8.0 32 5.0 2.7 3.4 3 0 0 3 3 3 0 Restriction alleviation protein Lar zinc_ribbon_2 PF13240.6 CCC67296.1 - 3.5 7.5 13.6 4.4 7.2 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain AATase PF07247.12 CCC67297.1 - 6.3e-60 203.1 4.4 1.3e-59 202.1 4.4 1.4 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.20 CCC67297.1 - 1.2e-05 24.2 0.1 0.12 11.0 0.0 2.2 2 0 0 2 2 2 2 Condensation domain HTH_34 PF13601.6 CCC67297.1 - 0.12 12.5 0.0 0.52 10.5 0.0 1.9 2 0 0 2 2 2 0 Winged helix DNA-binding domain RTA1 PF04479.13 CCC67298.1 - 2.3e-62 210.3 12.1 2.3e-62 210.3 12.1 1.6 2 0 0 2 2 2 1 RTA1 like protein Ribosomal_S2 PF00318.20 CCC67299.1 - 4.9e-26 91.3 1.4 7.3e-14 51.5 0.0 2.3 2 1 1 3 3 3 2 Ribosomal protein S2 40S_SA_C PF16122.5 CCC67299.1 - 0.025 15.9 12.4 0.05 15.0 12.4 1.5 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus MRP-S33 PF08293.11 CCC67300.1 - 9.5e-35 118.7 0.2 1.1e-34 118.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Gpi1 PF05024.15 CCC67301.1 - 9.1e-54 182.4 16.7 9.1e-54 182.4 16.7 2.1 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Ion_trans PF00520.31 CCC67302.1 - 2.6e-99 331.4 115.0 3.9e-36 124.5 15.5 5.0 4 1 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.32 CCC67302.1 - 0.096 12.3 0.0 0.36 10.5 0.0 2.1 1 0 0 1 1 1 0 EF hand CRM1_C PF08767.11 CCC67303.1 - 3.2e-130 434.0 6.3 3.2e-130 434.0 6.3 2.8 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 CCC67303.1 - 3.2e-36 124.6 7.5 3.2e-36 124.6 7.5 3.3 4 0 0 4 4 4 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 CCC67303.1 - 6.6e-32 109.0 2.3 1.8e-31 107.6 2.3 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CCC67303.1 - 4e-28 97.3 1.5 2.4e-27 94.8 0.4 3.0 2 0 0 2 2 2 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 CCC67303.1 - 3.6e-16 58.4 0.4 3.6e-16 58.4 0.4 2.1 2 0 0 2 2 2 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 CCC67303.1 - 1.3e-14 53.9 0.6 7.2e-14 51.5 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3385 PF11865.8 CCC67303.1 - 0.0086 16.0 2.7 0.16 11.9 0.1 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) V-ATPase_H_C PF11698.8 CCC67303.1 - 0.017 15.2 3.7 0.12 12.5 0.2 3.5 3 0 0 3 3 3 0 V-ATPase subunit H FNIP_C PF14638.6 CCC67303.1 - 0.26 10.9 5.3 0.77 9.4 1.5 2.9 3 0 0 3 3 3 0 Folliculin-interacting protein C-terminus DUF507 PF04368.13 CCC67303.1 - 0.65 9.9 7.0 1.9 8.4 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF507) DrrA_P4M PF14860.6 CCC67303.1 - 5.3 7.0 6.2 10 6.0 0.2 3.9 4 0 0 4 4 4 0 DrrA phosphatidylinositol 4-phosphate binding domain Ribosomal_L3 PF00297.22 CCC67304.1 - 6.9e-16 58.2 1.9 1.4e-14 53.9 0.9 2.1 1 1 1 2 2 2 2 Ribosomal protein L3 DUF3589 PF12141.8 CCC67305.1 - 1.4e-71 241.6 7.6 1.8e-47 162.1 0.0 2.6 1 1 1 2 2 2 2 Beta-mannosyltransferases Dimer_Tnp_hAT PF05699.14 CCC67306.1 - 7.7e-09 35.2 0.1 2.8e-08 33.4 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CCC67306.1 - 0.17 12.0 0.5 0.47 10.5 0.5 1.9 1 0 0 1 1 1 0 BED zinc finger EF_assoc_2 PF08356.12 CCC67307.1 - 1.6e-26 92.1 0.1 9e-26 89.7 0.0 2.4 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.12 CCC67307.1 - 4.3e-26 90.3 1.5 6.8e-26 89.7 0.7 1.8 2 0 0 2 2 1 1 EF hand associated Ras PF00071.22 CCC67307.1 - 1.5e-24 86.5 0.0 1.1e-11 44.7 0.0 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CCC67307.1 - 9.4e-15 54.9 0.0 1.1e-07 32.0 0.0 2.7 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CCC67307.1 - 7e-09 35.8 0.0 0.00056 20.0 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 CCC67307.1 - 1.8e-07 30.2 7.9 4.4e-05 22.7 0.4 3.5 4 0 0 4 4 3 2 EF hand EF-hand_7 PF13499.6 CCC67307.1 - 4.6e-07 30.2 1.1 0.058 13.8 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCC67307.1 - 7e-07 28.7 0.9 0.00061 19.5 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain AAA_16 PF13191.6 CCC67307.1 - 2e-05 25.0 0.0 0.28 11.6 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain Dynamin_N PF00350.23 CCC67307.1 - 3.2e-05 24.1 0.0 0.018 15.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family EF-hand_8 PF13833.6 CCC67307.1 - 0.00019 21.2 1.1 0.075 12.9 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CCC67307.1 - 0.00023 20.5 3.2 0.00043 19.6 0.8 2.6 2 0 0 2 2 2 1 EF hand Arf PF00025.21 CCC67307.1 - 0.0005 19.6 0.0 0.0014 18.1 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCC67307.1 - 0.0021 17.6 0.0 3.1 7.3 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CCC67307.1 - 0.0031 17.2 0.2 3.7 7.4 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CCC67307.1 - 0.0035 17.6 0.0 0.88 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCC67307.1 - 0.0039 17.1 0.4 0.47 10.3 0.1 3.4 3 1 0 3 3 3 1 RsgA GTPase TniB PF05621.11 CCC67307.1 - 0.0048 16.3 0.0 0.043 13.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 CCC67307.1 - 0.0052 17.3 0.0 0.49 11.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.18 CCC67307.1 - 0.0095 15.5 0.1 1.5 8.3 0.0 3.3 3 0 0 3 3 3 1 Ferrous iron transport protein B ABC_tran PF00005.27 CCC67307.1 - 0.014 15.9 0.2 3.5 8.1 0.3 2.4 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 CCC67307.1 - 0.018 14.8 0.0 3.2 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CCC67307.1 - 0.029 13.6 0.0 1.7 7.8 0.0 2.2 2 0 0 2 2 2 0 Septin RNA_helicase PF00910.22 CCC67307.1 - 0.033 14.6 0.0 6.4 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.6 CCC67307.1 - 0.039 13.7 0.0 2.4 7.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain AAA_32 PF13654.6 CCC67307.1 - 0.094 11.5 0.0 1.1 8.0 0.0 2.2 2 1 1 3 3 3 0 AAA domain EF-hand_10 PF14788.6 CCC67307.1 - 0.15 12.0 0.7 2.7 7.9 0.1 2.7 2 0 0 2 2 2 0 EF hand NACHT PF05729.12 CCC67307.1 - 0.16 11.9 0.1 5.6 6.8 0.0 2.7 3 0 0 3 3 2 0 NACHT domain Mto2_bdg PF12808.7 CCC67308.1 - 3.1e-05 24.2 5.3 3.1e-05 24.2 5.3 3.7 2 1 1 3 3 3 1 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_2 PF07716.15 CCC67308.1 - 0.0067 16.5 4.1 0.0067 16.5 4.1 6.0 6 1 0 6 6 6 1 Basic region leucine zipper Peptidase_C37 PF05416.12 CCC67308.1 - 0.069 11.7 4.3 0.18 10.3 4.3 1.7 1 0 0 1 1 1 0 Southampton virus-type processing peptidase DUF948 PF06103.11 CCC67308.1 - 0.09 13.0 0.3 0.09 13.0 0.3 5.8 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) FAD-SLDH PF12318.8 CCC67308.1 - 6.4 6.8 12.2 12 6.0 0.6 4.2 3 1 1 4 4 4 0 Membrane bound FAD containing D-sorbitol dehydrogenase BolA PF01722.18 CCC67309.1 - 6.9e-11 42.3 0.0 1.6e-10 41.1 0.0 1.7 1 1 0 1 1 1 1 BolA-like protein BolA PF01722.18 CCC67310.1 - 4.6e-24 84.5 0.6 5.6e-24 84.2 0.6 1.1 1 0 0 1 1 1 1 BolA-like protein Fe_dep_repr_C PF02742.15 CCC67310.1 - 0.045 13.8 0.0 0.078 13.1 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, metal binding and dimerisation domain GCV_H PF01597.19 CCC67311.1 - 5.7e-45 152.2 0.3 6.8e-45 151.9 0.3 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 CCC67311.1 - 0.074 12.9 0.2 0.2 11.5 0.1 1.7 2 0 0 2 2 2 0 Biotin-requiring enzyme DUF3453 PF11935.8 CCC67312.1 - 1.3e-53 181.9 1.7 1.8e-53 181.5 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3453) COPIIcoated_ERV PF07970.12 CCC67313.1 - 2.1e-70 237.0 1.1 2.6e-70 236.7 1.1 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCC67313.1 - 1.1e-28 99.4 0.2 2.6e-28 98.2 0.2 1.7 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CDC24 PF06395.11 CCC67314.1 - 2.2e-35 120.8 0.8 2.2e-35 120.8 0.8 2.1 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.20 CCC67314.1 - 1e-28 100.9 3.8 1e-28 100.9 3.8 2.6 3 0 0 3 3 3 1 RhoGEF domain PH_10 PF15411.6 CCC67314.1 - 6.4e-27 94.3 5.4 1.7e-25 89.7 5.4 2.9 1 1 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.24 CCC67314.1 - 2.7e-05 24.0 0.4 6.9e-05 22.7 0.4 1.8 1 0 0 1 1 1 1 PB1 domain Laminin_II PF06009.12 CCC67314.1 - 0.062 13.3 1.7 1.3 9.1 0.0 3.3 3 0 0 3 3 3 0 Laminin Domain II PI3K_rbd PF00794.18 CCC67314.1 - 0.069 13.3 0.1 0.19 11.9 0.1 1.8 1 0 0 1 1 1 0 PI3-kinase family, ras-binding domain PH PF00169.29 CCC67314.1 - 0.096 13.2 2.0 0.72 10.4 2.0 2.5 1 1 0 1 1 1 0 PH domain Cyclin_N PF00134.23 CCC67315.1 - 1e-26 93.2 3.7 2.3e-26 92.0 3.7 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyto_heme_lyase PF01265.17 CCC67316.1 - 5.7e-93 311.7 6.9 2.1e-92 309.8 6.9 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase PK PF00224.21 CCC67317.1 - 1.8e-167 556.6 0.9 2.4e-167 556.2 0.9 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CCC67317.1 - 2.1e-33 115.0 0.0 6.9e-33 113.4 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CCC67317.1 - 1.9e-05 23.9 0.4 4.4e-05 22.7 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Sulfotransfer_1 PF00685.27 CCC67317.1 - 0.21 11.1 0.0 0.67 9.4 0.0 1.8 3 0 0 3 3 3 0 Sulfotransferase domain EF_assoc_2 PF08356.12 CCC67318.1 - 1.6e-26 92.1 0.1 9e-26 89.7 0.0 2.4 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.12 CCC67318.1 - 4.3e-26 90.3 1.5 6.8e-26 89.7 0.7 1.8 2 0 0 2 2 1 1 EF hand associated Ras PF00071.22 CCC67318.1 - 8.1e-25 87.3 0.0 5.7e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CCC67318.1 - 9.9e-15 54.8 0.0 1.2e-07 31.9 0.0 2.8 2 1 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CCC67318.1 - 8.6e-09 35.5 0.0 0.00056 20.0 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.32 CCC67318.1 - 1.8e-07 30.2 7.9 4.4e-05 22.7 0.4 3.5 4 0 0 4 4 3 2 EF hand EF-hand_7 PF13499.6 CCC67318.1 - 4.6e-07 30.2 1.1 0.058 13.8 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCC67318.1 - 7e-07 28.7 0.9 0.00061 19.5 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain Dynamin_N PF00350.23 CCC67318.1 - 3.5e-05 23.9 0.0 0.018 15.1 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.6 CCC67318.1 - 4.9e-05 23.8 0.0 0.28 11.6 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain EF-hand_8 PF13833.6 CCC67318.1 - 0.00019 21.2 1.1 0.075 12.9 0.1 3.2 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 CCC67318.1 - 0.00023 20.5 3.2 0.00043 19.6 0.8 2.6 2 0 0 2 2 2 1 EF hand Arf PF00025.21 CCC67318.1 - 0.00048 19.6 0.0 0.0014 18.1 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCC67318.1 - 0.0018 17.9 0.0 3.2 7.2 0.0 3.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CCC67318.1 - 0.003 17.2 0.2 3.6 7.4 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CCC67318.1 - 0.0035 17.6 0.0 1 9.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCC67318.1 - 0.0045 16.9 0.5 0.46 10.4 0.1 3.4 3 1 0 3 3 3 1 RsgA GTPase TniB PF05621.11 CCC67318.1 - 0.005 16.3 0.1 0.043 13.2 0.0 2.1 2 0 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 CCC67318.1 - 0.0054 17.3 0.0 0.5 10.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.18 CCC67318.1 - 0.0076 15.8 0.1 1.5 8.3 0.0 3.3 3 0 0 3 3 3 1 Ferrous iron transport protein B ABC_tran PF00005.27 CCC67318.1 - 0.015 15.8 0.2 3.6 8.1 0.3 2.4 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.6 CCC67318.1 - 0.018 14.8 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCC67318.1 - 0.036 14.5 0.0 7.1 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Septin PF00735.18 CCC67318.1 - 0.037 13.3 0.0 2.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_15 PF13175.6 CCC67318.1 - 0.054 13.2 0.1 2.4 7.8 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain EF-hand_10 PF14788.6 CCC67318.1 - 0.15 12.0 0.7 2.7 7.9 0.1 2.7 2 0 0 2 2 2 0 EF hand AAA_32 PF13654.6 CCC67318.1 - 0.19 10.5 0.0 1.1 8.0 0.0 2.0 2 1 1 3 3 3 0 AAA domain Zn_clus PF00172.18 CCC67319.1 - 1.4e-10 41.1 10.7 2.7e-10 40.2 10.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRP PF06011.12 CCC67320.1 - 1.8e-154 514.6 39.0 2.2e-154 514.3 39.0 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CCC67320.1 - 3.9e-42 143.9 3.4 6.7e-42 143.1 3.4 1.4 1 0 0 1 1 1 1 ML-like domain AMP-binding PF00501.28 CCC67321.1 - 8.8e-88 294.7 0.0 1.3e-87 294.1 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCC67321.1 - 1.8e-22 80.1 2.5 2.8e-22 79.5 0.2 2.5 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CCC67321.1 - 4.4e-17 61.7 0.9 1e-16 60.6 0.9 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Kelch_5 PF13854.6 CCC67322.1 - 5.7e-11 42.2 7.1 0.041 13.9 0.1 5.9 5 1 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 CCC67322.1 - 7.9e-09 35.4 5.5 8.9e-05 22.4 0.1 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CCC67322.1 - 3.9e-08 33.3 7.1 0.12 12.7 0.1 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 CCC67322.1 - 0.0002 20.8 5.0 0.41 10.3 0.3 4.3 4 0 0 4 4 4 2 Kelch motif Alb1 PF09135.11 CCC67323.1 - 1.1e-24 87.3 14.3 3.3e-24 85.8 14.3 1.7 1 1 0 1 1 1 1 Alb1 ADH_N PF08240.12 CCC67324.1 - 4.6e-30 103.7 4.4 8.1e-30 102.9 4.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCC67324.1 - 4.4e-21 75.2 0.0 8.3e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CCC67324.1 - 1.8e-14 53.8 0.0 2.8e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus NAD_binding_7 PF13241.6 CCC67324.1 - 0.022 15.2 0.0 0.043 14.3 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 CCC67324.1 - 0.023 13.9 0.1 0.086 12.1 0.1 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCC67324.1 - 0.024 15.2 0.4 2.3 8.8 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CCC67324.1 - 0.061 13.4 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase AdoHcyase_NAD PF00670.21 CCC67324.1 - 0.97 9.5 3.8 0.51 10.4 0.1 2.2 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_N PF08240.12 CCC67325.1 - 2.1e-33 114.5 2.5 4e-33 113.6 2.5 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCC67325.1 - 8.1e-21 74.4 0.0 1.3e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 CCC67325.1 - 1.2e-08 34.7 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 CCC67325.1 - 0.0036 16.6 0.8 0.0055 16.0 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 CCC67325.1 - 0.014 14.7 0.2 0.025 13.8 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.6 CCC67325.1 - 0.03 15.4 0.0 0.057 14.5 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase DAO PF01266.24 CCC67325.1 - 0.032 13.8 0.3 0.057 13.0 0.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 CCC67325.1 - 0.048 14.2 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CCC67325.1 - 0.083 13.0 0.2 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 CCC67325.1 - 0.089 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.21 CCC67326.1 - 1.7e-77 260.4 7.9 2.2e-77 260.1 7.9 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 CCC67326.1 - 2.4e-47 160.1 0.0 5.3e-47 159.0 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain BTB PF00651.31 CCC67327.1 - 4.5e-28 97.7 0.1 2.3e-18 66.4 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.6 CCC67327.1 - 3e-08 34.0 0.1 1.3e-07 32.1 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCC67327.1 - 4.1e-06 27.3 0.1 2.5e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCC67327.1 - 0.00027 21.2 0.4 0.021 15.3 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 CCC67327.1 - 0.00039 20.7 0.0 0.015 15.7 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeat DUF3342 PF11822.8 CCC67327.1 - 0.00042 20.5 0.2 0.005 17.0 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3342) Ank_5 PF13857.6 CCC67327.1 - 0.00095 19.4 0.0 0.0034 17.7 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) RRM_1 PF00076.22 CCC67328.1 - 2.8e-07 30.3 0.1 7.4e-07 28.9 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC67328.1 - 0.023 14.8 0.0 0.038 14.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif Nop16 PF09420.10 CCC67329.1 - 4.6e-70 235.9 15.8 5.3e-70 235.7 15.8 1.0 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF2095 PF09868.9 CCC67329.1 - 0.037 14.0 3.6 0.063 13.3 3.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) Spc24 PF08286.11 CCC67329.1 - 0.045 14.0 7.1 0.12 12.6 2.1 2.8 1 1 2 3 3 3 0 Spc24 subunit of Ndc80 ORF6C PF10552.9 CCC67329.1 - 1.5 8.9 9.7 0.19 11.8 4.7 2.0 3 0 0 3 3 3 0 ORF6C domain PMI_typeI PF01238.21 CCC67330.1 - 8.2e-158 525.5 0.0 9.4e-158 525.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.19 CCC67330.1 - 7.3e-06 25.9 0.0 0.006 16.5 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_2 PF07883.11 CCC67330.1 - 0.045 13.5 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Cupin domain UPF1_Zn_bind PF09416.10 CCC67331.1 - 2.7e-66 222.2 8.6 2.7e-66 222.2 8.6 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 CCC67331.1 - 1.1e-58 198.2 0.0 2.5e-58 197.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CCC67331.1 - 7.2e-50 170.2 5.4 1.5e-26 93.7 0.9 2.3 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 CCC67331.1 - 2.6e-27 94.9 0.0 6.1e-27 93.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_30 PF13604.6 CCC67331.1 - 2e-17 63.5 0.3 5.3e-16 58.9 0.3 2.2 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCC67331.1 - 3.3e-13 50.2 0.2 7.1e-13 49.1 0.2 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CCC67331.1 - 3.3e-06 27.0 0.0 0.15 11.8 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 CCC67331.1 - 5.5e-06 25.9 0.0 0.00023 20.5 0.0 3.0 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 CCC67331.1 - 2.5e-05 24.4 0.0 5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 CCC67331.1 - 3.7e-05 23.4 0.6 0.025 14.1 0.0 2.9 2 1 0 3 3 3 2 UvrD/REP helicase N-terminal domain PIF1 PF05970.14 CCC67331.1 - 0.0024 17.1 0.0 1.2 8.2 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase Helicase_RecD PF05127.14 CCC67331.1 - 0.003 17.5 0.0 0.0066 16.3 0.0 1.6 1 0 0 1 1 1 1 Helicase PhoH PF02562.16 CCC67331.1 - 0.013 14.9 0.0 0.03 13.8 0.0 1.6 2 0 0 2 2 2 0 PhoH-like protein DEAD PF00270.29 CCC67331.1 - 0.017 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase T2SSE PF00437.20 CCC67331.1 - 0.043 12.9 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4088 PF13317.6 CCC67331.1 - 0.06 12.9 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4088) AAA_22 PF13401.6 CCC67331.1 - 0.066 13.5 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.7 CCC67331.1 - 0.082 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_24 PF13479.6 CCC67331.1 - 0.095 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2946 PF11162.8 CCC67331.1 - 0.18 12.5 2.9 0.35 11.5 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) MBR1 PF17058.5 CCC67332.1 - 1.8e-42 146.0 5.2 1.8e-42 146.0 5.2 2.3 2 0 0 2 2 2 1 Mitochondrial biogenesis regulation protein 1 TraV PF09676.10 CCC67332.1 - 0.9 10.5 6.6 0.24 12.4 1.8 2.2 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) PIR PF00399.19 CCC67333.1 - 9.3e-07 28.2 6.9 3e-06 26.6 6.9 2.0 1 0 0 1 1 1 1 Yeast PIR protein repeat DUF5570 PF17731.1 CCC67333.1 - 0.034 14.2 6.0 0.058 13.5 6.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5570) 3D PF06725.11 CCC67333.1 - 2.1 8.6 5.0 2.3 8.5 0.1 2.9 2 1 1 3 3 3 0 3D domain Peptidase_A22B PF04258.13 CCC67335.1 - 3.8e-70 236.6 15.2 6e-70 236.0 15.2 1.2 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 CCC67335.1 - 5e-05 22.9 10.8 5e-05 22.9 10.8 2.6 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease ADH_N PF08240.12 CCC67336.1 - 4.6e-30 103.7 0.7 8e-30 102.9 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCC67336.1 - 3.7e-25 88.4 0.1 5.6e-25 87.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCC67336.1 - 2.3e-05 25.5 0.0 4e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase BKACE PF05853.12 CCC67336.1 - 0.047 13.0 0.0 0.068 12.5 0.0 1.2 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Epimerase PF01370.21 CCC67336.1 - 0.06 12.8 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Copper-fist PF00649.18 CCC67336.1 - 0.091 12.3 1.6 0.18 11.3 1.6 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain YAcAr PF10686.9 CCC67336.1 - 0.16 12.0 0.1 0.28 11.2 0.1 1.4 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family DUF4772 PF15997.5 CCC67337.1 - 0.056 14.0 0.1 0.49 11.0 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4772) DUF1068 PF06364.12 CCC67337.1 - 0.77 9.6 4.6 1.9 8.3 4.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Macro_2 PF14519.6 CCC67338.1 - 4.7e-134 446.1 0.0 5.3e-134 445.9 0.0 1.0 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.21 CCC67338.1 - 0.046 13.8 0.0 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Macro domain MFS_1 PF07690.16 CCC67339.1 - 1.5e-39 135.9 35.4 1.5e-39 135.9 35.4 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC67339.1 - 1.3e-15 57.2 6.3 1.3e-15 57.2 6.3 3.3 2 1 0 2 2 2 1 Sugar (and other) transporter Pho86 PF11124.8 CCC67339.1 - 4.6 6.6 8.2 0.23 10.9 2.2 1.8 2 0 0 2 2 2 0 Inorganic phosphate transporter Pho86 Peptidase_M41 PF01434.18 CCC67340.1 - 2.3e-66 223.3 0.4 8.4e-66 221.5 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 CCC67340.1 - 3.9e-42 143.8 0.0 9.5e-42 142.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC67340.1 - 2.2e-13 49.8 0.1 6.2e-13 48.3 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain FtsH_ext PF06480.15 CCC67340.1 - 6.1e-11 42.6 1.2 1.4e-10 41.5 1.2 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 CCC67340.1 - 0.0014 18.7 0.1 0.0055 16.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 CCC67340.1 - 0.0017 18.8 1.4 0.0082 16.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 CCC67340.1 - 0.0019 17.9 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCC67340.1 - 0.0026 18.2 2.0 0.027 14.8 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 CCC67340.1 - 0.0028 17.8 0.1 0.011 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CCC67340.1 - 0.003 16.8 0.0 0.008 15.4 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain CAMSAP_CC1 PF17095.5 CCC67340.1 - 0.014 15.2 0.1 0.038 13.8 0.1 1.7 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin IstB_IS21 PF01695.17 CCC67340.1 - 0.032 14.0 0.0 0.073 12.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_22 PF13401.6 CCC67340.1 - 0.036 14.3 1.4 0.66 10.3 0.1 2.9 3 0 0 3 3 2 0 AAA domain Caskin-Pro-rich PF16907.5 CCC67340.1 - 0.069 13.7 1.0 0.18 12.3 1.0 1.7 1 0 0 1 1 1 0 Proline rich region of Caskin proteins DUF4726 PF15855.5 CCC67340.1 - 0.085 13.1 0.7 0.22 11.8 0.3 1.8 2 0 0 2 2 1 0 Domain of unknown function (DUF4726) AAA_28 PF13521.6 CCC67340.1 - 0.11 12.7 1.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CCC67340.1 - 0.18 12.0 2.8 0.22 11.7 0.0 2.7 4 1 0 4 4 3 0 AAA domain NAD_binding_10 PF13460.6 CCC67341.1 - 9.7e-49 165.8 0.0 1.1e-48 165.5 0.0 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CCC67341.1 - 3.5e-08 33.3 0.0 1.4e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.19 CCC67341.1 - 2e-06 27.0 0.1 2.9e-06 26.5 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 CCC67341.1 - 5.4e-06 26.0 0.2 3.1e-05 23.6 0.2 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 CCC67341.1 - 1.9e-05 24.9 0.1 3.3e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Semialdhyde_dh PF01118.24 CCC67341.1 - 6.5e-05 23.4 0.1 0.00011 22.6 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 CCC67341.1 - 0.00017 21.7 0.1 0.00027 21.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.20 CCC67341.1 - 0.00022 21.4 0.0 0.00037 20.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 CCC67341.1 - 0.054 14.3 0.0 0.094 13.5 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CRC_subunit PF08624.10 CCC67342.1 - 1.3e-48 164.9 0.1 2.2e-48 164.1 0.1 1.4 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit WD40 PF00400.32 CCC67343.1 - 1.9e-14 53.8 25.0 0.11 13.4 0.1 11.4 13 0 0 13 13 13 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC67343.1 - 4e-10 39.9 5.2 0.53 10.6 0.0 7.8 3 3 4 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCC67343.1 - 4.2e-05 23.5 0.5 0.22 11.4 0.0 3.9 3 2 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 CCC67343.1 - 0.0002 20.8 0.1 0.0075 15.6 0.0 2.5 2 1 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus WD40_like PF17005.5 CCC67343.1 - 0.0038 16.6 2.1 0.055 12.8 2.1 2.4 1 1 0 1 1 1 1 WD40-like domain UTP15_C PF09384.10 CCC67344.1 - 1.5e-45 154.5 1.0 2.6e-45 153.7 1.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 CCC67344.1 - 9.6e-17 61.1 9.9 0.0041 17.9 0.1 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC67344.1 - 6.8e-06 26.3 0.0 0.21 11.9 0.0 4.8 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CCC67344.1 - 0.019 15.0 0.1 13 5.8 0.0 3.9 3 3 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF5122 PF17164.4 CCC67344.1 - 0.069 13.5 0.2 0.35 11.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5122) beta-propeller Polysacc_syn_2C PF08485.10 CCC67345.1 - 0.054 13.2 0.1 0.17 11.6 0.1 1.9 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein C-terminal MMR_HSR1 PF01926.23 CCC67346.1 - 4.3e-12 46.1 0.0 1.4e-11 44.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCC67346.1 - 7.7e-07 29.2 0.5 0.003 17.5 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase NTPase_1 PF03266.15 CCC67346.1 - 0.003 17.5 0.2 0.006 16.5 0.2 1.5 1 0 0 1 1 1 1 NTPase AAA_18 PF13238.6 CCC67346.1 - 0.0034 17.9 0.1 0.01 16.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CCC67346.1 - 0.0035 17.0 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 CCC67346.1 - 0.0044 17.4 0.0 0.0079 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.23 CCC67346.1 - 0.0052 16.9 0.1 1.7 8.7 0.0 2.4 1 1 1 2 2 2 2 Dynamin family FeoB_N PF02421.18 CCC67346.1 - 0.0086 15.6 0.1 0.021 14.3 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CCC67346.1 - 0.061 12.9 0.1 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 CCC67346.1 - 0.096 12.4 0.1 0.79 9.5 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 CCC67346.1 - 0.15 11.8 0.0 0.51 10.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain mRNA_stabil PF13929.6 CCC67347.1 - 1.6e-72 243.9 10.8 2.2e-72 243.5 10.8 1.2 1 0 0 1 1 1 1 mRNA stabilisation RsfS PF02410.15 CCC67347.1 - 3.9e-13 49.7 0.1 1.1e-12 48.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal silencing factor during starvation zf-C2H2 PF00096.26 CCC67348.1 - 0.0013 19.1 3.4 0.0013 19.1 3.4 4.1 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC67348.1 - 0.0033 17.8 1.2 0.0033 17.8 1.2 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CCC67348.1 - 0.0057 17.3 5.8 0.011 16.3 0.1 3.1 2 1 1 3 3 3 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 CCC67348.1 - 0.01 16.6 15.4 0.017 15.9 1.8 4.1 3 1 0 3 3 3 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 CCC67348.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.7 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Secretin_N_2 PF07655.13 CCC67348.1 - 0.13 12.8 10.5 0.27 11.8 4.5 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain C1_1 PF00130.22 CCC67348.1 - 0.19 11.7 3.5 0.53 10.2 0.4 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PriA_CRR PF18319.1 CCC67348.1 - 2.1 8.4 6.5 0.96 9.5 0.3 3.0 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain zf-C2HE PF16278.5 CCC67348.1 - 2.6 8.5 8.0 16 6.0 0.0 3.6 3 1 0 4 4 4 0 C2HE / C2H2 / C2HC zinc-binding finger zf-Di19 PF05605.12 CCC67348.1 - 2.8 8.3 6.2 1.5 9.2 2.8 2.4 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding MRP-L28 PF09812.9 CCC67349.1 - 3.3e-25 89.1 1.1 4.1e-25 88.8 1.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Bul1_C PF04426.12 CCC67349.1 - 0.0067 15.9 0.5 0.0086 15.5 0.5 1.2 1 0 0 1 1 1 1 Bul1 C terminus Raptor_N PF14538.6 CCC67349.1 - 0.061 13.3 0.3 0.083 12.8 0.3 1.3 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain FYRC PF05965.14 CCC67349.1 - 0.088 13.0 0.5 0.21 11.8 0.2 1.9 1 1 0 2 2 2 0 F/Y rich C-terminus DUF413 PF04219.12 CCC67349.1 - 0.12 12.4 0.4 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF Csm1_N PF18504.1 CCC67349.1 - 0.42 11.0 2.8 0.54 10.6 0.4 2.0 2 0 0 2 2 2 0 Csm1 N-terminal domain MAT1 PF06391.13 CCC67351.1 - 4.4e-71 238.9 28.4 5.3e-71 238.7 28.4 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4_5 PF17121.5 CCC67351.1 - 4.9e-27 93.6 8.0 9.9e-27 92.6 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCC67351.1 - 0.00096 19.4 6.0 0.0017 18.6 6.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCC67351.1 - 0.002 17.9 3.6 0.0046 16.8 3.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CCC67351.1 - 0.0048 16.7 6.8 0.017 14.9 7.0 1.8 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCC67351.1 - 0.0049 16.7 5.5 0.03 14.2 5.8 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC67351.1 - 0.046 13.8 6.5 0.093 12.8 6.5 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 CCC67351.1 - 0.17 11.9 8.5 2.7 8.0 9.0 2.2 1 1 1 2 2 2 0 zinc-RING finger domain FliS PF02561.14 CCC67351.1 - 0.17 12.2 10.1 0.25 11.6 2.9 2.2 1 1 1 2 2 2 0 Flagellar protein FliS Prok-RING_4 PF14447.6 CCC67351.1 - 3.2 7.7 9.6 13 5.7 0.4 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 CCC67351.1 - 5.1 7.0 10.1 36 4.2 10.2 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain TRAPP PF04051.16 CCC67352.1 - 4.1e-45 153.1 0.0 5.1e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Phage_Treg PF04761.12 CCC67352.1 - 0.084 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator Ribosomal_L27e PF01777.18 CCC67353.1 - 3.4e-36 123.5 7.8 5.6e-36 122.8 7.8 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CCC67353.1 - 0.00051 19.9 1.2 0.0011 18.9 1.2 1.6 1 0 0 1 1 1 1 KOW motif Ndr PF03096.14 CCC67353.1 - 0.049 12.3 0.0 0.093 11.4 0.0 1.4 1 0 0 1 1 1 0 Ndr family Mito_carr PF00153.27 CCC67354.1 - 1.2e-12 47.6 0.0 7.3e-05 22.6 0.0 3.7 3 1 0 3 3 3 2 Mitochondrial carrier protein DUF4118 PF13493.6 CCC67354.1 - 0.16 11.7 1.6 0.34 10.7 1.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) DUF5418 PF17439.2 CCC67354.1 - 0.35 11.0 10.4 0.19 11.8 4.1 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF5418) Dpy-30 PF05186.13 CCC67355.1 - 5.5e-15 54.8 0.0 7.3e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Use1 PF09753.9 CCC67356.1 - 7.9e-06 25.8 3.4 1e-05 25.4 3.4 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 CCC67356.1 - 8.9e-06 25.6 0.4 8.9e-06 25.6 0.4 2.3 4 0 0 4 4 1 1 SNARE domain Sulfatase_C PF14707.6 CCC67356.1 - 0.0037 18.0 1.0 0.82 10.4 0.1 2.6 2 1 1 3 3 3 1 C-terminal region of aryl-sulfatase ALMT PF11744.8 CCC67356.1 - 0.023 13.6 5.3 0.04 12.7 5.1 1.5 1 1 0 1 1 1 0 Aluminium activated malate transporter Sororin PF09666.10 CCC67356.1 - 0.038 14.2 0.9 0.056 13.7 0.8 1.4 1 1 0 1 1 1 0 Sororin protein Endotoxin_N PF03945.14 CCC67356.1 - 0.042 13.5 1.5 0.071 12.8 1.5 1.4 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Spc7 PF08317.11 CCC67356.1 - 0.044 12.7 12.0 0.054 12.4 2.7 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Sec20 PF03908.13 CCC67356.1 - 0.048 13.6 6.1 0.071 13.0 0.1 2.4 2 1 0 2 2 2 0 Sec20 DUF2408 PF10303.9 CCC67356.1 - 0.049 14.2 9.2 0.31 11.6 7.9 2.6 2 1 1 3 3 2 0 Protein of unknown function (DUF2408) Syntaxin-6_N PF09177.11 CCC67356.1 - 0.051 14.1 11.9 0.52 10.9 7.4 3.2 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Vps53_N PF04100.12 CCC67356.1 - 0.072 12.0 10.0 0.012 14.6 5.5 1.7 2 0 0 2 2 2 0 Vps53-like, N-terminal CCD PF07860.11 CCC67356.1 - 0.078 13.0 0.7 0.15 12.1 0.1 1.7 2 0 0 2 2 1 0 WisP family C-Terminal Region DUF3584 PF12128.8 CCC67356.1 - 0.083 10.4 10.5 0.12 9.9 10.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF2207 PF09972.9 CCC67356.1 - 0.12 11.1 0.7 0.34 9.6 0.7 1.8 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Noelin-1 PF12308.8 CCC67356.1 - 0.13 12.3 10.0 1.9 8.5 0.6 2.5 2 1 0 2 2 2 0 Neurogenesis glycoprotein OmpH PF03938.14 CCC67356.1 - 0.14 12.5 8.7 0.37 11.1 8.2 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1054 PF06335.12 CCC67356.1 - 0.15 12.0 1.6 0.27 11.1 1.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1054) Occludin_ELL PF07303.13 CCC67356.1 - 0.15 12.8 10.1 2.3 9.0 3.0 2.9 2 1 0 2 2 2 0 Occludin homology domain FlaC_arch PF05377.11 CCC67356.1 - 0.16 12.4 12.5 6 7.3 0.2 3.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) SKA1 PF07160.12 CCC67356.1 - 0.17 11.7 9.2 1.1 9.1 0.5 2.4 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 ETRAMP PF09716.10 CCC67356.1 - 0.19 11.8 0.6 3.9 7.6 0.3 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4200 PF13863.6 CCC67356.1 - 0.19 12.1 14.8 0.03 14.7 6.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) BST2 PF16716.5 CCC67356.1 - 0.22 12.2 13.7 0.085 13.5 5.6 2.7 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 DUF4208 PF13907.6 CCC67356.1 - 0.23 11.9 6.8 0.64 10.5 1.9 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) DUF3209 PF11483.8 CCC67356.1 - 0.24 11.8 6.4 0.12 12.8 1.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) Apolipoprotein PF01442.18 CCC67356.1 - 0.25 11.2 12.6 0.12 12.2 1.5 2.8 1 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Phage_GPO PF05929.11 CCC67356.1 - 0.26 10.9 6.7 0.07 12.7 1.5 1.9 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RmuC PF02646.16 CCC67356.1 - 0.28 10.3 10.0 0.26 10.4 0.5 2.7 2 1 0 2 2 2 0 RmuC family DUF5617 PF18493.1 CCC67356.1 - 0.32 11.1 2.9 0.42 10.8 0.9 2.2 2 1 0 2 2 1 0 Domain of unknown function (DUF5617) MCPsignal PF00015.21 CCC67356.1 - 0.34 10.7 5.9 0.3 10.9 3.0 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain MCU PF04678.13 CCC67356.1 - 0.42 10.7 7.9 4.8 7.2 0.1 2.1 1 1 1 2 2 2 0 Mitochondrial calcium uniporter WXG100 PF06013.12 CCC67356.1 - 0.65 10.3 8.7 11 6.4 0.3 3.7 2 2 1 3 3 2 0 Proteins of 100 residues with WXG Sec34 PF04136.15 CCC67356.1 - 0.69 9.8 10.8 0.45 10.4 3.9 2.8 2 2 1 3 3 3 0 Sec34-like family AHSP PF09236.10 CCC67356.1 - 0.72 10.3 0.1 0.72 10.3 0.1 2.9 3 1 0 3 3 2 0 Alpha-haemoglobin stabilising protein YtxH PF12732.7 CCC67356.1 - 0.78 10.3 7.6 12 6.6 3.7 3.1 2 1 0 2 2 2 0 YtxH-like protein Baculo_PEP_C PF04513.12 CCC67356.1 - 0.8 9.7 12.9 3.2 7.8 0.8 3.0 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1043 PF06295.12 CCC67356.1 - 0.96 9.5 9.7 0.14 12.2 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1043) Cdh1_DBD_1 PF18196.1 CCC67356.1 - 1.2 9.5 7.5 1.1 9.5 2.5 2.2 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DUF948 PF06103.11 CCC67356.1 - 1.2 9.4 13.7 40 4.6 0.6 3.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF1845 PF08900.11 CCC67356.1 - 1.4 8.6 4.8 1.1 9.0 0.4 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF1845) Flagellin_N PF00669.20 CCC67356.1 - 1.5 9.0 6.5 9.5 6.3 1.3 2.4 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF745 PF05335.13 CCC67356.1 - 1.6 8.4 10.1 1.2 8.8 1.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF2203 PF09969.9 CCC67356.1 - 1.8 9.3 7.4 0.98 10.2 2.1 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Cnn_1N PF07989.11 CCC67356.1 - 1.8 8.8 13.2 0.88 9.8 0.6 3.2 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF1664 PF07889.12 CCC67356.1 - 2.5 8.2 15.0 4.8 7.2 1.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) RIG-I_C PF18119.1 CCC67356.1 - 2.5 8.1 9.3 1.5 8.9 0.4 2.5 2 1 0 2 2 2 0 RIG-I receptor C-terminal domain Ibs_toxin PF13956.6 CCC67356.1 - 3.7 7.7 11.1 5.8 7.0 11.1 1.3 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system DUF16 PF01519.16 CCC67356.1 - 4 8.0 18.5 1.1 9.8 3.1 2.5 1 1 1 2 2 2 0 Protein of unknown function DUF16 Med9 PF07544.13 CCC67356.1 - 5.9 7.1 11.1 0.71 10.0 1.4 2.9 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Fez1 PF06818.15 CCC67356.1 - 6.4 7.2 13.2 1.2e+02 3.1 12.8 2.1 1 1 0 1 1 1 0 Fez1 CCDC-167 PF15188.6 CCC67356.1 - 8 6.9 12.7 1.1 9.7 0.5 3.3 2 2 1 3 3 3 0 Coiled-coil domain-containing protein 167 Atg14 PF10186.9 CCC67356.1 - 8.9 5.3 8.1 7.1 5.6 3.6 2.0 1 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Pkinase PF00069.25 CCC67357.1 - 2.9e-66 223.6 0.1 4.5e-66 222.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67357.1 - 4.2e-34 118.0 0.0 6.7e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC67357.1 - 6.4e-10 38.8 0.0 1.8e-09 37.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CCC67357.1 - 0.0072 16.3 0.0 0.025 14.5 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CCC67357.1 - 0.011 15.0 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CCC67357.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 CCC67357.1 - 0.08 12.6 1.1 5.6 6.5 0.0 2.4 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Cellulase PF00150.18 CCC67358.1 - 6.3e-12 45.5 9.0 1.3e-11 44.5 9.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Apc13p PF05839.11 CCC67359.1 - 1.3e-07 31.7 0.9 1.9e-07 31.1 0.9 1.2 1 0 0 1 1 1 1 Apc13p protein bZIP_1 PF00170.21 CCC67360.1 - 6.9e-09 35.7 9.4 1.2e-08 35.0 9.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.18 CCC67360.1 - 0.1 12.8 0.6 0.17 12.1 0.6 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper Presenilin PF01080.17 CCC67360.1 - 0.3 9.8 3.2 0.45 9.2 3.2 1.2 1 0 0 1 1 1 0 Presenilin SH3BGR PF04908.15 CCC67360.1 - 0.31 11.2 1.7 1.3 9.2 0.2 2.4 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein NYD-SP28_assoc PF14775.6 CCC67360.1 - 0.57 10.3 2.9 1.2 9.2 2.9 1.6 1 0 0 1 1 1 0 Sperm tail C-terminal domain bZIP_2 PF07716.15 CCC67360.1 - 6.7 6.9 10.8 15 5.8 10.8 1.6 1 1 0 1 1 1 0 Basic region leucine zipper bZIP_1 PF00170.21 CCC67361.1 - 6.7e-10 38.9 10.2 1.4e-09 37.9 10.2 1.6 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.18 CCC67361.1 - 0.0012 19.0 1.9 0.002 18.3 1.9 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper CENP-B_dimeris PF09026.10 CCC67361.1 - 0.0055 17.1 6.4 0.0055 17.1 6.4 2.4 2 0 0 2 2 2 1 Centromere protein B dimerisation domain JMY PF15871.5 CCC67361.1 - 0.0067 15.8 1.3 0.0094 15.3 1.3 1.3 1 0 0 1 1 1 1 Junction-mediating and -regulatory protein ORC6 PF05460.13 CCC67361.1 - 0.0071 15.7 5.1 0.011 15.1 5.1 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) bZIP_Maf PF03131.17 CCC67361.1 - 0.022 15.2 6.9 0.071 13.6 6.9 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor DUF4611 PF15387.6 CCC67361.1 - 0.31 11.3 12.0 0.28 11.4 4.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Shadoo PF14999.6 CCC67361.1 - 3 7.9 7.6 1.4 9.0 5.4 1.6 1 1 1 2 2 2 0 Shadow of prion protein, neuroprotective DUF3246 PF11596.8 CCC67361.1 - 7.9 5.8 12.3 15 4.9 12.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) AAA_2 PF07724.14 CCC67362.1 - 4.5e-51 173.3 0.1 2e-48 164.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 CCC67362.1 - 2.3e-36 123.9 7.2 2.5e-36 123.8 1.0 2.6 2 0 0 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 CCC67362.1 - 7.5e-26 90.0 0.2 2.6e-25 88.3 0.2 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 CCC67362.1 - 1.8e-21 77.0 0.1 5.3e-11 43.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CCC67362.1 - 2.3e-15 56.8 0.2 1.2e-10 41.5 0.0 3.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCC67362.1 - 5e-12 46.5 2.8 0.00048 20.5 0.1 4.4 2 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 CCC67362.1 - 5.6e-08 33.2 0.1 0.034 14.4 0.0 3.5 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CCC67362.1 - 3.4e-07 30.1 0.1 2.6e-05 24.0 0.0 2.7 2 1 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 CCC67362.1 - 4.6e-07 29.4 0.1 0.0004 19.9 0.0 4.0 3 1 0 3 3 3 1 Bacterial TniB protein ATPase_2 PF01637.18 CCC67362.1 - 1.5e-06 28.3 5.7 0.12 12.3 0.1 4.2 4 1 1 5 5 4 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CCC67362.1 - 1.6e-06 28.1 0.0 0.027 14.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 CCC67362.1 - 5.9e-06 26.1 0.0 0.04 13.7 0.0 3.0 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_7 PF12775.7 CCC67362.1 - 6.1e-06 25.9 0.0 0.017 14.6 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region ABC_tran PF00005.27 CCC67362.1 - 6.2e-05 23.5 0.5 0.12 12.9 0.0 3.1 3 0 0 3 3 3 1 ABC transporter RsgA_GTPase PF03193.16 CCC67362.1 - 7.9e-05 22.6 0.0 0.044 13.7 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 CCC67362.1 - 0.00017 21.6 0.0 0.16 11.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 CCC67362.1 - 0.00026 21.6 0.0 0.44 11.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CCC67362.1 - 0.00037 20.5 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CCC67362.1 - 0.00037 20.8 0.0 0.45 10.7 0.0 3.2 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 CCC67362.1 - 0.00038 19.8 0.0 0.016 14.5 0.0 3.1 2 1 1 3 3 3 1 Zeta toxin AAA_30 PF13604.6 CCC67362.1 - 0.00042 20.1 0.0 1.3 8.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CCC67362.1 - 0.00062 19.5 0.0 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain Roc PF08477.13 CCC67362.1 - 0.00094 19.4 0.0 1.6 8.9 0.0 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CCC67362.1 - 0.001 18.8 0.0 0.42 10.3 0.0 2.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 CCC67362.1 - 0.0011 19.3 0.0 1.8 9.0 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_21 PF13304.6 CCC67362.1 - 0.0021 17.9 3.0 0.84 9.4 0.0 3.9 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF815 PF05673.13 CCC67362.1 - 0.0026 17.0 1.2 0.63 9.2 0.4 3.2 3 2 0 3 3 3 1 Protein of unknown function (DUF815) AAA_6 PF12774.7 CCC67362.1 - 0.0062 15.5 0.1 0.14 11.1 0.0 2.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region SRP54 PF00448.22 CCC67362.1 - 0.012 15.2 0.0 1.9 8.1 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 CCC67362.1 - 0.014 15.1 0.0 5.3 6.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CCC67362.1 - 0.014 14.7 0.0 1.7 8.0 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CCC67362.1 - 0.015 15.7 2.3 10 6.4 0.3 3.9 2 2 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 CCC67362.1 - 0.027 14.3 0.0 3 7.6 0.0 2.7 2 0 0 2 2 2 0 Bacterial dnaA protein MMR_HSR1 PF01926.23 CCC67362.1 - 0.028 14.5 0.0 2.6 8.2 0.0 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase T2SSE PF00437.20 CCC67362.1 - 0.029 13.4 0.1 0.12 11.4 0.1 2.1 2 1 0 2 2 2 0 Type II/IV secretion system protein Torsin PF06309.11 CCC67362.1 - 0.029 14.5 0.0 0.065 13.3 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_3 PF07726.11 CCC67362.1 - 0.037 13.9 0.1 0.75 9.7 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CCC67362.1 - 0.037 13.6 0.1 2.1 7.9 0.0 3.0 4 0 0 4 4 3 0 AAA domain AAA_33 PF13671.6 CCC67362.1 - 0.04 14.1 0.2 6.6 6.9 0.0 2.9 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.17 CCC67362.1 - 0.061 13.4 1.3 1.6 8.7 0.0 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain ResIII PF04851.15 CCC67362.1 - 0.065 13.2 0.0 2.7 8.0 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit PhoH PF02562.16 CCC67362.1 - 0.086 12.3 0.0 3.6 7.0 0.0 2.6 2 0 0 2 2 2 0 PhoH-like protein ATP_bind_1 PF03029.17 CCC67362.1 - 0.1 12.3 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_23 PF13476.6 CCC67362.1 - 0.21 12.1 18.7 9.8 6.6 0.1 3.6 2 2 0 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.9 CCC67362.1 - 1 9.4 15.5 0.41 10.7 6.2 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SET PF00856.28 CCC67363.1 - 8.9e-22 78.3 0.0 1.6e-21 77.5 0.0 1.4 1 0 0 1 1 1 1 SET domain FlaG PF03646.15 CCC67363.1 - 0.076 13.2 0.3 11 6.3 0.0 2.8 2 0 0 2 2 2 0 FlaG protein Pex24p PF06398.11 CCC67364.1 - 1.3e-80 271.1 9.0 2.1e-80 270.5 9.0 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rpr2 PF04032.16 CCC67365.1 - 7.9e-12 45.3 0.0 7.9e-12 45.3 0.0 2.2 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain TFIIS_C PF01096.18 CCC67365.1 - 0.75 9.7 4.6 12 5.9 0.5 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Pkinase PF00069.25 CCC67366.1 - 2e-77 260.1 0.2 3e-77 259.5 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain AdenylateSensor PF16579.5 CCC67366.1 - 1.4e-56 190.0 0.1 3.2e-56 188.9 0.1 1.6 1 0 0 1 1 1 1 Adenylate sensor of SNF1-like protein kinase Pkinase_Tyr PF07714.17 CCC67366.1 - 1.4e-38 132.7 0.0 2e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.11 CCC67366.1 - 9.5e-20 70.4 0.9 9.5e-20 70.4 0.9 2.0 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.6 CCC67366.1 - 2.3e-10 40.3 0.0 3.4e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 CCC67366.1 - 7e-06 25.8 1.0 1.3e-05 24.9 1.0 1.4 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 CCC67366.1 - 0.00013 21.1 0.8 0.00025 20.1 0.8 1.5 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 CCC67366.1 - 0.00038 19.4 0.5 0.00056 18.8 0.5 1.2 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 CCC67366.1 - 0.006 16.0 0.2 0.01 15.2 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCC67366.1 - 0.044 13.7 0.2 0.63 9.9 0.2 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Usp PF00582.26 CCC67368.1 - 0.014 15.9 0.0 0.034 14.6 0.0 1.7 1 0 0 1 1 1 0 Universal stress protein family PRP3 PF08572.10 CCC67369.1 - 2.5e-56 190.9 17.7 4.5e-56 190.1 17.7 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 CCC67369.1 - 4.2e-33 114.5 0.5 4.2e-33 114.5 0.5 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) RNA_Me_trans PF04252.13 CCC67370.1 - 8.2e-78 260.6 0.0 9.2e-78 260.4 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DUF3020 PF11223.8 CCC67371.1 - 3.5e-19 69.1 7.2 3.5e-19 69.1 7.2 7.6 7 0 0 7 7 7 1 Protein of unknown function (DUF3020) UIM PF02809.20 CCC67371.1 - 1.3 9.1 4.2 2.5 8.2 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin interaction motif Methyltransf_4 PF02390.17 CCC67372.1 - 0.048 13.1 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.12 CCC67372.1 - 0.11 13.2 0.0 0.2 12.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ArgJ PF01960.18 CCC67373.1 - 3.1e-141 470.5 9.0 3.6e-141 470.3 9.0 1.0 1 0 0 1 1 1 1 ArgJ family Suf PF05843.14 CCC67374.1 - 5.1e-63 213.8 22.3 8.6e-56 190.1 6.3 3.7 3 1 1 4 4 4 3 Suppressor of forked protein (Suf) DUF3150 PF11348.8 CCC67374.1 - 0.01 15.1 0.2 0.022 14.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) DUF842 PF05811.13 CCC67374.1 - 0.02 14.6 2.5 0.055 13.2 2.5 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Tom37_C PF11801.8 CCC67375.1 - 1.3e-44 151.8 0.1 2.4e-44 150.9 0.1 1.4 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.9 CCC67375.1 - 6.1e-29 100.9 0.3 1.1e-28 100.0 0.3 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein AbiGii_2 PF16873.5 CCC67375.1 - 0.075 11.8 0.5 0.11 11.2 0.5 1.2 1 0 0 1 1 1 0 Putative abortive phage resistance protein AbiGii toxin DUF4448 PF14610.6 CCC67376.1 - 4.7e-49 166.7 0.7 6.7e-49 166.2 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3492 PF11997.8 CCC67377.1 - 0.076 12.7 0.5 1.4 8.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3492) Cu-oxidase_2 PF07731.14 CCC67378.1 - 4.5e-44 149.5 10.7 3.1e-40 137.1 1.3 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.15 CCC67378.1 - 1.8e-43 147.4 4.0 4.4e-40 136.4 0.5 3.2 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.22 CCC67378.1 - 4.6e-33 114.6 8.3 4.8e-31 108.0 2.6 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.6 CCC67378.1 - 0.04 14.0 0.0 0.47 10.6 0.0 2.8 4 0 0 4 4 4 0 Cupredoxin-like domain Mito_carr PF00153.27 CCC67379.1 - 2.2e-68 226.2 4.5 1.7e-23 82.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RabGAP-TBC PF00566.18 CCC67380.1 - 2.1e-32 112.5 0.2 4.4e-32 111.5 0.2 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain V_ATPase_I PF01496.19 CCC67381.1 - 0 1018.8 4.0 0 1018.6 4.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family FliD_C PF07195.12 CCC67381.1 - 0.0055 16.1 1.6 0.39 10.1 0.1 2.6 2 0 0 2 2 2 2 Flagellar hook-associated protein 2 C-terminus Baculo_PEP_C PF04513.12 CCC67381.1 - 0.0079 16.2 7.5 0.82 9.7 1.9 2.7 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus YabA PF06156.13 CCC67381.1 - 0.016 15.9 0.2 0.85 10.3 0.0 2.7 2 0 0 2 2 2 0 Initiation control protein YabA BLOC1_2 PF10046.9 CCC67381.1 - 0.11 12.8 2.8 9.4 6.6 0.1 2.9 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CLZ PF16526.5 CCC67381.1 - 0.16 12.3 1.3 1.8 9.0 0.0 2.6 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4988 PF16378.5 CCC67381.1 - 0.45 10.2 4.3 6.6 6.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF948 PF06103.11 CCC67381.1 - 0.48 10.7 5.4 3.9 7.8 1.4 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) COG2 PF06148.11 CCC67381.1 - 0.92 9.6 4.2 1.3 9.1 0.6 2.5 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Fib_alpha PF08702.10 CCC67381.1 - 4.3 7.5 8.1 8.4 6.6 0.9 3.1 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF3450 PF11932.8 CCC67382.1 - 0.00082 18.7 0.6 0.0019 17.6 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) KASH_CCD PF14662.6 CCC67382.1 - 0.019 14.8 6.8 0.051 13.4 6.8 1.7 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Josephin PF02099.17 CCC67382.1 - 0.031 14.4 4.5 4.2 7.5 2.8 3.3 2 1 0 2 2 2 0 Josephin Cob_adeno_trans PF01923.18 CCC67382.1 - 0.096 12.8 0.8 0.23 11.6 0.8 1.7 1 0 0 1 1 1 0 Cobalamin adenosyltransferase LEA_4 PF02987.16 CCC67382.1 - 0.19 11.8 0.7 0.39 10.8 0.7 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein FMN_dh PF01070.18 CCC67382.1 - 0.32 10.0 1.3 0.45 9.5 0.2 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase DUF1664 PF07889.12 CCC67382.1 - 3.4 7.7 8.0 1.2 9.1 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Vps55 PF04133.14 CCC67383.1 - 1.5e-41 141.0 8.6 1.7e-41 140.8 8.6 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF998 PF06197.13 CCC67383.1 - 0.065 12.8 3.4 0.15 11.6 0.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF998) HSP70 PF00012.20 CCC67384.1 - 3.1e-268 890.9 14.8 3.6e-268 890.7 14.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCC67384.1 - 2.7e-15 56.0 2.9 5.1e-13 48.5 0.7 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CCC67384.1 - 0.0017 18.1 0.0 0.0038 17.0 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF5321 PF17254.2 CCC67384.1 - 0.094 12.1 9.3 0.018 14.5 2.0 3.1 3 1 1 4 4 4 0 Family of unknown function (DUF5321) MRP-S27 PF10037.9 CCC67384.1 - 0.25 10.1 7.6 0.43 9.4 7.6 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 Syntaxin_2 PF14523.6 CCC67384.1 - 0.47 10.9 8.8 0.31 11.4 4.0 2.5 1 1 1 2 2 2 0 Syntaxin-like protein Stathmin PF00836.19 CCC67384.1 - 0.55 10.2 12.1 0.3 11.1 8.6 2.2 1 1 1 2 2 2 0 Stathmin family YlbD_coat PF14071.6 CCC67384.1 - 0.65 10.2 6.8 1.7 9.0 6.8 1.7 1 0 0 1 1 1 0 Putative coat protein Het-C PF07217.11 CCC67384.1 - 0.7 8.3 5.0 1.2 7.6 5.0 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C FtsA PF14450.6 CCC67384.1 - 1 9.9 14.6 0.46 10.9 0.6 4.3 3 2 0 3 3 3 0 Cell division protein FtsA DUF948 PF06103.11 CCC67384.1 - 1.3 9.3 3.8 2.6 8.3 1.5 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CDT1_C PF16679.5 CCC67385.1 - 6.5e-06 26.5 0.4 2.5e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 DNA replication factor Cdt1 C-terminal domain CDT1 PF08839.11 CCC67385.1 - 0.0014 18.9 1.7 0.026 14.8 2.6 2.5 2 1 0 2 2 2 1 DNA replication factor CDT1 like zf-RING_2 PF13639.6 CCC67386.1 - 2.5e-10 40.5 12.1 2.5e-10 40.5 12.1 1.6 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CCC67386.1 - 2.5e-09 37.3 10.6 2.1e-08 34.3 10.1 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCC67386.1 - 1.2e-05 25.2 6.1 2.8e-05 24.1 6.1 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CCC67386.1 - 1.4e-05 24.9 11.4 1.4e-05 24.9 11.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC67386.1 - 9.8e-05 22.3 9.9 0.00021 21.2 9.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CCC67386.1 - 0.00015 21.5 13.1 0.00036 20.3 10.8 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCC67386.1 - 0.0026 17.5 7.7 0.0026 17.5 7.7 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 CCC67386.1 - 0.015 15.3 9.6 0.017 15.1 8.3 1.8 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.8 CCC67386.1 - 0.02 15.1 8.1 0.02 15.1 8.1 2.9 2 2 0 2 2 2 0 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 CCC67386.1 - 0.025 14.5 11.7 0.053 13.4 10.2 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCC67386.1 - 0.06 13.2 13.3 0.27 11.1 6.3 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Nucleoporin_FG PF13634.6 CCC67387.1 - 3.7e-51 171.9 323.2 3.8e-11 43.7 40.7 9.9 3 2 8 11 11 11 10 Nucleoporin FG repeat region Nucleoporin2 PF04096.14 CCC67387.1 - 1.1e-32 113.3 0.0 2.6e-32 112.0 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin autopeptidase Swi3 PF07962.12 CCC67388.1 - 3.4e-29 100.6 0.5 6e-29 99.9 0.5 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 CDC27 PF09507.10 CCC67389.1 - 0.00025 20.6 30.4 0.00041 19.9 30.4 1.3 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Blt1 PF12754.7 CCC67389.1 - 1.1 9.6 6.1 0.31 11.4 0.2 2.8 3 0 0 3 3 3 0 Blt1 N-terminal domain TEX19 PF15553.6 CCC67389.1 - 3.5 7.6 11.0 0.083 12.9 3.0 2.3 3 0 0 3 3 3 0 Testis-expressed protein 19 ATP-synt_C PF00137.21 CCC67390.1 - 4.9e-34 116.5 31.3 2.4e-22 79.0 12.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF2970 PF11174.8 CCC67390.1 - 2.2 8.2 9.9 0.87 9.5 1.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Urb2 PF10441.9 CCC67391.1 - 1.8e-56 191.3 2.8 1.8e-56 191.3 2.8 2.7 3 0 0 3 3 3 1 Urb2/Npa2 family EFG_C PF00679.24 CCC67391.1 - 0.044 13.8 0.0 0.19 11.8 0.0 2.1 1 0 0 1 1 1 0 Elongation factor G C-terminus Voltage_CLC PF00654.20 CCC67392.1 - 5.5e-79 266.0 22.5 5.5e-79 266.0 22.5 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 CCC67392.1 - 6.8e-16 58.5 0.0 3.4e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain UL45 PF05473.12 CCC67392.1 - 0.21 11.2 0.1 0.21 11.2 0.1 1.8 2 0 0 2 2 2 0 UL45 protein, carbohydrate-binding C-type lectin-like DUF1656 PF07869.12 CCC67392.1 - 3 7.9 8.1 1.1 9.3 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1656) Ribosomal_L7Ae PF01248.26 CCC67393.1 - 1e-27 95.7 0.1 1.2e-27 95.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 CCC67393.1 - 0.0018 18.1 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 CCC67393.1 - 0.012 15.6 0.0 0.013 15.5 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 Pico_P2B PF01552.17 CCC67393.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 1 1 2 2 2 0 Picornavirus 2B protein HECT PF00632.25 CCC67395.1 - 1.3e-82 277.8 2.3 2.5e-82 276.8 2.3 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.22 CCC67395.1 - 0.016 15.1 2.1 0.063 13.2 2.1 2.1 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SNF2_N PF00176.23 CCC67396.1 - 7.1e-72 242.0 0.1 1.2e-71 241.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCC67396.1 - 6.6e-20 71.5 0.0 2.7e-19 69.6 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC67396.1 - 5.5e-07 29.7 0.0 5.5e-07 29.7 0.0 3.7 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit PHD PF00628.29 CCC67397.1 - 2e-05 24.4 8.7 3.4e-05 23.6 8.7 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CCC67397.1 - 0.011 16.0 4.3 0.03 14.6 4.3 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain Pet191_N PF10203.9 CCC67398.1 - 2.6e-23 82.1 3.8 3.6e-23 81.6 3.8 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.13 CCC67398.1 - 0.032 14.4 1.3 0.73 10.0 0.3 2.7 2 0 0 2 2 2 0 CHCH domain CX9C PF16860.5 CCC67398.1 - 0.25 11.4 5.7 1.9 8.6 0.2 3.2 3 0 0 3 3 3 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Rav1p_C PF12234.8 CCC67399.1 - 2.3e-247 822.5 1.7 2.2e-246 819.3 0.2 2.1 2 0 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.32 CCC67399.1 - 0.018 15.9 16.4 8.6 7.4 0.1 7.4 8 0 0 8 8 8 0 WD domain, G-beta repeat HPS3_N PF14761.6 CCC67399.1 - 0.61 9.6 3.5 0.34 10.4 0.4 2.0 2 0 0 2 2 2 0 Hermansky-Pudlak syndrome 3 Pro_isomerase PF00160.21 CCC67400.1 - 2.6e-39 135.0 0.0 4.2e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CCC67400.1 - 5.9e-10 38.5 12.7 1e-05 25.3 1.4 3.8 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCC67400.1 - 2.5e-09 36.6 14.7 3.1e-07 29.9 3.5 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCC67400.1 - 0.0021 18.3 0.4 5.1 7.5 0.6 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCC67400.1 - 0.004 17.3 2.3 0.004 17.3 2.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCC67400.1 - 0.0073 16.0 3.6 1.1 9.0 0.3 2.8 2 0 0 2 2 2 2 TPR repeat TPR_6 PF13174.6 CCC67400.1 - 0.013 16.1 0.3 0.013 16.1 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCC67400.1 - 0.1 13.3 0.0 2.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec7 PF01369.20 CCC67401.1 - 8.5e-62 208.1 2.5 8.5e-62 208.1 2.5 1.8 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 CCC67401.1 - 1.8e-15 57.2 3.8 1.8e-15 57.2 3.8 3.4 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal tRNA-synt_2 PF00152.20 CCC67402.1 - 1.5e-71 241.1 0.0 2e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCC67402.1 - 5e-06 26.4 0.0 9.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PMP1_2 PF08114.11 CCC67403.1 - 9.9e-26 89.2 3.8 1e-25 89.1 3.8 1.0 1 0 0 1 1 1 1 ATPase proteolipid family FeoB_associated PF12669.7 CCC67403.1 - 0.0082 16.5 1.2 0.01 16.2 1.2 1.2 1 1 0 1 1 1 1 FeoB-associated Cys-rich membrane protein LapA_dom PF06305.11 CCC67403.1 - 0.033 14.0 1.7 0.035 13.9 1.7 1.0 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain CD34_antigen PF06365.12 CCC67403.1 - 0.063 12.9 0.3 0.063 12.9 0.3 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family OppC_N PF12911.7 CCC67403.1 - 0.066 13.2 0.1 0.07 13.1 0.1 1.1 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Spore_YpjB PF09577.10 CCC67403.1 - 0.13 12.1 0.1 0.13 12.0 0.1 1.0 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Phosphodiest PF01663.22 CCC67404.1 - 6.6e-44 150.9 1.0 1e-43 150.4 0.2 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Trypan_PARP PF05887.11 CCC67404.1 - 0.19 11.7 6.1 0.51 10.3 6.1 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SPESP1 PF15754.5 CCC67404.1 - 0.48 9.5 4.9 1.1 8.3 4.9 1.5 1 0 0 1 1 1 0 Sperm equatorial segment protein 1 Ras PF00071.22 CCC67405.1 - 2.5e-43 147.5 0.2 2.9e-43 147.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC67405.1 - 6.3e-15 55.5 0.0 9.4e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC67405.1 - 8.1e-14 51.4 0.2 9.9e-14 51.2 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCC67405.1 - 1.5e-06 28.2 0.1 3.2e-06 27.2 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCC67405.1 - 4.8e-06 26.2 2.0 0.00014 21.5 0.2 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CCC67405.1 - 0.00017 21.1 0.4 0.00021 20.8 0.4 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CCC67405.1 - 0.0016 18.4 0.2 0.017 15.0 0.1 2.2 2 1 0 2 2 2 1 RsgA GTPase DUF1904 PF08921.11 CCC67405.1 - 0.056 13.8 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1904) FeoB_N PF02421.18 CCC67405.1 - 0.057 12.9 0.1 0.1 12.1 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_14 PF13173.6 CCC67405.1 - 0.073 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain PfkB PF00294.24 CCC67406.1 - 3.7e-09 36.3 0.0 1.2e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase TENA_THI-4 PF03070.16 CCC67407.1 - 2.1e-10 40.8 1.5 2.9e-10 40.3 1.5 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family LSM PF01423.22 CCC67408.1 - 4.8e-11 42.2 0.0 6e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CCC67408.1 - 0.019 15.1 0.0 0.033 14.3 0.0 1.6 1 1 0 1 1 1 0 RimP C-terminal SH3 domain BPL_C PF02237.17 CCC67408.1 - 0.091 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Remorin_N PF03766.13 CCC67408.1 - 0.11 12.6 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Remorin, N-terminal region Frag1 PF10277.9 CCC67411.1 - 1.3e-31 109.9 14.8 1.3e-31 109.9 14.8 3.9 3 2 0 3 3 3 1 Frag1/DRAM/Sfk1 family Exo_endo_phos PF03372.23 CCC67411.1 - 0.029 13.9 0.0 0.054 13.0 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family Caps_synth_CapC PF14102.6 CCC67411.1 - 6.4 7.2 18.0 0.025 15.0 1.8 3.1 2 0 0 2 2 2 0 Capsule biosynthesis CapC Glyco_transf_15 PF01793.16 CCC67412.1 - 1.2e-94 317.2 10.8 1.5e-94 316.9 10.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DNA_pol_B_thumb PF14791.6 CCC67413.1 - 7.3e-19 67.7 0.4 1.9e-18 66.4 0.2 1.8 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.6 CCC67413.1 - 2e-17 63.4 0.0 8.8e-16 58.1 0.0 2.7 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.6 CCC67413.1 - 5.6e-13 49.1 0.8 1.2e-12 48.0 0.8 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.9 CCC67413.1 - 6.9e-06 25.8 0.1 7.5e-05 22.5 0.0 2.7 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda BRCT PF00533.26 CCC67413.1 - 9e-06 26.0 0.1 0.0022 18.3 0.1 3.4 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCC67413.1 - 0.01 16.2 0.1 0.021 15.2 0.1 1.6 1 0 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain PGK PF00162.19 CCC67414.1 - 6.1e-151 502.7 0.4 6.9e-151 502.5 0.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase ABC2_membrane PF01061.24 CCC67415.1 - 2.4e-38 131.7 19.9 4.4e-38 130.8 19.9 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 CCC67415.1 - 1.3e-26 93.7 0.0 2.3e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CCC67415.1 - 0.00071 19.5 1.1 1.2 8.9 0.2 2.6 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CCC67415.1 - 0.0059 16.5 0.2 0.012 15.6 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CCC67415.1 - 0.022 14.5 1.4 0.034 13.9 0.3 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain EGF_2 PF07974.13 CCC67415.1 - 0.055 13.9 25.0 0.02 15.3 6.3 3.8 3 0 0 3 3 3 0 EGF-like domain AAA_28 PF13521.6 CCC67415.1 - 0.063 13.5 0.3 0.12 12.6 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CCC67415.1 - 0.21 12.1 4.3 0.72 10.3 4.1 2.0 1 1 0 1 1 1 0 AAA domain RNA_pol_Rpc34 PF05158.12 CCC67416.1 - 2.9e-107 358.9 0.6 3.5e-107 358.7 0.6 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.20 CCC67416.1 - 0.016 15.5 1.8 0.025 14.9 0.2 2.1 2 0 0 2 2 2 0 Transcriptional regulator DUF2529 PF10740.9 CCC67416.1 - 0.018 14.7 0.4 0.038 13.6 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) HTH_46 PF15977.5 CCC67416.1 - 0.16 12.0 0.9 0.49 10.4 0.2 2.2 2 0 0 2 2 2 0 Winged helix-turn-helix DNA binding DUF3944 PF13099.6 CCC67416.1 - 0.16 11.8 0.1 0.31 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3944) RPA_C PF08784.11 CCC67416.1 - 0.26 12.0 1.9 0.77 10.4 0.0 2.4 1 1 1 2 2 2 0 Replication protein A C terminal B-block_TFIIIC PF04182.12 CCC67416.1 - 0.31 11.2 3.7 2.4 8.4 0.1 2.4 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC Gpr1_Fun34_YaaH PF01184.19 CCC67417.1 - 2.2e-95 318.1 18.6 2.6e-95 317.9 18.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family BAR PF03114.18 CCC67418.1 - 4.4e-54 183.6 1.2 6e-54 183.2 1.2 1.2 1 0 0 1 1 1 1 BAR domain DUF1496 PF07383.12 CCC67418.1 - 0.009 15.6 0.7 0.019 14.6 0.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1496) MgtE_N PF03448.17 CCC67418.1 - 0.043 14.4 0.7 0.2 12.3 0.0 2.4 4 0 0 4 4 4 0 MgtE intracellular N domain Baculo_p33 PF05214.12 CCC67418.1 - 0.067 12.9 2.9 0.15 11.8 2.9 1.5 1 0 0 1 1 1 0 Baculovirus P33 DUF5339 PF17274.2 CCC67418.1 - 9.6 7.1 7.3 5.9 7.8 3.3 2.7 3 1 0 3 3 3 0 Family of unknown function (DUF5339) Pkinase PF00069.25 CCC67419.1 - 4.1e-49 167.3 0.0 7.4e-49 166.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67419.1 - 4.7e-28 98.2 0.0 7.6e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC67419.1 - 0.026 13.8 0.0 0.065 12.5 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 CCC67419.1 - 0.05 13.0 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCC67419.1 - 0.2 11.5 0.0 0.33 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family IZUMO PF15005.6 CCC67420.1 - 0.68 10.4 6.6 0.42 11.1 0.3 2.8 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Sugar_tr PF00083.24 CCC67421.1 - 1.1e-161 538.7 33.5 1.3e-161 538.5 33.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC67421.1 - 3.9e-28 98.4 38.3 2.3e-24 86.0 25.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CCC67421.1 - 0.0021 16.5 4.4 0.0041 15.6 4.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector Secretin_N_2 PF07655.13 CCC67421.1 - 0.01 16.4 4.8 0.019 15.5 4.8 1.4 1 0 0 1 1 1 1 Secretin N-terminal domain DUF1772 PF08592.11 CCC67421.1 - 0.03 14.6 8.5 3.5 7.9 0.1 4.5 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) DUF4834 PF16118.5 CCC67421.1 - 0.27 12.2 1.7 1.5 9.8 0.9 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) adh_short PF00106.25 CCC67422.1 - 7.7e-48 162.5 1.3 9.5e-48 162.2 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCC67422.1 - 5.1e-32 111.3 0.1 6e-32 111.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCC67422.1 - 3.3e-12 46.7 0.1 4.5e-12 46.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CCC67422.1 - 0.003 17.0 0.1 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCC67422.1 - 0.0041 16.2 0.1 0.0072 15.4 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CCC67422.1 - 0.045 13.6 0.0 0.067 13.1 0.0 1.4 1 1 0 1 1 1 0 NAD(P)H-binding AlaDh_PNT_N PF05222.15 CCC67423.1 - 1.7e-30 106.1 0.0 2.5e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PS_pyruv_trans PF04230.13 CCC67423.1 - 0.0061 16.5 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase AlaDh_PNT_C PF01262.21 CCC67423.1 - 0.056 12.7 0.0 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Ank_2 PF12796.7 CCC67424.1 - 1.5e-10 41.5 0.1 4e-10 40.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 CCC67424.1 - 2.7e-10 40.2 0.1 4.1e-06 27.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 CCC67424.1 - 2.9e-10 40.4 0.1 2.6e-05 24.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.24 CCC67424.1 - 4.5e-09 36.3 0.2 4e-08 33.2 0.0 2.7 2 0 0 2 2 2 1 IPT/TIG domain Ank_3 PF13606.6 CCC67424.1 - 5.6e-09 35.5 0.1 2e-05 24.6 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 CCC67424.1 - 1.1e-05 25.5 0.1 0.00061 20.0 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF1163 PF06651.11 CCC67424.1 - 0.068 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1163) RHD_dimer PF16179.5 CCC67424.1 - 0.14 12.2 0.0 0.41 10.7 0.0 1.8 1 0 0 1 1 1 0 Rel homology dimerisation domain MutS_V PF00488.21 CCC67425.1 - 2.2e-85 285.4 0.3 4.3e-85 284.5 0.3 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCC67425.1 - 9.4e-35 120.6 1.4 9.4e-35 120.6 1.4 2.8 3 1 0 3 3 3 1 MutS domain III MutS_II PF05188.17 CCC67425.1 - 3.8e-20 72.6 0.3 3.8e-20 72.6 0.3 2.8 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 CCC67425.1 - 9.6e-19 67.5 1.1 9.6e-19 67.5 1.1 2.2 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.20 CCC67425.1 - 1.3e-12 47.9 0.2 1e-11 45.0 0.0 2.4 3 0 0 3 3 3 1 MutS domain I RACo_linker PF17650.1 CCC67425.1 - 0.026 14.4 0.2 2 8.4 0.0 2.9 2 0 0 2 2 2 0 RACo linker region PhoU PF01895.19 CCC67425.1 - 0.03 14.8 6.3 0.49 10.9 0.0 4.1 4 0 0 4 4 4 0 PhoU domain RsbRD_N PF14361.6 CCC67425.1 - 0.061 14.0 1.7 0.12 13.1 0.3 2.3 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain DivIC PF04977.15 CCC67425.1 - 6 6.7 7.3 11 5.9 0.1 3.4 3 0 0 3 3 3 0 Septum formation initiator CCDC144C PF14915.6 CCC67426.1 - 0.0044 16.2 14.8 0.0044 16.2 14.8 3.1 2 1 1 3 3 3 2 CCDC144C protein coiled-coil region ATG16 PF08614.11 CCC67426.1 - 0.0097 16.2 11.4 0.0097 16.2 11.4 3.8 2 1 2 4 4 4 1 Autophagy protein 16 (ATG16) Phage_GP20 PF06810.11 CCC67426.1 - 0.027 14.3 25.4 0.027 14.3 10.1 3.6 1 1 2 3 3 3 0 Phage minor structural protein GP20 Spc7 PF08317.11 CCC67426.1 - 0.11 11.4 35.4 0.014 14.3 23.1 2.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Exonuc_VII_L PF02601.15 CCC67426.1 - 3 7.3 27.0 0.58 9.7 12.1 2.4 1 1 1 2 2 2 0 Exonuclease VII, large subunit Seryl_tRNA_N PF02403.22 CCC67426.1 - 4.9 7.4 32.6 0.034 14.4 7.7 3.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Jnk-SapK_ap_N PF09744.9 CCC67426.1 - 7.2 6.8 35.8 0.53 10.5 21.2 2.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.9 CCC67426.1 - 9.3 5.6 35.4 1.8 7.9 25.2 2.4 1 1 1 2 2 2 0 Golgin subfamily A member 5 PQ-loop PF04193.14 CCC67427.1 - 2.6e-18 65.5 3.5 2.6e-18 65.5 3.5 2.1 3 0 0 3 3 3 1 PQ loop repeat Steroid_dh PF02544.16 CCC67427.1 - 0.065 13.2 0.6 0.14 12.1 0.6 1.7 1 1 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase tRNA_m1G_MT PF01746.21 CCC67428.1 - 3e-40 138.0 0.1 5.3e-40 137.2 0.1 1.4 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Rep_fac_C PF08542.11 CCC67429.1 - 3.2e-21 75.5 0.1 1.3e-20 73.5 0.0 2.1 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CCC67429.1 - 3.5e-13 49.7 0.1 2.2e-10 40.6 0.1 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA PF00004.29 CCC67429.1 - 4.1e-13 49.9 0.0 7.8e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CCC67429.1 - 7.4e-07 29.3 0.0 1.3e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCC67429.1 - 2.1e-06 28.2 0.0 0.00074 19.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCC67429.1 - 6.7e-06 26.4 0.2 0.1 12.8 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.11 CCC67429.1 - 8.8e-05 22.4 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 CCC67429.1 - 0.0002 21.2 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RuvB_N PF05496.12 CCC67429.1 - 0.00079 19.2 0.0 0.0023 17.7 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 CCC67429.1 - 0.00096 19.0 0.5 0.0015 18.4 0.5 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CCC67429.1 - 0.00097 19.1 0.0 0.0027 17.7 0.0 1.8 1 1 0 1 1 1 1 Rad17 P-loop domain TniB PF05621.11 CCC67429.1 - 0.0017 17.8 0.1 0.65 9.4 0.0 2.3 2 0 0 2 2 2 2 Bacterial TniB protein AAA_assoc_2 PF16193.5 CCC67429.1 - 0.0028 18.0 0.0 0.015 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA C-terminal domain Mg_chelatase PF01078.21 CCC67429.1 - 0.0094 15.4 0.0 0.12 11.7 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 CCC67429.1 - 0.024 14.4 0.0 0.052 13.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 CCC67429.1 - 0.033 14.0 0.0 0.06 13.1 0.1 1.3 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 CCC67429.1 - 0.05 12.6 0.0 0.33 9.9 0.0 2.1 1 1 1 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_19 PF13245.6 CCC67429.1 - 0.064 13.6 0.2 0.44 10.9 0.2 2.3 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 CCC67429.1 - 0.071 13.0 0.1 0.52 10.2 0.0 2.2 1 1 1 2 2 2 0 NTPase DUF2075 PF09848.9 CCC67429.1 - 0.13 11.5 0.1 5.9 6.0 0.1 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) Iso_dh PF00180.20 CCC67430.1 - 3.3e-75 253.4 0.1 3.8e-75 253.2 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_76 PF03663.14 CCC67431.1 - 1.8e-149 498.3 16.2 1.8e-149 498.3 16.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CCC67431.1 - 0.00034 19.8 5.3 0.0032 16.6 0.7 2.4 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.14 CCC67432.1 - 2.1e-147 491.4 9.1 2.5e-147 491.2 9.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.13 CCC67432.1 - 0.0035 16.5 6.2 0.68 8.9 2.2 2.4 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 EF-hand_6 PF13405.6 CCC67433.1 - 0.00016 21.3 1.0 0.2 11.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 CCC67433.1 - 0.0002 21.7 0.8 0.0002 21.7 0.8 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 CCC67433.1 - 0.00096 19.0 0.6 0.0022 17.8 0.6 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 CCC67433.1 - 0.025 14.1 2.3 0.031 13.8 0.8 2.1 2 0 0 2 2 2 0 EF hand ABC_tran PF00005.27 CCC67434.1 - 3.8e-44 150.5 0.1 6.4e-22 78.6 0.0 4.5 3 2 0 3 3 2 2 ABC transporter 4HB PF17947.1 CCC67434.1 - 5.7e-27 93.6 0.1 3.5e-26 91.0 0.1 2.5 1 0 0 1 1 1 1 Four helical bundle domain AAA_21 PF13304.6 CCC67434.1 - 2.2e-17 63.9 0.2 0.0093 15.8 0.0 5.2 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCC67434.1 - 2.5e-15 56.5 0.0 5.6e-07 29.2 0.0 3.8 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCC67434.1 - 2.9e-09 37.7 6.3 0.00079 20.0 0.0 3.7 4 0 0 4 4 3 2 AAA domain RsgA_GTPase PF03193.16 CCC67434.1 - 1.4e-08 34.8 0.1 0.00014 21.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CCC67434.1 - 1.8e-08 34.0 0.0 0.0043 16.8 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMS19_C PF12460.8 CCC67434.1 - 8.9e-08 31.7 3.3 0.002 17.3 0.2 3.3 2 1 1 3 3 3 2 RNAPII transcription regulator C-terminal AAA_22 PF13401.6 CCC67434.1 - 1.3e-07 32.0 0.3 0.03 14.6 0.0 4.4 5 1 0 5 5 3 2 AAA domain MMR_HSR1 PF01926.23 CCC67434.1 - 1.4e-07 31.5 0.0 0.0021 18.1 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase Dynamin_N PF00350.23 CCC67434.1 - 3e-07 30.6 0.0 3.3e-05 24.0 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.6 CCC67434.1 - 7.1e-07 29.6 0.1 0.0089 16.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 CCC67434.1 - 3.9e-06 27.3 1.1 1.3 9.4 0.0 4.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CCC67434.1 - 1.2e-05 25.6 0.0 0.13 12.7 0.0 3.0 3 0 0 3 3 2 2 RNA helicase HEAT_EZ PF13513.6 CCC67434.1 - 1.9e-05 25.1 2.8 0.29 11.7 0.2 4.6 4 1 1 5 5 4 1 HEAT-like repeat AAA_18 PF13238.6 CCC67434.1 - 1.9e-05 25.2 0.0 0.31 11.6 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CCC67434.1 - 4.8e-05 23.8 0.1 0.25 11.7 0.0 3.6 4 0 0 4 4 3 1 AAA ATPase domain AAA_33 PF13671.6 CCC67434.1 - 5.5e-05 23.3 0.0 0.4 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_27 PF13514.6 CCC67434.1 - 9.7e-05 22.1 0.0 0.12 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CCC67434.1 - 0.00013 21.1 0.1 0.37 9.7 0.1 2.5 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB ParcG PF10274.9 CCC67434.1 - 0.00089 19.4 0.7 0.38 10.8 0.2 3.1 2 1 1 3 3 3 1 Parkin co-regulated protein AAA_15 PF13175.6 CCC67434.1 - 0.0016 18.2 5.9 0.2 11.3 0.0 3.7 5 0 0 5 5 4 2 AAA ATPase domain DUF87 PF01935.17 CCC67434.1 - 0.0018 18.4 6.9 0.38 10.8 0.1 4.5 5 0 0 5 5 4 1 Helicase HerA, central domain AAA_24 PF13479.6 CCC67434.1 - 0.0023 17.7 0.0 1.5 8.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.6 CCC67434.1 - 0.0025 18.0 0.0 0.81 10.0 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UME PF08064.13 CCC67434.1 - 0.0027 17.6 3.1 0.032 14.1 0.8 2.7 1 1 1 2 2 2 1 UME (NUC010) domain AAA_30 PF13604.6 CCC67434.1 - 0.0041 16.8 1.8 2.7 7.7 0.1 3.6 4 0 0 4 4 3 1 AAA domain NACHT PF05729.12 CCC67434.1 - 0.0044 16.9 0.0 1.6 8.6 0.0 2.7 2 0 0 2 2 2 1 NACHT domain HEAT_2 PF13646.6 CCC67434.1 - 0.0045 17.4 4.4 0.035 14.5 0.9 3.1 2 1 2 4 4 3 3 HEAT repeats PduV-EutP PF10662.9 CCC67434.1 - 0.0052 16.5 0.0 0.25 11.1 0.0 3.1 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.15 CCC67434.1 - 0.0056 16.6 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain ATPase_2 PF01637.18 CCC67434.1 - 0.0059 16.5 0.1 7.7 6.3 0.0 3.4 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CCC67434.1 - 0.011 15.8 0.0 9.2 6.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 CCC67434.1 - 0.012 15.3 0.0 6.1 6.4 0.0 3.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CLP1_P PF16575.5 CCC67434.1 - 0.013 15.3 0.0 1.4 8.6 0.0 2.9 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Cytidylate_kin PF02224.18 CCC67434.1 - 0.014 15.1 0.0 6.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase ATP_bind_1 PF03029.17 CCC67434.1 - 0.023 14.5 0.6 8 6.2 0.1 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MutS_V PF00488.21 CCC67434.1 - 0.024 14.7 0.1 5.3 7.0 0.1 2.6 2 0 0 2 2 2 0 MutS domain V T2SSE PF00437.20 CCC67434.1 - 0.024 13.7 0.0 0.41 9.7 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 CCC67434.1 - 0.026 14.7 0.0 12 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 CCC67434.1 - 0.034 13.4 0.0 2.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Septin Tricho_coat PF05892.11 CCC67434.1 - 0.037 13.8 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 1 0 Trichovirus coat protein NTPase_1 PF03266.15 CCC67434.1 - 0.057 13.3 0.0 14 5.5 0.1 2.7 2 0 0 2 2 2 0 NTPase CLASP_N PF12348.8 CCC67434.1 - 0.059 12.9 1.7 12 5.4 0.1 2.9 1 1 1 2 2 2 0 CLASP N terminal AAA_7 PF12775.7 CCC67434.1 - 0.068 12.7 0.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 CCC67434.1 - 0.069 13.1 0.0 16 5.3 0.0 2.6 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 IstB_IS21 PF01695.17 CCC67434.1 - 0.076 12.7 0.0 16 5.2 0.0 3.0 2 0 0 2 2 2 0 IstB-like ATP binding protein Adaptin_N PF01602.20 CCC67434.1 - 0.081 11.5 6.8 0.12 10.8 4.1 2.0 1 1 0 1 1 1 0 Adaptin N terminal region GTP_EFTU PF00009.27 CCC67434.1 - 0.083 12.4 0.0 13 5.3 0.0 2.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Mg_chelatase PF01078.21 CCC67434.1 - 0.098 12.0 0.3 1.5 8.2 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 CCC67434.1 - 0.39 11.2 3.2 30 5.0 0.8 3.7 2 1 0 2 2 2 0 AAA domain MukB PF04310.12 CCC67434.1 - 0.54 10.0 2.0 35 4.1 0.1 3.0 3 0 0 3 3 3 0 MukB N-terminal AAA_13 PF13166.6 CCC67434.1 - 1.2 7.7 14.3 2 6.9 0.0 4.4 5 0 0 5 5 5 0 AAA domain Pkinase PF00069.25 CCC67435.1 - 7.1e-58 196.0 0.0 3.8e-56 190.4 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67435.1 - 1.7e-23 83.2 0.0 2.4e-21 76.2 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC67435.1 - 7.2e-06 25.5 0.1 0.042 13.2 0.1 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CCC67435.1 - 0.00069 19.0 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CCC67435.1 - 0.054 13.1 1.2 0.1 12.2 0.0 2.1 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCC67435.1 - 0.17 11.8 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family SNF2_N PF00176.23 CCC67436.1 - 5.7e-45 153.6 0.2 2e-44 151.8 0.0 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain zf-RING_2 PF13639.6 CCC67436.1 - 2.4e-10 40.6 9.4 7.3e-10 39.0 9.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCC67436.1 - 4.6e-09 36.0 10.0 1.1e-08 34.8 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CCC67436.1 - 5.7e-09 35.7 7.5 1.2e-08 34.6 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCC67436.1 - 7.3e-09 35.4 10.0 2e-08 34.0 10.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CCC67436.1 - 6.1e-07 29.6 5.9 1.9e-06 28.0 5.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CCC67436.1 - 1.7e-06 28.0 6.4 4.5e-06 26.6 6.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 CCC67436.1 - 3.9e-06 26.7 9.1 1.1e-05 25.3 9.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCC67436.1 - 0.00013 21.8 6.5 0.00027 20.7 6.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 NEMO PF11577.8 CCC67436.1 - 0.0003 20.8 0.1 0.0018 18.2 0.1 2.4 1 0 0 1 1 1 1 NF-kappa-B essential modulator NEMO zf-C3HC4_4 PF15227.6 CCC67436.1 - 0.00079 19.5 8.6 0.002 18.3 8.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Helicase_C PF00271.31 CCC67436.1 - 0.0034 17.7 0.1 0.0034 17.7 0.1 3.4 4 0 0 4 4 3 1 Helicase conserved C-terminal domain zf-RING_10 PF16685.5 CCC67436.1 - 0.0059 16.7 4.5 0.023 14.8 4.5 2.0 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 CCC67436.1 - 0.014 15.5 3.2 0.029 14.4 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-P11 PF03854.14 CCC67436.1 - 0.05 13.3 8.2 0.15 11.8 8.2 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-Nse PF11789.8 CCC67436.1 - 0.16 11.8 4.6 0.53 10.1 4.6 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 CCC67436.1 - 0.62 9.9 8.1 0.58 9.9 6.0 2.2 2 0 0 2 2 1 0 RING-like zinc finger zf-RING_4 PF14570.6 CCC67436.1 - 4.3 7.2 7.2 12 5.8 7.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Clat_adaptor_s PF01217.20 CCC67437.1 - 1.1e-54 184.2 0.2 1.3e-54 184.0 0.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.20 CCC67438.1 - 4.4e-27 95.4 0.0 6.3e-27 94.9 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.6 CCC67438.1 - 0.072 13.1 0.1 0.27 11.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) DUF3357 PF11837.8 CCC67439.1 - 0.24 11.9 0.1 0.42 11.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) ABC1 PF03109.16 CCC67440.1 - 4e-31 107.6 0.0 7.9e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CCC67440.1 - 0.0008 19.1 0.0 0.0038 16.8 0.0 2.0 2 0 0 2 2 2 1 RIO1 family Zn_clus PF00172.18 CCC67442.1 - 5.5e-08 32.8 8.4 1e-07 31.9 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CCC67442.1 - 0.00058 19.0 12.2 0.0028 16.7 12.2 2.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain TPR_MLP1_2 PF07926.12 CCC67444.1 - 0.00049 20.2 14.6 0.00049 20.2 14.6 1.8 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 CCC67444.1 - 0.00088 19.8 11.4 0.0011 19.5 11.4 1.1 1 0 0 1 1 1 1 Fez1 Spc7 PF08317.11 CCC67444.1 - 0.0011 18.0 13.3 0.0016 17.4 13.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein NRIP1_repr_1 PF15687.5 CCC67444.1 - 0.0021 17.8 3.0 0.0027 17.4 3.0 1.2 1 0 0 1 1 1 1 Nuclear receptor-interacting protein 1 repression 1 bZIP_1 PF00170.21 CCC67444.1 - 0.0032 17.5 2.8 0.0032 17.5 2.8 3.3 3 1 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 CCC67444.1 - 0.0068 16.5 3.2 0.0068 16.5 3.2 3.6 2 1 2 4 4 4 1 Basic region leucine zipper FAM76 PF16046.5 CCC67444.1 - 0.019 14.3 9.9 0.02 14.3 9.1 1.4 1 1 0 1 1 1 0 FAM76 protein DUF4795 PF16043.5 CCC67444.1 - 0.033 13.8 10.8 0.051 13.2 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TMPIT PF07851.13 CCC67444.1 - 0.054 12.7 8.3 0.063 12.5 8.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein SlyX PF04102.12 CCC67444.1 - 0.061 14.0 14.2 2.8 8.6 1.5 3.3 1 1 2 3 3 3 0 SlyX V_ATPase_I PF01496.19 CCC67444.1 - 0.064 11.2 9.3 0.065 11.2 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BLOC1_2 PF10046.9 CCC67444.1 - 0.076 13.3 14.9 0.095 13.0 7.0 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 CCC67444.1 - 0.095 12.0 20.1 0.62 9.4 4.4 2.1 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding TIR-like PF10137.9 CCC67444.1 - 0.17 11.8 2.1 0.29 11.1 2.1 1.4 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain Exonuc_VII_L PF02601.15 CCC67444.1 - 0.23 11.0 7.4 0.25 10.9 7.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF724 PF05266.14 CCC67444.1 - 0.3 10.9 13.5 0.43 10.4 11.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ADIP PF11559.8 CCC67444.1 - 0.33 11.0 16.0 0.1 12.7 11.8 1.9 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Jnk-SapK_ap_N PF09744.9 CCC67444.1 - 0.37 11.0 17.9 0.53 10.5 17.9 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 CCC67444.1 - 0.42 9.1 1.3 0.49 8.9 1.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family YabA PF06156.13 CCC67444.1 - 0.43 11.3 19.0 0.43 11.2 5.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA Pox_A_type_inc PF04508.12 CCC67444.1 - 0.88 9.5 4.4 23 5.1 0.2 3.2 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat Laminin_II PF06009.12 CCC67444.1 - 1.2 9.2 11.9 2.2 8.3 11.9 1.5 1 0 0 1 1 1 0 Laminin Domain II MPS2 PF17060.5 CCC67444.1 - 1.5 8.0 10.9 3.3 6.9 10.9 1.7 1 1 0 1 1 1 0 Monopolar spindle protein 2 Occludin_ELL PF07303.13 CCC67444.1 - 1.7 9.4 9.7 0.48 11.2 5.0 2.2 1 1 1 2 2 2 0 Occludin homology domain Fzo_mitofusin PF04799.13 CCC67444.1 - 1.7 8.1 9.8 5.3 6.6 9.8 1.9 1 1 0 1 1 1 0 fzo-like conserved region DUF3450 PF11932.8 CCC67444.1 - 1.9 7.7 15.8 0.19 11.0 3.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) HIP1_clath_bdg PF16515.5 CCC67444.1 - 2.7 8.7 18.3 4 8.1 14.3 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-C4H2 PF10146.9 CCC67444.1 - 3.3 8.0 12.7 5 7.4 12.7 1.4 1 1 0 1 1 1 0 Zinc finger-containing protein ZapB PF06005.12 CCC67444.1 - 3.5 8.1 27.1 0.8 10.2 8.5 2.4 1 1 1 2 2 2 0 Cell division protein ZapB ACCA PF03255.14 CCC67444.1 - 6.1 6.7 12.7 0.83 9.5 6.1 2.2 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Glycogen_syn PF05693.13 CCC67445.1 - 0 1129.3 0.0 0 1129.1 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 CCC67445.1 - 1.1e-08 34.8 0.0 2.6e-06 27.1 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCC67445.1 - 1.2e-06 29.0 0.0 0.002 18.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCC67445.1 - 0.00018 21.6 0.3 0.00041 20.4 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 CCC67445.1 - 0.00039 20.9 0.0 0.00082 19.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.11 CCC67445.1 - 0.0028 17.4 0.1 0.006 16.3 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Pkinase PF00069.25 CCC67446.1 - 9.6e-71 238.2 0.0 1.4e-70 237.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67446.1 - 1.9e-40 138.8 0.0 2.8e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC67446.1 - 0.0018 17.1 0.1 0.0037 16.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CCC67446.1 - 0.0057 16.0 0.0 0.034 13.5 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CCC67446.1 - 0.14 11.5 0.1 0.21 10.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WHIM1 PF15612.6 CCC67447.1 - 2.1e-07 30.3 0.0 5.5e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 SNARE PF05739.19 CCC67448.1 - 5.4e-15 55.1 0.5 1.2e-14 54.1 0.5 1.6 1 0 0 1 1 1 1 SNARE domain MYO10_CC PF16735.5 CCC67448.1 - 0.012 15.6 2.3 0.033 14.3 2.3 1.8 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain GET2 PF08690.10 CCC67448.1 - 0.02 14.6 4.9 0.021 14.5 3.8 1.6 1 1 0 1 1 1 0 GET complex subunit GET2 VEGFR-2_TMD PF17988.1 CCC67448.1 - 0.51 9.8 2.3 1.2 8.6 2.3 1.6 1 0 0 1 1 1 0 VEGFR-2 Transmembrane domain SUR7 PF06687.12 CCC67449.1 - 1.2e-17 64.2 20.1 2e-17 63.6 20.1 1.3 1 0 0 1 1 1 1 SUR7/PalI family ODV-E18 PF10717.9 CCC67449.1 - 0.28 11.1 0.1 0.28 11.1 0.1 3.5 3 1 2 5 5 5 0 Occlusion-derived virus envelope protein ODV-E18 AA_permease PF00324.21 CCC67450.1 - 4.6e-125 417.9 41.2 5.2e-125 417.7 41.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC67450.1 - 4.5e-34 118.0 42.0 6.2e-34 117.5 42.0 1.2 1 0 0 1 1 1 1 Amino acid permease PDCD2_C PF04194.13 CCC67451.1 - 5.7e-43 147.0 0.0 7.7e-40 136.8 0.0 2.4 2 0 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain NPF PF16601.5 CCC67451.1 - 0.013 16.0 3.1 0.027 14.9 3.1 1.5 1 0 0 1 1 1 0 Rabosyn-5 repeating NPF sequence-motif GTP_EFTU PF00009.27 CCC67452.1 - 1.3e-28 99.8 9.3 1.1e-27 96.8 5.5 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CCC67452.1 - 2.2e-23 82.4 0.2 6.1e-23 81.0 0.2 1.8 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 CCC67452.1 - 5.7e-10 38.9 0.0 1.6e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 CCC67452.1 - 6.1e-09 36.0 0.4 2.4e-08 34.0 0.4 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCC67452.1 - 0.00067 19.2 0.5 0.0026 17.3 0.5 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B FeoB_Cyto PF17910.1 CCC67452.1 - 0.0018 18.8 1.4 0.0056 17.2 0.9 2.1 2 0 0 2 2 2 1 FeoB cytosolic helical domain RsgA_GTPase PF03193.16 CCC67452.1 - 0.0022 17.9 3.5 0.028 14.3 0.7 2.9 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 CCC67452.1 - 0.0092 15.4 0.1 0.026 14.0 0.1 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CCC67452.1 - 0.013 15.1 0.1 0.042 13.4 0.0 1.9 1 1 0 1 1 1 0 Ras family GTP_EFTU_D2 PF03144.25 CCC67452.1 - 0.051 14.0 8.4 0.25 11.7 0.2 3.5 4 1 0 4 4 3 0 Elongation factor Tu domain 2 Dynamin_N PF00350.23 CCC67452.1 - 0.083 12.9 2.8 8.1 6.5 0.2 3.4 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.9 CCC67452.1 - 0.13 12.0 1.4 0.72 9.6 0.8 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TIP120 PF08623.10 CCC67453.1 - 2e-05 24.4 1.9 0.00028 20.7 0.1 2.6 2 0 0 2 2 2 2 TATA-binding protein interacting (TIP20) ANAPC4_WD40 PF12894.7 CCC67454.1 - 2.9e-09 37.1 0.0 0.0017 18.6 0.0 3.9 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCC67454.1 - 2.7e-08 34.3 0.0 0.032 15.1 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CCC67454.1 - 2.2e-05 23.6 0.5 0.023 13.7 0.1 2.5 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_N PF14781.6 CCC67454.1 - 0.17 11.8 1.6 30 4.6 0.1 3.5 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal Arrestin_C PF02752.22 CCC67455.1 - 1.4e-22 80.6 0.5 8.3e-22 78.1 0.0 2.5 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCC67455.1 - 4.1e-09 36.6 0.2 8.5e-08 32.4 0.0 2.8 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CCC67455.1 - 6.3e-06 26.0 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like RRM_1 PF00076.22 CCC67456.1 - 9.5e-44 147.1 9.0 6e-15 54.8 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCC67456.1 - 6.9e-07 28.9 2.3 0.098 12.3 0.1 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC67456.1 - 0.00018 21.5 0.1 1.1 9.4 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CCC67456.1 - 0.00023 21.1 0.2 6.5 6.8 0.0 3.6 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CCC67456.1 - 0.0017 18.3 1.2 1.8 8.7 0.0 4.4 5 0 0 5 5 5 1 RNA binding motif Nup35_RRM PF05172.13 CCC67456.1 - 0.0028 17.6 0.3 0.16 12.0 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 CCC67456.1 - 0.0045 16.8 0.0 2.7 7.9 0.0 3.5 4 0 0 4 4 4 1 Occluded RNA-recognition motif Ysc84 PF04366.12 CCC67457.1 - 3.2e-42 143.3 0.4 5.6e-42 142.5 0.4 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CCC67457.1 - 1.6e-15 56.4 0.1 1.6e-15 56.4 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CCC67457.1 - 3.9e-13 49.0 0.0 8.9e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCC67457.1 - 3.7e-12 45.7 0.0 8.1e-12 44.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF1776 PF08643.10 CCC67458.1 - 7.2e-37 127.3 0.3 1e-36 126.8 0.3 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Lyase_1 PF00206.20 CCC67459.1 - 6.7e-97 324.6 0.0 9.3e-97 324.2 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.6 CCC67459.1 - 6e-22 78.2 0.0 1.4e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal tRNA-synt_2 PF00152.20 CCC67460.1 - 4.2e-91 305.3 0.0 6.3e-91 304.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCC67460.1 - 3.5e-13 49.3 0.3 6.5e-13 48.5 0.3 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.11 CCC67460.1 - 0.015 14.8 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain ProRS-C_1 PF09180.11 CCC67461.1 - 1.3e-25 89.4 2.5 1.3e-25 89.4 2.5 2.4 3 0 0 3 3 3 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 CCC67461.1 - 2.2e-20 72.6 0.1 5.7e-20 71.3 0.1 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CCC67461.1 - 1.1e-15 58.0 0.0 2.1e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 CCC67461.1 - 0.039 14.0 0.1 0.067 13.3 0.1 1.3 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain DSPn PF14671.6 CCC67462.1 - 1.3e-46 158.5 0.0 5.8e-46 156.4 0.0 1.9 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CCC67462.1 - 4e-23 81.7 0.0 9.3e-22 77.3 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 CCC67462.1 - 0.00022 20.9 0.1 0.00043 20.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 CCC67462.1 - 0.00041 20.0 0.0 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CCC67462.1 - 0.0014 18.8 0.0 0.0045 17.1 0.0 1.8 2 0 0 2 2 2 1 Inositol hexakisphosphate BPL_LplA_LipB PF03099.19 CCC67463.1 - 2.3e-05 24.3 0.1 6.4e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF2012 PF09430.10 CCC67463.1 - 0.057 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) UPF0086 PF01868.16 CCC67464.1 - 1.8e-24 85.4 0.0 4.1e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function UPF0086 F_actin_bind PF08919.10 CCC67464.1 - 0.075 13.1 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 F-actin binding Cullin PF00888.22 CCC67465.1 - 1.7e-18 66.6 2.5 7.2e-17 61.2 0.7 2.4 2 0 0 2 2 2 2 Cullin family Cullin_Nedd8 PF10557.9 CCC67465.1 - 0.13 12.3 1.0 0.81 9.8 0.0 2.9 4 0 0 4 4 4 0 Cullin protein neddylation domain Urotensin_II PF02083.15 CCC67465.1 - 2.4 8.0 4.4 5 7.0 4.4 1.5 1 0 0 1 1 1 0 Urotensin II Snf7 PF03357.21 CCC67466.1 - 5.9e-11 42.3 20.2 1.9e-10 40.6 20.0 1.9 1 1 0 1 1 1 1 Snf7 GP3_package PF16677.5 CCC67466.1 - 0.038 14.1 0.9 0.33 11.1 0.0 2.6 2 0 0 2 2 2 0 DNA-packaging protein gp3 Gluconate_2-dh3 PF13618.6 CCC67466.1 - 0.13 12.5 1.0 3.5 7.9 0.0 3.0 3 1 0 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 DUF4834 PF16118.5 CCC67467.1 - 0.1 13.6 1.1 0.21 12.6 1.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Amidohydro_2 PF04909.14 CCC67468.1 - 4.5e-26 92.3 0.0 5.5e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase DUF5075 PF16825.5 CCC67468.1 - 0.11 12.2 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 IGP family C-type lectin domain rRNA_proc-arch PF13234.6 CCC67469.1 - 4.3e-81 272.8 1.1 4.3e-81 272.8 1.1 2.3 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 CCC67469.1 - 2.6e-54 183.3 0.6 9.8e-54 181.4 0.6 2.1 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 CCC67469.1 - 7.1e-19 68.2 0.0 1.2e-17 64.3 0.0 2.8 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC67469.1 - 2.6e-06 27.7 0.0 2.5e-05 24.6 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CCC67469.1 - 0.049 13.9 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 CCC67469.1 - 0.065 12.3 0.1 0.18 10.9 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF155 PF02582.14 CCC67469.1 - 0.077 13.1 0.3 0.55 10.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised ACR, YagE family COG1723 Vps26 PF03643.15 CCC67471.1 - 2e-111 371.4 0.0 2.4e-111 371.2 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 CCC67471.1 - 0.0074 16.3 0.4 0.11 12.5 0.7 2.5 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Rgp1 PF08737.10 CCC67471.1 - 0.079 12.1 1.9 7.5 5.6 0.2 2.4 1 1 0 2 2 2 0 Rgp1 Tim54 PF11711.8 CCC67472.1 - 1.9e-129 431.8 0.6 2.1e-129 431.6 0.6 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DUF4650 PF15509.6 CCC67472.1 - 0.0075 15.6 0.1 0.012 15.0 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4650) EphA2_TM PF14575.6 CCC67472.1 - 0.1 13.5 0.3 0.25 12.2 0.3 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Lysine_decarbox PF03641.14 CCC67473.1 - 6.6e-45 152.4 0.2 8.2e-45 152.1 0.2 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 CCC67473.1 - 1.8e-12 47.1 0.1 4.4e-12 45.8 0.1 1.6 1 1 0 1 1 1 1 SLOG cluster4 family zf-H2C2_2 PF13465.6 CCC67474.1 - 8e-26 89.3 44.1 2.4e-07 30.8 0.7 7.7 7 0 0 7 7 7 5 Zinc-finger double domain zf-C2H2 PF00096.26 CCC67474.1 - 1.2e-23 82.2 67.6 2.2e-05 24.7 0.4 9.0 9 0 0 9 9 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC67474.1 - 6.8e-14 51.4 80.9 0.00044 20.9 1.4 9.7 11 0 0 11 11 8 7 C2H2-type zinc finger Zap1_zf2 PF18217.1 CCC67474.1 - 1.8e-10 40.6 13.8 1.8e-10 40.6 13.8 5.8 6 0 0 6 6 5 1 Zap1 zinc finger 2 FOXP-CC PF16159.5 CCC67474.1 - 5.8e-07 30.1 34.6 0.049 14.3 0.2 7.2 5 2 1 6 6 6 4 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 CCC67474.1 - 2.2e-06 27.5 39.1 0.0065 16.4 0.9 7.6 6 1 1 7 7 7 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCC67474.1 - 5.2e-05 23.4 2.7 5.2e-05 23.4 2.7 7.7 9 0 0 9 9 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_8 PF15909.5 CCC67474.1 - 0.00015 22.0 26.4 0.43 10.9 1.6 5.2 2 1 2 4 4 4 3 C2H2-type zinc ribbon zf-C2HC_2 PF13913.6 CCC67474.1 - 0.00016 21.5 18.5 0.13 12.2 0.8 5.3 5 0 0 5 5 5 3 zinc-finger of a C2HC-type zf-met PF12874.7 CCC67474.1 - 0.002 18.4 2.4 0.002 18.4 2.4 7.3 8 0 0 8 8 8 3 Zinc-finger of C2H2 type zf_ZIC PF18366.1 CCC67474.1 - 0.091 12.9 0.0 0.091 12.9 0.0 5.6 6 0 0 6 6 6 0 Zic proteins zinc finger domain GAGA PF09237.11 CCC67474.1 - 7.6 6.4 7.6 1.7 8.5 0.2 3.0 1 1 1 3 3 3 0 GAGA factor Pkinase PF00069.25 CCC67475.1 - 1.1e-31 110.2 0.0 4.3e-30 105.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67475.1 - 9.7e-17 61.1 0.0 8.8e-16 58.0 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC67475.1 - 0.00014 20.8 0.0 0.00027 19.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CCC67475.1 - 0.018 14.4 0.0 0.49 9.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 CCC67475.1 - 0.034 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family HbrB PF08539.11 CCC67476.1 - 4.9e-19 68.9 6.0 4.9e-19 68.9 6.0 3.5 2 2 0 2 2 2 1 HbrB-like CLN3 PF02487.17 CCC67477.1 - 3.7e-142 474.1 16.5 4.2e-142 473.9 16.5 1.0 1 0 0 1 1 1 1 CLN3 protein Aminotran_1_2 PF00155.21 CCC67478.1 - 2.9e-86 289.9 0.0 3.6e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CCC67478.1 - 0.00082 18.0 0.2 0.0025 16.4 0.2 1.7 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 CCC67478.1 - 0.0016 17.8 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CCC67478.1 - 0.015 14.3 0.2 0.036 13.0 0.2 1.6 1 1 0 1 1 1 0 Aminotransferase class-V Aminotran_3 PF00202.21 CCC67478.1 - 0.054 12.1 0.1 0.087 11.5 0.1 1.2 1 0 0 1 1 1 0 Aminotransferase class-III DUF2240 PF09999.9 CCC67478.1 - 0.06 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) DUF1993 PF09351.10 CCC67479.1 - 0.31 11.1 3.2 1.2 9.3 0.4 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1993) DUF2203 PF09969.9 CCC67479.1 - 8.7 7.1 7.8 8.1 7.2 1.5 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Phosphodiest PF01663.22 CCC67480.1 - 3.3e-12 46.7 5.1 1.2e-08 35.0 0.9 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CCC67480.1 - 7.8e-05 22.1 0.3 0.00014 21.4 0.3 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 CCC67480.1 - 0.022 14.2 0.1 0.042 13.2 0.1 1.6 1 0 0 1 1 1 0 Sulfatase CBFD_NFYB_HMF PF00808.23 CCC67481.1 - 0.0032 17.7 0.0 0.017 15.4 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MPM1 PF17234.2 CCC67482.1 - 1.5e-47 162.1 4.4 1.5e-47 162.1 4.4 1.6 2 0 0 2 2 2 1 Mitochondrial peculiar membrane protein 1 Esterase PF00756.20 CCC67483.1 - 1.9e-56 191.5 0.1 2.2e-56 191.3 0.1 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 CCC67483.1 - 0.0004 19.9 0.0 0.00062 19.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CCC67483.1 - 0.0062 15.8 0.0 0.034 13.4 0.0 1.9 1 1 1 2 2 2 1 Serine aminopeptidase, S33 WD40 PF00400.32 CCC67484.1 - 1.2e-13 51.3 0.0 0.0012 19.6 0.0 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC67484.1 - 1.8e-08 34.6 0.0 0.039 14.2 0.0 4.3 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Spc42p PF11544.8 CCC67485.1 - 1.6e-09 37.6 9.2 1.6e-09 37.6 9.2 3.2 2 1 1 3 3 3 1 Spindle pole body component Spc42p TSC22 PF01166.18 CCC67485.1 - 0.024 15.0 2.1 0.024 15.0 2.1 3.7 4 0 0 4 4 4 0 TSC-22/dip/bun family DUF3970 PF13113.6 CCC67485.1 - 6.1 7.1 8.0 73 3.7 4.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) MCC-bdg_PDZ PF10506.9 CCC67485.1 - 6.3 6.9 9.6 16 5.6 0.4 3.3 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF1664 PF07889.12 CCC67485.1 - 8.4 6.5 12.6 0.1 12.6 3.2 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) HCO3_cotransp PF00955.21 CCC67486.1 - 0.57 8.9 2.5 1.2 7.9 2.5 1.5 1 0 0 1 1 1 0 HCO3- transporter family A_deaminase PF00962.22 CCC67487.1 - 3.3e-21 76.0 0.0 1.2e-09 37.9 0.0 3.2 3 0 0 3 3 3 3 Adenosine/AMP deaminase NAT PF04768.13 CCC67488.1 - 3e-48 163.7 0.2 8.7e-48 162.2 0.2 1.7 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Sld5 PF05916.11 CCC67489.1 - 4.2e-18 65.8 1.9 8.7e-18 64.8 1.9 1.5 1 0 0 1 1 1 1 GINS complex protein DUF4260 PF14079.6 CCC67489.1 - 0.032 14.2 0.0 0.056 13.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4260) DnaJ PF00226.31 CCC67490.1 - 8.7e-20 70.6 4.2 8.7e-20 70.6 4.2 2.2 2 0 0 2 2 2 1 DnaJ domain TFIIA PF03153.13 CCC67490.1 - 0.028 14.4 19.1 0.037 14.0 19.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 CCC67490.1 - 2.2 7.5 10.4 3.8 6.8 10.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1266 PF06889.11 CCC67490.1 - 2.8 8.0 7.6 10 6.1 7.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1266) SMC_N PF02463.19 CCC67491.1 - 3.1e-54 183.7 51.8 1e-53 182.0 51.8 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCC67491.1 - 7e-29 100.5 0.0 5.2e-28 97.7 0.0 2.6 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CCC67491.1 - 1.3e-18 68.2 4.5 1.3e-18 68.2 4.5 6.8 3 2 4 7 7 7 1 AAA domain AAA_21 PF13304.6 CCC67491.1 - 1.1e-11 45.1 4.9 2.6e-07 30.8 2.8 4.6 3 2 2 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CCC67491.1 - 5.6e-05 23.0 102.8 7.4e-05 22.6 49.1 4.8 1 1 1 2 2 2 1 AAA ATPase domain BRCT PF00533.26 CCC67491.1 - 0.00068 20.0 0.4 7.9 6.9 0.0 4.6 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain AAA_29 PF13555.6 CCC67491.1 - 0.0085 15.8 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Cytokin_check_N PF10407.9 CCC67492.1 - 1e-28 99.1 1.3 2.8e-28 97.6 1.3 1.8 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus CAP PF00188.26 CCC67493.1 - 2.6e-18 67.1 2.4 5.3e-18 66.1 2.4 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF1326 PF07040.11 CCC67493.1 - 0.13 12.3 0.5 0.19 11.8 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1326) KH_1 PF00013.29 CCC67494.1 - 4.3e-84 276.3 29.3 3.1e-14 52.6 0.5 11.9 12 0 0 12 12 12 8 KH domain KH_2 PF07650.17 CCC67494.1 - 6.3e-11 41.9 21.1 0.0004 20.2 0.1 7.0 6 1 0 7 7 7 3 KH domain KH_5 PF13184.6 CCC67494.1 - 1.2e-06 28.5 14.2 0.34 11.0 0.2 7.4 7 0 0 7 7 7 2 NusA-like KH domain SLS PF14611.6 CCC67494.1 - 1.1e-05 25.4 17.4 0.18 11.6 1.2 5.9 4 2 2 6 6 6 3 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 CCC67494.1 - 0.00093 19.0 3.1 2.5 8.0 0.0 5.4 4 0 0 4 4 4 1 KH domain STAS PF01740.21 CCC67494.1 - 0.003 17.2 0.1 0.013 15.1 0.0 2.1 2 0 0 2 2 2 1 STAS domain DUF948 PF06103.11 CCC67494.1 - 1.5 9.2 5.6 17 5.8 0.0 4.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Matrilin_ccoil PF10393.9 CCC67494.1 - 1.9 8.4 3.9 2.8 7.9 0.1 3.0 3 0 0 3 3 3 0 Trimeric coiled-coil oligomerisation domain of matrilin Laminin_II PF06009.12 CCC67494.1 - 8.3 6.4 13.8 3.5 7.6 0.4 4.8 4 1 0 4 4 4 0 Laminin Domain II EF-hand_4 PF12763.7 CCC67495.1 - 0.0064 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Arrestin_C PF02752.22 CCC67496.1 - 6.5e-13 49.3 0.5 6.2e-12 46.1 0.1 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCC67496.1 - 8.5e-06 25.9 0.0 0.0011 19.0 0.1 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Exo70 PF03081.15 CCC67497.1 - 2.5e-87 293.4 8.9 7.1e-87 291.9 4.8 2.1 2 0 0 2 2 2 2 Exo70 exocyst complex subunit Vps51 PF08700.11 CCC67497.1 - 0.037 14.1 2.1 0.19 11.8 0.1 2.9 2 0 0 2 2 2 0 Vps51/Vps67 OTCace PF00185.24 CCC67498.1 - 2.8e-49 167.2 0.5 5.8e-49 166.2 0.5 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 CCC67498.1 - 1.8e-41 141.6 0.1 3.4e-41 140.7 0.1 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Zn_clus PF00172.18 CCC67499.1 - 1.3e-08 34.8 12.4 2.7e-08 33.8 12.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRCT PF00533.26 CCC67500.1 - 1.7e-17 63.6 2.8 1.1e-06 28.9 0.0 4.4 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CCC67500.1 - 2.8e-11 43.2 0.4 4.5e-06 26.5 0.0 4.3 4 0 0 4 4 4 3 twin BRCT domain BRCT_2 PF16589.5 CCC67500.1 - 4.6e-11 43.0 0.2 0.00023 21.5 0.0 3.7 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT_3 PF18428.1 CCC67500.1 - 7.8e-06 25.9 0.0 0.00014 21.9 0.0 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain NIBRIN_BRCT_II PF16508.5 CCC67500.1 - 0.013 15.9 0.8 0.037 14.3 0.0 2.2 3 0 0 3 3 3 0 Second BRCT domain on Nijmegen syndrome breakage protein GWT1 PF06423.12 CCC67501.1 - 4.9e-39 133.8 4.2 8.6e-39 133.0 3.2 2.0 2 0 0 2 2 2 1 GWT1 DUF4818 PF16089.5 CCC67501.1 - 0.019 15.4 0.7 0.077 13.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4818) DUF4010 PF13194.6 CCC67501.1 - 0.022 14.4 0.0 0.1 12.3 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4010) UvrD-helicase PF00580.21 CCC67502.1 - 9.9e-63 212.5 0.1 9.9e-63 212.5 0.1 3.1 3 1 0 3 3 2 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 CCC67502.1 - 2.3e-38 132.5 1.2 5.4e-38 131.3 0.0 2.3 2 1 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 CCC67502.1 - 1.2e-30 106.8 0.0 3.9e-30 105.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 CCC67502.1 - 1.5e-08 34.4 0.1 0.00021 21.1 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 CCC67502.1 - 1.6e-05 24.8 0.0 1.6e-05 24.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 CCC67502.1 - 6.7e-05 22.7 0.0 0.0025 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 CCC67502.1 - 0.017 15.0 0.0 0.049 13.5 0.0 1.8 1 0 0 1 1 1 0 Helicase DEAD PF00270.29 CCC67502.1 - 0.021 14.6 0.1 0.43 10.3 0.0 2.5 2 0 0 2 2 2 0 DEAD/DEAH box helicase GatB_Yqey PF02637.18 CCC67502.1 - 0.052 13.4 0.0 0.22 11.4 0.0 2.2 1 1 0 1 1 1 0 GatB domain ResIII PF04851.15 CCC67502.1 - 0.086 12.8 1.1 0.27 11.2 0.0 2.5 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF4611 PF15387.6 CCC67502.1 - 0.61 10.3 3.6 2.5 8.4 3.6 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Ion_trans_2 PF07885.16 CCC67503.1 - 1.5e-23 82.5 27.8 1.9e-14 53.3 10.1 3.4 4 0 0 4 4 4 2 Ion channel Lig_chan PF00060.26 CCC67503.1 - 0.14 12.0 9.2 12 5.8 0.1 3.8 2 2 1 3 3 3 0 Ligand-gated ion channel Roughex PF06020.11 CCC67503.1 - 0.19 10.8 0.0 0.32 10.1 0.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Na_H_Exchanger PF00999.21 CCC67504.1 - 6.4e-56 189.8 35.2 8.9e-56 189.3 35.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Clathrin-link PF09268.10 CCC67504.1 - 0.08 12.3 0.0 0.26 10.7 0.0 1.9 1 0 0 1 1 1 0 Clathrin, heavy-chain linker putAbiC PF16872.5 CCC67504.1 - 0.16 12.7 1.2 0.38 11.5 1.2 1.7 1 0 0 1 1 1 0 Putative phage abortive infection protein Pkinase PF00069.25 CCC67505.1 - 5.2e-67 226.0 0.0 1e-66 225.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67505.1 - 1.9e-44 151.9 0.0 3.4e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC67505.1 - 8.6e-11 41.7 0.0 1.4e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CCC67505.1 - 0.023 13.5 0.0 0.023 13.5 0.0 3.1 3 1 0 3 3 3 0 Fungal protein kinase APH PF01636.23 CCC67505.1 - 0.093 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CCC67505.1 - 0.13 11.6 0.0 0.26 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L21p PF00829.21 CCC67506.1 - 1.2e-11 44.8 0.1 1.5e-11 44.4 0.1 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein DUF4378 PF14309.6 CCC67506.1 - 0.15 12.5 0.0 5 7.5 0.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4378) PTPLA PF04387.14 CCC67507.1 - 3.6e-50 169.9 11.9 4.8e-50 169.5 11.9 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF2070 PF09843.9 CCC67507.1 - 6.5 4.9 7.9 6.6 4.9 7.9 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SAPS PF04499.15 CCC67508.1 - 4.5e-171 569.9 0.6 4.5e-171 569.9 0.6 3.5 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Arm PF00514.23 CCC67508.1 - 0.0057 16.7 0.0 0.023 14.7 0.0 2.1 1 0 0 1 1 1 1 Armadillo/beta-catenin-like repeat ChAPs PF09295.10 CCC67509.1 - 1e-43 149.9 4.0 1.9e-35 122.6 0.4 2.2 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 CCC67509.1 - 0.0002 21.2 1.3 0.15 12.2 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC67509.1 - 0.0055 16.9 0.6 0.045 14.0 0.2 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CCC67509.1 - 0.009 16.0 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCC67509.1 - 0.011 15.5 0.5 0.15 12.0 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCC67509.1 - 0.083 13.4 0.0 0.37 11.4 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 CCC67509.1 - 0.086 13.3 0.1 0.43 11.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.27 CCC67510.1 - 1.2e-56 192.4 0.0 2e-56 191.6 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GTP_EFTU PF00009.27 CCC67511.1 - 6.3e-61 205.3 0.1 1e-60 204.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.6 CCC67511.1 - 2.4e-25 88.4 0.1 5.7e-25 87.2 0.1 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CCC67511.1 - 3.8e-14 52.5 0.1 5.6e-09 35.9 0.0 2.5 2 0 0 2 2 2 2 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCC67511.1 - 9.5e-12 45.1 0.9 2.8e-11 43.6 0.9 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CCC67511.1 - 0.00026 20.8 0.0 0.00052 19.8 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 CCC67511.1 - 0.0004 20.4 0.0 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zn_clus PF00172.18 CCC67512.1 - 8.9e-06 25.7 12.1 1.8e-05 24.7 12.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.7 CCC67512.1 - 0.027 14.7 0.2 0.45 10.8 0.0 2.3 2 0 0 2 2 2 0 PAS domain PAS PF00989.25 CCC67512.1 - 0.037 14.0 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 PAS fold Pam16 PF03656.13 CCC67513.1 - 5.4e-52 175.1 0.1 6.5e-52 174.9 0.1 1.0 1 0 0 1 1 1 1 Pam16 NTP_transferase PF00483.23 CCC67513.1 - 0.036 13.6 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase CAP_N PF01213.19 CCC67513.1 - 0.052 13.0 2.7 0.073 12.5 2.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal STb_secrete PF09075.10 CCC67513.1 - 0.078 13.0 0.3 0.88 9.7 0.0 2.2 1 1 1 2 2 2 0 Heat-stable enterotoxin B, secretory SET PF00856.28 CCC67514.1 - 5.8e-06 26.8 0.2 6.3e-05 23.4 0.0 2.6 2 1 0 2 2 2 1 SET domain PHD PF00628.29 CCC67514.1 - 0.0004 20.2 8.1 0.0011 18.8 8.1 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CCC67514.1 - 0.014 14.9 4.9 0.037 13.6 4.9 1.7 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 CCC67514.1 - 1.4 8.9 8.2 0.17 11.9 3.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Pkinase PF00069.25 CCC67515.1 - 6.4e-53 179.8 0.1 4.8e-51 173.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67515.1 - 7.1e-27 94.3 0.1 7.6e-26 90.9 0.1 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.11 CCC67515.1 - 0.00012 21.2 1.2 0.00017 20.7 0.2 1.6 1 1 1 2 2 2 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 CCC67515.1 - 0.0073 15.7 0.3 0.013 14.9 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_lig_T4_1 PF09511.10 CCC67516.1 - 1.6e-77 260.3 0.0 3.3e-77 259.3 0.0 1.6 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.11 CCC67516.1 - 1.6e-72 243.0 0.5 2e-71 239.5 0.0 2.7 3 0 0 3 3 3 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.11 CCC67516.1 - 1.7e-61 207.9 3.6 2.3e-61 207.4 3.6 1.2 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain LigT_PEase PF02834.16 CCC67516.1 - 0.18 12.1 0.0 33 4.8 0.0 2.7 2 0 0 2 2 2 0 LigT like Phosphoesterase BP28CT PF08146.12 CCC67517.1 - 2.5e-37 128.2 3.1 2.9e-36 124.7 3.1 3.1 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 CCC67517.1 - 1.5e-19 70.4 1.7 1.5e-19 70.4 1.7 5.9 5 1 0 5 5 5 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.6 CCC67517.1 - 0.0066 16.8 0.3 2.4 8.6 0.0 4.2 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.22 CCC67517.1 - 0.26 11.7 3.5 25 5.5 0.3 4.5 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.6 CCC67517.1 - 0.38 11.3 1.1 48 4.6 0.2 3.3 2 0 0 2 2 2 0 HEAT-like repeat GATA PF00320.27 CCC67518.1 - 2.1e-14 52.8 3.2 3.7e-14 52.0 3.2 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CCC67518.1 - 0.0052 16.3 0.5 0.01 15.3 0.5 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Auto_anti-p27 PF06677.12 CCC67518.1 - 0.2 11.9 0.5 0.34 11.1 0.5 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) M-factor PF03855.13 CCC67518.1 - 0.43 10.8 2.9 29 4.9 0.2 3.0 2 0 0 2 2 2 0 M-factor WD40 PF00400.32 CCC67519.1 - 9.8e-27 92.7 18.0 6e-07 30.1 0.2 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Caf4 PF11615.8 CCC67519.1 - 2.9e-08 33.6 0.4 2.7e-05 24.1 0.4 2.8 1 1 0 1 1 1 1 CCR4-associated factor 4 ANAPC4_WD40 PF12894.7 CCC67519.1 - 4.5e-07 30.1 0.2 0.0083 16.4 0.0 4.7 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCC67519.1 - 1.6e-06 27.7 0.4 0.0045 16.4 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Nup160 PF11715.8 CCC67519.1 - 4.4e-05 22.3 6.0 0.19 10.4 0.0 4.8 1 1 4 5 5 5 3 Nucleoporin Nup120/160 DUF5046 PF16465.5 CCC67519.1 - 0.0007 19.1 0.1 0.0032 17.0 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF5046) Mcl1_mid PF12341.8 CCC67519.1 - 0.038 13.3 0.1 0.52 9.6 0.0 2.1 2 0 0 2 2 2 0 Minichromosome loss protein, Mcl1, middle region DUF16 PF01519.16 CCC67519.1 - 0.089 13.3 1.6 0.26 11.8 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function DUF16 RT_RNaseH PF17917.1 CCC67520.1 - 1.9e-09 37.8 0.0 2e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CCC67520.1 - 9.5e-08 32.0 0.0 1.1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DUF4107 PF13389.6 CCC67521.1 - 0.021 15.0 1.5 0.031 14.4 0.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4107) DUF848 PF05852.11 CCC67521.1 - 0.14 12.3 7.3 1.4 9.0 6.8 2.3 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Tape_meas_lam_C PF09718.10 CCC67521.1 - 0.15 12.2 1.6 0.16 12.1 0.3 1.6 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Golgin_A5 PF09787.9 CCC67521.1 - 0.16 11.4 9.8 0.2 11.1 9.8 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3573 PF12097.8 CCC67521.1 - 1.5 7.6 6.7 2 7.2 6.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) KCNQ2_u3 PF16642.5 CCC67522.1 - 0.23 12.5 7.1 0.53 11.3 7.1 1.6 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 RP-C_C PF11800.8 CCC67522.1 - 2 8.5 4.2 5.7 7.0 2.8 2.1 2 0 0 2 2 2 0 Replication protein C C-terminal region ASF1_hist_chap PF04729.13 CCC67523.1 - 8.9e-72 240.1 0.0 1.3e-71 239.5 0.0 1.3 1 0 0 1 1 1 1 ASF1 like histone chaperone Mpp10 PF04006.12 CCC67523.1 - 0.064 11.7 34.2 0.08 11.4 34.2 1.1 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 CCC67523.1 - 0.3 9.3 31.2 0.39 9.0 31.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CCC67523.1 - 0.45 8.7 39.4 0.54 8.4 39.4 1.1 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 CCC67523.1 - 0.5 9.7 36.5 0.56 9.5 36.5 1.1 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 CCC67523.1 - 0.93 8.9 40.0 1.2 8.5 40.0 1.3 1 0 0 1 1 1 0 SDA1 DUF2722 PF10846.8 CCC67523.1 - 8.4 5.2 17.8 11 4.9 17.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SUN PF03856.13 CCC67524.1 - 6.8e-97 323.7 11.1 9.5e-97 323.2 11.1 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) IL2 PF00715.17 CCC67524.1 - 0.066 13.1 0.6 1.7 8.6 0.2 2.3 2 0 0 2 2 2 0 Interleukin 2 zf-MYND PF01753.18 CCC67524.1 - 0.27 11.4 2.3 0.61 10.2 2.3 1.5 1 0 0 1 1 1 0 MYND finger Pho86 PF11124.8 CCC67525.1 - 3.9e-105 351.5 4.6 4.4e-105 351.3 4.6 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 DUF3539 PF12058.8 CCC67525.1 - 0.0023 18.0 0.3 0.005 16.9 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3539) GIDA PF01134.22 CCC67525.1 - 0.08 12.0 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Ribul_P_3_epim PF00834.19 CCC67526.1 - 2.3e-70 236.0 0.0 2.7e-70 235.8 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.24 CCC67526.1 - 0.0092 15.6 0.1 0.024 14.2 0.0 1.6 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.19 CCC67526.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Alb1 PF09135.11 CCC67527.1 - 4.8e-18 66.0 9.3 4.8e-18 66.0 9.3 1.7 2 0 0 2 2 2 1 Alb1 DUF5427 PF10310.9 CCC67528.1 - 2.7e-119 399.2 29.7 3.2e-119 399.0 29.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5427) DUF885 PF05960.11 CCC67528.1 - 0.011 15.5 1.6 0.018 14.7 1.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Cyc-maltodext_C PF10438.9 CCC67528.1 - 0.024 14.7 0.3 0.074 13.2 0.3 1.8 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain DUF2894 PF11445.8 CCC67528.1 - 0.099 13.1 6.4 0.036 14.6 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) Pol_alpha_B_N PF08418.10 CCC67528.1 - 0.55 10.1 23.4 0.26 11.2 19.0 2.5 2 1 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal Phi_1 PF04674.12 CCC67528.1 - 1.8 7.8 9.4 0.17 11.1 3.0 2.2 1 1 1 2 2 2 0 Phosphate-induced protein 1 conserved region GCD14 PF08704.10 CCC67529.1 - 8.6e-83 277.8 0.1 3.2e-82 275.9 0.1 1.8 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 CCC67529.1 - 0.00011 22.0 0.0 0.00022 21.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 CCC67529.1 - 0.00046 19.3 0.0 0.00096 18.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase GCD14_N PF14801.6 CCC67529.1 - 0.00087 19.1 0.8 0.0092 15.8 0.0 2.7 3 0 0 3 3 3 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_25 PF13649.6 CCC67529.1 - 0.0013 19.4 0.0 0.0032 18.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Gcd10p PF04189.13 CCC67529.1 - 0.036 13.2 0.8 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 Gcd10p family Methyltransf_23 PF13489.6 CCC67529.1 - 0.045 13.6 0.6 0.27 11.1 0.6 2.1 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CCC67529.1 - 0.068 12.9 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ta0938 PF11494.8 CCC67529.1 - 0.11 12.8 0.0 0.41 10.9 0.0 1.9 1 0 0 1 1 1 0 Ta0938 CN_hydrolase PF00795.22 CCC67530.1 - 6.6e-51 173.1 0.0 7.5e-51 173.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Guanylate_cyc PF00211.20 CCC67530.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Adenylate and Guanylate cyclase catalytic domain zf-H2C2 PF09337.10 CCC67531.1 - 1.5e-14 53.9 3.0 2.5e-14 53.2 3.0 1.4 1 0 0 1 1 1 1 H2C2 zinc finger Integrase_H2C2 PF17921.1 CCC67531.1 - 6.6e-10 38.9 2.0 1.2e-09 38.1 2.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain Acetyltransf_1 PF00583.25 CCC67531.1 - 0.00035 20.8 0.0 0.00035 20.8 0.0 3.0 4 0 0 4 4 4 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCC67531.1 - 0.031 14.2 0.2 11 6.0 0.0 2.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RNA_pol_3_Rpc31 PF11705.8 CCC67531.1 - 0.04 14.2 18.3 0.096 12.9 18.3 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.13 CCC67531.1 - 0.045 13.7 15.2 0.083 12.9 15.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YL1 PF05764.13 CCC67531.1 - 0.66 10.0 24.8 1.8 8.6 24.8 1.7 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 CCC67531.1 - 1.2 7.3 23.1 1.7 6.8 23.1 1.2 1 0 0 1 1 1 0 Nop14-like family Myc_N PF01056.18 CCC67531.1 - 1.7 8.5 8.5 3.3 7.5 8.5 1.5 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.12 CCC67531.1 - 1.8 7.8 21.5 4.3 6.6 21.5 1.6 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.13 CCC67531.1 - 2.6 7.9 16.9 5.1 6.9 16.9 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region CDC45 PF02724.14 CCC67531.1 - 2.7 6.2 17.8 5.3 5.2 17.8 1.4 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 CCC67531.1 - 3.8 5.8 26.0 7.2 4.9 26.0 1.4 1 0 0 1 1 1 0 Mpp10 protein BUD22 PF09073.10 CCC67531.1 - 4 6.7 19.5 0.9 8.8 16.2 1.7 2 0 0 2 2 2 0 BUD22 PPP4R2 PF09184.11 CCC67531.1 - 4.4 6.8 22.0 11 5.5 22.0 1.6 1 0 0 1 1 1 0 PPP4R2 SDA1 PF05285.12 CCC67531.1 - 4.4 6.6 22.4 7.8 5.8 22.4 1.4 1 0 0 1 1 1 0 SDA1 Usp PF00582.26 CCC67531.1 - 5.1 7.6 6.3 10 6.6 6.3 1.5 1 0 0 1 1 1 0 Universal stress protein family DUF5310 PF17237.2 CCC67532.1 - 1.5e-24 85.6 2.3 1.7e-24 85.4 2.3 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5310) Pkinase PF00069.25 CCC67533.1 - 1.4e-60 204.9 0.1 3.1e-60 203.8 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67533.1 - 1.6e-36 125.9 0.0 3e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC67533.1 - 0.00027 20.3 0.0 0.00058 19.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CCC67533.1 - 0.0056 15.8 0.1 0.0056 15.8 0.1 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 CCC67533.1 - 0.41 9.3 0.0 0.41 9.3 0.0 2.8 2 1 0 2 2 2 0 Fungal protein kinase SCIMP PF15050.6 CCC67533.1 - 0.54 10.7 5.0 1.4 9.4 4.3 2.1 1 1 0 1 1 1 0 SCIMP protein PIEZO PF15917.5 CCC67533.1 - 6.2 6.2 12.4 0.7 9.3 2.2 2.3 2 0 0 2 2 2 0 Piezo LMBR1 PF04791.16 CCC67533.1 - 7.7 5.3 7.0 13 4.5 7.0 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein TrkH PF02386.16 CCC67534.1 - 2.6e-175 583.7 1.1 7.8e-174 578.8 0.0 2.1 2 0 0 2 2 2 2 Cation transport protein CPSase_L_D2 PF02786.17 CCC67535.1 - 4.6e-115 382.4 1.4 5.2e-84 281.0 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 CCC67535.1 - 2e-48 163.5 0.0 4.7e-48 162.3 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 CCC67535.1 - 1.6e-45 154.8 0.0 3.6e-45 153.6 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 CCC67535.1 - 1.3e-44 152.3 0.0 3.5e-44 150.9 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 CCC67535.1 - 1.7e-38 131.7 0.1 7.3e-38 129.6 0.1 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 CCC67535.1 - 4.4e-31 108.1 0.4 6.7e-30 104.2 0.0 3.0 3 0 0 3 3 3 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain MGS PF02142.22 CCC67535.1 - 4.3e-22 78.1 0.0 2.5e-21 75.7 0.0 2.5 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.13 CCC67535.1 - 1e-18 67.6 3.3 1.6e-10 40.9 0.4 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CCC67535.1 - 2e-15 56.8 0.9 2.6e-07 30.4 0.2 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CCC67535.1 - 6.5e-12 45.3 0.1 7.4e-07 29.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 CCC67535.1 - 6.3e-06 26.3 1.6 0.016 15.3 0.3 2.9 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 CCC67535.1 - 0.00017 21.4 0.0 0.014 15.2 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 RimK PF08443.11 CCC67535.1 - 0.00026 20.7 0.3 0.14 11.8 0.2 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain DJ-1_PfpI PF01965.24 CCC67535.1 - 0.0029 17.4 0.4 0.3 10.9 0.0 3.9 5 0 0 5 5 5 1 DJ-1/PfpI family GARS_A PF01071.19 CCC67535.1 - 0.011 15.5 1.3 1.6 8.5 0.1 3.3 3 1 0 3 3 3 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 CCC67535.1 - 0.09 12.2 0.4 9.3 5.6 0.0 2.5 2 0 0 2 2 2 0 ATP-grasp domain TrkA_N PF02254.18 CCC67535.1 - 0.41 10.9 3.4 0.31 11.3 0.1 2.6 3 0 0 3 3 2 0 TrkA-N domain mIF3 PF14877.6 CCC67536.1 - 2.2e-62 209.8 11.3 2.2e-62 209.8 11.3 2.1 2 0 0 2 2 2 1 Mitochondrial translation initiation factor DUF1018 PF06252.12 CCC67536.1 - 0.033 15.2 0.9 0.033 15.2 0.9 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1018) Zn_dep_PLPC PF00882.18 CCC67537.1 - 3.7e-25 88.9 1.5 6.7e-25 88.1 1.5 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C Mito_carr PF00153.27 CCC67538.1 - 5.9e-62 205.6 3.7 4.4e-22 77.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein AhpC-TSA_2 PF13911.6 CCC67538.1 - 0.0089 16.1 0.0 0.012 15.7 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Serine_protease PF18405.1 CCC67538.1 - 0.039 13.1 2.6 0.82 8.8 0.4 2.7 1 1 1 2 2 2 0 Gammaproteobacterial serine protease Ribosomal_L27A PF00828.19 CCC67539.1 - 1.1e-32 113.4 3.8 1.1e-32 113.4 1.4 2.0 2 0 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF1604 PF07713.13 CCC67539.1 - 0.099 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) Acetyltransf_1 PF00583.25 CCC67540.1 - 9.9e-13 48.4 0.4 1.2e-12 48.1 0.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCC67540.1 - 2.4e-07 30.7 0.1 3.4e-07 30.2 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCC67540.1 - 2.7e-06 27.7 0.1 3.3e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CCC67540.1 - 2e-05 25.3 0.3 2.5e-05 25.0 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CCC67540.1 - 0.00037 20.7 0.1 0.00045 20.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCC67540.1 - 0.0053 16.7 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 CCC67540.1 - 0.0056 16.8 0.0 0.013 15.6 0.0 1.6 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 CCC67540.1 - 0.0078 16.3 0.1 0.017 15.2 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 CCC67540.1 - 0.026 14.3 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain, PanZ RRM_1 PF00076.22 CCC67541.1 - 4.6e-19 68.0 0.3 1.5e-10 40.8 0.1 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCC67541.1 - 0.0071 16.2 0.2 0.036 13.9 0.0 2.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif Adaptin_N PF01602.20 CCC67542.1 - 1.5e-109 366.9 15.5 2e-109 366.5 15.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 CCC67542.1 - 2e-48 164.4 2.7 5.6e-48 162.9 2.7 1.9 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 CCC67542.1 - 1.3e-27 96.2 0.1 4.3e-27 94.5 0.1 2.0 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CCC67542.1 - 5.2e-11 42.8 0.0 7.8e-06 26.2 0.0 3.9 3 1 1 4 4 4 2 HEAT repeats Cnd1 PF12717.7 CCC67542.1 - 2.3e-05 24.5 9.4 0.004 17.2 0.1 4.0 3 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCC67542.1 - 0.0089 16.2 0.9 39 4.9 0.0 5.5 6 0 0 6 6 6 0 HEAT repeat Rcd1 PF04078.13 CCC67543.1 - 1.6e-112 375.0 4.3 2.1e-112 374.7 4.3 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like SRX PF09201.10 CCC67543.1 - 0.019 14.8 0.1 0.2 11.5 0.1 2.2 2 0 0 2 2 2 0 SRX, signal recognition particle receptor alpha subunit Dimer_Tnp_hAT PF05699.14 CCC67544.1 - 8.1e-09 35.2 0.1 2.8e-08 33.4 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CCC67544.1 - 0.18 11.9 0.5 0.47 10.5 0.5 1.8 1 0 0 1 1 1 0 BED zinc finger Cyclin_N PF00134.23 CCC67545.1 - 1.4e-22 79.8 0.0 2.4e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCC67545.1 - 7.7e-08 32.9 0.5 1.8e-07 31.6 0.0 1.8 2 1 0 2 2 2 1 Cyclin MHC_II_alpha PF00993.20 CCC67546.1 - 0.03 14.0 0.4 0.084 12.6 0.1 1.9 2 0 0 2 2 2 0 Class II histocompatibility antigen, alpha domain AAA PF00004.29 CCC67547.1 - 9.8e-18 64.9 0.0 1.8e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 CCC67547.1 - 2.5e-16 59.9 0.0 4.7e-13 49.2 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 CCC67547.1 - 9.8e-14 51.5 0.2 3.6e-13 49.7 0.0 2.0 2 0 0 2 2 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 CCC67547.1 - 6.3e-08 32.8 0.0 3.9e-07 30.2 0.0 2.1 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 CCC67547.1 - 6.4e-07 29.6 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 CCC67547.1 - 4.4e-06 27.2 0.0 8.5e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CCC67547.1 - 9.3e-06 25.5 0.0 2.1e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCC67547.1 - 1.2e-05 25.6 0.3 0.21 11.9 0.0 2.6 1 1 1 2 2 2 2 AAA domain DNA_pol3_delta PF06144.13 CCC67547.1 - 2.5e-05 24.1 0.1 4.2e-05 23.4 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.6 CCC67547.1 - 3.1e-05 23.9 0.0 0.00017 21.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CCC67547.1 - 4e-05 23.6 0.0 9.6e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 CCC67547.1 - 9.5e-05 21.7 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.15 CCC67547.1 - 0.00011 22.3 0.0 0.023 14.7 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCC67547.1 - 0.00012 21.8 0.0 0.00059 19.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 CCC67547.1 - 0.00053 20.0 0.1 0.0026 17.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CCC67547.1 - 0.00065 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCC67547.1 - 0.00091 18.8 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region IstB_IS21 PF01695.17 CCC67547.1 - 0.0013 18.5 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CCC67547.1 - 0.0016 19.0 0.0 0.0039 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 CCC67547.1 - 0.0022 17.8 0.2 0.023 14.5 0.0 2.1 1 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 CCC67547.1 - 0.0028 18.0 0.2 0.15 12.4 0.1 2.5 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CCC67547.1 - 0.0046 16.4 0.0 0.033 13.6 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 CCC67547.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 CCC67547.1 - 0.0094 15.8 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 CCC67547.1 - 0.012 15.2 0.1 0.17 11.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain Methyltransf_31 PF13847.6 CCC67547.1 - 0.029 14.2 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain RNA_helicase PF00910.22 CCC67547.1 - 0.041 14.3 0.0 0.082 13.3 0.0 1.6 1 1 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 CCC67547.1 - 0.043 14.1 0.0 0.098 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 CCC67547.1 - 0.065 12.4 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain PhoH PF02562.16 CCC67547.1 - 0.066 12.6 0.0 6.6 6.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein SNF2_N PF00176.23 CCC67547.1 - 0.068 11.9 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 SNF2 family N-terminal domain ABC_tran PF00005.27 CCC67547.1 - 0.069 13.7 0.0 0.3 11.6 0.0 2.1 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CCC67547.1 - 0.1 12.8 0.2 0.26 11.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 CCC67547.1 - 0.1 12.0 0.0 2.3 7.6 0.0 2.3 1 1 1 2 2 2 0 Bacterial TniB protein DUF2075 PF09848.9 CCC67547.1 - 0.15 11.2 0.1 0.62 9.2 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Mid1 PF12929.7 CCC67548.1 - 1.7e-127 426.2 13.7 2e-127 425.9 13.7 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.22 CCC67548.1 - 0.002 18.8 2.5 0.12 13.0 0.4 2.7 2 1 0 2 2 2 2 Fz domain TruB_N PF01509.18 CCC67549.1 - 9.2e-40 136.4 0.2 4.8e-38 130.9 0.0 2.7 3 0 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 CCC67549.1 - 0.00069 19.7 0.0 0.0021 18.2 0.0 1.8 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PHD_like PF12910.7 CCC67549.1 - 0.016 15.3 1.5 3.5 7.6 0.1 2.7 2 1 0 2 2 2 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system Arc_PepC_II PF06847.11 CCC67549.1 - 1.4 9.5 5.0 3.6 8.2 1.0 2.8 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Sds3 PF08598.11 CCC67549.1 - 1.6 8.7 11.1 0.16 11.9 6.7 1.6 2 0 0 2 2 2 0 Sds3-like RabGAP-TBC PF00566.18 CCC67550.1 - 1.4e-43 149.1 3.5 8.3e-31 107.3 0.0 2.7 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PalH PF08733.10 CCC67551.1 - 5.5e-87 291.9 16.8 7.2e-87 291.5 16.8 1.1 1 0 0 1 1 1 1 PalH/RIM21 Pet20 PF08692.10 CCC67552.1 - 8.3e-35 120.3 1.7 9.9e-35 120.1 0.2 2.0 2 0 0 2 2 2 1 Mitochondrial protein Pet20 COesterase PF00135.28 CCC67552.1 - 0.078 11.8 0.2 0.11 11.4 0.2 1.1 1 0 0 1 1 1 0 Carboxylesterase family DCB PF16213.5 CCC67553.1 - 2.2e-48 164.3 0.3 2.2e-48 164.3 0.3 4.1 4 1 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 CCC67553.1 - 1.5e-35 122.4 17.5 1.7e-35 122.2 4.7 5.2 4 0 0 4 4 4 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Mon2_C PF16206.5 CCC67553.1 - 2e-17 62.7 2.3 3.1e-12 45.5 0.6 3.0 2 1 0 2 2 2 2 C-terminal region of Mon2 protein Pkinase PF00069.25 CCC67554.1 - 4.6e-64 216.3 0.0 8.3e-64 215.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67554.1 - 3.6e-51 174.0 0.0 5.7e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CCC67554.1 - 1.6e-23 82.8 0.2 4.2e-23 81.5 0.2 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 CCC67554.1 - 8.2e-10 39.1 1.7 8.6e-10 39.1 0.2 1.8 2 0 0 2 2 2 1 PH domain Pkinase_fungal PF17667.1 CCC67554.1 - 9.9e-07 27.9 0.1 3.2e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CCC67554.1 - 0.00013 21.4 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCC67554.1 - 0.027 14.4 0.3 0.081 12.8 0.3 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family NTP_transf_2 PF01909.23 CCC67555.1 - 5.1e-18 65.2 0.7 1.7e-17 63.5 0.0 2.3 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CCC67555.1 - 2.1e-15 56.7 1.6 3.2e-15 56.1 0.0 2.3 3 0 0 3 3 3 1 Cid1 family poly A polymerase Polbeta PF18765.1 CCC67555.1 - 0.00043 20.3 0.0 0.00043 20.3 0.0 2.9 4 0 0 4 4 4 1 Polymerase beta, Nucleotidyltransferase Ribosomal_L18 PF17135.4 CCC67557.1 - 1.6e-86 288.5 4.4 1.8e-86 288.3 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CCC67557.1 - 0.0083 16.8 0.2 0.027 15.1 0.2 2.0 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Nudc_N PF14050.6 CCC67557.1 - 0.018 15.0 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. Ribosomal_S19e PF01090.19 CCC67558.1 - 2.2e-53 179.6 0.1 2.5e-53 179.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RRM_1 PF00076.22 CCC67559.1 - 9.4e-34 115.1 0.2 4.5e-17 61.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC67559.1 - 1.9e-12 47.1 0.2 1.5e-06 28.2 0.0 2.9 2 1 0 2 2 2 2 RNA recognition motif ZIP4_domain PF18292.1 CCC67559.1 - 8.6 6.3 8.3 0.22 11.4 1.3 1.8 2 0 0 2 2 2 0 Zinc transporter ZIP4 domain Ras PF00071.22 CCC67560.1 - 6.5e-28 97.4 0.4 2e-22 79.5 0.1 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 CCC67560.1 - 4.9e-17 62.2 0.2 7.3e-10 39.1 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC67560.1 - 2.1e-06 27.3 0.5 0.00017 21.1 0.2 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCC67560.1 - 0.055 13.5 0.1 0.31 11.2 0.1 2.1 2 0 0 2 2 2 0 50S ribosome-binding GTPase MCM PF00493.23 CCC67560.1 - 0.077 12.1 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 MCM P-loop domain AIG1 PF04548.16 CCC67560.1 - 0.078 12.3 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 AIG1 family GTP_EFTU PF00009.27 CCC67560.1 - 0.086 12.4 0.1 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Bax1-I PF01027.20 CCC67561.1 - 2.8e-40 138.4 22.6 3.8e-40 137.9 22.6 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Ribosomal_L23 PF00276.20 CCC67562.1 - 6.4e-14 52.1 3.1 4.2e-13 49.5 3.1 1.9 1 1 0 1 1 1 1 Ribosomal protein L23 Ribosomal_S11 PF00411.19 CCC67563.1 - 5.4e-08 33.2 0.0 1.2e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S11 Kri1_C PF12936.7 CCC67564.1 - 2.8e-31 107.5 2.8 2.8e-31 107.5 2.8 5.2 5 1 0 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.12 CCC67564.1 - 4e-16 59.4 17.4 4e-16 59.4 17.4 6.0 4 2 0 6 6 6 1 KRI1-like family CorA PF01544.18 CCC67565.1 - 6.8e-40 137.2 0.7 1.1e-22 80.7 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein zf-DNL PF05180.12 CCC67567.1 - 1.2e-31 108.4 1.5 1.8e-31 107.9 1.5 1.3 1 0 0 1 1 1 1 DNL zinc finger HypA PF01155.19 CCC67567.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-CSL PF05207.13 CCC67567.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 CSL zinc finger zinc_ribbon_4 PF13717.6 CCC67567.1 - 0.3 11.0 4.1 1.3 9.0 4.3 1.9 1 1 0 1 1 1 0 zinc-ribbon domain TFIIS_C PF01096.18 CCC67567.1 - 1.3 8.9 4.5 9.8 6.1 4.7 2.0 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) F-box-like PF12937.7 CCC67568.1 - 7.9e-07 28.9 1.3 1.5e-06 28.0 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CCC67568.1 - 8.7e-06 25.5 0.2 8.7e-06 25.5 0.2 2.4 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 CCC67568.1 - 0.03 14.2 0.4 0.084 12.8 0.4 1.8 1 0 0 1 1 1 0 F-box HMG_box PF00505.19 CCC67569.1 - 4.7e-16 59.0 0.1 1e-15 57.9 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCC67569.1 - 1.8e-12 47.6 0.2 7.4e-12 45.7 0.1 2.1 2 0 0 2 2 2 1 HMG-box domain TFIIA PF03153.13 CCC67569.1 - 0.0024 17.9 15.3 0.0032 17.5 15.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.12 CCC67569.1 - 0.0044 15.3 23.2 0.0067 14.7 23.2 1.4 1 0 0 1 1 1 1 Nop14-like family She9_MDM33 PF05546.11 CCC67569.1 - 0.22 11.3 0.1 0.22 11.3 0.1 2.9 3 0 0 3 3 3 0 She9 / Mdm33 family SAPS PF04499.15 CCC67569.1 - 2 7.1 9.2 2.2 6.9 9.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF155 PF02582.14 CCC67570.1 - 1.2e-56 191.6 0.8 1.9e-56 191.0 0.8 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.6 CCC67570.1 - 0.027 15.0 0.3 0.071 13.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 Histone_H2A_C PF16211.5 CCC67571.1 - 5.5e-21 74.0 1.3 8.9e-21 73.3 1.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CCC67571.1 - 1.2e-17 64.5 0.0 1.7e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCC67571.1 - 7.4e-06 26.2 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LcrG PF07216.12 CCC67571.1 - 0.053 13.5 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 LcrG protein Histone PF00125.24 CCC67572.1 - 1.4e-18 67.5 1.6 1.8e-18 67.1 1.6 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCC67572.1 - 7.8e-06 26.1 0.1 1.4e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CCC67572.1 - 0.0015 19.0 0.0 0.0025 18.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 CCC67572.1 - 0.0092 16.2 0.0 0.014 15.6 0.0 1.2 1 0 0 1 1 1 1 CENP-W protein YscO-like PF16789.5 CCC67572.1 - 0.083 12.9 0.1 0.093 12.8 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein Thiamine_BP PF01910.17 CCC67573.1 - 1.8e-27 95.1 0.0 2.1e-27 94.9 0.0 1.0 1 0 0 1 1 1 1 Thiamine-binding protein AP_endonuc_2 PF01261.24 CCC67573.1 - 0.071 12.5 0.0 0.077 12.4 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Snapin_Pallidin PF14712.6 CCC67573.1 - 0.11 12.9 1.2 1 9.8 0.4 2.1 1 1 1 2 2 2 0 Snapin/Pallidin Med2 PF11214.8 CCC67574.1 - 1.1e-34 118.5 6.1 1.1e-34 118.5 6.1 2.4 2 0 0 2 2 2 1 Mediator complex subunit 2 DUF2229 PF09989.9 CCC67574.1 - 0.16 11.6 2.0 0.29 10.7 2.0 1.4 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) TRH PF05438.12 CCC67574.1 - 0.2 11.4 3.1 0.13 11.9 0.4 1.9 2 0 0 2 2 2 0 Thyrotropin-releasing hormone (TRH) PP2C PF00481.21 CCC67575.1 - 6e-73 245.6 0.1 1.8e-72 244.1 0.1 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CCC67575.1 - 0.0078 16.1 0.2 0.039 13.9 0.2 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) AAA PF00004.29 CCC67576.1 - 1.6e-40 138.6 0.0 2.7e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC67576.1 - 7.5e-10 38.5 0.1 1.4e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CCC67576.1 - 1.5e-09 37.6 0.0 2.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 CCC67576.1 - 6.4e-06 26.5 0.1 0.016 15.5 0.1 2.6 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.13 CCC67576.1 - 1.6e-05 24.2 0.0 2.7e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.14 CCC67576.1 - 2e-05 24.8 0.0 5.9e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCC67576.1 - 0.00016 21.7 0.1 0.00077 19.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCC67576.1 - 0.00019 21.8 0.1 0.007 16.8 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 CCC67576.1 - 0.00079 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CCC67576.1 - 0.004 17.4 0.0 0.008 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 CCC67576.1 - 0.015 15.2 0.1 0.038 13.8 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CCC67576.1 - 0.015 15.4 0.0 0.033 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CCC67576.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCC67576.1 - 0.017 15.7 0.1 0.069 13.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCC67576.1 - 0.018 14.8 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.13 CCC67576.1 - 0.02 14.1 0.0 0.052 12.7 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain NTPase_1 PF03266.15 CCC67576.1 - 0.044 13.7 0.1 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 CCC67576.1 - 0.047 14.1 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 CCC67576.1 - 0.056 12.8 0.1 0.11 11.8 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NB-ARC PF00931.22 CCC67576.1 - 0.058 12.6 0.1 0.6 9.2 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 CCC67576.1 - 0.064 12.8 0.1 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CCC67576.1 - 0.073 12.4 0.0 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 KaiC PhoH PF02562.16 CCC67576.1 - 0.081 12.4 0.4 0.46 9.9 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 CCC67576.1 - 0.1 11.9 0.1 0.18 11.1 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 CCC67576.1 - 0.15 11.8 1.0 0.34 10.6 0.1 2.0 3 0 0 3 3 3 0 AAA domain GalP_UDP_tr_C PF02744.17 CCC67577.1 - 8.3e-69 230.6 0.2 1.9e-68 229.4 0.0 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 CCC67577.1 - 8.8e-68 228.3 0.2 1.3e-67 227.8 0.2 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4921 PF16268.5 CCC67577.1 - 0.0011 17.9 0.2 0.4 9.4 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4921) WG_beta_rep PF14903.6 CCC67577.1 - 0.042 14.1 0.1 0.11 12.8 0.1 1.8 1 0 0 1 1 1 0 WG containing repeat HIT PF01230.23 CCC67577.1 - 0.14 12.9 0.1 0.85 10.4 0.0 2.3 3 0 0 3 3 3 0 HIT domain DUF3721 PF12518.8 CCC67577.1 - 0.38 10.6 1.6 0.9 9.4 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function GalKase_gal_bdg PF10509.9 CCC67578.1 - 1.9e-21 75.3 0.0 3.7e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CCC67578.1 - 2.3e-16 59.8 1.4 2.8e-16 59.5 0.2 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCC67578.1 - 9.4e-13 48.3 0.0 2.4e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal DUF1748 PF08520.10 CCC67578.1 - 0.077 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) Transp_cyt_pur PF02133.15 CCC67579.1 - 3.4e-173 576.5 34.6 4e-173 576.2 34.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ARD PF03079.14 CCC67579.1 - 1.1 9.4 5.3 0.45 10.7 2.9 1.5 2 0 0 2 2 2 0 ARD/ARD' family Macro PF01661.21 CCC67580.1 - 4.4e-26 91.3 0.0 5.2e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Macro domain Chitin_synth_2 PF03142.15 CCC67581.1 - 1.3e-283 941.4 0.1 2.1e-283 940.8 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.6 CCC67581.1 - 9e-10 38.8 6.3 5e-09 36.4 6.3 2.3 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CCC67581.1 - 2.3e-08 34.2 0.0 3e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 CCC67581.1 - 0.00023 20.7 0.0 0.0017 17.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 CCC67581.1 - 0.0037 17.1 0.0 0.052 13.4 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Chitin_synth_1 PF01644.17 CCC67582.1 - 8.4e-71 237.2 0.7 1.5e-70 236.4 0.7 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 CCC67582.1 - 1.3e-21 76.8 7.4 2.2e-18 66.2 0.0 3.1 3 0 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 CCC67582.1 - 2.7e-21 75.3 0.0 7.6e-21 73.9 0.0 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 CCC67582.1 - 6.8e-09 35.9 1.0 6.8e-09 35.9 1.0 2.5 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CCC67582.1 - 3.9e-05 23.7 0.0 9.2e-05 22.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF4222 PF13973.6 CCC67582.1 - 0.2 11.3 1.0 9.3 5.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4222) SCO1-SenC PF02630.14 CCC67583.1 - 6.3e-47 158.9 0.0 1.2e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CCC67583.1 - 1.3e-06 28.3 0.0 1.2e-05 25.3 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA family YchF-GTPase_C PF06071.13 CCC67584.1 - 1.9e-37 127.3 0.1 6.7e-37 125.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CCC67584.1 - 1.2e-16 60.8 0.0 3.2e-16 59.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CCC67584.1 - 0.0012 18.8 0.0 0.0032 17.5 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CCC67584.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B SecA_PP_bind PF01043.20 CCC67584.1 - 0.035 14.8 0.1 0.96 10.1 0.0 2.3 2 0 0 2 2 2 0 SecA preprotein cross-linking domain BetaGal_dom3 PF13363.6 CCC67584.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 YchF-GTPase_C PF06071.13 CCC67585.1 - 4.4e-37 126.1 0.1 1.3e-36 124.6 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CCC67585.1 - 7.6e-17 61.4 0.0 2.1e-16 60.0 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 CCC67585.1 - 0.00059 19.8 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 CCC67585.1 - 0.0094 15.5 0.0 0.019 14.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B ADH_zinc_N PF00107.26 CCC67586.1 - 6.3e-09 35.9 0.0 9.9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF4974 PF16344.5 CCC67586.1 - 0.068 13.2 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) Pkinase PF00069.25 CCC67587.1 - 1e-64 218.5 0.0 1.7e-64 217.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67587.1 - 3e-32 111.9 0.0 1.2e-31 109.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC67587.1 - 0.00044 19.7 0.0 0.0034 16.7 0.0 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 CCC67587.1 - 0.0029 18.3 2.2 0.0092 16.7 2.2 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Pkinase_fungal PF17667.1 CCC67587.1 - 0.14 10.9 0.0 0.26 10.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase CTP_transf_1 PF01148.20 CCC67588.1 - 1.1e-79 267.9 18.9 1.7e-79 267.4 18.9 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DUF433 PF04255.14 CCC67588.1 - 0.052 13.4 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) SET PF00856.28 CCC67589.1 - 6.3e-06 26.7 0.6 0.0081 16.6 0.0 3.3 1 1 2 3 3 3 3 SET domain Ribosomal_L4 PF00573.22 CCC67590.1 - 8.7e-44 149.5 2.1 1.7e-43 148.6 2.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 CCC67590.1 - 2.1e-29 101.4 3.2 2.4e-28 98.0 0.3 2.9 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain Methyltransf_25 PF13649.6 CCC67591.1 - 2.9e-12 47.1 0.0 7.6e-12 45.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.13 CCC67591.1 - 3.5e-11 43.1 0.0 5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CCC67591.1 - 1.1e-10 41.6 0.0 2.3e-10 40.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC67591.1 - 8.2e-09 36.0 0.0 2.4e-08 34.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 CCC67591.1 - 4.5e-08 32.4 0.0 5.6e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 CCC67591.1 - 1.2e-07 31.3 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CCC67591.1 - 1.8e-07 31.2 0.0 3.4e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 CCC67591.1 - 2.3e-05 24.4 0.0 4.6e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC67591.1 - 7.9e-05 23.3 0.0 0.00025 21.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CCC67591.1 - 0.00028 20.5 0.0 0.00047 19.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CCC67591.1 - 0.00065 19.1 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 CCC67591.1 - 0.0015 18.7 0.0 0.0051 17.0 0.0 1.9 2 1 1 3 3 3 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 CCC67591.1 - 0.009 16.0 0.0 0.02 14.9 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 CCC67591.1 - 0.0091 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PCMT PF01135.19 CCC67591.1 - 0.02 14.7 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 CCC67591.1 - 0.02 14.3 0.3 0.066 12.6 0.1 2.0 2 0 0 2 2 2 0 Tellurite resistance protein TehB PRMT5 PF05185.16 CCC67591.1 - 0.025 14.4 0.1 0.049 13.5 0.1 1.4 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase NNMT_PNMT_TEMT PF01234.17 CCC67591.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Cons_hypoth95 PF03602.15 CCC67591.1 - 0.13 11.9 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 CCC67591.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Sld5 PF05916.11 CCC67592.1 - 1.5e-11 44.7 0.2 2.3e-11 44.1 0.2 1.3 1 0 0 1 1 1 1 GINS complex protein Wap1 PF16997.5 CCC67593.1 - 1e-46 159.8 12.7 1e-46 159.8 12.7 1.6 2 0 0 2 2 2 1 Wap1 domain CRCB PF02537.15 CCC67594.1 - 9.8e-30 102.7 15.5 1.1e-17 64.1 6.5 2.4 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) CarS-like PF01864.17 CCC67594.1 - 3.3 7.7 9.0 0.17 11.8 0.4 2.6 3 0 0 3 3 3 0 CDP-archaeol synthase DASH_Dad1 PF08649.10 CCC67596.1 - 1.3e-24 86.1 0.1 2.7e-24 85.1 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Dad1 IPK PF03770.16 CCC67597.1 - 1.9e-49 168.2 2.2 1.9e-49 168.2 0.0 2.1 2 0 0 2 2 2 1 Inositol polyphosphate kinase Acyltransferase PF01553.21 CCC67598.1 - 2.6e-28 98.3 0.0 4e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CCC67598.1 - 6.2e-12 45.4 0.0 1.2e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus GCV_T PF01571.21 CCC67599.1 - 3.6e-80 269.0 0.0 4.4e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 CCC67599.1 - 1.5e-14 53.6 0.0 3.2e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain PRK PF00485.18 CCC67600.1 - 5.2e-09 36.1 0.3 9.5e-07 28.7 0.0 2.1 1 1 1 2 2 2 2 Phosphoribulokinase / Uridine kinase family Cnd3 PF12719.7 CCC67600.1 - 0.025 13.8 0.1 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Spermine_synth PF01564.17 CCC67600.1 - 0.032 13.6 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 Spermine/spermidine synthase domain ApoB100_C PF12491.8 CCC67600.1 - 0.037 14.0 0.2 0.17 11.9 0.0 2.2 2 1 1 3 3 3 0 Apolipoprotein B100 C terminal DEAD PF00270.29 CCC67601.1 - 1.8e-42 145.1 2.1 3.5e-42 144.1 2.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC67601.1 - 7.8e-35 119.6 0.5 9.2e-33 112.9 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC67601.1 - 5.3e-05 23.3 0.0 9.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CCC67601.1 - 0.00061 20.1 0.2 0.0019 18.6 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCC67601.1 - 0.0011 18.8 0.1 0.002 17.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 CCC67601.1 - 0.0031 17.8 0.6 0.013 15.8 0.6 1.9 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.6 CCC67601.1 - 0.011 15.1 0.0 0.028 13.8 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Helicase_RecD PF05127.14 CCC67601.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Helicase Atg31 PF09795.9 CCC67602.1 - 9.6e-55 184.9 11.3 1.1e-54 184.7 11.3 1.0 1 0 0 1 1 1 1 Autophagy-related protein 31 tRNA-synt_2b PF00587.25 CCC67603.1 - 3.9e-33 114.9 0.0 6.9e-33 114.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CCC67603.1 - 1e-21 77.2 9.8 1e-21 77.2 9.8 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain FapA PF03961.13 CCC67603.1 - 0.055 12.1 3.9 0.089 11.4 3.9 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A NOD PF06816.13 CCC67603.1 - 0.073 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 NOTCH protein HDV_ag PF01517.18 CCC67603.1 - 0.35 10.6 2.3 0.69 9.7 2.3 1.4 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Ribosomal_S17_N PF16205.5 CCC67604.1 - 1.7e-31 108.4 0.7 3e-31 107.6 0.7 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CCC67604.1 - 3.4e-27 94.3 4.5 3.4e-27 94.3 4.5 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 DUF922 PF06037.11 CCC67604.1 - 0.086 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) Myb_DNA-binding PF00249.31 CCC67605.1 - 5.4e-22 77.7 10.6 3.9e-12 46.1 0.2 4.2 3 1 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCC67605.1 - 3.4e-14 52.8 0.6 3.4e-14 52.8 0.6 4.9 5 0 0 5 5 5 2 Myb-like DNA-binding domain Rap1_C PF11626.8 CCC67605.1 - 0.089 12.9 0.2 0.089 12.9 0.2 3.8 4 1 0 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Vps54 PF07928.12 CCC67606.1 - 0.00047 20.6 0.0 0.0029 18.0 0.0 2.4 1 1 0 1 1 1 1 Vps54-like protein DUF1752 PF08550.10 CCC67607.1 - 1.5e-12 47.1 3.1 3.4e-12 45.9 3.1 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) WD40 PF00400.32 CCC67608.1 - 2e-16 60.1 7.4 0.0094 16.8 0.7 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC67608.1 - 3.6e-09 36.8 2.0 1.9 8.8 0.0 5.6 2 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain SprB PF13573.6 CCC67608.1 - 0.28 11.0 0.1 0.28 11.0 0.1 3.0 3 0 0 3 3 3 0 SprB repeat FMN_red PF03358.15 CCC67609.1 - 5.3e-11 42.5 0.0 6.8e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CCC67609.1 - 3e-05 23.8 0.0 3.8e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_1 PF00258.25 CCC67609.1 - 0.0079 16.4 0.6 0.077 13.2 0.5 2.3 1 1 0 1 1 1 1 Flavodoxin Dimer_Tnp_hAT PF05699.14 CCC67610.1 - 2.4e-07 30.5 0.2 2e-06 27.5 0.0 2.7 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region HCO3_cotransp PF00955.21 CCC67610.1 - 0.14 10.9 2.6 0.27 10.0 2.6 1.4 1 0 0 1 1 1 0 HCO3- transporter family Mce4_CUP1 PF11887.8 CCC67610.1 - 0.15 11.5 0.9 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Bac_rhodopsin PF01036.18 CCC67611.1 - 1.4e-40 139.2 19.9 1.8e-40 138.9 19.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF3309 PF11752.8 CCC67611.1 - 0.16 12.0 2.5 0.68 10.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) PRP1_N PF06424.12 CCC67612.1 - 9.9e-24 84.4 17.2 3.4e-18 66.5 7.1 2.7 1 1 1 2 2 2 2 PRP1 splicing factor, N-terminal TPR_19 PF14559.6 CCC67612.1 - 1.4e-21 76.8 0.0 0.0065 17.0 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.6 CCC67612.1 - 5.6e-19 67.2 0.0 0.017 15.9 0.0 10.1 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCC67612.1 - 1.7e-12 46.4 4.8 0.016 15.3 0.0 7.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 CCC67612.1 - 2.1e-08 33.6 14.1 0.00093 18.9 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCC67612.1 - 2.5e-08 33.7 2.9 0.085 13.3 0.0 6.7 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCC67612.1 - 1.1e-05 25.6 7.1 3.5 8.0 0.0 7.4 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCC67612.1 - 4.8e-05 23.3 13.5 0.00082 19.4 0.0 7.5 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCC67612.1 - 4.9e-05 23.9 0.0 1.7 9.4 0.0 4.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCC67612.1 - 0.0011 19.5 12.7 4.4 8.2 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCC67612.1 - 0.005 16.5 3.3 5.4 6.8 0.0 5.0 4 1 1 5 5 5 1 TPR repeat TPR_7 PF13176.6 CCC67612.1 - 0.0079 16.2 0.5 6 7.1 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 CCC67612.1 - 0.035 13.7 0.2 10 5.8 0.0 4.1 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) Mad3_BUB1_I PF08311.12 CCC67612.1 - 0.058 13.4 4.5 26 4.8 0.0 5.1 5 0 0 5 5 5 0 Mad3/BUB1 homology region 1 Fungal_trans_2 PF11951.8 CCC67613.1 - 1e-23 83.8 2.4 1.4e-23 83.3 2.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC67613.1 - 1.7e-06 28.0 11.1 3.7e-06 26.9 11.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAHP_synth_1 PF00793.20 CCC67614.1 - 9.2e-106 352.7 0.0 1.1e-105 352.5 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Wtap PF17098.5 CCC67615.1 - 0.0011 18.9 13.8 0.0019 18.2 13.8 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family IKKbetaNEMObind PF12179.8 CCC67615.1 - 0.21 11.7 6.7 0.71 10.0 0.2 3.4 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain FAM76 PF16046.5 CCC67615.1 - 1.5 8.1 10.3 0.37 10.1 0.7 2.1 2 0 0 2 2 2 0 FAM76 protein Takusan PF04822.13 CCC67615.1 - 1.9 8.4 14.8 1.3 8.9 0.8 3.3 2 2 1 3 3 3 0 Takusan ECH_2 PF16113.5 CCC67616.1 - 7.4e-94 315.0 0.1 1e-93 314.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 CCC67616.1 - 2.4e-28 99.1 0.9 7.7e-28 97.5 0.0 1.9 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase RIH_assoc PF08454.11 CCC67616.1 - 0.081 12.8 1.2 1.2 9.0 0.1 2.5 2 0 0 2 2 2 0 RyR and IP3R Homology associated Pkinase PF00069.25 CCC67617.1 - 1.4e-37 129.5 0.1 1.4e-37 129.5 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67617.1 - 9.1e-25 87.4 0.0 2.5e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCC67617.1 - 0.00011 22.3 0.0 0.22 11.4 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family tRNA-synt_2 PF00152.20 CCC67618.1 - 3.6e-74 249.7 0.6 6.8e-74 248.8 0.6 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCC67618.1 - 1.1e-11 44.5 0.1 2.4e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCC67618.1 - 4.6e-07 29.6 0.0 0.0034 16.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DnaJ PF00226.31 CCC67618.1 - 0.084 13.0 2.8 0.19 11.8 0.0 2.7 3 0 0 3 3 3 0 DnaJ domain DUP PF00674.18 CCC67619.1 - 1e-18 67.4 2.2 2.8e-18 66.0 2.2 1.7 1 0 0 1 1 1 1 DUP family E1-E2_ATPase PF00122.20 CCC67620.1 - 1.4e-35 122.4 13.2 2.2e-32 112.0 0.3 3.6 4 0 0 4 4 4 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 CCC67620.1 - 6.9e-27 94.3 2.5 6.9e-27 94.3 2.5 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CCC67620.1 - 4.2e-20 73.0 0.0 6.7e-19 69.0 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCC67620.1 - 1.4e-18 66.7 0.0 2.8e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CCC67620.1 - 4.8e-10 39.0 0.0 1.2e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCC67620.1 - 0.00094 19.0 3.6 0.0016 18.3 1.2 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ribosomal_S10 PF00338.22 CCC67621.1 - 1.6e-32 111.6 0.0 2.6e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf-C2H2 PF00096.26 CCC67623.1 - 0.00012 22.3 1.3 0.00012 22.3 1.3 3.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC67623.1 - 0.013 15.9 5.2 0.013 15.9 5.2 4.1 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC67623.1 - 0.025 15.4 0.8 0.025 15.4 0.8 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3338 PF11819.8 CCC67623.1 - 0.034 14.1 0.1 0.06 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3338) zf-met PF12874.7 CCC67623.1 - 0.059 13.8 0.4 0.059 13.8 0.4 2.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF2895 PF11444.8 CCC67623.1 - 0.12 11.8 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2895) Coprogen_oxidas PF01218.18 CCC67624.1 - 6.4e-136 451.9 0.0 7.3e-136 451.7 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase TFIIS_C PF01096.18 CCC67625.1 - 1.3e-21 76.1 2.2 1.3e-21 76.1 2.2 2.7 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 CCC67625.1 - 3.6e-16 58.7 1.5 1.2e-15 57.0 0.3 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 CCC67625.1 - 0.0022 17.9 4.0 0.34 10.9 0.6 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.12 CCC67625.1 - 0.019 14.9 7.6 0.067 13.2 0.4 3.0 3 0 0 3 3 3 0 PhnA Zinc-Ribbon IBR PF01485.21 CCC67625.1 - 0.3 11.3 8.9 2.2 8.6 0.1 2.7 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-piccolo PF05715.13 CCC67625.1 - 0.54 10.5 6.4 0.54 10.5 0.8 2.8 3 0 0 3 3 3 0 Piccolo Zn-finger AA_permease PF00324.21 CCC67626.1 - 6.1e-136 453.8 31.7 7.7e-136 453.5 31.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC67626.1 - 3.3e-36 125.0 29.5 4.4e-36 124.6 29.5 1.1 1 0 0 1 1 1 1 Amino acid permease URO-D PF01208.17 CCC67627.1 - 5.5e-127 423.7 0.0 6.1e-127 423.5 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) bVLRF1 PF18826.1 CCC67628.1 - 4.8e-57 192.0 0.1 9.5e-57 191.1 0.1 1.5 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor Ank PF00023.30 CCC67628.1 - 0.0088 16.5 0.1 0.027 14.9 0.1 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 CCC67628.1 - 0.013 15.8 0.1 0.097 13.0 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCC67628.1 - 0.057 14.0 0.1 0.28 11.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCC67628.1 - 0.11 13.1 0.0 0.24 12.0 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) HSP20 PF00011.21 CCC67629.1 - 1.4e-22 79.7 2.1 1.9e-22 79.3 2.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CCC67629.1 - 1.7e-06 27.5 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA Pih1_fungal_CS PF18482.1 CCC67629.1 - 0.0071 16.8 2.2 0.009 16.5 0.9 1.9 2 1 0 2 2 2 1 Fungal Pih1 CS domain PIH1_CS PF18201.1 CCC67629.1 - 0.034 14.5 0.1 0.063 13.7 0.1 1.4 1 0 0 1 1 1 0 PIH1 CS-like domain DUF3835 PF12927.7 CCC67629.1 - 0.086 13.7 0.2 1.4 9.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) Alg14 PF08660.11 CCC67631.1 - 1.3e-55 188.0 0.1 1.8e-55 187.6 0.1 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TIM PF00121.18 CCC67632.1 - 3e-89 298.6 0.1 3.4e-89 298.4 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase His_Phos_1 PF00300.22 CCC67633.1 - 4.1e-25 88.6 0.0 6.7e-14 52.0 0.0 3.1 3 0 0 3 3 3 3 Histidine phosphatase superfamily (branch 1) Dfp1_Him1_M PF08630.10 CCC67634.1 - 2.9e-43 147.1 0.2 8.8e-43 145.6 0.2 1.9 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.12 CCC67634.1 - 3.8e-19 68.5 2.0 7e-19 67.7 2.0 1.5 1 0 0 1 1 1 1 DBF zinc finger HHH_8 PF14716.6 CCC67634.1 - 0.047 14.0 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain UQ_con PF00179.26 CCC67635.1 - 1.4e-44 151.1 0.0 1.8e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AMNp_N PF10423.9 CCC67635.1 - 0.023 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus Recep_L_domain PF01030.24 CCC67636.1 - 6.5e-09 35.9 13.3 0.0019 18.3 0.5 5.3 1 1 2 3 3 3 2 Receptor L domain LRR_9 PF14580.6 CCC67636.1 - 0.0047 16.5 0.5 0.012 15.1 0.5 1.7 1 1 0 1 1 1 1 Leucine-rich repeat Ecm33 PF12454.8 CCC67636.1 - 0.59 10.3 7.5 1.3 9.3 2.8 3.1 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein Yos9_DD PF17880.1 CCC67637.1 - 4.9e-44 149.5 0.2 1.9e-43 147.6 0.0 2.2 2 0 0 2 2 2 1 Yos9 dimerzation domain PRKCSH PF07915.13 CCC67637.1 - 1.8e-08 35.2 0.7 1.8e-08 35.2 0.7 3.7 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein UQ_con PF00179.26 CCC67638.1 - 5.3e-52 175.2 0.0 5.9e-52 175.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCC67638.1 - 0.0011 19.3 0.0 0.0015 18.8 0.0 1.3 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 CCC67638.1 - 0.0031 17.2 0.0 0.0038 16.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 CCC67638.1 - 0.0098 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 UEV domain Gp_dh_C PF02800.20 CCC67639.1 - 4.3e-72 240.9 0.1 7.6e-72 240.1 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CCC67639.1 - 3e-40 136.6 0.3 7.7e-40 135.3 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CCC67639.1 - 0.0095 16.1 0.3 0.037 14.2 0.3 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TEA PF01285.18 CCC67640.1 - 8.1e-25 86.7 0.5 1.8e-24 85.6 0.5 1.6 1 0 0 1 1 1 1 TEA/ATTS domain MCM6_C PF18263.1 CCC67640.1 - 0.011 16.0 0.6 0.022 15.0 0.6 1.5 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain Arm-DNA-bind_5 PF17293.2 CCC67640.1 - 0.094 13.2 0.1 0.094 13.2 0.1 2.0 2 0 0 2 2 2 0 Arm DNA-binding domain KIP1 PF07765.12 CCC67640.1 - 0.16 12.1 1.0 0.97 9.6 0.5 2.2 2 0 0 2 2 2 0 KIP1-like protein Ribosomal_L19e PF01280.20 CCC67641.1 - 6e-58 195.0 8.7 6e-58 195.0 8.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e DUF2423 PF10338.9 CCC67642.1 - 7.5e-19 67.7 3.2 7.5e-19 67.7 3.2 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) DUF4632 PF15451.6 CCC67642.1 - 0.076 13.1 0.4 0.12 12.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) Drc1-Sld2 PF11719.8 CCC67642.1 - 0.57 9.7 10.8 0.65 9.5 10.8 1.0 1 0 0 1 1 1 0 DNA replication and checkpoint protein Dimer_Tnp_hAT PF05699.14 CCC67644.1 - 8.1e-09 35.2 0.1 2.8e-08 33.4 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CCC67644.1 - 0.18 11.9 0.5 0.47 10.5 0.5 1.8 1 0 0 1 1 1 0 BED zinc finger Rep_1 PF01446.17 CCC67645.1 - 0.00055 19.5 0.1 0.00075 19.0 0.1 1.2 1 0 0 1 1 1 1 Replication protein zinc_ribbon_15 PF17032.5 CCC67645.1 - 0.0025 18.6 0.3 0.0033 18.1 0.3 1.3 1 0 0 1 1 1 1 zinc-ribbon family Zn_Tnp_IS1595 PF12760.7 CCC67645.1 - 0.013 15.4 5.2 0.24 11.4 0.4 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 CCC67645.1 - 0.026 13.9 3.5 2.4 7.7 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-TFIIB PF13453.6 CCC67645.1 - 0.058 12.7 0.8 1.1 8.6 0.0 2.3 2 1 0 2 2 2 0 Transcription factor zinc-finger TF_Zn_Ribbon PF08271.12 CCC67645.1 - 0.061 12.9 0.8 1.6 8.3 0.2 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_Tnp_IS1 PF03811.13 CCC67645.1 - 0.075 12.8 1.7 2.9 7.7 0.3 2.2 2 0 0 2 2 2 0 InsA N-terminal domain RecR PF02132.15 CCC67645.1 - 0.14 11.8 3.9 1.1 8.9 3.9 2.1 1 1 0 1 1 1 0 RecR protein Auto_anti-p27 PF06677.12 CCC67645.1 - 0.24 11.6 1.0 8.4 6.6 0.1 2.2 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Mito_carr PF00153.27 CCC67646.1 - 9.9e-67 220.9 7.6 2.2e-23 82.0 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Msap1 PF17077.5 CCC67647.1 - 1.5e-22 80.3 31.3 2e-22 79.8 31.3 1.2 1 0 0 1 1 1 1 Mitotic spindle associated protein SHE1 KH_1 PF00013.29 CCC67648.1 - 2.1e-34 117.2 8.2 1.6e-13 50.2 0.2 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 CCC67648.1 - 1.5e-05 24.7 1.0 1.3 9.0 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CCC67648.1 - 5.9e-05 22.8 10.3 0.19 11.6 0.1 3.7 3 1 0 3 3 3 3 KH domain KH_5 PF13184.6 CCC67648.1 - 0.0036 17.3 9.0 2.4 8.3 0.2 3.7 3 1 1 4 4 4 3 NusA-like KH domain CENP-B_dimeris PF09026.10 CCC67648.1 - 0.27 11.6 4.4 0.33 11.4 0.0 2.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain GTP_cyclohydro2 PF00925.20 CCC67649.1 - 8.3e-56 188.1 0.0 1.2e-55 187.5 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II CLASP_N PF12348.8 CCC67650.1 - 1.4e-66 224.3 28.4 2e-63 214.0 10.1 4.5 4 1 0 4 4 4 2 CLASP N terminal Pol_alpha_B_N PF08418.10 CCC67651.1 - 8e-68 229.0 11.8 1.1e-67 228.6 11.8 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.16 CCC67651.1 - 8.6e-47 159.2 0.3 1.5e-46 158.4 0.3 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CDC48_N PF02359.18 CCC67651.1 - 0.064 13.4 0.1 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain DNA_pol_D_N PF18018.1 CCC67651.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.7 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain Anoctamin PF04547.12 CCC67652.1 - 1.1e-24 87.1 28.3 3.7e-24 85.4 28.3 1.8 1 1 0 1 1 1 1 Calcium-activated chloride channel Adaptin_N PF01602.20 CCC67653.1 - 2.7e-109 366.1 24.6 3.3e-109 365.8 24.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 CCC67653.1 - 2.9e-05 24.2 0.2 0.00012 22.2 0.2 2.2 1 1 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT PF02985.22 CCC67653.1 - 0.019 15.2 0.3 0.51 10.7 0.1 3.4 3 0 0 3 3 3 0 HEAT repeat Alpha_adaptinC2 PF02883.20 CCC67653.1 - 0.1 12.9 0.1 0.1 12.9 0.1 2.4 2 0 0 2 2 2 0 Adaptin C-terminal domain DUF5082 PF16888.5 CCC67653.1 - 0.1 12.8 2.2 0.25 11.6 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) DNA_pol3_delta2 PF13177.6 CCC67654.1 - 1.1e-10 41.5 0.2 1.7e-09 37.7 0.2 2.2 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 CCC67654.1 - 1.2e-06 28.9 0.0 2.9e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CCC67654.1 - 0.00037 20.8 0.6 0.0018 18.7 0.1 2.4 3 0 0 3 3 3 1 Replication factor C C-terminal domain Rad17 PF03215.15 CCC67654.1 - 0.0032 17.4 0.0 0.0056 16.6 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain Orbi_VP2 PF00898.17 CCC67654.1 - 0.0063 14.3 0.2 0.008 14.0 0.2 1.1 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP2 AAA_assoc_2 PF16193.5 CCC67654.1 - 0.0064 16.8 0.1 0.038 14.3 0.0 2.1 2 0 0 2 2 2 1 AAA C-terminal domain DNA_pol3_delta PF06144.13 CCC67654.1 - 0.0071 16.1 0.2 0.11 12.3 0.2 2.3 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 CCC67654.1 - 0.016 15.6 0.0 0.041 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MobC PF05713.11 CCC67654.1 - 0.041 14.3 1.4 0.58 10.7 0.1 2.7 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) NYD-SP12_N PF15015.6 CCC67654.1 - 0.061 11.7 0.1 0.089 11.1 0.1 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Ribosomal_L16 PF00252.18 CCC67655.1 - 3.1e-36 124.3 0.1 4.6e-36 123.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e tRNA-synt_2d PF01409.20 CCC67656.1 - 3.4e-48 164.3 0.5 5.4e-26 91.6 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 CCC67656.1 - 1.4e-25 89.5 0.2 8.8e-25 87.0 0.0 2.2 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain HisK_N PF09385.10 CCC67656.1 - 0.03 14.3 2.4 0.1 12.6 0.2 2.5 2 0 0 2 2 2 0 Histidine kinase N terminal tRNA-synt_2 PF00152.20 CCC67656.1 - 1.1 8.3 4.2 7.3 5.6 0.0 2.9 2 1 0 3 3 3 0 tRNA synthetases class II (D, K and N) ATG11 PF10377.9 CCC67657.1 - 2.2e-38 131.2 0.1 2.2e-38 131.2 0.1 2.7 2 0 0 2 2 2 1 Autophagy-related protein 11 SAM_Exu PF18609.1 CCC67657.1 - 0.51 10.5 3.7 1.5 8.9 0.0 3.7 4 0 0 4 4 4 0 Exuperantia SAM-like domain Aconitase_C PF00694.19 CCC67657.1 - 4.5 7.6 6.5 1.6 9.0 1.8 2.8 2 1 0 2 2 2 0 Aconitase C-terminal domain Acetyltransf_1 PF00583.25 CCC67658.1 - 8.9e-17 61.4 0.0 1.1e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCC67658.1 - 7.3e-12 45.3 0.0 1e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCC67658.1 - 9.9e-12 45.1 0.0 1.3e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCC67658.1 - 4.5e-08 32.9 0.1 6.7e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 CCC67658.1 - 6.1e-05 22.7 0.0 8.6e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CCC67658.1 - 0.0002 21.5 0.0 0.00044 20.3 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CCC67658.1 - 0.00021 22.0 0.0 0.00024 21.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CCC67658.1 - 0.0018 18.4 0.0 0.0034 17.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.6 CCC67658.1 - 0.016 15.2 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Acetyltransf_15 PF17013.5 CCC67658.1 - 0.017 14.6 0.1 0.039 13.4 0.1 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase HMG_box PF00505.19 CCC67659.1 - 3.2e-25 88.3 2.0 5.3e-25 87.6 2.0 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCC67659.1 - 6.5e-19 68.3 1.7 1.1e-18 67.6 1.7 1.4 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 CCC67659.1 - 0.00075 20.0 0.0 0.00075 20.0 0.0 2.1 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 CHDNT PF08073.12 CCC67659.1 - 0.0043 17.0 0.0 0.0065 16.4 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain YABBY PF04690.13 CCC67659.1 - 0.061 13.9 0.8 0.061 13.9 0.8 1.7 1 1 1 2 2 2 0 YABBY protein Pkinase PF00069.25 CCC67660.1 - 1.1e-61 208.6 0.0 1.3e-61 208.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67660.1 - 9.3e-30 103.8 0.0 1.4e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCC67660.1 - 2.8e-05 23.2 0.1 4.2e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 CCC67660.1 - 0.016 14.3 0.1 0.032 13.3 0.1 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Sec8_exocyst PF04048.14 CCC67661.1 - 1.2e-48 164.6 4.5 6.8e-48 162.2 4.5 2.4 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Sec5 PF15469.6 CCC67661.1 - 6.2e-07 29.4 14.5 6.2e-07 29.4 14.5 2.8 2 1 0 2 2 2 1 Exocyst complex component Sec5 Phage_term_sma PF07141.11 CCC67661.1 - 0.05 13.4 1.5 0.13 12.0 0.4 2.2 2 0 0 2 2 2 0 Putative bacteriophage terminase small subunit Exonuc_VII_L PF02601.15 CCC67661.1 - 0.91 9.0 12.5 0.14 11.7 7.8 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tfb4 PF03850.14 CCC67662.1 - 2e-106 355.5 0.2 2.3e-106 355.3 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 Rad50_zn_hook PF04423.14 CCC67662.1 - 0.013 15.3 0.2 0.071 13.0 0.2 2.2 1 0 0 1 1 1 0 Rad50 zinc hook motif Cucumopine_C PF18631.1 CCC67662.1 - 0.097 12.6 0.2 23 4.9 0.1 3.0 3 0 0 3 3 3 0 Cucumopine synthase C-terminal helical bundle domain SIP1 PF04938.12 CCC67663.1 - 6e-07 29.4 3.4 1.1e-05 25.3 3.4 2.2 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Mito_carr PF00153.27 CCC67664.1 - 1.1e-60 201.6 1.6 5.5e-21 74.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CM_2 PF01817.21 CCC67665.1 - 8.2e-05 22.9 0.0 0.016 15.5 0.1 2.6 2 1 0 2 2 2 2 Chorismate mutase type II DnaJ PF00226.31 CCC67666.1 - 3.8e-07 30.1 4.0 3e-06 27.3 4.0 2.3 1 1 0 1 1 1 1 DnaJ domain dCMP_cyt_deam_1 PF00383.23 CCC67667.1 - 6.7e-21 74.1 0.0 8.6e-21 73.7 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCC67667.1 - 3.3e-19 69.0 0.0 4.3e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 CCC67667.1 - 0.00039 20.5 0.0 0.00078 19.6 0.0 1.5 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 CCC67667.1 - 0.0005 20.2 0.1 0.00093 19.3 0.1 1.5 1 1 0 1 1 1 1 Bd3614-like deaminase NAD1 PF18778.1 CCC67667.1 - 0.00074 19.6 0.0 0.036 14.2 0.0 2.0 2 0 0 2 2 2 1 Novel AID APOBEC clade 1 APOBEC2 PF18772.1 CCC67667.1 - 0.0054 16.8 0.0 0.065 13.3 0.0 1.9 2 0 0 2 2 2 1 APOBEC2 NAD2 PF18782.1 CCC67667.1 - 0.066 13.3 0.0 0.28 11.3 0.0 1.8 2 0 0 2 2 2 0 Novel AID APOBEC clade 2 Inv-AAD PF18785.1 CCC67667.1 - 0.18 11.7 0.3 0.57 10.1 0.3 2.0 1 1 0 1 1 1 0 Invertebrate-AID/APOBEC-deaminase UPF0139 PF03669.13 CCC67668.1 - 0.00061 19.6 0.7 0.0011 18.7 0.7 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0139) Methyltransf_17 PF12692.7 CCC67668.1 - 0.071 13.1 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase Vac_ImportDeg PF09783.9 CCC67669.1 - 1.3e-43 148.7 0.0 1.7e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein HMG_box PF00505.19 CCC67670.1 - 5.9e-17 61.9 2.1 5.9e-17 61.9 2.1 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCC67670.1 - 2.3e-08 34.5 0.4 2.3e-08 34.5 0.4 2.0 2 0 0 2 2 2 1 HMG-box domain Pho88 PF10032.9 CCC67671.1 - 3.4e-78 261.1 0.4 3.8e-78 260.9 0.4 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) DUF4512 PF14975.6 CCC67671.1 - 0.087 13.6 0.1 0.19 12.5 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4512) ThiF PF00899.21 CCC67672.1 - 2.8e-51 174.3 0.1 3.5e-51 173.9 0.1 1.2 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.20 CCC67672.1 - 0.0027 17.8 0.0 0.0049 16.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.27 CCC67672.1 - 0.015 15.9 0.0 0.024 15.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Tubulin_2 PF13809.6 CCC67672.1 - 0.091 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Tubulin like DUF5058 PF16481.5 CCC67672.1 - 0.097 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5058) DUF2857 PF11198.8 CCC67672.1 - 0.19 11.5 0.1 0.75 9.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) Fe-S_biosyn PF01521.20 CCC67673.1 - 4.8e-13 49.3 0.1 3.3e-10 40.1 0.1 2.2 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis GIDE PF12483.8 CCC67673.1 - 0.1 12.0 0.0 1.2 8.5 0.0 2.1 2 0 0 2 2 2 0 E3 Ubiquitin ligase AIM3 PF17096.5 CCC67674.1 - 4.4e-21 75.6 7.7 4.4e-21 75.6 7.7 6.4 5 3 1 6 6 6 2 Altered inheritance of mitochondria protein 3 Erp_C PF06780.11 CCC67674.1 - 0.038 14.0 0.4 0.075 13.0 0.4 1.4 1 0 0 1 1 1 0 Erp protein C-terminus EF-hand_1 PF00036.32 CCC67675.1 - 2.1e-29 98.9 8.9 2.5e-08 32.9 0.1 4.6 4 1 1 5 5 5 4 EF hand EF-hand_7 PF13499.6 CCC67675.1 - 9.6e-28 96.4 2.3 3.5e-15 56.2 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCC67675.1 - 5.7e-25 85.1 7.6 1.9e-08 33.6 0.0 4.6 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.6 CCC67675.1 - 1e-17 62.7 12.3 6e-08 31.8 0.1 5.0 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 CCC67675.1 - 1.1e-16 60.4 7.9 5.1e-09 35.8 0.1 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CCC67675.1 - 3.5e-13 49.7 0.1 7.4e-10 39.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 CCC67675.1 - 2.3e-07 31.1 0.4 0.014 15.7 0.1 2.3 1 1 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CCC67675.1 - 5e-07 30.0 0.2 0.0019 18.5 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CCC67675.1 - 0.0019 18.4 1.1 0.41 10.9 0.3 2.9 2 1 0 2 2 2 1 Dockerin type I domain SurA_N_3 PF13624.6 CCC67675.1 - 0.0028 17.4 1.2 0.044 13.6 1.3 2.0 1 1 1 2 2 2 1 SurA N-terminal domain EF-hand_4 PF12763.7 CCC67675.1 - 0.0042 17.0 0.5 0.015 15.3 0.1 1.8 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CCC67675.1 - 0.0076 16.2 0.1 3.6 7.5 0.0 2.8 1 1 2 3 3 3 1 Caleosin related protein UPF0154 PF03672.13 CCC67675.1 - 0.0089 16.0 0.0 0.37 10.8 0.0 2.8 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) TerB PF05099.13 CCC67675.1 - 0.01 15.8 0.2 0.17 11.9 0.1 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF853 PF05872.12 CCC67675.1 - 0.037 12.6 0.2 0.071 11.7 0.2 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) RNA_pol_Rpb4 PF03874.16 CCC67675.1 - 0.27 11.5 3.1 3.1 8.2 1.4 2.5 1 1 1 2 2 2 0 RNA polymerase Rpb4 Hist_deacetyl PF00850.19 CCC67676.1 - 2.2e-75 254.0 0.0 2.9e-75 253.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Med1 PF10744.9 CCC67677.1 - 1.6e-26 93.3 6.3 6.4e-26 91.4 0.8 3.2 2 1 1 3 3 3 2 Mediator of RNA polymerase II transcription subunit 1 CAF20 PF17052.5 CCC67677.1 - 0.045 13.9 2.2 0.099 12.8 2.2 1.6 1 0 0 1 1 1 0 Cap associated factor TPR_1 PF00515.28 CCC67678.1 - 9.8e-52 170.8 19.9 2.2e-07 30.4 0.0 10.9 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 CCC67678.1 - 3.2e-45 148.6 22.3 0.00012 21.9 0.0 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.6 CCC67678.1 - 6.5e-33 110.7 21.8 2.3e-05 24.4 0.1 11.5 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 CCC67678.1 - 8.3e-30 100.5 17.7 0.011 15.9 0.0 11.0 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_14 PF13428.6 CCC67678.1 - 3e-24 83.6 18.9 0.0013 19.3 0.2 10.2 4 3 6 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 CCC67678.1 - 1.2e-22 79.2 21.9 4.5e-05 23.0 0.0 9.7 4 2 6 10 10 10 6 TPR repeat TPR_16 PF13432.6 CCC67678.1 - 2.3e-22 79.3 12.8 0.00069 20.2 1.7 7.0 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 CCC67678.1 - 3.1e-22 78.8 13.1 9e-05 22.9 0.3 8.0 4 3 2 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 CCC67678.1 - 6.9e-19 67.8 13.9 0.0012 18.9 0.0 6.6 3 1 4 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 CCC67678.1 - 8.4e-19 67.6 27.4 0.00044 20.5 0.3 8.1 3 2 3 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 CCC67678.1 - 7.4e-18 63.2 21.8 0.00049 19.9 0.3 9.4 8 1 1 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 CCC67678.1 - 6.6e-14 51.5 14.9 0.25 12.1 0.0 9.8 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC67678.1 - 4.7e-12 46.0 9.8 0.00032 20.9 1.7 3.8 4 0 0 4 4 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CCC67678.1 - 2e-06 27.4 16.1 0.1 12.5 0.4 7.7 8 0 0 8 8 8 3 Tetratricopeptide repeat SDH_alpha PF03313.15 CCC67678.1 - 1.7 8.3 4.4 0.51 10.0 1.2 1.8 2 0 0 2 2 2 0 Serine dehydratase alpha chain Not3 PF04065.15 CCC67679.1 - 3.6e-63 213.1 35.5 2.9e-50 170.8 22.8 3.5 2 2 1 3 3 3 2 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CCC67679.1 - 6.6e-38 129.8 3.3 6.6e-38 129.8 3.3 3.4 3 1 0 4 4 4 1 NOT2 / NOT3 / NOT5 family Lip_prot_lig_C PF10437.9 CCC67679.1 - 0.27 11.2 6.1 2.3 8.2 0.4 4.1 5 0 0 5 5 5 0 Bacterial lipoate protein ligase C-terminus Imm6 PF14434.6 CCC67679.1 - 0.4 10.6 7.8 1.2 9.1 1.3 2.9 1 1 1 2 2 2 0 Immunity protein Imm6 Zip PF02535.22 CCC67679.1 - 0.84 8.8 2.5 1.6 7.8 2.5 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Plasmid_RAQPRD PF09686.10 CCC67679.1 - 1.2 9.4 7.4 0.47 10.7 1.3 3.3 4 1 0 4 4 4 0 Plasmid protein of unknown function (Plasmid_RAQPRD) LMWPc PF01451.21 CCC67680.1 - 5.8e-45 153.2 0.0 6.6e-45 153.0 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Transketolase_N PF00456.21 CCC67681.1 - 2.2e-160 533.1 0.0 6.3e-160 531.6 0.0 1.6 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CCC67681.1 - 5.1e-49 166.4 0.0 8.5e-49 165.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CCC67681.1 - 6e-15 55.2 0.0 1.5e-14 53.9 0.0 1.8 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 CCC67681.1 - 8.6e-05 21.6 0.1 0.0004 19.4 0.0 1.9 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CCC67681.1 - 0.0057 15.9 0.0 0.01 15.1 0.0 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Opy2 PF09463.10 CCC67682.1 - 5.8e-09 36.1 19.9 8.7e-09 35.6 19.9 1.3 1 0 0 1 1 1 1 Opy2 protein Amnionless PF14828.6 CCC67682.1 - 0.0028 16.5 0.0 0.0028 16.5 0.0 1.6 1 1 1 2 2 2 1 Amnionless BNIP2 PF12496.8 CCC67682.1 - 0.03 14.8 0.1 0.03 14.8 0.1 2.6 2 1 0 2 2 2 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Phage_holin_2_4 PF16082.5 CCC67682.1 - 0.087 12.6 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like YL1 PF05764.13 CCC67682.1 - 2 8.5 14.8 3.9 7.5 14.7 1.6 1 1 0 1 1 1 0 YL1 nuclear protein GTP_EFTU PF00009.27 CCC67684.1 - 1e-54 185.0 0.0 1.5e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCC67684.1 - 3.4e-40 136.8 0.0 7.2e-40 135.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCC67684.1 - 6.4e-15 55.3 3.8 7.3e-15 55.1 1.7 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCC67684.1 - 0.00029 20.9 0.1 0.0067 16.5 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CCC67684.1 - 0.045 13.6 0.9 0.045 13.6 0.9 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 DIM1 PF02966.16 CCC67685.1 - 7.1e-68 226.5 0.5 8e-68 226.3 0.5 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 CCC67685.1 - 0.00017 21.5 0.0 0.00023 21.1 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF3192 PF11399.8 CCC67685.1 - 0.012 15.5 0.1 0.019 14.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Glyco_transf_20 PF00982.21 CCC67686.1 - 3e-202 672.5 0.0 3.4e-202 672.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 CCC67686.1 - 0.00014 21.4 0.7 0.013 15.0 0.1 3.0 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCC67686.1 - 0.0017 18.8 0.1 0.0068 16.8 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CCC67686.1 - 0.077 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 zf-RING_9 PF13901.6 CCC67687.1 - 1.1 9.2 6.2 0.62 10.0 0.3 2.5 1 1 0 2 2 2 0 Putative zinc-RING and/or ribbon Ras PF00071.22 CCC67688.1 - 0.00014 21.5 0.0 0.66 9.6 0.0 2.7 3 0 0 3 3 3 2 Ras family AAA_28 PF13521.6 CCC67688.1 - 0.0095 16.2 0.0 0.017 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Roc PF08477.13 CCC67688.1 - 0.08 13.2 0.1 0.57 10.4 0.0 2.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase SHE3 PF17078.5 CCC67690.1 - 5.6e-46 157.1 32.8 5.6e-46 157.1 32.8 2.0 2 0 0 2 2 2 1 SWI5-dependent HO expression protein 3 CENP-H PF05837.12 CCC67690.1 - 0.027 14.9 34.3 0.79 10.2 5.8 4.2 2 1 2 4 4 4 0 Centromere protein H (CENP-H) Bcl-2_BAD PF10514.9 CCC67690.1 - 0.11 12.9 1.8 0.67 10.4 1.8 2.3 1 1 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD UCH_C PF18031.1 CCC67690.1 - 0.61 10.0 5.5 2.5 8.1 0.3 3.3 3 0 0 3 3 3 0 Ubiquitin carboxyl-terminal hydrolases FlaC_arch PF05377.11 CCC67690.1 - 0.99 9.9 13.0 1.7 9.1 0.2 4.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) HalX PF08663.10 CCC67690.1 - 1.7 9.0 9.5 11 6.4 3.2 3.0 2 1 0 2 2 2 0 HalX domain DIL PF01843.19 CCC67691.1 - 3.1e-16 59.5 8.3 3.3e-09 37.0 0.2 3.6 3 0 0 3 3 3 2 DIL domain Ank_2 PF12796.7 CCC67691.1 - 1.6e-05 25.4 0.1 4.2e-05 24.1 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCC67691.1 - 0.0015 19.1 1.5 0.039 14.5 0.6 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CCC67691.1 - 0.096 13.0 0.6 23 5.5 0.3 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) MMM1 PF10296.9 CCC67692.1 - 5.5e-10 38.8 2.1 5.5e-10 38.8 2.1 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 PH_11 PF15413.6 CCC67692.1 - 1.3e-07 32.0 0.3 1.3e-07 32.0 0.3 2.4 2 1 1 3 3 3 1 Pleckstrin homology domain PH PF00169.29 CCC67692.1 - 1.8e-05 25.2 2.1 7.2e-05 23.2 1.6 2.5 2 1 0 2 2 2 1 PH domain zf-RING_2 PF13639.6 CCC67693.1 - 2.5e-14 53.3 19.9 1.3e-11 44.6 5.2 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.25 CCC67693.1 - 1e-08 34.9 3.8 1e-08 34.9 3.8 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCC67693.1 - 2.3e-08 33.7 4.6 2.3e-08 33.7 4.6 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CCC67693.1 - 7e-07 29.4 17.5 2.7e-06 27.6 6.1 3.0 2 2 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CCC67693.1 - 2e-05 24.3 1.2 2e-05 24.3 1.2 2.7 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 CCC67693.1 - 0.00033 20.6 3.9 0.00033 20.6 3.9 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CCC67693.1 - 0.00045 20.0 5.0 0.00045 20.0 5.0 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 CCC67693.1 - 0.00097 19.0 1.7 0.00097 19.0 1.7 2.9 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.6 CCC67693.1 - 0.005 16.8 6.4 0.005 16.8 6.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 CCC67693.1 - 0.0057 16.6 8.1 0.0057 16.6 8.1 2.9 3 0 0 3 3 2 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CCC67693.1 - 0.014 15.0 18.5 0.067 12.8 4.0 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 CCC67693.1 - 0.022 14.7 6.9 0.022 14.7 6.9 2.9 2 1 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 CCC67693.1 - 0.029 14.3 2.6 0.029 14.3 2.6 3.9 3 1 1 4 4 4 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 CCC67693.1 - 0.084 13.0 12.6 0.79 9.9 2.8 2.6 2 0 0 2 2 2 0 KIAA1045 RING finger YoeB_toxin PF06769.14 CCC67693.1 - 0.095 12.7 0.5 6.5 6.9 0.2 2.5 2 0 0 2 2 2 0 YoeB-like toxin of bacterial type II toxin-antitoxin system zf-RING-like PF08746.11 CCC67693.1 - 0.13 12.6 17.6 0.78 10.1 2.7 2.8 2 0 0 2 2 2 0 RING-like domain zf-ribbon_3 PF13248.6 CCC67693.1 - 0.16 11.4 5.4 3.6 7.1 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-HC5HC2H PF13771.6 CCC67693.1 - 0.93 9.8 11.5 3.4 8.0 2.4 2.8 2 0 0 2 2 2 0 PHD-like zinc-binding domain Rad50_zn_hook PF04423.14 CCC67693.1 - 1.3 9.0 6.3 40 4.1 0.0 4.2 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-C3HC4_4 PF15227.6 CCC67693.1 - 1.6 9.0 11.7 0.53 10.5 2.6 3.4 2 2 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 CCC67693.1 - 2.4 8.0 10.2 3.9 7.4 2.3 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.8 CCC67693.1 - 3.5 7.9 19.3 3.5 7.9 5.4 3.0 2 2 0 2 2 2 0 FANCL C-terminal domain PHF5 PF03660.14 CCC67694.1 - 2.3e-50 169.2 13.9 2.5e-50 169.0 13.9 1.0 1 0 0 1 1 1 1 PHF5-like protein Sec7 PF01369.20 CCC67695.1 - 3.3e-24 85.6 3.1 3.3e-24 85.6 3.1 2.5 3 0 0 3 3 3 1 Sec7 domain DUF3818 PF12825.7 CCC67696.1 - 5.4e-127 423.5 11.7 5.4e-127 423.5 11.7 2.7 4 0 0 4 4 4 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.7 CCC67696.1 - 9.9e-43 145.2 3.0 9.9e-43 145.2 3.0 2.2 2 0 0 2 2 2 1 PX-associated PX PF00787.24 CCC67696.1 - 3.1e-09 36.8 4.4 3.1e-09 36.8 4.4 3.1 2 1 0 2 2 2 1 PX domain Glyco_hydro_25 PF01183.20 CCC67696.1 - 0.11 12.6 2.1 0.21 11.8 0.2 2.4 3 0 0 3 3 3 0 Glycosyl hydrolases family 25 MAS20 PF02064.15 CCC67697.1 - 5.5e-36 123.5 0.2 5.5e-36 123.5 0.2 2.1 2 0 0 2 2 2 1 MAS20 protein import receptor GOLD_2 PF13897.6 CCC67697.1 - 0.65 10.5 0.0 0.65 10.5 0.0 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking TERB2 PF15101.6 CCC67697.1 - 0.99 9.4 3.9 9 6.3 1.0 2.1 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF4149 PF13664.6 CCC67698.1 - 5.2e-21 74.9 2.1 1.2e-20 73.7 0.9 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Oleosin PF01277.17 CCC67698.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Oleosin L51_S25_CI-B8 PF05047.16 CCC67699.1 - 1.1e-12 47.6 0.3 1.9e-12 46.9 0.3 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain BCAS2 PF05700.11 CCC67700.1 - 4e-08 33.2 13.7 5.4e-07 29.5 13.7 2.3 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF4404 PF14357.6 CCC67700.1 - 0.33 11.6 3.5 5.9 7.6 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Binary_toxB_3 PF17476.2 CCC67700.1 - 0.59 10.3 8.1 0.54 10.5 0.8 2.4 2 0 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA domain 3 Ribosomal_L5_C PF00673.21 CCC67701.1 - 2.5e-22 78.9 0.0 3.9e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CCC67701.1 - 1.6e-19 70.0 0.1 4.9e-19 68.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 CCC67701.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Fission yeast centromere protein N-terminal domain Proteasome PF00227.26 CCC67702.1 - 1.3e-47 161.8 0.1 1.6e-47 161.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Forkhead PF00250.18 CCC67703.1 - 1.8e-25 89.0 1.1 1.8e-24 85.8 0.0 2.5 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 CCC67703.1 - 3.3e-13 49.8 0.2 8e-13 48.5 0.2 1.7 1 0 0 1 1 1 1 FHA domain COG4 PF08318.12 CCC67704.1 - 2e-87 293.4 8.9 3.5e-87 292.6 8.9 1.4 1 0 0 1 1 1 1 COG4 transport protein Pil1 PF13805.6 CCC67705.1 - 8.3e-116 386.1 0.2 9.8e-116 385.9 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Arm-DNA-bind_1 PF09003.10 CCC67705.1 - 0.058 13.5 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 Bacteriophage lambda integrase, Arm DNA-binding domain zf-CCCH PF00642.24 CCC67706.1 - 8e-17 60.7 28.1 2e-05 24.4 0.6 5.6 4 2 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCC67706.1 - 1.2e-14 53.8 29.1 4.8e-06 26.5 2.4 5.3 5 0 0 5 5 5 3 Zinc finger domain Torus PF16131.5 CCC67706.1 - 9.2e-11 42.4 20.4 0.00056 20.6 0.5 5.1 1 1 4 5 5 5 4 Torus domain zf-CCCH_3 PF15663.5 CCC67706.1 - 2.9e-07 30.7 14.0 4.2e-07 30.2 5.9 2.6 1 1 1 2 2 2 2 Zinc-finger containing family zf-CCCH_4 PF18044.1 CCC67706.1 - 0.016 15.0 1.2 0.016 15.0 1.2 4.6 4 1 0 4 4 4 0 CCCH-type zinc finger RPN7 PF10602.9 CCC67707.1 - 9.2e-50 168.7 3.3 9.2e-50 168.7 3.3 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.27 CCC67707.1 - 7e-16 58.6 0.1 2.2e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 PCI domain Interferon PF00143.19 CCC67707.1 - 0.063 13.5 0.2 0.14 12.3 0.2 1.6 1 0 0 1 1 1 0 Interferon alpha/beta domain MFS_1 PF07690.16 CCC67708.1 - 6e-10 38.6 40.0 3.5e-08 32.8 37.8 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC67708.1 - 7.7e-06 25.0 9.6 7.7e-06 25.0 9.6 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter OppC_N PF12911.7 CCC67708.1 - 8.4 6.5 7.7 32 4.6 0.1 3.6 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DUF1746 PF08508.10 CCC67709.1 - 6.1e-05 23.3 3.2 0.81 10.1 2.3 3.0 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1746) RNA_pol_A_bac PF01000.26 CCC67710.1 - 3e-28 98.4 0.0 5.6e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CCC67710.1 - 2.3e-21 75.0 0.0 3.3e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PD40 PF07676.12 CCC67710.1 - 0.14 12.1 0.7 0.29 11.1 0.7 1.5 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Pkinase PF00069.25 CCC67711.1 - 2.1e-56 191.2 0.0 1.2e-55 188.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67711.1 - 4.5e-28 98.2 0.1 1.2e-19 70.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 CCC67711.1 - 6.9e-05 23.5 1.9 0.00018 22.2 1.9 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CCC67711.1 - 0.0018 17.3 0.2 0.0039 16.2 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CCC67711.1 - 0.0021 17.4 0.0 0.015 14.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CCC67711.1 - 0.0025 17.2 0.0 0.0049 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCC67711.1 - 0.041 13.8 0.0 0.3 11.0 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family RRM_1 PF00076.22 CCC67712.1 - 5.5e-66 218.3 12.7 3.1e-17 62.2 0.1 6.3 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCC67712.1 - 7.2e-06 25.6 0.0 0.0024 17.4 0.0 3.5 3 1 1 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCC67712.1 - 1.4e-05 24.8 0.0 0.25 11.2 0.0 4.0 4 0 0 4 4 4 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CCC67712.1 - 0.0003 20.7 0.1 1.5 8.9 0.0 4.1 5 0 0 5 5 5 2 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CCC67712.1 - 0.00082 19.5 0.1 9.2 6.5 0.0 4.6 4 0 0 4 4 4 1 RNA recognition motif SET_assoc PF11767.8 CCC67712.1 - 0.1 12.3 0.0 8.2 6.1 0.0 3.3 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated tRNA-synt_1 PF00133.22 CCC67713.1 - 7.4e-236 784.1 0.0 1.1e-234 780.3 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCC67713.1 - 4.4e-32 111.1 2.8 1.5e-31 109.4 2.8 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CCC67713.1 - 1.3e-15 57.0 0.3 3e-08 32.8 0.0 4.0 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CCC67713.1 - 2e-07 30.7 0.0 8.1e-07 28.7 0.0 3.7 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 CCC67713.1 - 0.00039 19.8 0.4 0.59 9.4 0.0 3.5 3 1 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 CCC67713.1 - 0.00047 20.4 8.6 0.00047 20.4 8.6 3.3 3 0 0 3 3 3 1 Valyl tRNA synthetase tRNA binding arm DUF3450 PF11932.8 CCC67713.1 - 0.84 8.9 9.6 1.5 8.1 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Vfa1 PF08432.10 CCC67713.1 - 6.6 7.0 17.7 1.9 8.8 2.9 3.1 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 CDP-OH_P_transf PF01066.21 CCC67714.1 - 3.3e-14 53.4 0.5 3.3e-14 53.4 0.5 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase TRAM_LAG1_CLN8 PF03798.16 CCC67715.1 - 3e-29 102.2 19.4 3e-29 102.2 19.4 1.6 2 0 0 2 2 2 1 TLC domain PIG-P PF08510.12 CCC67715.1 - 2.8 7.9 8.4 73 3.3 8.4 2.9 1 1 0 1 1 1 0 PIG-P RRG8 PF17068.5 CCC67716.1 - 1.6e-62 211.4 6.6 1.9e-62 211.2 6.6 1.0 1 0 0 1 1 1 1 Required for respiratory growth protein 8 mitochondrial TOC159_MAD PF11886.8 CCC67716.1 - 0.047 12.6 0.2 0.068 12.1 0.2 1.2 1 0 0 1 1 1 0 Translocase of chloroplast 159/132, membrane anchor domain VEGF_C PF14554.6 CCC67716.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 VEGF heparin-binding domain Fmp27_WPPW PF10359.9 CCC67717.1 - 4.6e-136 454.5 5.1 7.2e-136 453.8 5.1 1.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.9 CCC67717.1 - 9.8e-97 324.8 0.4 9.8e-97 324.8 0.4 2.2 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 CCC67717.1 - 9.7e-44 149.2 0.1 6.5e-43 146.5 0.0 2.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CCC67717.1 - 6.9e-41 139.7 1.3 2.4e-40 138.0 1.3 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CCC67717.1 - 8.6e-22 77.8 1.4 6.7e-20 71.7 0.0 3.5 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain HIP1_clath_bdg PF16515.5 CCC67717.1 - 0.0056 17.3 1.3 0.017 15.7 1.3 1.8 1 0 0 1 1 1 1 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF4200 PF13863.6 CCC67717.1 - 0.061 13.7 2.5 0.24 11.8 2.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) BLOC1_2 PF10046.9 CCC67717.1 - 0.62 10.4 4.2 7.4 6.9 1.6 3.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 CCC67717.1 - 3 8.4 10.8 0.38 11.3 0.8 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein IF-2B PF01008.17 CCC67718.1 - 5.4e-83 278.5 0.0 6.6e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cyclin_N PF00134.23 CCC67719.1 - 1.1e-43 148.0 0.3 2.9e-43 146.6 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCC67719.1 - 3e-16 59.6 0.0 8.3e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 CCC67720.1 - 7.1e-40 135.7 0.2 2.4e-39 134.0 0.1 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCC67720.1 - 2.2e-32 111.6 0.0 5.6e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Peptidase_M16 PF00675.20 CCC67721.1 - 9e-34 116.6 0.1 2.8e-32 111.8 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 CCC67721.1 - 2.8e-20 72.8 0.5 6.9e-20 71.5 0.5 1.7 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 CCC67721.1 - 3.5e-14 53.2 0.9 0.00021 21.4 0.0 5.0 4 1 0 4 4 4 3 Peptidase M16 inactive domain Ctr PF04145.15 CCC67722.1 - 4.4e-20 72.8 2.9 4.4e-20 72.8 2.9 2.9 3 0 0 3 3 3 1 Ctr copper transporter family UPF0242 PF06785.11 CCC67722.1 - 0.1 12.7 0.3 0.31 11.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4229 PF14012.6 CCC67722.1 - 2.7 8.2 10.7 0.12 12.5 4.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) SH2_2 PF14633.6 CCC67723.1 - 6.1e-69 231.7 1.4 6.1e-69 231.7 1.4 2.2 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.6 CCC67723.1 - 5.5e-63 211.3 0.0 2e-62 209.5 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HHH_7 PF14635.6 CCC67723.1 - 9.6e-47 157.6 0.1 2.9e-46 156.1 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.6 CCC67723.1 - 1e-33 116.2 2.4 1e-33 116.2 2.4 2.6 2 0 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.6 CCC67723.1 - 2.1e-19 69.9 25.0 2.1e-19 69.9 25.0 5.9 3 1 2 5 5 5 1 Acidic N-terminal SPT6 SH2 PF00017.24 CCC67723.1 - 1.6e-12 47.3 0.0 5.1e-12 45.7 0.0 2.0 1 0 0 1 1 1 1 SH2 domain HHH_9 PF17674.1 CCC67723.1 - 0.0011 19.9 0.8 0.0011 19.9 0.8 3.7 3 1 0 3 3 3 1 HHH domain LETM1 PF07766.13 CCC67724.1 - 4.1e-94 314.9 3.3 4.1e-94 314.9 3.3 1.9 2 0 0 2 2 2 1 LETM1-like protein Aldo_ket_red PF00248.21 CCC67725.1 - 1.3e-48 165.7 0.0 1.7e-48 165.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SF3a60_bindingd PF12108.8 CCC67725.1 - 0.12 12.3 0.5 0.3 11.0 0.5 1.7 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain Mito_carr PF00153.27 CCC67726.1 - 8.4e-54 179.5 2.8 2.9e-19 68.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.25 CCC67727.1 - 1.3e-09 38.4 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCC67727.1 - 1e-05 25.5 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCC67727.1 - 1.8e-05 25.0 0.0 2.7e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCC67727.1 - 8.7e-05 22.4 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Ribosom_S12_S23 PF00164.25 CCC67728.1 - 1.8e-51 172.5 0.3 2.3e-51 172.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Med26 PF08711.11 CCC67729.1 - 1.8e-13 50.3 0.1 1.8e-12 47.1 0.0 2.6 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Phasin PF05597.11 CCC67729.1 - 0.025 14.6 1.2 0.067 13.2 1.2 1.8 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tom5 PF10642.9 CCC67730.1 - 7.8e-21 73.8 0.4 8.6e-21 73.7 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Mcl1_mid PF12341.8 CCC67732.1 - 1.4e-85 287.3 0.0 4.1e-85 285.7 0.0 1.8 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 CCC67732.1 - 1.4e-06 28.5 2.7 0.33 11.3 0.3 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3598 PF12204.8 CCC67732.1 - 0.073 12.6 0.3 0.2 11.1 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3598) WD40 PF00400.32 CCC67732.1 - 0.46 11.4 5.5 0.94 10.5 0.1 4.2 6 0 0 6 6 6 0 WD domain, G-beta repeat WD40 PF00400.32 CCC67733.1 - 1.7e-14 54.0 1.8 6.1e-05 23.7 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat WD40_like PF17005.5 CCC67733.1 - 0.0014 18.0 0.2 0.94 8.7 0.0 3.5 4 0 0 4 4 4 1 WD40-like domain Tctex-1 PF03645.13 CCC67733.1 - 0.21 11.8 0.8 2.4 8.5 0.2 2.3 2 0 0 2 2 2 0 Tctex-1 family Ammonium_transp PF00909.21 CCC67734.1 - 8.6e-119 396.8 23.0 9.9e-119 396.6 23.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Phage_holin_2_1 PF04971.12 CCC67734.1 - 0.0083 16.1 0.2 0.0083 16.1 0.2 3.6 4 0 0 4 4 4 1 Bacteriophage P21 holin S YTH PF04146.15 CCC67735.1 - 3.7e-34 118.1 1.4 3.7e-34 118.1 1.4 2.3 2 2 0 2 2 2 1 YT521-B-like domain EVE PF01878.18 CCC67735.1 - 0.049 13.7 0.0 0.091 12.8 0.0 1.5 1 0 0 1 1 1 0 EVE domain CBFD_NFYB_HMF PF00808.23 CCC67736.1 - 0.00099 19.4 0.2 0.0012 19.1 0.2 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pyr_redox_2 PF07992.14 CCC67737.1 - 5.5e-07 29.1 0.0 3.1e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CCC67737.1 - 0.00014 22.1 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CCC67737.1 - 0.0072 15.9 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 CCC67737.1 - 0.015 15.3 0.0 0.039 13.9 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.20 CCC67737.1 - 0.033 14.3 0.0 2.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F1F0-ATPsyn_F PF10791.9 CCC67738.1 - 1.9e-40 137.2 0.3 2.1e-40 137.1 0.3 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.9 CCC67738.1 - 0.014 15.8 0.0 0.016 15.5 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f LSM PF01423.22 CCC67739.1 - 1.8e-16 59.6 0.0 2.1e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCC67739.1 - 0.0018 18.4 0.0 0.0031 17.6 0.0 1.4 1 1 1 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.7 CCC67739.1 - 0.044 13.9 0.0 0.053 13.6 0.0 1.3 1 1 0 1 1 1 0 Scd6-like Sm domain Complex1_LYR PF05347.15 CCC67740.1 - 5.7e-14 51.9 0.1 6.7e-14 51.7 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CCC67740.1 - 0.00016 22.3 0.2 0.00019 22.1 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like TPP_enzyme_N PF02776.18 CCC67741.1 - 2.3e-23 82.7 0.0 4e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCC67741.1 - 2e-17 63.2 0.0 3.9e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCC67741.1 - 2.5e-15 56.6 0.0 5.4e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RRM_1 PF00076.22 CCC67742.1 - 2.9e-11 43.0 0.0 5.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.6 CCC67742.1 - 0.0082 16.7 0.8 0.0082 16.7 0.8 2.9 2 1 0 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 DUF4748 PF15932.5 CCC67743.1 - 0.081 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4748) Mito_carr PF00153.27 CCC67744.1 - 2.2e-57 191.0 4.7 1e-19 70.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 CCC67744.1 - 0.0021 18.4 0.9 1.5 9.2 0.0 2.8 3 1 0 3 3 3 2 Tim17/Tim22/Tim23/Pmp24 family Ribosomal_60s PF00428.19 CCC67745.1 - 4.6e-23 81.6 7.3 5.4e-23 81.4 7.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Gpr1_Fun34_YaaH PF01184.19 CCC67746.1 - 8.9e-75 250.8 19.6 1.1e-74 250.5 19.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family GTP_EFTU PF00009.27 CCC67747.1 - 1e-67 227.5 0.3 1.4e-67 227.0 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CCC67747.1 - 3.6e-33 113.9 0.0 2e-32 111.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CCC67747.1 - 1.1e-21 76.6 0.0 3.1e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCC67747.1 - 2.4e-14 53.5 0.0 3.1e-13 49.9 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CCC67747.1 - 5.5e-14 52.0 0.0 2.5e-13 49.9 0.0 2.2 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CCC67747.1 - 0.00014 21.9 0.1 0.00029 20.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ERCC4 PF02732.15 CCC67748.1 - 2.3e-19 70.2 0.1 4.6e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 ERCC4 domain Sugar_tr PF00083.24 CCC67749.1 - 9.9e-101 337.8 30.5 2.3e-55 188.3 8.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 CCC67749.1 - 1.7e-34 119.3 53.8 1.2e-31 110.0 26.6 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 CCC67749.1 - 0.024 15.2 3.2 0.024 15.2 3.2 3.6 3 1 0 3 3 3 0 Phage holin family 2 BAR PF03114.18 CCC67750.1 - 1.3e-65 221.4 6.8 1.6e-65 221.1 6.8 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.28 CCC67750.1 - 3.1e-14 52.3 0.0 5.4e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCC67750.1 - 5.4e-11 42.2 0.2 8.9e-11 41.5 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCC67750.1 - 4.8e-07 29.4 0.0 9.1e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF755 PF05501.11 CCC67750.1 - 0.024 14.9 0.7 0.024 14.9 0.7 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) BRE1 PF08647.11 CCC67750.1 - 0.18 11.9 6.2 13 6.0 3.3 2.7 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Lebercilin PF15619.6 CCC67750.1 - 2.5 7.7 10.8 4.5 6.9 6.2 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease RhoGAP PF00620.27 CCC67751.1 - 3.7e-32 111.3 1.4 3.6e-31 108.1 1.4 2.2 1 1 0 1 1 1 1 RhoGAP domain Coilin_N PF15862.5 CCC67751.1 - 0.00024 20.9 0.5 0.00024 20.9 0.5 3.4 4 1 0 4 4 4 1 Coilin N-terminus Phlebovirus_NSM PF07246.11 CCC67751.1 - 0.0046 16.4 1.6 0.0082 15.5 1.6 1.4 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M D123 PF07065.14 CCC67751.1 - 0.54 9.4 10.3 0.015 14.4 3.4 1.8 2 0 0 2 2 2 0 D123 DUF4710 PF15828.5 CCC67751.1 - 0.72 10.0 5.8 2.5 8.3 5.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) ThiF PF00899.21 CCC67752.1 - 1.5e-67 227.5 0.0 2e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 CCC67752.1 - 4.7e-06 26.7 14.9 0.00069 19.6 0.4 3.2 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 CCC67752.1 - 0.011 16.3 1.6 0.025 15.1 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.6 CCC67752.1 - 0.065 13.7 0.0 0.41 11.1 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding TFIID-18kDa PF02269.16 CCC67753.1 - 7.7e-37 125.2 1.1 3.9e-36 123.0 0.1 2.4 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit KH_8 PF17903.1 CCC67754.1 - 1.7e-05 24.8 0.0 3.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CCC67754.1 - 0.08 12.8 0.3 0.2 11.5 0.3 1.7 1 0 0 1 1 1 0 KH domain She9_MDM33 PF05546.11 CCC67755.1 - 5.5e-85 284.2 10.2 5.5e-85 284.2 10.2 2.5 2 1 0 2 2 2 1 She9 / Mdm33 family ApoLp-III PF07464.11 CCC67755.1 - 0.00036 20.6 6.0 0.096 12.8 0.7 2.6 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) PsbH PF00737.20 CCC67755.1 - 0.028 14.2 0.5 0.059 13.1 0.5 1.5 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Uso1_p115_C PF04871.13 CCC67755.1 - 0.047 14.1 1.4 0.047 14.1 1.4 3.6 4 0 0 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF948 PF06103.11 CCC67755.1 - 0.21 11.9 4.7 0.97 9.7 0.3 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PspA_IM30 PF04012.12 CCC67755.1 - 0.55 9.8 9.9 2.4 7.7 3.5 2.9 3 1 0 3 3 3 0 PspA/IM30 family Seryl_tRNA_N PF02403.22 CCC67755.1 - 6 7.1 19.0 12 6.2 7.2 3.5 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Fzo_mitofusin PF04799.13 CCC67755.1 - 8.1 6.0 12.8 0.22 11.1 0.4 3.4 4 1 1 5 5 5 0 fzo-like conserved region AAA PF00004.29 CCC67756.1 - 2.8e-46 157.2 0.0 9.3e-46 155.5 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CCC67756.1 - 7.4e-09 35.4 0.1 5.8e-08 32.6 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 CCC67756.1 - 3.8e-08 33.6 0.0 7.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCC67756.1 - 5.3e-08 32.9 0.1 2e-07 31.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCC67756.1 - 1.1e-07 32.4 0.0 2.1e-05 25.0 0.0 3.1 2 1 0 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CCC67756.1 - 9.7e-05 21.6 0.0 0.00017 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 CCC67756.1 - 0.00011 22.4 3.8 0.0024 18.1 0.0 2.8 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.12 CCC67756.1 - 0.00026 20.8 0.0 0.00072 19.3 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CCC67756.1 - 0.00029 21.4 0.1 0.0062 17.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain NTPase_1 PF03266.15 CCC67756.1 - 0.00039 20.4 0.2 0.0015 18.5 0.0 2.0 3 0 0 3 3 3 1 NTPase AAA_lid_3 PF17862.1 CCC67756.1 - 0.00044 20.0 0.2 0.0012 18.7 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_14 PF13173.6 CCC67756.1 - 0.00066 19.7 0.1 0.0034 17.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 CCC67756.1 - 0.0014 18.6 0.0 0.0026 17.8 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 CCC67756.1 - 0.0018 18.0 0.0 0.0045 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CCC67756.1 - 0.0024 18.2 0.0 0.0049 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 CCC67756.1 - 0.0024 17.4 0.0 0.021 14.4 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 CCC67756.1 - 0.0025 17.1 0.0 0.005 16.1 0.0 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_3 PF07726.11 CCC67756.1 - 0.0028 17.5 0.0 0.0075 16.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 CCC67756.1 - 0.0043 16.8 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain TniB PF05621.11 CCC67756.1 - 0.0054 16.1 0.0 0.37 10.2 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein AAA_33 PF13671.6 CCC67756.1 - 0.0056 16.9 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CCC67756.1 - 0.0068 15.8 0.0 0.018 14.4 0.0 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CCC67756.1 - 0.0076 16.0 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.12 CCC67756.1 - 0.012 15.5 0.1 0.099 12.6 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_28 PF13521.6 CCC67756.1 - 0.014 15.7 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 CCC67756.1 - 0.018 14.8 0.1 0.069 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 CCC67756.1 - 0.021 14.7 0.1 0.32 10.9 0.0 2.5 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 CCC67756.1 - 0.032 14.0 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 CCC67756.1 - 0.044 13.3 0.6 0.37 10.3 0.1 2.6 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CCC67756.1 - 0.098 11.9 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 CCC67756.1 - 0.12 12.7 0.1 0.38 11.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain DnaB_C PF03796.15 CCC67756.1 - 0.97 8.7 4.3 3 7.1 0.7 2.7 2 1 0 3 3 3 0 DnaB-like helicase C terminal domain IBN_N PF03810.19 CCC67757.1 - 3.4e-16 58.9 0.2 1e-15 57.3 0.2 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.10 CCC67757.1 - 1.9e-07 30.3 5.6 3e-07 29.6 3.4 2.5 2 1 0 2 2 2 1 Cse1 CARD_2 PF16739.5 CCC67757.1 - 0.0005 20.0 0.0 0.0059 16.6 0.0 2.6 2 0 0 2 2 2 1 Caspase recruitment domain EAF PF09816.9 CCC67757.1 - 0.018 15.5 0.0 0.037 14.4 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription elongation factor RTP1_C1 PF10363.9 CCC67757.1 - 0.018 15.2 0.2 5.2 7.3 0.0 3.8 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Vac14_Fab1_bd PF12755.7 CCC67757.1 - 0.039 14.5 0.4 0.49 11.0 0.1 3.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Telomerase_RBD PF12009.8 CCC67757.1 - 0.086 12.9 0.1 0.33 11.1 0.1 2.0 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain DLH PF01738.18 CCC67757.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF5503 PF17607.2 CCC67757.1 - 0.16 12.3 4.0 12 6.2 0.2 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5503) Spectrin_like PF18373.1 CCC67757.1 - 0.23 11.6 1.6 13 5.9 0.1 3.2 3 0 0 3 3 3 0 Spectrin like domain DUF5487 PF17589.2 CCC67757.1 - 0.53 10.6 3.8 0.89 9.9 0.8 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5487) Pribosyltran PF00156.27 CCC67758.1 - 4.8e-08 32.7 0.0 1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Syntaxin-6_N PF09177.11 CCC67758.1 - 0.12 13.0 0.1 0.21 12.2 0.1 1.4 1 0 0 1 1 1 0 Syntaxin 6, N-terminal 3Beta_HSD PF01073.19 CCC67758.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Fe-ADH PF00465.19 CCC67758.1 - 0.16 10.7 0.0 0.27 10.0 0.0 1.3 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase IU_nuc_hydro PF01156.19 CCC67759.1 - 7.1e-70 236.0 0.0 8.4e-70 235.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.22 CCC67760.1 - 7.8e-56 189.7 0.1 9.8e-56 189.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 SRP_TPR_like PF17004.5 CCC67760.1 - 0.13 12.2 1.2 0.9 9.6 1.1 2.4 2 1 0 2 2 2 0 Putative TPR-like repeat DIT1_PvcA PF05141.12 CCC67761.1 - 6.8e-96 321.0 0.0 9.9e-96 320.4 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DUF4288 PF14119.6 CCC67761.1 - 0.067 13.6 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) S1 PF00575.23 CCC67762.1 - 4.9e-18 65.3 0.1 7e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 CCC67762.1 - 2.4e-16 59.9 0.0 5e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.12 CCC67762.1 - 9.1e-06 25.9 0.0 1.7e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 Ribosomal_L23 PF00276.20 CCC67763.1 - 3.4e-10 40.2 0.0 7.2e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 ABC2_membrane PF01061.24 CCC67764.1 - 6.8e-83 277.2 54.3 7.2e-43 146.5 23.6 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CCC67764.1 - 1.3e-38 132.6 0.1 3.4e-18 66.5 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 CCC67764.1 - 3.5e-35 119.8 2.0 2.1e-29 101.3 0.1 3.2 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CCC67764.1 - 2.1e-18 66.7 0.0 5.6e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 CCC67764.1 - 4.1e-07 29.8 0.7 6.4e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CCC67764.1 - 7.1e-07 29.8 0.1 0.00012 22.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 CCC67764.1 - 1.6e-06 27.5 32.4 0.0024 17.0 10.7 2.6 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_18 PF13238.6 CCC67764.1 - 0.00012 22.6 0.0 0.02 15.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCC67764.1 - 0.00012 22.0 0.1 0.0047 16.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 CCC67764.1 - 0.00017 21.8 0.1 0.13 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 CCC67764.1 - 0.00067 19.6 0.0 0.18 11.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CCC67764.1 - 0.001 19.3 0.2 0.42 10.9 0.1 2.9 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CCC67764.1 - 0.0017 18.1 3.1 0.0082 15.9 0.1 2.9 3 0 0 3 3 3 1 P-loop containing region of AAA domain SMC_N PF02463.19 CCC67764.1 - 0.0018 17.8 0.1 0.14 11.5 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.12 CCC67764.1 - 0.0025 17.8 0.3 2.3 8.1 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 CCC67764.1 - 0.0041 17.4 1.0 0.22 11.8 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CCC67764.1 - 0.0044 17.5 0.1 0.046 14.2 0.0 2.6 3 0 0 3 3 2 1 AAA domain cobW PF02492.19 CCC67764.1 - 0.018 14.6 1.3 3.5 7.2 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain OCD_Mu_crystall PF02423.15 CCC67764.1 - 0.028 13.4 0.0 0.62 8.9 0.0 2.2 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family AAA PF00004.29 CCC67764.1 - 0.053 13.9 0.3 6.2 7.3 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CCC67764.1 - 0.057 13.1 3.4 3.6 7.3 0.4 3.0 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.15 CCC67764.1 - 0.11 11.8 0.0 3.1 7.0 0.0 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain NB-ARC PF00931.22 CCC67764.1 - 0.12 11.6 0.4 11 5.1 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain TRAPPC9-Trs120 PF08626.11 CCC67765.1 - 0 1072.4 25.9 0 1072.1 25.9 1.0 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Formyl_trans_N PF00551.19 CCC67766.1 - 2.6e-52 177.2 0.0 3.1e-52 177.0 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase PINIT PF14324.6 CCC67767.1 - 1.2e-33 116.5 0.4 1.2e-33 116.5 0.4 1.8 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.20 CCC67767.1 - 2.1e-21 75.4 8.1 3.9e-21 74.5 8.1 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 CCC67767.1 - 2e-05 24.3 2.4 7.1e-05 22.6 2.4 2.0 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CCC67767.1 - 0.022 14.8 5.4 0.05 13.6 5.4 1.7 1 0 0 1 1 1 0 RING-type zinc-finger SAP PF02037.27 CCC67767.1 - 0.028 14.2 0.1 0.056 13.2 0.1 1.5 1 0 0 1 1 1 0 SAP domain Prok-RING_4 PF14447.6 CCC67767.1 - 0.14 12.1 1.5 0.42 10.5 1.5 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CCC67767.1 - 0.23 11.4 5.1 0.51 10.2 5.1 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCC67767.1 - 0.71 10.3 4.4 1.3 9.4 4.4 1.5 1 0 0 1 1 1 0 Ring finger domain ICMT PF04140.14 CCC67768.1 - 2.9e-29 101.3 1.2 4.7e-29 100.7 1.2 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 CCC67768.1 - 2.6e-13 50.3 3.0 5.5e-12 46.0 1.2 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 CCC67768.1 - 0.00011 21.8 0.2 0.00016 21.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.11 CCC67768.1 - 0.00044 19.8 0.1 0.00077 19.0 0.1 1.4 1 0 0 1 1 1 1 NnrU protein DUF2569 PF10754.9 CCC67768.1 - 0.098 13.1 9.7 1.1 9.7 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DER1 PF04511.15 CCC67769.1 - 1.3e-36 126.4 11.1 1.6e-36 126.1 11.1 1.1 1 0 0 1 1 1 1 Der1-like family Nop25 PF09805.9 CCC67770.1 - 1.4e-38 132.5 18.4 1.4e-38 132.5 18.4 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) EXS PF03124.14 CCC67771.1 - 3.9e-52 177.6 26.9 4.6e-52 177.4 26.9 1.0 1 0 0 1 1 1 1 EXS family Peptidase_M28 PF04389.17 CCC67772.1 - 1.3e-26 93.5 0.0 2.2e-26 92.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 CCC67772.1 - 0.00014 21.6 0.0 0.00028 20.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 ATP-synt_D PF01813.17 CCC67773.1 - 2.8e-70 236.1 3.5 3.8e-70 235.7 3.5 1.2 1 0 0 1 1 1 1 ATP synthase subunit D APG6_N PF17675.1 CCC67773.1 - 0.024 15.2 7.5 0.03 14.8 5.5 1.9 2 0 0 2 2 2 0 Apg6 coiled-coil region BLOC1_2 PF10046.9 CCC67773.1 - 0.49 10.7 0.1 0.49 10.7 0.1 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 RICH PF05062.12 CCC67773.1 - 0.66 10.4 6.9 0.36 11.2 2.5 2.4 2 1 0 2 2 2 0 RICH domain Ribosomal_L6e PF01159.19 CCC67773.1 - 1.5 9.4 5.7 0.43 11.1 2.3 1.8 2 0 0 2 2 2 0 Ribosomal protein L6e TPR_14 PF13428.6 CCC67774.1 - 5.4e-08 33.0 0.0 0.0042 17.8 0.0 4.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCC67774.1 - 0.00021 21.2 0.0 0.0012 18.9 0.0 2.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCC67774.1 - 0.0012 18.7 1.3 0.0031 17.5 0.3 2.4 2 0 0 2 2 1 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 CCC67774.1 - 0.0043 17.0 15.1 0.27 11.2 1.2 6.2 4 3 3 7 7 7 2 Mad3/BUB1 homology region 1 TPR_12 PF13424.6 CCC67774.1 - 0.0083 16.4 0.2 0.042 14.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCC67774.1 - 0.027 15.1 0.0 0.064 13.9 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCC67774.1 - 0.056 13.5 0.2 1.4 9.1 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCC67774.1 - 0.066 13.7 0.0 0.83 10.2 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 CCC67774.1 - 0.07 13.0 0.2 0.39 10.6 0.2 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat HTH_16 PF12645.7 CCC67774.1 - 0.074 13.1 0.9 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain TPR_6 PF13174.6 CCC67774.1 - 0.13 12.9 0.1 19 6.2 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.14 CCC67775.1 - 2.4e-21 75.3 1.0 4.7e-21 74.4 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CCC67775.1 - 1.8e-16 60.4 0.9 4.3e-16 59.2 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain IMS PF00817.20 CCC67776.1 - 6e-42 143.2 0.0 2.2e-41 141.3 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family zf_UBZ PF18439.1 CCC67776.1 - 1.4e-06 27.8 1.3 3.2e-06 26.6 1.3 1.7 1 0 0 1 1 1 1 Ubiquitin-Binding Zinc Finger IMS_HHH PF11798.8 CCC67776.1 - 0.0013 19.0 0.0 0.0032 17.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2_jaz PF12171.8 CCC67776.1 - 0.015 15.6 0.9 0.041 14.2 0.9 1.9 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding RRM_5 PF13893.6 CCC67777.1 - 4e-12 45.8 0.0 4.6e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 CCC67777.1 - 3.2e-09 36.5 0.2 6.2e-09 35.5 0.2 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCC67777.1 - 0.045 13.6 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif DHNA PF04038.12 CCC67777.1 - 0.093 13.3 0.1 0.11 13.0 0.1 1.2 1 0 0 1 1 1 0 Dihydroneopterin aldolase Pkinase PF00069.25 CCC67778.1 - 5.2e-36 124.4 0.0 7.7e-36 123.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67778.1 - 6e-13 48.7 0.0 1.1e-12 47.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCC67778.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCC67778.1 - 0.015 14.6 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 Kinase-like HLH PF00010.26 CCC67779.1 - 1.1e-11 44.5 3.4 2.6e-11 43.3 3.4 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain bZIP_1 PF00170.21 CCC67779.1 - 0.022 14.9 3.3 0.022 14.9 3.3 2.8 3 1 0 3 3 3 0 bZIP transcription factor Csm1_N PF18504.1 CCC67779.1 - 0.031 14.6 1.4 0.031 14.6 1.4 3.3 3 0 0 3 3 3 0 Csm1 N-terminal domain LicD PF04991.13 CCC67780.1 - 3e-50 171.5 2.8 3e-50 171.5 2.8 2.5 2 0 0 2 2 2 1 LicD family DUF87 PF01935.17 CCC67780.1 - 0.012 15.7 3.3 0.032 14.3 0.2 2.4 2 0 0 2 2 2 0 Helicase HerA, central domain DUF5449 PF17528.2 CCC67780.1 - 0.17 11.7 1.5 0.3 10.8 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5449) CN_hydrolase PF00795.22 CCC67781.1 - 8.7e-19 67.9 0.0 2.3e-17 63.2 0.0 2.1 2 0 0 2 2 2 2 Carbon-nitrogen hydrolase PRCC PF10253.9 CCC67782.1 - 1.5e-07 32.4 5.6 2.5e-07 31.7 5.6 1.5 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Cpn60_TCP1 PF00118.24 CCC67784.1 - 1.1e-153 512.4 2.9 1.3e-153 512.2 2.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MIT_C PF16565.5 CCC67784.1 - 0.049 13.6 0.0 0.31 11.0 0.0 2.4 3 0 0 3 3 3 0 Phospholipase D-like domain at C-terminus of MIT Actin PF00022.19 CCC67785.1 - 1.3e-89 300.7 0.0 4e-87 292.5 0.0 2.1 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CCC67785.1 - 1.7e-05 23.8 0.0 0.019 13.8 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 CCC67785.1 - 0.0015 18.9 0.0 0.0053 17.2 0.0 2.0 2 1 0 2 2 2 1 Cell division protein FtsA FAT PF02259.23 CCC67786.1 - 4e-129 430.8 6.2 4e-129 430.8 6.2 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 CCC67786.1 - 1.8e-71 240.9 0.1 3.9e-71 239.8 0.1 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CCC67786.1 - 1.7e-54 184.0 19.6 4e-53 179.6 1.4 6.5 5 1 0 6 6 6 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CCC67786.1 - 4.7e-39 132.8 1.1 4.7e-39 132.8 1.1 2.6 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 CCC67786.1 - 1.1e-15 57.7 1.9 0.0003 21.1 0.0 8.6 8 1 0 8 8 7 3 HEAT repeats FATC PF02260.20 CCC67786.1 - 1.3e-15 56.9 0.1 3.2e-15 55.6 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CCC67786.1 - 2.5e-13 49.0 3.9 0.002 18.2 0.0 10.4 12 0 0 12 12 11 1 HEAT repeat HEAT_EZ PF13513.6 CCC67786.1 - 4.5e-10 39.8 0.0 0.0019 18.6 0.0 7.3 5 1 1 6 6 6 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CCC67786.1 - 2.6e-05 24.7 3.5 1.1 10.0 0.0 6.2 5 1 1 6 6 5 1 Vacuolar 14 Fab1-binding region IFRD PF05004.13 CCC67786.1 - 5.1e-05 22.5 2.7 0.055 12.6 0.0 4.5 3 2 1 4 4 4 1 Interferon-related developmental regulator (IFRD) DUF3437 PF11919.8 CCC67786.1 - 0.00026 20.8 0.2 2.2 8.3 0.0 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3437) Cnd1 PF12717.7 CCC67786.1 - 0.028 14.4 11.1 12 5.9 0.0 6.7 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 DUF4727 PF15856.5 CCC67786.1 - 0.11 12.1 1.3 1.4 8.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4727) TFIID-18kDa PF02269.16 CCC67786.1 - 0.12 12.4 0.1 3.4 7.8 0.0 2.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Arm PF00514.23 CCC67786.1 - 0.27 11.3 2.9 85 3.4 0.1 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat FANCI_S2 PF14676.6 CCC67786.1 - 2 8.7 5.1 69 3.7 0.0 4.6 4 0 0 4 4 4 0 FANCI solenoid 2 CLASP_N PF12348.8 CCC67786.1 - 2.7 7.5 12.0 0.52 9.8 0.6 5.1 4 2 0 5 5 5 0 CLASP N terminal Yae1_N PF09811.9 CCC67787.1 - 2e-13 49.8 0.1 3.4e-13 49.1 0.1 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Romo1 PF10247.9 CCC67787.1 - 0.022 15.1 0.0 0.032 14.6 0.0 1.2 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 AAA PF00004.29 CCC67788.1 - 3.9e-17 62.9 0.0 1e-16 61.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 CCC67788.1 - 3.4e-16 59.4 0.0 9.6e-16 58.0 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 CCC67788.1 - 4.8e-14 52.5 0.0 2.4e-12 47.0 0.0 2.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 CCC67788.1 - 1.2e-08 35.1 0.0 2.3e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 CCC67788.1 - 2.3e-06 27.8 0.1 6.9e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 CCC67788.1 - 2.7e-05 24.0 0.0 7.2e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCC67788.1 - 4.1e-05 23.9 0.1 0.0012 19.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.6 CCC67788.1 - 6.1e-05 22.9 0.1 9.2e-05 22.4 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCC67788.1 - 0.0001 22.7 0.0 0.0038 17.6 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 CCC67788.1 - 0.00015 21.8 0.0 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CCC67788.1 - 0.00066 19.1 0.0 0.011 15.1 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 CCC67788.1 - 0.003 17.9 0.1 0.022 15.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CCC67788.1 - 0.0042 16.8 0.0 0.015 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 CCC67788.1 - 0.0044 17.0 0.0 0.021 14.8 0.0 2.0 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit DUF815 PF05673.13 CCC67788.1 - 0.0054 15.9 0.0 0.0098 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CCC67788.1 - 0.0083 16.1 0.1 0.085 12.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CCC67788.1 - 0.0086 15.8 0.0 0.022 14.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCC67788.1 - 0.0094 15.5 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 CCC67788.1 - 0.013 16.0 0.1 0.083 13.4 0.0 2.3 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 CCC67788.1 - 0.018 14.3 0.0 0.066 12.4 0.0 1.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.6 CCC67788.1 - 0.036 14.6 0.0 0.077 13.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain TIP49_C PF17856.1 CCC67788.1 - 0.037 14.2 0.3 0.1 12.8 0.3 1.7 1 0 0 1 1 1 0 TIP49 AAA-lid domain AAA_3 PF07726.11 CCC67788.1 - 0.043 13.7 0.0 0.46 10.4 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 CCC67788.1 - 0.044 14.0 0.0 0.094 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CCC67788.1 - 0.078 13.4 0.6 0.24 11.8 0.0 2.2 3 1 0 3 3 2 0 RNA helicase DEAD PF00270.29 CCC67788.1 - 0.13 12.0 0.1 1.3 8.8 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase RNA12 PF10443.9 CCC67789.1 - 0.78 8.4 7.8 0.033 12.9 1.0 2.0 2 0 0 2 2 2 0 RNA12 protein PAC2 PF09754.9 CCC67790.1 - 2.4e-23 83.3 0.0 3.1e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 PAC2 family PEMT PF04191.13 CCC67791.1 - 8.3e-34 116.2 2.6 1.8e-33 115.1 2.6 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase CENP-C_C PF11699.8 CCC67792.1 - 6.1e-26 90.5 6.4 2.1e-25 88.7 1.4 2.9 2 1 1 3 3 3 1 Mif2/CENP-C like Mif2_N PF15624.6 CCC67792.1 - 1.2e-05 26.0 0.1 1.2e-05 26.0 0.1 2.5 2 1 0 2 2 2 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.11 CCC67792.1 - 0.00028 20.5 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Tombus_movement PF05318.12 CCC67792.1 - 0.01 16.7 1.9 0.025 15.4 0.2 2.5 2 0 0 2 2 2 0 Tombusvirus movement protein Lipase_chap PF03280.14 CCC67792.1 - 0.037 14.0 0.0 0.086 12.8 0.0 1.6 2 0 0 2 2 2 0 Proteobacterial lipase chaperone protein Pkinase PF00069.25 CCC67793.1 - 1.1e-71 241.3 0.0 2.2e-71 240.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67793.1 - 1.2e-48 165.7 0.0 1.9e-48 165.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 CCC67793.1 - 2.8e-14 53.2 0.0 7.3e-14 51.9 0.0 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 CCC67793.1 - 5.6e-08 32.5 0.3 3.6e-07 29.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CCC67793.1 - 0.0004 19.3 1.4 0.00056 18.8 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 CCC67793.1 - 0.064 13.2 0.0 0.17 11.8 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L10 PF00466.20 CCC67794.1 - 4e-19 68.6 0.1 6.4e-19 68.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 CCC67794.1 - 7.3e-19 67.5 0.0 1.2e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_S2 PF00318.20 CCC67796.1 - 1.3e-68 230.4 0.0 4.3e-68 228.8 0.0 1.9 2 1 0 2 2 2 1 Ribosomal protein S2 SIS_2 PF13580.6 CCC67796.1 - 0.0041 17.1 0.0 0.0082 16.2 0.0 1.5 1 0 0 1 1 1 1 SIS domain Mito_carr PF00153.27 CCC67797.1 - 4.3e-44 148.4 7.0 1.6e-17 63.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Syja_N PF02383.18 CCC67798.1 - 1e-84 284.6 0.6 1.4e-84 284.1 0.6 1.2 1 0 0 1 1 1 1 SacI homology domain Gly_transf_sug PF04488.15 CCC67799.1 - 2e-13 50.8 0.2 1e-12 48.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Dak2 PF02734.17 CCC67799.1 - 0.0095 15.9 0.1 0.014 15.3 0.1 1.2 1 0 0 1 1 1 1 DAK2 domain Baculo_PEP_C PF04513.12 CCC67799.1 - 0.06 13.4 3.6 0.12 12.4 3.6 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3139 PF11337.8 CCC67799.1 - 0.32 11.7 2.1 0.71 10.6 1.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3139) MRP-S32 PF10210.9 CCC67799.1 - 0.59 10.7 3.2 1 10.0 1.3 2.2 2 1 0 2 2 2 0 Mitochondrial 28S ribosomal protein S32 DUF4446 PF14584.6 CCC67799.1 - 8.1 6.4 6.7 1.8 8.5 3.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Mog1 PF04603.12 CCC67800.1 - 3.5e-42 144.1 1.0 4.2e-42 143.8 1.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein dUTPase PF00692.19 CCC67801.1 - 3.5e-44 149.6 0.0 3.9e-44 149.4 0.0 1.0 1 0 0 1 1 1 1 dUTPase MIS13 PF08202.11 CCC67802.1 - 7.6e-70 235.6 14.7 7.6e-70 235.6 14.7 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family ANAPC4_WD40 PF12894.7 CCC67803.1 - 2.4e-08 34.2 0.4 0.00054 20.2 0.1 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCC67803.1 - 0.00018 22.2 12.3 0.98 10.4 0.3 6.2 6 1 0 6 6 6 2 WD domain, G-beta repeat baeRF_family3 PF18845.1 CCC67803.1 - 0.018 15.3 0.1 0.03 14.6 0.1 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 Lactonase PF10282.9 CCC67803.1 - 0.032 13.5 0.0 0.07 12.4 0.0 1.6 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PQQ PF01011.21 CCC67803.1 - 0.094 12.7 1.4 2.2 8.3 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat Asp PF00026.23 CCC67804.1 - 3.5e-73 246.8 3.2 5e-73 246.3 3.2 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCC67804.1 - 2.2e-12 47.6 1.1 2.2e-12 47.6 1.1 2.1 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal BAG PF02179.16 CCC67805.1 - 1.1e-16 61.0 1.7 2e-16 60.1 1.7 1.5 1 0 0 1 1 1 1 BAG domain eIF3_subunit PF08597.10 CCC67805.1 - 0.035 14.0 0.4 0.051 13.5 0.4 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit HEAT PF02985.22 CCC67806.1 - 0.013 15.7 0.0 0.44 10.9 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat Ribosomal_L2_C PF03947.18 CCC67807.1 - 7.8e-45 152.1 3.0 1.4e-44 151.3 3.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CCC67807.1 - 1.1e-13 51.0 0.2 2.6e-13 49.7 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L29e PF01779.17 CCC67808.1 - 8e-24 83.7 9.4 1.1e-23 83.3 9.4 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family His_biosynth PF00977.21 CCC67809.1 - 3.9e-26 91.9 0.0 4.8e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein Phage_CI_C PF16452.5 CCC67809.1 - 0.012 15.9 0.1 8.2 6.8 0.0 2.5 1 1 1 2 2 2 0 Bacteriophage CI repressor C-terminal domain BtpA PF03437.15 CCC67809.1 - 0.061 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 BtpA family nos_propeller PF18764.1 CCC67809.1 - 0.12 12.3 0.0 0.58 10.1 0.0 2.2 2 0 0 2 2 2 0 Nitrous oxide reductase propeller repeat Aldolase PF01081.19 CCC67809.1 - 0.16 11.3 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 KDPG and KHG aldolase Tim44 PF04280.15 CCC67810.1 - 8.2e-37 126.6 0.6 2.8e-36 124.8 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain bZIP_1 PF00170.21 CCC67811.1 - 3.2e-05 23.9 13.7 6.9e-05 22.9 13.7 1.6 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.13 CCC67811.1 - 0.33 10.8 4.6 0.31 10.9 2.7 1.9 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain bZIP_2 PF07716.15 CCC67811.1 - 1.8 8.7 18.9 0.09 12.9 13.3 1.8 2 0 0 2 2 2 0 Basic region leucine zipper Form_Nir_trans PF01226.17 CCC67812.1 - 7.5e-57 192.4 22.2 9.4e-57 192.1 22.2 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter BRAP2 PF07576.12 CCC67813.1 - 7.7e-31 106.3 0.6 3.5e-30 104.2 0.1 2.1 2 0 0 2 2 2 1 BRCA1-associated protein 2 zf-UBP PF02148.19 CCC67813.1 - 1.1e-21 77.0 8.4 2.8e-21 75.6 8.4 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 CCC67813.1 - 1.3e-07 31.8 14.7 1.3e-07 31.8 14.7 2.1 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCC67813.1 - 7.1e-06 25.8 14.6 1.9e-05 24.4 14.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCC67813.1 - 7.1e-05 22.5 8.9 0.00022 20.9 8.9 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CCC67813.1 - 0.00011 22.1 11.5 0.00064 19.7 11.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 CCC67813.1 - 0.00031 21.0 9.9 0.00031 21.0 9.9 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 CCC67813.1 - 0.00062 19.7 12.8 0.00062 19.7 12.8 2.4 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CCC67813.1 - 0.001 18.9 14.5 0.001 18.9 14.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CCC67813.1 - 0.0012 18.7 10.5 0.0012 18.7 10.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-UBP_var PF17807.1 CCC67813.1 - 0.0084 15.8 1.1 0.02 14.7 1.1 1.6 1 0 0 1 1 1 1 Variant UBP zinc finger Prok-RING_4 PF14447.6 CCC67813.1 - 0.02 14.8 14.3 0.02 14.8 14.3 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 CCC67813.1 - 0.025 14.6 6.0 0.091 12.8 6.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CCC67813.1 - 0.23 11.3 11.8 0.73 9.7 11.8 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2344 PF10105.9 CCC67813.1 - 0.74 9.6 6.0 1.4 8.7 6.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Cnn_1N PF07989.11 CCC67813.1 - 3.3 7.9 19.4 1.3 9.2 6.8 2.6 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 Spore_III_AB PF09548.10 CCC67813.1 - 5.8 7.0 11.4 15 5.7 11.4 1.6 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) LMBR1 PF04791.16 CCC67813.1 - 7.3 5.4 8.1 10 4.9 8.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Pribosyl_synth PF14572.6 CCC67814.1 - 1.8e-41 142.2 3.5 1.1e-35 123.4 2.4 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CCC67814.1 - 3e-38 130.4 0.2 1.9e-37 127.8 0.0 2.2 2 1 1 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CCC67814.1 - 1.4e-16 60.4 1.1 4.5e-16 58.8 1.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCC67814.1 - 0.024 14.1 0.1 0.038 13.4 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.8 CCC67814.1 - 0.098 12.6 1.9 0.2 11.6 1.9 1.5 1 0 0 1 1 1 0 Chlorosome envelope protein C Crisp PF08562.10 CCC67814.1 - 0.13 12.9 0.2 0.39 11.3 0.0 1.8 2 0 0 2 2 2 0 Crisp UDPGP PF01704.18 CCC67815.1 - 4.2e-186 618.5 0.0 6.8e-186 617.9 0.0 1.3 2 0 0 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase Zn_clus PF00172.18 CCC67816.1 - 4.3e-07 29.9 10.5 7.2e-07 29.2 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OTU PF02338.19 CCC67817.1 - 5.8e-30 104.4 0.4 1.8e-29 102.8 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 CCC67817.1 - 6e-05 22.6 0.1 6e-05 22.6 0.1 3.0 2 1 0 2 2 2 1 Peptidase C65 Otubain L31 PF09784.9 CCC67817.1 - 1 9.8 8.6 2.7 8.4 1.4 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 YchF-GTPase_C PF06071.13 CCC67818.1 - 2.6e-29 101.2 0.0 6.7e-29 99.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 CCC67818.1 - 3.7e-17 62.4 0.2 1.1e-16 60.9 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCC67818.1 - 0.00029 20.4 0.0 0.0007 19.2 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.21 CCC67818.1 - 0.03 14.4 0.0 0.065 13.3 0.0 1.6 1 0 0 1 1 1 0 TGS domain AAA_14 PF13173.6 CCC67818.1 - 0.14 12.2 1.3 0.52 10.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain Ribosomal_S10 PF00338.22 CCC67819.1 - 2.2e-24 85.5 0.7 2.7e-24 85.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e SSF PF00474.17 CCC67820.1 - 1.9e-16 60.0 30.0 3.3e-16 59.2 30.0 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2207 PF09972.9 CCC67820.1 - 0.015 14.1 0.2 0.015 14.1 0.2 4.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF3087 PF11286.8 CCC67820.1 - 0.11 12.0 0.3 0.51 9.8 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3087) NifU PF01106.17 CCC67821.1 - 3.8e-25 87.8 0.0 6.5e-25 87.1 0.0 1.4 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 CCC67821.1 - 2.2e-20 72.5 0.1 5.4e-20 71.2 0.1 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal YojJ PF10372.9 CCC67821.1 - 0.0025 17.9 0.5 0.0063 16.6 0.5 1.7 1 0 0 1 1 1 1 Bacterial membrane-spanning protein N-terminus Pterin_4a PF01329.19 CCC67822.1 - 5e-25 87.5 0.1 6.1e-25 87.2 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Adap_comp_sub PF00928.21 CCC67823.1 - 1e-69 234.9 2.0 1.6e-69 234.3 2.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Opi1 PF08618.10 CCC67824.1 - 8.2e-30 104.4 5.3 9.9e-22 77.8 1.2 3.2 1 1 1 2 2 2 2 Transcription factor Opi1 CLU PF13236.6 CCC67825.1 - 1.4e-61 208.1 0.0 3.5e-61 206.8 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 CCC67825.1 - 8.7e-34 117.1 0.1 5.8e-33 114.4 0.0 2.5 2 1 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.6 CCC67825.1 - 4.3e-20 71.9 0.8 4.3e-20 71.9 0.8 3.2 3 0 0 3 3 3 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.6 CCC67825.1 - 2.6e-07 30.8 0.0 0.0011 19.2 0.0 3.6 2 2 2 4 4 4 2 Tetratricopeptide repeat DUF727 PF05303.12 CCC67825.1 - 3.6e-07 30.2 0.4 1.8e-06 28.0 0.4 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_10 PF13374.6 CCC67825.1 - 3.3e-05 23.6 0.0 0.0062 16.4 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCC67825.1 - 0.02 14.7 0.0 5.3 7.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCC67825.1 - 0.037 14.2 0.1 0.72 10.2 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat CbiG_N PF11760.8 CCC67825.1 - 0.048 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Cobalamin synthesis G N-terminal Rad60-SLD PF11976.8 CCC67825.1 - 0.066 13.0 1.3 0.31 10.9 1.3 2.2 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like RE_MjaI PF09568.10 CCC67825.1 - 0.32 10.8 6.8 0.12 12.2 2.8 2.4 3 0 0 3 3 3 0 MjaI restriction endonuclease Fib_alpha PF08702.10 CCC67825.1 - 2 8.6 8.3 66 3.7 1.6 4.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Uteroglobin PF01099.17 CCC67825.1 - 2.5 8.5 4.7 1.5 9.2 1.2 2.5 2 0 0 2 2 2 0 Uteroglobin family BUD22 PF09073.10 CCC67827.1 - 2.3e-74 251.3 44.4 2.3e-74 251.3 44.4 2.2 2 1 0 2 2 2 1 BUD22 DUF5572 PF17733.1 CCC67827.1 - 7.5 6.5 9.6 3.5 7.6 0.1 4.0 4 0 0 4 4 4 0 Family of unknown function (DUF5572) p450 PF00067.22 CCC67828.1 - 9.8e-51 172.9 0.2 1.2e-50 172.6 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 KilA-N PF04383.13 CCC67829.1 - 0.0017 18.2 0.0 0.0017 18.2 0.0 4.0 4 1 0 4 4 4 2 KilA-N domain Fungal_trans PF04082.18 CCC67830.1 - 2.2e-21 76.1 11.4 2.2e-21 76.1 11.4 2.6 3 1 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC67830.1 - 8.2e-10 38.6 12.9 8.2e-10 38.6 12.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.24 CCC67831.1 - 2.1e-64 218.5 0.0 2.7e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CCC67831.1 - 4.1e-11 43.0 0.1 8.9e-11 41.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CCC67831.1 - 8e-06 25.3 0.0 0.00043 19.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCC67831.1 - 0.00018 20.9 1.9 0.0029 16.9 1.4 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CCC67831.1 - 0.00018 20.8 0.1 0.00041 19.7 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 CCC67831.1 - 0.00022 20.4 1.4 0.00031 19.9 1.4 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 CCC67831.1 - 0.00028 19.7 1.4 0.0076 15.0 0.8 2.2 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 CCC67831.1 - 0.0012 18.5 0.1 0.0039 16.8 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 CCC67831.1 - 0.0014 17.8 1.2 0.0019 17.3 0.7 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.17 CCC67831.1 - 0.0019 17.5 0.2 0.0035 16.6 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 CCC67831.1 - 0.012 16.1 1.9 0.22 12.1 0.4 2.7 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.20 CCC67831.1 - 0.013 15.6 0.1 0.024 14.7 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.7 CCC67831.1 - 0.014 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 CCC67831.1 - 0.024 13.9 0.1 0.045 13.0 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 CCC67831.1 - 0.21 10.6 0.2 0.55 9.2 0.4 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein UQ_con PF00179.26 CCC67832.1 - 1.1e-49 167.7 0.0 1.2e-49 167.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCC67832.1 - 0.13 11.9 0.0 0.16 11.6 0.0 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 CCC67832.1 - 0.26 11.6 1.1 0.4 11.0 0.5 1.8 1 1 1 2 2 2 0 RWD domain Glyco_hydro_76 PF03663.14 CCC67833.1 - 2.3e-159 530.8 26.6 2.7e-159 530.6 26.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 MnmE_helical PF12631.7 CCC67834.1 - 3.2e-40 138.5 5.2 4.2e-40 138.1 5.2 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 CCC67834.1 - 1.2e-35 122.3 0.0 2.4e-35 121.3 0.0 1.5 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 CCC67834.1 - 1.4e-24 86.3 0.3 3.3e-24 85.1 0.3 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCC67834.1 - 1.7e-12 47.1 1.0 3.8e-12 46.0 1.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CCC67834.1 - 2.1e-09 37.5 3.1 0.0004 20.3 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CCC67834.1 - 1.6e-06 27.8 0.2 0.00014 21.4 0.1 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.21 CCC67834.1 - 2.3e-06 27.2 2.2 3.5e-05 23.3 2.2 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 CCC67834.1 - 3e-06 27.4 3.1 0.00059 19.9 0.4 2.7 2 0 0 2 2 2 2 Dynamin family AIG1 PF04548.16 CCC67834.1 - 1.9e-05 24.1 0.9 4.2e-05 23.0 0.9 1.5 1 0 0 1 1 1 1 AIG1 family Ras PF00071.22 CCC67834.1 - 0.0002 21.0 0.0 0.0004 20.0 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC67834.1 - 0.00074 19.7 0.1 0.0065 16.7 0.1 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 CCC67834.1 - 0.0053 15.8 0.2 1.8 7.5 0.1 2.8 1 1 1 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB PduV-EutP PF10662.9 CCC67834.1 - 0.015 15.1 0.1 2.7 7.7 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 CCC67834.1 - 0.043 13.1 2.3 0.86 8.8 0.0 2.3 1 1 1 2 2 2 0 Septin UPF0231 PF06062.11 CCC67834.1 - 0.053 13.8 0.5 0.17 12.1 0.5 1.8 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) ABC_tran PF00005.27 CCC67834.1 - 0.068 13.7 1.5 0.19 12.2 1.5 1.9 1 1 0 1 1 1 0 ABC transporter DUF3800 PF12686.7 CCC67834.1 - 0.39 11.4 2.2 15 6.2 2.2 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) dsrm PF00035.26 CCC67835.1 - 3.9e-07 30.7 0.0 2.4e-06 28.1 0.0 2.1 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.26 CCC67835.1 - 7.6e-05 23.3 0.0 0.0002 21.9 0.0 1.8 1 0 0 1 1 1 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CCC67835.1 - 0.048 13.8 0.0 0.18 12.0 0.0 2.0 1 1 0 1 1 1 0 Ribonuclease-III-like Ribosomal_S15 PF00312.22 CCC67836.1 - 0.0017 18.5 0.2 0.0031 17.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 Desmo_N PF06771.11 CCC67836.1 - 0.0074 16.6 0.4 0.024 15.0 0.4 1.9 1 0 0 1 1 1 1 Viral Desmoplakin N-terminus MitMem_reg PF13012.6 CCC67836.1 - 0.0076 16.7 1.0 0.018 15.4 0.4 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function HBD PF18534.1 CCC67836.1 - 0.015 15.4 0.1 0.033 14.3 0.1 1.6 1 0 0 1 1 1 0 Helical bundle domain Pex2_Pex12 PF04757.14 CCC67837.1 - 1.9e-31 109.4 8.7 2.4e-31 109.1 8.7 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CCC67837.1 - 8.2e-06 25.6 3.5 1.3e-05 24.9 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCC67837.1 - 0.00026 20.8 5.4 0.0005 19.9 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCC67837.1 - 0.054 13.7 7.0 0.094 12.9 7.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Rad50_zn_hook PF04423.14 CCC67837.1 - 0.16 11.8 4.6 2 8.3 0.2 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-RING_2 PF13639.6 CCC67837.1 - 0.19 12.1 4.9 0.38 11.1 4.9 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 CCC67837.1 - 0.7 9.8 5.4 1.3 8.9 5.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC67837.1 - 9.7 6.3 7.4 19 5.4 7.4 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DUF89 PF01937.19 CCC67838.1 - 1.2e-110 369.9 4.4 1.3e-110 369.7 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 TAP42 PF04177.12 CCC67839.1 - 1.8e-86 290.2 17.5 2.1e-86 290.0 17.5 1.0 1 0 0 1 1 1 1 TAP42-like family Prismane PF03063.20 CCC67839.1 - 0.2 10.3 0.2 0.3 9.7 0.2 1.3 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF3888 PF13027.6 CCC67840.1 - 0.75 10.3 7.0 13 6.3 1.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3888) Striatin PF08232.12 CCC67841.1 - 7.1e-20 72.2 3.6 2.4e-19 70.5 1.2 2.4 1 1 1 2 2 2 1 Striatin family Jnk-SapK_ap_N PF09744.9 CCC67841.1 - 0.00084 19.6 2.1 0.0014 18.9 2.1 1.3 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 bPH_3 PF14470.6 CCC67841.1 - 0.033 14.5 0.9 0.16 12.3 0.2 2.5 2 0 0 2 2 2 0 Bacterial PH domain Mto2_bdg PF12808.7 CCC67841.1 - 0.24 11.7 2.3 0.46 10.8 2.3 1.4 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CUE PF02845.16 CCC67842.1 - 8.5e-05 22.2 0.1 0.00017 21.2 0.1 1.5 1 0 0 1 1 1 1 CUE domain PI3K_1B_p101 PF10486.9 CCC67842.1 - 8.2 4.1 35.3 14 3.3 35.3 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Frag1 PF10277.9 CCC67843.1 - 1.6e-79 266.5 18.4 1.9e-79 266.3 18.4 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF4079 PF13301.6 CCC67843.1 - 0.00041 20.5 2.0 0.0005 20.2 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4079) DUF872 PF05915.12 CCC67843.1 - 0.14 12.4 1.8 14 5.9 0.0 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Eisosome1 PF12757.7 CCC67844.1 - 1.5e-29 102.8 0.3 1.5e-29 102.8 0.3 4.8 3 1 0 3 3 3 1 Eisosome protein 1 FCH PF00611.23 CCC67845.1 - 1.8e-10 41.0 0.0 6.2e-10 39.2 0.0 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SBF_like PF13593.6 CCC67846.1 - 3.3e-119 397.9 15.3 3.8e-119 397.6 15.3 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 CCC67846.1 - 9.1e-13 48.3 9.3 9.1e-13 48.3 9.3 1.6 1 1 0 1 1 1 1 Sodium Bile acid symporter family Peptidase_S24 PF00717.23 CCC67847.1 - 1.5e-07 31.3 0.2 3.7e-07 30.0 0.1 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 CCC67847.1 - 0.00027 20.7 0.0 0.009 15.8 0.0 2.2 1 1 1 2 2 2 2 Signal peptidase, peptidase S26 Rhodanese PF00581.20 CCC67848.1 - 1.4e-13 51.2 0.0 4.1e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain DUF3417 PF11897.8 CCC67848.1 - 0.12 12.9 0.4 0.69 10.4 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3417) zf-C2H2 PF00096.26 CCC67849.1 - 3.7e-14 52.3 9.2 1.1e-06 28.8 2.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC67849.1 - 2.3e-08 34.2 9.0 0.002 18.8 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCC67849.1 - 2.9e-08 33.8 14.5 1.7e-07 31.3 2.4 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCC67849.1 - 3.4e-08 33.5 6.1 0.00049 20.3 0.7 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCC67849.1 - 3.5e-05 24.0 3.2 0.075 13.4 0.4 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.12 CCC67849.1 - 0.00011 22.4 3.0 0.00025 21.3 3.0 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CCC67849.1 - 0.0023 17.9 8.0 0.024 14.6 0.6 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger GAGA PF09237.11 CCC67849.1 - 0.028 14.2 2.0 0.11 12.3 0.9 2.5 1 1 1 2 2 2 0 GAGA factor zf-C2H2_9 PF16293.5 CCC67849.1 - 0.05 13.5 0.7 0.24 11.3 0.1 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-C2H2_3rep PF18868.1 CCC67849.1 - 0.053 14.2 0.6 0.053 14.2 0.6 4.5 3 2 0 3 3 2 0 Zinc finger C2H2-type, 3 repeats Zn-ribbon_8 PF09723.10 CCC67849.1 - 0.057 13.5 2.7 0.12 12.5 2.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zf-C2H2_2 PF12756.7 CCC67849.1 - 0.062 13.6 3.6 7.5 6.9 0.3 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf_UBZ PF18439.1 CCC67849.1 - 0.064 12.9 1.4 8.8 6.0 0.1 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 CCC67849.1 - 0.066 13.7 6.8 0.68 10.4 1.0 3.2 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 CCC67849.1 - 0.071 12.8 2.5 0.69 9.6 0.3 2.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_8 PF15909.5 CCC67849.1 - 0.072 13.4 1.8 0.31 11.4 1.8 2.1 1 0 0 1 1 1 0 C2H2-type zinc ribbon HypA PF01155.19 CCC67849.1 - 0.17 11.9 0.3 0.33 11.0 0.3 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-C2HC_2 PF13913.6 CCC67849.1 - 0.19 11.7 5.8 6.6 6.7 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-C2H2_11 PF16622.5 CCC67849.1 - 0.3 10.9 4.0 0.14 11.9 0.6 2.1 2 0 0 2 2 2 0 zinc-finger C2H2-type zf-H2C2_5 PF13909.6 CCC67849.1 - 0.48 10.2 8.9 1.4 8.7 0.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain DUF629 PF04780.12 CCC67849.1 - 0.48 8.9 5.0 2.9 6.3 0.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-BED PF02892.15 CCC67849.1 - 3.8 7.6 13.8 0.095 12.7 1.1 3.1 3 0 0 3 3 2 0 BED zinc finger Elf1 PF05129.13 CCC67849.1 - 8.9 6.4 7.0 3.3 7.8 0.9 2.6 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Sod_Cu PF00080.20 CCC67850.1 - 1.6e-07 31.6 0.0 1.1e-06 28.9 0.0 2.1 2 1 0 2 2 2 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.26 CCC67850.1 - 8.4e-07 29.4 0.0 2.1e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain PC4 PF02229.16 CCC67851.1 - 9.8e-22 76.3 0.1 2.1e-21 75.3 0.1 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF4551 PF15087.6 CCC67851.1 - 1.9 7.2 5.7 2 7.2 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Bap31 PF05529.12 CCC67852.1 - 1.7e-20 73.2 3.1 2.2e-20 72.9 3.1 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region DPM3 PF08285.11 CCC67852.1 - 0.011 15.9 3.3 0.016 15.4 0.2 2.4 1 1 1 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) UPF0220 PF05255.11 CCC67852.1 - 0.013 15.0 0.2 0.017 14.7 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0220) Saf_2TM PF18303.1 CCC67852.1 - 0.026 14.1 0.2 0.049 13.2 0.2 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain LMF1 PF06762.14 CCC67852.1 - 0.12 11.4 0.7 0.12 11.4 0.7 1.1 1 0 0 1 1 1 0 Lipase maturation factor Wzy_C PF04932.15 CCC67852.1 - 1.2 8.8 5.4 0.24 11.0 0.9 1.8 1 1 1 2 2 2 0 O-Antigen ligase Aldo_ket_red PF00248.21 CCC67853.1 - 3.1e-51 174.3 0.0 3.6e-51 174.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SRF-TF PF00319.18 CCC67854.1 - 1.3e-20 72.6 0.0 2e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.14 CCC67854.1 - 0.48 8.6 4.0 0.54 8.5 4.0 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 CCC67854.1 - 0.52 9.7 10.5 0.59 9.5 10.5 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 CCC67854.1 - 0.91 7.7 10.9 0.97 7.6 10.9 1.0 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.10 CCC67854.1 - 6.8 5.9 10.5 7.9 5.7 10.5 1.1 1 0 0 1 1 1 0 BUD22 SRF-TF PF00319.18 CCC67855.1 - 4.7e-21 74.0 0.2 7.5e-21 73.4 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PWWP PF00855.17 CCC67856.1 - 4.1e-23 81.6 0.1 1.7e-22 79.6 0.1 2.2 1 1 0 1 1 1 1 PWWP domain DUF4778 PF16008.5 CCC67856.1 - 1.3 9.0 8.6 2.2 8.2 8.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) eIF-5a PF01287.20 CCC67857.1 - 2.5e-29 101.2 0.5 3.4e-29 100.7 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CCC67857.1 - 0.01 15.8 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Cytochrom_C PF00034.21 CCC67858.1 - 1.1e-11 45.7 0.5 2e-11 44.9 0.5 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CCC67858.1 - 6.5e-08 32.8 3.0 5.7e-07 29.8 3.0 1.9 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CCC67858.1 - 0.21 11.3 1.0 0.59 9.8 0.1 2.0 2 1 0 2 2 2 0 Cytochrome c-550 domain NAD_kinase PF01513.21 CCC67859.1 - 2.5e-89 299.4 0.1 1.5e-88 296.8 0.0 1.9 2 0 0 2 2 2 1 ATP-NAD kinase DAGK_cat PF00781.24 CCC67859.1 - 0.015 14.9 0.0 0.051 13.2 0.0 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Isy1 PF06246.12 CCC67860.1 - 1.4e-52 178.8 16.6 5.7e-51 173.5 16.6 2.0 1 1 0 1 1 1 1 Isy1-like splicing family SHNi-TPR PF10516.9 CCC67860.1 - 0.038 13.4 0.1 0.095 12.2 0.1 1.7 1 0 0 1 1 1 0 SHNi-TPR Porin_4 PF13609.6 CCC67860.1 - 0.078 12.7 0.0 0.084 12.6 0.0 1.2 1 0 0 1 1 1 0 Gram-negative porin Beta_elim_lyase PF01212.21 CCC67861.1 - 7e-78 261.9 0.0 8.5e-78 261.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase FAD_binding_2 PF00890.24 CCC67862.1 - 6.4e-70 236.3 0.0 7.4e-70 236.1 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 CCC67862.1 - 1.5e-06 28.4 0.3 5.8e-06 26.4 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 CCC67862.1 - 2.8e-06 27.2 0.1 7.4e-05 22.5 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CCC67862.1 - 8.8e-06 25.1 4.1 4.2e-05 22.9 1.9 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCC67862.1 - 1.1e-05 24.8 0.2 0.00091 18.5 0.0 2.3 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.14 CCC67862.1 - 0.00069 18.4 2.7 0.04 12.6 0.1 3.1 3 0 0 3 3 3 1 HI0933-like protein Lycopene_cycl PF05834.12 CCC67862.1 - 0.00097 18.3 0.0 0.055 12.5 0.1 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 CCC67862.1 - 0.007 15.5 2.4 0.014 14.5 0.0 2.6 4 0 0 4 4 4 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CCC67862.1 - 0.02 14.1 0.3 0.038 13.2 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain TPP_enzyme_M PF00205.22 CCC67862.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Pyr_redox PF00070.27 CCC67862.1 - 0.14 12.7 0.8 17 6.0 0.1 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase LRR_6 PF13516.6 CCC67863.1 - 0.0017 18.2 10.1 5.3 7.4 0.0 6.6 6 0 0 6 6 6 2 Leucine Rich repeat LRR_4 PF12799.7 CCC67863.1 - 0.021 15.2 3.7 0.021 15.2 3.7 6.5 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) Tugs PF17840.1 CCC67863.1 - 0.39 10.9 1.8 17 5.7 0.1 3.0 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain AvrB_AvrC PF05394.11 CCC67864.1 - 0.021 14.1 3.1 0.022 13.9 0.8 2.0 2 0 0 2 2 2 0 Avirulence protein KCH PF16944.5 CCC67865.1 - 6.5e-94 314.4 18.8 8.6e-94 314.0 18.8 1.2 1 0 0 1 1 1 1 Fungal potassium channel DUF996 PF06195.13 CCC67865.1 - 2 8.7 8.2 1.2 9.4 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Hit1_C PF18268.1 CCC67866.1 - 1.1e-42 144.0 2.1 1.6e-42 143.5 2.1 1.3 1 0 0 1 1 1 1 Hit1 C-terminal zf-HIT PF04438.16 CCC67866.1 - 6.1e-11 42.0 12.0 6.1e-11 42.0 12.0 2.0 2 0 0 2 2 2 1 HIT zinc finger YL1_C PF08265.11 CCC67866.1 - 0.0008 19.1 0.0 0.002 17.8 0.0 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-C6H2 PF15801.5 CCC67866.1 - 0.042 14.2 7.9 0.042 14.2 7.9 1.9 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zf-Mss51 PF13824.6 CCC67866.1 - 0.042 13.9 5.1 0.096 12.8 5.1 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-B_box PF00643.24 CCC67866.1 - 0.065 13.4 11.4 1 9.6 6.6 2.2 2 0 0 2 2 2 0 B-box zinc finger zf-MYND PF01753.18 CCC67866.1 - 0.67 10.1 12.6 0.16 12.1 8.6 1.9 2 0 0 2 2 2 0 MYND finger GFO_IDH_MocA PF01408.22 CCC67867.1 - 4.1e-09 37.3 0.0 6.5e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CCC67867.1 - 0.00066 19.7 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF4588 PF15251.6 CCC67868.1 - 2.3e-07 30.8 1.3 6.3e-07 29.4 1.3 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) DUF713 PF05218.14 CCC67868.1 - 0.00086 19.1 0.1 0.0019 18.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF713) Laminin_II PF06009.12 CCC67869.1 - 0.0016 18.4 1.7 0.0019 18.2 1.7 1.1 1 0 0 1 1 1 1 Laminin Domain II Prefoldin_2 PF01920.20 CCC67869.1 - 0.0035 17.3 5.1 0.0045 16.9 5.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF948 PF06103.11 CCC67869.1 - 0.0054 17.0 1.5 0.0062 16.8 1.5 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) FTO_CTD PF12934.7 CCC67869.1 - 0.006 16.4 1.9 0.0077 16.0 1.9 1.1 1 0 0 1 1 1 1 FTO C-terminal domain CLZ PF16526.5 CCC67869.1 - 0.0082 16.5 3.3 0.01 16.1 3.3 1.2 1 0 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels bZIP_1 PF00170.21 CCC67869.1 - 0.017 15.2 6.5 0.025 14.7 6.5 1.2 1 0 0 1 1 1 0 bZIP transcription factor DMPK_coil PF08826.10 CCC67869.1 - 0.031 14.4 5.9 0.05 13.7 5.8 1.5 1 1 0 1 1 1 0 DMPK coiled coil domain like OmpH PF03938.14 CCC67869.1 - 0.051 13.9 5.5 0.054 13.8 5.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Viral_P18 PF04521.13 CCC67869.1 - 0.072 12.9 0.2 0.081 12.7 0.2 1.1 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein bZIP_2 PF07716.15 CCC67869.1 - 0.082 13.0 7.2 0.12 12.4 7.2 1.2 1 0 0 1 1 1 0 Basic region leucine zipper FlaC_arch PF05377.11 CCC67869.1 - 0.13 12.7 6.1 0.18 12.3 5.8 1.4 1 1 0 1 1 1 0 Flagella accessory protein C (FlaC) DASH_Dam1 PF08653.10 CCC67869.1 - 0.13 12.1 1.2 0.2 11.5 1.2 1.4 1 0 0 1 1 1 0 DASH complex subunit Dam1 Spc24 PF08286.11 CCC67869.1 - 0.57 10.5 7.1 0.69 10.2 7.1 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Syja_N PF02383.18 CCC67870.1 - 1.5e-45 155.9 0.5 2.4e-45 155.2 0.5 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CCC67870.1 - 3.9e-11 42.9 0.0 5.7e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Use1 PF09753.9 CCC67871.1 - 1.8e-06 27.9 0.1 2.1e-06 27.7 0.1 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 DUF16 PF01519.16 CCC67871.1 - 0.022 15.2 0.0 0.028 14.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 Retrotran_gag_2 PF14223.6 CCC67871.1 - 0.029 14.0 0.2 0.039 13.6 0.2 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF5595 PF18077.1 CCC67871.1 - 0.12 12.5 0.1 11 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) Synaptobrevin PF00957.21 CCC67871.1 - 0.53 10.1 6.4 1.3 8.8 6.4 1.7 1 1 0 1 1 1 0 Synaptobrevin Thioredoxin PF00085.20 CCC67872.1 - 3.4e-27 94.4 1.8 3.6e-21 75.1 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 CCC67872.1 - 6.8e-06 26.1 0.2 3.4e-05 23.8 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CCC67872.1 - 0.00063 19.2 2.0 0.28 10.5 0.0 4.2 2 2 2 4 4 4 1 OST3 / OST6 family, transporter family DUF2847 PF11009.8 CCC67872.1 - 0.11 12.4 1.8 0.74 9.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) Mito_carr PF00153.27 CCC67873.1 - 1.7e-70 233.0 0.3 4.5e-23 81.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCC67873.1 - 0.02 14.1 0.2 0.39 9.8 0.0 2.9 2 2 1 4 4 4 0 Gammaproteobacterial serine protease Gti1_Pac2 PF09729.9 CCC67874.1 - 7.4e-49 166.3 0.0 2.1e-47 161.5 0.0 2.4 1 1 0 1 1 1 1 Gti1/Pac2 family Nas2_N PF18265.1 CCC67875.1 - 1.6e-23 82.4 0.7 1.6e-23 82.4 0.7 1.9 2 0 0 2 2 2 1 Nas2 N_terminal domain PDZ PF00595.24 CCC67875.1 - 4.1e-05 23.8 0.6 9.8e-05 22.6 0.3 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 CCC67875.1 - 0.00087 19.6 0.2 0.0023 18.2 0.0 1.8 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 CCC67875.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 PDZ domain GRASP55_65 PF04495.14 CCC67875.1 - 0.072 13.4 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain CAP_GLY PF01302.25 CCC67876.1 - 5.8e-15 55.1 0.1 9.4e-15 54.4 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 CCC67876.1 - 2.7e-14 52.7 9.1 0.0058 16.4 0.2 5.7 3 2 1 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 CCC67876.1 - 3.8e-12 46.2 20.6 0.0033 17.8 0.1 6.3 3 1 1 5 5 5 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CCC67876.1 - 1.6e-06 27.7 11.5 6.8 7.0 0.1 8.2 9 0 0 9 9 9 3 Leucine Rich repeat LRR_1 PF00560.33 CCC67876.1 - 0.00067 19.8 17.8 5.5 7.9 0.2 8.5 7 2 1 8 8 8 2 Leucine Rich Repeat ResIII PF04851.15 CCC67877.1 - 3e-20 72.9 0.6 1.3e-19 70.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCC67877.1 - 2e-19 70.0 1.7 1.2e-18 67.5 0.2 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCC67877.1 - 1.1e-17 64.3 0.0 5.7e-17 62.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 CCC67877.1 - 7.6e-06 24.9 3.4 2.9e-05 22.9 0.1 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain PHP PF02811.19 CCC67877.1 - 0.011 16.0 0.1 0.028 14.7 0.1 1.7 1 1 0 1 1 1 0 PHP domain DXP_reductoisom PF02670.16 CCC67877.1 - 0.2 12.4 1.1 0.56 10.9 0.1 2.3 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Aim21 PF11489.8 CCC67878.1 - 1.3e-20 74.0 3.1 1.3e-20 74.0 3.1 3.7 3 1 1 4 4 4 2 Altered inheritance of mitochondria protein 21 GvpK PF05121.12 CCC67878.1 - 0.2 11.7 3.9 1 9.5 3.9 2.2 1 0 0 1 1 1 0 Gas vesicle protein K DnaJ-X PF14308.6 CCC67879.1 - 9.3e-77 257.2 1.5 9.3e-77 257.2 1.5 2.3 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CCC67879.1 - 4.3e-24 84.4 0.8 1.2e-23 83.0 0.8 1.8 1 0 0 1 1 1 1 DnaJ domain Presenilin PF01080.17 CCC67879.1 - 0.65 8.7 6.2 1 8.0 6.2 1.3 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 CCC67880.1 - 9.9e-18 63.7 0.0 1.8e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC67880.1 - 0.0054 16.8 0.0 0.012 15.7 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif EF-hand_4 PF12763.7 CCC67881.1 - 2.6e-25 88.4 0.0 1.4e-13 50.7 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CCC67881.1 - 3.4e-07 30.6 0.0 3.5e-05 24.2 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 CCC67881.1 - 0.00012 21.4 0.0 0.0077 15.7 0.0 3.1 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 CCC67881.1 - 0.0049 16.7 0.0 0.37 10.8 0.0 3.4 4 0 0 4 4 4 1 EF-hand domain DUF1720 PF08226.11 CCC67881.1 - 0.034 14.5 150.3 0.022 15.2 14.9 9.7 2 2 3 5 5 5 0 Domain of unknown function (DUF1720) DUF826 PF05696.11 CCC67881.1 - 0.17 12.0 0.6 1.6 8.9 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF826) Peptidase_C48 PF02902.19 CCC67882.1 - 6.3e-35 121.0 2.5 6.3e-35 121.0 2.5 2.6 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain GIDA_assoc PF13932.6 CCC67882.1 - 8.4 6.5 12.8 0.36 11.0 4.9 2.6 3 0 0 3 3 3 0 GidA associated domain RINGv PF12906.7 CCC67883.1 - 8.1e-14 51.5 7.0 1.6e-13 50.6 7.0 1.5 1 0 0 1 1 1 1 RING-variant domain MMgT PF10270.9 CCC67884.1 - 4.3e-26 91.2 0.0 5.5e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter AMPK1_CBM PF16561.5 CCC67885.1 - 5.6e-06 26.5 0.5 1.2e-05 25.5 0.5 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Zip PF02535.22 CCC67886.1 - 5e-50 170.6 20.8 1.2e-38 133.2 7.1 3.0 2 1 1 3 3 3 3 ZIP Zinc transporter Polysacc_synt_C PF14667.6 CCC67886.1 - 4.9 7.2 9.8 3.2 7.8 2.2 3.0 4 0 0 4 4 4 0 Polysaccharide biosynthesis C-terminal domain cNMP_binding PF00027.29 CCC67887.1 - 2.9e-44 149.1 0.0 7.7e-22 77.2 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.11 CCC67887.1 - 0.03 14.0 2.9 0.79 9.5 0.3 2.7 2 1 0 2 2 2 0 Cupin domain Ribosomal_L27 PF01016.19 CCC67887.1 - 0.17 11.9 0.2 0.55 10.3 0.1 1.9 2 1 0 2 2 2 0 Ribosomal L27 protein F_actin_cap_B PF01115.17 CCC67888.1 - 2.6e-96 321.9 0.5 3e-96 321.7 0.5 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Aminotran_5 PF00266.19 CCC67889.1 - 4.6e-16 58.7 0.0 5.4e-16 58.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CCC67889.1 - 6e-06 25.7 0.1 8.9e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CCC67889.1 - 0.00037 19.9 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CCC67889.1 - 0.0076 15.0 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain SHMT PF00464.19 CCC67889.1 - 0.12 11.0 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Pkinase PF00069.25 CCC67890.1 - 8.9e-57 192.4 4.7 4.5e-50 170.5 0.9 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67890.1 - 4.9e-17 62.1 0.4 6.3e-13 48.6 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 CCC67890.1 - 2.7e-05 24.2 0.1 8.1e-05 22.7 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCC67890.1 - 0.0086 14.9 0.0 0.015 14.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 CCC67890.1 - 0.014 15.0 0.2 0.037 13.6 0.2 1.8 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.14 CCC67890.1 - 0.03 13.7 0.3 0.062 12.6 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF496 PF04363.12 CCC67890.1 - 1.4 9.0 6.4 0.78 9.8 0.6 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF496) bZIP_1 PF00170.21 CCC67891.1 - 2.2e-13 50.1 10.3 6.8e-13 48.5 10.3 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CCC67891.1 - 1.5e-05 24.9 9.4 1.5e-05 24.9 9.4 2.1 2 0 0 2 2 2 1 Basic region leucine zipper Curto_V2 PF07325.11 CCC67891.1 - 0.31 10.9 1.6 0.58 10.0 1.6 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein DUF3622 PF12286.8 CCC67892.1 - 0.097 13.0 0.0 0.32 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3622) Not3 PF04065.15 CCC67893.1 - 3.6e-79 265.4 29.0 3.6e-79 265.4 29.0 2.5 1 1 1 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 CCC67893.1 - 2.2e-21 76.3 2.4 3.1e-21 75.8 0.2 2.4 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Syntaxin_2 PF14523.6 CCC67893.1 - 0.0099 16.2 2.6 0.0099 16.2 2.6 3.3 3 0 0 3 3 3 1 Syntaxin-like protein Apq12 PF12716.7 CCC67895.1 - 0.0021 18.0 9.3 0.0021 18.0 9.3 1.8 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis DUF4388 PF14332.6 CCC67895.1 - 0.14 12.5 0.1 0.32 11.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4388) BAR_2 PF10455.9 CCC67896.1 - 3.4e-77 259.4 19.3 3.4e-77 259.4 19.3 1.7 1 1 1 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CCC67896.1 - 4.6e-09 36.3 14.7 5.6e-08 32.7 14.0 2.5 1 1 0 1 1 1 1 BAR domain DUF1664 PF07889.12 CCC67896.1 - 0.067 13.2 0.2 0.067 13.2 0.2 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) DASH_Dad2 PF08654.10 CCC67896.1 - 0.39 11.2 14.1 1.4 9.4 0.5 3.9 1 1 3 4 4 4 0 DASH complex subunit Dad2 BCDHK_Adom3 PF10436.9 CCC67897.1 - 7e-26 91.0 1.4 1.1e-25 90.4 1.4 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CCC67897.1 - 2.7e-14 53.6 0.1 1e-11 45.3 0.1 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CCC67897.1 - 0.00021 21.1 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.6 CCC67897.1 - 0.00044 20.2 0.0 0.00077 19.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-like ATPase domain NAD_binding_1 PF00175.21 CCC67898.1 - 1.4e-30 106.1 0.1 3.3e-30 105.0 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 CCC67898.1 - 2.2e-29 101.7 0.0 3.4e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 CCC67898.1 - 0.0021 18.2 0.0 0.15 12.2 0.0 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 CCC67898.1 - 0.013 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain ArfGap PF01412.18 CCC67899.1 - 4e-37 126.8 0.1 4e-37 126.8 0.1 2.5 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf CBM_21 PF03370.13 CCC67900.1 - 5.6e-27 94.2 8.1 5.6e-27 94.2 8.1 2.1 2 1 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CCC67900.1 - 5.9e-10 39.6 4.0 5.9e-10 39.6 4.0 2.4 2 0 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) WD40 PF00400.32 CCC67901.1 - 5.8e-36 121.9 24.4 2.6e-06 28.1 0.3 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat F-box-like PF12937.7 CCC67901.1 - 3.4e-13 49.3 1.8 6.6e-13 48.3 1.8 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 CCC67901.1 - 2.2e-12 46.4 7.8 0.005 15.5 0.1 5.5 3 2 3 6 6 6 4 Nucleoporin Nup120/160 F-box PF00646.33 CCC67901.1 - 1.6e-10 40.6 1.1 3.6e-10 39.5 1.1 1.7 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 CCC67901.1 - 1e-06 29.0 0.4 3.2 8.1 0.0 5.6 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCC67901.1 - 8.4e-05 22.0 0.3 0.18 11.1 0.1 3.3 2 1 1 3 3 3 1 WD40-like domain eIF2A PF08662.11 CCC67901.1 - 0.038 13.9 0.4 9.3 6.1 0.0 3.1 2 2 2 4 4 4 0 Eukaryotic translation initiation factor eIF2A PAN_4 PF14295.6 CCC67901.1 - 0.063 13.2 0.4 0.063 13.2 0.4 2.2 2 0 0 2 2 2 0 PAN domain EXS PF03124.14 CCC67902.1 - 8.8e-85 284.9 24.9 1.5e-84 284.1 24.9 1.4 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CCC67902.1 - 7.9e-36 124.8 21.6 2.8e-34 119.7 19.0 2.4 2 1 0 2 2 2 1 SPX domain PhoLip_ATPase_C PF16212.5 CCC67903.1 - 7.3e-49 166.8 13.1 7.3e-49 166.8 13.1 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCC67903.1 - 1.2e-18 66.6 0.6 3.5e-18 65.0 0.6 1.9 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CCC67903.1 - 4.9e-13 49.0 0.0 1.1e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 CCC67903.1 - 1.8e-12 48.0 0.2 2.7e-07 31.1 0.1 2.9 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCC67903.1 - 2e-10 40.6 0.0 2.8e-09 36.9 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCC67903.1 - 0.0084 15.9 0.1 0.041 13.6 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1634 PF07843.11 CCC67903.1 - 2.6 8.2 6.4 6.3 6.9 0.9 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1634) Steroid_dh PF02544.16 CCC67904.1 - 2.6e-06 27.5 8.6 2.6e-06 27.5 8.6 1.9 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Transp_cyt_pur PF02133.15 CCC67905.1 - 4.1e-94 315.8 43.9 4.8e-94 315.6 43.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin CAAD PF14159.6 CCC67905.1 - 3 7.8 8.5 0.064 13.1 1.0 2.2 2 0 0 2 2 2 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Cyclin PF08613.11 CCC67906.1 - 6.1e-49 166.5 1.9 6.1e-49 166.5 1.9 2.8 2 2 0 2 2 2 1 Cyclin Ntox17 PF15524.6 CCC67906.1 - 0.013 15.8 0.1 0.034 14.4 0.1 1.8 1 0 0 1 1 1 0 Novel toxin 17 Gag_p10 PF02337.17 CCC67906.1 - 0.15 12.0 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral GAG p10 protein LicD PF04991.13 CCC67906.1 - 1.8 8.6 10.7 1.2 9.2 8.4 1.9 2 1 0 2 2 2 0 LicD family Ribonuc_L-PSP PF01042.21 CCC67907.1 - 1.6e-42 144.3 0.5 1.9e-42 144.1 0.5 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peptidase_S13 PF02113.15 CCC67907.1 - 0.091 11.5 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Ribosomal_L34e PF01199.18 CCC67908.1 - 3.2e-42 142.7 3.6 3.2e-42 142.7 3.6 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 CCC67908.1 - 0.1 12.0 1.9 0.11 11.9 0.1 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain HAD_2 PF13419.6 CCC67909.1 - 1.9e-15 57.4 0.0 2.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCC67909.1 - 1.7e-08 35.0 0.0 1e-06 29.2 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCC67909.1 - 0.00052 20.0 0.0 0.00087 19.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 CCC67909.1 - 0.031 14.7 0.0 0.041 14.3 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Tho1_MOS11_C PF18592.1 CCC67910.1 - 4.5e-27 93.6 1.1 9.3e-27 92.6 1.1 1.6 1 0 0 1 1 1 1 Tho1/MOS11 C-terminal domain SAP PF02037.27 CCC67910.1 - 1e-11 44.3 1.5 2.3e-11 43.2 1.5 1.6 1 0 0 1 1 1 1 SAP domain DUF4355 PF14265.6 CCC67910.1 - 0.18 12.1 11.1 0.2 11.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) GET2 PF08690.10 CCC67910.1 - 2.6 7.6 7.5 3.5 7.2 7.5 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Vhr1 PF04001.13 CCC67912.1 - 2.1e-44 149.8 2.1 4.5e-44 148.7 2.1 1.6 1 0 0 1 1 1 1 Transcription factor Vhr1 RGI1 PF10843.8 CCC67913.1 - 8.2e-35 120.2 10.5 1.4e-34 119.4 10.5 1.3 1 1 0 1 1 1 1 Respiratory growth induced protein 1 DIX PF00778.17 CCC67913.1 - 0.078 12.8 2.8 0.23 11.3 0.2 2.3 2 0 0 2 2 2 0 DIX domain Ran_BP1 PF00638.18 CCC67914.1 - 2.9e-33 114.7 0.0 7.3e-33 113.4 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CCC67914.1 - 0.013 15.4 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 WH1 domain Methyltransf_31 PF13847.6 CCC67915.1 - 2.5e-27 95.6 0.1 3.9e-27 94.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCC67915.1 - 3.5e-11 43.6 0.0 8.4e-11 42.4 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC67915.1 - 4.4e-09 36.9 0.0 8.9e-09 35.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC67915.1 - 4.2e-08 33.8 0.1 8.2e-08 32.9 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CCC67915.1 - 2.2e-07 31.0 0.0 2.8e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCC67915.1 - 6.5e-07 29.3 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 CCC67915.1 - 3.7e-06 26.6 0.0 5.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 CCC67915.1 - 0.00012 22.0 0.0 0.00022 21.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.8 CCC67915.1 - 0.0017 17.6 0.1 0.0047 16.1 0.1 1.6 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_4 PF02390.17 CCC67915.1 - 0.0091 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 CCC67915.1 - 0.021 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.13 CCC67915.1 - 0.044 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Fis1_TPR_C PF14853.6 CCC67916.1 - 2.9e-25 88.1 0.5 2.9e-25 88.1 0.5 1.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 CCC67916.1 - 1.3e-16 59.9 0.1 2.1e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.6 CCC67916.1 - 0.0043 17.5 0.0 0.0078 16.7 0.0 1.5 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCC67916.1 - 0.031 14.4 0.1 0.057 13.5 0.1 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat ETRAMP PF09716.10 CCC67916.1 - 0.091 12.8 1.6 0.14 12.2 1.7 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ribonuc_red_lgC PF02867.15 CCC67917.1 - 9.7e-185 615.0 0.0 1.2e-184 614.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CCC67917.1 - 5.4e-24 84.0 0.0 1.4e-23 82.7 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CCC67917.1 - 2.1e-18 66.6 0.0 9.8e-18 64.5 0.0 2.3 2 0 0 2 2 2 1 ATP cone domain Baculo_F PF12259.8 CCC67917.1 - 0.064 11.8 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Baculovirus F protein LCCL PF03815.19 CCC67918.1 - 5e-06 26.5 0.0 8.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Ribosomal_S24e PF01282.19 CCC67919.1 - 9.5e-35 118.4 0.2 1.6e-34 117.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Y_phosphatase PF00102.27 CCC67920.1 - 5.1e-48 163.7 0.6 5.1e-48 163.7 0.6 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 CCC67920.1 - 0.0029 17.4 4.0 0.027 14.3 0.0 3.0 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CCC67920.1 - 0.075 13.0 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family MAM33 PF02330.16 CCC67921.1 - 1.2e-63 214.9 8.4 1.4e-63 214.7 8.4 1.0 1 0 0 1 1 1 1 Mitochondrial glycoprotein Rota_NSP3 PF01665.16 CCC67921.1 - 0.00019 20.7 0.0 0.00038 19.7 0.0 1.6 1 1 0 1 1 1 1 Rotavirus non-structural protein NSP3 CH PF00307.31 CCC67922.1 - 0.055 13.7 1.6 76 3.5 0.0 4.1 3 1 1 4 4 4 0 Calponin homology (CH) domain PCI PF01399.27 CCC67922.1 - 0.098 13.2 0.6 0.24 11.9 0.2 1.9 2 0 0 2 2 2 0 PCI domain HORMA PF02301.18 CCC67923.1 - 3.2e-58 196.8 0.3 5.5e-58 196.0 0.3 1.4 1 0 0 1 1 1 1 HORMA domain PHD_2 PF13831.6 CCC67923.1 - 0.23 11.1 5.9 0.92 9.1 6.0 2.0 1 1 0 1 1 1 0 PHD-finger SPO22 PF08631.10 CCC67925.1 - 6.8e-70 235.7 17.3 1.8e-67 227.7 7.0 3.6 3 1 0 3 3 3 2 Meiosis protein SPO22/ZIP4 like BATS PF06968.13 CCC67925.1 - 0.033 14.3 0.0 1.2 9.4 0.0 2.6 2 0 0 2 2 2 0 Biotin and Thiamin Synthesis associated domain Atypical_Card PF18461.1 CCC67925.1 - 0.08 13.2 1.4 2.1 8.6 0.0 3.8 3 1 1 4 4 4 0 Atypical caspase recruitment domain TPR_2 PF07719.17 CCC67925.1 - 1 9.6 3.0 2.5 8.4 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat E1_UFD PF09358.10 CCC67925.1 - 1.4 9.6 6.6 26 5.6 0.1 4.3 4 1 0 4 4 4 0 Ubiquitin fold domain 2-Hacid_dh_C PF02826.19 CCC67926.1 - 6.6e-53 178.7 0.0 1.2e-52 177.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCC67926.1 - 8.1e-38 129.1 0.1 1.4e-37 128.4 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CCC67926.1 - 4.1e-05 23.8 0.1 0.0001 22.5 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 CCC67926.1 - 0.0007 20.1 0.1 0.0018 18.8 0.0 1.7 2 0 0 2 2 2 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.21 CCC67926.1 - 0.047 13.8 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Coatomer_E PF04733.14 CCC67927.1 - 3.5e-06 26.6 13.2 6.3e-06 25.8 13.2 1.4 1 1 0 1 1 1 1 Coatomer epsilon subunit CagE_TrbE_VirB PF03135.14 CCC67927.1 - 0.0015 18.7 3.1 0.0025 17.9 3.1 1.4 1 0 0 1 1 1 1 CagE, TrbE, VirB family, component of type IV transporter system ANAPC5 PF12862.7 CCC67927.1 - 0.039 14.0 0.9 0.066 13.3 0.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 DUF1689 PF07954.11 CCC67928.1 - 1.4e-57 194.2 0.8 2.2e-57 193.6 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) tRNA-synt_2b PF00587.25 CCC67929.1 - 9.7e-37 126.7 0.0 1.8e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 CCC67929.1 - 6.4e-22 77.5 1.2 1.5e-21 76.3 1.2 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 CCC67929.1 - 1.6e-14 53.7 0.0 3.5e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 CCC67929.1 - 4.5e-13 49.1 0.0 8.8e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain HEPN_AbiV PF18728.1 CCC67929.1 - 0.12 12.5 1.0 5.3 7.2 0.5 2.5 2 0 0 2 2 2 0 AbiV zf-CCHC PF00098.23 CCC67930.1 - 2.6e-14 52.5 37.1 1.7e-05 24.6 2.1 4.8 4 1 0 4 4 4 3 Zinc knuckle zf-CCHC_2 PF13696.6 CCC67930.1 - 0.001 18.8 41.7 0.0015 18.3 2.4 5.3 5 0 0 5 5 5 3 Zinc knuckle zf-C2H2_10 PF16588.5 CCC67930.1 - 0.0022 17.7 1.7 0.0022 17.7 1.7 4.5 4 1 1 5 5 5 1 C2H2 zinc-finger zf-CCHC_4 PF14392.6 CCC67930.1 - 0.015 15.0 0.4 0.015 15.0 0.4 5.0 4 1 1 5 5 5 0 Zinc knuckle Elongin_A PF06881.11 CCC67930.1 - 0.14 12.7 0.1 0.14 12.7 0.1 2.3 2 1 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CDC45 PF02724.14 CCC67930.1 - 0.49 8.6 10.7 2 6.6 11.4 1.5 2 0 0 2 2 2 0 CDC45-like protein zf-CCHC_3 PF13917.6 CCC67930.1 - 8.8 6.4 22.8 15 5.7 0.0 4.0 2 1 1 3 3 3 0 Zinc knuckle Pmp3 PF01679.17 CCC67931.1 - 9.3e-22 77.0 4.8 1.3e-21 76.5 4.8 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Aldo_ket_red PF00248.21 CCC67932.1 - 1.7e-41 142.4 0.0 4.5e-41 141.0 0.0 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_10 PF00331.20 CCC67932.1 - 0.055 12.6 0.1 4.2 6.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 HIT PF01230.23 CCC67933.1 - 3.3e-25 88.7 0.1 4.3e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CCC67933.1 - 3.7e-10 40.3 0.2 5.4e-10 39.7 0.2 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CCC67933.1 - 0.011 15.6 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 AAA PF00004.29 CCC67934.1 - 4.3e-99 328.1 0.0 2.8e-48 163.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC67934.1 - 5.3e-25 86.9 5.9 5.4e-14 51.7 0.8 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 CCC67934.1 - 5.8e-18 64.8 0.2 1.6e-17 63.4 0.2 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.14 CCC67934.1 - 1.6e-14 54.4 0.0 6e-07 29.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCC67934.1 - 7e-14 51.9 0.0 1.5e-05 24.8 0.0 2.9 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCC67934.1 - 6.2e-13 49.5 0.3 9.9e-05 22.8 0.0 4.5 3 2 0 3 3 2 2 AAA ATPase domain AAA_5 PF07728.14 CCC67934.1 - 2.9e-11 43.5 0.8 9.8e-06 25.6 0.1 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 CCC67934.1 - 3.2e-11 43.6 0.0 1.1e-05 25.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CCC67934.1 - 3.3e-09 36.4 0.0 0.0015 17.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 CCC67934.1 - 7.3e-09 36.0 1.1 0.078 13.3 0.0 4.3 2 2 2 4 4 4 2 AAA domain CDC48_2 PF02933.17 CCC67934.1 - 3.6e-08 33.1 0.0 9.2e-08 31.8 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 CCC67934.1 - 1e-07 32.0 0.0 0.024 14.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 CCC67934.1 - 2e-07 31.4 0.0 0.0082 16.5 0.0 3.0 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 CCC67934.1 - 5.5e-07 29.2 0.5 0.037 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.10 CCC67934.1 - 5.8e-07 29.4 0.1 4.3e-05 23.4 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain IstB_IS21 PF01695.17 CCC67934.1 - 1.2e-06 28.4 0.0 0.032 14.0 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein ATPase PF06745.13 CCC67934.1 - 1.3e-06 28.0 1.1 0.29 10.5 0.0 3.7 2 1 0 3 3 3 2 KaiC AAA_18 PF13238.6 CCC67934.1 - 4.8e-06 27.2 0.0 0.14 12.7 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CCC67934.1 - 8e-06 25.7 0.0 0.088 12.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_7 PF12775.7 CCC67934.1 - 8.6e-06 25.4 0.1 0.07 12.6 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_25 PF13481.6 CCC67934.1 - 1.1e-05 25.1 7.5 0.66 9.5 0.1 4.5 2 2 2 4 4 4 1 AAA domain Bac_DnaA PF00308.18 CCC67934.1 - 1.7e-05 24.8 0.0 0.032 14.1 0.0 2.9 3 0 0 3 3 2 1 Bacterial dnaA protein Sigma54_activat PF00158.26 CCC67934.1 - 1.9e-05 24.4 0.0 0.2 11.3 0.0 3.4 2 1 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CCC67934.1 - 3.4e-05 23.1 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 PhoH PF02562.16 CCC67934.1 - 4.5e-05 23.0 0.4 0.19 11.2 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.27 CCC67934.1 - 5.3e-05 23.8 0.0 0.064 13.8 0.0 3.6 2 1 0 2 2 2 1 ABC transporter AAA_28 PF13521.6 CCC67934.1 - 6.5e-05 23.2 0.0 0.59 10.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 CCC67934.1 - 6.8e-05 22.2 0.0 0.072 12.2 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_17 PF13207.6 CCC67934.1 - 8.9e-05 22.9 0.0 0.56 10.6 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.11 CCC67934.1 - 0.00017 21.4 0.0 0.79 9.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 CCC67934.1 - 0.00024 21.0 0.6 0.96 9.2 0.0 2.8 3 0 0 3 3 3 2 AAA domain ResIII PF04851.15 CCC67934.1 - 0.00028 20.9 0.1 0.14 12.2 0.0 2.7 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit TsaE PF02367.17 CCC67934.1 - 0.00031 20.7 0.0 0.57 10.2 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2075 PF09848.9 CCC67934.1 - 0.00065 19.0 0.0 0.96 8.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CCC67934.1 - 0.0009 19.2 0.1 2.2 8.2 0.0 3.5 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 CCC67934.1 - 0.0019 18.0 0.7 2.3 7.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 CCC67934.1 - 0.0028 18.0 0.4 3.6 7.9 0.0 3.1 2 1 1 3 3 2 1 AAA domain ATPase_2 PF01637.18 CCC67934.1 - 0.0042 17.0 3.2 2.5 7.9 0.1 4.1 3 2 1 4 4 3 1 ATPase domain predominantly from Archaea Sigma54_activ_2 PF14532.6 CCC67934.1 - 0.015 15.4 0.0 1.5 8.9 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain IPT PF01745.16 CCC67934.1 - 0.016 14.6 0.1 2.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase Zeta_toxin PF06414.12 CCC67934.1 - 0.02 14.2 0.1 7.3 5.8 0.0 2.9 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.22 CCC67934.1 - 0.029 13.5 0.0 4.9 6.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain KAP_NTPase PF07693.14 CCC67934.1 - 0.036 13.3 0.3 2.1 7.5 0.0 2.8 2 2 1 3 3 3 0 KAP family P-loop domain Zot PF05707.12 CCC67934.1 - 0.045 13.4 0.0 2.7 7.6 0.0 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 CCC67934.1 - 0.057 13.1 0.0 7.9 6.2 0.0 2.7 2 0 0 2 2 2 0 Cytidylate kinase AAA_6 PF12774.7 CCC67934.1 - 0.098 11.6 0.3 5.2 5.9 0.0 2.5 3 0 0 3 3 2 0 Hydrolytic ATP binding site of dynein motor region UFD1 PF03152.14 CCC67934.1 - 0.1 12.1 0.0 0.37 10.2 0.0 1.9 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 NTPase_1 PF03266.15 CCC67934.1 - 0.12 12.3 3.8 8.3 6.3 0.0 4.4 5 0 0 5 5 5 0 NTPase Cyclin_N PF00134.23 CCC67935.1 - 6e-17 61.6 0.1 1.1e-16 60.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCC67935.1 - 1.9e-06 28.4 0.9 2.4e-06 28.0 0.1 1.6 2 0 0 2 2 2 1 Cyclin IATP PF04568.12 CCC67937.1 - 3.1e-11 43.5 3.3 4.3e-11 43.1 3.3 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP XhlA PF10779.9 CCC67937.1 - 0.0025 18.0 2.2 0.0039 17.4 2.2 1.3 1 0 0 1 1 1 1 Haemolysin XhlA AFG1_ATPase PF03969.16 CCC67937.1 - 0.0064 15.4 0.0 0.0065 15.4 0.0 1.0 1 0 0 1 1 1 1 AFG1-like ATPase YvrJ PF12841.7 CCC67937.1 - 0.29 10.7 0.8 0.44 10.1 0.8 1.3 1 0 0 1 1 1 0 YvrJ protein family DivIC PF04977.15 CCC67937.1 - 0.81 9.5 5.9 0.38 10.5 2.6 1.9 1 1 1 2 2 2 0 Septum formation initiator HMGL-like PF00682.19 CCC67938.1 - 1.4e-85 287.1 0.1 2e-85 286.6 0.1 1.2 1 0 0 1 1 1 1 HMGL-like SidE PF12252.8 CCC67938.1 - 0.024 12.2 0.0 0.033 11.7 0.0 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein Trp_syntA PF00290.20 CCC67938.1 - 0.048 12.5 0.0 4.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Cullin PF00888.22 CCC67939.1 - 1.7e-149 499.3 10.2 2.3e-149 498.9 10.2 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 CCC67939.1 - 1.4e-23 82.7 2.3 8.5e-23 80.2 1.0 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain Penicillinase_R PF03965.16 CCC67939.1 - 0.038 14.4 0.1 0.31 11.4 0.0 2.6 2 1 1 3 3 3 0 Penicillinase repressor Z1 PF10593.9 CCC67939.1 - 0.58 9.6 4.0 0.44 10.0 0.1 2.7 3 0 0 3 3 3 0 Z1 domain MARVEL PF01284.23 CCC67940.1 - 0.0016 18.5 4.2 0.0027 17.7 4.2 1.3 1 0 0 1 1 1 1 Membrane-associating domain CreD PF06123.12 CCC67940.1 - 0.013 14.3 0.1 0.028 13.2 0.1 1.5 1 0 0 1 1 1 0 Inner membrane protein CreD DUF3671 PF12420.8 CCC67940.1 - 0.22 11.6 2.8 0.5 10.4 0.9 2.5 2 0 0 2 2 2 0 Protein of unknown function Vma12 PF11712.8 CCC67940.1 - 0.98 9.5 5.0 0.43 10.7 1.1 2.6 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ribosomal_L41 PF05162.13 CCC67941.1 - 1.2e-10 41.2 26.3 1.3e-10 41.2 26.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 ATP-synt_ab PF00006.25 CCC67942.1 - 4.1e-113 376.3 0.0 8.1e-113 375.3 0.0 1.7 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.16 CCC67942.1 - 2.1e-97 325.6 0.2 4e-97 324.7 0.2 1.5 1 0 0 1 1 1 1 Hom_end-associated Hint ATP-synt_ab_Xtn PF16886.5 CCC67942.1 - 6.6e-45 151.9 0.0 1.3e-44 150.9 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension Hom_end PF05204.14 CCC67942.1 - 3.7e-43 146.2 0.1 6.6e-39 132.5 0.0 2.4 2 0 0 2 2 2 2 Homing endonuclease ATP-synt_ab_N PF02874.23 CCC67942.1 - 2.1e-15 57.0 2.5 4.7e-15 55.9 2.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LAGLIDADG_3 PF14528.6 CCC67942.1 - 2e-06 28.0 0.0 0.00017 21.8 0.1 2.7 2 0 0 2 2 2 1 LAGLIDADG-like domain Hint PF01079.20 CCC67942.1 - 0.00042 19.9 0.0 0.001 18.6 0.0 1.6 1 0 0 1 1 1 1 Hint module Hint_2 PF13403.6 CCC67942.1 - 0.0037 17.6 0.1 0.0088 16.4 0.1 1.6 1 0 0 1 1 1 1 Hint domain WhiA_N PF10298.9 CCC67942.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain Mso1_Sec1_bdg PF14475.6 CCC67942.1 - 0.69 9.6 2.5 30 4.3 0.1 3.0 3 0 0 3 3 3 0 Sec1-binding region of Mso1 Metallophos PF00149.28 CCC67943.1 - 2.1e-33 116.6 0.2 3.1e-33 116.0 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Herpes_capsid PF06112.11 CCC67943.1 - 0.78 9.8 2.9 1.2 9.2 2.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Rho_GDI PF02115.17 CCC67944.1 - 1.2e-61 207.9 3.7 1.4e-61 207.7 3.7 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Arf PF00025.21 CCC67945.1 - 3.4e-78 261.1 0.0 3.9e-78 260.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCC67945.1 - 1.4e-14 54.3 0.1 1.9e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CCC67945.1 - 3.5e-14 52.7 0.0 3.7e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CCC67945.1 - 7.4e-14 51.6 0.0 8.9e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCC67945.1 - 5.4e-12 45.5 1.0 4.1e-08 32.8 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCC67945.1 - 1.4e-09 37.7 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCC67945.1 - 1.9e-05 24.7 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 CCC67945.1 - 0.0081 15.8 0.2 0.015 14.9 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 CCC67945.1 - 0.039 14.5 0.1 0.072 13.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CCC67945.1 - 0.041 14.1 0.6 0.1 12.8 0.6 1.9 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 CCC67945.1 - 0.05 12.9 0.2 0.074 12.3 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.19 CCC67945.1 - 0.053 13.1 0.1 7.5 6.1 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 CCC67945.1 - 0.056 13.0 0.1 0.16 11.5 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCC67945.1 - 0.06 13.2 0.1 8.9 6.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 CCC67945.1 - 0.09 13.3 0.1 0.14 12.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CCC67945.1 - 0.15 12.0 0.4 14 5.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Sugar_tr PF00083.24 CCC67946.1 - 4.4e-128 428.0 27.3 5.6e-128 427.6 27.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC67946.1 - 6e-20 71.5 31.8 4.2e-14 52.3 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Scm3 PF10384.9 CCC67947.1 - 2.2e-19 68.9 1.1 2.2e-19 68.9 1.1 2.4 2 0 0 2 2 2 1 Centromere protein Scm3 RNA_pol_Rpb1_1 PF04997.12 CCC67948.1 - 3.7e-114 381.3 0.0 7.7e-114 380.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 CCC67948.1 - 3.7e-107 357.7 0.1 5.6e-107 357.1 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CCC67948.1 - 5.8e-78 260.8 0.0 1.7e-77 259.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 CCC67948.1 - 1.2e-61 207.9 0.3 2.4e-61 206.9 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 CCC67948.1 - 2.4e-47 160.3 3.6 4.8e-47 159.3 3.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 CCC67948.1 - 1.3e-45 155.1 0.0 3.5e-45 153.7 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CCC67948.1 - 3.7e-35 120.1 0.1 9.6e-35 118.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 CCC67948.1 - 1.2e-10 41.2 277.1 0.034 14.5 14.6 14.1 3 1 21 24 24 24 21 RNA polymerase Rpb1 C-terminal repeat DUF4123 PF13503.6 CCC67948.1 - 0.11 12.9 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) BPL_N PF09825.9 CCC67949.1 - 3.4e-118 395.0 0.0 4.1e-118 394.7 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.19 CCC67949.1 - 2.6e-20 72.7 0.0 5.1e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 CCC67949.1 - 2.9e-10 39.9 0.0 5.2e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Cpn60_TCP1 PF00118.24 CCC67950.1 - 7.2e-147 490.0 11.6 8.1e-147 489.8 11.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ApbA_C PF08546.11 CCC67951.1 - 2.5e-27 95.6 0.0 3.8e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 CCC67951.1 - 1.9e-20 73.1 0.0 2.7e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DAO PF01266.24 CCC67951.1 - 0.15 11.6 0.5 0.22 11.1 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Coatomer_WDAD PF04053.14 CCC67952.1 - 1.8e-129 432.7 5.6 3e-129 432.0 5.6 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.11 CCC67952.1 - 2.1e-83 280.4 0.2 3e-83 279.8 0.2 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 CCC67952.1 - 1e-40 137.0 17.8 1.3e-07 32.1 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC67952.1 - 7.3e-11 42.2 0.5 0.0007 19.8 0.0 6.0 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCC67952.1 - 5.4e-05 22.0 6.8 0.33 9.5 0.1 4.1 2 1 1 4 4 4 3 Nucleoporin Nup120/160 DUF2013 PF09431.10 CCC67953.1 - 1e-42 145.6 12.1 1e-42 145.6 12.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) PCI PF01399.27 CCC67954.1 - 2.1e-21 76.4 2.1 4.7e-21 75.3 0.1 2.5 2 0 0 2 2 2 1 PCI domain RPN5_C PF18098.1 CCC67954.1 - 2.4e-15 56.3 3.7 5.9e-15 55.1 3.7 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain DUF5099 PF17025.5 CCC67954.1 - 0.027 14.9 1.2 0.2 12.1 0.0 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5099) Nop14 PF04147.12 CCC67955.1 - 1.5e-178 595.9 75.5 1.9e-99 334.2 29.7 2.1 1 1 1 2 2 2 2 Nop14-like family APG9 PF04109.16 CCC67956.1 - 2.4e-194 646.8 22.3 3e-194 646.5 22.3 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 RNA_pol_Rpc4 PF05132.14 CCC67957.1 - 1.1e-30 107.0 2.2 1.1e-30 107.0 2.2 3.1 3 0 0 3 3 3 1 RNA polymerase III RPC4 Sas10 PF09368.10 CCC67958.1 - 2.4e-29 101.6 11.6 7.7e-29 100.0 11.6 1.9 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 CCC67958.1 - 5e-05 23.8 0.8 0.00039 21.0 0.8 2.8 1 1 0 1 1 1 1 Sas10/Utp3/C1D family MutS_V PF00488.21 CCC67959.1 - 3.8e-46 157.5 0.1 8.8e-46 156.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCC67959.1 - 2.1e-20 73.8 4.7 4.7e-20 72.6 1.7 2.6 2 1 0 2 2 2 1 MutS domain III PP-binding_2 PF14573.6 CCC67959.1 - 0.0091 16.2 2.4 0.02 15.1 0.2 2.7 3 0 0 3 3 3 1 Acyl-carrier AAA_14 PF13173.6 CCC67959.1 - 0.053 13.6 1.8 2.4 8.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 CCC67959.1 - 0.075 12.8 0.3 0.17 11.7 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NUC PF18510.1 CCC67959.1 - 0.38 11.2 6.0 2.3 8.6 1.1 2.9 1 1 1 2 2 2 0 Nuclease domain Cyclin_N PF00134.23 CCC67960.1 - 6.8e-43 145.4 0.4 1.7e-42 144.1 0.4 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCC67960.1 - 1.2e-32 112.5 2.4 5e-31 107.3 0.1 2.7 2 1 0 2 2 2 2 Cyclin, C-terminal domain WD40 PF00400.32 CCC67961.1 - 2.7e-07 31.2 4.3 0.047 14.6 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC67961.1 - 0.0061 16.8 0.0 7.4 7.0 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3918 PF13056.6 CCC67962.1 - 0.061 12.9 0.3 2.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) Pkinase PF00069.25 CCC67963.1 - 1.3e-67 228.0 0.0 1.8e-67 227.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC67963.1 - 1.1e-38 133.0 0.0 1.6e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCC67963.1 - 1.4e-05 24.2 1.9 4.9e-05 22.4 1.9 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CCC67963.1 - 9.4e-05 21.4 0.0 0.00014 20.8 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CCC67963.1 - 0.0015 17.9 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DEAD PF00270.29 CCC67964.1 - 2.7e-44 151.0 0.1 5.5e-44 150.0 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC67964.1 - 9.1e-30 103.3 2.0 1.3e-28 99.5 0.5 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Dynactin_p62 PF05502.13 CCC67965.1 - 3.9e-05 22.6 12.7 5.3e-05 22.2 12.7 1.2 1 0 0 1 1 1 1 Dynactin p62 family Elf1 PF05129.13 CCC67965.1 - 0.013 15.6 4.6 0.013 15.6 4.6 3.4 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 CCC67965.1 - 0.039 13.9 1.7 0.039 13.9 1.7 5.0 4 1 0 4 4 4 0 zinc-ribbon domain DUF4264 PF14084.6 CCC67965.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) Crust_neurohorm PF01147.17 CCC67965.1 - 0.4 10.5 14.7 0.31 10.9 8.8 2.5 2 1 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family Dimer_Tnp_hAT PF05699.14 CCC67967.1 - 8.1e-09 35.2 0.1 2.8e-08 33.4 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CCC67967.1 - 0.18 11.9 0.5 0.47 10.5 0.5 1.8 1 0 0 1 1 1 0 BED zinc finger DUF3589 PF12141.8 CCC67968.1 - 5.6e-82 275.9 5.0 1.6e-79 267.8 2.6 2.7 2 1 0 2 2 2 1 Beta-mannosyltransferases DNA_ligase_A_M PF01068.21 CCC67969.1 - 1.3e-64 217.6 0.4 2.1e-64 217.0 0.4 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CCC67969.1 - 6.5e-47 160.1 0.8 2.3e-46 158.3 0.0 2.3 3 0 0 3 3 3 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 CCC67969.1 - 6.9e-26 90.7 0.1 6.1e-25 87.7 0.0 2.5 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 CCC67969.1 - 9.5e-06 26.0 0.1 2.6e-05 24.6 0.1 1.7 2 0 0 2 2 2 1 RNA ligase DNA_ligase_OB_2 PF14743.6 CCC67969.1 - 0.02 14.9 0.9 3.2 7.8 0.1 2.7 2 0 0 2 2 2 0 DNA ligase OB-like domain Phasin PF05597.11 CCC67969.1 - 0.029 14.4 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) AsnC_trans_reg PF01037.21 CCC67969.1 - 0.13 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain EF-hand_like PF09279.11 CCC67969.1 - 0.14 12.7 1.2 20 5.8 0.0 3.4 3 0 0 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like zf-Mss51 PF13824.6 CCC67970.1 - 7.6e-19 67.6 0.2 1.9e-18 66.3 0.1 1.7 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.11 CCC67970.1 - 0.0094 15.7 0.0 0.034 13.9 0.0 2.0 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain NOT2_3_5 PF04153.18 CCC67971.1 - 6.7e-30 103.8 0.3 8.6e-30 103.5 0.3 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family AAA_18 PF13238.6 CCC67972.1 - 2.9e-30 105.5 1.0 6.5e-30 104.3 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CCC67972.1 - 7e-07 29.8 0.1 4.3e-06 27.2 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 CCC67972.1 - 3.4e-05 24.2 0.0 7.6e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CCC67972.1 - 3.8e-05 24.0 0.0 0.00069 19.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCC67972.1 - 8.5e-05 22.9 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 CCC67972.1 - 0.00016 22.1 0.0 0.00053 20.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 CCC67972.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_5 PF07728.14 CCC67972.1 - 0.0064 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.17 CCC67972.1 - 0.0065 16.2 0.1 1.2 8.8 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase AAA PF00004.29 CCC67972.1 - 0.013 15.9 0.0 0.026 15.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KTI12 PF08433.10 CCC67972.1 - 0.013 15.0 0.0 0.057 12.9 0.0 1.9 1 1 1 2 2 2 0 Chromatin associated protein KTI12 ADK PF00406.22 CCC67972.1 - 0.015 15.4 0.5 0.71 10.0 0.0 2.4 1 1 1 2 2 2 0 Adenylate kinase Mg_chelatase PF01078.21 CCC67972.1 - 0.015 14.7 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 CCC67972.1 - 0.018 14.3 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T4_Rnl2_C PF18043.1 CCC67972.1 - 0.023 14.8 0.7 0.067 13.3 0.1 2.0 2 0 0 2 2 2 0 T4 RNA ligase 2 C-terminal ABC_tran PF00005.27 CCC67972.1 - 0.033 14.7 0.8 0.11 13.0 0.8 2.0 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.15 CCC67972.1 - 0.037 14.0 0.0 0.072 13.0 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.6 CCC67972.1 - 0.047 13.8 0.0 0.67 10.1 0.0 2.5 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CCC67972.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 CCC67972.1 - 0.062 13.0 0.0 0.097 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 CCC67972.1 - 0.088 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region MeaB PF03308.16 CCC67972.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FtsK_SpoIIIE PF01580.18 CCC67972.1 - 0.11 11.9 0.1 0.25 10.7 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 CCC67972.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain BNIP3 PF06553.12 CCC67972.1 - 4.5 6.9 11.1 49 3.5 0.3 2.0 1 1 1 2 2 2 0 BNIP3 zf-RanBP PF00641.18 CCC67973.1 - 2.4e-21 74.7 12.8 6.3e-11 41.4 3.0 2.7 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.22 CCC67973.1 - 1.8e-08 34.1 0.0 0.0019 18.0 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rubredoxin PF00301.20 CCC67973.1 - 0.0022 18.0 1.7 0.59 10.2 0.2 2.6 2 0 0 2 2 2 2 Rubredoxin DUF4495 PF14906.6 CCC67973.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) DZR PF12773.7 CCC67973.1 - 0.33 11.0 6.9 3.9 7.6 0.9 2.5 2 0 0 2 2 2 0 Double zinc ribbon TackOD1 PF18551.1 CCC67973.1 - 0.47 10.1 3.8 8.2 6.1 0.3 2.4 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 zf-ribbon_3 PF13248.6 CCC67973.1 - 1.1 8.8 3.8 3.4 7.2 0.5 2.7 2 0 0 2 2 2 0 zinc-ribbon domain DUF765 PF05570.11 CCC67973.1 - 1.1 9.5 4.4 0.37 11.0 0.9 2.2 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) Vps36-NZF-N PF16988.5 CCC67973.1 - 1.4 8.3 7.9 8.6 5.8 1.0 3.1 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain ADH_N PF08240.12 CCC67974.1 - 5.2e-26 90.7 3.0 5.2e-26 90.7 3.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCC67974.1 - 6.8e-20 71.4 0.1 1.6e-19 70.2 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CCC67974.1 - 0.0022 17.3 0.7 0.0038 16.6 0.7 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 CCC67974.1 - 0.0062 15.9 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CCC67974.1 - 0.018 14.7 0.1 0.034 13.7 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.6 CCC67974.1 - 0.018 16.1 0.0 0.038 15.0 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Sacchrp_dh_NADP PF03435.18 CCC67974.1 - 0.032 14.5 0.0 0.055 13.7 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain TrkA_N PF02254.18 CCC67974.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain HycI PF01750.18 CCC67974.1 - 0.086 12.7 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Hydrogenase maturation protease Nop PF01798.18 CCC67975.1 - 2e-84 282.6 0.1 2e-84 282.6 0.1 2.0 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CCC67975.1 - 7e-21 74.4 0.2 7e-21 74.4 0.2 2.5 2 0 0 2 2 2 1 NOP5NT (NUC127) domain DUF2052 PF09747.9 CCC67975.1 - 0.22 11.7 24.1 0.31 11.1 24.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) GAGA_bind PF06217.12 CCC67975.1 - 0.39 11.0 21.8 0.62 10.3 21.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 CCC67975.1 - 0.57 10.0 31.4 0.87 9.4 31.4 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RP-C_C PF11800.8 CCC67975.1 - 2.2 8.3 17.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region MCM_bind PF09739.9 CCC67975.1 - 3.6 5.9 22.1 4.9 5.5 22.1 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor GATase_2 PF00310.21 CCC67977.1 - 2.2e-167 557.0 0.0 3.6e-167 556.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 CCC67977.1 - 2.8e-153 510.4 0.1 5.7e-153 509.4 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 CCC67977.1 - 6.5e-110 367.0 0.0 3.5e-108 361.3 0.0 2.3 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 CCC67977.1 - 5e-70 235.0 4.7 1e-69 234.0 4.7 1.5 1 0 0 1 1 1 1 GXGXG motif Pyr_redox_2 PF07992.14 CCC67977.1 - 3.3e-23 82.4 0.1 2.7e-22 79.3 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 CCC67977.1 - 3.9e-23 81.4 0.0 7.8e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster NAD_binding_8 PF13450.6 CCC67977.1 - 4.8e-09 36.3 0.0 1.3e-08 34.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CCC67977.1 - 9.3e-07 29.3 0.1 0.0002 21.8 0.1 3.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCC67977.1 - 1.9e-05 24.1 6.2 0.00091 18.6 0.0 3.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCC67977.1 - 2.3e-05 23.3 0.2 2.3e-05 23.3 0.2 2.4 3 0 0 3 3 3 1 HI0933-like protein Amino_oxidase PF01593.24 CCC67977.1 - 2.4e-05 23.8 0.0 7e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 CCC67977.1 - 0.0002 20.6 0.0 0.00036 19.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCC67977.1 - 0.00057 19.6 0.1 0.002 17.8 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.23 CCC67977.1 - 0.00071 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.7 CCC67977.1 - 0.00085 18.8 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 CCC67977.1 - 0.0057 15.9 0.1 0.022 14.0 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 CCC67977.1 - 0.0065 15.8 0.0 0.013 14.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.6 CCC67977.1 - 0.0072 16.7 0.1 1.8 9.0 0.0 2.8 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 CCC67977.1 - 0.027 14.5 0.2 1.6 8.8 0.0 2.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 CCC67977.1 - 0.032 13.8 0.1 0.18 11.4 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain GATase_6 PF13522.6 CCC67977.1 - 0.032 14.4 0.0 0.12 12.6 0.0 2.0 1 0 0 1 1 1 0 Glutamine amidotransferase domain 2-Hacid_dh_C PF02826.19 CCC67977.1 - 0.04 13.3 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CCC67977.1 - 0.045 14.3 0.2 0.32 11.6 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.6 CCC67977.1 - 0.053 13.5 0.0 0.8 9.7 0.0 2.9 4 0 0 4 4 2 0 FAD-NAD(P)-binding GIDA PF01134.22 CCC67977.1 - 0.097 11.7 2.0 0.2 10.7 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 CCC67977.1 - 0.22 10.5 0.1 0.46 9.5 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein AdoHcyase_NAD PF00670.21 CCC67977.1 - 0.45 10.6 3.9 19 5.3 0.2 2.9 1 1 1 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.18 CCC67977.1 - 0.74 10.1 3.6 0.87 9.9 0.0 2.7 3 0 0 3 3 2 0 TrkA-N domain DUF3602 PF12223.8 CCC67978.1 - 6e-18 65.2 7.1 1.7e-09 38.1 0.1 3.4 2 1 1 3 3 3 3 Protein of unknown function (DUF3602) RtxA PF07634.11 CCC67978.1 - 2.5 8.8 0.0 2.5 8.8 0.0 3.6 4 0 0 4 4 4 0 RtxA repeat FAD-oxidase_C PF02913.19 CCC67979.1 - 4.8e-62 209.8 0.0 6.5e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CCC67979.1 - 2.2e-34 118.2 0.0 4.3e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Vinculin PF01044.19 CCC67979.1 - 0.084 11.1 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Vinculin family RVP_2 PF08284.11 CCC67979.1 - 0.11 12.2 0.0 0.3 10.9 0.0 1.6 2 0 0 2 2 2 0 Retroviral aspartyl protease PALP PF00291.25 CCC67981.1 - 2.5e-78 263.5 0.2 3.3e-78 263.1 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 CCC67981.1 - 3.6e-42 142.0 0.0 2.9e-27 94.3 0.0 2.6 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase TPP_enzyme_N PF02776.18 CCC67982.1 - 6.1e-32 110.6 0.0 1e-31 109.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCC67982.1 - 9.9e-24 83.6 0.0 3.7e-23 81.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCC67982.1 - 1.5e-15 57.3 0.0 2.7e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.16 CCC67982.1 - 0.029 14.1 0.0 0.089 12.6 0.0 1.8 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit tRNA-synt_2b PF00587.25 CCC67983.1 - 5.4e-37 127.5 0.0 8.1e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Sec61_beta PF03911.16 CCC67984.1 - 8.1e-13 48.2 0.1 1e-12 47.8 0.1 1.2 1 0 0 1 1 1 1 Sec61beta family RRM_1 PF00076.22 CCC67985.1 - 6.4e-08 32.3 0.0 1.4e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-binding PF00249.31 CCC67986.1 - 3.1e-13 49.7 4.2 1.4e-11 44.4 0.3 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCC67986.1 - 4e-10 39.8 5.3 1.7e-09 37.7 0.5 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain PP2C PF00481.21 CCC67987.1 - 1.5e-83 280.4 0.0 1.9e-83 280.1 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Chorismate_bind PF00425.18 CCC67988.1 - 5.6e-90 301.4 0.0 1.1e-89 300.5 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.13 CCC67988.1 - 2.6e-31 108.7 0.0 1.4e-29 103.2 0.0 3.1 2 1 1 3 3 3 1 Anthranilate synthase component I, N terminal region POR PF01558.18 CCC67988.1 - 0.031 14.3 0.0 0.094 12.8 0.0 1.7 1 0 0 1 1 1 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Meth_synt_2 PF01717.18 CCC67989.1 - 4.6e-150 499.3 0.0 1.2e-146 488.1 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 CCC67989.1 - 3.7e-122 407.7 0.3 2.8e-115 385.2 0.0 2.6 4 0 0 4 4 4 2 Cobalamin-independent synthase, N-terminal domain IES5 PF17335.2 CCC67990.1 - 1.2e-43 148.0 6.7 1.3e-43 147.9 6.7 1.0 1 0 0 1 1 1 1 Ino80 complex subunit 5 RICTOR_N PF14664.6 CCC67991.1 - 5.2e-99 331.7 14.2 1.2e-98 330.5 14.2 1.7 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 CCC67991.1 - 1.2e-32 111.8 10.0 4.9e-31 106.6 0.2 5.9 6 0 0 6 6 6 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 CCC67991.1 - 8.4e-31 106.6 0.9 6.9e-29 100.4 0.6 3.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 CCC67991.1 - 2.6e-29 101.3 2.3 1.2e-27 95.9 0.3 4.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 TMEM101 PF15111.6 CCC67991.1 - 0.12 12.0 0.1 0.21 11.1 0.1 1.3 1 0 0 1 1 1 0 TMEM101 protein family HR1 PF02185.16 CCC67991.1 - 2.8 8.1 15.5 2.2 8.5 7.1 3.2 1 1 1 2 2 2 0 Hr1 repeat Cnn_1N PF07989.11 CCC67991.1 - 3.8 7.7 11.7 4.3 7.6 0.6 3.8 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 DoxX PF07681.12 CCC67992.1 - 0.023 15.3 1.0 0.037 14.6 1.0 1.3 1 0 0 1 1 1 0 DoxX Proteasome PF00227.26 CCC67993.1 - 2.1e-41 141.5 0.0 2.5e-41 141.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Rad51 PF08423.11 CCC67994.1 - 1.1e-128 427.9 0.0 1.3e-128 427.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 CCC67994.1 - 3.2e-13 49.8 0.0 4.5e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein HHH_5 PF14520.6 CCC67994.1 - 4.7e-10 39.9 0.2 1.2e-09 38.6 0.2 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain AAA_25 PF13481.6 CCC67994.1 - 5.2e-10 39.2 0.0 8.2e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 CCC67994.1 - 3.9e-06 26.4 0.0 8.7e-06 25.2 0.0 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 CCC67994.1 - 0.0042 16.5 0.1 0.028 13.8 0.0 2.0 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 CCC67994.1 - 0.053 13.2 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ssDNA_TraI_N PF18272.1 CCC67994.1 - 0.079 13.0 1.9 1 9.4 1.0 2.4 2 0 0 2 2 2 0 single-stranded DNA binding TraI N-terminal subdomain AAA_22 PF13401.6 CCC67994.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain UCH PF00443.29 CCC67995.1 - 1.3e-66 224.7 5.3 1.3e-66 224.7 5.3 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCC67995.1 - 1.1e-16 61.4 17.1 1.1e-16 61.4 17.1 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Pribosyltran_N PF13793.6 CCC67996.1 - 9.2e-45 151.3 0.1 7.5e-43 145.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 CCC67996.1 - 1.8e-37 129.1 0.7 1.2e-30 107.0 0.3 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 CCC67996.1 - 1.4e-17 63.7 1.5 1e-16 60.9 0.5 2.3 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCC67996.1 - 0.0037 16.7 0.1 0.0059 16.1 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF2007 PF09413.10 CCC67996.1 - 0.077 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative prokaryotic signal transducing protein UQ_con PF00179.26 CCC67997.1 - 6.3e-20 71.2 0.1 9.1e-20 70.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ADH_zinc_N_2 PF13602.6 CCC67998.1 - 6.7e-13 49.9 0.0 1.2e-12 49.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCC67998.1 - 0.095 12.6 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain zf-CSL PF05207.13 CCC67999.1 - 1.6e-19 69.3 0.3 2.6e-19 68.7 0.3 1.4 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.10 CCC67999.1 - 0.0017 18.4 0.3 0.0032 17.5 0.3 1.4 1 0 0 1 1 1 1 Zinc ribbon domain Ribosomal_S8e PF01201.22 CCC68000.1 - 7.1e-56 188.2 2.2 8.5e-56 187.9 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e AAR2 PF05282.11 CCC68001.1 - 3.5e-34 118.8 7.3 4.6e-34 118.4 7.2 1.3 1 1 0 1 1 1 1 AAR2 protein DUF4361 PF14274.6 CCC68001.1 - 0.089 13.1 0.5 0.089 13.1 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4361) HSP70 PF00012.20 CCC68002.1 - 2.1e-259 861.8 8.8 2.3e-259 861.6 8.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCC68002.1 - 6.1e-16 58.1 0.0 9.6e-15 54.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CCC68002.1 - 0.0019 18.0 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CCC68002.1 - 0.018 14.1 0.4 1 8.2 0.1 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.18 CCC68002.1 - 0.08 12.2 0.1 0.08 12.2 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase SWI-SNF_Ssr4 PF08549.10 CCC68002.1 - 0.54 8.8 7.0 0.24 10.0 0.0 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Golgin_A5 PF09787.9 CCC68002.1 - 3.2 7.1 6.1 4 6.8 2.9 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 MAM1 PF10434.9 CCC68004.1 - 1.4e-41 142.9 10.1 7.5e-41 140.5 10.1 1.8 1 1 0 1 1 1 1 Monopolin complex protein MAM1 WD40 PF00400.32 CCC68005.1 - 6.6e-18 64.8 9.0 3.5e-05 24.5 0.3 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC68005.1 - 2e-07 31.2 0.0 0.0023 18.2 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCC68005.1 - 0.0014 17.4 0.2 0.21 10.2 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 CCC68005.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 WD40-like domain Ge1_WD40 PF16529.5 CCC68005.1 - 0.04 12.9 0.1 2.5 7.0 0.0 2.7 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 CCC68006.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.6 1 0 0 1 1 1 1 LisH Aft1_HRR PF11787.8 CCC68006.1 - 3.9 8.7 6.2 3.4 8.9 0.1 3.4 2 1 1 3 3 3 0 Aft1 HRR domain HEAT_EZ PF13513.6 CCC68007.1 - 9.4e-15 54.8 2.5 0.0052 17.3 0.0 8.4 8 0 0 8 8 8 2 HEAT-like repeat IBN_N PF03810.19 CCC68007.1 - 3e-12 46.3 6.4 1e-09 38.2 0.6 4.0 3 0 0 3 3 3 2 Importin-beta N-terminal domain HEAT_2 PF13646.6 CCC68007.1 - 6.5e-10 39.3 2.1 0.33 11.4 0.2 6.7 5 2 3 8 8 8 4 HEAT repeats HEAT PF02985.22 CCC68007.1 - 8.2e-10 38.1 8.6 0.062 13.6 0.0 8.7 10 0 0 10 10 10 2 HEAT repeat Cnd1 PF12717.7 CCC68007.1 - 7e-05 22.9 5.9 0.014 15.4 0.1 4.8 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.12 CCC68007.1 - 0.00019 21.2 0.9 0.035 13.9 0.0 4.4 5 0 0 5 5 5 1 rRNA processing/ribosome biogenesis G-alpha PF00503.20 CCC68007.1 - 0.031 13.4 0.0 0.082 12.0 0.0 1.7 1 0 0 1 1 1 0 G-protein alpha subunit DUF2950 PF11453.8 CCC68007.1 - 0.093 11.9 0.1 0.2 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2950) BP28CT PF08146.12 CCC68007.1 - 0.13 12.1 5.2 8.1 6.3 0.0 4.9 5 1 0 5 5 5 0 BP28CT (NUC211) domain RTP1_C1 PF10363.9 CCC68007.1 - 0.48 10.6 3.7 6.6 7.0 0.0 4.3 4 1 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 Ank_2 PF12796.7 CCC68008.1 - 1.6e-10 41.4 1.8 0.0003 21.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) KilA-N PF04383.13 CCC68008.1 - 3.5e-06 26.8 0.1 3.5e-06 26.8 0.1 3.0 2 1 0 2 2 2 1 KilA-N domain Ank_4 PF13637.6 CCC68008.1 - 4.9e-06 27.0 2.6 0.027 15.1 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 CCC68008.1 - 4e-05 23.8 2.3 0.0047 17.2 0.2 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCC68008.1 - 7.6e-05 22.8 4.7 0.48 11.2 0.2 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 CCC68008.1 - 0.0045 17.4 10.5 0.26 11.8 0.3 4.0 5 0 0 5 5 5 2 Ankyrin repeat LSM PF01423.22 CCC68009.1 - 8.3e-18 63.8 0.4 1.4e-17 63.2 0.4 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCC68009.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain EMP70 PF02990.16 CCC68010.1 - 4e-148 494.3 18.7 4.9e-148 494.0 18.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 PH PF00169.29 CCC68011.1 - 9.5e-21 74.3 0.2 7.6e-20 71.4 0.0 2.6 3 0 0 3 3 3 1 PH domain SH3_1 PF00018.28 CCC68011.1 - 7.3e-12 44.7 0.5 2.2e-11 43.2 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SAM_2 PF07647.17 CCC68011.1 - 1.4e-11 44.4 0.0 2.3e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.6 CCC68011.1 - 1.6e-08 34.2 0.2 3.5e-08 33.2 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.6 CCC68011.1 - 2.4e-07 30.9 0.0 1.8e-05 25.0 0.0 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 CCC68011.1 - 0.00028 21.3 0.0 0.00028 21.3 0.0 3.7 5 1 0 5 5 3 1 Pleckstrin homology domain SAM_1 PF00536.30 CCC68011.1 - 0.00046 20.6 0.0 0.00079 19.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) CNDH2_C PF16858.5 CCC68011.1 - 0.012 15.5 0.7 0.012 15.5 0.7 3.3 4 1 0 4 4 4 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term SH3_2 PF07653.17 CCC68011.1 - 0.021 14.5 0.0 0.05 13.3 0.0 1.7 1 0 0 1 1 1 0 Variant SH3 domain SAM_PNT PF02198.16 CCC68011.1 - 0.037 14.0 0.0 0.076 13.0 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 CCC68011.1 - 0.059 13.2 0.1 0.2 11.5 0.1 1.9 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4515 PF14988.6 CCC68012.1 - 0.03 14.1 0.3 0.044 13.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) zf-C3HC4 PF00097.25 CCC68013.1 - 6e-09 35.6 10.4 9.8e-09 35.0 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 CCC68013.1 - 1.1e-08 34.7 9.4 1.7e-08 34.2 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC68013.1 - 3.8e-07 30.0 8.1 6.9e-07 29.2 8.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CCC68013.1 - 5.9e-07 29.7 10.7 9.2e-07 29.1 10.7 1.3 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 CCC68013.1 - 3.5e-06 26.8 7.2 7.7e-06 25.7 7.2 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CCC68013.1 - 6.5e-06 25.9 10.7 1.7e-05 24.5 10.8 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCC68013.1 - 0.0002 21.3 10.1 0.00033 20.6 10.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CCC68013.1 - 0.0061 16.7 11.1 0.01 16.0 11.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 CCC68013.1 - 0.44 10.4 11.1 2.1 8.2 11.2 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 CCC68013.1 - 1 9.7 7.1 3.2 8.1 7.1 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CCC68013.1 - 1.9 8.3 12.3 0.58 10.0 8.2 2.2 2 0 0 2 2 2 0 RING-like zinc finger Ribosomal_L14 PF00238.19 CCC68014.1 - 9.8e-33 112.8 0.0 1.2e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SH3_1 PF00018.28 CCC68015.1 - 1.4e-13 50.2 0.2 3.2e-13 49.1 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCC68015.1 - 1.2e-10 41.1 0.0 2.1e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCC68015.1 - 2e-09 37.0 0.0 3.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TctB PF07331.11 CCC68015.1 - 0.018 15.3 6.5 0.026 14.8 6.5 1.2 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family SH3_10 PF17902.1 CCC68015.1 - 0.023 14.7 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 SH3 domain DUF1461 PF07314.11 CCC68015.1 - 0.055 13.4 0.2 0.055 13.4 0.2 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1461) Bac_rhodopsin PF01036.18 CCC68015.1 - 1.1 8.8 9.0 0.58 9.7 1.8 2.1 1 1 1 2 2 2 0 Bacteriorhodopsin-like protein Ribosomal_S21 PF01165.20 CCC68016.1 - 1.7e-12 46.8 1.0 3.6e-12 45.8 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 Peptidase_M24 PF00557.24 CCC68017.1 - 7.9e-50 169.4 0.1 1e-49 169.1 0.1 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Mit_KHE1 PF10173.9 CCC68017.1 - 0.0089 16.1 0.2 0.014 15.5 0.2 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Motile_Sperm PF00635.26 CCC68018.1 - 8.3e-26 90.0 0.1 8.3e-26 90.0 0.1 2.2 2 2 1 3 3 3 1 MSP (Major sperm protein) domain TMEM131_like PF12371.8 CCC68018.1 - 0.00015 21.9 2.7 0.00021 21.5 0.1 2.1 2 0 0 2 2 2 1 Transmembrane protein 131-like PapD-like PF14874.6 CCC68018.1 - 0.025 14.7 0.0 0.12 12.5 0.0 1.9 2 0 0 2 2 2 0 Flagellar-associated PapD-like CHD5 PF04420.14 CCC68018.1 - 0.17 11.8 2.3 0.27 11.1 1.9 1.5 1 1 0 1 1 1 0 CHD5-like protein GAGA_bind PF06217.12 CCC68018.1 - 0.21 11.8 4.3 0.27 11.5 4.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Mem_trans PF03547.18 CCC68018.1 - 0.55 8.6 4.2 0.77 8.1 4.2 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF2344 PF10105.9 CCC68018.1 - 1.8 8.4 5.3 2.9 7.7 5.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) Mitofilin PF09731.9 CCC68018.1 - 4.1 6.1 17.7 5.4 5.7 17.7 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Endostatin PF06482.11 CCC68018.1 - 7.5 5.9 7.6 11 5.4 7.6 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Ribosomal_L32e PF01655.18 CCC68019.1 - 4.3e-46 155.8 1.5 5e-46 155.6 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 ArfGap PF01412.18 CCC68020.1 - 2.1e-33 114.9 0.9 2.1e-33 114.9 0.9 2.4 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf Iron_permease PF04120.12 CCC68020.1 - 0.17 11.7 1.0 10 5.9 0.0 2.5 2 0 0 2 2 2 0 Low affinity iron permease TPP_enzyme_N PF02776.18 CCC68021.1 - 5.3e-31 107.5 0.0 8.2e-31 106.9 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCC68021.1 - 1.2e-25 89.9 0.0 6e-25 87.6 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCC68021.1 - 1.2e-13 51.1 0.0 2.9e-13 49.9 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain OCC1 PF15506.6 CCC68021.1 - 0.19 11.9 0.1 3.5 7.8 0.1 2.6 2 0 0 2 2 2 0 OCC1 family Peptidase_M41 PF01434.18 CCC68022.1 - 2.6e-59 200.3 0.1 4.8e-59 199.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 CCC68022.1 - 2.2e-40 138.1 0.0 4.5e-40 137.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC68022.1 - 1.6e-08 34.2 0.0 4.6e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 CCC68022.1 - 1.4e-05 25.5 0.5 0.00012 22.5 0.5 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCC68022.1 - 6.5e-05 23.2 0.2 0.14 12.4 0.1 2.7 1 1 0 2 2 2 2 AAA domain TIP49 PF06068.13 CCC68022.1 - 0.00067 19.0 0.0 0.0012 18.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 CCC68022.1 - 0.0014 18.4 0.0 0.0077 16.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CCC68022.1 - 0.002 18.1 0.1 0.0086 16.1 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 CCC68022.1 - 0.013 15.1 1.0 0.84 9.2 0.4 2.4 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.17 CCC68022.1 - 0.023 14.4 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein ATPase PF06745.13 CCC68022.1 - 0.032 13.6 0.7 0.51 9.6 0.0 2.7 3 0 0 3 3 3 0 KaiC AAA_33 PF13671.6 CCC68022.1 - 0.036 14.2 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 CCC68022.1 - 0.054 12.9 0.2 0.12 11.8 0.2 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CCC68022.1 - 0.057 13.4 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CCC68022.1 - 0.069 13.7 0.3 0.38 11.3 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 CCC68022.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) PhoH PF02562.16 CCC68022.1 - 0.12 11.8 0.6 0.49 9.8 0.2 2.0 2 0 0 2 2 2 0 PhoH-like protein TsaE PF02367.17 CCC68022.1 - 0.13 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE sCache_2 PF17200.4 CCC68022.1 - 0.14 12.0 0.0 2.7 7.8 0.1 2.6 3 0 0 3 3 3 0 Single Cache domain 2 Cyclin_C_2 PF16899.5 CCC68023.1 - 2e-28 98.8 1.0 8.7e-28 96.8 0.1 2.2 2 0 0 2 2 2 1 Cyclin C-terminal domain Cyclin_N PF00134.23 CCC68023.1 - 3e-10 39.9 0.4 6e-10 38.9 0.4 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.19 CCC68023.1 - 0.029 14.4 0.0 0.066 13.3 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Glyco_hydro_65m PF03632.15 CCC68024.1 - 5e-33 114.5 3.7 5.2e-31 107.9 1.6 2.7 2 1 1 3 3 3 2 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.15 CCC68024.1 - 5.6e-26 91.6 0.0 9.1e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.15 CCC68024.1 - 9.7e-06 25.4 0.1 5.9e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain TB2_DP1_HVA22 PF03134.19 CCC68025.1 - 2.8e-24 84.8 4.5 4.2e-24 84.3 4.5 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family WD40_like PF17005.5 CCC68025.1 - 0.096 12.0 0.1 0.14 11.4 0.1 1.1 1 0 0 1 1 1 0 WD40-like domain Adaptin_N PF01602.20 CCC68026.1 - 2.9e-81 273.6 39.6 5.1e-81 272.8 39.6 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 CCC68026.1 - 8.7e-07 29.2 0.2 8.7e-07 29.2 0.2 2.6 3 0 0 3 3 3 1 Adaptin C-terminal domain zf-HC5HC2H_2 PF13832.6 CCC68028.1 - 3e-29 101.4 7.2 3e-29 101.4 7.2 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 CCC68028.1 - 1.3e-27 95.8 5.3 1.3e-27 95.8 5.3 3.2 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 CCC68028.1 - 4.1e-13 48.6 3.3 4.1e-13 48.6 3.3 3.0 3 0 0 3 3 3 1 PHD-finger EPL1 PF10513.9 CCC68028.1 - 7.7e-12 45.9 0.9 7.7e-12 45.9 0.9 2.9 2 1 0 2 2 2 1 Enhancer of polycomb-like PHD PF00628.29 CCC68028.1 - 3.6e-09 36.4 3.8 3.6e-09 36.4 3.8 2.8 2 0 0 2 2 2 2 PHD-finger zf-PHD-like PF15446.6 CCC68028.1 - 0.0071 16.0 1.2 0.0071 16.0 1.2 2.5 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain tRNA-synt_His PF13393.6 CCC68029.1 - 1.1e-36 126.7 0.0 9.2e-36 123.7 0.0 1.9 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 CCC68029.1 - 1.5e-13 50.7 0.0 3e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 CCC68029.1 - 0.032 13.7 0.5 0.081 12.4 0.0 1.8 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 CCC68029.1 - 0.06 12.4 0.1 0.33 10.0 0.1 2.1 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) Actin PF00022.19 CCC68030.1 - 1.1e-54 185.7 1.2 8.8e-40 136.5 0.3 2.0 2 0 0 2 2 2 2 Actin Gln-synt_C PF00120.24 CCC68031.1 - 3.3e-21 75.7 0.0 5.5e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 CCC68031.1 - 1.9e-13 50.0 0.0 3.2e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain V-ATPase_H_N PF03224.14 CCC68032.1 - 2.5e-58 197.9 6.3 2.5e-58 197.9 6.3 1.9 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 CCC68032.1 - 2.3e-41 140.6 1.7 5.2e-40 136.2 0.5 3.0 2 0 0 2 2 2 1 V-ATPase subunit H Arm PF00514.23 CCC68032.1 - 0.06 13.4 0.0 21 5.3 0.0 3.0 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Evr1_Alr PF04777.13 CCC68033.1 - 9.2e-15 54.9 0.0 1.5e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 Erv1 / Alr family TssO PF17561.2 CCC68033.1 - 0.028 14.5 0.0 0.063 13.4 0.0 1.5 1 0 0 1 1 1 0 Type VI secretion system, TssO TIP41 PF04176.13 CCC68034.1 - 8.5e-64 214.2 3.2 1.2e-63 213.7 3.2 1.2 1 0 0 1 1 1 1 TIP41-like family TPR_2 PF07719.17 CCC68035.1 - 1.3e-06 28.0 0.2 9.6e-06 25.3 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCC68035.1 - 1e-05 25.3 0.5 0.0003 20.8 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCC68035.1 - 0.00012 21.7 0.0 0.00039 20.1 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 CCC68035.1 - 0.00015 22.3 0.0 0.0053 17.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF5588 PF17826.1 CCC68035.1 - 0.002 17.1 0.3 0.046 12.6 0.0 2.1 1 1 1 2 2 2 2 Family of unknown function (DUF5588) TPR_6 PF13174.6 CCC68035.1 - 0.0024 18.4 2.5 1.9 9.3 0.0 4.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCC68035.1 - 0.0053 17.4 0.0 0.023 15.4 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCC68035.1 - 0.011 15.7 0.3 0.17 12.0 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4004 PF13171.6 CCC68035.1 - 0.023 14.9 1.6 0.023 14.9 1.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4004) TPR_17 PF13431.6 CCC68035.1 - 0.068 13.6 0.0 2.5 8.7 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat eIF-5_eIF-2B PF01873.17 CCC68036.1 - 5.3e-38 129.5 0.0 1.1e-37 128.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 CCC68036.1 - 1.7e-22 79.4 0.7 4.9e-21 74.7 0.0 2.9 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon PUF PF00806.19 CCC68037.1 - 1.8e-26 90.3 5.2 4.5e-05 22.9 0.0 6.6 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 CCC68037.1 - 0.00014 21.6 0.0 0.0003 20.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PH PF00169.29 CCC68038.1 - 2.4e-06 28.0 0.3 1.3e-05 25.6 0.0 2.5 2 0 0 2 2 2 1 PH domain FYDLN_acid PF09538.10 CCC68038.1 - 8.3 7.1 7.0 1.3 9.7 0.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Ribosomal_L37ae PF01780.19 CCC68039.1 - 4e-39 132.6 10.2 4.4e-39 132.4 10.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 CCC68039.1 - 0.0018 18.4 4.8 0.0026 17.9 4.8 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Lar_restr_allev PF14354.6 CCC68039.1 - 0.0049 17.2 1.6 0.0071 16.7 1.6 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar Rep_fac-A_C PF08646.10 CCC68039.1 - 0.039 13.7 0.9 0.044 13.5 0.9 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain YyzF PF14116.6 CCC68039.1 - 0.58 10.2 0.2 0.58 10.2 0.2 2.0 2 0 0 2 2 2 0 YyzF-like protein Zn_Tnp_IS1595 PF12760.7 CCC68039.1 - 0.63 10.1 5.8 1.2 9.2 5.8 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain CarbpepA_inh PF02977.15 CCC68039.1 - 1.4 8.8 7.1 12 5.7 7.1 2.1 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C4_ClpX PF06689.13 CCC68039.1 - 2.2 8.2 6.7 14 5.7 6.7 2.3 1 1 0 1 1 1 0 ClpX C4-type zinc finger PX PF00787.24 CCC68040.1 - 0.00039 20.4 0.1 0.0007 19.6 0.1 1.4 1 0 0 1 1 1 1 PX domain CHORD PF04968.12 CCC68040.1 - 0.047 14.4 0.1 0.11 13.3 0.1 1.5 1 0 0 1 1 1 0 CHORD tRNA_synt_1c_R2 PF04557.15 CCC68042.1 - 0.78 10.7 9.5 1.1 10.3 1.1 2.4 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 CTP_synth_N PF06418.14 CCC68043.1 - 1.5e-125 417.9 0.4 1.9e-125 417.5 0.4 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 CCC68043.1 - 2.6e-59 200.2 0.0 3.9e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CCC68043.1 - 0.0068 16.2 0.2 0.099 12.4 0.2 2.4 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 CCC68043.1 - 0.087 12.9 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FixP_N PF14715.6 CCC68044.1 - 0.015 15.1 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP ER_lumen_recept PF00810.18 CCC68045.1 - 2e-46 158.4 12.4 2e-46 158.4 12.4 1.5 2 0 0 2 2 2 1 ER lumen protein retaining receptor Proteasome PF00227.26 CCC68046.1 - 1.1e-36 126.1 0.1 8.5e-36 123.2 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit Transp_cyt_pur PF02133.15 CCC68047.1 - 7.6e-155 516.0 42.1 8.9e-155 515.8 42.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3481 PF11980.8 CCC68047.1 - 0.46 10.2 1.8 33 4.3 0.0 3.3 3 0 0 3 3 3 0 C-terminal domain of neuropilin glycoprotein AF-4 PF05110.13 CCC68048.1 - 8.2e-05 20.9 13.5 0.0001 20.6 13.5 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Alpha_Helical PF18489.1 CCC68048.1 - 0.088 13.0 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Alpha helical domain SEEEED PF14797.6 CCC68048.1 - 3.1 8.0 27.2 0.36 11.0 21.9 2.1 1 1 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Peptidase_M16_C PF05193.21 CCC68049.1 - 9.6e-26 90.9 0.1 2.6e-25 89.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCC68049.1 - 1.9e-22 79.9 0.9 3.3e-22 79.1 0.9 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PPP4R2 PF09184.11 CCC68050.1 - 3.4e-62 210.6 10.1 3.4e-62 210.6 10.1 2.1 2 0 0 2 2 2 1 PPP4R2 VanZ PF04892.12 CCC68051.1 - 2.1e-08 34.9 1.2 2.5e-08 34.6 1.2 1.2 1 1 0 1 1 1 1 VanZ like family EF-hand_4 PF12763.7 CCC68052.1 - 1.6e-31 108.3 0.2 9.5e-11 41.6 0.5 4.0 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CCC68052.1 - 4.9e-09 36.5 1.7 0.012 16.0 0.1 4.8 3 1 2 5 5 4 3 EF-hand domain pair UBA PF00627.31 CCC68052.1 - 5e-09 35.9 0.1 2.5e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_6 PF13405.6 CCC68052.1 - 1.2e-08 34.2 0.1 0.89 9.7 0.0 5.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 CCC68052.1 - 2.1e-08 33.1 0.2 0.029 13.9 0.0 4.2 4 0 0 4 4 4 2 EF hand UBA_4 PF14555.6 CCC68052.1 - 0.00038 20.2 0.3 0.0012 18.6 0.3 1.9 1 0 0 1 1 1 1 UBA-like domain DUF3584 PF12128.8 CCC68052.1 - 0.0056 14.3 47.8 0.009 13.6 47.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) FPP PF05911.11 CCC68052.1 - 0.046 11.9 55.6 0.017 13.4 32.8 2.5 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil CUE PF02845.16 CCC68052.1 - 0.051 13.3 0.0 5.4 6.8 0.0 2.8 2 0 0 2 2 2 0 CUE domain Viral_P18 PF04521.13 CCC68052.1 - 0.41 10.4 3.0 1.9 8.3 3.0 2.1 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Atg14 PF10186.9 CCC68052.1 - 1.8 7.6 45.4 0.043 12.9 18.5 2.9 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 EzrA PF06160.12 CCC68052.1 - 4.7 5.3 52.5 1.3 7.2 23.4 2.7 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA TPR_MLP1_2 PF07926.12 CCC68052.1 - 4.7 7.3 62.9 0.69 10.0 19.2 3.8 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 CCC68052.1 - 6.4 5.6 58.2 2.6 6.8 30.0 3.4 1 1 3 4 4 4 0 Spc7 kinetochore protein CMD PF02627.20 CCC68053.1 - 3.2e-05 23.9 0.0 0.00039 20.4 0.0 2.5 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family NPIP PF06409.11 CCC68053.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) Yippee-Mis18 PF03226.14 CCC68054.1 - 1.4e-13 50.9 3.9 2e-13 50.5 3.9 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4451 PF14616.6 CCC68054.1 - 0.008 16.4 1.9 1.5 9.0 1.0 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4451) RIG-I_C-RD PF11648.8 CCC68054.1 - 0.029 14.6 2.3 0.047 13.9 2.3 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I G-alpha PF00503.20 CCC68055.1 - 9.1e-103 344.1 11.8 1.2e-102 343.8 11.8 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CCC68055.1 - 5e-15 55.4 0.2 4.2e-09 36.1 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCC68055.1 - 1e-05 25.0 0.6 0.002 17.5 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 CCC68055.1 - 0.018 15.3 0.5 1.9 8.7 0.2 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CCC68055.1 - 0.025 14.3 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.18 CCC68055.1 - 0.08 12.3 0.0 0.25 10.7 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family Med17 PF10156.9 CCC68056.1 - 4.3e-177 589.5 15.2 5.4e-177 589.1 15.2 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex FAM104 PF15434.6 CCC68056.1 - 0.017 15.7 0.5 0.051 14.1 0.5 1.8 1 0 0 1 1 1 0 Family 104 P5CR_dimer PF14748.6 CCC68057.1 - 6.3e-33 113.1 0.3 1.2e-32 112.3 0.3 1.5 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 CCC68057.1 - 6.4e-10 39.5 0.2 2.3e-09 37.7 0.2 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 CCC68057.1 - 0.0053 16.4 0.0 0.0093 15.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DapB_N PF01113.20 CCC68057.1 - 0.015 15.4 0.1 0.066 13.3 0.1 2.1 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DUF4087 PF13316.6 CCC68057.1 - 0.028 14.9 0.0 0.07 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4087) Ribosomal_S7 PF00177.21 CCC68058.1 - 3.6e-37 127.3 2.4 5.2e-37 126.8 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Carn_acyltransf PF00755.20 CCC68059.1 - 2.1e-114 383.3 0.0 3e-114 382.8 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CmlA_N PF18456.1 CCC68059.1 - 0.11 11.8 0.2 10 5.3 0.0 2.4 2 0 0 2 2 2 0 Diiron non-heme beta-hydroxylase N-terminal domain Zn_clus PF00172.18 CCC68060.1 - 1.4e-08 34.7 11.3 2.8e-08 33.7 11.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro-NT_NN PF07421.11 CCC68060.1 - 0.04 14.2 0.5 0.04 14.2 0.5 2.2 2 0 0 2 2 2 0 Neurotensin/neuromedin N precursor eIF2_C PF09173.11 CCC68061.1 - 5.8e-35 119.4 0.5 1.3e-34 118.3 0.5 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 CCC68061.1 - 3.9e-23 82.0 0.2 3.7e-22 78.8 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 CCC68061.1 - 2.7e-11 43.7 0.4 2.7e-11 43.7 0.4 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCC68061.1 - 0.0039 17.3 0.0 0.0083 16.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCC68061.1 - 0.0046 16.9 0.1 0.085 12.8 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CCC68061.1 - 0.056 13.5 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Pkinase PF00069.25 CCC68062.1 - 8e-75 251.6 0.0 1e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68062.1 - 5e-30 104.6 0.0 2.8e-28 98.9 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCC68062.1 - 1.1e-06 27.9 0.0 1.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain DUF3724 PF12521.8 CCC68062.1 - 0.062 13.2 1.2 0.32 11.0 1.2 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) Seadorna_VP7 PF07387.11 CCC68062.1 - 0.075 12.1 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 CCC68062.1 - 0.19 11.0 0.2 0.6 9.4 0.2 1.8 1 1 0 1 1 1 0 Kinase-like ORC4_C PF14629.6 CCC68063.1 - 1.1e-40 139.4 5.4 1.1e-40 139.4 5.4 2.1 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 CCC68063.1 - 8.5e-05 23.0 0.0 0.0003 21.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 CCC68063.1 - 0.0033 16.5 0.1 0.0054 15.8 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Syntaxin-6_N PF09177.11 CCC68063.1 - 0.42 11.2 6.4 0.46 11.1 0.3 3.5 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Ras PF00071.22 CCC68065.1 - 2.7e-54 183.1 0.0 3.3e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC68065.1 - 2.8e-21 76.0 0.0 5.2e-21 75.1 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC68065.1 - 1.7e-06 27.6 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CCC68065.1 - 0.089 12.2 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CCC68065.1 - 0.097 12.0 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S14 PF00253.21 CCC68066.1 - 6.9e-21 73.8 0.4 1.4e-20 72.8 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e PAPS_reduct PF01507.19 CCC68067.1 - 1.6e-41 142.2 0.0 2.7e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family ANAPC4_WD40 PF12894.7 CCC68068.1 - 3.3e-06 27.3 1.7 0.032 14.5 0.4 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 CCC68068.1 - 0.0002 21.7 0.0 2.6 8.6 0.0 4.1 4 0 0 4 4 4 2 PQQ-like domain WD40 PF00400.32 CCC68068.1 - 0.024 15.5 0.5 7.1 7.7 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Putative_PNPOx PF01243.20 CCC68070.1 - 1.5e-16 60.3 0.0 7.1e-16 58.2 0.0 2.1 2 1 1 3 3 3 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 CCC68070.1 - 0.0035 17.3 0.0 2 8.4 0.0 2.1 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 CCC68070.1 - 0.019 14.5 0.4 0.33 10.5 0.1 2.2 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase like AAA PF00004.29 CCC68071.1 - 6.1e-44 149.6 0.0 1.3e-43 148.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 CCC68071.1 - 1.6e-30 104.9 0.4 4.5e-30 103.4 0.3 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 CCC68071.1 - 6.9e-23 80.5 7.6 2.2e-22 78.9 7.6 1.9 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 CCC68071.1 - 2.1e-06 27.4 0.0 1.8e-05 24.4 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 CCC68071.1 - 7.4e-06 25.8 0.0 1.3e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 CCC68071.1 - 7.8e-06 25.9 0.0 3.3e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCC68071.1 - 8.5e-06 26.2 0.1 0.00011 22.7 0.0 2.4 2 1 1 3 3 3 1 AAA ATPase domain DUF815 PF05673.13 CCC68071.1 - 5.8e-05 22.4 0.0 0.0011 18.2 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CCC68071.1 - 6.9e-05 22.6 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 CCC68071.1 - 7.8e-05 23.0 0.6 0.011 16.1 0.0 2.6 2 1 1 3 3 2 1 AAA domain TIP49 PF06068.13 CCC68071.1 - 8.7e-05 21.9 0.0 0.00016 21.0 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_2 PF07724.14 CCC68071.1 - 0.00013 22.2 0.1 0.0015 18.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CCC68071.1 - 0.00015 22.1 0.3 0.011 16.1 0.0 3.0 3 0 0 3 3 3 1 RNA helicase AAA_14 PF13173.6 CCC68071.1 - 0.00032 20.7 0.2 0.0011 18.9 0.0 2.0 3 0 0 3 3 1 1 AAA domain AAA_18 PF13238.6 CCC68071.1 - 0.00093 19.7 0.0 0.0028 18.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCC68071.1 - 0.0023 18.1 0.0 0.0056 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CCC68071.1 - 0.0037 17.0 0.4 0.011 15.4 0.0 2.0 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.6 CCC68071.1 - 0.01 16.3 0.4 0.039 14.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCC68071.1 - 0.015 14.9 0.1 0.2 11.2 0.1 2.2 1 1 0 2 2 2 0 AAA domain Torsin PF06309.11 CCC68071.1 - 0.024 14.7 0.0 0.048 13.8 0.0 1.4 1 0 0 1 1 1 0 Torsin Mg_chelatase PF01078.21 CCC68071.1 - 0.033 13.6 0.0 0.077 12.4 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CCC68071.1 - 0.041 13.4 0.0 0.1 12.1 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 CCC68071.1 - 0.048 13.0 0.1 4 6.7 0.0 2.4 1 1 1 2 2 2 0 KaiC NACHT PF05729.12 CCC68071.1 - 0.061 13.2 0.0 0.7 9.8 0.0 2.2 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.16 CCC68071.1 - 0.067 12.6 0.1 0.15 11.5 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.26 CCC68071.1 - 0.068 12.9 0.0 0.26 11.0 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 CCC68071.1 - 0.089 11.9 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CPT PF07931.12 CCC68071.1 - 0.18 11.7 0.1 0.43 10.4 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Methyltransf_32 PF13679.6 CCC68071.1 - 0.22 11.5 0.8 11 6.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Use1 PF09753.9 CCC68071.1 - 0.24 11.1 3.8 0.15 11.8 1.9 1.5 2 0 0 2 2 1 0 Membrane fusion protein Use1 NBP1 PF08537.10 CCC68072.1 - 2.3e-19 70.0 10.7 3e-19 69.6 10.7 1.1 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 HalX PF08663.10 CCC68072.1 - 0.04 14.3 0.5 0.079 13.3 0.5 1.5 1 0 0 1 1 1 0 HalX domain FAM76 PF16046.5 CCC68072.1 - 7.1 5.9 14.2 0.71 9.2 9.8 1.5 1 1 1 2 2 2 0 FAM76 protein DNA_pol_E_B PF04042.16 CCC68073.1 - 5.8e-55 185.9 0.7 1e-54 185.1 0.7 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Prenyltrans PF00432.21 CCC68074.1 - 6.7e-68 224.1 1.6 1e-13 50.8 0.1 6.3 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CCC68074.1 - 2.4e-07 30.2 0.0 4.9e-06 25.9 0.0 2.3 2 1 1 3 3 3 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CCC68074.1 - 0.00021 20.5 0.0 3.8 6.5 0.0 4.0 1 1 3 4 4 4 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 CCC68074.1 - 0.0024 16.9 0.0 0.037 13.1 0.0 2.6 1 1 1 2 2 2 1 A-macroglobulin TED domain DUF4576 PF15144.6 CCC68074.1 - 0.098 12.5 0.0 18 5.3 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4576) IIGP PF05049.13 CCC68074.1 - 0.22 10.5 0.0 0.33 10.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) WD40 PF00400.32 CCC68075.1 - 8.1e-39 130.9 23.3 1.7e-08 35.0 0.4 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC68075.1 - 4.4e-17 62.1 2.2 0.00017 21.8 0.0 6.1 2 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCC68075.1 - 1.3e-05 24.7 0.5 0.00048 19.6 0.2 3.4 2 1 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 CCC68075.1 - 1.6e-05 24.9 0.1 0.039 13.8 0.0 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCC68075.1 - 0.011 14.7 0.0 0.51 9.3 0.0 2.7 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein HDA2-3 PF11496.8 CCC68076.1 - 1.3e-93 313.4 0.7 3.2e-93 312.1 0.7 1.7 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF2652 PF10851.8 CCC68076.1 - 0.056 13.6 0.3 0.21 11.7 0.3 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) ThiF PF00899.21 CCC68077.1 - 1.1e-29 103.5 0.0 1.7e-29 102.9 0.0 1.3 1 1 0 1 1 1 1 ThiF family Sec23_trunk PF04811.15 CCC68078.1 - 6e-71 238.9 0.0 8.5e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 CCC68078.1 - 2.8e-29 101.7 0.1 7e-29 100.4 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 CCC68078.1 - 1.3e-26 92.4 0.0 3e-26 91.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 CCC68078.1 - 6.7e-12 45.1 0.0 1.4e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat zf-Sec23_Sec24 PF04810.15 CCC68078.1 - 3e-11 43.2 8.2 7.1e-11 42.0 8.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Vps36-NZF-N PF16988.5 CCC68078.1 - 0.048 13.1 1.2 0.13 11.7 1.2 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PIG-U PF06728.13 CCC68079.1 - 3.1e-103 345.8 42.3 3.7e-103 345.5 42.3 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U LSM PF01423.22 CCC68080.1 - 7.4e-16 57.6 0.1 8.5e-16 57.4 0.1 1.1 1 0 0 1 1 1 1 LSM domain Glycos_transf_2 PF00535.26 CCC68081.1 - 2.3e-31 108.9 0.0 3.1e-31 108.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CCC68081.1 - 2.6e-06 27.5 0.0 3.8e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CCC68081.1 - 0.00028 20.4 0.0 0.00043 19.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Med11 PF10280.9 CCC68082.1 - 2e-15 57.4 0.3 8.3e-15 55.5 0.3 1.7 1 1 0 1 1 1 1 Mediator complex protein SUKH-3 PF14433.6 CCC68082.1 - 0.0032 18.0 0.0 0.0036 17.8 0.0 1.1 1 0 0 1 1 1 1 SUKH-3 immunity protein CPDase PF07823.11 CCC68082.1 - 0.041 13.6 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein hDGE_amylase PF14701.6 CCC68083.1 - 4.3e-175 583.0 1.3 6e-175 582.6 1.3 1.2 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 CCC68083.1 - 2.6e-130 434.8 0.0 4e-130 434.2 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 CCC68083.1 - 2.4e-76 256.7 0.0 6.2e-76 255.4 0.0 1.7 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 CCC68083.1 - 1.2e-22 79.8 0.1 4.5e-22 78.0 0.1 2.0 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 CCC68083.1 - 2e-06 27.6 0.6 1.3e-05 24.9 0.4 2.3 2 1 1 3 3 3 1 Alpha amylase, catalytic domain ATG13 PF10033.9 CCC68084.1 - 3.9e-63 213.4 0.3 6.4e-63 212.7 0.3 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 DUF2281 PF10047.9 CCC68084.1 - 0.033 14.9 0.2 0.077 13.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) zf-C2H2 PF00096.26 CCC68085.1 - 2.4e-26 90.7 77.3 5.8e-05 23.3 3.3 9.6 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC68085.1 - 2e-19 68.6 76.6 0.00025 21.6 3.9 10.2 10 1 0 10 10 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCC68085.1 - 2.6e-10 40.2 79.2 0.00031 21.0 0.6 10.7 11 0 0 11 11 11 5 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCC68085.1 - 0.00034 20.8 55.7 0.0028 17.9 1.6 8.4 10 0 0 10 10 10 4 Zinc-finger double-stranded RNA-binding CpXC PF14353.6 CCC68085.1 - 0.0085 16.1 1.6 0.0085 16.1 1.6 4.2 2 1 0 3 3 3 1 CpXC protein zf-C2HC_2 PF13913.6 CCC68085.1 - 0.014 15.3 1.0 0.014 15.3 1.0 5.9 6 0 0 6 6 5 0 zinc-finger of a C2HC-type zf-met PF12874.7 CCC68085.1 - 0.035 14.5 0.7 0.035 14.5 0.7 8.9 11 0 0 11 11 11 0 Zinc-finger of C2H2 type zf-C2H2_8 PF15909.5 CCC68085.1 - 0.096 13.0 29.7 0.028 14.7 5.3 5.0 2 1 4 6 6 6 0 C2H2-type zinc ribbon zf-RAG1 PF10426.9 CCC68085.1 - 0.28 11.4 9.0 0.98 9.6 0.1 4.1 3 0 0 3 3 3 0 Recombination-activating protein 1 zinc-finger domain DUF4446 PF14584.6 CCC68085.1 - 0.31 11.0 2.0 0.56 10.2 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) zf-LYAR PF08790.11 CCC68085.1 - 0.35 10.8 19.5 5.4 7.0 0.0 6.1 7 0 0 7 7 6 0 LYAR-type C2HC zinc finger zf-C2H2_2 PF12756.7 CCC68085.1 - 0.38 11.1 48.4 0.25 11.7 2.0 6.4 2 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-C2H2_11 PF16622.5 CCC68085.1 - 1 9.2 16.3 2.1 8.2 0.9 4.2 3 0 0 3 3 3 0 zinc-finger C2H2-type ZapB PF06005.12 CCC68085.1 - 2.6 8.6 10.6 1.2 9.6 8.1 1.8 2 0 0 2 2 2 0 Cell division protein ZapB Vps36-NZF-N PF16988.5 CCC68085.1 - 4.5 6.7 7.3 2.2 7.7 0.0 3.8 4 0 0 4 4 4 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zinc_ribbon_4 PF13717.6 CCC68085.1 - 5.5 7.0 13.9 5 7.1 0.3 4.8 4 0 0 4 4 4 0 zinc-ribbon domain RNA_pol_Rpb6 PF01192.22 CCC68086.1 - 3.3e-17 62.1 0.1 5e-17 61.6 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 EF-hand_7 PF13499.6 CCC68087.1 - 1e-12 48.3 0.7 5.3e-11 42.8 0.0 2.7 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 CCC68087.1 - 1.1e-08 34.2 4.9 5.2e-05 22.9 0.1 5.9 5 1 1 6 6 6 1 EF-hand domain EF-hand_5 PF13202.6 CCC68087.1 - 3.9e-06 26.1 0.3 3.9e-06 26.1 0.3 3.7 5 0 0 5 5 5 1 EF hand EF-hand_1 PF00036.32 CCC68087.1 - 5e-06 25.7 9.3 0.00017 20.9 0.2 4.8 6 0 0 6 6 6 1 EF hand EF-hand_8 PF13833.6 CCC68087.1 - 0.0036 17.1 1.2 0.029 14.2 0.1 3.0 3 1 1 4 4 4 1 EF-hand domain pair DUF1456 PF07308.13 CCC68087.1 - 0.0072 16.6 1.6 0.56 10.6 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1456) SPARC_Ca_bdg PF10591.9 CCC68087.1 - 0.009 16.3 0.2 0.018 15.4 0.0 1.6 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region DUF892 PF05974.12 CCC68087.1 - 0.066 13.2 0.9 0.16 12.0 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF892) AbLIM_anchor PF16182.5 CCC68087.1 - 0.069 13.0 3.0 0.5 10.1 0.1 2.1 1 1 1 2 2 2 0 Putative adherens-junction anchoring region of AbLIM EF-hand_14 PF17959.1 CCC68087.1 - 0.077 13.4 0.9 0.85 10.0 0.1 2.4 2 1 1 3 3 3 0 EF-hand domain B5 PF03484.15 CCC68087.1 - 0.1 12.9 1.6 4 7.8 0.1 2.8 3 1 0 3 3 3 0 tRNA synthetase B5 domain Prefoldin_3 PF13758.6 CCC68087.1 - 0.1 12.7 1.4 0.16 12.0 0.2 1.8 2 0 0 2 2 2 0 Prefoldin subunit Dockerin_1 PF00404.18 CCC68087.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Dockerin type I domain TPR_22 PF18833.1 CCC68088.1 - 3.3e-42 142.5 0.1 1.3e-41 140.6 0.1 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCC68088.1 - 2e-32 111.5 0.7 5.6e-07 30.0 0.0 10.4 9 3 3 12 12 11 6 Tetratricopeptide repeat TPR_2 PF07719.17 CCC68088.1 - 6.8e-27 91.4 2.5 0.00033 20.5 0.0 13.5 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_14 PF13428.6 CCC68088.1 - 1.1e-21 75.6 0.1 0.16 12.8 0.0 12.9 10 4 7 17 17 12 5 Tetratricopeptide repeat TPR_8 PF13181.6 CCC68088.1 - 2.4e-20 71.0 19.5 5.5e-06 26.2 0.0 11.9 13 0 0 13 13 13 5 Tetratricopeptide repeat TPR_1 PF00515.28 CCC68088.1 - 1e-18 66.3 15.5 6.3e-05 22.6 0.0 12.7 15 0 0 15 15 14 3 Tetratricopeptide repeat TPR_16 PF13432.6 CCC68088.1 - 1.3e-18 67.3 0.0 0.0019 18.8 0.0 7.7 6 3 3 9 9 9 5 Tetratricopeptide repeat TPR_11 PF13414.6 CCC68088.1 - 5e-18 64.5 2.2 0.00038 20.1 0.0 9.9 9 2 2 11 11 9 2 TPR repeat TPR_17 PF13431.6 CCC68088.1 - 3.7e-17 61.4 6.7 0.0076 16.6 0.0 9.8 10 1 1 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 CCC68088.1 - 7.1e-16 58.3 8.0 0.003 17.8 0.0 10.0 8 3 2 11 11 11 4 Tetratricopeptide repeat TPR_6 PF13174.6 CCC68088.1 - 1.1e-11 44.5 3.3 0.13 13.0 0.0 9.1 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCC68088.1 - 5.4e-10 38.6 0.1 2.1 8.6 0.0 8.8 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCC68088.1 - 5.9e-10 39.2 0.4 0.78 9.9 0.0 6.6 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 CCC68088.1 - 6.3e-09 35.4 0.3 2 8.4 0.0 7.5 7 0 0 7 7 7 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC68088.1 - 2.3e-07 30.9 10.7 0.0099 16.1 0.0 7.3 8 0 0 8 8 7 1 Anaphase-promoting complex, cyclosome, subunit 3 HrpB1_HrpK PF09613.10 CCC68088.1 - 1.9e-06 27.5 0.3 0.0035 17.0 0.0 5.0 5 1 0 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) Alkyl_sulf_dimr PF14863.6 CCC68088.1 - 7.9e-05 23.1 1.5 0.79 10.2 0.2 3.8 3 1 0 3 3 3 2 Alkyl sulfatase dimerisation TPR_20 PF14561.6 CCC68088.1 - 0.00065 20.0 4.0 12 6.3 0.0 5.7 6 1 1 7 7 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCC68088.1 - 0.0053 16.8 0.2 34 4.6 0.0 5.7 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat TPR_MalT PF17874.1 CCC68088.1 - 0.0078 15.6 0.2 1 8.6 0.0 4.1 5 1 0 5 5 5 1 MalT-like TPR region Coatomer_E PF04733.14 CCC68088.1 - 0.05 13.0 0.0 0.05 13.0 0.0 3.4 4 0 0 4 4 4 0 Coatomer epsilon subunit Wzy_C_2 PF11846.8 CCC68088.1 - 0.15 12.0 0.1 41 4.0 0.0 3.4 3 0 0 3 3 3 0 Virulence factor membrane-bound polymerase, C-terminal RNA_pol_Rpc82 PF05645.13 CCC68089.1 - 3.9e-68 230.0 3.1 1.6e-67 228.0 1.7 2.1 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.11 CCC68089.1 - 5.5e-22 77.6 3.9 2.7e-17 62.6 0.3 3.7 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 CCC68089.1 - 1.9e-07 30.9 2.0 0.0081 16.0 0.2 3.0 3 0 0 3 3 3 2 TFIIE alpha subunit Peptidase_M16 PF00675.20 CCC68090.1 - 3.5e-23 82.2 0.0 6.4e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCC68090.1 - 0.0027 17.7 0.3 0.024 14.7 0.0 2.6 2 1 0 2 2 2 1 Peptidase M16 inactive domain Ribosomal_L27_C PF18471.1 CCC68090.1 - 0.057 12.8 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Ribosomal L27 protein C-terminal domain PALP PF00291.25 CCC68091.1 - 8.1e-59 199.4 0.0 9.1e-59 199.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HGD-D PF06050.13 CCC68091.1 - 0.089 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component DAGK_cat PF00781.24 CCC68091.1 - 0.089 12.4 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Sir1 PF11603.8 CCC68092.1 - 3.1e-24 85.8 1.1 1.7e-18 67.2 0.2 2.9 2 0 0 2 2 2 2 Regulatory protein Sir1 Homeodomain PF00046.29 CCC68093.1 - 4.3e-12 45.7 1.4 7.2e-12 45.0 1.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CCC68093.1 - 9.9e-06 25.4 0.3 9.9e-06 25.4 0.3 1.7 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 CCC68093.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_28 PF13518.6 CCC68093.1 - 0.051 13.7 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Sir1 PF11603.8 CCC68094.1 - 5.5e-10 39.8 1.6 0.00083 19.8 0.0 3.2 2 1 1 3 3 3 2 Regulatory protein Sir1 GFO_IDH_MocA PF01408.22 CCC68095.1 - 1.4e-21 77.5 0.1 3.1e-21 76.4 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CCC68095.1 - 6.9e-09 35.7 0.1 2.3e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Melibiase_C PF17801.1 CCC68095.1 - 0.086 12.9 0.1 4.5 7.4 0.0 2.4 2 0 0 2 2 2 0 Alpha galactosidase C-terminal beta sandwich domain TFIID-18kDa PF02269.16 CCC68096.1 - 5.8e-33 112.8 0.0 9.1e-33 112.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TAF PF02969.17 CCC68096.1 - 0.0038 17.4 0.1 0.02 15.1 0.0 2.1 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CCC68096.1 - 0.017 15.5 8.7 0.022 15.1 0.0 3.1 3 1 0 3 3 3 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCC68096.1 - 0.055 13.8 0.2 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-B_dimeris PF09026.10 CCC68096.1 - 0.16 12.4 5.2 0.25 11.7 5.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.6 CCC68096.1 - 1.5 9.2 9.4 3.5 8.1 9.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ERO1 PF04137.15 CCC68097.1 - 2e-119 399.0 0.4 2e-119 399.0 0.4 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Evr1_Alr PF04777.13 CCC68097.1 - 0.43 11.1 4.3 0.24 11.9 0.8 2.4 2 0 0 2 2 2 0 Erv1 / Alr family Utp14 PF04615.13 CCC68098.1 - 7.6e-199 663.0 74.1 7.6e-199 663.0 74.1 2.1 1 1 1 2 2 2 1 Utp14 protein Proteasome PF00227.26 CCC68099.1 - 3.8e-58 196.1 0.0 4.8e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCC68099.1 - 1.4e-09 37.5 0.2 4.7e-09 35.8 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Rtf2 PF04641.12 CCC68100.1 - 5.7e-39 134.1 2.0 6.5e-39 133.9 2.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 CCC68100.1 - 0.00012 21.9 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.14 CCC68100.1 - 0.008 16.0 0.1 0.008 16.0 0.1 2.6 3 0 0 3 3 3 1 Rad50 zinc hook motif SH3_10 PF17902.1 CCC68100.1 - 0.11 12.6 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 SH3 domain Ish1 PF10281.9 CCC68102.1 - 8.1e-51 170.0 39.0 1.3e-12 47.8 0.1 6.7 6 0 0 6 6 6 5 Putative stress-responsive nuclear envelope protein Apolipoprotein PF01442.18 CCC68102.1 - 2.3e-05 24.4 0.2 0.88 9.4 0.0 4.2 1 1 3 4 4 4 3 Apolipoprotein A1/A4/E domain SAP30_Sin3_bdg PF13867.6 CCC68102.1 - 5e-05 23.5 4.5 0.53 10.7 0.2 4.8 5 0 0 5 5 5 2 Sin3 binding region of histone deacetylase complex subunit SAP30 SAP PF02037.27 CCC68102.1 - 8.8e-05 22.2 0.0 1.8 8.4 0.0 4.3 5 0 0 5 5 5 2 SAP domain Phasin PF05597.11 CCC68102.1 - 0.0021 18.0 6.5 0.082 12.9 0.1 4.6 5 0 0 5 5 5 1 Poly(hydroxyalcanoate) granule associated protein (phasin) YtxH PF12732.7 CCC68102.1 - 0.0025 18.3 23.1 11 6.6 2.1 6.8 4 2 1 5 5 5 1 YtxH-like protein Pro-kuma_activ PF09286.11 CCC68102.1 - 0.014 15.7 1.5 1.1 9.6 0.0 3.8 3 1 0 4 4 4 0 Pro-kumamolisin, activation domain BORCS7 PF16088.5 CCC68102.1 - 0.015 15.5 4.6 0.14 12.4 0.3 4.0 4 0 0 4 4 4 0 BLOC-1-related complex sub-unit 7 DUF883 PF05957.13 CCC68102.1 - 0.081 13.5 3.6 1.1e+02 3.4 0.0 5.1 5 1 0 5 5 5 0 Bacterial protein of unknown function (DUF883) Apo-CII PF05355.11 CCC68102.1 - 0.094 12.9 0.2 0.75 10.0 0.0 2.6 2 0 0 2 2 2 0 Apolipoprotein C-II DUF4230 PF14014.6 CCC68102.1 - 0.15 12.3 10.7 21 5.4 0.2 4.5 2 1 1 4 4 4 0 Protein of unknown function (DUF4230) CoA_transf_3 PF02515.17 CCC68102.1 - 0.19 10.8 0.2 4.7 6.2 0.1 2.1 2 0 0 2 2 2 0 CoA-transferase family III SAM_2 PF07647.17 CCC68102.1 - 1.3 9.2 6.3 23 5.2 0.1 4.9 5 0 0 5 5 5 0 SAM domain (Sterile alpha motif) DLP_helical PF18709.1 CCC68102.1 - 2.5 7.2 14.4 0.38 9.9 0.4 3.9 2 1 1 4 4 4 0 Dynamin-like helical domain CorA PF01544.18 CCC68102.1 - 4.8 6.4 8.7 9 5.5 0.2 3.4 4 0 0 4 4 4 0 CorA-like Mg2+ transporter protein FAD_binding_6 PF00970.24 CCC68104.1 - 5.9e-30 103.5 0.0 9.5e-30 102.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CCC68104.1 - 2.9e-27 95.5 0.0 4.3e-27 94.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CCC68104.1 - 3.8e-05 23.9 0.0 0.0013 18.9 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Tubulin_C PF03953.17 CCC68105.1 - 8.5e-49 164.9 0.1 1.3e-48 164.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.25 CCC68105.1 - 2.7e-28 99.5 0.0 4.5e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Sugar_tr PF00083.24 CCC68106.1 - 1.9e-46 158.9 20.2 2.4e-46 158.5 20.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC68106.1 - 3.3e-23 82.2 16.5 7.3e-14 51.5 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1206 PF06724.11 CCC68106.1 - 0.013 15.5 4.4 1.7 8.8 0.5 3.9 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1206) DUF2852 PF11014.8 CCC68106.1 - 0.039 14.1 0.2 9.6 6.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) FAM178 PF14816.6 CCC68106.1 - 0.12 11.3 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 Gtr1_RagA PF04670.12 CCC68107.1 - 7.5e-93 310.2 3.0 8.4e-93 310.0 2.2 1.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region Ras PF00071.22 CCC68107.1 - 6.2e-09 35.6 0.5 1.9e-08 34.1 0.1 1.8 2 0 0 2 2 2 1 Ras family Roc PF08477.13 CCC68107.1 - 1.6e-08 34.8 0.1 3.9e-08 33.5 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC68107.1 - 1.7e-07 30.9 0.1 3.5e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCC68107.1 - 2.5e-07 30.8 0.0 5.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CCC68107.1 - 0.0046 17.5 0.3 0.011 16.3 0.1 1.9 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 CCC68107.1 - 0.029 14.3 0.5 0.97 9.3 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase DUF815 PF05673.13 CCC68107.1 - 0.033 13.3 0.0 0.07 12.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 CCC68107.1 - 0.035 13.8 0.1 0.077 12.8 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 CCC68107.1 - 0.042 13.2 0.4 0.28 10.5 0.1 2.2 1 1 1 2 2 2 0 AIG1 family Guanylate_kin PF00625.21 CCC68107.1 - 0.066 12.9 1.7 0.23 11.1 0.4 2.4 2 1 0 2 2 2 0 Guanylate kinase Pyr_redox_2 PF07992.14 CCC68108.1 - 1.1e-49 169.3 0.0 1.3e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCC68108.1 - 1.1e-12 48.3 0.2 5.1e-10 39.8 0.2 3.2 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCC68108.1 - 4.4e-07 29.5 1.8 0.015 14.6 0.1 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 CCC68108.1 - 0.044 12.9 0.2 14 4.6 0.0 3.0 2 1 2 4 4 4 0 L-lysine 6-monooxygenase (NADPH-requiring) DUF1451 PF07295.11 CCC68108.1 - 0.095 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon containing domain Miga PF10265.9 CCC68108.1 - 0.14 11.1 0.0 0.14 11.1 0.0 1.8 3 0 0 3 3 3 0 Mitoguardin Ribosomal_L30 PF00327.20 CCC68110.1 - 5.1e-12 45.5 0.5 9.5e-12 44.6 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Herpes_U15 PF05613.11 CCC68110.1 - 0.11 13.2 0.0 0.16 12.7 0.0 1.2 1 0 0 1 1 1 0 Human herpesvirus U15 protein Exo_endo_phos PF03372.23 CCC68111.1 - 3e-20 72.8 0.0 4.1e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nab6_mRNP_bdg PF10567.9 CCC68112.1 - 1.4e-124 415.7 17.4 1.4e-124 415.7 17.4 3.1 3 0 0 3 3 3 1 RNA-recognition motif RRM PF10378.9 CCC68112.1 - 1.5e-18 66.2 6.1 1.5e-18 66.2 6.1 3.4 3 1 0 3 3 3 1 Putative RRM domain RRM_1 PF00076.22 CCC68112.1 - 0.0088 15.9 0.1 0.65 9.9 0.0 3.5 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4841 PF16129.5 CCC68112.1 - 6.7 7.0 6.4 0.82 10.0 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4841) MFS_1 PF07690.16 CCC68113.1 - 1.3e-34 119.7 60.1 4.9e-33 114.5 56.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC68113.1 - 9.8e-05 21.4 9.0 9.8e-05 21.4 9.0 3.0 1 1 2 3 3 3 1 Sugar (and other) transporter Anp1 PF03452.14 CCC68114.1 - 1.4e-121 405.0 0.0 2.9e-121 403.9 0.0 1.6 1 1 0 1 1 1 1 Anp1 TAF8_C PF10406.9 CCC68115.1 - 4.8e-19 68.7 0.2 4.8e-19 68.7 0.2 2.7 2 1 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term SRP1_TIP1 PF00660.17 CCC68116.1 - 0.0013 18.7 2.8 0.0013 18.7 2.8 2.5 2 0 0 2 2 2 1 Seripauperin and TIP1 family N_formyltrans_C PF18216.1 CCC68117.1 - 0.056 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain CTK3_C PF12350.8 CCC68118.1 - 2.7e-17 62.7 6.5 7.4e-17 61.3 6.5 1.7 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.8 CCC68118.1 - 1.1e-06 28.7 3.2 0.009 16.0 0.1 2.6 2 1 1 3 3 3 2 CTD kinase subunit gamma CTK3 SPT6_acidic PF14632.6 CCC68118.1 - 0.36 11.4 2.9 0.69 10.5 2.9 1.4 1 0 0 1 1 1 0 Acidic N-terminal SPT6 SRP1_TIP1 PF00660.17 CCC68119.1 - 4.8e-23 81.1 0.1 1.9e-22 79.2 0.1 2.1 1 0 0 1 1 1 1 Seripauperin and TIP1 family Flocculin_t3 PF13928.6 CCC68119.1 - 6.8e-06 26.5 15.8 6.8e-06 26.5 15.8 6.7 3 2 1 4 4 4 1 Flocculin type 3 repeat CBM_21 PF03370.13 CCC68120.1 - 0.034 14.3 0.3 0.08 13.1 0.3 1.6 2 0 0 2 2 2 0 Carbohydrate/starch-binding module (family 21) SeqA_N PF17206.3 CCC68120.1 - 0.67 9.3 2.0 35 3.8 1.7 2.4 2 0 0 2 2 2 0 SeqA protein N-terminal domain ATP_bind_1 PF03029.17 CCC68121.1 - 2.2e-82 276.5 0.1 3.1e-82 276.0 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 CCC68121.1 - 0.0093 16.5 1.8 0.32 11.5 0.1 2.7 2 1 0 2 2 2 1 AAA domain HUN PF08729.10 CCC68121.1 - 0.022 14.7 1.7 0.055 13.5 1.7 1.7 1 0 0 1 1 1 0 HPC2 and ubinuclein domain MeaB PF03308.16 CCC68121.1 - 0.045 12.7 0.2 0.27 10.2 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 CCC68121.1 - 0.055 13.9 3.4 0.3 11.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCC68121.1 - 0.11 12.9 0.0 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.23 CCC68121.1 - 0.12 12.4 0.0 2.1 8.5 0.0 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 CCC68121.1 - 0.14 12.5 0.0 0.27 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 CCC68121.1 - 0.15 12.4 0.0 0.36 11.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CCC68121.1 - 0.22 11.7 0.4 0.53 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain zf-CCHC_6 PF15288.6 CCC68123.1 - 0.026 14.4 0.3 0.026 14.4 0.3 2.9 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.6 CCC68123.1 - 0.095 12.5 14.6 0.98 9.2 1.2 3.4 3 0 0 3 3 3 0 Zinc knuckle PolC_DP2 PF03833.13 CCC68123.1 - 0.89 7.3 3.7 1.2 6.9 3.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-C2H2_jaz PF12171.8 CCC68123.1 - 1.1 9.6 4.7 12 6.3 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding TBCA PF02970.16 CCC68124.1 - 2.3e-25 88.7 9.6 2.7e-25 88.5 9.6 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A MSP1_C PF07462.11 CCC68124.1 - 0.0036 16.1 6.4 0.0041 15.9 6.4 1.0 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus Fzo_mitofusin PF04799.13 CCC68124.1 - 0.018 14.6 1.9 0.022 14.3 1.9 1.2 1 0 0 1 1 1 0 fzo-like conserved region Phage_GP20 PF06810.11 CCC68124.1 - 0.17 11.7 9.4 0.12 12.2 5.7 1.8 1 1 1 2 2 2 0 Phage minor structural protein GP20 FapA PF03961.13 CCC68124.1 - 0.19 10.3 4.7 0.21 10.2 4.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Csm1_N PF18504.1 CCC68124.1 - 0.24 11.8 6.9 0.3 11.5 4.2 2.4 1 1 1 2 2 2 0 Csm1 N-terminal domain Pkinase PF00069.25 CCC68126.1 - 4e-47 160.8 0.2 3.7e-43 147.8 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68126.1 - 2.7e-18 66.2 0.0 1.1e-17 64.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC68126.1 - 0.031 13.6 0.0 0.057 12.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CCC68126.1 - 0.031 14.2 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 CCC68127.1 - 1.6e-22 79.4 9.7 8.1e-06 26.5 0.4 7.8 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC68127.1 - 5.4e-06 26.6 0.1 0.066 13.5 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCC68127.1 - 0.00014 20.6 0.2 0.0083 14.8 0.1 2.6 3 0 0 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 CCC68127.1 - 0.0012 18.2 0.2 0.25 10.6 0.1 2.2 2 0 0 2 2 2 2 WD40-like domain PQQ_3 PF13570.6 CCC68127.1 - 0.0062 17.0 0.0 0.31 11.6 0.0 3.1 3 1 0 3 3 3 1 PQQ-like domain PQQ PF01011.21 CCC68127.1 - 0.055 13.4 0.1 0.34 10.9 0.1 2.3 3 0 0 3 3 3 0 PQQ enzyme repeat bZIP_1 PF00170.21 CCC68127.1 - 0.15 12.2 0.1 0.36 10.9 0.1 1.6 1 0 0 1 1 1 0 bZIP transcription factor DUF1542 PF07564.11 CCC68127.1 - 4.1 7.6 5.2 1.1 9.4 0.0 2.5 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1542) V_ATPase_I PF01496.19 CCC68128.1 - 0 1013.7 9.8 0 1013.4 9.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Mtc PF03820.17 CCC68129.1 - 7.4e-124 412.8 0.1 8.3e-124 412.7 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier SRP1_TIP1 PF00660.17 CCC68130.1 - 8.5e-27 93.1 1.5 1e-26 92.9 0.1 1.9 2 0 0 2 2 2 1 Seripauperin and TIP1 family Phycoerythr_ab PF02972.14 CCC68130.1 - 0.18 11.7 2.6 0.97 9.3 0.4 2.7 2 1 0 2 2 2 0 Phycoerythrin, alpha/beta chain SRP1_TIP1 PF00660.17 CCC68131.1 - 1.7e-30 105.0 0.4 2.4e-30 104.5 0.4 1.2 1 0 0 1 1 1 1 Seripauperin and TIP1 family WD40 PF00400.32 CCC68132.1 - 4.3e-27 93.8 14.8 1.1e-07 32.4 0.2 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.12 CCC68132.1 - 5.7e-25 87.6 0.4 1.2e-24 86.6 0.4 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 CCC68132.1 - 1.6e-09 36.9 7.0 0.00055 18.7 0.3 4.0 1 1 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 CCC68132.1 - 0.00012 21.0 2.1 0.004 15.9 0.2 3.4 3 1 1 4 4 4 1 Nup133 N terminal like ANAPC4_WD40 PF12894.7 CCC68132.1 - 0.0016 18.7 0.3 0.14 12.5 0.0 3.2 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Phyto-Amp PF15438.6 CCC68132.1 - 0.012 15.4 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 Antigenic membrane protein of phytoplasma MFS_1 PF07690.16 CCC68133.1 - 3.7e-25 88.6 30.1 3.7e-25 88.6 30.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC68133.1 - 0.00083 18.3 0.6 0.00083 18.3 0.6 3.5 2 1 0 3 3 3 2 Sugar (and other) transporter IPPT PF01715.17 CCC68134.1 - 1e-66 225.0 0.1 1e-66 225.0 0.1 1.7 2 0 0 2 2 2 1 IPP transferase IPT PF01745.16 CCC68134.1 - 5.2e-05 22.8 0.1 0.00049 19.6 0.0 2.5 3 1 0 3 3 3 1 Isopentenyl transferase AAA_33 PF13671.6 CCC68134.1 - 0.0022 18.2 0.2 0.0051 17.0 0.0 1.9 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 CCC68134.1 - 0.0064 15.8 0.1 0.024 13.9 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_22 PF13401.6 CCC68134.1 - 0.0064 16.8 0.2 0.76 10.0 0.0 3.1 3 1 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CCC68134.1 - 0.0066 16.4 0.2 0.017 15.0 0.2 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 CCC68134.1 - 0.015 15.9 0.1 0.069 13.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCC68134.1 - 0.028 14.8 0.0 0.37 11.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 CCC68134.1 - 0.034 13.9 0.0 0.094 12.4 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein Hpr_kinase_C PF07475.12 CCC68134.1 - 0.068 12.7 0.0 0.69 9.4 0.0 2.3 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_7 PF12775.7 CCC68134.1 - 0.076 12.5 0.1 0.14 11.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ParA PF10609.9 CCC68134.1 - 0.092 12.2 0.2 0.15 11.5 0.2 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA_25 PF13481.6 CCC68134.1 - 0.11 12.0 0.1 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CCC68134.1 - 2.1 8.8 4.9 1.9 9.0 2.3 2.4 2 1 0 2 2 2 0 ABC transporter BRO1 PF03097.18 CCC68135.1 - 9.9e-81 271.5 13.5 9.9e-81 271.5 13.5 1.5 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CCC68135.1 - 6.7e-24 84.7 21.0 1.8e-23 83.3 12.3 3.8 2 2 1 3 3 3 1 ALIX V-shaped domain binding to HIV CAF20 PF17052.5 CCC68136.1 - 2.5e-50 170.8 1.0 2.8e-50 170.6 1.0 1.0 1 0 0 1 1 1 1 Cap associated factor RRP7 PF12923.7 CCC68136.1 - 0.15 12.2 1.3 0.33 11.1 1.3 1.7 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DnaJ PF00226.31 CCC68137.1 - 3.7e-27 94.2 0.9 3.7e-27 94.2 0.9 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_C PF01556.18 CCC68137.1 - 6.1e-24 84.8 0.1 7.9e-24 84.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CCC68137.1 - 4.7e-14 52.5 16.7 7.9e-14 51.8 16.7 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 CCC68137.1 - 4.4e-07 29.8 6.3 0.00037 20.4 0.9 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 CCC68137.1 - 0.019 15.0 7.7 0.57 10.2 2.0 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Cytochrome_CBB3 PF13442.6 CCC68137.1 - 0.073 13.4 0.5 0.073 13.4 0.5 3.5 2 1 2 4 4 4 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C7 PF14522.6 CCC68137.1 - 0.45 10.5 8.9 1.8 8.6 8.4 2.1 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c TackOD1 PF18551.1 CCC68137.1 - 2.6 7.7 6.5 2.1 8.0 0.8 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 zf-CHY PF05495.12 CCC68137.1 - 3.6 8.2 7.0 12 6.5 7.0 1.8 1 1 0 1 1 1 0 CHY zinc finger Lar_restr_allev PF14354.6 CCC68137.1 - 4.2 7.8 9.7 1.2 9.6 4.6 2.6 2 1 1 3 3 3 0 Restriction alleviation protein Lar GMP_synt_C PF00958.22 CCC68138.1 - 5.2e-45 151.4 0.0 1e-44 150.5 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 CCC68138.1 - 2.3e-42 145.0 0.0 3.8e-42 144.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I NAD_synthase PF02540.17 CCC68138.1 - 5.2e-08 32.3 0.0 1.1e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.13 CCC68138.1 - 9.8e-06 25.5 0.2 9.5e-05 22.3 0.1 2.5 2 1 0 2 2 2 1 Peptidase C26 PAPS_reduct PF01507.19 CCC68138.1 - 0.0074 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 CCC68138.1 - 0.016 14.7 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CCC68138.1 - 0.019 13.8 0.1 0.041 12.7 0.1 1.5 2 0 0 2 2 2 0 tRNA methyl transferase Arginosuc_synth PF00764.19 CCC68138.1 - 0.029 13.7 0.1 0.046 13.0 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase ThiI PF02568.14 CCC68138.1 - 0.056 13.0 0.0 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) ThuA PF06283.11 CCC68138.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation ATP_bind_3 PF01171.20 CCC68138.1 - 0.15 11.8 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 PP-loop family HEM4 PF02602.15 CCC68139.1 - 4.5e-45 153.8 0.0 5.4e-45 153.6 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Ribosomal_L31e PF01198.19 CCC68140.1 - 0.021 15.0 0.1 0.055 13.7 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L31e Post_transc_reg PF13797.6 CCC68140.1 - 0.033 14.0 0.2 0.1 12.5 0.2 1.8 1 0 0 1 1 1 0 Post-transcriptional regulator FlxA PF14282.6 CCC68140.1 - 8.5 6.4 11.8 0.22 11.5 0.5 3.2 3 0 0 3 3 3 0 FlxA-like protein FSH1 PF03959.13 CCC68141.1 - 8.1e-68 228.2 0.0 1.1e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CCC68141.1 - 3.8e-05 23.6 0.4 0.00013 21.9 0.1 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.18 CCC68141.1 - 0.0025 17.4 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 CCC68141.1 - 0.021 14.1 0.0 0.044 13.0 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCC68141.1 - 0.1 12.2 0.6 1.9 8.1 0.4 2.6 2 1 0 2 2 2 0 alpha/beta hydrolase fold Spermine_synt_N PF17284.2 CCC68141.1 - 0.1 12.5 0.0 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 Spermidine synthase tetramerisation domain UCH PF00443.29 CCC68142.1 - 1.4e-55 188.6 7.9 1.8e-55 188.2 7.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCC68142.1 - 3e-17 63.2 11.3 3e-17 63.2 11.3 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CCC68142.1 - 9.5e-11 41.9 6.3 9.5e-11 41.9 6.3 3.5 4 1 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UPF0047 PF01894.17 CCC68142.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 C1_2 PF03107.16 CCC68142.1 - 0.21 12.0 0.3 0.13 12.6 1.1 4.4 5 0 0 5 5 5 0 C1 domain DZR PF12773.7 CCC68142.1 - 2.8 8.0 17.5 2 8.5 2.2 4.4 4 1 0 4 4 4 0 Double zinc ribbon SR-25 PF10500.9 CCC68142.1 - 3 7.4 8.7 4.6 6.8 8.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Phosducin PF02114.16 CCC68143.1 - 5.4e-09 35.4 1.8 0.0012 17.9 0.0 2.1 2 0 0 2 2 2 2 Phosducin DUF2340 PF10209.9 CCC68143.1 - 0.083 13.3 0.4 0.94 10.0 0.4 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2340) RUN PF02759.19 CCC68143.1 - 0.14 12.1 0.1 0.22 11.5 0.1 1.2 1 0 0 1 1 1 0 RUN domain His_Phos_1 PF00300.22 CCC68144.1 - 7.3e-41 140.0 0.0 9.1e-41 139.7 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ish1 PF10281.9 CCC68144.1 - 0.15 12.4 0.2 4.4 7.7 0.0 2.6 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Rhodanese PF00581.20 CCC68145.1 - 3.1e-17 63.0 0.0 3.7e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.20 CCC68146.1 - 8.9e-11 42.3 0.0 1.1e-10 42.0 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain RRP36 PF06102.12 CCC68147.1 - 2.9e-40 137.9 29.8 2.9e-40 137.9 29.8 2.3 2 1 0 2 2 2 1 rRNA biogenesis protein RRP36 Thioredoxin PF00085.20 CCC68148.1 - 8.4e-25 86.8 0.1 3.4e-24 84.8 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 CCC68148.1 - 2e-07 31.1 0.2 0.0032 17.4 0.0 2.8 1 1 2 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 CCC68148.1 - 3.2e-05 24.3 0.1 0.00018 21.9 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 CCC68148.1 - 0.0012 18.2 0.1 0.0036 16.7 0.0 1.7 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 CCC68148.1 - 0.0017 18.7 0.3 0.069 13.5 0.0 3.1 3 1 1 4 4 4 1 Thioredoxin-like Thioredoxin_7 PF13899.6 CCC68148.1 - 0.0053 16.9 0.0 0.013 15.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.6 CCC68148.1 - 0.0059 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 F plasmid transfer operon protein Glutaredoxin PF00462.24 CCC68148.1 - 0.024 14.9 0.1 0.076 13.2 0.1 1.9 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_3 PF13192.6 CCC68148.1 - 0.083 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain AMMECR1 PF01871.17 CCC68149.1 - 2.2e-35 121.7 0.0 2.6e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 DUF4065 PF13274.6 CCC68150.1 - 1.7 9.6 7.8 1.4 9.8 3.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) TBX PF12598.8 CCC68150.1 - 2 9.3 7.2 3.6 8.5 6.8 1.7 1 1 0 1 1 1 0 T-box transcription factor P5-ATPase PF12409.8 CCC68151.1 - 8.8e-37 126.0 0.0 3.2e-36 124.2 0.0 2.1 1 0 0 1 1 1 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.20 CCC68151.1 - 1.3e-30 106.3 0.2 3e-30 105.1 0.0 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 CCC68151.1 - 1e-15 58.6 0.0 4.2e-07 30.5 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCC68151.1 - 9.1e-07 28.9 0.0 1.9e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCC68151.1 - 0.003 17.4 0.1 4.2 7.0 0.0 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Mpv17_PMP22 PF04117.12 CCC68152.1 - 2.4e-19 69.3 0.8 2.4e-19 69.3 0.8 2.7 2 0 0 2 2 2 1 Mpv17 / PMP22 family S10_plectin PF03501.15 CCC68153.1 - 2.9e-42 142.7 0.8 3.3e-42 142.5 0.8 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF4364 PF14277.6 CCC68153.1 - 0.014 15.2 0.4 0.024 14.4 0.4 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4364) MsyB PF13984.6 CCC68153.1 - 0.031 14.6 0.1 0.04 14.2 0.1 1.2 1 0 0 1 1 1 0 MsyB protein HTH_45 PF14947.6 CCC68153.1 - 0.048 13.7 0.3 0.089 12.8 0.3 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix PadR PF03551.14 CCC68153.1 - 0.049 13.6 0.6 0.049 13.6 0.6 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family RRS1 PF04939.12 CCC68154.1 - 1.5e-60 203.7 2.5 1.8e-60 203.5 2.5 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) SWIB PF02201.18 CCC68155.1 - 4.7e-19 68.0 0.0 1e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Iron_traffic PF04362.14 CCC68155.1 - 0.14 11.9 0.1 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Membr_traf_MHD PF10540.9 CCC68156.1 - 1.6e-32 112.7 0.3 1.5e-31 109.6 0.0 2.9 2 0 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.30 CCC68156.1 - 1.5e-08 34.8 0.0 4.2e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 C2 domain DUF810 PF05664.11 CCC68156.1 - 0.00061 18.5 1.6 0.0011 17.6 0.1 2.0 2 0 0 2 2 2 1 Plant family of unknown function (DUF810) TAN PF11640.8 CCC68156.1 - 0.073 13.2 1.0 0.25 11.5 0.2 2.4 2 0 0 2 2 2 0 Telomere-length maintenance and DNA damage repair EST1 PF10374.9 CCC68156.1 - 0.43 11.2 14.7 1.9 9.1 0.4 4.2 2 1 1 3 3 3 0 Telomerase activating protein Est1 Oxidored_FMN PF00724.20 CCC68157.1 - 9.6e-130 432.8 0.0 1.1e-129 432.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF5442 PF17514.2 CCC68157.1 - 0.03 14.5 0.1 0.43 10.8 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5442) Cauli_VI PF01693.16 CCC68158.1 - 1.2e-30 105.5 8.8 1e-19 70.6 4.4 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 CCC68158.1 - 3.7e-29 101.8 0.1 9.7e-29 100.4 0.0 1.8 2 0 0 2 2 2 1 RNase H Peptidase_Prp PF04327.12 CCC68158.1 - 0.3 11.4 1.7 22 5.4 0.3 3.0 2 1 0 2 2 2 0 Cysteine protease Prp CybS PF05328.12 CCC68159.1 - 4.5e-42 142.9 0.0 5.9e-42 142.5 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Acyltransf_C PF16076.5 CCC68160.1 - 1.1e-07 31.8 1.0 1.3e-06 28.4 0.1 3.0 3 0 0 3 3 3 1 Acyltransferase C-terminus Acyltransferase PF01553.21 CCC68160.1 - 0.0014 18.3 0.1 0.044 13.4 0.1 2.6 1 1 0 2 2 2 1 Acyltransferase Ssl1 PF04056.14 CCC68160.1 - 0.012 15.4 0.7 0.027 14.3 0.7 1.5 1 0 0 1 1 1 0 Ssl1-like YbaJ PF10757.9 CCC68160.1 - 0.061 13.9 5.6 1.4 9.5 0.0 3.4 2 2 1 3 3 3 0 Biofilm formation regulator YbaJ DUF3606 PF12244.8 CCC68160.1 - 0.19 11.7 0.1 13 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) ChAPs PF09295.10 CCC68161.1 - 9.6e-168 558.2 2.5 1.2e-167 557.9 2.5 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 CCC68161.1 - 0.00028 21.1 0.9 0.42 10.9 0.1 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 CCC68161.1 - 0.0096 16.4 0.3 1.6 9.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCC68161.1 - 0.01 15.9 4.5 0.057 13.6 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCC68161.1 - 0.078 13.7 1.3 56 4.7 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 CCC68161.1 - 0.15 11.9 0.3 1.4 8.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RGS PF00615.19 CCC68162.1 - 0.00022 21.5 1.0 0.0021 18.3 0.2 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain Leader_CPA1 PF08252.11 CCC68163.1 - 1.1e-16 59.9 4.0 1.2e-16 59.8 4.0 1.0 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide GATase PF00117.28 CCC68164.1 - 8.5e-48 162.6 0.0 1.2e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.22 CCC68164.1 - 3.2e-45 153.1 0.0 4.9e-45 152.5 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.13 CCC68164.1 - 0.00024 21.0 0.4 0.0021 17.8 0.1 2.5 1 1 1 2 2 2 1 Peptidase C26 SNF2_N PF00176.23 CCC68165.1 - 1.3e-75 254.3 0.9 2.5e-75 253.4 0.9 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 CCC68165.1 - 2.4e-39 133.9 4.1 2.4e-39 133.9 4.1 4.3 4 0 0 4 4 4 1 SLIDE HAND PF09110.11 CCC68165.1 - 4.2e-33 114.4 18.1 4.2e-33 114.4 18.1 4.0 4 1 0 4 4 4 1 HAND Helicase_C PF00271.31 CCC68165.1 - 1e-20 74.1 0.1 2.5e-18 66.4 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC68165.1 - 3.3e-12 46.8 0.0 3.3e-12 46.8 0.0 4.2 4 2 1 5 5 5 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCC68165.1 - 1.9e-05 24.5 0.0 5.4e-05 23.0 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase OTCace_N PF02729.21 CCC68165.1 - 0.21 11.6 2.4 0.49 10.4 0.1 2.5 2 0 0 2 2 2 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Laminin_II PF06009.12 CCC68166.1 - 0.00078 19.5 3.3 0.00095 19.2 3.3 1.0 1 0 0 1 1 1 1 Laminin Domain II T3SSipB PF16535.5 CCC68166.1 - 0.0029 18.1 1.6 0.0032 18.0 1.6 1.0 1 0 0 1 1 1 1 Type III cell invasion protein SipB Dor1 PF04124.12 CCC68166.1 - 0.036 12.8 0.7 0.036 12.8 0.7 1.0 1 0 0 1 1 1 0 Dor1-like family Fib_alpha PF08702.10 CCC68166.1 - 0.052 13.7 2.0 0.06 13.5 2.0 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family PCRF PF03462.18 CCC68166.1 - 0.054 13.4 2.2 0.054 13.4 2.2 1.0 1 0 0 1 1 1 0 PCRF domain Baculo_PEP_C PF04513.12 CCC68166.1 - 0.093 12.8 1.1 0.12 12.4 1.1 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 CCC68166.1 - 0.37 11.1 3.2 0.6 10.4 3.2 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2034 PF10356.9 CCC68167.1 - 6.4e-54 182.2 0.1 7.9e-54 181.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.12 CCC68167.1 - 0.0083 16.1 0.0 0.35 10.9 0.0 2.2 2 0 0 2 2 2 1 Restriction endonuclease MFS_1 PF07690.16 CCC68168.1 - 1.7e-28 99.6 47.0 3.3e-23 82.2 28.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC68168.1 - 6.4e-10 38.5 29.0 2.9e-09 36.3 29.0 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4231 PF14015.6 CCC68168.1 - 0.015 15.8 0.7 0.19 12.2 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) TPT PF03151.16 CCC68169.1 - 6.4e-30 104.5 26.1 6.9e-28 97.8 26.1 3.1 1 1 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 CCC68169.1 - 0.00034 20.8 31.6 0.046 13.9 0.8 3.8 3 1 0 3 3 3 3 EamA-like transporter family SART-1 PF03343.13 CCC68170.1 - 4.6e-45 154.3 55.7 1.5e-37 129.5 50.0 3.5 1 1 1 2 2 2 2 SART-1 family Nop PF01798.18 CCC68171.1 - 2.3e-81 272.6 0.4 2.3e-81 272.6 0.4 2.2 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 CCC68171.1 - 2.5e-19 69.4 2.0 2.5e-19 69.4 2.0 2.5 2 1 0 2 2 2 1 NOP5NT (NUC127) domain Aldolase PF01081.19 CCC68171.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 KDPG and KHG aldolase DUF4604 PF15377.6 CCC68171.1 - 0.43 11.0 44.5 0.77 10.2 44.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.12 CCC68171.1 - 2.1 8.1 32.8 4.9 6.9 32.8 1.7 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GAGA_bind PF06217.12 CCC68171.1 - 6.2 7.0 22.7 13 5.9 22.7 1.6 1 0 0 1 1 1 0 GAGA binding protein-like family Nop14 PF04147.12 CCC68171.1 - 9.8 4.2 45.1 0.77 7.9 40.4 1.5 2 0 0 2 2 2 0 Nop14-like family Ribosomal_L18A PF01775.17 CCC68173.1 - 3e-43 146.8 3.7 3e-43 146.8 3.7 1.4 2 0 0 2 2 2 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Cation_efflux PF01545.21 CCC68176.1 - 4.2e-55 186.6 2.8 6.1e-55 186.1 2.8 1.2 1 0 0 1 1 1 1 Cation efflux family Bac_rhodopsin PF01036.18 CCC68177.1 - 2.7e-57 193.9 20.0 3.1e-57 193.7 20.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.6 CCC68177.1 - 0.2 11.3 10.4 0.93 9.1 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RRM_1 PF00076.22 CCC68179.1 - 9.6e-23 79.8 1.8 9.4e-13 47.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCC68179.1 - 3.5e-06 26.6 1.5 0.00056 19.5 0.2 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC68179.1 - 0.0049 16.9 1.8 0.7 10.1 0.2 2.7 2 2 0 2 2 2 2 RNA recognition motif Glyco_transf_8 PF01501.20 CCC68180.1 - 6e-05 22.7 8.7 0.012 15.2 2.2 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 8 zf-C3HC4_4 PF15227.6 CCC68183.1 - 6.6e-10 39.0 10.0 6.6e-10 39.0 10.0 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CCC68183.1 - 2e-08 34.0 9.4 2e-08 34.0 9.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC68183.1 - 7.3e-08 32.3 5.0 7.3e-08 32.3 5.0 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CCC68183.1 - 3e-07 30.2 5.5 3e-07 30.2 5.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCC68183.1 - 5.4e-07 29.8 7.6 5.4e-07 29.8 7.6 2.3 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 CCC68183.1 - 1.1e-05 25.2 4.9 1.1e-05 25.2 4.9 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CCC68183.1 - 1.7e-05 24.5 8.3 1.7e-05 24.5 8.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCC68183.1 - 5.9e-05 23.0 7.1 5.9e-05 23.0 7.1 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CCC68183.1 - 0.007 16.4 1.7 0.007 16.4 1.7 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CCC68183.1 - 0.012 15.9 6.7 0.012 15.9 6.7 2.5 2 1 0 2 2 2 0 RING-H2 zinc finger domain Zn-ribbon_8 PF09723.10 CCC68183.1 - 0.046 13.8 8.0 0.42 10.8 0.9 2.9 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_9 PF14369.6 CCC68183.1 - 0.055 13.7 1.4 0.055 13.7 1.4 3.1 3 1 0 3 3 2 0 zinc-ribbon DZR PF12773.7 CCC68183.1 - 0.056 13.5 10.9 0.57 10.2 0.4 2.7 2 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.12 CCC68183.1 - 0.072 13.1 10.3 0.36 10.8 0.2 2.7 2 1 1 3 3 3 0 zinc-ribbons Mgr1 PF08602.10 CCC68183.1 - 0.075 11.9 0.0 0.075 11.9 0.0 1.9 2 0 0 2 2 2 0 Mgr1-like, i-AAA protease complex subunit zf-RING_4 PF14570.6 CCC68183.1 - 0.083 12.7 13.7 1.1 9.1 6.9 2.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain HypA PF01155.19 CCC68183.1 - 0.41 10.7 9.8 1.2 9.2 1.0 2.6 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn_Tnp_IS91 PF14319.6 CCC68183.1 - 6.8 6.8 12.4 8.4 6.5 3.6 3.0 2 1 1 3 3 3 0 Transposase zinc-binding domain zf-RING_10 PF16685.5 CCC68183.1 - 8.4 6.6 11.3 0.11 12.7 3.0 2.1 2 1 0 2 2 2 0 zinc RING finger of MSL2 Glyco_transf_20 PF00982.21 CCC68184.1 - 1.5e-169 564.7 2.0 1.5e-169 564.7 2.0 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CCC68184.1 - 5.2e-42 143.6 0.1 1.8e-41 141.8 0.1 1.9 2 0 0 2 2 2 1 Trehalose-phosphatase TFIIA PF03153.13 CCC68184.1 - 0.48 10.4 13.7 0.68 9.9 12.5 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CUE PF02845.16 CCC68185.1 - 9.4e-08 31.6 0.0 1.4e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 CUE domain Na_trans_assoc PF06512.13 CCC68185.1 - 0.0087 16.4 8.7 0.011 16.1 8.7 1.1 1 0 0 1 1 1 1 Sodium ion transport-associated SICA_C PF12879.7 CCC68185.1 - 0.054 13.5 1.5 0.064 13.3 1.5 1.2 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain CCDC106 PF15794.5 CCC68185.1 - 0.22 11.2 10.4 0.087 12.5 4.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 DNA_pol_phi PF04931.13 CCC68185.1 - 0.76 7.8 14.7 0.91 7.5 14.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi Tub_N PF16322.5 CCC68185.1 - 1.7 9.0 14.2 2.1 8.7 14.2 1.1 1 0 0 1 1 1 0 Tubby N-terminal PAF PF15715.5 CCC68185.1 - 2.6 8.6 11.1 11 6.6 0.0 2.1 2 0 0 2 2 2 0 PCNA-associated factor histone like domain Kei1 PF08552.11 CCC68185.1 - 3.9 7.3 7.2 37 4.1 7.2 2.0 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TPX2_importin PF12214.8 CCC68185.1 - 4.7 7.4 10.0 0.24 11.6 1.0 2.2 1 1 1 2 2 2 0 Cell cycle regulated microtubule associated protein WD40 PF00400.32 CCC68186.1 - 1.9e-22 79.1 11.4 6.2e-05 23.7 0.2 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC68186.1 - 4.8e-15 55.6 0.1 1.4e-05 25.3 0.0 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCC68186.1 - 3.1e-05 24.0 0.4 0.11 12.4 0.0 3.4 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCC68186.1 - 0.0029 16.6 0.1 0.28 10.1 0.0 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCC68186.1 - 0.038 13.3 2.6 0.071 12.4 0.0 2.4 3 0 0 3 3 3 0 WD40-like domain Bac_rhodopsin PF01036.18 CCC68187.1 - 2.1e-59 200.8 15.5 2.5e-59 200.6 15.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.6 CCC68187.1 - 0.82 9.3 8.6 3.7 7.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Nup188 PF10487.9 CCC68188.1 - 2.1e-251 836.8 54.3 2.1e-251 836.8 54.3 1.7 2 0 0 2 2 2 1 Nucleoporin subcomplex protein binding to Pom34 Nup188_C PF18378.1 CCC68188.1 - 1.1e-21 77.1 8.0 1.1e-21 77.1 8.0 2.0 2 0 0 2 2 2 1 Nuclear pore protein NUP188 C-terminal domain PXA PF02194.15 CCC68189.1 - 3e-33 115.3 3.8 1e-32 113.6 3.8 2.0 1 0 0 1 1 1 1 PXA domain Nexin_C PF08628.12 CCC68189.1 - 6.5e-23 81.4 2.4 1.2e-22 80.6 0.2 2.4 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.24 CCC68189.1 - 1.9e-13 50.3 3.3 1.9e-13 50.3 3.3 3.1 3 0 0 3 3 3 1 PX domain RGS PF00615.19 CCC68189.1 - 0.0049 17.1 3.0 0.011 16.0 0.3 2.9 2 0 0 2 2 2 1 Regulator of G protein signaling domain SRP19 PF01922.17 CCC68190.1 - 2.2e-29 102.2 0.0 4.7e-29 101.2 0.0 1.6 1 0 0 1 1 1 1 SRP19 protein Pribosyltran PF00156.27 CCC68191.1 - 9.4e-17 61.0 0.2 1.3e-16 60.5 0.2 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain zf-C3HC PF07967.13 CCC68192.1 - 1e-09 38.5 2.0 1e-09 38.5 2.0 2.7 2 2 0 2 2 2 1 C3HC zinc finger-like Rsm1 PF08600.10 CCC68192.1 - 0.00023 21.2 4.1 0.0051 16.9 0.2 3.4 3 0 0 3 3 3 1 Rsm1-like Sgf11 PF08209.11 CCC68192.1 - 0.081 12.5 2.1 3.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Oxidored_FMN PF00724.20 CCC68193.1 - 2.3e-128 428.2 0.0 2.7e-128 428.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF5442 PF17514.2 CCC68193.1 - 0.041 14.1 0.0 0.6 10.3 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5442) DUF1892 PF08987.10 CCC68194.1 - 2.9e-54 181.9 6.9 3.3e-54 181.7 6.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1892) Zds_C PF08632.10 CCC68195.1 - 4.3e-28 96.8 1.5 8.1e-28 95.9 1.5 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ubie_methyltran PF01209.18 CCC68196.1 - 1.7e-96 322.0 0.3 2.1e-96 321.8 0.3 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 CCC68196.1 - 1.2e-10 42.0 0.0 2.1e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC68196.1 - 8.7e-09 35.9 0.0 1.6e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC68196.1 - 7.2e-08 32.4 0.0 9.9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCC68196.1 - 5.4e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC68196.1 - 5.7e-06 27.0 0.0 9.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 CCC68196.1 - 0.0026 17.6 0.0 0.19 11.5 0.0 2.4 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 CCC68196.1 - 0.031 14.3 0.0 0.043 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain ADH_zinc_N PF00107.26 CCC68196.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Bul1_N PF04425.12 CCC68197.1 - 9.8e-176 584.9 8.0 9.8e-176 584.9 8.0 3.2 3 1 1 4 4 4 1 Bul1 N terminus Bul1_C PF04426.12 CCC68197.1 - 7.3e-102 340.4 18.6 7.3e-102 340.4 18.6 4.3 4 1 0 4 4 4 1 Bul1 C terminus Hexapep PF00132.24 CCC68198.1 - 4.4e-06 26.2 1.5 0.02 14.6 1.8 3.6 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CCC68198.1 - 0.00041 20.7 0.0 0.00067 20.0 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 CCC68198.1 - 0.0012 17.9 0.6 0.0036 16.3 0.6 1.7 1 1 0 1 1 1 1 L-fucokinase DUF3519 PF12033.8 CCC68198.1 - 7 7.1 11.1 0.14 12.6 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) AAA PF00004.29 CCC68199.1 - 2.4e-42 144.5 0.0 4.5e-42 143.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC68199.1 - 3.7e-08 33.1 0.1 7.7e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 CCC68199.1 - 1.2e-07 31.6 0.3 1.2e-07 31.6 0.3 1.7 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 CCC68199.1 - 2.2e-07 31.4 0.0 0.00011 22.7 0.0 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 CCC68199.1 - 2.1e-06 27.7 0.1 6.8e-05 22.9 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CCC68199.1 - 1.4e-05 25.2 0.0 3.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCC68199.1 - 3.5e-05 23.6 0.0 7.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TsaE PF02367.17 CCC68199.1 - 0.00018 21.5 0.0 0.00031 20.7 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 CCC68199.1 - 0.0015 18.8 0.2 0.032 14.5 0.1 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCC68199.1 - 0.002 18.5 0.0 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.13 CCC68199.1 - 0.0026 17.0 0.0 0.0049 16.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Fib_alpha PF08702.10 CCC68199.1 - 0.0036 17.5 0.4 0.0083 16.3 0.4 1.6 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family AAA_18 PF13238.6 CCC68199.1 - 0.0057 17.2 0.0 0.028 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 CCC68199.1 - 0.0062 15.9 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CCC68199.1 - 0.0093 16.1 0.0 0.022 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CCC68199.1 - 0.012 15.4 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_24 PF13479.6 CCC68199.1 - 0.014 15.1 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 CCC68199.1 - 0.019 14.6 0.1 0.062 13.0 0.0 1.8 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 CCC68199.1 - 0.027 14.7 0.0 0.065 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CCC68199.1 - 0.03 14.4 0.0 0.083 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 CCC68199.1 - 0.037 13.4 1.3 0.1 11.9 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 CCC68199.1 - 0.039 13.5 1.5 0.19 11.3 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCC68199.1 - 0.046 13.2 0.0 0.12 11.9 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 CCC68199.1 - 0.061 12.8 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.6 CCC68199.1 - 0.066 13.0 1.0 0.94 9.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 CCC68199.1 - 0.076 12.1 0.1 0.16 11.1 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 CCC68199.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCC68199.1 - 0.13 11.9 0.2 0.58 9.9 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.12 CCC68199.1 - 0.18 11.7 0.1 0.5 10.3 0.1 1.8 1 1 0 1 1 1 0 NACHT domain HIT PF01230.23 CCC68200.1 - 3.2e-21 75.9 0.1 8e-21 74.6 0.1 1.6 2 0 0 2 2 2 1 HIT domain zf-C2HE PF16278.5 CCC68200.1 - 1.5e-15 57.3 1.8 3.2e-15 56.3 1.8 1.6 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger DcpS_C PF11969.8 CCC68200.1 - 4.5e-14 52.9 1.0 1.5e-13 51.2 1.0 1.8 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2H2_4 PF13894.6 CCC68200.1 - 0.0088 16.8 0.6 0.043 14.7 0.2 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger DUF1882 PF08966.11 CCC68200.1 - 0.53 10.6 3.7 1.2 9.4 1.6 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1882) TFR_dimer PF04253.15 CCC68201.1 - 2.2e-28 98.8 0.6 4.1e-28 97.9 0.6 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CCC68201.1 - 0.023 14.4 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M28 Rbsn PF11464.8 CCC68201.1 - 0.089 12.5 0.5 1.7 8.5 0.1 2.4 2 0 0 2 2 2 0 Rabenosyn Rab binding domain Acetyltransf_10 PF13673.7 CCC68202.1 - 5.8e-13 48.9 0.1 7.5e-13 48.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCC68202.1 - 9.2e-12 45.2 0.0 1.4e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCC68202.1 - 8.4e-09 35.7 0.2 1.4e-08 35.1 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCC68202.1 - 0.0028 17.6 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 CCC68202.1 - 0.0063 16.7 0.0 0.0073 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CCC68202.1 - 0.012 15.7 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_18 PF18014.1 CCC68202.1 - 0.058 13.2 0.0 0.08 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3780 PF12635.7 CCC68202.1 - 0.17 11.7 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3780) Tma16 PF11176.8 CCC68203.1 - 1.4e-46 158.0 2.5 1.7e-46 157.7 2.5 1.1 1 0 0 1 1 1 1 Translation machinery-associated protein 16 Rhodanese PF00581.20 CCC68204.1 - 3.9e-21 75.6 0.0 1.3e-09 38.6 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain ACP_syn_III_C PF08541.10 CCC68204.1 - 0.18 12.0 0.0 0.47 10.7 0.0 1.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal CLP1_P PF16575.5 CCC68205.1 - 1.4e-30 106.5 0.0 2.1e-30 105.9 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 CCC68205.1 - 5.1e-27 94.6 0.0 8.4e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 CCC68205.1 - 5.1e-23 81.1 0.0 9.3e-23 80.3 0.0 1.5 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_24 PF13479.6 CCC68205.1 - 6.1e-05 22.8 0.1 0.00037 20.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 CCC68205.1 - 0.00065 19.5 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_33 PF13671.6 CCC68205.1 - 0.0012 19.0 0.1 0.017 15.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.17 CCC68205.1 - 0.0045 16.8 0.1 0.013 15.3 0.0 1.7 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 CCC68205.1 - 0.0055 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 CCC68205.1 - 0.031 13.6 0.0 0.82 8.9 0.0 2.2 2 0 0 2 2 2 0 Septin AAA PF00004.29 CCC68205.1 - 0.058 13.8 0.1 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 CCC68205.1 - 0.086 13.1 0.0 0.24 11.7 0.0 1.8 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 CCC68205.1 - 0.092 13.1 0.0 0.32 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_7 PF12775.7 CCC68205.1 - 0.12 11.9 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region FeoB_N PF02421.18 CCC68205.1 - 0.12 11.9 0.5 0.31 10.5 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.6 CCC68205.1 - 0.13 12.5 0.1 1.8 8.8 0.0 2.5 3 1 0 3 3 2 0 AAA domain ANAPC5 PF12862.7 CCC68206.1 - 7.6e-26 90.0 5.4 7.6e-26 90.0 5.4 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 EKAL PF17986.1 CCC68206.1 - 0.66 10.0 3.7 2 8.5 1.0 2.7 2 0 0 2 2 2 0 EMP3-KAHRP-like N-terminal domain adh_short PF00106.25 CCC68209.1 - 8e-22 77.6 0.0 3.8e-11 42.8 0.0 3.0 2 1 1 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.6 CCC68209.1 - 3.4e-13 49.7 0.0 1.8e-10 40.8 0.0 2.6 2 1 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CCC68209.1 - 0.0017 17.8 0.1 0.003 17.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 CCC68209.1 - 0.002 18.0 0.0 0.0046 16.9 0.0 1.5 1 1 0 1 1 1 1 KR domain tRNA-synt_1 PF00133.22 CCC68210.1 - 4.5e-45 154.0 0.0 2.4e-35 121.9 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CCC68210.1 - 2.5e-17 62.8 0.4 1.3e-09 37.3 0.0 4.1 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CCC68210.1 - 9.5e-14 51.6 0.0 2.8e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CCC68210.1 - 5.8e-07 29.1 1.8 1.2e-06 28.1 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain MFA1_2 PF17317.2 CCC68211.1 - 1.1e-18 66.6 0.4 1.2e-18 66.5 0.4 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 YEATS PF03366.16 CCC68212.1 - 4.3e-20 71.5 0.0 6.9e-20 70.8 0.0 1.3 1 0 0 1 1 1 1 YEATS family BET PF17035.5 CCC68212.1 - 1.9e-05 24.8 0.1 4.9e-05 23.4 0.1 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Alpha_L_fucos PF01120.17 CCC68213.1 - 0.035 13.6 0.3 0.041 13.3 0.3 1.1 1 0 0 1 1 1 0 Alpha-L-fucosidase YqeY PF09424.10 CCC68214.1 - 9.9e-20 71.1 5.6 1.3e-19 70.7 5.6 1.1 1 0 0 1 1 1 1 Yqey-like protein FRB_dom PF08771.11 CCC68214.1 - 0.0035 17.7 2.9 0.0059 17.0 2.3 1.8 1 1 0 1 1 1 1 FKBP12-rapamycin binding domain DUF1098 PF06497.11 CCC68214.1 - 0.081 13.4 0.6 0.16 12.5 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) DUF5446 PF17522.2 CCC68214.1 - 0.4 10.9 5.4 7.6 6.8 0.1 2.6 2 1 0 2 2 2 0 Family of unknown function (DUF5446) TipAS PF07739.13 CCC68214.1 - 0.97 10.0 4.6 1.2 9.6 1.5 2.1 1 1 0 2 2 2 0 TipAS antibiotic-recognition domain GRAB PF10375.9 CCC68215.1 - 6.1e-07 29.1 1.6 1.4e-06 28.0 1.6 1.6 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Nup54 PF13874.6 CCC68215.1 - 0.0026 17.9 9.8 0.0026 17.9 9.8 4.4 1 1 3 4 4 4 1 Nucleoporin complex subunit 54 TACC_C PF05010.14 CCC68215.1 - 0.0027 17.5 23.2 0.0027 17.5 23.2 4.1 1 1 3 4 4 4 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal HMMR_N PF15905.5 CCC68215.1 - 0.0046 16.5 56.9 0.0046 16.5 56.9 3.1 1 1 2 3 3 3 1 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 CCC68215.1 - 0.0074 16.3 30.0 0.0074 16.3 30.0 5.0 1 1 4 5 5 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Jnk-SapK_ap_N PF09744.9 CCC68215.1 - 0.0091 16.2 11.2 0.0091 16.2 11.2 5.6 3 1 3 6 6 6 1 JNK_SAPK-associated protein-1 ATG16 PF08614.11 CCC68215.1 - 0.012 15.8 20.5 0.012 15.8 20.5 4.6 1 1 3 4 4 4 0 Autophagy protein 16 (ATG16) Bap31_Bap29_C PF18035.1 CCC68215.1 - 0.022 14.7 2.5 0.022 14.7 2.5 7.7 4 2 2 6 6 5 0 Bap31/Bap29 cytoplasmic coiled-coil domain bZIP_1 PF00170.21 CCC68215.1 - 0.033 14.3 2.6 0.033 14.3 2.6 8.1 3 1 5 9 9 7 0 bZIP transcription factor HALZ PF02183.18 CCC68215.1 - 0.27 11.5 0.2 0.27 11.5 0.2 7.5 6 2 1 7 7 7 0 Homeobox associated leucine zipper Golgin_A5 PF09787.9 CCC68215.1 - 1.4 8.4 86.2 0.013 15.0 26.8 3.6 1 1 3 4 4 4 0 Golgin subfamily A member 5 DUF1664 PF07889.12 CCC68215.1 - 1.5 8.9 54.6 0.29 11.2 9.2 5.2 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 CCC68215.1 - 3.1 7.1 55.2 0.97 8.7 15.4 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) Fib_alpha PF08702.10 CCC68215.1 - 3.1 8.0 66.4 0.021 15.0 22.6 4.5 2 2 2 4 4 3 0 Fibrinogen alpha/beta chain family GAS PF13851.6 CCC68215.1 - 5.1 6.4 97.7 0.29 10.4 20.8 5.1 1 1 4 5 5 5 0 Growth-arrest specific micro-tubule binding DASH_Dam1 PF08653.10 CCC68215.1 - 8.3 6.3 19.0 1.8 8.4 0.9 5.2 5 0 0 5 5 5 0 DASH complex subunit Dam1 RFC1 PF08519.12 CCC68216.1 - 1.3e-62 210.6 0.4 1.3e-62 210.6 0.4 2.2 3 0 0 3 3 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 CCC68216.1 - 1.8e-12 47.8 0.1 8e-12 45.7 0.0 2.2 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 CCC68216.1 - 1.6e-11 44.4 0.7 9.1e-11 42.0 0.0 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.15 CCC68216.1 - 1.6e-07 31.4 0.0 3.8e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 CCC68216.1 - 1.1e-05 25.2 0.0 3.1e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCC68216.1 - 7.6e-05 23.0 0.0 0.00039 20.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCC68216.1 - 0.00061 20.2 0.0 0.0037 17.6 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CCC68216.1 - 0.00076 19.7 0.0 0.0017 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 CCC68216.1 - 0.0013 19.1 2.1 0.0096 16.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCC68216.1 - 0.0022 18.5 0.0 0.0074 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 CCC68216.1 - 0.003 17.9 0.0 0.01 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain RNA_helicase PF00910.22 CCC68216.1 - 0.0034 17.7 0.0 0.012 16.0 0.0 2.0 1 0 0 1 1 1 1 RNA helicase SpoIIIAH PF12685.7 CCC68216.1 - 0.011 15.6 0.1 0.011 15.6 0.1 2.9 3 0 0 3 3 3 0 SpoIIIAH-like protein AAA_24 PF13479.6 CCC68216.1 - 0.011 15.5 0.1 0.039 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 CCC68216.1 - 0.03 14.3 0.0 0.12 12.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CCC68216.1 - 0.086 12.8 0.0 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 CCC68216.1 - 0.1 12.5 0.1 0.51 10.2 0.0 2.2 3 0 0 3 3 3 0 NTPase AAA_5 PF07728.14 CCC68216.1 - 0.14 12.2 0.0 0.46 10.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TPPK_C PF12555.8 CCC68217.1 - 0.043 13.9 0.1 0.069 13.2 0.1 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphokinase C terminal PH_15 PF17339.2 CCC68218.1 - 0.18 11.7 0.3 2.5 8.1 0.2 2.1 1 1 1 2 2 2 0 PH domain Acyl_transf_1 PF00698.21 CCC68219.1 - 0.094 12.2 0.0 0.69 9.4 0.0 2.0 2 0 0 2 2 2 0 Acyl transferase domain Mito_carr PF00153.27 CCC68220.1 - 1.6e-64 213.8 0.9 5.8e-24 83.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 CCC68220.1 - 0.046 14.1 0.4 0.23 11.9 0.4 2.4 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Sda PF08970.10 CCC68220.1 - 0.18 11.5 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 Sporulation inhibitor A DUF2407_C PF13373.6 CCC68221.1 - 5.3e-43 146.5 1.0 5.3e-43 146.5 1.0 1.7 2 0 0 2 2 2 1 DUF2407 C-terminal domain DUF2407 PF10302.9 CCC68221.1 - 2.4e-22 79.4 0.1 4e-22 78.8 0.1 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain SICA_alpha PF12887.7 CCC68221.1 - 0.038 13.9 0.0 0.39 10.6 0.0 2.1 2 0 0 2 2 2 0 SICA extracellular alpha domain TMEM240 PF15207.6 CCC68221.1 - 0.099 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 TMEM240 family RNA_pol_Rpb8 PF03870.15 CCC68222.1 - 2.5e-46 157.3 0.0 2.8e-46 157.2 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 CCC68222.1 - 5.2e-05 23.3 0.5 0.035 14.2 0.1 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G NifU_N PF01592.16 CCC68223.1 - 3.7e-55 185.5 0.2 4.4e-55 185.3 0.2 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 CCC68223.1 - 0.0028 17.9 0.2 0.0055 16.9 0.2 1.4 1 0 0 1 1 1 1 TSCPD domain LRRFIP PF09738.9 CCC68224.1 - 0.0055 16.2 1.2 0.0055 16.2 1.2 3.6 4 1 0 4 4 4 1 LRRFIP family LRR_4 PF12799.7 CCC68224.1 - 0.028 14.8 16.3 0.12 12.8 3.8 5.7 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) OrfB_IS605 PF01385.19 CCC68224.1 - 0.063 13.5 2.0 0.19 12.0 2.0 1.8 1 0 0 1 1 1 0 Probable transposase DUF3340 PF11818.8 CCC68224.1 - 0.07 13.3 4.3 0.34 11.1 4.3 2.2 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) DUF1896 PF08989.10 CCC68224.1 - 0.23 11.6 3.1 2.9 8.0 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1896) DUF1691 PF07950.11 CCC68225.1 - 1.7e-15 57.6 5.4 6e-07 30.2 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.22 CCC68225.1 - 0.005 16.9 4.9 0.016 15.2 1.8 2.2 2 0 0 2 2 2 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Tam41_Mmp37 PF09139.11 CCC68226.1 - 1.3e-93 314.0 4.8 9.8e-86 288.1 0.4 2.1 1 1 1 2 2 2 2 Phosphatidate cytidylyltransferase, mitochondrial WD40 PF00400.32 CCC68227.1 - 2.7e-05 24.8 10.6 0.014 16.2 0.5 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40 PF00400.32 CCC68228.1 - 5.7e-06 27.0 8.7 0.019 15.8 0.2 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat Pkinase PF00069.25 CCC68229.1 - 1.3e-72 244.4 0.0 1.7e-72 243.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68229.1 - 6.6e-35 120.6 0.0 1.3e-34 119.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC68229.1 - 3.8e-08 33.0 0.0 6.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCC68229.1 - 0.0011 17.9 0.0 0.0018 17.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 CCC68229.1 - 0.0017 18.1 0.3 0.8 9.3 0.0 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CCC68229.1 - 0.008 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CCC68229.1 - 0.016 14.2 0.1 0.028 13.4 0.1 1.5 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CCC68229.1 - 0.017 15.0 0.0 0.096 12.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CCC68229.1 - 0.028 13.5 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 GrpE PF01025.19 CCC68230.1 - 2.4e-48 163.9 10.4 3e-48 163.6 10.4 1.1 1 0 0 1 1 1 1 GrpE Uds1 PF15456.6 CCC68230.1 - 0.0005 20.2 5.1 0.00092 19.4 5.1 1.5 1 0 0 1 1 1 1 Up-regulated During Septation TACC_C PF05010.14 CCC68230.1 - 0.0034 17.2 14.5 0.062 13.1 0.2 2.1 2 0 0 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Exonuc_VII_L PF02601.15 CCC68230.1 - 0.0046 16.6 4.2 0.0056 16.3 4.2 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit PKcGMP_CC PF16808.5 CCC68230.1 - 0.017 15.0 2.9 0.017 15.0 2.9 2.0 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase OmpH PF03938.14 CCC68230.1 - 0.36 11.2 15.8 0.43 10.9 15.3 1.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin_2 PF14523.6 CCC68230.1 - 1.4 9.3 11.3 3.2 8.2 11.3 1.6 1 1 0 1 1 1 0 Syntaxin-like protein Pkinase PF00069.25 CCC68231.1 - 9.4e-64 215.3 0.0 1.8e-63 214.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68231.1 - 7.4e-39 133.6 0.0 1.3e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC68231.1 - 5.7e-09 35.7 0.0 1e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCC68231.1 - 0.0058 16.0 0.1 0.014 14.7 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CCC68231.1 - 0.0061 16.2 0.0 0.023 14.3 0.0 2.0 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CCC68231.1 - 0.0086 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 CCC68231.1 - 0.3 10.7 2.3 0.83 9.2 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ribosomal_L35Ae PF01247.18 CCC68232.1 - 1e-41 141.0 0.7 1.1e-41 140.8 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CCC68232.1 - 0.0073 16.5 0.0 3.8 7.8 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain POC3_POC4 PF10448.9 CCC68233.1 - 3e-15 56.5 1.3 3.5e-15 56.3 1.3 1.1 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 PAC4 PF16093.5 CCC68233.1 - 1.4e-06 28.4 0.0 3.7e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 DHFR_1 PF00186.19 CCC68234.1 - 5e-28 97.8 0.0 8.6e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase Trm56 PF01994.16 CCC68234.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 Oxysterol_BP PF01237.18 CCC68235.1 - 5.5e-54 183.4 2.1 8.5e-48 163.1 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein MA3 PF02847.17 CCC68236.1 - 0.0099 15.8 0.2 0.02 14.9 0.2 1.5 1 0 0 1 1 1 1 MA3 domain ABC_membrane_2 PF06472.15 CCC68237.1 - 2.6e-81 273.0 4.4 4e-81 272.4 4.4 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 CCC68237.1 - 1.7e-13 51.3 0.0 5.5e-13 49.6 0.0 1.9 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CCC68237.1 - 0.005 16.3 0.0 0.051 13.0 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain bPH_3 PF14470.6 CCC68237.1 - 0.12 12.8 2.2 9.4 6.7 0.2 2.9 3 0 0 3 3 3 0 Bacterial PH domain SbcCD_C PF13558.6 CCC68237.1 - 0.17 12.1 0.3 1.3 9.3 0.3 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_23 PF13476.6 CCC68237.1 - 1.2 9.6 4.1 11 6.5 4.1 2.4 1 1 0 1 1 1 0 AAA domain DUF1749 PF08538.10 CCC68238.1 - 1.8e-94 316.2 0.0 2e-94 316.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 CCC68238.1 - 2.4e-07 30.3 0.0 4e-06 26.3 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CCC68238.1 - 0.0014 18.1 0.0 0.0046 16.4 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ndr PF03096.14 CCC68238.1 - 0.0022 16.8 0.0 0.003 16.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.13 CCC68238.1 - 0.0051 16.7 0.0 0.0082 16.0 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase LIDHydrolase PF10230.9 CCC68238.1 - 0.0096 15.5 0.4 0.025 14.1 0.2 1.7 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_1 PF00561.20 CCC68238.1 - 0.014 15.0 0.0 0.069 12.8 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold SPA PF08616.10 CCC68238.1 - 0.029 14.3 0.0 0.049 13.6 0.0 1.5 1 0 0 1 1 1 0 Stabilization of polarity axis Abhydrolase_6 PF12697.7 CCC68238.1 - 0.056 14.0 0.0 0.087 13.4 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 CCC68238.1 - 0.067 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF900 PF05990.12 CCC68238.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DLH PF01738.18 CCC68238.1 - 0.14 11.7 0.0 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family DASH_Duo1 PF08651.10 CCC68240.1 - 0.066 13.0 7.2 0.21 11.4 1.7 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF2023 PF09633.10 CCC68240.1 - 0.15 12.2 2.0 3.4 7.9 0.1 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2023) DUF4209 PF13910.6 CCC68240.1 - 0.56 10.5 3.3 9.9 6.5 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4209) Mur_ligase_M PF08245.12 CCC68243.1 - 1.1e-05 25.5 1.5 7.6e-05 22.8 0.0 2.8 2 1 1 3 3 3 1 Mur ligase middle domain Mur_ligase_C PF02875.21 CCC68243.1 - 0.036 14.3 0.0 0.077 13.3 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain TruD PF01142.18 CCC68245.1 - 1.7e-72 244.6 0.2 2.5e-66 224.2 0.0 3.5 3 1 0 3 3 3 3 tRNA pseudouridine synthase D (TruD) LPD3 PF18798.1 CCC68245.1 - 0.031 14.5 1.5 8.4 6.7 0.1 2.9 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 3 NifW PF03206.14 CCC68245.1 - 0.28 11.7 2.6 0.71 10.4 0.9 2.3 2 0 0 2 2 2 0 Nitrogen fixation protein NifW MOZ_SAS PF01853.18 CCC68246.1 - 4.7e-82 274.0 0.2 7.1e-82 273.4 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.8 CCC68246.1 - 6.3e-22 77.2 0.2 1.3e-21 76.2 0.2 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain zf-MYST PF17772.1 CCC68246.1 - 1.1e-20 72.9 0.2 3.2e-20 71.5 0.2 1.8 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CCC68246.1 - 0.0014 19.0 0.0 0.0041 17.5 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCC68246.1 - 0.0028 17.9 0.0 0.015 15.5 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DAGAT PF03982.13 CCC68247.1 - 4.6e-83 278.5 1.9 3e-72 243.1 0.1 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Rer1 PF03248.13 CCC68247.1 - 0.0055 16.5 0.2 0.045 13.5 0.1 2.1 2 0 0 2 2 2 1 Rer1 family Glutaredoxin PF00462.24 CCC68248.1 - 0.018 15.3 0.0 0.042 14.1 0.0 1.7 2 0 0 2 2 2 0 Glutaredoxin YEATS PF03366.16 CCC68249.1 - 7.7e-18 64.3 0.0 1.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 YEATS family WD40 PF00400.32 CCC68250.1 - 1.3e-29 101.8 20.8 2.5e-06 28.1 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC68250.1 - 1e-10 41.8 0.1 0.23 11.8 0.0 4.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCC68250.1 - 0.019 14.3 2.4 1.1 8.5 0.0 2.9 4 0 0 4 4 4 0 WD40-like domain Dynamin_N PF00350.23 CCC68251.1 - 8.2e-44 149.6 0.2 3.7e-43 147.5 0.2 2.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 CCC68251.1 - 1.6e-05 25.0 0.2 0.00019 21.5 0.2 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.20 CCC68251.1 - 0.0073 15.6 0.1 0.0073 15.6 0.1 3.1 2 1 0 2 2 2 1 Dynamin central region AAA_16 PF13191.6 CCC68251.1 - 0.04 14.3 0.3 0.22 11.9 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CCC68251.1 - 0.066 13.4 0.0 0.23 11.7 0.0 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DUF1140 PF06600.11 CCC68251.1 - 0.36 11.3 4.1 7.2 7.1 0.6 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1140) RNA_pol_N PF01194.17 CCC68252.1 - 9.5e-30 102.7 0.5 1.1e-29 102.5 0.5 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.12 CCC68252.1 - 0.059 13.6 0.2 0.079 13.2 0.2 1.3 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) NAPRTase PF04095.16 CCC68253.1 - 3.3e-67 226.6 0.0 4.2e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CCC68253.1 - 1.6e-33 115.7 1.7 2.8e-33 115.0 1.7 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain RNA_pol_Rpb2_6 PF00562.28 CCC68254.1 - 2.8e-126 421.7 0.5 5.1e-126 420.9 0.5 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CCC68254.1 - 5.1e-62 209.0 2.7 6.2e-62 208.7 1.3 1.8 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CCC68254.1 - 1.2e-41 142.5 2.8 3e-41 141.2 2.8 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CCC68254.1 - 6.7e-34 116.2 0.3 2.1e-33 114.6 0.3 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CCC68254.1 - 1.3e-26 92.6 0.2 4.5e-26 90.9 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CCC68254.1 - 1.7e-18 66.6 0.2 4.4e-18 65.2 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CCC68254.1 - 4.2e-11 43.2 0.2 2e-10 41.1 0.2 2.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Noc2 PF03715.13 CCC68255.1 - 1e-128 428.8 5.6 1e-128 428.8 5.6 2.1 2 0 0 2 2 2 1 Noc2p family Nop14 PF04147.12 CCC68255.1 - 0.00019 19.8 0.7 0.00019 19.8 0.7 3.2 2 1 0 3 3 3 1 Nop14-like family MMR_HSR1 PF01926.23 CCC68256.1 - 7.7e-09 35.6 0.2 4.8e-08 33.1 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCC68256.1 - 2.7e-07 30.6 0.0 5.8e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 CCC68256.1 - 0.0036 16.8 0.2 0.018 14.5 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CCC68256.1 - 0.0043 17.1 1.4 0.42 10.7 0.1 3.3 2 1 1 3 3 3 1 Dynamin family ABC_tran PF00005.27 CCC68256.1 - 0.0086 16.6 0.1 0.019 15.5 0.1 1.5 1 0 0 1 1 1 1 ABC transporter GTP_EFTU PF00009.27 CCC68256.1 - 0.011 15.3 0.3 1.6 8.2 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CCC68256.1 - 0.02 14.6 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Roc PF08477.13 CCC68256.1 - 0.09 13.0 0.1 0.27 11.5 0.1 1.9 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase DEAD PF00270.29 CCC68257.1 - 1.7e-49 168.0 0.0 5.7e-49 166.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC68257.1 - 2.2e-32 111.7 0.0 5.4e-32 110.4 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CCC68257.1 - 0.0093 15.2 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CCC68257.1 - 0.068 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit IGPD PF00475.18 CCC68258.1 - 2.1e-60 203.2 0.4 5.8e-60 201.8 0.5 1.6 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase DUF3943 PF13084.6 CCC68258.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3943) SpoU_methylase PF00588.19 CCC68259.1 - 1.9e-25 89.7 0.0 3.1e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 CCC68259.1 - 6.9e-15 55.1 0.0 1.2e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding DUF2730 PF10805.8 CCC68260.1 - 5 7.3 25.5 2.2 8.4 0.9 5.3 3 1 2 5 5 5 0 Protein of unknown function (DUF2730) Peptidase_C14 PF00656.22 CCC68261.1 - 1.3e-64 218.6 0.1 1.6e-64 218.2 0.1 1.1 1 0 0 1 1 1 1 Caspase domain LIAS_N PF16881.5 CCC68262.1 - 2.3e-19 69.8 0.1 4.8e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 CCC68262.1 - 8.1e-13 49.1 0.0 1.7e-12 48.1 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.11 CCC68262.1 - 0.036 14.3 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal WBP-1 PF11669.8 CCC68263.1 - 0.015 15.9 0.9 0.55 10.9 0.1 2.4 2 0 0 2 2 2 0 WW domain-binding protein 1 TMEM132D_C PF15706.5 CCC68263.1 - 0.13 12.1 1.0 13 5.6 0.1 2.5 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term CdiA_C PF18451.1 CCC68263.1 - 0.18 12.0 0.2 7.8 6.8 0.1 2.2 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain Fungal_TACC PF12709.7 CCC68264.1 - 6.7e-32 109.8 12.7 6.7e-32 109.8 12.7 10.5 2 1 8 11 11 11 2 Fungal Transforming acidic coiled-coil (TACC) proteins Spc7 PF08317.11 CCC68264.1 - 0.00064 18.7 24.9 0.00064 18.7 24.9 5.3 1 1 4 5 5 5 4 Spc7 kinetochore protein DUF4472 PF14739.6 CCC68264.1 - 0.021 15.6 3.0 0.021 15.6 3.0 7.9 2 2 6 8 8 8 0 Domain of unknown function (DUF4472) Filament PF00038.21 CCC68264.1 - 9.5 5.7 95.5 0.32 10.5 40.6 4.5 1 1 2 3 3 3 0 Intermediate filament protein PEX11 PF05648.14 CCC68265.1 - 4.2e-06 26.4 2.9 1.5e-05 24.6 2.9 1.9 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PDH PF02153.17 CCC68267.1 - 1.4e-08 34.0 0.0 2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.19 CCC68267.1 - 0.00034 20.0 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 CCC68267.1 - 0.0022 18.5 0.0 0.0043 17.6 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 CCC68267.1 - 0.0031 17.7 0.0 0.0052 17.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 CCC68267.1 - 0.0061 16.2 0.0 0.013 15.2 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 CCC68267.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 CCC68267.1 - 0.046 13.3 0.0 0.082 12.5 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 CCC68267.1 - 0.17 11.4 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Rpp20 PF12328.8 CCC68268.1 - 3.4e-29 101.5 5.0 8.9e-27 93.7 5.0 2.1 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.21 CCC68268.1 - 6.3e-11 41.9 0.1 9.8e-11 41.3 0.1 1.4 1 0 0 1 1 1 1 Alba Pex24p PF06398.11 CCC68269.1 - 1e-39 136.6 17.3 1.3e-39 136.3 17.3 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HSP70 PF00012.20 CCC68270.1 - 7.8e-181 602.3 3.6 7.8e-181 602.3 3.6 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 CCC68270.1 - 2.8e-10 39.5 0.1 5.2e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.6 CCC68270.1 - 0.012 16.0 0.1 0.012 16.0 0.1 3.3 3 2 0 3 3 3 0 Cell division protein FtsA Trans_reg_C PF00486.28 CCC68270.1 - 0.039 14.0 0.1 0.15 12.1 0.0 2.0 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal CT_C_D PF02682.16 CCC68270.1 - 0.14 11.9 0.0 0.45 10.2 0.0 1.9 1 0 0 1 1 1 0 Carboxyltransferase domain, subdomain C and D Ribosomal_60s PF00428.19 CCC68270.1 - 3.7 8.2 17.7 3.5 8.3 14.4 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein NPL4 PF05021.15 CCC68271.1 - 1.5e-136 454.8 0.0 1.9e-136 454.4 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 CCC68271.1 - 3e-70 235.0 0.8 4.6e-70 234.4 0.8 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 CCC68271.1 - 7.1e-07 29.6 0.0 2.5e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.9 CCC68272.1 - 2.3e-69 232.6 2.2 2.6e-69 232.4 2.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 TMEM154 PF15102.6 CCC68272.1 - 0.008 16.1 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 TMEM154 protein family Tubulin_3 PF14881.6 CCC68272.1 - 0.061 13.0 0.1 0.15 11.8 0.0 1.5 1 1 0 1 1 1 0 Tubulin domain GYF PF02213.16 CCC68273.1 - 6.3e-14 51.4 0.1 1.2e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 GYF domain Asp-B-Hydro_N PF05279.11 CCC68273.1 - 1 9.4 26.6 1.4 8.9 26.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Pyrid_oxidase_2 PF13883.6 CCC68273.1 - 1.2 9.0 7.4 0.059 13.3 1.2 1.9 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase UMP1 PF05348.11 CCC68274.1 - 2.8e-42 143.7 0.5 3.4e-42 143.4 0.5 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 WD40 PF00400.32 CCC68275.1 - 1.9e-28 98.1 14.3 2.4e-05 25.0 0.4 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC68275.1 - 2.5e-21 75.8 0.0 0.00023 21.4 0.0 5.1 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 CCC68275.1 - 7e-05 22.7 0.0 3.7 7.6 0.0 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Ge1_WD40 PF16529.5 CCC68275.1 - 0.00015 20.8 1.7 1.8 7.4 0.0 3.9 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 CCC68275.1 - 0.00045 19.4 0.0 0.0087 15.1 0.0 2.8 2 1 1 4 4 4 1 Coatomer WD associated region Cytochrom_D1 PF02239.16 CCC68275.1 - 0.0066 15.0 0.0 2.4 6.6 0.0 2.3 1 1 1 2 2 2 2 Cytochrome D1 heme domain RAB3GAP2_N PF14655.6 CCC68275.1 - 0.011 15.0 0.3 21 4.2 0.0 3.7 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nup160 PF11715.8 CCC68275.1 - 0.027 13.1 0.1 0.49 9.0 0.1 2.7 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Hira PF07569.11 CCC68275.1 - 0.031 14.0 3.8 5.6 6.6 0.0 3.5 3 1 1 4 4 4 0 TUP1-like enhancer of split B_lectin PF01453.24 CCC68275.1 - 0.11 13.0 0.0 13 6.4 0.0 2.5 2 0 0 2 2 2 0 D-mannose binding lectin Pantoate_transf PF02548.15 CCC68276.1 - 3.8e-94 314.9 0.1 4.5e-94 314.7 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 CCC68276.1 - 5.5e-05 22.7 0.0 9.1e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.22 CCC68276.1 - 0.0011 18.9 0.0 0.0021 17.9 0.0 1.5 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase UPF0014 PF03649.13 CCC68276.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) PAXNEB PF05625.11 CCC68277.1 - 5.4e-91 305.5 0.1 7.6e-91 305.0 0.1 1.2 1 0 0 1 1 1 1 PAXNEB protein Romo1 PF10247.9 CCC68278.1 - 7e-27 93.6 11.3 8.8e-27 93.3 11.3 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 tRNA-synt_1b PF00579.25 CCC68279.1 - 2.3e-77 260.2 0.0 3.4e-77 259.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Radical_SAM_N PF08497.10 CCC68279.1 - 0.15 11.2 0.0 0.26 10.5 0.0 1.3 1 0 0 1 1 1 0 Radical SAM N-terminal TyrRSs_C PF16714.5 CCC68279.1 - 0.16 11.8 0.5 2.5 7.9 0.5 2.3 1 1 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain DUF5418 PF17439.2 CCC68280.1 - 0.00037 20.6 2.6 0.00039 20.5 2.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5418) BatD PF13584.6 CCC68280.1 - 0.04 12.7 0.5 0.04 12.8 0.5 1.1 1 0 0 1 1 1 0 Oxygen tolerance PIG-Y PF15159.6 CCC68280.1 - 0.28 12.1 12.9 0.48 11.4 12.9 1.4 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Phlebovirus_G1 PF07243.11 CCC68280.1 - 1.4 7.2 2.8 1.5 7.1 2.8 1.0 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Novirhabdo_Nv PF05554.11 CCC68281.1 - 0.043 13.6 0.3 0.38 10.5 0.0 2.1 2 0 0 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein Abhydrolase_1 PF00561.20 CCC68282.1 - 4.5e-27 95.3 0.0 8.1e-27 94.5 0.0 1.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCC68282.1 - 3.4e-12 46.1 0.0 8.8e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCC68282.1 - 3.6e-05 24.5 0.0 6.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 CCC68282.1 - 0.0051 16.3 0.0 0.0083 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Peptidase_S9 PF00326.21 CCC68282.1 - 0.029 13.8 0.0 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Palm_thioest PF02089.15 CCC68282.1 - 0.032 14.1 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Cutinase PF01083.22 CCC68282.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Cutinase Dynamin_N PF00350.23 CCC68283.1 - 2e-17 63.7 0.5 2e-17 63.7 0.5 2.8 4 0 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.23 CCC68283.1 - 1.3e-08 34.9 3.0 3.5e-08 33.5 0.5 3.2 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCC68283.1 - 2.3e-07 30.6 0.0 3.3e-05 23.5 0.0 2.7 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RNR_N PF08343.10 CCC68283.1 - 0.01 15.8 0.5 0.075 13.1 0.0 2.6 2 0 0 2 2 2 0 Ribonucleotide reductase N-terminal PPV_E1_C PF00519.17 CCC68283.1 - 0.018 13.9 0.2 0.042 12.7 0.1 1.5 1 1 0 1 1 1 0 Papillomavirus helicase CDT1 PF08839.11 CCC68283.1 - 0.028 14.7 2.8 1.7 8.9 0.3 2.9 2 1 0 2 2 2 0 DNA replication factor CDT1 like AAA_18 PF13238.6 CCC68283.1 - 0.29 11.7 2.0 3.3 8.3 0.0 3.6 4 0 0 4 4 4 0 AAA domain NOG1_N PF17835.1 CCC68284.1 - 4.5e-50 169.7 3.8 2.8e-49 167.1 0.1 2.6 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOGCT PF08155.11 CCC68284.1 - 2.5e-26 91.4 2.6 2.5e-26 91.4 2.6 1.9 2 0 0 2 2 2 1 NOGCT (NUC087) domain NOG1 PF06858.14 CCC68284.1 - 8.1e-26 89.6 0.2 2.4e-25 88.1 0.2 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 CCC68284.1 - 2.2e-16 59.9 0.0 1.2e-15 57.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCC68284.1 - 1.9e-07 30.7 0.0 4.8e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 CCC68284.1 - 0.0021 17.4 0.3 0.011 15.1 0.0 2.2 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CCC68284.1 - 0.005 16.8 0.0 1.9 8.4 0.1 2.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CCC68284.1 - 0.01 16.2 0.0 0.29 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain Dynamin_N PF00350.23 CCC68284.1 - 0.029 14.4 0.0 6.4 6.8 0.0 2.9 1 1 1 2 2 2 0 Dynamin family PRAS PF15798.5 CCC68284.1 - 0.049 14.2 0.6 0.098 13.2 0.6 1.5 1 0 0 1 1 1 0 Proline-rich AKT1 substrate 1 Roc PF08477.13 CCC68284.1 - 0.094 12.9 0.0 0.44 10.8 0.0 2.2 2 1 0 2 2 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 CCC68284.1 - 0.14 11.9 0.0 19 5.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain RisS_PPD PF16524.5 CCC68284.1 - 0.18 12.1 0.5 0.55 10.5 0.5 1.8 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS MFS_1 PF07690.16 CCC68285.1 - 5.1e-48 163.8 24.7 5.1e-48 163.8 24.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC68285.1 - 2e-19 69.8 3.5 2e-19 69.8 3.5 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 CCC68285.1 - 0.00054 19.4 7.9 0.00054 19.4 7.9 2.9 3 0 0 3 3 3 2 Uncharacterised MFS-type transporter YbfB Ribosomal_S6e PF01092.19 CCC68286.1 - 2e-22 79.5 0.8 4.4e-22 78.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e SRF-TF PF00319.18 CCC68287.1 - 2.2e-20 71.9 0.1 3.5e-20 71.2 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ceramidase PF05875.12 CCC68288.1 - 2.8e-87 292.5 12.4 3.3e-87 292.3 12.4 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.11 CCC68288.1 - 2.7 8.2 6.0 0.46 10.6 1.4 2.2 2 0 0 2 2 2 0 Trp-operon Leader Peptide Radical_SAM_C PF16199.5 CCC68289.1 - 1.7e-32 111.3 0.0 3.2e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 CCC68289.1 - 4.2e-17 63.0 0.6 1.8e-16 61.0 0.1 2.2 3 0 0 3 3 3 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 CCC68289.1 - 1.3e-10 41.5 0.1 2.4e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCC68289.1 - 4.5e-06 26.6 0.0 1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCC68289.1 - 0.015 15.7 0.1 0.029 14.8 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MBA1 PF07961.11 CCC68291.1 - 1.8e-95 318.5 0.2 2.3e-95 318.1 0.2 1.0 1 0 0 1 1 1 1 MBA1-like protein Glyco_transf_20 PF00982.21 CCC68291.1 - 0.037 12.7 0.0 0.051 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 20 BRO1 PF03097.18 CCC68292.1 - 2.7e-93 312.9 9.7 4.4e-93 312.2 9.7 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 CCC68292.1 - 9.5e-23 80.9 7.7 9.5e-23 80.9 7.7 2.2 1 1 1 2 2 2 1 ALIX V-shaped domain binding to HIV DUF4559 PF15112.6 CCC68292.1 - 10 5.7 8.4 4.9 6.7 1.5 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) tRNA_int_end_N2 PF12928.7 CCC68293.1 - 9.1e-15 54.6 0.0 1.6e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term UPF0016 PF01169.19 CCC68294.1 - 9.9e-39 131.5 18.5 2e-19 69.7 3.4 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 cwf18 PF08315.12 CCC68295.1 - 6.3e-08 33.4 9.7 8e-08 33.0 9.7 1.1 1 0 0 1 1 1 1 cwf18 pre-mRNA splicing factor S4 PF01479.25 CCC68296.1 - 3.3e-13 49.1 0.2 1.2e-12 47.3 0.2 2.0 1 0 0 1 1 1 1 S4 domain Ribosomal_L21e PF01157.18 CCC68297.1 - 2.7e-48 162.0 4.6 2.7e-48 162.0 4.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.9 CCC68297.1 - 0.0027 17.3 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Mito_carr PF00153.27 CCC68298.1 - 4e-75 247.8 3.1 7.5e-28 96.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Phage_lysozyme2 PF18013.1 CCC68298.1 - 0.1 12.6 0.8 0.91 9.5 0.8 2.5 1 1 0 1 1 1 0 Phage tail lysozyme DUF2680 PF10925.8 CCC68298.1 - 0.13 12.3 0.1 0.28 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2680) Med8 PF10232.9 CCC68299.1 - 1.2e-16 61.0 2.6 1.5e-16 60.7 2.6 1.1 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 NPV_P10 PF05531.12 CCC68299.1 - 0.0024 18.3 1.2 0.14 12.7 0.1 2.6 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein ArAE_2 PF10334.9 CCC68299.1 - 0.0067 16.3 0.1 0.0096 15.8 0.1 1.2 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 DUF3078 PF11276.8 CCC68299.1 - 0.024 15.0 0.7 0.044 14.2 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3078) NpwBP PF12622.7 CCC68300.1 - 3.8e-09 37.2 1.6 4.8e-09 36.8 0.4 1.8 2 0 0 2 2 2 1 mRNA biogenesis factor Tox-REase-9 PF15650.6 CCC68300.1 - 0.2 12.0 1.1 0.34 11.2 0.9 1.4 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 9 CAF1C_H4-bd PF12265.8 CCC68301.1 - 5.3e-17 61.8 0.6 1.6e-16 60.3 0.6 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CCC68301.1 - 3.3e-12 46.7 18.3 0.0008 20.2 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat eIF2A PF08662.11 CCC68301.1 - 8.3e-09 35.6 0.1 2.9e-05 24.0 0.0 3.0 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 CCC68301.1 - 2e-08 34.4 2.3 0.07 13.4 0.1 5.0 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ovate PF04844.13 CCC68301.1 - 0.15 12.1 0.1 1 9.4 0.0 2.3 1 1 1 2 2 2 0 Transcriptional repressor, ovate PGI PF00342.19 CCC68302.1 - 6.1e-247 819.9 4.5 7.2e-247 819.7 4.5 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF5315 PF17242.2 CCC68303.1 - 7.5e-20 70.5 0.5 1.4e-19 69.7 0.5 1.4 1 0 0 1 1 1 1 Disordered region of unknown function (DUF5315) RBR PF17208.3 CCC68303.1 - 2.3 9.0 10.9 29 5.5 11.0 2.5 1 1 1 2 2 2 0 RNA binding Region WD40 PF00400.32 CCC68304.1 - 5e-52 172.7 20.4 1.6e-09 38.2 0.4 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 CCC68304.1 - 1.3e-41 141.8 0.5 2.3e-41 141.1 0.5 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 CCC68304.1 - 4.4e-13 49.3 0.1 0.14 12.5 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain LisH PF08513.11 CCC68304.1 - 7.1e-07 29.0 0.1 2.2e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 CCC68304.1 - 8.3e-06 25.0 0.0 0.024 13.6 0.0 3.8 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCC68304.1 - 1.5e-05 24.5 0.0 1 8.6 0.0 4.3 3 2 1 4 4 4 2 WD40-like domain Nup160 PF11715.8 CCC68304.1 - 0.0024 16.6 0.7 2.1 6.9 0.1 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 ELYS-bb PF16687.5 CCC68304.1 - 0.022 13.4 0.0 1.3 7.5 0.0 2.7 2 1 1 3 3 3 0 beta-propeller of ELYS nucleoporin nos_propeller PF18764.1 CCC68304.1 - 0.034 14.0 0.0 15 5.5 0.0 3.3 3 0 0 3 3 3 0 Nitrous oxide reductase propeller repeat Frtz PF11768.8 CCC68304.1 - 0.038 12.3 0.0 1.6 6.9 0.0 2.2 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz PD40 PF07676.12 CCC68304.1 - 0.053 13.5 0.0 4.8 7.3 0.0 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Peptidase_S30 PF01577.16 CCC68304.1 - 9.2 5.8 8.3 62 3.1 5.7 2.3 2 0 0 2 2 2 0 Potyvirus P1 protease Glyco_transf_15 PF01793.16 CCC68305.1 - 5.6e-105 351.2 13.2 7.5e-105 350.8 13.2 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase zf-HYPF PF07503.12 CCC68305.1 - 0.34 10.7 4.4 3.9 7.3 1.9 2.5 2 0 0 2 2 2 0 HypF finger SH3_1 PF00018.28 CCC68306.1 - 1.2e-24 85.6 0.0 1.2e-11 44.0 0.0 2.5 2 0 0 2 2 2 2 SH3 domain PX PF00787.24 CCC68306.1 - 4.6e-15 55.6 0.0 1.6e-14 53.8 0.0 2.0 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.6 CCC68306.1 - 4e-13 49.0 0.2 1.5e-09 37.5 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.17 CCC68306.1 - 3.2e-08 33.1 0.1 1.7e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain PB1 PF00564.24 CCC68306.1 - 9.6e-07 28.7 0.4 1.9e-06 27.7 0.4 1.5 1 0 0 1 1 1 1 PB1 domain USP7_ICP0_bdg PF12436.8 CCC68306.1 - 0.056 12.8 0.5 0.099 11.9 0.5 1.3 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 DER1 PF04511.15 CCC68307.1 - 3.2e-37 128.3 13.1 3.6e-37 128.2 13.1 1.0 1 0 0 1 1 1 1 Der1-like family MCM PF00493.23 CCC68308.1 - 1.2e-103 345.1 0.0 1.7e-103 344.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCC68308.1 - 1.7e-31 108.7 0.2 2.9e-31 107.9 0.2 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCC68308.1 - 1.7e-20 73.2 0.3 4.3e-20 71.9 0.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCC68308.1 - 2.2e-16 60.3 2.4 4.5e-16 59.3 0.8 2.4 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCC68308.1 - 1e-07 31.6 0.1 1.6e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCC68308.1 - 1.4e-06 28.3 0.0 1.5e-05 25.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_C PF13335.6 CCC68308.1 - 0.00036 21.1 0.1 0.0018 18.9 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI C-terminal AAA_lid_2 PF17863.1 CCC68308.1 - 0.035 13.9 0.0 0.089 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA lid domain Sigma54_activat PF00158.26 CCC68308.1 - 0.045 13.5 0.0 0.65 9.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 CCC68308.1 - 0.052 13.4 0.0 0.18 11.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCC68308.1 - 0.1 13.0 0.3 3.5 8.0 0.0 3.0 3 1 0 4 4 4 0 AAA ATPase domain F-box-like PF12937.7 CCC68309.1 - 0.016 15.1 0.0 0.036 14.0 0.0 1.7 1 0 0 1 1 1 0 F-box-like MTBP_mid PF14919.6 CCC68309.1 - 0.047 12.9 0.4 0.099 11.8 0.4 1.4 1 0 0 1 1 1 0 MDM2-binding ECSIT_C PF14784.6 CCC68309.1 - 0.094 13.1 0.0 0.43 10.9 0.0 2.1 1 0 0 1 1 1 0 C-terminal domain of the ECSIT protein Abhydrolase_1 PF00561.20 CCC68310.1 - 5.6e-19 68.8 0.1 8.3e-19 68.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCC68310.1 - 9.3e-17 61.1 0.0 8.9e-11 41.5 0.0 2.0 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCC68310.1 - 4.2e-16 60.2 0.0 5.1e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 CCC68310.1 - 4.9e-06 26.3 0.1 1.3e-05 24.9 0.1 1.7 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Ser_hydrolase PF06821.13 CCC68310.1 - 0.002 18.0 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.13 CCC68310.1 - 0.01 15.5 0.1 0.57 9.9 0.0 2.6 3 0 0 3 3 3 0 PGAP1-like protein FSH1 PF03959.13 CCC68310.1 - 0.048 13.3 0.0 0.31 10.7 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF1749 PF08538.10 CCC68310.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Glyco_transf_15 PF01793.16 CCC68311.1 - 8.7e-121 403.1 9.0 1.1e-120 402.7 9.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Amidase PF01425.21 CCC68312.1 - 1.9e-96 323.8 0.0 2.8e-96 323.2 0.0 1.2 1 0 0 1 1 1 1 Amidase CT_A_B PF02626.15 CCC68312.1 - 1.4e-82 277.3 0.0 2.1e-82 276.7 0.0 1.3 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 CCC68312.1 - 6.6e-63 212.0 0.1 1.3e-62 211.1 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 CCC68312.1 - 1.5e-44 152.1 0.0 3e-44 151.2 0.0 1.4 1 0 0 1 1 1 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 CCC68312.1 - 5.9e-40 136.3 0.0 1.1e-39 135.4 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CCC68312.1 - 1e-31 109.2 0.0 3.4e-31 107.6 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CCC68312.1 - 3.2e-15 55.7 0.7 2e-14 53.2 0.5 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CCC68312.1 - 3.2e-13 49.7 0.0 7.4e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CCC68312.1 - 1.7e-05 24.4 0.0 3.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.14 CCC68312.1 - 3.1e-05 24.1 0.0 5.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CCC68312.1 - 0.013 15.3 0.1 1.9 8.4 0.0 2.8 1 1 1 2 2 2 0 Biotin-lipoyl like RimK PF08443.11 CCC68312.1 - 0.043 13.4 0.0 0.14 11.7 0.0 1.9 1 1 0 1 1 1 0 RimK-like ATP-grasp domain ATPgrasp_Ter PF15632.6 CCC68312.1 - 0.11 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Glutaredoxin PF00462.24 CCC68313.1 - 9e-17 61.1 0.0 2.3e-16 59.7 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin Exo5 PF09810.9 CCC68314.1 - 1.1e-67 229.2 0.0 1.4e-67 228.8 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.7 CCC68314.1 - 0.00038 20.5 0.6 2.6 7.9 0.0 3.1 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily Cas_Cas4 PF01930.17 CCC68314.1 - 0.039 14.1 0.2 11 6.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF83 RAMP4 PF06624.12 CCC68315.1 - 4.9e-15 55.3 0.1 5.5e-15 55.2 0.1 1.0 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF2401 PF10287.9 CCC68316.1 - 5.2e-93 310.9 1.8 5.2e-93 310.9 1.8 2.8 3 0 0 3 3 3 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CCC68316.1 - 1.2e-28 99.4 0.2 5e-28 97.3 0.1 2.2 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) Macoilin PF09726.9 CCC68316.1 - 2 6.8 4.8 2.9 6.4 4.8 1.1 1 0 0 1 1 1 0 Macoilin family Gly_transf_sug PF04488.15 CCC68317.1 - 1.4e-23 83.4 0.1 3.4e-23 82.1 0.1 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Dimer_Tnp_hAT PF05699.14 CCC68318.1 - 0.00025 20.8 0.0 0.0011 18.7 0.0 2.1 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region Pkinase PF00069.25 CCC68319.1 - 8.4e-73 245.0 0.0 9.6e-73 244.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68319.1 - 1.2e-32 113.2 0.0 1.5e-32 112.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC68319.1 - 4.8e-05 22.8 0.0 9e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 CCC68319.1 - 0.00091 18.3 0.0 0.0061 15.5 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 CCC68319.1 - 0.0017 18.3 0.1 0.027 14.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CCC68319.1 - 0.024 14.0 0.5 0.074 12.4 0.2 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.25 CCC68320.1 - 8.6e-35 120.0 0.0 1.1e-34 119.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCC68320.1 - 4.3e-21 75.6 0.0 5.9e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCC68320.1 - 1.3e-07 31.7 0.0 2.4e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 CCC68320.1 - 0.0065 16.7 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Polysacc_synt_2 PF02719.15 CCC68320.1 - 0.022 13.9 0.1 0.036 13.2 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF3395 PF11875.8 CCC68320.1 - 0.037 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3395) NAD_binding_10 PF13460.6 CCC68320.1 - 0.067 13.1 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding LRR_4 PF12799.7 CCC68321.1 - 0.00068 20.0 12.6 0.2 12.1 3.4 4.1 1 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CCC68321.1 - 0.19 11.8 11.2 16 5.8 0.0 5.2 4 0 0 4 4 4 0 Leucine Rich repeat LRR_1 PF00560.33 CCC68321.1 - 3.4 8.6 6.6 34 5.5 0.6 4.9 5 1 0 5 5 5 0 Leucine Rich Repeat INCENP_ARK-bind PF03941.15 CCC68323.1 - 6.3e-16 58.1 1.0 1.6e-15 56.8 1.0 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region DUF1151 PF06625.11 CCC68323.1 - 0.3 11.0 15.0 0.038 13.9 10.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) TPR_1 PF00515.28 CCC68324.1 - 1.1e-11 44.0 8.3 4.8e-05 23.0 0.8 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCC68324.1 - 1.1e-09 37.7 3.9 0.015 15.4 0.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 CCC68324.1 - 8.2e-06 25.6 2.8 0.54 10.6 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCC68324.1 - 0.00027 21.2 0.4 0.4 11.0 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCC68324.1 - 0.00091 18.9 0.3 0.014 15.0 0.1 2.4 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.6 CCC68324.1 - 0.00098 19.6 0.2 0.12 12.9 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC68324.1 - 0.0014 18.8 3.2 0.0034 17.6 3.1 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CCC68324.1 - 0.01 16.2 2.1 0.03 14.7 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ThiS PF02597.20 CCC68324.1 - 0.092 13.4 0.6 4.3 8.0 0.0 2.6 2 0 0 2 2 2 0 ThiS family Ala_racemase_N PF01168.20 CCC68324.1 - 0.21 11.2 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Alanine racemase, N-terminal domain Glyco_transf_15 PF01793.16 CCC68325.1 - 2.9e-131 437.6 8.5 4e-131 437.1 8.5 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase cwf21 PF08312.12 CCC68326.1 - 7.9e-14 51.5 6.7 1.8e-13 50.4 6.7 1.6 1 0 0 1 1 1 1 cwf21 domain Trans_reg_C PF00486.28 CCC68326.1 - 0.11 12.6 1.5 2.6 8.2 0.2 2.3 1 1 1 2 2 2 0 Transcriptional regulatory protein, C terminal Alk_phosphatase PF00245.20 CCC68327.1 - 3e-119 398.7 0.0 3.6e-119 398.4 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 CCC68327.1 - 4.7e-05 22.9 0.0 8.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Peptidase_M10_C PF08548.11 CCC68327.1 - 0.019 14.8 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal Anp1 PF03452.14 CCC68328.1 - 4.8e-95 317.9 0.0 5.8e-95 317.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 CCC68328.1 - 0.045 13.6 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF2905 PF11146.8 CCC68329.1 - 0.031 14.4 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) Astro_capsid_p PF12226.8 CCC68329.1 - 0.24 10.5 7.8 0.38 9.9 7.8 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein FAM220 PF15487.6 CCC68329.1 - 1.4 8.4 12.8 0.016 14.8 5.1 1.5 2 0 0 2 2 2 0 FAM220 family LAT PF15234.6 CCC68329.1 - 2.5 7.8 11.2 0.12 12.1 5.7 1.5 2 0 0 2 2 2 0 Linker for activation of T-cells NOA36 PF06524.12 CCC68329.1 - 6.5 6.0 9.2 11 5.2 9.2 1.3 1 0 0 1 1 1 0 NOA36 protein Catalase PF00199.19 CCC68330.1 - 3.5e-182 605.7 0.4 4.5e-182 605.4 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CCC68330.1 - 1.1e-12 48.0 0.3 6.9e-12 45.4 0.1 2.4 2 0 0 2 2 2 1 Catalase-related immune-responsive CLTH PF10607.9 CCC68331.1 - 3.2e-13 49.8 1.9 3.2e-13 49.8 1.9 2.8 2 2 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 CCC68331.1 - 0.0002 21.3 0.5 0.0002 21.3 0.5 2.2 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 CCC68331.1 - 0.039 13.9 0.6 0.15 12.0 0.6 2.0 1 0 0 1 1 1 0 zinc-RING finger domain Exonuc_VII_L PF02601.15 CCC68331.1 - 0.076 12.6 1.4 0.097 12.2 1.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_2 PF13639.6 CCC68331.1 - 0.44 10.9 3.7 0.33 11.3 0.9 2.4 2 0 0 2 2 2 0 Ring finger domain zf-C2H2 PF00096.26 CCC68332.1 - 1.3e-07 31.7 5.3 0.00043 20.6 1.8 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC68332.1 - 6.9e-07 29.6 3.7 0.0085 16.9 1.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCC68332.1 - 0.05 13.9 2.2 0.82 10.0 0.8 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCC68332.1 - 0.072 13.1 3.1 1.3 9.1 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger TFIIS_C PF01096.18 CCC68332.1 - 0.074 12.9 0.6 0.56 10.1 0.0 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-C2H2_11 PF16622.5 CCC68332.1 - 0.09 12.6 2.9 3.3 7.5 0.3 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type C1_1 PF00130.22 CCC68332.1 - 0.15 11.9 0.7 20 5.1 0.2 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-H2C2_2 PF13465.6 CCC68332.1 - 0.17 12.3 4.8 1.2 9.7 1.3 2.8 2 1 0 2 2 2 0 Zinc-finger double domain RIG-I_C-RD PF11648.8 CCC68332.1 - 0.23 11.7 0.9 0.48 10.7 0.9 1.5 1 1 0 1 1 1 0 C-terminal domain of RIG-I NAC PF01849.18 CCC68333.1 - 8.3e-16 57.7 0.8 1.4e-15 57.0 0.1 1.8 2 0 0 2 2 2 1 NAC domain Fe-ADH PF00465.19 CCC68333.1 - 0.035 12.9 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 Iron-containing alcohol dehydrogenase BRICHOS PF04089.14 CCC68333.1 - 0.099 12.9 1.7 0.45 10.8 0.1 2.1 2 0 0 2 2 2 0 BRICHOS domain IclR PF01614.18 CCC68333.1 - 0.11 12.4 0.1 0.22 11.3 0.0 1.5 2 0 0 2 2 2 0 Bacterial transcriptional regulator Glyco_hydro_20b PF02838.15 CCC68333.1 - 0.23 12.2 2.4 0.24 12.2 0.2 1.9 1 1 1 2 2 2 0 Glycosyl hydrolase family 20, domain 2 Bac_rhodopsin PF01036.18 CCC68334.1 - 4.1e-58 196.6 18.5 4.8e-58 196.4 18.5 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.6 CCC68334.1 - 1.6 8.3 8.2 3 7.4 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ApbA PF02558.16 CCC68335.1 - 0.00022 20.9 0.0 0.00058 19.5 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CCC68335.1 - 0.048 13.8 0.0 0.19 12.0 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal EF1G PF00647.19 CCC68335.1 - 0.25 11.4 0.1 0.25 11.4 0.1 2.4 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain LMBR1 PF04791.16 CCC68335.1 - 2.1 7.2 11.6 3.6 6.4 11.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein YlqD PF11068.8 CCC68335.1 - 3.1 8.2 16.6 3.2 8.1 2.8 2.6 2 0 0 2 2 2 0 YlqD protein OmpH PF03938.14 CCC68335.1 - 4.7 7.5 24.8 9.7 6.5 10.8 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Uds1 PF15456.6 CCC68335.1 - 8.5 6.5 12.2 2.4 8.4 5.7 2.6 2 0 0 2 2 2 0 Up-regulated During Septation Fzo_mitofusin PF04799.13 CCC68335.1 - 9.1 5.8 13.8 0.82 9.2 6.4 2.3 2 0 0 2 2 2 0 fzo-like conserved region Lzipper-MIP1 PF14389.6 CCC68335.1 - 9.4 6.6 16.1 0.19 12.1 1.2 2.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 APS_kinase PF01583.20 CCC68336.1 - 3.7e-07 30.2 0.0 4.7e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.6 CCC68336.1 - 3.3e-06 27.7 0.1 1.7e-05 25.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 CCC68336.1 - 9.4e-05 21.8 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 CCC68336.1 - 0.00012 22.3 0.0 0.00015 21.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CCC68336.1 - 0.0011 19.5 0.0 0.0019 18.7 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 CCC68336.1 - 0.0017 18.8 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain SKI PF01202.22 CCC68336.1 - 0.0058 16.8 0.0 0.008 16.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate kinase dNK PF01712.19 CCC68336.1 - 0.0071 16.2 0.0 3.1 7.6 0.0 2.1 2 0 0 2 2 2 2 Deoxynucleoside kinase AAA_22 PF13401.6 CCC68336.1 - 0.015 15.5 0.0 0.025 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CCC68336.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 CCC68336.1 - 0.033 14.1 0.0 0.086 12.7 0.0 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 CCC68336.1 - 0.038 13.5 0.0 0.24 10.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 CCC68336.1 - 0.04 13.8 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_17 PF13207.6 CCC68336.1 - 0.054 13.9 0.0 0.14 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 CCC68336.1 - 0.077 12.0 0.1 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Torsin PF06309.11 CCC68336.1 - 0.079 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Torsin Rad17 PF03215.15 CCC68336.1 - 0.086 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 P-loop domain DUF815 PF05673.13 CCC68336.1 - 0.096 11.8 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.29 CCC68336.1 - 0.099 13.1 0.0 0.2 12.1 0.0 1.5 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CCC68336.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 CCC68336.1 - 0.14 11.9 0.0 0.78 9.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 CCC68336.1 - 0.17 10.8 0.0 0.3 10.0 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain Guanylate_kin PF00625.21 CCC68336.1 - 0.17 11.6 0.0 0.57 9.8 0.0 1.7 2 0 0 2 2 2 0 Guanylate kinase Pkinase PF00069.25 CCC68337.1 - 4.7e-41 140.9 8.1 3.8e-38 131.4 1.1 2.9 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68337.1 - 8.3e-22 77.7 0.1 1.6e-18 66.9 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCC68337.1 - 1.4e-06 27.8 0.0 2e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCC68337.1 - 0.0011 18.9 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CCC68337.1 - 0.074 12.4 0.3 0.12 11.8 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sybindin PF04099.12 CCC68338.1 - 6.8e-35 120.1 2.9 1.5e-14 54.1 0.4 3.1 3 0 0 3 3 3 3 Sybindin-like family Sedlin_N PF04628.13 CCC68338.1 - 1.2e-07 31.9 0.8 1.6e-07 31.5 0.3 1.4 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region Glyco_transf_34 PF05637.12 CCC68339.1 - 4.6e-73 245.9 1.4 5e-73 245.7 0.2 1.6 2 0 0 2 2 2 1 galactosyl transferase GMA12/MNN10 family TPR_1 PF00515.28 CCC68340.1 - 2.4e-18 65.1 7.9 2.4e-06 27.1 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCC68340.1 - 1.5e-16 59.1 10.1 0.00015 21.6 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 CCC68340.1 - 3.9e-14 52.9 0.9 0.002 18.6 0.0 4.4 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 CCC68340.1 - 5.4e-13 49.4 0.3 0.00013 22.5 0.1 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCC68340.1 - 5.7e-13 48.5 0.1 0.002 18.8 0.1 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCC68340.1 - 1.6e-12 46.9 8.6 4e-06 26.4 0.1 4.7 4 1 1 5 5 4 2 TPR repeat TPR_17 PF13431.6 CCC68340.1 - 9.8e-12 44.4 5.5 0.0011 19.2 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCC68340.1 - 8.3e-11 41.2 5.8 0.036 14.3 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 CCC68340.1 - 9.4e-10 38.5 0.2 0.0047 17.0 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 CCC68340.1 - 9.5e-08 32.3 0.1 0.0063 16.8 0.0 4.1 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCC68340.1 - 7.4e-06 26.3 0.3 9.1 7.2 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCC68340.1 - 2.1e-05 24.7 2.4 2 8.8 0.0 3.7 2 1 1 3 3 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCC68340.1 - 0.00028 20.7 0.1 9.2 6.6 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC68340.1 - 0.0029 17.8 3.0 0.085 13.1 0.0 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 CCC68340.1 - 0.0097 15.1 0.3 0.15 11.3 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 CCC68340.1 - 0.097 13.1 0.1 1.2 9.6 0.0 2.6 2 1 1 3 3 3 0 Bacterial transcriptional activator domain TPR_10 PF13374.6 CCC68340.1 - 0.099 12.5 4.7 6.4 6.8 0.2 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DEAD PF00270.29 CCC68341.1 - 2.7e-46 157.5 0.1 2.4e-44 151.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC68341.1 - 1.8e-32 112.0 0.1 2.1e-31 108.5 0.2 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC68341.1 - 2.8e-06 27.4 0.0 1.1e-05 25.5 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCC68341.1 - 0.0095 15.2 0.1 0.0095 15.2 0.1 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase Amidase PF01425.21 CCC68342.1 - 1.3e-90 304.6 0.0 1.7e-90 304.2 0.0 1.1 1 0 0 1 1 1 1 Amidase Ribosomal_L7Ae PF01248.26 CCC68343.1 - 3.5e-27 94.0 0.4 3.5e-27 94.0 0.4 1.4 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Adaptin_N PF01602.20 CCC68346.1 - 4.3e-113 378.7 10.7 6.3e-113 378.1 10.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 CCC68346.1 - 2.9e-52 176.3 1.0 8.4e-52 174.8 1.0 1.9 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 CCC68346.1 - 1.3e-51 173.9 0.6 4e-51 172.3 0.0 2.2 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Cnd1 PF12717.7 CCC68346.1 - 2.9e-06 27.4 0.1 2.9e-06 27.4 0.1 3.7 2 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 CCC68346.1 - 6.1e-06 26.4 0.0 1.8e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 CCC68346.1 - 9.5e-05 22.7 4.6 0.92 9.9 0.0 4.6 2 1 2 5 5 5 2 HEAT repeats Vac14_Fab1_bd PF12755.7 CCC68346.1 - 0.012 16.2 0.1 0.074 13.7 0.1 2.4 1 0 0 1 1 1 0 Vacuolar 14 Fab1-binding region HEAT PF02985.22 CCC68346.1 - 0.025 14.8 0.8 57 4.4 0.0 5.0 5 0 0 5 5 5 0 HEAT repeat Alpha_adaptinC2 PF02883.20 CCC68346.1 - 0.028 14.7 0.0 0.081 13.2 0.0 1.7 1 0 0 1 1 1 0 Adaptin C-terminal domain Ribosomal_L5_C PF00673.21 CCC68347.1 - 5.7e-27 93.7 0.0 2.5e-26 91.7 0.0 2.1 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 CCC68347.1 - 8.2e-14 51.7 0.0 2e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Flavokinase PF01687.17 CCC68348.1 - 5.5e-26 91.1 0.0 6.8e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Aconitase PF00330.20 CCC68350.1 - 2.3e-109 366.4 0.2 2.1e-108 363.3 0.2 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCC68350.1 - 5.4e-30 104.4 0.5 1.2e-29 103.3 0.0 1.9 2 0 0 2 2 2 1 Aconitase C-terminal domain Reticulon PF02453.17 CCC68351.1 - 3.5e-34 118.1 4.0 6e-34 117.3 4.0 1.4 1 0 0 1 1 1 1 Reticulon Aminotran_1_2 PF00155.21 CCC68352.1 - 7e-72 242.6 0.0 7e-72 242.6 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 CCC68352.1 - 5.2e-09 35.1 0.0 8.9e-09 34.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CCC68352.1 - 6.7e-05 22.0 0.0 0.00047 19.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 CCC68352.1 - 0.00053 19.4 1.0 0.18 11.1 0.1 2.4 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 CCC68352.1 - 0.00088 18.6 0.1 0.0023 17.3 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase DUF3767 PF12597.8 CCC68353.1 - 1.1e-35 121.4 0.1 1.7e-35 120.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) YrhK PF14145.6 CCC68353.1 - 0.13 12.2 0.6 0.22 11.4 0.6 1.3 1 0 0 1 1 1 0 YrhK-like protein Methyltransf_20 PF12147.8 CCC68353.1 - 0.14 11.3 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Putative methyltransferase PBECR1 PF18809.1 CCC68354.1 - 0.38 11.4 6.7 0.12 13.0 0.9 2.9 2 1 1 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 CFIA_Pcf11 PF11526.8 CCC68355.1 - 2.6e-30 104.7 11.0 2.6e-30 104.7 11.0 2.5 3 0 0 3 3 3 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.19 CCC68355.1 - 0.00091 19.1 1.1 0.02 14.7 0.0 3.1 3 0 0 3 3 3 1 VHS domain CTD_bind PF04818.13 CCC68355.1 - 0.032 15.0 0.0 0.13 13.1 0.0 2.1 1 0 0 1 1 1 0 RNA polymerase II-binding domain. zf-C2HE PF16278.5 CCC68355.1 - 0.043 14.3 0.8 0.29 11.6 0.1 2.7 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 CCC68355.1 - 0.079 13.4 1.6 15 6.2 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC68355.1 - 0.44 11.5 2.1 36 5.6 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf_UBZ PF18439.1 CCC68355.1 - 0.59 9.8 6.2 0.97 9.1 2.1 2.8 2 1 0 2 2 2 0 Ubiquitin-Binding Zinc Finger SIR4_SID PF16991.5 CCC68357.1 - 9.2e-59 198.1 3.2 9.2e-59 198.1 3.2 7.6 7 3 2 9 9 9 1 Sir4 SID domain COG2 PF06148.11 CCC68357.1 - 0.0032 17.5 6.3 0.01 15.9 6.3 1.9 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 ADK PF00406.22 CCC68358.1 - 3.2e-61 205.9 0.0 3.8e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CCC68358.1 - 1.9e-23 83.4 0.0 3.1e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CCC68358.1 - 8.9e-18 64.0 0.0 2.1e-17 62.8 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CCC68358.1 - 1.9e-08 34.6 0.0 3.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCC68358.1 - 9.3e-06 26.2 0.0 2.2e-05 25.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 CCC68358.1 - 0.044 13.5 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Thymidylate_kin PF02223.17 CCC68358.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase Histone_H2A_C PF16211.5 CCC68359.1 - 5.5e-21 74.0 1.3 8.9e-21 73.3 1.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 CCC68359.1 - 1.2e-17 64.5 0.0 1.7e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCC68359.1 - 7.4e-06 26.2 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone LcrG PF07216.12 CCC68359.1 - 0.053 13.5 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 LcrG protein Histone PF00125.24 CCC68360.1 - 2.4e-19 70.0 1.8 3.2e-19 69.6 1.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCC68360.1 - 7.1e-06 26.2 0.1 1.5e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 CCC68360.1 - 0.0015 19.0 0.0 0.0026 18.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-W PF15510.6 CCC68360.1 - 0.018 15.2 0.0 0.027 14.7 0.0 1.2 1 0 0 1 1 1 0 CENP-W protein YscO-like PF16789.5 CCC68360.1 - 0.069 13.2 0.1 0.08 13.0 0.1 1.1 1 0 0 1 1 1 0 YscO-like protein VIT1 PF01988.19 CCC68361.1 - 5.6e-60 202.9 0.1 5.6e-60 202.9 0.1 1.3 2 0 0 2 2 2 1 VIT family CRF1 PF10380.9 CCC68362.1 - 4.9e-16 59.1 2.5 1.4e-15 57.6 2.5 1.7 1 0 0 1 1 1 1 Transcription factor CRF1 Svf1_C PF17187.4 CCC68363.1 - 1.2e-43 148.8 0.1 1.9e-43 148.1 0.1 1.4 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain Svf1 PF08622.10 CCC68363.1 - 2.9e-37 128.2 1.2 7.3e-37 126.9 0.3 1.9 2 0 0 2 2 2 1 Svf1-like N-terminal lipocalin domain PRKCSH-like PF12999.7 CCC68364.1 - 3.9e-36 124.5 10.5 3.9e-36 124.5 10.5 2.7 2 1 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 CCC68364.1 - 3.7e-16 59.2 3.9 1.7e-15 57.0 2.5 2.8 1 1 1 2 2 2 1 Glucosidase II beta subunit-like protein Nucleolin_bd PF16725.5 CCC68364.1 - 0.38 10.4 2.6 3.2 7.5 0.7 3.0 2 0 0 2 2 2 0 Nucleolin binding domain Spc24 PF08286.11 CCC68364.1 - 0.96 9.7 13.0 0.041 14.1 2.7 3.1 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 TPR_MLP1_2 PF07926.12 CCC68364.1 - 1.1 9.3 19.3 1.9 8.5 6.6 3.0 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 CCC68364.1 - 3.9 7.0 13.9 0.57 9.7 4.7 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit F-box-like PF12937.7 CCC68365.1 - 0.0017 18.2 0.4 0.0046 16.8 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CCC68365.1 - 0.013 15.4 1.1 0.038 13.9 0.1 2.1 2 0 0 2 2 2 0 F-box domain F-box_4 PF15966.5 CCC68365.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.7 2 0 0 2 2 2 0 F-box MPDZ_u10 PF16667.5 CCC68365.1 - 0.71 10.8 3.4 0.6 11.1 0.9 2.2 2 0 0 2 2 2 0 Unstructured region 10 on multiple PDZ protein Septin PF00735.18 CCC68366.1 - 2.8e-65 220.4 4.2 3.7e-65 220.0 4.2 1.1 1 0 0 1 1 1 1 Septin Pox_A32 PF04665.12 CCC68366.1 - 0.00025 20.6 0.0 0.00055 19.5 0.0 1.6 1 0 0 1 1 1 1 Poxvirus A32 protein Roc PF08477.13 CCC68366.1 - 0.00026 21.2 0.1 0.00062 20.0 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CCC68366.1 - 0.00069 19.6 0.3 0.0071 16.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 CCC68366.1 - 0.0017 18.9 0.4 0.0045 17.5 0.1 1.9 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.23 CCC68366.1 - 0.0027 17.8 0.1 0.0062 16.6 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 CCC68366.1 - 0.0054 16.3 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 CCC68366.1 - 0.009 16.3 0.0 0.035 14.4 0.0 1.8 1 1 0 2 2 2 1 AAA domain G-alpha PF00503.20 CCC68366.1 - 0.0093 15.2 4.8 0.015 14.5 4.9 1.7 1 1 0 1 1 1 1 G-protein alpha subunit RNA_helicase PF00910.22 CCC68366.1 - 0.015 15.7 0.0 0.046 14.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 CCC68366.1 - 0.017 15.1 0.0 0.033 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Bac_DnaA PF00308.18 CCC68366.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein T2SSE PF00437.20 CCC68366.1 - 0.019 14.1 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 CCC68366.1 - 0.023 14.4 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 CCC68366.1 - 0.026 14.1 0.1 0.052 13.2 0.1 1.5 1 0 0 1 1 1 0 Ras family AAA_16 PF13191.6 CCC68366.1 - 0.038 14.4 0.0 0.083 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 CCC68366.1 - 0.05 13.3 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 CCC68366.1 - 0.053 13.5 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CCC68366.1 - 0.065 13.4 0.0 0.22 11.6 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 CCC68366.1 - 0.079 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 CCC68366.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.14 CCC68366.1 - 0.089 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad9_Rad53_bind PF08605.10 CCC68367.1 - 2.9e-42 143.9 0.0 6.5e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.26 CCC68367.1 - 7.9e-12 45.4 1.2 5e-11 42.8 0.2 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCC68367.1 - 3.6e-05 24.1 0.9 0.0081 16.6 0.1 4.1 3 1 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 CCC68367.1 - 0.0015 18.4 0.1 0.0084 16.0 0.1 2.2 2 0 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain zf-C2H2 PF00096.26 CCC68368.1 - 7.6e-11 41.8 6.9 9.4e-05 22.7 0.8 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC68368.1 - 8.2e-08 32.3 8.7 8.1e-07 29.2 2.5 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC68368.1 - 1.5e-07 31.6 6.6 0.0056 17.4 0.6 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCC68368.1 - 0.00011 22.5 1.2 0.26 11.8 0.2 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-MYST PF17772.1 CCC68368.1 - 0.61 9.7 3.6 1.6 8.4 0.0 3.0 3 0 0 3 3 3 0 MYST family zinc finger domain zf-C2H2_6 PF13912.6 CCC68368.1 - 1.3 9.1 4.5 0.35 10.9 0.3 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CCC68368.1 - 1.7 9.3 6.8 1.3 9.7 2.0 3.2 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf_C2H2_ZHX PF18387.1 CCC68368.1 - 5.4 6.7 12.0 0.96 9.1 0.2 3.3 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Aha1_N PF09229.11 CCC68369.1 - 3.6e-36 124.4 0.6 6.2e-36 123.6 0.2 1.7 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 CCC68369.1 - 8.6e-11 42.2 0.1 1.6e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Fungal_trans_2 PF11951.8 CCC68370.1 - 3.1e-13 49.3 0.1 3.1e-13 49.3 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC68370.1 - 9.6e-10 38.4 10.8 1.5e-09 37.8 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cpn60_TCP1 PF00118.24 CCC68371.1 - 5.4e-154 513.5 13.6 6.1e-154 513.3 13.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Glyco_transf_8 PF01501.20 CCC68371.1 - 0.046 13.3 0.0 0.082 12.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 8 MRP-S31 PF15433.6 CCC68371.1 - 0.19 11.4 0.1 0.33 10.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 Ras PF00071.22 CCC68372.1 - 3.6e-50 169.7 0.0 4.1e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC68372.1 - 4.7e-18 65.5 0.0 6.6e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC68372.1 - 1.6e-05 24.4 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Dimer_Tnp_hAT PF05699.14 CCC68373.1 - 7.1e-09 35.3 0.1 2.8e-08 33.4 0.1 2.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region W2 PF02020.18 CCC68374.1 - 2.5e-15 56.4 4.1 2.5e-15 56.4 4.1 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 CCC68374.1 - 3.1e-12 45.7 16.2 0.00054 19.6 2.7 4.2 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 CCC68374.1 - 3.1e-10 40.0 0.0 6.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase DUF4954 PF16314.5 CCC68374.1 - 1.5e-07 30.0 4.0 2.7e-06 25.8 0.2 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4954) NTP_transf_3 PF12804.7 CCC68374.1 - 0.0039 17.5 0.0 0.0076 16.6 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Nudix_N PF12535.8 CCC68374.1 - 0.06 13.0 0.0 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Hexapep_2 PF14602.6 CCC68374.1 - 0.061 13.1 17.2 0.93 9.3 3.7 3.8 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CCC68374.1 - 0.091 11.7 2.9 0.33 9.9 2.9 1.8 1 1 0 1 1 1 0 L-fucokinase CYSTM PF12734.7 CCC68375.1 - 8.9e-07 29.1 72.5 0.00034 20.9 43.4 4.8 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance Pro-rich PF15240.6 CCC68375.1 - 0.013 15.7 21.8 0.016 15.5 21.8 1.1 1 0 0 1 1 1 0 Proline-rich Pex14_N PF04695.13 CCC68375.1 - 0.25 12.0 9.0 0.27 11.9 9.0 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PIP5K PF01504.18 CCC68376.1 - 2.4e-94 315.6 4.9 2.4e-94 315.6 4.9 2.8 3 0 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase Zn_clus PF00172.18 CCC68377.1 - 2.2e-09 37.3 7.4 3.9e-09 36.5 7.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4337 PF14235.6 CCC68377.1 - 0.27 11.3 2.5 1.1 9.3 2.5 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) EMC3_TMCO1 PF01956.16 CCC68377.1 - 3.7 7.3 7.0 8.9 6.0 7.0 1.6 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like EST1_DNA_bind PF10373.9 CCC68378.1 - 5.9e-47 160.5 7.8 1.6e-46 159.1 7.8 1.7 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CCC68378.1 - 9.7e-21 74.8 0.7 9.7e-21 74.8 0.7 3.4 3 1 0 3 3 3 1 Telomerase activating protein Est1 Cation_efflux PF01545.21 CCC68379.1 - 1.4e-41 142.5 14.3 1.4e-41 142.5 14.3 2.6 2 1 0 2 2 2 1 Cation efflux family Plasmod_dom_1 PF09715.10 CCC68379.1 - 0.19 11.8 3.5 0.34 11.0 0.7 2.9 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Renin_r PF07850.14 CCC68379.1 - 0.32 11.6 2.8 12 6.6 0.0 3.3 2 0 0 2 2 2 0 Renin receptor-like protein DUF5383 PF17355.2 CCC68379.1 - 4 7.8 5.0 1 9.7 0.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5383) DUF872 PF05915.12 CCC68379.1 - 8 6.7 7.8 1.8 8.8 0.6 3.2 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) Coq4 PF05019.13 CCC68380.1 - 5.9e-91 303.7 0.0 7.5e-91 303.4 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 DASH_Spc19 PF08287.11 CCC68381.1 - 2.5e-36 124.9 14.4 2.9e-36 124.7 14.4 1.0 1 0 0 1 1 1 1 Spc19 TolA_bind_tri PF16331.5 CCC68381.1 - 0.0012 18.9 9.2 0.3 11.2 0.2 3.0 3 0 0 3 3 3 2 TolA binding protein trimerisation GIT_CC PF16559.5 CCC68381.1 - 0.012 15.5 9.4 1.3 8.9 0.6 3.4 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor TBCA PF02970.16 CCC68381.1 - 0.033 14.5 10.5 0.56 10.6 3.8 2.8 2 1 1 3 3 3 0 Tubulin binding cofactor A HEPN_Cthe2314 PF18730.1 CCC68381.1 - 0.038 14.0 0.4 0.066 13.3 0.4 1.4 1 0 0 1 1 1 0 Cthe_2314-like HEPN RNA_pol_Rpb5_C PF01191.19 CCC68381.1 - 0.076 12.9 1.9 0.084 12.7 0.1 1.9 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain DASH_Duo1 PF08651.10 CCC68381.1 - 0.12 12.2 7.5 0.84 9.5 0.5 2.8 3 0 0 3 3 3 0 DASH complex subunit Duo1 HAUS5 PF14817.6 CCC68381.1 - 0.16 10.7 10.0 0.64 8.7 6.3 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 5 Syntaxin-6_N PF09177.11 CCC68381.1 - 0.46 11.1 11.7 6.9 7.3 0.1 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Fib_alpha PF08702.10 CCC68381.1 - 0.57 10.4 10.2 4.5 7.5 4.7 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FapA PF03961.13 CCC68381.1 - 2.4 6.7 8.0 1.2 7.7 5.6 1.5 1 1 0 2 2 2 0 Flagellar Assembly Protein A Occludin_ELL PF07303.13 CCC68381.1 - 2.4 8.9 8.2 2.2 9.1 0.1 2.7 1 1 1 2 2 2 0 Occludin homology domain SlyX PF04102.12 CCC68381.1 - 5.7 7.6 8.8 6.5 7.4 0.6 3.3 3 1 0 3 3 3 0 SlyX Sas6_CC PF18594.1 CCC68381.1 - 8.3 6.3 10.8 5.7 6.8 4.1 2.7 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain FHA PF00498.26 CCC68382.1 - 1.9e-17 63.3 0.2 2.2e-16 59.9 0.4 2.4 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 CCC68382.1 - 9.3e-06 25.9 0.8 3.2e-05 24.2 0.0 2.2 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain DUF3053 PF11254.8 CCC68382.1 - 0.26 10.8 4.4 0.92 9.0 4.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3053) DUF4407 PF14362.6 CCC68382.1 - 1.3 8.3 6.1 2.1 7.6 6.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran_CTD PF16326.5 CCC68382.1 - 1.4 9.2 12.3 0.87 9.9 9.8 2.0 1 1 0 1 1 1 0 ABC transporter C-terminal domain SET PF00856.28 CCC68383.1 - 8.9e-05 22.9 0.0 0.00017 22.0 0.0 1.6 1 1 0 1 1 1 1 SET domain ApbA_C PF08546.11 CCC68384.1 - 2.5e-13 50.3 0.0 5.9e-13 49.1 0.0 1.6 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal CoaE PF01121.20 CCC68385.1 - 9e-63 211.2 0.0 1.1e-62 210.9 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 CCC68385.1 - 0.00022 21.8 0.0 0.0014 19.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCC68385.1 - 0.00041 20.5 0.0 0.0016 18.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 CCC68385.1 - 0.01 16.1 0.0 0.021 15.1 0.0 1.5 2 0 0 2 2 2 0 AAA domain dNK PF01712.19 CCC68385.1 - 0.014 15.2 0.2 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase AAA_17 PF13207.6 CCC68385.1 - 0.016 15.6 0.1 0.16 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 CCC68385.1 - 0.018 15.2 0.0 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase PRK PF00485.18 CCC68385.1 - 0.054 13.2 0.1 0.14 11.9 0.0 1.8 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Cytidylate_kin2 PF13189.6 CCC68385.1 - 0.061 13.4 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 Cytidylate kinase-like family UPF0688 PF15772.5 CCC68386.1 - 6 7.0 27.0 1.8 8.8 24.1 1.6 2 0 0 2 2 2 0 UPF0688 family DEAD PF00270.29 CCC68387.1 - 3.1e-40 137.8 0.2 1.9e-39 135.3 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC68387.1 - 4.9e-23 81.6 0.1 2.5e-22 79.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC68387.1 - 3.4e-06 27.2 0.4 1e-05 25.6 0.3 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCC68387.1 - 0.00085 18.6 0.0 0.0014 17.9 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Nod1 PF17114.5 CCC68387.1 - 0.15 12.2 3.3 0.093 12.9 0.5 2.0 3 0 0 3 3 3 0 Gef2-related medial cortical node protein Nod1 zf-CCCH_4 PF18044.1 CCC68388.1 - 6e-09 35.5 3.3 1.2e-08 34.6 3.3 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 CCC68388.1 - 1e-07 31.7 3.6 1.7e-07 31.0 3.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCC68388.1 - 3e-07 30.3 7.4 5.8e-07 29.4 7.4 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 CCC68388.1 - 0.0014 19.3 0.8 0.0034 18.1 0.8 1.6 1 0 0 1 1 1 1 Torus domain Nucleoporin_FG PF13634.6 CCC68388.1 - 0.0015 19.4 151.5 0.015 16.2 21.6 6.0 1 1 4 5 5 5 3 Nucleoporin FG repeat region zf-CCCH_2 PF14608.6 CCC68388.1 - 0.21 12.1 5.9 0.4 11.2 5.9 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger SIR2 PF02146.17 CCC68389.1 - 9e-30 103.9 0.0 1.3e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Sir2 family BLOC1_2 PF10046.9 CCC68389.1 - 0.042 14.1 0.3 0.12 12.6 0.3 1.8 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spt5_N PF11942.8 CCC68390.1 - 0.69 10.9 15.4 2.6 9.1 9.6 2.8 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal HALZ PF02183.18 CCC68391.1 - 0.052 13.8 1.2 0.052 13.8 1.2 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper YabA PF06156.13 CCC68391.1 - 0.12 13.0 0.2 0.12 13.0 0.2 2.6 3 0 0 3 3 3 0 Initiation control protein YabA Phosducin PF02114.16 CCC68392.1 - 2.1e-07 30.2 0.1 2.2e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 CCC68392.1 - 4.8e-05 23.3 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AHSP PF09236.10 CCC68392.1 - 0.038 14.4 0.7 0.2 12.1 0.2 2.3 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein YobH PF13996.6 CCC68392.1 - 0.18 11.9 0.0 3.6 7.7 0.0 2.2 2 0 0 2 2 2 0 YobH-like protein PPV_E1_N PF00524.18 CCC68392.1 - 1.8 9.0 7.1 2.8 8.4 4.9 2.0 1 1 1 2 2 2 0 E1 Protein, N terminal domain Metallophos PF00149.28 CCC68393.1 - 5.8e-11 43.3 1.9 9.5e-11 42.6 1.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Orf78 PF06024.12 CCC68393.1 - 0.011 16.1 0.1 3.3 8.1 0.1 2.4 2 0 0 2 2 2 0 Orf78 (ac78) SAS4 PF15460.6 CCC68394.1 - 3.2e-31 107.3 2.1 3.2e-31 107.3 2.1 2.9 3 0 0 3 3 3 1 Something about silencing, SAS, complex subunit 4 Prok-TraM PF09228.10 CCC68394.1 - 0.075 13.4 0.2 0.54 10.7 0.0 2.5 2 1 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Nipped-B_C PF12830.7 CCC68395.1 - 9.4e-33 113.7 1.5 1.8e-31 109.6 1.0 2.9 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 CCC68395.1 - 1.9e-12 47.2 1.3 7.4e-12 45.3 0.3 2.7 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.7 CCC68395.1 - 0.24 11.4 16.7 0.4 10.7 0.3 5.1 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 PXA PF02194.15 CCC68396.1 - 4.9e-18 65.7 5.9 8.7e-18 64.9 0.6 2.9 2 1 0 2 2 2 1 PXA domain CybS PF05328.12 CCC68398.1 - 5.1e-46 155.7 0.0 6.4e-46 155.3 0.0 1.1 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit UQ_con PF00179.26 CCC68399.1 - 3.2e-44 150.0 0.0 4.2e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.10 CCC68399.1 - 1.5e-27 95.2 1.1 2.6e-27 94.4 1.1 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain Calsarcin PF05556.11 CCC68399.1 - 0.009 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-binding protein (Calsarcin) Ada3 PF10198.9 CCC68400.1 - 1.3e-44 151.5 3.5 1.3e-44 151.5 3.5 2.5 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 MRP-S28 PF10213.9 CCC68402.1 - 3.3e-47 160.1 6.5 7.4e-47 158.9 4.3 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein HMG_box PF00505.19 CCC68403.1 - 1.1e-10 41.8 3.2 1.1e-10 41.8 3.2 2.2 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCC68403.1 - 4.3e-08 33.6 1.8 4.3e-08 33.6 1.8 2.1 2 0 0 2 2 2 1 HMG-box domain TAF4 PF05236.14 CCC68403.1 - 0.00063 19.6 0.9 0.0013 18.6 0.9 1.5 1 1 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family DUF3086 PF11285.8 CCC68403.1 - 0.037 13.1 0.1 0.037 13.1 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3086) Transketolase_N PF00456.21 CCC68403.1 - 0.06 12.3 0.7 0.1 11.5 0.7 1.3 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain IPK PF03770.16 CCC68404.1 - 4e-55 186.7 2.0 5.2e-55 186.4 1.4 1.5 2 0 0 2 2 2 1 Inositol polyphosphate kinase GTP_EFTU PF00009.27 CCC68405.1 - 1.5e-44 151.9 0.0 4.7e-44 150.3 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCC68405.1 - 3.8e-35 120.6 1.4 3.8e-35 120.6 1.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCC68405.1 - 4.1e-09 36.7 1.2 1.4e-08 35.0 1.2 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCC68405.1 - 0.002 18.2 0.1 0.016 15.3 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase TFIIA PF03153.13 CCC68405.1 - 0.036 14.1 39.3 0.052 13.6 39.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_U32_C PF16325.5 CCC68405.1 - 0.093 13.0 0.1 0.36 11.1 0.1 2.0 1 0 0 1 1 1 0 Peptidase family U32 C-terminal domain HSP20 PF00011.21 CCC68406.1 - 1.6e-08 34.6 0.0 1.6e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Hsp20/alpha crystallin family Sec7 PF01369.20 CCC68407.1 - 6.8e-72 241.0 0.1 2.4e-71 239.2 0.1 2.1 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 CCC68407.1 - 1.5e-42 145.2 0.3 1.5e-42 145.2 0.3 3.5 4 0 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 CCC68407.1 - 1.1e-28 98.9 11.4 2.7e-28 97.6 0.2 5.7 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) DCB PF16213.5 CCC68407.1 - 5.4e-17 62.0 7.3 1.4e-16 60.7 1.2 3.7 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 IFN-gamma PF00714.17 CCC68407.1 - 1.1 9.1 5.8 0.78 9.6 2.2 2.7 3 0 0 3 3 3 0 Interferon gamma AMP-binding PF00501.28 CCC68408.1 - 4.9e-83 279.1 0.0 6.1e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCC68408.1 - 8.1e-23 81.2 0.0 1.9e-22 80.0 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 CCC68408.1 - 2e-20 72.4 0.4 4.3e-20 71.4 0.4 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Mem_trans PF03547.18 CCC68409.1 - 1.5e-29 102.6 1.4 5.4e-18 64.6 0.4 2.2 2 0 0 2 2 2 2 Membrane transport protein Stm1_N PF09598.10 CCC68410.1 - 6e-08 33.4 6.9 6e-08 33.4 6.9 4.5 2 2 1 3 3 3 1 Stm1 HABP4_PAI-RBP1 PF04774.15 CCC68410.1 - 0.012 16.4 12.6 0.012 16.4 12.6 2.9 3 1 0 3 3 3 0 Hyaluronan / mRNA binding family NAM-associated PF14303.6 CCC68410.1 - 7 7.3 15.4 14 6.3 15.4 1.4 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RCR PF12273.8 CCC68411.1 - 7.1e-10 39.6 0.0 1e-09 39.1 0.0 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Peptidase_C42 PF05533.12 CCC68411.1 - 0.09 12.8 0.1 3.7 7.7 0.0 2.2 1 1 1 2 2 2 0 Beet yellows virus-type papain-like endopeptidase C42 CpxA_peri PF16527.5 CCC68412.1 - 0.025 15.0 0.0 0.04 14.3 0.0 1.3 1 0 0 1 1 1 0 Two-component sensor protein CpxA, periplasmic domain MAP17 PF15807.5 CCC68412.1 - 0.12 12.7 0.4 0.12 12.7 0.4 1.6 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Stb3 PF10330.9 CCC68413.1 - 2.3e-31 107.7 0.0 5.4e-31 106.5 0.0 1.6 1 0 0 1 1 1 1 Putative Sin3 binding protein TAFII55_N PF04658.13 CCC68413.1 - 6.8 6.4 15.3 0.3 10.8 1.8 2.9 2 1 1 3 3 3 0 TAFII55 protein conserved region RSB_motif PF16294.5 CCC68413.1 - 9.8 6.5 16.6 16 5.9 0.0 3.5 3 0 0 3 3 3 0 RNSP1-SAP18 binding (RSB) motif CDC37_N PF03234.14 CCC68414.1 - 1.2e-43 149.1 9.6 1.2e-43 149.1 9.6 3.4 3 1 0 3 3 3 1 Cdc37 N terminal kinase binding CDC37_M PF08565.11 CCC68414.1 - 9.2e-41 138.5 4.9 9.2e-41 138.5 4.9 2.9 4 0 0 4 4 4 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.10 CCC68414.1 - 5.2e-29 100.3 4.8 5.2e-29 100.3 4.8 2.9 3 0 0 3 3 3 1 Cdc37 C terminal domain hnRNP_Q_AcD PF18360.1 CCC68414.1 - 0.047 13.6 2.1 0.37 10.8 0.0 3.2 4 0 0 4 4 4 0 Heterogeneous nuclear ribonucleoprotein Q acidic domain BST2 PF16716.5 CCC68414.1 - 7.1 7.3 7.4 8 7.1 0.9 3.2 3 0 0 3 3 3 0 Bone marrow stromal antigen 2 TFIID_30kDa PF03540.13 CCC68415.1 - 1.3e-24 85.9 0.1 2.8e-24 84.8 0.1 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Sec5 PF15469.6 CCC68416.1 - 2e-53 181.1 11.0 2e-53 181.1 11.0 3.5 4 0 0 4 4 4 1 Exocyst complex component Sec5 Vps51 PF08700.11 CCC68416.1 - 0.005 16.9 2.1 0.005 16.9 2.1 2.9 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.11 CCC68416.1 - 0.0086 16.2 2.1 0.029 14.5 2.1 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Occludin_ELL PF07303.13 CCC68416.1 - 0.25 12.1 3.3 0.57 10.9 1.1 2.8 2 1 1 3 3 3 0 Occludin homology domain WD40 PF00400.32 CCC68417.1 - 0.27 12.2 3.8 10 7.2 1.5 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat Sec1 PF00995.23 CCC68418.1 - 1.4e-82 278.8 0.1 1.8e-82 278.4 0.1 1.1 1 0 0 1 1 1 1 Sec1 family Cwf_Cwc_15 PF04889.12 CCC68419.1 - 5.6e-19 68.8 41.2 7.6e-09 35.7 33.9 2.9 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein PMSI1 PF15322.6 CCC68419.1 - 0.29 10.5 7.1 0.62 9.5 7.1 1.5 1 1 0 1 1 1 0 Protein missing in infertile sperm 1, putative TMEM247 PF15444.6 CCC68419.1 - 0.42 10.6 6.2 0.51 10.3 6.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 PAC1 PF16094.5 CCC68419.1 - 1 8.5 5.1 1.2 8.2 5.1 1.2 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 NOA36 PF06524.12 CCC68419.1 - 2 7.7 10.7 3.3 7.0 10.7 1.4 1 0 0 1 1 1 0 NOA36 protein PA26 PF04636.13 CCC68419.1 - 3.9 6.3 9.3 4.6 6.0 9.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FAM60A PF15396.6 CCC68419.1 - 6 6.8 14.6 25 4.8 14.6 1.8 1 1 0 1 1 1 0 Protein Family FAM60A AAA_11 PF13086.6 CCC68419.1 - 6.7 6.4 14.3 2.1 8.1 11.6 1.5 1 1 1 2 2 2 0 AAA domain CDC45 PF02724.14 CCC68419.1 - 8.6 4.5 18.3 10 4.2 18.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SH3_1 PF00018.28 CCC68420.1 - 3.8e-13 48.8 1.4 2.9e-12 46.0 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CCC68420.1 - 9.8e-10 38.2 0.4 2.9e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CCC68420.1 - 1.1e-05 25.0 0.0 2.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TPR_19 PF14559.6 CCC68421.1 - 2.5e-05 24.7 0.7 0.65 10.6 0.1 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC68421.1 - 5.7e-05 23.3 0.9 0.12 12.6 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 CCC68421.1 - 8.9e-05 22.3 0.0 2.2 8.6 0.0 4.1 5 0 0 5 5 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCC68421.1 - 0.00014 21.8 0.1 1.8 8.9 0.0 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCC68421.1 - 0.0082 15.8 2.4 6.3 6.6 0.0 4.0 4 0 0 4 4 4 1 TPR repeat TPR_14 PF13428.6 CCC68421.1 - 0.0098 16.6 0.0 29 5.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat SpoVIF PF14069.6 CCC68421.1 - 0.015 15.1 0.1 0.041 13.7 0.1 1.7 1 0 0 1 1 1 0 Stage VI sporulation protein F TPR_1 PF00515.28 CCC68421.1 - 0.025 14.4 0.0 12 5.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.6 CCC68421.1 - 0.056 12.7 0.1 0.19 10.9 0.0 2.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCC68421.1 - 0.073 13.4 0.4 14 6.0 0.0 3.7 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2989 PF11207.8 CCC68421.1 - 0.084 12.6 0.3 3.9 7.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) TPR_7 PF13176.6 CCC68421.1 - 0.085 12.9 0.0 15 5.9 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat YfdX PF10938.8 CCC68421.1 - 0.11 12.5 0.9 0.53 10.2 1.0 2.2 1 1 0 1 1 1 0 YfdX protein AA_permease PF00324.21 CCC68422.1 - 9.8e-73 245.4 48.5 7.4e-72 242.5 48.5 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC68422.1 - 1.7e-30 106.2 47.7 1.1e-29 103.6 47.7 1.9 1 1 0 1 1 1 1 Amino acid permease DUF2618 PF10940.8 CCC68422.1 - 0.12 12.2 1.3 1.1 9.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2618) SAC3_GANP PF03399.16 CCC68423.1 - 1.9e-103 345.9 2.9 5e-102 341.2 0.3 2.7 2 0 0 2 2 2 2 SAC3/GANP family SAC3 PF12209.8 CCC68423.1 - 6.5e-21 74.3 0.9 6.5e-21 74.3 0.9 3.0 2 0 0 2 2 2 1 Leucine permease transcriptional regulator helical domain DicB PF05358.11 CCC68423.1 - 0.0063 16.6 2.1 0.2 11.8 0.1 2.8 2 0 0 2 2 2 1 DicB protein CSN8_PSD8_EIF3K PF10075.9 CCC68423.1 - 0.022 14.7 0.3 0.31 11.0 0.0 3.0 3 0 0 3 3 3 0 CSN8/PSMD8/EIF3K family Semialdhyde_dhC PF02774.18 CCC68424.1 - 1.5e-44 152.3 0.0 2.3e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 CCC68424.1 - 1.2e-30 106.5 0.0 2e-30 105.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 CCC68424.1 - 0.031 14.5 0.0 0.079 13.2 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DXP_reductoisom PF02670.16 CCC68424.1 - 0.072 13.8 0.0 0.19 12.5 0.0 1.8 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase RNA_polI_A14 PF08203.11 CCC68425.1 - 2.6e-27 95.4 1.6 3.2e-27 95.0 0.1 1.8 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 IL13 PF03487.13 CCC68425.1 - 0.11 12.3 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Interleukin-13 Pro_isomerase PF00160.21 CCC68426.1 - 1.7e-47 161.6 0.0 1.9e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.6 CCC68426.1 - 0.018 15.1 0.1 0.076 13.1 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin domain RCR PF12273.8 CCC68427.1 - 0.0021 18.7 4.7 0.0063 17.2 4.7 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Hph PF13694.6 CCC68427.1 - 0.0036 17.6 0.3 0.0056 17.0 0.3 1.3 1 0 0 1 1 1 1 Sec63/Sec62 complex-interacting family F-box-like PF12937.7 CCC68428.1 - 1.2e-05 25.0 0.0 3e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CCC68428.1 - 0.0011 18.7 0.0 0.0033 17.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 CCC68428.1 - 0.0016 18.3 0.0 0.0069 16.3 0.0 2.1 2 0 0 2 2 2 1 F-box DUF3760 PF12586.8 CCC68428.1 - 0.078 13.2 0.3 0.22 11.7 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) BTB_2 PF02214.22 CCC68429.1 - 1.5e-07 31.6 0.6 0.0024 18.2 0.2 3.3 2 2 0 2 2 2 2 BTB/POZ domain Flocculin_t3 PF13928.6 CCC68430.1 - 2.6e-11 43.9 17.1 2.6e-11 43.9 17.1 4.3 1 1 2 3 3 3 1 Flocculin type 3 repeat Rad4 PF03835.15 CCC68430.1 - 0.021 14.5 0.2 0.03 14.0 0.2 1.3 1 0 0 1 1 1 0 Rad4 transglutaminase-like domain ABC_membrane PF00664.23 CCC68431.1 - 8.4e-89 297.8 37.7 2.7e-46 158.4 19.3 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCC68431.1 - 3.3e-50 170.1 0.3 5.4e-31 107.9 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 CCC68431.1 - 4e-09 36.2 8.1 0.0019 17.7 1.3 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 CCC68431.1 - 1.1e-05 25.5 0.3 0.082 13.0 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 CCC68431.1 - 3.6e-05 23.4 0.7 0.18 11.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 CCC68431.1 - 0.00015 21.6 0.1 0.27 10.9 0.0 2.8 3 1 0 3 3 2 2 AAA ATPase domain AAA_23 PF13476.6 CCC68431.1 - 0.00049 20.7 2.4 0.13 12.7 0.1 2.9 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 CCC68431.1 - 0.00068 19.6 0.1 0.67 9.8 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CCC68431.1 - 0.0024 18.3 0.0 2 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CCC68431.1 - 0.0054 16.3 0.2 1.4 8.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF87 PF01935.17 CCC68431.1 - 0.0059 16.7 2.8 0.38 10.8 0.2 3.1 2 0 0 2 2 2 1 Helicase HerA, central domain AIG1 PF04548.16 CCC68431.1 - 0.013 14.8 2.1 0.16 11.3 0.0 3.0 3 0 0 3 3 3 0 AIG1 family TrwB_AAD_bind PF10412.9 CCC68431.1 - 0.023 13.7 0.4 1.8 7.4 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_25 PF13481.6 CCC68431.1 - 0.026 14.1 0.0 3.7 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF5336 PF17270.2 CCC68431.1 - 0.034 13.8 1.2 0.1 12.2 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5336) AAA_21 PF13304.6 CCC68431.1 - 0.04 13.7 4.6 12 5.6 0.1 3.5 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 CCC68431.1 - 0.052 13.8 0.6 9 6.5 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase HK PF02110.15 CCC68431.1 - 0.055 12.9 1.2 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family Root_cap PF06830.11 CCC68431.1 - 0.061 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Root cap IstB_IS21 PF01695.17 CCC68431.1 - 0.068 12.9 0.1 2.8 7.6 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 CCC68431.1 - 0.072 12.8 0.0 7.4 6.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.6 CCC68431.1 - 0.082 12.6 0.5 17 5.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain MeaB PF03308.16 CCC68431.1 - 0.12 11.4 0.0 7.4 5.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB TMEM132D_C PF15706.5 CCC68431.1 - 0.13 12.1 0.3 0.54 10.1 0.1 2.1 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term AAA_22 PF13401.6 CCC68431.1 - 0.13 12.5 1.6 8.6 6.6 0.1 3.0 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 CCC68431.1 - 0.13 11.2 1.1 1.3 8.0 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein WRW PF10206.9 CCC68431.1 - 0.15 12.5 0.7 0.9 9.9 0.0 2.7 2 0 0 2 2 1 0 Mitochondrial F1F0-ATP synthase, subunit f Dynamin_N PF00350.23 CCC68431.1 - 0.2 11.7 3.1 1.7 8.7 0.0 2.9 3 0 0 3 3 3 0 Dynamin family NACHT PF05729.12 CCC68431.1 - 0.29 11.0 3.4 4.8 7.1 0.1 3.3 3 0 0 3 3 3 0 NACHT domain Rgp1 PF08737.10 CCC68433.1 - 3e-106 356.1 12.3 3e-106 356.1 12.3 1.7 2 0 0 2 2 2 1 Rgp1 G10 PF01125.17 CCC68433.1 - 0.0065 16.2 0.3 0.022 14.5 0.3 1.9 2 0 0 2 2 2 1 G10 protein efThoc1 PF11957.8 CCC68434.1 - 2.5e-115 386.0 34.9 3.4e-115 385.5 34.9 1.2 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor MTS PF05175.14 CCC68437.1 - 9.8e-10 38.2 0.0 1.9e-09 37.3 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.13 CCC68437.1 - 0.00031 20.2 0.0 0.00062 19.3 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 CCC68437.1 - 0.01 16.5 0.0 0.021 15.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CCC68437.1 - 0.019 14.8 0.0 0.041 13.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_33 PF10017.9 CCC68437.1 - 0.029 13.5 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Met_10 PF02475.16 CCC68437.1 - 0.045 13.5 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein AbrB_C PF18277.1 CCC68437.1 - 0.06 13.0 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 AbrB C-terminal domain UPF0020 PF01170.18 CCC68437.1 - 0.077 12.7 0.0 0.17 11.6 0.0 1.5 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 rRNA_methylase PF06962.12 CCC68437.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Putative rRNA methylase Dopey_N PF04118.14 CCC68438.1 - 1.5e-110 369.2 2.1 1.5e-110 369.2 2.1 3.0 3 0 0 3 3 3 2 Dopey, N-terminal UME PF08064.13 CCC68438.1 - 0.061 13.2 0.8 38 4.3 0.1 3.9 3 0 0 3 3 3 0 UME (NUC010) domain Casein PF00363.18 CCC68438.1 - 0.095 13.1 0.1 0.29 11.5 0.1 1.8 1 0 0 1 1 1 0 Casein WD40 PF00400.32 CCC68439.1 - 2.9e-15 56.4 12.5 0.0015 19.4 0.1 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC68439.1 - 0.0017 18.6 0.4 0.95 9.8 0.1 3.9 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Asp PF00026.23 CCC68440.1 - 1.7e-71 241.2 4.1 5.9e-71 239.5 4.1 1.8 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCC68440.1 - 1.7e-08 34.9 0.5 8.8e-08 32.6 0.5 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CCC68440.1 - 0.0033 18.0 1.0 41 4.9 0.0 3.8 3 1 0 3 3 3 3 Aspartyl protease TFIID_20kDa PF03847.13 CCC68441.1 - 9.6e-32 109.3 0.5 9.6e-32 109.3 0.5 2.3 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A Histone PF00125.24 CCC68441.1 - 0.00072 19.9 0.0 0.00072 19.9 0.0 4.5 3 2 0 3 3 3 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCC68441.1 - 0.024 14.9 0.0 0.085 13.2 0.0 2.0 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Zip PF02535.22 CCC68442.1 - 2.7e-79 266.8 3.2 3.2e-79 266.6 3.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2512 PF10710.9 CCC68442.1 - 0.093 12.4 1.9 0.4 10.3 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2512) DHHC PF01529.20 CCC68443.1 - 1e-28 100.1 15.6 1e-28 100.1 15.6 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF4064 PF13273.6 CCC68443.1 - 0.034 14.4 3.9 0.28 11.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) zf-C2H2 PF00096.26 CCC68444.1 - 4.1e-10 39.5 13.8 0.0025 18.2 0.9 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC68444.1 - 5.3e-05 23.5 13.6 0.0047 17.3 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC68444.1 - 0.0015 19.2 12.5 0.62 11.0 0.8 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger CASP_C PF08172.12 CCC68444.1 - 0.0036 16.7 1.7 0.0063 15.9 1.7 1.4 1 0 0 1 1 1 1 CASP C terminal HIGH_NTase1 PF05636.11 CCC68444.1 - 0.021 14.0 0.8 0.033 13.4 0.8 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase SKA1 PF07160.12 CCC68444.1 - 0.022 14.6 5.7 0.047 13.5 5.7 1.5 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 DUF892 PF05974.12 CCC68444.1 - 0.045 13.8 3.2 0.077 13.0 3.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF892) Phage_GPO PF05929.11 CCC68444.1 - 0.16 11.6 4.3 0.25 11.0 4.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AT_hook PF02178.19 CCC68444.1 - 0.19 11.7 5.7 0.48 10.5 5.7 1.7 1 0 0 1 1 1 0 AT hook motif LMBR1 PF04791.16 CCC68444.1 - 0.23 10.3 2.6 0.32 9.9 2.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2951 PF11166.8 CCC68444.1 - 0.36 11.1 4.8 0.95 9.7 4.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) zf-C2H2_jaz PF12171.8 CCC68444.1 - 1.2 9.6 6.6 57 4.2 0.1 3.9 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCC68444.1 - 1.3 9.1 3.3 3.9 7.6 0.0 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger PP2C_C PF07830.13 CCC68444.1 - 1.8 9.1 5.8 5.8 7.5 5.8 1.8 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain zf_ZIC PF18366.1 CCC68444.1 - 3.5 7.8 4.8 4.5 7.5 0.1 3.0 2 1 1 3 3 3 0 Zic proteins zinc finger domain Choline_kinase PF01633.20 CCC68445.1 - 4.6e-51 173.4 3.2 6.5e-51 172.9 3.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CCC68445.1 - 0.0016 18.4 0.0 0.008 16.1 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family 2-oxoacid_dh PF00198.23 CCC68446.1 - 3.8e-81 272.0 0.1 5.5e-81 271.4 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CCC68446.1 - 4e-16 58.6 0.7 7.3e-16 57.8 0.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.6 CCC68446.1 - 0.0005 20.7 0.1 0.0043 17.7 0.1 2.2 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.19 CCC68446.1 - 0.00097 19.0 0.1 0.0025 17.7 0.1 1.7 1 1 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.6 CCC68446.1 - 0.0024 17.7 0.0 0.041 13.7 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like RnfC_N PF13375.6 CCC68446.1 - 0.018 15.0 0.2 0.064 13.2 0.0 2.1 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain HlyD_D23 PF16576.5 CCC68446.1 - 0.099 11.8 0.7 0.22 10.7 0.6 1.8 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Mcp5_PH PF12814.7 CCC68447.1 - 1.1e-41 141.7 0.1 1.1e-41 141.7 0.1 2.7 3 0 0 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology PH PF00169.29 CCC68447.1 - 0.002 18.6 0.0 0.0073 16.8 0.0 2.1 1 0 0 1 1 1 1 PH domain zf-CCCH PF00642.24 CCC68448.1 - 1.1e-15 57.0 18.6 5.5e-09 35.7 4.3 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCC68448.1 - 2.6e-06 27.3 22.4 0.0004 20.3 6.2 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 CCC68448.1 - 3.1e-05 23.6 17.5 9.9e-05 22.0 2.7 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CCC68448.1 - 0.07 13.8 20.0 0.081 13.6 9.3 2.5 1 1 1 2 2 2 0 Torus domain Defensin_int PF17858.1 CCC68448.1 - 0.29 11.2 1.2 0.61 10.1 0.6 1.8 2 0 0 2 2 2 0 Platypus intermediate defensin-like peptide zf-CCCH_2 PF14608.6 CCC68448.1 - 0.41 11.2 16.5 1.1 9.9 2.6 2.4 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RWD PF05773.22 CCC68449.1 - 7e-25 87.6 1.4 2.5e-24 85.8 1.4 2.0 1 1 0 1 1 1 1 RWD domain DFRP_C PF16543.5 CCC68449.1 - 0.00025 21.4 3.1 0.00025 21.4 3.1 2.4 2 1 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 DUF4390 PF14334.6 CCC68449.1 - 0.034 13.6 0.0 0.092 12.2 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4390) UEV PF05743.13 CCC68449.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 UEV domain ENTH PF01417.20 CCC68450.1 - 9.1e-33 113.0 0.3 3e-32 111.3 0.0 2.0 2 0 0 2 2 2 1 ENTH domain Synaphin PF05835.12 CCC68450.1 - 0.0051 17.1 4.3 0.0051 17.1 4.3 1.7 2 0 0 2 2 2 1 Synaphin protein FIN1 PF17300.2 CCC68451.1 - 1.6e-71 240.6 16.3 1.9e-71 240.4 16.3 1.0 1 0 0 1 1 1 1 Filaments in between nuclei protein-1 WD40_alt PF14077.6 CCC68451.1 - 0.013 15.3 0.1 0.76 9.7 0.0 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif HSBP1 PF06825.12 CCC68451.1 - 0.043 13.7 1.0 0.096 12.6 1.0 1.5 1 0 0 1 1 1 0 Heat shock factor binding protein 1 HLH PF00010.26 CCC68451.1 - 0.068 13.1 0.5 0.21 11.6 0.5 1.9 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain UPF0184 PF03670.13 CCC68451.1 - 0.12 12.7 1.7 0.22 11.9 0.6 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Mer2 PF09074.10 CCC68451.1 - 0.13 12.1 6.9 0.028 14.2 3.6 1.5 2 0 0 2 2 2 0 Mer2 adh_short PF00106.25 CCC68452.1 - 3.1e-05 23.5 0.0 6.5e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase Zn_ribbon_17 PF17120.5 CCC68453.1 - 9.1e-20 70.0 15.0 2.1e-19 68.9 15.0 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CCC68453.1 - 3e-09 37.3 20.4 2.4e-05 25.0 0.4 6.3 5 0 0 5 5 5 2 WD domain, G-beta repeat zf-rbx1 PF12678.7 CCC68453.1 - 0.0092 16.2 8.6 0.022 15.0 8.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CCC68453.1 - 0.016 15.5 9.0 0.039 14.3 9.0 1.7 1 0 0 1 1 1 0 Ring finger domain RWD PF05773.22 CCC68453.1 - 0.048 13.9 1.4 0.072 13.4 0.1 2.0 2 0 0 2 2 2 0 RWD domain C1_2 PF03107.16 CCC68453.1 - 0.09 13.1 4.1 0.27 11.6 4.1 1.8 1 0 0 1 1 1 0 C1 domain zf-C3HC4_2 PF13923.6 CCC68453.1 - 0.1 12.5 7.8 0.27 11.1 7.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) EPSP_synthase PF00275.20 CCC68454.1 - 3.1e-142 474.1 0.1 4.3e-142 473.7 0.1 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CCC68454.1 - 2.6e-99 331.7 0.0 4.2e-99 330.9 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 CCC68454.1 - 8.8e-06 25.6 0.0 1.9e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Abhydrolase_1 PF00561.20 CCC68455.1 - 1.6e-17 64.1 0.0 9.6e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCC68455.1 - 1.5e-11 45.3 0.0 2.8e-11 44.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCC68455.1 - 8.8e-10 38.3 0.0 1.2e-07 31.3 0.0 3.0 2 1 1 3 3 3 2 Serine aminopeptidase, S33 DUF915 PF06028.11 CCC68455.1 - 1e-07 31.6 1.2 7.7e-07 28.7 1.2 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 CCC68455.1 - 4.1e-06 26.6 0.0 8.6e-06 25.5 0.0 1.7 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase Esterase PF00756.20 CCC68455.1 - 0.0025 17.5 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 CCC68455.1 - 0.0026 17.5 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 CCC68455.1 - 0.0046 17.1 0.0 0.018 15.2 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.13 CCC68455.1 - 0.006 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_3 PF07859.13 CCC68455.1 - 0.0079 16.1 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 CCC68455.1 - 0.014 15.3 0.0 0.58 10.1 0.0 2.4 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase2 PF12740.7 CCC68455.1 - 0.047 12.6 0.0 0.088 11.7 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Ndr PF03096.14 CCC68455.1 - 0.051 12.3 0.0 0.16 10.6 0.0 1.9 2 0 0 2 2 2 0 Ndr family Chlorophyllase PF07224.11 CCC68455.1 - 0.061 12.3 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase eRF1_1 PF03463.15 CCC68455.1 - 0.073 13.1 0.1 0.14 12.2 0.1 1.3 1 0 0 1 1 1 0 eRF1 domain 1 DUF2841 PF11001.8 CCC68456.1 - 2e-35 121.5 1.7 4e-35 120.6 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) HLH PF00010.26 CCC68457.1 - 0.065 13.2 0.7 0.11 12.4 0.7 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Pkinase PF00069.25 CCC68458.1 - 2.5e-68 230.3 3.8 2e-63 214.3 0.4 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68458.1 - 3.4e-38 131.4 0.6 1.1e-36 126.5 0.6 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CCC68458.1 - 4.6e-16 58.3 0.5 1.1e-15 57.1 0.1 1.9 2 0 0 2 2 2 1 Kinase associated domain 1 Kinase-like PF14531.6 CCC68458.1 - 2e-09 37.2 0.0 3.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 CCC68458.1 - 4.6e-06 26.1 0.2 1e-05 25.0 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CCC68458.1 - 0.00076 18.5 0.2 0.00076 18.5 0.2 2.8 3 0 0 3 3 3 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CCC68458.1 - 0.0036 16.1 0.0 0.0036 16.1 0.0 3.3 3 1 0 3 3 2 1 Fungal protein kinase APH PF01636.23 CCC68458.1 - 0.0092 15.9 0.1 0.06 13.3 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 CCC68458.1 - 0.017 14.8 0.4 0.053 13.1 0.4 1.8 1 1 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 CCC68458.1 - 0.025 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 CCC68458.1 - 0.036 13.7 0.3 1.2 8.8 0.2 2.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CBFD_NFYB_HMF PF00808.23 CCC68459.1 - 5.4e-06 26.6 0.0 1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 CCC68459.1 - 1.1e-05 25.4 1.5 0.00013 22.0 1.5 2.0 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCC68459.1 - 0.00067 20.0 0.0 0.00067 20.0 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TRM PF02005.16 CCC68460.1 - 3.7e-146 487.1 0.2 4.7e-146 486.8 0.2 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 CCC68460.1 - 0.0006 19.6 0.1 0.0024 17.6 0.1 2.0 2 0 0 2 2 2 1 Met-10+ like-protein Rubredoxin_2 PF18073.1 CCC68460.1 - 0.046 13.4 0.8 0.093 12.5 0.8 1.5 1 0 0 1 1 1 0 Rubredoxin metal binding domain DUF2067 PF09840.9 CCC68460.1 - 0.11 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) PrmA PF06325.13 CCC68460.1 - 0.14 11.5 0.6 0.25 10.7 0.6 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PDH_E1_M PF17831.1 CCC68460.1 - 0.19 11.2 0.0 12 5.3 0.0 2.3 1 1 1 2 2 2 0 Pyruvate dehydrogenase E1 component middle domain ANAPC4 PF12896.7 CCC68463.1 - 8e-35 120.2 6.8 8e-35 120.2 6.8 2.5 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 4 DUF1910 PF08928.10 CCC68463.1 - 0.078 13.0 0.6 0.24 11.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) RUN PF02759.19 CCC68463.1 - 0.21 11.6 1.3 0.39 10.7 0.1 2.2 2 2 0 2 2 2 0 RUN domain SUI1 PF01253.22 CCC68464.1 - 6.3e-20 71.5 0.0 2.2e-19 69.8 0.0 2.0 1 0 0 1 1 1 1 Translation initiation factor SUI1 Pre-PUA PF17832.1 CCC68464.1 - 3.8e-08 33.9 0.4 6.1e-07 30.0 0.4 2.7 2 1 0 2 2 2 1 Pre-PUA-like domain SWIB PF02201.18 CCC68464.1 - 0.00072 19.4 0.1 0.0042 16.9 0.1 2.2 2 0 0 2 2 2 1 SWIB/MDM2 domain Kin17_mid PF10357.9 CCC68464.1 - 0.11 12.5 3.9 0.54 10.2 0.0 2.7 3 0 0 3 3 3 0 Domain of Kin17 curved DNA-binding protein E7 PF00527.18 CCC68464.1 - 0.63 10.3 4.3 38 4.6 2.9 2.5 2 0 0 2 2 2 0 E7 protein, Early protein Ribosomal_L1 PF00687.21 CCC68465.1 - 8.6e-28 97.5 0.2 1e-27 97.2 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF3216 PF11505.8 CCC68465.1 - 0.1 12.8 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) Ribosomal_L34 PF00468.17 CCC68466.1 - 5.8e-18 64.6 4.2 5.8e-18 64.6 4.2 1.7 1 1 1 2 2 2 1 Ribosomal protein L34 Securin PF04856.13 CCC68467.1 - 3.9e-24 85.9 15.3 1.7e-12 47.8 2.2 2.1 2 0 0 2 2 2 2 Securin sister-chromatid separation inhibitor Aminotran_1_2 PF00155.21 CCC68468.1 - 6.2e-35 121.0 0.0 9e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_S13_N PF08069.12 CCC68468.1 - 0.018 15.1 0.2 0.058 13.4 0.2 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain Beta_elim_lyase PF01212.21 CCC68468.1 - 0.033 13.5 0.0 0.15 11.3 0.0 1.8 2 0 0 2 2 2 0 Beta-eliminating lyase Ca_bind_SSO6904 PF18249.1 CCC68469.1 - 0.13 12.6 1.2 0.26 11.7 0.1 2.1 2 0 0 2 2 2 0 Calcium binding protein SSO6904 KCNQ2_u3 PF16642.5 CCC68469.1 - 0.49 11.4 3.3 1.7 9.7 3.3 1.8 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 TP53IP5 PF15331.6 CCC68469.1 - 0.76 9.9 4.1 4.5 7.4 4.0 2.2 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 Gaa1 PF04114.14 CCC68470.1 - 1.6e-115 387.0 13.6 3.5e-115 385.9 13.6 1.5 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component FGGY_C PF02782.16 CCC68471.1 - 2.5e-46 157.9 0.1 4.1e-46 157.2 0.1 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CCC68471.1 - 9.4e-22 77.8 0.0 9.7e-21 74.4 0.0 2.4 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.21 CCC68471.1 - 0.00059 19.8 0.0 0.00097 19.1 0.0 1.3 1 0 0 1 1 1 1 Hexokinase BcrAD_BadFG PF01869.20 CCC68471.1 - 0.029 13.9 0.1 0.68 9.4 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family TRAPPC-Trs85 PF12739.7 CCC68472.1 - 2.2e-109 366.2 3.8 3.4e-109 365.5 3.8 1.3 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit EMP70 PF02990.16 CCC68473.1 - 9.4e-181 602.0 17.6 1.6e-180 601.2 17.6 1.4 1 0 0 1 1 1 1 Endomembrane protein 70 Actin PF00022.19 CCC68474.1 - 8.9e-09 34.4 0.1 9.7e-07 27.7 0.0 2.3 1 1 1 2 2 2 2 Actin Serinc PF03348.15 CCC68475.1 - 7.1e-138 460.1 14.2 8.5e-138 459.9 14.2 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) TMEM173 PF15009.6 CCC68475.1 - 1.8 7.6 7.8 0.2 10.7 2.3 1.9 2 0 0 2 2 2 0 Transmembrane protein 173 PH_4 PF15404.6 CCC68476.1 - 4e-78 261.4 1.8 8.7e-78 260.3 0.2 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.6 CCC68476.1 - 1.7e-23 82.0 2.4 2.8e-23 81.3 0.1 2.5 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.29 CCC68476.1 - 0.0068 16.9 11.9 1.2 9.6 0.2 6.2 5 2 1 6 6 6 1 PH domain PH_11 PF15413.6 CCC68476.1 - 0.051 14.0 5.0 0.22 12.0 0.3 3.8 3 0 0 3 3 3 0 Pleckstrin homology domain Ste5_C PF12194.8 CCC68477.1 - 4.1e-85 284.5 0.5 9.5e-85 283.3 0.5 1.6 1 0 0 1 1 1 1 Protein kinase Fus3-binding zf-RING_2 PF13639.6 CCC68477.1 - 0.0038 17.5 4.5 0.0072 16.6 4.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 CCC68477.1 - 0.05 13.6 0.7 0.13 12.3 0.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 CCC68477.1 - 0.061 12.9 0.4 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 CCC68477.1 - 0.12 12.2 1.2 0.26 11.1 1.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4 PF00097.25 CCC68477.1 - 0.87 9.5 3.3 1.2 9.0 2.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 CCC68477.1 - 1.3 9.0 3.6 2.5 8.0 3.6 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.6 CCC68477.1 - 8.7 6.4 6.0 24 5.0 6.0 1.8 1 1 0 1 1 1 0 zinc-RING finger domain Peptidase_M24 PF00557.24 CCC68478.1 - 7e-06 25.9 0.1 1.9e-05 24.4 0.0 1.8 2 1 0 2 2 2 1 Metallopeptidase family M24 COPI_assoc PF08507.10 CCC68479.1 - 4.2e-38 130.3 8.0 4.8e-38 130.1 8.0 1.0 1 0 0 1 1 1 1 COPI associated protein 14-3-3 PF00244.20 CCC68480.1 - 3.9e-106 353.5 4.1 5e-106 353.2 4.1 1.1 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 CCC68480.1 - 0.0045 17.0 0.4 0.012 15.6 0.4 1.7 1 0 0 1 1 1 1 Flagellar protein FlaF MitMem_reg PF13012.6 CCC68480.1 - 0.13 12.7 1.3 0.27 11.6 0.7 2.1 1 1 0 1 1 1 0 Maintenance of mitochondrial structure and function FRG PF08867.11 CCC68480.1 - 0.45 11.5 2.0 0.55 11.2 0.2 2.1 3 1 0 3 3 3 0 FRG domain MCM6_C PF18263.1 CCC68480.1 - 8.1 6.7 9.5 1.4 9.2 0.9 2.8 3 0 0 3 3 3 0 MCM6 C-terminal winged-helix domain Glutaredoxin PF00462.24 CCC68481.1 - 2.6e-17 62.8 0.0 2.8e-16 59.5 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 CCC68481.1 - 3.8e-13 49.3 0.0 9.6e-13 48.0 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 CCC68481.1 - 0.00015 22.0 0.1 0.023 15.0 0.0 2.6 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.21 CCC68481.1 - 0.0031 17.4 0.0 0.028 14.3 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.6 CCC68481.1 - 0.0066 16.9 0.0 0.11 13.0 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain DUF1840 PF08895.11 CCC68481.1 - 0.02 15.2 0.1 0.033 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) OST3_OST6 PF04756.13 CCC68481.1 - 0.049 13.0 0.0 0.054 12.8 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CCC68481.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.6 2 0 0 2 2 2 0 Thioredoxin-like MutS_V PF00488.21 CCC68482.1 - 6.7e-66 221.9 0.2 4.6e-65 219.2 0.2 2.1 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CCC68482.1 - 1.6e-35 123.1 1.9 2.7e-35 122.3 0.7 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CCC68482.1 - 1.1e-32 112.6 0.1 3.3e-32 111.1 0.0 1.9 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 CCC68482.1 - 9.8e-14 51.5 0.8 2.5e-13 50.2 0.8 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 CCC68482.1 - 4.4e-12 46.4 0.0 1.6e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 MutS domain II Med29 PF11568.8 CCC68482.1 - 0.018 15.3 0.3 0.047 13.9 0.3 1.7 1 0 0 1 1 1 0 Mediator complex subunit 29 AAA_27 PF13514.6 CCC68482.1 - 0.029 14.0 0.0 0.072 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCC68482.1 - 0.11 12.3 0.0 0.42 10.4 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain SOGA PF11365.8 CCC68482.1 - 0.11 13.6 0.6 35 5.6 0.1 2.9 2 0 0 2 2 2 0 Protein SOGA GAGE PF05831.11 CCC68482.1 - 0.12 13.0 2.4 0.32 11.5 2.4 1.7 1 0 0 1 1 1 0 GAGE protein GP57 PF17594.2 CCC68482.1 - 0.13 12.0 0.0 0.35 10.7 0.0 1.7 1 0 0 1 1 1 0 Phage Tail fiber assembly helper gene product 57 TAP35_44 PF07265.11 CCC68482.1 - 0.19 11.8 2.7 0.48 10.5 2.7 1.6 1 0 0 1 1 1 0 Tapetum specific protein TAP35/TAP44 AAA_23 PF13476.6 CCC68482.1 - 0.57 10.6 0.0 0.57 10.6 0.0 4.3 3 2 0 3 3 2 0 AAA domain PhoLip_ATPase_C PF16212.5 CCC68484.1 - 4.5e-74 249.3 29.2 4.5e-74 249.3 29.2 2.4 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCC68484.1 - 4.1e-17 61.6 1.2 4.1e-17 61.6 1.2 2.9 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 CCC68484.1 - 2.1e-13 50.2 0.0 1e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCC68484.1 - 2.8e-10 40.8 2.3 3.6e-06 27.4 0.3 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 CCC68484.1 - 4.8e-07 29.5 1.6 5.1e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CCC68484.1 - 0.0026 17.5 0.2 0.0066 16.2 0.2 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UQ_con PF00179.26 CCC68485.1 - 5.1e-47 159.1 0.0 5.8e-47 158.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCC68485.1 - 0.013 15.2 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 CCC68485.1 - 0.015 15.1 0.1 0.03 14.2 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.22 CCC68485.1 - 0.079 13.3 0.1 0.11 12.8 0.1 1.5 1 1 0 1 1 1 0 RWD domain zf-C2H2_jaz PF12171.8 CCC68486.1 - 4.4e-07 30.0 7.1 0.00042 20.5 0.9 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CCC68486.1 - 3.4e-06 27.4 10.6 0.0036 18.0 2.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCC68486.1 - 0.0005 20.4 10.9 0.013 15.9 2.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-Di19 PF05605.12 CCC68486.1 - 0.0031 17.8 6.5 0.0056 17.0 6.5 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CCC68486.1 - 0.023 15.1 12.6 0.13 12.8 3.0 3.1 3 0 0 3 3 3 0 Zinc-finger double domain DUF968 PF06147.11 CCC68486.1 - 0.05 13.9 0.2 0.086 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF968) zf-met PF12874.7 CCC68486.1 - 0.23 11.9 4.3 4.3 7.9 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CCC68486.1 - 0.67 10.3 8.9 3.4 8.0 0.4 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) ABC_tran PF00005.27 CCC68487.1 - 1.5e-35 122.7 0.1 1.5e-16 61.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 CCC68487.1 - 3.6e-15 55.5 4.9 8.8e-15 54.2 4.9 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.6 CCC68487.1 - 2.6e-12 47.2 6.8 0.017 14.9 0.1 4.3 2 2 2 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCC68487.1 - 1.3e-09 37.9 2.2 0.016 14.7 0.2 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain Fer4 PF00037.27 CCC68487.1 - 2.8e-07 30.1 3.8 2.8e-07 30.1 3.8 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 CCC68487.1 - 4.9e-07 29.8 0.5 0.02 14.6 0.1 3.0 2 1 1 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 CCC68487.1 - 7.4e-06 26.0 0.1 0.035 14.0 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CCC68487.1 - 8.6e-06 26.1 0.0 0.0023 18.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCC68487.1 - 1.2e-05 25.7 0.0 0.025 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA PF00004.29 CCC68487.1 - 2.1e-05 25.0 0.1 0.1 13.0 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CCC68487.1 - 0.00013 21.6 0.7 0.39 10.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Rad17 PF03215.15 CCC68487.1 - 0.00014 21.9 0.3 0.38 10.7 0.1 2.7 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_7 PF12775.7 CCC68487.1 - 0.00048 19.7 1.0 0.0033 17.0 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region Fer4_7 PF12838.7 CCC68487.1 - 0.00068 20.2 6.9 0.00068 20.2 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.7 CCC68487.1 - 0.00078 19.4 3.1 0.00078 19.4 3.1 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain NB-ARC PF00931.22 CCC68487.1 - 0.0015 17.8 0.0 0.67 9.1 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.6 CCC68487.1 - 0.0016 18.2 0.2 0.15 11.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCC68487.1 - 0.0022 18.4 0.1 0.61 10.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Fer4_21 PF14697.6 CCC68487.1 - 0.0032 17.6 12.1 0.0076 16.4 12.1 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_24 PF13479.6 CCC68487.1 - 0.0033 17.2 1.0 0.86 9.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 CCC68487.1 - 0.0036 17.2 1.3 0.32 10.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain SRP54 PF00448.22 CCC68487.1 - 0.0036 16.9 3.2 0.12 12.0 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_2 PF12797.7 CCC68487.1 - 0.0056 16.7 0.8 0.0056 16.7 0.8 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_28 PF13521.6 CCC68487.1 - 0.0061 16.8 0.3 2.2 8.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CCC68487.1 - 0.0062 17.1 5.2 0.042 14.3 0.0 2.7 2 1 0 3 3 2 1 AAA domain AAA_33 PF13671.6 CCC68487.1 - 0.0067 16.6 0.3 1.8 8.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain Fer4_10 PF13237.6 CCC68487.1 - 0.0075 16.4 1.6 0.0075 16.4 1.6 2.4 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 CCC68487.1 - 0.0083 16.3 11.4 0.017 15.3 11.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain AAA_14 PF13173.6 CCC68487.1 - 0.009 16.1 0.1 3.5 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCC68487.1 - 0.01 16.4 0.0 8.5 6.9 0.0 2.8 3 0 0 3 3 2 0 AAA domain Fer4_16 PF13484.6 CCC68487.1 - 0.014 16.3 0.2 0.014 16.3 0.2 2.8 2 1 1 3 3 1 0 4Fe-4S double cluster binding domain MMR_HSR1 PF01926.23 CCC68487.1 - 0.025 14.6 0.1 4.4 7.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase VirE PF05272.11 CCC68487.1 - 0.029 14.1 0.0 3.1 7.5 0.0 2.3 2 0 0 2 2 2 0 Virulence-associated protein E AAA_5 PF07728.14 CCC68487.1 - 0.03 14.3 1.4 0.19 11.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.6 CCC68487.1 - 0.033 12.8 0.4 0.086 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain Fer4_17 PF13534.6 CCC68487.1 - 0.042 14.4 0.1 0.042 14.4 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Septin PF00735.18 CCC68487.1 - 0.044 13.0 0.1 1.3 8.2 0.1 2.2 2 0 0 2 2 2 0 Septin TsaE PF02367.17 CCC68487.1 - 0.068 13.2 0.1 0.77 9.8 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DLIC PF05783.11 CCC68487.1 - 0.07 11.9 0.1 0.15 10.9 0.1 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) dNK PF01712.19 CCC68487.1 - 0.08 12.8 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 Deoxynucleoside kinase SbcCD_C PF13558.6 CCC68487.1 - 0.087 13.1 0.1 30 4.9 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_8 PF13183.6 CCC68487.1 - 0.14 12.6 0.1 0.14 12.6 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain TniB PF05621.11 CCC68487.1 - 0.15 11.4 0.0 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Thymidylate_kin PF02223.17 CCC68487.1 - 0.17 11.5 0.7 27 4.4 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase Mg_chelatase PF01078.21 CCC68487.1 - 0.2 11.0 1.1 0.27 10.6 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.15 CCC68487.1 - 0.21 11.5 2.1 2.2 8.1 0.1 2.9 3 0 0 3 3 3 0 NTPase Roc PF08477.13 CCC68487.1 - 0.21 11.8 1.1 1.2 9.4 0.1 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 CCC68487.1 - 0.5 10.1 1.8 0.76 9.5 0.1 2.2 2 0 0 2 2 1 0 Ethanolamine utilisation - propanediol utilisation Fer4_4 PF12800.7 CCC68487.1 - 0.61 10.7 15.0 0.45 11.2 3.0 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain PQ-loop PF04193.14 CCC68488.1 - 8.8e-23 79.9 9.3 3.6e-19 68.3 1.5 2.7 2 0 0 2 2 2 2 PQ loop repeat SPW PF03779.14 CCC68488.1 - 0.046 13.3 8.7 0.094 12.3 4.6 2.6 2 0 0 2 2 2 0 SPW repeat MMR_HSR1_C PF08438.10 CCC68488.1 - 0.058 14.0 0.0 0.097 13.3 0.0 1.3 1 0 0 1 1 1 0 GTPase of unknown function C-terminal ABC2_membrane_5 PF13346.6 CCC68488.1 - 1.9 8.0 21.6 1.1 8.7 12.8 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein YfhO PF09586.10 CCC68488.1 - 2.2 6.4 4.8 8.7 4.4 0.7 2.1 2 0 0 2 2 2 0 Bacterial membrane protein YfhO SPX PF03105.19 CCC68489.1 - 4.8e-05 23.5 0.0 0.11 12.4 0.1 3.0 2 1 0 2 2 2 2 SPX domain Tom22 PF04281.13 CCC68489.1 - 0.053 13.3 0.3 0.28 10.9 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 WSK PF03832.13 CCC68489.1 - 0.87 9.3 5.4 1.8 8.3 5.4 1.5 1 0 0 1 1 1 0 WSK motif ABC2_membrane_3 PF12698.7 CCC68489.1 - 5.5 6.0 17.8 0.13 11.4 9.6 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein Slu7 PF11708.8 CCC68490.1 - 9.7e-17 61.6 13.3 9.7e-17 61.6 13.3 2.6 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.23 CCC68490.1 - 3.7e-06 26.7 1.1 6e-06 26.1 1.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 CCC68490.1 - 0.048 13.4 1.4 0.12 12.1 1.4 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 CCC68490.1 - 0.061 13.2 2.5 0.16 11.9 2.5 1.7 1 0 0 1 1 1 0 Zinc knuckle Prok-RING_1 PF14446.6 CCC68490.1 - 0.072 13.0 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Nop52 PF05997.12 CCC68491.1 - 3.6e-69 232.8 7.0 4.3e-69 232.6 7.0 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 HSNSD PF12062.8 CCC68491.1 - 0.067 11.9 1.7 0.11 11.2 0.1 1.9 2 0 0 2 2 2 0 heparan sulfate-N-deacetylase SecE PF00584.20 CCC68492.1 - 1.4e-12 47.3 0.0 1.8e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Coiled-coil_56 PF09813.9 CCC68492.1 - 0.061 13.4 0.0 0.07 13.2 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 ASFV_p27 PF06556.11 CCC68492.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 IAP-like protein p27 C-terminus DUF846 PF05832.12 CCC68494.1 - 9.3e-47 158.6 5.4 1.1e-46 158.3 5.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) TraL PF07178.11 CCC68494.1 - 2.3 8.7 9.0 17 6.0 0.2 2.2 2 0 0 2 2 2 0 TraL protein Methyltransf_8 PF05148.15 CCC68495.1 - 6.7e-62 209.2 0.0 1.9e-61 207.7 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 CCC68495.1 - 7.7e-09 36.1 0.1 1.9e-07 31.6 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCC68495.1 - 4.2e-06 27.4 0.1 0.0001 22.9 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC68495.1 - 0.021 14.6 0.2 0.67 9.7 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 CCC68495.1 - 0.076 12.6 0.0 5 6.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.6 CCC68495.1 - 3.7 7.5 0.0 3.7 7.5 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Stn1_C PF12659.7 CCC68496.1 - 7.3e-41 138.9 6.0 1.6e-40 137.8 6.0 1.6 1 0 0 1 1 1 1 Telomere capping C-terminal wHTH Stn1 PF10451.9 CCC68496.1 - 3e-38 131.2 0.0 5.6e-38 130.3 0.0 1.3 1 0 0 1 1 1 1 Telomere regulation protein Stn1 DDE_1 PF03184.19 CCC68497.1 - 2.3e-67 226.0 3.4 5.4e-67 224.8 3.4 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.16 CCC68497.1 - 2e-14 53.3 0.2 2e-14 53.3 0.2 2.3 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_ABP1_N PF18107.1 CCC68497.1 - 2.3e-05 24.0 0.4 7.4e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain HTH_32 PF13565.6 CCC68497.1 - 0.073 13.7 0.0 1.1 10.0 0.1 2.6 2 0 0 2 2 2 0 Homeodomain-like domain Clathrin PF00637.20 CCC68498.1 - 5.9e-23 81.3 0.2 5.9e-23 81.3 0.2 2.9 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.32 CCC68498.1 - 0.02 15.8 0.4 0.064 14.1 0.4 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat Imm2 PF14426.6 CCC68498.1 - 0.21 11.7 0.6 13 5.9 0.1 2.7 2 0 0 2 2 2 0 Immunity protein Imm2 Tfb5 PF06331.12 CCC68499.1 - 9.6e-28 96.0 0.2 1.1e-27 95.8 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 YokU PF14122.6 CCC68499.1 - 0.026 14.5 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 YokU-like protein, putative antitoxin Pet100 PF09803.9 CCC68500.1 - 2.5e-10 40.7 0.1 4.1e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 Pet100 ATPase_gene1 PF09527.10 CCC68500.1 - 0.14 12.4 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Histone_HNS PF00816.21 CCC68500.1 - 0.2 12.5 2.0 0.27 12.1 2.0 1.2 1 0 0 1 1 1 0 H-NS histone family Methyltransf_23 PF13489.6 CCC68501.1 - 5.1e-22 78.4 0.0 7.8e-22 77.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC68501.1 - 8.3e-15 55.2 0.0 1.4e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC68501.1 - 1.9e-14 53.7 0.0 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCC68501.1 - 7.8e-12 45.7 0.0 1.5e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC68501.1 - 8.2e-11 42.5 0.0 1.9e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 CCC68501.1 - 2.4e-07 30.4 0.0 3.6e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 CCC68501.1 - 1.2e-05 25.0 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) CMAS PF02353.20 CCC68501.1 - 1.9e-05 24.1 0.0 2.6e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CCC68501.1 - 3.3e-05 23.5 0.0 7.8e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain DREV PF05219.12 CCC68501.1 - 0.00022 20.4 0.0 0.00036 19.7 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_32 PF13679.6 CCC68501.1 - 0.00057 19.9 0.0 0.00087 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CCC68501.1 - 0.0012 18.5 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_9 PF08003.11 CCC68501.1 - 0.0029 16.6 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CheR PF01739.18 CCC68501.1 - 0.0052 16.3 0.0 0.068 12.6 0.0 2.2 1 1 0 2 2 2 1 CheR methyltransferase, SAM binding domain AviRa PF11599.8 CCC68501.1 - 0.038 13.4 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa RrnaAD PF00398.20 CCC68501.1 - 0.07 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Nrap_D2 PF17403.2 CCC68501.1 - 0.13 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain Trypan_PARP PF05887.11 CCC68502.1 - 0.018 15.0 0.2 0.024 14.6 0.2 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SWIM PF04434.17 CCC68502.1 - 0.24 11.1 4.5 0.98 9.2 0.0 2.4 2 0 0 2 2 2 0 SWIM zinc finger ATPase PF06745.13 CCC68504.1 - 7.2e-07 28.8 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 KaiC ATPase_2 PF01637.18 CCC68504.1 - 4.6e-06 26.7 0.3 1.3e-05 25.3 0.1 1.8 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Rad51 PF08423.11 CCC68504.1 - 1.2e-05 24.7 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Rad51 AAA_24 PF13479.6 CCC68504.1 - 0.0018 18.1 0.0 0.004 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CCC68504.1 - 0.01 15.6 0.0 0.12 12.1 0.0 2.5 3 0 0 3 3 3 0 IstB-like ATP binding protein DnaB_C PF03796.15 CCC68504.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain Glyco_transf_20 PF00982.21 CCC68505.1 - 6.2e-150 500.0 0.4 2.2e-149 498.2 0.4 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 CCC68505.1 - 3.6e-78 261.9 0.0 6.4e-78 261.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase PAP2_3 PF14378.6 CCC68507.1 - 2.8e-12 46.7 21.0 1.7e-10 40.9 5.8 3.1 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 CCC68507.1 - 1.2e-08 34.8 13.9 4.2e-06 26.6 0.5 3.4 3 1 0 3 3 3 2 PAP2 superfamily DUF1230 PF06799.11 CCC68507.1 - 0.15 12.2 2.6 0.21 11.7 0.3 2.2 1 1 1 2 2 2 0 Conserved in the green lineage and diatoms 27 Acetyltransf_1 PF00583.25 CCC68508.1 - 2.8e-19 69.5 0.0 3.7e-19 69.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCC68508.1 - 1.5e-11 44.3 0.0 2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCC68508.1 - 4.2e-06 27.1 0.0 6.3e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CCC68508.1 - 1.9e-05 24.7 0.0 0.00012 22.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 CCC68508.1 - 0.0065 16.6 0.0 0.042 14.0 0.0 2.1 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 CCC68508.1 - 0.016 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_8 PF13523.6 CCC68508.1 - 0.018 14.7 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCC68508.1 - 0.057 13.4 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Hyphal_reg_CWP PF11765.8 CCC68509.1 - 1.8e-22 79.7 5.6 1.8e-22 79.7 5.6 2.3 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal SRP72 PF08492.12 CCC68510.1 - 0.1 13.1 4.3 0.18 12.3 4.3 1.4 1 0 0 1 1 1 0 SRP72 RNA-binding domain Neur_chan_memb PF02932.16 CCC68510.1 - 0.13 12.3 0.1 0.14 12.2 0.1 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UCH PF00443.29 CCC68512.1 - 2.6e-62 210.6 0.9 2.6e-62 210.6 0.9 2.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCC68512.1 - 6.5e-22 78.5 3.5 8.5e-22 78.1 0.2 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.20 CCC68512.1 - 7.7e-09 36.0 0.0 1.9e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain zf-MIZ PF02891.20 CCC68512.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.3 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger BSD PF03909.17 CCC68513.1 - 2.6e-16 59.3 0.0 6.3e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 BSD domain hDGE_amylase PF14701.6 CCC68513.1 - 2.5 7.1 11.0 0.085 11.9 3.7 1.9 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Y_phosphatase2 PF03162.13 CCC68514.1 - 7.7e-56 188.2 1.5 1.1e-55 187.6 1.5 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCC68514.1 - 0.015 15.3 0.0 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 Tyrosine phosphatase family RPAP2_Rtr1 PF04181.13 CCC68515.1 - 4.7e-12 46.0 1.7 2e-11 44.0 1.7 2.0 1 1 0 1 1 1 1 Rtr1/RPAP2 family Complex1_LYR PF05347.15 CCC68516.1 - 0.031 14.3 0.8 0.031 14.3 0.8 2.5 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Cofilin_ADF PF00241.20 CCC68517.1 - 1.6e-16 60.2 0.0 2e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Myb_Cef PF11831.8 CCC68517.1 - 0.05 13.2 0.4 0.091 12.3 0.4 1.4 1 0 0 1 1 1 0 pre-mRNA splicing factor component Aminotran_1_2 PF00155.21 CCC68518.1 - 4.5e-67 226.8 0.0 5.4e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CCC68518.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V ABC_tran PF00005.27 CCC68519.1 - 1.3e-23 84.0 0.0 8.4e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CCC68519.1 - 6.9e-07 29.4 0.3 0.009 15.8 0.0 2.6 2 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCC68519.1 - 0.0008 19.1 0.0 0.0018 18.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 CCC68519.1 - 0.011 16.0 0.1 0.46 10.8 0.0 2.6 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.6 CCC68519.1 - 0.035 14.4 0.1 0.39 11.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain Ploopntkinase1 PF18748.1 CCC68519.1 - 0.065 12.7 0.0 0.27 10.7 0.0 1.9 2 0 0 2 2 2 0 P-loop Nucleotide Kinase1 T2SSE PF00437.20 CCC68519.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 CCC68519.1 - 0.28 11.7 0.1 0.28 11.7 0.1 2.6 3 1 0 3 3 3 0 AAA domain zf-C2H2_jaz PF12171.8 CCC68520.1 - 2.6e-07 30.8 5.1 0.00074 19.7 0.3 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CCC68520.1 - 9e-05 23.0 14.6 0.0059 17.3 1.7 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.12 CCC68520.1 - 0.00066 19.9 5.6 0.0012 19.1 5.6 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.6 CCC68520.1 - 0.16 12.4 16.2 0.13 12.8 3.0 3.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-C2H2 PF00096.26 CCC68520.1 - 0.37 11.4 14.2 1.3 9.6 1.4 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 CCC68520.1 - 0.6 10.5 7.2 8.9 6.7 0.2 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Acid_PPase PF12689.7 CCC68521.1 - 1.1e-45 155.5 0.0 1.3e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Tk-SP_N-pro PF18237.1 CCC68521.1 - 0.038 14.0 0.0 5.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Tk-SP N-propeptide domain zf-UBR PF02207.20 CCC68522.1 - 8.1e-09 35.5 12.5 8.1e-09 35.5 12.5 2.7 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) UAF_Rrn10 PF05234.11 CCC68524.1 - 3.7e-45 153.0 0.1 4.6e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 UAF complex subunit Rrn10 zf-C2H2_10 PF16588.5 CCC68525.1 - 5.7e-15 54.7 5.7 9e-15 54.1 5.7 1.3 1 0 0 1 1 1 1 C2H2 zinc-finger Cep57_MT_bd PF06657.13 CCC68525.1 - 0.0077 16.7 0.3 0.1 13.0 0.2 2.2 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 zf-CCHC_4 PF14392.6 CCC68525.1 - 0.078 12.7 1.8 0.35 10.6 1.4 2.0 2 0 0 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 CCC68525.1 - 0.084 13.0 1.0 0.14 12.3 1.0 1.3 1 0 0 1 1 1 0 PHD-finger LSM PF01423.22 CCC68526.1 - 3.6e-18 65.0 0.2 4.6e-18 64.7 0.2 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CCC68526.1 - 0.065 12.9 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Hfq protein DUF4443 PF14544.6 CCC68527.1 - 0.064 13.5 0.1 0.1 12.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4443) YmgB PF10798.8 CCC68527.1 - 0.09 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR EMP24_GP25L PF01105.24 CCC68528.1 - 3.9e-42 144.3 0.1 4.5e-42 144.1 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD POC3_POC4 PF10448.9 CCC68528.1 - 0.025 14.6 0.1 0.037 14.1 0.1 1.3 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 Metallophos PF00149.28 CCC68529.1 - 2.7e-40 139.1 0.1 3.6e-40 138.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCC68529.1 - 1.1e-22 80.2 1.5 1.8e-22 79.5 0.5 1.9 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Kelch_6 PF13964.6 CCC68530.1 - 4.5e-17 61.7 2.4 1.4e-08 34.7 0.0 5.7 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 CCC68530.1 - 1.3e-15 57.1 1.4 1.9e-05 24.6 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 CCC68530.1 - 3.1e-12 45.9 0.2 2.8e-05 23.6 0.1 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 CCC68530.1 - 1.9e-08 34.0 0.2 0.0035 17.3 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 CCC68530.1 - 2.3e-08 34.1 0.0 0.061 13.6 0.1 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CCC68530.1 - 0.0001 22.2 0.0 0.023 14.7 0.0 3.5 3 0 0 3 3 3 1 Kelch motif WD40 PF00400.32 CCC68531.1 - 3.3e-16 59.4 0.4 0.0025 18.6 0.0 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat EFTUD2 PF16004.5 CCC68531.1 - 0.41 11.2 5.2 1.3 9.6 2.7 2.6 3 0 0 3 3 3 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Ribosomal_S26e PF01283.19 CCC68532.1 - 7.5e-51 171.1 10.5 8.7e-51 170.9 10.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Pkinase PF00069.25 CCC68533.1 - 1.2e-75 254.3 0.1 1.4e-75 254.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68533.1 - 4.1e-50 170.5 0.0 5.3e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC68533.1 - 1.7e-07 30.8 0.0 2.5e-06 27.1 0.0 2.4 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CCC68533.1 - 0.014 14.8 0.1 0.03 13.7 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCC68533.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Fungal_trans PF04082.18 CCC68534.1 - 2.1e-67 227.0 2.6 2.1e-67 227.0 2.6 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.26 CCC68534.1 - 2.9e-09 36.9 10.1 0.00046 20.5 3.7 3.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC68534.1 - 1.7e-05 25.2 7.4 0.023 15.5 2.5 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger Androgen_recep PF02166.16 CCC68534.1 - 0.00038 19.4 1.1 0.00079 18.4 1.1 1.4 1 0 0 1 1 1 1 Androgen receptor zf-C2H2_6 PF13912.6 CCC68534.1 - 1.2 9.2 5.0 11 6.2 0.8 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger MRG PF05712.13 CCC68535.1 - 5.9e-42 143.2 4.6 5.9e-42 143.2 4.6 1.8 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.8 CCC68535.1 - 4.9e-07 29.5 0.1 5.1e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain DUF4679 PF15728.5 CCC68535.1 - 0.048 12.7 9.4 0.063 12.3 9.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) Pet100 PF09803.9 CCC68535.1 - 0.081 13.5 0.9 0.25 11.9 0.9 1.9 1 0 0 1 1 1 0 Pet100 Pkinase PF00069.25 CCC68536.1 - 1.7e-22 80.0 0.0 3.2e-22 79.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68536.1 - 1e-11 44.6 0.0 1.6e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC68536.1 - 7.6e-06 24.9 0.1 7.6e-06 24.9 0.1 2.1 2 0 0 2 2 2 1 Fungal protein kinase HECT PF00632.25 CCC68538.1 - 5.5e-94 315.1 0.0 7.4e-94 314.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.26 CCC68538.1 - 4.2e-34 116.3 22.8 4.3e-12 45.9 1.3 4.2 4 0 0 4 4 4 3 WW domain C2 PF00168.30 CCC68538.1 - 5.4e-19 68.4 0.1 1.6e-18 66.9 0.1 1.8 1 0 0 1 1 1 1 C2 domain Ribosomal_S8e PF01201.22 CCC68539.1 - 8e-46 155.6 0.1 1.3e-45 154.9 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein S8e DUF4464 PF14713.6 CCC68539.1 - 0.31 10.6 3.3 0.51 9.9 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) Sas10_Utp3 PF04000.15 CCC68540.1 - 1.1e-12 48.4 1.2 1.1e-12 48.4 1.2 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family Vpu PF00558.19 CCC68540.1 - 1.1 9.1 4.2 4 7.3 4.2 2.0 1 0 0 1 1 1 0 Vpu protein Vfa1 PF08432.10 CCC68541.1 - 1.1e-41 143.2 7.4 1.2e-41 143.0 7.4 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DinB_2 PF12867.7 CCC68541.1 - 0.16 12.5 0.1 0.45 11.0 0.1 1.8 1 1 0 1 1 1 0 DinB superfamily Pkinase PF00069.25 CCC68542.1 - 7.4e-51 173.0 0.3 3.9e-50 170.7 0.3 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68542.1 - 2.2e-25 89.4 0.2 2.8e-24 85.8 0.1 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC68542.1 - 4.2e-05 23.0 2.9 0.011 15.0 0.0 3.4 4 0 0 4 4 4 2 Kinase-like APH PF01636.23 CCC68542.1 - 0.033 14.1 0.0 0.36 10.7 0.0 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family ArfGap PF01412.18 CCC68543.1 - 6e-22 77.9 1.6 6e-22 77.9 1.6 2.2 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf UBA PF00627.31 CCC68543.1 - 0.00024 20.9 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain DUF722 PF05263.11 CCC68543.1 - 0.15 12.3 1.4 0.33 11.2 1.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF722) zf-C2H2 PF00096.26 CCC68544.1 - 1.6e-12 47.1 13.3 2.5e-06 27.6 2.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC68544.1 - 1.4e-09 37.9 10.5 0.00021 21.8 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCC68544.1 - 2.8e-08 33.8 8.0 0.0013 18.9 0.8 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CCC68544.1 - 3.5e-07 30.3 12.8 2.1e-06 27.9 2.6 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-Di19 PF05605.12 CCC68544.1 - 7.6e-05 22.9 3.1 0.00015 22.0 3.1 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CCC68544.1 - 0.00056 19.8 9.0 0.013 15.5 1.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCC68544.1 - 0.0089 16.4 7.1 1.5 9.3 2.3 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type PyrI_C PF02748.15 CCC68544.1 - 0.011 15.6 1.0 0.4 10.6 0.1 2.8 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-H2C2_5 PF13909.6 CCC68544.1 - 0.06 13.1 4.0 2.5 7.9 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 CCC68544.1 - 0.06 13.7 6.1 1.8 9.0 0.5 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 CCC68544.1 - 0.16 12.0 14.7 0.91 9.6 3.3 3.3 2 1 1 3 3 2 0 BED zinc finger zf-C2HE PF16278.5 CCC68544.1 - 0.29 11.6 8.4 5.9 7.4 1.7 2.9 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2HC_2 PF13913.6 CCC68544.1 - 1.8 8.6 6.3 6.1 6.9 1.9 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DUF629 PF04780.12 CCC68544.1 - 1.9 6.9 6.6 6.8 5.1 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF629) S_tail_recep_bd PF14928.6 CCC68544.1 - 2.1 9.0 7.2 0.64 10.7 0.8 2.8 2 0 0 2 2 2 0 Short tail fibre protein receptor-binding domain zf_C2H2_ZHX PF18387.1 CCC68544.1 - 2.4 7.9 5.0 6.5 6.5 0.1 2.8 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain Mito_carr PF00153.27 CCC68546.1 - 6.6e-69 227.9 1.2 1e-23 83.0 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCC68546.1 - 0.0018 17.5 0.4 0.47 9.6 0.0 3.3 2 1 1 3 3 3 2 Gammaproteobacterial serine protease EF-hand_7 PF13499.6 CCC68546.1 - 0.0048 17.3 2.7 1.7 9.1 0.4 4.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 CCC68546.1 - 0.0063 16.3 0.5 1.3 8.9 0.0 4.0 4 0 0 4 4 4 1 EF-hand domain pair BTHB PF18410.1 CCC68546.1 - 0.1 12.4 0.2 7.9 6.4 0.1 2.9 2 0 0 2 2 2 0 Basic tilted helix bundle domain DEAD PF00270.29 CCC68547.1 - 3.9e-43 147.3 0.6 1.2e-42 145.7 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC68547.1 - 4.1e-32 110.8 0.6 1.8e-28 99.1 0.0 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCC68547.1 - 2.2e-06 27.8 0.9 1.7e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCC68547.1 - 0.12 12.6 1.6 1.9 8.7 1.6 2.4 1 1 0 1 1 1 0 AAA domain Mss4 PF04421.13 CCC68548.1 - 2.3e-19 69.3 0.0 3.4e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Mss4 protein eIF-6 PF01912.18 CCC68549.1 - 9.7e-82 273.1 0.2 1.2e-81 272.8 0.2 1.1 1 0 0 1 1 1 1 eIF-6 family zf-C2H2 PF00096.26 CCC68550.1 - 0.00084 19.7 1.7 0.00084 19.7 1.7 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC68550.1 - 0.0028 18.0 3.1 0.0028 18.0 3.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC68550.1 - 0.012 16.4 1.6 0.012 16.4 1.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.7 CCC68550.1 - 0.013 15.8 0.3 0.013 15.8 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CCC68551.1 - 4.9e-09 36.1 6.2 0.0011 19.3 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC68551.1 - 4e-06 27.2 5.9 0.016 16.0 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCC68551.1 - 9.4e-05 22.7 0.2 9.4e-05 22.7 0.2 3.1 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.7 CCC68551.1 - 0.0047 17.3 4.8 0.014 15.8 0.3 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 CCC68551.1 - 0.064 13.9 3.4 0.15 12.7 0.1 2.7 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CCC68551.1 - 0.065 13.5 4.4 0.29 11.5 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.6 CCC68551.1 - 5.5 6.8 10.7 8.1 6.3 1.1 3.5 4 0 0 4 4 4 0 C2H2-type zinc-finger domain B12D PF06522.11 CCC68552.1 - 6.3e-05 22.7 0.0 7.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit MmgE_PrpD PF03972.14 CCC68553.1 - 7.4e-139 463.1 0.0 9.1e-139 462.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Nic96 PF04097.14 CCC68554.1 - 3.4e-200 666.7 9.3 5.4e-200 666.0 9.3 1.3 1 0 0 1 1 1 1 Nup93/Nic96 NTS_2 PF15448.6 CCC68554.1 - 0.15 12.5 0.7 34 4.9 0.1 3.2 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein PPI_Ypi1 PF07491.11 CCC68555.1 - 3.2e-21 74.9 11.1 3.2e-21 74.9 11.1 2.0 2 1 0 2 2 2 1 Protein phosphatase inhibitor Cwf_Cwc_15 PF04889.12 CCC68555.1 - 0.0084 15.9 10.5 0.01 15.6 10.5 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein SR-25 PF10500.9 CCC68555.1 - 0.034 13.8 15.3 0.05 13.2 15.3 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CCC68555.1 - 0.77 10.5 14.7 1.4 9.6 14.8 1.5 1 1 0 1 1 1 0 Immortalisation up-regulated protein CDC45 PF02724.14 CCC68555.1 - 1.4 7.1 10.4 1.5 7.0 10.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Nucleo_P87 PF07267.11 CCC68555.1 - 3.2 6.5 10.1 3.8 6.3 10.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 JAB PF01398.21 CCC68556.1 - 6.5e-32 110.0 0.2 6.5e-32 110.0 0.2 2.0 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 CCC68556.1 - 9.9e-11 42.0 1.4 2.4e-10 40.8 1.4 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 CCC68556.1 - 2.4e-07 30.5 0.0 4.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain zf-UBP PF02148.19 CCC68557.1 - 4.1e-09 36.6 0.2 1.1e-08 35.3 0.2 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.29 CCC68557.1 - 2.1e-07 30.7 1.7 5.8e-07 29.3 1.6 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NdhN PF11909.8 CCC68557.1 - 0.025 14.3 0.2 0.044 13.5 0.2 1.3 1 0 0 1 1 1 0 NADH-quinone oxidoreductase cyanobacterial subunit N Peptidase_M24 PF00557.24 CCC68558.1 - 4.5e-56 189.9 0.0 5.9e-56 189.5 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CCC68558.1 - 2.2e-21 75.9 0.0 5e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Citrate_synt PF00285.21 CCC68559.1 - 3.4e-91 306.0 0.0 4e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain CCDC-167 PF15188.6 CCC68560.1 - 0.58 10.5 9.2 1.4 9.3 9.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Hat1_N PF10394.9 CCC68561.1 - 3e-42 144.6 0.8 6.2e-42 143.6 0.8 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 CCC68561.1 - 9e-07 29.1 0.0 1.8e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCC68561.1 - 0.0037 17.7 0.0 0.0072 16.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 CCC68561.1 - 0.055 14.1 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CCC68561.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain KOG2701 PF09762.9 CCC68561.1 - 0.086 13.1 0.2 0.2 11.9 0.2 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) EAP30 PF04157.16 CCC68562.1 - 2.4e-58 197.2 0.0 2.7e-58 197.1 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family PseudoU_synth_1 PF01416.20 CCC68563.1 - 6.7e-30 103.7 0.0 4.6e-27 94.6 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Sulfate_transp PF00916.20 CCC68564.1 - 2.2e-96 322.9 19.1 3e-96 322.5 19.1 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CCC68564.1 - 9e-21 73.7 0.1 7.3e-20 70.7 0.0 2.2 2 0 0 2 2 2 1 STAS domain MFS_MOT1 PF16983.5 CCC68564.1 - 0.00036 20.9 7.9 0.00036 20.9 7.9 3.1 2 1 0 2 2 2 1 Molybdate transporter of MFS superfamily ETF PF01012.21 CCC68565.1 - 9.3e-32 110.4 0.0 1.5e-31 109.7 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 CCC68565.1 - 7.9e-30 102.7 0.1 1.4e-29 102.0 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain EF-hand_5 PF13202.6 CCC68565.1 - 0.041 13.4 0.0 2.1 8.0 0.0 2.5 2 0 0 2 2 2 0 EF hand DUF4047 PF13256.6 CCC68566.1 - 0.0046 17.1 0.1 0.0046 17.1 0.1 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4047) PolyA_pol PF01743.20 CCC68567.1 - 8.7e-32 110.2 0.0 1.8e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 CCC68567.1 - 7.1e-07 28.9 0.0 2.5e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.6 CCC68567.1 - 0.012 15.6 0.4 0.012 15.6 0.4 2.6 3 1 0 3 3 3 0 tRNA nucleotidyltransferase domain 2 putative ArenaCapSnatch PF17296.2 CCC68567.1 - 0.049 13.1 0.7 0.19 11.1 0.1 2.1 2 0 0 2 2 2 0 Arenavirus cap snatching domain SEP PF08059.13 CCC68567.1 - 0.12 12.9 0.2 0.7 10.5 0.0 2.3 3 0 0 3 3 3 0 SEP domain JmjC PF02373.22 CCC68568.1 - 1.1e-40 138.6 4.2 1.7e-40 138.0 0.7 2.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 CCC68568.1 - 3.9e-13 49.1 2.6 3.9e-13 49.1 2.6 2.5 2 0 0 2 2 2 1 jmjN domain zf-H2C2_2 PF13465.6 CCC68568.1 - 1.4e-06 28.5 7.2 1.4e-06 28.5 7.2 2.6 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.26 CCC68568.1 - 3.9e-05 23.9 15.4 0.0093 16.4 2.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC68568.1 - 0.0011 19.7 14.9 0.2 12.6 2.4 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger Zn-ribbon_8 PF09723.10 CCC68568.1 - 0.0028 17.7 2.8 0.008 16.3 2.8 1.8 1 0 0 1 1 1 1 Zinc ribbon domain CNDH2_C PF16858.5 CCC68568.1 - 0.0041 17.0 1.5 0.0041 17.0 1.5 1.7 2 0 0 2 2 2 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term zf-C2H2_6 PF13912.6 CCC68568.1 - 0.014 15.4 4.7 0.014 15.4 4.7 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-UDP PF14569.6 CCC68568.1 - 0.04 14.0 0.6 0.083 13.0 0.6 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C2H2_11 PF16622.5 CCC68568.1 - 0.15 11.9 9.1 0.026 14.3 3.6 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_C2H2_ZHX PF18387.1 CCC68568.1 - 0.19 11.4 3.4 0.23 11.1 2.1 1.8 1 1 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zinc_ribbon_5 PF13719.6 CCC68568.1 - 0.33 10.7 1.3 0.76 9.6 1.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CCC68568.1 - 1.1 9.2 3.6 4.8 7.2 3.2 2.2 1 1 0 1 1 1 0 SprT-like zinc ribbon domain zf-C2H2_jaz PF12171.8 CCC68568.1 - 2.3 8.6 10.6 1.2 9.5 3.1 2.7 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.15 CCC68568.1 - 2.3 8.3 5.7 13 5.9 1.0 2.8 2 0 0 2 2 2 0 BED zinc finger zf-UBP PF02148.19 CCC68568.1 - 3.8 7.9 6.2 2.4e+02 2.2 6.2 2.4 1 1 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein ADK PF00406.22 CCC68569.1 - 4e-43 147.1 0.0 4.9e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CCC68569.1 - 2.8e-19 69.9 0.0 4.3e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 CCC68569.1 - 6e-14 51.7 0.0 1.1e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 CCC68569.1 - 0.0001 22.4 0.0 0.00031 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCC68569.1 - 0.0004 20.9 0.0 0.00073 20.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CCC68569.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI 6PF2K PF01591.18 CCC68569.1 - 0.053 12.8 0.3 9.9 5.4 0.0 2.6 3 0 0 3 3 3 0 6-phosphofructo-2-kinase DEAD_2 PF06733.15 CCC68570.1 - 4.1e-56 189.4 2.6 7.7e-56 188.5 2.6 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CCC68570.1 - 1.4e-44 152.3 0.0 3.9e-44 150.8 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain HBB PF06777.11 CCC68570.1 - 9.2e-44 149.4 1.9 4.5e-39 134.1 0.4 2.7 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 CCC68570.1 - 0.00077 19.5 0.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CCC68570.1 - 0.01 15.6 0.0 2.3 8.0 0.0 2.6 2 0 0 2 2 2 0 DEAD/DEAH box helicase Sec63 PF02889.16 CCC68571.1 - 5.9e-143 474.6 4.4 6.8e-78 261.4 0.1 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 CCC68571.1 - 3.3e-46 157.2 0.1 7.3e-28 97.5 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 CCC68571.1 - 2.1e-25 89.7 0.4 1.5e-13 51.1 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCC68571.1 - 1.9e-10 41.1 1.0 1.9e-08 34.7 0.0 4.6 5 1 0 5 5 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CCC68571.1 - 1.2e-06 28.8 0.3 0.058 13.7 0.1 3.3 2 1 0 2 2 2 2 AAA domain AAA PF00004.29 CCC68571.1 - 2.9e-05 24.5 0.2 0.024 15.0 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCC68571.1 - 0.0044 17.4 0.1 0.22 11.9 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 CCC68571.1 - 0.014 14.9 0.0 6.5 6.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 CCC68571.1 - 0.09 11.8 0.0 9.7 5.1 0.0 2.6 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.17 CCC68571.1 - 0.13 12.0 0.0 16 5.2 0.0 3.4 3 0 0 3 3 3 0 IstB-like ATP binding protein CENP-B_dimeris PF09026.10 CCC68571.1 - 1.5 9.3 6.7 4.4 7.8 6.7 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Rad17 PF03215.15 CCC68572.1 - 2.6e-42 144.8 0.0 5.7e-42 143.7 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 CCC68572.1 - 3.6e-05 24.2 0.1 0.00011 22.6 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_11 PF13086.6 CCC68572.1 - 0.015 15.1 1.1 0.64 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CCC68572.1 - 0.022 15.1 0.2 0.39 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 CCC68572.1 - 0.023 14.6 0.0 0.094 12.6 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase AAA_5 PF07728.14 CCC68572.1 - 0.073 13.1 0.0 0.18 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 CCC68572.1 - 0.096 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA PF00004.29 CCC68572.1 - 0.13 12.6 0.0 0.37 11.2 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 CCC68572.1 - 0.14 11.9 0.0 0.4 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glutaredoxin PF00462.24 CCC68573.1 - 8.8e-17 61.1 0.0 6.4e-16 58.3 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 CCC68573.1 - 3.9e-13 49.3 0.0 1.2e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 CCC68573.1 - 2e-05 24.5 0.1 9.5e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.6 CCC68573.1 - 0.0001 22.5 1.6 0.0011 19.2 0.1 3.0 2 2 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.6 CCC68573.1 - 0.0078 16.7 0.1 1.8 9.1 0.0 3.3 2 2 1 3 3 3 1 Thioredoxin-like domain SH3BGR PF04908.15 CCC68573.1 - 0.0088 16.2 0.0 0.021 15.0 0.0 1.6 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein DIM1 PF02966.16 CCC68573.1 - 0.0093 15.8 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 1 Mitosis protein DIM1 HyaE PF07449.11 CCC68573.1 - 0.024 14.6 0.1 0.17 11.9 0.1 2.4 3 1 1 4 4 4 0 Hydrogenase-1 expression protein HyaE Methyltransf_25 PF13649.6 CCC68574.1 - 1.2e-13 51.6 0.1 3.2e-13 50.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC68574.1 - 2.2e-11 44.4 0.0 6.2e-11 42.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC68574.1 - 2.6e-11 44.0 0.0 4.5e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC68574.1 - 2.7e-11 43.5 0.0 3.9e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCC68574.1 - 2.3e-07 30.8 0.0 3.4e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCC68574.1 - 2.5e-06 27.0 0.0 4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 CCC68574.1 - 0.0047 16.3 0.0 0.0074 15.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CCC68574.1 - 0.0063 16.1 0.0 0.017 14.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 CCC68574.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.6 CCC68574.1 - 0.013 15.5 0.0 0.02 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 CCC68574.1 - 0.081 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 CCC68574.1 - 0.1 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AAA_12 PF13087.6 CCC68575.1 - 5.2e-61 205.8 0.1 1.3e-60 204.4 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CCC68575.1 - 3.4e-35 122.1 0.6 3.2e-19 69.8 0.1 4.1 2 2 1 3 3 2 2 AAA domain AAA_19 PF13245.6 CCC68575.1 - 9.7e-13 48.7 0.2 3e-12 47.1 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 CCC68575.1 - 8.3e-11 42.0 0.0 1.1e-09 38.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CCC68575.1 - 2.2e-07 30.9 2.4 0.2 11.4 0.0 4.4 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CCC68575.1 - 3.2e-05 24.0 0.0 3.2e-05 24.0 0.0 3.7 4 1 0 4 4 3 1 Type III restriction enzyme, res subunit UPF1_Zn_bind PF09416.10 CCC68575.1 - 0.0013 18.7 1.9 0.0013 18.7 1.9 2.3 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) ATPase_2 PF01637.18 CCC68575.1 - 0.003 17.5 0.1 0.013 15.4 0.1 2.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea PhoH PF02562.16 CCC68575.1 - 0.0032 16.9 0.1 0.014 14.9 0.1 2.1 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 CCC68575.1 - 0.005 17.1 0.0 0.019 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CCC68575.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.29 CCC68575.1 - 0.0078 16.6 0.0 0.031 14.7 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCC68575.1 - 0.016 15.6 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 CCC68575.1 - 0.038 13.5 0.0 0.13 11.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing dynein motor region 14-3-3 PF00244.20 CCC68576.1 - 5.4e-106 353.1 4.0 8.2e-106 352.5 4.0 1.3 1 0 0 1 1 1 1 14-3-3 protein FlaF PF07309.11 CCC68576.1 - 0.004 17.2 0.8 0.0098 15.9 0.8 1.6 1 0 0 1 1 1 1 Flagellar protein FlaF SF3A2 PF16835.5 CCC68576.1 - 0.063 13.6 0.1 0.18 12.2 0.1 1.8 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) E1_dh PF00676.20 CCC68577.1 - 5.2e-122 406.5 0.0 6.4e-122 406.2 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 CCC68577.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase ABC_trans_N PF14510.6 CCC68577.1 - 0.06 14.0 0.0 0.17 12.5 0.0 1.8 2 0 0 2 2 2 0 ABC-transporter N-terminal KRTAP7 PF15034.6 CCC68577.1 - 0.34 11.9 5.0 1.5 9.8 0.1 3.2 2 2 0 2 2 2 0 KRTAP type 7 family Rad51 PF08423.11 CCC68578.1 - 8.8e-102 339.7 0.0 9.9e-102 339.6 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 CCC68578.1 - 4.3e-08 33.0 0.0 5.7e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 CCC68578.1 - 1e-05 25.1 0.0 1.4e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein AAA_22 PF13401.6 CCC68578.1 - 0.006 16.9 0.1 0.012 15.9 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 CCC68578.1 - 0.039 13.7 0.0 0.11 12.2 0.0 1.7 1 1 1 2 2 2 0 AAA domain DUF2205 PF10224.9 CCC68580.1 - 9.7e-08 31.9 4.0 1e-07 31.8 4.0 1.1 1 0 0 1 1 1 1 Short coiled-coil protein CRM1_C PF08767.11 CCC68580.1 - 0.027 13.7 0.1 0.031 13.5 0.1 1.0 1 0 0 1 1 1 0 CRM1 C terminal EMP70 PF02990.16 CCC68581.1 - 3.3e-193 643.1 15.9 4.9e-193 642.5 15.9 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 Rax2 PF12768.7 CCC68582.1 - 3.4e-55 186.8 1.5 3.4e-55 186.8 1.5 5.7 4 2 2 7 7 7 2 Cortical protein marker for cell polarity DUF5122 PF17164.4 CCC68582.1 - 0.012 15.9 2.4 4.1 7.8 0.1 4.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5122) beta-propeller ecTbetaR2 PF08917.10 CCC68582.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Transforming growth factor beta receptor 2 ectodomain Actin PF00022.19 CCC68583.1 - 6.8e-51 173.1 0.0 8.2e-50 169.6 0.0 2.0 1 1 0 1 1 1 1 Actin HlyD_2 PF12700.7 CCC68583.1 - 0.03 13.0 2.1 0.21 10.3 0.3 2.4 3 0 0 3 3 3 0 HlyD family secretion protein SMC_N PF02463.19 CCC68584.1 - 6e-69 231.8 46.7 5e-68 228.8 46.7 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCC68584.1 - 4.7e-25 88.2 0.0 1.9e-24 86.2 0.0 2.1 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 CCC68584.1 - 1.1e-10 41.8 3.7 6.3e-06 26.2 0.0 4.7 4 1 0 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCC68584.1 - 7.2e-05 22.4 0.0 0.00016 21.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CCC68584.1 - 8e-05 22.5 47.7 8e-05 22.5 47.7 4.5 2 2 2 4 4 4 1 AAA ATPase domain ERM PF00769.19 CCC68584.1 - 0.00096 19.0 25.9 0.00096 19.0 25.9 5.1 2 2 2 4 4 4 2 Ezrin/radixin/moesin family DUF745 PF05335.13 CCC68584.1 - 0.0065 16.2 0.7 0.0065 16.2 0.7 7.1 3 2 5 8 8 8 1 Protein of unknown function (DUF745) Snapin_Pallidin PF14712.6 CCC68584.1 - 0.0083 16.5 5.0 0.0083 16.5 5.0 9.1 5 2 3 9 9 9 2 Snapin/Pallidin HSBP1 PF06825.12 CCC68584.1 - 3.4 7.6 11.0 0.68 9.8 0.7 4.2 3 1 1 4 4 4 0 Heat shock factor binding protein 1 Jacalin PF01419.17 CCC68584.1 - 3.5 7.6 9.3 7.3 6.5 0.0 3.7 3 0 0 3 3 3 0 Jacalin-like lectin domain Aminotran_1_2 PF00155.21 CCC68586.1 - 3.5e-39 135.0 0.0 5.1e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 CCC68586.1 - 0.033 13.5 0.0 0.054 12.8 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DnaJ_C PF01556.18 CCC68587.1 - 4.6e-32 111.2 0.2 7.5e-32 110.5 0.2 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCC68587.1 - 1.7e-25 88.9 2.1 4e-25 87.7 2.1 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCC68587.1 - 2.6e-10 40.5 13.4 6.6e-10 39.2 13.4 1.8 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.6 CCC68587.1 - 0.013 15.9 3.1 0.013 15.9 3.1 2.4 2 1 0 2 2 2 0 Cytochrome c3 Anti-TRAP PF15777.5 CCC68587.1 - 0.13 12.3 12.7 0.26 11.3 3.3 2.7 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein GEP5 PF17053.5 CCC68588.1 - 3.1e-44 151.5 1.0 4.6e-44 150.9 1.0 1.3 1 0 0 1 1 1 1 Genetic interactor of prohibitin 5 Sulfate_transp PF00916.20 CCC68589.1 - 2.8e-125 418.0 8.3 3.5e-125 417.7 8.3 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CCC68589.1 - 4.2e-06 26.4 0.0 8.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 CCC68589.1 - 0.0069 16.7 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 CCC68589.1 - 0.027 14.9 1.1 0.027 14.9 1.1 2.5 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily Nyv1_N PF09426.10 CCC68590.1 - 2.9e-60 202.2 0.6 4.1e-60 201.8 0.1 1.4 2 0 0 2 2 2 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.21 CCC68590.1 - 5.4e-27 93.4 3.8 8.3e-27 92.8 3.8 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF2391 PF09622.10 CCC68590.1 - 0.047 13.0 0.2 0.069 12.5 0.2 1.2 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) DUF4621 PF15414.6 CCC68591.1 - 0.05 12.5 1.4 0.057 12.3 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4621) PHD PF00628.29 CCC68592.1 - 1.1 9.2 7.8 0.054 13.4 1.8 1.9 2 0 0 2 2 2 0 PHD-finger Pkinase PF00069.25 CCC68593.1 - 1.2e-69 234.7 1.5 2.5e-67 227.0 1.5 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68593.1 - 2.1e-40 138.7 0.5 1.3e-38 132.8 0.5 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 CCC68593.1 - 7.7e-18 64.0 0.0 1.7e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 CCC68593.1 - 3.9e-06 26.4 0.4 2.5e-05 23.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CCC68593.1 - 0.00024 20.5 0.2 0.00047 19.6 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 CCC68593.1 - 0.0046 15.9 3.0 0.017 14.1 0.1 2.4 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 CCC68593.1 - 0.0074 16.2 0.0 0.16 11.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCC68593.1 - 0.013 14.3 0.0 0.013 14.3 0.0 2.7 3 0 0 3 3 3 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 CCC68593.1 - 0.091 12.3 0.2 0.38 10.2 0.1 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL F-box-like PF12937.7 CCC68594.1 - 4.7e-06 26.4 0.1 8.7e-06 25.5 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CCC68594.1 - 5.9e-05 22.8 0.8 0.00012 21.8 0.8 1.4 1 0 0 1 1 1 1 F-box domain MIT PF04212.18 CCC68594.1 - 0.0089 16.1 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Fungal_trans PF04082.18 CCC68595.1 - 8e-36 123.4 3.3 8e-36 123.4 3.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC68595.1 - 4.9e-09 36.2 8.2 8.3e-09 35.4 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_1 PF00561.20 CCC68596.1 - 4e-20 72.5 0.0 1.2e-18 67.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCC68596.1 - 5.2e-13 50.1 0.0 7.7e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCC68596.1 - 2.9e-09 36.6 0.0 1.9e-06 27.4 0.0 2.9 2 1 0 2 2 2 2 Serine aminopeptidase, S33 DUF915 PF06028.11 CCC68596.1 - 4.1e-08 32.9 1.5 2.3e-06 27.1 1.5 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 CCC68596.1 - 6e-05 23.3 0.0 0.033 14.3 0.0 2.3 1 1 1 2 2 2 2 Thioesterase domain Ndr PF03096.14 CCC68596.1 - 0.00095 17.9 0.0 0.049 12.3 0.0 2.4 1 1 0 2 2 2 1 Ndr family Esterase PF00756.20 CCC68596.1 - 0.0013 18.4 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Chlorophyllase2 PF12740.7 CCC68596.1 - 0.0044 16.0 0.0 0.011 14.7 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme LIDHydrolase PF10230.9 CCC68596.1 - 0.0077 15.8 0.0 0.011 15.3 0.0 1.6 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase BAAT_C PF08840.11 CCC68596.1 - 0.014 15.3 0.0 4 7.3 0.0 2.5 3 0 0 3 3 3 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 CCC68596.1 - 0.019 14.7 0.2 1.9 8.2 0.0 3.0 3 0 0 3 3 3 0 Alpha/beta hydrolase family PGAP1 PF07819.13 CCC68596.1 - 0.02 14.6 0.1 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase PF07224.11 CCC68596.1 - 0.089 11.8 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase BTV_NS2 PF04514.12 CCC68596.1 - 0.091 11.6 0.1 0.24 10.2 0.0 1.6 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Ser_hydrolase PF06821.13 CCC68596.1 - 0.093 12.6 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase MIOX PF05153.15 CCC68596.1 - 0.095 12.3 3.8 0.059 12.9 1.2 1.9 2 1 0 2 2 2 0 Myo-inositol oxygenase Atg31 PF09795.9 CCC68597.1 - 0.012 15.7 0.5 0.18 11.8 0.4 2.5 1 1 0 1 1 1 0 Autophagy-related protein 31 Prp18 PF02840.15 CCC68597.1 - 0.019 15.0 0.1 0.035 14.1 0.1 1.4 1 0 0 1 1 1 0 Prp18 domain MFA1_2 PF17317.2 CCC68598.1 - 5.3e-24 83.7 0.5 5.6e-24 83.6 0.5 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 LOR PF04525.12 CCC68598.1 - 0.12 12.0 0.0 0.12 12.0 0.0 1.0 1 0 0 1 1 1 0 LURP-one-related SKIP_SNW PF02731.15 CCC68599.1 - 6.4e-45 152.7 8.0 1.1e-44 151.9 8.0 1.3 1 0 0 1 1 1 1 SKIP/SNW domain Pinin_SDK_memA PF04696.13 CCC68599.1 - 0.098 12.7 10.5 0.88 9.6 3.8 2.5 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region SurA_N_2 PF13623.6 CCC68599.1 - 0.21 11.5 3.3 0.18 11.7 0.9 2.0 2 0 0 2 2 2 0 SurA N-terminal domain DUF2681 PF10883.8 CCC68599.1 - 0.39 11.2 4.3 0.99 9.9 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) RTX PF02382.15 CCC68600.1 - 0.12 12.1 4.4 0.14 11.9 4.4 1.1 1 0 0 1 1 1 0 N-terminal domain in RTX protein AAA_23 PF13476.6 CCC68600.1 - 0.24 11.9 7.8 0.27 11.7 7.8 1.1 1 0 0 1 1 1 0 AAA domain RNA_pol_3_Rpc31 PF11705.8 CCC68600.1 - 1.3 9.2 13.3 1.7 8.9 13.3 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 EPSP_synthase PF00275.20 CCC68601.1 - 2.4e-137 458.0 0.0 4.2e-137 457.2 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.20 CCC68601.1 - 4.6e-100 334.1 0.0 6.9e-100 333.5 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.15 CCC68601.1 - 7.9e-59 199.7 0.0 1.6e-58 198.7 0.0 1.6 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.22 CCC68601.1 - 3.4e-37 128.0 0.0 1.9e-35 122.3 0.0 2.8 3 0 0 3 3 3 1 Shikimate kinase Shikimate_dh_N PF08501.11 CCC68601.1 - 4.9e-21 74.8 0.0 1.7e-20 73.1 0.0 2.0 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 CCC68601.1 - 2.9e-10 39.7 0.1 6.3e-10 38.6 0.1 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 CCC68601.1 - 1e-07 32.1 0.0 2.8e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.6 CCC68601.1 - 1.2e-06 28.5 0.0 2.9e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_33 PF13671.6 CCC68601.1 - 0.01 16.0 0.0 0.026 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CCC68601.1 - 0.13 12.3 0.0 0.43 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 CCC68602.1 - 4.7e-11 42.5 0.0 2.6e-10 40.1 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCC68602.1 - 0.0018 17.9 0.0 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase CH PF00307.31 CCC68603.1 - 3.9e-82 271.6 0.1 7.7e-21 74.3 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.6 CCC68603.1 - 3.8e-06 27.3 0.8 2.6e-05 24.6 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain pair CAMSAP_CH PF11971.8 CCC68603.1 - 4.5e-06 26.4 0.0 0.041 13.7 0.0 4.2 4 0 0 4 4 4 1 CAMSAP CH domain CH_2 PF06294.11 CCC68603.1 - 9.4e-05 22.5 0.1 0.32 11.1 0.0 3.7 4 1 0 4 4 4 2 CH-like domain in sperm protein ANAPC9 PF12856.7 CCC68604.1 - 7.3e-12 45.5 0.2 1.3e-11 44.7 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 9 Blt1 PF12754.7 CCC68604.1 - 0.024 14.9 0.5 0.053 13.8 0.1 1.7 2 0 0 2 2 2 0 Blt1 N-terminal domain CDC45 PF02724.14 CCC68605.1 - 3e-212 706.4 0.1 3.5e-212 706.2 0.1 1.0 1 0 0 1 1 1 1 CDC45-like protein Drc1-Sld2 PF11719.8 CCC68605.1 - 0.0065 16.1 0.6 0.008 15.8 0.6 1.2 1 0 0 1 1 1 1 DNA replication and checkpoint protein Sigma70_ner PF04546.13 CCC68605.1 - 0.35 10.7 8.6 0.22 11.4 6.5 1.7 2 0 0 2 2 2 0 Sigma-70, non-essential region Nop53 PF07767.11 CCC68605.1 - 0.41 10.0 12.8 0.58 9.5 12.8 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 CCC68605.1 - 1.5 6.9 12.4 2.1 6.5 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.10 CCC68605.1 - 3.9 6.8 10.5 5.8 6.2 10.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RNA_pol_3_Rpc31 PF11705.8 CCC68605.1 - 5.3 7.2 17.3 9.2 6.5 17.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Sporozoite_P67 PF05642.11 CCC68605.1 - 7 4.6 5.5 11 4.0 5.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.11 CCC68605.1 - 7.6 4.9 8.0 13 4.2 8.0 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Sdh5 PF03937.16 CCC68606.1 - 1.4e-26 92.3 0.6 2.1e-26 91.7 0.6 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase PCI PF01399.27 CCC68607.1 - 2.1e-09 37.8 0.3 8.4e-09 35.9 0.0 2.2 2 0 0 2 2 2 1 PCI domain Smg4_UPF3 PF03467.15 CCC68608.1 - 7.2e-30 104.3 1.2 7.2e-30 104.3 1.2 3.6 2 1 2 4 4 4 1 Smg-4/UPF3 family DUF4778 PF16008.5 CCC68608.1 - 0.82 9.7 16.6 0.28 11.2 3.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) LSM PF01423.22 CCC68609.1 - 1.6e-22 78.9 0.0 2.9e-22 78.1 0.0 1.4 1 1 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCC68609.1 - 0.0024 17.9 0.1 0.0058 16.8 0.1 1.8 1 1 0 1 1 1 1 Ataxin 2 SM domain ABC_tran PF00005.27 CCC68614.1 - 3.5e-52 176.6 0.5 5.6e-25 88.4 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.24 CCC68614.1 - 6.4e-40 136.8 30.5 1.5e-23 83.3 11.2 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.6 CCC68614.1 - 7.1e-13 49.0 2.5 0.001 18.9 0.1 4.4 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCC68614.1 - 2.3e-09 37.1 5.6 8.1e-05 22.2 0.3 3.6 3 1 0 3 3 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 CCC68614.1 - 9.7e-09 35.3 3.8 0.00059 19.8 0.1 3.2 2 1 1 3 3 3 2 RsgA GTPase AAA_18 PF13238.6 CCC68614.1 - 2.6e-07 31.2 0.4 0.042 14.4 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CCC68614.1 - 6e-07 30.0 0.0 0.052 13.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CCC68614.1 - 4.6e-06 26.3 5.6 0.0086 15.8 0.1 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 CCC68614.1 - 7.3e-06 26.3 0.6 0.3 11.3 0.1 3.5 2 1 1 3 3 3 2 AAA domain AAA_23 PF13476.6 CCC68614.1 - 8.5e-06 26.4 1.1 0.051 14.1 0.2 3.3 3 1 0 3 3 2 2 AAA domain T2SSE PF00437.20 CCC68614.1 - 1.4e-05 24.3 0.3 0.072 12.1 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.12 CCC68614.1 - 3.5e-05 23.8 0.0 0.017 15.1 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_25 PF13481.6 CCC68614.1 - 8e-05 22.3 0.0 0.026 14.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CCC68614.1 - 8.2e-05 22.7 0.2 0.16 12.1 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.6 CCC68614.1 - 0.00011 22.4 0.0 0.09 13.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCC68614.1 - 0.00035 20.3 1.1 0.7 9.6 0.3 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CCC68614.1 - 0.00045 20.6 0.1 1.1 9.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_17 PF13207.6 CCC68614.1 - 0.00082 19.8 0.0 2.3 8.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CCC68614.1 - 0.0013 18.5 1.0 0.74 9.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 CCC68614.1 - 0.0021 18.0 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CCC68614.1 - 0.0022 18.0 0.0 1.5 8.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 CCC68614.1 - 0.0025 17.6 0.1 0.24 11.1 0.0 2.9 3 0 0 3 3 3 1 Cytidylate kinase NB-ARC PF00931.22 CCC68614.1 - 0.0026 17.0 0.8 2.3 7.3 0.2 2.6 2 0 0 2 2 2 2 NB-ARC domain Rad17 PF03215.15 CCC68614.1 - 0.0032 17.4 0.4 2.6 7.9 0.0 2.8 3 0 0 3 3 2 1 Rad17 P-loop domain KAP_NTPase PF07693.14 CCC68614.1 - 0.0045 16.3 0.0 0.94 8.6 0.0 2.4 2 0 0 2 2 2 1 KAP family P-loop domain cobW PF02492.19 CCC68614.1 - 0.0054 16.3 0.8 1.8 8.2 0.3 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CCC68614.1 - 0.0061 16.5 0.4 5.3 6.9 0.1 3.0 3 0 0 3 3 3 0 NTPase ATPase PF06745.13 CCC68614.1 - 0.01 15.2 0.4 1.2 8.4 0.0 3.2 3 0 0 3 3 3 0 KaiC AAA PF00004.29 CCC68614.1 - 0.012 16.0 0.0 12 6.4 0.0 3.4 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CCC68614.1 - 0.013 15.7 0.1 8.3 6.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 CCC68614.1 - 0.017 14.5 1.3 0.77 9.1 0.2 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family Pox_A32 PF04665.12 CCC68614.1 - 0.018 14.5 2.7 0.15 11.5 0.2 2.8 3 0 0 3 3 3 0 Poxvirus A32 protein AAA_19 PF13245.6 CCC68614.1 - 0.022 15.1 0.3 0.45 10.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 CCC68614.1 - 0.026 14.7 0.2 13 6.1 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 CCC68614.1 - 0.036 14.2 5.4 2.3 8.3 0.9 3.7 3 0 0 3 3 3 0 Helicase HerA, central domain PRK PF00485.18 CCC68614.1 - 0.037 13.8 0.9 3.8 7.2 0.0 2.7 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family Adeno_IVa2 PF02456.15 CCC68614.1 - 0.051 12.4 0.9 0.07 11.9 0.1 1.5 2 0 0 2 2 2 0 Adenovirus IVa2 protein AAA_5 PF07728.14 CCC68614.1 - 0.064 13.3 0.3 2.7 8.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 CCC68614.1 - 0.068 12.0 0.1 1.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class dNK PF01712.19 CCC68614.1 - 0.071 13.0 0.3 16 5.3 0.0 2.7 3 0 0 3 3 2 0 Deoxynucleoside kinase Zeta_toxin PF06414.12 CCC68614.1 - 0.12 11.6 0.2 7.1 5.9 0.3 2.3 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 CCC68614.1 - 0.13 12.3 3.7 18 5.3 0.3 3.8 4 0 0 4 4 4 0 Dynamin family Septin PF00735.18 CCC68614.1 - 0.2 10.9 1.5 4.6 6.4 0.0 2.8 3 0 0 3 3 3 0 Septin MobB PF03205.14 CCC68614.1 - 0.22 11.4 0.8 3 7.7 0.2 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.17 CCC68614.1 - 0.36 10.6 5.8 5.7 6.6 0.1 3.0 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein Brix PF04427.18 CCC68615.1 - 8.6e-41 140.2 0.2 1.2e-40 139.7 0.2 1.2 1 0 0 1 1 1 1 Brix domain Nucleopor_Nup85 PF07575.13 CCC68615.1 - 0.061 11.9 0.1 0.076 11.6 0.1 1.1 1 0 0 1 1 1 0 Nup85 Nucleoporin SUV3_C PF12513.8 CCC68615.1 - 1.9 8.5 3.8 10 6.1 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial degradasome RNA helicase subunit C terminal ATP19 PF11022.8 CCC68616.1 - 4.3e-19 68.7 0.1 4.5e-19 68.6 0.1 1.0 1 0 0 1 1 1 1 ATP synthase subunit K CRIM PF16978.5 CCC68617.1 - 1.3e-36 125.8 2.1 1.1e-35 122.8 0.8 2.7 2 0 0 2 2 2 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain SIN1_PH PF16979.5 CCC68617.1 - 4.7e-31 107.3 0.6 4.7e-31 107.3 0.6 3.0 3 0 0 3 3 3 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology RBD PF02196.15 CCC68617.1 - 0.004 17.2 0.0 0.015 15.3 0.0 2.0 1 0 0 1 1 1 1 Raf-like Ras-binding domain RNase_T PF00929.24 CCC68618.1 - 1.1e-21 78.1 0.1 4.4e-20 72.9 0.0 2.2 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 CCC68618.1 - 0.0035 17.1 0.0 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease DUF3340 PF11818.8 CCC68618.1 - 0.09 12.9 3.9 0.18 11.9 3.9 1.5 1 0 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) RasGAP PF00616.19 CCC68619.1 - 2.1e-23 83.1 1.6 2.3e-15 56.9 0.5 3.4 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase POLO_box PF00659.18 CCC68619.1 - 0.021 15.0 0.1 1.7 8.9 0.1 3.2 2 0 0 2 2 2 0 POLO box duplicated region MitMem_reg PF13012.6 CCC68619.1 - 0.093 13.2 0.4 14 6.1 0.0 4.2 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function LAGLIDADG_2 PF03161.13 CCC68619.1 - 0.31 11.1 3.8 1.1 9.2 2.5 2.7 1 1 0 1 1 1 0 LAGLIDADG DNA endonuclease family Myb_DNA-bind_7 PF15963.5 CCC68620.1 - 0.094 12.6 1.9 0.19 11.6 1.5 1.8 1 1 0 1 1 1 0 Myb DNA-binding like ATG19_autophagy PF12744.7 CCC68621.1 - 7.4e-24 84.3 6.3 1e-23 83.8 6.0 1.3 1 1 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding RSN1_7TM PF02714.15 CCC68622.1 - 6.2e-86 288.1 22.8 1.2e-85 287.1 22.8 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CCC68622.1 - 2.8e-41 140.9 3.4 2.8e-41 140.9 3.4 2.8 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 CCC68622.1 - 5.4e-26 90.6 0.1 1.1e-25 89.6 0.1 1.6 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 CCC68622.1 - 3.6e-24 85.9 0.1 6.3e-24 85.2 0.1 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF2236 PF09995.9 CCC68622.1 - 0.03 14.5 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) Orf78 PF06024.12 CCC68622.1 - 2.7 8.3 5.1 0.85 10.0 0.2 2.8 3 0 0 3 3 3 0 Orf78 (ac78) CENP-S PF15630.6 CCC68624.1 - 2.4e-27 95.1 0.0 3e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 CCC68624.1 - 1.3e-09 38.1 0.0 1.9e-09 37.6 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCC68624.1 - 0.0035 17.7 0.1 0.0047 17.3 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 CCC68624.1 - 0.0038 17.2 0.1 0.0062 16.5 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated DUF3337 PF11816.8 CCC68625.1 - 7.9e-31 107.2 0.4 1.8e-30 106.1 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 CCC68625.1 - 0.0085 16.9 6.3 3 8.9 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat RAWUL PF16207.5 CCC68625.1 - 0.039 14.6 0.1 0.1 13.3 0.1 1.8 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like E1-E2_ATPase PF00122.20 CCC68626.1 - 1.4e-48 164.8 4.1 1.4e-48 164.8 4.1 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CCC68626.1 - 9.9e-18 65.2 1.2 1.9e-17 64.3 0.1 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 CCC68626.1 - 6.5e-11 41.8 0.0 1.5e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 CCC68626.1 - 0.0011 19.0 0.0 0.0022 18.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 CCC68626.1 - 0.0025 17.6 0.1 0.0058 16.4 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Phage_fiber_C PF06820.12 CCC68626.1 - 0.04 14.3 0.1 0.16 12.3 0.1 2.0 1 0 0 1 1 1 0 Putative prophage tail fibre C-terminus DUF2614 PF11023.8 CCC68626.1 - 8.1 6.6 9.8 0.28 11.3 2.4 2.5 2 0 0 2 2 2 0 Zinc-ribbon containing domain Kelch_4 PF13418.6 CCC68628.1 - 3.5e-15 55.7 9.8 0.00021 21.2 0.0 5.4 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 CCC68628.1 - 9.6e-14 51.1 4.9 1.2e-09 38.1 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 CCC68628.1 - 5.8e-13 48.2 1.6 0.0027 17.3 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 CCC68628.1 - 1.1e-08 35.2 0.8 0.023 15.0 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CCC68628.1 - 9.6e-08 31.7 0.4 0.00083 19.2 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.6 CCC68628.1 - 1.9e-06 27.8 0.1 0.0023 17.9 0.0 3.7 3 0 0 3 3 3 1 Kelch motif Ureide_permease PF07168.11 CCC68628.1 - 0.016 14.0 0.1 0.053 12.3 0.1 1.8 1 0 0 1 1 1 0 Ureide permease D-ser_dehydrat PF14031.6 CCC68629.1 - 1.3e-20 73.8 0.0 6.6e-20 71.6 0.0 2.1 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 CCC68629.1 - 6.8e-09 35.7 0.0 1.1e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HEAT_EZ PF13513.6 CCC68630.1 - 3.8e-32 110.3 12.7 7.4e-05 23.2 0.0 15.1 11 4 6 17 17 17 7 HEAT-like repeat HEAT_2 PF13646.6 CCC68630.1 - 3.3e-28 97.9 10.2 0.00053 20.3 0.2 10.6 7 2 5 12 12 11 7 HEAT repeats HEAT PF02985.22 CCC68630.1 - 4.7e-28 94.8 11.0 0.0062 16.7 0.0 18.2 22 0 0 22 22 21 5 HEAT repeat Gcn1_N PF12074.8 CCC68630.1 - 1.6e-21 77.1 3.4 2.4e-14 53.4 0.4 4.2 3 0 0 3 3 3 2 Generalcontrol nonderepressible 1 (Gcn1) N-terminal CLASP_N PF12348.8 CCC68630.1 - 7.7e-17 61.6 0.0 0.00028 20.5 0.0 7.6 6 2 2 8 8 8 3 CLASP N terminal Cnd1 PF12717.7 CCC68630.1 - 3.6e-14 53.1 12.5 0.029 14.4 0.0 11.7 9 3 5 14 14 14 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CCC68630.1 - 1.1e-10 41.9 5.6 3.2 8.4 0.0 10.5 10 5 2 13 13 11 3 Vacuolar 14 Fab1-binding region ParcG PF10274.9 CCC68630.1 - 0.2 11.8 4.9 9.5 6.3 0.0 5.5 6 1 0 6 6 6 0 Parkin co-regulated protein RIX1 PF08167.12 CCC68630.1 - 0.62 9.8 6.8 76 3.0 0.2 5.8 5 0 0 5 5 5 0 rRNA processing/ribosome biogenesis MCR_alpha_N PF02745.15 CCC68630.1 - 1 8.6 2.6 2.5 7.4 1.8 1.9 2 0 0 2 2 2 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain DUF3385 PF11865.8 CCC68630.1 - 2.7 7.9 12.7 41 4.0 0.0 7.6 7 1 1 8 8 8 0 Domain of unknown function (DUF3385) U3snoRNP10 PF12397.8 CCC68630.1 - 5.5 7.4 10.5 53 4.2 0.0 6.5 8 0 0 8 8 7 0 U3 small nucleolar RNA-associated protein 10 Hist_deacetyl PF00850.19 CCC68632.1 - 1.7e-83 280.7 0.0 2.1e-83 280.4 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MT-A70 PF05063.14 CCC68633.1 - 7.8e-58 195.2 0.2 1.7e-57 194.1 0.2 1.6 1 0 0 1 1 1 1 MT-A70 Glyco_hydro_30 PF02055.16 CCC68633.1 - 0.069 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 TIM-barrel domain Chordopox_A13L PF05961.11 CCC68633.1 - 0.33 11.2 2.7 44 4.4 0.6 3.2 3 0 0 3 3 3 0 Chordopoxvirus A13L protein COX6A PF02046.15 CCC68634.1 - 1.3e-38 131.9 0.5 1.4e-38 131.8 0.5 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa UcrQ PF02939.16 CCC68634.1 - 0.02 14.8 0.6 0.28 11.2 0.1 2.2 1 1 1 2 2 2 0 UcrQ family WD40 PF00400.32 CCC68635.1 - 1.7e-14 53.9 1.3 0.017 16.0 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC68635.1 - 0.00024 21.3 0.2 26 5.2 0.0 5.0 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1150 PF06620.11 CCC68635.1 - 0.14 12.3 0.0 3.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1150) COX5B PF01215.19 CCC68636.1 - 5.7e-63 210.4 0.0 6.9e-63 210.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Transp_cyt_pur PF02133.15 CCC68638.1 - 3.7e-15 55.6 28.7 3.7e-15 55.6 28.7 2.0 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin Nramp PF01566.18 CCC68638.1 - 0.2 10.6 22.1 0.083 11.8 11.3 2.6 3 0 0 3 3 3 0 Natural resistance-associated macrophage protein Pox_EPC_I2-L1 PF12575.8 CCC68638.1 - 0.78 10.0 4.5 6.7 7.0 0.8 3.2 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 AcetylCoA_hydro PF02550.15 CCC68639.1 - 7e-73 244.8 0.1 2e-72 243.4 0.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.6 CCC68639.1 - 1.3e-40 138.9 0.0 2.1e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.12 CCC68639.1 - 0.036 13.0 0.1 0.074 11.9 0.1 1.4 1 1 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.23 CCC68639.1 - 0.056 12.8 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Coenzyme A transferase Pkinase PF00069.25 CCC68640.1 - 1.5e-67 227.8 0.0 1.9e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68640.1 - 1.4e-31 109.8 0.0 1.8e-31 109.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCC68640.1 - 0.0027 16.7 1.9 0.009 15.0 1.9 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CCC68640.1 - 0.053 12.9 0.1 0.081 12.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Sortilin-Vps10 PF15902.5 CCC68641.1 - 3.5e-213 708.3 9.6 5e-145 483.7 5.3 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 CCC68641.1 - 2.4e-72 242.8 16.7 7.8e-39 133.7 2.0 2.5 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 CCC68641.1 - 5.1e-16 56.0 48.3 0.36 11.0 0.3 13.3 12 0 0 12 12 12 9 BNR/Asp-box repeat CHB_HEX_C PF03174.13 CCC68641.1 - 0.0023 17.9 3.3 3.4 7.7 0.0 4.3 5 0 0 5 5 5 2 Chitobiase/beta-hexosaminidase C-terminal domain PSII_BNR PF14870.6 CCC68641.1 - 0.0076 15.5 7.4 1.5 8.0 0.0 4.9 6 1 0 6 6 6 2 Photosynthesis system II assembly factor YCF48 zf-GRF PF06839.12 CCC68643.1 - 3.1e-09 36.8 0.7 6.4e-09 35.8 0.7 1.6 1 0 0 1 1 1 1 GRF zinc finger Exo_endo_phos PF03372.23 CCC68643.1 - 9.5e-08 31.8 0.0 5.6e-07 29.3 0.0 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 CCC68643.1 - 1.3e-06 28.3 0.5 0.022 14.6 0.0 3.2 3 0 0 3 3 3 2 Endonuclease-reverse transcriptase Rft-1 PF04506.13 CCC68644.1 - 2.4e-222 739.2 39.1 2.8e-222 739.0 39.1 1.0 1 0 0 1 1 1 1 Rft protein MatE PF01554.18 CCC68644.1 - 0.001 18.7 2.3 0.001 18.7 2.3 3.6 4 1 0 4 4 4 1 MatE Insulin_TMD PF17870.1 CCC68644.1 - 2.1 8.5 5.6 5.9 7.0 0.1 3.6 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment CBFD_NFYB_HMF PF00808.23 CCC68645.1 - 7.2e-26 90.3 0.0 9.6e-26 89.9 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 CCC68645.1 - 7e-05 23.2 0.2 0.00011 22.6 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 CCC68645.1 - 0.0058 16.7 0.0 0.0073 16.4 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID_20kDa PF03847.13 CCC68645.1 - 0.015 15.7 0.2 0.18 12.4 0.1 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.13 CCC68645.1 - 0.038 14.0 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated LepB_N PF18640.1 CCC68645.1 - 0.077 12.6 0.1 0.14 11.8 0.1 1.3 1 1 0 1 1 1 0 LepB N-terminal domain Lon_C PF05362.13 CCC68646.1 - 1.1e-65 221.1 0.0 3e-65 219.6 0.0 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 CCC68646.1 - 4.1e-33 115.0 6.9 4.1e-33 115.0 6.9 2.6 2 1 0 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 CCC68646.1 - 3.8e-23 82.4 0.0 1e-22 80.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 CCC68646.1 - 1.9e-07 31.4 0.0 7.1e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 CCC68646.1 - 1.5e-06 28.3 0.0 3.9e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 CCC68646.1 - 8.9e-06 25.6 0.0 2.3e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_22 PF13401.6 CCC68646.1 - 8.4e-05 22.9 0.1 0.0016 18.7 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.11 CCC68646.1 - 0.00061 18.8 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain IstB_IS21 PF01695.17 CCC68646.1 - 0.00061 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.6 CCC68646.1 - 0.0012 19.2 0.0 0.0074 16.7 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 CCC68646.1 - 0.0013 18.5 0.0 0.0094 15.7 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CCC68646.1 - 0.0021 18.6 0.7 0.016 15.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 CCC68646.1 - 0.0031 17.5 0.0 0.011 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 CCC68646.1 - 0.0035 17.7 0.0 0.086 13.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_24 PF13479.6 CCC68646.1 - 0.032 14.0 0.2 1.4 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 CCC68646.1 - 0.032 14.4 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 Shikimate kinase RsgA_GTPase PF03193.16 CCC68646.1 - 0.047 13.6 0.0 0.21 11.5 0.0 2.1 1 0 0 1 1 1 0 RsgA GTPase NTPase_1 PF03266.15 CCC68646.1 - 0.053 13.4 0.5 1.2 9.0 0.1 3.0 2 1 1 3 3 3 0 NTPase TsaE PF02367.17 CCC68646.1 - 0.061 13.3 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 CCC68646.1 - 0.12 11.8 0.3 0.43 10.1 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Cytidylate_kin PF02224.18 CCC68646.1 - 0.73 9.5 4.2 3.8 7.2 0.0 3.0 3 0 0 3 3 3 0 Cytidylate kinase DNTTIP1_dimer PF18192.1 CCC68646.1 - 1 9.7 4.3 60 4.1 1.1 4.1 3 1 1 4 4 4 0 DNTTIP1 dimerisation domain ABC_tran PF00005.27 CCC68646.1 - 2.6 8.6 5.0 1.4 9.4 0.1 2.9 3 1 0 3 3 2 0 ABC transporter MCM PF00493.23 CCC68647.1 - 3.6e-102 340.2 0.1 5.6e-102 339.6 0.1 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCC68647.1 - 1.8e-36 124.7 0.0 3.4e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCC68647.1 - 2.2e-26 92.1 0.2 5e-26 90.9 0.2 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 CCC68647.1 - 1.2e-23 84.1 31.0 1.2e-23 84.1 31.0 3.8 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 CCC68647.1 - 4.3e-12 46.5 0.0 1.5e-11 44.8 0.0 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCC68647.1 - 2.6e-09 36.8 0.0 2.5e-07 30.3 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCC68647.1 - 2e-07 31.1 0.0 5.2e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CCC68647.1 - 0.00056 19.8 0.0 0.0031 17.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCC68647.1 - 0.002 17.8 0.1 0.012 15.3 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain SelR PF01641.18 CCC68647.1 - 0.0023 18.0 0.1 0.084 13.0 0.1 2.4 2 0 0 2 2 2 1 SelR domain AAA PF00004.29 CCC68647.1 - 0.019 15.4 0.0 0.055 13.9 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 CCC68647.1 - 0.048 13.4 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain Yippee-Mis18 PF03226.14 CCC68647.1 - 0.18 12.0 0.1 0.38 11.0 0.1 1.5 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Methyltr_RsmB-F PF01189.17 CCC68648.1 - 1.9e-43 148.4 0.3 3.2e-42 144.5 0.3 2.3 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 CCC68648.1 - 0.0009 19.4 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase HhH-GPD PF00730.25 CCC68651.1 - 7.9e-12 45.6 0.0 1.2e-11 45.0 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein COX15-CtaA PF02628.15 CCC68652.1 - 1.3e-114 382.6 7.9 1.6e-114 382.4 7.9 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein FXMR_C2 PF16098.5 CCC68652.1 - 0.0042 17.6 0.0 0.0081 16.6 0.0 1.4 1 0 0 1 1 1 1 Fragile X-related mental retardation protein C-terminal region 2 Abhydrolase_9_N PF15420.6 CCC68652.1 - 0.76 9.7 6.4 0.076 13.0 0.5 2.2 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus DUF747 PF05346.11 CCC68653.1 - 9.8e-83 278.2 24.8 1.7e-82 277.5 24.8 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family RPAP2_Rtr1 PF04181.13 CCC68654.1 - 1.1e-16 60.8 1.1 1.7e-16 60.3 0.3 1.7 2 0 0 2 2 2 1 Rtr1/RPAP2 family Ribosomal_S13_N PF08069.12 CCC68655.1 - 7.1e-29 99.6 0.1 1.2e-28 98.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 CCC68655.1 - 1.9e-14 53.6 0.6 3.2e-14 52.9 0.2 1.5 2 0 0 2 2 2 1 Ribosomal protein S15 GDI PF00996.18 CCC68656.1 - 1.1e-224 745.9 0.1 1.2e-224 745.7 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.6 CCC68656.1 - 0.0013 18.9 0.0 0.0032 17.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Copper-fist PF00649.18 CCC68657.1 - 9.8e-22 76.2 0.6 2e-21 75.2 0.6 1.6 1 0 0 1 1 1 1 Copper fist DNA binding domain Zn_clus PF00172.18 CCC68658.1 - 7.7e-09 35.5 25.9 0.00038 20.5 1.8 4.3 4 0 0 4 4 4 4 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2 PF00096.26 CCC68659.1 - 3.8e-08 33.4 11.5 0.00037 20.8 0.7 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC68659.1 - 1.8e-05 25.2 8.0 0.018 15.9 0.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCC68659.1 - 0.0001 22.5 7.5 0.0017 18.7 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain FOXP-CC PF16159.5 CCC68659.1 - 0.031 14.9 0.2 0.031 14.9 0.2 2.8 3 0 0 3 3 3 0 FOXP coiled-coil domain zf-BED PF02892.15 CCC68659.1 - 0.06 13.4 0.8 0.06 13.4 0.8 2.5 2 0 0 2 2 2 0 BED zinc finger zf-met PF12874.7 CCC68659.1 - 0.25 11.8 8.2 0.43 11.0 0.4 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FYVE PF01363.21 CCC68659.1 - 0.34 11.1 2.5 0.89 9.7 2.3 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-H2C2_5 PF13909.6 CCC68659.1 - 0.64 9.8 8.6 6.6 6.6 0.3 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain rve PF00665.26 CCC68660.1 - 2.4e-12 47.1 0.0 3.1e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Integrase_H2C2 PF17921.1 CCC68660.1 - 6.7e-09 35.7 0.4 1.2e-08 34.9 0.2 1.6 2 0 0 2 2 2 1 Integrase zinc binding domain DASH_Dad4 PF08650.10 CCC68660.1 - 0.18 11.8 0.0 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 RT_RNaseH PF17917.1 CCC68661.1 - 1.5e-12 47.7 0.7 2.3e-12 47.1 0.7 1.2 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CCC68661.1 - 0.01 15.9 0.1 0.025 14.6 0.1 1.6 1 0 0 1 1 1 0 RNase H-like domain found in reverse transcriptase T5orf172 PF10544.9 CCC68662.1 - 7.7e-08 32.8 0.1 9e-06 26.2 0.1 2.2 1 1 0 1 1 1 1 T5orf172 domain MUG113 PF13455.6 CCC68662.1 - 1.9e-06 28.4 0.0 2.9e-05 24.7 0.0 2.2 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 EF-hand_6 PF13405.6 CCC68662.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain adh_short PF00106.25 CCC68663.1 - 0.029 13.8 0.0 0.039 13.4 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase LUC7 PF03194.15 CCC68664.1 - 2.4e-56 191.2 12.2 2.9e-56 191.0 12.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus KLRAQ PF10205.9 CCC68664.1 - 0.052 13.8 5.7 0.15 12.4 5.7 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Seryl_tRNA_N PF02403.22 CCC68664.1 - 0.57 10.4 7.9 3 8.1 2.9 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2418 PF10332.9 CCC68665.1 - 3.7e-23 81.9 4.1 1e-22 80.5 4.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) UPF0542 PF15086.6 CCC68665.1 - 0.044 13.7 0.9 0.14 12.1 0.9 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Prenyltrans PF00432.21 CCC68666.1 - 6.9e-43 144.1 7.1 8.3e-12 44.6 0.3 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat UBX PF00789.20 CCC68667.1 - 2.7e-15 56.3 0.0 5.4e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 UBX domain SRP14 PF02290.15 CCC68668.1 - 4.8e-24 84.6 0.1 4.8e-24 84.6 0.1 1.7 1 1 1 2 2 2 1 Signal recognition particle 14kD protein PMT PF02366.18 CCC68669.1 - 2.6e-66 223.7 19.1 2.6e-66 223.7 19.1 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCC68669.1 - 7.7e-54 182.3 13.1 7.7e-54 182.3 13.1 1.9 2 0 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCC68669.1 - 9.3e-40 136.5 0.0 9.3e-40 136.5 0.0 2.0 2 0 0 2 2 2 1 MIR domain Merozoite_SPAM PF07133.11 CCC68669.1 - 0.0064 16.5 21.0 0.012 15.7 21.0 1.3 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) Fibrinogen_BP PF08017.11 CCC68669.1 - 0.0093 14.4 6.6 0.014 13.9 6.6 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein Lin-8 PF03353.15 CCC68669.1 - 1.5 8.3 16.2 2.4 7.7 16.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PMT PF02366.18 CCC68670.1 - 5e-88 294.8 19.3 5e-88 294.8 19.3 1.7 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCC68670.1 - 2e-59 200.6 15.7 2e-59 200.6 15.7 2.0 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCC68670.1 - 9e-44 149.5 0.5 1.4e-43 148.9 0.5 1.3 1 0 0 1 1 1 1 MIR domain PMT_2 PF13231.6 CCC68670.1 - 0.00019 21.7 18.6 0.00019 21.7 18.6 3.0 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase RPN6_N PF18055.1 CCC68671.1 - 3.9e-39 133.6 3.9 3.9e-39 133.6 3.9 2.8 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 CCC68671.1 - 4.8e-19 68.8 1.0 1.8e-18 67.0 0.0 2.5 2 1 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 CCC68671.1 - 1.3e-09 37.6 0.1 4.4e-09 35.9 0.1 2.0 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 CCC68671.1 - 3.4e-06 27.3 3.0 0.011 16.0 0.3 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCC68671.1 - 0.00017 22.2 0.4 0.57 10.9 0.2 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat DDRGK PF09756.9 CCC68671.1 - 0.00045 19.8 0.1 0.00045 19.8 0.1 2.1 2 1 0 2 2 2 1 DDRGK domain TPR_15 PF13429.6 CCC68671.1 - 0.003 16.8 1.6 0.0063 15.8 1.6 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CCC68671.1 - 0.17 11.2 2.5 0.14 11.5 0.3 1.8 2 0 0 2 2 2 0 MalT-like TPR region HNOB PF07700.15 CCC68671.1 - 0.43 10.5 5.3 0.95 9.4 0.3 3.0 2 1 1 3 3 3 0 Haem-NO-binding DUF4606 PF15379.6 CCC68671.1 - 4 7.7 6.8 1.5 9.1 0.9 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4606) TPR_2 PF07719.17 CCC68671.1 - 4.1 7.8 13.3 9.7 6.6 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-met PF12874.7 CCC68672.1 - 3.1e-07 30.6 0.8 5.9e-07 29.7 0.8 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCC68672.1 - 1.4e-05 25.3 1.5 3.2e-05 24.1 1.5 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding KGK PF08872.10 CCC68672.1 - 0.0018 18.8 0.4 0.0018 18.8 0.4 2.4 1 1 1 2 2 2 1 KGK domain zf-DBF PF07535.12 CCC68672.1 - 0.0054 16.8 1.2 0.014 15.5 1.2 1.7 1 0 0 1 1 1 1 DBF zinc finger MAAL_C PF07476.11 CCC68672.1 - 0.012 14.8 0.1 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus zf-C2H2_4 PF13894.6 CCC68672.1 - 0.025 15.4 0.4 0.066 14.1 0.4 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CCC68672.1 - 0.037 14.5 1.5 0.084 13.4 1.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type P2_Phage_GpR PF06891.11 CCC68672.1 - 0.051 13.6 0.1 0.11 12.6 0.1 1.5 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) BST2 PF16716.5 CCC68673.1 - 0.0066 17.0 10.6 0.0066 17.0 10.6 3.8 3 1 1 4 4 4 1 Bone marrow stromal antigen 2 DUF848 PF05852.11 CCC68673.1 - 0.0092 16.1 8.1 0.0092 16.1 8.1 2.6 2 1 0 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) FlxA PF14282.6 CCC68673.1 - 0.013 15.5 15.1 0.013 15.5 15.1 3.7 4 1 0 4 4 4 0 FlxA-like protein LPP PF04728.13 CCC68673.1 - 7.8 7.0 12.6 6.4 7.2 3.2 3.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper ArsA_ATPase PF02374.15 CCC68674.1 - 1.2e-115 385.9 0.1 1.4e-115 385.7 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 CCC68674.1 - 3.3e-10 40.1 0.9 6.2e-09 36.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 CCC68674.1 - 6e-10 39.3 0.0 1.2e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.18 CCC68674.1 - 0.00095 18.7 0.1 0.0017 17.9 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ParA PF10609.9 CCC68674.1 - 0.0011 18.5 1.3 0.0085 15.6 0.6 2.5 2 1 1 3 3 3 1 NUBPL iron-transfer P-loop NTPase AAA_25 PF13481.6 CCC68674.1 - 0.017 14.7 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CCC68674.1 - 0.02 14.5 0.0 0.68 9.5 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PhoH PF02562.16 CCC68674.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.22 CCC68674.1 - 0.11 11.7 0.0 0.2 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.12 CCC68674.1 - 0.15 12.0 0.2 0.95 9.4 0.0 2.2 2 0 0 2 2 2 0 NACHT domain Pkinase PF00069.25 CCC68675.1 - 8.5e-70 235.1 0.0 1.2e-69 234.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68675.1 - 2.6e-35 122.0 0.0 3.4e-35 121.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CCC68675.1 - 4.1e-17 62.3 1.2 1.1e-16 60.9 1.2 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 CCC68675.1 - 9.5e-07 29.1 0.0 3.7e-06 27.2 0.0 2.0 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 CCC68675.1 - 8.6e-06 24.8 0.0 1.7e-05 23.8 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CCC68675.1 - 0.0031 16.9 0.2 0.0053 16.1 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CCC68675.1 - 0.016 14.8 1.3 0.07 12.7 0.3 2.1 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DNA_pol_B PF00136.21 CCC68676.1 - 1.2e-144 482.5 2.1 1.7e-144 482.0 2.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CCC68676.1 - 8.2e-87 291.5 0.0 2.2e-86 290.1 0.0 1.8 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CCC68676.1 - 3e-17 62.9 4.5 5.9e-17 61.9 4.5 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 CCC68676.1 - 5.4e-06 25.5 0.4 0.00054 18.9 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 CCC68676.1 - 0.0067 16.1 0.2 0.014 15.1 0.0 1.6 2 0 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 CCC68676.1 - 0.012 15.6 0.5 0.084 12.9 0.5 2.3 1 1 0 1 1 1 0 RNase_H superfamily UDPGP PF01704.18 CCC68677.1 - 3.8e-46 157.6 0.0 5.2e-46 157.1 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4142 PF13628.6 CCC68677.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4142) DUF4034 PF13226.6 CCC68678.1 - 0.47 9.8 5.3 0.088 12.1 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4034) DUF4551 PF15087.6 CCC68678.1 - 3.3 6.4 9.6 3.8 6.2 9.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) TFIIA PF03153.13 CCC68678.1 - 3.6 7.5 17.0 4.5 7.2 17.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 CCC68678.1 - 4.1 6.1 8.6 5.1 5.8 8.6 1.0 1 0 0 1 1 1 0 Presenilin CPSF100_C PF13299.6 CCC68678.1 - 7.8 6.7 6.3 6.1 7.0 4.7 1.5 1 1 1 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal LisH PF08513.11 CCC68679.1 - 0.00037 20.4 3.2 0.0007 19.5 3.2 1.5 1 0 0 1 1 1 1 LisH HAUS6_N PF14661.6 CCC68679.1 - 0.021 14.4 13.1 0.048 13.2 13.1 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus CLN3 PF02487.17 CCC68679.1 - 4.2 6.3 10.3 12 4.8 10.3 1.7 1 0 0 1 1 1 0 CLN3 protein Peptidase_M22 PF00814.25 CCC68680.1 - 3e-70 237.0 0.0 3.7e-70 236.7 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 CCC68680.1 - 0.022 14.4 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus BcrAD_BadFG PF01869.20 CCC68680.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Nse4_C PF08743.10 CCC68681.1 - 6.7e-30 103.2 1.5 6.7e-30 103.2 1.5 2.6 3 0 0 3 3 3 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 CCC68681.1 - 1.7e-10 40.8 0.0 4e-10 39.7 0.0 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF1178 PF06676.11 CCC68681.1 - 0.089 13.2 0.0 0.089 13.2 0.0 2.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1178) Homeodomain PF00046.29 CCC68682.1 - 7.2e-17 61.0 1.4 1.2e-16 60.2 1.4 1.4 1 0 0 1 1 1 1 Homeodomain L_protein_N PF15518.6 CCC68682.1 - 0.035 13.9 0.8 0.094 12.6 0.8 1.8 1 0 0 1 1 1 0 L protein N-terminus Homeobox_KN PF05920.11 CCC68682.1 - 0.06 13.3 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 Homeobox KN domain Auxin_canalis PF05703.11 CCC68682.1 - 0.81 9.6 3.3 2.3 8.1 3.3 1.8 1 0 0 1 1 1 0 Auxin canalisation TPR_2 PF07719.17 CCC68683.1 - 0.0087 16.1 1.7 30 5.1 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat Pkinase PF00069.25 CCC68684.1 - 1.6e-73 247.4 0.0 1.8e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68684.1 - 1.4e-31 109.7 0.0 2.8e-31 108.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC68684.1 - 0.00017 21.0 0.1 0.00057 19.3 0.0 1.9 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 CCC68684.1 - 0.0044 17.0 0.2 0.006 16.5 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF676 PF05057.14 CCC68685.1 - 7e-55 185.9 0.6 1.3e-54 185.0 0.6 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.7 CCC68685.1 - 0.00062 19.6 0.1 0.0015 18.3 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.15 CCC68685.1 - 0.0017 17.6 0.0 0.0039 16.4 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Palm_thioest PF02089.15 CCC68685.1 - 0.0076 16.1 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 CCC68685.1 - 0.024 14.5 0.1 0.054 13.4 0.1 1.6 1 0 0 1 1 1 0 Lipase (class 3) SH3_1 PF00018.28 CCC68686.1 - 2.2e-05 24.0 0.2 0.00013 21.5 0.0 2.4 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CCC68686.1 - 0.00021 21.1 0.1 0.00042 20.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCC68686.1 - 0.00096 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Nup84_Nup100 PF04121.13 CCC68687.1 - 1.2e-189 632.0 12.0 1.4e-189 631.8 12.0 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF1340 PF07067.11 CCC68687.1 - 0.045 13.1 0.1 0.086 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) ACDC PF14733.6 CCC68687.1 - 0.14 12.5 1.1 1.6 9.1 0.0 3.0 3 0 0 3 3 3 0 AP2-coincident C-terminal Iwr1 PF08574.10 CCC68688.1 - 1.4e-15 58.0 17.7 1.4e-15 58.0 17.7 4.3 3 2 0 3 3 3 1 Transcription factor Iwr1 Ribosomal_L17 PF01196.19 CCC68688.1 - 0.1 13.5 0.1 0.64 11.0 0.0 2.2 3 0 0 3 3 3 0 Ribosomal protein L17 adh_short PF00106.25 CCC68689.1 - 4.9e-41 140.4 0.0 5.9e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCC68689.1 - 2.1e-25 89.6 0.0 2.9e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCC68689.1 - 4.4e-13 49.5 0.2 1.9e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.21 CCC68689.1 - 0.00049 19.6 0.0 0.00068 19.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCC68689.1 - 0.014 14.4 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CCC68689.1 - 0.23 11.3 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Actin PF00022.19 CCC68690.1 - 2.3e-95 319.6 0.0 4.5e-94 315.4 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CCC68690.1 - 0.00018 20.4 0.0 0.28 9.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein ADH_zinc_N_2 PF13602.6 CCC68691.1 - 8e-13 49.6 0.0 2.5e-12 48.0 0.0 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CCC68691.1 - 4.9e-07 29.8 0.0 9.2e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCC68691.1 - 0.00011 22.0 0.0 0.00026 20.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 CCC68691.1 - 0.064 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Baculo_gp41 PF04700.12 CCC68691.1 - 0.067 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region PX PF00787.24 CCC68692.1 - 1.5e-22 79.7 0.2 2.1e-21 76.0 0.0 2.4 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 CCC68692.1 - 3.1e-06 26.9 3.4 3.1e-06 26.9 3.4 2.4 1 1 0 2 2 2 1 Vps5 C terminal like CCDC-167 PF15188.6 CCC68692.1 - 0.088 13.2 4.6 0.15 12.4 0.4 2.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 eIF3_N PF09440.10 CCC68692.1 - 1.5 9.2 9.0 0.33 11.4 0.1 3.1 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain SpoU_methylase PF00588.19 CCC68693.1 - 2.6e-25 89.2 0.0 5.5e-25 88.2 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family Sigma70_r1_1 PF03979.14 CCC68693.1 - 0.025 14.6 0.6 0.075 13.1 0.6 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 TIM PF00121.18 CCC68693.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Triosephosphate isomerase HIP1_clath_bdg PF16515.5 CCC68694.1 - 0.012 16.2 4.2 0.061 13.9 4.1 1.9 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 zf-C4H2 PF10146.9 CCC68694.1 - 0.012 15.9 6.2 0.091 13.1 4.1 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein BLOC1_2 PF10046.9 CCC68694.1 - 0.023 15.0 4.5 0.042 14.1 0.7 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Exonuc_VII_L PF02601.15 CCC68694.1 - 0.028 14.0 1.6 0.033 13.8 1.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.9 CCC68694.1 - 0.052 13.6 6.4 0.063 13.3 6.4 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 CCC68694.1 - 0.075 11.9 8.0 0.2 10.5 7.8 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein SNARE PF05739.19 CCC68694.1 - 0.087 12.8 0.1 0.24 11.4 0.0 1.7 2 0 0 2 2 2 0 SNARE domain DUF16 PF01519.16 CCC68694.1 - 0.089 13.3 4.8 0.14 12.7 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF3922 PF13059.6 CCC68694.1 - 0.092 13.2 0.6 0.18 12.2 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3992) TBCA PF02970.16 CCC68694.1 - 0.3 11.4 6.2 0.39 11.1 4.6 1.8 1 1 1 2 2 2 0 Tubulin binding cofactor A DegQ PF08181.11 CCC68694.1 - 0.99 9.5 9.6 2.2 8.5 0.2 2.6 3 0 0 3 3 3 0 DegQ (SacQ) family TMPIT PF07851.13 CCC68694.1 - 1.2 8.4 4.4 4 6.6 4.4 1.8 1 1 0 1 1 1 0 TMPIT-like protein Mito_carr PF00153.27 CCC68695.1 - 2.2e-47 158.9 6.7 6.1e-20 70.9 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Frataxin_Cyay PF01491.16 CCC68696.1 - 1e-35 122.1 0.0 1.3e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain RTBV_P46 PF06216.11 CCC68696.1 - 0.075 11.9 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein UCH PF00443.29 CCC68697.1 - 1.7e-48 165.3 0.1 2.4e-48 164.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCC68697.1 - 5.7e-07 29.4 1.7 3.1e-06 27.0 1.7 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NRIP1_repr_1 PF15687.5 CCC68697.1 - 0.099 12.3 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Nuclear receptor-interacting protein 1 repression 1 ORC_WH_C PF18137.1 CCC68697.1 - 1.3 9.1 9.0 0.64 10.1 0.1 2.5 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal RRM_1 PF00076.22 CCC68698.1 - 1.9e-55 184.6 0.2 9.6e-19 67.0 0.2 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCC68698.1 - 2e-09 37.1 0.8 1.4e-05 24.7 0.2 2.9 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCC68698.1 - 2.8e-09 36.7 0.0 0.00055 19.7 0.0 3.1 3 0 0 3 3 3 2 Occluded RNA-recognition motif DbpA PF03880.15 CCC68698.1 - 0.00045 20.2 0.1 1.9 8.5 0.0 2.8 3 0 0 3 3 3 2 DbpA RNA binding domain Nup35_RRM_2 PF14605.6 CCC68698.1 - 0.00078 19.4 0.3 0.061 13.3 0.0 2.9 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CCC68698.1 - 0.0012 19.0 0.2 0.28 11.3 0.1 3.7 3 1 1 4 4 4 1 RNA recognition motif DUF1987 PF09345.10 CCC68698.1 - 0.018 14.7 0.8 1.2 8.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) PHM7_cyt PF14703.6 CCC68698.1 - 1.8 8.8 6.8 1.7 8.8 0.0 3.1 4 0 0 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter DFP PF04127.15 CCC68699.1 - 1.7e-15 57.3 0.0 3.6e-06 26.9 0.0 3.3 3 1 0 3 3 3 2 DNA / pantothenate metabolism flavoprotein Sds3 PF08598.11 CCC68700.1 - 3.2e-77 259.4 6.5 3.7e-77 259.2 6.5 1.0 1 0 0 1 1 1 1 Sds3-like Tim44 PF04280.15 CCC68700.1 - 0.011 15.8 0.6 0.041 14.0 0.1 2.0 2 0 0 2 2 2 0 Tim44-like domain Glyco_transf_15 PF01793.16 CCC68701.1 - 2e-85 286.9 17.7 8.3e-55 186.3 8.9 2.1 1 1 0 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase CENP-T_C PF15511.6 CCC68702.1 - 1.9e-09 37.6 0.1 2.2e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCC68702.1 - 2.1e-05 24.9 0.1 2.5e-05 24.7 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CCC68702.1 - 3e-05 24.1 0.1 4.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CCC68702.1 - 3.6e-05 24.0 0.1 6.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CCC68702.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CCC68702.1 - 0.0029 17.7 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CCC68702.1 - 0.0067 16.4 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 CCC68702.1 - 0.043 14.3 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 CCC68703.1 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CCC68703.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CCC68703.1 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CCC68703.1 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CCC68703.1 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CCC68703.1 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Aim19 PF10315.9 CCC68704.1 - 9.8e-41 138.7 2.7 1.2e-40 138.4 2.7 1.1 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 Aa_trans PF01490.18 CCC68705.1 - 1.2e-113 379.9 17.4 1.4e-113 379.7 17.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ICE2 PF08426.10 CCC68706.1 - 1.3e-158 528.4 32.5 1.5e-158 528.2 32.5 1.0 1 0 0 1 1 1 1 ICE2 UTP25 PF06862.12 CCC68707.1 - 2.9e-202 672.6 7.7 3.9e-202 672.2 7.7 1.2 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 CCC68707.1 - 0.00041 20.2 0.1 0.99 9.1 0.1 2.8 2 1 0 2 2 2 2 DEAD/DEAH box helicase MTS_N PF08468.11 CCC68707.1 - 0.02 14.9 0.0 0.5 10.4 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal MRP-S25 PF13741.6 CCC68708.1 - 1.6e-94 315.8 7.3 1.8e-94 315.6 7.3 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.9 CCC68708.1 - 9e-06 26.0 2.8 0.002 18.4 0.1 2.8 1 1 0 2 2 2 2 Mitochondrial ribosomal protein S23 Iso_dh PF00180.20 CCC68709.1 - 6.2e-113 377.5 0.1 7.6e-113 377.2 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.25 CCC68710.1 - 2.7e-38 131.9 0.0 4.2e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68710.1 - 1.1e-29 103.5 0.0 1.6e-29 103.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC68710.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCC68710.1 - 0.034 14.1 0.0 0.28 11.1 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cytochrom_C1 PF02167.15 CCC68710.1 - 0.15 11.7 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C1 family Pkinase_fungal PF17667.1 CCC68710.1 - 0.53 9.0 0.0 0.53 9.0 0.0 2.8 2 1 0 2 2 2 0 Fungal protein kinase DUF2431 PF10354.9 CCC68711.1 - 1.9e-53 181.2 0.0 2.9e-53 180.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) CLTH PF10607.9 CCC68712.1 - 3e-26 92.1 7.4 3e-26 92.1 7.4 2.8 2 2 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Nudix_N PF12535.8 CCC68712.1 - 0.027 14.1 0.0 0.068 12.8 0.0 1.6 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Zn-C2H2_12 PF18112.1 CCC68712.1 - 0.72 10.4 2.3 1.4 9.4 0.1 2.5 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain OmpH PF03938.14 CCC68712.1 - 4.2 7.7 10.9 2.2 8.6 8.5 1.7 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Iso_dh PF00180.20 CCC68713.1 - 8e-75 252.1 0.5 9.1e-75 252.0 0.5 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Complex1_LYR_2 PF13233.6 CCC68714.1 - 9.9e-12 45.4 7.1 5.6e-11 43.0 7.1 2.0 1 1 0 1 1 1 1 Complex1_LYR-like XLF PF09302.11 CCC68714.1 - 0.48 10.6 7.8 2.2 8.4 0.2 3.0 2 1 1 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component Com_YlbF PF06133.11 CCC68714.1 - 2.9 8.5 6.9 39 4.9 6.2 2.4 1 1 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA Diphthamide_syn PF01866.17 CCC68716.1 - 1.8e-113 379.0 0.0 2.2e-113 378.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SHQ1 PF04925.15 CCC68717.1 - 3e-65 219.0 1.5 4.5e-65 218.5 1.5 1.3 1 0 0 1 1 1 1 SHQ1 protein DUF2202 PF09968.9 CCC68717.1 - 0.053 13.4 0.5 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein domain (DUF2202) PH PF00169.29 CCC68718.1 - 2e-12 47.6 0.6 4.9e-12 46.3 0.6 1.7 1 0 0 1 1 1 1 PH domain RTT107_BRCT_5 PF16770.5 CCC68718.1 - 0.026 14.4 0.0 0.13 12.1 0.0 2.3 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Roughex PF06020.11 CCC68718.1 - 0.37 9.8 5.8 0.68 9.0 5.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Mob1_phocein PF03637.17 CCC68719.1 - 5.3e-67 225.0 0.0 7.2e-67 224.6 0.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family 6PF2K PF01591.18 CCC68720.1 - 3.1e-83 278.5 0.4 5.4e-83 277.7 0.4 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CCC68720.1 - 3.8e-32 111.5 0.0 1.3e-26 93.5 0.0 2.6 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CCC68720.1 - 2.8e-06 27.6 0.0 7.8e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CCC68720.1 - 0.0091 15.5 0.0 0.019 14.4 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 APS_kinase PF01583.20 CCC68720.1 - 0.0092 15.9 0.0 0.025 14.5 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_5 PF07728.14 CCC68720.1 - 0.013 15.5 0.1 2.8 7.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 CCC68720.1 - 0.017 15.7 0.1 0.074 13.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CCC68720.1 - 0.019 15.4 0.0 0.058 13.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF4446 PF14584.6 CCC68720.1 - 2.5 8.1 6.7 3.9 7.5 1.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Metallopep PF12044.8 CCC68721.1 - 1.5e-167 557.6 0.0 2e-167 557.2 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.17 CCC68721.1 - 0.0072 16.3 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_3 PF13582.6 CCC68721.1 - 0.023 15.2 0.1 0.057 13.9 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.6 CCC68721.1 - 0.044 13.9 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M66 PF10462.9 CCC68721.1 - 0.097 11.6 0.2 0.24 10.3 0.0 1.7 2 0 0 2 2 2 0 Peptidase M66 Sec23_trunk PF04811.15 CCC68722.1 - 1.6e-67 227.6 0.1 3.1e-67 226.7 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CCC68722.1 - 8.3e-19 67.3 0.1 2.4e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CCC68722.1 - 3.3e-16 59.8 0.0 7.3e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CCC68722.1 - 4.8e-14 52.1 4.6 1.1e-13 51.0 4.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 CCC68722.1 - 2.8e-05 23.9 0.0 5.6e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat DUF2756 PF10956.8 CCC68722.1 - 0.24 11.9 9.4 0.45 11.0 7.8 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2756) Methyltransf_12 PF08242.12 CCC68723.1 - 0.068 13.9 0.0 0.2 12.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.9 CCC68723.1 - 0.11 12.2 0.0 4.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Lysine methyltransferase COX4 PF02936.14 CCC68724.1 - 9.8e-35 119.6 1.6 1.1e-34 119.4 1.6 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV N1221 PF07923.13 CCC68724.1 - 0.031 13.5 0.2 0.039 13.1 0.2 1.3 1 1 0 1 1 1 0 N1221-like protein DUF1289 PF06945.13 CCC68724.1 - 0.15 11.9 2.5 2.6 7.9 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Ank_2 PF12796.7 CCC68725.1 - 1.1e-34 118.8 7.5 3.6e-17 62.7 0.6 3.4 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCC68725.1 - 1.2e-27 95.6 3.6 1.5e-07 31.6 0.0 4.9 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCC68725.1 - 5.3e-27 93.9 0.0 4.2e-10 40.0 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 CCC68725.1 - 1.7e-22 78.8 3.2 1.6e-06 28.3 0.4 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 CCC68725.1 - 3.9e-21 72.9 0.0 1.4e-06 28.1 0.3 6.2 6 0 0 6 6 6 4 Ankyrin repeat Porin_3 PF01459.22 CCC68726.1 - 1.5e-67 228.0 2.2 1.6e-67 227.8 2.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin NUP214 PF16755.5 CCC68727.1 - 1e-162 541.4 6.2 1e-162 541.4 6.2 2.1 2 0 0 2 2 2 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Aminotran_1_2 PF00155.21 CCC68728.1 - 6.9e-68 229.5 0.0 7.9e-68 229.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 CCC68728.1 - 0.0002 20.3 0.0 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Allinase Aminotran_5 PF00266.19 CCC68728.1 - 0.12 11.3 0.0 0.31 9.9 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V Ras PF00071.22 CCC68730.1 - 1.3e-57 194.0 0.0 1.5e-57 193.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC68730.1 - 1e-22 80.6 0.0 1.7e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC68730.1 - 8.2e-09 35.1 0.0 1.3e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CCC68730.1 - 0.00097 18.4 0.0 0.0011 18.2 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 CCC68730.1 - 0.0017 17.8 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CCC68730.1 - 0.0022 17.4 0.0 0.003 17.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCC68730.1 - 0.0075 16.3 0.0 0.024 14.7 0.0 1.8 1 1 1 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CCC68730.1 - 0.046 14.2 0.1 0.079 13.5 0.1 1.7 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 CCC68730.1 - 0.15 12.4 0.1 0.24 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Myb_DNA-bind_4 PF13837.6 CCC68731.1 - 0.00033 21.0 0.1 0.00083 19.7 0.1 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain Noelin-1 PF12308.8 CCC68731.1 - 0.038 14.0 0.5 0.09 12.8 0.5 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF2275 PF10039.9 CCC68731.1 - 0.097 12.8 0.3 3.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2275) SMYLE_N PF18615.1 CCC68731.1 - 0.42 10.1 3.3 0.71 9.4 0.2 2.1 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain MFS_1 PF07690.16 CCC68732.1 - 6.4e-40 137.2 21.2 5.2e-35 121.0 10.8 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC68732.1 - 4e-10 39.2 23.8 5e-07 28.9 12.7 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter MFS_1_like PF12832.7 CCC68732.1 - 0.0009 18.2 0.0 0.0024 16.8 0.0 1.8 1 1 0 1 1 1 1 MFS_1 like family TRI12 PF06609.13 CCC68732.1 - 0.003 16.1 5.9 0.0045 15.5 5.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Claudin_2 PF13903.6 CCC68732.1 - 0.0067 16.2 11.7 0.034 13.9 0.0 3.3 3 0 0 3 3 3 2 PMP-22/EMP/MP20/Claudin tight junction RasGAP_C PF03836.15 CCC68733.1 - 0.0055 16.8 3.6 0.011 15.8 3.6 1.6 1 1 0 1 1 1 1 RasGAP C-terminus Pox_A6 PF04924.12 CCC68733.1 - 0.066 12.2 0.2 0.087 11.8 0.2 1.1 1 0 0 1 1 1 0 Poxvirus A6 protein SUN PF03856.13 CCC68734.1 - 1.5e-97 325.9 13.8 1.5e-97 325.9 13.8 1.6 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) DUF4667 PF15700.5 CCC68734.1 - 0.016 15.3 10.9 0.025 14.7 10.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) Macoilin PF09726.9 CCC68734.1 - 0.34 9.4 6.0 0.4 9.2 6.0 1.1 1 0 0 1 1 1 0 Macoilin family GREB1 PF15782.5 CCC68734.1 - 0.35 7.9 10.3 0.45 7.6 10.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer CCDC53 PF10152.9 CCC68734.1 - 4.1 7.8 5.8 6.8 7.1 5.8 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex adh_short PF00106.25 CCC68735.1 - 1.8e-47 161.3 0.0 2.5e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCC68735.1 - 1e-28 100.5 0.0 1.3e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCC68735.1 - 1.5e-08 34.7 0.0 2.1e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 CCC68735.1 - 0.00097 18.6 0.0 0.02 14.3 0.0 2.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 CCC68735.1 - 0.002 17.3 0.0 0.003 16.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 CCC68735.1 - 0.0025 17.3 0.0 0.0063 16.0 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Transket_pyr PF02779.24 CCC68736.1 - 8.8e-65 217.7 0.0 1.5e-64 216.9 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 CCC68736.1 - 4.3e-56 190.1 0.0 6.5e-56 189.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 CCC68736.1 - 1.2e-49 167.9 0.0 2e-49 167.2 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 CCC68736.1 - 5.5e-20 70.7 2.8 1.2e-19 69.6 2.8 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus Ribosomal_L6 PF00347.23 CCC68737.1 - 1.1e-29 102.9 12.5 8.5e-15 55.2 5.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 CPT_N PF16484.5 CCC68737.1 - 0.16 12.0 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus SNF2_N PF00176.23 CCC68738.1 - 4.5e-75 252.5 1.1 1.2e-74 251.2 1.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCC68738.1 - 8.5e-22 77.6 1.7 4.1e-19 69.0 0.0 4.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 CCC68738.1 - 1.2e-21 76.5 0.1 4.7e-21 74.6 0.1 2.1 1 0 0 1 1 1 1 Bromodomain HSA PF07529.13 CCC68738.1 - 2.4e-13 50.2 6.3 2.4e-13 50.2 6.3 4.7 4 0 0 4 4 4 1 HSA ResIII PF04851.15 CCC68738.1 - 6.5e-11 42.5 0.0 6.5e-11 42.5 0.0 3.3 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit SnAC PF14619.6 CCC68738.1 - 1.6e-07 31.8 0.5 1.6e-07 31.8 0.5 4.5 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex COMP PF11598.8 CCC68738.1 - 0.45 11.0 3.5 1.4 9.4 0.5 3.4 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein Fungal_trans PF04082.18 CCC68739.1 - 8.2e-38 130.0 0.6 2.1e-37 128.6 0.6 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC68739.1 - 2.2e-11 43.7 11.8 3.6e-11 43.0 11.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Forkhead PF00250.18 CCC68740.1 - 3.9e-33 113.6 0.2 1e-32 112.2 0.2 1.7 2 0 0 2 2 2 1 Forkhead domain FHA PF00498.26 CCC68740.1 - 2.4e-09 37.4 0.0 1.1e-08 35.3 0.0 2.2 2 0 0 2 2 2 1 FHA domain Linker_histone PF00538.19 CCC68740.1 - 0.055 13.8 0.0 0.13 12.6 0.0 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family CSM2 PF16834.5 CCC68741.1 - 3.4e-75 252.1 3.7 3.9e-75 251.9 3.7 1.0 1 0 0 1 1 1 1 Shu complex component Csm2, DNA-binding Ribosomal_L13 PF00572.18 CCC68742.1 - 4.7e-11 43.0 1.2 2.2e-09 37.6 0.2 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 MSP7_C PF12948.7 CCC68742.1 - 0.027 15.1 0.2 0.059 14.0 0.0 1.5 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain Mito_carr PF00153.27 CCC68743.1 - 1.7e-61 204.2 0.8 3.2e-20 71.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Exonuc_VII_L PF02601.15 CCC68745.1 - 0.059 12.9 16.3 0.2 11.2 3.7 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit TPR_16 PF13432.6 CCC68745.1 - 0.61 10.8 5.5 0.92 10.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RICH PF05062.12 CCC68745.1 - 1.1 9.6 0.0 1.1 9.6 0.0 4.4 3 1 1 4 4 4 0 RICH domain Laminin_II PF06009.12 CCC68745.1 - 2.6 8.1 11.6 12 5.9 0.9 3.7 2 1 0 3 3 3 0 Laminin Domain II YtxH PF12732.7 CCC68745.1 - 8.5 7.0 28.4 8.4 7.0 0.0 5.6 3 1 1 4 4 4 0 YtxH-like protein Peptidase_M1 PF01433.20 CCC68746.1 - 2.9e-51 174.1 3.1 1.1e-50 172.2 3.1 1.9 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 CCC68746.1 - 2e-31 109.6 3.3 3.4e-31 108.9 1.7 2.0 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 CCC68746.1 - 6.9e-26 91.5 0.0 1.2e-25 90.8 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain MA3 PF02847.17 CCC68746.1 - 0.1 12.6 0.2 0.57 10.2 0.0 2.3 2 0 0 2 2 2 0 MA3 domain Tropomyosin_1 PF12718.7 CCC68747.1 - 1.6e-49 167.8 40.3 1.8e-49 167.5 40.3 1.0 1 0 0 1 1 1 1 Tropomyosin like Laminin_II PF06009.12 CCC68747.1 - 1.7e-06 28.1 22.5 0.00022 21.3 11.7 2.1 1 1 1 2 2 2 2 Laminin Domain II Tropomyosin PF00261.20 CCC68747.1 - 4.2e-05 23.0 37.3 0.003 17.0 15.8 2.1 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.9 CCC68747.1 - 0.0001 22.5 29.3 0.0025 18.0 16.7 2.1 1 1 1 2 2 2 2 Predicted coiled-coil domain-containing protein CENP-F_leu_zip PF10473.9 CCC68747.1 - 0.00012 22.1 42.9 0.00015 21.8 8.6 2.7 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 CCC68747.1 - 0.00033 20.9 28.1 0.0066 16.7 10.3 3.4 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.6 CCC68747.1 - 0.0013 18.1 36.4 0.02 14.3 22.6 2.8 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding Sec34 PF04136.15 CCC68747.1 - 0.0014 18.5 20.8 0.0017 18.2 14.2 2.1 1 1 1 2 2 2 2 Sec34-like family ZapB PF06005.12 CCC68747.1 - 0.0035 17.8 44.1 0.049 14.1 19.7 3.9 2 1 1 3 3 3 1 Cell division protein ZapB APG6_N PF17675.1 CCC68747.1 - 0.0045 17.5 45.3 0.17 12.4 21.2 2.1 1 1 1 2 2 2 1 Apg6 coiled-coil region MbeD_MobD PF04899.12 CCC68747.1 - 0.0046 17.0 3.1 0.0046 17.0 3.1 2.7 2 1 1 3 3 2 1 MbeD/MobD like FlaC_arch PF05377.11 CCC68747.1 - 0.0046 17.3 28.2 1.8 9.0 0.3 4.4 2 1 2 4 4 4 1 Flagella accessory protein C (FlaC) ERM PF00769.19 CCC68747.1 - 0.012 15.4 34.6 0.038 13.8 34.4 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family RPW8 PF05659.11 CCC68747.1 - 0.013 15.2 5.9 0.013 15.2 5.9 2.6 1 1 2 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CENP-K PF11802.8 CCC68747.1 - 0.013 15.1 9.0 0.013 15.1 9.0 2.0 1 1 1 2 2 2 0 Centromere-associated protein K Spc7 PF08317.11 CCC68747.1 - 0.013 14.4 36.1 0.049 12.5 15.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein IFT57 PF10498.9 CCC68747.1 - 0.016 14.2 29.5 0.049 12.6 14.7 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 ATG16 PF08614.11 CCC68747.1 - 0.021 15.1 33.3 0.13 12.4 14.4 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GOLGA2L5 PF15070.6 CCC68747.1 - 0.022 13.4 26.7 0.028 13.1 26.7 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Fez1 PF06818.15 CCC68747.1 - 0.023 15.2 30.6 0.027 14.9 30.6 1.1 1 0 0 1 1 1 0 Fez1 WXG100 PF06013.12 CCC68747.1 - 0.029 14.6 11.5 0.27 11.5 0.9 3.9 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Taxilin PF09728.9 CCC68747.1 - 0.032 13.4 34.9 0.067 12.4 13.6 2.9 1 1 2 3 3 3 0 Myosin-like coiled-coil protein ApoLp-III PF07464.11 CCC68747.1 - 0.038 14.1 2.4 0.038 14.1 2.4 2.9 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.12 CCC68747.1 - 0.043 13.9 18.3 0.091 12.8 4.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Laminin_I PF06008.14 CCC68747.1 - 0.05 13.3 24.7 0.3 10.7 24.7 2.0 1 1 0 1 1 1 0 Laminin Domain I EzrA PF06160.12 CCC68747.1 - 0.058 11.6 30.5 0.23 9.6 30.5 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TUDOR PF00567.24 CCC68747.1 - 0.068 13.2 3.3 0.5 10.4 0.1 2.7 1 1 2 3 3 3 0 Tudor domain DUF720 PF05302.11 CCC68747.1 - 0.08 12.8 4.7 0.14 12.0 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Glyco_hydro_44 PF12891.7 CCC68747.1 - 0.088 12.7 3.3 0.12 12.3 3.3 1.3 1 1 0 1 1 1 0 Glycoside hydrolase family 44 PI3K_P85_iSH2 PF16454.5 CCC68747.1 - 0.11 12.1 29.5 0.81 9.3 28.9 2.4 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4201 PF13870.6 CCC68747.1 - 0.18 11.5 30.3 1.1 9.0 30.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) HALZ PF02183.18 CCC68747.1 - 0.22 11.8 27.5 0.15 12.3 4.4 4.1 3 1 0 3 3 2 0 Homeobox associated leucine zipper Atg14 PF10186.9 CCC68747.1 - 0.23 10.5 27.9 0.87 8.6 17.0 2.0 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF3584 PF12128.8 CCC68747.1 - 0.24 8.9 29.0 0.28 8.7 29.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3450 PF11932.8 CCC68747.1 - 0.24 10.7 29.3 0.77 9.0 14.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) TPR_MLP1_2 PF07926.12 CCC68747.1 - 0.25 11.4 41.4 7.4 6.7 7.0 3.2 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 CCC68747.1 - 0.32 11.1 29.5 0.69 10.0 13.4 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Rho_Binding PF08912.11 CCC68747.1 - 0.41 11.5 42.7 0.13 13.1 7.9 4.1 1 1 3 4 4 4 0 Rho Binding DUF4407 PF14362.6 CCC68747.1 - 0.56 9.5 18.1 0.72 9.1 18.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sec20 PF03908.13 CCC68747.1 - 0.66 9.9 11.6 3.7 7.5 0.2 2.8 1 1 2 3 3 2 0 Sec20 Rootletin PF15035.6 CCC68747.1 - 0.68 9.9 35.0 0.078 13.0 26.8 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF5595 PF18077.1 CCC68747.1 - 0.69 10.0 25.8 0.11 12.6 9.1 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5595) PRKG1_interact PF15898.5 CCC68747.1 - 0.72 10.8 34.3 2.1 9.3 17.8 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Uso1_p115_C PF04871.13 CCC68747.1 - 0.72 10.2 38.6 3.7 7.9 19.0 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region NPV_P10 PF05531.12 CCC68747.1 - 0.79 10.2 14.0 12 6.5 3.3 3.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein KASH_CCD PF14662.6 CCC68747.1 - 0.98 9.2 39.0 0.72 9.7 27.1 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH HisKA_3 PF07730.13 CCC68747.1 - 1.1 9.9 8.2 2.2 8.8 0.1 3.6 2 1 1 3 3 3 0 Histidine kinase DUF5344 PF17279.2 CCC68747.1 - 1.1 9.9 24.6 1.6 9.3 0.3 3.4 2 1 1 3 3 3 0 Family of unknown function (DUF5344) bZIP_1 PF00170.21 CCC68747.1 - 1.1 9.4 39.5 19 5.4 8.9 4.8 1 1 3 4 4 4 0 bZIP transcription factor Cortex-I_coil PF09304.10 CCC68747.1 - 1.2 9.4 31.0 8.3 6.7 9.0 3.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil Jnk-SapK_ap_N PF09744.9 CCC68747.1 - 1.2 9.3 37.9 0.26 11.5 27.0 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fzo_mitofusin PF04799.13 CCC68747.1 - 1.2 8.6 19.7 1.5 8.3 10.7 2.4 1 1 1 2 2 2 0 fzo-like conserved region DUF4200 PF13863.6 CCC68747.1 - 1.2 9.5 39.2 4.8 7.6 16.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF724 PF05266.14 CCC68747.1 - 1.3 8.8 29.5 4 7.2 12.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF4709 PF15821.5 CCC68747.1 - 1.4 9.3 15.0 0.41 11.0 8.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4709) DUF3573 PF12097.8 CCC68747.1 - 1.4 7.7 7.5 1.6 7.4 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF1640 PF07798.11 CCC68747.1 - 1.4 9.0 30.6 0.96 9.5 11.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Occludin_ELL PF07303.13 CCC68747.1 - 1.7 9.5 21.9 3.6 8.4 2.4 3.1 1 1 2 3 3 3 0 Occludin homology domain Lebercilin PF15619.6 CCC68747.1 - 1.8 8.2 34.1 10 5.8 34.1 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Sec2p PF06428.11 CCC68747.1 - 1.8 8.6 33.2 2.6 8.1 16.5 3.7 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p Spc24 PF08286.11 CCC68747.1 - 2 8.7 34.7 1.2 9.4 3.1 4.0 1 1 2 3 3 2 0 Spc24 subunit of Ndc80 YabA PF06156.13 CCC68747.1 - 2.1 9.1 27.1 1.5e+04 -3.3 27.1 2.7 1 1 0 1 1 0 0 Initiation control protein YabA DUF4795 PF16043.5 CCC68747.1 - 2.2 7.8 31.5 3.6 7.1 31.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Lectin_N PF03954.14 CCC68747.1 - 2.2 8.0 16.3 11 5.8 10.6 2.7 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain Synaptobrevin PF00957.21 CCC68747.1 - 2.3 8.0 17.8 0.075 12.8 1.6 2.9 1 1 2 3 3 3 0 Synaptobrevin Mod_r PF07200.13 CCC68747.1 - 2.7 8.1 34.7 4.4 7.4 14.8 3.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF812 PF05667.11 CCC68747.1 - 2.7 6.7 34.1 6.1 5.6 34.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Nre_C PF04895.12 CCC68747.1 - 2.8 7.9 8.0 3.5 7.6 1.6 2.6 1 1 2 3 3 3 0 Archaeal Nre, C-terminal Herpes_UL6 PF01763.16 CCC68747.1 - 3 6.3 18.7 3.9 5.9 8.4 2.3 1 1 1 2 2 2 0 Herpesvirus UL6 like Fib_alpha PF08702.10 CCC68747.1 - 3 8.0 20.1 4.7 7.4 16.6 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family SOGA PF11365.8 CCC68747.1 - 3 9.0 24.7 56 5.0 22.3 2.8 1 1 0 1 1 1 0 Protein SOGA CLZ PF16526.5 CCC68747.1 - 3 8.3 28.2 0.12 12.8 12.1 3.3 1 1 3 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Ax_dynein_light PF10211.9 CCC68747.1 - 3.3 7.6 36.5 1.4 8.8 11.4 3.2 1 1 2 3 3 3 0 Axonemal dynein light chain Nup54 PF13874.6 CCC68747.1 - 3.4 7.8 19.5 3.3 7.8 13.4 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Dynamitin PF04912.14 CCC68747.1 - 3.4 6.9 29.2 2.9 7.1 22.7 2.2 1 1 1 2 2 2 0 Dynamitin DUF745 PF05335.13 CCC68747.1 - 3.5 7.3 19.0 4.4 7.0 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TMF_DNA_bd PF12329.8 CCC68747.1 - 3.5 7.7 45.4 0.22 11.5 18.3 3.7 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.22 CCC68747.1 - 3.5 7.9 33.5 4.7 7.5 15.4 3.2 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain AAA_13 PF13166.6 CCC68747.1 - 3.6 6.1 26.6 1 7.9 11.5 1.9 1 1 1 2 2 2 0 AAA domain IZUMO PF15005.6 CCC68747.1 - 3.7 8.1 14.5 4 8.0 6.7 2.2 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated CENP-H PF05837.12 CCC68747.1 - 3.9 7.9 30.1 2 8.8 13.2 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) OmpH PF03938.14 CCC68747.1 - 4 7.8 34.7 0.95 9.8 12.3 2.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF948 PF06103.11 CCC68747.1 - 4.2 7.7 11.6 8 6.8 2.3 2.8 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF4446 PF14584.6 CCC68747.1 - 4.7 7.2 21.4 2.3 8.2 1.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) TMPIT PF07851.13 CCC68747.1 - 4.8 6.3 25.7 2.7 7.2 9.3 2.0 1 1 1 2 2 2 0 TMPIT-like protein HIP1_clath_bdg PF16515.5 CCC68747.1 - 5.5 7.7 33.2 0.5 11.0 19.5 3.0 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 HMMR_C PF15908.5 CCC68747.1 - 5.5 7.2 26.0 8.8 6.6 1.8 3.6 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor C-terminal FapA PF03961.13 CCC68747.1 - 6.1 5.3 31.4 0.98 7.9 14.4 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A SHE3 PF17078.5 CCC68747.1 - 6.6 6.4 31.0 73 3.0 31.0 2.5 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 RmuC PF02646.16 CCC68747.1 - 8.3 5.4 22.7 5.4 6.1 9.9 2.8 1 1 2 3 3 3 0 RmuC family DHR10 PF18595.1 CCC68747.1 - 8.4 6.5 36.5 1.9 8.5 15.7 2.9 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain HOOK PF05622.12 CCC68747.1 - 8.5 4.4 35.5 1.6 6.7 25.8 1.7 1 1 1 2 2 2 0 HOOK protein Fungal_TACC PF12709.7 CCC68747.1 - 8.9 6.8 33.4 3.6 8.1 4.9 4.2 1 1 2 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins YtxH PF12732.7 CCC68747.1 - 9.1 6.9 18.5 1.8e+04 -5.8 18.5 3.3 1 1 0 1 1 0 0 YtxH-like protein Nmad5 PF18757.1 CCC68747.1 - 9.4 6.4 18.1 20 5.3 0.7 2.6 1 1 0 2 2 2 0 Nucleotide modification associated domain 5 YojJ PF10372.9 CCC68747.1 - 9.5 6.4 18.6 1.2 9.3 1.0 3.7 3 1 1 4 4 3 0 Bacterial membrane-spanning protein N-terminus HORMA PF02301.18 CCC68748.1 - 7e-10 38.8 0.5 9.3e-10 38.4 0.5 1.3 1 0 0 1 1 1 1 HORMA domain FAA_hydrolase_N PF09298.11 CCC68748.1 - 0.095 12.9 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal SKG6 PF08693.10 CCC68749.1 - 5e-14 51.4 0.6 1.9e-13 49.5 0.6 2.1 1 0 0 1 1 1 1 Transmembrane alpha-helix domain He_PIG PF05345.12 CCC68749.1 - 8.4e-08 32.3 17.3 0.00024 21.2 0.0 5.1 5 0 0 5 5 4 2 Putative Ig domain DUF4448 PF14610.6 CCC68749.1 - 0.0003 20.6 0.4 0.0009 19.1 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Mid2 PF04478.12 CCC68749.1 - 0.00046 20.0 2.2 0.0014 18.5 2.2 1.9 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 CCC68749.1 - 0.0061 16.5 4.4 0.0061 16.5 4.4 2.7 2 1 1 3 3 3 1 TMEM154 protein family Adeno_E3_CR2 PF02439.15 CCC68749.1 - 0.016 15.0 0.1 0.029 14.1 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 RIFIN PF02009.16 CCC68749.1 - 0.017 15.0 0.1 0.017 15.0 0.1 1.6 2 0 0 2 2 2 0 Rifin Pox_A14 PF05767.12 CCC68749.1 - 0.019 15.1 0.0 0.046 13.9 0.0 1.6 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF3852 PF12963.7 CCC68749.1 - 0.15 12.4 0.9 0.74 10.2 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3852) GAPT PF11770.8 CCC68749.1 - 0.16 11.8 2.6 0.23 11.3 0.0 2.5 2 0 0 2 2 2 0 GRB2-binding adapter (GAPT) DUF1180 PF06679.12 CCC68749.1 - 0.38 11.2 4.0 0.17 12.3 0.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) EF-hand_4 PF12763.7 CCC68750.1 - 1.8e-48 162.8 5.7 6.9e-48 160.9 2.9 2.7 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.7 CCC68750.1 - 6e-34 118.0 8.5 2.9e-33 115.8 8.5 1.9 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.32 CCC68750.1 - 0.0014 18.0 2.1 0.0034 16.8 2.1 1.7 1 0 0 1 1 1 1 EF hand ATG16 PF08614.11 CCC68750.1 - 0.0025 18.1 10.6 0.0025 18.1 10.6 1.7 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 CCC68750.1 - 0.0032 17.1 5.2 0.0047 16.5 5.2 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit XhlA PF10779.9 CCC68750.1 - 0.01 16.0 5.3 0.072 13.3 1.0 2.8 2 0 0 2 2 2 0 Haemolysin XhlA PI3K_P85_iSH2 PF16454.5 CCC68750.1 - 0.021 14.5 5.4 0.084 12.5 0.3 2.4 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain NPV_P10 PF05531.12 CCC68750.1 - 0.033 14.6 9.7 0.55 10.7 0.2 3.5 3 1 0 4 4 3 0 Nucleopolyhedrovirus P10 protein DUF3829 PF12889.7 CCC68750.1 - 0.041 13.4 0.2 0.041 13.4 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3829) Sugarporin_N PF11471.8 CCC68750.1 - 0.075 13.0 0.2 0.24 11.4 0.0 2.0 2 0 0 2 2 1 0 Maltoporin periplasmic N-terminal extension EMP24_GP25L PF01105.24 CCC68750.1 - 0.076 13.0 1.4 8.2 6.3 0.0 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD CENP-F_leu_zip PF10473.9 CCC68750.1 - 0.12 12.4 8.7 1.5 8.9 1.7 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.11 CCC68750.1 - 0.12 12.6 9.0 0.77 10.0 1.0 2.8 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 EF-hand_6 PF13405.6 CCC68750.1 - 0.18 11.9 1.2 0.55 10.3 1.2 1.8 1 0 0 1 1 1 0 EF-hand domain vATP-synt_E PF01991.18 CCC68750.1 - 0.22 10.9 5.8 0.43 10.0 5.8 1.4 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit ABC_tran_CTD PF16326.5 CCC68750.1 - 0.25 11.6 6.0 1.5 9.1 0.4 3.1 1 1 2 3 3 3 0 ABC transporter C-terminal domain FlaC_arch PF05377.11 CCC68750.1 - 0.27 11.7 8.5 0.35 11.3 0.9 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) SAM_KSR1 PF13543.6 CCC68750.1 - 0.29 11.3 2.4 4.5 7.4 2.4 2.4 1 1 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 DUF4794 PF16042.5 CCC68750.1 - 0.32 12.0 5.0 0.11 13.5 1.8 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4794) Prefoldin_2 PF01920.20 CCC68750.1 - 0.45 10.5 6.7 1.2 9.2 1.2 2.9 2 0 0 2 2 2 0 Prefoldin subunit TcdB_N PF12918.7 CCC68750.1 - 0.5 10.7 6.4 0.59 10.5 2.6 2.7 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain MPP6 PF10175.9 CCC68750.1 - 2.5 8.6 8.0 12 6.4 0.0 2.6 2 1 0 2 2 2 0 M-phase phosphoprotein 6 Allexi_40kDa PF05549.11 CCC68750.1 - 3.8 7.0 9.9 1.7 8.1 4.9 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein Tropomyosin_1 PF12718.7 CCC68750.1 - 9.3 6.4 12.8 1.3 9.1 1.1 2.6 3 0 0 3 3 2 0 Tropomyosin like Cpn60_TCP1 PF00118.24 CCC68751.1 - 2.6e-148 494.7 9.0 3e-148 494.5 9.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family CRM1_repeat PF18777.1 CCC68751.1 - 0.15 11.6 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Chromosome region maintenance or exportin repeat MKT1_C PF12246.8 CCC68752.1 - 1.2e-57 195.0 6.6 5.1e-57 192.9 6.4 2.0 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 CCC68752.1 - 3.3e-29 101.1 0.0 1.9e-28 98.6 0.0 2.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.17 CCC68752.1 - 2.6e-20 72.8 0.0 6.9e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CCC68752.1 - 0.069 13.5 0.0 0.22 11.9 0.0 1.9 1 1 0 1 1 1 0 XPG I-region OST3_OST6 PF04756.13 CCC68753.1 - 1.3e-82 277.5 7.4 1.5e-82 277.2 7.4 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin PF00085.20 CCC68753.1 - 0.0024 17.8 0.1 0.0054 16.7 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin Voltage_CLC PF00654.20 CCC68753.1 - 0.037 13.3 4.4 0.048 12.9 3.2 1.7 1 1 0 1 1 1 0 Voltage gated chloride channel MFS_1 PF07690.16 CCC68753.1 - 0.058 12.3 7.8 0.15 11.0 7.7 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily Cytochrom_B_C PF00032.17 CCC68753.1 - 0.74 10.1 4.9 9.3 6.6 0.6 2.5 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD C2 PF00168.30 CCC68754.1 - 7.4e-68 225.3 5.5 1.6e-20 73.3 0.0 4.5 4 0 0 4 4 4 4 C2 domain SMP_LBD PF17047.5 CCC68754.1 - 0.014 14.9 0.1 0.027 13.9 0.1 1.5 1 0 0 1 1 1 0 Synaptotagmin-like mitochondrial-lipid-binding domain NT-C2 PF10358.9 CCC68754.1 - 0.064 13.0 0.2 2.8 7.7 0.0 3.0 2 0 0 2 2 2 0 N-terminal C2 in EEIG1 and EHBP1 proteins FAM35_C PF15793.5 CCC68754.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein family FAM35, C-terminal Ni_hydr_CYTB PF01292.20 CCC68754.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Ion_trans PF00520.31 CCC68755.1 - 0.0024 17.1 26.3 0.0074 15.6 26.3 1.8 1 1 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 CCC68755.1 - 0.01 14.6 18.0 0.02 13.6 14.9 2.5 2 1 0 2 2 2 0 Polycystin cation channel DUF4436 PF14494.6 CCC68755.1 - 0.23 10.7 0.8 0.35 10.1 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4436) Ras PF00071.22 CCC68756.1 - 1.2e-59 200.5 0.1 1.5e-59 200.2 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC68756.1 - 4.7e-36 123.6 0.0 6.7e-36 123.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC68756.1 - 2.1e-17 63.1 0.1 2.4e-17 62.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCC68756.1 - 2.8e-07 30.1 0.0 3.5e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCC68756.1 - 7.7e-06 26.0 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCC68756.1 - 8.8e-05 22.1 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCC68756.1 - 0.0025 17.7 0.1 1.7 8.5 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 CCC68756.1 - 0.067 13.6 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PP2C PF00481.21 CCC68757.1 - 6.5e-47 160.3 0.0 1.6e-46 159.1 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Mem_trans PF03547.18 CCC68758.1 - 2.6e-27 95.2 0.0 4.8e-27 94.3 0.0 1.4 1 1 0 1 1 1 1 Membrane transport protein Dockerin_1 PF00404.18 CCC68758.1 - 0.029 14.5 1.2 0.054 13.7 0.2 2.0 2 0 0 2 2 2 0 Dockerin type I domain TMEM219 PF14940.6 CCC68758.1 - 0.18 11.4 1.2 0.32 10.5 1.2 1.3 1 0 0 1 1 1 0 Transmembrane 219 AMP-binding PF00501.28 CCC68759.1 - 1.1e-34 119.7 0.0 1.8e-13 49.9 0.0 5.1 5 0 0 5 5 5 5 AMP-binding enzyme DMAP_binding PF06464.11 CCC68759.1 - 3.3e-12 47.2 0.2 3.3e-12 47.2 0.2 2.4 2 0 0 2 2 2 1 DMAP1-binding Domain OHA PF14418.6 CCC68759.1 - 0.067 13.0 0.2 0.28 11.0 0.2 2.1 1 0 0 1 1 1 0 OST-HTH Associated domain Arf PF00025.21 CCC68760.1 - 2.3e-71 238.9 0.4 2.7e-71 238.6 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCC68760.1 - 3e-16 59.7 0.1 4.2e-16 59.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CCC68760.1 - 1.1e-15 57.6 0.1 1.3e-15 57.3 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CCC68760.1 - 7.1e-14 51.7 0.0 8.4e-14 51.5 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CCC68760.1 - 3.4e-13 49.5 1.5 6.4e-09 35.4 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCC68760.1 - 2.3e-10 40.3 0.0 2.8e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCC68760.1 - 1.1e-06 28.7 0.0 1.7e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 CCC68760.1 - 0.13 11.5 0.2 0.22 10.8 0.2 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Rib_5-P_isom_A PF06026.14 CCC68761.1 - 1.8e-59 200.2 0.1 2.3e-59 199.9 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.22 CCC68761.1 - 0.0037 17.2 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 2 DeoR C terminal sensor domain Ribosomal_S7e PF01251.18 CCC68762.1 - 2.2e-78 262.3 2.6 2.4e-78 262.1 2.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF692 PF05114.13 CCC68762.1 - 0.078 12.2 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF692) Peptidase_U4 PF03419.13 CCC68763.1 - 0.0094 15.3 0.9 0.011 15.1 0.9 1.1 1 0 0 1 1 1 1 Sporulation factor SpoIIGA Acyltransferase PF01553.21 CCC68765.1 - 3.6e-09 36.3 0.0 1.9e-08 34.0 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Formyl_trans_N PF00551.19 CCC68766.1 - 3.5e-28 98.6 0.0 5.4e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 CCC68766.1 - 7.7e-07 29.3 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain RNA_pol_Rpb2_6 PF00562.28 CCC68766.1 - 0.13 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Glyco_transf_15 PF01793.16 CCC68767.1 - 4e-129 430.5 11.4 5.2e-129 430.2 11.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Mito_carr PF00153.27 CCC68768.1 - 1.7e-57 191.3 3.9 5.5e-20 71.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 CCC68769.1 - 8.7e-57 191.2 0.2 1.5e-56 190.5 0.2 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC68769.1 - 8.7e-21 74.4 0.0 2e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC68769.1 - 2.1e-08 33.8 0.1 3.4e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CCC68769.1 - 0.00087 19.2 4.6 0.62 10.0 0.0 3.6 2 1 1 4 4 4 2 RsgA GTPase MMR_HSR1 PF01926.23 CCC68769.1 - 0.0012 18.9 0.4 0.0026 17.8 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCC68769.1 - 0.0032 17.0 1.7 0.0093 15.5 0.1 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1_Xtn PF16897.5 CCC68769.1 - 0.057 13.4 0.8 0.41 10.7 0.0 2.6 2 1 1 3 3 3 0 C-terminal region of MMR_HSR1 domain Menin PF05053.13 CCC68769.1 - 0.18 10.1 10.7 0.26 9.6 10.7 1.2 1 0 0 1 1 1 0 Menin LMBR1 PF04791.16 CCC68769.1 - 4.3 6.1 4.3 6.2 5.6 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein MCLC PF05934.11 CCC68769.1 - 7.9 5.1 7.2 10 4.7 7.2 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF2076 PF09849.9 CCC68770.1 - 0.0014 18.8 2.1 0.0014 18.8 2.1 2.1 1 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) SNARE PF05739.19 CCC68771.1 - 1.3e-12 47.5 2.1 2.5e-12 46.6 2.1 1.5 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 CCC68771.1 - 0.00011 21.9 1.7 0.00011 21.9 1.7 2.2 3 0 0 3 3 3 1 Synaptobrevin TMPIT PF07851.13 CCC68771.1 - 0.0038 16.5 4.2 0.0053 16.1 4.2 1.2 1 0 0 1 1 1 1 TMPIT-like protein Prominin PF05478.11 CCC68771.1 - 0.0089 14.0 5.5 0.012 13.6 5.5 1.3 1 0 0 1 1 1 1 Prominin DUF4268 PF14088.6 CCC68771.1 - 0.037 13.9 1.2 0.067 13.1 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4268) FeoB_Cyto PF17910.1 CCC68771.1 - 0.094 13.3 2.1 0.18 12.4 2.1 1.6 1 0 0 1 1 1 0 FeoB cytosolic helical domain Spc7 PF08317.11 CCC68771.1 - 0.14 11.0 15.3 0.32 9.8 15.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein MCU PF04678.13 CCC68771.1 - 0.18 11.9 10.8 1.7 8.7 10.6 2.1 1 1 0 1 1 1 0 Mitochondrial calcium uniporter T2SSF PF00482.23 CCC68771.1 - 0.22 11.5 0.2 0.22 11.5 0.2 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F Use1 PF09753.9 CCC68771.1 - 0.25 11.0 14.9 2.6 7.7 14.9 2.0 1 1 0 1 1 1 0 Membrane fusion protein Use1 OppC_N PF12911.7 CCC68771.1 - 0.58 10.2 1.9 1.3 9.1 1.9 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Orf78 PF06024.12 CCC68771.1 - 4.5 7.6 10.9 0.45 10.8 0.4 2.5 1 1 1 2 2 2 0 Orf78 (ac78) DUF3552 PF12072.8 CCC68772.1 - 0.073 12.5 2.7 0.13 11.7 2.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) bZIP_2 PF07716.15 CCC68772.1 - 0.37 10.9 9.9 0.036 14.1 4.0 2.5 2 0 0 2 2 2 0 Basic region leucine zipper PspB PF06667.12 CCC68772.1 - 2.7 8.1 5.6 0.35 11.0 0.8 2.0 3 0 0 3 3 3 0 Phage shock protein B RGS PF00615.19 CCC68773.1 - 7.1e-09 36.0 1.2 2.3e-08 34.3 1.2 1.9 1 0 0 1 1 1 1 Regulator of G protein signaling domain UPF0449 PF15136.6 CCC68773.1 - 1 9.9 5.5 0.46 11.0 0.3 3.0 1 1 0 2 2 2 0 Uncharacterised protein family UPF0449 HMGL-like PF00682.19 CCC68774.1 - 3.5e-90 302.1 0.0 5.5e-90 301.5 0.0 1.3 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 CCC68774.1 - 8e-29 100.2 1.4 2.5e-28 98.6 1.4 1.9 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Syja_N PF02383.18 CCC68775.1 - 5.3e-76 256.0 0.1 8.5e-76 255.3 0.1 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CCC68775.1 - 5.5e-15 55.5 0.0 8.8e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.16 CCC68776.1 - 5.5e-35 119.2 1.4 8.5e-35 118.6 1.4 1.3 1 0 0 1 1 1 1 YEATS family THOC7 PF05615.13 CCC68776.1 - 0.092 13.0 0.5 0.96 9.7 0.7 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 TFIIIC_sub6 PF10419.9 CCC68777.1 - 6.8e-24 83.6 0.5 1.4e-23 82.5 0.5 1.5 1 0 0 1 1 1 1 TFIIIC subunit triple barrel domain His_Phos_1 PF00300.22 CCC68777.1 - 3.8e-16 59.3 0.0 9.3e-16 58.1 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) UL73_N PF12522.8 CCC68777.1 - 0.65 9.8 3.3 1.6 8.5 3.3 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Pox_Ag35 PF03286.14 CCC68777.1 - 0.71 9.6 10.5 0.042 13.6 4.2 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF2072 PF09845.9 CCC68777.1 - 2.9 8.1 7.5 2.6 8.3 1.0 2.4 2 1 0 2 2 2 0 Zn-ribbon containing protein Maf PF02545.14 CCC68778.1 - 1.9e-38 131.9 0.0 2.2e-38 131.7 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein HEAT PF02985.22 CCC68779.1 - 0.0012 18.9 0.0 3.5 8.1 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.6 CCC68779.1 - 0.003 18.0 0.2 26 5.5 0.0 4.4 4 0 0 4 4 4 1 HEAT-like repeat CLASP_N PF12348.8 CCC68779.1 - 0.0055 16.3 0.1 2 7.9 0.0 2.8 1 1 1 3 3 3 2 CLASP N terminal Cnd1 PF12717.7 CCC68779.1 - 0.012 15.6 0.6 1.9 8.5 0.1 2.5 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CCC68779.1 - 0.022 15.4 0.2 24 5.6 0.0 3.3 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region zf-H2C2_2 PF13465.6 CCC68780.1 - 4.2e-21 74.4 23.3 6.3e-10 39.0 1.2 4.5 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.26 CCC68780.1 - 7.7e-21 73.3 26.1 1.3e-05 25.4 0.8 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC68780.1 - 2.6e-12 46.4 23.2 0.0033 18.1 0.3 4.6 4 0 0 4 4 4 4 C2H2-type zinc finger zf-Di19 PF05605.12 CCC68780.1 - 0.00014 22.1 4.4 0.0089 16.3 0.3 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.7 CCC68780.1 - 0.00027 21.2 14.9 0.00059 20.1 0.3 4.7 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCC68780.1 - 0.00033 20.8 13.1 0.0083 16.4 0.1 4.1 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCC68780.1 - 0.039 13.9 23.6 0.12 12.4 1.2 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger zf-CHCC PF10276.9 CCC68780.1 - 0.13 12.3 11.9 2.4 8.3 0.1 3.2 3 0 0 3 3 3 0 Zinc-finger domain PyrI_C PF02748.15 CCC68780.1 - 0.45 10.5 6.9 14 5.7 0.1 3.6 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.15 CCC68780.1 - 1.1 9.4 16.0 3.8 7.6 0.6 3.9 2 1 1 3 3 3 0 BED zinc finger DZR PF12773.7 CCC68780.1 - 1.2 9.3 4.2 7.3 6.7 3.5 2.3 1 1 1 2 2 2 0 Double zinc ribbon C1_4 PF07975.12 CCC68780.1 - 1.3 9.3 4.3 6 7.2 0.8 3.0 1 1 1 2 2 2 0 TFIIH C1-like domain zf-C2HC_2 PF13913.6 CCC68780.1 - 4.4 7.3 13.8 0.63 10.0 0.1 4.1 4 0 0 4 4 4 0 zinc-finger of a C2HC-type zf-Dof PF02701.15 CCC68780.1 - 7.1 6.9 9.7 10 6.3 3.8 3.4 1 1 1 2 2 2 0 Dof domain, zinc finger TRAPP PF04051.16 CCC68781.1 - 6.4e-33 113.5 0.0 9.5e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component SH3_9 PF14604.6 CCC68782.1 - 1.9e-25 88.4 0.0 1.3e-13 50.6 0.1 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 CCC68782.1 - 1e-23 82.7 0.1 1.1e-10 40.9 0.0 2.5 2 0 0 2 2 2 2 SH3 domain FCH PF00611.23 CCC68782.1 - 7.8e-19 67.7 0.3 3.6e-18 65.6 0.3 2.3 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.17 CCC68782.1 - 2.7e-12 46.2 0.0 5.3e-08 32.4 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain MatP_C PF17414.2 CCC68782.1 - 0.024 14.8 0.1 0.094 12.9 0.1 2.0 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain DUF4600 PF15372.6 CCC68782.1 - 0.078 13.4 0.4 0.078 13.4 0.4 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4600) FHA PF00498.26 CCC68783.1 - 2.6e-11 43.7 0.0 6.2e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 CCC68783.1 - 2.6e-10 39.8 5.3 7.5e-10 38.4 4.3 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 CCC68783.1 - 2.6e-07 30.9 7.0 6.6e-07 29.6 7.0 1.8 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 CCC68783.1 - 6e-05 23.3 0.0 0.00035 20.8 0.0 2.2 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-rbx1 PF12678.7 CCC68783.1 - 0.0023 18.1 3.4 0.0071 16.6 3.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CCC68783.1 - 0.0026 17.6 6.6 0.0067 16.3 6.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCC68783.1 - 0.0056 16.6 5.8 0.014 15.3 5.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 CCC68783.1 - 0.018 15.1 3.0 0.06 13.4 3.0 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.29 CCC68783.1 - 0.022 14.6 6.0 0.051 13.5 4.4 2.4 2 0 0 2 2 2 0 PHD-finger zf-C3HC4_2 PF13923.6 CCC68783.1 - 0.045 13.6 6.9 0.11 12.3 6.9 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC68783.1 - 0.24 11.5 6.2 0.29 11.2 4.0 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.6 CCC68783.1 - 0.46 10.3 4.8 1.1 9.1 4.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CHCH PF06747.13 CCC68784.1 - 1.3e-05 25.1 5.6 2.7e-05 24.2 5.6 1.6 1 1 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 CCC68784.1 - 0.00026 21.1 5.3 0.00038 20.6 5.3 1.2 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Pet191_N PF10203.9 CCC68784.1 - 0.21 11.9 7.5 0.36 11.2 7.5 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 TPR_2 PF07719.17 CCC68785.1 - 2.1e-25 86.7 25.8 0.00011 22.0 0.0 10.6 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.28 CCC68785.1 - 4.2e-23 80.1 26.9 2.3e-05 24.0 1.8 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_8 PF13181.6 CCC68785.1 - 2.8e-19 67.7 25.4 0.00079 19.5 0.1 9.5 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 CCC68785.1 - 2.4e-15 56.9 0.8 0.0027 18.3 0.0 5.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 CCC68785.1 - 2.7e-14 53.4 14.3 0.0014 19.1 1.9 6.0 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 CCC68785.1 - 4e-14 52.0 19.5 0.003 17.2 0.1 8.1 6 3 2 8 8 8 5 TPR repeat TPR_14 PF13428.6 CCC68785.1 - 2.6e-12 46.5 4.1 2.6 9.1 0.1 7.8 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCC68785.1 - 1e-10 41.2 13.8 0.0059 16.9 0.1 7.7 8 1 0 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCC68785.1 - 5.4e-08 33.0 9.9 0.34 11.2 0.0 6.9 3 3 3 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC68785.1 - 2.8e-06 27.5 13.8 0.034 14.4 0.2 4.8 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CCC68785.1 - 7.5e-06 26.0 0.0 0.28 11.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.8 CCC68785.1 - 0.00018 20.6 11.9 0.035 13.0 0.1 3.8 2 1 2 4 4 4 2 NMDA receptor-regulated protein 1 TPR_7 PF13176.6 CCC68785.1 - 0.00043 20.1 5.6 11 6.4 0.0 6.1 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_MalT PF17874.1 CCC68785.1 - 0.0014 18.1 0.2 0.0039 16.6 0.2 1.8 1 0 0 1 1 1 1 MalT-like TPR region TPR_6 PF13174.6 CCC68785.1 - 0.01 16.4 14.2 10 7.0 0.1 7.4 7 0 0 7 7 6 0 Tetratricopeptide repeat Sel1 PF08238.12 CCC68785.1 - 0.019 15.6 8.0 4.3 8.2 0.0 5.7 7 0 0 7 7 5 0 Sel1 repeat RPN7 PF10602.9 CCC68785.1 - 0.023 14.4 2.4 0.62 9.8 0.1 3.6 3 1 0 3 3 3 0 26S proteasome subunit RPN7 SPO22 PF08631.10 CCC68785.1 - 0.041 13.4 0.8 0.34 10.4 0.1 2.5 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like DUF3808 PF10300.9 CCC68785.1 - 0.053 12.3 6.4 1.5 7.5 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3808) SNAP PF14938.6 CCC68785.1 - 0.19 11.1 13.1 0.28 10.6 0.3 4.0 3 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP DUF3856 PF12968.7 CCC68785.1 - 0.25 11.4 1.9 8.6 6.4 0.1 3.5 3 1 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_21 PF09976.9 CCC68785.1 - 0.94 9.1 6.8 11 5.7 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 CCC68785.1 - 1.1 9.4 5.8 32 4.7 0.1 4.2 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat NSF PF02071.20 CCC68785.1 - 1.4 10.0 3.5 1.5e+02 3.9 0.0 4.8 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat ORC6 PF05460.13 CCC68786.1 - 1.7e-91 307.2 1.2 2.1e-91 306.9 1.2 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) N-SET PF11764.8 CCC68787.1 - 7.2e-48 162.9 3.1 7.2e-48 162.9 3.1 1.9 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.28 CCC68787.1 - 6.7e-19 68.9 0.6 5.1e-18 66.0 0.1 2.7 2 1 0 2 2 2 1 SET domain SET_assoc PF11767.8 CCC68787.1 - 4.3e-18 64.7 0.5 1.1e-17 63.4 0.5 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated MutS_V PF00488.21 CCC68788.1 - 2.6e-66 223.3 0.0 5.2e-66 222.3 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCC68788.1 - 1.3e-32 113.6 3.2 4.6e-32 111.8 3.2 2.0 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 CCC68788.1 - 2.9e-24 85.5 0.0 7.8e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 CCC68788.1 - 4.8e-10 39.8 0.0 4.8e-10 39.8 0.0 2.3 3 0 0 3 3 3 1 MutS domain II Urm1 PF09138.11 CCC68788.1 - 0.073 13.4 1.2 5.7 7.4 0.0 3.5 3 0 0 3 3 3 0 Urm1 (Ubiquitin related modifier) ABC_tran PF00005.27 CCC68788.1 - 0.096 13.2 0.4 2.3 8.7 0.0 2.9 2 1 0 2 2 2 0 ABC transporter AAA_23 PF13476.6 CCC68788.1 - 0.15 12.6 0.1 0.15 12.6 0.1 3.9 3 2 2 5 5 5 0 AAA domain NPC1_N PF16414.5 CCC68788.1 - 0.24 10.9 0.0 0.43 10.1 0.0 1.3 1 0 0 1 1 1 0 Niemann-Pick C1 N terminus FeS_assembly_P PF01883.19 CCC68789.1 - 3.4e-06 27.1 0.0 8.1e-06 25.9 0.0 1.7 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein CDP-OH_P_transf PF01066.21 CCC68790.1 - 2.4e-15 57.0 0.1 2.4e-15 57.0 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NDT80_PhoG PF05224.12 CCC68791.1 - 4.9e-59 199.7 0.5 4.9e-59 199.7 0.5 2.0 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family Hydin_ADK PF17213.3 CCC68791.1 - 3.9 7.7 8.6 4.3 7.6 6.7 2.0 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF1140 PF06600.11 CCC68791.1 - 5.3 7.5 6.7 12 6.4 2.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1140) DUF3605 PF12239.8 CCC68792.1 - 4.9e-39 134.1 2.9 6.9e-39 133.6 2.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) CAP_GLY PF01302.25 CCC68794.1 - 9.6e-17 60.8 0.4 1.5e-16 60.2 0.4 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.6 CCC68794.1 - 2.9e-08 34.1 0.1 6.5e-08 32.9 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain LSM PF01423.22 CCC68795.1 - 8.4e-14 51.0 0.0 1.3e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain UPRTase PF14681.6 CCC68796.1 - 5.2e-76 254.7 0.0 6.6e-76 254.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 CCC68796.1 - 0.0023 17.5 0.0 0.0028 17.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 CCC68796.1 - 0.16 12.0 0.1 0.26 11.3 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.19 CCC68797.1 - 5.1e-111 371.2 0.0 4.3e-110 368.1 0.0 1.8 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 CCC68797.1 - 0.056 12.6 0.0 0.092 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative actin-like family MreB_Mbl PF06723.13 CCC68797.1 - 0.13 11.1 0.0 8.9 5.0 0.0 2.5 2 1 0 2 2 2 0 MreB/Mbl protein MFA1_2 PF17317.2 CCC68798.1 - 8.7e-16 57.4 0.8 9.3e-16 57.3 0.8 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 PH PF00169.29 CCC68799.1 - 0.019 15.5 1.4 0.61 10.6 1.4 2.7 1 1 0 1 1 1 0 PH domain PH_9 PF15410.6 CCC68799.1 - 0.17 12.3 1.3 0.61 10.5 1.3 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain FAM176 PF14851.6 CCC68799.1 - 0.24 11.1 2.9 20 4.8 5.9 2.3 2 0 0 2 2 2 0 FAM176 family NOA36 PF06524.12 CCC68799.1 - 1.4 8.2 6.6 2.2 7.5 6.6 1.3 1 0 0 1 1 1 0 NOA36 protein WRNPLPNID PF15017.6 CCC68799.1 - 3.1 8.7 9.9 8.6 7.3 9.9 1.7 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box DUF4611 PF15387.6 CCC68799.1 - 3.3 8.0 8.0 8.8 6.6 8.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) CENP-B_dimeris PF09026.10 CCC68799.1 - 8.3 6.9 16.9 3.5 8.1 14.0 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Peptidase_M14 PF00246.24 CCC68800.1 - 1.9e-73 247.8 0.1 1.2e-72 245.2 0.0 1.9 2 0 0 2 2 2 1 Zinc carboxypeptidase Endosulfine PF04667.17 CCC68801.1 - 1.9e-32 111.3 0.6 3.3e-32 110.5 0.6 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region INSIG PF07281.12 CCC68802.1 - 2.4e-17 63.3 3.4 1.5e-16 60.7 3.4 2.1 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) WLM PF08325.10 CCC68803.1 - 2.2e-62 210.6 0.1 2.8e-62 210.2 0.1 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 CCC68803.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF45 Pkinase PF00069.25 CCC68804.1 - 3.5e-26 92.1 0.0 8.1e-26 91.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68804.1 - 4.3e-13 49.1 0.0 9.4e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC68804.1 - 6.9e-09 35.0 0.0 6.9e-09 35.0 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CCC68804.1 - 0.16 11.9 1.5 4.1 7.3 0.1 3.0 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 CCC68804.1 - 1.4 7.8 3.8 1.4 7.9 0.1 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase PPP4R2 PF09184.11 CCC68804.1 - 1.9 8.0 16.9 3.4 7.2 16.9 1.3 1 0 0 1 1 1 0 PPP4R2 RNA_pol_3_Rpc31 PF11705.8 CCC68805.1 - 1.4 9.1 9.9 2.4 8.3 9.9 1.3 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Aminotran_1_2 PF00155.21 CCC68806.1 - 1.6e-18 67.0 0.0 2.8e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3860 PF12976.7 CCC68806.1 - 0.068 13.2 0.0 0.28 11.2 0.0 2.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) Glucodextran_C PF09985.9 CCC68807.1 - 0.079 12.4 0.0 0.08 12.4 0.0 1.0 1 0 0 1 1 1 0 C-terminal binding-module, SLH-like, of glucodextranase Inhibitor_I9 PF05922.16 CCC68807.1 - 0.1 13.3 0.1 0.35 11.6 0.1 1.9 1 1 0 1 1 1 0 Peptidase inhibitor I9 YlbE PF14003.6 CCC68807.1 - 0.11 13.0 0.0 0.25 11.8 0.0 1.6 1 1 1 2 2 2 0 YlbE-like protein RRM_1 PF00076.22 CCC68808.1 - 4.4e-41 138.5 9.5 5e-16 58.3 0.1 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCC68808.1 - 7.6e-07 28.9 0.2 1 9.3 0.1 3.8 3 0 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CCC68808.1 - 2.2e-06 27.6 0.1 0.025 14.6 0.0 3.4 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 CCC68808.1 - 2.7e-06 27.4 1.9 0.21 11.7 0.0 3.7 4 0 0 4 4 4 2 Limkain b1 RRM_3 PF08777.11 CCC68808.1 - 0.00066 19.7 4.9 0.33 11.0 0.3 4.2 4 0 0 4 4 4 1 RNA binding motif Nup35_RRM PF05172.13 CCC68808.1 - 0.004 17.1 1.5 0.025 14.5 0.2 2.8 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 CCC68808.1 - 0.028 14.5 0.1 18 5.6 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif RL PF17797.1 CCC68808.1 - 1.7 8.6 5.3 1.2 9.2 0.1 3.1 3 1 1 4 4 4 0 RL domain Ysc84 PF04366.12 CCC68809.1 - 1e-41 141.6 0.1 1.8e-41 140.8 0.1 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator SH3_1 PF00018.28 CCC68809.1 - 3.4e-17 61.8 0.0 6.4e-17 60.9 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCC68809.1 - 5.9e-13 48.4 0.0 1.1e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCC68809.1 - 2.8e-12 46.1 0.0 5.6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain LEA_5 PF00477.17 CCC68809.1 - 0.032 14.7 0.4 0.07 13.6 0.4 1.5 1 0 0 1 1 1 0 Small hydrophilic plant seed protein PHP PF02811.19 CCC68810.1 - 2.1e-12 47.7 1.8 4.2e-12 46.7 1.8 1.5 1 1 0 1 1 1 1 PHP domain Acetyltransf_13 PF13880.6 CCC68811.1 - 3.7e-22 78.1 0.1 7.8e-22 77.0 0.1 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 CCC68811.1 - 3.2e-11 42.9 0.2 5.4e-11 42.1 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 CCC68811.1 - 0.0003 21.0 0.0 0.0005 20.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCC68811.1 - 0.0067 16.4 0.0 0.015 15.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCC68811.1 - 0.0075 16.7 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DSPn PF14671.6 CCC68812.1 - 2.2e-45 154.5 0.5 7.9e-45 152.8 0.1 2.0 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 CCC68812.1 - 1.3e-24 86.5 0.0 1e-22 80.4 0.0 2.5 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCC68812.1 - 0.00022 20.9 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 CCC68812.1 - 0.00091 18.9 0.6 0.0031 17.2 0.2 1.9 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 CCC68812.1 - 0.013 15.7 0.0 0.029 14.5 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Adap_comp_sub PF00928.21 CCC68812.1 - 0.05 13.0 0.3 0.079 12.3 0.3 1.2 1 0 0 1 1 1 0 Adaptor complexes medium subunit family WD40 PF00400.32 CCC68813.1 - 0.0046 17.8 0.0 0.69 10.9 0.0 4.2 4 0 0 4 4 4 1 WD domain, G-beta repeat COMPASS-Shg1 PF05205.12 CCC68814.1 - 2.6e-27 95.5 2.3 3.1e-27 95.3 2.3 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 EnY2 PF10163.9 CCC68814.1 - 0.059 13.8 1.0 0.13 12.7 1.0 1.5 1 0 0 1 1 1 0 Transcription factor e(y)2 DUF3825 PF12873.7 CCC68815.1 - 0.033 13.7 1.6 2.2 7.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3825) DUF5071 PF16804.5 CCC68815.1 - 0.25 11.6 2.2 15 5.8 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) RhoGAP PF00620.27 CCC68816.1 - 5.6e-42 143.1 1.4 2.3e-40 137.9 0.0 2.5 2 1 0 2 2 2 1 RhoGAP domain FCH PF00611.23 CCC68816.1 - 8.7e-06 25.9 7.5 0.00026 21.2 7.5 2.7 1 1 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Prominin PF05478.11 CCC68816.1 - 0.029 12.4 3.7 0.04 11.9 3.7 1.3 1 0 0 1 1 1 0 Prominin Sec34 PF04136.15 CCC68816.1 - 0.16 11.8 6.8 0.029 14.2 1.8 2.2 2 0 0 2 2 2 0 Sec34-like family Methyltransf_PK PF05891.12 CCC68817.1 - 7.2e-92 306.8 0.0 8.2e-92 306.6 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 CCC68817.1 - 1.3e-05 25.8 0.0 2.7e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCC68817.1 - 5.4e-05 23.1 0.0 0.00016 21.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC68817.1 - 0.003 18.2 0.0 0.011 16.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 CCC68817.1 - 0.0033 16.7 0.0 0.0056 16.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Bin3 PF06859.12 CCC68817.1 - 0.036 14.7 0.0 0.064 13.9 0.0 1.4 1 0 0 1 1 1 0 Bicoid-interacting protein 3 (Bin3) AIM5 PF17050.5 CCC68818.1 - 4.1e-06 27.5 0.1 4.9e-06 27.3 0.1 1.3 1 1 0 1 1 1 1 Altered inheritance of mitochondria 5 SHMT PF00464.19 CCC68819.1 - 2.2e-204 678.6 0.0 2.6e-204 678.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Ras PF00071.22 CCC68820.1 - 1.7e-45 154.5 0.1 2.3e-45 154.1 0.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC68820.1 - 5.6e-33 113.7 0.1 9e-33 113.0 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC68820.1 - 1.2e-16 60.7 0.1 1.7e-16 60.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCC68820.1 - 1.1e-06 28.2 0.0 1.5e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CCC68820.1 - 8.3e-05 22.1 0.0 0.00016 21.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CCC68820.1 - 0.00011 22.3 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CCC68820.1 - 0.00022 20.5 0.6 0.16 11.1 0.1 2.5 1 1 1 2 2 2 2 G-protein alpha subunit RsgA_GTPase PF03193.16 CCC68820.1 - 0.0035 17.3 0.0 2.2 8.1 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CCC68820.1 - 0.02 14.4 0.0 0.31 10.6 0.0 2.4 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain TniB PF05621.11 CCC68820.1 - 0.021 14.2 0.0 0.061 12.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 CCC68820.1 - 0.026 14.9 0.0 0.048 14.0 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 CCC68820.1 - 0.057 13.4 0.8 0.2 11.7 0.8 1.8 1 1 0 1 1 1 0 AAA domain Rif1_N PF12231.8 CCC68821.1 - 2.4e-44 151.8 7.6 4.8e-44 150.9 7.6 1.4 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Pkinase PF00069.25 CCC68822.1 - 5.9e-61 206.1 0.0 7.9e-61 205.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68822.1 - 4.8e-35 121.1 0.0 6.5e-35 120.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC68822.1 - 2.2e-09 37.0 0.0 3.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCC68822.1 - 6.1e-05 22.0 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CCC68822.1 - 0.00044 19.4 0.1 0.0057 15.7 0.0 2.1 2 0 0 2 2 2 1 Seadornavirus VP7 Haspin_kinase PF12330.8 CCC68822.1 - 0.0017 17.4 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CCC68822.1 - 0.0046 16.3 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CCC68822.1 - 0.041 13.5 0.0 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase Cytochrom_B_N_2 PF13631.6 CCC68822.1 - 0.1 12.6 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 0 Cytochrome b(N-terminal)/b6/petB UBX PF00789.20 CCC68823.1 - 5.2e-18 65.0 0.0 1.3e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 UBX domain DUF3408 PF11888.8 CCC68823.1 - 0.0047 17.1 3.1 0.0047 17.1 3.1 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3408) HSM3_N PF18795.1 CCC68824.1 - 1.7e-111 371.4 15.4 3e-111 370.6 15.4 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein HSM3, N terminal domain HSM3_C PF18794.1 CCC68824.1 - 3.9e-86 287.1 4.7 3.9e-86 287.1 4.7 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein HSM3, C terminal domain Methyltransf_16 PF10294.9 CCC68825.1 - 5.9e-25 88.0 0.0 8.8e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CCC68825.1 - 1.1e-09 38.4 0.0 2e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC68825.1 - 2.5e-07 30.6 0.0 5.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCC68825.1 - 4.5e-05 24.1 0.0 0.00011 22.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 CCC68825.1 - 0.00027 20.7 0.0 0.00053 19.7 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 CCC68825.1 - 0.00091 19.8 0.0 0.0023 18.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC68825.1 - 0.0014 19.3 0.1 0.0035 18.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CCC68825.1 - 0.0028 17.2 0.0 0.0047 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Macro PF01661.21 CCC68825.1 - 0.2 11.7 0.0 2.7 8.1 0.0 2.2 1 1 1 2 2 2 0 Macro domain HbrB PF08539.11 CCC68826.1 - 1.9e-36 125.6 0.7 1.9e-36 125.6 0.7 2.1 2 1 0 2 2 2 1 HbrB-like DAP PF15228.6 CCC68826.1 - 1.1 10.5 3.7 2.3 9.4 2.7 2.0 2 0 0 2 2 2 0 Death-associated protein DUF1674 PF07896.12 CCC68827.1 - 7.5e-18 64.7 3.6 1.7e-17 63.6 3.6 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Ribosomal_L37 PF08561.10 CCC68828.1 - 7.6e-24 84.5 10.1 9.8e-19 68.0 0.7 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 zf-C2H2_2 PF12756.7 CCC68829.1 - 9.4e-36 122.2 6.2 3.3e-32 110.8 2.3 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CCC68829.1 - 0.011 16.1 3.9 0.056 13.7 0.8 3.0 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NOA36 PF06524.12 CCC68829.1 - 0.011 15.1 1.7 0.011 15.1 1.7 3.1 2 1 1 3 3 3 0 NOA36 protein DUF2024 PF09630.10 CCC68829.1 - 0.016 15.1 0.7 0.044 13.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2024) PP_kinase_C PF13090.6 CCC68829.1 - 0.042 13.3 0.5 0.042 13.3 0.5 2.0 1 1 1 2 2 2 0 Polyphosphate kinase C-terminal domain 2 DUF1460 PF07313.12 CCC68829.1 - 0.13 11.6 1.5 0.24 10.8 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1460) zf-C2H2_4 PF13894.6 CCC68829.1 - 1.1 10.3 9.3 1.1 10.3 0.3 3.8 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.26 CCC68829.1 - 5 7.8 10.8 1.3 9.6 0.8 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type adh_short PF00106.25 CCC68830.1 - 1.8e-19 70.0 0.0 6.9e-18 64.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CCC68830.1 - 3.1e-13 50.1 0.0 4.3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 CCC68830.1 - 2.3e-08 33.9 0.0 2.6e-07 30.4 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.15 CCC68830.1 - 0.0076 15.4 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Sacchrp_dh_NADP PF03435.18 CCC68830.1 - 0.18 12.1 0.0 0.28 11.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Cyt_b-c1_8 PF10890.8 CCC68831.1 - 0.068 13.6 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Cytochrome b-c1 complex subunit 8 FixQ PF05545.11 CCC68831.1 - 0.23 11.5 1.1 0.37 10.8 1.1 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Mrpl_C PF18502.1 CCC68832.1 - 1.4e-37 128.3 2.1 1.4e-37 128.3 2.1 1.7 2 1 0 2 2 2 1 54S ribosomal protein L8 C-terminal domain Ribosomal_L17 PF01196.19 CCC68832.1 - 4.2e-29 101.3 1.1 1.8e-28 99.3 0.0 2.2 2 1 0 2 2 2 1 Ribosomal protein L17 AIM5 PF17050.5 CCC68832.1 - 0.054 14.3 0.2 0.14 12.9 0.2 1.7 1 0 0 1 1 1 0 Altered inheritance of mitochondria 5 DSPc PF00782.20 CCC68833.1 - 4.8e-26 91.2 0.0 3.9e-21 75.3 0.0 3.7 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCC68833.1 - 0.00013 21.6 0.2 0.00031 20.4 0.2 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CCC68833.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate RE_SinI PF09570.10 CCC68833.1 - 0.11 11.7 0.0 0.26 10.5 0.0 1.5 1 0 0 1 1 1 0 SinI restriction endonuclease Peptidase_M1 PF01433.20 CCC68834.1 - 0.0057 16.2 0.1 0.018 14.6 0.1 1.8 1 0 0 1 1 1 1 Peptidase family M1 domain Paf1 PF03985.13 CCC68836.1 - 8.1e-98 328.2 10.7 9e-98 328.0 10.7 1.0 1 0 0 1 1 1 1 Paf1 RCC1_2 PF13540.6 CCC68837.1 - 5.3e-17 61.1 5.5 2.2e-05 24.1 0.1 5.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 CCC68837.1 - 2.7e-14 53.5 0.6 0.0017 18.9 0.4 5.8 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Peptidase_M20 PF01546.28 CCC68838.1 - 2.3e-25 89.5 0.0 4e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CCC68838.1 - 1.6e-11 44.1 0.0 3.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.32 CCC68838.1 - 1.7e-10 41.3 5.2 0.054 14.4 0.0 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC68838.1 - 0.0024 18.1 0.0 0.97 9.8 0.0 3.1 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M42 PF05343.14 CCC68838.1 - 0.087 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase MRP-L27 PF09809.9 CCC68839.1 - 4.5e-34 116.7 1.6 6.7e-34 116.1 1.6 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 SecY PF00344.20 CCC68840.1 - 9.4e-39 133.5 19.8 1.3e-38 133.0 19.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CCC68840.1 - 4.1e-09 36.1 0.5 4.1e-09 36.1 0.5 2.6 2 0 0 2 2 2 1 Plug domain of Sec61p A_deaminase PF00962.22 CCC68841.1 - 2.4e-25 89.6 0.0 1.5e-11 44.2 0.0 3.6 2 2 0 3 3 3 3 Adenosine/AMP deaminase DUF3781 PF12636.7 CCC68841.1 - 0.22 11.4 4.0 0.36 10.7 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) Peptidase_M28 PF04389.17 CCC68842.1 - 1.1e-38 133.0 0.2 1.5e-38 132.5 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CCC68842.1 - 8.1e-08 32.2 0.0 1.8e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.28 CCC68842.1 - 0.00029 20.6 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.14 CCC68842.1 - 0.018 14.1 0.0 0.043 12.8 0.0 1.6 2 0 0 2 2 2 0 M42 glutamyl aminopeptidase Mem_trans PF03547.18 CCC68843.1 - 1.1e-64 218.3 16.8 9.1e-64 215.2 16.8 1.9 1 1 0 1 1 1 1 Membrane transport protein Cytokin_check_N PF10407.9 CCC68844.1 - 2.1e-30 104.5 2.0 2.1e-30 104.5 2.0 2.1 2 0 0 2 2 2 1 Cdc14 phosphatase binding protein N-terminus CAP PF00188.26 CCC68846.1 - 7.8e-17 62.3 3.4 1.9e-16 61.1 3.4 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Hamartin PF04388.12 CCC68846.1 - 3.7 6.1 4.9 4.6 5.8 4.9 1.2 1 0 0 1 1 1 0 Hamartin protein Ras PF00071.22 CCC68847.1 - 4.9e-55 185.5 0.5 6.1e-55 185.2 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC68847.1 - 3.5e-37 127.3 0.1 6.4e-37 126.4 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC68847.1 - 9.8e-15 54.4 0.2 1.4e-14 53.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCC68847.1 - 9.5e-07 28.4 0.1 1.2e-06 28.1 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCC68847.1 - 4.4e-06 26.8 0.0 6.7e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCC68847.1 - 6.3e-05 22.9 1.0 0.27 11.1 0.1 2.7 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 CCC68847.1 - 0.00016 21.3 0.1 0.00031 20.3 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Septin PF00735.18 CCC68847.1 - 0.0048 16.2 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Septin TniB PF05621.11 CCC68847.1 - 0.022 14.2 0.0 0.046 13.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 CCC68847.1 - 0.034 14.5 0.1 0.052 13.9 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Polyoma_agno PF01736.16 CCC68847.1 - 0.068 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Polyomavirus agnoprotein Mitofilin PF09731.9 CCC68848.1 - 4e-31 108.6 17.9 1.1e-30 107.1 13.0 2.0 2 0 0 2 2 2 2 Mitochondrial inner membrane protein GCIP PF13324.6 CCC68848.1 - 0.015 14.9 5.6 0.028 14.0 5.6 1.4 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting SseC PF04888.12 CCC68848.1 - 0.068 12.8 2.2 0.098 12.2 2.2 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family SlyX PF04102.12 CCC68848.1 - 0.36 11.5 0.1 0.36 11.5 0.1 3.1 3 0 0 3 3 3 0 SlyX IBR PF01485.21 CCC68849.1 - 2.1e-19 69.5 42.2 9.4e-12 45.0 4.7 4.0 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 CCC68849.1 - 1.1e-05 25.2 13.5 1.1e-05 25.2 13.5 5.0 4 2 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) DUF3808 PF10300.9 CCC68850.1 - 1.1e-175 585.0 2.9 1.3e-175 584.8 2.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 CCC68850.1 - 0.022 15.1 1.1 1.7 9.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 CCC68850.1 - 0.16 12.2 0.7 28 5.2 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCC68850.1 - 0.18 12.3 0.2 0.18 12.3 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCC68850.1 - 0.19 12.4 5.0 0.43 11.3 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 CCC68850.1 - 1.2 9.9 9.8 3.1 8.7 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_4 PF12763.7 CCC68851.1 - 0.0016 18.4 0.7 0.009 15.9 0.0 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF3876 PF12992.7 CCC68851.1 - 0.095 12.8 0.2 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) Vps51 PF08700.11 CCC68852.1 - 3.6e-12 46.2 1.2 7.5e-12 45.2 1.2 1.6 1 0 0 1 1 1 1 Vps51/Vps67 HBS1_N PF08938.10 CCC68852.1 - 0.028 14.7 0.7 0.028 14.7 0.7 2.4 2 1 1 3 3 3 0 HBS1 N-terminus DUF4050 PF13259.6 CCC68852.1 - 0.08 13.3 2.0 0.095 13.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) Trypan_PARP PF05887.11 CCC68852.1 - 0.16 11.9 4.9 0.21 11.6 4.9 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Arrestin_C PF02752.22 CCC68853.1 - 4.7e-12 46.5 0.3 2.5e-11 44.2 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCC68853.1 - 2.2e-08 34.3 0.1 5e-05 23.4 0.1 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain NTR2 PF15458.6 CCC68854.1 - 1.9e-121 405.4 35.7 2.2e-121 405.2 35.7 1.0 1 0 0 1 1 1 1 Nineteen complex-related protein 2 Thioredoxin_5 PF13743.6 CCC68854.1 - 0.02 14.5 3.3 0.055 13.1 1.2 2.4 2 0 0 2 2 2 0 Thioredoxin DUF2730 PF10805.8 CCC68854.1 - 0.48 10.5 6.6 0.31 11.1 0.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) SAPS PF04499.15 CCC68855.1 - 4.1e-170 566.8 8.4 4.1e-170 566.8 8.4 3.3 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein ChAPs PF09295.10 CCC68856.1 - 1e-40 140.0 4.6 2.6e-31 109.0 1.1 2.3 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.17 CCC68856.1 - 8.2e-06 25.6 3.6 0.066 13.4 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC68856.1 - 0.0016 18.6 0.1 0.0069 16.6 0.1 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 CCC68856.1 - 0.0073 16.4 0.0 0.023 14.8 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat GCS PF03074.16 CCC68857.1 - 4.4e-151 503.4 0.3 5.5e-151 503.1 0.3 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase IF-2B PF01008.17 CCC68858.1 - 2.2e-77 260.0 0.0 2.6e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.22 CCC68858.1 - 0.085 12.8 0.2 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 DeoR C terminal sensor domain Sin_N PF04801.13 CCC68859.1 - 6.2e-18 65.2 0.8 1e-17 64.5 0.8 1.3 1 1 0 1 1 1 1 Sin-like protein conserved region DEAD PF00270.29 CCC68860.1 - 2.5e-39 134.8 0.0 4.6e-39 134.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.6 CCC68860.1 - 5.1e-17 61.9 0.1 1.3e-16 60.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.31 CCC68860.1 - 2.4e-16 60.1 0.0 1.1e-15 57.9 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC68860.1 - 7.2e-05 22.9 0.5 0.00022 21.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C2HC5 PF06221.13 CCC68861.1 - 1.1e-21 76.5 6.0 1.9e-21 75.8 6.0 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type Ribosomal_L24e PF01246.20 CCC68861.1 - 0.037 14.2 0.2 4.6 7.6 0.0 3.0 2 0 0 2 2 2 0 Ribosomal protein L24e Peptidase_C37 PF05416.12 CCC68861.1 - 0.2 10.2 5.4 0.38 9.2 5.4 1.6 1 0 0 1 1 1 0 Southampton virus-type processing peptidase zf-C2H2_3rep PF18868.1 CCC68861.1 - 1.7 9.3 7.4 0.81 10.4 0.4 3.2 1 1 2 3 3 3 0 Zinc finger C2H2-type, 3 repeats PHD PF00628.29 CCC68862.1 - 1.1e-07 31.7 9.3 2.4e-07 30.6 9.3 1.6 1 0 0 1 1 1 1 PHD-finger SET PF00856.28 CCC68862.1 - 5.9e-07 30.0 0.0 2e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 SET domain PHD_2 PF13831.6 CCC68862.1 - 0.016 14.8 3.7 0.029 13.9 3.7 1.4 1 0 0 1 1 1 0 PHD-finger UNC-50 PF05216.13 CCC68863.1 - 1.6e-89 299.2 22.7 1.9e-89 299.0 22.7 1.0 1 0 0 1 1 1 1 UNC-50 family PLDc PF00614.22 CCC68864.1 - 5.8e-18 64.3 1.4 2.9e-09 36.7 0.4 3.3 3 0 0 3 3 3 2 Phospholipase D Active site motif PLDc_2 PF13091.6 CCC68864.1 - 3.6e-12 46.3 0.6 6.3e-07 29.4 0.1 3.6 3 1 0 3 3 3 2 PLD-like domain PX PF00787.24 CCC68864.1 - 2.4e-05 24.3 4.8 0.0028 17.6 0.3 4.1 3 0 0 3 3 3 1 PX domain PH_2 PF08458.10 CCC68864.1 - 9.7e-05 22.7 2.2 0.00022 21.5 0.9 2.2 2 0 0 2 2 2 1 Plant pleckstrin homology-like region PH PF00169.29 CCC68864.1 - 0.069 13.7 3.7 0.079 13.5 1.7 2.3 2 0 0 2 2 2 0 PH domain DUF2783 PF10932.8 CCC68864.1 - 0.17 11.6 0.0 0.57 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2783) GATA PF00320.27 CCC68865.1 - 5.3e-14 51.5 3.0 9.8e-14 50.7 3.0 1.5 1 0 0 1 1 1 1 GATA zinc finger W_rich_C PF07483.11 CCC68865.1 - 0.056 13.6 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan-rich Synechocystis species C-terminal domain TF_Zn_Ribbon PF08271.12 CCC68865.1 - 0.12 11.9 0.5 0.29 10.7 0.5 1.6 1 1 0 1 1 1 0 TFIIB zinc-binding Snf7 PF03357.21 CCC68866.1 - 1.7e-08 34.3 22.3 1.7e-08 34.3 22.3 1.4 1 1 0 1 1 1 1 Snf7 DUF5414 PF17435.2 CCC68866.1 - 0.02 14.5 2.9 0.028 14.1 2.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5414) HD_2 PF12917.7 CCC68866.1 - 0.11 12.3 6.2 0.18 11.5 6.2 1.3 1 0 0 1 1 1 0 HD containing hydrolase-like enzyme DMSP_lyase PF16867.5 CCC68866.1 - 0.41 10.3 0.1 0.41 10.3 0.1 1.8 3 0 0 3 3 3 0 Dimethlysulfonioproprionate lyase DUF948 PF06103.11 CCC68866.1 - 3.7 7.9 11.5 0.85 9.9 1.4 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) LMBR1 PF04791.16 CCC68866.1 - 7 5.4 6.4 8.8 5.1 6.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Cpn60_TCP1 PF00118.24 CCC68867.1 - 1.5e-157 525.2 4.2 1.7e-157 525.0 4.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Pyr_redox_2 PF07992.14 CCC68867.1 - 0.006 15.8 0.2 0.075 12.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Herpes_U59 PF04529.12 CCC68867.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus U59 protein WD40 PF00400.32 CCC68868.1 - 2.5e-25 88.2 13.1 4.1e-06 27.4 0.1 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC68868.1 - 8.4e-09 35.6 1.3 0.0092 16.3 0.0 5.4 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCC68868.1 - 9.7e-06 24.5 7.8 0.00028 19.7 0.5 4.3 1 1 4 5 5 5 1 Nucleoporin Nup120/160 WD40_like PF17005.5 CCC68868.1 - 0.00013 21.4 3.1 0.0065 15.8 0.1 3.1 2 1 1 3 3 3 1 WD40-like domain Caf4 PF11615.8 CCC68868.1 - 0.0029 17.5 0.3 0.0078 16.1 0.0 1.9 2 0 0 2 2 2 1 CCR4-associated factor 4 PQQ_2 PF13360.6 CCC68868.1 - 0.0076 15.9 0.3 0.14 11.7 0.0 2.6 1 1 1 3 3 3 1 PQQ-like domain NUP214 PF16755.5 CCC68868.1 - 0.024 13.9 2.5 0.042 13.1 0.0 2.4 2 1 1 3 3 3 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 5-FTHF_cyc-lig PF01812.20 CCC68869.1 - 7.9e-43 146.5 0.0 9e-43 146.3 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DASH_Spc34 PF08657.10 CCC68870.1 - 4.9e-90 301.8 7.3 5.5e-90 301.6 7.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 Atg14 PF10186.9 CCC68870.1 - 0.006 15.7 3.9 0.006 15.7 3.9 1.6 2 0 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 Bacillus_HBL PF05791.11 CCC68870.1 - 0.0066 16.3 5.6 0.052 13.4 3.6 2.2 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) Occludin_ELL PF07303.13 CCC68870.1 - 0.019 15.7 2.4 0.019 15.7 2.4 2.1 2 0 0 2 2 2 0 Occludin homology domain LemA PF04011.12 CCC68870.1 - 0.023 14.5 0.5 0.048 13.5 0.5 1.5 1 0 0 1 1 1 0 LemA family TolA_bind_tri PF16331.5 CCC68870.1 - 0.024 14.7 3.6 0.14 12.2 2.0 2.5 1 1 1 2 2 2 0 TolA binding protein trimerisation OmpH PF03938.14 CCC68870.1 - 0.23 11.8 5.5 0.51 10.7 5.5 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF1664 PF07889.12 CCC68870.1 - 0.38 10.8 2.8 0.81 9.7 2.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ABC_tran_CTD PF16326.5 CCC68870.1 - 1.4 9.2 8.8 6.3 7.1 3.7 2.7 3 0 0 3 3 3 0 ABC transporter C-terminal domain DivIC PF04977.15 CCC68870.1 - 1.7 8.5 7.8 15 5.5 1.1 3.0 1 1 2 3 3 3 0 Septum formation initiator TMF_DNA_bd PF12329.8 CCC68870.1 - 1.8 8.6 12.1 4.3 7.4 5.8 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Peptidase_M22 PF00814.25 CCC68871.1 - 1.9e-84 283.5 0.0 2.4e-84 283.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 CCC68871.1 - 0.049 13.3 0.0 0.065 12.9 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase N-terminus F1F0-ATPsyn_F PF10791.9 CCC68872.1 - 1e-05 25.9 1.2 0.75 10.3 0.0 3.9 1 1 2 3 3 3 2 Mitochondrial F1-F0 ATP synthase subunit F of fungi NTF2 PF02136.20 CCC68872.1 - 0.054 14.1 0.0 66 4.1 0.0 3.4 3 0 0 3 3 3 0 Nuclear transport factor 2 (NTF2) domain DUF2059 PF09832.9 CCC68872.1 - 0.087 12.9 0.1 26 4.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2059) Glyco_hydro_65C PF03633.15 CCC68873.1 - 0.16 11.9 0.6 37 4.3 0.0 3.6 4 0 0 4 4 4 0 Glycosyl hydrolase family 65, C-terminal domain FeS_assembly_P PF01883.19 CCC68873.1 - 3.2 8.0 4.8 6 7.1 0.4 3.1 3 0 0 3 3 3 0 Iron-sulfur cluster assembly protein AA_permease PF00324.21 CCC68874.1 - 4.6e-147 490.5 38.5 5.3e-147 490.3 38.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC68874.1 - 9.8e-37 126.8 41.1 1.2e-36 126.5 41.1 1.1 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 CCC68874.1 - 0.019 15.5 0.1 0.059 13.9 0.1 1.8 1 0 0 1 1 1 0 Pet100 VASP_tetra PF08776.11 CCC68874.1 - 0.72 9.5 4.2 1.2 8.8 4.2 1.3 1 0 0 1 1 1 0 VASP tetramerisation domain SUN PF03856.13 CCC68875.1 - 2.8e-99 331.5 13.0 2.8e-99 331.5 13.0 1.5 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) Dehydrin PF00257.19 CCC68875.1 - 0.35 11.4 3.1 1.2 9.7 3.1 1.9 1 0 0 1 1 1 0 Dehydrin His_Phos_1 PF00300.22 CCC68876.1 - 2.1e-34 118.9 0.1 2.7e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 CCC68876.1 - 0.0013 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lectin_leg-like PF03388.13 CCC68877.1 - 0.00011 21.6 0.1 0.00053 19.4 0.0 1.9 2 0 0 2 2 2 1 Legume-like lectin family DUF1831 PF08866.10 CCC68877.1 - 0.038 14.4 0.2 0.1 13.1 0.1 1.7 1 1 0 1 1 1 0 Putative amino acid metabolism PET10 PF17316.2 CCC68879.1 - 1.5e-89 299.8 3.6 2e-89 299.4 3.6 1.1 1 0 0 1 1 1 1 Petite colonies protein 10 TrkH PF02386.16 CCC68880.1 - 1.9e-171 570.9 3.6 7.8e-171 568.9 0.2 2.1 2 0 0 2 2 2 2 Cation transport protein Vps54 PF07928.12 CCC68880.1 - 0.023 15.1 0.2 0.065 13.7 0.2 1.8 1 0 0 1 1 1 0 Vps54-like protein Menin PF05053.13 CCC68880.1 - 5.1 5.3 6.7 0.99 7.7 1.0 2.0 2 0 0 2 2 2 0 Menin DUF2462 PF09495.10 CCC68881.1 - 0.59 10.9 4.1 3.4 8.5 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) LSM PF01423.22 CCC68882.1 - 2.4e-15 56.0 0.3 4.6e-15 55.1 0.3 1.4 1 0 0 1 1 1 1 LSM domain Dimer_Tnp_hAT PF05699.14 CCC68883.1 - 7.5e-09 35.3 0.1 2.9e-08 33.4 0.1 2.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CCC68883.1 - 0.076 13.0 3.5 0.22 11.6 3.5 1.9 1 0 0 1 1 1 0 BED zinc finger zinc_ribbon_4 PF13717.6 CCC68883.1 - 0.16 11.9 0.9 0.35 10.8 0.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Terminase_GpA PF05876.12 CCC68883.1 - 0.18 10.3 0.1 0.27 9.7 0.1 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) DUF1687 PF07955.11 CCC68884.1 - 7.5e-24 84.6 0.1 9.4e-24 84.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) TPR_16 PF13432.6 CCC68885.1 - 2.9e-18 66.2 0.6 0.024 15.3 0.0 5.7 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_19 PF14559.6 CCC68885.1 - 5.4e-13 49.3 9.8 1e-06 29.2 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCC68885.1 - 4.4e-12 45.1 20.9 0.031 14.4 0.1 10.3 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCC68885.1 - 5.1e-12 45.9 7.1 0.0039 17.4 0.0 6.9 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 CCC68885.1 - 9.4e-12 44.2 19.9 0.0048 16.7 0.2 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_6 PF13174.6 CCC68885.1 - 3.1e-10 40.0 10.4 0.0089 16.6 0.0 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 CCC68885.1 - 1.4e-09 37.4 23.3 0.17 12.2 0.1 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCC68885.1 - 4.2e-09 36.2 7.7 0.45 11.0 0.2 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC68885.1 - 2.2e-05 24.6 9.2 1.4 9.2 0.1 5.2 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 CCC68885.1 - 0.00039 21.0 2.3 0.77 10.7 0.0 5.4 4 2 2 6 6 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCC68885.1 - 0.00068 19.3 15.9 0.055 13.2 0.6 5.0 5 1 0 5 5 5 2 TPR repeat TPR_9 PF13371.6 CCC68885.1 - 0.00083 19.5 0.1 5 7.3 0.0 4.3 5 1 1 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.6 CCC68885.1 - 0.002 17.4 0.0 0.99 8.6 0.0 3.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 CCC68885.1 - 0.0034 17.3 5.2 3.9 7.7 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCC68885.1 - 0.21 11.7 1.4 16 5.7 0.1 3.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 CCC68885.1 - 0.31 11.0 4.3 7.7 6.5 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 CCC68885.1 - 2 8.1 7.0 7.2 6.3 0.8 4.3 4 1 0 5 5 5 0 26S proteasome subunit RPN7 UFD1 PF03152.14 CCC68886.1 - 1.3e-70 236.4 0.0 1.7e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 ArAE_2_N PF10337.9 CCC68887.1 - 4.2e-50 171.1 4.3 4.2e-50 171.1 4.3 2.7 3 1 0 3 3 3 1 Putative ER transporter, 6TM, N-terminal FUSC_2 PF13515.6 CCC68887.1 - 3.7e-11 43.2 16.5 3.7e-11 43.2 16.5 3.2 2 2 0 2 2 2 1 Fusaric acid resistance protein-like ArAE_2 PF10334.9 CCC68887.1 - 7.5e-05 22.7 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 ALMT PF11744.8 CCC68887.1 - 9.3e-05 21.4 20.7 0.011 14.6 18.5 3.2 2 1 0 2 2 2 2 Aluminium activated malate transporter NAP PF00956.18 CCC68888.1 - 4e-86 288.6 5.8 4e-86 288.6 5.8 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Drc1-Sld2 PF11719.8 CCC68888.1 - 0.02 14.5 12.1 0.035 13.7 12.1 1.5 1 1 0 1 1 1 0 DNA replication and checkpoint protein Ribosomal_L6 PF00347.23 CCC68888.1 - 0.051 14.2 0.4 0.13 12.9 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L6 Solute_trans_a PF03619.16 CCC68889.1 - 2.6e-74 250.1 16.2 3.2e-74 249.8 16.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha FixP_N PF14715.6 CCC68889.1 - 1.7 8.4 6.2 1.7 8.5 2.7 2.8 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Mito_carr PF00153.27 CCC68890.1 - 3.5e-62 206.3 5.0 2.9e-21 75.2 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein Neurensin PF14927.6 CCC68890.1 - 0.068 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Neurensin PAP2 PF01569.21 CCC68891.1 - 9.8e-14 51.3 1.2 2.6e-13 49.9 1.2 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.6 CCC68891.1 - 0.46 10.1 7.5 0.16 11.7 4.3 2.0 2 1 0 2 2 2 0 PAP2 superfamily AAA_6 PF12774.7 CCC68892.1 - 2.4e-98 329.1 0.1 1.7e-97 326.3 0.0 2.7 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 CCC68892.1 - 5.6e-85 285.8 7.7 5.6e-85 285.8 7.7 6.5 8 1 1 9 9 7 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 CCC68892.1 - 1.8e-55 187.5 1.7 1.8e-55 187.5 1.7 6.1 5 0 0 5 5 4 1 ATP-binding dynein motor region DHC_N1 PF08385.12 CCC68892.1 - 3.7e-48 164.5 19.4 3.7e-48 164.5 19.4 3.7 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 1 AAA_8 PF12780.7 CCC68892.1 - 8.7e-44 149.8 0.5 3.8e-43 147.7 0.5 2.3 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 CCC68892.1 - 1.7e-37 128.7 0.9 4.3e-32 111.1 0.0 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region MT PF12777.7 CCC68892.1 - 1.9e-29 102.8 3.5 4.3e-29 101.6 3.5 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 CCC68892.1 - 3.8e-26 91.7 0.4 6.2e-10 39.2 0.0 6.0 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_lid_11 PF18198.1 CCC68892.1 - 3.1e-20 72.6 0.0 1.7e-19 70.3 0.0 2.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 CCC68892.1 - 3.4e-14 53.0 0.0 4.4e-12 46.2 0.0 3.8 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA PF00004.29 CCC68892.1 - 4.8e-14 52.9 0.9 0.0021 18.5 0.0 6.7 7 0 0 7 7 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCC68892.1 - 9.9e-12 45.3 8.8 0.00019 21.7 0.0 7.5 8 0 0 8 8 6 2 AAA domain AAA_33 PF13671.6 CCC68892.1 - 2.7e-09 37.3 0.2 0.0013 18.9 0.0 4.8 5 0 0 5 5 5 1 AAA domain AAA_16 PF13191.6 CCC68892.1 - 7.1e-09 36.3 0.0 0.29 11.5 0.0 5.3 4 0 0 4 4 3 3 AAA ATPase domain AAA_18 PF13238.6 CCC68892.1 - 1.2e-08 35.5 0.6 0.36 11.4 0.0 5.6 5 0 0 5 5 4 2 AAA domain AAA_14 PF13173.6 CCC68892.1 - 2.6e-07 30.7 0.7 0.065 13.3 0.0 6.0 5 0 0 5 5 5 1 AAA domain cobW PF02492.19 CCC68892.1 - 1.8e-05 24.4 0.4 0.0073 15.9 0.0 3.0 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 CCC68892.1 - 4.2e-05 23.9 0.4 2.8 8.4 0.0 4.4 4 0 0 4 4 3 1 RNA helicase T2SSE PF00437.20 CCC68892.1 - 4.9e-05 22.5 0.4 0.036 13.1 0.0 3.5 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_30 PF13604.6 CCC68892.1 - 4.9e-05 23.1 1.6 8.1 6.1 0.0 4.4 4 0 0 4 4 4 0 AAA domain AAA_28 PF13521.6 CCC68892.1 - 8.9e-05 22.8 0.5 11 6.2 0.1 4.7 4 0 0 4 4 4 0 AAA domain ABC_tran PF00005.27 CCC68892.1 - 0.00013 22.5 0.5 4.2 7.9 0.0 5.3 4 0 0 4 4 4 1 ABC transporter NACHT PF05729.12 CCC68892.1 - 0.00027 20.9 0.2 1.3 9.0 0.0 3.6 3 0 0 3 3 3 2 NACHT domain Zeta_toxin PF06414.12 CCC68892.1 - 0.00041 19.7 0.0 1.1 8.5 0.0 3.2 3 0 0 3 3 3 2 Zeta toxin NB-ARC PF00931.22 CCC68892.1 - 0.00081 18.6 0.1 0.85 8.8 0.1 2.9 2 0 0 2 2 2 2 NB-ARC domain AAA_19 PF13245.6 CCC68892.1 - 0.00091 19.6 10.5 2.6 8.4 0.0 5.2 5 0 0 5 5 5 2 AAA domain IstB_IS21 PF01695.17 CCC68892.1 - 0.0012 18.6 0.1 2 8.1 0.0 3.6 3 0 0 3 3 3 1 IstB-like ATP binding protein Roc PF08477.13 CCC68892.1 - 0.0013 18.9 0.4 1.9 8.7 0.0 3.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CCC68892.1 - 0.0022 17.8 9.2 2.8 7.6 0.0 5.1 5 0 0 5 5 4 1 AAA domain AAA_lid_1 PF17857.1 CCC68892.1 - 0.0032 17.7 0.8 0.25 11.6 0.0 3.9 3 0 0 3 3 2 1 AAA+ lid domain TsaE PF02367.17 CCC68892.1 - 0.035 14.1 3.4 27 4.8 0.1 4.6 5 0 0 5 5 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CCC68892.1 - 0.053 12.9 3.1 0.41 10.0 0.1 3.7 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 CCC68892.1 - 0.055 12.8 0.1 3.1 7.1 0.1 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 CCC68892.1 - 0.16 11.7 4.1 3 7.7 0.1 3.9 4 0 0 4 4 4 0 P-loop containing region of AAA domain NTPase_1 PF03266.15 CCC68892.1 - 0.4 10.6 7.7 6.5 6.6 0.0 3.8 4 0 0 4 4 3 0 NTPase ResIII PF04851.15 CCC68892.1 - 2.2 8.2 4.9 13 5.7 0.0 4.2 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CCC68892.1 - 2.3 7.9 17.2 3.7 7.2 0.0 5.5 5 0 0 5 5 5 0 AAA domain Ras PF00071.22 CCC68893.1 - 4e-48 163.1 0.0 5.2e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC68893.1 - 1.4e-21 77.0 0.0 3.3e-21 75.7 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 CCC68893.1 - 6.9e-06 26.1 0.0 0.0033 17.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 CCC68893.1 - 0.00018 21.0 0.0 0.00026 20.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 CCC68893.1 - 0.09 12.5 0.0 0.77 9.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain tRNA_U5-meth_tr PF05958.11 CCC68894.1 - 9.1e-23 80.8 0.1 3e-21 75.8 0.1 2.7 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.20 CCC68894.1 - 1.1e-11 44.5 0.1 2.6e-11 43.4 0.1 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.6 CCC68894.1 - 5.4e-08 32.8 0.0 3.6e-07 30.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCC68894.1 - 2e-06 28.4 0.1 6.4e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 CCC68894.1 - 2.8e-06 27.0 0.2 0.00011 21.8 0.1 2.5 2 1 0 2 2 2 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 CCC68894.1 - 1.7e-05 24.4 0.0 3.2e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 CCC68894.1 - 2.7e-05 23.9 0.0 4.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.14 CCC68894.1 - 0.00013 21.5 0.0 0.00039 20.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 CCC68894.1 - 0.00026 20.4 0.0 0.0055 16.1 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 CCC68894.1 - 0.0067 17.1 0.0 0.029 15.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 CCC68894.1 - 0.01 15.6 0.5 0.064 13.0 0.0 2.4 3 0 0 3 3 3 0 Met-10+ like-protein Ribosomal_S21e PF01249.18 CCC68895.1 - 2.7e-39 133.1 0.1 3e-39 133.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Glyco_hydro2_C5 PF18565.1 CCC68895.1 - 0.026 14.4 0.1 0.031 14.1 0.1 1.1 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 VCH_CASS14 PF18315.1 CCC68895.1 - 0.049 13.7 0.0 0.084 12.9 0.0 1.5 1 1 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain Glyco_transf_8 PF01501.20 CCC68896.1 - 1.7e-26 93.3 0.3 1.7e-26 93.3 0.3 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 8 Retrotrans_gag PF03732.17 CCC68896.1 - 0.069 13.4 1.0 0.25 11.6 0.9 2.0 1 1 0 1 1 1 0 Retrotransposon gag protein DEAD PF00270.29 CCC68897.1 - 4.7e-44 150.2 1.4 5.4e-44 150.1 0.3 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC68897.1 - 5.1e-31 107.3 0.2 1.7e-30 105.6 0.1 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC68897.1 - 1e-07 32.2 0.0 2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCC68897.1 - 0.001 18.9 0.1 0.0017 18.1 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCC68897.1 - 0.0012 19.2 0.1 0.013 15.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain Ribosomal_L1 PF00687.21 CCC68898.1 - 2.6e-44 151.4 1.0 3.1e-44 151.2 1.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Crust_neurohorm PF01147.17 CCC68898.1 - 0.092 12.6 0.4 0.25 11.2 0.4 1.7 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family Glyco_transf_15 PF01793.16 CCC68899.1 - 2e-103 346.1 13.1 2.4e-103 345.8 13.1 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RNA_pol_Rpb4 PF03874.16 CCC68900.1 - 5.1e-35 120.5 13.5 5.3e-32 110.7 2.2 2.3 1 1 0 2 2 2 2 RNA polymerase Rpb4 SURF2 PF05477.11 CCC68900.1 - 0.18 11.4 13.5 0.24 11.1 13.5 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) LRIF1 PF15741.5 CCC68900.1 - 0.54 8.7 11.4 0.65 8.5 11.4 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Drc1-Sld2 PF11719.8 CCC68900.1 - 0.62 9.6 16.6 0.86 9.1 16.6 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein SUIM_assoc PF16619.5 CCC68900.1 - 0.68 10.0 7.7 0.071 13.2 2.6 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Rtf2 PF04641.12 CCC68900.1 - 0.79 9.0 9.7 1.1 8.6 9.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger IncFII_repA PF02387.15 CCC68900.1 - 0.99 8.6 6.5 1.4 8.1 5.5 1.7 2 0 0 2 2 2 0 IncFII RepA protein family NPR3 PF03666.13 CCC68900.1 - 1.5 7.6 9.4 2.3 6.9 9.4 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SLC12 PF03522.15 CCC68900.1 - 2.4 7.1 10.2 3.1 6.7 10.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 TFA2_Winged_2 PF18121.1 CCC68901.1 - 2.4e-20 72.0 0.0 7.9e-20 70.3 0.0 2.0 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 TFIIE_beta PF02186.15 CCC68901.1 - 1.3e-15 57.5 0.7 2.9e-15 56.3 0.7 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain NUC PF18510.1 CCC68901.1 - 0.12 12.9 1.2 0.4 11.1 0.0 2.1 2 0 0 2 2 2 0 Nuclease domain HTH_15 PF12324.8 CCC68901.1 - 0.18 11.8 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase RNA_polI_A34 PF08208.11 CCC68902.1 - 1.5e-27 97.0 13.6 1.5e-27 97.0 13.6 1.4 2 0 0 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 Ufm1 PF03671.14 CCC68902.1 - 0.019 15.0 0.1 0.21 11.7 0.0 2.4 3 0 0 3 3 3 0 Ubiquitin fold modifier 1 protein Peptidase_S49_N PF08496.10 CCC68902.1 - 9.9 6.2 14.0 33 4.5 11.4 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Las1 PF04031.13 CCC68903.1 - 5.2e-48 163.0 1.7 5.2e-48 163.0 1.7 1.9 2 0 0 2 2 2 1 Las1-like PAC1 PF16094.5 CCC68903.1 - 1 8.4 5.3 2.1 7.5 5.3 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 Zn_clus PF00172.18 CCC68904.1 - 3.8e-08 33.3 8.9 8.5e-08 32.2 8.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGEF67_u2 PF16614.5 CCC68904.1 - 0.03 14.4 0.2 0.082 13.0 0.2 1.7 1 0 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 Pam17 PF08566.10 CCC68905.1 - 3.6e-68 228.6 0.0 4.6e-68 228.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 peroxidase PF00141.23 CCC68906.1 - 9.4e-40 136.7 0.0 1.6e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Vps35 PF03635.17 CCC68907.1 - 5.9e-268 891.3 33.5 6.8e-268 891.1 33.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 PIR PF00399.19 CCC68908.1 - 7e-63 207.0 124.7 4.6e-08 32.4 5.5 10.4 5 4 5 10 10 10 9 Yeast PIR protein repeat TFIIA PF03153.13 CCC68908.1 - 0.73 9.8 20.6 0.89 9.5 20.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CHMI PF02962.15 CCC68908.1 - 4.5 7.6 6.6 29 5.0 0.4 2.7 1 1 1 3 3 3 0 5-carboxymethyl-2-hydroxymuconate isomerase Hamartin PF04388.12 CCC68908.1 - 9.3 4.8 8.1 12 4.5 8.1 1.0 1 0 0 1 1 1 0 Hamartin protein PIR PF00399.19 CCC68909.1 - 5.7e-59 194.6 100.3 7.8e-09 34.9 7.6 7.9 8 0 0 8 8 8 7 Yeast PIR protein repeat DUF2807 PF10988.8 CCC68909.1 - 0.48 10.2 15.4 0.73 9.6 14.2 1.8 1 1 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain DUF4097 PF13349.6 CCC68909.1 - 8.5 5.6 22.7 22 4.3 6.5 1.8 1 1 1 2 2 2 0 Putative adhesin PigN PF04987.14 CCC68910.1 - 2.1e-130 435.6 51.1 3e-130 435.1 51.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 CCC68910.1 - 1.9e-10 40.9 3.5 3.5e-09 36.7 3.5 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 CCC68910.1 - 3.1e-10 39.9 0.1 5.5e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.18 CCC68910.1 - 1.1e-05 24.9 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily MFS_1 PF07690.16 CCC68911.1 - 1.9e-21 76.4 8.0 5.9e-16 58.3 1.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 CCC68912.1 - 4.6e-69 232.7 0.0 7e-69 232.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68912.1 - 7.7e-37 127.0 0.0 1e-36 126.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC68912.1 - 0.00026 20.4 0.0 0.00046 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCC68912.1 - 0.03 14.2 0.0 0.081 12.8 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family L51_S25_CI-B8 PF05047.16 CCC68913.1 - 1.9e-12 46.9 0.4 3.7e-12 46.0 0.2 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Arf PF00025.21 CCC68913.1 - 0.022 14.2 0.0 0.036 13.5 0.0 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family Pkinase PF00069.25 CCC68914.1 - 1.2e-43 149.4 0.4 1.1e-42 146.2 0.4 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68914.1 - 8.3e-19 67.9 0.0 2.1e-18 66.6 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCC68914.1 - 0.0039 16.6 0.2 0.008 15.6 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CCC68914.1 - 0.026 14.1 0.1 0.026 14.1 0.1 2.3 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 CCC68914.1 - 0.063 12.9 0.0 0.18 11.4 0.0 1.8 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 CCC68914.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 CCC68914.1 - 0.098 12.6 0.1 0.18 11.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L14 PF00238.19 CCC68915.1 - 3.7e-42 143.3 1.2 4.2e-42 143.1 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.25 CCC68916.1 - 3e-41 141.6 0.0 5.3e-26 91.6 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68916.1 - 1.8e-23 83.2 0.0 7.7e-18 64.7 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 CCC68916.1 - 0.021 14.2 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 CCC68916.1 - 0.083 12.2 0.0 7.8 5.7 0.0 2.3 2 0 0 2 2 2 0 Kinase-like polyprenyl_synt PF00348.17 CCC68917.1 - 5.3e-97 323.9 0.3 6.4e-97 323.6 0.3 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Med28 PF11594.8 CCC68917.1 - 0.015 15.4 0.1 0.038 14.1 0.1 1.7 1 0 0 1 1 1 0 Mediator complex subunit 28 GTP_EFTU PF00009.27 CCC68918.1 - 1.1e-41 142.5 0.0 1.7e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CCC68918.1 - 2.4e-16 59.5 0.0 6.8e-16 58.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 CCC68918.1 - 1.2e-13 50.8 0.0 2.1e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFTUD2 PF16004.5 CCC68918.1 - 9.9e-12 45.5 4.8 2.3e-10 41.1 4.8 2.3 1 1 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus GTP_EFTU_D2 PF03144.25 CCC68918.1 - 0.00011 22.6 0.0 0.00023 21.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CCC68918.1 - 0.0002 21.4 0.0 0.00043 20.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CCC68918.1 - 0.00084 19.4 0.2 0.0024 17.9 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 CCC68918.1 - 0.0029 17.2 0.3 0.015 14.9 0.2 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CCC68918.1 - 0.0039 17.4 0.1 0.34 11.2 0.1 2.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Erf4 PF10256.9 CCC68918.1 - 0.12 12.5 0.0 0.51 10.5 0.0 2.2 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family RAMA PF18755.1 CCC68918.1 - 0.14 12.6 0.0 0.31 11.5 0.0 1.5 1 0 0 1 1 1 0 Restriction Enzyme Adenine Methylase Associated AA_permease PF00324.21 CCC68919.1 - 1.5e-78 264.5 45.0 1.8e-78 264.3 45.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC68919.1 - 1.9e-41 142.3 49.7 2.4e-41 142.0 49.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF423 PF04241.15 CCC68919.1 - 5.2 7.4 6.4 20 5.4 0.3 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF423) Zip PF02535.22 CCC68920.1 - 3.2e-25 89.1 12.2 7.1e-25 87.9 12.2 1.5 1 1 0 1 1 1 1 ZIP Zinc transporter DUF4203 PF13886.6 CCC68920.1 - 0.015 15.0 0.1 0.015 15.0 0.1 2.8 3 1 0 4 4 4 0 Domain of unknown function (DUF4203) CSG2 PF16965.5 CCC68920.1 - 0.024 13.6 0.7 0.057 12.4 0.7 1.6 1 0 0 1 1 1 0 Ceramide synthase regulator DUF4481 PF14800.6 CCC68920.1 - 0.034 13.6 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4481) MerC PF03203.14 CCC68920.1 - 1.6 9.2 7.4 0.088 13.3 0.5 2.3 2 1 0 2 2 2 0 MerC mercury resistance protein Longin_2 PF18639.1 CCC68921.1 - 1.1e-64 217.3 3.9 2.1e-64 216.3 3.9 1.5 1 0 0 1 1 1 1 Yeast longin domain DUF2401 PF10287.9 CCC68922.1 - 1.3e-84 283.4 2.0 1.3e-84 283.4 2.0 1.5 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.9 CCC68922.1 - 1.4e-24 86.3 0.0 3.3e-24 85.1 0.0 1.7 1 0 0 1 1 1 1 Glycine-rich protein domain (DUF2403) STE3 PF02076.15 CCC68923.1 - 5.3e-87 291.7 20.0 6.6e-87 291.4 20.0 1.1 1 0 0 1 1 1 1 Pheromone A receptor FXR_C1 PF16096.5 CCC68923.1 - 0.079 13.2 0.6 0.21 11.8 0.6 1.7 1 0 0 1 1 1 0 Fragile X-related 1 protein C-terminal region 2 DUF2516 PF10724.9 CCC68923.1 - 0.53 10.6 0.0 0.53 10.6 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF2516) CASP_C PF08172.12 CCC68924.1 - 1.5e-68 230.9 5.9 1.5e-68 230.9 5.9 5.0 2 1 2 4 4 4 1 CASP C terminal DUF4200 PF13863.6 CCC68924.1 - 0.0078 16.6 14.5 0.0078 16.6 14.5 6.7 5 1 0 5 5 5 2 Domain of unknown function (DUF4200) GNT-I PF03071.15 CCC68924.1 - 0.35 9.6 5.5 1.8 7.3 0.0 3.2 2 1 1 3 3 3 0 GNT-I family YojJ PF10372.9 CCC68924.1 - 0.71 10.0 10.9 0.15 12.2 0.3 3.7 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus Leu_zip PF15294.6 CCC68924.1 - 0.95 8.9 75.6 0.38 10.2 15.2 5.4 3 1 1 5 5 5 0 Leucine zipper Ribosomal_L22 PF00237.19 CCC68925.1 - 1e-37 128.5 1.4 1.2e-37 128.3 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e CRT10 PF08728.10 CCC68925.1 - 0.077 11.2 0.2 0.085 11.0 0.2 1.0 1 0 0 1 1 1 0 CRT10 MFS_1 PF07690.16 CCC68927.1 - 2.4e-26 92.5 17.1 2.9e-26 92.2 16.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3792 PF12670.7 CCC68927.1 - 0.11 12.6 7.7 0.03 14.5 1.8 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) SSB PF00436.25 CCC68928.1 - 5.6e-19 68.1 0.0 6.7e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Mannosyl_trans3 PF11051.8 CCC68929.1 - 5.7e-81 271.9 0.0 8.3e-81 271.3 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative YxiJ PF14176.6 CCC68929.1 - 0.82 10.2 4.5 0.29 11.6 0.5 2.3 3 0 0 3 3 3 0 YxiJ-like protein Ribosomal_L39 PF00832.20 CCC68930.1 - 3.1e-23 81.1 11.8 3.7e-23 80.9 11.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Ribosomal_S11 PF00411.19 CCC68931.1 - 4.7e-46 155.7 1.8 5.9e-46 155.4 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 CCC68931.1 - 0.044 13.1 0.4 0.055 12.8 0.4 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme NFACT-R_1 PF05670.13 CCC68931.1 - 0.12 13.0 0.0 0.16 12.7 0.0 1.1 1 0 0 1 1 1 0 NFACT protein RNA binding domain Beach PF02138.18 CCC68932.1 - 5.2e-119 396.7 0.1 9.7e-119 395.8 0.1 1.5 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 CCC68932.1 - 3.9e-10 39.7 0.0 1.8e-09 37.6 0.0 2.3 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH SPACA7 PF15307.6 CCC68932.1 - 0.0099 16.1 0.3 0.053 13.8 0.2 2.3 2 0 0 2 2 2 1 Sperm acrosome-associated protein 7 Laminin_G_3 PF13385.6 CCC68932.1 - 0.058 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Mad3_BUB1_I PF08311.12 CCC68932.1 - 0.31 11.0 2.7 1.6 8.7 0.0 3.2 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 Myb_DNA-binding PF00249.31 CCC68933.1 - 2.8e-15 56.2 0.0 2e-06 27.9 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCC68933.1 - 3.8e-07 30.3 0.1 0.022 15.0 0.1 3.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 CCC68933.1 - 0.038 13.9 8.7 0.045 13.6 0.1 3.3 2 0 0 2 2 2 0 Myb DNA-binding like Epimerase PF01370.21 CCC68933.1 - 0.16 11.4 0.2 0.32 10.4 0.2 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family ELO PF01151.18 CCC68934.1 - 1.1e-61 208.5 22.4 1.4e-61 208.2 22.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family RNase_PH PF01138.21 CCC68935.1 - 9.4e-25 87.6 1.0 4.3e-24 85.5 0.3 2.3 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 PfkB PF00294.24 CCC68936.1 - 7.9e-48 163.3 0.4 1.1e-46 159.5 0.4 2.0 1 1 0 1 1 1 1 pfkB family carbohydrate kinase MoCF_biosynth PF00994.24 CCC68936.1 - 0.029 14.0 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Probable molybdopterin binding domain DUF3369 PF11849.8 CCC68936.1 - 0.034 14.3 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) NuA4 PF09340.10 CCC68936.1 - 0.037 13.9 0.2 0.088 12.7 0.2 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 AAA_24 PF13479.6 CCC68936.1 - 0.098 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain SPX PF03105.19 CCC68937.1 - 7.4e-46 157.8 20.3 1.2e-45 157.1 20.3 1.4 1 0 0 1 1 1 1 SPX domain CitMHS PF03600.16 CCC68937.1 - 7.6e-25 87.7 64.8 8.7e-23 81.0 37.9 2.1 1 1 1 2 2 2 2 Citrate transporter RasGEF PF00617.19 CCC68938.1 - 1.6e-42 145.7 0.8 1.6e-42 145.7 0.8 2.9 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 CCC68938.1 - 1.8e-16 60.3 4.2 1.7e-15 57.2 0.5 3.5 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.28 CCC68938.1 - 0.005 16.4 0.1 0.011 15.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain RNase_H2_suC PF08615.11 CCC68939.1 - 4.4e-06 26.9 1.1 0.00076 19.7 0.2 2.0 1 1 1 2 2 2 2 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Homeodomain PF00046.29 CCC68940.1 - 3.3e-12 46.1 1.4 5.3e-12 45.4 1.4 1.4 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CCC68940.1 - 9e-06 25.5 0.2 9e-06 25.5 0.2 1.7 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.8 CCC68940.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_28 PF13518.6 CCC68940.1 - 0.051 13.7 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain AA_permease PF00324.21 CCC68942.1 - 5.2e-128 427.6 30.1 6e-128 427.4 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC68942.1 - 5.1e-32 111.2 30.2 6.2e-32 111.0 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease Colicin_im PF03857.13 CCC68942.1 - 1 9.3 6.3 0.1 12.6 0.8 2.1 2 0 0 2 2 2 0 Colicin immunity protein Rad60-SLD PF11976.8 CCC68943.1 - 5.3e-18 64.6 0.8 6.5e-18 64.3 0.1 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CCC68943.1 - 1.9e-12 46.7 0.0 2.4e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.25 CCC68944.1 - 6.1e-71 238.9 0.0 1.8e-70 237.3 0.0 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC68944.1 - 4.7e-35 121.1 0.0 1.5e-34 119.5 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Fungal_KA1 PF16797.5 CCC68944.1 - 1.4e-33 115.1 2.8 3.6e-33 113.8 2.8 1.8 1 0 0 1 1 1 1 Fungal kinase associated-1 domain Kinase-like PF14531.6 CCC68944.1 - 2.2e-06 27.2 1.9 1.7e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CCC68944.1 - 3.5 7.5 4.4 0.51 10.2 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family PSP1 PF04468.12 CCC68945.1 - 1.8e-42 143.5 0.2 7.7e-42 141.5 0.1 2.2 2 0 0 2 2 2 1 PSP1 C-terminal conserved region PBP PF01161.20 CCC68946.1 - 1.2e-17 64.5 0.1 1.6e-17 64.1 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.20 CCC68947.1 - 8.1e-21 74.7 0.0 9.9e-21 74.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Vta1 PF04652.16 CCC68948.1 - 5.9e-38 130.1 0.1 5.9e-38 130.1 0.1 2.4 2 1 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 CCC68948.1 - 2.8e-14 52.5 0.4 8.6e-14 50.9 0.1 2.1 2 0 0 2 2 2 1 Vta1 C-terminal domain S-AdoMet_synt_C PF02773.16 CCC68949.1 - 5.9e-65 217.4 0.1 1.1e-64 216.5 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_N PF00438.20 CCC68949.1 - 1.3e-45 154.1 1.5 1.9e-45 153.6 0.2 1.8 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain S-AdoMet_synt_M PF02772.16 CCC68949.1 - 9.5e-45 151.7 0.0 2.2e-44 150.6 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain AdoMet_Synthase PF01941.19 CCC68949.1 - 0.014 14.2 0.4 0.16 10.7 0.1 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Lactamase_B_3 PF13483.6 CCC68949.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Swi6_N PF18530.1 CCC68950.1 - 2.5e-41 140.2 0.4 2.5e-41 140.2 0.4 3.3 4 0 0 4 4 3 1 Swi6 N-terminal domain Ank_5 PF13857.6 CCC68950.1 - 2.1e-11 43.8 3.1 3.1e-05 24.1 0.2 3.0 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCC68950.1 - 2.9e-10 40.6 0.5 0.0021 18.6 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCC68950.1 - 1e-09 37.8 0.6 0.00018 21.7 0.1 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 CCC68950.1 - 5.2e-09 36.5 0.5 0.00024 21.6 0.0 4.2 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 CCC68950.1 - 1.1e-06 28.8 3.4 0.017 15.6 0.1 3.2 3 0 0 3 3 2 2 Ankyrin repeat Phage_GPO PF05929.11 CCC68950.1 - 0.37 10.4 8.9 0.052 13.2 4.6 1.7 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase TEX13 PF15186.6 CCC68950.1 - 0.47 10.1 8.1 0.35 10.5 0.5 2.6 2 0 0 2 2 2 0 Testis-expressed sequence 13 protein family Myb_DNA-bind_3 PF12776.7 CCC68950.1 - 0.78 10.8 3.5 1.2 10.2 0.7 2.8 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain DUF3837 PF12939.7 CCC68950.1 - 0.97 9.9 6.2 1.3 9.5 3.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) OmpH PF03938.14 CCC68950.1 - 1 9.7 19.0 1.2 9.5 9.2 3.3 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) FAM76 PF16046.5 CCC68950.1 - 1.2 8.4 14.3 0.1 12.0 7.2 2.2 2 0 0 2 2 2 0 FAM76 protein SesA PF17107.5 CCC68950.1 - 2.3 8.4 7.8 9 6.5 0.1 3.2 3 1 1 4 4 3 0 N-terminal domain on NACHT_NTPase and P-loop NTPases AKNA PF12443.8 CCC68950.1 - 2.6 8.7 8.0 27 5.5 1.1 2.9 1 1 1 2 2 2 0 AT-hook-containing transcription factor HIP1_clath_bdg PF16515.5 CCC68950.1 - 3.1 8.5 20.6 0.093 13.4 9.0 3.4 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Spc7 PF08317.11 CCC68950.1 - 3.7 6.3 20.5 0.32 9.8 9.3 2.9 3 0 0 3 3 3 0 Spc7 kinetochore protein FHA PF00498.26 CCC68951.1 - 5.7e-09 36.2 0.0 1.7e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 FHA domain Polysacc_deac_3 PF15421.6 CCC68951.1 - 0.043 12.3 0.0 0.079 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative polysaccharide deacetylase TMPIT PF07851.13 CCC68951.1 - 0.44 9.7 4.4 0.86 8.8 4.4 1.4 1 0 0 1 1 1 0 TMPIT-like protein Ribosomal_L37e PF01907.19 CCC68952.1 - 1.6e-27 95.4 10.8 2.8e-27 94.6 10.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 CCC68952.1 - 0.002 18.1 1.4 0.0027 17.7 1.4 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 CCC68952.1 - 0.01 15.9 0.7 0.012 15.7 0.7 1.3 1 0 0 1 1 1 0 SelR domain zf-RING_5 PF14634.6 CCC68952.1 - 0.033 14.2 3.3 0.05 13.6 3.3 1.3 1 0 0 1 1 1 0 zinc-RING finger domain GATA PF00320.27 CCC68952.1 - 0.079 12.6 5.6 0.76 9.4 1.1 2.5 1 1 1 2 2 2 0 GATA zinc finger DUF1258 PF06869.12 CCC68952.1 - 0.29 10.6 4.5 0.18 11.3 3.1 1.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) zinc_ribbon_2 PF13240.6 CCC68952.1 - 0.69 9.7 5.5 9.4 6.1 1.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain PH PF00169.29 CCC68953.1 - 1.4e-06 28.7 0.1 0.0001 22.8 0.0 2.8 2 0 0 2 2 2 1 PH domain IQCJ-SCHIP1 PF15157.6 CCC68953.1 - 2.9 7.7 8.7 0.11 12.3 0.6 2.7 3 0 0 3 3 3 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif ABC_membrane PF00664.23 CCC68954.1 - 2.8e-63 214.2 6.3 3.6e-63 213.8 6.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CCC68954.1 - 2.5e-32 112.2 0.0 6.5e-32 110.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CCC68954.1 - 6.2e-08 32.3 0.3 6.6e-05 22.4 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CCC68954.1 - 0.00042 20.6 0.2 0.0043 17.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCC68954.1 - 0.0018 18.7 0.1 0.0052 17.2 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CCC68954.1 - 0.0019 18.8 0.0 0.042 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 CCC68954.1 - 0.0032 17.2 0.1 0.01 15.5 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCC68954.1 - 0.0075 16.2 0.0 0.033 14.1 0.0 2.1 1 0 0 1 1 1 1 RsgA GTPase AAA_33 PF13671.6 CCC68954.1 - 0.022 14.9 0.0 0.22 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.14 CCC68954.1 - 0.023 14.7 0.0 0.093 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.12 CCC68954.1 - 0.026 13.8 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 CCC68954.1 - 0.029 14.1 0.1 3.9 7.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF87 PF01935.17 CCC68954.1 - 0.029 14.4 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_7 PF12775.7 CCC68954.1 - 0.037 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region 6PF2K PF01591.18 CCC68954.1 - 0.041 13.2 0.0 0.075 12.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA PF00004.29 CCC68954.1 - 0.08 13.4 0.3 3.1 8.2 0.0 3.4 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 CCC68954.1 - 0.1 12.4 0.0 1.8 8.3 0.0 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_21 PF13304.6 CCC68954.1 - 0.11 12.3 0.2 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system APS_kinase PF01583.20 CCC68954.1 - 0.15 12.0 0.1 0.54 10.2 0.0 2.0 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_24 PF13479.6 CCC68954.1 - 0.16 11.6 0.0 0.35 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PrgI PF12666.7 CCC68954.1 - 2.8 8.7 6.8 3.8 8.3 0.0 3.0 3 0 0 3 3 2 0 PrgI family protein Glyco_transf_28 PF03033.20 CCC68955.1 - 4.9e-30 104.4 0.0 1.7e-29 102.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.20 CCC68955.1 - 1.6e-24 86.0 5.0 4e-18 65.3 0.2 3.6 2 1 0 2 2 2 2 GRAM domain UDPGT PF00201.18 CCC68955.1 - 4e-08 32.5 0.0 8.6e-08 31.4 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.29 CCC68955.1 - 1.6e-05 25.3 3.7 2e-05 25.1 0.2 2.9 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 CCC68955.1 - 0.077 13.4 1.4 0.22 12.0 0.1 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Exo_endo_phos PF03372.23 CCC68956.1 - 8.2e-16 58.2 0.0 1.1e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4231 PF14015.6 CCC68956.1 - 0.014 15.9 0.9 0.031 14.8 0.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) DUF2207 PF09972.9 CCC68956.1 - 0.091 11.5 0.4 0.12 11.1 0.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2304 PF10066.9 CCC68956.1 - 0.46 10.7 6.6 0.9 9.8 6.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) S_4TM PF18159.1 CCC68956.1 - 0.61 9.3 4.0 1.1 8.4 4.0 1.3 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain Spindle_Spc25 PF08234.12 CCC68957.1 - 1.8e-18 66.5 0.1 4.7e-18 65.2 0.1 1.8 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 phiKZ_IP PF12699.7 CCC68957.1 - 0.0054 15.9 3.3 0.0068 15.6 3.3 1.2 1 0 0 1 1 1 1 phiKZ-like phage internal head proteins JIP_LZII PF16471.5 CCC68957.1 - 0.015 15.5 3.3 0.015 15.5 3.3 2.9 1 1 2 3 3 3 0 JNK-interacting protein leucine zipper II Seryl_tRNA_N PF02403.22 CCC68957.1 - 0.016 15.4 2.7 0.016 15.4 2.7 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 CCC68957.1 - 0.019 15.2 17.1 0.11 12.8 2.7 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Circo_capsid PF02443.15 CCC68957.1 - 0.078 12.6 0.4 0.1 12.1 0.4 1.2 1 0 0 1 1 1 0 Circovirus capsid protein Laminin_II PF06009.12 CCC68957.1 - 0.16 12.0 7.9 0.045 13.8 2.7 2.1 1 1 1 2 2 2 0 Laminin Domain II GAS PF13851.6 CCC68957.1 - 0.28 10.5 22.2 0.023 14.0 6.9 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 CCC68957.1 - 0.28 11.2 17.5 0.89 9.6 1.4 3.2 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Filament PF00038.21 CCC68957.1 - 0.51 9.9 19.5 2 7.9 19.0 1.8 1 1 0 1 1 1 0 Intermediate filament protein CENP-F_leu_zip PF10473.9 CCC68957.1 - 0.62 10.1 20.6 0.33 11.0 10.9 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cep57_CLD_2 PF14197.6 CCC68957.1 - 0.64 10.1 10.2 5 7.3 0.3 3.0 2 2 0 2 2 2 0 Centrosome localisation domain of PPC89 Spc24 PF08286.11 CCC68957.1 - 0.67 10.2 16.2 0.069 13.4 3.7 2.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 APG6_N PF17675.1 CCC68957.1 - 1.1 9.8 22.2 6.5 7.3 22.2 2.0 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4407 PF14362.6 CCC68957.1 - 1.1 8.5 6.8 1.5 8.1 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 CCC68957.1 - 1.4 7.8 18.8 3.6 6.4 18.9 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DASH_Dad3 PF08656.10 CCC68957.1 - 1.4 9.0 8.1 1.1e+02 3.0 8.1 2.9 1 1 0 1 1 1 0 DASH complex subunit Dad3 Snapin_Pallidin PF14712.6 CCC68957.1 - 1.4 9.4 17.6 1.2 9.5 2.4 2.5 1 1 0 2 2 2 0 Snapin/Pallidin UPF0242 PF06785.11 CCC68957.1 - 2.5 8.2 21.1 5 7.2 21.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF1090 PF06476.12 CCC68957.1 - 2.9 8.1 10.8 6.4 6.9 10.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Exonuc_VII_L PF02601.15 CCC68957.1 - 3.9 7.0 13.5 5.4 6.5 13.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 CCC68957.1 - 8 4.2 12.9 9.4 4.0 12.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup54 PF13874.6 CCC68957.1 - 9.4 6.3 13.3 97 3.1 13.3 2.2 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Per1 PF04080.13 CCC68958.1 - 1.5e-84 283.7 21.0 1.9e-84 283.4 21.0 1.1 1 0 0 1 1 1 1 Per1-like family DUF1230 PF06799.11 CCC68958.1 - 2.4 8.3 6.6 0.33 11.1 1.7 1.9 2 0 0 2 2 2 0 Conserved in the green lineage and diatoms 27 Nitroreductase PF00881.24 CCC68960.1 - 0.00017 21.7 0.1 0.00045 20.3 0.1 1.6 1 1 0 1 1 1 1 Nitroreductase family Nitroreductase PF00881.24 CCC68961.1 - 6e-06 26.4 0.1 9.5e-06 25.8 0.1 1.3 1 1 0 1 1 1 1 Nitroreductase family Nitroreductase PF00881.24 CCC68962.1 - 1.9e-09 37.8 0.1 3.1e-09 37.1 0.1 1.4 1 1 0 1 1 1 1 Nitroreductase family SH3_9 PF14604.6 CCC68963.1 - 0.00018 21.3 0.0 0.00057 19.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SKG6 PF08693.10 CCC68963.1 - 0.029 13.8 0.0 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain SH3_1 PF00018.28 CCC68963.1 - 0.032 13.9 0.3 0.091 12.4 0.0 2.0 2 0 0 2 2 2 0 SH3 domain SH3_2 PF07653.17 CCC68963.1 - 0.18 11.5 0.1 0.4 10.4 0.1 1.6 1 1 0 1 1 1 0 Variant SH3 domain Dapper PF15268.6 CCC68964.1 - 0.00072 18.6 42.1 0.00085 18.3 42.1 1.2 1 0 0 1 1 1 1 Dapper CAP_GLY PF01302.25 CCC68965.1 - 9.2e-17 60.8 0.7 3.9e-16 58.8 0.2 2.0 2 0 0 2 2 2 1 CAP-Gly domain CLIP1_ZNF PF16641.5 CCC68965.1 - 4.7e-05 23.1 1.4 7.5e-05 22.5 1.4 1.3 1 0 0 1 1 1 1 CLIP1 zinc knuckle Fez1 PF06818.15 CCC68965.1 - 0.01 16.3 37.6 0.2 12.1 12.1 2.2 1 1 1 2 2 2 0 Fez1 End3 PF12761.7 CCC68965.1 - 0.3 11.2 35.4 0.15 12.3 9.7 2.9 1 1 1 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 Allexi_40kDa PF05549.11 CCC68965.1 - 1.4 8.4 23.1 0.19 11.2 4.0 2.7 1 1 1 3 3 3 0 Allexivirus 40kDa protein DUF948 PF06103.11 CCC68965.1 - 4.1 7.7 8.9 23 5.3 0.5 3.1 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 CCC68965.1 - 4.7 6.0 34.5 1.7 7.5 12.7 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein CorA PF01544.18 CCC68965.1 - 8.5 5.6 18.8 2.9 7.1 2.7 2.8 2 1 1 3 3 3 0 CorA-like Mg2+ transporter protein YlqD PF11068.8 CCC68965.1 - 10 6.5 34.0 3.8 7.9 13.1 2.8 1 1 2 3 3 3 0 YlqD protein Histidinol_dh PF00815.20 CCC68966.1 - 1.7e-159 531.2 0.6 2.7e-159 530.6 0.6 1.3 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.18 CCC68966.1 - 8.2e-27 92.8 0.1 1.9e-26 91.7 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 CCC68966.1 - 5.2e-13 49.2 1.0 1.1e-12 48.2 1.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase RRM_Rrp7 PF17799.1 CCC68967.1 - 4.7e-43 146.8 3.4 1.1e-42 145.6 3.4 1.6 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain RRP7 PF12923.7 CCC68967.1 - 1.9e-24 86.0 11.4 1.9e-24 86.0 11.4 1.7 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF45 PF01863.17 CCC68967.1 - 0.099 12.7 3.9 0.18 11.8 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 SAM_Ste50p PF09235.10 CCC68968.1 - 7.2e-28 96.6 3.5 2.1e-27 95.2 3.5 1.8 1 0 0 1 1 1 1 Ste50p, sterile alpha motif RA PF00788.23 CCC68968.1 - 3.1e-15 56.6 0.0 6.8e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SelR PF01641.18 CCC68969.1 - 8.7e-49 164.6 0.7 1.1e-48 164.3 0.7 1.1 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 CCC68969.1 - 0.0086 15.8 0.9 2 8.2 0.0 2.3 2 0 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein TF_Zn_Ribbon PF08271.12 CCC68969.1 - 0.015 14.8 1.0 0.55 9.8 0.1 2.4 2 0 0 2 2 2 0 TFIIB zinc-binding Ribosomal_L37e PF01907.19 CCC68969.1 - 0.017 15.3 4.2 0.056 13.6 0.4 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e GFA PF04828.14 CCC68969.1 - 0.026 14.9 1.5 2 8.8 0.1 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.7 CCC68969.1 - 0.074 13.1 4.3 0.62 10.1 0.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon zf-ACC PF17848.1 CCC68969.1 - 0.082 13.0 2.7 1.3 9.2 0.2 3.2 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain HypA PF01155.19 CCC68969.1 - 0.098 12.7 0.7 0.24 11.4 0.7 1.6 1 1 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TFIIS_C PF01096.18 CCC68969.1 - 0.11 12.4 1.5 4.1 7.3 0.2 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-LITAF-like PF10601.9 CCC68969.1 - 0.3 11.4 2.2 3.7 7.9 0.2 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-Mss51 PF13824.6 CCC68969.1 - 0.31 11.2 4.7 2 8.6 0.3 2.9 1 1 2 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_RNApol_7kD PF03604.13 CCC68969.1 - 0.33 10.7 3.7 14 5.4 0.4 3.2 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc_ribbon_2 PF13240.6 CCC68969.1 - 0.86 9.4 5.6 8.2 6.3 1.5 2.6 2 1 0 2 2 2 0 zinc-ribbon domain Zn_ribbon_SprT PF17283.2 CCC68969.1 - 2.3 8.2 5.6 32 4.6 5.6 2.2 1 1 0 1 1 1 0 SprT-like zinc ribbon domain GAT PF03127.14 CCC68970.1 - 0.0017 18.6 0.5 0.0066 16.7 0.0 2.2 3 0 0 3 3 3 1 GAT domain VHS PF00790.19 CCC68970.1 - 0.0042 17.0 0.6 0.01 15.7 0.6 1.7 1 1 0 1 1 1 1 VHS domain Glutaredoxin PF00462.24 CCC68971.1 - 8.9e-15 54.7 0.0 1.4e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 CCC68971.1 - 0.00037 20.5 0.1 0.00057 19.9 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_4 PF13462.6 CCC68971.1 - 0.0058 16.8 0.5 0.015 15.5 0.5 1.6 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 CCC68971.1 - 0.12 12.9 0.2 0.14 12.6 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.20 CCC68971.1 - 0.16 11.7 0.1 0.84 9.4 0.1 1.9 1 1 0 1 1 1 0 DSBA-like thioredoxin domain Coilin_N PF15862.5 CCC68972.1 - 0.00012 21.8 1.8 0.00012 21.8 1.8 2.9 2 1 0 2 2 2 1 Coilin N-terminus DDHD PF02862.17 CCC68972.1 - 0.0027 17.9 7.6 0.17 12.1 0.1 2.4 2 1 0 2 2 2 2 DDHD domain RNA_pol_Rpc4 PF05132.14 CCC68972.1 - 0.0057 17.1 1.2 0.0057 17.1 1.2 2.4 2 0 0 2 2 2 1 RNA polymerase III RPC4 Connexin PF00029.19 CCC68972.1 - 0.012 15.4 3.2 0.012 15.4 3.2 2.5 3 0 0 3 3 3 0 Connexin Vfa1 PF08432.10 CCC68972.1 - 0.012 15.9 8.4 0.012 15.9 8.4 3.0 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 NPR3 PF03666.13 CCC68972.1 - 0.073 11.9 12.1 0.081 11.7 2.6 2.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 RP-C_C PF11800.8 CCC68972.1 - 0.28 11.3 7.7 0.19 11.8 0.3 2.6 2 0 0 2 2 2 0 Replication protein C C-terminal region CPSF100_C PF13299.6 CCC68972.1 - 0.48 10.6 16.7 0.39 10.9 4.7 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Ctr PF04145.15 CCC68972.1 - 1 10.0 4.6 12 6.5 1.3 2.6 2 0 0 2 2 2 0 Ctr copper transporter family OATP PF03137.20 CCC68972.1 - 1.1 7.4 5.0 0.74 8.0 0.5 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family PPL5 PF18168.1 CCC68972.1 - 1.2 8.4 18.5 0.065 12.5 5.5 2.4 2 0 0 2 2 2 0 Prim-pol family 5 SET PF00856.28 CCC68972.1 - 1.6 9.1 7.9 0.76 10.1 2.1 2.5 2 1 0 3 3 3 0 SET domain RAB3GAP2_C PF14656.6 CCC68972.1 - 4.8 5.3 10.6 2.6 6.2 1.9 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF913 PF06025.12 CCC68972.1 - 4.9 6.0 10.1 6.2 5.7 1.0 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) EOS1 PF12326.8 CCC68972.1 - 5.6 6.9 4.9 2.3 8.1 0.9 2.1 2 0 0 2 2 2 0 N-glycosylation protein Eapp_C PF10238.9 CCC68972.1 - 6.4 6.8 14.7 2.5 8.2 4.2 2.6 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF1980 PF09323.10 CCC68972.1 - 9.3 6.1 10.2 6.1 6.7 2.6 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1980) La PF05383.17 CCC68973.1 - 2.1e-16 59.7 0.3 8.6e-16 57.7 0.0 2.2 3 0 0 3 3 3 1 La domain Hid1 PF12722.7 CCC68973.1 - 0.0018 16.5 18.5 0.0018 16.5 18.5 2.4 2 1 1 3 3 3 1 High-temperature-induced dauer-formation protein LMBR1 PF04791.16 CCC68973.1 - 6.1 5.6 8.8 0.41 9.5 3.6 1.6 2 0 0 2 2 2 0 LMBR1-like membrane protein ATG22 PF11700.8 CCC68974.1 - 1.6e-157 525.0 17.8 1.8e-157 524.8 17.8 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.16 CCC68974.1 - 3.1e-08 33.0 32.4 4.9e-08 32.3 15.6 3.1 2 2 1 3 3 3 3 Major Facilitator Superfamily WD40 PF00400.32 CCC68975.1 - 6.2e-16 58.5 6.3 0.0078 17.1 0.0 6.3 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC68975.1 - 2.6e-10 40.5 0.0 0.061 13.6 0.0 5.1 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF3950 PF13132.6 CCC68975.1 - 0.21 11.4 0.5 0.58 10.0 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) Hom_end PF05204.14 CCC68976.1 - 2e-14 53.7 0.0 2.6e-11 43.7 0.0 2.5 2 0 0 2 2 2 2 Homing endonuclease Hom_end_hint PF05203.16 CCC68976.1 - 1.7e-10 41.2 0.0 5.2e-09 36.4 0.0 2.4 1 1 0 1 1 1 1 Hom_end-associated Hint AXH PF08517.12 CCC68976.1 - 0.058 13.9 0.0 0.17 12.5 0.0 1.8 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) Hexokinase_2 PF03727.16 CCC68977.1 - 3.5e-79 265.6 0.0 4.9e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCC68977.1 - 5.5e-73 245.1 0.0 1.1e-72 244.1 0.0 1.5 2 0 0 2 2 2 1 Hexokinase Thioredoxin PF00085.20 CCC68978.1 - 7.5e-59 196.1 2.6 2e-31 108.0 0.2 3.4 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 CCC68978.1 - 8.1e-26 91.1 8.5 4e-21 75.8 0.3 4.1 4 1 1 5 5 5 2 Thioredoxin-like domain OST3_OST6 PF04756.13 CCC68978.1 - 9.3e-10 38.3 0.1 0.00011 21.6 0.0 2.4 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 CCC68978.1 - 1.1e-06 28.7 0.0 0.013 15.6 0.0 2.9 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.6 CCC68978.1 - 5.4e-06 26.7 0.8 0.61 10.4 0.0 4.2 3 2 2 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.21 CCC68978.1 - 6.6e-06 26.1 0.5 0.017 15.1 0.1 3.3 3 1 1 4 4 4 2 AhpC/TSA family Thioredoxin_2 PF13098.6 CCC68978.1 - 7.6e-06 26.3 2.2 0.025 15.0 0.1 3.4 2 2 1 3 3 3 2 Thioredoxin-like domain Redoxin PF08534.10 CCC68978.1 - 0.00045 19.9 1.7 0.14 11.9 0.0 2.9 3 0 0 3 3 3 2 Redoxin DUF5047 PF16466.5 CCC68978.1 - 0.023 15.0 0.0 0.056 13.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5047) TraF PF13728.6 CCC68978.1 - 0.067 13.0 0.5 0.71 9.6 0.0 2.7 3 0 0 3 3 3 0 F plasmid transfer operon protein Thioredoxin_5 PF13743.6 CCC68978.1 - 0.086 12.5 1.0 1.8 8.2 0.0 3.2 2 2 1 3 3 3 0 Thioredoxin DUF1539 PF07560.11 CCC68978.1 - 0.093 12.8 0.1 0.2 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Thioredoxin_4 PF13462.6 CCC68978.1 - 4.4 7.4 8.2 8.2 6.5 0.3 3.9 3 2 1 4 4 4 0 Thioredoxin Mgr1 PF08602.10 CCC68979.1 - 3.2e-175 582.6 0.3 3.7e-175 582.4 0.3 1.0 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit EMC1_C PF07774.13 CCC68980.1 - 3.6e-64 216.4 0.2 6.4e-64 215.5 0.2 1.4 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 CCC68980.1 - 0.0025 17.4 0.0 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 PQQ-like domain CTP_transf_like PF01467.26 CCC68981.1 - 1.4e-05 25.3 0.0 2.6e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like OST_P2 PF18235.1 CCC68981.1 - 0.037 14.0 0.0 4.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Oligosaccharyltransferase Peripheral 2 domain ATP-sulfurylase PF01747.17 CCC68981.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP-sulfurylase QCR10 PF09796.9 CCC68983.1 - 5.3 7.2 7.0 1.8 8.7 3.2 1.9 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) ATP_transf PF09830.9 CCC68984.1 - 1.3e-16 60.5 0.0 2.1e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4931 PF16285.5 CCC68984.1 - 5.3e-05 22.6 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4931) DUF4922 PF16269.5 CCC68984.1 - 0.00054 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) HIT PF01230.23 CCC68984.1 - 0.14 12.9 0.0 0.34 11.7 0.0 1.6 1 0 0 1 1 1 0 HIT domain PIG-X PF08320.12 CCC68986.1 - 6.8e-33 114.4 0.5 1.1e-32 113.7 0.5 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 Spb1_C PF07780.12 CCC68987.1 - 2e-83 279.2 28.0 2e-83 279.2 28.0 3.1 3 1 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.19 CCC68987.1 - 1.4e-53 181.7 0.1 2.8e-53 180.7 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 CCC68987.1 - 8.1e-44 149.3 21.5 8.1e-44 149.3 21.5 6.0 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) MT-A70 PF05063.14 CCC68988.1 - 8e-13 48.7 0.1 1.2e-12 48.1 0.1 1.2 1 0 0 1 1 1 1 MT-A70 CaM-KIIN PF15170.6 CCC68989.1 - 0.13 12.4 4.7 13 6.0 0.2 3.7 2 1 2 4 4 4 0 Calcium/calmodulin-dependent protein kinase II inhibitor DUF5110 PF17137.4 CCC68989.1 - 1.2 9.5 6.6 0.57 10.5 1.5 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF5110) Peptidase_M3 PF01432.20 CCC68991.1 - 1e-145 486.5 2.0 1.6e-145 485.9 2.0 1.3 1 0 0 1 1 1 1 Peptidase family M3 DUF543 PF04418.12 CCC68992.1 - 1.4e-31 108.3 0.0 1.6e-31 108.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) PEP-utilisers_N PF05524.13 CCC68993.1 - 0.075 13.2 0.2 0.088 13.0 0.2 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Protamine_3 PF08188.11 CCC68993.1 - 0.47 10.7 13.3 0.24 11.6 7.9 2.6 2 1 0 2 2 2 0 Spermatozal protamine family KH_8 PF17903.1 CCC68994.1 - 3.8e-32 110.2 0.0 1.1e-31 108.7 0.0 1.8 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 CCC68994.1 - 0.0053 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 KH domain MRC1 PF09444.10 CCC68995.1 - 1e-42 146.1 11.8 1e-42 146.1 11.8 7.2 3 1 4 8 8 8 1 MRC1-like domain DGF-1_C PF11040.8 CCC68995.1 - 0.18 11.8 8.8 0.034 14.1 2.5 3.2 3 0 0 3 3 3 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus Vac17 PF17321.2 CCC68996.1 - 2.4e-95 320.6 40.8 4.3e-95 319.8 40.8 1.4 1 1 0 1 1 1 1 Vacuole-related protein 17 V_ATPase_I PF01496.19 CCC68996.1 - 0.072 11.0 8.8 0.11 10.4 8.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PALP PF00291.25 CCC68997.1 - 2.9e-63 214.0 0.0 3.2e-63 213.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peripla_BP_4 PF13407.6 CCC68997.1 - 0.044 13.3 0.1 0.1 12.2 0.0 1.6 2 0 0 2 2 2 0 Periplasmic binding protein domain Homeobox_KN PF05920.11 CCC68998.1 - 1.4e-08 34.5 0.3 3.2e-08 33.3 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CCC68998.1 - 1.2e-06 28.2 0.7 1.2e-06 28.2 0.7 2.2 2 1 0 2 2 2 1 Homeodomain Homez PF11569.8 CCC68998.1 - 0.077 12.5 0.3 0.15 11.5 0.3 1.5 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez MATalpha_HMGbox PF04769.12 CCC68999.1 - 3.6e-12 46.0 0.2 4.6e-12 45.7 0.2 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 HMG-box Sir1 PF11603.8 CCC69001.1 - 7.5e-37 126.5 0.2 4.2e-36 124.0 0.1 2.1 2 0 0 2 2 2 1 Regulatory protein Sir1 DUF5341 PF17276.2 CCC69002.1 - 7.2e-12 45.8 0.6 7.4e-12 45.7 0.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5341) ALO PF04030.14 CCC69003.1 - 6.3e-95 317.9 2.3 8.8e-95 317.4 2.3 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 CCC69003.1 - 1.4e-27 96.1 0.1 2e-27 95.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 CCC69003.1 - 0.038 14.1 0.2 0.1 12.7 0.2 1.8 1 0 0 1 1 1 0 Berberine and berberine like SIS_2 PF13580.6 CCC69003.1 - 0.095 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 SIS domain UPF0180 PF03698.13 CCC69003.1 - 0.14 12.4 0.3 0.39 10.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0180) F-box-like PF12937.7 CCC69004.1 - 7.3e-09 35.4 0.1 1.4e-08 34.5 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CCC69004.1 - 9.8e-07 28.5 0.4 2.4e-06 27.3 0.4 1.7 1 0 0 1 1 1 1 F-box domain UIM PF02809.20 CCC69004.1 - 0.0034 17.2 18.4 0.012 15.5 4.3 4.9 4 0 0 4 4 4 2 Ubiquitin interaction motif PRANC PF09372.10 CCC69004.1 - 0.013 15.8 0.5 0.13 12.6 0.1 2.9 2 0 0 2 2 2 0 PRANC domain FTH PF01827.27 CCC69004.1 - 0.015 15.1 0.0 0.072 12.9 0.0 2.2 1 1 0 1 1 1 0 FTH domain F-box_4 PF15966.5 CCC69004.1 - 0.17 11.8 2.7 0.16 11.8 0.2 2.2 2 1 0 2 2 2 0 F-box Na_trans_assoc PF06512.13 CCC69004.1 - 0.98 9.7 9.7 1.8 8.8 9.7 1.4 1 0 0 1 1 1 0 Sodium ion transport-associated VGCC_beta4Aa_N PF12052.8 CCC69004.1 - 6.7 6.9 9.1 4.4 7.5 0.2 3.0 3 0 0 3 3 3 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal HMG_CoA_synt_C PF08540.10 CCC69005.1 - 7.3e-116 386.7 1.9 9.3e-116 386.3 1.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 CCC69005.1 - 2.5e-98 327.1 1.4 3.8e-98 326.5 0.7 1.6 2 0 0 2 2 2 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal RPM2 PF08579.11 CCC69006.1 - 4.9e-45 152.8 4.1 4.9e-45 152.8 4.1 3.8 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.6 CCC69006.1 - 6e-05 23.2 1.1 2.9 8.1 0.3 5.0 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 CCC69006.1 - 0.011 15.9 0.1 8.9 6.8 0.0 4.1 3 0 0 3 3 3 0 PPR repeat PPR_long PF17177.4 CCC69006.1 - 0.094 12.1 0.1 0.29 10.4 0.1 1.8 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP ATP-synt PF00231.19 CCC69006.1 - 5.7 6.6 8.5 35 4.0 0.0 4.0 3 1 1 4 4 4 0 ATP synthase Prefoldin PF02996.17 CCC69007.1 - 2.2e-25 88.9 2.3 2.8e-25 88.6 2.3 1.1 1 0 0 1 1 1 1 Prefoldin subunit PHM7_cyt PF14703.6 CCC69007.1 - 0.003 17.8 4.9 0.004 17.4 5.0 1.3 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter GIT_CC PF16559.5 CCC69007.1 - 0.016 15.1 0.8 7.3 6.5 0.0 2.5 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor E2F_CC-MB PF16421.5 CCC69007.1 - 0.072 13.5 0.7 0.072 13.5 0.7 2.2 1 1 0 2 2 2 0 E2F transcription factor CC-MB domain TSNAXIP1_N PF15739.5 CCC69007.1 - 0.55 10.6 8.6 9.9 6.6 0.1 2.2 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus Rad10 PF03834.14 CCC69008.1 - 7.8e-38 129.0 1.2 1.1e-37 128.6 1.2 1.2 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Inos-1-P_synth PF01658.17 CCC69008.1 - 0.046 14.0 0.1 0.088 13.1 0.1 1.5 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase Tropomodulin PF03250.14 CCC69008.1 - 0.1 12.6 0.7 0.2 11.7 0.7 1.4 1 0 0 1 1 1 0 Tropomodulin Asn_synthase PF00733.21 CCC69009.1 - 4.1e-21 76.0 0.0 3.6e-10 40.0 0.0 2.3 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CCC69009.1 - 7.6e-13 48.5 0.0 9.7e-11 41.6 0.0 2.9 1 1 1 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CCC69009.1 - 8.5e-07 29.2 0.0 3.4e-06 27.3 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CCC69009.1 - 0.024 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein VPS9 PF02204.18 CCC69010.1 - 2.6e-25 88.6 0.2 9.5e-25 86.8 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 CCC69010.1 - 2.8e-12 46.7 0.1 1e-11 45.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) CUE PF02845.16 CCC69010.1 - 9.9e-12 44.3 0.0 2e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 CUE domain ERO1 PF04137.15 CCC69011.1 - 3.3e-108 362.0 4.2 4.7e-108 361.5 4.2 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Fungal_trans_2 PF11951.8 CCC69012.1 - 4.7e-108 361.4 1.7 6.1e-108 361.1 1.7 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC69012.1 - 3.1e-11 43.2 6.1 3.1e-11 43.2 6.1 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2304 PF10066.9 CCC69012.1 - 0.038 14.2 0.0 0.09 13.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Ribonuclease_3 PF00636.26 CCC69013.1 - 9e-21 74.5 0.1 1.9e-19 70.2 0.0 2.8 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 CCC69013.1 - 4.8e-15 56.0 0.0 1.3e-07 32.3 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.6 CCC69013.1 - 6.3e-14 52.2 0.0 1.2e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like SRP1_TIP1 PF00660.17 CCC69014.1 - 5.5e-08 32.8 9.1 5.6e-05 23.1 0.2 4.0 3 1 0 3 3 3 2 Seripauperin and TIP1 family zf-CCHC PF00098.23 CCC69015.1 - 0.00029 20.8 2.9 0.00046 20.1 2.9 1.3 1 0 0 1 1 1 1 Zinc knuckle Tubulin PF00091.25 CCC69016.1 - 6.8e-66 222.2 0.0 9.9e-66 221.7 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCC69016.1 - 2.9e-50 169.7 0.1 4.4e-50 169.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Hydrolase_4 PF12146.8 CCC69016.1 - 0.17 11.1 0.0 0.38 10.0 0.0 1.6 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Sugar_tr PF00083.24 CCC69017.1 - 1.6e-46 159.2 17.0 2.7e-46 158.4 17.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC69017.1 - 4.5e-19 68.6 15.0 2.5e-11 43.1 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAM178 PF14816.6 CCC69017.1 - 0.041 12.9 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 SQS_PSY PF00494.19 CCC69018.1 - 5.6e-41 140.8 0.0 6.9e-41 140.5 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Pept_tRNA_hydro PF01195.19 CCC69019.1 - 2.6e-36 125.1 0.0 3.1e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase RNB PF00773.19 CCC69020.1 - 8.9e-66 222.4 1.7 1.7e-65 221.5 0.0 2.1 2 0 0 2 2 2 1 RNB domain Exo_endo_phos PF03372.23 CCC69021.1 - 8.2e-32 110.6 0.0 1.1e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RXT2_N PF08595.11 CCC69021.1 - 2.2 8.3 8.7 11 6.0 0.1 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal Ku_N PF03731.15 CCC69022.1 - 2.6e-34 118.9 1.1 5.4e-34 117.9 1.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.16 CCC69022.1 - 4.5e-34 118.0 0.4 4.5e-34 118.0 0.4 1.8 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 CCC69022.1 - 5.2e-08 33.5 1.0 2.2e-07 31.4 1.0 2.2 1 1 0 1 1 1 1 Ku70/Ku80 C-terminal arm FlhC PF05280.11 CCC69023.1 - 0.037 13.7 0.1 0.051 13.3 0.1 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) FeoB_associated PF12669.7 CCC69023.1 - 6.3 7.3 10.7 39 4.8 10.7 2.0 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein FlhC PF05280.11 CCC69024.1 - 0.037 13.7 0.1 0.051 13.3 0.1 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) FeoB_associated PF12669.7 CCC69024.1 - 6.3 7.3 10.7 39 4.8 10.7 2.0 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Rit1_C PF17184.4 CCC69025.1 - 2e-96 322.6 0.0 2.6e-96 322.2 0.0 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 CCC69025.1 - 4.9e-26 91.2 0.4 4.9e-26 91.2 0.4 1.9 2 0 0 2 2 2 1 Rit1 DUSP-like domain PRP38 PF03371.15 CCC69026.1 - 1.4e-47 161.8 4.6 1.7e-47 161.5 4.6 1.0 1 0 0 1 1 1 1 PRP38 family ATP13 PF12921.7 CCC69027.1 - 2.1e-22 79.1 0.6 9.6e-21 73.8 0.1 2.8 2 0 0 2 2 2 2 Mitochondrial ATPase expression PIG-L PF02585.17 CCC69028.1 - 1.2e-17 64.8 0.2 1.8e-17 64.2 0.2 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Fungal_trans PF04082.18 CCC69029.1 - 2.4e-36 125.2 6.1 8.4e-36 123.4 6.1 2.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC69029.1 - 2.8e-10 40.2 13.3 2.8e-10 40.2 13.3 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.15 CCC69029.1 - 3.5 7.8 5.4 0.96 9.6 1.4 2.2 2 0 0 2 2 2 0 Basic region leucine zipper MFS_1 PF07690.16 CCC69030.1 - 3.8e-33 114.9 56.5 7.1e-33 114.0 53.3 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC69030.1 - 1.5e-05 24.1 37.6 0.0028 16.6 13.4 3.4 1 1 0 2 2 2 2 Sugar (and other) transporter PGM_PMM_I PF02878.16 CCC69031.1 - 2.9e-37 127.5 0.0 4.9e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 CCC69031.1 - 3e-21 76.0 0.0 6.6e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 CCC69031.1 - 7e-14 52.0 0.0 1.3e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 CCC69031.1 - 2.3e-07 30.9 0.0 5.1e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain NIF PF03031.18 CCC69032.1 - 1.6e-26 92.9 0.6 1.1e-24 86.9 0.0 2.9 2 2 1 3 3 3 1 NLI interacting factor-like phosphatase BRCT PF00533.26 CCC69032.1 - 3.8e-13 49.6 0.6 9.5e-13 48.3 0.1 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 CCC69032.1 - 3.9e-05 23.5 0.0 9.5e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 CCC69032.1 - 0.0044 17.4 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain ATP-synt_J PF04911.12 CCC69032.1 - 0.02 14.5 0.2 0.036 13.6 0.2 1.4 1 0 0 1 1 1 0 ATP synthase j chain ubiquitin PF00240.23 CCC69033.1 - 1.5e-19 69.5 0.1 2.4e-19 68.8 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCC69033.1 - 2.7e-09 36.7 0.1 4.4e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 CCC69033.1 - 6.5e-06 25.9 1.4 6.8e-06 25.9 0.1 1.8 2 0 0 2 2 2 1 UBA/TS-N domain TBK1_ULD PF18396.1 CCC69033.1 - 0.0023 17.8 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 CCC69033.1 - 0.0033 17.8 0.1 0.0076 16.7 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain HOIP-UBA PF16678.5 CCC69033.1 - 0.0046 17.0 0.0 0.0084 16.1 0.0 1.3 1 0 0 1 1 1 1 HOIP UBA domain pair Rad60-SLD_2 PF13881.6 CCC69033.1 - 0.027 14.6 0.0 0.059 13.5 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 CCC69033.1 - 0.032 14.0 0.1 0.064 13.0 0.1 1.6 1 0 0 1 1 1 0 CUE domain TSP9 PF11493.8 CCC69033.1 - 0.15 12.7 2.2 0.67 10.7 0.1 2.5 2 0 0 2 2 2 0 Thylakoid soluble phosphoprotein TSP9 STI1 PF17830.1 CCC69033.1 - 0.43 10.5 17.9 5.1 7.1 6.5 3.4 1 1 1 2 2 2 0 STI1 domain GerD PF17898.1 CCC69033.1 - 0.44 10.5 5.6 1 9.3 5.5 1.7 1 1 0 1 1 1 0 Spore germination GerD central core domain Bul1_N PF04425.12 CCC69034.1 - 1.3e-162 541.7 0.0 1.3e-162 541.7 0.0 2.9 3 0 0 3 3 3 1 Bul1 N terminus Bul1_C PF04426.12 CCC69034.1 - 1.1e-104 349.6 18.0 1.1e-104 349.6 18.0 2.4 2 0 0 2 2 2 1 Bul1 C terminus GAT PF03127.14 CCC69034.1 - 0.2 12.0 3.0 0.23 11.8 1.2 2.0 2 0 0 2 2 2 0 GAT domain Bul1_N PF04425.12 CCC69035.1 - 1.1e-173 578.2 0.1 1.1e-173 578.2 0.1 2.5 2 1 1 3 3 3 1 Bul1 N terminus Bul1_C PF04426.12 CCC69035.1 - 1.3e-118 395.3 11.8 1.3e-118 395.3 11.8 2.2 2 0 0 2 2 2 1 Bul1 C terminus CPBP PF02517.16 CCC69036.1 - 4.9e-14 52.5 4.1 4.9e-14 52.5 4.1 1.9 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease Cyt-b5 PF00173.28 CCC69037.1 - 1.7e-17 63.3 0.3 5.4e-17 61.7 0.2 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 CCC69037.1 - 1.2e-13 51.6 14.9 1.2e-13 51.6 14.9 2.1 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 CCC69037.1 - 0.018 15.2 0.1 0.058 13.6 0.1 1.8 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Pribosyltran PF00156.27 CCC69038.1 - 5.9e-16 58.4 0.3 8e-16 58.0 0.3 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RRN9 PF10680.9 CCC69039.1 - 5.1e-16 58.7 0.2 1.6e-15 57.1 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor Cupredoxin_1 PF13473.6 CCC69039.1 - 0.048 13.8 1.2 1.4 9.0 1.2 2.7 1 1 0 1 1 1 0 Cupredoxin-like domain RNA_polI_A34 PF08208.11 CCC69040.1 - 0.001 19.2 33.3 0.0013 18.9 33.3 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 G-patch PF01585.23 CCC69040.1 - 0.0078 16.1 0.8 0.038 13.9 0.8 2.2 1 1 0 1 1 1 1 G-patch domain DDHD PF02862.17 CCC69040.1 - 0.047 13.8 5.5 0.059 13.5 5.5 1.4 1 0 0 1 1 1 0 DDHD domain PA26 PF04636.13 CCC69040.1 - 0.29 10.0 6.6 0.35 9.7 6.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SLC12 PF03522.15 CCC69040.1 - 4.3 6.3 15.7 5.4 5.9 15.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 RRM_1 PF00076.22 CCC69041.1 - 5.3e-39 131.9 2.2 3.5e-14 52.4 0.1 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCC69041.1 - 3.6e-34 116.5 0.1 2.6e-27 94.5 0.1 4.3 4 0 0 4 4 4 2 Occluded RNA-recognition motif Lsm_interact PF05391.11 CCC69041.1 - 1e-06 28.0 5.1 3.5e-06 26.3 5.1 2.0 1 0 0 1 1 1 1 Lsm interaction motif PHM7_cyt PF14703.6 CCC69041.1 - 1.3e-05 25.5 0.5 0.16 12.2 0.0 3.4 2 2 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter RRM_5 PF13893.6 CCC69041.1 - 0.0037 16.9 0.9 0.43 10.2 0.0 3.4 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CCC69041.1 - 0.0097 15.9 0.0 3.5 7.7 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 CCC69041.1 - 0.03 14.4 0.1 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 RRM_Rrp7 PF17799.1 CCC69041.1 - 0.042 13.6 4.8 0.11 12.3 0.2 3.2 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain Pyrophosphatase PF00719.19 CCC69042.1 - 1.2e-51 174.7 0.0 1.7e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase SNAP PF14938.6 CCC69043.1 - 4.9e-107 357.6 8.2 5.5e-107 357.4 8.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 CCC69043.1 - 1.8e-05 25.0 2.1 5.5 7.9 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCC69043.1 - 3.4e-05 24.0 3.3 0.22 11.8 0.0 3.6 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCC69043.1 - 0.00034 20.4 0.3 0.22 11.6 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 CCC69043.1 - 0.00062 19.7 1.1 3.2 8.1 0.1 4.7 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCC69043.1 - 0.0008 19.1 2.7 1.1 9.2 0.1 4.9 4 2 1 5 5 5 1 Tetratricopeptide repeat DHR-2 PF06920.13 CCC69043.1 - 0.001 17.8 0.7 0.0033 16.2 0.1 1.8 1 1 1 2 2 2 1 Dock homology region 2 TPR_19 PF14559.6 CCC69043.1 - 0.0019 18.7 1.9 1.6 9.3 0.2 4.3 3 2 1 4 4 4 1 Tetratricopeptide repeat Endonuc-MspI PF09208.10 CCC69043.1 - 0.002 17.6 0.2 0.0045 16.4 0.2 1.5 1 0 0 1 1 1 1 Restriction endonuclease MspI TPR_10 PF13374.6 CCC69043.1 - 0.017 15.0 0.2 17 5.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Spatacsin_C PF14649.6 CCC69043.1 - 0.021 14.0 1.0 0.13 11.3 0.2 2.3 1 1 1 2 2 2 0 Spatacsin C-terminus TPR_16 PF13432.6 CCC69043.1 - 0.028 15.1 0.0 0.12 13.0 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 CCC69043.1 - 0.083 12.5 0.1 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 Foie gras liver health family 1 TPR_11 PF13414.6 CCC69043.1 - 0.094 12.4 4.1 8.7 6.1 0.2 4.3 4 1 1 5 5 5 0 TPR repeat SchA_CurD PF04486.12 CCC69043.1 - 0.099 12.7 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 SchA/CurD like domain DUF2225 PF09986.9 CCC69043.1 - 0.28 10.9 5.0 1.7 8.3 1.7 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_8 PF13181.6 CCC69043.1 - 2.7 8.4 8.8 1.9 8.9 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RSN1_7TM PF02714.15 CCC69044.1 - 1.3e-92 310.0 25.4 1.3e-92 310.0 25.4 1.9 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CCC69044.1 - 2e-42 144.6 1.8 2e-42 144.6 1.8 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_ext PF12621.8 CCC69044.1 - 3.8e-27 94.3 0.0 1.2e-26 92.6 0.0 2.0 1 0 0 1 1 1 1 Extracellular tail, of 10TM putative phosphate transporter PHM7_cyt PF14703.6 CCC69044.1 - 1.1e-26 94.2 0.4 1.7e-26 93.5 0.4 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter HAD_SAK_1 PF10307.9 CCC69045.1 - 1.2e-55 188.5 0.4 1.9e-55 187.9 0.4 1.3 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Csm4_C PF17953.1 CCC69045.1 - 0.11 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 CRISPR Csm4 C-terminal domain Cue1_U7BR PF18499.1 CCC69046.1 - 1.9e-24 85.4 4.7 3.5e-24 84.6 4.7 1.5 1 0 0 1 1 1 1 Ubc7p-binding region of Cue1 CUE PF02845.16 CCC69046.1 - 4.4e-11 42.3 0.1 7.1e-11 41.6 0.1 1.4 1 0 0 1 1 1 1 CUE domain Inp1 PF12634.7 CCC69046.1 - 0.038 14.0 0.1 0.049 13.6 0.1 1.2 1 0 0 1 1 1 0 Inheritance of peroxisomes protein 1 SAP30_Sin3_bdg PF13867.6 CCC69047.1 - 4.8e-11 42.8 0.7 8.6e-08 32.4 0.2 2.7 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 TatD_DNase PF01026.21 CCC69048.1 - 1.4e-35 123.0 0.0 1.6e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase zf-UBP_var PF17807.1 CCC69048.1 - 0.018 14.8 0.1 0.04 13.7 0.1 1.6 1 0 0 1 1 1 0 Variant UBP zinc finger eIF-1a PF01176.19 CCC69049.1 - 9.2e-20 70.2 0.1 1.3e-19 69.8 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 TPR_8 PF13181.6 CCC69050.1 - 0.059 13.6 1.1 0.6 10.5 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat COX7a PF02238.15 CCC69051.1 - 9.5e-20 70.7 0.3 1.1e-19 70.6 0.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VII GFD1 PF17331.2 CCC69052.1 - 1e-05 25.5 16.7 3.1e-05 24.0 16.7 1.9 1 0 0 1 1 1 1 GFD1 mRNA transport factor EamA PF00892.20 CCC69053.1 - 1.1e-26 93.7 33.9 2.3e-15 57.0 9.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 CCC69053.1 - 2.1e-05 24.2 17.1 0.00068 19.2 17.1 2.0 1 1 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 CCC69053.1 - 0.00045 19.3 0.8 0.00045 19.3 0.8 2.1 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Frag1 PF10277.9 CCC69053.1 - 0.0012 18.5 4.3 0.0033 17.0 4.3 1.9 1 1 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF2070 PF09843.9 CCC69053.1 - 5.1 5.3 20.2 2.3 6.4 8.6 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) UPF0060 PF02694.15 CCC69053.1 - 6.1 7.1 13.2 9.2 6.6 0.9 2.8 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Cellulase-like PF12876.7 CCC69054.1 - 0.046 13.1 0.2 0.058 12.7 0.2 1.1 1 0 0 1 1 1 0 Sugar-binding cellulase-like Regulator_TrmB PF11495.8 CCC69054.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Pyridoxal_deC PF00282.19 CCC69056.1 - 1.1e-56 192.2 0.0 1.7e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Vitelline_membr PF10542.9 CCC69056.1 - 0.095 12.6 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Vitelline membrane cysteine-rich region SAM_decarbox PF01536.16 CCC69057.1 - 4.6e-136 453.5 10.2 5.3e-136 453.3 10.2 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase IFT81_CH PF18383.1 CCC69057.1 - 0.039 14.2 0.3 3.8 7.8 0.2 2.4 2 0 0 2 2 2 0 Intraflagellar transport 81 calponin homology domain zf-RING_2 PF13639.6 CCC69058.1 - 3.4e-07 30.5 7.4 8.9e-07 29.1 7.4 1.8 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.8 CCC69058.1 - 2.3e-05 24.5 5.2 8.8e-05 22.6 5.2 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 CCC69058.1 - 0.00013 22.2 6.8 0.00031 21.0 6.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCC69058.1 - 0.00074 19.5 1.8 0.0017 18.4 1.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 CCC69058.1 - 0.014 15.3 7.9 0.039 13.8 7.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCC69058.1 - 0.039 13.8 7.3 0.11 12.4 7.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.11 CCC69058.1 - 0.057 13.7 7.0 0.14 12.5 7.0 1.7 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 CCC69058.1 - 0.065 13.4 5.8 0.16 12.1 5.8 1.8 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 CCC69058.1 - 0.067 13.1 5.0 1.8 8.5 5.0 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 CCC69058.1 - 0.095 12.5 5.6 0.68 9.8 0.9 2.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 CCC69058.1 - 0.24 11.1 4.0 0.52 10.0 4.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CelTOS PF18659.1 CCC69058.1 - 0.35 11.3 5.5 0.13 12.7 0.2 3.2 3 0 0 3 3 1 0 Cell-traversal protein for ookinetes and sporozoites PWI PF01480.17 CCC69058.1 - 0.4 11.0 4.3 1.8 9.0 0.3 3.7 1 1 1 2 2 2 0 PWI domain zf-UDP PF14569.6 CCC69058.1 - 1.2 9.3 3.2 21 5.3 0.8 2.6 1 1 1 2 2 2 0 Zinc-binding RING-finger PHD PF00628.29 CCC69058.1 - 2.3 8.2 5.8 4.7 7.2 5.8 1.6 1 0 0 1 1 1 0 PHD-finger Prok-RING_4 PF14447.6 CCC69058.1 - 3.9 7.4 6.4 2.3 8.2 0.5 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Glyco_transf_8 PF01501.20 CCC69059.1 - 0.0037 16.9 7.6 0.0052 16.4 5.3 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 CCC69059.1 - 0.014 14.8 0.4 0.026 13.9 0.4 1.5 1 0 0 1 1 1 0 Mannosyltransferase putative AMP-binding PF00501.28 CCC69060.1 - 5.9e-85 285.4 0.0 8.5e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCC69060.1 - 0.0071 17.3 0.0 0.021 15.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain COX6B PF02297.17 CCC69061.1 - 6.1e-22 77.6 2.9 8.5e-22 77.2 2.9 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Bac_rhodopsin PF01036.18 CCC69062.1 - 2.5e-56 190.8 17.8 2.9e-56 190.6 17.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.6 CCC69062.1 - 0.68 9.6 11.1 0.63 9.7 0.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cation_efflux PF01545.21 CCC69064.1 - 1.7e-54 184.6 1.9 2.2e-54 184.2 1.9 1.1 1 0 0 1 1 1 1 Cation efflux family DUF2809 PF10990.8 CCC69064.1 - 0.27 11.9 1.7 15 6.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2809) DUF1082 PF06449.11 CCC69064.1 - 0.54 10.1 1.8 1.2 9.0 1.8 1.6 1 0 0 1 1 1 0 Mitochondrial domain of unknown function (DUF1082) Ribosomal_L18A PF01775.17 CCC69065.1 - 3e-43 146.8 3.7 3e-43 146.8 3.7 1.4 2 0 0 2 2 2 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Mito_carr PF00153.27 CCC69066.1 - 1.2e-31 108.5 5.2 2.4e-13 49.8 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF382 PF04037.13 CCC69068.1 - 9.3e-53 177.7 0.1 9.3e-53 177.7 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.16 CCC69068.1 - 7.5e-22 76.9 2.4 1.3e-21 76.2 2.4 1.4 1 0 0 1 1 1 1 PSP RNase_3_N PF18497.1 CCC69069.1 - 1e-39 135.0 1.6 2.7e-39 133.7 1.6 1.8 1 0 0 1 1 1 1 Ribonuclease III N-terminal domain Ribonuclease_3 PF00636.26 CCC69069.1 - 2.5e-14 53.8 0.0 2.5e-14 53.8 0.0 3.9 3 1 1 4 4 4 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.6 CCC69069.1 - 2.9e-11 43.6 0.0 9.7e-11 41.9 0.0 2.0 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.26 CCC69069.1 - 0.00012 22.7 0.0 0.00012 22.7 0.0 3.6 2 1 1 3 3 3 1 Double-stranded RNA binding motif RCC1 PF00415.18 CCC69070.1 - 4.4e-19 68.8 0.4 9.5e-08 32.5 0.0 5.1 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 CCC69070.1 - 4.5e-12 46.2 13.5 1.2e-08 35.1 0.1 4.6 3 2 1 4 4 4 3 BTB/POZ domain RCC1_2 PF13540.6 CCC69070.1 - 4.7e-10 39.0 7.8 0.0064 16.3 0.0 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat TFIID-31kDa PF02291.15 CCC69072.1 - 3e-47 159.7 0.0 3.5e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit MBF1 PF08523.10 CCC69073.1 - 1.8e-24 85.9 1.7 1.8e-24 85.9 1.7 2.1 2 1 1 3 3 3 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 CCC69073.1 - 1e-13 51.1 0.3 1.7e-13 50.4 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 CCC69073.1 - 5.1e-06 26.7 0.0 8.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 CCC69073.1 - 0.0061 16.6 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain LRR_6 PF13516.6 CCC69074.1 - 2.9e-13 48.7 12.3 0.19 11.9 0.1 7.8 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.7 CCC69074.1 - 2.6e-10 40.4 24.2 0.98 9.9 0.0 7.3 4 2 4 9 9 9 7 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 CCC69074.1 - 1.7e-07 30.8 9.5 37 5.4 0.0 7.8 7 0 0 7 7 7 0 Leucine Rich Repeat LRR_8 PF13855.6 CCC69074.1 - 8.6e-05 22.2 20.7 5.9 6.7 0.1 6.7 4 2 0 4 4 4 4 Leucine rich repeat Adaptin_binding PF10199.9 CCC69074.1 - 0.55 10.9 11.0 1.3 9.6 11.0 1.6 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF3801 PF12687.7 CCC69074.1 - 6 6.9 8.4 27 4.8 4.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3801) Cauli_VI PF01693.16 CCC69075.1 - 1.7e-30 105.0 9.1 2e-20 72.8 4.2 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.24 CCC69075.1 - 4.9e-29 101.3 0.0 7.9e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 RNase H SWIB PF02201.18 CCC69076.1 - 1.6e-27 95.2 1.1 3.4e-27 94.1 0.5 1.9 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.11 CCC69076.1 - 1.1e-13 50.8 0.1 7.5e-13 48.2 0.1 2.4 2 1 0 2 2 2 1 DEK C terminal domain NARP1 PF12569.8 CCC69076.1 - 2.1 7.1 11.0 2.8 6.7 11.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.16 CCC69076.1 - 2.7 8.0 4.7 3.5 7.6 4.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 CCC69076.1 - 7 5.3 5.8 8.1 5.1 5.8 1.1 1 0 0 1 1 1 0 Presenilin RhoGEF PF00621.20 CCC69077.1 - 1.7e-09 38.2 6.8 1.7e-09 38.2 6.8 3.1 2 1 1 3 3 3 2 RhoGEF domain VPS11_C PF12451.8 CCC69078.1 - 2e-09 37.5 2.2 2.5e-09 37.2 0.1 2.4 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 CCC69078.1 - 1.7e-06 27.9 4.3 4.9e-06 26.5 4.3 1.8 1 1 0 1 1 1 1 Zinc-finger zf-RING_UBOX PF13445.6 CCC69078.1 - 4.9e-06 26.5 2.2 1.7e-05 24.8 2.2 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CCC69078.1 - 0.00036 20.3 4.3 0.001 18.9 4.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCC69078.1 - 0.0004 20.3 4.7 0.0013 18.6 4.7 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 CCC69078.1 - 0.004 17.3 4.1 0.012 15.8 4.1 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING PHD PF00628.29 CCC69078.1 - 0.0095 15.8 3.2 0.022 14.6 3.2 1.7 1 0 0 1 1 1 1 PHD-finger Zn_ribbon_17 PF17120.5 CCC69078.1 - 0.021 14.4 1.7 0.041 13.5 1.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 CCC69078.1 - 0.023 14.6 3.8 0.058 13.3 3.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CCC69078.1 - 0.063 13.6 2.4 0.15 12.4 2.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCC69078.1 - 0.27 11.3 1.0 0.53 10.4 1.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CCC69078.1 - 0.3 11.0 2.6 0.59 10.0 2.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Mut7-C PF01927.16 CCC69078.1 - 0.38 10.8 3.4 0.71 10.0 0.8 2.5 2 0 0 2 2 2 0 Mut7-C RNAse domain zf-C3HC4_3 PF13920.6 CCC69078.1 - 0.57 10.1 3.0 1.1 9.1 3.0 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 CCC69078.1 - 0.69 9.9 3.4 0.43 10.5 0.5 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.6 CCC69078.1 - 1.1 9.7 10.8 0.037 14.4 4.3 2.0 2 0 0 2 2 2 0 Ring finger domain S10_plectin PF03501.15 CCC69079.1 - 1.5e-42 143.6 0.6 1.7e-42 143.4 0.6 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF4364 PF14277.6 CCC69079.1 - 0.017 14.9 0.2 0.023 14.4 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4364) HTH_45 PF14947.6 CCC69079.1 - 0.05 13.6 0.3 0.089 12.8 0.3 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix MsyB PF13984.6 CCC69079.1 - 0.061 13.6 0.0 0.08 13.3 0.0 1.3 1 0 0 1 1 1 0 MsyB protein PadR PF03551.14 CCC69079.1 - 0.064 13.2 0.4 0.064 13.2 0.4 1.8 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family S1 PF00575.23 CCC69080.1 - 1.1e-43 147.4 30.2 2.2e-12 47.1 0.3 12.8 12 1 1 13 13 13 6 S1 RNA binding domain Suf PF05843.14 CCC69080.1 - 6.7e-07 29.6 25.1 3.4e-05 24.0 3.8 4.6 2 1 3 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.6 CCC69080.1 - 1.1e-05 25.9 0.0 0.23 12.0 0.0 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCC69080.1 - 4e-05 24.1 0.1 4.5 8.4 0.0 4.7 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 CCC69080.1 - 0.00026 21.6 0.0 0.35 11.6 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CCC69080.1 - 0.014 14.6 0.4 0.16 11.1 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.12 CCC69080.1 - 0.072 13.1 0.0 0.44 10.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CsrA PF02599.16 CCC69080.1 - 0.12 12.3 0.0 0.12 12.3 0.0 2.9 3 0 0 3 3 3 0 Global regulator protein family Ribosomal_S4e PF00900.20 CCC69080.1 - 0.74 9.8 3.5 0.54 10.2 0.8 2.3 2 0 0 2 2 2 0 Ribosomal family S4e RrnaAD PF00398.20 CCC69081.1 - 4.9e-60 202.8 0.6 5.9e-60 202.6 0.6 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TAFII55_N PF04658.13 CCC69082.1 - 6e-51 172.3 0.1 6e-51 172.3 0.1 3.4 4 1 1 5 5 5 1 TAFII55 protein conserved region DUF5036 PF16439.5 CCC69082.1 - 0.08 12.6 1.3 0.17 11.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5036) SNF2_N PF00176.23 CCC69083.1 - 1.2e-71 241.3 0.9 2.8e-71 240.1 0.9 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCC69083.1 - 3.7e-20 72.3 0.7 1.1e-18 67.6 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.6 CCC69083.1 - 2.4e-16 60.1 2.7 2.4e-16 60.1 2.7 3.8 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex Bromodomain PF00439.25 CCC69083.1 - 5.1e-15 55.3 0.5 1.6e-14 53.7 0.5 1.9 1 0 0 1 1 1 1 Bromodomain QLQ PF08880.11 CCC69083.1 - 1.2e-10 40.9 1.4 3.9e-10 39.3 1.4 2.0 1 0 0 1 1 1 1 QLQ ResIII PF04851.15 CCC69083.1 - 7.3e-09 35.9 0.9 3.5e-08 33.6 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HSA PF07529.13 CCC69083.1 - 0.00071 19.9 5.9 0.00071 19.9 5.9 4.1 3 0 0 3 3 3 1 HSA MFS_1 PF07690.16 CCC69084.1 - 1.2e-11 44.2 29.3 1.6e-11 43.8 26.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily FSH1 PF03959.13 CCC69085.1 - 1.2e-60 204.8 0.0 1.3e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 CCC69085.1 - 0.0013 18.6 0.0 0.0099 15.7 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 CCC69085.1 - 0.053 12.8 0.0 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Esterase_phd PF10503.9 CCC69085.1 - 0.21 11.0 0.0 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Mre11_DNA_bind PF04152.14 CCC69086.1 - 5.7e-50 169.9 0.2 1.3e-49 168.7 0.2 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 CCC69086.1 - 3e-11 44.2 1.4 6.1e-11 43.2 1.4 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CCC69086.1 - 0.041 14.1 0.0 0.55 10.4 0.0 2.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Sorting_nexin PF03700.13 CCC69086.1 - 0.65 10.6 8.3 0.43 11.1 6.1 1.8 1 1 1 2 2 2 0 Sorting nexin, N-terminal domain MRP_L53 PF10780.9 CCC69087.1 - 3.7e-19 68.6 0.4 5.8e-19 68.0 0.1 1.5 2 0 0 2 2 2 1 39S ribosomal protein L53/MRP-L53 adh_short PF00106.25 CCC69088.1 - 6.3e-51 172.6 0.1 7.6e-51 172.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCC69088.1 - 1.3e-33 116.5 0.0 1.6e-33 116.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCC69088.1 - 3.5e-09 36.8 0.0 5e-09 36.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCC69088.1 - 0.085 12.0 0.1 0.16 11.1 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_S19 PF00203.21 CCC69088.1 - 0.1 12.5 0.2 3.7 7.5 0.1 2.4 1 1 1 2 2 2 0 Ribosomal protein S19 GHMP_kinases_N PF00288.26 CCC69090.1 - 2e-16 60.0 0.5 3.9e-15 55.8 0.5 2.5 2 1 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCC69090.1 - 1.6e-05 25.2 0.0 3.2e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal TRAPPC10 PF12584.8 CCC69092.1 - 2.5e-14 53.3 0.0 4.8e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Prefoldin_3 PF13758.6 CCC69092.1 - 0.018 15.1 0.0 0.058 13.5 0.0 1.9 1 0 0 1 1 1 0 Prefoldin subunit Pkinase PF00069.25 CCC69093.1 - 1.1e-42 146.3 0.5 9.7e-21 74.3 0.4 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69093.1 - 3.4e-11 42.9 1.2 1.6e-07 30.9 0.3 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_72 PF03198.14 CCC69094.1 - 2e-129 431.4 5.7 3.1e-129 430.8 5.7 1.3 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.17 CCC69094.1 - 8.4e-06 25.1 0.1 1.4e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.18 CCC69094.1 - 0.00067 19.2 0.1 0.0038 16.7 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HGTP_anticodon PF03129.20 CCC69094.1 - 0.085 13.0 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Anticodon binding domain DUF3446 PF11928.8 CCC69094.1 - 0.9 9.9 13.3 6.6 7.1 13.9 2.2 2 0 0 2 2 2 0 Early growth response N-terminal domain Myb_DNA-binding PF00249.31 CCC69095.1 - 1.3e-20 73.3 0.9 1.3e-09 38.1 0.3 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCC69095.1 - 4e-19 68.6 2.3 1.3e-12 47.7 1.0 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_Cef PF11831.8 CCC69095.1 - 0.00064 19.4 1.8 0.00064 19.4 1.8 2.9 2 1 1 3 3 3 1 pre-mRNA splicing factor component Rap1_C PF11626.8 CCC69095.1 - 0.0068 16.5 0.2 0.04 14.0 0.0 2.5 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain MCM_N PF14551.6 CCC69095.1 - 0.026 15.1 2.4 0.43 11.2 0.2 3.1 3 0 0 3 3 3 0 MCM N-terminal domain HTH_40 PF14493.6 CCC69095.1 - 0.04 14.4 1.1 0.33 11.4 0.4 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain RICH PF05062.12 CCC69095.1 - 0.31 11.4 9.7 0.12 12.8 5.7 2.4 2 0 0 2 2 2 0 RICH domain Tubulin_3 PF14881.6 CCC69097.1 - 2.3e-26 92.6 0.1 4.9e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CCC69097.1 - 4.5e-18 65.7 0.3 1.1e-17 64.4 0.1 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.25 CCC69097.1 - 0.00013 22.2 0.0 0.00067 19.9 0.0 2.1 2 1 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Abhydrolase_1 PF00561.20 CCC69098.1 - 1.4e-15 57.6 0.0 2.9e-15 56.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCC69098.1 - 1.1e-08 34.6 0.0 1.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF915 PF06028.11 CCC69098.1 - 0.00012 21.5 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.7 CCC69098.1 - 0.0076 16.9 0.0 0.011 16.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.22 CCC69098.1 - 0.0087 16.0 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.25 CCC69098.1 - 0.016 15.1 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) VirJ PF06057.11 CCC69098.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Ins_allergen_rp PF06757.13 CCC69098.1 - 0.036 14.0 0.0 12 5.9 0.0 2.3 2 0 0 2 2 2 0 Insect allergen related repeat, nitrile-specifier detoxification N2227 PF07942.12 CCC69099.1 - 1.3e-63 214.8 0.7 2.2e-63 214.0 0.7 1.4 1 0 0 1 1 1 1 N2227-like protein GHMP_kinases_N PF00288.26 CCC69100.1 - 1.1e-15 57.6 0.1 2.4e-15 56.5 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCC69100.1 - 4.1e-05 23.9 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Pkinase PF00069.25 CCC69101.1 - 1.7e-46 158.8 0.1 1.4e-45 155.8 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69101.1 - 7.8e-25 87.6 0.0 1.6e-24 86.6 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CCC69101.1 - 0.0045 16.6 0.0 0.55 9.8 0.0 2.7 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 MitMem_reg PF13012.6 CCC69102.1 - 1.5e-33 115.5 0.3 3e-33 114.6 0.3 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 CCC69102.1 - 1.2e-31 109.2 0.0 2.4e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UbiA PF01040.18 CCC69103.1 - 1.1e-48 165.7 15.2 1.5e-48 165.3 15.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family FA_desaturase PF00487.24 CCC69103.1 - 2.2 8.0 15.1 0.099 12.5 6.7 2.1 1 1 1 2 2 2 0 Fatty acid desaturase KOW PF00467.29 CCC69104.1 - 0.11 12.4 1.6 0.27 11.3 1.6 1.6 1 0 0 1 1 1 0 KOW motif EF-hand_7 PF13499.6 CCC69105.1 - 1.2e-24 86.5 13.6 9.2e-15 54.9 2.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CCC69105.1 - 1.6e-23 80.4 16.0 1.3e-07 30.7 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 CCC69105.1 - 2e-18 64.7 15.1 6.3e-07 28.8 0.2 4.5 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 CCC69105.1 - 3e-16 59.0 14.5 2e-09 37.2 0.8 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CCC69105.1 - 1.6e-09 38.0 0.8 0.0001 22.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 CCC69105.1 - 7e-08 31.6 14.4 2.1e-05 23.8 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 CCC69105.1 - 1.8e-05 24.6 4.2 0.0042 17.0 0.2 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.13 CCC69105.1 - 0.003 17.5 1.0 0.75 9.7 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 CCC69105.1 - 0.0076 16.6 5.1 1.1 9.6 0.6 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region MgtE_N PF03448.17 CCC69105.1 - 0.014 15.9 3.9 0.16 12.6 0.7 2.7 3 0 0 3 3 3 0 MgtE intracellular N domain DUF1296 PF06972.11 CCC69105.1 - 0.074 13.2 0.8 5 7.3 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1296) EF-hand_14 PF17959.1 CCC69105.1 - 0.09 13.1 1.8 5.6 7.4 0.1 2.3 1 1 1 2 2 2 0 EF-hand domain PhetRS_B1 PF18262.1 CCC69105.1 - 0.32 11.2 4.0 0.29 11.4 2.1 2.0 2 1 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain CAP_GLY PF01302.25 CCC69106.1 - 5.1e-18 64.9 1.3 9.8e-18 63.9 1.3 1.5 1 0 0 1 1 1 1 CAP-Gly domain KASH_CCD PF14662.6 CCC69106.1 - 0.084 12.7 72.7 0.049 13.5 15.7 5.2 2 2 3 5 5 5 0 Coiled-coil region of CCDC155 or KASH SRP1_TIP1 PF00660.17 CCC69106.1 - 1.5 8.9 5.0 2.4 8.3 0.3 3.2 3 0 0 3 3 3 0 Seripauperin and TIP1 family PIGA PF08288.12 CCC69107.1 - 4.8e-43 145.7 2.2 4.8e-43 145.7 2.2 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 CCC69107.1 - 8.6e-32 110.5 2.3 1.7e-31 109.5 2.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 CCC69107.1 - 7.7e-26 90.6 0.0 1.4e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCC69107.1 - 1.5e-21 77.3 0.0 3.7e-21 75.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 CCC69107.1 - 1.1e-16 61.7 0.0 1.9e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 CCC69107.1 - 8.5e-05 22.6 0.1 0.00031 20.8 0.3 1.8 2 0 0 2 2 2 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 CCC69107.1 - 0.01 16.2 0.0 0.026 14.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 CCC69107.1 - 0.17 11.6 1.2 0.85 9.3 0.1 2.3 1 1 1 2 2 2 0 Starch synthase catalytic domain TFR_dimer PF04253.15 CCC69108.1 - 3.9e-31 107.7 0.0 7.8e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CCC69108.1 - 0.008 15.9 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M28 Cyt-b5 PF00173.28 CCC69109.1 - 4.4e-13 49.2 0.0 6.6e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PH_BEACH PF14844.6 CCC69110.1 - 0.085 13.0 0.2 0.085 13.0 0.2 1.9 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH RRM_9 PF18444.1 CCC69111.1 - 1.3e-33 114.6 0.2 2.7e-33 113.6 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif TAP_C PF03943.13 CCC69111.1 - 1.9e-13 49.8 0.2 4.5e-13 48.6 0.2 1.7 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.6 CCC69111.1 - 6.2e-08 32.3 3.2 1.2e-07 31.4 3.2 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 CCC69111.1 - 0.00015 22.1 11.1 0.003 17.9 1.9 3.7 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) DnaJ PF00226.31 CCC69112.1 - 8.7e-17 61.0 0.5 3.2e-16 59.2 0.5 2.1 1 0 0 1 1 1 1 DnaJ domain Sporozoite_P67 PF05642.11 CCC69112.1 - 0.035 12.2 1.0 0.068 11.3 1.0 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sec63 PF02889.16 CCC69112.1 - 0.045 12.9 0.0 0.16 11.1 0.0 1.9 2 1 0 2 2 2 0 Sec63 Brl domain Astro_capsid_p PF12226.8 CCC69112.1 - 0.52 9.4 12.1 0.74 8.9 12.1 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Acetyltransf_10 PF13673.7 CCC69113.1 - 2.6e-09 37.1 0.0 4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCC69113.1 - 2e-08 34.6 0.0 2.9e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCC69113.1 - 3.7e-08 33.6 0.0 5.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 CCC69113.1 - 0.0013 18.9 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCC69113.1 - 0.061 13.3 0.0 0.098 12.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Peptidase_C54 PF03416.19 CCC69113.1 - 0.11 11.9 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 Peptidase family C54 FolB PF02152.18 CCC69114.1 - 0.017 15.7 0.5 0.09 13.3 0.1 2.3 3 0 0 3 3 3 0 Dihydroneopterin aldolase DUF4177 PF13783.6 CCC69114.1 - 0.07 13.4 0.1 0.28 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4177) DNA_pol_B PF00136.21 CCC69115.1 - 3.2e-108 362.4 2.2 3.2e-108 362.4 2.2 2.2 3 0 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 CCC69115.1 - 5e-22 78.5 3.5 6e-12 45.4 1.5 2.6 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 CCC69115.1 - 6.1e-10 39.4 6.6 1.7e-09 38.0 6.6 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DCR PF14047.6 CCC69115.1 - 0.067 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Dppa2/4 conserved region HypA PF01155.19 CCC69115.1 - 0.11 12.5 3.8 2.9 8.0 0.4 2.6 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Atg29_N PF18388.1 CCC69116.1 - 1.3e-16 60.1 0.6 1.3e-16 60.1 0.6 1.9 2 0 0 2 2 2 1 Atg29 N-terminal domain Myb_DNA-bind_6 PF13921.6 CCC69116.1 - 0.031 14.5 2.5 0.08 13.2 2.5 1.7 1 0 0 1 1 1 0 Myb-like DNA-binding domain SET PF00856.28 CCC69117.1 - 2.1e-11 44.5 0.3 9.1e-11 42.4 0.3 1.9 1 1 0 1 1 1 1 SET domain YHS PF04945.13 CCC69117.1 - 0.029 14.5 0.1 0.029 14.5 0.1 2.1 2 0 0 2 2 2 0 YHS domain HATPase_c_3 PF13589.6 CCC69118.1 - 6.2e-11 42.3 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.11 CCC69118.1 - 3.3e-09 36.7 0.0 3.1e-08 33.5 0.1 2.2 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.26 CCC69118.1 - 0.0003 21.3 0.0 0.00066 20.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Xrn1_D3 PF18194.1 CCC69118.1 - 0.0097 16.0 0.6 0.43 10.7 0.1 3.3 3 0 0 3 3 3 1 Exoribonuclease 1 Domain-3 NAPRTase PF04095.16 CCC69118.1 - 0.012 15.2 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family STIMATE PF12400.8 CCC69120.1 - 1.6e-45 154.7 5.1 1.6e-45 154.7 5.1 2.0 2 1 0 2 2 2 1 STIMATE family DUF2208 PF09973.9 CCC69120.1 - 0.07 12.7 2.6 0.15 11.7 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Pet20 PF08692.10 CCC69121.1 - 3e-16 60.3 4.6 1.3e-13 51.8 0.2 3.2 2 1 0 2 2 2 1 Mitochondrial protein Pet20 Tox-REase-3 PF15647.6 CCC69121.1 - 3 8.2 6.6 0.59 10.4 1.2 2.4 2 1 1 3 3 3 0 Restriction endonuclease fold toxin 3 Methyltransf_15 PF09445.10 CCC69123.1 - 8.8e-66 220.5 0.1 1.4e-65 219.9 0.1 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.18 CCC69123.1 - 2.8e-06 27.2 0.1 3.7e-05 23.5 0.1 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 CCC69123.1 - 7.4e-06 26.6 0.0 1.4e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC69123.1 - 1.4e-05 24.9 0.0 2.5e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 CCC69123.1 - 0.0019 18.0 2.7 0.0096 15.6 0.0 2.7 1 1 1 2 2 2 1 DNA methylase MethyltransfD12 PF02086.15 CCC69123.1 - 0.0055 16.4 0.5 0.013 15.2 0.0 1.8 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase tRNA_U5-meth_tr PF05958.11 CCC69123.1 - 0.023 13.7 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Cons_hypoth95 PF03602.15 CCC69123.1 - 0.034 13.8 0.0 0.08 12.6 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 MTS PF05175.14 CCC69123.1 - 0.039 13.5 0.0 0.095 12.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_11 PF08241.12 CCC69123.1 - 0.046 14.4 0.0 0.099 13.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CCC69123.1 - 0.048 13.5 0.0 0.053 13.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain BCA_ABC_TP_C PF12399.8 CCC69124.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Kinesin PF00225.23 CCC69125.1 - 4.6e-105 351.2 0.1 6.9e-105 350.7 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CCC69125.1 - 1.7e-20 73.5 0.0 6.3e-20 71.6 0.0 2.0 2 0 0 2 2 2 1 Microtubule binding PKcGMP_CC PF16808.5 CCC69125.1 - 0.006 16.4 10.3 0.24 11.3 0.5 3.4 3 0 0 3 3 3 2 Coiled-coil N-terminus of cGMP-dependent protein kinase XLF PF09302.11 CCC69125.1 - 0.015 15.5 5.0 1.2 9.3 1.2 2.8 2 1 0 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF536 PF04394.14 CCC69125.1 - 0.024 14.5 2.7 0.024 14.5 2.7 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF536 UPF0227 PF05728.12 CCC69125.1 - 0.15 12.0 0.2 12 5.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) MPS2 PF17060.5 CCC69125.1 - 0.15 11.3 5.0 0.41 9.9 2.3 2.2 2 0 0 2 2 2 0 Monopolar spindle protein 2 FlxA PF14282.6 CCC69125.1 - 0.5 10.4 6.8 3.7 7.6 0.2 3.1 2 0 0 2 2 2 0 FlxA-like protein Fib_alpha PF08702.10 CCC69125.1 - 1.3 9.2 5.1 18 5.5 0.5 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.14 CCC69125.1 - 2.8 7.7 8.1 8.9 6.1 1.5 2.7 2 1 0 2 2 2 0 Hepatic lectin, N-terminal domain Med9 PF07544.13 CCC69125.1 - 7.9 6.6 12.7 8.2 6.6 2.8 3.4 3 1 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 Asp PF00026.23 CCC69126.1 - 3.6e-106 355.1 0.0 4.6e-106 354.8 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCC69126.1 - 8e-16 58.8 0.3 2e-13 51.0 0.3 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 CCC69126.1 - 0.0023 18.5 0.0 0.14 12.8 0.0 2.8 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 CCC69126.1 - 0.0031 18.1 0.0 0.2 12.2 0.0 2.6 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 CCC69126.1 - 0.0034 17.2 0.0 0.017 14.9 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Pkinase PF00069.25 CCC69127.1 - 2.5e-80 269.6 0.0 4.6e-80 268.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69127.1 - 1.1e-38 133.1 0.0 2.2e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CCC69127.1 - 1.4e-24 86.2 1.6 4e-12 46.3 0.2 2.9 2 0 0 2 2 2 2 FHA domain Kinase-like PF14531.6 CCC69127.1 - 2.9e-09 36.7 0.0 6.9e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Yop-YscD_cpl PF16697.5 CCC69127.1 - 6.3e-07 29.6 0.1 0.0017 18.6 0.0 2.8 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 CCC69127.1 - 3.7e-05 23.8 0.0 0.0073 16.2 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CCC69127.1 - 3.7e-05 23.2 0.0 7.8e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FHA_2 PF17913.1 CCC69127.1 - 0.00014 22.0 0.5 1.3 9.3 0.0 3.6 3 0 0 3 3 3 1 FHA domain RIO1 PF01163.22 CCC69127.1 - 0.0073 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Mei5 PF10376.9 CCC69128.1 - 7.2e-20 71.7 29.3 1.7e-19 70.6 29.0 1.6 1 1 0 1 1 1 1 Double-strand recombination repair protein Tfb2 PF03849.14 CCC69129.1 - 1.7e-141 471.3 2.0 2.3e-141 470.9 2.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 CCC69129.1 - 1.6e-21 76.5 0.2 4.3e-21 75.1 0.2 1.8 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 CCC69129.1 - 9.4e-06 25.8 0.0 2.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Ribonuclease_T2 PF00445.18 CCC69130.1 - 3.2e-39 135.1 0.6 3.2e-39 135.1 0.6 1.5 2 0 0 2 2 2 1 Ribonuclease T2 family CENP-F_leu_zip PF10473.9 CCC69131.1 - 0.0069 16.4 5.0 0.0069 16.4 5.0 1.8 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KASH_CCD PF14662.6 CCC69131.1 - 0.0098 15.7 6.3 0.016 15.0 6.3 1.2 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Pox_A3L PF05288.11 CCC69131.1 - 0.063 13.3 2.1 0.14 12.2 2.1 1.5 1 0 0 1 1 1 0 Poxvirus A3L Protein Spc29 PF17082.5 CCC69131.1 - 0.083 12.7 15.8 8.6 6.1 15.8 2.8 1 1 0 1 1 1 0 Spindle Pole Component 29 MalF_P2 PF14785.6 CCC69131.1 - 0.083 12.9 0.4 0.14 12.2 0.4 1.3 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain Fib_alpha PF08702.10 CCC69131.1 - 0.088 13.0 2.3 0.26 11.5 0.1 2.5 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family DUF2968 PF11180.8 CCC69131.1 - 0.1 12.2 1.6 0.16 11.6 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TSNAXIP1_N PF15739.5 CCC69131.1 - 0.97 9.8 6.8 3.4 8.1 5.4 2.1 2 0 0 2 2 2 0 Translin-associated factor X-interacting N-terminus BRE1 PF08647.11 CCC69131.1 - 5.8 7.1 11.5 2.4 8.3 8.7 1.8 2 0 0 2 2 2 0 BRE1 E3 ubiquitin ligase Y_phosphatase PF00102.27 CCC69132.1 - 2.2e-58 197.6 3.4 9.5e-53 179.2 1.2 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 CCC69132.1 - 0.004 17.0 0.0 0.032 14.0 0.0 2.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CCC69132.1 - 0.0042 17.1 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family DUF2689 PF10894.8 CCC69132.1 - 0.024 14.4 0.1 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2689) PTPlike_phytase PF14566.6 CCC69132.1 - 0.087 12.9 0.0 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 Inositol hexakisphosphate IBN_N PF03810.19 CCC69133.1 - 5.6e-15 55.0 0.2 2.7e-14 52.8 0.2 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CCC69133.1 - 0.0033 17.5 12.4 0.02 14.9 0.1 5.4 4 2 0 4 4 4 2 Exportin 1-like protein Mog1 PF04603.12 CCC69133.1 - 0.0093 16.3 0.1 0.027 14.8 0.1 1.7 1 0 0 1 1 1 1 Ran-interacting Mog1 protein NAPRTase PF04095.16 CCC69134.1 - 1.1e-73 247.8 0.2 1.4e-73 247.5 0.2 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_N PF17767.1 CCC69134.1 - 1e-34 119.6 0.1 1.8e-34 118.8 0.1 1.4 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain WD40 PF00400.32 CCC69135.1 - 2.6e-05 24.9 5.5 0.0088 16.9 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC69135.1 - 0.00044 20.5 2.3 52 4.2 0.0 6.0 5 1 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Linker_histone PF00538.19 CCC69136.1 - 5.2e-46 154.9 8.6 1.4e-24 86.2 0.1 3.0 3 0 0 3 3 3 2 linker histone H1 and H5 family MSC PF09402.10 CCC69136.1 - 0.035 13.6 1.8 0.14 11.6 0.4 2.0 1 1 1 2 2 2 0 Man1-Src1p-C-terminal domain TRF PF08558.10 CCC69137.1 - 3.5e-75 252.7 0.0 5.4e-75 252.1 0.0 1.3 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.31 CCC69137.1 - 9.5e-09 35.3 0.6 2.6e-08 33.9 0.4 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCC69137.1 - 0.0063 16.8 0.2 0.019 15.2 0.1 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF573 PF04504.14 CCC69137.1 - 0.15 12.8 5.8 0.14 12.8 2.3 2.8 2 1 0 2 2 2 0 Protein of unknown function, DUF573 YEATS PF03366.16 CCC69138.1 - 4.2e-21 74.7 0.1 6.4e-21 74.1 0.1 1.3 1 0 0 1 1 1 1 YEATS family BET PF17035.5 CCC69138.1 - 8e-06 25.9 0.1 1.9e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Mucin PF01456.17 CCC69139.1 - 0.0061 16.6 8.8 0.0061 16.6 8.8 1.5 2 0 0 2 2 2 1 Mucin-like glycoprotein FSA_C PF10479.9 CCC69139.1 - 0.015 13.4 3.7 0.021 13.0 3.7 1.3 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Roughex PF06020.11 CCC69139.1 - 3.8 6.5 11.1 5 6.1 11.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Sporozoite_P67 PF05642.11 CCC69139.1 - 8.3 4.4 15.0 30 2.5 15.0 1.7 1 1 0 1 1 1 0 Sporozoite P67 surface antigen DPPIV_N PF00930.21 CCC69140.1 - 2.8e-86 289.5 0.7 4.2e-86 288.9 0.7 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 CCC69140.1 - 1.1e-49 168.8 0.5 1.7e-49 168.1 0.5 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CCC69140.1 - 0.00099 18.8 0.0 0.21 11.2 0.0 2.4 1 1 1 2 2 2 2 alpha/beta hydrolase fold PAF-AH_p_II PF03403.13 CCC69140.1 - 0.0015 17.1 0.0 0.0032 16.1 0.0 1.5 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II OAD_gamma PF04277.13 CCC69140.1 - 0.004 17.7 0.1 0.0078 16.8 0.1 1.4 1 0 0 1 1 1 1 Oxaloacetate decarboxylase, gamma chain Hydrolase_4 PF12146.8 CCC69140.1 - 0.008 15.5 0.0 3.6 6.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Esterase PF00756.20 CCC69140.1 - 0.015 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 CCC69140.1 - 0.019 14.8 0.0 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.7 CCC69140.1 - 0.025 15.2 0.0 0.87 10.1 0.0 2.2 1 1 1 2 2 2 0 Alpha/beta hydrolase family Ribosomal_L5e PF17144.4 CCC69141.1 - 3.1e-83 277.6 0.0 5.5e-83 276.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 CCC69141.1 - 3.1e-31 108.1 1.7 3.1e-31 108.1 1.7 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Ribosomal_L18p PF00861.22 CCC69141.1 - 0.0045 17.4 0.4 0.017 15.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Thr_synth_N PF14821.6 CCC69141.1 - 0.018 15.2 0.4 1.4 9.1 0.0 2.8 3 0 0 3 3 3 0 Threonine synthase N terminus Com_YlbF PF06133.11 CCC69141.1 - 0.03 14.9 1.7 0.068 13.8 1.7 1.6 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA NAC PF01849.18 CCC69141.1 - 0.044 13.8 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 NAC domain Phage_holin_3_3 PF16083.5 CCC69141.1 - 0.13 12.4 0.0 1.9 8.7 0.0 2.3 2 0 0 2 2 2 0 LydA holin phage, holin superfamily III CtaG_Cox11 PF04442.14 CCC69142.1 - 8.9e-61 204.3 0.0 1.5e-60 203.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Zn_clus PF00172.18 CCC69143.1 - 2.4e-06 27.6 9.5 5.3e-06 26.5 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SUIM_assoc PF16619.5 CCC69143.1 - 0.031 14.4 4.7 0.099 12.7 4.7 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 CCC69143.1 - 0.13 12.2 4.0 0.17 11.8 4.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NifU_N PF01592.16 CCC69144.1 - 1.6e-55 186.7 0.1 2e-55 186.4 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain TSCPD PF12637.7 CCC69144.1 - 0.026 14.8 0.2 0.047 13.9 0.2 1.4 1 0 0 1 1 1 0 TSCPD domain AAA_27 PF13514.6 CCC69145.1 - 0.093 12.3 1.0 0.25 10.9 1.0 1.7 1 0 0 1 1 1 0 AAA domain LRR_4 PF12799.7 CCC69145.1 - 0.49 10.9 16.9 0.031 14.7 4.2 4.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) PHD PF00628.29 CCC69146.1 - 1.8e-11 43.8 5.1 4.3e-11 42.5 5.1 1.7 1 0 0 1 1 1 1 PHD-finger Bunya_NS-S PF01104.17 CCC69146.1 - 0.061 13.1 0.3 0.11 12.3 0.3 1.3 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s zf-RING_2 PF13639.6 CCC69146.1 - 1.3 9.4 7.0 5.1 7.5 7.0 2.0 1 0 0 1 1 1 0 Ring finger domain WD40 PF00400.32 CCC69147.1 - 0.0032 18.3 4.2 2.5 9.1 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF4241 PF14025.6 CCC69147.1 - 0.036 14.3 0.1 0.28 11.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4241) Pkinase PF00069.25 CCC69148.1 - 9e-71 238.3 0.0 1.3e-70 237.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69148.1 - 1.2e-36 126.4 0.0 2.5e-36 125.3 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC69148.1 - 7.4e-09 35.3 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCC69148.1 - 8.2e-05 21.6 0.0 0.00016 20.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 CCC69148.1 - 0.00065 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CCC69148.1 - 0.002 17.8 0.0 0.31 10.7 0.0 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCC69148.1 - 0.015 15.2 0.0 0.09 12.7 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 CCC69149.1 - 1.3e-62 211.6 0.1 2.8e-62 210.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69149.1 - 3.2e-37 128.2 0.0 5e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC69149.1 - 3.7e-09 36.3 0.0 6.6e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCC69149.1 - 0.0088 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 CCC69149.1 - 0.15 11.6 0.1 0.15 11.6 0.1 1.8 2 0 0 2 2 2 0 RIO1 family Ribosomal_L35Ae PF01247.18 CCC69150.1 - 1e-41 141.0 0.7 1.1e-41 140.8 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.18 CCC69150.1 - 0.0073 16.5 0.0 3.8 7.8 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Oxysterol_BP PF01237.18 CCC69151.1 - 3.3e-61 207.2 1.2 2.9e-53 181.0 0.0 2.1 1 1 1 2 2 2 2 Oxysterol-binding protein Nop53 PF07767.11 CCC69152.1 - 1.6e-99 334.0 53.5 2.1e-99 333.6 53.5 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF3439 PF11921.8 CCC69152.1 - 0.0049 16.8 4.6 0.01 15.8 4.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) ACPS PF01648.20 CCC69153.1 - 1.2e-13 51.1 0.0 2.3e-13 50.3 0.0 1.5 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily APG5 PF04106.12 CCC69155.1 - 5.8e-38 130.7 0.3 1e-37 130.0 0.3 1.4 1 1 0 1 1 1 1 Autophagy protein Apg5 SGT1 PF07093.11 CCC69156.1 - 4.8e-12 45.1 0.0 4.8e-12 45.1 0.0 2.1 2 0 0 2 2 2 1 SGT1 protein Plasmid_parti PF01672.16 CCC69156.1 - 0.12 13.0 1.9 0.21 12.2 0.2 2.4 2 1 0 2 2 2 0 Putative plasmid partition protein WD40 PF00400.32 CCC69158.1 - 1.7e-31 107.7 18.0 4.2e-06 27.4 0.4 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC69158.1 - 2.9e-05 24.3 1.6 0.22 11.9 0.1 4.1 2 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CCC69158.1 - 0.003 16.4 3.0 8.4 5.0 0.0 4.7 2 1 3 5 5 5 3 Nup133 N terminal like WD40_like PF17005.5 CCC69158.1 - 0.062 12.6 0.0 3.5 6.9 0.0 2.5 2 0 0 2 2 2 0 WD40-like domain PTPA PF03095.15 CCC69159.1 - 1.2e-115 386.1 0.3 1.4e-115 385.9 0.3 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein EXS PF03124.14 CCC69160.1 - 2.5e-86 290.0 25.4 3.5e-86 289.5 25.4 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 CCC69160.1 - 6.9e-35 121.7 18.4 1.5e-21 77.8 3.4 2.6 2 1 1 3 3 3 2 SPX domain APG6 PF04111.12 CCC69161.1 - 9.8e-61 204.8 0.2 2.7e-60 203.4 0.2 1.8 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 CCC69161.1 - 2.2e-29 102.7 21.7 2.2e-29 102.7 21.7 2.5 4 0 0 4 4 4 1 Apg6 coiled-coil region AGH PF17558.2 CCC69161.1 - 0.073 13.2 0.8 4.6 7.4 0.0 2.7 3 0 0 3 3 3 0 Androgenic gland hormone DUF4600 PF15372.6 CCC69161.1 - 0.97 9.9 21.0 0.056 13.9 14.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) FAM76 PF16046.5 CCC69161.1 - 2.7 7.3 10.5 5 6.4 10.5 1.5 1 0 0 1 1 1 0 FAM76 protein Ax_dynein_light PF10211.9 CCC69161.1 - 4.4 7.2 25.0 0.43 10.5 18.0 2.8 2 2 1 3 3 3 0 Axonemal dynein light chain PRP1_N PF06424.12 CCC69161.1 - 9.8 6.6 16.0 2.1 8.8 12.3 1.7 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DEAD PF00270.29 CCC69162.1 - 1.4e-48 165.0 0.0 7.9e-48 162.5 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC69162.1 - 4.1e-33 114.1 0.0 1.2e-32 112.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC69162.1 - 0.0017 18.4 0.0 0.0057 16.7 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCC69162.1 - 0.0089 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF844 PF05815.11 CCC69162.1 - 0.057 12.6 0.0 0.08 12.1 0.0 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Gly_rich PF12810.7 CCC69162.1 - 0.76 9.6 57.6 0.31 10.9 21.1 2.4 2 0 0 2 2 2 0 Glycine rich protein Mit_ribos_Mrp51 PF11709.8 CCC69163.1 - 2.6e-64 218.1 8.5 3.9e-63 214.2 8.5 2.5 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit NUDIX PF00293.28 CCC69164.1 - 6.4e-26 90.9 0.0 1.1e-25 90.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Peptidase_C14 PF00656.22 CCC69165.1 - 3.7e-59 200.7 0.1 5.1e-59 200.2 0.1 1.1 1 0 0 1 1 1 1 Caspase domain MltA PF03562.17 CCC69165.1 - 0.42 10.3 2.4 0.91 9.3 2.4 1.5 1 0 0 1 1 1 0 MltA specific insert domain Hist_deacetyl PF00850.19 CCC69166.1 - 7.4e-52 176.7 0.1 1.3e-51 175.9 0.1 1.4 1 0 0 1 1 1 1 Histone deacetylase domain RhoGAP PF00620.27 CCC69167.1 - 4.4e-35 120.7 0.1 1.3e-34 119.3 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 CCC69167.1 - 8.7e-10 39.1 0.4 5e-09 36.6 0.1 2.4 2 0 0 2 2 2 1 PH domain PX PF00787.24 CCC69167.1 - 0.00013 21.9 2.3 0.00028 20.8 0.7 2.3 2 0 0 2 2 2 1 PX domain Csm1_N PF18504.1 CCC69167.1 - 0.34 11.3 3.4 0.21 11.9 0.2 2.4 3 0 0 3 3 3 0 Csm1 N-terminal domain PY_rept_46 PF09689.10 CCC69167.1 - 4.3 8.0 9.8 2.7 8.7 6.2 2.6 2 0 0 2 2 2 0 Plasmodium yoelii repeat (PY_rept_46) TFIIA PF03153.13 CCC69168.1 - 3.3e-48 165.7 19.9 5e-27 96.0 8.6 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit 2-Hacid_dh_C PF02826.19 CCC69169.1 - 2.7e-37 127.8 0.0 4.3e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 CCC69169.1 - 3.1e-05 24.2 0.0 5.8e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 CCC69169.1 - 0.0092 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 CCC69169.1 - 0.07 13.2 0.0 0.18 11.9 0.0 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PEX11 PF05648.14 CCC69170.1 - 3.1e-07 30.1 4.5 3.1e-07 30.1 4.5 1.8 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4508 PF14969.6 CCC69170.1 - 0.027 14.7 0.1 0.027 14.7 0.1 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4508) HD_2 PF12917.7 CCC69170.1 - 0.045 13.5 3.5 0.93 9.2 0.1 3.1 3 0 0 3 3 3 0 HD containing hydrolase-like enzyme M PF02370.16 CCC69170.1 - 0.079 13.5 2.1 0.4 11.4 2.1 2.3 1 0 0 1 1 1 0 M protein repeat Arginase PF00491.21 CCC69171.1 - 1.5e-74 251.1 0.0 1.7e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family EnY2 PF10163.9 CCC69171.1 - 0.19 12.1 0.0 0.41 11.1 0.0 1.6 1 0 0 1 1 1 0 Transcription factor e(y)2 GDPD PF03009.17 CCC69172.1 - 2.1e-77 260.3 0.0 4.5e-77 259.3 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 CCC69172.1 - 2e-19 69.9 1.1 1.5e-15 57.5 0.0 4.0 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCC69172.1 - 1.6e-16 60.2 1.4 2.6e-09 37.1 0.2 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCC69172.1 - 1.2e-14 54.4 0.1 1.4e-07 32.0 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CCC69172.1 - 2.4e-13 49.8 0.2 3.8e-05 23.9 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CCC69172.1 - 5.7e-13 47.8 1.2 6.1e-05 23.1 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat NanE PF04131.14 CCC69172.1 - 0.0076 15.5 0.4 0.14 11.3 0.0 2.7 4 0 0 4 4 4 1 Putative N-acetylmannosamine-6-phosphate epimerase SecA_SW PF07516.13 CCC69172.1 - 0.0086 16.2 1.4 0.024 14.7 1.4 1.8 1 0 0 1 1 1 1 SecA Wing and Scaffold domain ABC1 PF03109.16 CCC69173.1 - 1.4e-21 76.8 0.0 3e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 CCC69173.1 - 0.075 12.6 0.6 0.19 11.3 0.1 1.8 2 0 0 2 2 2 0 RIO1 family Arf PF00025.21 CCC69174.1 - 7.3e-76 253.5 0.1 8.3e-76 253.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCC69174.1 - 2.4e-15 56.8 0.0 3.1e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CCC69174.1 - 8.9e-11 41.5 0.0 1.1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 CCC69174.1 - 1.3e-10 41.1 0.0 1.5e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 CCC69174.1 - 1.2e-09 37.8 0.2 1.2e-05 24.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCC69174.1 - 2.7e-09 36.7 0.0 3.4e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCC69174.1 - 0.00024 21.2 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCC69174.1 - 0.00037 20.1 0.1 0.0032 17.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 CCC69174.1 - 0.00089 19.8 0.4 0.0035 17.9 0.4 1.8 1 1 0 1 1 1 1 ABC transporter MeaB PF03308.16 CCC69174.1 - 0.0074 15.3 0.3 0.2 10.6 0.1 2.5 2 1 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CCC69174.1 - 0.051 14.1 0.1 0.095 13.2 0.1 1.5 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 CCC69174.1 - 0.12 11.9 0.7 9 5.8 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Oxidored-like PF09791.9 CCC69176.1 - 1.2e-24 85.7 2.1 2.1e-24 84.9 2.1 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal HSP70 PF00012.20 CCC69177.1 - 4.1e-176 586.7 1.1 5e-176 586.4 1.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCC69177.1 - 5.7e-12 45.1 0.2 2.7e-11 42.9 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 CCC69177.1 - 0.00018 21.9 0.4 0.0029 18.0 0.1 2.6 2 1 0 2 2 2 1 Cell division protein FtsA PilM_2 PF11104.8 CCC69177.1 - 0.0019 17.3 0.1 0.06 12.4 0.0 2.3 2 0 0 2 2 2 1 Type IV pilus assembly protein PilM; NLE PF08154.12 CCC69177.1 - 0.077 13.5 0.0 0.27 11.8 0.0 2.0 1 0 0 1 1 1 0 NLE (NUC135) domain Raco_middle PF17651.1 CCC69177.1 - 0.079 12.6 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 RACo middle region DUF1627 PF07789.12 CCC69177.1 - 0.32 10.6 3.7 0.46 10.1 0.2 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1627) GYF PF02213.16 CCC69178.1 - 1.9e-15 56.2 0.3 4e-15 55.2 0.3 1.6 1 0 0 1 1 1 1 GYF domain GYF_2 PF14237.6 CCC69178.1 - 0.015 15.1 0.2 0.054 13.3 0.2 2.0 1 0 0 1 1 1 0 GYF domain 2 BSP_II PF05432.11 CCC69178.1 - 9.8 5.8 29.3 16 5.0 29.3 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) tRNA-synt_2 PF00152.20 CCC69179.1 - 1.4e-97 326.5 0.4 2e-97 326.1 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCC69179.1 - 1.2e-08 34.8 0.3 2.7e-08 33.7 0.3 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCC69179.1 - 0.00062 19.3 0.5 0.0057 16.2 0.0 2.5 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) S4_2 PF13275.6 CCC69179.1 - 0.013 15.3 0.2 0.25 11.2 0.1 2.5 2 0 0 2 2 2 0 S4 domain MafB PF06255.13 CCC69179.1 - 0.15 11.5 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Neisseria toxin MafB Lactamase_B_2 PF12706.7 CCC69180.1 - 5.9e-28 97.7 0.0 8.9e-28 97.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CCC69180.1 - 7.8e-11 42.1 0.0 1.4e-10 41.3 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain COX7a PF02238.15 CCC69180.1 - 0.24 11.8 1.9 0.53 10.7 1.9 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VII WD40 PF00400.32 CCC69181.1 - 0.0021 18.8 0.0 0.026 15.4 0.0 2.6 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF2192 PF09958.9 CCC69181.1 - 0.096 12.2 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) Rad4 PF03835.15 CCC69183.1 - 4.4e-10 39.4 3.3 1e-09 38.3 3.3 1.6 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 CCC69183.1 - 8.4e-10 39.1 0.5 2.6e-09 37.5 0.2 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily ZZ PF00569.17 CCC69183.1 - 0.021 14.7 0.5 9.5 6.1 0.1 2.6 2 0 0 2 2 2 0 Zinc finger, ZZ type PAW PF04721.17 CCC69183.1 - 0.055 13.3 1.6 0.087 12.6 1.6 1.3 1 0 0 1 1 1 0 PNGase C-terminal domain, mannose-binding module PAW Sec62 PF03839.16 CCC69184.1 - 1.9e-75 253.1 0.2 2.3e-75 252.8 0.2 1.0 1 0 0 1 1 1 1 Translocation protein Sec62 Baculo_11_kDa PF06143.11 CCC69184.1 - 7.1 6.3 6.6 27 4.4 3.4 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family SLAC1 PF03595.17 CCC69185.1 - 3.1e-80 269.9 36.5 3.6e-80 269.7 36.5 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel RNF111_N PF15303.6 CCC69185.1 - 0.11 12.2 0.3 0.16 11.7 0.3 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Pyr_redox_2 PF07992.14 CCC69186.1 - 5.4e-63 212.9 1.3 9e-63 212.2 1.3 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CCC69186.1 - 5.5e-34 116.7 6.5 8.3e-34 116.2 0.4 3.4 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CCC69186.1 - 2.1e-19 69.9 2.1 2.1e-19 69.9 2.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCC69186.1 - 1.4e-13 50.8 8.2 1.4e-12 47.5 8.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCC69186.1 - 3.6e-07 29.9 0.3 2.1e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.6 CCC69186.1 - 5.7e-05 22.4 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 CCC69186.1 - 0.00013 20.8 8.0 0.45 9.2 0.5 3.9 2 1 2 4 4 4 3 HI0933-like protein AlaDh_PNT_C PF01262.21 CCC69186.1 - 0.00014 21.2 2.9 0.081 12.2 0.2 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 CCC69186.1 - 0.00034 19.8 3.4 0.0052 15.9 0.9 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.18 CCC69186.1 - 0.021 14.7 0.3 0.021 14.7 0.3 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.19 CCC69186.1 - 0.03 13.7 1.4 1.5 8.1 0.0 3.0 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 CCC69186.1 - 0.091 12.0 1.7 6 6.0 0.2 2.5 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 CCC69186.1 - 3.7 7.0 6.1 5.5 6.5 0.1 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Ribosomal_S6e PF01092.19 CCC69187.1 - 9.4e-55 183.9 0.3 9.4e-55 183.9 0.3 1.7 2 0 0 2 2 2 1 Ribosomal protein S6e SRF-TF PF00319.18 CCC69188.1 - 7.4e-22 76.6 0.1 1.3e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) FAM176 PF14851.6 CCC69188.1 - 0.14 11.9 2.1 0.4 10.3 2.1 1.7 1 0 0 1 1 1 0 FAM176 family Med24_N PF11277.8 CCC69188.1 - 0.65 8.0 3.6 0.94 7.4 3.6 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal Aldo_ket_red PF00248.21 CCC69189.1 - 4.7e-59 200.0 0.0 5.3e-59 199.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.12 CCC69189.1 - 0.0045 16.6 0.1 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Ceramidase PF05875.12 CCC69190.1 - 2e-93 312.6 17.2 2.4e-93 312.4 17.2 1.0 1 0 0 1 1 1 1 Ceramidase DUF1129 PF06570.11 CCC69190.1 - 0.9 9.0 11.4 0.089 12.3 1.2 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF1129) Sec16_C PF12931.7 CCC69191.1 - 2.5e-79 267.1 0.1 4.4e-79 266.3 0.1 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 CCC69191.1 - 1.7e-10 41.5 0.0 1.1e-09 38.9 0.0 2.5 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region Nup96 PF12110.8 CCC69191.1 - 0.046 12.8 0.0 0.046 12.8 0.0 1.9 2 0 0 2 2 2 0 Nuclear protein 96 AAA PF00004.29 CCC69192.1 - 2.1e-32 112.3 0.0 4.5e-32 111.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCC69192.1 - 7e-08 32.8 0.2 8.8e-07 29.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCC69192.1 - 1.1e-06 29.1 0.1 3.6e-05 24.2 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 CCC69192.1 - 4.4e-05 23.5 1.4 0.0015 18.5 1.4 2.4 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 CCC69192.1 - 0.0003 21.1 0.8 0.017 15.5 0.0 3.1 4 0 0 4 4 2 1 RNA helicase AAA_11 PF13086.6 CCC69192.1 - 0.00031 20.6 0.0 0.00088 19.1 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCC69192.1 - 0.00071 20.1 0.0 0.0018 18.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CCC69192.1 - 0.0012 18.6 0.0 0.0051 16.6 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_5 PF07728.14 CCC69192.1 - 0.0022 18.0 0.1 0.011 15.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 CCC69192.1 - 0.0033 17.2 0.0 0.0079 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCC69192.1 - 0.0039 17.5 0.0 0.019 15.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CCC69192.1 - 0.0042 16.6 0.1 0.011 15.2 0.1 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 CCC69192.1 - 0.0054 16.0 0.0 0.012 14.9 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 CCC69192.1 - 0.018 15.2 0.1 0.087 12.9 0.1 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 CCC69192.1 - 0.018 15.0 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 CCC69192.1 - 0.021 14.8 0.1 0.051 13.5 0.1 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 CCC69192.1 - 0.028 14.1 0.0 0.067 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CCC69192.1 - 0.053 13.6 0.2 0.27 11.3 0.2 2.3 1 1 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CCC69192.1 - 0.061 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Cytidylate kinase AAA_17 PF13207.6 CCC69192.1 - 0.063 13.7 0.0 0.33 11.4 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA_2 PF07724.14 CCC69192.1 - 0.069 13.3 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Rad51 PF08423.11 CCC69192.1 - 0.069 12.4 0.3 3.5 6.8 0.3 2.2 1 1 0 1 1 1 0 Rad51 AAA_33 PF13671.6 CCC69192.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CCC69192.1 - 0.089 12.7 0.6 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 RsgA GTPase RuvB_N PF05496.12 CCC69192.1 - 0.093 12.5 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 CCC69192.1 - 0.096 13.2 0.1 0.38 11.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 CCC69192.1 - 0.17 11.4 0.0 0.38 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 CCC69192.1 - 0.32 11.5 6.3 0.053 14.0 0.6 2.5 1 1 1 2 2 2 0 AAA domain DUF3535 PF12054.8 CCC69193.1 - 9.2e-117 390.9 0.1 9.2e-117 390.9 0.1 3.2 5 0 0 5 5 5 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 CCC69193.1 - 2.4e-68 230.4 0.0 5.2e-68 229.3 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCC69193.1 - 1.6e-18 67.1 0.0 7.3e-18 64.9 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 CCC69193.1 - 1.7e-11 43.3 3.4 0.11 12.8 0.0 8.2 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.7 CCC69193.1 - 8.2e-06 26.3 0.1 0.44 11.2 0.1 4.8 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region ResIII PF04851.15 CCC69193.1 - 0.00011 22.2 0.0 0.00011 22.2 0.0 2.8 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit TAF6_C PF07571.13 CCC69193.1 - 0.0024 18.2 0.1 16 5.9 0.0 4.8 2 1 2 4 4 4 1 TAF6 C-terminal HEAT repeat domain UME PF08064.13 CCC69193.1 - 0.011 15.6 0.2 10 6.1 0.0 5.1 4 1 0 4 4 4 0 UME (NUC010) domain ERCC3_RAD25_C PF16203.5 CCC69193.1 - 0.017 14.4 0.0 0.041 13.1 0.0 1.6 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase GUN4_N PF16416.5 CCC69193.1 - 0.041 13.9 0.6 1.5 8.9 0.0 2.9 2 0 0 2 2 2 0 ARM-like repeat domain, GUN4-N terminal S4 PF01479.25 CCC69194.1 - 3.3e-13 49.1 0.2 1.2e-12 47.3 0.2 2.0 1 0 0 1 1 1 1 S4 domain Ribosomal_L21e PF01157.18 CCC69195.1 - 2.7e-48 162.0 4.6 2.7e-48 162.0 4.6 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.9 CCC69195.1 - 0.0027 17.3 0.0 0.0032 17.1 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Mt_ATP-synt_B PF05405.14 CCC69196.1 - 5.5e-54 182.2 9.2 6.6e-54 181.9 9.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) Rep_trans PF02486.19 CCC69196.1 - 0.04 13.7 1.1 0.063 13.0 0.7 1.5 1 1 0 1 1 1 0 Replication initiation factor YqgC PF17430.2 CCC69196.1 - 0.11 12.5 2.0 0.28 11.3 2.0 1.7 1 0 0 1 1 1 0 Uncharacterized YqgC-like DUF5315 PF17242.2 CCC69197.1 - 2e-23 82.0 2.5 2.2e-23 81.9 1.0 1.8 2 0 0 2 2 2 1 Disordered region of unknown function (DUF5315) GPI2 PF06432.11 CCC69198.1 - 1.1e-57 195.7 22.0 1.2e-57 195.5 22.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1204 PF06721.11 CCC69198.1 - 0.19 11.2 0.0 0.25 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) GCR1_C PF12550.8 CCC69199.1 - 1.6e-23 82.8 1.5 5.6e-23 81.1 1.5 2.0 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes TetR_C_17 PF17922.1 CCC69199.1 - 0.054 13.6 0.0 0.22 11.6 0.0 2.1 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AAA PF00004.29 CCC69200.1 - 6.4e-39 133.4 0.0 2.6e-38 131.4 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC69200.1 - 4.2e-10 39.3 0.1 3e-09 36.5 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 CCC69200.1 - 1e-07 31.8 0.1 2.9e-05 24.0 0.0 3.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 CCC69200.1 - 6.1e-06 26.1 0.0 1.2e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 CCC69200.1 - 0.00016 21.8 0.0 0.00016 21.8 0.0 3.5 5 1 0 5 5 3 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 CCC69200.1 - 0.00018 20.8 0.0 0.00018 20.8 0.0 2.0 2 0 0 2 2 1 1 TIP49 P-loop domain AAA_22 PF13401.6 CCC69200.1 - 0.00054 20.2 2.8 0.028 14.7 0.2 3.2 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CCC69200.1 - 0.0039 16.9 0.0 0.015 15.1 0.0 2.0 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CCC69200.1 - 0.0057 17.2 0.1 0.0057 17.2 0.1 4.1 3 2 1 4 4 3 1 AAA domain AAA_5 PF07728.14 CCC69200.1 - 0.007 16.4 0.0 0.032 14.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCC69200.1 - 0.023 14.1 0.0 0.053 12.9 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CCC69200.1 - 0.023 14.7 2.6 0.026 14.5 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.6 CCC69200.1 - 0.033 13.8 0.0 0.78 9.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CCC69200.1 - 0.033 14.6 6.1 0.037 14.4 0.1 3.2 2 2 1 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.22 CCC69200.1 - 0.053 13.9 0.1 0.42 11.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 CCC69200.1 - 0.064 12.8 0.0 0.14 11.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CCC69200.1 - 0.17 12.1 0.0 0.17 12.1 0.0 2.7 2 2 0 2 2 1 0 AAA domain UCH PF00443.29 CCC69201.1 - 3.5e-35 121.8 0.5 1.1e-34 120.0 0.5 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase VPS9 PF02204.18 CCC69203.1 - 1.5e-15 57.2 1.4 3.8e-15 56.0 1.4 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain polyprenyl_synt PF00348.17 CCC69204.1 - 3.3e-56 190.2 0.0 4e-56 189.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF3446 PF11928.8 CCC69207.1 - 0.18 12.2 12.8 0.32 11.3 6.4 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain Biopterin_H PF00351.21 CCC69208.1 - 0.0048 16.0 1.2 0.0074 15.4 1.2 1.3 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase VPS28 PF03997.12 CCC69209.1 - 2.2e-73 246.0 4.7 2.5e-73 245.8 4.7 1.0 1 0 0 1 1 1 1 VPS28 protein DnaG_DnaB_bind PF08278.11 CCC69209.1 - 0.039 14.6 0.1 0.16 12.5 0.0 1.9 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding DUF469 PF04320.14 CCC69209.1 - 0.098 13.5 0.2 0.32 11.9 0.0 1.9 2 1 0 2 2 2 0 Protein with unknown function (DUF469) DUF3417 PF11897.8 CCC69209.1 - 0.1 13.0 0.6 0.22 12.0 0.1 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3417) Pro_isomerase PF00160.21 CCC69210.1 - 8e-08 32.7 2.0 4.6e-07 30.2 0.0 2.6 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pes-10 PF07149.11 CCC69210.1 - 0.012 14.7 9.9 0.016 14.3 9.9 1.1 1 0 0 1 1 1 0 Pes-10 RSRP PF17069.5 CCC69210.1 - 0.26 10.8 1.0 0.36 10.4 1.0 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 CDC45 PF02724.14 CCC69210.1 - 0.35 9.1 6.1 0.45 8.7 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein NIF PF03031.18 CCC69211.1 - 6.5e-43 146.2 0.1 1e-42 145.6 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Aldedh PF00171.22 CCC69212.1 - 5e-176 585.8 0.0 5.6e-176 585.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CorA PF01544.18 CCC69213.1 - 0.00011 21.6 7.4 0.00022 20.7 7.4 1.6 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein TrbL PF04610.14 CCC69213.1 - 0.029 14.1 0.5 0.052 13.3 0.5 1.4 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Glutaredoxin PF00462.24 CCC69214.1 - 4.9e-18 65.1 0.0 9.5e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin ABC2_membrane PF01061.24 CCC69215.1 - 1.1e-61 207.9 50.1 5e-34 117.6 12.6 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CCC69215.1 - 5.8e-36 124.0 0.0 2.4e-17 63.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCC69215.1 - 3e-34 116.8 5.1 6.2e-30 103.0 0.1 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CCC69215.1 - 8.3e-08 32.7 0.0 1.9e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 CCC69215.1 - 1.9e-07 31.1 0.1 8.8e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CCC69215.1 - 9.2e-06 26.1 0.0 0.0047 17.3 0.0 2.9 2 1 1 3 3 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 CCC69215.1 - 0.00023 21.2 0.1 0.63 10.1 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 CCC69215.1 - 0.0003 20.0 9.9 0.0003 20.0 9.9 3.4 3 1 0 3 3 3 1 ABC-2 family transporter protein AAA_22 PF13401.6 CCC69215.1 - 0.00037 20.8 0.1 0.072 13.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 CCC69215.1 - 0.00053 19.5 0.0 2.8 7.3 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.12 CCC69215.1 - 0.00066 19.0 0.0 0.97 8.7 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_29 PF13555.6 CCC69215.1 - 0.00078 19.1 0.3 0.098 12.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 CCC69215.1 - 0.0016 18.1 0.2 0.05 13.2 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CCC69215.1 - 0.0024 18.4 0.0 0.089 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCC69215.1 - 0.0024 17.8 0.0 0.086 12.7 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.6 CCC69215.1 - 0.0029 17.5 0.0 2.8 7.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 CCC69215.1 - 0.0078 15.9 1.1 0.92 9.2 0.2 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCC69215.1 - 0.01 16.2 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.15 CCC69215.1 - 0.011 15.7 0.0 14 5.5 0.0 3.2 3 0 0 3 3 3 0 NTPase AAA_25 PF13481.6 CCC69215.1 - 0.014 15.0 0.1 0.2 11.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CCC69215.1 - 0.038 14.0 0.2 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ploopntkinase3 PF18751.1 CCC69215.1 - 0.041 13.8 0.1 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 CCC69215.1 - 0.058 13.6 0.1 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CCC69215.1 - 0.08 12.7 0.3 2.2 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CCC69215.1 - 0.11 12.9 0.0 3.7 8.0 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CCC69215.1 - 0.12 12.8 0.1 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CCC69215.1 - 0.19 10.9 0.5 6.1 5.9 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 CCC69215.1 - 0.3 11.6 0.9 0.51 10.8 0.1 1.7 2 0 0 2 2 1 0 AAA domain Oxidored_FMN PF00724.20 CCC69216.1 - 3.2e-134 447.5 0.0 3.9e-134 447.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Gly_transf_sug PF04488.15 CCC69217.1 - 1.8e-21 76.6 0.1 1e-20 74.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DinB PF05163.12 CCC69217.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 DinB family Lge1 PF11488.8 CCC69218.1 - 1.3e-17 63.7 0.6 1.8e-17 63.3 0.6 1.2 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 CAP_N PF01213.19 CCC69218.1 - 0.0066 16.0 0.8 0.008 15.7 0.8 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal zf_CCCH_4 PF18345.1 CCC69219.1 - 5.6e-11 42.1 19.4 1.1e-05 25.3 5.1 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH PF00642.24 CCC69219.1 - 2.2e-10 40.2 11.2 5.1e-06 26.2 2.8 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 CCC69219.1 - 2.3e-09 36.9 11.9 0.00011 21.9 3.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 CCC69219.1 - 8.2e-06 26.5 7.5 0.00056 20.6 1.0 3.5 3 1 1 4 4 4 2 Torus domain zf-CCCH_3 PF15663.5 CCC69219.1 - 0.0052 17.0 6.2 0.02 15.1 5.7 2.2 1 1 1 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 CCC69219.1 - 0.008 16.6 18.8 0.38 11.3 5.8 2.6 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Glyco_transf_15 PF01793.16 CCC69220.1 - 5e-101 338.2 11.8 6.6e-101 337.8 11.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase VanY PF02557.17 CCC69220.1 - 0.032 14.0 0.1 0.092 12.5 0.1 1.8 1 1 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase PTRF_SDPR PF15237.6 CCC69220.1 - 0.2 11.3 0.1 0.34 10.5 0.1 1.3 1 0 0 1 1 1 0 PTRF/SDPR family ODC_AZ PF02100.17 CCC69221.1 - 2.5e-06 27.4 0.0 3.7e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme RVT_thumb PF06817.14 CCC69221.1 - 0.071 13.0 0.9 0.31 10.9 0.5 2.1 2 0 0 2 2 2 0 Reverse transcriptase thumb domain Arf PF00025.21 CCC69222.1 - 1.4e-48 164.7 0.2 1.7e-48 164.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CCC69222.1 - 3.6e-17 62.4 0.0 4.3e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC69222.1 - 2.9e-14 53.3 0.0 4e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 CCC69222.1 - 9.5e-13 48.0 0.0 1.2e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCC69222.1 - 2.5e-11 43.3 0.4 8.9e-08 31.7 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit GTP_EFTU PF00009.27 CCC69222.1 - 6.6e-09 35.6 0.1 5.7e-08 32.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CCC69222.1 - 3.1e-07 30.4 0.0 4.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CCC69222.1 - 4.9e-07 29.4 0.1 6.1e-07 29.0 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 CCC69222.1 - 0.012 15.8 0.0 0.083 13.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain Anp1 PF03452.14 CCC69223.1 - 5.3e-108 360.4 0.1 6.4e-108 360.1 0.1 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.26 CCC69223.1 - 0.059 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 EF1G PF00647.19 CCC69224.1 - 1.9e-47 159.7 0.1 3.4e-47 158.9 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 CCC69224.1 - 2.5e-13 50.1 0.0 8.8e-13 48.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CCC69224.1 - 7.3e-11 42.1 0.0 7.3e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCC69224.1 - 9.9e-07 28.7 0.1 2.2e-06 27.6 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCC69224.1 - 5.5e-06 26.5 0.0 1.9e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCC69224.1 - 0.00013 22.3 0.0 0.00029 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Sgf11_N PF18519.1 CCC69225.1 - 2.1e-21 75.1 0.5 3e-21 74.7 0.5 1.2 1 0 0 1 1 1 1 SAGA-associated factor 11 N-terminal domain Sgf11 PF08209.11 CCC69225.1 - 4.2e-16 58.2 4.9 6.2e-16 57.7 4.9 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-CpG_bind_C PF12269.8 CCC69225.1 - 4.8e-05 23.2 0.0 4.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain VRP1 PF03538.14 CCC69225.1 - 0.035 13.5 0.1 0.04 13.3 0.1 1.1 1 0 0 1 1 1 0 Salmonella virulence plasmid 28.1kDa A protein zf_C2H2_13 PF18508.1 CCC69225.1 - 0.068 12.8 0.6 0.14 11.8 0.1 1.8 2 0 0 2 2 2 0 Zinc finger domain Skp1_POZ PF03931.15 CCC69226.1 - 1.4e-09 38.0 0.1 2.1e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Vps16_C PF04840.12 CCC69227.1 - 3.5e-83 279.3 7.4 5.2e-83 278.7 7.4 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 CCC69227.1 - 5.2e-78 262.6 0.1 6.9e-78 262.2 0.1 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region RRM_1 PF00076.22 CCC69228.1 - 5.4e-54 179.9 0.8 4e-17 61.8 0.1 5.7 5 1 1 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC69228.1 - 3.7e-09 36.6 0.1 0.011 15.8 0.0 4.3 4 0 0 4 4 4 2 RNA recognition motif RRM_Rrp7 PF17799.1 CCC69228.1 - 0.012 15.4 0.0 2.9 7.7 0.0 3.0 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain OSTbeta PF15048.6 CCC69228.1 - 0.072 13.2 0.3 0.072 13.2 0.3 3.8 4 0 0 4 4 4 0 Organic solute transporter subunit beta protein SID-1_RNA_chan PF13965.6 CCC69228.1 - 3.9 5.8 6.3 0.41 9.0 0.4 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Pkinase PF00069.25 CCC69229.1 - 1.7e-56 191.5 0.0 4.5e-55 186.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69229.1 - 9.2e-26 90.7 0.1 1.1e-24 87.1 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase FLILHELTA PF10306.9 CCC69230.1 - 6.9e-21 74.5 0.0 1.2e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA MT0933_antitox PF14013.6 CCC69230.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 MT0933-like antitoxin protein tRNA-synt_1 PF00133.22 CCC69231.1 - 3.4e-164 547.4 0.1 6e-164 546.6 0.0 1.3 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 CCC69231.1 - 3.4e-21 75.4 5.7 3.1e-12 45.9 0.1 4.0 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CCC69231.1 - 9.8e-18 64.6 0.3 2.2e-17 63.4 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 CCC69231.1 - 0.045 13.1 0.0 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.6 CCC69231.1 - 0.096 12.2 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 DZR PF12773.7 CCC69231.1 - 0.82 9.7 3.1 1.4 9.0 3.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_4 PF13894.6 CCC69233.1 - 1.3e-07 31.8 10.0 0.00047 20.8 0.3 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCC69233.1 - 3.5e-06 27.2 11.2 0.00094 19.5 0.5 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CCC69233.1 - 0.0015 18.7 0.7 0.082 13.2 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCC69233.1 - 0.0037 17.2 3.0 0.055 13.5 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 CCC69233.1 - 0.012 16.3 1.6 0.073 13.8 0.4 2.1 2 0 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats zf-H2C2_2 PF13465.6 CCC69233.1 - 0.035 14.5 4.0 1.2 9.7 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_11 PF16622.5 CCC69233.1 - 0.3 10.9 5.4 0.64 9.8 1.2 2.5 2 0 0 2 2 2 0 zinc-finger C2H2-type zf_UBZ PF18439.1 CCC69233.1 - 0.94 9.1 4.4 14 5.4 0.1 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger zf-C2HE PF16278.5 CCC69233.1 - 2.7 8.5 5.8 15 6.1 5.8 2.2 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger NAC PF01849.18 CCC69234.1 - 1.4e-15 57.0 1.0 1.9e-15 56.6 0.2 1.7 2 0 0 2 2 2 1 NAC domain Glyco_hydro_20b PF02838.15 CCC69234.1 - 0.11 13.3 0.6 0.29 11.9 0.6 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, domain 2 Aldo_ket_red PF00248.21 CCC69235.1 - 2.8e-56 190.9 0.1 3.3e-56 190.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.12 CCC69235.1 - 0.0014 18.3 0.1 0.0054 16.3 0.0 1.8 2 0 0 2 2 2 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) HpuA PF16960.5 CCC69235.1 - 0.081 12.1 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Haemoglobin-haptoglobin utilisation, porphyrin transporter RPN1_RPN2_N PF17781.1 CCC69235.1 - 0.092 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 RPN1/RPN2 N-terminal domain Phage_TAC_12 PF12363.8 CCC69235.1 - 0.24 11.8 2.1 13 6.2 0.3 2.9 2 1 1 3 3 3 0 Phage tail assembly chaperone protein, TAC ApbA_C PF08546.11 CCC69236.1 - 7.8e-05 22.9 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pkinase PF00069.25 CCC69237.1 - 1.4e-76 257.4 0.0 1.6e-76 257.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69237.1 - 1.9e-37 128.9 0.0 2.6e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCC69237.1 - 0.0037 16.3 0.0 0.014 14.3 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CCC69237.1 - 0.0099 15.2 0.0 0.023 14.0 0.0 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CCC69237.1 - 0.045 13.7 0.0 0.61 10.0 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CCC69237.1 - 0.078 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 AdoMet_MTase PF07757.13 CCC69238.1 - 1.6e-41 141.2 0.1 2.6e-41 140.5 0.1 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 CCC69238.1 - 0.0048 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 CCC69238.1 - 0.036 14.0 0.2 2.3 8.2 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain SUV3_C PF12513.8 CCC69239.1 - 1.6e-15 56.7 1.2 3.6e-15 55.6 1.2 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.31 CCC69239.1 - 8.2e-13 48.7 0.2 5.6e-12 46.0 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCC69239.1 - 0.0013 18.5 0.2 0.0076 16.0 0.0 2.3 4 0 0 4 4 4 1 DEAD/DEAH box helicase TK PF00265.18 CCC69239.1 - 0.084 12.7 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Thymidine kinase Thiolase_N PF00108.23 CCC69240.1 - 1.3e-95 319.7 2.9 1.6e-95 319.4 2.9 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 CCC69240.1 - 1.3e-45 154.0 3.3 3.7e-45 152.5 0.2 2.8 3 1 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 CCC69240.1 - 4.5e-06 26.4 1.0 1.1e-05 25.2 1.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 CCC69240.1 - 0.043 13.7 0.5 2.1 8.2 0.5 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pkinase PF00069.25 CCC69241.1 - 2.1e-49 168.3 0.3 1.9e-42 145.5 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69241.1 - 7.7e-23 81.1 0.1 2.5e-19 69.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCC69241.1 - 1.7e-06 27.6 0.0 3.4e-06 26.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 CCC69241.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family RMI1_N PF08585.12 CCC69242.1 - 2.5e-14 53.6 0.0 4e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 RecQ mediated genome instability protein DUF3684 PF12449.8 CCC69242.1 - 0.02 12.7 0.1 0.024 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) Spo7_2_N PF15407.6 CCC69242.1 - 0.089 12.4 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Sporulation protein family 7 MTHFR PF02219.17 CCC69243.1 - 1.5e-110 369.0 0.0 2e-110 368.7 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ERCC4 PF02732.15 CCC69244.1 - 9.6e-21 74.6 0.0 2.8e-20 73.1 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain DUF5595 PF18077.1 CCC69244.1 - 0.073 13.2 7.4 0.47 10.6 7.4 2.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) GIT_CC PF16559.5 CCC69244.1 - 0.23 11.3 5.3 1.7 8.6 2.9 3.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor ARID PF01388.21 CCC69245.1 - 9.6e-19 67.9 0.2 9.6e-19 67.9 0.2 4.4 4 1 0 4 4 4 1 ARID/BRIGHT DNA binding domain Torus PF16131.5 CCC69246.1 - 3.6e-34 117.7 0.7 2.2e-33 115.2 0.0 2.2 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 CCC69246.1 - 3.3e-07 30.0 0.0 6.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 CCC69246.1 - 0.53 10.2 7.9 1.1 9.2 7.9 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CCC69246.1 - 0.93 9.6 7.5 2.1 8.5 7.5 1.6 1 0 0 1 1 1 0 Zinc finger domain GLE1 PF07817.13 CCC69247.1 - 2.9e-89 298.6 0.3 2.9e-89 298.6 0.3 2.1 2 0 0 2 2 2 1 GLE1-like protein DUF2201_N PF13203.6 CCC69247.1 - 0.61 9.6 11.3 0.97 9.0 11.3 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Asp-B-Hydro_N PF05279.11 CCC69247.1 - 8.2 6.4 22.3 15 5.6 22.3 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Na_Ca_ex PF01699.24 CCC69248.1 - 7.3e-57 191.6 37.3 2.7e-32 111.8 6.2 3.2 3 1 0 3 3 3 2 Sodium/calcium exchanger protein Porphobil_deam PF01379.20 CCC69249.1 - 1.6e-71 240.0 0.0 2.1e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 CCC69249.1 - 6e-22 77.8 0.7 1e-21 77.1 0.7 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain CEP1-DNA_bind PF09287.10 CCC69249.1 - 0.011 15.4 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 CEP-1, DNA binding DUF4944 PF16302.5 CCC69249.1 - 0.18 11.9 0.1 0.59 10.2 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4944) Reticulon PF02453.17 CCC69250.1 - 2.1e-16 60.3 0.2 3.5e-16 59.6 0.2 1.4 1 0 0 1 1 1 1 Reticulon Sel1 PF08238.12 CCC69251.1 - 7.1e-26 90.1 15.1 1.6e-05 25.4 0.1 8.3 8 1 0 8 8 8 6 Sel1 repeat TMC PF07810.13 CCC69251.1 - 0.066 13.8 0.0 0.14 12.7 0.0 1.6 1 0 0 1 1 1 0 TMC domain Ribosomal_L10 PF00466.20 CCC69252.1 - 1.5e-10 41.1 0.0 2.3e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Methyltransf_4 PF02390.17 CCC69253.1 - 2e-62 209.7 0.1 2.9e-62 209.2 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 CCC69253.1 - 0.00025 21.7 0.0 0.001 19.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 CCC69253.1 - 0.00071 19.2 0.0 0.0038 16.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.12 CCC69253.1 - 0.0013 19.5 0.1 0.0045 17.7 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC69253.1 - 0.0024 17.7 0.1 0.0053 16.6 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC69253.1 - 0.085 13.5 0.0 0.73 10.5 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain DNA_binding_1 PF01035.20 CCC69254.1 - 3.9e-22 78.2 0.0 5.8e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Mito_carr PF00153.27 CCC69255.1 - 7.2e-32 109.2 0.1 1.9e-14 53.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein TRAF_BIRC3_bd PF16673.5 CCC69256.1 - 0.046 13.5 6.4 1.7 8.5 0.2 3.8 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain TUSC2 PF15000.6 CCC69256.1 - 0.072 13.4 1.1 0.6 10.4 1.1 2.7 1 0 0 1 1 1 0 Tumour suppressor candidate 2 Pox_A_type_inc PF04508.12 CCC69256.1 - 0.6 10.1 9.5 13 5.8 0.2 4.5 3 1 0 3 3 3 0 Viral A-type inclusion protein repeat VIT1 PF01988.19 CCC69259.1 - 1.1e-58 198.7 0.1 1.3e-58 198.4 0.1 1.1 1 0 0 1 1 1 1 VIT family DUF2207 PF09972.9 CCC69259.1 - 0.27 10.0 1.3 0.25 10.1 0.3 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Fun_ATP-synt_8 PF05933.13 CCC69259.1 - 0.48 10.6 3.8 1.4 9.1 3.3 2.0 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) DUF4199 PF13858.6 CCC69259.1 - 0.66 10.4 10.3 4.9 7.5 7.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) Rsa3 PF14615.6 CCC69260.1 - 5.2e-19 67.6 0.2 8.7e-19 66.8 0.2 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DUF966 PF06136.13 CCC69260.1 - 0.078 12.7 17.0 0.096 12.4 17.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF966) FAM76 PF16046.5 CCC69260.1 - 2.6 7.3 23.5 3.2 7.0 23.5 1.0 1 0 0 1 1 1 0 FAM76 protein Utp13 PF08625.11 CCC69261.1 - 3e-49 166.6 0.4 5.9e-49 165.6 0.4 1.5 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 CCC69261.1 - 1.3e-41 139.8 22.2 1.4e-06 28.9 0.0 10.5 11 0 0 11 11 11 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC69261.1 - 2.6e-15 56.5 2.7 0.012 15.9 0.0 6.6 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCC69261.1 - 4.2e-08 32.9 8.9 0.0051 16.2 0.3 4.7 4 1 1 5 5 5 3 WD40-like domain Nup160 PF11715.8 CCC69261.1 - 1.9e-05 23.5 6.3 1.5 7.3 0.0 5.3 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Hira PF07569.11 CCC69261.1 - 0.0031 17.2 1.5 0.49 10.1 0.2 4.2 3 1 1 4 4 4 1 TUP1-like enhancer of split DUF1699 PF08004.11 CCC69261.1 - 0.014 15.1 0.0 0.13 11.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1699) Ge1_WD40 PF16529.5 CCC69261.1 - 0.021 13.8 14.1 1.1 8.2 0.3 5.7 2 2 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Utp12 PF04003.12 CCC69261.1 - 0.051 13.9 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family PIP5K PF01504.18 CCC69262.1 - 1.1e-85 287.3 5.3 2.3e-85 286.2 5.3 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF5048 PF16467.5 CCC69262.1 - 0.05 13.9 0.0 0.14 12.5 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5048) Fungal_trans_2 PF11951.8 CCC69263.1 - 2.3e-12 46.5 0.2 2.3e-12 46.5 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC69263.1 - 5.7e-10 39.2 10.8 8.7e-10 38.6 10.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Activator_LAG-3 PF11498.8 CCC69263.1 - 1.6 7.6 33.5 1.1 8.2 0.3 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF16 PF01519.16 CCC69263.1 - 1.9 9.1 15.6 0.3 11.6 11.0 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 Nucleolin_bd PF16725.5 CCC69264.1 - 0.071 12.8 0.1 0.35 10.5 0.1 2.2 2 0 0 2 2 2 0 Nucleolin binding domain CRF1 PF10380.9 CCC69266.1 - 3.3e-35 120.8 3.9 3.3e-35 120.8 3.9 4.1 2 1 0 2 2 2 1 Transcription factor CRF1 EST1_DNA_bind PF10373.9 CCC69267.1 - 1.5e-34 119.8 8.5 4.9e-34 118.1 8.5 1.9 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 CCC69267.1 - 1e-10 42.4 0.2 4.5e-10 40.3 0.2 2.2 1 0 0 1 1 1 1 Telomerase activating protein Est1 Topoisom_bac PF01131.20 CCC69268.1 - 1.3e-101 340.6 0.0 1.1e-100 337.6 0.0 1.9 1 1 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 CCC69268.1 - 7.2e-22 77.6 0.0 1.9e-21 76.2 0.0 1.8 1 0 0 1 1 1 1 Toprim domain Transp_cyt_pur PF02133.15 CCC69269.1 - 3.2e-74 250.3 36.9 4.3e-74 249.9 36.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Gate PF07670.14 CCC69269.1 - 5.1 7.4 10.1 1.7 9.0 0.9 4.0 3 1 0 3 3 3 0 Nucleoside recognition Rogdi_lz PF10259.9 CCC69270.1 - 2.5e-64 217.3 2.2 2.8e-64 217.2 2.2 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein HSP9_HSP12 PF04119.12 CCC69270.1 - 0.032 14.6 1.1 0.067 13.6 1.1 1.5 1 0 0 1 1 1 0 Heat shock protein 9/12 YfkD PF14167.6 CCC69270.1 - 0.069 12.3 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 YfkD-like protein DpnI_C PF17726.1 CCC69270.1 - 0.94 9.7 0.0 0.94 9.7 0.0 2.8 4 0 0 4 4 4 0 Dam-replacing HTH domain FHA PF00498.26 CCC69271.1 - 5.6e-18 65.1 1.0 6.6e-16 58.4 0.5 3.2 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 CCC69271.1 - 2.5e-06 27.7 0.4 1.3e-05 25.4 0.0 2.4 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain TMPIT PF07851.13 CCC69271.1 - 1.1 8.5 7.0 2 7.6 7.0 1.4 1 0 0 1 1 1 0 TMPIT-like protein Mt_ATP-synt_D PF05873.12 CCC69271.1 - 2.4 8.0 7.8 0.44 10.4 3.2 2.0 2 1 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Exonuc_VII_L PF02601.15 CCC69271.1 - 6.8 6.2 13.1 2.2 7.8 10.2 1.6 2 0 0 2 2 2 0 Exonuclease VII, large subunit BPL_LplA_LipB PF03099.19 CCC69272.1 - 6.1e-20 71.5 0.0 1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PI3Ka PF00613.20 CCC69273.1 - 1.4e-73 246.3 1.6 2e-73 245.8 1.6 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 CCC69273.1 - 3.4e-52 177.7 0.0 1.9e-34 119.6 0.0 2.6 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 CCC69273.1 - 1.3e-25 90.0 1.5 2.5e-25 89.0 0.7 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 Kinesin PF00225.23 CCC69273.1 - 0.0015 17.5 0.8 0.0025 16.8 0.8 1.2 1 0 0 1 1 1 1 Kinesin motor domain RSN1_7TM PF02714.15 CCC69274.1 - 6.6e-82 274.9 23.6 6.6e-82 274.9 23.6 1.8 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 CCC69274.1 - 3.1e-38 131.0 2.2 3.1e-38 131.0 2.2 2.3 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 CCC69274.1 - 4.9e-33 114.8 0.0 8.6e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Arv1 PF04161.13 CCC69275.1 - 1e-63 215.3 21.4 1e-63 215.3 21.4 1.6 2 0 0 2 2 2 1 Arv1-like family ATP_bind_1 PF03029.17 CCC69276.1 - 2e-87 293.0 0.0 2.3e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 CCC69276.1 - 0.001 18.1 0.1 0.0028 16.7 0.0 1.6 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 CCC69276.1 - 0.0019 18.0 0.0 0.0065 16.3 0.0 1.9 3 0 0 3 3 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_10 PF12846.7 CCC69276.1 - 0.0043 16.0 0.0 0.0067 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain GTP_EFTU PF00009.27 CCC69276.1 - 0.0046 16.5 0.0 0.24 10.9 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCC69276.1 - 0.0075 16.2 0.2 0.067 13.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 CCC69276.1 - 0.0095 16.0 0.0 0.029 14.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 CCC69276.1 - 0.01 16.4 0.0 0.019 15.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF87 PF01935.17 CCC69276.1 - 0.01 15.9 0.0 0.023 14.8 0.0 1.7 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_18 PF13238.6 CCC69276.1 - 0.011 16.3 0.0 0.029 14.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CCC69276.1 - 0.012 16.0 0.0 0.033 14.6 0.0 1.8 2 0 0 2 2 1 0 RNA helicase AAA_7 PF12775.7 CCC69276.1 - 0.016 14.8 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 CCC69276.1 - 0.024 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein KAP_NTPase PF07693.14 CCC69276.1 - 0.026 13.8 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.6 CCC69276.1 - 0.041 13.6 0.0 0.069 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCC69276.1 - 0.052 13.3 0.0 0.098 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 CCC69276.1 - 0.06 12.5 0.5 0.17 11.0 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 CCC69276.1 - 0.061 13.7 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 CCC69276.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CCC69276.1 - 0.064 13.5 0.0 0.16 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 CCC69276.1 - 0.074 13.5 0.0 0.2 12.1 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CCC69276.1 - 0.075 13.4 0.0 0.19 12.1 0.0 1.6 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 CCC69276.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Septin PF00735.18 CCC69276.1 - 0.14 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Septin Sigma54_activat PF00158.26 CCC69276.1 - 0.15 11.8 0.0 0.23 11.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 CCC69276.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 CCC69276.1 - 0.16 11.7 0.0 0.37 10.5 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Dynamin_N PF00350.23 CCC69276.1 - 0.19 11.8 0.0 0.41 10.7 0.0 1.6 1 0 0 1 1 1 0 Dynamin family AIG1 PF04548.16 CCC69276.1 - 0.19 11.1 0.0 0.33 10.3 0.0 1.4 1 0 0 1 1 1 0 AIG1 family TIP49 PF06068.13 CCC69277.1 - 1e-169 564.3 0.5 1.3e-169 564.0 0.5 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CCC69277.1 - 3.1e-21 75.3 0.1 9.3e-21 73.7 0.1 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 CCC69277.1 - 1.7e-08 35.0 0.1 6.4e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCC69277.1 - 3.7e-07 30.0 0.1 0.0001 22.1 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CCC69277.1 - 0.0012 19.2 0.0 0.0024 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCC69277.1 - 0.004 17.5 0.6 3.9 7.8 0.2 2.4 2 0 0 2 2 2 2 AAA domain DnaB_C PF03796.15 CCC69277.1 - 0.018 14.4 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_16 PF13191.6 CCC69277.1 - 0.026 14.9 0.1 0.15 12.4 0.1 2.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 CCC69277.1 - 0.026 14.5 0.1 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCC69277.1 - 0.04 13.3 0.1 4.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CCC69277.1 - 0.046 13.8 0.0 0.82 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 CCC69277.1 - 0.051 13.3 0.0 6.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.12 CCC69277.1 - 0.056 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein DUF4295 PF14128.6 CCC69277.1 - 0.059 13.2 0.2 0.21 11.4 0.2 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) Zeta_toxin PF06414.12 CCC69277.1 - 0.078 12.2 0.1 0.19 11.0 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin Sec1 PF00995.23 CCC69278.1 - 1.6e-122 410.7 10.3 1.8e-122 410.5 10.3 1.0 1 0 0 1 1 1 1 Sec1 family KaiA PF07688.12 CCC69278.1 - 0.15 12.2 2.0 0.46 10.6 0.1 2.7 3 0 0 3 3 3 0 KaiA C-terminal domain Cpn60_TCP1 PF00118.24 CCC69279.1 - 1.9e-157 524.8 1.1 2.2e-157 524.7 1.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M24 PF00557.24 CCC69280.1 - 4.1e-52 176.9 0.1 5.6e-52 176.5 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 CCC69280.1 - 1.2e-16 60.7 6.9 1.2e-16 60.7 6.9 1.9 2 0 0 2 2 2 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 CCC69280.1 - 0.022 14.9 3.9 0.022 14.9 3.9 2.4 2 1 0 2 2 2 0 MYND finger ATP-cone PF03477.16 CCC69280.1 - 0.081 13.5 0.0 8.2 7.1 0.0 2.3 2 0 0 2 2 2 0 ATP cone domain dCMP_cyt_deam_1 PF00383.23 CCC69281.1 - 5.2e-16 58.4 0.3 6.3e-16 58.1 0.3 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 CCC69281.1 - 1.4e-13 51.2 0.2 1.1e-10 41.9 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 CCC69281.1 - 0.00052 19.7 0.7 0.34 10.5 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases DHHC PF01529.20 CCC69282.1 - 9.1e-32 110.0 12.8 9.1e-32 110.0 12.8 2.5 2 1 0 2 2 2 1 DHHC palmitoyltransferase MENTAL PF10457.9 CCC69282.1 - 0.019 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Cholesterol-capturing domain DUF3781 PF12636.7 CCC69282.1 - 0.082 12.8 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3781) DUF2207 PF09972.9 CCC69282.1 - 0.25 10.1 1.7 5 5.8 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PRELI PF04707.14 CCC69283.1 - 2.1e-54 183.6 0.1 4.6e-54 182.5 0.0 1.5 1 1 1 2 2 2 1 PRELI-like family COG2 PF06148.11 CCC69283.1 - 0.053 13.6 0.1 0.092 12.8 0.1 1.6 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 ubiquitin PF00240.23 CCC69284.1 - 4.2e-34 116.1 0.6 7.7e-34 115.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.19 CCC69284.1 - 1.2e-22 79.7 4.3 1.2e-22 79.7 4.3 1.8 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 CCC69284.1 - 4.7e-16 58.4 0.7 4.7e-16 58.4 0.7 1.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCC69284.1 - 2.6e-05 24.6 0.3 0.00012 22.4 0.1 2.1 2 1 0 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCC69284.1 - 0.0013 18.9 0.6 0.0029 17.7 0.6 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CCC69284.1 - 0.0035 17.6 0.4 0.0077 16.6 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CCC69284.1 - 0.0054 16.6 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 CCC69284.1 - 0.012 16.1 0.3 0.017 15.7 0.3 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 CCC69284.1 - 0.019 15.0 1.0 5.7 7.1 0.2 2.4 2 0 0 2 2 2 0 Ubiquitin-like domain zinc_ribbon_5 PF13719.6 CCC69284.1 - 1.6 8.5 4.7 1.1 9.0 0.1 2.5 2 0 0 2 2 2 0 zinc-ribbon domain Sec10 PF07393.11 CCC69285.1 - 3.4e-195 650.5 24.3 3.4e-195 650.5 24.3 1.3 2 0 0 2 2 2 1 Exocyst complex component Sec10 Vps51 PF08700.11 CCC69285.1 - 0.032 14.3 4.9 0.13 12.3 3.6 2.9 2 0 0 2 2 2 0 Vps51/Vps67 DUF1664 PF07889.12 CCC69285.1 - 0.51 10.4 6.0 0.33 11.0 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 CCC69285.1 - 0.92 9.6 11.5 0.061 13.3 1.7 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Snapin_Pallidin PF14712.6 CCC69285.1 - 2.5 8.6 9.8 1.1 9.7 6.0 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Com_YlbF PF06133.11 CCC69285.1 - 3.8 8.2 13.2 13 6.4 4.8 3.4 1 1 2 3 3 3 0 Control of competence regulator ComK, YlbF/YmcA PseudoU_synth_2 PF00849.22 CCC69286.1 - 4.3e-19 69.2 0.0 7.7e-19 68.3 0.0 1.4 1 1 0 1 1 1 1 RNA pseudouridylate synthase Peptidase_M16 PF00675.20 CCC69287.1 - 4.8e-52 175.9 0.0 1.2e-51 174.6 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCC69287.1 - 4.1e-37 128.0 0.0 5.4e-36 124.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain M16C_assoc PF08367.11 CCC69287.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase M16C associated BHD_3 PF10405.9 CCC69288.1 - 2.7e-11 43.7 0.4 6e-11 42.6 0.4 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.9 CCC69288.1 - 1.2e-09 37.9 0.0 2.9e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.15 CCC69288.1 - 1.3e-09 37.9 1.2 3.7e-09 36.4 0.4 2.2 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 CCC69288.1 - 0.086 13.8 2.4 0.12 13.3 0.2 2.4 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 DUF3899 PF13038.6 CCC69288.1 - 0.4 11.2 1.8 16 6.1 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) Sugar_tr PF00083.24 CCC69289.1 - 3.6e-168 560.1 31.0 4.2e-168 559.9 31.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC69289.1 - 3.4e-27 95.3 26.6 2.1e-26 92.7 18.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 CCC69289.1 - 1.6 9.1 7.4 0.54 10.6 0.2 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) DUF2530 PF10745.9 CCC69289.1 - 3.1 8.1 6.6 1.2 9.5 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) GST_N PF02798.20 CCC69290.1 - 1.4e-14 54.2 0.0 2.7e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 CCC69290.1 - 1.6e-12 47.5 0.0 3.4e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCC69290.1 - 2.6e-07 31.0 0.0 4.8e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CCC69290.1 - 3.2e-06 27.3 0.0 1.2e-05 25.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCC69290.1 - 0.0002 21.3 0.0 0.00037 20.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CCC69290.1 - 0.0022 18.3 0.0 0.0038 17.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF21 PF01595.20 CCC69291.1 - 1.2e-34 119.6 0.1 2.1e-34 118.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 CCC69291.1 - 0.0003 21.2 0.0 0.38 11.2 0.0 2.7 2 0 0 2 2 2 2 CBS domain Sec16 PF12932.7 CCC69291.1 - 0.22 12.1 1.1 0.77 10.4 0.5 2.2 1 1 1 2 2 2 0 Vesicle coat trafficking protein Sec16 mid-region ADH_N PF08240.12 CCC69292.1 - 2.7e-26 91.6 2.9 4.5e-26 90.9 2.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCC69292.1 - 6.1e-19 68.3 0.0 9.6e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CCC69292.1 - 3.9e-06 26.3 0.4 1.6e-05 24.4 0.3 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCC69292.1 - 0.00043 19.6 0.0 0.00068 19.0 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CCC69292.1 - 0.063 13.7 0.0 0.11 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DUP PF00674.18 CCC69293.1 - 8.8e-15 54.7 1.6 1.1e-13 51.2 0.4 2.2 2 0 0 2 2 2 1 DUP family AgrB PF04647.15 CCC69293.1 - 0.025 13.9 4.5 0.083 12.2 0.5 2.2 2 0 0 2 2 2 0 Accessory gene regulator B AMP-binding PF00501.28 CCC69294.1 - 1.5e-85 287.3 0.0 2e-85 287.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 CCC69294.1 - 4.1e-20 71.4 0.5 8.5e-20 70.4 0.5 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 CCC69294.1 - 7.1e-20 71.8 0.0 1.8e-19 70.5 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain NUDIX PF00293.28 CCC69295.1 - 2.9e-13 50.0 0.0 1e-12 48.2 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain Stb3 PF10330.9 CCC69296.1 - 1.6e-30 105.0 0.0 2.9e-30 104.2 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein DUF2415 PF10313.9 CCC69297.1 - 1.3e-20 73.1 0.8 4.3e-20 71.4 0.6 2.1 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Str_synth PF03088.16 CCC69297.1 - 0.023 14.8 0.0 0.079 13.1 0.0 1.9 1 0 0 1 1 1 0 Strictosidine synthase Pep3_Vps18 PF05131.14 CCC69298.1 - 3.7e-41 140.4 0.8 3.7e-41 140.4 0.8 2.5 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 CCC69298.1 - 4.1e-08 33.2 5.1 4.1e-08 33.2 5.1 2.9 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 CCC69298.1 - 6.2e-05 23.4 1.0 6.2e-05 23.4 1.0 2.9 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 2 zf-RING_UBOX PF13445.6 CCC69298.1 - 0.0036 17.3 3.4 0.01 15.8 3.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CCC69298.1 - 0.0053 17.1 4.6 0.0053 17.1 4.6 2.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 CCC69298.1 - 0.01 15.6 4.9 0.032 14.1 4.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCC69298.1 - 0.014 15.1 4.7 0.058 13.2 4.7 2.1 1 0 0 1 1 1 0 RING-like zinc finger zf-rbx1 PF12678.7 CCC69298.1 - 0.13 12.6 1.6 0.53 10.6 1.6 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 CCC69298.1 - 0.44 10.5 4.3 1.6 8.6 4.3 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCC69298.1 - 0.58 10.2 13.6 1.9 8.5 13.6 2.0 1 1 0 1 1 1 0 zinc-RING finger domain LSM PF01423.22 CCC69299.1 - 5.3e-17 61.3 0.6 6.6e-17 61.0 0.6 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 CCC69299.1 - 0.043 14.0 0.1 0.071 13.3 0.1 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain EF-hand_4 PF12763.7 CCC69300.1 - 0.013 15.4 0.1 0.015 15.2 0.1 1.0 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Orthopox_F14 PF06076.12 CCC69300.1 - 0.034 14.4 0.1 0.039 14.2 0.1 1.2 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Spermine_synth PF01564.17 CCC69301.1 - 6.2e-66 221.4 0.4 1e-65 220.7 0.4 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CCC69301.1 - 2e-20 72.4 0.1 4.2e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_31 PF13847.6 CCC69301.1 - 0.00046 20.0 0.0 0.00061 19.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCC69301.1 - 0.0033 18.1 0.1 0.0077 16.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 CCC69301.1 - 0.009 15.3 0.0 0.013 14.7 0.0 1.2 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Pyr_redox_2 PF07992.14 CCC69301.1 - 0.019 14.2 0.1 0.026 13.8 0.1 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_3 PF01596.17 CCC69301.1 - 0.023 13.9 0.1 0.036 13.2 0.1 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_23 PF13489.6 CCC69301.1 - 0.058 13.2 0.0 0.095 12.5 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 CCC69301.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 CCC69301.1 - 0.11 13.3 0.1 0.3 11.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 CCC69301.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain DUF4477 PF14780.6 CCC69302.1 - 0.022 14.4 6.5 0.088 12.4 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4477) LYRIC PF15686.5 CCC69302.1 - 0.41 10.2 10.3 0.53 9.8 10.3 1.1 1 0 0 1 1 1 0 Lysine-rich CEACAM1 co-isolated protein family Glyco_hydro81C PF17652.1 CCC69303.1 - 3e-154 513.5 6.9 4e-154 513.0 6.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 C-terminal domain Glyco_hydro_81 PF03639.13 CCC69303.1 - 2.5e-92 309.5 0.3 3.7e-92 308.9 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 N-terminal domain Pro_dh PF01619.18 CCC69306.1 - 1.2e-55 189.2 0.0 1.5e-55 188.8 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase SLS PF14611.6 CCC69308.1 - 2e-57 194.6 7.3 4.6e-57 193.4 6.4 2.2 2 0 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator SR-25 PF10500.9 CCC69308.1 - 0.0094 15.6 11.8 0.0094 15.6 11.8 1.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein DUF3446 PF11928.8 CCC69308.1 - 0.59 10.5 12.7 0.49 10.7 8.6 2.6 2 0 0 2 2 2 0 Early growth response N-terminal domain bZIP_C PF12498.8 CCC69308.1 - 3.7 8.5 6.8 2.8 8.9 3.9 2.4 2 0 0 2 2 2 0 Basic leucine-zipper C terminal IMUP PF15761.5 CCC69308.1 - 4.4 8.1 8.5 10 6.9 8.5 1.6 1 0 0 1 1 1 0 Immortalisation up-regulated protein Na_H_Exchanger PF00999.21 CCC69309.1 - 4.4e-90 302.2 28.3 5.3e-90 302.0 28.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.10 CCC69309.1 - 2.8e-73 247.7 56.6 1.5e-62 212.4 35.7 2.7 1 1 2 3 3 3 2 Alkali metal cation/H+ antiporter Nha1 C terminus MarC PF01914.17 CCC69309.1 - 0.11 11.9 2.4 2.4 7.5 0.8 2.6 2 0 0 2 2 2 0 MarC family integral membrane protein Methyltransf_16 PF10294.9 CCC69310.1 - 1.4e-08 34.7 1.6 0.0013 18.5 0.2 2.1 1 1 1 2 2 2 2 Lysine methyltransferase Slx4 PF09494.10 CCC69311.1 - 8.1e-16 57.7 0.2 1.7e-15 56.7 0.2 1.6 1 0 0 1 1 1 1 Slx4 endonuclease Choline_kinase PF01633.20 CCC69312.1 - 1.5e-65 220.8 0.0 2.3e-65 220.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.14 CCC69312.1 - 2.6e-13 49.4 1.5 4.8e-13 48.6 0.1 2.1 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.23 CCC69312.1 - 2e-05 24.7 0.0 0.025 14.5 0.0 2.4 2 1 0 2 2 2 2 Phosphotransferase enzyme family HVSL PF09749.9 CCC69313.1 - 2.1e-23 83.1 0.2 2.5e-23 82.8 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 CCC69313.1 - 0.00084 19.3 0.2 0.0014 18.5 0.2 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily GspL_C PF12693.7 CCC69313.1 - 0.073 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 GspL periplasmic domain zf-C2H2 PF00096.26 CCC69314.1 - 2.8e-09 36.9 7.0 0.00011 22.4 0.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC69314.1 - 8.4e-05 23.1 5.3 0.21 12.5 0.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCC69314.1 - 0.003 17.9 6.6 0.0064 16.9 0.1 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-TRAF PF02176.18 CCC69314.1 - 0.045 14.5 0.8 0.081 13.6 0.8 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger FOXP-CC PF16159.5 CCC69314.1 - 0.055 14.1 0.3 0.055 14.1 0.3 3.2 2 1 1 3 3 3 0 FOXP coiled-coil domain Acyl_transf_2 PF02273.15 CCC69314.1 - 0.1 11.8 0.7 0.16 11.2 0.7 1.2 1 0 0 1 1 1 0 Acyl transferase zf-C2H2_jaz PF12171.8 CCC69314.1 - 0.4 11.0 2.9 16 5.9 0.6 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AAA_23 PF13476.6 CCC69314.1 - 1.3 9.5 11.1 3.2 8.2 7.6 2.3 2 0 0 2 2 2 0 AAA domain Zip PF02535.22 CCC69315.1 - 2.2e-86 290.1 1.4 2.7e-86 289.8 1.4 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter MAP17 PF15807.5 CCC69315.1 - 0.58 10.4 1.5 41 4.4 0.1 2.7 2 1 1 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 WD40 PF00400.32 CCC69316.1 - 2.5e-46 154.7 34.9 4.7e-06 27.2 0.1 11.3 11 1 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.12 CCC69316.1 - 2.4e-19 69.6 0.3 4.2e-19 68.8 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 CCC69316.1 - 1.6e-14 53.9 7.5 0.002 18.4 0.0 7.9 5 3 5 10 10 10 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCC69316.1 - 1.5e-07 31.1 10.7 2.4e-05 23.8 0.1 4.4 4 0 0 4 4 4 3 WD40-like domain Nup160 PF11715.8 CCC69316.1 - 2e-05 23.5 8.9 0.03 13.0 0.0 5.1 3 2 1 5 5 5 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCC69316.1 - 0.0067 15.4 10.8 2.5 7.0 0.0 6.0 3 3 2 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 CCC69316.1 - 0.0082 15.9 1.9 5.8 6.6 0.0 4.2 4 1 0 4 4 4 1 TUP1-like enhancer of split eIF2A PF08662.11 CCC69316.1 - 0.0092 15.9 0.2 0.6 10.0 0.0 3.8 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A ELYS-bb PF16687.5 CCC69316.1 - 0.018 13.7 0.0 0.3 9.7 0.0 2.3 2 0 0 2 2 2 0 beta-propeller of ELYS nucleoporin Nkap_C PF06047.11 CCC69316.1 - 0.27 11.4 1.0 0.88 9.7 0.2 2.2 2 0 0 2 2 2 0 NF-kappa-B-activating protein C-terminal domain Cullin_binding PF03556.15 CCC69317.1 - 1e-27 96.9 4.5 1.5e-27 96.4 4.5 1.2 1 0 0 1 1 1 1 Cullin binding ANAPC2 PF08672.11 CCC69318.1 - 2.6e-18 66.3 4.4 3.6e-17 62.6 0.1 3.9 4 0 0 4 4 4 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.10 CCC69318.1 - 0.011 15.8 0.1 0.034 14.2 0.0 1.8 2 0 0 2 2 2 0 FeoC like transcriptional regulator DUF746 PF05344.11 CCC69318.1 - 0.039 13.8 0.0 9 6.2 0.0 3.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) GATase PF00117.28 CCC69319.1 - 2.5e-13 50.2 0.0 3.3e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CCC69319.1 - 0.0011 18.8 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 DUF1655 PF07868.11 CCC69319.1 - 0.12 12.5 0.0 0.83 9.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1655) STb_secrete PF09075.10 CCC69319.1 - 0.18 11.9 0.7 0.37 10.9 0.7 1.5 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory Asp PF00026.23 CCC69320.1 - 1.7e-76 257.6 12.4 1.7e-76 257.6 12.4 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCC69320.1 - 3.6e-10 40.4 1.7 3.6e-10 40.4 1.7 3.0 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TMEM154 PF15102.6 CCC69320.1 - 0.019 14.9 4.3 0.047 13.6 4.3 1.8 1 0 0 1 1 1 0 TMEM154 protein family TAXi_C PF14541.6 CCC69320.1 - 0.086 12.6 0.6 1.5 8.6 0.3 3.0 3 1 0 3 3 3 0 Xylanase inhibitor C-terminal zf-RING_2 PF13639.6 CCC69321.1 - 2.1e-09 37.5 8.9 4.1e-08 33.4 5.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 CCC69321.1 - 2.6e-06 27.6 2.5 2.6e-06 27.6 2.5 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 CCC69321.1 - 6.8e-06 25.9 2.6 1.6e-05 24.6 2.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CCC69321.1 - 0.00016 21.4 6.0 0.00022 21.0 3.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC69321.1 - 0.00019 21.4 9.0 0.0023 17.9 4.9 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CCC69321.1 - 0.00025 20.8 4.9 0.00025 20.8 4.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCC69321.1 - 0.00065 19.8 3.7 0.00065 19.8 3.7 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 CCC69321.1 - 0.0021 17.9 7.9 0.0037 17.1 3.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCC69321.1 - 0.0021 18.0 6.4 0.056 13.4 3.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 CCC69321.1 - 0.02 14.6 1.5 1.9 8.3 0.2 2.5 2 0 0 2 2 2 0 RING-like zinc finger zf-ANAPC11 PF12861.7 CCC69321.1 - 0.063 13.3 1.0 0.17 11.9 1.0 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 CCC69321.1 - 0.15 12.2 1.9 0.32 11.2 1.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 Orf78 PF06024.12 CCC69321.1 - 0.17 12.2 0.2 0.17 12.2 0.2 3.5 3 0 0 3 3 3 0 Orf78 (ac78) Mod_r PF07200.13 CCC69322.1 - 1.6e-21 76.9 19.9 1.9e-21 76.7 19.9 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein CREPT PF16566.5 CCC69322.1 - 0.0019 18.4 0.9 0.0019 18.4 0.9 2.3 2 0 0 2 2 2 1 Cell-cycle alteration and expression-elevated protein in tumour DUF724 PF05266.14 CCC69322.1 - 0.0022 17.8 3.6 0.0022 17.8 3.6 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF724) DUF2959 PF11172.8 CCC69322.1 - 0.0025 18.0 4.9 0.0033 17.6 4.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) Trimer_CC PF08954.11 CCC69322.1 - 0.0044 16.6 3.2 0.013 15.1 3.2 1.8 1 0 0 1 1 1 1 Trimerisation motif CENP-F_leu_zip PF10473.9 CCC69322.1 - 0.0063 16.5 15.0 0.053 13.5 6.8 2.3 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AKNA PF12443.8 CCC69322.1 - 0.0097 16.5 5.2 0.0097 16.5 5.2 2.4 2 1 0 2 2 2 1 AT-hook-containing transcription factor 4HB_MCP_1 PF12729.7 CCC69322.1 - 0.043 13.3 6.1 0.054 13.0 5.6 1.5 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction Seryl_tRNA_N PF02403.22 CCC69322.1 - 0.046 13.9 8.7 0.095 12.9 6.5 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain kleA_kleC PF17383.2 CCC69322.1 - 0.05 13.9 1.2 0.081 13.3 0.3 1.9 2 0 0 2 2 1 0 Uncharacterized KorC regulated protein A Spc7 PF08317.11 CCC69322.1 - 0.067 12.1 12.9 0.11 11.3 12.3 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein H-kinase_dim PF02895.14 CCC69322.1 - 0.093 13.1 0.9 0.093 13.1 0.9 2.1 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain NPV_P10 PF05531.12 CCC69322.1 - 0.13 12.8 4.0 0.48 10.9 0.3 2.4 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5344 PF17279.2 CCC69322.1 - 0.14 12.8 5.4 0.22 12.1 2.6 2.4 2 1 1 3 3 2 0 Family of unknown function (DUF5344) CLZ PF16526.5 CCC69322.1 - 0.14 12.5 9.1 0.55 10.6 3.6 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CotJB PF12652.7 CCC69322.1 - 0.14 12.4 3.0 2.9 8.2 0.1 3.1 2 1 0 2 2 2 0 CotJB protein V_ATPase_I PF01496.19 CCC69322.1 - 0.21 9.5 5.6 0.29 9.0 5.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF5082 PF16888.5 CCC69322.1 - 0.21 11.8 10.1 0.56 10.5 10.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) DivIC PF04977.15 CCC69322.1 - 0.23 11.2 10.8 0.33 10.7 6.6 2.8 1 1 1 2 2 2 0 Septum formation initiator COG2 PF06148.11 CCC69322.1 - 0.24 11.5 8.2 7.9 6.6 6.6 2.3 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Spc24 PF08286.11 CCC69322.1 - 0.27 11.5 13.1 11 6.4 13.1 2.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 ZapB PF06005.12 CCC69322.1 - 0.36 11.3 18.5 3.9 8.0 18.5 2.4 1 1 0 1 1 1 0 Cell division protein ZapB Prefoldin PF02996.17 CCC69322.1 - 0.45 10.4 9.8 0.34 10.8 2.2 2.9 1 1 2 3 3 3 0 Prefoldin subunit PCRF PF03462.18 CCC69322.1 - 0.57 10.0 9.0 2.2 8.1 2.7 2.0 1 1 1 2 2 2 0 PCRF domain YabA PF06156.13 CCC69322.1 - 0.69 10.6 12.5 5.3 7.7 12.5 2.2 1 1 0 1 1 1 0 Initiation control protein YabA YlqD PF11068.8 CCC69322.1 - 0.79 10.1 15.4 0.19 12.1 2.0 2.3 1 1 1 2 2 2 0 YlqD protein TMF_TATA_bd PF12325.8 CCC69322.1 - 0.8 9.9 16.3 0.84 9.9 8.7 2.3 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0242 PF06785.11 CCC69322.1 - 0.97 9.5 17.7 0.93 9.6 16.1 1.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4140 PF13600.6 CCC69322.1 - 1 9.9 6.1 0.47 10.9 2.0 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) TMF_DNA_bd PF12329.8 CCC69322.1 - 1 9.4 10.7 0.094 12.7 3.6 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.13 CCC69322.1 - 1.2 8.3 9.0 1.6 7.9 9.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Swi5 PF07061.11 CCC69322.1 - 1.4 9.1 11.6 7.6 6.7 7.3 2.6 1 1 1 2 2 2 0 Swi5 Occludin_ELL PF07303.13 CCC69322.1 - 1.8 9.3 13.4 2.8 8.7 7.7 2.3 1 1 1 2 2 2 0 Occludin homology domain SpoOE-like PF09388.10 CCC69322.1 - 1.9 8.4 11.0 0.11 12.4 2.6 2.9 3 0 0 3 3 2 0 Spo0E like sporulation regulatory protein Fzo_mitofusin PF04799.13 CCC69322.1 - 2 8.0 8.1 1.4 8.5 2.2 2.1 2 0 0 2 2 2 0 fzo-like conserved region DUF1664 PF07889.12 CCC69322.1 - 2.2 8.3 6.5 7.4 6.6 5.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 CCC69322.1 - 2.4 8.7 21.7 4.8 7.7 17.8 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Laminin_II PF06009.12 CCC69322.1 - 2.9 7.9 7.2 3.1 7.8 1.1 2.2 1 1 1 2 2 2 0 Laminin Domain II FlxA PF14282.6 CCC69322.1 - 3.4 7.7 15.2 4.8 7.2 6.8 2.3 1 1 0 2 2 2 0 FlxA-like protein Cep57_MT_bd PF06657.13 CCC69322.1 - 4.3 7.9 13.8 2.3 8.7 6.9 2.5 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 MciZ PF13072.6 CCC69322.1 - 6.3 6.7 5.6 14 5.6 0.4 3.5 4 0 0 4 4 4 0 Mother cell inhibitor of FtsZ FapA PF03961.13 CCC69322.1 - 6.5 5.2 10.3 13 4.2 10.3 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A zf-C4H2 PF10146.9 CCC69322.1 - 7.1 6.9 11.9 10 6.4 11.9 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein DUF641 PF04859.12 CCC69322.1 - 7.6 6.9 10.3 1.2 9.5 3.8 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) HR1 PF02185.16 CCC69322.1 - 7.6 6.7 13.5 2.2 8.5 3.9 2.6 2 1 0 2 2 2 0 Hr1 repeat FlaC_arch PF05377.11 CCC69322.1 - 8.4 6.9 8.0 5 7.6 4.6 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.21 CCC69322.1 - 8.6 6.5 12.0 2.3 8.4 4.6 3.1 1 1 3 4 4 3 0 bZIP transcription factor ACCA PF03255.14 CCC69322.1 - 8.8 6.2 9.0 1.8 8.4 3.8 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Abhydrolase_2 PF02230.16 CCC69323.1 - 5.8e-54 183.2 0.1 6.4e-54 183.0 0.1 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 CCC69323.1 - 1.1e-09 38.2 0.1 7.7e-09 35.5 0.1 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 CCC69323.1 - 0.0014 18.1 1.0 1 8.8 0.0 2.8 2 1 1 3 3 3 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 CCC69323.1 - 0.0039 16.5 0.5 2.7 7.2 0.0 3.0 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCC69323.1 - 0.02 15.5 0.0 0.023 15.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCC69323.1 - 0.14 11.8 0.2 14 5.3 0.0 2.4 2 1 0 2 2 2 0 alpha/beta hydrolase fold tRNA-synt_1e PF01406.19 CCC69323.1 - 0.16 11.3 0.1 0.22 10.8 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain TPR_14 PF13428.6 CCC69324.1 - 6.2e-19 67.1 0.0 0.0025 18.5 0.0 9.2 7 2 3 10 10 10 4 Tetratricopeptide repeat HAT PF02184.16 CCC69324.1 - 7.4e-13 48.2 34.7 4e-05 23.5 0.5 9.6 10 0 0 10 10 10 4 HAT (Half-A-TPR) repeat TPR_19 PF14559.6 CCC69324.1 - 2.9e-09 37.3 0.1 0.0052 17.3 0.0 5.7 6 1 2 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCC69324.1 - 1.4e-06 28.3 1.5 0.00027 21.1 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat U3_assoc_6 PF08640.11 CCC69324.1 - 0.00035 20.6 19.5 0.076 13.1 1.0 6.4 4 3 2 6 6 6 2 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.17 CCC69324.1 - 0.008 16.2 6.9 48 4.4 0.0 6.7 9 0 0 9 9 9 0 Tetratricopeptide repeat NRDE-2 PF08424.10 CCC69324.1 - 0.017 14.3 24.6 0.38 9.8 2.7 5.4 3 3 2 5 5 5 0 NRDE-2, necessary for RNA interference TPR_6 PF13174.6 CCC69324.1 - 0.11 13.2 8.0 8.7 7.2 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCC69324.1 - 0.47 10.6 2.6 19 5.5 0.0 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat EF-hand_7 PF13499.6 CCC69324.1 - 0.81 10.2 4.6 99 3.5 4.6 3.0 1 1 0 1 1 1 0 EF-hand domain pair SF1-HH PF16275.5 CCC69325.1 - 1.2e-36 125.5 1.1 1.2e-36 125.5 1.1 2.0 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 CCC69325.1 - 3.1e-07 30.1 0.1 6.2e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 CCC69325.1 - 8.6e-06 25.6 9.6 7e-05 22.7 0.9 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 CCC69325.1 - 0.016 15.1 9.3 0.13 12.3 3.1 2.5 1 1 1 2 2 2 0 Zinc knuckle Prim_Zn_Ribbon PF08273.12 CCC69325.1 - 0.1 12.9 4.0 0.26 11.6 4.0 1.7 1 0 0 1 1 1 0 Zinc-binding domain of primase-helicase zf-CCHC_4 PF14392.6 CCC69325.1 - 0.17 11.7 6.6 3.3 7.5 0.2 2.4 2 0 0 2 2 2 0 Zinc knuckle PHD_4 PF16866.5 CCC69325.1 - 0.26 11.4 1.9 0.59 10.3 1.9 1.5 1 0 0 1 1 1 0 PHD-finger Lar_restr_allev PF14354.6 CCC69325.1 - 0.38 11.2 8.1 0.095 13.1 4.9 1.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar zf-CCHC_6 PF15288.6 CCC69325.1 - 1.4 8.8 8.5 4.2 7.3 2.1 2.9 1 1 1 2 2 2 0 Zinc knuckle Lactamase_B_6 PF16661.5 CCC69326.1 - 1e-76 256.7 0.2 2.7e-76 255.3 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain CPSF100_C PF13299.6 CCC69326.1 - 4e-21 75.9 0.6 1.5e-18 67.6 0.2 4.1 3 2 1 4 4 4 2 Cleavage and polyadenylation factor 2 C-terminal Avl9 PF09794.9 CCC69327.1 - 2.3e-150 500.5 0.2 3.9e-150 499.8 0.2 1.4 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.10 CCC69327.1 - 5.7e-10 39.2 0.2 1.2e-07 31.7 0.2 2.8 1 1 0 1 1 1 1 Stabilization of polarity axis DUF2347 PF09804.9 CCC69327.1 - 4.4e-05 23.2 11.8 0.0069 16.0 0.2 3.8 4 1 0 4 4 4 2 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 CCC69327.1 - 0.011 15.7 1.4 0.28 11.1 0.2 2.9 2 1 0 3 3 3 0 DENN (AEX-3) domain Hormone_recep PF00104.30 CCC69327.1 - 0.07 12.7 1.5 0.19 11.3 1.5 1.7 1 0 0 1 1 1 0 Ligand-binding domain of nuclear hormone receptor DUF4794 PF16042.5 CCC69327.1 - 0.11 13.5 0.3 0.11 13.5 0.3 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4794) Pkinase PF00069.25 CCC69328.1 - 1.5e-66 224.5 0.0 2.3e-66 223.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69328.1 - 8.5e-31 107.2 0.0 1.2e-30 106.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCC69328.1 - 2.2e-06 26.9 0.1 2.9e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CCC69328.1 - 0.00014 21.3 0.2 0.00048 19.5 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCC69328.1 - 0.0011 18.9 0.4 0.0054 16.7 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Ribosomal_60s PF00428.19 CCC69328.1 - 0.023 15.3 0.6 0.073 13.7 0.6 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Kinase-like PF14531.6 CCC69328.1 - 0.048 13.0 0.0 0.48 9.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like FTA2 PF13095.6 CCC69328.1 - 0.096 12.3 1.2 0.097 12.3 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CCC69328.1 - 0.11 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Secretin_N_2 PF07655.13 CCC69328.1 - 1.3 9.6 9.3 2.3 8.8 9.3 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain BAF1_ABF1 PF04684.13 CCC69328.1 - 4.3 6.3 13.9 5.6 5.9 13.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Flocculin_t3 PF13928.6 CCC69329.1 - 1.4e-15 57.5 17.4 1.4e-15 57.5 17.4 3.3 3 0 0 3 3 3 1 Flocculin type 3 repeat RIFIN PF02009.16 CCC69329.1 - 0.94 9.3 4.6 0.92 9.3 4.6 1.0 1 0 0 1 1 1 0 Rifin Redoxin PF08534.10 CCC69330.1 - 1.4e-28 99.5 0.3 1.6e-28 99.3 0.3 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 CCC69330.1 - 1.9e-06 27.8 0.1 2.7e-06 27.3 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF1462 PF07315.11 CCC69330.1 - 0.017 15.3 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) BTB_2 PF02214.22 CCC69331.1 - 7.5e-09 35.8 2.1 0.0003 21.1 0.3 2.9 2 1 0 2 2 2 2 BTB/POZ domain Asp4 PF16996.5 CCC69331.1 - 0.16 11.8 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 CHORD PF04968.12 CCC69332.1 - 0.0017 19.0 4.3 0.0042 17.8 4.3 1.7 1 0 0 1 1 1 1 CHORD DNA_pol_A_exo1 PF01612.20 CCC69332.1 - 0.012 15.4 0.6 0.056 13.1 0.2 2.4 2 1 0 2 2 2 0 3'-5' exonuclease KIX_2 PF16987.5 CCC69332.1 - 0.013 15.4 0.0 0.041 13.9 0.0 1.8 1 0 0 1 1 1 0 KIX domain AAA_5 PF07728.14 CCC69333.1 - 7.2e-126 414.8 1.4 7.8e-21 74.5 0.0 9.8 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 CCC69333.1 - 2.2e-51 172.5 0.6 2.7e-21 75.8 0.0 5.3 4 0 0 4 4 4 3 Midasin AAA lid domain AAA_3 PF07726.11 CCC69333.1 - 9.2e-33 112.9 0.0 1.6e-10 40.9 0.0 8.1 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 CCC69333.1 - 5.2e-32 110.1 0.0 4.4e-30 103.9 0.0 3.5 2 0 0 2 2 2 1 Midasin AAA lid domain AAA_7 PF12775.7 CCC69333.1 - 2.4e-28 98.9 12.0 3.2e-06 26.8 1.3 7.5 7 0 0 7 7 7 6 P-loop containing dynein motor region AAA PF00004.29 CCC69333.1 - 3.1e-25 89.1 4.1 6.5e-05 23.4 0.1 7.8 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) Dynein_heavy PF03028.15 CCC69333.1 - 3.9e-22 78.6 0.0 2e-05 24.6 0.0 8.3 8 0 0 8 8 8 4 Dynein heavy chain region D6 P-loop domain AAA_16 PF13191.6 CCC69333.1 - 2.4e-20 73.6 12.6 0.0032 17.9 0.9 8.9 7 2 0 7 7 6 5 AAA ATPase domain Sigma54_activat PF00158.26 CCC69333.1 - 9.9e-19 67.7 0.1 0.007 16.1 0.0 6.5 6 0 0 6 6 5 5 Sigma-54 interaction domain AAA_6 PF12774.7 CCC69333.1 - 1.7e-18 66.7 3.6 0.0028 16.7 0.0 9.3 10 1 1 11 11 11 4 Hydrolytic ATP binding site of dynein motor region AAA_18 PF13238.6 CCC69333.1 - 9.4e-16 58.5 4.3 0.032 14.8 0.1 8.2 7 0 0 7 7 6 3 AAA domain AAA_30 PF13604.6 CCC69333.1 - 2e-14 53.8 0.0 0.033 13.9 0.0 7.2 7 1 0 7 7 6 2 AAA domain T2SSE PF00437.20 CCC69333.1 - 6.6e-14 51.6 4.3 0.089 11.8 0.3 6.3 6 0 0 6 6 6 3 Type II/IV secretion system protein TsaE PF02367.17 CCC69333.1 - 8.4e-14 51.6 7.6 0.038 14.0 0.1 6.6 7 0 0 7 7 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activ_2 PF14532.6 CCC69333.1 - 8.7e-13 48.6 0.3 0.017 15.3 0.0 6.2 6 0 0 6 6 5 2 Sigma-54 interaction domain AAA_14 PF13173.6 CCC69333.1 - 1.7e-12 47.5 6.4 0.013 15.6 0.0 9.0 10 0 0 10 10 8 1 AAA domain AAA_22 PF13401.6 CCC69333.1 - 2.4e-12 47.3 5.7 0.097 12.9 0.3 7.7 6 1 1 7 7 6 2 AAA domain RsgA_GTPase PF03193.16 CCC69333.1 - 1.9e-11 44.1 5.7 0.049 13.5 0.4 6.0 6 0 0 6 6 5 3 RsgA GTPase ABC_tran PF00005.27 CCC69333.1 - 6.2e-10 39.7 29.5 0.0065 17.0 0.0 8.6 8 1 0 8 8 7 3 ABC transporter RNA_helicase PF00910.22 CCC69333.1 - 3.4e-09 37.0 8.6 0.65 10.4 0.1 7.9 8 0 0 8 8 6 2 RNA helicase PduV-EutP PF10662.9 CCC69333.1 - 7.9e-09 35.4 2.9 0.11 12.2 0.1 6.0 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.6 CCC69333.1 - 8e-09 36.0 1.2 0.075 13.4 0.0 6.4 6 0 0 6 6 4 2 AAA domain Mg_chelatase PF01078.21 CCC69333.1 - 9.2e-09 35.0 2.6 3.7 6.9 0.0 8.8 9 1 1 10 10 9 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 CCC69333.1 - 2.2e-08 33.9 1.0 0.24 11.0 0.0 5.9 6 0 0 6 6 5 1 AAA domain Zeta_toxin PF06414.12 CCC69333.1 - 3.1e-08 33.1 10.4 0.45 9.8 0.0 7.3 8 0 0 8 8 7 2 Zeta toxin RuvB_N PF05496.12 CCC69333.1 - 3.4e-08 33.4 1.8 1.2 8.8 0.1 6.5 7 0 0 7 7 6 1 Holliday junction DNA helicase RuvB P-loop domain TniB PF05621.11 CCC69333.1 - 1.1e-07 31.4 1.0 1.3 8.4 0.0 6.0 6 0 0 6 6 6 2 Bacterial TniB protein AAA_33 PF13671.6 CCC69333.1 - 1.3e-07 31.9 1.1 0.34 11.1 0.0 5.9 6 0 0 6 6 5 1 AAA domain IstB_IS21 PF01695.17 CCC69333.1 - 1.4e-07 31.4 0.1 3 7.6 0.0 5.8 6 0 0 6 6 6 1 IstB-like ATP binding protein DUF815 PF05673.13 CCC69333.1 - 2.1e-07 30.4 0.3 0.058 12.5 0.1 5.0 5 0 0 5 5 5 1 Protein of unknown function (DUF815) AAA_29 PF13555.6 CCC69333.1 - 2.8e-07 30.2 0.8 1.7 8.5 0.0 6.2 6 0 0 6 6 6 1 P-loop containing region of AAA domain AAA_8 PF12780.7 CCC69333.1 - 3.9e-07 29.7 6.8 0.94 8.8 0.0 6.3 6 0 0 6 6 6 2 P-loop containing dynein motor region D4 Rad17 PF03215.15 CCC69333.1 - 7.4e-07 29.3 2.9 6.1 6.7 0.0 6.4 6 0 0 6 6 6 0 Rad17 P-loop domain NACHT PF05729.12 CCC69333.1 - 1.7e-06 28.0 6.7 1.3 8.9 0.1 5.6 6 0 0 6 6 4 1 NACHT domain VWA PF00092.28 CCC69333.1 - 2.3e-05 24.7 0.4 2.3e-05 24.7 0.4 2.8 2 0 0 2 2 1 1 von Willebrand factor type A domain Roc PF08477.13 CCC69333.1 - 4.3e-05 23.7 9.7 4.9 7.4 0.1 6.9 7 0 0 7 7 6 0 Ras of Complex, Roc, domain of DAPkinase AAA_28 PF13521.6 CCC69333.1 - 4.6e-05 23.7 6.3 7.1 6.8 0.0 5.8 5 0 0 5 5 5 0 AAA domain PhoH PF02562.16 CCC69333.1 - 4.9e-05 22.9 1.9 6.1 6.2 0.0 4.9 5 0 0 5 5 5 0 PhoH-like protein MMR_HSR1 PF01926.23 CCC69333.1 - 5.3e-05 23.3 7.8 7.2 6.7 0.0 6.8 6 0 0 6 6 6 0 50S ribosome-binding GTPase SRP54 PF00448.22 CCC69333.1 - 0.00041 20.0 10.7 0.61 9.7 0.6 5.3 6 0 0 6 6 4 1 SRP54-type protein, GTPase domain ATP-synt_ab PF00006.25 CCC69333.1 - 0.0011 18.7 0.1 4 7.0 0.0 3.9 4 0 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.12 CCC69333.1 - 0.014 15.2 2.0 22 4.9 0.0 5.8 5 1 0 5 5 3 0 Chloramphenicol phosphotransferase-like protein ATP_bind_1 PF03029.17 CCC69333.1 - 0.12 12.1 12.7 6.5 6.4 0.6 5.6 6 0 0 6 6 5 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 CCC69333.1 - 0.95 9.4 12.9 2.2 8.1 0.7 5.1 5 0 0 5 5 5 0 NTPase ATPase PF06745.13 CCC69333.1 - 4.3 6.6 16.1 4.6 6.5 0.1 5.3 6 0 0 6 6 6 0 KaiC tRNA_int_endo PF01974.17 CCC69334.1 - 4.8e-24 84.2 0.5 9.3e-24 83.3 0.5 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain DUF2208 PF09973.9 CCC69334.1 - 0.011 15.4 0.1 0.017 14.7 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) tRNA_int_endo_N PF02778.14 CCC69334.1 - 0.063 13.0 0.6 0.26 11.0 0.0 2.2 3 0 0 3 3 3 0 tRNA intron endonuclease, N-terminal domain LEAP-2 PF07359.11 CCC69335.1 - 0.056 13.3 0.8 0.084 12.7 0.7 1.4 1 1 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) SUIM_assoc PF16619.5 CCC69335.1 - 0.13 12.3 6.9 0.22 11.6 6.9 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MFS_1 PF07690.16 CCC69336.1 - 7.9e-37 127.0 51.8 4.8e-34 117.8 33.5 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.13 CCC69336.1 - 5.8e-11 41.5 8.2 5.8e-11 41.5 8.2 3.1 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 CCC69336.1 - 3e-10 39.6 11.6 3e-10 39.6 11.6 3.4 4 0 0 4 4 4 1 Sugar (and other) transporter DUF4577 PF15145.6 CCC69336.1 - 0.22 11.6 0.8 34 4.5 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4577) CAMSAP_CC1 PF17095.5 CCC69337.1 - 0.066 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Spectrin-binding region of Ca2+-Calmodulin Nuf2 PF03800.14 CCC69338.1 - 2.9e-41 140.9 2.2 2.9e-41 140.9 2.2 2.9 2 1 0 2 2 2 1 Nuf2 family DHR10 PF18595.1 CCC69338.1 - 0.0017 18.4 17.2 0.0017 18.4 17.2 3.2 1 1 0 2 2 2 1 Designed helical repeat protein 10 domain Spc7 PF08317.11 CCC69338.1 - 0.0037 16.2 16.2 0.0037 16.2 16.2 2.5 2 1 1 3 3 3 1 Spc7 kinetochore protein APG6_N PF17675.1 CCC69338.1 - 0.0063 17.1 8.9 0.0063 17.1 8.9 3.4 1 1 2 3 3 3 1 Apg6 coiled-coil region Cyclin_C PF02984.19 CCC69338.1 - 1.2 9.3 9.3 1.1 9.4 0.7 3.3 3 1 1 4 4 4 0 Cyclin, C-terminal domain Mce4_CUP1 PF11887.8 CCC69338.1 - 1.2 8.5 5.7 0.85 9.0 1.5 2.4 2 1 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative HMMR_N PF15905.5 CCC69338.1 - 4.7 6.6 41.1 3 7.2 38.9 1.6 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF592 PF04574.13 CCC69339.1 - 6.9e-70 233.8 2.2 1.2e-69 232.9 2.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) SIR2 PF02146.17 CCC69339.1 - 1.1e-67 227.3 0.0 2e-67 226.5 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CCC69339.1 - 0.0012 18.6 0.0 0.28 10.9 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Inv-AAD PF18785.1 CCC69340.1 - 1.5e-37 128.3 0.0 3.3e-37 127.2 0.0 1.6 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase PseudoU_synth_2 PF00849.22 CCC69340.1 - 2.9e-32 112.0 0.0 6.1e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.23 CCC69340.1 - 2.2e-17 62.8 0.0 4.2e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCC69340.1 - 1.6e-05 24.7 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 MafB19-like deaminase S4 PF01479.25 CCC69340.1 - 0.0014 18.3 0.1 0.0063 16.2 0.0 2.1 2 0 0 2 2 2 1 S4 domain PQQ PF01011.21 CCC69340.1 - 0.0039 17.0 0.1 0.013 15.4 0.1 1.9 1 0 0 1 1 1 1 PQQ enzyme repeat Exo_endo_phos PF03372.23 CCC69341.1 - 5e-05 22.9 0.0 0.00011 21.8 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Inositol_P PF00459.25 CCC69342.1 - 2.9e-57 194.3 0.2 4.4e-56 190.4 0.2 1.9 1 1 0 1 1 1 1 Inositol monophosphatase family DEAD PF00270.29 CCC69343.1 - 1.6e-50 171.3 0.8 1.3e-48 165.0 0.0 2.8 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC69343.1 - 1.1e-22 80.5 0.3 7.1e-22 77.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 CCC69343.1 - 4.7e-19 68.4 5.7 4.7e-19 68.4 5.7 2.7 2 0 0 2 2 2 1 DBP10CT (NUC160) domain ERCC3_RAD25_C PF16203.5 CCC69343.1 - 0.0048 16.1 0.0 0.0048 16.1 0.0 3.2 4 0 0 4 4 4 1 ERCC3/RAD25/XPB C-terminal helicase DUF3449 PF11931.8 CCC69344.1 - 7.8e-64 214.9 0.7 1.8e-63 213.7 0.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) PRP9_N PF16958.5 CCC69344.1 - 4.5e-50 169.6 10.6 4.5e-50 169.6 10.6 2.6 2 0 0 2 2 2 1 Pre-mRNA-splicing factor PRP9 N-terminus SF3A3 PF16837.5 CCC69344.1 - 9.1e-16 58.1 5.7 9.1e-16 58.1 5.7 2.9 2 0 0 2 2 2 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-C2H2_jaz PF12171.8 CCC69344.1 - 1.5e-10 41.1 7.9 2.9e-09 37.0 0.5 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCC69344.1 - 4.7e-05 23.6 3.6 0.04 14.3 0.4 2.9 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 CCC69344.1 - 0.00065 20.0 3.8 0.06 13.7 1.0 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.12 CCC69344.1 - 0.0013 18.4 0.2 0.0036 17.0 0.2 1.7 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_4 PF13894.6 CCC69344.1 - 0.002 18.8 1.3 2.5 9.2 0.1 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger DUF35_N PF12172.8 CCC69344.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF2683 PF10884.8 CCC69344.1 - 0.4 11.0 4.3 0.29 11.4 0.2 2.9 2 2 1 3 3 3 0 Protein of unknown function (DUF2683) Actin PF00022.19 CCC69345.1 - 1.2e-111 373.3 0.0 3.8e-111 371.6 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 CCC69345.1 - 0.0049 15.7 0.0 0.03 13.1 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Pkinase PF00069.25 CCC69346.1 - 1.5e-50 172.0 0.0 3e-50 171.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69346.1 - 1.2e-25 90.3 0.0 2.5e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC69346.1 - 2.8e-06 26.9 0.0 0.018 14.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CCC69346.1 - 0.00022 21.2 0.0 0.06 13.3 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 CCC69346.1 - 0.0023 17.6 0.1 0.45 10.1 0.0 2.7 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 CCC69346.1 - 0.01 15.4 3.5 0.011 15.4 0.5 2.4 2 1 1 3 3 3 0 RIO1 family CRT10 PF08728.10 CCC69347.1 - 4.4e-145 484.7 0.8 3e-144 481.9 0.8 1.9 1 1 0 1 1 1 1 CRT10 Adap_comp_sub PF00928.21 CCC69348.1 - 3.5e-77 259.3 0.6 5.1e-77 258.8 0.6 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pribosyl_synth PF14572.6 CCC69349.1 - 4.8e-42 144.1 1.2 1.3e-41 142.7 0.8 1.9 2 1 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.6 CCC69349.1 - 3.2e-33 114.1 0.0 9.3e-33 112.6 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 CCC69349.1 - 3.8e-12 46.0 1.3 1.1e-10 41.2 1.2 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCC69349.1 - 0.088 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase MFS_1 PF07690.16 CCC69350.1 - 1.8e-43 148.9 24.9 2.3e-37 128.8 14.2 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.6 CCC69350.1 - 0.12 12.4 3.0 0.27 11.3 3.0 1.6 1 0 0 1 1 1 0 Glycine zipper NAD_Gly3P_dh_N PF01210.23 CCC69352.1 - 1.6e-51 174.3 0.3 2.9e-51 173.6 0.3 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CCC69352.1 - 1.4e-40 138.8 0.1 3.2e-40 137.7 0.1 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CCC69352.1 - 0.0028 18.2 0.2 0.091 13.4 0.2 2.5 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 CCC69352.1 - 0.04 13.8 0.1 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 CCC69352.1 - 0.095 13.1 0.1 0.49 10.9 0.1 2.1 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Arginosuc_synth PF00764.19 CCC69353.1 - 4.2e-165 549.7 0.0 4.8e-165 549.5 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 CCC69353.1 - 9.5e-05 22.0 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.16 CCC69353.1 - 0.0025 16.7 0.0 0.0036 16.1 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 CCC69353.1 - 0.019 14.6 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Asparagine synthase Peptidase_M49 PF03571.15 CCC69354.1 - 2.7e-230 765.5 0.0 3.6e-230 765.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M49 Prenyltransf PF01255.19 CCC69354.1 - 0.064 12.8 0.4 0.12 11.9 0.4 1.3 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase His_Phos_1 PF00300.22 CCC69355.1 - 2e-33 115.7 0.0 1.2e-15 57.7 0.0 3.0 2 1 1 3 3 3 3 Histidine phosphatase superfamily (branch 1) Tir_receptor_M PF03549.14 CCC69355.1 - 0.14 12.5 0.0 0.44 10.9 0.0 1.9 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) intimin-binding domain zf-C2H2 PF00096.26 CCC69356.1 - 0.0023 18.3 12.8 0.099 13.1 0.2 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type YL1 PF05764.13 CCC69356.1 - 0.43 10.6 6.6 1.1 9.3 6.6 1.8 1 0 0 1 1 1 0 YL1 nuclear protein zf-C2H2_4 PF13894.6 CCC69356.1 - 2.9 9.0 15.3 2.3 9.3 0.7 4.1 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCC69356.1 - 7.3 6.7 9.2 0.37 10.9 0.6 2.9 3 0 0 3 3 3 0 C2H2-type zinc finger Phos_pyr_kin PF08543.12 CCC69357.1 - 2.6e-77 259.5 0.4 3.3e-77 259.2 0.4 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.16 CCC69357.1 - 2.6e-60 203.8 0.6 3.5e-60 203.4 0.6 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Carb_kinase PF01256.17 CCC69357.1 - 0.017 14.6 0.3 0.046 13.2 0.3 1.8 1 1 0 1 1 1 0 Carbohydrate kinase Oxysterol_BP PF01237.18 CCC69358.1 - 7.8e-129 429.7 0.0 1.5e-128 428.8 0.0 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.6 CCC69358.1 - 9.2e-12 45.0 0.0 0.00014 22.1 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCC69358.1 - 3.2e-10 40.3 0.1 0.00026 21.5 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (many copies) PH PF00169.29 CCC69358.1 - 3.5e-10 40.3 0.2 1e-09 38.8 0.2 1.9 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.7 CCC69358.1 - 6.6e-10 39.4 0.1 7e-05 23.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 CCC69358.1 - 3.2e-09 36.3 0.0 0.011 16.2 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat PH_8 PF15409.6 CCC69358.1 - 3.5e-08 33.6 1.2 2.7e-07 30.7 0.1 2.9 3 0 0 3 3 3 1 Pleckstrin homology domain Ank PF00023.30 CCC69358.1 - 8.2e-06 26.0 0.0 0.044 14.2 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat PH_11 PF15413.6 CCC69358.1 - 0.0097 16.3 0.8 0.0097 16.3 0.8 4.4 4 1 0 4 4 4 1 Pleckstrin homology domain DUF4349 PF14257.6 CCC69358.1 - 0.18 11.2 1.6 0.48 9.8 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Pkinase PF00069.25 CCC69359.1 - 6.4e-74 248.6 0.1 1.2e-73 247.8 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69359.1 - 1.9e-52 178.1 0.0 3.2e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC69359.1 - 0.00081 18.8 0.4 0.0084 15.4 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 CCC69359.1 - 0.1 11.4 0.1 0.19 10.5 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase DUF3237 PF11578.8 CCC69359.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3237) Actin PF00022.19 CCC69360.1 - 7.9e-152 505.6 0.0 2.3e-151 504.0 0.0 1.6 1 1 0 1 1 1 1 Actin Ras PF00071.22 CCC69361.1 - 2.1e-64 216.0 0.5 2.4e-64 215.8 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC69361.1 - 7.9e-36 122.9 0.2 1.2e-35 122.3 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC69361.1 - 5e-17 61.9 0.2 6.7e-17 61.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCC69361.1 - 7.3e-06 25.6 0.3 1.7e-05 24.4 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 CCC69361.1 - 1e-05 25.0 0.2 1.2e-05 24.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCC69361.1 - 0.00026 21.0 0.1 0.00049 20.2 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCC69361.1 - 0.0018 18.2 0.7 0.11 12.4 0.1 2.2 1 1 1 2 2 2 1 RsgA GTPase SRPRB PF09439.10 CCC69361.1 - 0.0024 17.3 0.1 0.0034 16.8 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_5 PF07728.14 CCC69361.1 - 0.064 13.3 0.1 0.12 12.4 0.0 1.8 1 1 1 2 2 2 0 AAA domain (dynein-related subfamily) Septin PF00735.18 CCC69361.1 - 0.07 12.4 0.2 0.13 11.5 0.0 1.4 2 0 0 2 2 2 0 Septin AAA_29 PF13555.6 CCC69361.1 - 0.093 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 CCC69361.1 - 0.099 13.2 0.3 0.22 12.1 0.3 1.8 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 CCC69361.1 - 0.1 12.2 0.2 0.5 9.9 0.2 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 CCC69361.1 - 0.1 13.0 0.0 0.14 12.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 CCC69361.1 - 0.11 12.9 0.1 0.74 10.2 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CCC69361.1 - 0.14 11.7 0.5 0.26 10.8 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region RNA_pol PF00940.19 CCC69362.1 - 9.6e-179 594.5 0.0 1.6e-178 593.8 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 CCC69362.1 - 1.1e-99 334.0 0.1 2.1e-99 333.1 0.1 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Spore_III_AB PF09548.10 CCC69362.1 - 0.45 10.6 4.0 16 5.6 0.5 2.9 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Mob1_phocein PF03637.17 CCC69363.1 - 1.9e-65 220.0 1.3 3.1e-65 219.3 1.3 1.3 1 0 0 1 1 1 1 Mob1/phocein family Ribosomal_L22e PF01776.17 CCC69364.1 - 5.1e-39 133.0 0.3 6.4e-39 132.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF726 PF05277.12 CCC69365.1 - 8.3e-141 468.9 1.9 1.3e-140 468.2 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) tRNA_synthFbeta PF17759.1 CCC69366.1 - 5.7e-42 143.6 0.0 9.4e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 CCC69366.1 - 4.7e-30 103.6 0.8 3e-29 101.1 0.4 2.2 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 CCC69366.1 - 1.1e-27 96.8 0.0 1.9e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 CCC69366.1 - 3.1e-16 59.4 0.0 1.3e-14 54.2 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain Pkinase PF00069.25 CCC69367.1 - 8.4e-60 202.4 0.0 3.1e-35 121.8 0.1 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69367.1 - 3.2e-24 85.6 0.0 7e-19 68.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.24 CCC69367.1 - 6.2e-07 29.6 0.0 1.3e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 CCC69367.1 - 0.0023 17.3 0.0 0.26 10.5 0.0 2.4 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 CCC69367.1 - 0.0079 16.1 0.5 1.1 9.1 1.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 CCC69367.1 - 0.043 13.2 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_1 PF00170.21 CCC69368.1 - 0.00043 20.3 8.5 0.001 19.1 8.5 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CCC69368.1 - 0.0066 16.5 7.4 0.0066 16.5 7.4 1.9 1 1 0 1 1 1 1 Basic region leucine zipper Qn_am_d_aIV PF09100.10 CCC69368.1 - 0.043 13.6 0.1 0.077 12.8 0.1 1.5 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV SARA PF11409.8 CCC69368.1 - 0.062 13.5 1.5 12 6.2 0.0 2.8 2 0 0 2 2 2 0 Smad anchor for receptor activation (SARA) HTH_25 PF13413.6 CCC69368.1 - 0.077 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain Aminotran_5 PF00266.19 CCC69369.1 - 9.7e-28 97.2 0.0 1.2e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 CCC69369.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II SHMT PF00464.19 CCC69370.1 - 1.4e-206 685.8 0.0 1.6e-206 685.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 CCC69370.1 - 0.00016 21.1 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase DUF4559 PF15112.6 CCC69370.1 - 0.25 11.0 1.2 0.41 10.3 1.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4559) Pkinase PF00069.25 CCC69371.1 - 3.7e-24 85.5 0.0 4.3e-23 82.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69371.1 - 1.2e-08 34.6 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC69371.1 - 0.014 14.2 0.1 0.02 13.7 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CCC69371.1 - 0.04 13.8 0.1 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 CCC69371.1 - 0.053 12.9 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 CCC69371.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL ABC_tran PF00005.27 CCC69372.1 - 7.3e-18 65.4 0.0 1.4e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 CCC69372.1 - 6.1e-09 36.1 4.0 0.00091 19.1 0.1 2.5 3 0 0 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCC69372.1 - 1.5e-05 24.6 0.0 0.083 12.3 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCC69372.1 - 0.0011 18.6 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 CCC69372.1 - 0.006 17.1 0.0 0.0098 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 CCC69372.1 - 0.018 14.8 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 CCC69372.1 - 0.026 14.4 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 CCC69372.1 - 0.027 14.5 0.0 0.041 13.9 0.0 1.3 1 0 0 1 1 1 0 Dynamin family AAA_22 PF13401.6 CCC69372.1 - 0.038 14.2 0.2 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 CCC69372.1 - 0.045 14.2 0.1 6.4 7.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.18 CCC69372.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 CCC69372.1 - 0.071 13.5 0.2 0.12 12.7 0.2 1.5 1 1 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.23 CCC69372.1 - 0.09 12.9 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.6 CCC69372.1 - 0.093 12.9 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.8 CCC69372.1 - 0.1 10.1 0.1 0.13 9.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Zeta_toxin PF06414.12 CCC69372.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_27 PF13514.6 CCC69372.1 - 0.14 11.7 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 CCC69372.1 - 0.17 12.1 0.2 0.33 11.2 0.2 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CCC69372.1 - 0.18 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain RabGAP-TBC PF00566.18 CCC69373.1 - 2e-14 53.8 10.3 2e-14 53.8 10.3 2.4 2 1 0 2 2 2 1 Rab-GTPase-TBC domain STE2 PF02116.15 CCC69374.1 - 2.7e-90 302.5 25.8 3.2e-90 302.2 25.8 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF2976 PF11190.8 CCC69374.1 - 0.069 13.0 5.6 0.096 12.5 1.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF412 PF04217.13 CCC69374.1 - 1.2 9.0 5.2 4.5 7.2 0.5 2.7 2 0 0 2 2 2 0 Protein of unknown function, DUF412 PGAP1 PF07819.13 CCC69375.1 - 1.5e-92 309.5 0.0 3.2e-92 308.4 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein CdiI_N PF18228.1 CCC69375.1 - 0.064 13.1 0.3 0.19 11.6 0.3 1.8 1 0 0 1 1 1 0 CdiI N-terminal domain Abhydrolase_6 PF12697.7 CCC69375.1 - 0.068 13.8 0.0 0.12 13.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Palm_thioest PF02089.15 CCC69375.1 - 0.081 12.8 0.0 0.25 11.2 0.0 1.9 1 0 0 1 1 1 0 Palmitoyl protein thioesterase EPL1 PF10513.9 CCC69376.1 - 3.9e-23 82.6 4.3 3.9e-23 82.6 4.3 3.7 3 1 0 3 3 3 1 Enhancer of polycomb-like ArlS_N PF18719.1 CCC69376.1 - 0.0067 16.6 0.2 0.0067 16.6 0.2 3.8 4 0 0 4 4 4 1 ArlS sensor domain DUF3835 PF12927.7 CCC69377.1 - 1.6e-19 70.5 0.4 1.6e-19 70.5 0.4 6.8 6 1 0 6 6 6 3 Domain of unknown function (DUF3835) Prefoldin PF02996.17 CCC69377.1 - 1.5e-14 53.9 3.7 1.5e-14 53.9 3.7 3.4 3 0 0 3 3 3 1 Prefoldin subunit GCR1_C PF12550.8 CCC69378.1 - 3.1e-09 37.0 0.5 4.5e-08 33.3 0.3 2.4 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes Noelin-1 PF12308.8 CCC69378.1 - 0.096 12.7 0.4 0.24 11.4 0.4 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein Strep_SA_rep PF06696.11 CCC69381.1 - 3.1 7.9 7.0 6.9 6.8 7.0 1.6 1 0 0 1 1 1 0 Streptococcal surface antigen repeat GATA PF00320.27 CCC69382.1 - 2.5e-15 55.8 3.4 5.5e-15 54.7 3.4 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.10 CCC69382.1 - 1.1e-08 34.7 1.7 6.3e-08 32.3 1.6 2.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.12 CCC69382.1 - 0.011 15.2 1.4 0.031 13.8 1.3 1.8 1 1 0 1 1 1 0 TFIIB zinc-binding DUF4284 PF14112.6 CCC69382.1 - 0.014 16.3 4.5 0.23 12.4 0.1 2.6 2 0 0 2 2 2 0 Immunity protein 22 OrfB_Zn_ribbon PF07282.11 CCC69382.1 - 0.11 12.4 0.6 0.24 11.3 0.6 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain LSM PF01423.22 CCC69383.1 - 9.9e-19 66.8 0.2 1.1e-18 66.7 0.2 1.0 1 0 0 1 1 1 1 LSM domain Acetyltransf_1 PF00583.25 CCC69384.1 - 5.8e-11 42.7 0.0 7.4e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCC69384.1 - 1.9e-07 31.4 0.0 2.8e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CCC69384.1 - 7.4e-06 25.9 0.0 1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DnaJ PF00226.31 CCC69385.1 - 2.5e-25 88.4 5.2 5.7e-25 87.2 5.2 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 CCC69385.1 - 1e-23 84.1 0.1 1.7e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 CCC69385.1 - 1.4e-12 47.8 17.8 2.8e-12 46.8 17.8 1.6 1 0 0 1 1 1 1 DnaJ central domain Cytochrome_C7 PF14522.6 CCC69385.1 - 6.1e-05 22.9 10.5 0.03 14.3 1.7 2.8 2 0 0 2 2 2 2 Cytochrome c7 and related cytochrome c Cytochrom_c3_2 PF14537.6 CCC69385.1 - 0.0077 16.7 15.5 0.16 12.4 15.5 2.6 1 1 1 2 2 2 2 Cytochrome c3 HypA PF01155.19 CCC69385.1 - 0.025 14.6 8.4 0.36 10.9 0.8 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 CCC69385.1 - 0.44 10.5 16.8 0.46 10.5 5.1 3.1 2 1 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein Zn_Tnp_IS1595 PF12760.7 CCC69385.1 - 0.78 9.8 3.1 1.9 8.5 3.1 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc-ribbons_6 PF07191.12 CCC69385.1 - 1.1 9.2 8.0 2.2 8.3 8.0 1.4 1 0 0 1 1 1 0 zinc-ribbons HSP9_HSP12 PF04119.12 CCC69386.1 - 1.4e-27 95.8 8.1 2.5e-27 95.0 1.8 2.3 2 1 0 2 2 2 2 Heat shock protein 9/12 YtxH PF12732.7 CCC69386.1 - 0.43 11.1 8.6 1.5 9.4 0.9 2.5 1 1 1 2 2 2 0 YtxH-like protein FAM25 PF15825.5 CCC69386.1 - 2 8.8 6.6 0.98 9.8 1.5 2.5 1 1 2 3 3 3 0 FAM25 family Claudin_3 PF06653.11 CCC69388.1 - 0.0023 17.9 3.1 0.0028 17.6 3.1 1.1 1 0 0 1 1 1 1 Tight junction protein, Claudin-like DUF2206 PF09971.9 CCC69388.1 - 0.003 16.4 4.1 0.0035 16.2 4.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2206) Imm17 PF15562.6 CCC69388.1 - 0.014 15.2 0.2 0.014 15.2 0.2 1.9 2 0 0 2 2 2 0 Immunity protein 17 WD40 PF00400.32 CCC69389.1 - 1.3e-36 123.9 18.8 2.5e-07 31.3 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat CDC4_D PF16856.5 CCC69389.1 - 2.7e-18 65.6 7.5 5.7e-18 64.5 7.5 1.6 1 0 0 1 1 1 1 Cell division control protein 4 dimerisation domain F-box-like PF12937.7 CCC69389.1 - 1.1e-12 47.6 2.1 1.7e-12 47.0 0.6 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 CCC69389.1 - 9.2e-09 35.0 1.0 2.7e-08 33.5 0.4 2.1 2 0 0 2 2 2 1 F-box domain ANAPC4_WD40 PF12894.7 CCC69389.1 - 6.2e-05 23.2 0.1 0.85 10.0 0.0 4.6 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PRANC PF09372.10 CCC69389.1 - 0.00076 19.8 1.9 0.00076 19.8 1.9 2.2 2 0 0 2 2 2 1 PRANC domain RseA_C PF03873.13 CCC69389.1 - 0.011 16.0 0.0 0.05 13.9 0.0 2.1 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain PQQ_2 PF13360.6 CCC69389.1 - 0.025 14.2 0.2 0.14 11.8 0.0 2.3 3 0 0 3 3 3 0 PQQ-like domain SMC_N PF02463.19 CCC69390.1 - 7.3e-68 228.3 0.4 5.1e-67 225.5 0.4 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCC69390.1 - 1.5e-25 89.8 0.0 4.6e-25 88.2 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 CCC69390.1 - 3.5e-10 40.7 38.6 3.5e-10 40.7 38.6 7.0 2 2 1 4 4 4 1 AAA domain AAA_21 PF13304.6 CCC69390.1 - 1.1e-08 35.3 24.4 9.9e-06 25.6 0.2 5.1 3 2 2 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCC69390.1 - 1.8e-08 34.0 0.1 3.8e-08 33.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CCC69390.1 - 1.9e-07 31.2 27.5 1.9e-07 31.2 27.5 4.7 2 2 2 4 4 4 1 AAA ATPase domain AAA_27 PF13514.6 CCC69390.1 - 0.094 12.3 0.1 0.094 12.3 0.1 5.4 6 0 0 6 6 6 0 AAA domain ABC_tran PF00005.27 CCC69390.1 - 0.12 12.9 0.0 0.12 12.9 0.0 6.6 4 3 0 4 4 4 0 ABC transporter BLM10_mid PF16507.5 CCC69391.1 - 1.1e-166 555.5 13.1 2.9e-166 554.2 13.1 1.8 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region BLM10_N PF16547.5 CCC69391.1 - 3.4e-29 100.9 0.6 8.4e-29 99.7 0.6 1.7 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, N-terminal DUF3437 PF11919.8 CCC69391.1 - 3.2e-26 91.1 0.0 3.3e-25 87.8 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.22 CCC69391.1 - 0.088 13.1 0.1 9 6.9 0.0 3.7 3 0 0 3 3 3 0 HEAT repeat Ras PF00071.22 CCC69392.1 - 1.4e-63 213.4 0.4 1.6e-63 213.1 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC69392.1 - 2.3e-37 127.8 0.3 3.4e-37 127.3 0.3 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC69392.1 - 3.7e-19 68.8 0.1 4.5e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 CCC69392.1 - 1.5e-07 31.0 0.2 1.9e-07 30.7 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CCC69392.1 - 7.7e-07 28.7 0.1 8.6e-07 28.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCC69392.1 - 2.2e-06 27.7 0.1 3.5e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCC69392.1 - 4.2e-06 26.8 0.2 0.084 12.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 CCC69392.1 - 2e-05 24.2 0.3 0.00036 20.1 0.1 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 CCC69392.1 - 0.0096 15.5 0.1 0.12 11.8 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 CCC69392.1 - 0.024 14.2 0.0 0.056 12.9 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 CCC69392.1 - 0.031 14.0 0.1 0.1 12.3 0.1 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain MCM PF00493.23 CCC69392.1 - 0.037 13.1 0.1 0.093 11.8 0.0 1.7 2 1 0 2 2 2 0 MCM P-loop domain AAA_22 PF13401.6 CCC69392.1 - 0.05 13.9 0.1 0.13 12.5 0.0 1.9 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.9 CCC69392.1 - 0.063 13.0 0.0 0.55 10.0 0.0 2.0 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.13 CCC69392.1 - 0.11 11.7 0.0 0.24 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_16 PF13191.6 CCC69392.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain VTC PF09359.10 CCC69393.1 - 1.7e-95 319.5 0.1 1.7e-95 319.5 0.1 2.7 3 0 0 3 3 3 1 VTC domain SPX PF03105.19 CCC69393.1 - 1.1e-11 45.3 26.5 0.00029 20.9 0.2 4.3 2 1 2 4 4 4 3 SPX domain DUF202 PF02656.15 CCC69393.1 - 1.3e-11 44.7 1.7 1.7e-11 44.4 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Bax1-I PF01027.20 CCC69393.1 - 0.075 12.9 0.5 0.12 12.2 0.5 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2975 PF11188.8 CCC69393.1 - 0.077 12.9 0.5 0.15 12.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) NCE101 PF11654.8 CCC69393.1 - 0.081 12.6 0.0 0.22 11.3 0.0 1.7 1 0 0 1 1 1 0 Non-classical export protein 1 DUF4149 PF13664.6 CCC69393.1 - 0.15 12.4 1.2 0.61 10.4 1.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) GNAT_acetyltran PF12746.7 CCC69393.1 - 0.4 10.2 3.0 1.1 8.8 3.0 1.7 1 0 0 1 1 1 0 GNAT acetyltransferase MutS_V PF00488.21 CCC69394.1 - 1e-45 156.1 0.1 2.6e-45 154.8 0.1 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 CCC69394.1 - 6.2e-28 98.3 6.6 1.3e-27 97.3 4.1 2.4 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.17 CCC69394.1 - 3.8e-11 43.4 1.0 8.9e-11 42.2 0.1 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 CCC69394.1 - 1.6e-09 38.0 0.4 1.6e-09 38.0 0.4 2.3 2 0 0 2 2 2 1 MutS family domain IV AAA_14 PF13173.6 CCC69394.1 - 0.23 11.5 0.1 0.23 11.5 0.1 3.4 3 1 0 3 3 3 0 AAA domain NFACT-C PF11923.8 CCC69395.1 - 2.3e-34 117.5 1.0 2.3e-34 117.5 1.0 3.6 3 1 1 4 4 4 1 NFACT protein C-terminal domain FbpA PF05833.11 CCC69395.1 - 2.3e-22 79.4 0.2 2.3e-22 79.4 0.2 3.8 2 1 1 3 3 3 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 CCC69395.1 - 3.4e-18 66.3 1.3 6.3e-18 65.4 0.2 2.2 2 0 0 2 2 2 1 NFACT protein RNA binding domain 2-Hacid_dh_C PF02826.19 CCC69396.1 - 6.4e-29 100.6 0.0 1.4e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCC69396.1 - 6e-07 29.2 0.0 2.1e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 CCC69396.1 - 0.0066 16.6 0.0 0.011 15.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 CCC69396.1 - 0.048 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-C2H2 PF00096.26 CCC69397.1 - 3.2e-09 36.7 20.9 2.1e-05 24.7 2.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC69397.1 - 3.2e-07 30.5 17.2 1.6e-05 25.1 5.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC69397.1 - 2.6e-06 27.8 18.1 0.00057 20.5 1.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCC69397.1 - 3.2e-06 27.3 10.6 0.0084 16.5 1.2 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCC69397.1 - 1e-05 25.7 12.5 0.0065 16.7 6.0 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCC69397.1 - 8.4e-05 22.5 0.9 8.4e-05 22.5 0.9 2.7 2 1 0 2 2 2 1 C2H2-type zinc finger zf-BED PF02892.15 CCC69397.1 - 0.072 13.1 7.1 1.5 8.9 1.9 2.5 2 0 0 2 2 2 0 BED zinc finger DZR PF12773.7 CCC69397.1 - 0.095 12.7 0.3 0.19 11.7 0.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon zf-Di19 PF05605.12 CCC69397.1 - 0.48 10.7 6.5 1.3 9.3 6.6 1.7 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CCC69397.1 - 0.87 10.0 9.7 1.4 9.3 0.7 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Mnd1 PF03962.15 CCC69398.1 - 1.5e-12 47.6 0.5 1.5e-12 47.6 0.5 2.7 3 0 0 3 3 3 1 Mnd1 HTH domain LZ3wCH PF18517.1 CCC69398.1 - 2.5e-05 24.3 1.8 2.5e-05 24.3 1.8 2.7 3 0 0 3 3 3 1 Leucine zipper with capping helix domain ArfGap PF01412.18 CCC69399.1 - 2e-29 102.0 0.0 3.6e-29 101.2 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.31 CCC69399.1 - 0.00019 21.3 0.0 0.00042 20.1 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain HypA PF01155.19 CCC69399.1 - 0.18 11.8 0.2 0.33 11.0 0.2 1.4 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Effector_1 PF04518.12 CCC69399.1 - 0.18 10.9 7.7 0.37 9.9 7.7 1.4 1 0 0 1 1 1 0 Effector from type III secretion system DUF3543 PF12063.8 CCC69400.1 - 6.3e-88 294.4 4.3 1.1e-87 293.6 4.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.25 CCC69400.1 - 2.1e-54 184.7 0.1 3.4e-53 180.7 0.1 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69400.1 - 1.3e-41 142.6 0.0 2.3e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Oxidored_FMN PF00724.20 CCC69401.1 - 2.2e-119 398.7 0.0 2.6e-119 398.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.25 CCC69402.1 - 6.7e-57 192.9 0.0 1.2e-56 192.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69402.1 - 7.5e-29 100.8 0.0 1.6e-28 99.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC69402.1 - 4.6e-07 29.4 0.0 9e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CCC69402.1 - 0.00035 19.8 0.3 0.0015 17.7 0.0 2.2 2 1 1 3 3 3 1 Seadornavirus VP7 APH PF01636.23 CCC69402.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 CCC69402.1 - 0.021 14.5 0.2 4.3 6.9 0.0 2.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PUF PF00806.19 CCC69403.1 - 1.1e-56 185.4 29.1 4.6e-08 32.3 1.5 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF3361 PF11841.8 CCC69403.1 - 0.017 15.0 3.3 0.51 10.3 0.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3361) Foie-gras_1 PF11817.8 CCC69403.1 - 0.61 9.6 3.8 1.3 8.6 3.8 1.5 1 0 0 1 1 1 0 Foie gras liver health family 1 UPF0262 PF06793.12 CCC69404.1 - 0.0083 16.2 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0262) CNH PF00780.22 CCC69404.1 - 0.014 15.0 0.0 0.49 10.0 0.1 2.2 1 1 1 2 2 2 0 CNH domain Bud13 PF09736.9 CCC69406.1 - 1.1e-22 81.0 14.9 9.8e-22 77.9 5.6 3.1 2 2 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex XRN_N PF03159.18 CCC69407.1 - 1.2e-93 313.0 0.1 1.2e-93 313.0 0.1 1.8 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 CCC69407.1 - 8.3e-86 288.7 5.5 8.3e-86 288.7 5.5 2.2 2 0 0 2 2 2 1 Xrn1 helical domain XRN1_D1 PF18332.1 CCC69407.1 - 2.6e-66 223.1 0.1 2.6e-66 223.1 0.1 2.5 3 0 0 3 3 3 1 Exoribonuclease Xrn1 D1 domain XRN1_D2_D3 PF18334.1 CCC69407.1 - 1.1e-29 102.5 1.5 1.7e-29 101.9 0.0 2.2 2 0 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain Xrn1_D3 PF18194.1 CCC69407.1 - 3.8e-22 78.2 0.8 1.2e-21 76.6 0.8 1.9 1 0 0 1 1 1 1 Exoribonuclease 1 Domain-3 SH3_12 PF18129.1 CCC69407.1 - 6e-19 67.9 0.3 1.1e-18 67.1 0.3 1.4 1 0 0 1 1 1 1 Xrn1 SH3-like domain Caudo_TAP PF02413.17 CCC69407.1 - 4.1 7.5 7.3 9.5 6.4 0.1 3.6 3 0 0 3 3 3 0 Caudovirales tail fibre assembly protein, lambda gpK Nucleoporin_FG PF13634.6 CCC69408.1 - 9.5e-30 103.3 146.2 8.1e-13 49.0 32.3 5.8 2 1 4 6 6 6 5 Nucleoporin FG repeat region ATP-synt_G PF04718.15 CCC69409.1 - 1.5e-30 106.0 0.0 1.9e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit MCM PF00493.23 CCC69410.1 - 1.2e-100 335.2 0.0 1.9e-100 334.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCC69410.1 - 5.6e-37 126.4 0.4 1.5e-36 125.0 0.5 1.7 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 CCC69410.1 - 8.2e-29 99.9 1.9 1.9e-28 98.7 1.9 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCC69410.1 - 1.3e-16 61.1 8.0 1.3e-16 61.0 5.3 2.4 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.14 CCC69410.1 - 2.7e-06 27.4 0.0 6.8e-05 22.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCC69410.1 - 1.6e-05 24.4 0.0 0.00061 19.2 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CCC69410.1 - 0.0011 18.8 0.0 0.0099 15.7 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCC69410.1 - 0.0022 18.4 0.6 1.2 9.4 0.1 3.4 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 CCC69410.1 - 0.088 12.5 0.1 3.5 7.3 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain Mnd1 PF03962.15 CCC69410.1 - 0.51 10.7 1.9 4 7.8 0.1 2.8 2 0 0 2 2 2 0 Mnd1 HTH domain DUF334 PF03904.13 CCC69410.1 - 4.3 6.8 9.8 3.1 7.3 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF334) CAF1A PF12253.8 CCC69411.1 - 1.4e-20 73.2 11.0 1.4e-20 73.2 11.0 4.3 4 1 0 4 4 4 1 Chromatin assembly factor 1 subunit A Wax2_C PF12076.8 CCC69412.1 - 0.066 12.9 0.8 0.18 11.6 0.2 1.9 1 1 1 2 2 2 0 WAX2 C-terminal domain zf-C2H2 PF00096.26 CCC69413.1 - 7.1e-09 35.6 10.0 0.00041 20.6 1.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC69413.1 - 3.6e-06 27.3 9.6 0.0091 16.8 1.7 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCC69413.1 - 6.7e-05 23.1 0.7 6.7e-05 23.1 0.7 3.8 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.7 CCC69413.1 - 0.00038 20.8 8.7 0.013 15.9 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCC69413.1 - 0.0046 17.2 6.9 0.56 10.6 0.0 2.7 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding RNA_pol_Rpb2_6 PF00562.28 CCC69414.1 - 1.1e-113 380.3 0.0 2.6e-113 379.0 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CCC69414.1 - 7.3e-47 159.5 0.1 1e-46 159.0 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CCC69414.1 - 6.9e-38 130.2 0.0 2.7e-37 128.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 CCC69414.1 - 6.5e-28 96.7 0.0 1.7e-27 95.4 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.12 CCC69414.1 - 1.8e-23 82.3 0.0 3.8e-23 81.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.20 CCC69414.1 - 2.7e-16 59.7 0.0 1.1e-14 54.6 0.0 2.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 E1-E2_ATPase PF00122.20 CCC69415.1 - 1.9e-49 167.6 0.0 1.9e-49 167.6 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 CCC69415.1 - 2.6e-47 160.9 2.3 2.6e-47 160.9 2.3 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 CCC69415.1 - 1e-21 78.2 0.0 4.6e-21 76.1 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCC69415.1 - 3.2e-21 75.2 0.2 9.2e-21 73.7 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 CCC69415.1 - 1.4e-15 56.8 0.0 5.4e-15 54.8 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 CCC69415.1 - 5.1e-05 23.1 0.3 0.0026 17.6 0.5 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase SPC12 PF06645.13 CCC69415.1 - 0.34 11.0 1.3 2.1 8.5 1.3 2.4 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Sua5_yciO_yrdC PF01300.18 CCC69416.1 - 2.1e-46 157.7 0.1 3.7e-46 156.9 0.1 1.4 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.13 CCC69416.1 - 1.4e-27 96.9 0.0 2.2e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding DUF928 PF06051.12 CCC69416.1 - 0.083 12.7 0.4 0.19 11.6 0.4 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) COX7C PF02935.16 CCC69417.1 - 6.1 7.2 6.2 0.5 10.7 0.8 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Zn_clus PF00172.18 CCC69418.1 - 0.0033 17.5 3.7 0.0033 17.5 3.7 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4606 PF15379.6 CCC69418.1 - 7.1 6.9 6.8 4.5 7.6 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4606) DCP1 PF06058.13 CCC69419.1 - 4.5e-25 87.9 0.6 6.6e-13 48.6 0.2 2.4 1 1 0 2 2 2 2 Dcp1-like decapping family Kelch_4 PF13418.6 CCC69419.1 - 0.11 12.5 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Galactose oxidase, central domain Spt20 PF12090.8 CCC69420.1 - 7.1e-68 228.7 6.7 7.1e-68 228.7 6.7 4.9 3 2 1 4 4 4 1 Spt20 family KH_6 PF15985.5 CCC69421.1 - 2e-13 50.5 0.0 3.2e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 CCC69421.1 - 2.5e-12 46.5 0.1 4.5e-12 45.7 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain Hist_deacetyl PF00850.19 CCC69422.1 - 2.9e-84 283.1 0.1 5e-84 282.4 0.0 1.4 2 0 0 2 2 2 1 Histone deacetylase domain DMRL_synthase PF00885.19 CCC69423.1 - 8.1e-53 178.0 0.2 9.5e-53 177.8 0.2 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RRM_1 PF00076.22 CCC69424.1 - 0.00021 21.0 2.1 0.00033 20.4 0.5 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_2 PF07719.17 CCC69425.1 - 7.8e-25 85.0 36.9 0.0094 16.0 0.0 13.3 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_1 PF00515.28 CCC69425.1 - 7.5e-22 76.2 47.0 0.00055 19.6 0.0 13.0 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_12 PF13424.6 CCC69425.1 - 1.2e-20 73.5 19.5 0.015 15.6 0.4 10.1 8 2 1 9 9 9 7 Tetratricopeptide repeat TPR_16 PF13432.6 CCC69425.1 - 1.5e-17 63.9 0.1 0.0018 18.9 0.2 7.3 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCC69425.1 - 1.8e-15 56.3 11.6 0.0026 18.5 0.1 12.2 10 3 4 14 14 13 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCC69425.1 - 9.2e-15 54.9 22.9 1.9e-05 25.1 0.0 8.9 7 3 3 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 CCC69425.1 - 5.7e-13 48.0 36.3 0.0047 17.0 0.1 12.8 14 0 0 14 14 13 4 Tetratricopeptide repeat TPR_6 PF13174.6 CCC69425.1 - 6.4e-09 35.9 30.6 0.5 11.1 0.0 12.9 15 0 0 15 15 13 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCC69425.1 - 2.9e-08 33.3 11.9 0.61 9.8 0.0 7.0 7 0 0 7 7 7 3 TPR repeat ANAPC3 PF12895.7 CCC69425.1 - 3.7e-07 30.3 24.9 0.0014 18.8 0.6 7.3 4 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 CCC69425.1 - 0.00033 20.5 20.9 0.55 10.4 0.1 9.1 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCC69425.1 - 0.0015 18.8 15.4 4.1 8.0 0.0 9.2 11 0 0 11 11 10 1 Tetratricopeptide repeat B-block_TFIIIC PF04182.12 CCC69425.1 - 0.051 13.7 0.2 0.19 11.9 0.2 2.0 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC YfiO PF13525.6 CCC69425.1 - 0.083 12.6 13.4 0.18 11.5 0.0 5.8 4 2 2 6 6 6 0 Outer membrane lipoprotein TPR_10 PF13374.6 CCC69425.1 - 0.17 11.8 18.0 0.76 9.7 0.1 7.9 9 0 0 9 9 9 0 Tetratricopeptide repeat PEX11 PF05648.14 CCC69426.1 - 2.2e-59 200.7 2.8 2.5e-59 200.5 2.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) LCM PF04072.14 CCC69427.1 - 2e-28 99.6 0.0 3.6e-28 98.8 0.0 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_3 PF13415.6 CCC69427.1 - 6.3e-09 35.9 0.1 0.024 14.9 0.0 4.5 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_6 PF13964.6 CCC69427.1 - 7e-09 35.7 1.4 0.00075 19.7 0.0 4.7 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.25 CCC69427.1 - 1.7e-07 30.7 0.0 0.0014 18.2 0.0 3.8 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 CCC69427.1 - 2.3e-07 30.6 0.1 0.0014 18.5 0.0 5.0 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 CCC69427.1 - 5.3e-07 29.5 0.0 0.019 15.0 0.0 4.4 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_2 PF07646.15 CCC69427.1 - 0.0053 16.7 2.8 2 8.5 0.0 4.1 4 0 0 4 4 4 1 Kelch motif CDC50 PF03381.15 CCC69428.1 - 4.3e-81 272.5 0.5 5.8e-81 272.1 0.5 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PBP1_TM PF14812.6 CCC69428.1 - 0.61 10.5 4.1 1.4 9.4 4.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aminotran_3 PF00202.21 CCC69429.1 - 2.6e-127 424.9 0.1 3.1e-127 424.6 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III PucR PF07905.11 CCC69429.1 - 0.016 15.5 0.0 0.87 9.9 0.0 3.1 3 0 0 3 3 3 0 Purine catabolism regulatory protein-like family PIG-H PF10181.9 CCC69429.1 - 0.16 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component Mito_carr PF00153.27 CCC69430.1 - 1.4e-67 223.7 2.7 2.9e-26 91.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein BATS PF06968.13 CCC69431.1 - 2.6e-22 78.7 0.0 6.7e-22 77.4 0.0 1.7 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 CCC69431.1 - 2.8e-16 60.4 0.2 7.9e-15 55.6 0.1 2.1 2 0 0 2 2 2 1 Radical SAM superfamily INPP5B_PH PF16776.5 CCC69431.1 - 0.0053 16.5 0.0 0.0092 15.7 0.0 1.4 1 0 0 1 1 1 1 Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain IF4E PF01652.18 CCC69432.1 - 2.2e-55 186.8 0.3 2.6e-55 186.6 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.32 CCC69433.1 - 1.4e-10 41.5 2.0 0.0021 18.9 0.1 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 CCC69433.1 - 1.5e-09 37.3 2.0 2.4e-09 36.7 1.3 1.7 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 CCC69433.1 - 0.00086 19.5 5.1 0.0025 18.1 5.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CCC69433.1 - 0.0081 16.5 3.7 0.0081 16.5 3.7 2.1 1 1 1 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 CCC69433.1 - 0.018 14.9 1.0 0.018 14.9 1.0 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Na_Ca_ex_C PF16494.5 CCC69433.1 - 0.087 13.3 0.9 0.22 12.0 0.9 1.8 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain MFS_1 PF07690.16 CCC69434.1 - 1e-19 70.7 44.8 3.7e-13 49.1 11.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.32 CCC69435.1 - 2.8e-31 107.1 15.8 4e-06 27.5 0.0 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC69435.1 - 8.7e-18 64.4 0.7 0.0019 18.5 0.0 5.8 2 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCC69435.1 - 1.7e-06 28.0 2.2 0.00028 20.8 1.4 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCC69435.1 - 0.00039 19.5 1.4 1.1 8.2 0.0 4.0 1 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CCC69435.1 - 0.0011 17.7 0.4 0.16 10.6 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 6PF2K PF01591.18 CCC69436.1 - 4.4e-41 140.6 0.1 7.7e-41 139.8 0.1 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.6 CCC69436.1 - 5.9e-06 26.5 0.0 1e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 CCC69436.1 - 1.9e-05 24.3 0.0 2.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 CCC69436.1 - 0.019 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.6 CCC69436.1 - 0.08 13.5 0.0 0.17 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CCC69436.1 - 0.16 12.3 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Med7 PF05983.11 CCC69437.1 - 3.1e-66 223.1 7.8 3.6e-66 222.9 7.8 1.0 1 0 0 1 1 1 1 MED7 protein YqzE PF14038.6 CCC69437.1 - 0.0018 18.3 0.6 0.0086 16.1 0.3 2.1 2 0 0 2 2 2 1 YqzE-like protein cwf21 PF08312.12 CCC69437.1 - 0.037 14.2 4.1 0.037 14.2 4.1 2.5 3 0 0 3 3 3 0 cwf21 domain RICTOR_M PF14666.6 CCC69437.1 - 0.099 12.4 1.1 0.26 11.1 1.1 1.7 1 1 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, middle domain CREPT PF16566.5 CCC69437.1 - 1.8 8.7 7.4 0.15 12.2 1.5 2.2 2 1 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour zf-rbx1 PF12678.7 CCC69438.1 - 8.7e-24 83.6 13.7 1.5e-23 82.8 13.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCC69438.1 - 1.9e-17 63.1 10.3 2.4e-17 62.8 10.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 CCC69438.1 - 5.2e-06 26.7 14.2 0.00028 21.2 14.2 2.4 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CCC69438.1 - 0.00052 19.8 12.3 0.0032 17.3 12.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCC69438.1 - 0.00084 19.1 4.3 0.00084 19.1 4.3 2.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 CCC69438.1 - 0.0029 17.3 1.2 0.0029 17.3 1.2 2.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 CCC69438.1 - 0.094 12.9 6.9 0.18 12.0 0.4 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 CCC69438.1 - 0.39 10.6 11.1 1.2 9.1 4.8 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCC69438.1 - 0.47 10.5 10.1 2.3 8.3 10.1 2.2 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.8 CCC69438.1 - 0.53 10.5 9.5 3.1 8.1 9.8 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 CCC69438.1 - 1.9 8.2 14.8 1e+02 2.7 14.8 2.4 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 CCC69438.1 - 2.6 8.4 12.2 30 5.0 12.2 2.3 1 1 0 1 1 1 0 RING-like domain zf-RING_UBOX PF13445.6 CCC69438.1 - 2.7 8.1 10.3 9.3 6.4 10.0 2.1 1 1 0 1 1 1 0 RING-type zinc-finger TPR_8 PF13181.6 CCC69439.1 - 1.4e-09 37.4 1.3 0.0085 16.2 0.0 5.2 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCC69439.1 - 1.7e-08 33.9 1.0 0.033 14.3 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCC69439.1 - 1.1e-07 32.0 0.6 0.3 12.0 0.1 5.8 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCC69439.1 - 3.8e-07 30.5 0.8 0.086 13.4 0.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCC69439.1 - 6.7e-06 26.6 0.6 0.51 11.0 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 CCC69439.1 - 0.00036 20.2 2.4 1.7 8.6 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 CCC69439.1 - 0.00049 20.3 2.1 0.3 11.4 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 CCC69439.1 - 0.0012 19.1 8.4 0.034 14.5 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat ChAPs PF09295.10 CCC69439.1 - 0.023 13.7 1.9 0.071 12.1 0.1 2.4 3 0 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) APC1_C PF18122.1 CCC69439.1 - 0.025 14.5 0.3 0.11 12.5 0.1 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain TPR_11 PF13414.6 CCC69439.1 - 0.026 14.2 0.0 1.6 8.5 0.0 3.6 3 1 1 4 4 4 0 TPR repeat TPR_9 PF13371.6 CCC69439.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.0 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 CCC69439.1 - 0.13 12.3 2.4 11 6.3 0.1 4.3 5 1 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC69439.1 - 3.1 8.1 9.2 7.5 6.9 1.2 4.2 4 2 1 5 5 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 CCC69439.1 - 5.3 7.1 6.6 0.78 9.7 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat tRNA_anti-codon PF01336.25 CCC69440.1 - 3.3e-10 39.8 0.2 5.9e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.11 CCC69440.1 - 3.1e-08 34.2 0.4 1.6e-07 32.0 0.0 2.2 3 0 0 3 3 3 1 Replication protein A C terminal tRNA_anti_2 PF13742.6 CCC69440.1 - 0.018 15.3 0.1 0.033 14.4 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain HTH_IclR PF09339.10 CCC69440.1 - 0.028 14.2 0.0 0.048 13.5 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain CDC24_OB3 PF17244.2 CCC69440.1 - 0.069 12.8 0.8 0.16 11.7 0.1 1.8 2 0 0 2 2 2 0 Cell division control protein 24, OB domain 3 Glyco_hydro_72 PF03198.14 CCC69441.1 - 7.8e-134 445.9 0.4 1e-133 445.5 0.4 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_cc PF11790.8 CCC69441.1 - 0.07 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core DNA_pol3_a_NII PF11490.8 CCC69441.1 - 0.19 11.6 1.1 1.7 8.6 0.1 2.4 3 0 0 3 3 3 0 DNA polymerase III polC-type N-terminus II CorA PF01544.18 CCC69442.1 - 7.1e-40 137.1 2.3 8.1e-38 130.4 0.2 2.9 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein UPF0220 PF05255.11 CCC69443.1 - 2.6e-71 238.5 3.4 3e-71 238.3 3.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF202 PF02656.15 CCC69443.1 - 6.8 7.2 8.3 5.9 7.4 3.4 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) Pkinase PF00069.25 CCC69444.1 - 6.9e-58 196.1 0.0 8.9e-58 195.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69444.1 - 8.2e-30 103.9 0.0 1.1e-29 103.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC69444.1 - 2.5e-06 27.0 0.0 3.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 CCC69444.1 - 0.00067 19.7 0.0 0.0011 19.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 CCC69444.1 - 0.0026 17.1 0.1 0.0037 16.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 CCC69444.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Ribosomal_L23eN PF03939.13 CCC69445.1 - 2.1e-19 69.4 10.2 2.1e-19 69.4 10.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 CCC69445.1 - 3.4e-16 59.4 3.8 3.4e-16 59.4 3.8 2.8 2 2 0 2 2 2 1 Ribosomal protein L23 Ldh_1_N PF00056.23 CCC69446.1 - 4e-42 143.6 0.1 6e-42 143.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 CCC69446.1 - 7.7e-42 143.1 0.0 1.2e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Semialdhyde_dh PF01118.24 CCC69446.1 - 0.0045 17.4 0.0 0.24 11.8 0.0 2.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GATA PF00320.27 CCC69447.1 - 2.4e-10 39.8 2.8 3.9e-10 39.2 2.8 1.4 1 0 0 1 1 1 1 GATA zinc finger TRM13 PF05206.14 CCC69448.1 - 4.4e-81 272.3 4.4 7.7e-81 271.5 4.4 1.4 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 CCC69448.1 - 8.6e-15 54.2 1.8 2.2e-14 52.9 1.8 1.8 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 CCC69448.1 - 8e-13 48.0 5.5 3e-12 46.2 1.2 2.7 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_31 PF13847.6 CCC69448.1 - 0.019 14.8 0.3 0.18 11.6 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain UPF0020 PF01170.18 CCC69449.1 - 2.9e-10 40.2 0.0 1.4e-08 34.7 0.0 2.6 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 CCC69449.1 - 0.0013 18.5 0.0 0.064 12.9 0.0 2.6 2 1 0 2 2 2 2 DNA methylase RRM_1 PF00076.22 CCC69450.1 - 1.3e-33 114.6 0.5 7.6e-17 60.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC69450.1 - 7.3e-12 45.2 0.2 4.2e-06 26.8 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif OB_RNB PF08206.11 CCC69450.1 - 0.065 12.9 0.2 8.2 6.2 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain DUF4199 PF13858.6 CCC69450.1 - 2.2 8.7 5.2 5.6 7.3 5.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Nramp PF01566.18 CCC69451.1 - 5.8e-89 298.5 25.1 5.8e-89 298.5 25.1 2.4 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein DUF5488 PF17590.2 CCC69451.1 - 0.045 13.5 1.1 0.12 12.1 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5488) Dimer_Tnp_hAT PF05699.14 CCC69452.1 - 1.5e-06 27.9 0.1 6e-06 26.0 0.1 2.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CCC69452.1 - 0.04 13.9 2.6 0.12 12.4 2.6 1.9 1 0 0 1 1 1 0 BED zinc finger zinc_ribbon_4 PF13717.6 CCC69452.1 - 0.15 12.0 0.9 0.33 10.9 0.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_S19e PF01090.19 CCC69453.1 - 2.2e-53 179.6 0.1 2.5e-53 179.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L18 PF17135.4 CCC69454.1 - 3.5e-63 212.4 3.1 3.9e-63 212.2 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 CCC69454.1 - 0.0011 19.6 0.2 0.0036 18.0 0.2 1.9 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TPR_12 PF13424.6 CCC69455.1 - 0.075 13.3 0.3 0.17 12.2 0.3 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat GCR1_C PF12550.8 CCC69456.1 - 5.2e-25 87.6 0.2 9.5e-25 86.7 0.2 1.4 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes EPL1 PF10513.9 CCC69456.1 - 0.043 14.2 3.5 0.076 13.4 3.5 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like NTP_transf_2 PF01909.23 CCC69457.1 - 3.2e-20 72.2 0.2 2.8e-19 69.2 0.0 2.6 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 CCC69457.1 - 7e-16 58.2 0.0 7e-16 58.2 0.0 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase DNA_pol_B_palm PF14792.6 CCC69457.1 - 0.0048 17.1 0.0 0.014 15.6 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta palm Polbeta PF18765.1 CCC69457.1 - 0.014 15.5 0.7 0.041 14.0 0.0 2.2 2 0 0 2 2 2 0 Polymerase beta, Nucleotidyltransferase RF-1 PF00472.20 CCC69458.1 - 1.5e-18 66.8 0.4 2.1e-18 66.4 0.4 1.1 1 0 0 1 1 1 1 RF-1 domain PBD PF00786.28 CCC69459.1 - 8.6e-13 48.4 0.6 1.4e-12 47.7 0.6 1.4 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.29 CCC69459.1 - 2.6e-07 31.1 0.1 4.4e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CCC69459.1 - 0.0017 18.8 0.0 0.0022 18.4 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain FPN1 PF06963.12 CCC69459.1 - 0.077 11.5 0.0 0.092 11.3 0.0 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) RabGAP-TBC PF00566.18 CCC69460.1 - 2.5e-44 151.5 3.4 2.6e-31 109.0 0.1 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF1053 PF06327.14 CCC69460.1 - 0.044 14.3 0.8 0.24 12.0 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) Get5_bdg PF16843.5 CCC69461.1 - 2e-28 97.6 0.7 6.3e-28 96.0 0.4 2.0 2 0 0 2 2 2 1 Binding domain to Get4 on Get5, Golgi to ER traffic protein Get5_C PF18514.1 CCC69461.1 - 2.8e-14 52.5 0.7 2.8e-14 52.5 0.7 1.9 2 0 0 2 2 2 1 Get5 C-terminal domain ubiquitin PF00240.23 CCC69461.1 - 1.3e-06 28.1 0.2 1.3e-06 28.1 0.2 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.6 CCC69461.1 - 0.00033 20.7 0.1 0.00059 19.9 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Blt1_C PF17183.4 CCC69461.1 - 0.0017 17.9 0.1 0.0031 17.1 0.1 1.4 1 0 0 1 1 1 1 Get5 carboxyl domain DUF4786 PF16027.5 CCC69461.1 - 0.015 15.8 2.7 0.038 14.6 2.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4786) DUF2407 PF10302.9 CCC69461.1 - 0.064 13.8 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Erf4 PF10256.9 CCC69462.1 - 1.4e-32 112.2 0.0 1.8e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Lambda_Bor PF06291.11 CCC69462.1 - 0.17 11.9 0.0 0.27 11.3 0.0 1.3 1 0 0 1 1 1 0 Bor protein Cyclin_N PF00134.23 CCC69463.1 - 6.3e-14 51.8 0.1 9e-14 51.3 0.1 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCC69463.1 - 1.4e-05 25.6 0.0 2.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin HLH PF00010.26 CCC69464.1 - 0.0012 18.8 6.2 0.0023 17.8 0.4 2.5 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain DUF1751 PF08551.10 CCC69465.1 - 2.7e-26 92.0 1.6 2.7e-26 92.0 1.6 2.5 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) DUF3566 PF12089.8 CCC69465.1 - 0.48 10.8 11.0 0.14 12.5 0.5 3.0 3 0 0 3 3 3 0 Transmembrane domain of unknown function (DUF3566) Sugar_tr PF00083.24 CCC69466.1 - 6.2e-138 460.4 26.3 7.4e-138 460.2 26.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC69466.1 - 3.8e-31 108.3 31.5 1.5e-30 106.3 25.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCC69466.1 - 8.8e-06 24.4 5.2 8.8e-06 24.4 5.2 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 CCC69466.1 - 0.0005 18.6 0.5 0.001 17.6 0.5 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector PTS_2-RNA PF01885.16 CCC69467.1 - 1.1e-59 201.5 1.7 1.3e-59 201.3 1.7 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PARP PF00644.20 CCC69467.1 - 0.019 14.5 0.6 0.038 13.6 0.6 1.5 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain Fungal_trans PF04082.18 CCC69468.1 - 3.5e-24 85.3 3.9 3.5e-24 85.3 3.9 2.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC69468.1 - 4.1e-10 39.6 14.0 7.4e-10 38.8 14.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AveC_like PF17198.4 CCC69468.1 - 0.094 12.1 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Spirocyclase AveC-like UPF0506 PF11703.8 CCC69468.1 - 0.37 11.2 6.8 0.96 9.9 6.8 1.6 1 0 0 1 1 1 0 UPF0506 Bunya_G2 PF03563.13 CCC69469.1 - 5.1 6.3 10.2 7.7 5.7 10.2 1.3 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Vps23_core PF09454.10 CCC69470.1 - 1.4e-22 79.4 1.0 2.9e-22 78.4 0.3 1.9 2 0 0 2 2 2 1 Vps23 core domain DUF1517 PF07466.11 CCC69470.1 - 0.0059 16.8 0.5 0.0094 16.1 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) UPF0449 PF15136.6 CCC69470.1 - 5 7.6 6.5 25 5.4 6.5 2.2 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 ALS_ss_C PF10369.9 CCC69471.1 - 4.7e-16 58.8 0.0 1.8e-15 56.9 0.0 2.0 1 0 0 1 1 1 1 Small subunit of acetolactate synthase ACT PF01842.25 CCC69471.1 - 1.1e-13 50.6 0.1 2.5e-13 49.5 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.6 CCC69471.1 - 4.9e-08 32.7 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 ACT domain Limkain-b1 PF11608.8 CCC69471.1 - 0.00065 19.7 0.0 0.0045 17.0 0.0 2.3 4 0 0 4 4 4 1 Limkain b1 ACT_4 PF13291.6 CCC69471.1 - 0.045 14.4 0.1 0.8 10.3 0.0 2.3 2 0 0 2 2 2 0 ACT domain DUF1325 PF07039.11 CCC69472.1 - 4.3e-38 130.4 0.0 8.1e-38 129.5 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 CCC69472.1 - 6.8e-06 25.8 0.0 1.8e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain Agenet PF05641.12 CCC69472.1 - 0.00028 21.3 0.1 0.072 13.6 0.0 2.5 2 0 0 2 2 2 1 Agenet domain DUF1474 PF07342.11 CCC69472.1 - 0.0068 16.9 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1474) DUF4537 PF15057.6 CCC69472.1 - 0.014 15.4 0.0 0.031 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) PilZ PF07238.14 CCC69472.1 - 0.015 15.6 0.0 0.16 12.3 0.0 2.3 2 1 0 2 2 2 0 PilZ domain KxDL PF10241.9 CCC69472.1 - 0.015 15.5 0.3 0.027 14.7 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein RRM_1 PF00076.22 CCC69473.1 - 7.4e-62 205.1 0.1 9.9e-22 76.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_Rrp7 PF17799.1 CCC69473.1 - 2.6e-05 24.1 0.0 0.75 9.6 0.0 3.2 3 0 0 3 3 3 3 Rrp7 RRM-like N-terminal domain RRM_9 PF18444.1 CCC69473.1 - 6.7e-05 22.7 0.1 0.89 9.5 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_5 PF13893.6 CCC69473.1 - 0.00016 21.3 0.0 0.04 13.5 0.0 2.7 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCC69473.1 - 0.00038 20.3 0.0 0.17 11.7 0.0 3.1 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CCC69473.1 - 0.0019 18.2 0.1 0.017 15.1 0.0 2.5 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif BRAP2 PF07576.12 CCC69473.1 - 0.031 14.5 0.0 12 6.2 0.0 2.4 2 0 0 2 2 2 0 BRCA1-associated protein 2 Limkain-b1 PF11608.8 CCC69473.1 - 0.073 13.2 0.1 17 5.6 0.0 2.8 3 0 0 3 3 3 0 Limkain b1 RRM_7 PF16367.5 CCC69473.1 - 0.082 13.0 0.0 4 7.6 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif DUF3507 PF12015.8 CCC69474.1 - 3.7e-52 176.7 0.3 7.6e-52 175.7 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) Dcc1 PF09724.9 CCC69475.1 - 6.2e-81 272.3 0.1 7.2e-81 272.1 0.1 1.0 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 Aminotran_5 PF00266.19 CCC69476.1 - 5.4e-100 334.9 0.0 7.1e-100 334.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 CCC69476.1 - 1.9e-10 40.6 0.0 2.9e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 CCC69476.1 - 4.3e-08 32.7 0.0 7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CCC69476.1 - 5.7e-08 32.5 0.1 2.1e-07 30.6 0.3 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 CCC69476.1 - 1.5e-05 24.0 0.1 2.3e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 CCC69476.1 - 9.6e-05 21.1 0.2 0.00017 20.2 0.2 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Styelin PF17562.2 CCC69476.1 - 0.15 12.4 1.8 20 5.6 0.0 2.7 3 0 0 3 3 3 0 Styelin Iso_dh PF00180.20 CCC69477.1 - 2.8e-123 411.5 0.0 3.2e-123 411.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DNA_ligase_aden PF01653.18 CCC69477.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain RFX_DNA_binding PF02257.15 CCC69478.1 - 4.5e-33 113.7 0.0 1.5e-32 112.0 0.0 2.0 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.16 CCC69478.1 - 0.0063 17.0 0.0 0.04 14.4 0.0 2.4 1 0 0 1 1 1 1 Poxvirus D5 protein-like DnaJ_C PF01556.18 CCC69479.1 - 3.8e-35 121.2 0.2 7e-35 120.3 0.2 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCC69479.1 - 2.9e-22 78.6 1.1 5e-22 77.8 1.1 1.4 1 0 0 1 1 1 1 DnaJ domain DKCLD PF08068.12 CCC69480.1 - 4.6e-32 109.9 0.2 4.9e-31 106.6 0.3 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 CCC69480.1 - 5e-23 81.0 0.4 1e-22 80.0 0.4 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 CCC69480.1 - 2.5e-20 73.4 7.4 4.2e-19 69.4 0.0 4.0 2 1 0 2 2 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 CCC69480.1 - 8.9e-20 70.4 1.1 1.8e-19 69.4 1.1 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 CCC69480.1 - 0.02 15.1 0.0 0.053 13.8 0.0 1.7 1 0 0 1 1 1 0 UPF0113 PUA domain CENP-N PF05238.13 CCC69480.1 - 0.31 10.3 12.1 0.44 9.8 12.1 1.3 1 0 0 1 1 1 0 Kinetochore protein CHL4 like GAGA_bind PF06217.12 CCC69480.1 - 0.75 10.0 20.2 1.1 9.5 20.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Rrn6 PF10214.9 CCC69480.1 - 0.81 8.1 11.0 0.97 7.9 11.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor EOS1 PF12326.8 CCC69480.1 - 2.2 8.2 5.2 3.4 7.6 5.2 1.4 1 0 0 1 1 1 0 N-glycosylation protein TMEM223 PF14640.6 CCC69480.1 - 3.9 7.6 0.0 3.9 7.6 0.0 2.5 2 1 0 2 2 1 0 Transmembrane protein 223 VIR_N PF15912.5 CCC69480.1 - 5.8 6.4 19.1 8.5 5.9 19.1 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF2151 PF10221.9 CCC69480.1 - 8.4 4.8 19.7 11 4.5 19.7 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator UvrD-helicase PF00580.21 CCC69481.1 - 5.2e-39 134.6 3.6 1.4e-20 74.1 2.0 2.8 2 2 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 CCC69481.1 - 1.1e-28 100.5 0.0 5.6e-28 98.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 CCC69481.1 - 1.4e-27 97.1 2.2 3.2e-26 92.6 0.0 3.3 2 2 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_11 PF13086.6 CCC69481.1 - 3.6e-11 43.3 0.1 1.2e-10 41.6 0.1 1.9 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 CCC69481.1 - 6.3e-10 38.7 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 CCC69481.1 - 1.1e-09 38.4 0.0 3.5e-05 23.6 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.15 CCC69481.1 - 9.5e-05 22.5 0.1 0.00092 19.2 0.1 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCC69481.1 - 0.0017 18.1 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCC69481.1 - 0.0027 18.0 0.1 2.1 8.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain Rac1 PF09632.10 CCC69481.1 - 0.0027 16.9 0.0 0.0063 15.7 0.0 1.6 1 0 0 1 1 1 1 Rac1-binding domain DUF2075 PF09848.9 CCC69481.1 - 0.0028 17.0 0.5 0.57 9.4 0.3 2.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 CCC69481.1 - 0.16 11.8 0.0 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 Helicase AAA_24 PF13479.6 CCC69481.1 - 0.19 11.4 1.1 1.1 8.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain PBP_dimer PF03717.15 CCC69481.1 - 0.24 11.7 1.7 0.47 10.8 1.7 1.4 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain AAA PF00004.29 CCC69481.1 - 3.4 8.1 5.2 55 4.2 0.3 3.7 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) HlyIII PF03006.20 CCC69482.1 - 2.9e-17 63.1 20.2 3.6e-17 62.9 20.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related Pox_A14 PF05767.12 CCC69482.1 - 8.6 6.6 10.9 1.1 9.4 2.8 3.1 1 1 3 4 4 4 0 Poxvirus virion envelope protein A14 Pkinase PF00069.25 CCC69484.1 - 2e-63 214.3 0.0 3.2e-63 213.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69484.1 - 1.4e-35 122.8 0.0 2.2e-35 122.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC69484.1 - 3.6e-07 29.8 0.0 1e-05 25.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CCC69484.1 - 0.00019 21.1 0.5 0.14 11.7 0.1 2.5 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 CCC69484.1 - 0.00033 19.5 0.7 0.0079 15.0 0.0 2.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CCC69484.1 - 0.0075 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_LMP1 PF05297.11 CCC69484.1 - 0.0094 15.2 6.8 0.018 14.3 6.8 1.4 1 0 0 1 1 1 1 Herpesvirus latent membrane protein 1 (LMP1) Haspin_kinase PF12330.8 CCC69484.1 - 0.012 14.6 0.1 0.012 14.6 0.1 2.8 3 0 0 3 3 3 0 Haspin like kinase domain RIO1 PF01163.22 CCC69484.1 - 0.036 13.7 0.4 0.13 11.8 0.0 2.0 1 1 0 2 2 2 0 RIO1 family APH PF01636.23 CCC69484.1 - 0.042 13.8 0.0 0.075 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M16_C PF05193.21 CCC69485.1 - 2.3e-14 53.8 0.0 1.4e-13 51.3 0.0 2.4 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCC69485.1 - 1.2e-08 35.1 0.0 4.7e-08 33.2 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) tRNA-synt_1b PF00579.25 CCC69486.1 - 3.1e-18 66.1 0.0 2.2e-12 46.9 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Sec7 PF01369.20 CCC69486.1 - 0.084 12.5 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Sec7 domain AAA_33 PF13671.6 CCC69487.1 - 6e-08 33.0 0.0 0.00024 21.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CCC69487.1 - 3.8e-06 26.9 0.1 1.1e-05 25.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCC69487.1 - 1.3e-05 25.6 0.0 1.8e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CCC69487.1 - 3.4e-05 24.4 0.1 0.00014 22.4 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 CCC69487.1 - 6.5e-05 23.2 0.0 0.00013 22.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 CCC69487.1 - 0.00021 21.3 0.1 0.00036 20.5 0.1 1.3 1 0 0 1 1 1 1 Rad17 P-loop domain AAA PF00004.29 CCC69487.1 - 0.00031 21.2 0.0 0.0006 20.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CCC69487.1 - 0.00035 20.9 0.2 0.00092 19.6 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_7 PF12775.7 CCC69487.1 - 0.00075 19.1 0.0 0.0027 17.2 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_11 PF13086.6 CCC69487.1 - 0.00087 19.1 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.6 CCC69487.1 - 0.001 19.2 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain PRK PF00485.18 CCC69487.1 - 0.0024 17.6 0.1 1.2 8.9 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 CCC69487.1 - 0.0028 16.9 0.0 0.0049 16.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.12 CCC69487.1 - 0.0033 16.7 0.0 0.0059 15.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 CCC69487.1 - 0.0039 17.6 0.0 0.028 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CCC69487.1 - 0.0053 17.3 0.2 0.013 16.0 0.2 1.7 1 1 0 1 1 1 1 ABC transporter AAA_30 PF13604.6 CCC69487.1 - 0.0077 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 CCC69487.1 - 0.0086 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain ADK PF00406.22 CCC69487.1 - 0.0086 16.2 0.1 0.28 11.3 0.0 2.4 2 0 0 2 2 2 1 Adenylate kinase KTI12 PF08433.10 CCC69487.1 - 0.0089 15.5 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 TIP49 PF06068.13 CCC69487.1 - 0.009 15.2 0.0 0.016 14.4 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain Septin PF00735.18 CCC69487.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_29 PF13555.6 CCC69487.1 - 0.014 15.1 0.0 0.043 13.5 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 CCC69487.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 CCC69487.1 - 0.015 15.1 0.0 0.039 13.7 0.0 1.7 2 0 0 2 2 1 0 Holliday junction DNA helicase RuvB P-loop domain SRPRB PF09439.10 CCC69487.1 - 0.017 14.6 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Mg_chelatase PF01078.21 CCC69487.1 - 0.022 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI MMR_HSR1 PF01926.23 CCC69487.1 - 0.023 14.8 0.0 0.046 13.8 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 CCC69487.1 - 0.026 14.2 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 CCC69487.1 - 0.029 14.1 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase Ploopntkinase3 PF18751.1 CCC69487.1 - 0.029 14.3 0.0 0.078 12.9 0.0 1.8 2 0 0 2 2 1 0 P-loop Nucleotide Kinase3 AAA_25 PF13481.6 CCC69487.1 - 0.04 13.5 0.0 0.13 11.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 CCC69487.1 - 0.043 13.8 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NTPase_1 PF03266.15 CCC69487.1 - 0.046 13.6 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.6 CCC69487.1 - 0.046 14.0 0.0 0.075 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CCC69487.1 - 0.051 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea DNA_pol3_delta2 PF13177.6 CCC69487.1 - 0.051 13.3 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase III, delta subunit APS_kinase PF01583.20 CCC69487.1 - 0.052 13.4 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF3987 PF13148.6 CCC69487.1 - 0.056 12.5 0.0 0.082 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_PrkA PF08298.11 CCC69487.1 - 0.064 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain NACHT PF05729.12 CCC69487.1 - 0.067 13.1 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 CCC69487.1 - 0.067 13.5 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CCC69487.1 - 0.076 12.7 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 IstB-like ATP binding protein 6PF2K PF01591.18 CCC69487.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase RsgA_GTPase PF03193.16 CCC69487.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase cobW PF02492.19 CCC69487.1 - 0.1 12.1 0.0 0.31 10.6 0.0 1.7 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CobU PF02283.16 CCC69487.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase PPV_E1_C PF00519.17 CCC69487.1 - 0.17 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase Thioredoxin PF00085.20 CCC69488.1 - 7.5e-12 45.2 0.2 3.1e-11 43.2 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.6 CCC69488.1 - 0.01 16.1 0.2 0.028 14.7 0.2 1.7 1 0 0 1 1 1 0 Thioredoxin-like PLDc_2 PF13091.6 CCC69489.1 - 2.5e-13 50.1 0.0 9e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 CCC69489.1 - 1.7e-08 34.3 3.2 0.00059 19.9 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PQ-loop PF04193.14 CCC69490.1 - 2.9e-05 23.8 16.7 0.00033 20.4 2.9 3.8 3 1 0 3 3 3 3 PQ loop repeat Rer1 PF03248.13 CCC69491.1 - 2.3e-72 242.3 6.9 2.6e-72 242.1 6.9 1.0 1 0 0 1 1 1 1 Rer1 family eRF1_2 PF03464.15 CCC69492.1 - 1.9e-26 93.0 0.4 3.5e-26 92.1 0.4 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CCC69492.1 - 1.9e-22 79.8 0.0 6.2e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CCC69492.1 - 9.9e-22 77.3 0.7 1.8e-21 76.5 0.7 1.4 1 0 0 1 1 1 1 eRF1 domain 1 CAMSAP_CKK PF08683.11 CCC69492.1 - 0.012 15.7 1.1 0.021 15.0 0.6 1.7 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated Ribosomal_L32p PF01783.23 CCC69493.1 - 4.9e-13 49.1 4.4 9.3e-13 48.2 4.4 1.5 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.15 CCC69493.1 - 0.017 14.7 0.8 0.033 13.8 0.8 1.4 1 0 0 1 1 1 0 RecR protein zf-ribbon_3 PF13248.6 CCC69493.1 - 0.047 13.1 1.8 0.081 12.4 1.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain FMN_red PF03358.15 CCC69494.1 - 4.8e-09 36.1 0.0 7.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.25 CCC69494.1 - 0.00011 22.4 0.4 0.00039 20.6 0.4 1.9 1 1 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.17 CCC69494.1 - 0.0057 16.4 0.3 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin-like fold PcfK PF14058.6 CCC69494.1 - 0.017 15.4 3.5 0.029 14.6 3.5 1.2 1 0 0 1 1 1 0 PcfK-like protein Flavodoxin_5 PF12724.7 CCC69494.1 - 0.094 13.0 0.1 4.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Flavodoxin domain MFA1_2 PF17317.2 CCC69494.1 - 6.6 6.6 5.5 18 5.2 0.1 2.5 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 Citrate_synt PF00285.21 CCC69495.1 - 5e-101 338.4 0.0 6.2e-101 338.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DSPc PF00782.20 CCC69496.1 - 1e-24 86.9 0.6 5.2e-18 65.1 0.1 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain HECT_2 PF09814.9 CCC69496.1 - 0.0025 16.8 0.7 0.017 14.0 0.0 2.0 2 0 0 2 2 2 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Y_phosphatase PF00102.27 CCC69496.1 - 0.0028 17.2 0.0 0.0047 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Yippee-Mis18 PF03226.14 CCC69496.1 - 0.009 16.2 1.0 0.059 13.6 1.0 2.2 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PTPlike_phytase PF14566.6 CCC69496.1 - 0.015 15.5 0.0 0.026 14.6 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Elf1 PF05129.13 CCC69496.1 - 0.02 14.9 0.2 3.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.6 CCC69496.1 - 0.32 11.0 3.5 2.2 8.3 0.3 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Apc15p PF05841.11 CCC69497.1 - 1.4e-29 103.4 0.3 1.4e-29 103.4 0.3 2.0 1 1 1 2 2 2 1 Apc15p protein Vmethyltransf_C PF08456.10 CCC69497.1 - 0.017 14.7 0.2 0.19 11.3 0.0 2.3 3 0 0 3 3 3 0 Viral methyltransferase C-terminal RNA_pol_3_Rpc31 PF11705.8 CCC69497.1 - 0.054 13.7 5.8 0.066 13.4 2.7 2.0 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 DARPP-32 PF05395.12 CCC69497.1 - 4 7.6 7.2 11 6.2 6.1 2.0 2 0 0 2 2 2 0 Protein phosphatase inhibitor 1/DARPP-32 Npa1 PF11707.8 CCC69498.1 - 1.5e-83 281.0 2.8 1.5e-83 281.0 2.8 2.0 2 0 0 2 2 2 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 CCC69498.1 - 5.6e-51 173.0 0.1 5.6e-51 173.0 0.1 3.3 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 HOIP-UBA PF16678.5 CCC69498.1 - 0.13 12.3 0.5 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 HOIP UBA domain pair DUF5321 PF17254.2 CCC69499.1 - 0.0035 16.8 0.4 0.0093 15.4 0.0 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5321) Bac_DnaA PF00308.18 CCC69499.1 - 0.03 14.1 0.9 0.047 13.5 0.9 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein Fungal_trans PF04082.18 CCC69500.1 - 1.2e-25 90.1 1.1 2.7e-25 88.9 1.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC69500.1 - 0.0055 16.8 6.2 0.011 15.8 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSP1_C PF07462.11 CCC69500.1 - 1.8 7.2 9.8 0.17 10.6 1.2 2.2 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus FF PF01846.19 CCC69501.1 - 2.9e-34 117.0 30.7 6.5e-13 48.6 1.1 7.2 6 1 1 7 7 7 4 FF domain WW PF00397.26 CCC69501.1 - 2.8e-17 62.5 10.5 1e-09 38.3 2.0 2.7 2 0 0 2 2 2 2 WW domain PQQ PF01011.21 CCC69501.1 - 0.056 13.4 1.5 0.94 9.5 0.2 2.7 2 0 0 2 2 2 0 PQQ enzyme repeat Mating_N PF12731.7 CCC69501.1 - 0.12 12.5 0.9 7.1 6.8 0.1 3.4 3 0 0 3 3 3 0 Mating-type protein beta 1 Glyco_hyd_101C PF17451.2 CCC69501.1 - 0.28 11.5 11.7 0.32 11.3 0.2 3.7 3 1 1 4 4 4 0 Glycosyl hydrolase 101 beta sandwich domain Thioredoxin_4 PF13462.6 CCC69501.1 - 2.2 8.4 11.4 0.084 13.0 1.1 3.1 3 0 0 3 3 3 0 Thioredoxin MAS20 PF02064.15 CCC69502.1 - 0.45 10.6 3.8 0.19 11.8 0.7 1.8 1 1 1 2 2 2 0 MAS20 protein import receptor Hyphal_reg_CWP PF11765.8 CCC69503.1 - 7.9e-17 61.2 6.6 1.4e-16 60.4 6.6 1.3 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal zf-Tim10_DDP PF02953.15 CCC69504.1 - 3e-20 71.6 3.8 3.7e-20 71.3 3.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 CCC69504.1 - 0.032 13.9 2.5 0.046 13.4 2.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) G-alpha PF00503.20 CCC69505.1 - 1.5e-111 373.0 10.8 1.8e-111 372.7 10.8 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 CCC69505.1 - 4.2e-15 55.6 0.6 9.4e-10 38.2 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCC69505.1 - 0.0032 16.9 0.4 0.3 10.4 0.1 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Ank_2 PF12796.7 CCC69506.1 - 1.2e-21 77.0 2.5 8.7e-11 42.3 0.3 3.8 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCC69506.1 - 4.9e-21 74.8 3.8 8.2e-09 35.8 0.3 3.5 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 CCC69506.1 - 9.3e-16 57.5 9.1 5.4e-06 26.6 0.0 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 CCC69506.1 - 5.8e-14 50.8 7.8 0.0044 17.4 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 CCC69506.1 - 3.9e-10 39.8 1.0 7.7e-06 26.1 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) TUG-UBL1 PF11470.8 CCC69507.1 - 2.2e-23 82.3 1.3 8.3e-23 80.4 0.6 2.5 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 CCC69507.1 - 6.9e-15 55.0 0.4 2.1e-14 53.5 0.1 2.0 2 0 0 2 2 2 1 UBX domain PPR_3 PF13812.6 CCC69508.1 - 2.8e-05 24.1 3.2 0.52 10.4 0.0 4.9 5 0 0 5 5 5 3 Pentatricopeptide repeat domain ATP13 PF12921.7 CCC69508.1 - 0.0011 18.8 1.6 0.52 10.2 0.0 4.1 3 1 1 4 4 4 2 Mitochondrial ATPase expression PPR_2 PF13041.6 CCC69508.1 - 0.0073 16.5 0.4 4.3 7.6 0.0 3.9 4 0 0 4 4 4 2 PPR repeat family SURF6 PF04935.12 CCC69509.1 - 1.3e-44 152.4 57.1 1.3e-44 152.4 57.1 3.1 2 1 0 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 CCC69509.1 - 6.7e-13 49.0 3.5 6.7e-13 49.0 3.5 8.4 5 3 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 Kinesin PF00225.23 CCC69510.1 - 1.8e-18 66.6 8.6 1.5e-13 50.4 0.0 3.5 2 2 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 CCC69510.1 - 0.003 17.5 0.0 0.003 17.5 0.0 2.4 2 1 0 2 2 2 1 Microtubule binding Tht1 PF04163.12 CCC69511.1 - 4.9e-43 147.7 26.4 1.3e-37 129.8 12.6 2.2 1 1 1 2 2 2 2 Tht1-like nuclear fusion protein DASH_Dam1 PF08653.10 CCC69511.1 - 0.08 12.8 1.1 0.29 11.0 0.1 2.6 2 0 0 2 2 2 0 DASH complex subunit Dam1 Latarcin PF10279.9 CCC69511.1 - 0.12 12.7 1.0 1.3 9.5 0.3 2.7 2 1 1 3 3 3 0 Latarcin precursor DUF1319 PF07028.11 CCC69511.1 - 0.78 10.0 5.5 0.6 10.4 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1319) AEP1 PF17049.5 CCC69512.1 - 3.8e-135 451.0 20.3 4.8e-135 450.7 20.3 1.1 1 0 0 1 1 1 1 ATPase expression protein 1 RapH_N PF18801.1 CCC69512.1 - 0.11 12.6 0.8 0.54 10.4 0.0 2.6 2 0 0 2 2 2 0 response regulator aspartate phosphatase H, N terminal SUR7 PF06687.12 CCC69513.1 - 2.7e-20 72.9 16.8 3.6e-20 72.5 16.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF1003 PF06210.11 CCC69513.1 - 1.2 9.2 3.6 3.7 7.7 3.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Fasciclin PF02469.22 CCC69515.1 - 0.002 18.4 0.0 0.0041 17.3 0.0 1.5 1 1 0 1 1 1 1 Fasciclin domain XPG_N PF00752.17 CCC69516.1 - 3.1e-24 85.3 0.0 7.1e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CCC69516.1 - 4.6e-19 68.6 0.0 1.2e-18 67.3 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 CCC69516.1 - 0.00035 21.1 0.0 0.0013 19.3 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Acetyltransf_16 PF05301.11 CCC69516.1 - 0.0066 16.2 0.2 0.021 14.6 0.0 1.9 2 0 0 2 2 2 1 GNAT acetyltransferase, Mec-17 HHH_2 PF12826.7 CCC69516.1 - 0.007 16.4 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif XPG_I_2 PF12813.7 CCC69516.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing NeuB PF03102.14 CCC69516.1 - 0.075 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 NeuB family Epimerase PF01370.21 CCC69517.1 - 4e-18 65.8 0.0 6.1e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCC69517.1 - 7.9e-12 44.8 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CCC69517.1 - 7.8e-10 38.3 0.0 8.6e-09 34.9 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CCC69517.1 - 1.5e-07 31.5 0.0 2.8e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CCC69517.1 - 1.7e-07 31.0 0.1 8.1e-07 28.7 0.1 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 CCC69517.1 - 6.1e-07 29.1 0.1 4.3e-05 23.0 0.1 2.9 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 CCC69517.1 - 8.2e-05 21.9 0.1 0.00031 20.0 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 CCC69517.1 - 0.00025 21.0 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 CCC69517.1 - 0.031 13.8 0.0 0.16 11.5 0.0 2.1 2 1 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 CCC69517.1 - 0.039 13.1 0.0 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short_C2 PF13561.6 CCC69517.1 - 0.086 12.4 0.0 0.23 11.0 0.0 1.7 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Ank_2 PF12796.7 CCC69518.1 - 7.4e-28 97.0 0.0 4.7e-15 56.0 0.1 2.8 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) DHHC PF01529.20 CCC69518.1 - 2.4e-23 82.7 5.7 2.4e-23 82.7 5.7 3.0 2 1 1 3 3 3 1 DHHC palmitoyltransferase Ank_4 PF13637.6 CCC69518.1 - 9.2e-22 77.1 3.6 5e-09 36.5 0.1 5.1 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCC69518.1 - 1e-20 71.6 0.1 0.00021 21.5 0.0 7.0 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 CCC69518.1 - 1.5e-20 72.6 0.2 0.00017 21.9 0.0 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 CCC69518.1 - 2.4e-20 72.3 0.3 1.1e-07 32.0 0.2 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Pex2_Pex12 PF04757.14 CCC69519.1 - 4.6e-33 114.7 6.8 7.6e-33 114.0 6.8 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 CCC69519.1 - 3.7e-08 33.6 17.2 6.8e-08 32.7 17.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCC69519.1 - 1.6e-07 31.1 16.2 2.7e-07 30.3 16.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCC69519.1 - 1.3e-06 28.1 16.4 2.9e-06 27.0 16.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCC69519.1 - 2.5e-06 27.2 15.4 5.4e-06 26.2 15.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCC69519.1 - 1.5e-05 24.7 16.2 2.9e-05 23.8 16.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CCC69519.1 - 2.1e-05 24.6 17.3 5.3e-05 23.3 17.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 CCC69519.1 - 7.2e-05 23.0 11.8 0.00017 21.8 11.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 CCC69519.1 - 8.8e-05 22.5 10.2 8.8e-05 22.5 10.2 2.4 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 CCC69519.1 - 0.0033 17.3 12.0 0.0093 15.9 12.1 1.8 1 1 0 1 1 1 1 zinc-RING finger domain U-box PF04564.15 CCC69519.1 - 0.067 13.4 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 U-box domain zf-RING_6 PF14835.6 CCC69519.1 - 0.15 11.9 10.0 0.3 11.0 10.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 CCC69519.1 - 0.18 11.9 7.1 0.32 11.1 7.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 CCC69520.1 - 2.4e-09 36.9 7.4 2.4e-09 36.9 7.4 3.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCC69520.1 - 0.0022 17.8 8.0 0.0022 17.8 8.0 3.1 4 0 0 4 4 4 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 CCC69520.1 - 0.0065 16.3 9.9 0.0065 16.3 9.9 3.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCC69520.1 - 0.019 14.9 12.1 0.019 14.9 12.1 3.6 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 CCC69521.1 - 2.6e-37 126.1 24.9 2.1e-07 31.5 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC69521.1 - 8e-11 42.1 9.0 0.028 14.7 0.0 5.8 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain SH3_9 PF14604.6 CCC69521.1 - 0.067 13.1 0.7 0.27 11.1 0.3 2.1 2 0 0 2 2 2 0 Variant SH3 domain Coatomer_WDAD PF04053.14 CCC69521.1 - 0.15 11.0 3.3 1.1 8.2 0.4 2.7 2 1 1 3 3 3 0 Coatomer WD associated region IKI3 PF04762.12 CCC69521.1 - 0.94 7.4 3.2 2.5 6.0 1.1 2.0 2 0 0 2 2 2 0 IKI3 family tRNA-synt_1b PF00579.25 CCC69522.1 - 4.5e-71 239.5 0.0 6e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) E1-E2_ATPase PF00122.20 CCC69523.1 - 7.6e-49 165.7 0.3 7.6e-49 165.7 0.3 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 CCC69523.1 - 3.3e-31 109.2 0.0 5.2e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 CCC69523.1 - 1.8e-16 60.3 2.2 1.2e-13 51.3 1.1 2.7 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 CCC69523.1 - 9.6e-05 22.2 5.5 0.00099 18.9 0.2 3.1 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase CUE PF02845.16 CCC69524.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 0 CUE domain Pmp3 PF01679.17 CCC69526.1 - 5.9e-18 64.8 7.8 6.3e-18 64.7 7.8 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BTP PF05232.12 CCC69526.1 - 0.16 12.1 3.7 0.19 11.8 3.7 1.1 1 0 0 1 1 1 0 Chlorhexidine efflux transporter DUF4191 PF13829.6 CCC69526.1 - 0.8 9.0 2.7 0.87 8.9 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) STD1 PF17235.2 CCC69527.1 - 8.4e-70 234.6 1.2 1.8e-69 233.5 1.2 1.5 1 0 0 1 1 1 1 STD1/MTH1 EVI2A PF05399.11 CCC69527.1 - 0.24 10.9 5.4 0.054 13.1 1.1 2.1 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Filament_head PF04732.14 CCC69527.1 - 2 9.3 11.8 0.82 10.6 5.3 2.3 2 0 0 2 2 2 0 Intermediate filament head (DNA binding) region Methyltransf_28 PF02636.17 CCC69528.1 - 0.00029 20.6 0.0 0.00072 19.3 0.0 1.6 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Acyltransferase PF01553.21 CCC69529.1 - 3.2e-08 33.3 0.0 2.3e-07 30.5 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase TRAPP PF04051.16 CCC69530.1 - 1.4e-32 112.4 0.0 2.1e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Dsl1_N PF11988.8 CCC69530.1 - 0.043 12.8 0.1 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal TP_methylase PF00590.20 CCC69531.1 - 3.2e-39 135.1 0.0 4.4e-39 134.6 0.0 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Sirohm_synth_M PF14824.6 CCC69531.1 - 2.7e-06 26.7 0.1 5.4e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central NAD_binding_7 PF13241.6 CCC69531.1 - 1.2e-05 25.6 0.0 3.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CCC69531.1 - 0.014 15.0 0.1 0.61 9.8 0.0 2.4 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Hydrolase_like PF13242.6 CCC69532.1 - 3.1e-27 94.5 0.0 5.3e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 CCC69532.1 - 4.7e-24 84.4 0.0 7.6e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCC69532.1 - 0.00098 19.2 0.0 0.063 13.4 0.0 2.8 2 1 1 3 3 3 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCC69532.1 - 0.057 13.7 0.0 4.1 7.6 0.0 3.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase CIAPIN1 PF05093.13 CCC69533.1 - 1.7e-37 127.9 4.6 1.7e-37 127.9 4.6 1.9 2 0 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 CCC69533.1 - 3.5e-34 117.9 0.2 5.4e-34 117.3 0.2 1.3 1 0 0 1 1 1 1 Fe-S cluster assembly protein DRE2 N-terminus Flavoprotein PF02441.19 CCC69534.1 - 2.7e-52 176.7 0.1 4.3e-52 176.0 0.1 1.3 1 0 0 1 1 1 1 Flavoprotein PIN_6 PF17146.4 CCC69535.1 - 4.8e-31 107.1 0.0 4.8e-31 107.1 0.0 2.6 3 0 0 3 3 3 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 CCC69535.1 - 1.8e-24 85.7 0.6 3.5e-24 84.7 0.6 1.5 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zinc_ribbon_9 PF14369.6 CCC69535.1 - 0.14 12.4 0.5 0.33 11.3 0.5 1.6 1 0 0 1 1 1 0 zinc-ribbon SGS PF05002.15 CCC69537.1 - 3.7e-31 107.1 1.2 3.7e-31 107.1 1.2 3.2 3 0 0 3 3 3 1 SGS domain CS PF04969.16 CCC69537.1 - 2.1e-11 44.7 0.4 5e-11 43.5 0.4 1.7 1 0 0 1 1 1 1 CS domain TPR_12 PF13424.6 CCC69537.1 - 0.12 12.7 0.1 7.1 7.0 0.1 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 CCC69537.1 - 0.17 12.4 0.4 2.9 8.5 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MAP65_ASE1 PF03999.12 CCC69538.1 - 3.2e-39 135.1 20.9 4.9e-39 134.5 20.9 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Pkinase PF00069.25 CCC69539.1 - 4.4e-57 193.4 0.0 5.2e-57 193.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69539.1 - 1.4e-16 60.6 0.0 2.2e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCC69539.1 - 3.3e-07 30.5 0.0 1.6e-06 28.2 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CCC69539.1 - 0.019 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 CCC69539.1 - 0.031 13.1 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 CCC69539.1 - 0.094 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YtxH PF12732.7 CCC69540.1 - 0.7 10.5 2.6 11 6.7 0.1 2.5 2 1 0 2 2 2 0 YtxH-like protein Ribosomal_L3 PF00297.22 CCC69541.1 - 1.3e-190 633.1 12.6 1.5e-190 632.9 12.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 Tho1_MOS11_C PF18592.1 CCC69541.1 - 1.1 9.1 3.1 2 8.3 0.4 2.5 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain Trp_syntA PF00290.20 CCC69542.1 - 6.8e-98 326.6 0.4 1.1e-97 326.0 0.4 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.25 CCC69542.1 - 8.7e-48 163.2 3.2 8.9e-48 163.2 1.6 1.8 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme BtpA PF03437.15 CCC69542.1 - 0.017 14.5 0.6 0.052 13.0 0.1 2.0 2 0 0 2 2 2 0 BtpA family HMGL-like PF00682.19 CCC69542.1 - 0.086 12.4 0.1 29 4.1 0.0 3.5 3 0 0 3 3 3 0 HMGL-like PcrB PF01884.17 CCC69542.1 - 0.17 11.3 0.3 0.95 8.9 0.1 2.2 3 0 0 3 3 3 0 PcrB family Rrn6 PF10214.9 CCC69543.1 - 4.3e-109 366.3 20.0 5e-108 362.8 20.0 1.9 1 1 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Cbl_N2 PF02761.14 CCC69543.1 - 0.36 11.6 2.2 24 5.7 0.1 2.7 1 1 1 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain Cgr1 PF03879.14 CCC69544.1 - 5.4e-33 113.6 37.9 6.1e-33 113.4 37.9 1.0 1 0 0 1 1 1 1 Cgr1 family DUF2048 PF09752.9 CCC69544.1 - 0.013 14.6 3.9 0.014 14.5 3.9 1.1 1 0 0 1 1 1 0 Abhydrolase domain containing 18 UPF0242 PF06785.11 CCC69544.1 - 7.6 6.6 17.8 9.4 6.3 17.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PPR_2 PF13041.6 CCC69545.1 - 3.6e-15 55.9 1.3 3.1e-09 36.9 0.0 4.2 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.6 CCC69545.1 - 3.9e-09 36.4 10.9 2.3e-06 27.6 0.1 3.8 3 0 0 3 3 3 2 Pentatricopeptide repeat domain PPR_long PF17177.4 CCC69545.1 - 0.00025 20.5 0.0 0.004 16.6 0.0 2.4 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 CCC69545.1 - 0.00063 19.8 0.0 0.2 11.9 0.0 3.2 2 0 0 2 2 2 1 PPR repeat PPR_1 PF12854.7 CCC69545.1 - 0.011 15.4 0.2 12 5.7 0.0 3.7 4 0 0 4 4 4 0 PPR repeat DUF2838 PF10998.8 CCC69546.1 - 4.3e-41 139.6 15.5 4.3e-41 139.6 15.5 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF2838) Phage_GP20 PF06810.11 CCC69546.1 - 0.078 12.8 4.6 0.56 10.0 0.1 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 NPV_P10 PF05531.12 CCC69546.1 - 0.11 13.0 5.9 0.4 11.2 0.1 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ribosomal_L24e PF01246.20 CCC69547.1 - 2.2e-29 101.5 0.2 2.2e-29 101.5 0.2 2.1 2 1 0 2 2 2 1 Ribosomal protein L24e UNC-79 PF14776.6 CCC69547.1 - 0.2 10.4 1.0 0.24 10.1 1.0 1.0 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 DUF1279 PF06916.13 CCC69548.1 - 2.1e-27 95.5 0.1 3.3e-27 94.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) V-SNARE_C PF12352.8 CCC69549.1 - 0.16 12.2 7.0 1.1 9.5 0.1 3.7 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus RT_RNaseH_2 PF17919.1 CCC69550.1 - 1.3e-18 66.9 0.1 4e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCC69550.1 - 6.2e-18 65.0 0.0 1.4e-17 63.9 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase 5_3_exonuc_N PF02739.16 CCC69550.1 - 0.013 15.4 0.0 0.037 13.9 0.0 1.7 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain RVT_3 PF13456.6 CCC69550.1 - 0.03 14.1 0.0 0.12 12.2 0.0 2.1 2 1 0 2 2 2 0 Reverse transcriptase-like DUF2428 PF10350.9 CCC69551.1 - 1.1e-43 149.6 0.0 2.4e-43 148.4 0.0 1.6 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 CCC69551.1 - 0.016 15.4 0.1 0.19 12.1 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat Cnd1 PF12717.7 CCC69551.1 - 0.3 11.1 10.8 0.094 12.8 0.8 4.2 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 PALP PF00291.25 CCC69552.1 - 9.9e-62 209.0 0.0 1.2e-61 208.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 CCC69552.1 - 3.9e-16 59.2 0.0 2.1e-08 34.5 0.1 2.7 2 0 0 2 2 2 2 CBS domain GHMP_kinases_C PF08544.13 CCC69552.1 - 0.088 13.2 0.1 2.5 8.5 0.0 2.8 3 0 0 3 3 3 0 GHMP kinases C terminal Enolase_C PF00113.22 CCC69553.1 - 7.3e-141 468.6 0.0 1e-140 468.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CCC69553.1 - 8.3e-56 187.8 0.1 1.3e-55 187.1 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CCC69553.1 - 4.2e-07 29.7 0.0 6.6e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CCC69553.1 - 0.0001 21.5 0.0 0.00024 20.4 0.0 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus CSTF2_hinge PF14327.6 CCC69554.1 - 6.2e-25 87.5 0.8 6.2e-25 87.5 0.8 3.4 4 0 0 4 4 4 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 CCC69554.1 - 5.1e-07 29.2 3.0 1.3e-06 27.9 3.0 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal PEMT PF04191.13 CCC69555.1 - 2.7e-59 198.1 19.4 4.5e-35 120.2 1.2 3.6 4 0 0 4 4 4 2 Phospholipid methyltransferase SKICH PF17751.1 CCC69555.1 - 0.025 15.1 0.1 0.079 13.5 0.1 1.9 1 0 0 1 1 1 0 SKICH domain Spt4 PF06093.13 CCC69556.1 - 0.023 14.8 0.9 4 7.6 0.0 3.0 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger FXMRP1_C_core PF12235.8 CCC69557.1 - 2.5e-05 24.9 0.2 4e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 Fragile X-related 1 protein core C terminal DUF2046 PF09755.9 CCC69557.1 - 0.0007 18.9 3.7 0.00082 18.7 3.7 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein H4 (DUF2046) LURAP PF14854.6 CCC69557.1 - 0.0029 17.5 0.5 0.0043 17.0 0.5 1.3 1 0 0 1 1 1 1 Leucine rich adaptor protein Prp19 PF08606.11 CCC69557.1 - 0.062 13.3 2.7 0.18 11.8 2.7 1.8 1 1 0 1 1 1 0 Prp19/Pso4-like G_glu_transpept PF01019.21 CCC69557.1 - 0.091 11.5 0.0 0.097 11.4 0.0 1.0 1 0 0 1 1 1 0 Gamma-glutamyltranspeptidase APC_N_CC PF16689.5 CCC69557.1 - 0.097 12.8 5.6 0.16 12.0 4.3 2.1 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain Pet20 PF08692.10 CCC69557.1 - 0.23 12.2 2.0 0.36 11.5 1.9 1.6 1 1 0 1 1 1 0 Mitochondrial protein Pet20 FAM76 PF16046.5 CCC69557.1 - 0.38 10.0 5.7 0.46 9.8 5.7 1.1 1 0 0 1 1 1 0 FAM76 protein YabA PF06156.13 CCC69557.1 - 1.7 9.4 6.2 3.3 8.4 6.3 1.6 1 1 0 1 1 1 0 Initiation control protein YabA Glyco_tran_28_C PF04101.16 CCC69558.1 - 7.6e-27 94.3 0.0 3.5e-26 92.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Cmc1 PF08583.10 CCC69558.1 - 0.061 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like MIF4G PF02854.19 CCC69559.1 - 3.1e-51 174.0 0.1 4.8e-51 173.4 0.1 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.8 CCC69559.1 - 4.5e-26 90.8 0.4 2.8e-25 88.3 0.4 2.5 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 DUF1484 PF07363.11 CCC69559.1 - 1.2 10.2 0.0 1.2 10.2 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1484) Gtr1_RagA PF04670.12 CCC69560.1 - 4e-55 186.7 1.0 5.1e-55 186.3 1.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RasGEF PF00617.19 CCC69561.1 - 4.5e-55 186.6 0.7 4.5e-55 186.6 0.7 3.1 4 0 0 4 4 4 1 RasGEF domain RasGEF_N PF00618.20 CCC69561.1 - 7.2e-20 71.2 0.1 7.2e-20 71.2 0.1 3.5 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.28 CCC69561.1 - 2.1e-10 40.0 0.2 5.4e-10 38.7 0.2 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCC69561.1 - 2.7e-09 36.8 0.0 6.1e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCC69561.1 - 2.3e-07 30.4 0.0 4.8e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF1944 PF09175.10 CCC69561.1 - 0.1 12.5 0.0 0.33 10.8 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1944) DUF4719 PF15843.5 CCC69561.1 - 0.14 12.3 1.4 0.35 10.9 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) Ribonucleas_3_3 PF14622.6 CCC69563.1 - 3.3e-20 72.6 0.0 4.3e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 CCC69563.1 - 0.0013 19.3 0.0 0.0041 17.7 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain MA3 PF02847.17 CCC69563.1 - 0.14 12.2 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 MA3 domain GIT_SHD PF08518.11 CCC69564.1 - 8.5e-22 76.5 0.9 1.2e-09 37.6 0.2 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT GIT1_C PF12205.8 CCC69564.1 - 0.053 13.6 0.3 0.053 13.6 0.3 2.8 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term YabA PF06156.13 CCC69564.1 - 0.054 14.1 0.4 0.054 14.1 0.4 3.8 4 1 0 4 4 4 0 Initiation control protein YabA Septin PF00735.18 CCC69565.1 - 1.5e-106 355.8 4.2 1.5e-106 355.8 4.2 2.0 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.27 CCC69565.1 - 1.3e-05 24.8 0.5 1.3e-05 24.8 0.5 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 CCC69565.1 - 0.0001 22.5 0.3 0.00048 20.3 0.3 2.3 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CCC69565.1 - 0.00021 21.4 1.7 0.00021 21.4 1.7 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 CCC69565.1 - 0.00026 21.4 0.1 0.0028 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 CCC69565.1 - 0.00071 19.3 0.0 0.0014 18.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CCC69565.1 - 0.0019 18.5 1.1 0.0082 16.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCC69565.1 - 0.0041 17.0 1.3 0.0041 17.0 1.3 2.8 3 1 0 3 3 3 1 RsgA GTPase Ras PF00071.22 CCC69565.1 - 0.0046 16.6 0.4 0.054 13.1 0.0 2.6 1 1 1 2 2 2 1 Ras family ABC_tran PF00005.27 CCC69565.1 - 0.041 14.4 0.1 0.041 14.4 0.1 2.7 3 0 0 3 3 2 0 ABC transporter AAA_7 PF12775.7 CCC69565.1 - 0.048 13.2 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 CCC69565.1 - 0.12 12.1 4.2 0.19 11.4 0.1 2.7 3 0 0 3 3 3 0 AAA domain Exonuc_VII_L PF02601.15 CCC69565.1 - 0.3 10.6 11.5 0.51 9.9 11.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3987 PF13148.6 CCC69565.1 - 0.43 9.5 3.8 9.5 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) FAM76 PF16046.5 CCC69565.1 - 0.88 8.9 12.8 1.8 7.9 12.8 1.5 1 0 0 1 1 1 0 FAM76 protein Dynamin_N PF00350.23 CCC69565.1 - 2.6 8.1 15.0 0.75 9.8 2.4 3.5 2 2 0 2 2 2 0 Dynamin family DUF1090 PF06476.12 CCC69565.1 - 7.3 6.7 21.1 2.3 8.4 13.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) HSP70 PF00012.20 CCC69566.1 - 9.3e-262 869.5 7.5 1.1e-261 869.4 7.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCC69566.1 - 1.3e-17 63.6 0.0 2.3e-16 59.5 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CCC69566.1 - 0.0021 17.8 0.0 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CCC69566.1 - 0.019 14.0 0.3 0.13 11.2 0.1 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.6 CCC69566.1 - 0.032 14.6 1.7 20 5.6 0.0 3.7 3 2 0 3 3 3 0 Cell division protein FtsA Hydantoinase_A PF01968.18 CCC69566.1 - 0.12 11.6 0.1 0.12 11.6 0.1 2.0 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase TMCO5 PF14992.6 CCC69566.1 - 1.7 8.1 7.3 3.2 7.3 7.3 1.3 1 0 0 1 1 1 0 TMCO5 family NPR3 PF03666.13 CCC69567.1 - 1.9e-166 554.5 12.2 1.9e-166 554.5 12.2 1.8 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 MFS_1 PF07690.16 CCC69568.1 - 2.3e-40 138.6 32.6 2.3e-40 138.6 32.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC69568.1 - 1e-09 37.8 13.0 1e-09 37.8 13.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CCC69568.1 - 4.4e-09 35.3 7.2 7.1e-09 34.6 7.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.6 CCC69568.1 - 0.061 13.0 0.4 0.061 13.0 0.4 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) DUF4191 PF13829.6 CCC69568.1 - 3.7 6.8 6.4 0.31 10.4 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Creatinase_N_2 PF16189.5 CCC69569.1 - 2.4e-42 144.8 0.9 1.1e-41 142.6 0.2 2.3 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 CCC69569.1 - 5.8e-42 143.8 0.0 8.5e-42 143.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Peptidase_M24_C PF16188.5 CCC69569.1 - 3.7e-21 75.0 3.1 8e-21 73.9 2.2 2.2 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 CCC69569.1 - 1.3e-07 32.3 0.0 3.9e-07 30.8 0.0 1.8 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain AIP3 PF03915.13 CCC69569.1 - 0.0076 15.4 4.0 0.018 14.1 0.5 2.4 2 1 0 2 2 2 1 Actin interacting protein 3 TDH PF03347.13 CCC69569.1 - 0.008 15.8 0.2 0.018 14.6 0.2 1.5 1 0 0 1 1 1 1 Vibrio thermostable direct hemolysin Glyco_hydro_49 PF03718.13 CCC69569.1 - 0.17 11.9 1.5 8.1 6.5 0.0 2.8 3 0 0 3 3 3 0 Glycosyl hydrolase family 49 Phosphodiest PF01663.22 CCC69570.1 - 1.2e-12 48.2 0.4 1.7e-12 47.6 0.4 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 CCC69570.1 - 0.0033 16.8 1.9 0.0033 16.8 1.9 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily Sulfatase PF00884.23 CCC69570.1 - 0.11 11.9 0.1 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Sulfatase WDCP PF15390.6 CCC69571.1 - 2 6.7 18.8 0.14 10.5 13.1 1.8 2 0 0 2 2 2 0 WD repeat and coiled-coil-containing protein family zf-C2H2 PF00096.26 CCC69572.1 - 2.1e-06 27.8 25.4 1.5e-05 25.1 3.3 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC69572.1 - 0.00033 21.0 11.5 0.0017 18.7 4.6 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC69572.1 - 0.00083 20.0 2.3 0.00083 20.0 2.3 3.6 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCC69572.1 - 0.0059 16.6 1.8 0.019 15.0 1.8 1.9 1 0 0 1 1 1 1 C2H2-type zinc finger MPP6 PF10175.9 CCC69572.1 - 0.0074 16.8 3.2 0.028 14.9 0.1 2.6 2 0 0 2 2 2 1 M-phase phosphoprotein 6 TFIIA PF03153.13 CCC69572.1 - 0.035 14.1 38.1 0.025 14.6 16.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_8 PF15909.5 CCC69572.1 - 0.046 14.0 5.8 0.16 12.2 5.8 2.0 1 0 0 1 1 1 0 C2H2-type zinc ribbon U-box PF04564.15 CCC69572.1 - 0.11 12.7 1.8 22 5.3 0.1 3.3 3 0 0 3 3 3 0 U-box domain RabGAP-TBC PF00566.18 CCC69573.1 - 0.0053 16.4 21.2 0.0068 16.1 0.2 4.2 4 1 0 4 4 4 2 Rab-GTPase-TBC domain ENTH PF01417.20 CCC69574.1 - 4.2e-33 114.0 0.9 6.3e-33 113.5 0.9 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 CCC69574.1 - 0.00026 20.1 0.1 0.00048 19.2 0.1 1.4 1 1 0 1 1 1 1 ANTH domain VHS PF00790.19 CCC69574.1 - 0.014 15.3 0.1 0.023 14.6 0.1 1.4 1 0 0 1 1 1 0 VHS domain ubiquitin PF00240.23 CCC69575.1 - 5.3e-168 545.1 27.6 4.9e-33 112.7 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 CCC69575.1 - 4.9e-79 260.2 28.3 3e-15 55.8 0.7 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCC69575.1 - 8.6e-28 96.6 14.7 0.00063 20.2 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 CCC69575.1 - 6e-20 71.0 5.5 0.039 13.9 0.0 5.2 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 CCC69575.1 - 4.5e-18 65.4 12.4 0.043 14.2 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCC69575.1 - 3.1e-17 62.7 5.2 0.15 12.2 0.0 6.0 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CCC69575.1 - 1.2e-15 57.9 3.6 0.31 11.6 0.2 5.2 1 1 3 5 5 5 5 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 CCC69575.1 - 3e-08 33.3 1.3 2.7 7.3 0.0 4.3 4 0 0 4 4 4 4 RNA methyltransferase Ubiquitin_4 PF18036.1 CCC69575.1 - 1.2e-07 31.6 32.0 23 5.1 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain DUF2870 PF11069.8 CCC69575.1 - 2.5e-07 31.0 0.0 40 4.7 0.0 5.6 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) DUF3861 PF12977.7 CCC69575.1 - 5.8e-07 29.6 5.3 19 5.5 0.0 5.3 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) ACT_5 PF13710.6 CCC69575.1 - 1.8e-06 27.7 7.7 14 5.6 0.0 5.3 5 0 0 5 5 5 0 ACT domain Big_7 PF17957.1 CCC69575.1 - 2.7e-06 28.0 0.6 73 4.2 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig domain DUF969 PF06149.12 CCC69575.1 - 8.5e-06 25.3 0.0 33 3.8 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF969) UDP-g_GGTase PF06427.11 CCC69575.1 - 1.5e-05 25.0 7.4 10 6.3 0.0 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase ORF11CD3 PF10549.9 CCC69575.1 - 4.7e-05 23.4 0.0 64 3.8 0.0 5.4 5 0 0 5 5 5 0 ORF11CD3 domain DUF493 PF04359.14 CCC69575.1 - 0.00041 20.9 0.1 1.9e+02 2.7 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF493) YcgR_2 PF12945.7 CCC69575.1 - 0.00045 20.3 9.7 39 4.5 0.1 5.2 5 0 0 5 5 5 0 Flagellar protein YcgR ACT_4 PF13291.6 CCC69575.1 - 0.002 18.7 2.5 1.9e+02 2.7 0.0 5.1 5 0 0 5 5 5 0 ACT domain Baculo_p48 PF04878.13 CCC69575.1 - 0.026 13.5 0.0 87 1.9 0.0 3.8 4 0 0 4 4 4 0 Baculovirus P48 protein ProRS-C_2 PF09181.10 CCC69575.1 - 0.16 12.2 9.2 1.4e+02 2.7 0.1 5.0 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Tash_PEST PF07708.11 CCC69575.1 - 0.21 11.8 36.0 8.2 6.7 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif HAMP_N3 PF18575.1 CCC69575.1 - 0.25 11.0 3.3 2.6e+02 1.3 0.0 4.7 5 0 0 5 5 5 0 HAMP N-terminal domain 3 Myosin_N PF02736.19 CCC69575.1 - 0.32 10.9 9.4 1.5e+02 2.4 0.0 6.1 5 0 0 5 5 5 0 Myosin N-terminal SH3-like domain PI3K_p85B PF02192.16 CCC69575.1 - 6.2 6.6 13.6 1.3e+02 2.4 0.1 5.1 5 0 0 5 5 5 0 PI3-kinase family, p85-binding domain Ecm29 PF13001.7 CCC69576.1 - 1.2e-152 509.2 3.8 1.2e-152 509.2 3.8 2.2 3 0 0 3 3 3 1 Proteasome stabiliser HEAT PF02985.22 CCC69576.1 - 6.8e-12 44.6 15.5 0.074 13.3 0.0 9.8 11 0 0 11 11 11 4 HEAT repeat Vac14_Fab1_bd PF12755.7 CCC69576.1 - 1.3e-07 32.1 0.5 0.022 15.3 0.0 6.3 6 0 0 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 CCC69576.1 - 8.8e-06 26.0 0.2 50 4.4 0.0 7.2 6 1 0 6 6 6 0 HEAT repeats HEAT_EZ PF13513.6 CCC69576.1 - 5.9e-05 23.5 0.4 30 5.2 0.0 6.1 6 1 1 7 7 7 1 HEAT-like repeat Fer2_3 PF13085.6 CCC69577.1 - 1.5e-34 118.2 0.1 2.7e-34 117.4 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 CCC69577.1 - 2.7e-09 37.4 7.8 2.7e-09 37.4 7.8 2.2 2 1 1 3 3 3 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 CCC69577.1 - 3.2e-08 33.9 7.9 3.2e-08 33.9 7.9 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 CCC69577.1 - 2e-07 31.0 4.3 2e-07 31.0 4.3 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 CCC69577.1 - 0.0016 19.0 6.0 0.0016 19.0 6.0 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.6 CCC69577.1 - 0.0075 16.4 0.5 0.57 10.4 0.1 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 CCC69577.1 - 0.0078 16.1 1.2 0.0078 16.1 1.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 CCC69577.1 - 0.014 15.6 7.9 0.014 15.6 7.9 2.5 2 1 0 2 2 2 0 4Fe-4S dicluster domain V-SNARE_C PF12352.8 CCC69578.1 - 3e-15 56.3 6.1 3e-15 56.3 6.1 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Syntaxin-6_N PF09177.11 CCC69578.1 - 0.0024 18.4 3.7 0.0024 18.4 3.7 2.4 1 1 1 2 2 2 1 Syntaxin 6, N-terminal DUF349 PF03993.12 CCC69578.1 - 0.0071 16.6 0.2 0.018 15.3 0.2 1.8 1 0 0 1 1 1 1 Domain of Unknown Function (DUF349) RseA_N PF03872.13 CCC69578.1 - 0.025 15.1 1.8 0.041 14.4 1.1 1.8 1 1 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain Musclin PF11037.8 CCC69578.1 - 0.053 13.4 2.7 0.05 13.5 1.3 1.7 2 1 0 2 2 2 0 Insulin-resistance promoting peptide in skeletal muscle ETRAMP PF09716.10 CCC69578.1 - 0.15 12.1 6.3 3.8 7.7 3.0 3.1 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF724 PF05266.14 CCC69578.1 - 2.6 7.8 14.1 1.9 8.3 7.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Occludin_ELL PF07303.13 CCC69578.1 - 5.5 7.8 9.3 3.3 8.5 3.2 2.7 2 1 1 3 3 3 0 Occludin homology domain Sec20 PF03908.13 CCC69578.1 - 7.1 6.6 11.5 0.31 11.0 1.2 2.9 1 1 1 3 3 3 0 Sec20 MIP PF00230.20 CCC69579.1 - 6.7e-63 212.4 5.5 9.3e-63 212.0 5.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.16 CCC69580.1 - 1.9e-69 233.4 0.2 8.6e-69 231.2 0.1 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.21 CCC69580.1 - 1.2e-48 165.8 0.0 1.2e-40 139.6 0.0 2.7 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Ribosomal_L7Ae PF01248.26 CCC69581.1 - 1.9e-23 82.0 0.6 3.1e-23 81.3 0.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.22 CCC69582.1 - 9.8e-18 63.7 1.1 1.7e-08 34.1 0.1 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC69582.1 - 0.00023 21.2 0.0 0.042 14.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif RRM_Rrp7 PF17799.1 CCC69582.1 - 0.053 13.3 0.1 2.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Rrp7 RRM-like N-terminal domain FoP_duplication PF13865.6 CCC69582.1 - 0.67 10.5 7.8 1.2 9.7 7.1 1.8 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 ABC_tran PF00005.27 CCC69583.1 - 7.6e-56 188.4 0.1 4.3e-32 111.5 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 CCC69583.1 - 3e-55 187.8 30.3 9.6e-36 123.8 9.6 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 CCC69583.1 - 4.2e-10 39.4 3.3 2.7e-05 23.7 1.9 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCC69583.1 - 6.8e-10 39.8 4.4 0.00029 21.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 CCC69583.1 - 2.2e-08 34.3 1.2 0.0084 16.0 0.0 3.8 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCC69583.1 - 1.9e-07 30.7 0.1 0.0049 16.6 0.0 3.2 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCC69583.1 - 2.8e-06 27.4 0.0 0.0083 16.1 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CCC69583.1 - 4.6e-05 23.5 0.4 0.032 14.3 0.1 3.1 3 0 0 3 3 2 1 50S ribosome-binding GTPase T2SSE PF00437.20 CCC69583.1 - 5.9e-05 22.3 0.1 0.12 11.4 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_22 PF13401.6 CCC69583.1 - 0.0001 22.6 0.1 1.1 9.6 0.1 3.2 2 1 0 2 2 2 2 AAA domain AAA_24 PF13479.6 CCC69583.1 - 0.00011 22.0 0.4 0.017 14.8 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCC69583.1 - 0.00046 20.6 0.0 1.7 9.0 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.6 CCC69583.1 - 0.00046 20.0 11.9 0.035 13.8 1.7 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_14 PF13173.6 CCC69583.1 - 0.001 19.1 1.4 14 5.8 0.3 4.1 4 0 0 4 4 3 0 AAA domain ATP_bind_1 PF03029.17 CCC69583.1 - 0.0022 17.8 0.0 23 4.7 0.0 3.8 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_25 PF13481.6 CCC69583.1 - 0.0037 16.9 0.0 0.13 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CCC69583.1 - 0.007 16.8 1.0 7.3 7.0 0.0 3.4 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CCC69583.1 - 0.0071 15.9 0.0 1 8.9 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Dynamin_N PF00350.23 CCC69583.1 - 0.0082 16.2 3.6 0.21 11.6 0.1 3.1 3 0 0 3 3 2 1 Dynamin family Zeta_toxin PF06414.12 CCC69583.1 - 0.011 15.0 0.0 0.91 8.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 CCC69583.1 - 0.013 15.2 0.0 4.5 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CCC69583.1 - 0.02 15.0 5.2 0.79 9.8 0.0 2.9 3 0 0 3 3 2 0 Helicase HerA, central domain Adeno_IVa2 PF02456.15 CCC69583.1 - 0.02 13.7 0.0 0.18 10.6 0.0 2.3 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATPase_2 PF01637.18 CCC69583.1 - 0.025 14.5 0.9 1.7 8.5 0.0 3.3 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea 30K_MP_core PF17644.1 CCC69583.1 - 0.034 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Core domain of 30K viral movement proteins Sigma54_activat PF00158.26 CCC69583.1 - 0.045 13.4 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Roc PF08477.13 CCC69583.1 - 0.052 13.8 0.1 15 5.9 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 CCC69583.1 - 0.054 13.1 2.4 0.76 9.3 0.1 2.7 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 CCC69583.1 - 0.063 13.0 0.7 9.7 5.9 0.0 2.9 3 0 0 3 3 3 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 CCC69583.1 - 0.069 12.5 0.0 6.5 6.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 CCC69583.1 - 0.11 11.4 0.0 14 4.4 0.0 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ResIII PF04851.15 CCC69583.1 - 0.15 12.0 0.4 13 5.7 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AA_permease_2 PF13520.6 CCC69584.1 - 5.1e-62 210.1 40.3 6.4e-62 209.8 40.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCC69584.1 - 6.9e-12 44.7 41.1 9.3e-12 44.3 41.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2621 PF11084.8 CCC69584.1 - 0.38 10.7 6.6 2.8 7.9 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) Cofilin_ADF PF00241.20 CCC69586.1 - 2.8e-41 140.1 0.2 3.1e-41 140.0 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DpnII-MboI PF18742.1 CCC69586.1 - 0.086 12.5 0.4 0.13 11.9 0.4 1.3 1 1 0 1 1 1 0 REase_DpnII-MboI SET PF00856.28 CCC69587.1 - 5.8e-08 33.3 0.0 1.3e-07 32.2 0.0 1.7 1 1 0 1 1 1 1 SET domain Epimerase PF01370.21 CCC69588.1 - 2.8e-13 49.9 0.0 4e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCC69588.1 - 5.8e-09 35.4 0.0 8.7e-09 34.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CCC69588.1 - 5.6e-06 25.7 0.0 3.5e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CCC69588.1 - 0.00014 21.4 0.0 1 8.8 0.0 3.0 3 0 0 3 3 3 2 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 CCC69588.1 - 0.00028 20.4 0.1 0.00052 19.5 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase CCM2_C PF16545.5 CCC69588.1 - 0.15 12.6 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology LpxB PF02684.15 CCC69589.1 - 0.12 11.1 0.1 0.16 10.8 0.1 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase Sir1 PF11603.8 CCC69590.1 - 1.5e-36 125.5 0.1 2.7e-36 124.7 0.1 1.4 1 0 0 1 1 1 1 Regulatory protein Sir1 DUF4897 PF16238.5 CCC69591.1 - 0.14 12.0 0.4 0.35 10.7 0.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4897) Sir1 PF11603.8 CCC69592.1 - 0.0049 17.3 0.1 0.085 13.3 0.0 2.2 2 0 0 2 2 2 1 Regulatory protein Sir1 Pex2_Pex12 PF04757.14 CCC69593.1 - 1.2e-13 51.2 7.9 2.5e-13 50.2 7.9 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CCC69593.1 - 0.00028 20.7 14.8 0.00049 19.9 14.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RhoGAP PF00620.27 CCC69594.1 - 5.3e-38 130.2 0.9 5.3e-38 130.2 0.9 2.5 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.22 CCC69594.1 - 1.4e-29 102.1 49.1 7.8e-12 45.2 5.7 4.5 4 0 0 4 4 4 4 LIM domain DUF1487 PF07368.11 CCC69594.1 - 0.15 11.4 2.6 0.13 11.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) zf-ribbon_3 PF13248.6 CCC69594.1 - 2 7.9 7.8 9.7 5.8 0.1 3.6 4 0 0 4 4 4 0 zinc-ribbon domain SID PF11778.8 CCC69595.1 - 1.6e-50 170.7 8.6 1.6e-50 170.7 8.6 2.6 3 0 0 3 3 3 1 Septation initiation Tup_N PF08581.10 CCC69595.1 - 0.15 12.4 0.1 0.15 12.4 0.1 6.4 3 1 3 6 6 6 0 Tup N-terminal DUF4618 PF15397.6 CCC69595.1 - 2.3 7.6 49.0 2.3 7.6 24.5 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) DUF5082 PF16888.5 CCC69595.1 - 3 8.1 42.3 3.4 7.9 11.8 4.4 1 1 3 4 4 4 0 Domain of unknown function (DUF5082) Amidohydro_1 PF01979.20 CCC69596.1 - 1.4e-77 261.4 0.0 1.6e-77 261.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CCC69596.1 - 2.5e-05 23.9 0.0 0.0036 16.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Hydrolase_6 PF13344.6 CCC69598.1 - 1.1e-27 96.1 0.0 2.1e-27 95.2 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCC69598.1 - 6.3e-13 49.5 0.0 3.5e-12 47.0 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCC69598.1 - 1.9e-12 47.1 0.0 3.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 CCC69598.1 - 6.2e-08 32.9 0.0 0.001 19.2 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF5091 PF17012.5 CCC69598.1 - 0.15 12.4 0.1 16 5.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5091) PEPCK_GTP PF00821.18 CCC69598.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain Hpt PF01627.23 CCC69599.1 - 5.1e-11 42.7 0.1 8.1e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Hpt domain RabGAP-TBC PF00566.18 CCC69600.1 - 1.9e-30 106.1 18.9 5.2e-29 101.4 10.3 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain SLM4 PF16818.5 CCC69600.1 - 0.081 12.9 0.7 0.28 11.2 0.7 1.9 1 0 0 1 1 1 0 Protein SLM4 PAPA-1 PF04795.12 CCC69601.1 - 8.7e-19 68.1 6.8 8.7e-19 68.1 6.8 2.9 3 0 0 3 3 3 1 PAPA-1-like conserved region SDA1 PF05285.12 CCC69601.1 - 0.82 9.0 44.1 1.3 8.4 44.1 1.2 1 0 0 1 1 1 0 SDA1 LIM_bind PF01803.16 CCC69602.1 - 3.1e-64 216.8 1.3 3.1e-64 216.8 1.3 2.5 3 0 0 3 3 3 1 LIM-domain binding protein Desmo_N PF06771.11 CCC69602.1 - 0.0025 18.1 0.0 0.0075 16.6 0.0 1.8 1 0 0 1 1 1 1 Viral Desmoplakin N-terminus FUSC_2 PF13515.6 CCC69603.1 - 5.8e-09 36.2 22.8 3.8e-07 30.3 6.5 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 CCC69603.1 - 5.9e-06 25.6 3.8 5.9e-06 25.6 3.8 2.9 2 1 1 3 3 3 1 Putative ER transporter, 6TM, N-terminal ALMT PF11744.8 CCC69603.1 - 4.7e-05 22.4 3.8 0.00016 20.6 0.1 2.7 3 0 0 3 3 3 1 Aluminium activated malate transporter ArAE_2 PF10334.9 CCC69603.1 - 0.0001 22.3 0.1 0.00022 21.2 0.1 1.5 1 0 0 1 1 1 1 Aromatic acid exporter family member 2 DNA_pol_E_B PF04042.16 CCC69603.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Y_phosphatase PF00102.27 CCC69604.1 - 2.9e-54 184.1 1.0 8.8e-54 182.5 1.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 CCC69604.1 - 0.00012 21.9 0.0 0.00031 20.5 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 CCC69604.1 - 0.019 14.9 0.0 0.059 13.3 0.0 1.7 1 1 0 1 1 1 0 Tyrosine phosphatase family HSP70 PF00012.20 CCC69605.1 - 1.1e-228 760.3 7.3 1.3e-228 760.1 7.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCC69605.1 - 1.5e-16 60.1 0.2 6.1e-15 54.9 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CCC69605.1 - 0.0013 18.5 0.0 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CCC69605.1 - 0.003 17.9 4.7 1.5 9.2 0.1 3.8 3 2 0 3 3 3 2 Cell division protein FtsA DUF1539 PF07560.11 CCC69605.1 - 0.18 11.9 0.3 9.9 6.3 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) Hom_end_hint PF05203.16 CCC69606.1 - 1.5e-45 155.9 0.0 1.9e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.14 CCC69606.1 - 5.2e-41 139.2 0.0 5.7e-34 116.6 0.0 2.5 2 0 0 2 2 2 2 Homing endonuclease LAGLIDADG_3 PF14528.6 CCC69606.1 - 1.2e-08 35.1 0.0 3.8e-05 23.9 0.0 2.6 2 0 0 2 2 2 2 LAGLIDADG-like domain DUF1794 PF08768.11 CCC69606.1 - 0.19 11.6 0.4 1.7 8.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1794) ArfGap PF01412.18 CCC69607.1 - 5.9e-33 113.4 0.0 2.4e-32 111.5 0.0 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf HSBP1 PF06825.12 CCC69608.1 - 0.092 12.6 2.5 0.55 10.1 0.0 3.3 4 0 0 4 4 4 0 Heat shock factor binding protein 1 PKcGMP_CC PF16808.5 CCC69608.1 - 1.7 8.5 7.3 0.11 12.3 2.0 1.8 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Septin PF00735.18 CCC69609.1 - 6.5e-74 248.7 7.3 7.7e-68 228.8 0.4 2.9 3 0 0 3 3 3 2 Septin AAA_24 PF13479.6 CCC69609.1 - 0.0022 17.7 0.2 0.027 14.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 CCC69609.1 - 0.0032 17.8 0.2 0.012 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCC69609.1 - 0.0056 17.2 3.6 0.0076 16.8 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CCC69609.1 - 0.0066 16.6 0.1 0.034 14.3 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 CCC69609.1 - 0.011 15.6 0.0 0.87 9.5 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase AAA PF00004.29 CCC69609.1 - 0.037 14.4 0.2 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 CCC69609.1 - 0.037 13.5 0.0 0.071 12.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AIG1 PF04548.16 CCC69609.1 - 0.04 13.2 2.8 0.065 12.6 0.0 2.3 2 0 0 2 2 2 0 AIG1 family Dynamin_N PF00350.23 CCC69609.1 - 0.055 13.5 0.0 0.055 13.5 0.0 3.5 3 1 0 3 3 2 0 Dynamin family AAA_16 PF13191.6 CCC69609.1 - 0.056 13.8 2.7 0.22 11.9 0.0 2.9 3 1 0 3 3 3 0 AAA ATPase domain Mg_chelatase PF01078.21 CCC69609.1 - 0.083 12.3 0.2 0.36 10.2 0.0 2.1 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 CCC69609.1 - 0.12 12.7 0.1 0.5 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase GTP_EFTU PF00009.27 CCC69609.1 - 0.42 10.1 0.0 0.42 10.1 0.0 3.1 3 2 0 3 3 3 0 Elongation factor Tu GTP binding domain DUF4611 PF15387.6 CCC69609.1 - 0.83 9.9 5.9 0.12 12.6 0.8 2.2 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) DUF3835 PF12927.7 CCC69609.1 - 3.3 8.6 7.7 2.7 8.9 1.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) Synaptobrevin PF00957.21 CCC69609.1 - 3.9 7.3 7.4 0.28 11.0 1.5 2.2 2 0 0 2 2 2 0 Synaptobrevin RRM_1 PF00076.22 CCC69610.1 - 2.6e-18 65.6 0.0 2.1e-16 59.5 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SUR7 PF06687.12 CCC69612.1 - 1.2e-42 146.0 13.0 1.4e-42 145.7 13.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 CCC69612.1 - 0.0021 18.0 7.0 0.004 17.1 7.0 1.5 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 CrgA PF06781.12 CCC69612.1 - 0.035 14.2 0.9 0.035 14.2 0.9 2.5 3 1 1 4 4 4 0 Cell division protein CrgA Hum_adeno_E3A PF05393.11 CCC69612.1 - 0.22 11.5 4.7 1.2 9.1 0.1 2.6 1 1 1 2 2 2 0 Human adenovirus early E3A glycoprotein TatC PF00902.18 CCC69612.1 - 0.38 10.6 9.3 0.25 11.1 4.7 2.1 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) DUF2768 PF10966.8 CCC69612.1 - 0.91 10.0 13.5 0.24 11.9 0.5 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2768) DUF4149 PF13664.6 CCC69612.1 - 2.4 8.5 8.8 2.4 8.5 3.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) EphA2_TM PF14575.6 CCC69612.1 - 2.8 8.9 4.3 2.9 8.9 0.0 2.6 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF2663 PF10864.8 CCC69612.1 - 4.4 7.7 4.9 1.4 9.3 1.4 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) CDC13_N PF16853.5 CCC69613.1 - 5.2e-76 254.8 21.0 9.6e-76 254.0 13.7 2.7 2 0 0 2 2 2 2 Cell division control protein 13 N-terminus Cdc13_OB4_dimer PF18233.1 CCC69613.1 - 1.2e-16 60.8 0.1 1.9e-07 31.2 0.0 3.0 1 1 1 2 2 2 2 Cdc13 OB4 dimerization domain Cdc13_OB2 PF18691.1 CCC69613.1 - 1.3e-13 51.0 1.4 4.4e-13 49.3 0.4 2.6 2 0 0 2 2 2 1 Cell division control protein 13, OB2 domain POT1 PF02765.17 CCC69613.1 - 1e-07 31.9 0.4 1e-07 31.9 0.4 2.4 2 0 0 2 2 2 1 Telomeric single stranded DNA binding POT1/CDC13 Tyr_Deacylase PF02580.16 CCC69614.1 - 1.7e-43 148.6 0.1 1.8e-43 148.5 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase MARVEL PF01284.23 CCC69615.1 - 4.9e-25 88.2 13.2 6.8e-25 87.8 13.2 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF2755 PF10954.8 CCC69615.1 - 0.055 13.4 1.0 4 7.4 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) DUF4834 PF16118.5 CCC69615.1 - 0.48 11.4 0.1 0.48 11.4 0.1 2.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) MMPL PF03176.15 CCC69615.1 - 1.4 7.8 4.7 7.2 5.4 1.1 2.2 2 0 0 2 2 2 0 MMPL family TcpE PF12648.7 CCC69615.1 - 2.1 8.9 4.3 2.5 8.7 0.8 2.2 2 0 0 2 2 2 0 TcpE family Arm PF00514.23 CCC69617.1 - 1.7e-86 281.9 12.3 1.6e-14 53.3 0.2 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 CCC69617.1 - 5.5e-26 90.8 4.9 2.2e-25 88.9 5.0 2.0 2 0 0 2 2 2 1 Importin beta binding domain Arm_3 PF16186.5 CCC69617.1 - 6.9e-21 73.6 1.2 6.5e-20 70.5 1.9 2.1 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 CCC69617.1 - 3.6e-20 72.1 0.9 5.6e-07 29.9 0.1 5.2 4 2 0 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 CCC69617.1 - 2.7e-15 56.5 0.0 0.00023 21.5 0.0 4.6 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.22 CCC69617.1 - 2.5e-10 39.7 0.0 0.13 12.5 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat Arm_2 PF04826.13 CCC69617.1 - 1.4e-08 34.5 0.2 0.18 11.2 0.0 4.7 2 1 2 5 5 5 2 Armadillo-like V-ATPase_H_C PF11698.8 CCC69617.1 - 1.3e-05 25.3 0.0 0.06 13.5 0.0 3.9 4 1 0 4 4 4 1 V-ATPase subunit H RICTOR_V PF14668.6 CCC69617.1 - 2e-05 24.7 1.0 0.031 14.5 0.0 4.4 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Atx10homo_assoc PF09759.9 CCC69617.1 - 0.00078 19.4 0.1 1.6 8.8 0.0 4.5 4 1 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Cnd1 PF12717.7 CCC69617.1 - 0.0033 17.5 0.2 5.8 6.9 0.0 3.4 1 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 RICTOR_N PF14664.6 CCC69617.1 - 0.011 14.8 0.1 0.071 12.1 0.0 2.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term HEAT_PBS PF03130.16 CCC69617.1 - 0.013 16.1 3.8 1.8 9.4 0.0 5.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat DCB PF16213.5 CCC69617.1 - 0.076 12.7 0.0 0.52 10.0 0.0 2.3 2 1 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 Tim17 PF02466.19 CCC69618.1 - 1.8e-37 128.1 4.6 2.3e-37 127.7 4.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family JAB PF01398.21 CCC69619.1 - 1.9e-31 108.5 0.1 4.7e-31 107.2 0.1 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 CCC69619.1 - 6.3e-06 26.0 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 CCC69619.1 - 0.00049 20.2 0.1 0.0012 19.0 0.1 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0172) DNA_primase_S PF01896.19 CCC69619.1 - 0.027 14.5 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 DNA primase small subunit ELFV_dehydrog PF00208.21 CCC69620.1 - 6.4e-62 209.4 0.0 1.3e-61 208.4 0.0 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 CCC69620.1 - 9.9e-18 63.2 0.1 1.8e-12 45.7 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 CCC69620.1 - 0.0028 17.5 0.0 0.0082 16.0 0.0 1.7 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Cadherin_2 PF08266.12 CCC69620.1 - 0.018 14.9 0.0 0.68 9.8 0.0 2.7 2 0 0 2 2 2 0 Cadherin-like LMWSLP_N PF12211.8 CCC69620.1 - 0.18 11.4 0.8 23 4.5 0.0 3.2 3 0 0 3 3 3 0 Low molecular weight S layer protein N terminal Pkinase PF00069.25 CCC69621.1 - 5.7e-48 163.6 0.0 8.9e-48 162.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69621.1 - 6.4e-20 71.5 0.0 1.1e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCC69621.1 - 0.013 14.4 2.5 0.032 13.2 2.5 1.7 1 1 0 1 1 1 0 Haspin like kinase domain FTA2 PF13095.6 CCC69621.1 - 0.032 13.9 0.4 8.8 5.9 0.1 2.6 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCC69621.1 - 0.037 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.22 CCC69622.1 - 4.8e-05 23.1 0.0 8.9e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC69622.1 - 0.0013 18.8 0.0 0.0043 17.1 0.0 1.8 1 1 1 2 2 2 1 RNA recognition motif Ras PF00071.22 CCC69623.1 - 4.6e-42 143.4 0.0 6.2e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC69623.1 - 9.7e-19 67.8 0.0 3.1e-18 66.1 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC69623.1 - 2.9e-06 26.8 0.1 6.6e-06 25.7 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family SHR3_chaperone PF08229.11 CCC69624.1 - 7.5e-73 243.5 3.9 7.5e-73 243.5 3.9 1.3 1 1 1 2 2 2 1 ER membrane protein SH3 COX14 PF14880.6 CCC69624.1 - 3.1 7.7 5.4 7 6.6 0.1 2.8 3 0 0 3 3 3 0 Cytochrome oxidase c assembly Vpu PF00558.19 CCC69625.1 - 0.2 11.5 0.1 0.33 10.8 0.1 1.3 1 0 0 1 1 1 0 Vpu protein AMPK1_CBM PF16561.5 CCC69626.1 - 1e-14 54.5 0.3 2e-14 53.6 0.3 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBM_48 PF02922.18 CCC69626.1 - 0.082 13.3 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) dCMP_cyt_deam_1 PF00383.23 CCC69627.1 - 2.5e-28 97.9 1.9 3.7e-28 97.4 1.9 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCC69627.1 - 5.1e-17 61.9 0.2 1e-16 60.9 0.2 1.5 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 CCC69627.1 - 0.0039 17.3 3.0 0.027 14.6 0.3 2.5 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 TPR_20 PF14561.6 CCC69627.1 - 0.023 15.0 0.3 0.046 14.1 0.3 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat APOBEC4_like PF18774.1 CCC69627.1 - 0.028 14.3 0.4 0.064 13.2 0.4 1.5 1 0 0 1 1 1 0 APOBEC4-like -AID/APOBEC-deaminase APOBEC_N PF08210.11 CCC69627.1 - 0.051 13.5 3.0 0.076 12.9 1.3 2.2 2 1 0 2 2 2 0 APOBEC-like N-terminal domain TPR_12 PF13424.6 CCC69627.1 - 0.081 13.2 0.2 12 6.3 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat APOBEC2 PF18772.1 CCC69627.1 - 0.35 10.9 2.6 2.9 7.9 0.3 2.4 2 0 0 2 2 2 0 APOBEC2 NAD1 PF18778.1 CCC69627.1 - 0.37 10.8 2.7 0.6 10.2 0.5 2.2 2 0 0 2 2 2 0 Novel AID APOBEC clade 1 DNA_RNApol_7kD PF03604.13 CCC69628.1 - 1.1e-16 60.2 1.7 1.4e-16 59.9 1.7 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit zf_UBZ PF18439.1 CCC69628.1 - 0.004 16.7 0.8 1.5 8.5 0.1 2.2 2 0 0 2 2 2 2 Ubiquitin-Binding Zinc Finger DZR PF12773.7 CCC69628.1 - 0.0064 16.5 0.4 0.0088 16.0 0.4 1.3 1 0 0 1 1 1 1 Double zinc ribbon TFIIS_C PF01096.18 CCC69628.1 - 0.0093 15.8 0.7 3.9 7.4 0.1 2.3 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) HypA PF01155.19 CCC69628.1 - 0.015 15.3 0.2 0.015 15.3 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc-ribbons_6 PF07191.12 CCC69628.1 - 0.019 14.9 0.4 0.025 14.6 0.4 1.3 1 0 0 1 1 1 0 zinc-ribbons MCM_OB PF17207.3 CCC69628.1 - 0.026 14.3 0.3 0.029 14.2 0.3 1.1 1 0 0 1 1 1 0 MCM OB domain zinc_ribbon_10 PF10058.9 CCC69628.1 - 0.066 12.9 0.2 0.65 9.8 0.0 2.0 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Ribosomal_L40e PF01020.17 CCC69628.1 - 0.08 12.9 2.4 0.11 12.4 2.4 1.3 1 0 0 1 1 1 0 Ribosomal L40e family DUF4428 PF14471.6 CCC69628.1 - 0.086 12.8 1.4 1.5 8.8 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) Zn_ribbon_SprT PF17283.2 CCC69628.1 - 0.093 12.7 2.5 0.15 12.0 1.8 1.7 1 1 2 3 3 3 0 SprT-like zinc ribbon domain DUF2197 PF09963.9 CCC69628.1 - 0.11 12.8 2.4 7.4 6.9 0.2 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) FYDLN_acid PF09538.10 CCC69628.1 - 0.15 12.7 0.5 0.17 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn-ribbon_8 PF09723.10 CCC69628.1 - 0.23 11.6 3.2 0.81 9.9 3.1 1.9 1 1 2 3 3 3 0 Zinc ribbon domain Zn_ribbon_recom PF13408.6 CCC69628.1 - 0.25 11.9 2.9 3.7 8.1 0.6 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Rubredoxin_2 PF18073.1 CCC69628.1 - 0.53 10.1 2.7 9.7 6.0 0.3 2.2 2 0 0 2 2 2 0 Rubredoxin metal binding domain Ribosomal_L44 PF00935.19 CCC69628.1 - 1.6 9.3 5.1 13 6.3 0.7 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 PAP1 PF08601.10 CCC69629.1 - 2 8.1 17.1 2.5 7.7 17.1 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Chs7 PF12271.8 CCC69630.1 - 5.4e-116 387.0 20.0 6.2e-116 386.8 20.0 1.0 1 0 0 1 1 1 1 Chitin synthase export chaperone Ribosomal_L44 PF00935.19 CCC69631.1 - 7.7e-36 122.4 11.1 1.1e-35 121.9 11.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Far-17a_AIG1 PF04750.14 CCC69632.1 - 2.2e-08 33.7 1.5 2.7e-08 33.4 1.5 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein Arrestin_C PF02752.22 CCC69634.1 - 1.2e-22 80.8 1.3 2.6e-22 79.7 0.1 2.2 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 CCC69634.1 - 9e-08 32.3 0.0 5e-06 26.6 0.0 2.4 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.7 CCC69634.1 - 0.0023 17.7 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like ANAPC4_WD40 PF12894.7 CCC69635.1 - 6.1e-08 32.9 0.0 0.068 13.5 0.0 3.7 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCC69635.1 - 2.8e-07 31.1 0.0 0.028 15.3 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CCC69635.1 - 0.037 13.0 0.0 0.095 11.6 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein CNH PF00780.22 CCC69635.1 - 0.066 12.8 0.0 0.2 11.2 0.0 1.8 1 1 0 1 1 1 0 CNH domain PIP5K PF01504.18 CCC69636.1 - 2.8e-42 144.8 0.3 1.9e-36 125.7 0.7 4.6 3 2 1 4 4 4 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 CCC69636.1 - 5.1e-28 98.0 0.0 9.7e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.21 CCC69636.1 - 1.5e-16 60.2 9.7 1.5e-16 60.2 9.7 2.0 2 0 0 2 2 2 1 FYVE zinc finger Peptidase_M28 PF04389.17 CCC69637.1 - 6.4e-39 133.7 0.0 1e-38 133.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 DUF4678 PF15727.5 CCC69638.1 - 0.022 14.0 3.2 0.025 13.8 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4678) DUF5544 PF17698.1 CCC69638.1 - 0.076 13.1 0.5 0.13 12.4 0.4 1.3 1 1 0 1 1 1 0 Family of unknown function (DUF5544) ABC_tran PF00005.27 CCC69639.1 - 7.9e-47 159.2 0.9 3.4e-23 82.7 0.0 3.2 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 CCC69639.1 - 1.6e-20 72.9 9.0 1.6e-20 72.9 9.0 2.6 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.6 CCC69639.1 - 6.1e-17 62.4 9.5 3.3e-05 23.9 0.0 5.1 3 2 1 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCC69639.1 - 2.6e-11 43.4 0.0 0.00048 19.6 0.0 3.4 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 CCC69639.1 - 9.6e-07 29.3 0.0 0.043 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CCC69639.1 - 2e-06 27.4 0.0 0.11 12.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 CCC69639.1 - 3e-06 27.6 2.0 0.091 13.0 0.0 3.1 3 1 0 3 3 2 2 AAA domain NACHT PF05729.12 CCC69639.1 - 3.3e-06 27.1 0.0 0.02 14.8 0.0 2.6 2 0 0 2 2 2 2 NACHT domain RsgA_GTPase PF03193.16 CCC69639.1 - 3.8e-06 26.9 0.1 0.084 12.8 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CCC69639.1 - 1e-05 25.9 0.1 0.32 11.3 0.0 3.2 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CCC69639.1 - 2.5e-05 24.3 0.1 0.11 12.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 CCC69639.1 - 3.8e-05 24.1 0.0 0.076 13.4 0.1 3.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 CCC69639.1 - 3.8e-05 24.2 6.2 0.1 13.2 0.1 4.1 5 0 0 5 5 3 2 AAA domain AAA_14 PF13173.6 CCC69639.1 - 4.2e-05 23.6 0.1 0.37 10.8 0.0 3.4 2 1 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 CCC69639.1 - 0.00013 21.9 0.1 0.24 11.3 0.0 2.7 2 0 0 2 2 2 2 NTPase ATP-synt_ab PF00006.25 CCC69639.1 - 0.0002 21.1 0.0 0.035 13.7 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.6 CCC69639.1 - 0.00022 21.0 0.0 0.15 11.8 0.0 3.4 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 CCC69639.1 - 0.00031 20.5 0.1 0.31 10.8 0.0 2.9 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 CCC69639.1 - 0.00041 20.9 27.6 0.13 12.7 0.0 5.2 5 0 0 5 5 5 2 AAA domain AAA_24 PF13479.6 CCC69639.1 - 0.00049 19.9 0.0 1.3 8.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 CCC69639.1 - 0.00049 20.3 1.1 0.3 11.2 0.0 3.1 3 1 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 CCC69639.1 - 0.00061 20.1 0.0 0.6 10.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.12 CCC69639.1 - 0.0012 18.1 0.5 0.3 10.3 0.0 2.8 3 0 0 3 3 2 1 Zeta toxin Roc PF08477.13 CCC69639.1 - 0.0013 18.9 0.1 1.7 8.9 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 CCC69639.1 - 0.0014 17.7 0.0 0.33 9.9 0.0 2.5 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB NB-ARC PF00931.22 CCC69639.1 - 0.0014 17.9 0.0 0.54 9.4 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 CCC69639.1 - 0.0016 18.0 0.0 0.41 10.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 CCC69639.1 - 0.0025 17.8 0.1 3.8 7.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 CCC69639.1 - 0.0038 17.2 0.0 0.58 10.2 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2813 PF11398.8 CCC69639.1 - 0.0043 16.4 4.5 0.3 10.3 0.0 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF2813) Dynamin_N PF00350.23 CCC69639.1 - 0.0058 16.7 3.5 0.5 10.4 0.0 3.7 4 0 0 4 4 3 1 Dynamin family DUF815 PF05673.13 CCC69639.1 - 0.0059 15.8 0.0 2.7 7.1 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_15 PF13175.6 CCC69639.1 - 0.0081 15.9 28.4 0.058 13.1 0.0 4.9 2 1 2 4 4 3 2 AAA ATPase domain Pox_A32 PF04665.12 CCC69639.1 - 0.0092 15.5 1.2 0.75 9.2 0.0 3.1 3 0 0 3 3 3 1 Poxvirus A32 protein MobB PF03205.14 CCC69639.1 - 0.0093 15.9 0.0 0.21 11.5 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B G-alpha PF00503.20 CCC69639.1 - 0.01 15.0 5.0 0.25 10.4 0.0 3.0 3 1 0 3 3 3 0 G-protein alpha subunit AAA_25 PF13481.6 CCC69639.1 - 0.017 14.7 0.0 1.4 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain Septin PF00735.18 CCC69639.1 - 0.018 14.3 0.4 5.2 6.3 0.1 2.7 2 1 0 2 2 2 0 Septin FeoB_N PF02421.18 CCC69639.1 - 0.021 14.4 0.0 7.6 6.1 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B SRP54 PF00448.22 CCC69639.1 - 0.035 13.7 0.1 2.4 7.7 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Rad17 PF03215.15 CCC69639.1 - 0.039 13.9 0.0 1 9.2 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain cobW PF02492.19 CCC69639.1 - 0.044 13.4 0.1 5.7 6.5 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 CCC69639.1 - 0.05 13.9 0.1 21 5.4 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Arf PF00025.21 CCC69639.1 - 0.054 13.0 0.0 0.74 9.2 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Ras PF00071.22 CCC69639.1 - 0.079 12.6 1.0 8.4 6.0 0.0 3.2 3 0 0 3 3 3 0 Ras family FtsK_SpoIIIE PF01580.18 CCC69639.1 - 0.11 11.9 0.0 2 7.7 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.6 CCC69639.1 - 0.35 11.3 6.2 12 6.4 0.0 4.0 3 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 CCC69639.1 - 0.46 10.8 2.8 0.8 10.0 0.0 2.8 3 1 0 3 3 3 0 AAA domain ATPase_2 PF01637.18 CCC69639.1 - 0.48 10.3 0.0 0.48 10.3 0.0 3.0 4 0 0 4 4 2 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 CCC69639.1 - 0.71 9.9 0.0 0.71 9.9 0.0 4.5 4 1 1 5 5 5 0 Helicase HerA, central domain RNB PF00773.19 CCC69640.1 - 6.3e-97 324.8 0.1 2.1e-96 323.1 0.0 1.8 2 0 0 2 2 2 1 RNB domain Rrp44_CSD1 PF17216.3 CCC69640.1 - 1.8e-73 245.1 0.1 6.8e-73 243.2 0.1 2.1 2 0 0 2 2 2 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CCC69640.1 - 2.3e-31 107.6 1.9 6.3e-31 106.2 1.9 1.8 1 0 0 1 1 1 1 S1 domain OB_Dis3 PF17849.1 CCC69640.1 - 1.4e-16 60.3 0.0 3.4e-16 59.0 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 CCC69640.1 - 5.7e-15 55.8 1.4 1.4e-14 54.5 1.4 1.6 1 0 0 1 1 1 1 PIN domain CSD2 PF17876.1 CCC69640.1 - 0.00097 19.3 0.0 0.13 12.5 0.0 2.9 2 0 0 2 2 2 1 Cold shock domain PIN_12 PF16289.5 CCC69640.1 - 0.056 13.9 2.4 0.21 12.1 2.2 2.2 1 1 0 1 1 1 0 PIN domain Dis3l2_C_term PF17877.1 CCC69640.1 - 0.083 13.2 0.2 0.083 13.2 0.2 2.0 2 0 0 2 2 2 0 DIS3-like exonuclease 2 C terminal Big_3 PF07523.12 CCC69640.1 - 0.18 12.1 0.4 1.7 9.0 0.2 2.5 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 3) UCH PF00443.29 CCC69641.1 - 3.3e-50 171.0 4.7 4.2e-50 170.6 4.7 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCC69641.1 - 3.6e-13 49.8 11.2 1.4e-12 47.9 11.2 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 CCC69641.1 - 0.00056 19.6 0.2 0.0037 17.0 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin family Amidase02_C PF12123.8 CCC69641.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase DUF1690 PF07956.11 CCC69642.1 - 3.5e-35 121.4 12.5 4e-35 121.2 12.5 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) AKNA PF12443.8 CCC69642.1 - 0.0031 18.1 2.7 0.0054 17.4 2.7 1.6 1 0 0 1 1 1 1 AT-hook-containing transcription factor Not3 PF04065.15 CCC69642.1 - 0.024 14.1 11.6 0.049 13.0 10.4 1.9 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component InvH PF04741.12 CCC69642.1 - 0.083 12.8 1.1 0.099 12.6 1.1 1.3 1 0 0 1 1 1 0 InvH outer membrane lipoprotein DUF4140 PF13600.6 CCC69642.1 - 0.5 10.8 6.2 1.1 9.7 6.2 1.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) WHIM1 PF15612.6 CCC69643.1 - 2.6e-08 33.2 0.2 1.2e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF349 PF03993.12 CCC69643.1 - 0.067 13.5 3.4 0.17 12.2 1.8 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) FAD_oxidored PF12831.7 CCC69643.1 - 0.092 12.1 0.4 0.15 11.4 0.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pkinase PF00069.25 CCC69644.1 - 5.5e-70 235.7 0.0 8.5e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69644.1 - 3.7e-39 134.6 0.0 6.7e-39 133.7 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC69644.1 - 0.0068 15.2 0.8 0.014 14.2 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CCC69644.1 - 0.0078 15.6 0.1 0.051 12.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 CCC69644.1 - 0.021 14.2 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EssA PF10661.9 CCC69644.1 - 0.026 14.4 1.2 0.05 13.4 1.2 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA ABC1 PF03109.16 CCC69644.1 - 0.027 14.6 0.0 0.093 12.9 0.0 1.9 2 0 0 2 2 2 0 ABC1 family Glycogen_syn PF05693.13 CCC69645.1 - 0 1132.6 0.0 0 1132.4 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 CCC69645.1 - 9.5e-08 31.8 0.0 1.5e-05 24.6 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCC69645.1 - 3.3e-06 27.6 0.0 0.0019 18.6 0.0 2.7 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCC69645.1 - 5.2e-05 23.3 0.2 0.00011 22.3 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 CCC69645.1 - 0.00038 20.2 0.0 0.00072 19.3 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.6 CCC69645.1 - 0.00056 20.4 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain SH3BGR PF04908.15 CCC69646.1 - 0.00045 20.3 0.0 0.022 14.9 0.0 3.5 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Ferric_reduct PF01794.19 CCC69647.1 - 2.6e-18 66.3 11.4 2.6e-18 66.3 11.4 2.3 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CCC69647.1 - 1.9e-09 37.9 0.0 3.6e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CCC69647.1 - 0.00018 21.6 0.4 0.00048 20.2 0.1 1.8 2 1 0 2 2 2 1 FAD-binding domain MerC PF03203.14 CCC69647.1 - 8.1 6.9 13.0 0.15 12.5 1.0 2.9 2 1 1 3 3 3 0 MerC mercury resistance protein OCD_Mu_crystall PF02423.15 CCC69648.1 - 3.9e-07 29.3 0.0 7.3e-07 28.4 0.0 1.3 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family PCRF PF03462.18 CCC69650.1 - 1.5e-54 184.8 1.6 3.9e-54 183.5 0.0 2.0 2 0 0 2 2 2 1 PCRF domain RF-1 PF00472.20 CCC69650.1 - 1.2e-37 128.4 4.2 1.2e-37 128.4 4.2 1.9 2 0 0 2 2 2 1 RF-1 domain MIR PF02815.19 CCC69650.1 - 0.064 13.1 0.6 0.26 11.1 0.2 2.2 2 1 0 2 2 2 0 MIR domain AAA_23 PF13476.6 CCC69650.1 - 0.11 13.0 7.4 2 8.9 4.1 2.2 2 0 0 2 2 2 0 AAA domain Mating_N PF12731.7 CCC69650.1 - 0.14 12.2 2.9 0.17 12.0 1.4 1.9 2 1 0 2 2 2 0 Mating-type protein beta 1 UPF0029 PF01205.19 CCC69651.1 - 1.4e-31 108.9 0.1 3.2e-31 107.8 0.1 1.5 1 1 0 1 1 1 1 Uncharacterized protein family UPF0029 Pkinase PF00069.25 CCC69652.1 - 1.2e-59 201.8 0.0 4e-59 200.1 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69652.1 - 3.8e-25 88.6 0.0 1.1e-24 87.1 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC69652.1 - 0.00041 19.8 0.1 0.36 10.1 0.1 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 CCC69652.1 - 0.00072 19.0 1.3 0.0011 18.4 0.3 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 CCC69652.1 - 0.0014 18.3 0.1 0.0074 15.9 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCC69652.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCC69652.1 - 0.035 12.9 0.9 0.05 12.4 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase LT-IIB PF06453.11 CCC69652.1 - 0.069 13.0 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) Glyco_hydro_38N PF01074.22 CCC69653.1 - 1.3e-82 277.4 0.1 2.1e-82 276.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 CCC69653.1 - 1.8e-52 178.5 0.5 4.4e-52 177.3 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 CCC69653.1 - 6.8e-26 90.3 0.0 1.2e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 CCC69653.1 - 7.3e-08 32.4 1.1 4.6e-07 29.9 0.1 2.8 3 0 0 3 3 3 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Prenyltrans PF00432.21 CCC69654.1 - 3.9e-29 100.1 6.0 7.9e-08 31.9 0.0 5.5 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 CCC69654.1 - 0.0014 17.8 0.0 0.0031 16.6 0.0 1.6 1 1 0 1 1 1 1 Squalene-hopene cyclase C-terminal domain TED_complement PF07678.14 CCC69654.1 - 0.023 13.8 0.1 0.14 11.2 0.0 2.2 2 1 1 3 3 3 0 A-macroglobulin TED domain ACPS PF01648.20 CCC69655.1 - 3.7e-13 49.6 0.0 7.1e-13 48.7 0.0 1.5 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF4105 PF13387.6 CCC69655.1 - 0.019 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4105) Pex14_N PF04695.13 CCC69656.1 - 6.5e-28 98.4 2.2 6.5e-28 98.4 2.2 3.4 3 1 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.12 CCC69656.1 - 0.00016 21.8 9.5 0.00031 20.8 9.5 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF812 PF05667.11 CCC69656.1 - 0.00048 19.2 7.2 0.00065 18.7 7.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) zf-C4H2 PF10146.9 CCC69656.1 - 0.0024 18.2 7.7 0.0024 18.2 7.7 1.6 2 0 0 2 2 1 1 Zinc finger-containing protein Herpes_UL6 PF01763.16 CCC69656.1 - 0.024 13.2 4.5 0.035 12.6 4.5 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like FapA PF03961.13 CCC69656.1 - 0.024 13.2 8.0 0.039 12.6 8.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF1366 PF07104.11 CCC69656.1 - 0.046 13.4 4.0 0.12 12.1 4.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Tup_N PF08581.10 CCC69656.1 - 0.063 13.6 14.3 0.046 14.0 12.1 1.9 2 0 0 2 2 1 0 Tup N-terminal FlgN PF05130.12 CCC69656.1 - 0.07 13.6 11.6 0.15 12.6 11.6 1.5 1 0 0 1 1 1 0 FlgN protein Nsp1_C PF05064.13 CCC69656.1 - 0.07 12.9 11.2 1.8 8.4 2.1 2.7 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF4200 PF13863.6 CCC69656.1 - 0.11 12.9 15.7 0.13 12.6 14.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Prominin PF05478.11 CCC69656.1 - 0.15 9.9 4.9 0.23 9.4 4.9 1.3 1 0 0 1 1 1 0 Prominin V_ATPase_I PF01496.19 CCC69656.1 - 0.16 9.9 7.9 0.24 9.3 7.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1043 PF06295.12 CCC69656.1 - 0.2 11.7 11.8 2.2 8.3 11.8 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Vps51 PF08700.11 CCC69656.1 - 0.34 11.0 10.1 0.16 12.1 6.8 2.2 2 0 0 2 2 1 0 Vps51/Vps67 Vps53_N PF04100.12 CCC69656.1 - 0.44 9.4 11.5 0.65 8.9 11.5 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF4407 PF14362.6 CCC69656.1 - 0.48 9.7 10.8 0.044 13.2 6.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) CCDC-167 PF15188.6 CCC69656.1 - 0.5 10.7 12.0 2.3e+02 2.2 10.4 2.9 1 1 1 2 2 1 0 Coiled-coil domain-containing protein 167 Exonuc_VII_L PF02601.15 CCC69656.1 - 0.5 9.9 5.4 0.78 9.3 5.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit IF-2B PF01008.17 CCC69656.1 - 0.55 9.4 5.4 0.99 8.6 5.4 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family GTP-bdg_M PF16360.5 CCC69656.1 - 0.57 10.8 4.4 0.86 10.2 0.9 2.6 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region Rx_N PF18052.1 CCC69656.1 - 0.83 10.0 8.1 5 7.5 0.7 2.9 1 1 1 2 2 2 0 Rx N-terminal domain Spc7 PF08317.11 CCC69656.1 - 0.88 8.4 19.0 0.15 10.9 15.0 1.7 2 0 0 2 2 1 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 CCC69656.1 - 1.3 8.4 16.8 2.3 7.6 16.8 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 Phage_GPO PF05929.11 CCC69656.1 - 1.5 8.3 8.7 3.3 7.3 8.7 1.6 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF1664 PF07889.12 CCC69656.1 - 1.6 8.7 12.1 5.7 7.0 9.6 2.8 2 1 1 3 3 2 0 Protein of unknown function (DUF1664) Fez1 PF06818.15 CCC69656.1 - 1.6 9.1 14.7 7.6 6.9 14.9 2.0 1 1 0 1 1 1 0 Fez1 DUF641 PF04859.12 CCC69656.1 - 1.8 8.9 7.9 6.9 7.0 7.9 2.0 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF1640 PF07798.11 CCC69656.1 - 2 8.5 15.2 4.3 7.3 15.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Syntaxin-6_N PF09177.11 CCC69656.1 - 2.2 8.9 9.8 8.4 7.0 2.4 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal HIP1_clath_bdg PF16515.5 CCC69656.1 - 3.3 8.4 18.4 0.16 12.6 10.8 2.6 2 1 1 3 3 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 CCC69656.1 - 4.9 7.7 21.3 1.3 9.6 16.9 2.3 2 1 0 2 2 1 0 Apg6 coiled-coil region DUF5446 PF17522.2 CCC69656.1 - 5.1 7.3 12.0 3.4 7.9 6.6 2.7 2 1 1 3 3 3 0 Family of unknown function (DUF5446) FAM76 PF16046.5 CCC69656.1 - 5.4 6.3 8.3 0.51 9.7 3.9 1.7 2 0 0 2 2 2 0 FAM76 protein CHD5 PF04420.14 CCC69656.1 - 6.2 6.7 6.7 2.4 8.0 2.3 2.2 1 1 1 2 2 2 0 CHD5-like protein YabA PF06156.13 CCC69656.1 - 7.5 7.3 14.2 4.7 7.9 7.8 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Med5 PF08689.10 CCC69657.1 - 0 1502.1 53.6 0 1502.0 53.6 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 SNF2_N PF00176.23 CCC69658.1 - 4.1e-66 223.1 2.5 4.1e-66 223.1 2.5 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 CCC69658.1 - 3.5e-46 156.9 21.1 3.5e-46 156.9 21.1 3.7 3 1 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 CCC69658.1 - 2.4e-17 63.3 0.0 2.4e-17 63.3 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Fe_hyd_lg_C PF02906.14 CCC69658.1 - 0.033 13.9 4.0 0.1 12.3 4.0 1.8 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Chorismate_synt PF01264.21 CCC69659.1 - 1.2e-138 461.3 0.1 1.4e-138 461.1 0.1 1.0 1 0 0 1 1 1 1 Chorismate synthase AFP_2 PF18815.1 CCC69659.1 - 0.037 14.3 0.1 2.3 8.6 0.2 2.4 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat Ribosomal_L6 PF00347.23 CCC69660.1 - 4.2e-30 104.2 12.9 3.2e-15 56.6 5.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 CPT_N PF16484.5 CCC69660.1 - 0.17 11.9 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 Carnitine O-palmitoyltransferase N-terminus RNase_PH PF01138.21 CCC69661.1 - 7.8e-06 26.4 0.2 1.6e-05 25.4 0.2 1.5 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCC69661.1 - 0.03 14.4 0.0 0.058 13.4 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 EMP24_GP25L PF01105.24 CCC69662.1 - 1.1e-07 32.0 0.2 1.7e-07 31.4 0.2 1.3 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RINT1_TIP1 PF04437.13 CCC69663.1 - 9.7e-91 305.1 26.9 9.7e-91 305.1 26.9 2.0 2 1 0 2 2 2 1 RINT-1 / TIP-1 family Halogen_Hydrol PF10112.9 CCC69663.1 - 0.063 13.3 3.8 0.66 10.0 0.1 2.8 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein ARID PF01388.21 CCC69663.1 - 0.092 13.4 0.2 1.1 10.0 0.0 2.9 2 1 0 2 2 2 0 ARID/BRIGHT DNA binding domain DUF676 PF05057.14 CCC69664.1 - 3.6e-57 193.4 0.0 6.2e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.15 CCC69664.1 - 0.002 17.3 0.0 0.0047 16.2 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 CCC69664.1 - 0.084 12.7 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 CCC69664.1 - 0.098 12.4 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein PP2C PF00481.21 CCC69665.1 - 1.2e-55 188.9 0.1 2.4e-55 188.0 0.1 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 CCC69665.1 - 5.7e-41 138.1 70.9 1.6e-09 37.4 1.8 10.2 7 2 2 10 10 10 7 Leucine rich repeat LRR_4 PF12799.7 CCC69665.1 - 1.1e-31 108.3 82.1 5.2e-07 29.9 1.7 13.5 5 4 11 16 16 16 13 Leucine Rich repeats (2 copies) Guanylate_cyc PF00211.20 CCC69665.1 - 3e-28 98.7 0.0 6.5e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ad_cyc_g-alpha PF08509.11 CCC69665.1 - 5.7e-05 22.8 0.3 5.7e-05 22.8 0.3 2.9 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_9 PF14580.6 CCC69665.1 - 6.5e-05 22.5 27.0 0.0019 17.7 4.5 5.2 3 1 2 5 5 5 3 Leucine-rich repeat LRR_6 PF13516.6 CCC69665.1 - 0.00043 20.1 55.7 2.6 8.3 0.1 15.0 16 0 0 16 16 16 4 Leucine Rich repeat PP2C_2 PF13672.6 CCC69665.1 - 0.04 13.6 0.2 0.13 11.9 0.0 1.9 2 0 0 2 2 2 0 Protein phosphatase 2C LRR_2 PF07723.13 CCC69665.1 - 0.88 10.4 3.0 24 5.8 0.2 3.9 3 1 1 4 4 4 0 Leucine Rich Repeat HECT PF00632.25 CCC69666.1 - 9.3e-87 291.4 1.3 1.8e-86 290.4 1.3 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 CCC69666.1 - 0.0037 16.9 0.2 0.0075 16.0 0.2 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif Glyco_transf_22 PF03901.17 CCC69667.1 - 1.1e-107 360.8 35.8 1.3e-107 360.6 35.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family SPRY PF00622.28 CCC69668.1 - 7.1e-10 39.0 0.0 2e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 SPRY domain DUF5083 PF16890.5 CCC69668.1 - 0.019 14.7 1.5 0.037 13.8 1.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5083) Myc_target_1 PF15179.6 CCC69668.1 - 0.032 14.1 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 Myc target protein 1 COX2_TM PF02790.15 CCC69668.1 - 0.15 12.3 1.9 0.27 11.4 1.9 1.4 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain Babuvirus_MP PF07234.11 CCC69668.1 - 0.15 12.2 0.9 0.27 11.4 0.9 1.3 1 0 0 1 1 1 0 Movement and RNA silencing protein Aldedh PF00171.22 CCC69669.1 - 2.9e-160 533.8 0.0 3.3e-160 533.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Cep3 PF16846.5 CCC69670.1 - 4.9e-223 741.2 19.7 5.7e-223 741.0 19.7 1.0 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit B Zn_clus PF00172.18 CCC69670.1 - 4.1e-07 30.0 8.6 9.1e-07 28.9 8.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mlh1_C PF16413.5 CCC69671.1 - 9.5e-83 277.7 0.1 1.7e-82 276.9 0.1 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 CCC69671.1 - 5.6e-31 106.7 2.1 1.2e-30 105.6 1.3 2.1 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 CCC69671.1 - 9.6e-13 48.1 0.1 2.9e-12 46.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CCC69671.1 - 9.3e-07 29.3 0.0 2.2e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mito_carr PF00153.27 CCC69672.1 - 1.2e-64 214.3 2.9 1.2e-24 86.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein LNS2 PF08235.13 CCC69673.1 - 2.3e-89 298.8 0.0 4.4e-67 225.9 0.0 2.2 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 CCC69673.1 - 1.3e-43 147.1 0.0 3.6e-43 145.7 0.0 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region Vezatin PF12632.7 CCC69675.1 - 0.001 18.5 5.6 0.001 18.5 5.6 2.7 2 2 0 2 2 2 1 Mysoin-binding motif of peroxisomes LEM PF03020.15 CCC69675.1 - 0.19 11.3 1.0 0.53 9.9 1.0 1.8 1 0 0 1 1 1 0 LEM domain Guanylin PF02058.15 CCC69675.1 - 0.22 12.0 1.9 6.6 7.3 0.1 3.2 2 1 0 2 2 2 0 Guanylin precursor PhoLip_ATPase_C PF16212.5 CCC69676.1 - 1.1e-65 221.8 23.4 1.1e-65 221.8 23.4 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCC69676.1 - 8.3e-23 79.9 4.2 8.3e-23 79.9 4.2 3.2 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 CCC69676.1 - 1e-12 48.0 0.0 2.9e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 CCC69676.1 - 9.5e-12 44.9 0.0 6.3e-11 42.2 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 CCC69676.1 - 2.8e-11 44.1 0.1 1.9e-05 25.0 0.0 3.5 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 CCC69676.1 - 0.0011 18.8 1.7 0.0091 15.8 0.4 2.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DnaJ PF00226.31 CCC69677.1 - 2.6e-25 88.3 2.0 4.2e-25 87.7 2.0 1.3 1 0 0 1 1 1 1 DnaJ domain TrmK PF04816.12 CCC69677.1 - 0.035 13.6 0.3 0.047 13.2 0.3 1.2 1 0 0 1 1 1 0 tRNA (adenine(22)-N(1))-methyltransferase DUF5312 PF17239.2 CCC69677.1 - 0.13 10.6 0.2 0.21 9.9 0.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5312) ATG16 PF08614.11 CCC69679.1 - 8.8e-11 42.4 10.1 3e-10 40.7 8.4 2.0 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.8 CCC69679.1 - 1.7e-05 25.0 7.7 4.7e-05 23.6 7.7 1.7 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding DUF4760 PF15956.5 CCC69679.1 - 0.0013 18.9 2.6 0.0019 18.3 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4760) HIP1_clath_bdg PF16515.5 CCC69679.1 - 0.005 17.4 3.7 0.005 17.4 3.7 2.0 1 1 1 2 2 2 1 Clathrin-binding domain of Huntingtin-interacting protein 1 HAUS-augmin3 PF14932.6 CCC69679.1 - 0.0067 16.0 5.0 0.0071 16.0 5.0 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 PKcGMP_CC PF16808.5 CCC69679.1 - 0.012 15.4 5.6 0.027 14.3 3.8 2.3 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase GAS PF13851.6 CCC69679.1 - 0.016 14.6 10.7 0.053 12.9 8.8 1.9 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Ferritin PF00210.24 CCC69679.1 - 0.018 15.0 1.6 0.02 14.8 1.3 1.4 1 1 0 1 1 1 0 Ferritin-like domain Spectrin PF00435.21 CCC69679.1 - 0.018 15.5 5.7 0.028 14.9 5.7 1.4 1 1 0 1 1 1 0 Spectrin repeat P4Ha_N PF08336.11 CCC69679.1 - 0.018 15.0 2.2 0.026 14.5 2.2 1.2 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF4201 PF13870.6 CCC69679.1 - 0.035 13.8 8.2 0.071 12.8 8.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) Syntaxin-6_N PF09177.11 CCC69679.1 - 0.045 14.3 4.4 0.19 12.3 4.4 1.8 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF4140 PF13600.6 CCC69679.1 - 0.053 14.0 3.0 0.17 12.3 3.0 1.9 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 CCC69679.1 - 0.06 13.9 7.6 0.07 13.7 7.6 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region RUN PF02759.19 CCC69679.1 - 0.077 12.9 0.3 0.095 12.7 0.3 1.3 1 0 0 1 1 1 0 RUN domain Seadorna_VP6 PF07407.11 CCC69679.1 - 0.13 11.1 3.2 0.15 11.0 3.2 1.2 1 0 0 1 1 1 0 Seadornavirus VP6 protein ABC_tran_CTD PF16326.5 CCC69679.1 - 0.47 10.7 9.6 0.68 10.2 6.1 2.7 1 1 2 3 3 3 0 ABC transporter C-terminal domain Fib_alpha PF08702.10 CCC69679.1 - 0.5 10.5 6.0 0.23 11.7 3.0 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.8 CCC69679.1 - 0.76 9.8 14.4 2.7 8.1 14.4 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding TPD52 PF04201.15 CCC69679.1 - 1.3 8.7 9.4 5.2 6.7 3.8 2.1 1 1 1 2 2 2 0 Tumour protein D52 family DUF16 PF01519.16 CCC69679.1 - 1.9 9.0 8.7 2.7 8.6 8.7 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF641 PF04859.12 CCC69679.1 - 3.1 8.1 8.7 0.8 10.0 3.0 2.3 1 1 1 3 3 3 0 Plant protein of unknown function (DUF641) YabA PF06156.13 CCC69679.1 - 3.3 8.4 9.1 6.3 7.5 8.9 1.7 1 1 0 1 1 1 0 Initiation control protein YabA SlyX PF04102.12 CCC69679.1 - 3.8 8.2 7.8 7.9 7.2 1.6 2.7 1 1 1 2 2 2 0 SlyX Cep57_CLD_2 PF14197.6 CCC69679.1 - 4.1 7.6 10.9 2.1 8.5 5.5 2.6 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 Ribosomal_S8 PF00410.19 CCC69680.1 - 4.3e-17 62.3 0.1 3.1e-16 59.5 0.1 2.0 1 1 0 1 1 1 1 Ribosomal protein S8 Ehbp PF10622.9 CCC69681.1 - 0.025 14.6 0.3 0.075 13.1 0.0 1.9 2 0 0 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) PNK3P PF08645.11 CCC69682.1 - 1.8e-42 144.8 0.9 2.2e-42 144.5 0.9 1.0 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase DUF2201 PF09967.9 CCC69682.1 - 0.13 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 VWA-like domain (DUF2201) MFS_1 PF07690.16 CCC69683.1 - 1.7e-11 43.7 17.0 1.7e-11 43.7 17.0 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.13 CCC69683.1 - 2.5e-08 33.7 7.2 2.5e-08 33.7 7.2 2.3 2 0 0 2 2 2 1 Nodulin-like DUF5377 PF17347.2 CCC69684.1 - 0.027 14.8 0.0 2.4 8.6 0.0 3.3 3 0 0 3 3 3 0 Family of unknown function (DUF5377) Nup35_RRM PF05172.13 CCC69685.1 - 2.3e-35 120.6 0.0 6.9e-35 119.1 0.0 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 CCC69685.1 - 0.00071 19.5 0.0 0.0016 18.4 0.0 1.6 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PepSY_TM PF03929.16 CCC69685.1 - 5.7 6.5 6.0 10 5.7 6.0 1.4 1 0 0 1 1 1 0 PepSY-associated TM region ADH_zinc_N_2 PF13602.6 CCC69686.1 - 1.6e-12 48.6 0.0 3.2e-12 47.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CCC69686.1 - 1.5e-09 37.9 0.0 3.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCC69686.1 - 4.4e-05 23.3 0.0 0.00024 21.0 0.0 2.1 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF4917 PF16263.5 CCC69686.1 - 0.14 11.5 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4917) Semialdhyde_dh PF01118.24 CCC69686.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 CCC69688.1 - 5.3e-13 50.2 0.0 1.2e-12 49.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CCC69688.1 - 2.1e-05 24.5 0.0 3.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 CCC69688.1 - 0.0059 17.0 0.0 0.024 15.1 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAGLU PF05089.12 CCC69688.1 - 0.12 11.3 0.1 0.19 10.6 0.1 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain ADH_zinc_N_2 PF13602.6 CCC69689.1 - 4.2e-12 47.3 0.0 4.4e-11 44.0 0.0 2.5 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 CCC69689.1 - 1.1e-07 31.9 0.0 3.7e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCC69689.1 - 9.5e-06 25.5 0.0 0.00036 20.4 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.24 CCC69689.1 - 0.013 16.0 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Peptidase_S24 PF00717.23 CCC69690.1 - 3e-07 30.3 0.0 2.2e-06 27.5 0.0 2.3 2 1 1 3 3 3 1 Peptidase S24-like Peptidase_S26 PF10502.9 CCC69690.1 - 0.0029 17.4 0.0 0.013 15.3 0.0 2.0 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Ribophorin_II PF05817.14 CCC69691.1 - 1e-13 50.7 1.3 1.3e-13 50.5 1.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Osw5 PF17062.5 CCC69692.1 - 5.7e-31 106.4 12.9 7.5e-31 106.0 12.9 1.2 1 0 0 1 1 1 1 Outer spore wall 5 Pex24p PF06398.11 CCC69692.1 - 0.023 13.7 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF948 PF06103.11 CCC69692.1 - 0.081 13.2 0.9 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Axin_b-cat_bind PF08833.10 CCC69692.1 - 0.1 12.7 0.2 0.1 12.7 0.2 2.2 3 0 0 3 3 3 0 Axin beta-catenin binding domain Ctr PF04145.15 CCC69692.1 - 1.9 9.1 4.5 4.1 8.0 4.5 1.7 1 1 0 1 1 1 0 Ctr copper transporter family WD40 PF00400.32 CCC69694.1 - 1.1e-24 86.2 1.5 7.3e-05 23.5 0.1 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC69694.1 - 2.4e-09 37.4 0.0 0.052 13.8 0.0 5.0 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCC69694.1 - 4.9e-06 26.6 0.1 0.036 13.9 0.1 3.6 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCC69694.1 - 0.0068 15.4 0.3 1.1 8.2 0.0 2.9 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 CCC69694.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.7 1 1 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain 4F5 PF04419.14 CCC69695.1 - 2.1e-08 34.9 9.3 2.1e-08 34.9 9.3 2.2 2 0 0 2 2 2 1 4F5 protein family PP28 PF10252.9 CCC69695.1 - 0.037 14.5 2.6 0.037 14.5 2.6 2.2 1 1 1 2 2 2 0 Casein kinase substrate phosphoprotein PP28 DUF4175 PF13779.6 CCC69695.1 - 3.2 5.6 13.4 3.6 5.4 13.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pyr_redox_2 PF07992.14 CCC69696.1 - 6.1e-51 173.4 0.0 8.2e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCC69696.1 - 4.2e-11 43.2 0.0 6.3e-10 39.5 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCC69696.1 - 0.00032 20.1 0.1 1.5 8.0 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CCC69696.1 - 0.0025 17.8 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 2 FAD-NAD(P)-binding zf-C3HC4_5 PF17121.5 CCC69696.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF4795 PF16043.5 CCC69697.1 - 0.041 13.5 5.1 0.062 12.9 5.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) FliJ PF02050.16 CCC69697.1 - 0.069 13.4 6.5 2.1 8.6 6.5 2.4 1 1 0 2 2 2 0 Flagellar FliJ protein 7kD_DNA_binding PF02294.18 CCC69697.1 - 0.14 12.2 0.9 0.36 10.9 0.4 1.9 2 0 0 2 2 2 0 7kD DNA-binding domain TMF_DNA_bd PF12329.8 CCC69697.1 - 3.7 7.6 10.3 26 4.9 0.0 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Ribosomal_S9 PF00380.19 CCC69698.1 - 1.2e-32 112.9 0.2 1.4e-32 112.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L13e PF01294.18 CCC69699.1 - 2.3e-67 226.3 4.1 3.6e-67 225.7 4.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L13e Ribosomal_60s PF00428.19 CCC69700.1 - 3e-21 75.8 8.4 3.6e-21 75.5 8.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Dimer_Tnp_hAT PF05699.14 CCC69702.1 - 1.3e-05 24.9 2.1 2.9e-05 23.8 0.1 2.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CCC69702.1 - 0.74 9.9 9.9 0.081 13.0 5.2 2.0 2 0 0 2 2 2 0 BED zinc finger ADH_N PF08240.12 CCC69703.1 - 1.6e-27 95.6 5.7 2.8e-27 94.7 5.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCC69703.1 - 2.4e-17 63.1 0.0 3.9e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCC69703.1 - 3.4e-06 28.1 0.0 5.2e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 CCC69703.1 - 1e-05 25.0 0.4 1.7e-05 24.3 0.4 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCC69703.1 - 0.0022 17.3 0.0 0.0034 16.7 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 CCC69703.1 - 0.12 12.9 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pkinase PF00069.25 CCC69704.1 - 3.2e-62 210.3 0.0 5.1e-62 209.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69704.1 - 3.7e-21 75.6 0.0 6.5e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 CCC69704.1 - 8.9e-05 22.2 0.2 0.00016 21.4 0.2 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 CCC69704.1 - 0.0081 16.1 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 CCC69704.1 - 0.0098 14.9 0.6 0.017 14.1 0.6 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 CCC69704.1 - 0.033 13.0 0.6 0.051 12.3 0.6 1.4 1 1 0 1 1 1 0 Fungal protein kinase Arf PF00025.21 CCC69705.1 - 1.9e-42 144.7 0.1 2.2e-42 144.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 CCC69705.1 - 2.4e-12 46.7 2.7 8.5e-08 31.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 CCC69705.1 - 4.3e-10 39.4 0.0 5e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC69705.1 - 9.5e-10 38.7 0.0 1.5e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 CCC69705.1 - 3.3e-08 33.6 0.0 4.7e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CCC69705.1 - 4e-08 32.9 0.0 4.9e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 CCC69705.1 - 5.4e-07 29.7 0.1 0.011 15.6 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CCC69705.1 - 1.4e-05 24.6 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CCC69705.1 - 0.0012 18.4 0.4 0.02 14.4 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 CCC69705.1 - 0.0056 16.2 0.0 1.9 8.0 0.0 2.3 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 CCC69705.1 - 0.011 15.5 0.1 0.23 11.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 CCC69705.1 - 0.018 14.7 0.0 5.6 6.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 CCC69705.1 - 0.082 13.3 0.0 0.5 10.7 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 CCC69705.1 - 0.13 12.2 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DRMBL PF07522.14 CCC69706.1 - 1.9e-26 92.4 0.0 5.9e-26 90.8 0.0 1.8 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 CCC69706.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain GATA PF00320.27 CCC69707.1 - 9.8e-16 57.1 4.4 1.8e-15 56.2 4.4 1.4 1 0 0 1 1 1 1 GATA zinc finger Erv26 PF04148.13 CCC69708.1 - 1.8e-83 279.4 3.8 2e-83 279.2 3.8 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 DUF996 PF06195.13 CCC69708.1 - 1.2 9.4 8.0 0.21 11.9 2.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF996) Oxidored_FMN PF00724.20 CCC69709.1 - 8.7e-137 456.0 0.0 1e-136 455.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF5335 PF17269.2 CCC69709.1 - 0.1 12.4 0.1 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Fungal_trans PF04082.18 CCC69710.1 - 6.7e-23 81.1 1.2 3.3e-22 78.8 1.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC69710.1 - 3.8e-07 30.1 12.3 6.2e-07 29.4 12.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FliD_C PF07195.12 CCC69710.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FMO-like PF00743.19 CCC69711.1 - 1.5e-41 142.5 0.2 5.9e-33 114.1 0.1 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 CCC69711.1 - 7.9e-16 58.2 0.1 5e-15 55.6 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 CCC69711.1 - 6.1e-15 55.2 0.0 1.6e-14 53.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CCC69711.1 - 5e-14 52.6 0.0 8.5e-12 45.3 0.0 3.5 3 1 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 CCC69711.1 - 3.9e-10 39.4 0.8 3e-08 33.2 0.1 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 CCC69711.1 - 7e-08 32.4 0.0 0.003 17.2 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCC69711.1 - 1.6e-07 31.4 0.0 4.2e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CCC69711.1 - 6.1e-06 26.7 0.5 1.2 9.8 0.0 3.8 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCC69711.1 - 1.8e-05 24.1 0.1 0.0032 16.7 0.0 2.4 2 0 0 2 2 2 1 Thi4 family MCRA PF06100.11 CCC69711.1 - 0.0014 17.5 1.0 0.14 11.0 0.4 2.4 3 0 0 3 3 3 1 MCRA family Amino_oxidase PF01593.24 CCC69711.1 - 0.0032 16.8 0.0 1.1 8.5 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase HI0933_like PF03486.14 CCC69711.1 - 0.015 14.0 0.1 0.46 9.1 0.1 2.7 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.12 CCC69711.1 - 0.084 11.9 0.0 7.6 5.5 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.19 CCC69711.1 - 0.098 11.9 0.0 2.1 7.5 0.0 2.6 3 0 0 3 3 3 0 FAD binding domain IlvN PF07991.12 CCC69711.1 - 0.11 12.0 0.1 6.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 CCC69711.1 - 0.14 12.6 0.0 8 7.0 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 CCC69711.1 - 0.15 12.1 0.0 20 5.1 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ctr PF04145.15 CCC69712.1 - 3e-25 89.6 15.9 3.9e-23 82.7 15.9 2.1 1 1 0 1 1 1 1 Ctr copper transporter family DUF443 PF04276.12 CCC69712.1 - 0.067 13.0 1.2 0.082 12.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) Enolase_C PF00113.22 CCC69713.1 - 2.2e-150 499.9 0.0 3.2e-150 499.4 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 CCC69713.1 - 5.4e-57 191.6 0.4 9.3e-57 190.8 0.4 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 CCC69713.1 - 1.2e-06 28.2 0.0 2.7e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 CCC69713.1 - 0.026 13.7 0.8 0.1 11.7 0.1 2.0 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus GCP_N_terminal PF17681.1 CCC69714.1 - 1.4e-35 123.4 1.1 1.4e-35 123.4 1.1 1.7 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 CCC69714.1 - 3.6e-15 56.2 5.1 3.6e-15 56.2 5.1 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component C-terminal Proteasome PF00227.26 CCC69715.1 - 2.7e-53 180.3 0.0 3.5e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCC69715.1 - 2.6e-12 46.2 0.0 5.3e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ThiF PF00899.21 CCC69716.1 - 1.1e-48 165.7 0.0 1.8e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family ATG7_N PF16420.5 CCC69716.1 - 2.9e-47 161.8 4.1 6.8e-47 160.6 4.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus Shikimate_DH PF01488.20 CCC69716.1 - 0.0034 17.4 0.0 0.048 13.7 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 CCC69716.1 - 0.024 14.0 0.0 2.1 7.7 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NMD3 PF04981.13 CCC69717.1 - 3.5e-84 282.1 1.5 5.5e-84 281.4 1.5 1.3 1 0 0 1 1 1 1 NMD3 family DZR PF12773.7 CCC69717.1 - 0.2 11.7 7.3 3.9 7.6 5.2 2.7 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 CCC69717.1 - 0.36 10.9 6.7 5.8 7.0 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA NinF PF05810.12 CCC69717.1 - 1.6 8.7 4.2 7.2 6.6 0.8 3.1 3 0 0 3 3 3 0 NinF protein GTP1_OBG PF01018.22 CCC69718.1 - 2.1e-35 121.6 0.4 1.4e-25 89.7 0.4 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 CCC69718.1 - 2.2e-20 72.9 0.0 3.8e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCC69718.1 - 5.2e-13 48.8 0.0 7.7e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.21 CCC69718.1 - 0.00022 20.7 0.0 0.00052 19.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 CCC69718.1 - 0.0016 18.1 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CCC69718.1 - 0.027 13.9 0.0 0.051 13.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 CCC69718.1 - 0.044 13.7 0.2 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1_Xtn PF16897.5 CCC69718.1 - 0.062 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain GTP_EFTU PF00009.27 CCC69718.1 - 0.13 11.8 0.0 14 5.1 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain THP2 PF09432.10 CCC69719.1 - 2e-55 186.3 2.2 2e-55 186.3 2.2 1.8 2 0 0 2 2 2 1 Tho complex subunit THP2 Hist_deacetyl PF00850.19 CCC69719.1 - 0.29 10.6 1.4 0.61 9.5 1.4 1.8 1 1 0 1 1 1 0 Histone deacetylase domain DUF5344 PF17279.2 CCC69719.1 - 6.4 7.4 12.8 4.1 8.0 2.1 4.1 2 2 2 4 4 4 0 Family of unknown function (DUF5344) ANAPC8 PF04049.13 CCC69720.1 - 2.8e-42 144.1 2.4 8.5e-42 142.5 2.4 1.9 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_8 PF13181.6 CCC69720.1 - 6.4e-22 75.9 24.2 2.6e-05 24.1 0.0 8.7 9 1 0 9 9 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 CCC69720.1 - 1.7e-21 75.1 21.2 4.5e-06 26.3 0.0 8.0 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 CCC69720.1 - 4.5e-17 60.7 19.0 3.7e-05 23.5 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 CCC69720.1 - 1.1e-14 53.9 0.2 0.027 15.3 0.0 6.4 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCC69720.1 - 1.4e-09 37.5 8.2 1.7e-06 27.6 0.0 4.6 3 2 2 5 5 5 2 TPR repeat TPR_16 PF13432.6 CCC69720.1 - 1.1e-08 35.6 0.0 0.00024 21.7 0.0 4.2 4 1 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCC69720.1 - 5.4e-08 32.3 6.7 0.051 13.6 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC69720.1 - 8.3e-08 32.4 17.4 0.0064 16.7 0.1 6.3 2 1 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CCC69720.1 - 1.4e-07 31.7 5.8 0.00011 22.5 0.1 4.9 3 1 4 7 7 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 CCC69720.1 - 7e-07 29.5 12.8 0.76 10.6 0.0 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat RPN7 PF10602.9 CCC69720.1 - 5.6e-06 26.2 0.7 2.5e-05 24.0 0.7 2.1 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_9 PF13371.6 CCC69720.1 - 1.7e-05 24.9 0.0 0.41 10.8 0.0 3.9 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CCC69720.1 - 5e-05 22.6 0.9 0.13 11.4 0.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat ChAPs PF09295.10 CCC69720.1 - 7.2e-05 22.0 1.5 0.02 13.9 0.1 2.4 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.6 CCC69720.1 - 0.00029 20.6 8.3 2.9 7.9 0.1 5.8 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCC69720.1 - 0.0016 18.9 3.3 1 9.9 0.3 4.9 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCC69720.1 - 0.0037 17.5 17.0 0.74 10.3 0.8 6.0 7 0 0 7 7 4 2 Tetratricopeptide repeat BTAD PF03704.17 CCC69720.1 - 0.025 15.0 0.0 0.08 13.4 0.0 1.8 1 1 0 1 1 1 0 Bacterial transcriptional activator domain NSF PF02071.20 CCC69720.1 - 0.067 13.9 0.4 93 4.5 0.0 4.9 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat DUF3856 PF12968.7 CCC69720.1 - 0.084 12.9 0.2 3.7 7.6 0.0 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) DUF1765 PF08578.10 CCC69720.1 - 0.21 12.0 5.7 4.8 7.7 1.5 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1765) PROCN PF08083.11 CCC69721.1 - 2.8e-226 750.9 10.0 4.3e-226 750.3 10.0 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 CCC69721.1 - 6e-123 408.9 1.4 1.2e-122 407.9 1.4 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 CCC69721.1 - 3.4e-84 280.6 1.4 3.4e-84 280.6 1.4 2.2 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 CCC69721.1 - 1.6e-79 265.1 3.3 3.6e-79 264.0 3.3 1.6 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 CCC69721.1 - 2.6e-69 231.5 0.1 1.3e-68 229.2 0.0 2.2 2 0 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 CCC69721.1 - 1.3e-47 160.1 0.3 4e-47 158.5 0.3 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 CCC69721.1 - 3.8e-47 159.2 0.1 1e-46 157.9 0.1 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 CCC69721.1 - 0.0004 20.3 0.1 0.0017 18.3 0.0 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Endonuclease_NS PF01223.23 CCC69721.1 - 0.044 13.6 2.1 2.9 7.7 0.1 2.7 2 0 0 2 2 2 0 DNA/RNA non-specific endonuclease Dna2 PF08696.11 CCC69723.1 - 6.5e-59 199.2 0.0 1.8e-58 197.7 0.0 1.8 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_12 PF13087.6 CCC69723.1 - 1.2e-49 168.7 1.2 2.5e-49 167.6 1.2 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CCC69723.1 - 2.4e-31 109.5 5.0 3.4e-17 63.1 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.6 CCC69723.1 - 5.1e-13 49.2 0.0 1.1e-12 48.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCC69723.1 - 1.1e-12 48.5 0.1 9e-12 45.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CCC69723.1 - 4.1e-08 33.3 1.0 0.072 12.8 0.0 4.5 3 1 1 4 4 4 3 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.17 CCC69723.1 - 5.4e-07 29.9 0.0 1.7e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF83 PDDEXK_1 PF12705.7 CCC69723.1 - 1.8e-06 28.1 0.0 3.3e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily UvrD-helicase PF00580.21 CCC69723.1 - 5.3e-05 22.9 6.0 7.2e-05 22.4 0.0 2.8 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Csa1 PF06023.12 CCC69723.1 - 0.00023 20.6 0.1 0.00045 19.7 0.1 1.4 1 0 0 1 1 1 1 CRISPR-associated exonuclease Csa1 Helicase_RecD PF05127.14 CCC69723.1 - 0.0014 18.5 0.0 0.004 17.0 0.0 1.8 1 1 0 1 1 1 1 Helicase SRP54 PF00448.22 CCC69723.1 - 0.0016 18.1 0.0 0.0035 17.0 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_16 PF13191.6 CCC69723.1 - 0.0071 16.7 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 CCC69723.1 - 0.012 16.2 0.0 0.064 13.8 0.0 2.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CCC69723.1 - 0.012 14.9 1.6 0.24 10.5 0.0 3.0 3 0 0 3 3 3 0 NB-ARC domain NTPase_1 PF03266.15 CCC69723.1 - 0.033 14.1 0.1 0.12 12.3 0.1 2.0 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.6 CCC69723.1 - 0.038 14.4 0.3 0.42 11.0 0.1 2.8 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 CCC69723.1 - 0.04 13.5 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CCC69723.1 - 0.045 13.5 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.17 CCC69723.1 - 0.057 13.2 0.1 0.19 11.5 0.1 1.9 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein ATPase_2 PF01637.18 CCC69723.1 - 0.066 13.1 3.4 0.3 11.0 0.0 3.0 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 CCC69723.1 - 0.068 12.2 0.0 0.13 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 CCC69723.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 CCC69723.1 - 0.089 13.3 1.0 0.29 11.6 0.0 2.4 2 0 0 2 2 2 0 ABC transporter UvrD_C_2 PF13538.6 CCC69723.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain MobB PF03205.14 CCC69723.1 - 0.2 11.6 1.5 0.22 11.4 0.1 1.8 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 CCC69723.1 - 0.28 10.9 2.2 1.2 8.8 2.2 2.0 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 CCC69723.1 - 4.9 7.1 9.7 0.4 10.6 0.1 3.3 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit Glucosamine_iso PF01182.20 CCC69724.1 - 3.9e-62 210.1 0.0 4.7e-62 209.8 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DDE_1 PF03184.19 CCC69725.1 - 0.0019 17.9 0.1 0.0057 16.3 0.0 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease TcpS PF17456.2 CCC69725.1 - 0.0042 17.2 0.9 0.2 11.7 0.1 3.0 2 0 0 2 2 2 1 Toxin-coregulated pilus protein S NUMOD1 PF07453.13 CCC69725.1 - 0.025 14.8 0.1 2 8.8 0.0 3.8 4 0 0 4 4 4 0 NUMOD1 domain HTH_23 PF13384.6 CCC69725.1 - 0.073 12.9 0.2 28 4.6 0.0 3.3 3 0 0 3 3 3 0 Homeodomain-like domain MPC PF03650.13 CCC69726.1 - 2.4e-46 156.4 0.1 2.8e-46 156.2 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers ANTH PF07651.16 CCC69727.1 - 5.4e-65 219.1 0.5 5.4e-65 219.1 0.5 1.9 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.20 CCC69727.1 - 7.1e-06 26.1 0.0 2.2e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 ENTH domain TBPIP PF07106.13 CCC69727.1 - 0.045 13.7 4.2 11 6.0 0.4 4.4 4 0 0 4 4 4 0 TBPIP/Hop2 winged helix domain BK_channel_a PF03493.18 CCC69728.1 - 0.083 13.1 0.7 0.24 11.6 0.2 2.2 2 1 0 2 2 2 0 Calcium-activated BK potassium channel alpha subunit TagA PF12561.8 CCC69728.1 - 0.11 12.9 0.4 0.24 11.8 0.4 1.7 1 1 0 1 1 1 0 ToxR activated gene A lipoprotein domain zf-C4H2 PF10146.9 CCC69728.1 - 1 9.6 7.3 0.12 12.6 2.5 1.8 1 1 0 2 2 2 0 Zinc finger-containing protein TDA11 PF17084.5 CCC69729.1 - 5.1e-49 167.5 31.7 4.1e-26 92.0 8.0 2.9 1 1 1 2 2 2 2 Topoisomerase I damage affected protein 11 CENP-Q PF13094.6 CCC69729.1 - 0.00026 21.2 4.4 0.00026 21.2 4.4 1.9 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit IL32 PF15225.6 CCC69729.1 - 0.096 13.1 0.0 0.26 11.7 0.0 1.7 1 0 0 1 1 1 0 Interleukin 32 DUF3597 PF12200.8 CCC69729.1 - 4.3 7.9 8.1 0.26 11.8 0.6 2.7 2 1 2 4 4 4 0 Domain of unknown function (DUF3597) S-antigen PF05756.11 CCC69729.1 - 6.7 7.2 6.8 3.9 7.9 3.4 2.3 2 0 0 2 2 2 0 S-antigen protein DUF2951 PF11166.8 CCC69729.1 - 9.8 6.5 9.2 21 5.4 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) RTT107_BRCT_6 PF16771.5 CCC69732.1 - 2.4e-39 134.0 4.4 2.4e-39 134.0 4.4 3.8 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain RTT107_BRCT_5 PF16770.5 CCC69732.1 - 7.8e-24 83.5 7.7 3.7e-23 81.3 0.0 4.6 6 0 0 6 6 6 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 CCC69732.1 - 1.2e-18 66.7 1.6 7.5e-14 51.4 0.1 3.7 4 0 0 4 4 4 2 twin BRCT domain BRCT PF00533.26 CCC69732.1 - 2.5e-18 66.2 11.8 7.5e-07 29.4 0.0 5.7 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCC69732.1 - 2.7e-15 56.5 2.1 0.00036 20.9 0.1 4.7 3 1 1 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain Ice_nucleation PF00818.17 CCC69733.1 - 0.25 11.5 0.5 0.48 10.6 0.5 1.5 1 0 0 1 1 1 0 Ice nucleation protein repeat Spo12 PF05032.12 CCC69734.1 - 4.4e-17 61.7 3.7 4.4e-17 61.7 3.7 2.3 2 0 0 2 2 2 1 Spo12 family Pex24p PF06398.11 CCC69736.1 - 9.5e-67 225.5 1.0 1.4e-66 225.0 1.0 1.3 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin SKG6 PF08693.10 CCC69737.1 - 3.6e-15 55.1 5.3 8.4e-15 53.9 5.3 1.7 1 0 0 1 1 1 1 Transmembrane alpha-helix domain TMEM154 PF15102.6 CCC69737.1 - 0.0015 18.4 2.1 0.0025 17.7 0.0 2.6 2 0 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.6 CCC69737.1 - 0.013 15.3 0.0 0.013 15.3 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 CCC69737.1 - 0.57 11.1 2.6 0.85 10.5 0.0 2.7 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Ribosomal_S4 PF00163.19 CCC69738.1 - 1e-12 48.8 2.0 1.3e-12 48.4 1.5 1.4 1 1 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.25 CCC69738.1 - 1.7e-12 46.9 0.0 1.7e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 S4 domain Herpes_LAMP2 PF06126.11 CCC69738.1 - 0.0068 15.1 0.1 0.0083 14.8 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus Latent membrane protein 2 Pox_A_type_inc PF04508.12 CCC69738.1 - 0.082 12.8 2.7 1 9.3 0.6 2.8 2 1 0 2 2 2 0 Viral A-type inclusion protein repeat Ribosomal_L6 PF00347.23 CCC69739.1 - 3.2e-21 75.8 0.2 5.1e-10 39.9 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L6 CRM1_C PF08767.11 CCC69740.1 - 5e-71 239.5 15.0 5e-71 239.5 15.0 2.4 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 CCC69740.1 - 1.3e-29 103.2 6.6 1.3e-29 103.2 6.6 4.0 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 CCC69740.1 - 1e-11 44.6 1.4 3.8e-11 42.7 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain CRM1_repeat_2 PF18784.1 CCC69740.1 - 7e-11 41.6 1.2 2.9e-10 39.6 1.2 2.2 1 0 0 1 1 1 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 CCC69740.1 - 8.9e-07 28.9 0.1 3.4e-06 27.1 0.1 2.1 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 AA_permease_2 PF13520.6 CCC69741.1 - 7.3e-68 229.3 42.7 8.8e-68 229.1 42.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCC69741.1 - 2.5e-20 72.5 29.4 2.5e-20 72.5 29.4 1.9 2 0 0 2 2 2 1 Amino acid permease RE_SinI PF09570.10 CCC69741.1 - 0.74 9.0 2.6 0.82 8.9 0.2 2.0 2 0 0 2 2 2 0 SinI restriction endonuclease DPM2 PF07297.12 CCC69743.1 - 6.1e-08 32.9 10.1 7.1e-08 32.7 10.1 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF4229 PF14012.6 CCC69743.1 - 7.5 6.7 10.3 1.5e+02 2.5 10.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4229) LapA_dom PF06305.11 CCC69743.1 - 8.1 6.3 10.9 0.12 12.2 4.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Ribosomal_S2 PF00318.20 CCC69744.1 - 1.1e-25 90.1 3.1 7.1e-14 51.5 0.0 2.6 2 1 1 3 3 3 2 Ribosomal protein S2 40S_SA_C PF16122.5 CCC69744.1 - 0.011 17.1 12.8 0.025 16.0 12.8 1.6 1 0 0 1 1 1 0 40S ribosomal protein SA C-terminus Ferric_reduct PF01794.19 CCC69745.1 - 4.1e-19 68.9 11.3 4.1e-19 68.9 11.3 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 CCC69745.1 - 0.0027 17.8 0.0 0.022 14.9 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 CCC69745.1 - 0.0066 16.5 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Glyco_hydro_16 PF00722.21 CCC69746.1 - 5.2e-20 71.7 4.4 1.1e-19 70.6 4.4 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.6 CCC69746.1 - 0.00067 19.8 1.1 0.00067 19.8 1.1 2.2 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily TPP_enzyme_N PF02776.18 CCC69747.1 - 3.5e-32 111.4 0.0 5.7e-32 110.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCC69747.1 - 6.1e-26 90.8 0.0 2.8e-25 88.6 0.0 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCC69747.1 - 2e-12 47.2 0.0 3.7e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain HEAT PF02985.22 CCC69748.1 - 0.0088 16.2 0.5 2.1 8.8 0.0 4.6 6 0 0 6 6 6 1 HEAT repeat Cnd1 PF12717.7 CCC69748.1 - 0.018 15.1 1.7 7.8 6.5 0.0 3.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 CcdA PF07362.12 CCC69748.1 - 0.024 15.1 1.9 0.024 15.1 1.9 3.2 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Vac14_Fab1_bd PF12755.7 CCC69748.1 - 0.055 14.1 0.0 4.2 8.0 0.0 3.2 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region Aldolase_II PF00596.21 CCC69749.1 - 6.2e-43 146.9 0.0 8.2e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1858 PF08984.11 CCC69749.1 - 0.007 16.5 0.0 0.96 9.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF1858) LSM PF01423.22 CCC69750.1 - 2.2e-10 40.1 0.4 6.1e-10 38.6 0.4 1.8 1 0 0 1 1 1 1 LSM domain Mer2 PF09074.10 CCC69751.1 - 1.9e-68 230.1 20.3 3e-68 229.5 20.3 1.3 1 0 0 1 1 1 1 Mer2 RsbRD_N PF14361.6 CCC69751.1 - 0.049 14.3 1.6 0.21 12.3 0.2 2.2 2 0 0 2 2 2 0 RsbT co-antagonist protein rsbRD N-terminal domain RNase_Zc3h12a_2 PF14626.6 CCC69751.1 - 0.091 13.0 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain CHDCT2 PF08074.11 CCC69751.1 - 0.53 10.4 7.7 0.52 10.5 5.3 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain ATG16 PF08614.11 CCC69751.1 - 1.6 8.9 11.4 0.68 10.1 5.0 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Acyl_CoA_thio PF02551.15 CCC69752.1 - 1.6e-44 151.0 2.4 2.7e-32 111.4 0.6 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.6 CCC69752.1 - 1.5e-37 130.2 0.0 2.1e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Rotamase PF00639.21 CCC69753.1 - 8.2e-28 97.2 0.1 1.1e-27 96.8 0.1 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 CCC69753.1 - 3.4e-21 75.9 0.0 4.7e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.26 CCC69753.1 - 2.7e-08 33.7 2.2 4.3e-08 33.1 2.2 1.3 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.6 CCC69753.1 - 3.9e-08 34.1 0.0 7.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain HEPN_AbiV PF18728.1 CCC69753.1 - 0.06 13.5 1.4 0.089 12.9 1.4 1.2 1 0 0 1 1 1 0 AbiV X8 PF07983.13 CCC69753.1 - 0.18 12.5 0.0 0.3 11.8 0.0 1.3 1 0 0 1 1 1 0 X8 domain CTP_transf_like PF01467.26 CCC69754.1 - 1.4e-34 119.3 0.1 4.9e-34 117.6 0.0 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like Trefoil PF00088.18 CCC69754.1 - 0.07 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Trefoil (P-type) domain GvpL_GvpF PF06386.11 CCC69754.1 - 0.4 10.6 0.0 0.4 10.6 0.0 2.3 2 0 0 2 2 2 0 Gas vesicle synthesis protein GvpL/GvpF PTPRCAP PF15713.5 CCC69754.1 - 0.46 10.8 20.7 0.18 12.1 5.0 2.4 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated DUF1682 PF07946.14 CCC69754.1 - 8.4 5.5 20.2 4.3 6.4 17.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1682) RR_TM4-6 PF06459.12 CCC69754.1 - 8.4 6.1 24.1 5.8 6.7 11.6 2.2 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 ILVD_EDD PF00920.21 CCC69755.1 - 2.1e-209 696.5 0.4 2.4e-209 696.3 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family Thi4 PF01946.17 CCC69756.1 - 2.8e-105 350.8 0.3 3.3e-105 350.5 0.3 1.0 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 CCC69756.1 - 2.6e-06 27.3 1.8 5.4e-06 26.2 0.7 1.8 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCC69756.1 - 3.4e-06 27.2 0.1 1.1e-05 25.6 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CCC69756.1 - 5e-05 22.6 2.0 0.00056 19.1 0.2 2.5 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 CCC69756.1 - 0.00013 21.3 0.1 0.00018 20.9 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 CCC69756.1 - 0.00028 20.1 0.1 0.00034 19.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 CCC69756.1 - 0.00041 20.4 0.2 0.00091 19.2 0.1 1.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 CCC69756.1 - 0.0018 17.7 0.1 0.0028 17.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 CCC69756.1 - 0.0078 15.0 0.2 0.0078 15.0 0.2 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 CCC69756.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCC69756.1 - 0.021 13.9 0.1 0.064 12.3 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CCC69756.1 - 0.11 11.7 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.14 CCC69756.1 - 0.13 11.1 0.1 0.18 10.6 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DUF3533 PF12051.8 CCC69757.1 - 9.7e-117 390.1 20.8 1.2e-116 389.7 20.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) SUI1 PF01253.22 CCC69758.1 - 1.4e-21 76.8 1.0 3e-21 75.7 1.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF3922 PF13059.6 CCC69758.1 - 0.029 14.8 1.6 0.052 14.0 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3992) IF-2 PF11987.8 CCC69758.1 - 0.1 12.7 0.7 0.1 12.7 0.7 1.9 2 1 0 2 2 2 0 Translation-initiation factor 2 RNase_PH PF01138.21 CCC69759.1 - 2.9e-26 92.5 0.0 4.2e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCC69759.1 - 2.1e-05 24.5 0.1 5.2e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mannosyl_trans PF05007.13 CCC69760.1 - 4e-87 292.4 25.5 5.7e-87 291.9 25.5 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 CCC69760.1 - 7.3e-08 31.9 29.6 3e-07 29.9 29.6 1.9 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 CCC69760.1 - 8.7e-08 32.2 5.0 8.7e-08 32.2 5.0 1.9 1 1 0 2 2 2 1 Glycosyltransferase family 87 DUF5572 PF17733.1 CCC69761.1 - 4.8e-13 48.7 0.1 7.4e-13 48.1 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5572) DUF1688 PF07958.11 CCC69762.1 - 0.068 11.9 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1688) CSN4_RPN5_eIF3a PF18420.1 CCC69762.1 - 0.42 10.8 3.2 0.71 10.1 0.3 2.3 2 0 0 2 2 2 0 CSN4/RPN5/eIF3a helix turn helix domain SPC12 PF06645.13 CCC69763.1 - 1.4e-26 92.3 1.2 1.7e-26 92.1 1.2 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) ATP-sulfurylase PF01747.17 CCC69764.1 - 4.8e-86 287.6 0.0 6.2e-86 287.2 0.0 1.1 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 CCC69764.1 - 4.1e-49 166.3 0.0 6.3e-49 165.7 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain CTP_transf_like PF01467.26 CCC69764.1 - 0.062 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase-like Gp_dh_C PF02800.20 CCC69765.1 - 1e-72 242.9 0.5 2e-72 242.0 0.3 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CCC69765.1 - 1.6e-39 134.3 0.1 4.1e-39 133.0 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 CCC69765.1 - 0.027 14.6 0.7 0.078 13.1 0.1 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Memo PF01875.17 CCC69766.1 - 1.7e-91 306.1 0.6 2e-91 305.9 0.6 1.0 1 0 0 1 1 1 1 Memo-like protein EIF_2_alpha PF07541.12 CCC69767.1 - 5.4e-38 129.7 1.1 7.6e-38 129.2 0.3 1.7 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 CCC69767.1 - 1.9e-14 53.8 1.0 4.9e-14 52.4 1.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain Troponin PF00992.20 CCC69767.1 - 0.0049 17.2 0.9 0.012 15.9 0.9 1.6 1 0 0 1 1 1 1 Troponin Treacle PF03546.14 CCC69767.1 - 0.0086 15.0 0.6 0.01 14.7 0.6 1.1 1 0 0 1 1 1 1 Treacher Collins syndrome protein Treacle AAA_23 PF13476.6 CCC69767.1 - 0.074 13.5 1.6 0.14 12.6 1.6 1.5 1 1 0 1 1 1 0 AAA domain YbaB_DNA_bd PF02575.16 CCC69767.1 - 0.93 9.8 5.1 6.8 7.0 0.2 2.8 3 0 0 3 3 3 0 YbaB/EbfC DNA-binding family AA_permease PF00324.21 CCC69768.1 - 1.2e-137 459.4 33.4 1.5e-137 459.1 33.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC69768.1 - 2.1e-37 129.0 34.2 2.6e-37 128.7 34.2 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_16 PF00722.21 CCC69770.1 - 2.3e-45 154.2 2.0 2.3e-45 154.2 2.0 2.4 3 1 1 4 4 4 1 Glycosyl hydrolases family 16 Plasmodium_Vir PF05795.11 CCC69770.1 - 7.7 5.8 10.5 19 4.5 10.4 1.6 1 1 1 2 2 2 0 Plasmodium vivax Vir protein RNA_pol_Rpb4 PF03874.16 CCC69771.1 - 1.8e-32 112.3 7.2 2.4e-32 111.9 7.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 VTC PF09359.10 CCC69772.1 - 4.9e-100 334.5 0.6 6.8e-100 334.0 0.0 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.19 CCC69772.1 - 2.5e-10 40.8 14.8 4.3e-06 26.9 0.6 3.6 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 CCC69772.1 - 1.3e-09 38.3 5.0 1.3e-09 38.3 5.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) ApoLp-III PF07464.11 CCC69772.1 - 0.071 13.2 0.9 0.18 11.9 0.9 1.7 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) HIP1_clath_bdg PF16515.5 CCC69772.1 - 1 10.0 3.0 3.6 8.2 0.1 2.5 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Mad3_BUB1_I PF08311.12 CCC69773.1 - 1.1e-37 128.8 1.4 2.2e-37 127.8 1.4 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.11 CCC69773.1 - 1.3e-24 86.1 2.1 3e-23 81.8 0.2 2.9 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Mad3_BUB1_I_2 PF17014.5 CCC69773.1 - 0.0023 18.1 2.3 0.0046 17.1 2.3 1.5 1 0 0 1 1 1 1 Putative Mad3/BUB1 like region 1 protein Sad1_UNC PF07738.13 CCC69775.1 - 8.9e-06 25.8 2.3 0.085 12.9 0.2 3.0 2 1 1 3 3 3 2 Sad1 / UNC-like C-terminal SBDS_C PF09377.10 CCC69775.1 - 0.17 11.9 1.6 0.33 11.0 0.1 2.3 3 0 0 3 3 3 0 SBDS protein C-terminal domain Plasmid_RAQPRD PF09686.10 CCC69775.1 - 0.23 11.7 2.1 0.47 10.7 0.5 2.3 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) SH3_1 PF00018.28 CCC69776.1 - 7.2e-10 38.3 0.7 7.2e-10 38.3 0.7 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.17 CCC69776.1 - 3.9e-09 36.1 0.0 9.6e-09 34.8 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 CCC69776.1 - 6.9e-07 29.0 0.3 1.5e-06 28.0 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain TFIIA PF03153.13 CCC69776.1 - 1.3 8.9 35.2 1.5 8.7 3.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit eIF3_subunit PF08597.10 CCC69778.1 - 7.8 6.3 20.6 8.6 6.2 20.6 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit DNA_pol_E_B PF04042.16 CCC69779.1 - 8.5e-44 149.4 0.0 1.3e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 CCC69779.1 - 3e-36 124.4 0.0 4.8e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain HSP20 PF00011.21 CCC69780.1 - 1.7e-17 63.4 0.3 2.2e-17 63.0 0.3 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 CCC69780.1 - 1.8e-05 24.2 0.0 5.1e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Ribonuc_red_sm PF00268.21 CCC69781.1 - 7.6e-117 389.7 2.3 1.1e-116 389.2 2.3 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 CCC69781.1 - 0.16 12.8 0.0 0.34 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) zf-RING_2 PF13639.6 CCC69782.1 - 3.2e-11 43.4 6.6 5.3e-11 42.7 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CCC69782.1 - 2e-07 30.9 4.5 3.3e-07 30.2 4.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 CCC69782.1 - 3.5e-07 30.0 3.8 5.8e-07 29.3 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CCC69782.1 - 1.2e-06 28.6 5.6 2.4e-06 27.7 5.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 CCC69782.1 - 3.2e-05 23.7 7.2 7.5e-05 22.5 7.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCC69782.1 - 6.1e-05 22.8 6.5 0.00014 21.6 6.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC69782.1 - 0.00022 21.2 3.1 0.00048 20.1 3.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 CCC69782.1 - 0.00023 20.9 4.6 0.00048 19.9 4.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 CCC69782.1 - 0.015 14.9 2.5 0.031 13.9 2.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 CCC69782.1 - 0.025 14.2 1.4 0.025 14.2 1.4 1.9 2 0 0 2 2 2 0 P-11 zinc finger zf-ANAPC11 PF12861.7 CCC69782.1 - 0.027 14.5 0.8 0.067 13.3 0.8 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 CCC69782.1 - 0.084 12.7 3.1 0.23 11.3 3.1 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 CCC69782.1 - 0.25 11.5 4.8 0.79 10.0 4.8 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_10 PF16685.5 CCC69782.1 - 0.54 10.4 3.8 1.1 9.4 3.8 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 RINGv PF12906.7 CCC69782.1 - 0.67 10.1 6.4 1.4 9.1 6.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 CCC69782.1 - 1.6 8.9 6.5 22 5.3 6.7 2.4 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CCC69782.1 - 1.8 8.4 8.3 0.095 12.5 2.6 1.9 2 0 0 2 2 2 0 RING-like zinc finger Histone PF00125.24 CCC69783.1 - 2.7e-17 63.3 0.0 3.4e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 CCC69783.1 - 1.3e-13 50.4 0.3 2.2e-13 49.7 0.3 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 CCC69783.1 - 0.00013 22.1 0.0 0.00019 21.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PLA2_B PF01735.18 CCC69784.1 - 1.4e-221 736.2 0.4 2e-221 735.7 0.4 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 CCC69784.1 - 0.064 13.5 0.8 0.13 12.5 0.8 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain RTC PF01137.21 CCC69785.1 - 4.3e-45 153.6 0.0 5e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 CCC69785.1 - 1.2e-32 112.4 0.0 2.9e-32 111.3 0.0 1.6 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.24 CCC69786.1 - 2e-21 76.1 0.1 5.2e-21 74.7 0.1 1.8 1 0 0 1 1 1 1 PX domain MMM1 PF10296.9 CCC69787.1 - 6.2e-09 35.3 0.0 1e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 Polyketide_cyc PF03364.20 CCC69788.1 - 6.5e-18 65.2 0.0 8.5e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 CCC69788.1 - 0.00086 19.6 0.0 0.0012 19.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Vpu PF00558.19 CCC69789.1 - 0.36 10.6 2.7 0.93 9.3 2.7 1.7 1 1 0 1 1 1 0 Vpu protein Topoisom_I PF01028.20 CCC69790.1 - 1.4e-98 328.8 2.6 1.4e-98 328.8 2.6 2.8 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 CCC69790.1 - 8e-97 322.9 0.9 8e-97 322.9 0.9 3.7 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 CCC69790.1 - 5.6e-34 115.9 0.9 5.6e-34 115.9 0.9 2.7 2 1 1 3 3 3 1 C-terminal topoisomerase domain Chitin_bind_4 PF00379.23 CCC69790.1 - 0.25 11.9 0.9 0.85 10.2 0.9 1.9 1 0 0 1 1 1 0 Insect cuticle protein Pkinase PF00069.25 CCC69791.1 - 9.8e-75 251.3 0.5 2e-74 250.3 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69791.1 - 8.1e-40 136.7 0.0 1.4e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 CCC69791.1 - 9.2e-26 89.8 0.0 2.4e-13 50.1 0.0 3.0 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 CCC69791.1 - 5.4e-09 35.8 0.0 2.5e-07 30.3 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 CCC69791.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_3 PF08239.11 CCC69791.1 - 0.088 13.1 0.1 0.17 12.2 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Haspin_kinase PF12330.8 CCC69791.1 - 1.5 7.7 6.3 0.17 10.8 1.3 2.0 2 1 0 2 2 2 0 Haspin like kinase domain PDH_E1_M PF17831.1 CCC69792.1 - 0.18 11.3 0.0 0.69 9.4 0.0 1.8 2 0 0 2 2 2 0 Pyruvate dehydrogenase E1 component middle domain RNA_pol_L_2 PF13656.6 CCC69793.1 - 4.5e-25 87.2 0.0 5.9e-25 86.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CCC69793.1 - 9.8e-09 34.5 0.0 1.9e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF5024 PF16427.5 CCC69793.1 - 0.18 12.2 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5024) Sin3a_C PF16879.5 CCC69794.1 - 1.9e-79 267.4 5.4 1.9e-79 267.4 5.4 3.9 5 0 0 5 5 5 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 CCC69794.1 - 2.1e-43 146.4 0.2 7.3e-43 144.6 0.2 2.0 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.21 CCC69794.1 - 1.4e-42 143.6 17.3 4.4e-17 62.0 2.3 4.1 4 0 0 4 4 4 3 Paired amphipathic helix repeat DHHC PF01529.20 CCC69795.1 - 5.8e-31 107.4 9.0 5.8e-31 107.4 9.0 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase SNAP-25 PF00835.19 CCC69795.1 - 0.11 12.8 0.5 0.25 11.6 0.5 1.5 1 0 0 1 1 1 0 SNAP-25 family Cyclin PF08613.11 CCC69796.1 - 5e-33 114.8 1.5 1e-32 113.7 1.5 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 CCC69796.1 - 0.011 15.5 0.1 0.02 14.6 0.1 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain Alg6_Alg8 PF03155.15 CCC69797.1 - 2.2e-148 495.2 29.3 2.7e-148 495.0 29.3 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Pirin PF02678.16 CCC69798.1 - 4.7e-26 90.9 0.7 2.6e-25 88.5 0.3 2.0 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 CCC69798.1 - 1.5e-16 60.6 0.0 6.9e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 CCC69798.1 - 9.5e-05 22.0 0.3 0.00042 20.0 0.3 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 CCC69798.1 - 0.0035 17.0 0.2 0.72 9.6 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF861) Kelch_3 PF13415.6 CCC69800.1 - 4.6e-31 106.5 2.3 1e-09 38.4 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 CCC69800.1 - 2.1e-30 104.5 5.9 8.5e-06 25.7 0.0 6.8 6 1 0 6 6 6 6 Galactose oxidase, central domain DUF4110 PF13422.6 CCC69800.1 - 1.5e-24 85.9 0.0 1.5e-24 85.9 0.0 4.8 4 1 0 4 4 2 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.6 CCC69800.1 - 5.9e-19 67.6 9.8 7.7e-06 26.0 0.4 5.6 4 1 1 5 5 5 5 Kelch motif Kelch_5 PF13854.6 CCC69800.1 - 4.3e-13 48.9 10.0 0.0099 15.9 0.4 6.1 7 1 0 7 7 7 4 Kelch motif Kelch_1 PF01344.25 CCC69800.1 - 7.8e-10 38.2 12.1 0.0048 16.5 0.3 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 CCC69800.1 - 1.4e-07 31.2 17.9 0.013 15.5 0.0 5.7 6 1 0 6 6 6 3 Kelch motif CNDH2_C PF16858.5 CCC69800.1 - 2.4 8.0 31.5 2.8 7.7 6.4 3.2 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Mpp10 PF04006.12 CCC69800.1 - 4.9 5.5 50.9 0.21 10.0 7.3 3.1 3 0 0 3 3 3 0 Mpp10 protein Vfa1 PF08432.10 CCC69800.1 - 4.9 7.4 43.4 1.6 9.0 5.1 3.3 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 Nop25 PF09805.9 CCC69800.1 - 8.2 6.9 45.5 0.28 11.6 8.6 3.3 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) ATP-synt_Eps PF04627.13 CCC69801.1 - 3.6e-15 55.7 1.0 4.6e-15 55.3 1.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain ABC_membrane PF00664.23 CCC69802.1 - 1.7e-50 172.2 7.5 2.4e-50 171.7 7.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CCC69802.1 - 3.4e-35 121.5 0.0 1.1e-34 119.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CCC69802.1 - 1.5e-05 24.6 0.0 0.00098 18.6 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCC69802.1 - 0.0027 17.4 0.0 0.012 15.4 0.0 2.1 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 CCC69802.1 - 0.0034 17.1 0.1 0.15 11.8 0.0 2.9 2 1 1 3 3 3 1 IstB-like ATP binding protein AAA_5 PF07728.14 CCC69802.1 - 0.017 15.2 0.0 0.066 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.9 CCC69802.1 - 0.019 13.8 0.1 0.038 12.8 0.0 1.5 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA PF00004.29 CCC69802.1 - 0.021 15.3 0.0 0.098 13.1 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCC69802.1 - 0.023 15.1 0.0 0.3 11.5 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain ResIII PF04851.15 CCC69802.1 - 0.023 14.7 0.0 1.9 8.5 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 CCC69802.1 - 0.05 14.1 0.5 0.25 11.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 CCC69802.1 - 0.052 13.8 0.1 0.45 10.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 CCC69802.1 - 0.077 12.8 0.0 2.3 8.0 0.0 2.4 1 1 0 1 1 1 0 DEAD/DEAH box helicase KAR9 PF08580.10 CCC69803.1 - 4.4e-51 174.3 16.9 6.5e-51 173.7 16.9 1.1 1 0 0 1 1 1 1 Yeast cortical protein KAR9 RNA_pol_Rpb6 PF01192.22 CCC69803.1 - 0.16 11.9 0.5 0.43 10.5 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb6 PI-PLC-X PF00388.19 CCC69804.1 - 1.5e-50 170.5 0.0 3.5e-50 169.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 CCC69804.1 - 4.6e-37 126.9 1.1 8.9e-37 125.9 0.1 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.11 CCC69804.1 - 3e-07 30.8 1.0 6.6e-07 29.7 1.0 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.32 CCC69804.1 - 0.00018 20.8 0.5 0.0017 17.8 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 CCC69804.1 - 0.0023 18.4 3.1 0.027 14.9 0.3 3.0 2 0 0 2 2 2 1 EF-hand domain pair C2 PF00168.30 CCC69804.1 - 0.0032 17.7 0.0 0.0095 16.2 0.0 1.8 1 0 0 1 1 1 1 C2 domain EF-hand_6 PF13405.6 CCC69804.1 - 0.027 14.4 1.3 0.14 12.1 0.3 2.7 2 0 0 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 CCC69804.1 - 0.06 13.2 1.2 0.15 11.9 1.2 1.8 1 0 0 1 1 1 0 EF hand W_rich_C PF07483.11 CCC69804.1 - 0.089 13.0 0.0 0.32 11.2 0.0 1.9 1 0 0 1 1 1 0 Tryptophan-rich Synechocystis species C-terminal domain RrnaAD PF00398.20 CCC69806.1 - 2.5e-75 253.0 0.0 2.9e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 CCC69806.1 - 4.3e-07 30.5 0.0 1.3e-06 29.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC69806.1 - 2.5e-05 24.8 0.0 8.6e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 CCC69806.1 - 0.00028 20.7 0.0 0.00048 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 CCC69806.1 - 0.00039 19.8 0.0 0.0014 18.0 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 CCC69806.1 - 0.0012 18.8 0.1 0.54 10.1 0.0 2.3 2 0 0 2 2 2 2 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 CCC69806.1 - 0.0056 17.4 0.0 0.013 16.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 CCC69806.1 - 0.0062 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.6 CCC69806.1 - 0.012 15.5 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.17 CCC69806.1 - 0.037 13.7 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MTS PF05175.14 CCC69806.1 - 0.04 13.5 0.0 0.069 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 CCC69806.1 - 0.049 13.0 0.1 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 CCC69806.1 - 0.086 12.8 0.0 4.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain AAA_lid_4 PF17864.1 CCC69806.1 - 0.1 12.4 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 RuvB AAA lid domain DREV PF05219.12 CCC69806.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase AA_permease PF00324.21 CCC69807.1 - 1.8e-122 409.4 42.8 2.2e-122 409.1 42.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC69807.1 - 1e-32 113.5 42.8 1.4e-32 113.1 42.8 1.1 1 0 0 1 1 1 1 Amino acid permease Importin_rep_6 PF18829.1 CCC69808.1 - 1.5e-46 157.0 3.4 1.5e-46 157.0 3.4 4.1 4 0 0 4 4 4 1 Importin repeat 6 Importin_rep_4 PF18808.1 CCC69808.1 - 7.8e-31 106.2 0.5 7.8e-31 106.2 0.5 3.4 4 0 0 4 4 3 1 Importin repeat HEAT_EZ PF13513.6 CCC69808.1 - 2.7e-19 69.3 8.1 7.2e-10 39.2 0.0 8.5 8 2 2 10 10 8 3 HEAT-like repeat Importin_rep_5 PF18816.1 CCC69808.1 - 5.7e-19 68.2 0.3 4.5e-18 65.3 0.0 2.8 2 0 0 2 2 2 1 Importin repeat HEAT PF02985.22 CCC69808.1 - 1.8e-18 65.0 3.5 0.00089 19.3 0.0 9.4 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 CCC69808.1 - 5.2e-16 58.8 0.1 1.2e-06 28.8 0.0 7.0 4 2 2 6 6 6 4 HEAT repeats RIX1 PF08167.12 CCC69808.1 - 3.5e-09 36.7 1.5 4.1e-05 23.4 0.2 4.6 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis Arm PF00514.23 CCC69808.1 - 1.6e-06 27.9 1.8 1.5 9.0 0.3 5.6 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 CCC69808.1 - 4.4e-06 27.2 0.1 0.14 12.8 0.0 5.6 5 2 2 7 7 7 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 CCC69808.1 - 9.3e-06 25.6 1.5 0.025 14.5 0.2 5.8 6 2 1 7 7 7 1 Domain of unknown function (DUF3385) MMS19_C PF12460.8 CCC69808.1 - 0.0001 21.6 20.0 0.0033 16.6 4.4 5.0 4 2 1 6 6 6 2 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 CCC69808.1 - 0.00023 20.8 0.9 0.15 11.6 0.3 4.4 4 2 1 5 5 5 1 CLASP N terminal DNA_alkylation PF08713.11 CCC69808.1 - 0.0013 18.5 0.0 0.0082 15.9 0.0 2.4 2 0 0 2 2 2 1 DNA alkylation repair enzyme RTP1_C1 PF10363.9 CCC69808.1 - 0.0028 17.8 1.0 8.6 6.6 0.0 4.5 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 CCC69808.1 - 0.0047 16.1 3.7 0.018 14.2 0.1 3.4 4 1 1 5 5 5 1 Interferon-related developmental regulator (IFRD) ParcG PF10274.9 CCC69808.1 - 0.021 15.0 3.6 0.98 9.5 0.0 3.2 3 0 0 3 3 3 0 Parkin co-regulated protein eIF-3c_N PF05470.12 CCC69809.1 - 1.4e-165 552.1 18.8 2.2e-129 432.5 6.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 CCC69809.1 - 2.3e-09 37.7 3.2 4.4e-09 36.8 0.2 3.0 3 0 0 3 3 3 1 PCI domain Ribosomal_L27_C PF18471.1 CCC69809.1 - 0.00071 19.1 1.9 0.00071 19.1 1.9 2.3 3 0 0 3 3 3 1 Ribosomal L27 protein C-terminal domain DUF3069 PF11269.8 CCC69809.1 - 0.017 15.3 1.1 0.6 10.4 0.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) SURF2 PF05477.11 CCC69809.1 - 3.2 7.4 7.5 7.3 6.2 7.5 1.5 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) GrpE PF01025.19 CCC69809.1 - 4.4 6.9 10.6 0.98 9.1 0.3 3.5 3 0 0 3 3 3 0 GrpE Methyltrn_RNA_3 PF02598.17 CCC69810.1 - 7.1e-79 265.3 0.1 8.4e-79 265.0 0.1 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase IPP-2 PF04979.14 CCC69811.1 - 2.1e-22 80.3 14.0 2.1e-22 80.3 14.0 2.0 2 0 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) DUF4513 PF14983.6 CCC69811.1 - 0.075 13.1 0.1 0.21 11.7 0.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4513) Proteasome PF00227.26 CCC69812.1 - 1.3e-44 152.0 0.0 1.6e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCC69812.1 - 7.3e-12 44.7 0.1 1.3e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.16 CCC69812.1 - 0.039 13.9 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK DUF3336 PF11815.8 CCC69813.1 - 1.9e-25 89.2 0.0 3.9e-25 88.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CCC69813.1 - 2.4e-07 31.1 0.0 4.8e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase ELP6 PF09807.9 CCC69814.1 - 0.0011 18.4 0.0 0.0025 17.3 0.0 1.3 1 1 0 1 1 1 1 Elongation complex protein 6 SURF4 PF02077.15 CCC69815.1 - 3.9e-99 331.6 13.9 4.5e-99 331.4 13.9 1.0 1 0 0 1 1 1 1 SURF4 family DUF2207 PF09972.9 CCC69815.1 - 2.4 6.8 11.8 3.2 6.4 0.1 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.16 CCC69816.1 - 8.6e-10 38.1 43.8 1.6e-07 30.6 43.6 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_72 PF03198.14 CCC69817.1 - 1.4e-146 487.8 10.3 1.4e-146 487.8 10.3 1.5 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.13 CCC69817.1 - 2.6e-26 92.1 7.8 7.9e-26 90.6 7.8 1.9 1 0 0 1 1 1 1 X8 domain Apt1 PF10351.9 CCC69817.1 - 2.5 6.9 5.2 3.4 6.4 5.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Glucan_synthase PF02364.15 CCC69818.1 - 0 1344.6 6.8 0 1344.0 6.8 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CCC69818.1 - 1.5e-44 151.5 1.7 6.9e-44 149.3 1.7 2.2 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_17 PF00332.18 CCC69819.1 - 9e-11 41.9 2.4 5.5e-10 39.3 2.4 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Macoilin PF09726.9 CCC69819.1 - 0.22 10.1 3.4 0.26 9.8 3.4 1.1 1 0 0 1 1 1 0 Macoilin family DUF4692 PF15763.5 CCC69819.1 - 0.23 11.9 6.5 0.39 11.2 6.5 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Peptidase_M17_N PF02789.17 CCC69819.1 - 0.38 10.6 4.3 2.1 8.2 0.0 2.9 4 0 0 4 4 4 0 Cytosol aminopeptidase family, N-terminal domain AF-4 PF05110.13 CCC69819.1 - 0.49 8.4 12.5 0.6 8.1 12.5 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PAP1 PF08601.10 CCC69819.1 - 0.78 9.4 13.3 1.2 8.8 13.3 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 Miga PF10265.9 CCC69819.1 - 1 8.3 7.4 1.5 7.7 7.4 1.2 1 0 0 1 1 1 0 Mitoguardin SR-25 PF10500.9 CCC69819.1 - 2.8 7.5 17.2 5.2 6.6 17.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 CCC69819.1 - 3.6 8.3 13.1 8.5 7.1 13.1 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein ATF7IP_BD PF16788.5 CCC69819.1 - 4.4 7.3 8.9 8.9 6.3 8.9 1.5 1 0 0 1 1 1 0 ATF-interacting protein binding domain RAP1 PF07218.11 CCC69819.1 - 5.2 5.2 10.5 7.2 4.8 10.5 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) USP7_C2 PF14533.6 CCC69820.1 - 4e-59 199.8 8.4 1.7e-58 197.7 3.9 2.7 2 0 0 2 2 2 1 Ubiquitin-specific protease C-terminal UCH PF00443.29 CCC69820.1 - 1.8e-46 158.7 2.7 5.1e-46 157.3 2.7 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.8 CCC69820.1 - 2.7e-31 108.7 4.4 5.5e-31 107.7 1.5 2.6 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH_1 PF13423.6 CCC69820.1 - 1.8e-22 80.4 1.1 7.2e-22 78.4 0.1 2.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UN_NPL4 PF11543.8 CCC69820.1 - 0.017 15.6 1.5 8.1 7.0 0.1 3.6 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 RNA12 PF10443.9 CCC69821.1 - 4.1e-171 569.6 2.2 2.6e-170 567.0 0.7 2.1 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.22 CCC69821.1 - 3.3e-07 30.0 0.0 7.4e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.6 CCC69821.1 - 0.0023 18.0 2.8 0.025 14.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATPase_2 PF01637.18 CCC69821.1 - 0.0026 17.7 0.6 0.011 15.6 0.3 2.3 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea DUF3589 PF12141.8 CCC69822.1 - 3.8e-74 250.1 5.2 1.5e-51 175.5 0.1 3.6 2 1 1 3 3 3 2 Beta-mannosyltransferases RST PF12174.8 CCC69822.1 - 0.048 13.6 0.6 0.21 11.5 0.0 2.5 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain CDC45 PF02724.14 CCC69822.1 - 0.082 11.2 9.9 0.16 10.3 9.9 1.4 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 CCC69822.1 - 3.6 7.3 25.2 0.21 11.4 19.6 1.8 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 AAA_23 PF13476.6 CCC69822.1 - 5.8 7.4 23.6 0.58 10.6 12.8 2.5 2 0 0 2 2 2 0 AAA domain Epimerase PF01370.21 CCC69823.1 - 1.7e-16 60.4 0.0 2.4e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCC69823.1 - 1.2e-12 47.5 0.0 1.6e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 CCC69823.1 - 7.1e-08 32.5 0.0 1.9e-07 31.1 0.0 1.8 3 0 0 3 3 3 1 NAD(P)H-binding adh_short PF00106.25 CCC69823.1 - 7.3e-08 32.1 0.2 1.9e-06 27.4 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 CCC69823.1 - 1.8e-07 30.9 0.0 3.6e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 CCC69823.1 - 7.2e-06 25.4 0.0 4.1e-05 22.9 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 CCC69823.1 - 0.00071 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCC69823.1 - 0.0016 17.6 0.1 0.01 15.0 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CCC69823.1 - 0.019 14.5 0.0 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family ABC_membrane PF00664.23 CCC69824.1 - 3e-43 148.5 12.2 3.8e-43 148.1 12.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 CCC69824.1 - 5e-33 114.5 0.0 9.4e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 CCC69824.1 - 2e-07 30.7 0.0 0.00041 19.8 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCC69824.1 - 0.0011 18.7 0.1 0.0027 17.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 CCC69824.1 - 0.0034 17.7 0.0 0.017 15.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCC69824.1 - 0.004 17.6 0.0 0.0088 16.4 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Gtr1_RagA PF04670.12 CCC69824.1 - 0.0054 16.1 0.1 0.012 14.9 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_21 PF13304.6 CCC69824.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 CCC69824.1 - 0.019 14.7 0.0 0.054 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 CCC69824.1 - 0.02 13.7 0.3 0.25 10.1 0.1 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class DUF3987 PF13148.6 CCC69824.1 - 0.023 13.7 0.0 0.049 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA PF00004.29 CCC69824.1 - 0.066 13.6 0.0 0.47 10.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 CCC69824.1 - 0.074 13.5 5.0 0.56 10.7 0.2 3.0 2 1 0 3 3 3 0 AAA domain GATase_6 PF13522.6 CCC69825.1 - 6.8e-12 45.7 0.0 2e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CCC69825.1 - 4.4e-09 36.3 0.0 7.9e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 CCC69825.1 - 6.1e-08 32.3 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 CCC69825.1 - 0.00032 19.7 0.0 0.00052 19.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II F-box PF00646.33 CCC69826.1 - 0.1 12.5 0.0 0.26 11.2 0.0 1.7 1 0 0 1 1 1 0 F-box domain XLF PF09302.11 CCC69827.1 - 3e-19 69.9 2.0 7.5e-19 68.6 2.0 1.6 1 0 0 1 1 1 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component ORF6N PF10543.9 CCC69827.1 - 0.0085 16.3 0.6 0.059 13.6 0.3 2.2 2 0 0 2 2 2 1 ORF6N domain Peroxidase_ext PF11895.8 CCC69827.1 - 0.13 12.2 0.1 0.29 11.1 0.1 1.5 1 0 0 1 1 1 0 Fungal peroxidase extension region Ribosomal_S28e PF01200.18 CCC69828.1 - 2.6e-32 110.6 2.5 2.8e-32 110.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e S_layer_C PF05124.12 CCC69828.1 - 0.16 11.9 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region Red1 PF07964.11 CCC69829.1 - 1.4e-82 278.2 69.0 2e-80 271.1 55.3 3.6 3 1 0 3 3 3 2 Rec10 / Red1 DUF2280 PF10045.9 CCC69829.1 - 0.029 14.7 0.5 0.58 10.4 0.1 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2280) Myb_DNA-bind_6 PF13921.6 CCC69829.1 - 0.034 14.4 1.9 3.3 8.0 0.1 3.3 2 1 0 2 2 2 0 Myb-like DNA-binding domain TMA7 PF09072.10 CCC69830.1 - 3.6e-23 82.2 19.3 3.9e-23 82.0 19.3 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Ras PF00071.22 CCC69831.1 - 1e-56 191.0 0.5 1.2e-56 190.8 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC69831.1 - 1.1e-37 129.0 0.2 1.9e-37 128.1 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC69831.1 - 2.2e-15 56.6 0.5 2.4e-15 56.4 0.5 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCC69831.1 - 9.3e-06 25.7 0.0 2.5e-05 24.3 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCC69831.1 - 1.2e-05 25.3 0.1 0.08 12.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 CCC69831.1 - 1.9e-05 24.2 0.0 3.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 CCC69831.1 - 6.4e-05 22.4 0.2 8.4e-05 22.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCC69831.1 - 0.0012 18.4 0.1 0.012 15.2 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATPase_2 PF01637.18 CCC69831.1 - 0.0016 18.4 0.5 0.0042 17.0 0.1 1.7 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea PduV-EutP PF10662.9 CCC69831.1 - 0.0039 16.9 1.0 0.034 13.9 1.0 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 CCC69831.1 - 0.0055 16.2 0.0 0.0088 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 CCC69831.1 - 0.015 15.0 0.2 0.023 14.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CCC69831.1 - 0.028 14.7 0.0 0.063 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CCC69831.1 - 0.044 14.2 0.0 0.067 13.6 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 CCC69831.1 - 0.078 13.0 0.2 0.12 12.4 0.2 1.5 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.12 CCC69831.1 - 0.082 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DAGK_cat PF00781.24 CCC69832.1 - 3.3e-26 91.4 0.0 5.5e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Rib_recp_KP_reg PF05104.12 CCC69832.1 - 0.00031 21.8 1.6 0.00056 21.0 1.6 1.4 1 0 0 1 1 1 1 Ribosome receptor lysine/proline rich region SOBP PF15279.6 CCC69832.1 - 5.4 7.5 14.0 8.9 6.8 14.0 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein zf-C2H2 PF00096.26 CCC69833.1 - 1.9e-09 37.5 13.5 9.7e-05 22.6 3.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC69833.1 - 5.2e-09 36.1 4.5 5.2e-09 36.1 4.5 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC69833.1 - 0.00021 21.9 12.5 0.012 16.4 3.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCC69833.1 - 0.00048 20.1 1.2 0.00048 20.1 1.2 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_8 PF15909.5 CCC69833.1 - 0.027 14.8 2.9 0.056 13.7 2.9 1.5 1 0 0 1 1 1 0 C2H2-type zinc ribbon SOG2 PF10428.9 CCC69833.1 - 0.047 12.9 2.6 0.049 12.8 2.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein BolA PF01722.18 CCC69833.1 - 0.11 12.8 0.2 0.24 11.7 0.2 1.6 1 0 0 1 1 1 0 BolA-like protein gag_pre-integrs PF13976.6 CCC69833.1 - 0.52 10.2 7.6 0.1 12.5 2.9 2.3 2 0 0 2 2 2 0 GAG-pre-integrase domain zf-met PF12874.7 CCC69833.1 - 4.7 7.7 6.6 0.73 10.3 0.8 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CAP_N PF01213.19 CCC69833.1 - 8.3 5.8 7.7 13 5.1 7.7 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CBM_21 PF03370.13 CCC69834.1 - 4.7e-24 84.7 5.8 4.7e-24 84.7 5.8 2.1 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CCC69834.1 - 0.00061 20.3 6.9 0.00061 20.3 6.9 2.8 2 1 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) DUF4957 PF16318.5 CCC69834.1 - 0.008 16.1 2.6 0.008 16.1 2.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4957) Fungal_trans PF04082.18 CCC69835.1 - 4.1e-41 140.8 0.2 6.2e-41 140.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC69835.1 - 8.8e-09 35.4 10.6 1.6e-08 34.5 10.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.10 CCC69835.1 - 0.83 10.0 5.5 2.4 8.5 5.5 1.8 1 0 0 1 1 1 0 Opy2 protein zf-RRN7 PF11781.8 CCC69837.1 - 3.3e-09 36.3 1.0 5.6e-09 35.5 1.0 1.4 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Clat_adaptor_s PF01217.20 CCC69838.1 - 6.6e-57 191.4 2.2 7.9e-57 191.2 2.2 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-UBR PF02207.20 CCC69839.1 - 1.1e-10 41.6 11.0 3.2e-10 40.0 11.0 1.9 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) tRNA-synt_1b PF00579.25 CCC69840.1 - 4.2e-76 256.1 0.0 5.5e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HlyIII PF03006.20 CCC69841.1 - 1.5e-70 237.4 17.1 1.9e-70 237.1 17.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related Cytochrom_C552 PF02335.15 CCC69841.1 - 0.072 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Cytochrome c552 CBM_21 PF03370.13 CCC69842.1 - 3.3e-24 85.2 6.1 9.3e-24 83.8 6.1 1.8 1 0 0 1 1 1 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CCC69842.1 - 0.00088 19.8 6.8 0.00088 19.8 6.8 2.8 2 1 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) DUF4957 PF16318.5 CCC69842.1 - 0.0095 15.9 2.6 0.0095 15.9 2.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4957) Lyase_1 PF00206.20 CCC69843.1 - 1.9e-116 388.9 0.0 2.7e-116 388.3 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 CCC69843.1 - 2.9e-25 88.4 0.2 4.1e-24 84.7 0.1 2.4 2 0 0 2 2 2 1 Fumarase C C-terminus BRCA2 PF00634.18 CCC69843.1 - 0.15 11.8 0.1 7.2 6.4 0.0 3.0 3 0 0 3 3 3 0 BRCA2 repeat Peptidase_S8 PF00082.22 CCC69844.1 - 7.8e-34 117.3 0.2 1.5e-33 116.4 0.2 1.4 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CCC69844.1 - 1.6e-06 28.7 0.0 3.1e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 SQHop_cyclase_C PF13243.6 CCC69844.1 - 0.054 12.6 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Squalene-hopene cyclase C-terminal domain Acetyltransf_1 PF00583.25 CCC69845.1 - 0.00013 22.2 0.1 0.00051 20.3 0.1 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 CCC69845.1 - 0.00018 21.8 0.0 0.00033 21.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCC69845.1 - 0.00093 19.1 0.1 0.21 11.5 0.0 3.1 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.7 CCC69845.1 - 0.0034 17.3 0.0 0.033 14.1 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain LINES_N PF14694.6 CCC69845.1 - 0.022 14.3 0.2 0.03 13.8 0.2 1.1 1 0 0 1 1 1 0 Lines N-terminus PrlF_antitoxin PF15937.5 CCC69845.1 - 0.1 13.0 0.1 0.95 9.9 0.0 2.1 1 1 1 2 2 2 0 prlF antitoxin for toxin YhaV_toxin DNA_ligase_A_M PF01068.21 CCC69846.1 - 2.2e-51 174.4 0.1 4.3e-51 173.5 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 CCC69846.1 - 1.9e-24 87.0 0.1 3.1e-24 86.2 0.1 1.4 1 0 0 1 1 1 1 DNA ligase N terminus BRCT_2 PF16589.5 CCC69846.1 - 8.8e-21 74.1 0.2 1e-10 41.9 0.1 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RNA_ligase PF09414.10 CCC69846.1 - 5e-11 43.2 0.0 1.1e-10 42.1 0.0 1.6 1 0 0 1 1 1 1 RNA ligase BRCT PF00533.26 CCC69846.1 - 1e-09 38.6 0.3 0.00012 22.3 0.1 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.15 CCC69846.1 - 0.00049 20.7 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.19 CCC69846.1 - 0.002 18.0 0.8 0.76 9.6 0.7 2.7 1 1 1 2 2 2 1 mRNA capping enzyme, catalytic domain RTT107_BRCT_5 PF16770.5 CCC69846.1 - 0.0049 16.7 0.1 3.1 7.7 0.0 3.2 2 1 0 2 2 2 1 Regulator of Ty1 transposition protein 107 BRCT domain LIP1 PF15904.5 CCC69846.1 - 0.13 12.6 0.0 0.45 10.9 0.0 1.9 1 0 0 1 1 1 0 LKB1 serine/threonine kinase interacting protein 1 Fcf1 PF04900.12 CCC69847.1 - 1e-33 115.6 1.2 2.3e-33 114.5 1.2 1.6 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.14 CCC69847.1 - 0.43 8.8 5.0 0.53 8.5 5.0 1.2 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 CCC69847.1 - 2.5 7.7 7.5 39 3.9 5.3 2.3 2 0 0 2 2 2 0 FAM176 family Presenilin PF01080.17 CCC69847.1 - 6.2 5.5 5.4 9 4.9 5.4 1.2 1 0 0 1 1 1 0 Presenilin SGTA_dimer PF16546.5 CCC69848.1 - 6.4e-15 54.7 0.6 1.6e-14 53.4 0.6 1.7 1 0 0 1 1 1 1 Homodimerisation domain of SGTA TPR_2 PF07719.17 CCC69848.1 - 6.9e-14 50.8 5.4 0.0035 17.3 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCC69848.1 - 2.2e-09 36.7 7.1 0.0024 17.6 0.6 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCC69848.1 - 4.9e-08 32.5 4.5 0.038 13.7 0.2 3.7 2 1 1 3 3 3 3 TPR repeat TPR_8 PF13181.6 CCC69848.1 - 5.3e-07 29.4 6.5 0.014 15.6 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCC69848.1 - 1.7e-05 25.3 3.9 0.24 12.1 0.1 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCC69848.1 - 5.3e-05 23.0 1.0 0.62 10.2 0.1 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCC69848.1 - 0.00011 22.5 4.1 0.45 10.8 0.4 4.6 4 1 0 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CCC69848.1 - 0.00022 20.6 0.1 0.085 12.3 0.0 3.9 4 0 0 4 4 4 1 SHNi-TPR TPR_14 PF13428.6 CCC69848.1 - 0.00027 21.5 0.3 12 7.0 0.0 4.8 4 1 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 CCC69848.1 - 0.00032 20.7 3.7 0.015 15.3 0.2 3.6 5 0 0 5 5 5 1 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 CCC69848.1 - 0.00079 19.9 2.5 0.072 13.6 0.1 3.6 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 CCC69848.1 - 0.0009 19.0 4.4 1.9 8.5 0.0 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCC69848.1 - 0.0032 18.0 4.6 2.4 9.0 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 CCC69848.1 - 0.013 15.8 1.0 3.1 8.2 0.0 3.2 2 2 1 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 CCC69848.1 - 0.014 15.9 0.8 0.3 11.5 0.0 2.9 2 1 1 3 3 3 0 Bacterial transcriptional activator domain Fis1_TPR_C PF14853.6 CCC69848.1 - 0.018 15.1 2.5 2.1 8.5 0.0 3.3 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 CCC69848.1 - 0.053 13.7 0.6 1.7 9.0 0.7 3.0 2 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 CCC69848.1 - 0.065 13.6 0.2 0.7 10.4 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat Cnd1 PF12717.7 CCC69849.1 - 1.7e-49 168.0 14.1 1.7e-44 151.7 0.5 3.9 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 CCC69849.1 - 3.5e-46 157.1 3.0 8.4e-46 155.8 3.0 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 CCC69849.1 - 7.7e-11 41.3 1.7 0.36 11.2 0.0 5.9 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 CCC69849.1 - 9.9e-10 38.7 0.0 0.0046 17.3 0.0 3.4 2 1 0 2 2 2 2 HEAT repeats Cnd3 PF12719.7 CCC69849.1 - 0.0005 19.3 0.7 0.0005 19.3 0.7 4.2 4 1 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 CCC69849.1 - 0.0036 17.4 1.1 1.6 8.9 0.0 3.6 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 CCC69849.1 - 0.026 15.0 0.3 62 4.3 0.0 4.1 4 0 0 4 4 4 0 HEAT-like repeat Med29 PF11568.8 CCC69849.1 - 0.12 12.6 1.9 0.55 10.5 1.9 2.2 1 1 0 1 1 1 0 Mediator complex subunit 29 TAN PF11640.8 CCC69849.1 - 4.8 7.3 8.4 1.5 8.9 0.4 3.4 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair DUF4187 PF13821.6 CCC69850.1 - 3.2e-19 68.5 1.0 5.5e-19 67.7 1.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_jaz PF12171.8 CCC69850.1 - 0.017 15.4 0.7 0.03 14.6 0.7 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding DcpS PF05652.12 CCC69851.1 - 3.1e-36 124.3 0.0 4.9e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 CCC69851.1 - 2.1e-34 118.4 0.3 5.5e-34 117.1 0.1 1.9 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding Longin PF13774.6 CCC69852.1 - 4.5e-22 77.9 0.3 7.3e-22 77.2 0.3 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 CCC69852.1 - 2.1e-16 59.5 0.2 5.2e-16 58.2 0.2 1.6 1 0 0 1 1 1 1 Synaptobrevin E1-E2_ATPase PF00122.20 CCC69852.1 - 0.15 11.6 0.2 0.26 10.8 0.2 1.4 1 1 0 1 1 1 0 E1-E2 ATPase DUF1664 PF07889.12 CCC69852.1 - 0.29 11.2 2.6 0.3 11.1 1.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Zn_clus PF00172.18 CCC69853.1 - 1.7e-05 24.8 9.6 3.5e-05 23.8 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.18 CCC69853.1 - 4.5e-05 22.6 5.0 0.00048 19.2 5.0 2.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Syntaxin_2 PF14523.6 CCC69853.1 - 1.1 9.7 5.0 0.26 11.7 0.3 2.4 3 0 0 3 3 3 0 Syntaxin-like protein Sof1 PF04158.14 CCC69854.1 - 1.8e-27 95.5 14.7 4.2e-27 94.2 14.7 1.7 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 CCC69854.1 - 8e-27 93.0 3.9 3.7e-06 27.6 0.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC69854.1 - 4.2e-07 30.2 0.8 0.19 12.0 0.0 5.3 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCC69854.1 - 2.3e-05 23.5 1.4 0.11 11.5 0.1 3.3 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 CCC69854.1 - 0.00099 19.1 0.6 0.47 10.5 0.0 3.7 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Utp8 PF10395.9 CCC69854.1 - 0.0039 15.8 3.0 0.01 14.4 0.7 2.1 2 0 0 2 2 2 1 Utp8 family WD40_like PF17005.5 CCC69854.1 - 0.028 13.8 1.9 0.069 12.5 0.0 2.4 3 0 0 3 3 3 0 WD40-like domain Phage_spike_2 PF18781.1 CCC69854.1 - 0.096 12.7 0.1 0.59 10.2 0.1 2.3 2 0 0 2 2 2 0 Phage spike trimer HARP PF07443.13 CCC69854.1 - 0.25 11.0 1.6 1.6 8.4 0.1 3.0 3 0 0 3 3 3 0 HepA-related protein (HARP) NIF PF03031.18 CCC69855.1 - 1e-51 174.8 0.2 2.1e-51 173.8 0.2 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase UPF0524 PF15823.5 CCC69855.1 - 0.13 11.6 3.0 0.14 11.5 1.8 1.6 2 0 0 2 2 2 0 UPF0524 of C3orf70 NPCC PF08058.11 CCC69856.1 - 2e-36 124.9 1.9 3.1e-36 124.3 1.9 1.3 1 0 0 1 1 1 1 Nuclear pore complex component PNP_UDP_1 PF01048.20 CCC69857.1 - 1.4e-34 119.4 0.0 1.8e-34 119.1 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily SYS1 PF09801.9 CCC69858.1 - 1.7e-49 167.7 11.8 2e-49 167.4 11.8 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DLIC PF05783.11 CCC69859.1 - 1.7e-08 33.8 0.1 2.5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) DUF1967 PF09269.11 CCC69859.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) COX16 PF14138.6 CCC69860.1 - 5.2e-30 103.8 1.0 2.2e-29 101.7 0.1 1.9 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 SBDS PF01172.18 CCC69861.1 - 2.4e-33 114.1 2.6 3.7e-33 113.4 2.6 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 CCC69861.1 - 3.4e-30 104.5 1.1 3.4e-30 104.5 1.1 2.1 2 0 0 2 2 2 1 SBDS protein C-terminal domain CAMSAP_CKK PF08683.11 CCC69861.1 - 0.045 13.9 0.2 0.12 12.6 0.0 1.7 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated POC3_POC4 PF10448.9 CCC69862.1 - 9.8e-30 103.5 0.3 1.1e-29 103.3 0.3 1.0 1 0 0 1 1 1 1 20S proteasome chaperone assembly proteins 3 and 4 Abhydro_lipase PF04083.16 CCC69863.1 - 5.4e-17 61.1 0.0 1.1e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 CCC69863.1 - 3.8e-06 26.7 0.0 9.6e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCC69863.1 - 0.039 13.2 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Adaptin_N PF01602.20 CCC69864.1 - 1.8e-93 313.9 19.8 2.4e-93 313.5 19.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCC69864.1 - 2.4e-13 50.4 9.0 1.2e-12 48.1 1.9 2.7 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCC69864.1 - 4.1e-06 27.1 0.1 2.2 8.7 0.0 4.1 3 1 1 4 4 4 3 HEAT repeats T_hemolysin PF12261.8 CCC69864.1 - 0.082 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Thermostable hemolysin RTP1_C1 PF10363.9 CCC69864.1 - 0.14 12.4 7.0 0.44 10.7 1.1 3.7 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 LAGLIDADG_WhiA PF14527.6 CCC69866.1 - 0.038 14.1 0.2 0.092 12.8 0.2 1.6 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Mpp10 PF04006.12 CCC69867.1 - 1e-144 483.4 68.6 1.3e-144 483.0 68.6 1.0 1 0 0 1 1 1 1 Mpp10 protein Aa_trans PF01490.18 CCC69868.1 - 2e-81 273.8 29.0 2.4e-81 273.5 29.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.16 CCC69869.1 - 1.7e-36 125.9 21.3 5.3e-36 124.3 22.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.9 CCC69869.1 - 0.11 12.7 0.1 1.7 8.9 0.1 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CRPA PF05745.11 CCC69869.1 - 0.13 12.3 3.9 3.9 7.5 0.1 2.8 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Ssl1 PF04056.14 CCC69870.1 - 9.5e-90 299.6 0.1 1.3e-89 299.1 0.1 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 CCC69870.1 - 2e-25 88.8 10.6 2e-25 88.8 10.6 2.6 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 CCC69870.1 - 8.2e-14 52.2 0.0 1.8e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.21 CCC69870.1 - 0.0079 16.4 5.9 0.0079 16.4 5.9 2.8 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain Tfb4 PF03850.14 CCC69870.1 - 5.1 6.5 9.0 9 5.7 9.0 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 CDC45 PF02724.14 CCC69870.1 - 6.5 4.9 7.4 8.6 4.5 7.4 1.1 1 0 0 1 1 1 0 CDC45-like protein zf-HIT PF04438.16 CCC69870.1 - 6.6 6.7 22.0 1.8 8.5 6.8 3.2 3 0 0 3 3 3 0 HIT zinc finger Response_reg PF00072.24 CCC69871.1 - 3.5e-20 72.2 0.1 4e-18 65.6 0.1 2.5 1 1 0 1 1 1 1 Response regulator receiver domain Pam16 PF03656.13 CCC69872.1 - 1.9e-06 27.9 0.1 2.2e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 CCC69872.1 - 0.00092 19.3 0.4 0.0017 18.5 0.4 1.5 1 0 0 1 1 1 1 DnaJ domain BAAT_C PF08840.11 CCC69872.1 - 0.022 14.7 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal MCM PF00493.23 CCC69873.1 - 1.7e-104 347.9 0.0 3.5e-104 346.8 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCC69873.1 - 2e-36 124.6 0.1 3.9e-36 123.7 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCC69873.1 - 7.2e-27 93.6 3.0 1.8e-26 92.3 3.0 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCC69873.1 - 4e-16 59.5 0.2 1e-15 58.2 0.2 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 CCC69873.1 - 3e-06 27.3 0.0 1.1e-05 25.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCC69873.1 - 3.3e-06 26.6 0.0 0.00057 19.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CCC69873.1 - 0.00033 20.5 0.1 0.0019 18.0 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCC69873.1 - 0.012 15.3 0.0 0.97 9.1 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF1822 PF08852.11 CCC69873.1 - 0.065 12.3 3.8 0.6 9.1 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1822) AAA PF00004.29 CCC69873.1 - 0.093 13.2 0.0 1 9.8 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) LSM PF01423.22 CCC69874.1 - 4.7e-18 64.6 0.6 6.3e-18 64.2 0.6 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CCC69874.1 - 0.084 12.5 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Hfq protein DEAD PF00270.29 CCC69875.1 - 4.6e-40 137.2 1.7 8e-40 136.5 1.7 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC69875.1 - 4.5e-31 107.5 1.3 1.7e-30 105.6 0.1 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC69875.1 - 1.4e-06 28.4 1.4 3.4e-06 27.2 0.1 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DnaI_N PF07319.11 CCC69875.1 - 0.056 14.1 4.9 4.7 8.0 0.3 3.4 2 2 0 2 2 2 0 Primosomal protein DnaI N-terminus CPSF73-100_C PF11718.8 CCC69876.1 - 4e-58 196.5 3.3 6e-58 196.0 3.3 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 CCC69876.1 - 3.3e-30 104.6 0.0 7.1e-30 103.5 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.27 CCC69876.1 - 1.2e-24 87.4 0.7 1.8e-24 86.8 0.7 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CCC69876.1 - 3.9e-21 75.4 0.1 9.4e-21 74.1 0.1 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 CCC69876.1 - 9.6e-18 63.9 0.0 1.9e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 CCC69876.1 - 8.6e-08 31.9 0.2 1.5e-06 27.8 0.1 2.8 3 1 0 3 3 3 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CCC69876.1 - 5.6e-06 26.3 0.2 3.5e-05 23.8 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 CCC69876.1 - 0.016 14.5 0.0 0.054 12.7 0.0 1.8 2 0 0 2 2 2 0 Putative beta-lactamase-like family Fungal_trans PF04082.18 CCC69877.1 - 1.4e-17 63.7 6.8 4.1e-17 62.1 6.8 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC69877.1 - 3.1e-06 27.2 10.2 7.7e-06 25.9 10.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cas9_a PF18470.1 CCC69877.1 - 2.3 7.7 5.8 0.82 9.2 0.7 2.5 3 0 0 3 3 3 0 Cas9 alpha-helical lobe domain RF-1 PF00472.20 CCC69878.1 - 2.9e-17 62.6 11.8 1.5e-16 60.4 11.8 1.9 1 1 0 1 1 1 1 RF-1 domain FAM176 PF14851.6 CCC69878.1 - 1.7 8.3 6.8 2.6 7.7 6.8 1.2 1 0 0 1 1 1 0 FAM176 family DUF1640 PF07798.11 CCC69879.1 - 4.6e-17 62.6 5.6 4.6e-17 62.6 5.6 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1640) Tweety PF04906.13 CCC69879.1 - 0.074 11.7 2.4 0.22 10.1 2.4 1.7 1 1 0 1 1 1 0 Tweety DsrC PF04358.13 CCC69879.1 - 0.095 13.2 1.7 0.13 12.8 0.1 1.9 2 0 0 2 2 2 0 DsrC like protein ECH_1 PF00378.20 CCC69880.1 - 1.1e-16 60.9 0.1 2e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CCC69880.1 - 1.3e-08 34.7 0.0 2.8e-08 33.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Methyltransf_16 PF10294.9 CCC69881.1 - 1.7e-14 54.0 0.0 2.2e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 CCC69881.1 - 0.00012 22.0 0.0 0.00016 21.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC69881.1 - 0.1 13.4 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_18 PF00704.28 CCC69882.1 - 3.7e-26 92.6 1.2 6.5e-26 91.8 1.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.13 CCC69882.1 - 3.8e-06 26.8 3.0 3.8e-06 26.8 3.0 4.1 4 0 0 4 4 4 1 Carbohydrate binding domain (family 19) Di19_C PF14571.6 CCC69882.1 - 0.21 12.2 0.2 0.21 12.2 0.2 2.9 2 1 2 4 4 4 0 Stress-induced protein Di19, C-terminal DUF1765 PF08578.10 CCC69882.1 - 0.65 10.5 3.2 3.6 8.1 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1765) GCIP PF13324.6 CCC69883.1 - 1.4e-40 139.6 5.5 1.9e-40 139.1 5.5 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Baculo_PEP_C PF04513.12 CCC69883.1 - 0.078 13.0 8.4 1.6 8.8 2.9 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4972 PF16342.5 CCC69883.1 - 0.1 12.3 2.7 0.2 11.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4972) Ribosomal_S30 PF04758.14 CCC69884.1 - 1.3e-29 102.1 6.4 1.5e-29 102.0 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Hus1 PF04005.12 CCC69885.1 - 1.3e-21 77.0 1.2 4.7e-17 62.0 0.1 2.3 2 0 0 2 2 2 2 Hus1-like protein GTP_EFTU PF00009.27 CCC69886.1 - 7.8e-46 156.1 0.1 1.5e-45 155.2 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 CCC69886.1 - 2.4e-42 143.4 6.7 5.6e-42 142.3 6.7 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 CCC69886.1 - 1.2e-15 57.3 0.0 6.5e-15 54.9 0.0 2.3 2 1 0 2 2 2 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 CCC69886.1 - 8.8e-06 25.8 1.1 1.6e-05 24.9 0.1 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 CCC69886.1 - 1.4e-05 25.3 0.9 3.5e-05 24.1 0.9 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Ras PF00071.22 CCC69886.1 - 0.00058 19.5 0.1 0.0017 18.0 0.1 1.8 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CCC69886.1 - 0.0017 17.9 0.1 0.0077 15.7 0.1 2.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit RF3_C PF16658.5 CCC69886.1 - 0.011 15.6 0.1 0.035 13.9 0.0 1.9 2 0 0 2 2 2 0 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 CCC69886.1 - 0.028 14.5 0.0 0.08 13.1 0.0 1.8 1 0 0 1 1 1 0 Elongation Factor G, domain II Roc PF08477.13 CCC69886.1 - 0.045 14.0 0.2 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 CCC69886.1 - 0.073 13.1 0.1 0.29 11.2 0.1 2.0 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain NAT PF04768.13 CCC69886.1 - 0.1 12.3 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase FeoB_N PF02421.18 CCC69886.1 - 0.21 11.1 2.6 0.37 10.3 0.4 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B Epimerase PF01370.21 CCC69887.1 - 1.5e-05 24.6 0.0 2.8e-05 23.7 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 CCC69887.1 - 0.0026 17.7 0.0 0.22 11.4 0.0 2.9 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CCC69887.1 - 0.011 14.8 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.12 CCC69887.1 - 0.017 14.3 0.1 0.059 12.5 0.1 2.1 1 1 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.19 CCC69887.1 - 0.11 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 CCC69887.1 - 0.12 11.8 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase TPR_1 PF00515.28 CCC69888.1 - 4.8e-05 23.0 0.7 0.18 11.7 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCC69888.1 - 0.00072 19.5 0.9 0.64 10.3 0.1 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF1542 PF07564.11 CCC69888.1 - 0.0078 16.3 1.4 0.014 15.5 0.6 1.8 1 1 0 1 1 1 1 Domain of Unknown Function (DUF1542) LOH1CR12 PF10158.9 CCC69888.1 - 0.027 14.5 0.1 0.051 13.6 0.1 1.4 1 0 0 1 1 1 0 Tumour suppressor protein Baculo_11_kDa PF06143.11 CCC69889.1 - 0.057 13.0 1.5 0.097 12.3 1.5 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Ninjurin PF04923.12 CCC69889.1 - 0.065 13.2 1.2 0.097 12.6 1.2 1.3 1 1 0 1 1 1 0 Ninjurin Sigma_reg_N PF13800.6 CCC69889.1 - 0.15 12.4 1.1 0.29 11.4 1.1 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal ATP-synt_8 PF00895.20 CCC69889.1 - 7.6 7.1 6.3 5.1 7.6 3.2 2.3 2 1 0 2 2 2 0 ATP synthase protein 8 zf-U1 PF06220.12 CCC69890.1 - 2.6e-18 65.5 5.2 7.1e-18 64.1 5.2 1.8 1 0 0 1 1 1 1 U1 zinc finger G_glu_transpept PF01019.21 CCC69891.1 - 8.2e-139 463.7 0.0 9.8e-139 463.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cellulase PF00150.18 CCC69892.1 - 2.7e-14 53.3 0.3 6.8e-14 51.9 0.3 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HRI1 PF16815.5 CCC69893.1 - 5.6e-45 153.8 0.0 6.2e-45 153.7 0.0 1.0 1 0 0 1 1 1 1 Protein HRI1 Cornichon PF03311.14 CCC69894.1 - 4.3e-46 156.2 7.7 5e-46 156.0 7.7 1.0 1 0 0 1 1 1 1 Cornichon protein MTHFR PF02219.17 CCC69895.1 - 3e-122 407.4 0.0 4e-122 407.0 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Aldo_ket_red PF00248.21 CCC69896.1 - 4.7e-55 186.9 0.0 5.4e-55 186.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.12 CCC69896.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.5 2 0 0 2 2 2 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Scs3p PF10261.9 CCC69897.1 - 1.8e-73 247.1 8.2 2.2e-73 246.8 8.2 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Med31 PF05669.12 CCC69898.1 - 9.5e-26 89.6 1.0 1.2e-25 89.3 1.0 1.1 1 0 0 1 1 1 1 SOH1 Dam PF05869.11 CCC69898.1 - 0.14 11.7 0.1 0.17 11.5 0.1 1.1 1 0 0 1 1 1 0 DNA N-6-adenine-methyltransferase (Dam) CPSase_L_D2 PF02786.17 CCC69899.1 - 1.7e-84 282.6 0.1 3.3e-84 281.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CCC69899.1 - 3.7e-68 229.2 0.0 6.8e-68 228.3 0.0 1.5 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CCC69899.1 - 1.1e-38 132.2 0.0 2.4e-38 131.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CCC69899.1 - 2.8e-31 107.8 0.0 3.4e-30 104.3 0.0 2.4 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CCC69899.1 - 2.9e-27 95.9 0.1 7.7e-27 94.5 0.1 1.7 2 0 0 2 2 2 1 HMGL-like Biotin_lipoyl PF00364.22 CCC69899.1 - 6.7e-18 64.3 3.1 6.7e-18 64.3 3.1 2.2 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CCC69899.1 - 3.3e-07 30.0 0.0 7.4e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CCC69899.1 - 3.6e-07 29.9 0.0 7.9e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CCC69899.1 - 2.3e-06 27.3 1.1 0.0059 16.4 0.3 2.9 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CCC69899.1 - 2.9e-06 27.4 0.0 2.3e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain HlyD_D23 PF16576.5 CCC69899.1 - 0.00076 18.8 0.2 0.03 13.5 0.1 2.7 1 1 1 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 CCC69899.1 - 0.0012 18.5 0.0 0.0027 17.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 CCC69899.1 - 0.0019 18.9 0.9 1.3 9.7 0.1 3.7 3 0 0 3 3 3 1 HlyD family secretion protein ATPgrasp_ST PF14397.6 CCC69899.1 - 0.0023 17.2 0.0 0.0055 16.0 0.0 1.6 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 CCC69899.1 - 0.11 12.4 0.8 0.33 10.8 0.8 1.8 1 0 0 1 1 1 0 Glycine cleavage H-protein ATPgrasp_Ter PF15632.6 CCC69899.1 - 0.17 11.7 0.3 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon RnfC_N PF13375.6 CCC69899.1 - 0.59 10.1 3.4 3.4 7.7 1.3 2.8 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain DASH_Duo1 PF08651.10 CCC69900.1 - 1.4e-24 85.7 1.0 1.4e-24 85.7 1.0 2.3 2 1 1 3 3 3 1 DASH complex subunit Duo1 Lzipper-MIP1 PF14389.6 CCC69900.1 - 0.038 14.3 4.6 0.15 12.4 2.0 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 NuDC PF16273.5 CCC69900.1 - 0.13 12.8 4.4 0.25 11.9 4.4 1.4 1 0 0 1 1 1 0 Nuclear distribution C domain CortBP2 PF09727.9 CCC69900.1 - 0.81 9.6 9.3 0.66 9.9 4.2 2.1 2 0 0 2 2 2 0 Cortactin-binding protein-2 Uds1 PF15456.6 CCC69900.1 - 1.5 9.0 9.3 4.6 7.4 6.1 2.5 2 1 0 2 2 2 0 Up-regulated During Septation Kinetochor_Ybp2 PF08568.10 CCC69901.1 - 4e-143 478.2 24.6 4.4e-143 478.1 24.6 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin BCDHK_Adom3 PF10436.9 CCC69902.1 - 7.3e-30 103.9 0.9 1.4e-29 103.1 0.9 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 CCC69902.1 - 0.0027 18.2 0.0 0.18 12.3 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UQ_con PF00179.26 CCC69903.1 - 1.1e-50 170.9 0.1 1.3e-50 170.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCC69903.1 - 0.0086 15.8 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 CCC69903.1 - 0.039 14.3 0.1 0.085 13.1 0.1 1.7 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 CCC69903.1 - 0.064 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 UEV domain Leuk-A4-hydro_C PF09127.11 CCC69903.1 - 0.08 13.0 0.1 1.1 9.4 0.1 2.0 1 1 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal NOA36 PF06524.12 CCC69903.1 - 5.2 6.3 10.0 6.2 6.0 10.0 1.1 1 0 0 1 1 1 0 NOA36 protein CBS PF00571.28 CCC69905.1 - 2.2e-22 79.3 2.6 1.3e-06 28.7 0.0 5.3 5 0 0 5 5 5 5 CBS domain ASCH PF04266.14 CCC69905.1 - 0.034 14.7 0.0 2.1 9.0 0.0 2.9 3 0 0 3 3 3 0 ASCH domain DUF4393 PF14337.6 CCC69905.1 - 0.035 13.9 0.3 0.093 12.5 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4393) FA_desaturase PF00487.24 CCC69906.1 - 9e-19 68.3 17.6 9e-19 68.3 17.6 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 CCC69906.1 - 9.6e-14 51.3 0.0 1.8e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mon1 PF03164.14 CCC69907.1 - 6.4e-142 473.4 1.9 7.9e-142 473.1 1.9 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Ribosomal_S5 PF00333.20 CCC69908.1 - 8.4e-27 93.0 3.1 4e-26 90.8 1.6 2.4 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CCC69908.1 - 2.3e-23 81.4 0.0 3.8e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Nab2 PF11517.8 CCC69909.1 - 7.6e-48 161.0 1.3 1.2e-47 160.4 1.3 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.6 CCC69909.1 - 9.8e-23 79.8 73.6 5.8e-06 26.6 5.7 7.3 7 0 0 7 7 7 6 RNA-binding, Nab2-type zinc finger Nab2p_Zf1 PF18260.1 CCC69909.1 - 8.6e-16 57.5 10.6 8.6e-16 57.5 10.6 3.5 3 0 0 3 3 3 1 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 DUF2508 PF10704.9 CCC69909.1 - 0.016 15.3 0.1 0.031 14.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2508) Imm19 PF15563.6 CCC69909.1 - 0.21 11.1 0.0 0.3 10.5 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 19 DNA_pol_B PF00136.21 CCC69910.1 - 0.035 12.8 0.1 0.042 12.6 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase family B OB_NTP_bind PF07717.16 CCC69911.1 - 7.1e-23 80.8 0.0 3.1e-22 78.7 0.0 2.2 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 CCC69911.1 - 5.9e-22 78.0 0.0 1.5e-21 76.7 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 CCC69911.1 - 1.7e-11 44.4 0.0 4.7e-11 43.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCC69911.1 - 1.4e-09 38.0 0.2 2.4e-09 37.2 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCC69911.1 - 1.8e-06 28.2 0.1 5.4e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CCC69911.1 - 0.00012 21.8 0.1 0.0003 20.5 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_19 PF13245.6 CCC69911.1 - 0.00026 21.4 0.2 0.00046 20.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 CCC69911.1 - 0.00045 20.2 0.1 0.00095 19.2 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 CCC69911.1 - 0.00069 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 CCC69911.1 - 0.0022 18.6 0.0 0.039 14.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain ResIII PF04851.15 CCC69911.1 - 0.0022 18.0 0.1 0.25 11.3 0.1 2.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SSE PF00437.20 CCC69911.1 - 0.02 13.9 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 CCC69911.1 - 0.035 13.6 0.1 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF2075 PF09848.9 CCC69911.1 - 0.073 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.17 CCC69911.1 - 0.11 12.2 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC1 PF03109.16 CCC69912.1 - 7e-36 123.0 0.0 1.3e-35 122.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Abhydrolase_8 PF06259.12 CCC69912.1 - 0.16 11.6 0.0 0.47 10.1 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase CHDCT2 PF08074.11 CCC69913.1 - 0.047 13.9 0.2 0.084 13.0 0.2 1.4 1 0 0 1 1 1 0 CHDCT2 (NUC038) domain Med9 PF07544.13 CCC69913.1 - 0.077 13.1 0.0 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 TcdB_N PF12918.7 CCC69913.1 - 0.13 12.6 0.7 19 5.6 0.1 2.7 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain ANAPC4_WD40 PF12894.7 CCC69914.1 - 2.9e-12 46.7 3.2 0.00076 19.7 0.1 5.0 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCC69914.1 - 3.9e-10 40.2 20.4 0.00023 21.9 0.5 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 CCC69914.1 - 1.8e-08 33.7 0.2 2.1e-05 23.7 0.0 3.2 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein CBS PF00571.28 CCC69915.1 - 2e-25 89.0 4.5 2.4e-11 43.9 0.1 4.3 4 0 0 4 4 4 4 CBS domain PerB PF06590.11 CCC69915.1 - 0.057 13.9 0.0 0.14 12.7 0.0 1.6 2 0 0 2 2 2 0 PerB protein HTH_9 PF08221.11 CCC69915.1 - 0.34 11.0 3.2 1.6 8.8 0.1 3.1 3 0 0 3 3 3 0 RNA polymerase III subunit RPC82 helix-turn-helix domain OPT PF03169.15 CCC69916.1 - 1.2e-156 523.0 18.2 1.4e-156 522.8 18.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4229 PF14012.6 CCC69916.1 - 0.011 15.9 6.7 1 9.5 8.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) Claudin_2 PF13903.6 CCC69916.1 - 1.2 8.9 9.8 0.18 11.6 1.3 3.3 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction DUF4235 PF14019.6 CCC69916.1 - 1.5 9.0 6.6 0.16 12.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) YrhC PF14143.6 CCC69916.1 - 6.5 6.9 5.9 28 4.9 5.9 2.1 1 0 0 1 1 1 0 YrhC-like protein KH_1 PF00013.29 CCC69917.1 - 2.2e-39 133.1 6.8 2e-13 49.9 0.0 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CCC69917.1 - 2.1e-10 40.3 1.4 0.043 13.6 0.0 3.7 3 1 0 3 3 3 3 KH domain KH_4 PF13083.6 CCC69917.1 - 3.3e-08 33.3 2.1 0.002 18.0 0.1 3.5 3 0 0 3 3 3 2 KH domain KH_5 PF13184.6 CCC69917.1 - 0.0016 18.5 2.8 2.4 8.3 0.1 3.6 3 0 0 3 3 3 2 NusA-like KH domain MOEP19 PF16005.5 CCC69917.1 - 0.067 13.2 0.0 2.5 8.2 0.0 2.8 3 0 0 3 3 3 0 KH-like RNA-binding domain SLD3 PF08639.10 CCC69918.1 - 3e-47 161.6 29.0 8.5e-32 110.6 20.5 2.1 1 1 1 2 2 2 2 DNA replication regulator SLD3 Sld3_N PF18523.1 CCC69918.1 - 2.5e-28 98.5 0.6 2.5e-28 98.5 0.6 2.0 2 0 0 2 2 2 1 Sld3 N-terminal domain TAF6_C PF07571.13 CCC69919.1 - 5.5e-30 103.6 0.0 1.1e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 CCC69919.1 - 1.2e-27 95.9 0.3 2.5e-27 94.8 0.3 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 CCC69919.1 - 0.0023 18.3 1.4 0.0067 16.8 0.2 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.14 CCC69919.1 - 0.012 15.4 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family TFIID-31kDa PF02291.15 CCC69919.1 - 0.017 15.2 0.3 0.041 13.9 0.3 1.6 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.6 CCC69919.1 - 0.02 15.3 1.1 0.83 10.1 0.1 3.2 4 0 0 4 4 4 0 CENP-S protein CBFD_NFYB_HMF PF00808.23 CCC69919.1 - 0.033 14.5 1.6 0.086 13.1 0.2 2.4 2 1 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF348 PF03990.14 CCC69919.1 - 0.057 13.2 0.0 0.2 11.4 0.0 2.0 1 0 0 1 1 1 0 G5-linked-Ubiquitin-like domain Sec7_N PF12783.7 CCC69919.1 - 0.17 11.8 5.7 9.1 6.2 0.8 3.3 1 1 2 3 3 3 0 Guanine nucleotide exchange factor in Golgi transport N-terminal DASH_Dad3 PF08656.10 CCC69920.1 - 2.2e-24 85.3 2.4 4.5e-24 84.3 2.4 1.5 1 0 0 1 1 1 1 DASH complex subunit Dad3 DUF4795 PF16043.5 CCC69920.1 - 0.0097 15.5 0.8 0.016 14.8 0.7 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4795) ING PF12998.7 CCC69920.1 - 0.012 16.1 0.4 0.022 15.4 0.2 1.5 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF2951 PF11166.8 CCC69920.1 - 0.028 14.6 0.3 0.043 14.0 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) WD40 PF00400.32 CCC69921.1 - 2.7e-10 40.7 8.8 0.00094 20.0 0.4 6.1 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC69921.1 - 6.5e-10 39.2 0.4 0.006 16.8 0.0 5.2 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCC69921.1 - 0.023 14.6 0.1 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A Hira PF07569.11 CCC69921.1 - 0.082 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split CUE PF02845.16 CCC69922.1 - 4.2e-07 29.6 0.1 1.2e-06 28.1 0.1 1.9 1 0 0 1 1 1 1 CUE domain Clathrin_H_link PF13838.6 CCC69923.1 - 0.0049 16.8 2.2 0.054 13.4 0.3 2.2 2 0 0 2 2 2 2 Clathrin-H-link EF-hand_7 PF13499.6 CCC69925.1 - 1.3e-13 51.2 0.6 8.1e-09 35.8 0.3 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 CCC69925.1 - 3.4e-10 39.6 2.7 1.3e-07 31.4 0.4 3.1 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 CCC69925.1 - 3.7e-09 35.8 5.2 0.00031 20.4 0.1 3.5 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 CCC69925.1 - 8.8e-08 31.2 7.2 0.00096 18.5 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 CCC69925.1 - 9.1e-08 32.3 0.0 0.00054 20.2 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_11 PF08976.11 CCC69925.1 - 0.0027 18.6 0.0 0.0043 17.9 0.0 1.3 1 0 0 1 1 1 1 EF-hand domain EF-hand_14 PF17959.1 CCC69925.1 - 0.0054 17.0 0.1 1.3 9.4 0.0 2.4 2 1 0 2 2 2 1 EF-hand domain FDX-ACB PF03147.14 CCC69925.1 - 0.019 15.3 0.2 0.045 14.2 0.2 1.6 1 1 0 1 1 1 0 Ferredoxin-fold anticodon binding domain EF-hand_5 PF13202.6 CCC69925.1 - 0.3 10.7 4.8 4.2 7.0 0.3 3.0 3 0 0 3 3 3 0 EF hand PhetRS_B1 PF18262.1 CCC69925.1 - 0.34 11.2 2.4 3.9 7.8 0.5 2.5 1 1 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Sugar_tr PF00083.24 CCC69926.1 - 3.6e-85 286.5 21.5 4.4e-85 286.2 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC69926.1 - 8.5e-27 94.0 16.3 8.5e-27 94.0 16.3 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCC69926.1 - 1.7e-09 36.6 3.9 1.7e-09 36.6 3.9 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 CCC69926.1 - 0.00021 20.7 1.7 0.00021 20.7 1.7 2.5 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Ribosomal_L27A PF00828.19 CCC69927.1 - 7.1e-22 78.4 0.1 1.1e-21 77.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A HD_3 PF13023.6 CCC69928.1 - 3.4e-37 127.9 0.1 4.2e-37 127.6 0.1 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CCC69928.1 - 4e-10 39.7 0.1 4.7e-10 39.5 0.1 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CCC69928.1 - 0.00094 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 HD domain Epimerase PF01370.21 CCC69929.1 - 9.5e-18 64.5 0.0 1.3e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 CCC69929.1 - 7.2e-12 45.0 0.0 1.6e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 CCC69929.1 - 9e-12 44.6 0.0 1.1e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 CCC69929.1 - 1.6e-07 31.1 0.3 3.6e-07 29.9 0.3 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CCC69929.1 - 7e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 CCC69929.1 - 8.3e-05 22.1 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 CCC69929.1 - 0.00013 21.2 0.8 0.0011 18.2 0.2 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CCC69929.1 - 0.00022 20.9 0.0 0.0042 16.7 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.17 CCC69929.1 - 0.065 13.8 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent WD40 PF00400.32 CCC69930.1 - 4.9e-19 68.3 15.9 0.00013 22.6 0.6 5.5 5 1 1 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC69930.1 - 4.1e-09 36.6 0.3 0.023 15.0 0.1 3.8 4 0 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Rav1p_C PF12234.8 CCC69930.1 - 0.039 12.4 0.1 0.064 11.6 0.1 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal SNF2_N PF00176.23 CCC69931.1 - 1.3e-75 254.3 0.3 1.3e-75 254.3 0.3 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 CCC69931.1 - 6.8e-37 126.0 0.8 6.8e-37 126.0 0.8 4.1 4 0 0 4 4 4 1 SLIDE HAND PF09110.11 CCC69931.1 - 1.7e-25 89.9 3.7 1.7e-25 89.9 3.7 3.8 4 0 0 4 4 4 1 HAND Helicase_C PF00271.31 CCC69931.1 - 3.5e-20 72.4 0.0 1.9e-19 70.0 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC69931.1 - 7.1e-11 42.4 6.4 1.2e-10 41.6 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCC69931.1 - 4.4e-05 23.3 0.0 9.3e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 CCC69931.1 - 0.00068 19.3 0.1 0.0019 17.8 0.1 1.7 1 0 0 1 1 1 1 DEAD_2 ERCC3_RAD25_C PF16203.5 CCC69931.1 - 0.0031 16.8 2.0 0.0031 16.8 2.0 2.5 3 1 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase AAA_14 PF13173.6 CCC69931.1 - 0.019 15.0 0.1 0.14 12.2 0.1 2.6 1 0 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.31 CCC69931.1 - 0.088 13.0 0.1 7.7 6.8 0.0 3.5 2 1 0 2 2 2 0 Myb-like DNA-binding domain Use1 PF09753.9 CCC69932.1 - 9.8e-11 41.8 0.2 1.2e-10 41.5 0.2 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 Bacillus_HBL PF05791.11 CCC69932.1 - 0.32 10.8 5.2 0.31 10.9 1.2 2.2 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) SMAP PF15477.6 CCC69932.1 - 0.72 10.9 2.5 14 6.8 0.2 2.4 2 0 0 2 2 2 0 Small acidic protein family DHO_dh PF01180.21 CCC69933.1 - 6.7e-94 314.4 0.0 7.6e-94 314.2 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.18 CCC69933.1 - 3.5e-07 29.6 0.0 5.9e-06 25.6 0.0 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Polysacc_deac_1 PF01522.21 CCC69933.1 - 0.0023 17.8 0.0 0.033 14.1 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase NMO PF03060.15 CCC69933.1 - 0.0036 16.8 0.0 0.0056 16.1 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.17 CCC69933.1 - 0.0062 15.7 0.0 0.0092 15.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.25 CCC69933.1 - 0.014 14.4 0.0 0.042 12.9 0.0 1.6 1 1 1 2 2 2 0 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 CCC69933.1 - 0.034 13.6 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein adh_short PF00106.25 CCC69934.1 - 2.2e-15 56.6 0.0 2.4e-14 53.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCC69934.1 - 7.7e-06 25.6 0.0 6.7e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCC69934.1 - 1.2e-05 25.3 0.0 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CCC69934.1 - 0.00054 19.5 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 CCC69934.1 - 0.087 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 CCC69934.1 - 0.23 10.5 0.1 2.5 7.1 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.25 CCC69935.1 - 5.1e-17 62.0 0.0 6.1e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCC69935.1 - 9.3e-08 31.9 0.0 1.9e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCC69935.1 - 1.6e-06 28.1 0.0 2.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 CCC69935.1 - 5.6e-05 22.7 0.0 9.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CCC69935.1 - 0.00014 21.4 0.0 0.00019 21.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 CCC69935.1 - 0.011 15.7 0.1 0.02 14.9 0.1 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Papilloma_E5 PF03025.14 CCC69936.1 - 0.22 11.7 0.3 0.22 11.7 0.3 2.6 2 1 0 2 2 2 0 Papillomavirus E5 RCC1 PF00415.18 CCC69937.1 - 2.1e-64 214.0 0.4 4.3e-09 36.9 0.2 7.4 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCC69937.1 - 2.3e-35 119.7 15.6 9.3e-06 25.3 0.3 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Homeobox_KN PF05920.11 CCC69938.1 - 3.2e-17 62.1 0.3 6e-17 61.3 0.3 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 CCC69938.1 - 0.00027 20.7 0.1 0.0006 19.6 0.1 1.5 1 0 0 1 1 1 1 Homeodomain RRM_1 PF00076.22 CCC69939.1 - 4.7e-13 48.7 0.1 7.9e-13 48.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.29 CCC69940.1 - 8.4e-10 38.4 5.6 1.6e-09 37.5 5.6 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CCC69940.1 - 0.056 13.0 4.5 0.091 12.3 4.5 1.4 1 0 0 1 1 1 0 PHD-finger Ribosomal_S18 PF01084.20 CCC69940.1 - 0.085 13.1 1.1 0.5 10.6 0.8 2.4 2 0 0 2 2 2 0 Ribosomal protein S18 UCH_1 PF13423.6 CCC69941.1 - 5.2e-69 233.3 12.2 8.3e-69 232.6 12.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 CCC69941.1 - 2.7e-22 80.1 0.0 8e-22 78.5 0.0 1.9 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 CCC69941.1 - 4.6e-07 29.6 7.6 4.6e-07 29.6 7.6 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ANAPC4_WD40 PF12894.7 CCC69941.1 - 0.007 16.6 0.0 0.096 13.0 0.0 2.7 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Spc7 PF08317.11 CCC69942.1 - 1e-54 185.5 9.7 2.2e-54 184.5 9.7 1.5 1 0 0 1 1 1 1 Spc7 kinetochore protein Osmo_CC PF08946.10 CCC69942.1 - 0.14 12.4 3.3 0.46 10.8 0.6 3.4 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF1359 PF07097.11 CCC69942.1 - 2.7 8.3 9.0 2.1 8.7 3.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1359) JIP_LZII PF16471.5 CCC69942.1 - 3.9 7.7 8.8 48 4.2 0.1 3.6 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II Nucleoporin2 PF04096.14 CCC69943.1 - 1.1e-45 155.4 0.0 2.5e-45 154.2 0.0 1.7 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nup96 PF12110.8 CCC69943.1 - 2.4e-33 115.5 0.1 2.7e-32 112.1 0.1 2.2 1 1 0 1 1 1 1 Nuclear protein 96 Nucleoporin_FG PF13634.6 CCC69943.1 - 1.7e-09 38.4 66.3 1.1e-08 35.8 37.5 4.8 2 1 2 4 4 4 3 Nucleoporin FG repeat region ParA PF10609.9 CCC69944.1 - 2.3e-92 308.9 0.0 2.6e-92 308.7 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CCC69944.1 - 4.5e-10 39.7 0.0 8.3e-10 38.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CCC69944.1 - 1.1e-06 28.7 0.6 4.2e-05 23.5 0.6 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CCC69944.1 - 6.3e-05 22.4 0.0 9.8e-05 21.8 0.0 1.3 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CCC69944.1 - 0.001 18.4 2.6 0.0038 16.5 0.4 2.5 1 1 2 3 3 3 1 Anion-transporting ATPase RsgA_GTPase PF03193.16 CCC69944.1 - 0.015 15.2 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase CBP_BcsQ PF06564.12 CCC69944.1 - 0.018 14.5 0.1 0.029 13.9 0.1 1.5 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ TF_Zn_Ribbon PF08271.12 CCC69944.1 - 0.029 13.9 0.2 0.073 12.6 0.2 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding AAA_26 PF13500.6 CCC69944.1 - 0.034 14.0 0.0 0.34 10.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCC69944.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 CCC69944.1 - 0.095 12.6 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain SYCE1 PF15233.6 CCC69945.1 - 0.0031 17.6 2.3 0.0096 16.0 2.3 1.9 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 MF_alpha PF04648.12 CCC69946.1 - 1.4e-34 117.0 61.0 1.2e-06 28.5 5.8 5.2 5 0 0 5 5 5 5 Yeast mating factor alpha hormone MF_alpha_N PF05436.11 CCC69946.1 - 4.5e-34 116.2 0.9 6.1e-34 115.8 0.9 1.2 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus Apidaecin PF00807.17 CCC69946.1 - 0.045 13.9 16.0 4.4 7.5 0.3 5.1 5 0 0 5 5 5 0 Apidaecin UQ_con PF00179.26 CCC69947.1 - 7.6e-18 64.5 0.0 8.3e-18 64.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCC69947.1 - 0.0068 16.7 0.0 0.0071 16.6 0.0 1.2 1 0 0 1 1 1 1 RWD domain MAD PF05557.13 CCC69948.1 - 8.6e-36 123.5 78.2 1.1e-35 123.2 78.2 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Pox_A_type_inc PF04508.12 CCC69948.1 - 0.23 11.4 5.6 1.7e+02 2.3 0.1 5.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat SNase PF00565.17 CCC69949.1 - 2.1e-26 92.5 0.0 3.3e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Pkinase PF00069.25 CCC69950.1 - 5.1e-24 85.0 0.5 8.6e-24 84.3 0.5 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69950.1 - 1.2e-12 47.7 0.0 2.1e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase MINDY_DUB PF04424.13 CCC69951.1 - 2.9e-28 98.2 1.0 4.6e-28 97.6 0.3 1.7 2 0 0 2 2 2 1 MINDY deubiquitinase Lipoprotein_17 PF04200.12 CCC69952.1 - 0.049 14.0 2.8 0.081 13.3 2.8 1.6 1 1 0 1 1 1 0 Lipoprotein associated domain MPC PF03650.13 CCC69953.1 - 1.4e-41 141.1 0.0 1.7e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers KxDL PF10241.9 CCC69954.1 - 1.2e-22 80.0 2.3 2.4e-22 79.0 2.3 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein DEAD PF00270.29 CCC69955.1 - 1.3e-51 174.9 0.0 3.2e-51 173.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC69955.1 - 4.8e-36 123.5 0.1 1.7e-31 108.9 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 CCC69955.1 - 0.00041 19.6 0.0 0.00041 19.6 0.0 2.3 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 CCC69955.1 - 0.00071 19.0 14.6 0.0036 16.7 0.0 2.6 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit UTP25 PF06862.12 CCC69955.1 - 0.04 12.7 0.1 0.04 12.7 0.1 3.4 3 1 1 4 4 4 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_22 PF13401.6 CCC69955.1 - 0.14 12.4 1.1 1.6 9.0 1.1 2.6 1 1 0 1 1 1 0 AAA domain AP3D1 PF06375.11 CCC69955.1 - 0.76 10.0 21.9 1.7 8.9 21.9 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 DMP1 PF07263.11 CCC69955.1 - 0.9 8.4 17.7 1.2 7.9 17.7 1.1 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) Vfa1 PF08432.10 CCC69955.1 - 5 7.4 22.4 11 6.3 22.4 1.6 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.12 CCC69955.1 - 8.4 5.7 19.1 14 4.9 19.1 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger AA_permease_2 PF13520.6 CCC69956.1 - 3.5e-49 167.8 48.0 4.1e-49 167.6 48.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCC69956.1 - 1.5e-20 73.2 39.1 2e-20 72.8 39.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2207 PF09972.9 CCC69956.1 - 0.6 8.8 0.0 0.6 8.8 0.0 3.6 3 2 1 4 4 4 0 Predicted membrane protein (DUF2207) DUF1129 PF06570.11 CCC69956.1 - 3.5 7.1 9.2 1.8 8.0 4.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Ribosomal_L30_N PF08079.12 CCC69957.1 - 3.7e-21 75.2 17.2 6.1e-21 74.5 17.2 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 CCC69957.1 - 1.8e-19 69.3 4.0 2.7e-19 68.8 2.9 1.9 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e MPS2 PF17060.5 CCC69958.1 - 2.3e-42 145.6 10.9 4.2e-38 131.6 10.9 3.0 1 1 0 1 1 1 1 Monopolar spindle protein 2 DUF2508 PF10704.9 CCC69958.1 - 1.5 9.0 5.7 0.56 10.4 1.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2508) DUF4407 PF14362.6 CCC69958.1 - 4.3 6.6 7.6 12 5.2 6.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HSF_DNA-bind PF00447.17 CCC69959.1 - 1.1e-29 102.9 1.0 1.1e-29 102.9 1.0 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding AFT PF08731.11 CCC69960.1 - 3e-47 159.6 4.0 1.5e-46 157.3 4.0 2.3 1 0 0 1 1 1 1 Transcription factor AFT DBD_Tnp_Mut PF03108.15 CCC69960.1 - 0.036 14.1 0.3 5.8 7.0 0.0 2.4 2 0 0 2 2 2 0 MuDR family transposase RNA_POL_M_15KD PF02150.16 CCC69961.1 - 1.7e-17 63.0 4.1 1.7e-17 63.0 4.1 2.7 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 CCC69961.1 - 3.5e-13 49.1 2.8 3.5e-13 49.1 2.8 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) DUF2387 PF09526.10 CCC69961.1 - 0.0013 18.8 4.2 0.52 10.5 0.6 2.4 2 1 0 2 2 2 2 Probable metal-binding protein (DUF2387) zf-UBP PF02148.19 CCC69961.1 - 0.03 14.6 3.7 0.54 10.6 0.3 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein DZR PF12773.7 CCC69961.1 - 0.064 13.3 7.7 1.5 8.9 0.4 2.5 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1 PF03811.13 CCC69961.1 - 0.3 10.8 0.2 0.3 10.8 0.2 3.6 5 0 0 5 5 5 0 InsA N-terminal domain Lar_restr_allev PF14354.6 CCC69961.1 - 0.31 11.5 0.3 0.31 11.5 0.3 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 CCC69961.1 - 0.31 11.0 10.9 2.1 8.4 2.8 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-CSL PF05207.13 CCC69961.1 - 0.35 10.6 4.4 5.1 6.9 0.3 2.3 2 0 0 2 2 2 0 CSL zinc finger Rubredoxin PF00301.20 CCC69961.1 - 1 9.5 5.4 19 5.4 0.2 3.3 4 0 0 4 4 4 0 Rubredoxin zinc_ribbon_10 PF10058.9 CCC69961.1 - 1.4 8.7 7.1 9 6.1 0.4 2.6 2 1 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein RPA_interact_C PF14768.6 CCC69961.1 - 2.2 8.9 8.9 3.4 8.3 0.8 2.6 2 1 0 2 2 2 0 Replication protein A interacting C-terminal Nudix_N_2 PF14803.6 CCC69961.1 - 2.3 8.2 11.1 0.89 9.5 1.1 3.2 3 0 0 3 3 3 0 Nudix N-terminal Ribosomal_L12 PF00542.19 CCC69962.1 - 7.6e-22 77.4 8.6 7.6e-22 77.4 8.6 1.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 CCC69962.1 - 9.5e-13 47.6 0.8 9.5e-13 47.6 0.8 3.0 3 0 0 3 3 3 2 Ribosomal protein L7/L12 dimerisation domain Ribosomal_60s PF00428.19 CCC69962.1 - 4.8 7.8 13.3 0.058 14.0 3.9 2.4 1 1 2 3 3 3 0 60s Acidic ribosomal protein Pkinase PF00069.25 CCC69963.1 - 3e-24 85.8 0.0 6e-24 84.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC69963.1 - 6.2e-15 55.2 0.0 1e-14 54.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC69963.1 - 8.6e-08 31.4 0.0 8.6e-08 31.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 CCC69963.1 - 0.024 14.6 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 Phosphotransferase enzyme family GDC-P PF02347.16 CCC69964.1 - 5.3e-192 638.4 0.0 9.9e-183 607.8 0.0 2.5 2 1 0 2 2 2 2 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.20 CCC69964.1 - 0.00011 20.9 0.0 0.00019 20.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ribosomal_S17 PF00366.20 CCC69965.1 - 6.8e-23 80.6 0.5 6.8e-23 80.6 0.5 1.9 2 0 0 2 2 2 1 Ribosomal protein S17 CPSase_L_D3 PF02787.19 CCC69965.1 - 2.5 8.5 6.4 1.2 9.5 1.1 2.4 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Glyco_hydro_16 PF00722.21 CCC69966.1 - 4.4e-21 75.2 1.6 4.4e-21 75.2 1.6 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 RINGv PF12906.7 CCC69967.1 - 0.0002 21.4 5.2 0.00041 20.4 5.2 1.5 1 0 0 1 1 1 1 RING-variant domain zinc-ribbons_6 PF07191.12 CCC69967.1 - 0.94 9.5 6.3 7.8 6.6 1.4 2.2 2 0 0 2 2 2 0 zinc-ribbons zf-RING_2 PF13639.6 CCC69967.1 - 1.5 9.2 11.6 0.31 11.4 6.6 2.1 2 0 0 2 2 2 0 Ring finger domain HSP90 PF00183.18 CCC69968.1 - 8.4e-221 734.3 32.6 1.2e-220 733.8 32.6 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 CCC69968.1 - 2.8e-14 53.6 0.0 5.2e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 CCC69968.1 - 9.4e-10 38.5 0.0 2.7e-09 37.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ubiq-assoc PF09145.10 CCC69968.1 - 0.079 13.0 0.2 2.6 8.1 0.0 2.9 3 0 0 3 3 3 0 Ubiquitin-associated RTP1_C1 PF10363.9 CCC69969.1 - 5.3e-31 107.1 2.6 1.1e-30 106.0 0.3 2.9 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 CCC69969.1 - 2.5e-09 36.6 3.6 7e-09 35.2 3.6 1.9 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 Mad3_BUB1_I PF08311.12 CCC69969.1 - 0.71 9.9 3.3 3.7 7.5 0.1 3.6 3 0 0 3 3 3 0 Mad3/BUB1 homology region 1 DUF3788 PF12663.7 CCC69970.1 - 0.008 16.1 0.9 0.12 12.3 0.2 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3788) Syntaxin PF00804.25 CCC69971.1 - 5.7e-21 75.1 23.3 1.1e-20 74.2 22.2 1.9 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 CCC69971.1 - 2.4e-11 43.4 2.0 1e-10 41.4 2.0 2.2 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 CCC69971.1 - 0.00023 20.9 1.4 0.00023 20.9 1.4 2.4 2 0 0 2 2 2 1 Synaptobrevin SLATT_5 PF18160.1 CCC69971.1 - 0.04 13.3 0.0 0.04 13.3 0.0 3.0 2 1 1 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 T2SSF PF00482.23 CCC69971.1 - 0.079 12.9 1.7 0.23 11.4 1.7 1.8 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF2730 PF10805.8 CCC69971.1 - 0.086 12.9 5.2 0.33 11.1 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) LMBR1 PF04791.16 CCC69971.1 - 0.12 11.3 7.8 0.16 10.8 7.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein RNase_3_N PF18497.1 CCC69971.1 - 0.18 12.0 6.4 0.18 12.0 0.1 2.6 3 0 0 3 3 3 0 Ribonuclease III N-terminal domain Allexi_40kDa PF05549.11 CCC69971.1 - 0.36 10.3 12.9 0.14 11.7 3.6 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein UPF0258 PF06789.12 CCC69971.1 - 0.4 10.8 6.4 1 9.5 1.3 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0258) WDCP PF15390.6 CCC69971.1 - 0.53 8.6 12.7 0.65 8.3 12.7 1.2 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family MecA_N PF05223.11 CCC69971.1 - 0.54 10.5 6.9 0.25 11.6 2.1 2.4 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain FUSC PF04632.12 CCC69971.1 - 1.8 7.0 10.3 0.2 10.2 0.9 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family BLOC1_2 PF10046.9 CCC69971.1 - 2.6 8.4 19.2 1.2 9.5 2.2 3.6 2 2 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SlyX PF04102.12 CCC69971.1 - 4.5 8.0 18.2 0.74 10.5 3.6 3.3 2 1 1 3 3 3 0 SlyX DUF1664 PF07889.12 CCC69971.1 - 6.4 6.8 10.7 4.4 7.4 1.8 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) zf-C2H2 PF00096.26 CCC69972.1 - 5.8e-08 32.8 13.1 0.00022 21.5 3.2 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC69972.1 - 3.6e-07 30.3 2.8 3.6e-07 30.3 2.8 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC69972.1 - 0.00033 21.3 10.5 0.024 15.5 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HE PF16278.5 CCC69972.1 - 0.049 14.1 2.5 0.18 12.3 2.5 2.0 1 0 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger zf-met PF12874.7 CCC69972.1 - 2.8 8.5 5.6 3.5 8.1 0.5 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF1586 PF07625.11 CCC69972.1 - 3.7 7.7 4.8 0.42 10.7 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) zf-H2C2_5 PF13909.6 CCC69972.1 - 3.8 7.4 6.9 3.3 7.5 1.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc-finger domain mRNA_triPase PF02940.15 CCC69974.1 - 4.6e-12 46.1 1.5 1.7e-09 37.8 1.2 2.3 1 1 1 2 2 2 2 mRNA capping enzyme, beta chain CENP-B_dimeris PF09026.10 CCC69975.1 - 0.0079 16.6 0.7 0.0079 16.6 0.7 3.7 3 1 1 4 4 4 1 Centromere protein B dimerisation domain Pept_S41_N PF18294.1 CCC69975.1 - 0.16 11.9 7.3 1.2 9.1 0.3 3.4 3 0 0 3 3 3 0 Peptidase S41 N-terminal domain ABC_tran PF00005.27 CCC69976.1 - 2.7e-49 167.2 0.0 1e-25 90.8 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 CCC69976.1 - 1.1e-14 54.9 0.7 0.013 15.4 0.0 4.6 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCC69976.1 - 4.8e-13 49.1 0.0 0.00091 18.7 0.0 3.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.24 CCC69976.1 - 5.3e-10 39.1 2.7 1.3e-09 37.8 2.7 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_23 PF13476.6 CCC69976.1 - 1.1e-08 35.9 0.6 0.0077 16.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 CCC69976.1 - 3.5e-07 29.9 0.1 0.027 14.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CCC69976.1 - 6.2e-07 29.5 0.0 0.018 15.1 0.0 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCC69976.1 - 1.1e-06 28.6 0.1 0.018 15.0 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 CCC69976.1 - 5.2e-05 23.5 0.0 0.66 10.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.6 CCC69976.1 - 9.7e-05 22.2 0.1 1.2 8.8 0.0 3.5 3 1 1 4 4 3 2 AAA ATPase domain DUF87 PF01935.17 CCC69976.1 - 0.00015 22.0 0.9 0.047 13.8 0.0 3.5 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_16 PF13191.6 CCC69976.1 - 0.00018 22.0 0.3 0.15 12.4 0.0 3.6 3 1 0 3 3 2 1 AAA ATPase domain AAA_28 PF13521.6 CCC69976.1 - 0.00021 21.6 0.0 0.42 10.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 CCC69976.1 - 0.00034 19.7 0.1 0.8 8.6 0.0 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 CCC69976.1 - 0.00052 20.6 0.0 0.71 10.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 CCC69976.1 - 0.00059 20.2 0.0 1.6 9.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 CCC69976.1 - 0.0022 17.8 0.2 3.3 7.4 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_27 PF13514.6 CCC69976.1 - 0.0027 17.4 0.0 1.1 8.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 CCC69976.1 - 0.0029 18.0 0.0 4.7 7.6 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 CCC69976.1 - 0.0032 17.6 0.0 4.9 7.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCC69976.1 - 0.0044 17.0 0.1 2.7 7.9 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Dynamin_N PF00350.23 CCC69976.1 - 0.0046 17.0 0.1 0.4 10.7 0.0 3.0 2 1 0 2 2 2 1 Dynamin family AAA_13 PF13166.6 CCC69976.1 - 0.0097 14.6 0.0 1.4 7.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CCC69976.1 - 0.019 15.0 0.0 6.2 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 CCC69976.1 - 0.02 14.1 0.2 3 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 CCC69976.1 - 0.042 14.1 0.0 13 6.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 CCC69976.1 - 0.046 13.6 0.1 7.4 6.4 0.1 2.9 3 0 0 3 3 3 0 NTPase MukB PF04310.12 CCC69976.1 - 0.049 13.4 0.1 7.7 6.2 0.0 2.8 3 0 0 3 3 3 0 MukB N-terminal AAA_24 PF13479.6 CCC69976.1 - 0.052 13.3 0.1 2.7 7.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 CCC69976.1 - 0.061 12.5 0.1 2 7.5 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain CLP1_P PF16575.5 CCC69976.1 - 0.072 12.9 0.1 6.7 6.5 0.0 2.8 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 CCC69976.1 - 0.078 12.2 0.1 8.4 5.6 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin TsaE PF02367.17 CCC69976.1 - 0.098 12.7 0.2 13 5.8 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Thymidylate_kin PF02223.17 CCC69976.1 - 0.12 12.0 0.2 1.2 8.8 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase cobW PF02492.19 CCC69976.1 - 0.13 11.9 0.1 35 3.9 0.0 3.3 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ABC_tran_Xtn PF12848.7 CCC69976.1 - 6 7.0 8.6 0.14 12.2 0.5 2.6 2 0 0 2 2 1 0 ABC transporter Polysacc_synt_4 PF04669.13 CCC69977.1 - 1.6e-19 70.2 1.6 5.1e-18 65.3 1.6 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis Cation_efflux PF01545.21 CCC69978.1 - 7.5e-45 153.1 11.7 1.1e-44 152.6 11.7 1.3 1 0 0 1 1 1 1 Cation efflux family ARID PF01388.21 CCC69979.1 - 8e-18 64.9 1.0 4.8e-17 62.4 0.0 3.0 3 0 0 3 3 3 1 ARID/BRIGHT DNA binding domain JmjC PF02373.22 CCC69979.1 - 4.9e-13 49.5 0.2 6.6e-08 33.0 0.1 3.2 1 1 1 2 2 2 2 JmjC domain, hydroxylase PHD PF00628.29 CCC69979.1 - 5e-07 29.5 5.7 1.2e-06 28.3 5.7 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CCC69979.1 - 0.05 13.9 1.9 0.15 12.4 1.9 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.22 CCC69979.1 - 0.27 11.1 2.2 0.78 9.7 2.2 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 CCC69979.1 - 0.48 10.4 3.8 3 7.8 3.8 2.4 1 1 1 2 2 2 0 Putative zinc-RING and/or ribbon Ribosomal_L19 PF01245.20 CCC69980.1 - 4.2e-10 39.6 0.3 6.1e-10 39.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Inhibitor_I34 PF10466.9 CCC69981.1 - 1.6e-28 99.1 13.1 2.6e-28 98.4 13.1 1.3 1 0 0 1 1 1 1 Saccharopepsin inhibitor I34 DUF3810 PF12725.7 CCC69981.1 - 0.44 9.8 3.0 0.45 9.8 3.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) YtxH PF12732.7 CCC69981.1 - 8.2 7.0 9.7 1.4e+02 3.1 9.7 2.0 1 1 0 1 1 1 0 YtxH-like protein DUF4573 PF15140.6 CCC69982.1 - 1.1e-13 51.4 0.0 0.32 10.8 0.0 6.1 1 1 6 7 7 7 6 Domain of unknown function (DUF4573) GCR1_C PF12550.8 CCC69983.1 - 3.8e-22 78.4 1.0 1e-21 77.0 1.0 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes YL1 PF05764.13 CCC69983.1 - 1.2 9.2 22.7 0.26 11.4 16.9 2.3 2 0 0 2 2 2 0 YL1 nuclear protein BUD22 PF09073.10 CCC69983.1 - 2.7 7.2 27.5 0.13 11.6 21.8 1.6 2 0 0 2 2 2 0 BUD22 Nop14 PF04147.12 CCC69983.1 - 3.5 5.7 28.3 0.026 12.8 19.3 1.8 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 CCC69983.1 - 6 5.0 16.3 9.7 4.3 16.3 1.3 1 0 0 1 1 1 0 CDC45-like protein TRP PF06011.12 CCC69984.1 - 7.8e-156 519.1 38.4 1.2e-155 518.4 38.4 1.3 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.6 CCC69984.1 - 8.7e-41 139.5 0.5 1.4e-40 138.9 0.5 1.4 1 0 0 1 1 1 1 ML-like domain TMEMspv1-c74-12 PF11044.8 CCC69984.1 - 0.0036 17.2 1.9 0.0053 16.7 0.0 2.3 2 0 0 2 2 2 1 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF2721 PF11026.8 CCC69984.1 - 0.019 14.9 0.1 0.019 14.9 0.1 4.8 4 1 1 5 5 5 0 Protein of unknown function (DUF2721) CH PF00307.31 CCC69985.1 - 0.033 14.4 0.1 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Calponin homology (CH) domain Coatomer_WDAD PF04053.14 CCC69986.1 - 1.9e-167 557.8 2.7 2.5e-167 557.4 2.7 1.1 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 CCC69986.1 - 3.8e-18 65.5 3.8 2.3e-06 28.2 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 CCC69986.1 - 0.0071 15.0 0.6 2.4 6.7 0.1 3.3 1 1 2 3 3 3 2 Nucleoporin Nup120/160 TPR_2 PF07719.17 CCC69986.1 - 0.11 12.7 2.6 11 6.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat FtsJ PF01728.19 CCC69987.1 - 3.7e-50 170.5 0.0 4.8e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CCC69987.1 - 0.0023 17.8 0.0 0.0076 16.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC69987.1 - 0.018 14.8 0.0 7.1 6.4 0.1 2.5 2 1 0 2 2 2 0 Methyltransferase domain Cyclin PF08613.11 CCC69988.1 - 1.2e-18 68.0 2.1 1.2e-18 68.0 0.3 1.9 2 0 0 2 2 2 1 Cyclin Ku_PK_bind PF08785.11 CCC69988.1 - 3.8e-05 23.8 0.4 0.00036 20.7 0.3 2.2 2 0 0 2 2 2 1 Ku C terminal domain like Cyclin_N PF00134.23 CCC69988.1 - 0.044 13.5 0.4 0.093 12.5 0.4 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain WAC_Acf1_DNA_bd PF10537.9 CCC69989.1 - 1.4e-35 121.8 1.3 3.4e-35 120.6 0.3 2.3 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 CCC69989.1 - 1.3e-11 44.8 0.1 1.3e-11 44.8 0.1 3.9 3 1 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 CCC69989.1 - 1.5e-10 41.2 0.1 9.1e-10 38.7 0.0 2.4 3 0 0 3 3 3 1 DDT domain WHIM1 PF15612.6 CCC69989.1 - 0.0044 16.5 0.1 0.016 14.7 0.1 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 BAH PF01426.18 CCC69990.1 - 1.1e-19 70.4 0.2 4.3e-19 68.6 0.2 2.1 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.6 CCC69990.1 - 1.1e-14 54.5 28.4 5.9e-12 45.7 4.2 4.3 4 0 0 4 4 4 3 PHD-zinc-finger like domain PHD PF00628.29 CCC69990.1 - 2.4e-13 49.7 53.3 9.4e-07 28.6 14.2 5.4 4 1 1 5 5 5 3 PHD-finger zf-HC5HC2H PF13771.6 CCC69990.1 - 2.2e-08 34.3 34.9 2.9e-07 30.6 1.3 4.6 4 0 0 4 4 4 3 PHD-like zinc-binding domain C1_1 PF00130.22 CCC69990.1 - 4.9e-05 23.1 4.7 4.9e-05 23.1 4.7 6.3 7 0 0 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 CCC69990.1 - 5.3e-05 22.7 22.8 0.0002 20.8 4.5 4.7 3 1 0 3 3 3 2 PHD-finger Myb_DNA-binding PF00249.31 CCC69990.1 - 0.031 14.4 0.0 0.087 13.0 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain RusA PF05866.11 CCC69990.1 - 4.1 8.0 8.6 0.18 12.3 0.6 2.7 2 0 0 2 2 2 0 Endodeoxyribonuclease RusA mRNA_cap_enzyme PF01331.19 CCC69991.1 - 1.6e-64 217.3 0.2 2.9e-64 216.5 0.1 1.5 2 0 0 2 2 2 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 CCC69991.1 - 9.4e-33 113.1 0.3 1.9e-32 112.1 0.3 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.21 CCC69991.1 - 6e-08 32.6 0.0 0.00066 19.4 0.0 2.7 1 1 1 2 2 2 2 ATP dependent DNA ligase domain DAP3 PF10236.9 CCC69992.1 - 4.9e-83 278.9 1.2 6.1e-83 278.6 1.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.6 CCC69992.1 - 0.00018 21.9 0.0 0.00033 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 CCC69992.1 - 0.0056 16.6 0.0 0.031 14.2 0.0 2.3 3 0 0 3 3 3 1 NACHT domain AAA_22 PF13401.6 CCC69992.1 - 0.0067 16.7 0.1 0.033 14.5 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCC69992.1 - 0.0072 16.9 0.0 0.017 15.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 CCC69992.1 - 0.013 15.4 0.2 0.12 12.3 0.0 2.6 3 0 0 3 3 3 0 NTPase AAA_7 PF12775.7 CCC69992.1 - 0.032 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_30 PF13604.6 CCC69992.1 - 0.039 13.7 0.0 0.073 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 CCC69992.1 - 0.054 12.7 0.0 0.14 11.3 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_19 PF13245.6 CCC69992.1 - 0.071 13.4 0.0 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CCC69992.1 - 0.072 13.1 0.1 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 CCC69992.1 - 0.082 13.3 0.0 0.2 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CCC69992.1 - 0.096 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein PseudoU_synth_1 PF01416.20 CCC69993.1 - 1.3e-15 57.7 0.0 4.6e-10 39.9 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase DEAD PF00270.29 CCC69994.1 - 1.2e-33 116.4 0.2 2.5e-33 115.3 0.2 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC69994.1 - 1e-19 70.9 0.8 1.1e-18 67.6 0.1 2.8 2 1 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC69994.1 - 3.1e-10 40.3 0.4 1.3e-09 38.3 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCC69994.1 - 0.016 15.5 0.4 0.098 12.9 0.4 2.3 1 1 0 1 1 1 0 AAA domain EF-hand_11 PF08976.11 CCC69994.1 - 0.049 14.5 0.2 4.4 8.2 0.1 2.5 2 0 0 2 2 2 0 EF-hand domain SWI2_SNF2 PF18766.1 CCC69994.1 - 0.1 12.2 0.1 0.24 11.1 0.1 1.6 1 1 0 1 1 1 0 SWI2/SNF2 ATPase Glycos_transf_1 PF00534.20 CCC69995.1 - 1.9e-30 105.7 0.0 3e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCC69995.1 - 1.4e-14 54.5 0.0 2.2e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 CCC69995.1 - 1.7e-09 38.2 0.0 5.6e-09 36.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 CCC69995.1 - 0.051 13.6 0.6 4.9 7.1 0.6 2.6 1 1 0 1 1 1 0 ALG11 mannosyltransferase N-terminus Toxin_22 PF08092.11 CCC69995.1 - 0.2 11.8 0.3 0.43 10.7 0.3 1.6 1 0 0 1 1 1 0 Magi peptide toxin family SCA7 PF08313.12 CCC69996.1 - 3.3e-29 100.6 0.4 3.3e-29 100.6 0.4 2.1 2 0 0 2 2 2 1 SCA7, zinc-binding domain zf_C2H2_13 PF18508.1 CCC69996.1 - 1.3e-18 66.3 0.4 2.8e-18 65.2 0.4 1.6 1 0 0 1 1 1 1 Zinc finger domain Sigma70_ner PF04546.13 CCC69996.1 - 0.0036 17.2 9.1 0.0036 17.2 9.1 3.5 3 0 0 3 3 3 1 Sigma-70, non-essential region CDC27 PF09507.10 CCC69996.1 - 0.0038 16.7 14.5 0.0038 16.7 14.5 3.1 3 0 0 3 3 3 1 DNA polymerase subunit Cdc27 Bud13 PF09736.9 CCC69996.1 - 0.0046 17.3 8.4 0.0046 17.3 8.4 3.8 3 1 1 4 4 4 1 Pre-mRNA-splicing factor of RES complex NUDIX PF00293.28 CCC69998.1 - 6.9e-14 52.0 0.0 1.3e-13 51.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.11 CCC69998.1 - 0.0003 20.4 0.4 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain DUF3323 PF11796.8 CCC69998.1 - 0.041 13.8 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) IBR PF01485.21 CCC69998.1 - 0.043 14.0 0.9 0.043 14.0 0.9 1.9 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Helicase_Sgs1 PF11408.8 CCC69999.1 - 1.3e-26 92.5 0.1 3.4e-26 91.1 0.1 1.8 1 0 0 1 1 1 1 Sgs1 RecQ helicase RQC PF09382.10 CCC69999.1 - 9.9e-26 89.8 0.2 2.3e-25 88.6 0.2 1.6 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 CCC69999.1 - 2e-23 82.9 0.2 7.6e-18 64.9 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 CCC69999.1 - 6.2e-21 74.9 0.1 3.3e-20 72.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CCC69999.1 - 7.7e-16 58.6 10.0 2.5e-15 56.9 10.0 2.0 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 CCC69999.1 - 5.6e-05 23.2 3.8 0.00037 20.5 0.0 3.9 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HRDC PF00570.23 CCC69999.1 - 0.00041 20.3 0.0 0.00099 19.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Gluconate_2-dh3 PF13618.6 CCC69999.1 - 0.18 12.0 0.7 2.3 8.4 0.7 2.7 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 AAA_34 PF13872.6 CCC69999.1 - 0.53 9.1 2.9 1 8.2 0.4 2.5 3 0 0 3 3 3 0 P-loop containing NTP hydrolase pore-1 MetOD2 PF18548.1 CCC69999.1 - 3.3 7.9 6.1 1.5 9.0 2.3 2.5 2 0 0 2 2 2 0 Metanogen output domain 2 Fungal_trans PF04082.18 CCC70000.1 - 7.9e-24 84.1 6.6 2.5e-23 82.5 6.6 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC70000.1 - 1.1e-09 38.2 13.8 2.1e-09 37.4 13.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.13 CCC70000.1 - 7.1e-08 32.5 1.6 2.2e-07 30.9 1.6 1.9 1 0 0 1 1 1 1 Gal4-like dimerisation domain RabGAP-TBC PF00566.18 CCC70002.1 - 1.8e-16 60.4 1.4 1.8e-16 60.4 1.4 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain TRAF_BIRC3_bd PF16673.5 CCC70002.1 - 0.034 13.9 5.9 0.031 14.1 1.1 2.9 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Cnn_1N PF07989.11 CCC70002.1 - 0.11 12.6 13.1 0.076 13.2 6.2 3.2 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 SOGA PF11365.8 CCC70002.1 - 5.7 8.1 13.6 5.3 8.2 4.4 3.8 2 1 1 3 3 3 0 Protein SOGA Ribosomal_L28 PF00830.19 CCC70003.1 - 3.2e-19 68.9 1.6 3.2e-19 68.9 1.6 2.0 2 0 0 2 2 2 1 Ribosomal L28 family Ribosomal_L36e PF01158.18 CCC70004.1 - 9.8e-37 125.1 4.4 1.1e-36 124.9 4.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.6 CCC70004.1 - 0.035 14.2 0.1 0.043 14.0 0.1 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain MTCP1 PF08991.10 CCC70005.1 - 1.3e-20 73.3 3.8 1.5e-20 73.1 3.8 1.1 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type Oxidored_FMN PF00724.20 CCC70007.1 - 1.7e-107 359.6 0.0 2e-107 359.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glyco_hydro_63 PF03200.16 CCC70008.1 - 5.3e-06 25.5 14.0 5.9e-05 22.0 0.6 4.6 5 1 0 5 5 5 2 Glycosyl hydrolase family 63 C-terminal domain V-SNARE PF05008.15 CCC70009.1 - 3.5e-19 69.0 2.7 3.5e-19 69.0 2.7 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 CCC70009.1 - 3.7e-19 68.8 4.7 8.5e-19 67.6 2.8 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Use1 PF09753.9 CCC70009.1 - 0.002 17.9 3.7 0.0029 17.4 3.7 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Sec20 PF03908.13 CCC70009.1 - 0.048 13.6 0.7 0.048 13.6 0.7 2.2 2 1 1 3 3 3 0 Sec20 YqjK PF13997.6 CCC70009.1 - 0.13 12.6 1.2 1.8 8.9 0.0 2.6 2 0 0 2 2 2 0 YqjK-like protein T3SS_basalb_I PF17001.5 CCC70009.1 - 0.28 11.8 3.6 1 10.0 0.2 2.7 1 1 1 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI YtxH PF12732.7 CCC70009.1 - 0.52 10.9 3.3 0.99 10.0 1.2 2.2 2 0 0 2 2 2 0 YtxH-like protein CENP-F_leu_zip PF10473.9 CCC70009.1 - 0.72 9.9 9.5 0.088 12.8 2.9 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 LPP20 PF02169.16 CCC70009.1 - 1.2 9.5 4.5 2.5 8.5 0.3 2.7 2 1 1 3 3 3 0 LPP20 lipoprotein Microtub_bd PF16796.5 CCC70010.1 - 1.9e-21 76.5 6.3 8.5e-21 74.4 6.3 2.2 1 1 0 1 1 1 1 Microtubule binding Golgin_A5 PF09787.9 CCC70010.1 - 0.11 11.9 25.0 0.054 12.9 21.0 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 PRT_C PF08372.10 CCC70010.1 - 0.13 12.0 0.0 0.27 11.0 0.0 1.5 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal CdvA PF18822.1 CCC70010.1 - 3.5 7.5 22.6 0.038 13.8 1.3 3.7 1 1 1 3 3 3 0 CdvA-like coiled-coil domain SlyX PF04102.12 CCC70010.1 - 4.9 7.8 11.1 1.6 9.4 0.2 4.3 2 1 1 3 3 3 0 SlyX ATG16 PF08614.11 CCC70010.1 - 9.8 6.3 22.0 4.7 7.4 4.8 2.6 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Cyclin_N PF00134.23 CCC70011.1 - 6.2e-41 139.1 0.0 1.1e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain RXT2_N PF08595.11 CCC70011.1 - 3.4 7.7 8.6 2.4 8.2 2.8 2.5 3 0 0 3 3 3 0 RXT2-like, N-terminal Rot1 PF10681.9 CCC70012.1 - 6.2e-97 323.2 0.2 7.4e-97 322.9 0.2 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal XPA_C PF05181.12 CCC70013.1 - 6.4e-22 77.3 0.1 1.3e-21 76.3 0.1 1.5 1 0 0 1 1 1 1 XPA protein C-terminus XPA_N PF01286.18 CCC70013.1 - 0.0031 17.5 0.8 0.0031 17.5 0.8 2.4 2 0 0 2 2 2 1 XPA protein N-terminal EFTUD2 PF16004.5 CCC70013.1 - 0.032 14.8 4.4 0.052 14.1 0.2 2.6 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus ERG2_Sigma1R PF04622.12 CCC70014.1 - 1.4e-93 312.1 0.8 1.6e-93 311.9 0.8 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Porin_3 PF01459.22 CCC70015.1 - 2.3e-87 292.9 0.2 2.7e-87 292.7 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic porin Inp1 PF12634.7 CCC70016.1 - 2.5e-43 147.4 0.2 2.5e-43 147.4 0.2 2.1 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 PFK PF00365.20 CCC70017.1 - 5.2e-181 600.2 2.8 2.2e-99 332.4 1.1 2.4 3 0 0 3 3 3 2 Phosphofructokinase DUF4667 PF15700.5 CCC70018.1 - 3.4e-71 240.2 28.3 4.4e-71 239.8 28.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4667) DUF4639 PF15479.6 CCC70018.1 - 0.95 8.3 6.8 0.068 12.1 2.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4639) ACC_central PF08326.12 CCC70019.1 - 1.3e-261 870.0 0.0 1.7e-261 869.6 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 CCC70019.1 - 2.7e-186 620.0 0.0 3.8e-186 619.5 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 CCC70019.1 - 1.4e-53 181.6 0.0 2.8e-53 180.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 CCC70019.1 - 2e-30 105.5 0.1 4.7e-30 104.4 0.1 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CCC70019.1 - 2e-20 72.9 0.0 6.7e-20 71.2 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 CCC70019.1 - 5.6e-19 67.8 0.1 1.5e-18 66.4 0.1 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 CCC70019.1 - 0.005 16.9 0.0 0.024 14.7 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CCC70019.1 - 0.014 15.2 0.0 0.28 11.1 0.0 2.5 2 0 0 2 2 2 0 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 CCC70019.1 - 0.02 14.4 0.0 0.05 13.1 0.0 1.7 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Peptidase_S8 PF00082.22 CCC70020.1 - 3e-28 99.0 0.0 3.6e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CCC70020.1 - 7.6e-06 26.5 0.1 2.5e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase inhibitor I9 ADH_zinc_N PF00107.26 CCC70021.1 - 1.3e-11 44.6 0.0 2.1e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCC70021.1 - 0.01 15.7 0.1 0.44 10.4 0.0 2.3 1 1 1 2 2 2 0 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CCC70021.1 - 0.069 14.2 0.1 0.13 13.3 0.1 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase WBS_methylT PF12589.8 CCC70022.1 - 3.5e-12 46.9 6.9 6.5e-12 46.1 6.9 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 CCC70022.1 - 8.1e-12 45.7 0.0 2.3e-11 44.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC70022.1 - 1.4e-11 44.9 0.0 2.5e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC70022.1 - 1.5e-06 28.8 0.0 6.2e-06 26.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC70022.1 - 9.9e-06 25.4 0.0 2.3e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCC70022.1 - 0.00022 21.1 0.0 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 CCC70022.1 - 0.00041 20.0 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.19 CCC70022.1 - 0.0016 18.3 0.0 0.0033 17.2 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 CCC70022.1 - 0.0021 17.4 0.0 0.0073 15.6 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 CCC70022.1 - 0.027 13.9 0.0 0.059 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PLRV_ORF5 PF01690.17 CCC70022.1 - 0.037 12.8 0.0 0.89 8.2 0.0 2.0 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Methyltransf_32 PF13679.6 CCC70022.1 - 0.064 13.3 0.0 0.36 10.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain AdoMet_MTase PF07757.13 CCC70022.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MBOAT PF03062.19 CCC70023.1 - 8.5e-58 196.4 37.5 1.2e-57 195.8 37.5 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ank_5 PF13857.6 CCC70024.1 - 1.8e-14 53.6 0.2 3.3e-11 43.2 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCC70024.1 - 1.3e-11 44.9 0.0 2.4e-10 40.8 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCC70024.1 - 7.8e-10 39.1 1.0 1.3e-06 28.8 0.1 2.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 CCC70024.1 - 4.2e-08 33.3 1.2 7.4e-05 23.0 0.2 2.7 2 1 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CCC70024.1 - 3.9e-06 26.8 0.1 0.00025 21.2 0.1 3.1 3 0 0 3 3 3 1 Ankyrin repeat DUF1682 PF07946.14 CCC70025.1 - 1.4e-72 244.7 8.8 1.7e-72 244.4 8.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF1374 PF07118.11 CCC70025.1 - 0.0015 19.0 1.5 0.12 12.9 0.5 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1374) HCV_NS4b PF01001.19 CCC70025.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b FerA PF08165.11 CCC70025.1 - 0.19 11.7 0.2 0.19 11.7 0.2 2.5 2 0 0 2 2 2 0 FerA (NUC095) domain SWIB PF02201.18 CCC70026.1 - 1.9e-05 24.4 0.1 0.13 12.2 0.0 2.6 2 0 0 2 2 2 2 SWIB/MDM2 domain Na_Ca_ex_C PF16494.5 CCC70026.1 - 0.086 13.3 0.2 0.37 11.3 0.0 2.1 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain Selenoprotein_S PF06936.11 CCC70026.1 - 0.11 12.3 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Selenoprotein S (SelS) APG6_N PF17675.1 CCC70026.1 - 0.19 12.2 2.9 0.37 11.3 0.4 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3439 PF11921.8 CCC70026.1 - 8.8 6.3 6.1 0.61 10.1 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Thr_synth_N PF14821.6 CCC70027.1 - 3.8e-29 100.7 0.0 1.5e-28 98.8 0.0 2.1 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.25 CCC70027.1 - 3e-12 46.6 0.0 8.5e-12 45.1 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Atx10homo_assoc PF09759.9 CCC70028.1 - 1.4e-35 121.3 2.4 1.9e-35 120.8 0.4 2.3 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain WD40 PF00400.32 CCC70029.1 - 1.7e-43 145.7 12.3 2.8e-09 37.5 0.1 12.7 14 0 0 14 14 13 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC70029.1 - 4.9e-31 106.9 0.0 0.0014 18.9 0.0 9.2 4 2 6 10 10 10 7 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 CCC70029.1 - 4.2e-25 88.1 0.0 8.2e-25 87.2 0.0 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.11 CCC70029.1 - 1.1e-09 38.4 2.8 0.00065 19.6 0.0 5.2 4 1 2 6 6 6 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCC70029.1 - 5.1e-07 29.0 4.5 0.22 10.5 0.0 6.0 4 3 2 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCC70029.1 - 5.3e-06 26.0 2.4 1.8 7.8 0.0 5.4 4 2 1 5 5 5 1 WD40-like domain Nup160 PF11715.8 CCC70029.1 - 5.1e-05 22.1 4.0 0.48 9.0 0.0 4.7 3 2 3 6 6 6 3 Nucleoporin Nup120/160 WD40_3 PF15911.5 CCC70029.1 - 0.00063 19.7 0.1 0.0072 16.3 0.0 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Nbas_N PF15492.6 CCC70029.1 - 0.01 15.2 0.3 11 5.3 0.0 4.3 3 2 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 CCC70029.1 - 0.015 14.9 1.9 0.23 11.0 0.7 3.0 2 1 0 2 2 2 0 PQQ-like domain RAB3GAP2_N PF14655.6 CCC70029.1 - 0.038 13.3 0.1 1.8 7.7 0.0 3.1 2 1 0 3 3 3 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PALB2_WD40 PF16756.5 CCC70029.1 - 0.058 12.3 0.1 8.4 5.2 0.1 2.4 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 CCC70029.1 - 0.061 11.8 0.9 6.6 5.2 0.0 3.1 3 1 1 4 4 4 0 Cytochrome D1 heme domain PD40 PF07676.12 CCC70029.1 - 0.087 12.8 0.0 1.1e+02 3.0 0.0 4.4 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.9 CCC70029.1 - 0.67 9.7 3.8 6.2 6.6 0.2 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature UPF0029 PF01205.19 CCC70030.1 - 2.9e-33 114.3 0.1 4.7e-33 113.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 CCC70030.1 - 1.1e-09 38.6 0.1 2.9e-09 37.2 0.1 1.8 1 1 0 1 1 1 1 RWD domain TPR_2 PF07719.17 CCC70031.1 - 6.9e-07 28.9 0.0 0.019 15.0 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 CCC70031.1 - 0.00011 21.8 0.0 0.04 13.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCC70031.1 - 0.00038 20.9 0.0 0.00056 20.4 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.6 CCC70031.1 - 0.0013 18.8 0.1 1.1 9.6 0.0 2.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCC70031.1 - 0.0053 16.8 0.0 0.05 13.7 0.0 2.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Ytp1 PF10355.9 CCC70032.1 - 1.4e-112 375.5 9.0 2e-112 374.9 9.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.9 CCC70032.1 - 5.7e-24 83.9 9.9 5.7e-24 83.9 9.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) G10 PF01125.17 CCC70033.1 - 1.9e-62 209.3 7.4 2.2e-62 209.2 7.4 1.0 1 0 0 1 1 1 1 G10 protein Forkhead PF00250.18 CCC70034.1 - 1.6e-33 114.8 0.4 4.3e-33 113.4 0.4 1.8 1 0 0 1 1 1 1 Forkhead domain zf-C3HC4_2 PF13923.6 CCC70035.1 - 3.3e-12 46.0 15.9 6.5e-12 45.1 11.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCC70035.1 - 4.8e-10 39.1 11.5 4.8e-10 39.1 11.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC70035.1 - 4.7e-09 36.1 15.8 1.4e-07 31.4 10.1 2.8 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_3 PF13920.6 CCC70035.1 - 5.2e-08 32.6 13.0 1.2e-07 31.5 7.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCC70035.1 - 4.8e-07 30.0 15.9 1.7e-06 28.3 10.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 CCC70035.1 - 9.8e-07 28.6 15.9 6.4e-06 26.0 9.4 2.5 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCC70035.1 - 1.1e-06 28.4 14.3 6.5e-06 25.9 8.1 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 CCC70035.1 - 1.9e-06 27.9 11.4 1.9e-06 27.9 11.4 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 CCC70035.1 - 3.8e-06 26.7 4.4 3.8e-06 26.7 4.4 1.7 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 CCC70035.1 - 1.3e-05 25.4 8.9 2e-05 24.8 4.5 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain SAP PF02037.27 CCC70035.1 - 2.2e-05 24.1 0.0 6.1e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 SAP domain U-box PF04564.15 CCC70035.1 - 0.00063 19.9 0.1 0.012 15.7 0.0 2.9 3 0 0 3 3 2 1 U-box domain zf-RING_10 PF16685.5 CCC70035.1 - 0.011 15.9 5.9 0.011 15.9 5.9 2.2 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 CCC70035.1 - 0.071 12.9 7.3 0.23 11.3 2.0 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain UBZ_FAAP20 PF15750.5 CCC70035.1 - 0.26 11.3 5.1 1.6 8.8 1.3 2.8 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Mob_synth_C PF06463.13 CCC70035.1 - 0.37 10.7 5.0 0.43 10.5 1.9 2.5 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C zf-ANAPC11 PF12861.7 CCC70035.1 - 1 9.5 6.0 0.9 9.6 1.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn-C2H2_12 PF18112.1 CCC70035.1 - 1.2 9.6 6.2 1.3 9.5 0.6 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain zf-Nse PF11789.8 CCC70035.1 - 1.6 8.6 12.7 0.45 10.4 6.3 2.8 3 0 0 3 3 2 0 Zinc-finger of the MIZ type in Nse subunit zf-WRNIP1_ubi PF18279.1 CCC70035.1 - 4.1 8.3 7.1 0.58 10.9 1.6 2.5 3 0 0 3 3 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain Rad50_zn_hook PF04423.14 CCC70035.1 - 4.2 7.3 12.1 0.59 10.0 0.1 4.0 4 0 0 4 4 4 0 Rad50 zinc hook motif ANAPC4_WD40 PF12894.7 CCC70036.1 - 2.9e-06 27.5 0.0 0.15 12.4 0.0 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCC70036.1 - 0.005 17.7 0.3 16 6.6 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat PDR_assoc PF08370.11 CCC70036.1 - 0.069 12.9 1.4 0.15 11.8 1.4 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Dimer_Tnp_hAT PF05699.14 CCC70037.1 - 6.5e-09 35.5 0.2 2.3e-08 33.7 0.2 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CCC70037.1 - 0.052 13.6 2.6 0.13 12.3 2.6 1.7 1 0 0 1 1 1 0 BED zinc finger zinc_ribbon_4 PF13717.6 CCC70037.1 - 0.16 11.9 0.9 0.35 10.8 0.9 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Lipase_3 PF01764.25 CCC70038.1 - 1.4e-08 34.7 0.0 3.2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 CCC70038.1 - 0.013 16.1 0.1 0.029 15.0 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCC70038.1 - 0.03 13.6 0.0 0.062 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCC70038.1 - 0.11 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 CCC70038.1 - 0.21 11.3 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pro_isomerase PF00160.21 CCC70039.1 - 4e-23 82.4 0.0 5.8e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Img2 PF05046.14 CCC70040.1 - 1.3e-25 89.5 0.1 1.8e-25 89.0 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) KdpC PF02669.15 CCC70040.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 K+-transporting ATPase, c chain SUI1 PF01253.22 CCC70040.1 - 0.2 12.2 0.9 0.74 10.4 0.9 1.9 1 1 0 1 1 1 0 Translation initiation factor SUI1 Pkinase PF00069.25 CCC70041.1 - 1.5e-63 214.7 0.0 2.9e-63 213.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70041.1 - 4.8e-37 127.6 0.3 1.5e-25 90.0 0.3 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCC70041.1 - 0.00011 21.6 0.1 0.00031 20.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Chordopox_A30L PF06015.12 CCC70041.1 - 0.0071 16.1 1.6 0.074 12.9 0.0 3.3 3 0 0 3 3 3 1 Chordopoxvirus A30L protein Kdo PF06293.14 CCC70041.1 - 0.056 12.8 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CCC70041.1 - 0.1 11.4 0.0 0.1 11.4 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 CCC70041.1 - 0.17 11.8 0.0 0.4 10.6 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 CCC70042.1 - 1.5e-62 206.0 32.2 8.3e-10 39.1 0.1 9.1 9 0 0 9 9 9 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC70042.1 - 8e-20 70.9 3.9 0.00023 21.4 0.0 5.4 3 2 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 CCC70042.1 - 6.5e-10 39.4 0.0 1.3e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 CCC70042.1 - 2.2e-08 34.2 0.5 0.00018 21.4 0.0 3.9 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 CCC70042.1 - 1.1e-06 27.7 4.5 1.5 7.3 0.0 5.6 4 2 2 6 6 6 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCC70042.1 - 0.00067 18.7 0.1 0.96 8.3 0.0 4.1 4 1 0 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 CCC70042.1 - 0.0012 17.7 2.1 0.28 9.9 0.2 3.5 2 1 2 4 4 4 1 Nup133 N terminal like WD40_like PF17005.5 CCC70042.1 - 0.0074 15.6 0.0 2.5 7.3 0.0 3.6 4 0 0 4 4 4 1 WD40-like domain Nbas_N PF15492.6 CCC70042.1 - 0.0079 15.6 0.7 0.92 8.8 0.2 2.7 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 CCC70042.1 - 0.02 13.5 0.1 0.21 10.1 0.1 2.6 3 1 0 3 3 3 0 Cytochrome D1 heme domain Glucosamine_iso PF01182.20 CCC70043.1 - 6.1e-52 176.7 0.0 8.4e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PQ-loop PF04193.14 CCC70044.1 - 7.9e-23 80.0 16.2 4.7e-12 45.5 0.2 3.5 2 1 1 3 3 3 2 PQ loop repeat DUF3215 PF11503.8 CCC70045.1 - 1e-17 63.7 0.3 1.3e-17 63.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) PI31_Prot_C PF08577.11 CCC70046.1 - 1.9e-13 51.4 10.3 1.9e-13 51.4 10.3 2.3 2 0 0 2 2 2 1 PI31 proteasome regulator DUF1137 PF06587.11 CCC70046.1 - 0.02 14.9 0.1 0.032 14.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1137) NCE101 PF11654.8 CCC70047.1 - 1.4e-19 69.5 0.9 1.4e-19 69.5 0.9 1.5 2 0 0 2 2 2 1 Non-classical export protein 1 Y_phosphatase2 PF03162.13 CCC70048.1 - 7.4e-36 123.2 2.2 5.9e-24 84.5 0.7 2.5 1 1 1 2 2 2 2 Tyrosine phosphatase family ALMT PF11744.8 CCC70048.1 - 8.9 5.0 8.6 4.1 6.1 0.2 2.2 2 0 0 2 2 2 0 Aluminium activated malate transporter CDC50 PF03381.15 CCC70049.1 - 2.6e-88 296.2 0.2 3.1e-88 295.9 0.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Not1 PF04054.15 CCC70050.1 - 9.9e-126 419.5 7.2 9.9e-126 419.5 7.2 2.9 2 0 0 2 2 2 1 CCR4-Not complex component, Not1 CNOT1_HEAT_N PF16419.5 CCC70050.1 - 1.5e-87 293.1 10.7 1.5e-87 293.1 10.7 2.5 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 HEAT repeat CNOT1_CAF1_bind PF16415.5 CCC70050.1 - 4.6e-87 291.1 5.1 4.6e-87 291.1 5.1 2.6 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 CCC70050.1 - 1e-41 142.2 0.1 1e-41 142.2 0.1 2.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 CCC70050.1 - 1.8e-38 131.8 2.4 1.8e-38 131.8 2.4 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 CCC70050.1 - 3e-13 50.1 2.5 3e-13 50.1 2.5 3.5 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Nab2 PF11517.8 CCC70050.1 - 0.065 13.5 0.3 0.33 11.3 0.3 2.3 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) TFIIA PF03153.13 CCC70050.1 - 3 7.7 26.1 1.6 8.6 17.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MutS_V PF00488.21 CCC70051.1 - 7.1e-62 208.8 0.0 1.9e-61 207.4 0.0 1.8 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 CCC70051.1 - 2.1e-32 112.9 1.6 2.1e-32 112.9 1.6 2.5 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 CCC70051.1 - 1.8e-28 99.0 0.3 4.5e-28 97.8 0.1 1.8 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.18 CCC70051.1 - 6.9e-07 29.5 1.6 2.3e-06 27.9 0.2 2.6 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 CCC70051.1 - 2.3e-05 24.7 1.2 0.00014 22.1 0.2 2.9 3 0 0 3 3 3 1 MutS domain II Baculo_PEP_C PF04513.12 CCC70051.1 - 0.84 9.7 9.5 3.8 7.5 0.0 4.4 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.25 CCC70052.1 - 4.3e-77 259.0 0.2 7.9e-77 258.2 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70052.1 - 7.4e-32 110.6 0.0 4.3e-21 75.4 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCC70052.1 - 5.1e-09 35.8 0.8 6.4e-06 25.7 0.1 3.1 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 CCC70052.1 - 0.0036 16.1 0.0 0.0036 16.1 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 CCC70052.1 - 0.17 11.7 0.0 2.2 8.1 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF866 PF05907.13 CCC70053.1 - 1.3e-43 148.6 3.0 1.6e-43 148.3 3.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Flocculin_t3 PF13928.6 CCC70054.1 - 2.8e-15 56.5 74.9 9.5e-07 29.2 11.3 22.7 14 5 4 18 18 18 5 Flocculin type 3 repeat Cofilin_ADF PF00241.20 CCC70055.1 - 8.7e-22 77.2 0.0 2.3e-21 75.8 0.0 1.8 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 CCC70055.1 - 7.3e-16 57.5 0.7 7.3e-16 57.5 0.7 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CCC70055.1 - 1.6e-13 50.3 0.3 5.1e-13 48.7 0.2 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 CCC70055.1 - 6.1e-06 25.8 0.0 1.4e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Anophelin PF10731.9 CCC70055.1 - 1.8 8.5 5.6 5.6 6.9 0.2 3.3 3 0 0 3 3 3 0 Thrombin inhibitor from mosquito Glyco_hydro_16 PF00722.21 CCC70056.1 - 1e-18 67.4 3.4 2.3e-18 66.3 3.4 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-LYAR PF08790.11 CCC70057.1 - 2.6e-14 52.8 7.9 5.3e-14 51.8 7.9 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.8 CCC70057.1 - 0.01 16.1 3.8 0.082 13.2 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CAF1 PF04857.20 CCC70057.1 - 0.024 13.8 9.5 0.029 13.5 9.5 1.1 1 0 0 1 1 1 0 CAF1 family ribonuclease Slu7 PF11708.8 CCC70057.1 - 0.025 14.4 13.5 0.032 14.0 13.5 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor C_Hendra PF16821.5 CCC70057.1 - 0.031 14.1 9.4 0.046 13.6 9.4 1.2 1 0 0 1 1 1 0 C protein from hendra and measles viruses XPA_N PF01286.18 CCC70057.1 - 0.06 13.4 3.2 2.1 8.5 0.1 2.3 2 0 0 2 2 2 0 XPA protein N-terminal zf_UBZ PF18439.1 CCC70057.1 - 0.1 12.2 1.8 9.4 5.9 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C2H2_4 PF13894.6 CCC70057.1 - 0.25 12.3 6.2 1.3 10.1 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger PPL5 PF18168.1 CCC70057.1 - 0.39 10.0 8.5 0.46 9.7 8.5 1.1 1 0 0 1 1 1 0 Prim-pol family 5 NHS PF15273.6 CCC70057.1 - 0.61 9.1 11.9 0.67 9.0 11.9 1.0 1 0 0 1 1 1 0 NHS-like zf-met PF12874.7 CCC70057.1 - 0.65 10.5 5.3 4 8.0 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type MAS20 PF02064.15 CCC70057.1 - 1.9 8.6 12.9 2.9 8.0 12.9 1.3 1 0 0 1 1 1 0 MAS20 protein import receptor zf-C2H2 PF00096.26 CCC70057.1 - 3.2 8.4 5.6 2 9.0 1.0 2.6 2 1 0 2 2 2 0 Zinc finger, C2H2 type Ndc1_Nup PF09531.10 CCC70057.1 - 3.8 6.1 6.3 4.3 5.9 6.3 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 CCC70057.1 - 4.5 5.9 7.6 5 5.8 7.6 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 CCC70057.1 - 7.1 5.7 8.1 8.4 5.5 8.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter zf-H2C2_2 PF13465.6 CCC70057.1 - 8.5 7.0 9.5 30 5.3 4.3 3.2 1 1 1 2 2 2 0 Zinc-finger double domain Csm1_N PF18504.1 CCC70058.1 - 6.3e-26 90.5 10.3 6.3e-26 90.5 10.3 2.0 2 0 0 2 2 2 1 Csm1 N-terminal domain Csm1 PF12539.8 CCC70058.1 - 1.1e-22 80.5 0.1 1.9e-22 79.6 0.1 1.4 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 NtA PF03146.15 CCC70058.1 - 0.038 13.9 0.2 0.064 13.1 0.2 1.3 1 0 0 1 1 1 0 Agrin NtA domain DUF5094 PF17015.5 CCC70058.1 - 0.16 12.1 5.0 2.1 8.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) WD40 PF00400.32 CCC70059.1 - 8.5e-54 178.3 15.8 4.4e-09 36.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.10 CCC70059.1 - 1.8e-27 95.4 11.9 3.4e-27 94.5 11.9 1.5 1 0 0 1 1 1 1 Tup N-terminal ANAPC4_WD40 PF12894.7 CCC70059.1 - 9.9e-18 64.2 0.1 0.0002 21.6 0.0 6.6 1 1 4 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 CCC70059.1 - 9.9e-06 25.1 3.4 0.99 8.7 0.1 4.4 3 1 0 4 4 4 2 WD40-like domain Nup160 PF11715.8 CCC70059.1 - 1.3e-05 24.0 2.5 1.5 7.4 0.1 4.3 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 CCC70059.1 - 0.00025 20.1 0.3 0.4 9.6 0.0 4.0 2 1 2 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 CCC70059.1 - 0.011 14.1 0.0 10 4.3 0.0 3.7 2 2 2 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz Peptidase_S9_N PF02897.15 CCC70059.1 - 0.019 13.8 0.8 0.86 8.3 0.1 2.5 1 1 1 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Ret2_MD PF18528.1 CCC70059.1 - 0.072 13.5 0.1 2.4 8.6 0.1 2.7 1 1 1 2 2 2 0 RNA editing 3' terminal uridylyl transferase 2 middle domain PALB2_WD40 PF16756.5 CCC70059.1 - 0.12 11.3 0.0 5.5 5.8 0.0 2.6 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Thioredoxin PF00085.20 CCC70060.1 - 1.9e-27 95.3 0.1 2.4e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 CCC70060.1 - 2.6e-07 30.4 0.0 3.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 CCC70060.1 - 3e-05 24.3 0.1 0.0014 18.9 0.1 2.3 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 CCC70060.1 - 3e-05 24.4 0.2 5.6e-05 23.5 0.2 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 CCC70060.1 - 0.00017 21.5 0.1 0.00033 20.6 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family TraF PF13728.6 CCC70060.1 - 0.0016 18.3 0.0 0.0016 18.3 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.11 CCC70060.1 - 0.0023 17.9 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 CCC70060.1 - 0.0026 17.5 0.0 0.1 12.3 0.0 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_3 PF13192.6 CCC70060.1 - 0.0043 17.1 0.1 0.0073 16.3 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin domain RE_Eco29kI PF09517.10 CCC70060.1 - 0.0048 16.5 0.0 0.0062 16.2 0.0 1.1 1 0 0 1 1 1 1 Eco29kI restriction endonuclease OST3_OST6 PF04756.13 CCC70060.1 - 0.018 14.4 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Phosducin PF02114.16 CCC70060.1 - 0.074 12.0 0.0 0.079 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin DUF953 PF06110.11 CCC70060.1 - 0.089 12.4 0.4 0.16 11.6 0.4 1.6 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) DSBA PF01323.20 CCC70060.1 - 0.15 11.8 0.3 5.5 6.7 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Lipoprotein_7 PF01540.16 CCC70061.1 - 0.082 12.2 0.1 0.093 12.0 0.1 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Med12 PF09497.10 CCC70062.1 - 2.2e-22 79.1 0.2 5.2e-22 77.9 0.2 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Kdo_hydroxy PF11004.8 CCC70062.1 - 0.039 13.2 0.2 0.12 11.6 0.2 1.8 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase NOP19 PF10863.8 CCC70062.1 - 0.073 12.9 0.4 0.19 11.6 0.4 1.7 1 0 0 1 1 1 0 Nucleolar protein 19 TFCD_C PF12612.8 CCC70062.1 - 0.15 11.9 1.4 1 9.2 0.1 3.0 2 0 0 2 2 2 0 Tubulin folding cofactor D C terminal PP2C PF00481.21 CCC70063.1 - 2.1e-30 106.2 0.0 2.6e-29 102.6 0.0 2.3 2 1 0 2 2 2 1 Protein phosphatase 2C P34-Arc PF04045.14 CCC70064.1 - 8.7e-94 313.7 1.1 1.1e-93 313.4 1.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc PAT1 PF09770.9 CCC70065.1 - 4.6e-79 266.8 72.8 1.3e-43 149.5 0.0 5.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 Epimerase PF01370.21 CCC70066.1 - 2.2e-16 60.0 0.0 2.9e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 CCC70066.1 - 1.2e-10 41.3 0.0 3.6e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 CCC70066.1 - 2.9e-09 36.3 0.0 3.8e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CCC70066.1 - 7.5e-07 28.6 0.0 5.8e-06 25.7 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 CCC70066.1 - 2.2e-06 27.2 0.0 7.3e-05 22.3 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 CCC70066.1 - 1.9e-05 24.6 0.0 3.5e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 CCC70066.1 - 2.8e-05 24.1 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCC70066.1 - 0.0047 16.1 0.1 0.12 11.5 0.1 2.4 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein NmrA PF05368.13 CCC70066.1 - 0.012 15.2 0.0 0.044 13.3 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family adh_short_C2 PF13561.6 CCC70066.1 - 0.15 11.5 0.0 0.43 10.1 0.0 1.8 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Zn_clus PF00172.18 CCC70067.1 - 2.8e-08 33.7 9.5 6.5e-08 32.6 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.16 CCC70068.1 - 3e-18 65.9 22.5 3e-18 65.9 22.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CPP1-like PF11833.8 CCC70068.1 - 2.5 7.7 6.1 2.4 7.8 0.2 2.8 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Ureidogly_lyase PF04115.12 CCC70069.1 - 1.6e-50 171.5 0.0 2e-50 171.2 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate lyase Malate_synthase PF01274.22 CCC70070.1 - 2.7e-218 725.5 0.0 3.4e-218 725.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DUF1870 PF08965.10 CCC70070.1 - 0.0041 17.1 0.1 1.2 9.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1870) Asp_Glu_race PF01177.22 CCC70071.1 - 8e-05 22.6 0.0 0.00018 21.5 0.0 1.7 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase Amidohydro_1 PF01979.20 CCC70072.1 - 1.1e-42 146.7 0.0 1.7e-42 146.0 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 CCC70072.1 - 1.1e-11 45.0 0.0 8.1e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family DUF2357 PF09823.9 CCC70072.1 - 0.17 11.1 0.1 0.28 10.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2357) Transp_cyt_pur PF02133.15 CCC70073.1 - 6.9e-178 591.9 38.4 8e-178 591.7 38.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Allantoicase PF03561.15 CCC70074.1 - 1.5e-87 290.9 0.3 3.8e-44 150.2 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.25 CCC70074.1 - 0.0009 19.4 1.8 0.0025 17.9 0.3 2.2 2 0 0 2 2 2 1 F5/8 type C domain S-methyl_trans PF02574.16 CCC70075.1 - 3.2e-62 210.8 0.0 3.7e-62 210.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DUF4874 PF16173.5 CCC70075.1 - 0.016 14.9 0.0 0.061 13.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4874) DUF2675 PF11247.8 CCC70075.1 - 0.18 11.9 0.0 0.39 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) Flo11 PF10182.9 CCC70076.1 - 9.2e-55 184.9 1.5 1.1e-54 184.6 1.5 1.1 1 0 0 1 1 1 1 Flo11 domain FMN_dh PF01070.18 CCC70077.1 - 2.3e-115 385.4 0.0 2.6e-115 385.2 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.17 CCC70077.1 - 1.7e-07 30.7 0.0 2.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.15 CCC70077.1 - 0.0062 16.0 0.0 0.0077 15.7 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 CCC70077.1 - 0.013 14.5 0.1 0.033 13.2 0.1 1.7 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 CCC70077.1 - 0.077 12.4 0.1 2.6 7.4 0.0 2.6 3 0 0 3 3 3 0 Histidine biosynthesis protein ThiG PF05690.14 CCC70077.1 - 0.08 12.2 0.0 13 5.0 0.0 2.7 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG MFS_1 PF07690.16 CCC70078.1 - 4.5e-22 78.5 12.2 7.8e-22 77.7 11.0 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_3 PF16083.5 CCC70078.1 - 0.023 14.8 0.3 0.12 12.6 0.3 2.2 1 0 0 1 1 1 0 LydA holin phage, holin superfamily III Sir1 PF11603.8 CCC70079.1 - 8.3e-37 126.3 0.2 2.8e-36 124.7 0.1 1.9 2 0 0 2 2 2 1 Regulatory protein Sir1 DUF4897 PF16238.5 CCC70080.1 - 0.068 13.0 0.4 0.12 12.2 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4897) Sir1 PF11603.8 CCC70082.1 - 8.4e-37 126.3 0.1 7e-36 123.3 0.1 2.3 2 0 0 2 2 2 1 Regulatory protein Sir1 Transmemb_17 PF09799.9 CCC70083.1 - 0.22 12.1 2.9 0.34 11.5 2.9 1.4 1 0 0 1 1 1 0 Predicted membrane protein Pex2_Pex12 PF04757.14 CCC70084.1 - 2.1e-13 50.4 8.3 4.6e-13 49.3 8.3 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 CCC70084.1 - 0.0008 19.2 15.9 0.0014 18.5 15.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sugar_tr PF00083.24 CCC70086.1 - 8.6e-163 542.4 31.6 9.9e-163 542.2 31.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC70086.1 - 1.1e-31 110.1 22.2 1.1e-31 110.1 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCC70086.1 - 0.00017 20.2 2.0 0.00029 19.4 1.1 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-C2H2 PF00096.26 CCC70087.1 - 6e-09 35.9 28.6 0.0021 18.4 0.7 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC70087.1 - 2.3e-06 28.0 28.1 0.0023 18.6 0.3 5.2 5 0 0 5 5 5 3 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCC70087.1 - 4.1e-05 23.8 7.6 0.0018 18.6 2.1 5.1 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCC70087.1 - 9.8e-05 22.5 0.6 9.8e-05 22.5 0.6 3.1 4 0 0 4 4 4 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCC70087.1 - 0.027 14.9 10.3 0.16 12.4 0.4 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type RNA_pol_Rpb2_2 PF04561.14 CCC70087.1 - 0.061 13.0 0.1 0.53 9.9 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 2 zf-C2HE PF16278.5 CCC70087.1 - 0.31 11.5 9.6 0.13 12.7 5.4 2.6 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger FOXP-CC PF16159.5 CCC70087.1 - 0.59 10.8 5.1 31 5.3 0.0 3.9 4 0 0 4 4 4 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 CCC70087.1 - 3 8.2 10.0 0.53 10.6 1.0 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) Hexokinase_2 PF03727.16 CCC70088.1 - 1.3e-78 263.8 0.0 2.2e-78 263.0 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCC70088.1 - 7.5e-73 244.7 0.0 1e-72 244.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 CCC70088.1 - 0.053 13.1 0.0 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain IGR PF09597.10 CCC70088.1 - 0.061 13.4 0.2 13 6.0 0.0 2.9 3 0 0 3 3 3 0 IGR protein motif Ppx-GppA PF02541.16 CCC70089.1 - 1.1e-64 218.7 0.0 1.4e-64 218.3 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Suppressor_P21 PF11479.8 CCC70089.1 - 0.12 12.5 0.6 0.25 11.5 0.6 1.5 1 0 0 1 1 1 0 RNA silencing suppressor P21 C-terminal domain Sec63 PF02889.16 CCC70090.1 - 1.9e-26 92.8 0.4 3.3e-26 92.0 0.4 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.29 CCC70090.1 - 7.8e-25 87.6 0.0 2.1e-24 86.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 CCC70090.1 - 1.1e-13 51.6 0.1 2.7e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCC70090.1 - 1.8e-11 44.3 0.2 2e-10 41.0 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 CCC70090.1 - 0.0011 19.3 0.1 0.021 15.1 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CCC70090.1 - 0.05 13.9 0.0 0.32 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain UvrD-helicase PF00580.21 CCC70090.1 - 0.11 12.0 2.0 0.33 10.4 0.0 2.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain T2SSE PF00437.20 CCC70090.1 - 0.11 11.5 0.0 0.28 10.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2420 PF10336.9 CCC70091.1 - 1.5e-37 127.9 1.3 2.6e-37 127.1 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) PDEase_II PF02112.15 CCC70093.1 - 2.9e-61 207.5 0.6 5.2e-61 206.6 0.6 1.3 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II DUF1765 PF08578.10 CCC70093.1 - 0.15 12.6 0.1 0.34 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1765) RAI1 PF08652.11 CCC70094.1 - 9.5e-26 89.8 0.2 2e-25 88.8 0.2 1.6 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease tRNA-synt_1c PF00749.21 CCC70095.1 - 2.2e-121 404.6 0.1 2.9e-121 404.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 CCC70095.1 - 1.1e-37 129.6 0.8 1.4e-36 126.0 0.2 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GluRS_N PF18466.1 CCC70095.1 - 6.8e-12 45.6 2.1 2e-11 44.1 2.1 1.9 1 0 0 1 1 1 1 Glutamate--tRNA ligase N-terminal domain GST_C PF00043.25 CCC70095.1 - 0.016 15.4 0.0 0.072 13.3 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCC70095.1 - 0.016 15.2 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 CCC70095.1 - 0.21 10.9 3.0 0.11 11.8 0.3 1.9 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Plus-3 PF03126.18 CCC70096.1 - 8.7e-28 97.0 0.5 2.8e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 Plus-3 domain A_deamin PF02137.18 CCC70097.1 - 5.6e-31 108.2 0.1 9.6e-31 107.4 0.0 1.4 2 0 0 2 2 2 1 Adenosine-deaminase (editase) domain ANAPC10 PF03256.16 CCC70098.1 - 1.1e-39 136.1 0.0 1.4e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 CCC70098.1 - 1.3e-05 25.3 0.0 2.3e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 CCC70098.1 - 0.071 13.3 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 PITH domain Cse1 PF08506.10 CCC70099.1 - 1.5e-171 570.3 7.9 2.4e-171 569.6 7.9 1.3 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.15 CCC70099.1 - 3.9e-108 361.8 3.6 3.9e-108 361.8 3.6 2.4 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 CCC70099.1 - 3e-17 62.3 0.4 8.4e-16 57.7 0.0 3.4 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CCC70099.1 - 0.0052 16.8 2.8 0.048 13.7 0.1 3.9 3 2 0 3 3 3 1 Exportin 1-like protein HEAT_EZ PF13513.6 CCC70099.1 - 0.022 15.3 0.1 21 5.7 0.0 4.2 3 0 0 3 3 3 0 HEAT-like repeat CBFB_NFYA PF02045.15 CCC70100.1 - 4.5e-26 91.2 8.7 4.5e-26 91.2 8.7 1.9 2 0 0 2 2 2 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B GIDA PF01134.22 CCC70101.1 - 5.4e-156 519.6 0.0 7.1e-156 519.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 CCC70101.1 - 2.7e-72 243.3 0.6 3.9e-72 242.8 0.6 1.2 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 CCC70101.1 - 2.4e-05 23.7 3.0 0.0004 19.7 0.5 2.8 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCC70101.1 - 8.2e-05 22.1 0.2 0.00014 21.4 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 CCC70101.1 - 0.00028 20.1 1.0 0.0019 17.4 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 CCC70101.1 - 0.013 14.9 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 CCC70101.1 - 0.02 14.5 1.2 2.3 7.7 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 CCC70101.1 - 0.035 14.6 0.1 0.11 13.0 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCC70101.1 - 0.062 12.5 0.1 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCC70101.1 - 0.13 11.0 0.9 1.2 7.7 0.4 2.2 2 0 0 2 2 2 0 HI0933-like protein GARS_A PF01071.19 CCC70102.1 - 5.7e-82 274.2 0.1 1e-81 273.4 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 CCC70102.1 - 1.1e-33 115.8 0.0 5.8e-33 113.5 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.22 CCC70102.1 - 2.7e-32 112.1 0.0 6.2e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.16 CCC70102.1 - 2.4e-28 98.2 0.2 6.1e-28 96.9 0.2 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 CCC70102.1 - 4.8e-16 59.2 1.5 4.8e-16 59.2 1.5 2.3 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_3 PF02655.14 CCC70102.1 - 6.6e-07 29.5 0.1 1.8e-06 28.1 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.22 CCC70102.1 - 4.6e-06 26.3 0.0 8.7e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 CCC70102.1 - 0.0019 17.7 0.0 0.0038 16.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATPgrasp_ST PF14397.6 CCC70102.1 - 0.057 12.7 0.0 0.62 9.3 0.0 2.3 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp Sec15 PF04091.12 CCC70103.1 - 4.6e-103 344.9 6.1 4.6e-103 344.9 6.1 2.1 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like THUMP PF02926.17 CCC70104.1 - 1e-26 93.7 2.1 1e-26 93.7 0.9 1.6 2 0 0 2 2 2 1 THUMP domain DUF1077 PF06417.12 CCC70105.1 - 3.3e-39 133.5 5.7 4.4e-39 133.1 5.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Herpes_UL17 PF04559.12 CCC70106.1 - 0.07 11.9 0.0 0.084 11.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein Insulin_TMD PF17870.1 CCC70106.1 - 0.34 11.0 2.6 0.66 10.1 2.4 1.6 1 1 0 1 1 1 0 Insulin receptor trans-membrane segment SAPS PF04499.15 CCC70107.1 - 2.8e-155 517.8 17.0 2.8e-155 517.8 17.0 1.9 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein DUF5600 PF18150.1 CCC70108.1 - 0.92 10.1 5.8 11 6.7 0.1 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF5600) DUF3800 PF12686.7 CCC70108.1 - 7.2 7.3 6.9 3.4e+02 1.9 6.9 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) SPRY PF00622.28 CCC70109.1 - 2.9e-27 95.1 0.0 2e-26 92.5 0.0 2.2 1 1 0 1 1 1 1 SPRY domain CLTH PF10607.9 CCC70109.1 - 3.2e-12 46.6 2.2 6.8e-12 45.5 2.2 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 CCC70109.1 - 0.016 15.2 0.1 0.045 13.7 0.1 1.8 1 0 0 1 1 1 0 LisH Ost5 PF05251.12 CCC70110.1 - 6.7e-15 55.1 8.4 7.7e-15 54.9 8.4 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 CD20 PF04103.15 CCC70110.1 - 0.0002 21.5 2.7 0.00023 21.3 2.7 1.1 1 0 0 1 1 1 1 CD20-like family DUF716 PF04819.12 CCC70110.1 - 0.016 14.9 0.1 0.018 14.7 0.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF716) COX4 PF02936.14 CCC70111.1 - 3.7e-08 33.5 0.1 4.5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV EamA PF00892.20 CCC70112.1 - 1.9e-07 31.4 31.7 7.4e-05 22.9 9.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.19 CCC70112.1 - 2 9.1 12.3 2.7 8.7 5.9 2.6 2 0 0 2 2 2 0 Small Multidrug Resistance protein Hydrolase PF00702.26 CCC70113.1 - 0.00061 20.1 0.0 0.035 14.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Lambda_Bor PF06291.11 CCC70114.1 - 0.079 13.0 0.1 0.25 11.4 0.1 1.9 1 0 0 1 1 1 0 Bor protein Vps51 PF08700.11 CCC70114.1 - 2.6 8.2 13.2 0.073 13.2 2.1 3.5 4 0 0 4 4 4 0 Vps51/Vps67 Flavodoxin_2 PF02525.17 CCC70115.1 - 2.9e-54 183.8 0.0 3.5e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCC70115.1 - 7.8e-12 45.2 0.0 1.8e-11 44.0 0.0 1.6 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 CCC70116.1 - 4.2e-55 186.5 0.1 4.9e-55 186.3 0.1 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCC70116.1 - 4.1e-12 46.1 0.0 9.5e-12 44.9 0.0 1.6 1 1 0 1 1 1 1 NADPH-dependent FMN reductase PC-Esterase PF13839.6 CCC70116.1 - 0.02 14.7 0.6 0.03 14.1 0.2 1.4 2 0 0 2 2 2 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Flavodoxin_4 PF12682.7 CCC70116.1 - 0.042 13.6 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin zf-HIT PF04438.16 CCC70117.1 - 0.0011 18.8 11.5 0.0011 18.8 11.5 1.8 2 0 0 2 2 2 1 HIT zinc finger Dor1 PF04124.12 CCC70117.1 - 0.025 13.3 0.6 0.034 12.8 0.6 1.2 1 0 0 1 1 1 0 Dor1-like family Fmp27_GFWDK PF10347.9 CCC70117.1 - 0.04 14.0 0.2 0.072 13.2 0.2 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ABC_tran PF00005.27 CCC70118.1 - 6.6e-50 169.2 0.0 6.5e-25 88.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 CCC70118.1 - 1.1e-21 78.0 0.2 3.2e-07 30.5 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 CCC70118.1 - 3.3e-21 75.1 3.7 3.3e-21 75.1 3.7 3.3 3 0 0 3 3 2 1 ABC transporter SMC_N PF02463.19 CCC70118.1 - 3.9e-10 39.6 0.3 0.44 9.9 0.0 4.5 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCC70118.1 - 5.6e-08 32.4 0.0 0.0039 16.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 CCC70118.1 - 1.2e-07 32.4 6.5 0.011 16.3 0.0 4.0 4 0 0 4 4 3 2 AAA domain AAA_15 PF13175.6 CCC70118.1 - 1.4e-07 31.6 0.3 0.051 13.3 0.0 3.9 4 0 0 4 4 4 2 AAA ATPase domain RsgA_GTPase PF03193.16 CCC70118.1 - 4.1e-07 30.1 0.4 0.00089 19.2 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_22 PF13401.6 CCC70118.1 - 6.5e-07 29.7 0.0 0.065 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 CCC70118.1 - 2.7e-06 27.5 0.1 0.0094 16.0 0.0 3.1 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_18 PF13238.6 CCC70118.1 - 7.4e-06 26.5 0.0 0.026 15.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.6 CCC70118.1 - 2.5e-05 24.6 0.0 0.093 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 CCC70118.1 - 2.7e-05 24.5 0.0 0.29 11.5 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.6 CCC70118.1 - 3.8e-05 24.2 0.0 0.052 13.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CCC70118.1 - 5.4e-05 23.6 0.1 0.21 12.0 0.0 3.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 CCC70118.1 - 5.4e-05 23.2 0.8 0.32 10.9 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_33 PF13671.6 CCC70118.1 - 9.8e-05 22.5 1.8 0.097 12.8 0.0 3.2 4 0 0 4 4 2 2 AAA domain Rad17 PF03215.15 CCC70118.1 - 0.00013 21.9 0.0 0.4 10.6 0.0 2.8 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_24 PF13479.6 CCC70118.1 - 0.00022 21.0 0.1 0.27 10.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.6 CCC70118.1 - 0.00042 20.3 0.0 1.1 9.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain MCM PF00493.23 CCC70118.1 - 0.0024 17.0 0.0 2.2 7.3 0.0 2.4 2 0 0 2 2 2 2 MCM P-loop domain Roc PF08477.13 CCC70118.1 - 0.0027 17.9 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_27 PF13514.6 CCC70118.1 - 0.0032 17.1 0.8 2.4 7.7 0.0 3.4 4 0 0 4 4 3 1 AAA domain Dynamin_N PF00350.23 CCC70118.1 - 0.0033 17.5 1.9 8.4 6.4 1.1 3.8 2 1 0 2 2 2 0 Dynamin family AAA_25 PF13481.6 CCC70118.1 - 0.0048 16.5 0.1 1.1 8.7 0.0 3.6 3 1 0 3 3 2 1 AAA domain AAA_5 PF07728.14 CCC70118.1 - 0.0056 16.7 0.0 3.3 7.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 CCC70118.1 - 0.0067 15.6 0.0 0.71 9.0 0.0 3.1 3 0 0 3 3 3 1 NB-ARC domain G-alpha PF00503.20 CCC70118.1 - 0.011 14.9 0.3 1.2 8.2 0.1 2.8 2 2 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 CCC70118.1 - 0.012 15.1 0.1 1.1 8.7 0.0 2.7 3 0 0 3 3 2 0 P-loop containing dynein motor region VirE PF05272.11 CCC70118.1 - 0.013 15.3 0.0 1.6 8.4 0.0 2.8 3 0 0 3 3 3 0 Virulence-associated protein E TsaE PF02367.17 CCC70118.1 - 0.016 15.2 0.2 3 7.9 0.0 2.7 2 1 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MeaB PF03308.16 CCC70118.1 - 0.017 14.1 0.2 3.1 6.7 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF87 PF01935.17 CCC70118.1 - 0.018 15.1 1.0 15 5.6 0.0 3.4 3 1 1 4 4 4 0 Helicase HerA, central domain DUF815 PF05673.13 CCC70118.1 - 0.018 14.2 0.0 6.4 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CCC70118.1 - 0.042 13.6 0.0 1 9.0 0.0 2.7 3 0 0 3 3 3 0 IstB-like ATP binding protein PduV-EutP PF10662.9 CCC70118.1 - 0.046 13.5 0.1 18 5.0 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF2813 PF11398.8 CCC70118.1 - 0.05 12.9 0.3 3.5 6.8 0.0 2.9 4 0 0 4 4 3 0 Protein of unknown function (DUF2813) AAA_30 PF13604.6 CCC70118.1 - 0.055 13.2 0.2 3.3 7.4 0.1 3.1 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 CCC70118.1 - 0.078 12.9 0.2 1.7 8.5 0.1 2.5 2 0 0 2 2 2 0 NTPase dNK PF01712.19 CCC70118.1 - 0.084 12.7 0.8 9.1 6.1 0.0 2.8 3 1 0 3 3 2 0 Deoxynucleoside kinase FeoB_N PF02421.18 CCC70118.1 - 0.087 12.3 0.0 2.9 7.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CCC70118.1 - 0.12 12.1 0.1 30 4.3 0.0 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein T2SSE PF00437.20 CCC70118.1 - 0.13 11.3 0.0 1 8.4 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein SRR1 PF07985.12 CCC70119.1 - 5.9e-18 64.7 0.0 1.4e-17 63.5 0.0 1.7 1 0 0 1 1 1 1 SRR1 NIF3 PF01784.18 CCC70121.1 - 9.2e-68 228.5 0.0 1.2e-67 228.2 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF1442 PF07279.11 CCC70121.1 - 0.061 12.6 0.1 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) DHHA1 PF02272.19 CCC70121.1 - 0.073 13.5 0.0 0.28 11.6 0.0 1.9 1 1 1 2 2 2 0 DHHA1 domain PX PF00787.24 CCC70122.1 - 9.3e-10 38.5 1.9 1.3e-09 38.0 0.3 2.1 2 0 0 2 2 2 1 PX domain PCRF PF03462.18 CCC70122.1 - 0.039 13.8 0.5 0.039 13.8 0.5 2.3 2 0 0 2 2 2 0 PCRF domain UPF0449 PF15136.6 CCC70122.1 - 0.13 12.7 9.8 2.5 8.6 0.1 2.9 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 SKA2 PF16740.5 CCC70122.1 - 6.2 6.6 11.9 0.79 9.5 2.4 3.3 3 1 0 3 3 3 0 Spindle and kinetochore-associated protein 2 SlyX PF04102.12 CCC70122.1 - 6.8 7.4 10.4 3 8.5 5.3 2.8 1 1 1 2 2 2 0 SlyX WD40 PF00400.32 CCC70123.1 - 2.1e-09 37.8 13.7 4.2e-05 24.2 0.3 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC70123.1 - 2.4e-08 34.2 0.0 0.0076 16.5 0.0 3.0 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CCC70123.1 - 0.0031 17.5 0.1 0.24 11.5 0.0 3.1 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 CCC70123.1 - 0.031 13.2 0.1 29 3.5 0.0 3.4 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cyclin_N PF00134.23 CCC70124.1 - 0.0071 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCC70124.1 - 0.036 14.4 0.1 0.067 13.6 0.1 1.5 1 0 0 1 1 1 0 Cyclin Kinesin PF00225.23 CCC70125.1 - 3e-114 381.4 0.9 4.9e-114 380.7 0.9 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 CCC70125.1 - 2.4e-26 92.4 0.0 8.9e-26 90.6 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding IMD PF08397.11 CCC70125.1 - 0.02 14.3 4.6 0.054 12.9 4.6 1.7 1 0 0 1 1 1 0 IRSp53/MIM homology domain DUF508 PF04370.12 CCC70126.1 - 4.5 7.0 13.7 0.04 13.7 3.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF508) BolA PF01722.18 CCC70127.1 - 5.6e-17 61.8 0.0 6.5e-17 61.6 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein FAD_binding_3 PF01494.19 CCC70128.1 - 3.5e-20 72.6 0.1 1e-08 34.8 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 CCC70128.1 - 0.00019 20.8 0.0 0.0012 18.1 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCC70128.1 - 0.002 17.4 0.0 0.0047 16.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 CCC70128.1 - 0.0023 17.1 0.0 0.022 13.8 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.10 CCC70128.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase DAO PF01266.24 CCC70128.1 - 0.017 14.7 0.0 0.089 12.3 0.0 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CCC70128.1 - 0.019 14.2 0.0 0.051 12.8 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CCC70128.1 - 0.02 15.1 0.0 0.05 13.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 CCC70128.1 - 0.026 13.4 0.0 0.28 10.0 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox PF00070.27 CCC70128.1 - 0.034 14.7 0.1 7.5 7.2 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HTH_53 PF18606.1 CCC70128.1 - 0.04 13.6 0.0 0.15 11.8 0.0 1.9 2 0 0 2 2 2 0 Zap helix turn helix N-terminal domain FAD_binding_2 PF00890.24 CCC70128.1 - 0.089 11.9 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 CCC70128.1 - 0.13 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding ATP_bind_3 PF01171.20 CCC70129.1 - 5.8e-19 68.5 0.0 1.2e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 PP-loop family zn-ribbon_14 PF16503.5 CCC70129.1 - 6e-15 54.5 5.0 6e-15 54.5 5.0 3.2 4 0 0 4 4 4 1 Zinc-ribbon tRNA_Me_trans PF03054.16 CCC70129.1 - 0.0043 15.9 0.0 0.0081 15.0 0.0 1.4 1 1 0 1 1 1 1 tRNA methyl transferase CTU2 PF10288.9 CCC70129.1 - 0.014 15.7 0.1 0.014 15.7 0.1 2.8 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 PAPS_reduct PF01507.19 CCC70129.1 - 0.099 12.7 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family Ras PF00071.22 CCC70130.1 - 2.6e-60 202.7 0.2 3.1e-60 202.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC70130.1 - 2.8e-34 117.9 0.1 4.1e-34 117.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC70130.1 - 3.7e-13 49.3 0.0 4.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCC70130.1 - 6e-07 29.5 0.1 9.8e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 CCC70130.1 - 0.0003 20.4 0.1 0.0015 18.1 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCC70130.1 - 0.0018 18.2 0.1 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 CCC70130.1 - 0.002 17.5 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 CCC70130.1 - 0.006 16.3 0.0 0.01 15.6 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.14 CCC70130.1 - 0.0071 15.6 0.0 0.012 14.8 0.0 1.3 1 1 0 1 1 1 1 KAP family P-loop domain AAA_22 PF13401.6 CCC70130.1 - 0.0078 16.5 0.1 0.06 13.6 0.0 2.2 1 1 1 2 2 2 1 AAA domain SRPRB PF09439.10 CCC70130.1 - 0.016 14.7 0.1 0.034 13.6 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 CCC70130.1 - 0.028 13.9 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 CCC70130.1 - 0.029 14.1 0.2 0.058 13.1 0.1 1.6 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CCC70130.1 - 0.031 14.7 0.1 0.061 13.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 CCC70130.1 - 0.034 14.7 0.4 0.047 14.2 0.4 1.5 1 1 0 1 1 1 0 ABC transporter Septin PF00735.18 CCC70130.1 - 0.04 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_7 PF12775.7 CCC70130.1 - 0.055 13.0 0.0 0.084 12.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region DUF1128 PF06569.11 CCC70130.1 - 0.12 12.4 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) AAA_21 PF13304.6 CCC70130.1 - 0.16 11.7 0.8 0.19 11.5 0.7 1.3 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system zf-C2H2 PF00096.26 CCC70131.1 - 8.1e-07 29.2 16.7 0.00016 21.9 2.6 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC70131.1 - 8.3e-07 29.2 18.9 0.0002 21.7 6.9 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC70131.1 - 0.00023 21.7 13.9 0.016 16.0 1.9 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCC70131.1 - 0.00029 21.0 1.9 0.091 13.1 0.4 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 CCC70131.1 - 0.0031 18.1 0.0 0.0092 16.6 0.0 1.8 1 0 0 1 1 1 1 FOXP coiled-coil domain TFIIA PF03153.13 CCC70131.1 - 0.066 13.2 11.1 0.088 12.8 11.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-H2C2_5 PF13909.6 CCC70131.1 - 0.072 12.9 9.2 0.49 10.2 0.6 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain EKR PF10371.9 CCC70131.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function zf-C2HE PF16278.5 CCC70131.1 - 0.85 10.1 3.7 25 5.4 0.6 2.6 2 0 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger AMPK1_CBM PF16561.5 CCC70132.1 - 1e-29 102.6 0.0 1.9e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CCC70132.1 - 4.1e-28 97.5 3.5 4.1e-28 97.5 3.5 2.5 3 0 0 3 3 3 1 5'-AMP-activated protein kinase beta subunit, interaction domain ACOX PF01756.19 CCC70133.1 - 5.4e-40 136.9 0.0 1e-39 135.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 CCC70133.1 - 7.8e-22 77.3 0.0 1.8e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 CCC70133.1 - 1.6e-10 41.6 0.1 3.8e-10 40.4 0.1 1.6 1 1 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 CCC70133.1 - 0.0012 19.0 0.0 0.0033 17.6 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain CDP-OH_P_transf PF01066.21 CCC70134.1 - 4.1e-11 43.5 1.9 4.9e-11 43.2 0.5 1.9 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Nefa_Nip30_N PF10187.9 CCC70135.1 - 4.4e-11 43.1 13.7 4.4e-11 43.1 13.7 1.7 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Nop25 PF09805.9 CCC70135.1 - 0.021 15.3 12.0 0.038 14.5 12.0 1.5 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Peptidase_S10 PF00450.22 CCC70136.1 - 9.4e-105 351.4 1.6 1.3e-104 350.9 1.6 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase BUD22 PF09073.10 CCC70136.1 - 6.8e-05 22.4 26.5 0.00012 21.6 26.5 1.2 1 0 0 1 1 1 1 BUD22 DNA_pol_phi PF04931.13 CCC70136.1 - 0.00059 18.1 36.4 0.00098 17.4 36.4 1.4 1 0 0 1 1 1 1 DNA polymerase phi Paf1 PF03985.13 CCC70136.1 - 0.0034 16.5 16.3 0.0055 15.8 16.3 1.3 1 0 0 1 1 1 1 Paf1 Zip PF02535.22 CCC70136.1 - 0.019 14.2 1.4 0.033 13.4 1.4 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 CCC70136.1 - 0.085 11.8 5.7 0.047 12.7 2.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 CCC70136.1 - 0.1 11.3 4.5 0.16 10.7 4.5 1.3 1 0 0 1 1 1 0 Presenilin CNDH2_C PF16858.5 CCC70136.1 - 0.44 10.4 12.9 1.2 9.0 12.9 1.6 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term NPR3 PF03666.13 CCC70136.1 - 0.63 8.8 12.3 1.2 7.9 12.3 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Vfa1 PF08432.10 CCC70136.1 - 4.4 7.6 15.7 14 6.0 15.7 1.8 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 CCC70136.1 - 9.1 4.4 42.2 18 3.4 42.2 1.4 1 0 0 1 1 1 0 Nop14-like family Aminotran_1_2 PF00155.21 CCC70137.1 - 5.4e-21 75.2 0.0 7.2e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 CCC70137.1 - 0.04 13.2 0.2 0.22 10.8 0.2 1.9 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family MCM PF00493.23 CCC70138.1 - 5.8e-104 346.1 0.3 8.9e-104 345.5 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCC70138.1 - 2.8e-40 137.1 0.2 1.1e-39 135.1 0.1 2.0 2 0 0 2 2 2 1 MCM OB domain MCM6_C PF18263.1 CCC70138.1 - 6.7e-33 113.2 4.5 6.7e-33 113.2 4.5 2.1 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain MCM_lid PF17855.1 CCC70138.1 - 1.1e-26 93.1 2.6 2.6e-26 91.9 2.6 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 CCC70138.1 - 6.8e-24 84.5 1.0 6.8e-24 84.5 1.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 CCC70138.1 - 3.7e-07 29.7 0.0 1.6e-06 27.7 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RRN3 PF05327.11 CCC70138.1 - 0.003 16.2 5.4 0.0059 15.2 5.4 1.4 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 Sigma54_activat PF00158.26 CCC70138.1 - 0.0062 16.3 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 CCC70138.1 - 0.0092 16.0 0.0 0.027 14.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 CCC70138.1 - 0.013 15.4 0.0 0.032 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RVT_2 PF07727.14 CCC70139.1 - 2e-20 73.5 0.0 2.8e-20 73.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SKN1 PF03935.15 CCC70140.1 - 1.4e-253 841.8 3.5 1.9e-253 841.4 3.5 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GP79 PF17463.2 CCC70141.1 - 0.046 13.7 1.1 0.098 12.7 1.1 1.5 1 0 0 1 1 1 0 Gene product 79 Asp-B-Hydro_N PF05279.11 CCC70141.1 - 1.2 9.1 28.5 2.2 8.3 28.5 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Vps62 PF06101.11 CCC70142.1 - 0.00049 18.5 2.6 0.00063 18.2 1.1 1.8 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 NDC10_II PF16787.5 CCC70143.1 - 1.4e-84 283.8 9.4 1.4e-84 283.8 9.4 2.7 3 0 0 3 3 3 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 GCR1_C PF12550.8 CCC70143.1 - 2.1e-17 63.2 1.2 7e-17 61.5 0.7 2.3 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes UPF0147 PF03685.13 CCC70143.1 - 0.11 12.6 1.0 0.28 11.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) DUF2406 PF10295.9 CCC70144.1 - 2.5e-26 92.1 0.2 6.1e-26 90.9 0.2 1.7 1 0 0 1 1 1 1 Uncharacterised protein (DUF2406) MFS_1 PF07690.16 CCC70145.1 - 4.9e-32 111.2 29.8 4.9e-32 111.2 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC70145.1 - 5.5e-14 51.9 15.1 1.3e-13 50.6 14.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Sugar_transport PF06800.12 CCC70145.1 - 0.0055 16.1 0.2 0.047 13.0 0.0 2.4 1 1 0 2 2 2 1 Sugar transport protein Proteasome PF00227.26 CCC70146.1 - 2.9e-58 196.5 0.7 3.8e-58 196.1 0.7 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCC70146.1 - 5.2e-12 45.2 0.9 8.4e-12 44.5 0.2 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature CNOT11 PF10155.9 CCC70147.1 - 0.022 14.9 1.4 0.089 12.9 0.1 2.4 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 UQ_con PF00179.26 CCC70148.1 - 3.5e-37 127.2 2.7 7e-37 126.2 2.7 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 CCC70148.1 - 1.4e-05 24.8 0.5 6.1e-05 22.7 0.5 1.8 1 1 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 CCC70148.1 - 4.7e-05 23.7 0.4 7.2e-05 23.1 0.4 1.4 1 0 0 1 1 1 1 RWD domain Band_7 PF01145.25 CCC70149.1 - 9.3e-26 90.9 3.1 1.8e-25 90.0 3.1 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 CCC70149.1 - 0.0065 15.6 1.4 0.0087 15.2 1.4 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial Band_7_1 PF13421.6 CCC70149.1 - 0.031 14.0 0.1 0.054 13.2 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family MARVEL PF01284.23 CCC70150.1 - 1.7e-23 83.2 12.3 2.3e-23 82.8 12.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain Prok-TraM PF09228.10 CCC70151.1 - 0.03 14.7 1.4 0.03 14.7 1.4 3.3 2 1 1 3 3 3 0 Prokaryotic Transcriptional repressor TraM Uteroglobin PF01099.17 CCC70151.1 - 1.8 9.0 20.0 2.1 8.7 1.0 3.8 3 0 0 3 3 3 0 Uteroglobin family SYF2 PF08231.12 CCC70152.1 - 9.9e-11 42.3 20.9 9.9e-11 42.3 20.9 1.8 1 1 1 2 2 2 1 SYF2 splicing factor Peptidase_C10 PF01640.17 CCC70152.1 - 0.62 10.3 8.5 0.38 11.1 5.0 1.9 1 1 1 2 2 2 0 Peptidase C10 family Utp8 PF10395.9 CCC70153.1 - 2.9e-236 786.3 39.3 3.5e-236 786.0 39.3 1.1 1 0 0 1 1 1 1 Utp8 family BBS2_Mid PF14783.6 CCC70153.1 - 0.014 15.4 0.1 0.84 9.7 0.0 3.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region TANGO2 PF05742.12 CCC70154.1 - 1.6e-59 202.0 0.0 1.9e-59 201.8 0.0 1.0 1 0 0 1 1 1 1 Transport and Golgi organisation 2 Abhydrolase_1 PF00561.20 CCC70156.1 - 3.9e-22 79.1 2.1 1.4e-21 77.3 2.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 CCC70156.1 - 2.9e-13 50.9 0.0 4.9e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 CCC70156.1 - 7.2e-07 28.7 0.0 2.1e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 CCC70156.1 - 1.7e-05 24.7 0.0 3.4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Acetyltransf_7 PF13508.7 CCC70157.1 - 5.7e-06 26.7 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 CCC70157.1 - 0.0037 17.2 0.1 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 CCC70157.1 - 0.0073 16.4 0.3 0.063 13.3 0.0 2.5 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 CCC70157.1 - 0.0099 16.1 0.0 0.048 13.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_13 PF13880.6 CCC70157.1 - 0.032 14.2 0.0 0.069 13.1 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase FR47 PF08445.10 CCC70157.1 - 0.05 13.6 0.0 0.16 12.0 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein TLD PF07534.16 CCC70157.1 - 0.086 13.1 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 TLD SURF1 PF02104.15 CCC70158.1 - 2.3e-43 148.5 0.1 3.3e-43 148.0 0.1 1.2 1 0 0 1 1 1 1 SURF1 family DASH_Dam1 PF08653.10 CCC70159.1 - 2.2e-25 88.2 0.1 5e-25 87.1 0.1 1.6 1 0 0 1 1 1 1 DASH complex subunit Dam1 LSM14 PF12701.7 CCC70160.1 - 4.3e-24 84.4 0.1 7.2e-24 83.7 0.1 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 CCC70160.1 - 9.5e-10 39.3 6.3 9.5e-10 39.3 6.3 2.6 3 0 0 3 3 3 1 FDF domain SM-ATX PF14438.6 CCC70160.1 - 0.0031 17.6 0.0 0.0066 16.6 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain FoP_duplication PF13865.6 CCC70160.1 - 9.6 6.8 25.5 4.5 7.9 18.7 2.5 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 LisH PF08513.11 CCC70161.1 - 1.7e-05 24.6 0.2 4.3e-05 23.3 0.2 1.7 1 0 0 1 1 1 1 LisH RNA_pol_RpbG PF16992.5 CCC70161.1 - 0.053 13.6 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase, subunit G WD40 PF00400.32 CCC70161.1 - 0.068 14.1 1.0 0.54 11.2 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Ribosom_S12_S23 PF00164.25 CCC70162.1 - 1.8e-51 172.5 0.3 2.3e-51 172.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Nup54 PF13874.6 CCC70163.1 - 6.7e-37 126.7 2.9 6.7e-37 126.7 2.9 3.1 3 1 1 4 4 4 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 CCC70163.1 - 5.4e-27 94.5 203.5 6.6e-11 42.9 38.6 5.3 1 1 5 6 6 6 6 Nucleoporin FG repeat region COG2 PF06148.11 CCC70164.1 - 6.3e-05 23.1 5.2 0.00071 19.7 5.2 2.7 1 1 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4208 PF13907.6 CCC70164.1 - 0.0045 17.4 0.5 0.011 16.2 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4208) Glu-tRNAGln PF02686.15 CCC70164.1 - 0.012 15.8 0.3 0.048 14.0 0.3 2.0 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Sec5 PF15469.6 CCC70164.1 - 0.025 14.4 3.3 0.39 10.5 1.0 2.4 1 1 1 2 2 2 0 Exocyst complex component Sec5 PhaP_Bmeg PF09602.10 CCC70164.1 - 0.087 12.8 3.4 0.48 10.3 3.4 2.3 1 1 0 1 1 1 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) SAS4 PF15460.6 CCC70164.1 - 0.14 12.3 1.4 0.59 10.3 0.5 2.4 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF948 PF06103.11 CCC70164.1 - 0.35 11.2 3.3 0.31 11.3 0.6 2.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Casc1_N PF15927.5 CCC70164.1 - 0.92 9.2 3.6 3.2 7.4 3.6 2.0 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Syntaxin_2 PF14523.6 CCC70164.1 - 1.6 9.1 7.6 2.1e+02 2.3 7.6 2.9 1 1 0 1 1 1 0 Syntaxin-like protein Sulfate_transp PF00916.20 CCC70165.1 - 6.5e-83 278.6 25.0 9.6e-83 278.0 25.0 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 CCC70165.1 - 1.2e-14 53.9 0.9 2.7e-14 52.8 0.9 1.6 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 CCC70165.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain zf-CCHC PF00098.23 CCC70166.1 - 8.1e-06 25.7 0.9 8.1e-06 25.7 0.9 1.7 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.6 CCC70166.1 - 0.00094 19.8 0.0 0.002 18.7 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 CCC70166.1 - 0.00095 19.7 0.0 0.0017 18.9 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease zf-CCHC_5 PF14787.6 CCC70166.1 - 0.014 15.1 0.8 0.029 14.1 0.8 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 CCC70166.1 - 0.02 15.3 0.2 0.036 14.5 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.6 CCC70166.1 - 0.11 12.4 0.6 0.18 11.7 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle DUF5355 PF17306.2 CCC70167.1 - 9e-101 337.2 14.8 9e-101 337.2 14.8 1.3 1 1 0 1 1 1 1 Family of unknown function (DUF5355) Cyclin_N PF00134.23 CCC70168.1 - 1.6e-37 128.0 0.1 4.6e-37 126.6 0.1 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCC70168.1 - 5.5e-19 68.4 0.0 1.5e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 CCC70169.1 - 2.1e-39 134.2 0.2 2.2e-38 130.9 0.1 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCC70169.1 - 6.3e-32 110.2 0.1 1.9e-31 108.6 0.0 1.9 2 0 0 2 2 2 1 Cyclin, C-terminal domain ATP-synt_S1 PF05827.12 CCC70170.1 - 0.0029 17.5 2.2 0.012 15.5 2.2 2.1 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DUF3397 PF11877.8 CCC70170.1 - 0.038 14.2 1.0 0.038 14.2 1.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3397) Orf78 PF06024.12 CCC70170.1 - 0.052 13.9 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF2951 PF11166.8 CCC70170.1 - 0.056 13.7 0.6 0.11 12.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) VMA21 PF09446.10 CCC70171.1 - 3.5e-12 46.2 14.4 2.8e-11 43.4 14.4 1.9 1 1 0 1 1 1 1 VMA21-like domain MscS_TM PF12794.7 CCC70171.1 - 0.037 12.9 0.0 0.037 12.9 0.0 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Med18 PF09637.10 CCC70172.1 - 6.9e-54 183.3 0.5 7.8e-54 183.1 0.5 1.0 1 0 0 1 1 1 1 Med18 protein SRTM1 PF15872.5 CCC70172.1 - 0.099 12.8 0.3 0.17 12.0 0.3 1.4 1 0 0 1 1 1 0 Serine-rich and transmembrane domain-containing protein 1 Pescadillo_N PF06732.11 CCC70173.1 - 4.2e-122 407.0 0.6 4.2e-122 407.0 0.6 2.1 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 CCC70173.1 - 1.7e-09 38.0 0.0 4.7e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CCC70173.1 - 0.0042 17.4 0.0 0.017 15.5 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 CCC70173.1 - 0.014 15.7 0.0 0.17 12.2 0.0 2.7 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Rhomboid PF01694.22 CCC70175.1 - 4.6e-32 111.1 16.2 7.7e-32 110.4 16.2 1.4 1 0 0 1 1 1 1 Rhomboid family DUF5516 PF17637.2 CCC70175.1 - 4.3 7.2 7.0 1.4 8.7 1.4 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5516) RabGAP-TBC PF00566.18 CCC70176.1 - 2e-52 178.0 0.2 2e-52 178.0 0.2 2.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.20 CCC70176.1 - 2.7e-16 59.5 0.2 7.6e-16 58.0 0.2 1.8 1 0 0 1 1 1 1 GRAM domain EF-hand_6 PF13405.6 CCC70176.1 - 6.7e-06 25.6 0.6 0.0012 18.6 0.1 3.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 CCC70176.1 - 0.00041 20.8 0.5 0.0099 16.3 0.9 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 CCC70176.1 - 0.0049 16.3 0.0 0.023 14.3 0.0 2.3 1 0 0 1 1 1 1 EF hand Telomere_reg-2 PF10193.9 CCC70177.1 - 4e-26 91.6 1.8 7e-24 84.4 0.0 3.5 3 1 0 3 3 3 2 Telomere length regulation protein HH_signal PF01085.18 CCC70177.1 - 0.14 11.9 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Peptidase_C50 PF03568.17 CCC70178.1 - 1.7e-130 435.8 0.1 1.7e-130 435.8 0.1 1.8 2 0 0 2 2 2 1 Peptidase family C50 CHAT PF12770.7 CCC70178.1 - 0.094 12.1 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 CHAT domain POX PF07526.11 CCC70178.1 - 0.12 13.0 0.7 0.33 11.5 0.1 2.1 2 0 0 2 2 2 0 Associated with HOX Flavin_Reduct PF01613.18 CCC70179.1 - 4.9e-30 104.6 0.0 6.4e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Mito_carr PF00153.27 CCC70181.1 - 1.5e-57 191.5 4.4 1.9e-18 66.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 CCC70181.1 - 0.019 14.1 1.3 0.78 8.8 0.2 2.9 2 1 0 3 3 3 0 Gammaproteobacterial serine protease NLRC4_HD PF17889.1 CCC70181.1 - 0.06 13.7 0.2 0.12 12.7 0.2 1.5 1 0 0 1 1 1 0 NLRC4 helical domain RNase_PH PF01138.21 CCC70182.1 - 2e-17 63.9 0.1 3.3e-17 63.2 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCC70182.1 - 2.8e-06 27.3 0.6 7.4e-06 25.9 0.6 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 tRNA-synt_1 PF00133.22 CCC70183.1 - 7.1e-221 734.6 0.5 9.1e-220 731.0 0.5 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCC70183.1 - 5.7e-31 107.5 1.4 1.6e-30 106.1 1.4 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CCC70183.1 - 3e-16 59.2 0.5 7.4e-08 31.5 0.0 4.9 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 CCC70183.1 - 9.3e-10 38.3 0.2 8.8e-07 28.6 0.1 2.8 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 CCC70183.1 - 3e-07 30.6 2.2 1.2e-06 28.7 2.2 2.2 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.19 CCC70183.1 - 0.00058 19.3 0.1 0.079 12.3 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1b PF00579.25 CCC70183.1 - 0.29 10.4 2.7 2.9 7.1 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) CwfJ_C_1 PF04677.15 CCC70184.1 - 3.1e-31 107.8 0.0 7e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 CCC70184.1 - 9.6e-18 64.9 0.3 2.4e-17 63.6 0.3 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.25 CCC70185.1 - 1.3e-56 191.9 0.0 1e-55 189.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70185.1 - 6.1e-28 97.8 0.5 1.6e-19 70.2 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CCC70185.1 - 0.00014 21.0 0.4 0.00031 19.8 0.4 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 CCC70185.1 - 0.0012 19.5 1.8 0.0042 17.8 1.5 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 CCC70185.1 - 0.0014 18.0 0.0 0.01 15.2 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 CCC70185.1 - 0.0018 17.7 0.0 0.0041 16.5 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCC70185.1 - 0.17 11.8 0.1 0.57 10.1 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Nop PF01798.18 CCC70186.1 - 1.1e-65 221.4 1.7 1.1e-65 221.4 1.7 1.6 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 CCC70186.1 - 3e-27 95.9 5.2 3e-27 95.9 5.2 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain Nrap_D5 PF17406.2 CCC70187.1 - 2e-54 183.7 0.0 1.3e-53 181.1 0.0 2.3 3 0 0 3 3 3 1 Nrap protein PAP/OAS1-like domain 5 Nrap_D2 PF17403.2 CCC70187.1 - 7.6e-52 175.1 2.0 6.6e-50 168.8 1.0 2.5 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D4 PF17405.2 CCC70187.1 - 6.5e-51 172.7 0.1 1.1e-50 171.9 0.1 1.4 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap PF03813.14 CCC70187.1 - 5.7e-44 149.8 5.1 5.7e-44 149.8 5.1 2.2 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D3 PF17404.2 CCC70187.1 - 1.1e-39 136.1 0.0 2.7e-39 134.8 0.0 1.7 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap_D6 PF17407.2 CCC70187.1 - 1.8e-29 102.6 0.2 5.1e-29 101.2 0.2 1.8 1 0 0 1 1 1 1 Nrap protein domain 6 MitMem_reg PF13012.6 CCC70187.1 - 0.52 10.8 3.0 6.6 7.2 0.0 3.3 3 0 0 3 3 3 0 Maintenance of mitochondrial structure and function DUF4611 PF15387.6 CCC70187.1 - 2 8.7 8.1 5.3 7.3 8.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Lipoprotein_20 PF13942.6 CCC70188.1 - 0.00064 19.7 0.5 0.00064 19.7 0.5 3.6 2 1 1 3 3 3 1 YfhG lipoprotein DUF1664 PF07889.12 CCC70188.1 - 0.036 14.1 26.6 0.52 10.3 4.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Cluap1 PF10234.9 CCC70188.1 - 5 6.4 35.6 0.2 11.0 10.0 3.4 2 1 1 3 3 3 0 Clusterin-associated protein-1 Catalase PF00199.19 CCC70189.1 - 1.4e-164 547.8 4.3 2.7e-164 546.9 4.3 1.4 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.12 CCC70189.1 - 1.1e-12 47.9 0.7 3.5e-12 46.4 0.0 2.2 3 0 0 3 3 3 1 Catalase-related immune-responsive AglB_L1 PF18079.1 CCC70189.1 - 0.13 12.6 0.1 0.37 11.1 0.1 1.8 1 0 0 1 1 1 0 Archaeal glycosylation protein B long peripheral domain Pil1 PF13805.6 CCC70190.1 - 1.9e-121 404.6 0.2 2.3e-121 404.3 0.2 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3268 PF11672.8 CCC70191.1 - 0.095 13.0 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 zinc-finger-containing domain IF-2B PF01008.17 CCC70192.1 - 2.9e-105 351.5 0.1 2.9e-105 351.5 0.1 2.1 2 0 0 2 2 2 1 Initiation factor 2 subunit family DeoRC PF00455.22 CCC70192.1 - 0.00012 22.0 0.9 0.0047 16.9 0.9 2.6 1 1 0 1 1 1 1 DeoR C terminal sensor domain SEEEED PF14797.6 CCC70192.1 - 0.019 15.1 6.9 0.019 15.1 6.9 2.5 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex STb_secrete PF09075.10 CCC70192.1 - 0.14 12.3 0.2 0.98 9.5 0.1 2.2 2 0 0 2 2 2 0 Heat-stable enterotoxin B, secretory Abi_2 PF07751.11 CCC70192.1 - 0.54 10.5 8.3 0.66 10.2 4.3 2.7 3 0 0 3 3 3 0 Abi-like protein DDHD PF02862.17 CCC70192.1 - 1 9.5 12.4 15 5.7 0.1 2.4 2 0 0 2 2 2 0 DDHD domain Sulfotransfer_2 PF03567.14 CCC70192.1 - 1.7 8.5 7.2 0.15 11.9 1.3 2.1 2 0 0 2 2 2 0 Sulfotransferase family MAS20 PF02064.15 CCC70193.1 - 4e-37 127.2 1.1 6e-37 126.6 1.1 1.1 1 0 0 1 1 1 1 MAS20 protein import receptor Nif11 PF07862.11 CCC70193.1 - 0.56 10.6 3.9 1.8 9.0 1.1 2.8 1 1 2 3 3 3 0 Nif11 domain SLX9 PF15341.6 CCC70194.1 - 1.1e-23 84.0 12.3 1.8e-23 83.4 12.3 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 Spore_II_R PF09551.10 CCC70194.1 - 0.56 10.7 3.2 0.62 10.5 0.7 2.1 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) PEX11 PF05648.14 CCC70195.1 - 2.1e-58 197.4 3.6 2.4e-58 197.2 3.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Med31 PF05669.12 CCC70195.1 - 0.081 12.9 0.4 0.19 11.7 0.4 1.7 1 0 0 1 1 1 0 SOH1 Sld5 PF05916.11 CCC70196.1 - 1.3e-19 70.7 0.0 1.7e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein AAA PF00004.29 CCC70197.1 - 1.7e-54 183.8 0.0 6.1e-45 152.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC70197.1 - 2.3e-07 30.5 0.0 0.0029 17.4 0.0 2.6 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 CCC70197.1 - 8.6e-05 22.7 0.0 0.00027 21.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCC70197.1 - 0.00016 21.4 0.0 0.00059 19.6 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Parvo_NS1 PF01057.17 CCC70197.1 - 0.00047 19.3 0.1 0.0013 17.9 0.0 1.7 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_22 PF13401.6 CCC70197.1 - 0.00059 20.1 0.0 0.076 13.3 0.0 3.4 3 1 1 4 4 3 1 AAA domain AAA_16 PF13191.6 CCC70197.1 - 0.00079 19.9 0.0 0.1 13.0 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 CCC70197.1 - 0.0017 18.7 0.0 0.0064 16.9 0.0 2.1 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 CCC70197.1 - 0.0018 17.8 0.0 0.0075 15.8 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 CCC70197.1 - 0.0037 17.3 0.0 0.019 15.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 CCC70197.1 - 0.01 15.6 0.0 0.031 14.0 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 CCC70197.1 - 0.012 14.9 0.2 0.032 13.5 0.0 1.7 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase PF06745.13 CCC70197.1 - 0.015 14.6 0.0 0.037 13.4 0.0 1.6 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.21 CCC70197.1 - 0.02 14.3 0.1 0.04 13.3 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CCC70197.1 - 0.035 14.7 0.0 0.087 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 CCC70197.1 - 0.036 14.1 0.0 0.093 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CCC70197.1 - 0.046 13.3 0.2 0.69 9.4 0.0 2.7 2 1 1 3 3 3 0 AAA domain Glu_cys_ligase PF04262.14 CCC70197.1 - 0.069 11.8 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase TsaE PF02367.17 CCC70197.1 - 0.11 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pam16 PF03656.13 CCC70198.1 - 0.0099 15.9 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.31 CCC70198.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain DGC PF08859.11 CCC70199.1 - 0.14 12.3 1.7 1.2 9.3 0.1 2.9 2 1 2 4 4 4 0 DGC domain DHHC PF01529.20 CCC70200.1 - 1e-35 122.8 14.2 1e-35 122.8 14.2 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Pox_A14 PF05767.12 CCC70200.1 - 0.052 13.7 2.4 1.1 9.5 0.7 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DPM3 PF08285.11 CCC70200.1 - 5.8 7.2 12.0 0.77 10.0 3.9 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Syja_N PF02383.18 CCC70201.1 - 3e-77 260.1 2.0 3.6e-77 259.8 0.0 2.0 2 0 0 2 2 2 1 SacI homology domain KRE1 PF17056.5 CCC70202.1 - 1.3e-23 82.4 9.2 1.3e-23 82.4 9.2 5.8 5 2 0 6 6 6 2 Killer toxin-resistance protein 1 Na_Ca_ex PF01699.24 CCC70203.1 - 2.4e-18 66.5 47.3 3.1e-14 53.2 11.8 4.1 4 1 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 CCC70203.1 - 4.3e-14 52.9 8.3 4.3e-14 52.9 8.3 4.3 6 0 0 6 6 6 1 Inner membrane component domain LodA_N PF17990.1 CCC70203.1 - 0.17 11.8 1.7 1.8 8.4 0.3 2.3 2 0 0 2 2 2 0 L-Lysine epsilon oxidase N-terminal Hydrolase_4 PF12146.8 CCC70204.1 - 4.6e-14 52.3 0.0 5.7e-09 35.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 CCC70204.1 - 1.6e-08 34.3 0.0 1.2e-07 31.5 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 CCC70204.1 - 3.2e-08 33.6 0.0 1.8e-06 27.8 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.11 CCC70204.1 - 5.7e-05 23.1 0.0 0.00082 19.4 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 CCC70204.1 - 0.00042 20.0 0.0 0.00066 19.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.12 CCC70204.1 - 0.015 14.2 0.4 0.024 13.6 0.4 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DUF1057 PF06342.12 CCC70204.1 - 0.022 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Esterase PF00756.20 CCC70204.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF1749 PF08538.10 CCC70204.1 - 0.13 11.3 0.0 0.44 9.6 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.7 CCC70204.1 - 0.21 12.1 0.0 0.27 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.24 CCC70205.1 - 1.5e-116 390.0 34.4 1.7e-116 389.8 34.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC70205.1 - 7.4e-19 67.9 35.5 8.7e-18 64.4 33.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PDT PF00800.18 CCC70206.1 - 1.2e-54 184.9 0.3 1.5e-54 184.6 0.3 1.1 1 0 0 1 1 1 1 Prephenate dehydratase DUF436 PF04260.12 CCC70206.1 - 0.013 15.1 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF436) ACT PF01842.25 CCC70206.1 - 0.057 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 ACT domain DNA_pol_E_B PF04042.16 CCC70206.1 - 0.076 12.3 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B ATP11 PF06644.11 CCC70207.1 - 2.1e-88 296.6 1.6 2.4e-88 296.5 1.6 1.0 1 0 0 1 1 1 1 ATP11 protein Sigma70_r1_1 PF03979.14 CCC70207.1 - 0.018 15.1 3.2 0.037 14.1 3.2 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 CRR7 PF12095.8 CCC70207.1 - 0.12 12.9 1.8 0.33 11.4 1.8 1.7 1 0 0 1 1 1 0 Protein CHLORORESPIRATORY REDUCTION 7 Exonuc_X-T_C PF08411.10 CCC70207.1 - 0.13 11.4 3.0 0.2 10.8 3.0 1.3 1 0 0 1 1 1 0 Exonuclease C-terminal DUF2115 PF09888.9 CCC70207.1 - 0.13 12.8 1.9 0.28 11.7 1.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Prenyltransf PF01255.19 CCC70208.1 - 7.3e-75 251.3 0.0 9.4e-75 251.0 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Pyrophosphatase PF00719.19 CCC70209.1 - 2.8e-58 196.3 0.3 3.8e-58 195.8 0.3 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase PRAI PF00697.22 CCC70210.1 - 7.7e-60 202.0 0.1 8.8e-60 201.8 0.1 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Dimeth_Pyl PF09505.10 CCC70210.1 - 0.0047 15.5 0.0 0.76 8.2 0.0 2.2 1 1 1 2 2 2 2 Dimethylamine methyltransferase (Dimeth_PyL) FMN_dh PF01070.18 CCC70210.1 - 0.01 14.9 0.6 1.1 8.2 0.0 2.4 2 1 0 2 2 2 0 FMN-dependent dehydrogenase Histone PF00125.24 CCC70211.1 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CCC70211.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CCC70211.1 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CCC70211.1 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CCC70211.1 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CCC70211.1 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CCC70212.1 - 1.9e-09 37.6 0.1 2.2e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCC70212.1 - 2.1e-05 24.9 0.1 2.5e-05 24.7 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CCC70212.1 - 3e-05 24.1 0.1 4.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CCC70212.1 - 3.6e-05 24.0 0.1 6.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CCC70212.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CCC70212.1 - 0.0029 17.7 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CCC70212.1 - 0.0067 16.4 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 CCC70212.1 - 0.043 14.3 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Tcp11 PF05794.13 CCC70213.1 - 7.1e-94 315.4 3.3 1.2e-93 314.6 3.3 1.3 1 0 0 1 1 1 1 T-complex protein 11 Sel1 PF08238.12 CCC70214.1 - 7.9e-10 39.1 4.2 1.9e-07 31.5 0.1 3.3 3 0 0 3 3 3 3 Sel1 repeat Aldedh PF00171.22 CCC70215.1 - 1.3e-158 528.3 0.1 1.5e-158 528.1 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CCC70215.1 - 0.0011 18.4 0.0 0.0025 17.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) OmdA PF13376.6 CCC70215.1 - 0.11 12.5 0.2 0.28 11.2 0.2 1.6 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated RCR PF12273.8 CCC70216.1 - 0.79 10.4 0.0 0.79 10.4 0.0 2.2 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red Mannosyl_trans2 PF04188.13 CCC70217.1 - 2.8e-79 267.5 33.7 2.3e-62 211.8 23.2 2.0 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V) DUF2070 PF09843.9 CCC70217.1 - 2.1 6.5 12.5 2 6.6 3.4 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Ran_BP1 PF00638.18 CCC70218.1 - 1.7e-53 180.1 1.8 2.7e-53 179.4 1.8 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.23 CCC70218.1 - 3e-06 27.2 1.3 1.7e-05 24.7 1.3 2.0 1 1 0 1 1 1 1 WH1 domain VID27_PH PF17747.1 CCC70218.1 - 0.11 12.8 0.1 0.41 10.9 0.1 2.0 1 1 0 1 1 1 0 VID27 PH-like domain Trehalase PF01204.18 CCC70219.1 - 1.8e-188 627.6 0.0 2.5e-188 627.1 0.0 1.2 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.11 CCC70219.1 - 1.6e-15 56.5 2.2 2.7e-15 55.8 2.2 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Dicty_REP PF05086.12 CCC70219.1 - 2 6.3 7.4 3 5.7 7.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1640 PF07798.11 CCC70220.1 - 7.1e-51 172.7 6.4 9.1e-51 172.4 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF5082 PF16888.5 CCC70220.1 - 0.0018 18.5 4.7 0.32 11.3 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF5082) FTA4 PF13093.6 CCC70220.1 - 0.025 14.5 5.5 0.03 14.2 5.5 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF1732 PF08340.11 CCC70220.1 - 0.048 13.6 4.0 0.11 12.5 4.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) FRG2 PF15315.6 CCC70220.1 - 0.079 13.2 0.1 0.15 12.2 0.1 1.4 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Uso1_p115_C PF04871.13 CCC70220.1 - 0.11 12.9 5.9 0.072 13.5 2.8 2.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region XhlA PF10779.9 CCC70220.1 - 0.12 12.5 1.3 0.76 10.0 0.0 2.4 2 0 0 2 2 2 0 Haemolysin XhlA FapA PF03961.13 CCC70220.1 - 0.17 10.4 7.4 0.21 10.1 7.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A FlaC_arch PF05377.11 CCC70220.1 - 0.22 12.0 2.1 20 5.7 0.1 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Sulfatase_C PF14707.6 CCC70220.1 - 0.23 12.2 0.7 11 6.7 0.0 2.4 1 1 1 2 2 2 0 C-terminal region of aryl-sulfatase SLATT_fungal PF18142.1 CCC70220.1 - 0.37 10.8 3.8 2.5 8.1 0.1 2.5 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain DUF4200 PF13863.6 CCC70220.1 - 1 9.8 10.8 3.1 8.2 10.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Phage_lysis PF03245.13 CCC70220.1 - 1.1 9.4 8.4 0.24 11.5 1.5 2.2 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein DUF745 PF05335.13 CCC70220.1 - 2 8.1 4.9 0.41 10.4 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Fib_alpha PF08702.10 CCC70220.1 - 4.1 7.6 9.9 5.3 7.2 5.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YlqD PF11068.8 CCC70220.1 - 5.7 7.3 10.1 55 4.1 9.9 2.1 1 1 0 1 1 1 0 YlqD protein DUF1664 PF07889.12 CCC70220.1 - 7.2 6.7 8.1 12 6.0 1.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) PMM PF03332.13 CCC70221.1 - 2.9e-113 377.1 0.4 3.3e-113 376.9 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 CCC70221.1 - 0.00014 21.7 0.0 0.0028 17.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.13 CCC70221.1 - 0.079 12.2 0.1 0.1 11.8 0.1 1.1 1 0 0 1 1 1 0 TMPIT-like protein HAD PF12710.7 CCC70221.1 - 0.093 13.1 0.4 4.7 7.6 0.0 2.5 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCC70221.1 - 0.17 12.1 0.0 0.31 11.3 0.0 1.6 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase USP8_dimer PF08969.11 CCC70222.1 - 7.9e-08 32.5 1.9 1.2e-07 31.9 0.9 1.9 1 1 0 1 1 1 1 USP8 dimerisation domain VASt PF16016.5 CCC70223.1 - 8.3e-32 110.7 2.2 2.3e-31 109.3 2.2 1.7 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CCC70223.1 - 2.5e-24 85.3 0.3 7.4e-24 83.8 0.3 1.8 1 0 0 1 1 1 1 GRAM domain SPC22 PF04573.12 CCC70224.1 - 1.1e-55 187.7 1.9 1.4e-55 187.4 1.9 1.1 1 0 0 1 1 1 1 Signal peptidase subunit Sugar_tr PF00083.24 CCC70225.1 - 7.1e-71 239.4 25.1 3e-70 237.4 25.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC70225.1 - 3e-22 79.0 30.9 4.5e-19 68.6 13.3 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily VIT1 PF01988.19 CCC70225.1 - 0.055 13.3 8.2 0.82 9.5 0.1 2.7 2 0 0 2 2 2 0 VIT family Pkinase PF00069.25 CCC70226.1 - 1.4e-53 182.0 2.8 7.1e-52 176.4 2.8 2.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70226.1 - 8e-31 107.3 0.0 1.1e-29 103.5 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC70226.1 - 0.012 14.4 0.0 0.023 13.5 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 CCC70226.1 - 0.11 12.4 0.1 0.63 9.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family CCDC-167 PF15188.6 CCC70226.1 - 0.82 10.1 6.1 0.28 11.5 2.9 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SH3_1 PF00018.28 CCC70227.1 - 2.8e-10 39.6 0.2 1.4e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 CCC70227.1 - 0.034 14.0 0.0 0.12 12.3 0.0 2.0 1 0 0 1 1 1 0 Variant SH3 domain HEAT PF02985.22 CCC70228.1 - 4.8e-19 66.8 3.7 0.0022 18.1 0.0 7.8 8 0 0 8 8 8 3 HEAT repeat HEAT_EZ PF13513.6 CCC70228.1 - 6.3e-19 68.1 0.2 2.7e-11 43.7 0.0 6.4 6 0 0 6 6 6 2 HEAT-like repeat HEAT_2 PF13646.6 CCC70228.1 - 8.2e-12 45.4 0.0 0.00022 21.5 0.0 6.1 6 1 1 7 7 7 3 HEAT repeats Cnd1 PF12717.7 CCC70228.1 - 2e-05 24.7 0.5 0.011 15.8 0.0 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CCC70228.1 - 0.00078 20.0 0.0 0.77 10.4 0.0 4.3 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 CCC70228.1 - 0.0011 18.8 0.2 0.011 15.6 0.0 2.8 2 1 0 2 2 2 1 Importin-beta N-terminal domain DRIM PF07539.12 CCC70228.1 - 0.011 14.0 0.2 0.59 8.4 0.1 2.6 2 1 1 3 3 3 0 Down-regulated in metastasis Beta_helix_2 PF18835.1 CCC70228.1 - 0.097 12.4 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Beta helix repeat of Inulin fructotransferase DUF3437 PF11919.8 CCC70228.1 - 0.14 12.1 0.0 13 5.8 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) ANAPC15 PF15243.6 CCC70228.1 - 0.32 11.4 3.8 0.3 11.5 1.6 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 Mannosyl_trans3 PF11051.8 CCC70229.1 - 9.2e-83 277.8 0.6 7.7e-82 274.7 0.0 2.3 3 0 0 3 3 3 1 Mannosyltransferase putative Glutaredoxin PF00462.24 CCC70230.1 - 3.8e-11 43.0 0.0 7.8e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin DUF4179 PF13786.6 CCC70230.1 - 0.0093 16.4 0.1 0.015 15.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4179) Thioredoxin_2 PF13098.6 CCC70230.1 - 0.022 15.2 0.0 0.84 10.1 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 CCC70230.1 - 0.16 12.2 0.0 0.33 11.1 0.0 1.7 2 0 0 2 2 2 0 Thioredoxin-like CSG2 PF16965.5 CCC70231.1 - 2.9e-188 625.8 11.8 3.2e-188 625.6 11.8 1.0 1 0 0 1 1 1 1 Ceramide synthase regulator SCO1-SenC PF02630.14 CCC70232.1 - 3.6e-46 156.4 0.0 5.1e-46 155.9 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 CCC70232.1 - 5.9e-05 23.0 0.0 0.00088 19.2 0.0 2.4 2 1 0 2 2 2 1 AhpC/TSA family ABC2_membrane PF01061.24 CCC70233.1 - 4.5e-62 209.2 63.4 4.7e-39 134.0 14.6 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CCC70233.1 - 1.3e-38 132.6 0.0 5.9e-18 65.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCC70233.1 - 1.7e-34 117.6 8.0 2.2e-32 110.8 0.0 3.9 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.6 CCC70233.1 - 1.1e-08 35.6 0.1 3.9e-08 33.8 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 CCC70233.1 - 2.5e-06 26.9 8.0 2.5e-06 26.9 8.0 3.8 3 1 1 4 4 3 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CCC70233.1 - 6.2e-06 26.2 0.0 0.00055 19.9 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CCC70233.1 - 5.9e-05 23.5 0.2 0.0022 18.4 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 CCC70233.1 - 0.00024 21.7 0.1 0.0024 18.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCC70233.1 - 0.0033 17.7 0.3 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CCC70233.1 - 0.0034 17.4 0.4 0.25 11.4 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 CCC70233.1 - 0.0055 16.3 0.1 0.012 15.2 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CCC70233.1 - 0.006 16.3 0.1 0.23 11.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 CCC70233.1 - 0.0096 15.8 0.0 4.6 7.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCC70233.1 - 0.0097 15.4 0.0 0.58 9.6 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 CCC70233.1 - 0.019 15.4 0.0 2.7 8.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 CCC70233.1 - 0.029 14.6 0.0 0.071 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 CCC70233.1 - 0.036 14.5 0.0 0.16 12.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 CCC70233.1 - 0.062 13.2 0.0 0.54 10.2 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_25 PF13481.6 CCC70233.1 - 0.075 12.6 0.2 0.19 11.3 0.1 1.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CCC70233.1 - 0.089 12.5 0.3 0.59 9.8 0.0 2.4 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 CCC70233.1 - 0.13 12.3 0.1 0.61 10.1 0.1 2.0 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CCC70233.1 - 0.16 12.2 0.0 0.42 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 CCC70233.1 - 0.25 11.0 0.5 3.8 7.2 0.2 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 CCC70234.1 - 6e-65 218.6 57.3 1.8e-40 138.6 15.8 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CCC70234.1 - 5.9e-38 130.5 0.0 6.9e-18 65.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCC70234.1 - 2.3e-37 126.8 10.5 4.6e-33 113.0 0.0 3.7 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CCC70234.1 - 1.5e-09 37.5 7.3 1.5e-09 37.5 7.3 2.8 2 1 0 2 2 2 1 ABC-2 family transporter protein ABC_trans_N PF14510.6 CCC70234.1 - 2.3e-07 31.3 0.3 6.3e-07 29.9 0.0 2.0 2 0 0 2 2 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 CCC70234.1 - 3.4e-06 27.0 0.1 0.00059 19.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 CCC70234.1 - 3.2e-05 23.9 0.0 0.037 13.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CCC70234.1 - 0.00012 22.5 0.2 0.004 17.5 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 CCC70234.1 - 0.0022 18.1 0.0 0.1 12.7 0.0 2.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CCC70234.1 - 0.003 17.8 0.0 0.013 15.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 CCC70234.1 - 0.0036 17.0 0.1 0.1 12.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.19 CCC70234.1 - 0.0054 16.2 0.0 0.96 8.8 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain cobW PF02492.19 CCC70234.1 - 0.0096 15.5 0.1 0.022 14.4 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CCC70234.1 - 0.014 15.9 0.0 0.064 13.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain TrpP PF17099.5 CCC70234.1 - 0.059 13.1 1.3 1.1 9.1 0.1 2.3 2 0 0 2 2 2 0 Tryptophan transporter TrpP AAA_30 PF13604.6 CCC70234.1 - 0.063 13.0 0.3 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 CCC70234.1 - 0.068 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CCC70234.1 - 0.085 12.4 0.1 0.32 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CCC70234.1 - 0.11 12.8 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 CCC70234.1 - 0.15 12.1 0.1 0.67 10.0 0.0 2.2 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.12 CCC70234.1 - 0.26 11.2 0.5 0.59 10.0 0.1 1.8 2 0 0 2 2 1 0 NACHT domain ABC2_membrane PF01061.24 CCC70235.1 - 1.2e-59 201.2 61.3 3.8e-36 124.5 14.1 3.1 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.12 CCC70235.1 - 1.9e-37 127.0 10.4 2.4e-32 110.7 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.27 CCC70235.1 - 7e-36 123.8 0.0 3e-17 63.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.6 CCC70235.1 - 3.9e-08 33.8 2.1 4.2e-08 33.7 0.2 2.1 2 0 0 2 2 2 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 CCC70235.1 - 2.2e-07 30.3 3.7 2.2e-07 30.3 3.7 2.9 2 1 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CCC70235.1 - 8.7e-06 25.7 0.0 0.00087 19.2 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 CCC70235.1 - 0.00016 21.6 0.0 0.17 11.6 0.0 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CCC70235.1 - 0.0004 20.8 0.4 0.0068 16.8 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.23 CCC70235.1 - 0.0041 17.2 0.2 0.15 12.2 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CCC70235.1 - 0.0058 16.9 0.2 0.022 15.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCC70235.1 - 0.01 16.4 0.0 0.083 13.4 0.0 2.4 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 CCC70235.1 - 0.012 15.3 0.1 0.024 14.2 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 CCC70235.1 - 0.014 15.1 0.1 0.22 11.3 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 CCC70235.1 - 0.04 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 CCC70235.1 - 0.041 13.3 0.0 0.96 8.8 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain RNA_helicase PF00910.22 CCC70235.1 - 0.073 13.5 0.0 3.1 8.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.6 CCC70235.1 - 0.11 12.2 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CCC70235.1 - 0.12 12.6 0.0 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CCC70235.1 - 0.12 12.0 0.0 0.4 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CCC70235.1 - 0.23 11.4 0.6 0.5 10.3 0.1 1.8 2 0 0 2 2 1 0 NACHT domain GalKase_gal_bdg PF10509.9 CCC70236.1 - 1.5e-20 72.4 0.0 3.4e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 CCC70236.1 - 1.1e-14 54.3 1.4 2.5e-14 53.3 1.4 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 CCC70236.1 - 1.5e-13 50.9 0.0 4e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal DUF1748 PF08520.10 CCC70236.1 - 0.012 15.5 0.0 0.032 14.1 0.0 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1748) FRB_dom PF08771.11 CCC70236.1 - 0.18 12.3 0.2 0.52 10.8 0.2 1.8 1 0 0 1 1 1 0 FKBP12-rapamycin binding domain HTH_23 PF13384.6 CCC70236.1 - 0.2 11.5 0.1 0.76 9.6 0.0 2.0 2 0 0 2 2 2 0 Homeodomain-like domain Aldose_epim PF01263.20 CCC70237.1 - 7.4e-80 268.5 0.2 9.7e-80 268.1 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase GDP_Man_Dehyd PF16363.5 CCC70237.1 - 2.3e-57 194.9 0.0 3.2e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 CCC70237.1 - 5.8e-54 183.1 0.0 1.4e-53 181.8 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 CCC70237.1 - 1.7e-17 63.5 0.0 1.2e-15 57.4 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 CCC70237.1 - 1.2e-14 54.0 0.0 3.1e-14 52.6 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 CCC70237.1 - 3.7e-11 42.7 0.0 6.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 CCC70237.1 - 4.2e-07 29.6 0.0 6.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CCC70237.1 - 2.7e-06 27.4 0.0 4.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 CCC70237.1 - 3.2e-06 26.5 0.0 2.6e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CCC70237.1 - 0.0021 18.0 0.0 0.0034 17.3 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GalP_UDP_tr_C PF02744.17 CCC70238.1 - 5.2e-68 228.0 0.3 1.2e-67 226.8 0.1 1.6 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 CCC70238.1 - 7.7e-68 228.5 0.2 1.1e-67 228.0 0.2 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4921 PF16268.5 CCC70238.1 - 0.0023 16.8 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4921) HIT PF01230.23 CCC70238.1 - 0.043 14.5 0.2 0.31 11.8 0.0 2.4 3 0 0 3 3 3 0 HIT domain DUF3721 PF12518.8 CCC70238.1 - 0.37 10.7 1.6 0.9 9.4 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function ParA PF10609.9 CCC70239.1 - 2e-96 322.2 0.0 2.3e-96 322.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 CCC70239.1 - 7.9e-10 38.9 0.0 6e-09 36.0 0.0 2.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CCC70239.1 - 2.2e-08 34.2 0.5 1.8e-07 31.2 0.5 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 CCC70239.1 - 1.8e-07 30.7 0.0 6.9e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 CCC70239.1 - 1.5e-05 24.4 0.1 8.1e-05 22.0 0.1 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase MeaB PF03308.16 CCC70239.1 - 0.0032 16.5 0.1 0.006 15.6 0.1 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Fer4_NifH PF00142.18 CCC70239.1 - 0.0045 16.5 0.0 0.12 11.8 0.1 2.1 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 CCC70239.1 - 0.023 14.2 0.1 0.14 11.6 0.1 1.9 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ APS_kinase PF01583.20 CCC70239.1 - 0.036 14.0 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_25 PF13481.6 CCC70239.1 - 0.071 12.7 0.2 0.12 11.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 CCC70239.1 - 0.16 11.7 0.3 0.57 10.0 0.1 2.0 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Gti1_Pac2 PF09729.9 CCC70240.1 - 1.3e-47 162.3 0.4 1.3e-47 162.3 0.4 5.3 2 2 0 2 2 2 1 Gti1/Pac2 family AAA PF00004.29 CCC70241.1 - 8.1e-40 136.3 0.0 1.4e-39 135.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC70241.1 - 1.6e-07 31.0 0.1 3.2e-07 30.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 CCC70241.1 - 3.2e-07 30.2 0.2 4.6e-06 26.5 0.0 2.8 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 CCC70241.1 - 1.8e-05 24.9 0.0 3.6e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCC70241.1 - 3e-05 23.8 0.0 5.9e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 CCC70241.1 - 3.5e-05 24.1 0.2 0.00067 20.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CCC70241.1 - 0.00012 22.1 0.0 0.00066 19.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCC70241.1 - 0.0003 21.2 0.2 0.0022 18.4 0.2 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 CCC70241.1 - 0.00087 18.9 0.1 0.12 11.9 0.0 2.3 1 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 CCC70241.1 - 0.0019 17.5 0.1 0.0033 16.7 0.1 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 CCC70241.1 - 0.0029 17.6 0.0 0.01 15.9 0.0 1.9 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 CCC70241.1 - 0.0043 16.5 0.2 0.01 15.2 0.2 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CCC70241.1 - 0.0068 15.6 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CCC70241.1 - 0.0071 16.1 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 CCC70241.1 - 0.011 16.3 0.0 0.026 15.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 CCC70241.1 - 0.014 15.6 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 CCC70241.1 - 0.016 14.6 0.1 5.3 6.4 0.0 2.7 2 1 1 3 3 3 0 Bacterial TniB protein Guanylate_kin PF00625.21 CCC70241.1 - 0.034 13.8 0.5 1.3 8.7 0.0 3.2 4 0 0 4 4 3 0 Guanylate kinase NACHT PF05729.12 CCC70241.1 - 0.082 12.8 0.0 0.26 11.2 0.0 2.0 1 1 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 CCC70241.1 - 0.099 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CCC70241.1 - 0.11 11.7 0.3 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ATPase PF06745.13 CCC70241.1 - 0.15 11.4 0.2 4.4 6.6 0.0 2.2 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.26 CCC70241.1 - 0.17 11.6 0.0 0.42 10.3 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 CCC70241.1 - 0.18 12.0 0.2 0.82 9.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 CCC70241.1 - 0.2 11.1 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein SPX PF03105.19 CCC70241.1 - 4.1 7.2 29.4 0.3 11.0 7.0 2.3 2 0 0 2 2 2 0 SPX domain bZIP_1 PF00170.21 CCC70243.1 - 2.7e-09 37.0 12.5 4.6e-09 36.2 10.2 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 CCC70243.1 - 1.1e-05 25.5 8.5 1.1e-05 25.5 8.5 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 CCC70243.1 - 0.028 14.9 10.5 0.039 14.5 9.6 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF3195 PF11424.8 CCC70243.1 - 0.14 12.3 0.5 0.26 11.4 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) Streptin-Immun PF11083.8 CCC70243.1 - 1.5 9.3 6.8 0.42 11.1 3.0 2.0 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Erg28 PF03694.13 CCC70245.1 - 2.6e-44 150.1 2.6 3.4e-44 149.7 2.6 1.2 1 0 0 1 1 1 1 Erg28 like protein MtN3_slv PF03083.16 CCC70245.1 - 0.033 14.2 1.0 0.033 14.2 1.0 1.8 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange SNF2_N PF00176.23 CCC70246.1 - 4.8e-69 232.7 0.3 8.6e-69 231.9 0.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCC70246.1 - 2.3e-19 69.8 0.0 2e-18 66.7 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC70246.1 - 4.4e-09 36.6 1.4 1.2e-08 35.1 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCC70246.1 - 1.6e-06 28.0 0.0 7e-06 25.9 0.0 2.2 2 1 1 3 3 3 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CCC70246.1 - 0.002 17.4 0.8 0.005 16.1 0.0 2.1 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SWIRM PF04433.17 CCC70247.1 - 2.7e-27 94.9 0.5 8.6e-27 93.3 0.1 2.2 2 0 0 2 2 2 1 SWIRM domain ZZ PF00569.17 CCC70247.1 - 2.2e-13 49.8 3.3 3.4e-13 49.2 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM-assoc_1 PF16495.5 CCC70247.1 - 3e-09 36.7 7.3 3e-09 36.7 7.3 2.3 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 CCC70247.1 - 1.2e-08 35.0 0.1 2.4e-08 34.1 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCC70247.1 - 8e-06 26.0 0.4 0.00013 22.1 0.0 3.0 4 0 0 4 4 4 1 Myb-like DNA-binding domain zf-UBR PF02207.20 CCC70247.1 - 0.0052 16.9 1.4 0.0092 16.1 1.4 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DUF4428 PF14471.6 CCC70247.1 - 0.18 11.7 0.7 1 9.4 0.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) zf-CCHC_2 PF13696.6 CCC70247.1 - 0.6 10.0 5.6 2.4 8.1 0.8 2.4 2 0 0 2 2 2 0 Zinc knuckle STAG PF08514.11 CCC70248.1 - 2.6e-21 75.7 4.3 3.4e-21 75.3 0.3 3.2 3 0 0 3 3 3 1 STAG domain ANAPC_CDC26 PF10471.9 CCC70249.1 - 7e-08 33.2 3.0 1.3e-07 32.3 3.0 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 AbrB_C PF18277.1 CCC70249.1 - 0.15 11.7 0.2 0.31 10.7 0.2 1.5 1 0 0 1 1 1 0 AbrB C-terminal domain AA_permease PF00324.21 CCC70251.1 - 3.6e-36 124.8 9.0 4e-36 124.6 9.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC70251.1 - 5.6e-11 41.9 9.0 6.3e-11 41.7 9.0 1.0 1 0 0 1 1 1 1 Amino acid permease RNA_pol_A_bac PF01000.26 CCC70253.1 - 7.7e-32 110.0 0.1 1.9e-31 108.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 CCC70253.1 - 3.4e-18 64.8 0.0 4.5e-18 64.4 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GRP PF07172.11 CCC70255.1 - 0.68 10.7 19.2 0.41 11.4 16.4 2.1 2 0 0 2 2 2 0 Glycine rich protein family DUF4602 PF15375.6 CCC70255.1 - 4.9 7.5 21.5 0.12 12.7 1.4 3.1 2 2 1 3 3 3 0 Domain of unknown function (DUF4602) HLH PF00010.26 CCC70256.1 - 2.4e-12 46.6 0.6 6.5e-12 45.2 0.6 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UCR_hinge PF02320.16 CCC70257.1 - 1e-25 89.7 4.3 1.9e-25 88.9 4.3 1.5 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Cwf_Cwc_15 PF04889.12 CCC70257.1 - 0.0024 17.7 12.1 0.0027 17.5 12.1 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Sigma70_ner PF04546.13 CCC70257.1 - 0.028 14.3 8.0 0.028 14.3 8.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region FAM176 PF14851.6 CCC70257.1 - 0.039 13.6 4.8 0.044 13.5 4.8 1.2 1 0 0 1 1 1 0 FAM176 family NOA36 PF06524.12 CCC70257.1 - 0.051 12.9 9.6 0.058 12.7 9.6 1.3 1 0 0 1 1 1 0 NOA36 protein BSP_II PF05432.11 CCC70257.1 - 0.11 12.2 11.3 0.12 12.1 11.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Utp14 PF04615.13 CCC70257.1 - 0.13 10.8 6.9 0.15 10.6 6.9 1.0 1 0 0 1 1 1 0 Utp14 protein DNA_pol_phi PF04931.13 CCC70257.1 - 0.16 10.0 13.5 0.16 10.0 13.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Sporozoite_P67 PF05642.11 CCC70257.1 - 0.2 9.7 4.9 0.21 9.6 4.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.12 CCC70257.1 - 0.21 9.8 11.9 0.22 9.7 11.9 1.0 1 0 0 1 1 1 0 Nop14-like family YL1 PF05764.13 CCC70257.1 - 0.33 11.1 10.4 0.37 10.9 10.4 1.1 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 CCC70257.1 - 0.46 8.7 6.3 0.43 8.8 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein TLP-20 PF06088.11 CCC70257.1 - 0.74 9.7 3.5 0.91 9.4 3.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF2457 PF10446.9 CCC70257.1 - 0.83 8.7 14.0 0.82 8.8 14.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PGA2 PF07543.12 CCC70257.1 - 0.88 9.6 7.2 1.2 9.2 7.2 1.2 1 0 0 1 1 1 0 Protein trafficking PGA2 Rhabdo_ncap PF00945.18 CCC70257.1 - 0.91 8.3 3.8 1 8.1 3.8 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Radial_spoke PF04712.12 CCC70257.1 - 1.5 7.7 9.7 1.5 7.6 9.7 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein SDA1 PF05285.12 CCC70257.1 - 1.9 7.8 12.1 2.1 7.7 12.1 1.1 1 0 0 1 1 1 0 SDA1 TRAP_alpha PF03896.16 CCC70257.1 - 2.4 7.3 7.5 2.7 7.1 7.5 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RRN3 PF05327.11 CCC70257.1 - 3.4 6.1 7.0 3.3 6.2 7.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 GEN1_C PF18380.1 CCC70257.1 - 5.8 7.9 9.7 7.4 7.5 9.7 1.3 1 1 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain Pox_Ag35 PF03286.14 CCC70257.1 - 6.8 6.4 9.4 8.6 6.1 9.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Ribosomal_L29e PF01779.17 CCC70259.1 - 7.7e-24 83.7 9.4 1.1e-23 83.3 9.4 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family RRM_1 PF00076.22 CCC70260.1 - 5.4e-16 58.2 1.0 3.5e-07 30.0 0.1 3.8 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC70260.1 - 5.1e-05 23.3 0.0 0.24 11.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 CCC70260.1 - 0.00073 19.4 0.0 2 8.3 0.1 2.8 2 1 0 2 2 2 2 Occluded RNA-recognition motif SET_assoc PF11767.8 CCC70260.1 - 0.15 11.7 0.0 2.2 8.0 0.0 2.3 2 0 0 2 2 2 0 Histone lysine methyltransferase SET associated Ribosomal_L2_C PF03947.18 CCC70261.1 - 7.8e-45 152.1 3.0 1.4e-44 151.3 3.0 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CCC70261.1 - 1.1e-13 51.0 0.2 2.6e-13 49.7 0.2 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SMC_N PF02463.19 CCC70262.1 - 4.1e-69 232.4 17.9 6.1e-67 225.3 17.9 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 CCC70262.1 - 6.6e-18 65.1 0.3 1.9e-17 63.6 0.3 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_15 PF13175.6 CCC70262.1 - 5.7e-10 39.4 15.9 5.7e-10 39.4 15.9 4.3 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 CCC70262.1 - 8.1e-07 29.1 21.7 6.7e-05 22.8 0.8 3.8 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCC70262.1 - 4e-05 23.3 0.0 0.00014 21.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.6 CCC70262.1 - 8.6e-05 22.0 7.4 8.6e-05 22.0 7.4 7.6 3 2 4 8 8 8 2 Growth-arrest specific micro-tubule binding VPS11_C PF12451.8 CCC70262.1 - 1.3 9.3 8.8 22 5.4 2.5 4.1 2 0 0 2 2 2 0 Vacuolar protein sorting protein 11 C terminal FAD_binding_1 PF00667.20 CCC70263.1 - 2.8e-68 229.8 0.0 5.6e-68 228.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 CCC70263.1 - 3.7e-08 34.0 0.0 2.3e-07 31.4 0.0 2.4 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Lum_binding PF00677.17 CCC70264.1 - 3.3e-45 152.0 2.8 3.8e-22 78.1 0.4 2.2 2 0 0 2 2 2 2 Lumazine binding domain Spore_GerAC PF05504.11 CCC70264.1 - 0.1 12.8 2.3 0.37 11.0 1.7 1.9 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal Cut8 PF08559.10 CCC70265.1 - 1.6e-70 237.4 8.4 1.6e-70 237.4 8.4 1.6 2 0 0 2 2 2 1 Cut8, nuclear proteasome tether protein DUF3169 PF11368.8 CCC70266.1 - 0.064 12.8 0.0 0.076 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) LMBR1 PF04791.16 CCC70267.1 - 0.0075 15.2 5.7 0.012 14.5 5.7 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein NOA36 PF06524.12 CCC70267.1 - 3 7.1 10.1 5.4 6.2 10.1 1.4 1 0 0 1 1 1 0 NOA36 protein Sedlin_N PF04628.13 CCC70268.1 - 4.1e-49 166.0 0.0 5.4e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 CCC70268.1 - 9.2e-05 22.4 0.5 0.0031 17.5 0.1 2.7 2 1 1 3 3 3 1 Sybindin-like family Med22 PF06179.12 CCC70269.1 - 1.8e-25 89.2 8.9 2.1e-25 89.0 8.9 1.0 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex V-set_2 PF15910.5 CCC70269.1 - 0.02 15.0 0.1 0.026 14.6 0.1 1.3 1 0 0 1 1 1 0 ICOS V-set domain GCIP PF13324.6 CCC70269.1 - 0.033 13.8 4.9 0.046 13.3 4.9 1.3 1 1 0 1 1 1 0 Grap2 and cyclin-D-interacting Ribosomal_S5 PF00333.20 CCC70270.1 - 1.5e-23 82.5 0.1 2.3e-23 82.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 CCC70270.1 - 2.7e-22 78.0 0.0 8.9e-22 76.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain HMG_box PF00505.19 CCC70271.1 - 3.8e-13 49.6 9.1 1.8e-12 47.4 9.1 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCC70271.1 - 0.00042 20.8 3.4 0.001 19.6 3.4 1.6 1 1 0 1 1 1 1 HMG-box domain DUF3724 PF12521.8 CCC70271.1 - 0.31 11.0 2.3 1.3 9.1 2.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) EB1 PF03271.17 CCC70273.1 - 4.9e-16 58.7 2.0 1.4e-15 57.3 2.0 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.31 CCC70273.1 - 4.6e-05 23.6 2.8 6.1e-05 23.2 0.5 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain zf-C4H2 PF10146.9 CCC70273.1 - 0.0082 16.5 3.6 0.016 15.5 3.6 1.4 1 0 0 1 1 1 1 Zinc finger-containing protein Pro_isomerase PF00160.21 CCC70273.1 - 0.085 13.1 0.2 0.39 11.0 0.1 2.0 2 1 0 2 2 2 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AMP-binding PF00501.28 CCC70274.1 - 1.3e-70 238.2 0.0 1.6e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Amino_oxidase PF01593.24 CCC70275.1 - 5.9e-10 39.0 0.0 6.4e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 CCC70275.1 - 1.9e-07 31.2 0.0 4.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 CCC70275.1 - 0.00027 21.4 0.8 0.089 13.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCC70275.1 - 0.0068 15.7 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.6 CCC70275.1 - 0.017 15.1 0.1 0.15 12.1 0.0 2.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.24 CCC70275.1 - 0.021 14.4 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CCC70275.1 - 0.052 12.8 0.0 0.16 11.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HA2 PF04408.23 CCC70276.1 - 4.7e-24 84.7 0.6 1.7e-23 82.9 0.0 2.3 3 0 0 3 3 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCC70276.1 - 1.6e-16 60.4 0.0 3.4e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CCC70276.1 - 2.4e-13 50.4 0.0 1.2e-12 48.2 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.23 CCC70276.1 - 6.4e-10 39.2 1.0 6.4e-10 39.2 1.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain DEAD PF00270.29 CCC70276.1 - 4.8e-06 26.5 0.2 1.3e-05 25.1 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCC70276.1 - 1e-05 25.8 0.0 3.4e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain PWI PF01480.17 CCC70276.1 - 0.0026 18.1 1.0 2.3 8.6 0.1 2.9 2 0 0 2 2 2 2 PWI domain T2SSE PF00437.20 CCC70276.1 - 0.0026 16.9 0.0 0.0092 15.1 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.27 CCC70276.1 - 0.011 16.3 7.1 0.42 11.1 0.1 3.7 3 1 0 4 4 4 0 ABC transporter AAA_30 PF13604.6 CCC70276.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 CCC70276.1 - 0.022 14.4 0.0 0.054 13.1 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 CCC70276.1 - 0.033 14.2 1.0 0.62 10.1 0.4 3.1 2 1 0 2 2 1 0 AAA domain Phage_TAC_12 PF12363.8 CCC70276.1 - 0.034 14.6 0.4 0.16 12.4 0.4 2.3 1 0 0 1 1 1 0 Phage tail assembly chaperone protein, TAC HIP1_clath_bdg PF16515.5 CCC70276.1 - 0.096 13.3 1.4 0.36 11.5 1.4 2.0 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AAA_24 PF13479.6 CCC70276.1 - 0.097 12.4 0.8 2.7 7.7 0.1 2.7 1 1 1 2 2 2 0 AAA domain DNA_pol3_gamma3 PF12169.8 CCC70276.1 - 0.12 12.3 0.0 0.36 10.7 0.0 1.8 1 1 1 2 2 2 0 DNA polymerase III subunits gamma and tau domain III AAA_16 PF13191.6 CCC70276.1 - 0.15 12.5 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 CCC70276.1 - 0.16 12.3 0.1 0.43 10.9 0.1 1.7 1 0 0 1 1 1 0 AAA domain Wbp11 PF09429.10 CCC70276.1 - 1.1 9.8 8.4 6.2 7.3 8.4 2.4 1 0 0 1 1 1 0 WW domain binding protein 11 Proteasome PF00227.26 CCC70277.1 - 2.9e-42 144.3 0.0 3.3e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit HIM1 PF08732.10 CCC70278.1 - 5.7e-10 39.0 0.0 1.4e-08 34.4 0.0 2.1 1 1 1 2 2 2 1 HIM1 NAD_binding_10 PF13460.6 CCC70278.1 - 0.00031 20.7 0.0 0.00046 20.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CCC70278.1 - 0.071 12.6 0.0 0.36 10.2 0.0 2.2 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HIM1 PF08732.10 CCC70279.1 - 4.7e-08 32.7 0.0 3.3e-07 30.0 0.0 1.9 1 1 1 2 2 2 1 HIM1 NAD_binding_10 PF13460.6 CCC70279.1 - 0.00032 20.6 0.0 0.0005 20.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 CCC70279.1 - 0.0032 17.0 0.0 0.0041 16.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 CCC70279.1 - 0.03 13.9 0.0 0.049 13.2 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family SRP1_TIP1 PF00660.17 CCC70280.1 - 2.6e-29 101.2 0.1 6e-29 100.0 0.1 1.6 1 0 0 1 1 1 1 Seripauperin and TIP1 family PIR PF00399.19 CCC70280.1 - 1.9e-06 27.2 9.6 1.9e-06 27.2 9.6 3.2 2 0 0 2 2 2 1 Yeast PIR protein repeat Utp14 PF04615.13 CCC70280.1 - 0.092 11.3 1.9 0.1 11.2 1.9 1.0 1 0 0 1 1 1 0 Utp14 protein RNA_pol_Rpc4 PF05132.14 CCC70280.1 - 0.26 11.7 3.1 0.39 11.1 3.1 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Macoilin PF09726.9 CCC70280.1 - 4.4 5.7 13.4 5.8 5.4 13.4 1.1 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 CCC70280.1 - 6.2 6.7 7.9 8.4 6.3 7.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRP1_TIP1 PF00660.17 CCC70281.1 - 5.3e-71 234.9 16.4 2.8e-23 81.8 0.2 4.6 4 0 0 4 4 4 3 Seripauperin and TIP1 family DUF257 PF03192.13 CCC70281.1 - 0.00053 19.9 1.2 11 5.8 0.0 3.3 3 0 0 3 3 3 3 Pyrococcus protein of unknown function, DUF257 DUF5331 PF17265.2 CCC70281.1 - 0.0036 17.0 0.0 34 4.2 0.0 3.5 3 0 0 3 3 3 3 Family of unknown function (DUF5331) HbrB PF08539.11 CCC70281.1 - 0.011 15.7 15.7 1.3 8.9 1.0 3.9 3 1 0 3 3 3 0 HbrB-like WSC PF01822.19 CCC70282.1 - 3.9e-11 43.0 13.1 3.9e-11 43.0 13.1 2.4 3 0 0 3 3 3 1 WSC domain DUF5305 PF17231.2 CCC70282.1 - 0.00041 19.8 2.1 0.00041 19.8 2.1 1.9 1 1 1 2 2 2 1 Family of unknown function (DUF5305) Amnionless PF14828.6 CCC70282.1 - 0.003 16.4 0.3 0.0045 15.9 0.3 1.3 1 0 0 1 1 1 1 Amnionless DUF456 PF04306.13 CCC70282.1 - 0.009 16.3 0.1 0.015 15.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.6 CCC70282.1 - 0.042 13.8 5.7 0.08 13.0 5.7 1.4 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_YMGG PF13441.6 CCC70282.1 - 0.066 13.0 3.1 0.12 12.2 3.1 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper MscL PF01741.18 CCC70282.1 - 0.087 13.1 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL TMEM154 PF15102.6 CCC70282.1 - 9.2 6.2 17.9 1.1 9.2 0.6 2.4 1 1 1 2 2 2 0 TMEM154 protein family DUF2408 PF10303.9 CCC70283.1 - 4.4e-65 218.3 28.8 7e-46 156.1 5.2 5.2 2 2 3 5 5 5 4 Protein of unknown function (DUF2408) MLD PF11647.8 CCC70283.1 - 0.014 15.7 1.8 0.24 11.7 0.4 3.6 3 1 0 3 3 3 0 Membrane Localization Domain PLAC9 PF15205.6 CCC70283.1 - 0.056 13.8 0.3 55 4.3 0.0 3.5 2 1 1 3 3 3 0 Placenta-specific protein 9 FAA_hydro_N_2 PF18288.1 CCC70283.1 - 0.066 13.6 1.5 7.7 7.0 0.0 3.6 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 MtrG PF04210.13 CCC70283.1 - 0.23 11.3 0.3 21 5.1 0.0 3.0 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Exonuc_VII_L PF02601.15 CCC70283.1 - 0.97 8.9 9.2 4.1 6.9 9.3 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit Osmo_CC PF08946.10 CCC70283.1 - 1.7 9.0 0.0 1.7 9.0 0.0 4.1 4 0 0 4 4 4 0 Osmosensory transporter coiled coil Adap_comp_sub PF00928.21 CCC70284.1 - 1.4e-92 309.8 4.0 1.9e-92 309.4 4.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CCC70284.1 - 2.5e-05 24.3 1.7 5.5e-05 23.1 1.0 1.9 1 1 1 2 2 2 1 Clathrin adaptor complex small chain ALC PF17527.2 CCC70284.1 - 0.029 14.0 0.1 0.058 13.0 0.1 1.5 1 0 0 1 1 1 0 Phage ALC protein TPP1 PF10341.9 CCC70285.1 - 7.1e-29 100.0 0.1 9.6e-29 99.6 0.1 1.2 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD ETF_QO PF05187.13 CCC70286.1 - 3.8e-43 145.8 0.4 6.3e-43 145.2 0.4 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 CCC70286.1 - 1.5e-08 34.6 0.4 0.00047 19.8 0.6 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCC70286.1 - 3.2e-08 33.7 0.0 9.6e-08 32.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 CCC70286.1 - 5.6e-08 32.4 0.0 2.1e-05 23.9 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCC70286.1 - 5.3e-07 29.1 0.0 5.3e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 CCC70286.1 - 1.4e-06 27.6 0.2 0.00055 19.1 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 CCC70286.1 - 2.8e-05 23.0 0.2 0.00051 18.9 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 CCC70286.1 - 0.00023 20.5 0.1 0.00042 19.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 CCC70286.1 - 0.0003 20.2 0.0 0.00044 19.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CCC70286.1 - 0.00045 20.7 0.3 0.62 10.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 CCC70286.1 - 0.00076 19.5 0.1 0.0013 18.7 0.1 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.7 CCC70286.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 CCC70286.1 - 0.014 14.5 0.2 0.02 13.9 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Fer4_7 PF12838.7 CCC70286.1 - 0.015 15.8 1.0 0.034 14.8 1.0 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain K_oxygenase PF13434.6 CCC70286.1 - 0.023 13.9 0.0 0.038 13.1 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GMC_oxred_N PF00732.19 CCC70286.1 - 0.046 13.1 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Trp_halogenase PF04820.14 CCC70286.1 - 0.06 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase MAF_flag10 PF01973.18 CCC70286.1 - 0.11 12.1 0.0 6.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF115 Fer4_2 PF12797.7 CCC70286.1 - 0.2 11.8 0.7 0.51 10.6 0.7 1.6 1 0 0 1 1 1 0 4Fe-4S binding domain tRNA_synt_1c_R1 PF04558.15 CCC70287.1 - 0.056 13.5 0.2 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Cyclin_N PF00134.23 CCC70288.1 - 3.6e-27 94.6 2.8 6.2e-27 93.9 2.1 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain SOG2 PF10428.9 CCC70290.1 - 7.6e-157 523.6 24.4 7.6e-157 523.6 24.4 3.2 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_8 PF13855.6 CCC70290.1 - 2.8e-15 55.8 14.1 1.2e-09 37.8 5.2 3.2 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 CCC70290.1 - 2e-11 43.9 22.6 5.9e-08 32.9 1.1 5.0 3 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 CCC70290.1 - 0.0012 18.4 4.5 0.0012 18.4 4.5 2.3 2 0 0 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 CCC70290.1 - 0.0034 17.3 7.5 1.8 8.8 0.0 5.7 5 0 0 5 5 5 1 Leucine Rich repeat SUIM_assoc PF16619.5 CCC70290.1 - 0.0037 17.3 2.7 0.0037 17.3 2.7 3.3 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 PRD PF00874.20 CCC70290.1 - 0.034 14.4 3.6 0.13 12.6 1.7 2.7 2 0 0 2 2 2 0 PRD domain SpecificRecomb PF10136.9 CCC70290.1 - 0.51 8.6 6.9 0.051 11.9 0.3 2.0 2 0 0 2 2 2 0 Site-specific recombinase LRR_1 PF00560.33 CCC70290.1 - 1.1 10.1 30.0 1.9 9.3 0.2 7.6 8 0 0 8 8 8 0 Leucine Rich Repeat TFB6 PF17110.5 CCC70291.1 - 6e-37 127.0 0.0 2.6e-32 111.9 0.0 2.3 1 1 1 2 2 2 2 Subunit 11 of the general transcription factor TFIIH ADH_zinc_N PF00107.26 CCC70292.1 - 2.2e-11 43.8 0.1 3.7e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCC70292.1 - 9.2e-06 25.5 0.2 0.00026 20.8 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CCC70292.1 - 0.15 13.1 0.0 0.27 12.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Pkinase PF00069.25 CCC70293.1 - 2.4e-55 187.8 0.1 5.1e-55 186.7 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70293.1 - 7.9e-29 100.7 0.0 1.3e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 CCC70293.1 - 3.4e-15 56.1 0.3 2.8e-14 53.2 0.0 2.5 3 0 0 3 3 3 1 FHA domain Pkinase_fungal PF17667.1 CCC70293.1 - 6.6e-05 21.9 0.0 0.00011 21.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 CCC70293.1 - 0.0026 16.7 0.1 0.0049 15.9 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 CCC70293.1 - 0.009 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L20 PF00453.18 CCC70293.1 - 0.068 13.3 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L20 MNE1 PF13762.6 CCC70294.1 - 1.2e-16 61.1 10.4 2.2e-16 60.2 4.1 3.0 2 0 0 2 2 2 1 Mitochondrial splicing apparatus component F-box PF00646.33 CCC70294.1 - 0.092 12.7 0.3 0.25 11.3 0.3 1.7 1 0 0 1 1 1 0 F-box domain DUF4460 PF14687.6 CCC70294.1 - 0.59 10.2 3.7 6.6 6.8 0.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4460) PPIP5K2_N PF18086.1 CCC70295.1 - 0.2 11.8 2.0 0.78 9.9 0.1 3.0 3 0 0 3 3 3 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain AA_permease PF00324.21 CCC70296.1 - 4.5e-132 441.0 34.0 5.1e-132 440.9 34.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC70296.1 - 9.8e-26 90.5 37.5 1.2e-25 90.2 37.5 1.1 1 0 0 1 1 1 1 Amino acid permease DNApol_Exo PF18136.1 CCC70297.1 - 1.7e-101 339.1 0.0 2.5e-101 338.5 0.0 1.3 1 0 0 1 1 1 1 DNA mitochondrial polymerase exonuclease domain DNA_pol_A PF00476.20 CCC70297.1 - 2.2e-54 185.0 0.0 3.6e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A CorA PF01544.18 CCC70298.1 - 5e-08 32.6 2.9 7.4e-08 32.1 2.9 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DNAJ_related PF12339.8 CCC70298.1 - 0.037 14.2 2.4 0.066 13.4 2.4 1.4 1 0 0 1 1 1 0 DNA-J related protein tRNA-synt_2c PF01411.19 CCC70299.1 - 3.7e-229 761.8 0.8 5.2e-229 761.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 CCC70299.1 - 5.6e-18 64.8 0.4 1.5e-17 63.4 0.4 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.19 CCC70299.1 - 3.6e-14 53.3 4.7 8.1e-14 52.2 4.7 1.6 1 0 0 1 1 1 1 DHHA1 domain Glyco_transf_24 PF18404.1 CCC70300.1 - 8.3e-33 113.9 0.5 1.7e-32 112.9 0.5 1.5 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 CCC70300.1 - 5.4e-17 62.6 6.8 3.4e-13 50.1 0.3 4.8 3 1 2 5 5 5 2 Thioredoxin-like domain Thioredoxin_13 PF18401.1 CCC70300.1 - 1.3e-10 41.4 2.0 6.3e-10 39.1 1.1 2.6 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 CCC70300.1 - 5.7e-06 26.3 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 CCC70300.1 - 0.0053 16.9 0.0 0.014 15.5 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Bcl-2_3 PF15286.6 CCC70300.1 - 0.077 13.7 0.2 17 6.1 0.0 3.1 3 0 0 3 3 3 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like SSL_OB PF09199.10 CCC70300.1 - 0.1 12.9 1.1 0.36 11.2 0.2 2.4 2 0 0 2 2 2 0 Staphylococcal superantigen-like OB-fold domain Fungal_trans PF04082.18 CCC70301.1 - 9.2e-37 126.5 2.0 9.2e-37 126.5 2.0 2.7 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC70301.1 - 3.5e-09 36.6 10.4 5.9e-09 35.9 10.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIRM PF04433.17 CCC70302.1 - 5.2e-09 36.3 0.0 1.3e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain RPA43_OB PF17875.1 CCC70303.1 - 8.5e-32 110.4 0.1 8.5e-32 110.4 0.1 1.8 2 0 0 2 2 2 1 RPA43 OB domain in RNA Pol I SHS2_Rpb7-N PF03876.17 CCC70303.1 - 5.4e-12 45.9 0.0 1.4e-11 44.6 0.0 1.7 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GTP_EFTU PF00009.27 CCC70304.1 - 2.7e-34 118.4 0.0 2.7e-34 118.4 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 CCC70304.1 - 3.2e-21 75.4 0.0 1.1e-20 73.7 0.0 2.0 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 CCC70304.1 - 4.1e-12 46.3 6.4 2.3e-09 37.5 0.0 3.7 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCC70304.1 - 3.6e-06 27.0 0.0 3.6e-06 27.0 0.0 3.4 4 0 0 4 4 4 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CCC70304.1 - 1.2e-05 25.1 0.1 3.9e-05 23.5 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Roc PF08477.13 CCC70304.1 - 0.0007 19.8 0.0 0.0007 19.8 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CCC70304.1 - 0.018 14.6 0.0 0.087 12.3 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Actin_micro PF17003.5 CCC70305.1 - 0.008 15.4 1.6 0.012 14.9 1.3 1.4 1 1 0 1 1 1 1 Putative actin-like family DUF3830 PF12903.7 CCC70305.1 - 0.028 14.1 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3830) HLH PF00010.26 CCC70306.1 - 3.4e-18 65.3 0.0 1.3e-17 63.5 0.0 2.0 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain Porphobil_deam PF01379.20 CCC70306.1 - 0.015 14.8 0.1 0.028 13.9 0.1 1.5 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain IMS PF00817.20 CCC70307.1 - 1.2e-28 100.0 0.1 2.2e-28 99.1 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family BRCT_2 PF16589.5 CCC70307.1 - 1.4e-12 47.8 0.0 5.4e-12 46.0 0.0 2.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 CCC70307.1 - 1.7e-10 41.1 3.7 1.9e-10 41.0 0.1 2.8 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain IMS_C PF11799.8 CCC70307.1 - 9.9e-10 39.2 0.0 3.2e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain REV1_C PF16727.5 CCC70307.1 - 1.5e-07 31.7 0.0 3.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 DNA repair protein REV1 C-terminal domain PTCB-BRCT PF12738.7 CCC70307.1 - 1.2e-05 25.1 0.1 0.0001 22.2 0.0 2.4 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 CCC70307.1 - 3.3e-05 24.1 0.0 8e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain Terminase_2 PF03592.16 CCC70307.1 - 0.061 13.8 0.5 0.16 12.4 0.5 1.6 1 0 0 1 1 1 0 Terminase small subunit BRCT_3 PF18428.1 CCC70307.1 - 0.15 12.1 0.5 0.62 10.2 0.0 2.3 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain PK PF00224.21 CCC70308.1 - 1.1e-163 544.2 0.7 1.4e-163 543.8 0.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 CCC70308.1 - 6.8e-32 110.1 0.0 1.4e-31 109.1 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 CCC70308.1 - 0.00012 21.3 0.1 0.00037 19.7 0.1 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family ATP-synt_ab PF00006.25 CCC70309.1 - 5.2e-72 242.0 0.0 7.3e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 CCC70309.1 - 3e-47 160.1 0.9 5.1e-47 159.3 0.9 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 CCC70309.1 - 4.2e-16 59.2 1.4 1.2e-15 57.8 1.4 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Tex_N PF09371.10 CCC70309.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 Tex-like protein N-terminal domain Cnd2 PF05786.14 CCC70310.1 - 8.8e-141 471.1 54.9 3.9e-139 465.6 54.9 2.0 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 CCC70310.1 - 0.00025 21.2 0.0 0.00025 21.2 0.0 3.5 4 0 0 4 4 4 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal 4HBT PF03061.22 CCC70311.1 - 0.00015 22.0 0.0 0.00026 21.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily FAIM1 PF06905.13 CCC70311.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Fas apoptotic inhibitory molecule (FAIM1) Rox3 PF08633.10 CCC70312.1 - 2.9e-37 128.9 0.8 3.5e-37 128.7 0.8 1.1 1 0 0 1 1 1 1 Rox3 mediator complex subunit Ribosomal_L32e PF01655.18 CCC70313.1 - 4.2e-46 155.8 1.7 4.9e-46 155.6 1.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Aa_trans PF01490.18 CCC70314.1 - 6.3e-109 364.4 19.0 7.7e-109 364.1 19.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 CCC70314.1 - 3.1e-08 33.1 17.9 6.4e-08 32.0 17.9 1.6 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family DUF4044 PF13253.6 CCC70314.1 - 0.17 11.4 0.1 0.17 11.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4044) PI3_PI4_kinase PF00454.27 CCC70315.1 - 3.8e-58 197.3 0.0 7.7e-58 196.2 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.8 CCC70315.1 - 4.8e-26 91.7 4.2 3.3e-25 89.0 4.2 2.7 1 0 0 1 1 1 1 Telomere-length maintenance and DNA damage repair FATC PF02260.20 CCC70315.1 - 1e-11 44.4 0.0 2.4e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 FATC domain PARP_reg PF02877.14 CCC70315.1 - 0.1 12.7 1.3 0.35 11.0 0.8 2.2 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Ribosomal_L14 PF00238.19 CCC70316.1 - 9.8e-33 112.8 0.0 1.2e-32 112.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e NT-C2 PF10358.9 CCC70317.1 - 1.1e-39 135.5 8.0 1.1e-39 135.5 8.0 2.2 2 1 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins Flg_new PF09479.10 CCC70317.1 - 0.073 13.3 1.9 0.14 12.4 0.1 2.5 2 0 0 2 2 2 0 Listeria-Bacteroides repeat domain (List_Bact_rpt) PH PF00169.29 CCC70318.1 - 2e-16 60.4 0.1 9.7e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.17 CCC70318.1 - 1.3e-12 47.6 0.0 3e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.28 CCC70318.1 - 3.9e-09 36.0 0.0 8.5e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCC70318.1 - 6.5e-09 35.5 0.0 1.5e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_1 PF00536.30 CCC70318.1 - 5e-07 30.1 0.0 1.2e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.17 CCC70318.1 - 0.00045 19.8 0.0 0.0012 18.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.6 CCC70318.1 - 0.00075 19.7 0.0 0.0079 16.5 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_Ste50p PF09235.10 CCC70318.1 - 0.041 14.1 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PH_11 PF15413.6 CCC70318.1 - 0.24 11.8 0.1 0.24 11.8 0.1 3.9 3 1 0 3 3 3 0 Pleckstrin homology domain TPR_1 PF00515.28 CCC70319.1 - 1.1e-35 120.0 14.2 1.8e-09 37.0 0.2 8.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.17 CCC70319.1 - 4.6e-33 110.7 14.3 4.1e-07 29.6 0.1 8.7 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 CCC70319.1 - 7.3e-28 94.4 15.9 0.00011 22.2 0.2 8.6 9 0 0 9 9 8 6 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC70319.1 - 1.1e-23 83.3 25.2 9.3e-13 48.2 1.0 5.2 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 CCC70319.1 - 6.9e-20 70.5 9.2 0.00043 19.9 0.0 7.5 5 1 3 8 8 8 4 TPR repeat TPR_12 PF13424.6 CCC70319.1 - 6.9e-16 58.3 8.4 6.8e-05 23.1 0.1 6.6 6 2 0 6 6 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 CCC70319.1 - 2e-15 56.2 0.4 0.022 15.6 0.1 6.4 3 1 4 7 7 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 CCC70319.1 - 1.1e-13 51.6 0.2 8.7e-05 23.1 0.0 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 CCC70319.1 - 9.1e-13 47.3 1.5 1.3 9.3 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCC70319.1 - 1.3e-12 48.1 1.3 0.00056 20.4 0.0 5.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 CCC70319.1 - 1.4e-12 47.4 19.3 0.0028 18.2 0.0 9.1 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.6 CCC70319.1 - 5.2e-11 42.1 8.4 1.2 9.7 0.0 8.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_15 PF13429.6 CCC70319.1 - 1.4e-07 31.1 0.2 0.0023 17.2 0.0 3.6 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCC70319.1 - 5.5e-07 29.6 0.0 0.0006 19.9 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 CCC70319.1 - 0.0027 17.4 1.4 0.9 9.2 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat-like domain SRP_TPR_like PF17004.5 CCC70319.1 - 0.007 16.4 1.2 0.007 16.4 1.2 3.1 3 1 0 3 3 2 1 Putative TPR-like repeat ANAPC5 PF12862.7 CCC70319.1 - 0.0087 16.1 4.3 0.074 13.1 1.0 4.0 4 1 0 4 4 4 1 Anaphase-promoting complex subunit 5 TPR_10 PF13374.6 CCC70319.1 - 0.012 15.4 3.9 41 4.2 0.0 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCC70319.1 - 0.014 15.4 9.9 2.7 8.1 0.1 5.7 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 CCC70319.1 - 0.032 14.7 0.3 9.7 6.6 0.0 2.7 1 1 1 2 2 2 0 Bacterial transcriptional activator domain SNAP PF14938.6 CCC70319.1 - 0.071 12.5 8.2 10 5.5 8.0 3.5 1 1 0 1 1 1 0 Soluble NSF attachment protein, SNAP MIT PF04212.18 CCC70319.1 - 0.1 12.7 8.4 3.3 7.9 0.1 5.2 6 2 1 7 7 7 0 MIT (microtubule interacting and transport) domain PAP2_3 PF14378.6 CCC70320.1 - 1.3e-24 86.9 10.0 1.3e-24 86.9 10.0 2.1 2 0 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 CCC70320.1 - 1.9e-11 43.9 6.0 1.9e-11 43.9 6.0 2.5 2 1 0 2 2 2 1 PAP2 superfamily ALG3 PF05208.13 CCC70321.1 - 2.8e-129 431.7 22.7 3.3e-129 431.4 22.7 1.0 1 0 0 1 1 1 1 ALG3 protein LisH PF08513.11 CCC70322.1 - 2.4e-05 24.1 0.1 5.2e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 LisH DUF5349 PF17298.2 CCC70323.1 - 3.5e-38 132.3 97.2 2.1e-22 80.4 28.7 3.0 1 1 1 2 2 2 2 Family of unknown function (DUF5349) GatB_N PF02934.15 CCC70324.1 - 4.8e-96 321.3 0.2 6.6e-96 320.9 0.2 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 CCC70324.1 - 2.9e-30 105.1 0.9 5.2e-30 104.3 0.9 1.4 1 0 0 1 1 1 1 GatB domain Nucleoporin_N PF08801.11 CCC70325.1 - 8.8e-131 436.6 7.6 9.8e-131 436.5 6.6 1.6 2 0 0 2 2 2 1 Nup133 N terminal like Nucleoporin_C PF03177.14 CCC70325.1 - 2.6e-126 422.8 9.4 5.6e-125 418.4 9.4 2.1 1 1 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Atg8 PF02991.16 CCC70326.1 - 2.2e-49 166.0 0.1 3.1e-49 165.5 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 CCC70326.1 - 3e-05 24.3 0.0 4.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 tRNA-synt_1 PF00133.22 CCC70327.1 - 8.8e-244 810.3 1.3 2.3e-243 808.9 0.3 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 CCC70327.1 - 2.1e-24 86.2 0.1 8e-24 84.3 0.0 2.0 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 CCC70327.1 - 3.3e-15 55.7 3.1 1.7e-05 23.8 0.4 4.1 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 CCC70327.1 - 0.00053 19.4 0.0 0.0021 17.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain DUF1435 PF07256.12 CCC70327.1 - 0.18 11.9 0.0 0.74 10.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) HSP70 PF00012.20 CCC70328.1 - 2.8e-256 851.5 9.0 3.2e-256 851.3 9.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCC70328.1 - 2.1e-16 59.7 0.1 2.5e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 CCC70328.1 - 0.00028 20.7 0.0 0.00074 19.3 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 CCC70328.1 - 0.013 14.5 0.4 0.52 9.3 0.2 2.2 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 CCC70328.1 - 0.027 14.0 0.1 4.2 6.8 0.0 2.5 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 CCC70328.1 - 0.079 12.2 0.1 0.23 10.7 0.1 1.9 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Golgin_A5 PF09787.9 CCC70328.1 - 0.084 12.3 8.0 0.18 11.2 4.9 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 SWI-SNF_Ssr4 PF08549.10 CCC70328.1 - 1.1 7.8 6.1 1.3 7.6 0.1 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Ribosomal_S8e PF01201.22 CCC70329.1 - 1.3e-55 187.3 2.5 1.5e-55 187.1 2.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e UQ_con PF00179.26 CCC70330.1 - 1.1e-21 76.9 0.0 1.7e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 CCC70330.1 - 1.2 9.5 4.2 0.28 11.5 0.2 1.9 2 1 0 2 2 2 0 RWD domain UCH PF00443.29 CCC70331.1 - 3.6e-61 206.9 8.4 3.6e-61 206.9 8.4 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCC70331.1 - 4.3e-22 79.1 10.7 6.8e-19 68.6 2.0 2.6 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 CCC70331.1 - 0.14 11.6 5.3 0.35 10.3 3.2 2.6 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Fungal_trans PF04082.18 CCC70332.1 - 1.3e-21 76.8 2.4 3e-21 75.7 2.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC70332.1 - 1.3e-08 34.8 11.5 2.2e-08 34.1 11.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.21 CCC70333.1 - 2.1e-31 108.4 0.0 2.9e-31 108.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 CCC70333.1 - 4.5e-11 42.4 0.0 7.5e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 CCC70333.1 - 7.6e-10 38.7 0.0 1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin Pribosyl_synth PF14572.6 CCC70333.1 - 0.065 13.3 0.1 0.094 12.7 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain Kinesin PF00225.23 CCC70334.1 - 1.4e-107 359.5 1.1 1.4e-107 359.5 1.1 2.6 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CCC70334.1 - 8.2e-25 87.5 0.0 8.2e-25 87.5 0.0 4.1 4 2 0 5 5 5 1 Microtubule binding DUF1512 PF07431.12 CCC70334.1 - 4.2 6.3 10.5 0.24 10.3 0.7 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF1512) RNA_helicase PF00910.22 CCC70334.1 - 4.4 7.7 6.6 39 4.7 0.3 4.4 4 0 0 4 4 4 0 RNA helicase Sel1 PF08238.12 CCC70335.1 - 2.9e-42 142.1 19.3 3.5e-07 30.7 0.1 7.8 7 0 0 7 7 7 7 Sel1 repeat Sec7 PF01369.20 CCC70336.1 - 1e-14 54.6 0.5 2.2e-14 53.6 0.1 1.7 2 0 0 2 2 2 1 Sec7 domain Cmc1 PF08583.10 CCC70337.1 - 8.8e-18 64.1 5.5 1.4e-17 63.4 5.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.13 CCC70337.1 - 0.026 14.6 1.8 1.5 9.1 0.2 2.3 2 0 0 2 2 2 0 CHCH domain DUF4322 PF14210.6 CCC70337.1 - 0.026 14.4 0.4 0.045 13.6 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4322) NDUF_B7 PF05676.13 CCC70337.1 - 0.22 11.2 3.9 0.56 10.0 3.9 1.7 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Antimicrobial23 PF16048.5 CCC70338.1 - 0.31 10.8 1.8 0.58 9.9 1.8 1.4 1 0 0 1 1 1 0 Frog antimicrobial peptide SEP PF08059.13 CCC70339.1 - 7.8e-23 80.8 0.2 2e-22 79.5 0.2 1.8 1 0 0 1 1 1 1 SEP domain UBX PF00789.20 CCC70339.1 - 1.5e-17 63.6 0.1 2.7e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CCC70339.1 - 3.9e-13 49.0 0.5 7e-13 48.2 0.5 1.4 1 0 0 1 1 1 1 UBA-like domain TAP_C PF03943.13 CCC70339.1 - 0.055 13.1 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 TAP C-terminal domain Spindle_Spc25 PF08234.12 CCC70339.1 - 0.62 10.3 2.9 0.84 9.9 0.2 2.7 3 1 1 4 4 4 0 Chromosome segregation protein Spc25 PTH2 PF01981.16 CCC70340.1 - 7e-46 155.3 0.2 7e-46 155.3 0.2 1.5 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 T2SSM PF04612.12 CCC70340.1 - 0.012 15.6 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Hen1_Lam_C PF18441.1 CCC70340.1 - 0.016 15.0 0.1 0.024 14.5 0.1 1.3 1 0 0 1 1 1 0 Hen1 La-motif C-terminal domain DNA_pol_phi PF04931.13 CCC70340.1 - 0.13 10.4 6.1 0.15 10.1 6.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF2457 PF10446.9 CCC70340.1 - 4.2 6.4 10.4 5.6 6.0 10.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DYW_deaminase PF14432.6 CCC70341.1 - 0.066 13.1 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 DYW family of nucleic acid deaminases PP2C PF00481.21 CCC70342.1 - 7.3e-79 265.0 0.0 9.6e-79 264.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C TatD_DNase PF01026.21 CCC70343.1 - 9.9e-37 126.7 0.0 1.2e-36 126.4 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Myb_DNA-binding PF00249.31 CCC70344.1 - 2.1e-11 43.8 4.2 2.5e-09 37.2 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCC70344.1 - 6.3e-08 32.8 8.4 6.9e-08 32.6 0.5 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain SelP_N PF04592.14 CCC70344.1 - 0.21 10.9 8.8 0.48 9.8 8.8 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MOZ_SAS PF01853.18 CCC70345.1 - 4.4e-73 244.7 0.4 7.4e-73 244.0 0.4 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CCC70345.1 - 3.4e-17 61.8 5.0 8.6e-17 60.5 5.0 1.7 1 0 0 1 1 1 1 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CCC70345.1 - 0.042 14.3 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DnaB_2 PF07261.11 CCC70345.1 - 0.11 12.2 0.5 1.1 9.1 0.2 2.6 2 0 0 2 2 2 0 Replication initiation and membrane attachment Sec61_beta PF03911.16 CCC70346.1 - 7e-16 58.0 0.7 8.7e-16 57.7 0.7 1.1 1 0 0 1 1 1 1 Sec61beta family Med21 PF11221.8 CCC70347.1 - 4.5 7.5 11.8 0.95 9.7 0.7 2.9 3 0 0 3 3 3 0 Subunit 21 of Mediator complex ATG16 PF08614.11 CCC70347.1 - 5.1 7.3 14.2 0.94 9.7 8.9 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) MMR1 PF08505.10 CCC70348.1 - 9.6e-24 85.1 30.7 9.6e-24 85.1 30.7 3.9 2 2 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein GerA PF03323.13 CCC70348.1 - 4.5 5.6 4.6 6.8 5.0 4.6 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Peroxin-13_N PF04088.13 CCC70349.1 - 2.6e-53 180.2 0.5 3.8e-53 179.7 0.5 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.6 CCC70349.1 - 3.6e-07 30.0 0.0 5.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 CCC70349.1 - 5.4e-07 29.1 0.0 9.7e-07 28.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.11 CCC70349.1 - 0.0043 17.3 0.0 0.0089 16.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain Pex2_Pex12 PF04757.14 CCC70349.1 - 0.014 15.0 0.2 0.099 12.2 0.2 2.0 1 1 1 2 2 2 0 Pex2 / Pex12 amino terminal region MSL1_dimer PF16801.5 CCC70349.1 - 0.21 11.4 1.6 0.44 10.3 1.6 1.5 1 0 0 1 1 1 0 Dimerisation domain of Male-specific-Lethal 1 Keratin_2_head PF16208.5 CCC70349.1 - 0.41 10.8 19.5 0.69 10.0 19.5 1.3 1 0 0 1 1 1 0 Keratin type II head eIF3_subunit PF08597.10 CCC70350.1 - 1.4e-49 169.2 19.1 8e-49 166.7 19.1 1.8 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit PRELI PF04707.14 CCC70351.1 - 5.6e-45 153.0 0.5 6.8e-45 152.7 0.5 1.0 1 0 0 1 1 1 1 PRELI-like family NMT_C PF02799.15 CCC70353.1 - 1.2e-78 263.4 0.2 2e-78 262.7 0.2 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 CCC70353.1 - 4.8e-75 250.8 0.1 4.8e-75 250.8 0.1 2.3 3 0 0 3 3 3 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 CCC70353.1 - 0.00071 19.8 0.0 0.0018 18.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 CCC70353.1 - 0.006 16.7 0.0 0.038 14.1 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain WD40 PF00400.32 CCC70354.1 - 5.1e-09 36.6 9.0 0.00066 20.4 0.5 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat Nup160 PF11715.8 CCC70354.1 - 1.9e-06 26.8 2.6 0.00014 20.6 0.5 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.6 CCC70354.1 - 0.0033 17.8 0.3 0.37 11.4 0.0 3.6 4 1 1 5 5 5 1 PQQ-like domain SUKH_6 PF14568.6 CCC70354.1 - 0.029 14.8 0.1 0.029 14.8 0.1 2.8 4 1 0 4 4 4 0 SMI1-KNR4 cell-wall POC1 PF10450.9 CCC70355.1 - 5.7e-91 304.3 1.6 6.4e-91 304.1 1.6 1.0 1 0 0 1 1 1 1 POC1 chaperone Prefoldin_2 PF01920.20 CCC70356.1 - 1e-24 86.5 12.0 1.2e-24 86.3 12.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit Sec2p PF06428.11 CCC70356.1 - 0.003 17.5 8.5 0.064 13.2 1.2 2.1 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p Prefoldin_3 PF13758.6 CCC70356.1 - 0.0085 16.1 4.6 0.011 15.7 4.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit MIP-T3_C PF17749.1 CCC70356.1 - 0.0093 15.9 4.4 0.0093 15.9 4.4 1.9 1 1 0 2 2 2 1 Microtubule-binding protein MIP-T3 C-terminal region Prefoldin PF02996.17 CCC70356.1 - 0.048 13.6 8.4 0.24 11.3 8.4 1.9 1 1 0 1 1 1 0 Prefoldin subunit DUF883 PF05957.13 CCC70356.1 - 0.08 13.6 0.9 0.17 12.5 0.4 1.8 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Spc24 PF08286.11 CCC70356.1 - 0.088 13.1 9.5 0.73 10.1 0.4 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF4164 PF13747.6 CCC70356.1 - 0.091 13.1 5.9 0.23 11.8 1.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Uso1_p115_C PF04871.13 CCC70356.1 - 0.15 12.4 8.0 0.32 11.3 8.1 1.5 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region APG6_N PF17675.1 CCC70356.1 - 0.22 12.0 11.7 0.93 10.0 11.7 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region FapA PF03961.13 CCC70356.1 - 0.24 10.0 8.3 0.27 9.8 8.3 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A End3 PF12761.7 CCC70356.1 - 0.27 11.4 7.9 0.33 11.1 7.9 1.1 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Bcr-Abl_Oligo PF09036.10 CCC70356.1 - 0.35 10.9 6.5 0.46 10.5 1.8 2.2 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Mt_ATP-synt_D PF05873.12 CCC70356.1 - 0.36 10.7 8.9 0.32 10.8 5.0 1.9 1 1 1 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) DUF641 PF04859.12 CCC70356.1 - 0.5 10.7 9.8 2.7 8.3 4.7 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DMPK_coil PF08826.10 CCC70356.1 - 0.79 9.9 10.1 0.55 10.4 1.4 2.6 2 1 0 2 2 2 0 DMPK coiled coil domain like UPF0242 PF06785.11 CCC70356.1 - 1 9.4 13.4 2.6 8.1 13.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 CCC70356.1 - 1 9.5 8.1 1.7 8.9 8.1 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.22 CCC70356.1 - 1 9.6 10.8 0.79 10.0 6.1 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain OmpH PF03938.14 CCC70356.1 - 2.8 8.3 12.1 12 6.2 12.1 1.8 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) THOC7 PF05615.13 CCC70356.1 - 6.8 7.0 12.3 28 5.0 12.3 1.8 1 1 0 1 1 1 0 Tho complex subunit 7 COQ9 PF08511.11 CCC70357.1 - 2.3e-23 81.7 0.5 4.3e-23 80.9 0.5 1.4 1 0 0 1 1 1 1 COQ9 zf-Mss51 PF13824.6 CCC70358.1 - 9.6e-19 67.2 0.8 1.1e-17 63.9 0.4 2.3 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.11 CCC70358.1 - 0.027 14.2 0.4 0.061 13.1 0.4 1.6 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Heme_oxygenase PF01126.20 CCC70359.1 - 4.2e-13 49.5 1.0 2e-12 47.4 1.0 2.1 1 1 0 1 1 1 1 Heme oxygenase Ribosomal_S18 PF01084.20 CCC70360.1 - 3.4e-19 68.8 0.0 6.2e-19 68.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Linker_histone PF00538.19 CCC70360.1 - 0.22 11.9 4.1 0.82 10.1 0.2 2.5 2 1 1 3 3 3 0 linker histone H1 and H5 family Ofd1_CTDD PF10637.9 CCC70361.1 - 2.3e-83 279.5 5.3 1.5e-80 270.2 3.4 2.6 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 CCC70361.1 - 2.4e-26 92.2 0.0 4.9e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 CCC70361.1 - 2.8e-15 57.0 0.0 5.2e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 CCC70361.1 - 0.0032 17.9 0.1 0.03 14.8 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Complex1_LYR PF05347.15 CCC70362.1 - 1.9e-16 59.9 1.6 2.5e-16 59.5 1.6 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 CCC70362.1 - 0.001 19.8 1.1 0.0011 19.6 1.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 CCC70362.1 - 0.023 15.3 0.1 0.027 15.1 0.1 1.1 1 0 0 1 1 1 0 Complex1_LYR-like DnaJ-X PF14308.6 CCC70363.1 - 1.9e-59 200.7 8.9 1.9e-59 200.7 8.9 1.7 1 1 1 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 CCC70363.1 - 1e-26 92.8 0.6 3.7e-26 91.0 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain TipAS PF07739.13 CCC70363.1 - 0.16 12.5 2.7 0.81 10.2 0.3 2.9 2 1 1 3 3 3 0 TipAS antibiotic-recognition domain Enkurin PF13864.6 CCC70363.1 - 1.2 9.6 14.0 0.64 10.5 8.4 2.9 3 0 0 3 3 3 0 Calmodulin-binding YtxH PF12732.7 CCC70363.1 - 3.1 8.4 9.3 0.51 10.9 2.7 2.9 2 1 1 3 3 3 0 YtxH-like protein PRKCSH-like PF12999.7 CCC70363.1 - 3.9 7.2 5.1 15 5.3 1.9 2.7 3 0 0 3 3 3 0 Glucosidase II beta subunit-like DUF5314 PF17241.2 CCC70364.1 - 0.00093 18.9 0.1 0.0015 18.2 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5314) eIF3g PF12353.8 CCC70364.1 - 0.032 14.6 2.2 0.078 13.4 2.2 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Arrestin_C PF02752.22 CCC70367.1 - 4e-09 37.0 3.1 3.8e-07 30.6 0.0 3.6 3 1 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Got1 PF04178.12 CCC70368.1 - 3e-32 111.4 19.7 3e-32 111.4 19.7 1.5 1 1 0 1 1 1 1 Got1/Sft2-like family SLC3A2_N PF16028.5 CCC70368.1 - 0.0052 16.3 1.6 0.006 16.1 0.0 1.9 2 0 0 2 2 2 1 Solute carrier family 3 member 2 N-terminus DUF2207 PF09972.9 CCC70368.1 - 4.8 5.8 10.6 91 1.6 10.6 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) HLH PF00010.26 CCC70369.1 - 2.3e-12 46.6 0.1 4.9e-12 45.6 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain zinc_ribbon_16 PF17034.5 CCC70370.1 - 1e-23 83.9 12.2 6.7e-16 58.6 4.3 3.1 3 0 0 3 3 3 2 Zinc-ribbon like family Zn_ribbon_17 PF17120.5 CCC70370.1 - 2.1e-05 24.0 7.6 5.9e-05 22.6 7.6 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 CCC70370.1 - 0.053 14.4 9.2 2.9 8.9 0.3 4.3 4 0 0 4 4 4 0 WD domain, G-beta repeat GLTT PF01744.20 CCC70370.1 - 0.16 11.8 0.6 0.38 10.6 0.6 1.6 1 0 0 1 1 1 0 GLTT repeat (6 copies) Pkinase PF00069.25 CCC70371.1 - 3.1e-60 203.8 0.1 1.3e-59 201.8 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70371.1 - 3.8e-35 121.4 0.0 8.6e-35 120.3 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.16 CCC70371.1 - 7.7e-23 80.4 18.5 6.7e-14 51.8 3.0 3.2 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.22 CCC70371.1 - 1.3e-19 69.8 36.8 2.5e-11 43.3 14.9 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.24 CCC70371.1 - 6.1e-12 46.0 2.0 6.1e-12 46.0 2.0 2.5 3 0 0 3 3 3 1 Protein kinase C terminal domain C2 PF00168.30 CCC70371.1 - 5.2e-06 26.7 0.0 1.6e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 C2 domain Kinase-like PF14531.6 CCC70371.1 - 4.4e-05 22.9 0.9 0.0013 18.1 0.0 2.9 2 1 1 3 3 3 1 Kinase-like Uds1 PF15456.6 CCC70371.1 - 0.0056 16.9 1.1 0.0056 16.9 1.1 3.8 3 1 0 3 3 3 1 Up-regulated During Septation B2-adapt-app_C PF09066.10 CCC70371.1 - 0.067 13.3 0.1 0.27 11.3 0.0 2.1 2 0 0 2 2 2 0 Beta2-adaptin appendage, C-terminal sub-domain zf-RING_9 PF13901.6 CCC70371.1 - 2.3 8.2 29.7 0.57 10.1 7.6 3.5 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon Lgl_C PF08596.10 CCC70372.1 - 7.4e-141 469.4 0.1 2.6e-140 467.6 0.1 1.9 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal ANAPC4_WD40 PF12894.7 CCC70372.1 - 4.5e-09 36.5 0.7 0.0026 18.0 0.0 6.3 5 2 2 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCC70372.1 - 7.9e-05 23.4 0.3 3.1 8.8 0.0 4.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Cid2 PF09774.9 CCC70373.1 - 4e-35 121.6 5.3 4e-35 121.6 5.3 1.6 2 0 0 2 2 2 1 Caffeine-induced death protein 2 AIM24 PF01987.17 CCC70374.1 - 2.7e-28 99.1 0.0 3.8e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 NuA4 PF09340.10 CCC70375.1 - 3.3e-24 84.5 1.0 3.3e-24 84.5 1.0 1.8 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Pinin_SDK_memA PF04696.13 CCC70375.1 - 0.19 11.8 11.7 1.7 8.7 3.9 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Selenoprotein_S PF06936.11 CCC70375.1 - 0.44 10.3 4.7 0.42 10.4 1.2 2.0 2 0 0 2 2 2 0 Selenoprotein S (SelS) DivIC PF04977.15 CCC70375.1 - 0.54 10.1 15.1 1.7 8.4 1.1 2.1 2 0 0 2 2 2 0 Septum formation initiator LCD1 PF09798.9 CCC70375.1 - 0.96 7.9 9.0 1.5 7.2 9.0 1.2 1 1 0 1 1 1 0 DNA damage checkpoint protein YabA PF06156.13 CCC70375.1 - 7 7.4 10.1 0.42 11.3 3.0 2.0 1 1 1 2 2 2 0 Initiation control protein YabA DUF812 PF05667.11 CCC70375.1 - 8.9 5.1 14.8 2 7.2 0.6 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF812) Spc42p PF11544.8 CCC70376.1 - 0.055 13.5 1.1 0.055 13.5 1.1 2.5 3 1 0 3 3 3 0 Spindle pole body component Spc42p SlyX PF04102.12 CCC70376.1 - 0.27 11.9 0.2 0.27 11.9 0.2 2.6 3 0 0 3 3 3 0 SlyX PTPRCAP PF15713.5 CCC70376.1 - 6.3 7.1 7.3 8.7 6.6 0.8 2.3 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated PCI PF01399.27 CCC70377.1 - 2.9e-06 27.7 0.1 7.3e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 PCI domain Yeast-kill-tox PF09207.11 CCC70377.1 - 0.067 13.8 0.0 0.16 12.6 0.0 1.6 1 0 0 1 1 1 0 Yeast killer toxin TPR_2 PF07719.17 CCC70377.1 - 0.11 12.7 0.1 19 5.7 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Vg_Tdu PF07545.14 CCC70377.1 - 0.15 11.9 0.3 0.35 10.7 0.3 1.6 1 0 0 1 1 1 0 Vestigial/Tondu family Tmemb_14 PF03647.13 CCC70379.1 - 2.3e-12 47.5 4.4 2.5e-12 47.4 4.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1622 PF07784.11 CCC70379.1 - 0.018 15.0 0.1 0.02 14.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1622) AA_kinase PF00696.28 CCC70381.1 - 9.4e-41 140.0 0.0 1.9e-40 139.0 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 CCC70381.1 - 5.1e-13 48.5 1.2 2.4e-05 24.0 0.1 2.9 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.6 CCC70381.1 - 2.7e-08 33.5 2.1 5.8e-06 26.0 0.3 2.5 2 0 0 2 2 2 2 ACT domain CBM_17_28 PF03424.14 CCC70381.1 - 0.048 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 17/28) DUF1810 PF08837.11 CCC70381.1 - 0.11 12.4 0.2 0.34 10.7 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1810) Mito_carr PF00153.27 CCC70382.1 - 7.5e-45 150.8 2.7 3.1e-16 59.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Vma12 PF11712.8 CCC70383.1 - 0.078 13.0 0.3 0.08 13.0 0.3 1.0 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CBM_21 PF03370.13 CCC70384.1 - 8.9e-29 99.9 1.5 1.7e-28 99.0 0.5 2.0 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CCC70384.1 - 1.8e-11 44.5 2.4 4.9e-11 43.1 2.4 1.8 1 0 0 1 1 1 1 Starch/carbohydrate-binding module (family 53) HisG PF01634.18 CCC70385.1 - 3.5e-52 176.6 0.1 4.8e-52 176.1 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 CCC70385.1 - 6.8e-28 96.6 0.0 1.1e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 HisG, C-terminal domain Transp_cyt_pur PF02133.15 CCC70386.1 - 4.5e-89 299.2 35.4 5.2e-89 299.0 35.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin VIT1 PF01988.19 CCC70386.1 - 0.054 13.4 1.6 0.091 12.6 0.0 2.2 2 0 0 2 2 2 0 VIT family Transp_cyt_pur PF02133.15 CCC70387.1 - 2.6e-94 316.5 35.5 3e-94 316.3 35.5 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.15 CCC70388.1 - 6.4e-75 252.6 37.1 7.5e-75 252.4 37.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ketoacyl-synt PF00109.26 CCC70389.1 - 1.1e-56 192.2 0.0 1.5e-56 191.8 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 CCC70389.1 - 1.7e-32 111.9 0.0 2.9e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 CCC70389.1 - 0.038 13.4 0.1 0.073 12.4 0.1 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Sad1_UNC PF07738.13 CCC70389.1 - 0.068 13.2 0.0 4.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal Transp_cyt_pur PF02133.15 CCC70390.1 - 6.3e-97 325.1 38.1 7.3e-97 324.9 38.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin VIT1 PF01988.19 CCC70390.1 - 0.041 13.7 0.1 0.041 13.7 0.1 2.1 2 0 0 2 2 2 0 VIT family Sugar_tr PF00083.24 CCC70391.1 - 3.3e-165 550.3 34.7 3.8e-165 550.1 34.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC70391.1 - 2.2e-30 105.8 44.4 9.1e-27 93.9 22.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CCC70391.1 - 9.5e-05 21.0 2.1 0.00018 20.1 1.4 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector Cyclin PF08613.11 CCC70392.1 - 1e-42 146.3 0.6 1e-42 146.3 0.6 2.2 2 0 0 2 2 2 1 Cyclin PET117 PF15786.5 CCC70393.1 - 1.1e-31 108.9 2.0 1.6e-31 108.4 2.0 1.3 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial Sugar_tr PF00083.24 CCC70393.1 - 0.074 11.9 0.0 0.082 11.7 0.0 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Ribonuc_L-PSP PF01042.21 CCC70394.1 - 8.5e-42 142.0 1.3 9.5e-42 141.8 1.3 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ribosomal_L34e PF01199.18 CCC70395.1 - 3.3e-42 142.7 3.6 3.3e-42 142.7 3.6 1.7 2 0 0 2 2 2 1 Ribosomal protein L34e Vps36-NZF-N PF16988.5 CCC70395.1 - 0.098 12.1 1.9 0.11 11.9 0.1 2.1 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain Transp_cyt_pur PF02133.15 CCC70396.1 - 1.2e-74 251.7 37.9 1.4e-74 251.5 37.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin NAT PF04768.13 CCC70397.1 - 8.6e-56 188.2 0.4 2.1e-55 187.0 0.1 1.8 2 0 0 2 2 2 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase Semialdhyde_dh PF01118.24 CCC70397.1 - 6.2e-31 107.4 0.0 1.3e-30 106.3 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 CCC70397.1 - 2.2e-24 86.4 0.0 4.8e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.20 CCC70397.1 - 0.04 14.0 0.0 0.13 12.4 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus U1snRNP70_N PF12220.8 CCC70398.1 - 7.9e-21 74.5 1.4 1.6e-20 73.5 1.4 1.5 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.22 CCC70398.1 - 6.9e-17 61.0 0.0 1.5e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC70398.1 - 5.7e-05 23.1 0.0 0.00018 21.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif zf-RING_4 PF14570.6 CCC70399.1 - 2e-20 72.3 13.5 3.8e-20 71.4 13.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 CCC70399.1 - 1.1e-06 28.4 7.8 1.1e-06 28.4 7.8 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 CCC70399.1 - 3.4e-06 26.8 0.1 4.8e-05 23.1 0.1 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.12 CCC70399.1 - 4.6e-06 26.2 0.7 4.6e-06 26.2 0.7 2.7 3 0 0 3 3 3 1 Rtf2 RING-finger Baculo_IE-1 PF05290.11 CCC70399.1 - 5.5e-05 23.1 2.7 0.00013 21.9 2.7 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-RING_2 PF13639.6 CCC70399.1 - 0.0019 18.5 10.5 0.0038 17.5 10.5 1.5 1 0 0 1 1 1 1 Ring finger domain SET_assoc PF11767.8 CCC70399.1 - 0.0085 15.7 0.0 0.037 13.7 0.0 2.0 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated Prok-RING_4 PF14447.6 CCC70399.1 - 0.0092 15.8 9.1 0.12 12.2 9.4 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 CCC70399.1 - 0.0093 15.8 10.9 0.02 14.7 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 CCC70399.1 - 0.056 13.6 5.2 0.12 12.6 5.2 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger PAP_PilO PF06864.12 CCC70399.1 - 0.11 11.3 4.0 0.21 10.4 4.0 1.4 1 0 0 1 1 1 0 Pilin accessory protein (PilO) PocR PF10114.9 CCC70399.1 - 0.23 11.2 4.6 0.35 10.6 1.8 2.3 2 0 0 2 2 2 0 Sensory domain found in PocR zf-RING_5 PF14634.6 CCC70399.1 - 0.24 11.4 9.8 0.47 10.5 9.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain FYDLN_acid PF09538.10 CCC70399.1 - 4.1 8.1 5.9 1.8 9.3 0.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-RING_UBOX PF13445.6 CCC70399.1 - 5.4 7.1 10.1 14 5.8 10.1 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CCC70399.1 - 8.6 6.6 11.1 1e+02 3.2 11.0 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING RGI1 PF10843.8 CCC70400.1 - 7.8e-28 97.4 11.4 1.6e-27 96.4 11.4 1.4 1 1 0 1 1 1 1 Respiratory growth induced protein 1 HEPN_RiboL-PSP PF18735.1 CCC70400.1 - 0.021 14.8 4.3 0.027 14.4 4.3 1.2 1 0 0 1 1 1 0 RiboL-PSP-HEPN Spore_GerAC PF05504.11 CCC70400.1 - 0.47 10.6 5.3 1.6 9.0 5.3 1.7 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal ICL PF00463.21 CCC70401.1 - 3.8e-286 949.6 1.7 4.4e-286 949.4 1.7 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.6 CCC70401.1 - 1.1e-10 41.5 0.0 2.3e-10 40.3 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Vhr1 PF04001.13 CCC70402.1 - 6.3e-45 151.4 3.9 1.2e-44 150.5 3.9 1.4 1 0 0 1 1 1 1 Transcription factor Vhr1 HAD_2 PF13419.6 CCC70403.1 - 3.3e-16 59.9 0.0 4.2e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCC70403.1 - 1e-08 35.8 0.0 1.9e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 CCC70403.1 - 0.0044 17.4 0.0 0.006 17.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCC70403.1 - 0.033 14.3 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 HAD-hyrolase-like P16-Arc PF04699.14 CCC70404.1 - 1.9e-45 155.0 0.0 2.1e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Sigma70_r4 PF04545.16 CCC70404.1 - 0.16 11.5 0.0 0.52 9.9 0.0 1.9 2 0 0 2 2 2 0 Sigma-70, region 4 Ribonuc_red_lgC PF02867.15 CCC70405.1 - 7.5e-183 608.8 0.0 9.3e-183 608.5 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 CCC70405.1 - 7e-22 77.2 0.0 1.6e-21 76.1 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 CCC70405.1 - 8.7e-19 67.9 0.0 2.5e-18 66.4 0.0 1.9 1 0 0 1 1 1 1 ATP cone domain Sec6 PF06046.13 CCC70406.1 - 1.2e-166 555.5 16.7 1.2e-166 555.5 16.7 1.9 2 1 0 2 2 2 1 Exocyst complex component Sec6 Adaptin_binding PF10199.9 CCC70406.1 - 0.057 14.0 0.0 0.47 11.1 0.0 2.3 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Vps53_N PF04100.12 CCC70406.1 - 6.1 5.7 30.2 0.11 11.4 5.0 3.7 4 0 0 4 4 4 0 Vps53-like, N-terminal Tctex-1 PF03645.13 CCC70407.1 - 2.3e-08 34.2 0.1 2.8e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.15 CCC70408.1 - 1.1e-14 54.6 2.1 1.1e-14 54.6 2.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5337 PF17272.2 CCC70408.1 - 0.32 10.9 2.5 0.91 9.4 2.5 1.9 1 1 0 1 1 1 0 Family of unknown function (DUF5337) Aldedh PF00171.22 CCC70409.1 - 9.7e-184 611.2 0.8 1.1e-183 611.0 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_S24e PF01282.19 CCC70410.1 - 9.5e-35 118.4 0.2 1.6e-34 117.7 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S24e Yos1 PF08571.10 CCC70411.1 - 7.6e-31 106.2 1.2 8.5e-31 106.1 1.2 1.0 1 0 0 1 1 1 1 Yos1-like Y_phosphatase PF00102.27 CCC70412.1 - 1.2e-50 172.2 0.5 1.2e-50 172.2 0.5 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Rhodanese PF00581.20 CCC70412.1 - 6.1e-09 36.4 0.0 2.9e-08 34.2 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain Y_phosphatase3 PF13350.6 CCC70412.1 - 0.014 15.3 0.0 0.028 14.4 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 CCC70412.1 - 0.044 13.6 0.0 0.25 11.2 0.0 2.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain HDV_ag PF01517.18 CCC70413.1 - 0.26 11.1 0.0 0.38 10.5 0.0 1.1 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen PPR_2 PF13041.6 CCC70414.1 - 2.3e-15 56.5 1.4 1.6e-09 37.8 0.2 3.7 2 1 1 3 3 3 2 PPR repeat family TFIID_NTD2 PF04494.15 CCC70414.1 - 0.017 15.3 2.0 2 8.7 0.1 3.3 2 1 1 3 3 3 0 WD40 associated region in TFIID subunit, NTD2 domain PPR_3 PF13812.6 CCC70414.1 - 0.021 14.9 0.0 0.1 12.7 0.0 2.2 1 0 0 1 1 1 0 Pentatricopeptide repeat domain DRE2_N PF16803.5 CCC70414.1 - 0.082 13.2 0.0 0.33 11.2 0.0 2.1 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Peptidase_M24 PF00557.24 CCC70415.1 - 2.3e-51 174.4 0.0 3.1e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 CCC70415.1 - 8e-34 116.0 0.0 2.3e-33 114.6 0.0 1.8 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain WAPL PF07814.13 CCC70415.1 - 0.026 13.3 0.1 0.042 12.6 0.1 1.3 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin APH PF01636.23 CCC70417.1 - 1.1e-08 35.3 0.0 3.1e-08 33.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sulfatase_C PF14707.6 CCC70417.1 - 0.087 13.6 0.1 0.34 11.6 0.1 2.0 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase DUF5601 PF18151.1 CCC70417.1 - 0.12 12.8 0.3 15 6.0 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5601) 2-Hacid_dh_C PF02826.19 CCC70418.1 - 6.7e-54 181.9 0.0 1e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 CCC70418.1 - 7.9e-39 132.4 0.1 1e-38 132.0 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.21 CCC70418.1 - 3e-05 24.1 0.1 6.5e-05 23.0 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.15 CCC70418.1 - 0.00011 22.4 0.3 0.00028 21.1 0.3 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 CCC70418.1 - 0.0024 17.6 0.1 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 ACT domain XdhC_C PF13478.6 CCC70418.1 - 0.0037 17.8 0.0 0.019 15.4 0.0 2.0 2 0 0 2 2 2 1 XdhC Rossmann domain IlvN PF07991.12 CCC70418.1 - 0.018 14.6 0.1 0.038 13.6 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain AceK PF06315.11 CCC70418.1 - 0.14 10.6 0.2 0.25 9.8 0.0 1.4 2 0 0 2 2 2 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Acetyltransf_1 PF00583.25 CCC70418.1 - 0.15 12.3 0.0 0.3 11.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family DUF2703 PF10865.8 CCC70418.1 - 0.24 11.6 0.8 3.7 7.7 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) RPN2_C PF18004.1 CCC70419.1 - 1.3e-51 174.7 10.6 2.1e-51 174.0 10.6 1.3 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 CCC70419.1 - 2e-33 113.1 21.9 8.9e-07 29.1 0.6 9.2 9 0 0 9 9 9 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 CCC70419.1 - 1.1e-16 61.0 6.1 2.9e-13 50.0 0.1 5.2 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.6 CCC70419.1 - 2.4e-07 31.1 5.3 0.16 12.5 0.0 5.9 5 2 2 7 7 7 4 HEAT-like repeat HEAT PF02985.22 CCC70419.1 - 3.7e-07 29.8 0.9 1.8 9.0 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat DUF669 PF05037.13 CCC70419.1 - 0.011 15.9 0.0 0.026 14.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF669) RICTOR_V PF14668.6 CCC70419.1 - 0.02 15.1 0.1 0.2 11.9 0.0 2.8 1 1 2 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Arm PF00514.23 CCC70419.1 - 0.046 13.8 3.8 57 3.9 0.0 4.7 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF4775 PF16001.5 CCC70419.1 - 0.057 12.8 13.6 0.082 12.3 13.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4775) Telomere_reg-2 PF10193.9 CCC70419.1 - 0.25 11.8 5.4 14 6.2 0.0 4.0 3 1 0 3 3 3 0 Telomere length regulation protein Striatin PF08232.12 CCC70419.1 - 0.4 11.3 9.2 0.73 10.4 9.2 1.3 1 0 0 1 1 1 0 Striatin family Cnd1 PF12717.7 CCC70419.1 - 0.41 10.7 6.4 1.7 8.6 0.1 3.5 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 RNA_pol_Rpc4 PF05132.14 CCC70419.1 - 3.9 7.9 6.6 6.8 7.1 6.6 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 NARP1 PF12569.8 CCC70419.1 - 4.3 6.1 14.1 8.8 5.1 14.1 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BING4CT PF08149.11 CCC70420.1 - 9.2e-37 124.7 0.0 1.7e-34 117.4 0.0 3.4 3 0 0 3 3 3 1 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 CCC70420.1 - 0.0001 22.5 0.0 5.9 7.3 0.0 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCC70420.1 - 0.00063 20.5 0.0 0.44 11.5 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat HIT PF01230.23 CCC70421.1 - 1.3e-18 67.5 0.0 1.9e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 CCC70421.1 - 6e-07 29.9 1.1 9.3e-07 29.3 0.2 1.8 2 1 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.15 CCC70421.1 - 0.022 14.6 0.6 0.048 13.5 0.6 1.7 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 FAD-oxidase_C PF02913.19 CCC70422.1 - 1.5e-62 211.5 0.0 2.9e-62 210.6 0.0 1.4 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CCC70422.1 - 1.1e-30 106.2 0.5 1.7e-30 105.6 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain DUF4108 PF13390.6 CCC70423.1 - 0.13 12.2 1.2 7.6 6.4 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) zf-CCHC PF00098.23 CCC70426.1 - 0.00026 20.9 3.0 0.00026 20.9 3.0 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_5 PF14787.6 CCC70426.1 - 0.19 11.4 11.6 0.66 9.7 1.4 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_4 PF14392.6 CCC70426.1 - 9.6 6.0 8.8 1 9.1 2.2 2.3 2 0 0 2 2 2 0 Zinc knuckle GET2 PF08690.10 CCC70427.1 - 1.6e-86 290.8 11.5 2.4e-85 286.9 11.5 1.9 1 1 0 1 1 1 1 GET complex subunit GET2 DUF4355 PF14265.6 CCC70427.1 - 2.3 8.5 5.2 0.9 9.8 1.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4355) AAA PF00004.29 CCC70428.1 - 9.3e-99 327.0 0.0 3.4e-48 163.4 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC70428.1 - 6.8e-24 83.4 3.4 8e-12 44.8 0.4 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 CCC70428.1 - 2.4e-14 53.8 0.0 3.8e-07 30.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 CCC70428.1 - 2.9e-14 53.1 0.0 9.3e-06 25.5 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCC70428.1 - 8.5e-14 52.3 0.1 0.0011 19.4 0.1 4.8 3 2 1 4 4 4 2 AAA ATPase domain AAA_33 PF13671.6 CCC70428.1 - 2.2e-11 44.1 0.0 7.1e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 CCC70428.1 - 2.8e-11 43.6 1.1 1.3e-05 25.2 0.1 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) TIP49 PF06068.13 CCC70428.1 - 1.5e-09 37.6 0.1 0.00099 18.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_22 PF13401.6 CCC70428.1 - 2.3e-09 37.7 0.8 0.05 13.9 0.0 4.1 2 2 2 4 4 4 2 AAA domain RNA_helicase PF00910.22 CCC70428.1 - 1.1e-07 32.2 0.0 0.0058 17.0 0.0 2.9 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.21 CCC70428.1 - 1.6e-07 30.9 0.5 0.017 14.5 0.0 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 CCC70428.1 - 3.3e-07 30.4 0.0 0.016 15.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 CCC70428.1 - 4.2e-07 29.5 1.0 0.18 11.1 0.0 3.5 2 1 1 3 3 3 2 KaiC IstB_IS21 PF01695.17 CCC70428.1 - 5.9e-07 29.4 0.0 0.021 14.6 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 CCC70428.1 - 2.2e-06 27.6 0.1 0.057 13.1 0.0 3.3 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.6 CCC70428.1 - 2.8e-06 27.9 0.1 0.13 12.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_7 PF12775.7 CCC70428.1 - 4.3e-06 26.4 0.1 0.056 13.0 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 CCC70428.1 - 5.9e-06 26.1 0.1 0.13 11.9 0.0 3.6 3 1 0 3 3 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.18 CCC70428.1 - 1.3e-05 25.2 0.0 0.021 14.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_25 PF13481.6 CCC70428.1 - 1.4e-05 24.8 5.9 0.12 12.0 0.4 4.2 2 2 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.17 CCC70428.1 - 2.1e-05 23.8 0.1 0.11 11.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ABC_tran PF00005.27 CCC70428.1 - 2.1e-05 25.0 0.0 0.067 13.7 0.0 3.6 3 1 0 3 3 2 1 ABC transporter PhoH PF02562.16 CCC70428.1 - 2.5e-05 23.8 0.5 0.13 11.7 0.1 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_28 PF13521.6 CCC70428.1 - 2.9e-05 24.4 0.0 0.37 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.13 CCC70428.1 - 3.1e-05 23.3 0.0 0.058 12.5 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF815) AAA_17 PF13207.6 CCC70428.1 - 3.5e-05 24.3 0.1 0.36 11.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_3 PF07726.11 CCC70428.1 - 7.8e-05 22.5 0.0 0.51 10.2 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CCC70428.1 - 0.00014 21.8 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 CCC70428.1 - 0.00018 21.6 0.0 0.088 12.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_11 PF13086.6 CCC70428.1 - 0.0002 21.3 0.3 0.55 10.0 0.0 2.7 3 0 0 3 3 2 2 AAA domain DUF2075 PF09848.9 CCC70428.1 - 0.00034 20.0 0.0 0.69 9.1 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 CCC70428.1 - 0.0004 20.3 0.1 1.5 8.7 0.0 3.3 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 CCC70428.1 - 0.00067 19.4 0.3 1.6 8.4 0.1 2.5 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 CCC70428.1 - 0.00068 19.6 0.1 1.8 8.5 0.1 3.5 3 1 0 3 3 2 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 CCC70428.1 - 0.0023 18.3 1.6 2 8.7 0.0 3.2 3 1 0 4 4 3 1 AAA domain Sigma54_activ_2 PF14532.6 CCC70428.1 - 0.0043 17.2 0.0 0.94 9.6 0.0 2.9 3 0 0 3 3 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 CCC70428.1 - 0.0085 15.4 0.0 4.9 6.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin IPT PF01745.16 CCC70428.1 - 0.0087 15.5 0.1 1.5 8.1 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase NB-ARC PF00931.22 CCC70428.1 - 0.016 14.4 0.0 3.7 6.7 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Zot PF05707.12 CCC70428.1 - 0.019 14.6 0.1 1.7 8.2 0.0 3.2 2 2 0 2 2 2 0 Zonular occludens toxin (Zot) Cytidylate_kin PF02224.18 CCC70428.1 - 0.021 14.6 0.1 5.2 6.7 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase KAP_NTPase PF07693.14 CCC70428.1 - 0.023 14.0 0.4 1.5 8.0 0.0 2.9 2 2 1 4 4 4 0 KAP family P-loop domain NTPase_1 PF03266.15 CCC70428.1 - 0.038 13.9 2.3 5.7 6.8 0.0 4.0 4 1 1 5 5 4 0 NTPase AAA_6 PF12774.7 CCC70428.1 - 0.05 12.6 0.3 3.6 6.5 0.0 2.6 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region CDC48_2 PF02933.17 CCC70428.1 - 0.09 12.6 0.1 0.25 11.2 0.1 1.8 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 DEAD PF00270.29 CCC70428.1 - 0.099 12.4 0.5 60 3.3 0.1 3.9 3 1 0 4 4 4 0 DEAD/DEAH box helicase Cyclin_N PF00134.23 CCC70429.1 - 1.4e-15 57.1 0.3 2.2e-15 56.6 0.3 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCC70429.1 - 9.6e-05 22.8 0.1 9.6e-05 22.8 0.1 2.1 2 1 0 2 2 2 1 Cyclin Mlf1IP PF10248.9 CCC70429.1 - 0.82 9.6 4.0 1.2 9.1 4.0 1.2 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Na_Ca_ex PF01699.24 CCC70430.1 - 9.6e-48 162.0 37.7 1.2e-25 90.3 10.9 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein YWFCY PF14293.6 CCC70430.1 - 0.083 13.2 0.6 0.45 10.9 0.0 2.4 2 0 0 2 2 2 0 YWFCY protein Macoilin PF09726.9 CCC70431.1 - 0.01 14.4 2.6 0.014 14.0 2.6 1.1 1 0 0 1 1 1 0 Macoilin family Ribosomal_60s PF00428.19 CCC70432.1 - 3.3e-24 85.3 12.0 3.9e-24 85.0 12.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein IATP PF04568.12 CCC70433.1 - 3.3e-12 46.7 0.2 3.7e-12 46.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HMGL-like PF00682.19 CCC70434.1 - 7.9e-85 284.6 0.1 1.2e-84 284.1 0.1 1.2 1 0 0 1 1 1 1 HMGL-like SidE PF12252.8 CCC70434.1 - 0.035 11.7 0.1 0.049 11.2 0.1 1.1 1 0 0 1 1 1 0 Dot/Icm substrate protein Trp_syntA PF00290.20 CCC70434.1 - 0.092 11.6 0.0 9.3 5.0 0.0 2.3 2 0 0 2 2 2 0 Tryptophan synthase alpha chain FliG_N PF14842.6 CCC70434.1 - 0.12 13.0 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 FliG N-terminal domain Mit_KHE1 PF10173.9 CCC70435.1 - 2.6e-57 194.0 2.1 3.3e-57 193.7 2.1 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Ribosomal_L41 PF05162.13 CCC70436.1 - 1.2e-10 41.2 26.3 1.3e-10 41.2 26.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 Metallophos PF00149.28 CCC70438.1 - 1.5e-32 113.7 0.2 2.5e-32 113.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase R3H PF01424.22 CCC70439.1 - 1.3e-10 41.1 0.0 3.1e-10 39.9 0.0 1.7 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 CCC70439.1 - 0.012 16.4 2.7 0.028 15.2 2.7 1.6 1 0 0 1 1 1 0 SUZ domain SR-25 PF10500.9 CCC70439.1 - 0.36 10.4 9.8 0.54 9.8 9.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ufd2P_core PF10408.9 CCC70440.1 - 1.6e-195 651.4 13.8 1.6e-195 651.4 13.8 1.4 2 0 0 2 2 2 1 Ubiquitin elongating factor core U-box PF04564.15 CCC70440.1 - 8.4e-29 99.6 1.0 2.6e-28 98.0 1.0 1.9 1 0 0 1 1 1 1 U-box domain Ribosomal_L29 PF00831.23 CCC70441.1 - 5.2e-16 58.3 3.2 5.2e-16 58.3 3.2 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein PilJ PF13675.6 CCC70441.1 - 0.28 11.2 5.6 0.12 12.4 0.7 2.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term MRP-L47 PF06984.13 CCC70441.1 - 0.3 11.2 3.5 0.29 11.3 0.8 2.3 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF4972 PF16342.5 CCC70441.1 - 0.92 9.2 4.8 6.5 6.5 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) Arf PF00025.21 CCC70442.1 - 3.4e-78 261.1 0.0 3.9e-78 260.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 CCC70442.1 - 1.4e-14 54.3 0.1 1.9e-14 53.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 CCC70442.1 - 3.5e-14 52.7 0.0 3.7e-14 52.6 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 CCC70442.1 - 7.4e-14 51.6 0.0 8.9e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 CCC70442.1 - 5.5e-12 45.5 1.0 4.1e-08 32.8 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 CCC70442.1 - 1.4e-09 37.7 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 CCC70442.1 - 1.9e-05 24.7 0.0 3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRP54 PF00448.22 CCC70442.1 - 0.0081 15.8 0.2 0.015 14.9 0.2 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 CCC70442.1 - 0.039 14.5 0.1 0.072 13.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 CCC70442.1 - 0.041 14.1 0.6 0.1 12.8 0.6 1.9 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 CCC70442.1 - 0.051 12.9 0.2 0.074 12.3 0.1 1.5 1 1 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.19 CCC70442.1 - 0.053 13.1 0.1 7.5 6.1 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 CCC70442.1 - 0.056 13.0 0.1 0.16 11.5 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 CCC70442.1 - 0.062 13.2 0.1 8.9 6.2 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 CCC70442.1 - 0.09 13.3 0.1 0.14 12.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 CCC70442.1 - 0.15 12.0 0.4 14 5.6 0.0 2.1 2 0 0 2 2 2 0 NACHT domain Sugar_tr PF00083.24 CCC70444.1 - 7.3e-130 433.8 29.7 9.1e-130 433.5 29.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC70444.1 - 2.4e-20 72.8 33.7 2e-14 53.3 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pex14_N PF04695.13 CCC70444.1 - 0.44 11.2 8.8 0.14 12.8 1.6 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sec31 PF11549.8 CCC70445.1 - 2.2e-17 62.7 0.6 9.7e-17 60.6 0.6 2.2 1 0 0 1 1 1 1 Protein transport protein SEC31 WD40 PF00400.32 CCC70445.1 - 4e-08 33.8 11.0 0.12 13.3 0.0 6.8 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC70445.1 - 3.8e-07 30.3 1.0 2.3 8.6 0.1 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Sec16_C PF12931.7 CCC70445.1 - 6.8e-06 26.0 1.5 2.1e-05 24.4 1.5 1.7 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 SRA1 PF07304.11 CCC70445.1 - 7.3e-06 25.8 5.2 7.3e-06 25.8 5.2 3.1 3 1 0 3 3 3 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 CCC70445.1 - 0.00014 21.9 0.5 0.00065 19.8 0.5 2.1 1 1 0 1 1 1 1 Prp18 domain eIF2A PF08662.11 CCC70445.1 - 0.00042 20.2 2.8 0.037 13.9 0.1 3.3 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A P16-Arc PF04699.14 CCC70445.1 - 0.00077 20.0 3.7 0.0014 19.2 2.3 2.2 2 0 0 2 2 2 1 ARP2/3 complex 16 kDa subunit (p16-Arc) CHCH PF06747.13 CCC70446.1 - 0.00091 19.3 6.9 0.00091 19.3 6.9 2.3 2 1 0 2 2 2 1 CHCH domain GCIP PF13324.6 CCC70446.1 - 0.013 15.1 2.0 0.015 14.9 2.0 1.1 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting MttA_Hcf106 PF02416.16 CCC70446.1 - 0.15 11.4 1.9 0.19 11.1 1.2 1.5 1 1 0 1 1 1 0 mttA/Hcf106 family Pro_isomerase PF00160.21 CCC70447.1 - 2.4e-44 151.4 0.0 5.1e-44 150.3 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 CCC70447.1 - 5.8e-05 22.9 2.2 0.059 13.5 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 CCC70447.1 - 0.0011 18.7 8.8 0.0063 16.3 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF4984 PF16372.5 CCC70447.1 - 0.052 13.5 0.0 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4984) Gas_vesicle_C PF01304.17 CCC70447.1 - 0.29 11.2 4.3 0.16 12.0 1.3 2.2 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain TPR_6 PF13174.6 CCC70447.1 - 0.41 11.4 5.0 2.7 8.8 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCC70447.1 - 0.41 11.0 0.0 0.41 11.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat CDP-OH_P_transf PF01066.21 CCC70448.1 - 3.1e-15 56.7 0.6 9.6e-15 55.1 0.6 1.9 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase SDA1 PF05285.12 CCC70449.1 - 1.3e-96 324.1 29.7 1.3e-96 324.1 29.7 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 CCC70449.1 - 1.1e-21 76.9 0.2 2.5e-21 75.7 0.2 1.7 1 0 0 1 1 1 1 NUC130/3NT domain ATP-grasp_2 PF08442.10 CCC70450.1 - 3.2e-72 242.3 1.9 5.2e-72 241.6 1.9 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 CCC70450.1 - 1.6e-25 89.7 0.2 3e-25 88.8 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 CCC70450.1 - 1.2e-05 24.9 0.5 3e-05 23.6 0.5 1.7 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 CCC70450.1 - 0.0067 16.2 0.4 0.02 14.7 0.4 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain MPC PF03650.13 CCC70451.1 - 3.2e-48 162.5 0.1 3.9e-48 162.2 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers ANTH PF07651.16 CCC70452.1 - 1.4e-54 185.0 0.6 1.4e-54 185.0 0.6 2.6 2 1 1 3 3 3 1 ANTH domain ENTH PF01417.20 CCC70452.1 - 3.1e-06 27.2 0.1 3.1e-06 27.2 0.1 2.7 2 1 1 3 3 3 1 ENTH domain FapA PF03961.13 CCC70452.1 - 0.036 12.7 4.8 0.057 12.0 4.8 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Phage_int_SAM_5 PF13102.6 CCC70452.1 - 0.16 12.3 2.6 2.5 8.5 0.0 2.7 2 0 0 2 2 2 0 Phage integrase SAM-like domain D123 PF07065.14 CCC70453.1 - 2.6e-115 384.8 4.9 3.5e-115 384.4 4.9 1.2 1 0 0 1 1 1 1 D123 BP28CT PF08146.12 CCC70453.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 BP28CT (NUC211) domain R2K_3 PF14243.6 CCC70453.1 - 0.14 12.2 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 TFIIB PF00382.19 CCC70454.1 - 3.2e-56 187.3 0.8 1.2e-27 95.7 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 CCC70454.1 - 4e-28 97.7 1.2 4e-28 97.7 1.2 2.5 2 1 0 2 2 2 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 CCC70454.1 - 1.2e-11 43.9 2.5 2.4e-11 42.9 2.5 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.23 CCC70454.1 - 0.00065 19.5 0.1 0.33 10.7 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Vps36-NZF-N PF16988.5 CCC70454.1 - 0.52 9.8 3.3 6.3 6.3 3.3 2.5 1 1 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain CPDase PF07823.11 CCC70455.1 - 9.4e-73 244.2 0.0 1.1e-72 244.0 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 CCC70455.1 - 0.00054 19.9 0.0 0.0041 17.0 0.0 2.0 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily DUF4071 PF13281.6 CCC70455.1 - 0.042 12.9 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) DUF3723 PF12520.8 CCC70455.1 - 0.064 11.9 0.1 1.9 7.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3723) Glucosamine_iso PF01182.20 CCC70456.1 - 1e-11 45.1 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HSF_DNA-bind PF00447.17 CCC70457.1 - 1.9e-24 86.1 3.8 3.5e-24 85.2 3.8 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding RRM_1 PF00076.22 CCC70458.1 - 1e-31 108.5 3.4 1.3e-11 44.2 0.1 6.2 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC70458.1 - 5.8e-06 26.3 0.0 0.0015 18.6 0.0 3.8 4 1 0 4 4 4 1 RNA recognition motif RRM_occluded PF16842.5 CCC70458.1 - 0.011 15.5 0.3 9.5 6.2 0.0 3.6 4 0 0 4 4 4 0 Occluded RNA-recognition motif Oxidored_FMN PF00724.20 CCC70459.1 - 6e-131 436.8 0.0 7e-131 436.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family PsaL PF02605.15 CCC70459.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI Bromodomain PF00439.25 CCC70460.1 - 5.9e-28 96.8 1.7 1.3e-27 95.6 1.7 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 CCC70460.1 - 2e-09 37.7 0.0 3.7e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCC70460.1 - 1.9e-06 27.8 0.2 4.8e-06 26.5 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCC70460.1 - 0.00034 21.0 0.1 0.00067 20.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCC70460.1 - 0.15 12.0 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein NOP19 PF10863.8 CCC70461.1 - 8.5e-60 200.7 13.1 8.5e-60 200.7 13.1 1.4 2 0 0 2 2 2 1 Nucleolar protein 19 TT_ORF2 PF02957.15 CCC70461.1 - 0.33 11.9 6.0 6.5 7.7 0.3 2.2 2 0 0 2 2 2 0 TT viral ORF2 DUF3245 PF11595.8 CCC70461.1 - 0.55 10.7 23.1 3.4 8.1 5.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) ALMT PF11744.8 CCC70461.1 - 3.4 6.4 11.0 4.2 6.1 11.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CRA PF06589.11 CCC70461.1 - 5.8 7.0 11.5 0.26 11.4 2.8 2.2 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) DEAD PF00270.29 CCC70462.1 - 1.6e-42 145.2 0.0 3.2e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC70462.1 - 6.2e-31 107.0 0.6 3.9e-30 104.4 0.1 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC70462.1 - 0.00017 21.7 0.0 0.00041 20.4 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3231 PF11553.8 CCC70463.1 - 0.014 15.1 0.8 0.044 13.4 0.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3231) XPG_N PF00752.17 CCC70465.1 - 7.1e-35 119.5 0.0 1.7e-34 118.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CCC70465.1 - 6.2e-26 90.6 0.0 6.2e-26 90.6 0.0 3.3 3 0 0 3 3 3 1 XPG I-region 5_3_exonuc PF01367.20 CCC70465.1 - 0.014 16.0 0.0 0.014 16.0 0.0 2.8 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold DUF1912 PF08930.10 CCC70466.1 - 0.028 14.6 1.8 0.08 13.1 1.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) MFS_1 PF07690.16 CCC70468.1 - 1.1e-30 106.8 26.6 1.1e-30 106.8 26.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Nmad2 PF18753.1 CCC70468.1 - 5.4 6.4 7.2 1.5 8.2 2.0 2.1 2 0 0 2 2 2 0 Nucleotide modification associated domain 2 Adaptin_N PF01602.20 CCC70469.1 - 5.9e-100 335.3 5.0 7.1e-100 335.0 5.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 CCC70469.1 - 2.5e-14 53.6 3.0 2.7e-12 47.1 0.0 3.5 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 CCC70469.1 - 2.2e-07 31.2 0.1 0.00049 20.4 0.0 5.0 4 2 2 6 6 6 2 HEAT repeats HEAT PF02985.22 CCC70469.1 - 6.2e-05 22.9 0.1 9.4 6.8 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat Cohesin_HEAT PF12765.7 CCC70469.1 - 0.014 15.7 1.7 0.14 12.5 0.1 2.7 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion GGA_N-GAT PF18308.1 CCC70469.1 - 0.041 13.5 0.0 0.18 11.4 0.0 2.2 1 0 0 1 1 1 0 GGA N-GAT domain DUF4499 PF14934.6 CCC70469.1 - 0.19 12.1 0.1 0.44 10.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) RR_TM4-6 PF06459.12 CCC70469.1 - 1.6 8.5 13.5 2.5 7.9 13.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DNA_pol_phi PF04931.13 CCC70469.1 - 1.8 6.6 22.9 3.6 5.6 22.9 1.4 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 CCC70469.1 - 6.9 4.8 13.9 10 4.3 13.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Tim54 PF11711.8 CCC70469.1 - 7.9 5.1 8.1 12 4.6 8.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Kdo PF06293.14 CCC70470.1 - 2.3e-08 33.6 0.0 5.4e-08 32.4 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CCC70470.1 - 9e-05 22.1 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 CCC70470.1 - 0.001 19.1 0.0 0.0084 16.1 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 CCC70470.1 - 0.0041 16.5 0.0 0.0047 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70470.1 - 0.11 11.8 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase Say1_Mug180 PF10340.9 CCC70471.1 - 2.5e-90 303.0 2.1 2e-89 300.1 2.1 1.9 1 1 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_3 PF07859.13 CCC70471.1 - 1.3e-17 64.3 0.0 6.5e-17 62.1 0.0 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 CCC70471.1 - 0.0049 15.8 0.0 1.4 7.7 0.0 2.2 2 0 0 2 2 2 2 Carboxylesterase family Chlorophyllase2 PF12740.7 CCC70471.1 - 0.091 11.7 0.0 4.8 6.0 0.0 2.3 1 1 0 2 2 2 0 Chlorophyllase enzyme Hydrolase_4 PF12146.8 CCC70471.1 - 0.1 11.9 0.0 0.28 10.4 0.0 1.6 1 1 1 2 2 2 0 Serine aminopeptidase, S33 PhoD PF09423.10 CCC70472.1 - 0.00086 18.4 0.0 0.012 14.6 0.0 2.3 1 1 0 1 1 1 1 PhoD-like phosphatase GTP_cyclohydroI PF01227.22 CCC70473.1 - 3.9e-78 261.0 0.6 4.7e-78 260.7 0.6 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 CCC70473.1 - 1.3e-05 25.3 0.0 4.6e-05 23.5 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein DnaJ_CXXCXGXG PF00684.19 CCC70474.1 - 1.2e-06 28.7 5.0 0.0076 16.6 0.5 2.3 2 0 0 2 2 2 2 DnaJ central domain HypA PF01155.19 CCC70474.1 - 0.21 11.6 1.3 3.7 7.6 0.3 2.1 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DEC-1_N PF04625.13 CCC70474.1 - 7.6 5.4 7.5 10 5.0 7.5 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region AAA PF00004.29 CCC70475.1 - 1.2e-51 174.6 0.0 1.3e-42 145.3 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC70475.1 - 6.4e-10 38.7 0.0 2.1e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CCC70475.1 - 7.5e-07 29.4 0.0 2.5e-05 24.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCC70475.1 - 7.6e-07 29.7 1.3 0.00019 21.9 0.1 3.0 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 CCC70475.1 - 2.5e-05 24.1 0.0 0.00021 21.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 CCC70475.1 - 9e-05 22.6 0.0 0.72 10.0 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.14 CCC70475.1 - 0.00018 21.5 0.0 0.00071 19.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 CCC70475.1 - 0.00045 20.3 1.8 0.0065 16.5 0.0 3.5 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit TIP49 PF06068.13 CCC70475.1 - 0.0019 17.5 0.5 0.032 13.4 0.0 2.5 3 0 0 3 3 2 1 TIP49 P-loop domain Sigma54_activat PF00158.26 CCC70475.1 - 0.0046 16.7 0.0 1.1 9.0 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 CCC70475.1 - 0.005 17.1 0.2 0.12 12.7 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 CCC70475.1 - 0.011 15.8 0.0 0.064 13.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 CCC70475.1 - 0.013 15.9 0.0 0.085 13.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.6 CCC70475.1 - 0.017 15.3 0.0 0.059 13.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CCC70475.1 - 0.024 15.1 3.7 0.13 12.8 0.0 3.5 3 0 0 3 3 3 0 ABC transporter AAA_3 PF07726.11 CCC70475.1 - 0.032 14.1 0.0 0.078 12.8 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCC70475.1 - 0.035 13.9 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 CCC70475.1 - 0.042 13.2 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 CCC70475.1 - 0.059 12.9 0.0 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Bromodomain PF00439.25 CCC70475.1 - 0.06 13.4 0.2 0.25 11.4 0.0 2.2 2 0 0 2 2 1 0 Bromodomain AAA_28 PF13521.6 CCC70475.1 - 0.065 13.5 0.1 0.42 10.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCC70475.1 - 0.085 12.4 0.0 0.3 10.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCC70475.1 - 0.13 12.8 2.6 0.25 11.9 0.0 2.9 2 1 0 2 2 1 0 AAA domain AAA_11 PF13086.6 CCC70475.1 - 0.6 9.9 0.0 0.6 9.9 0.0 3.7 3 0 0 3 3 3 0 AAA domain CDC45 PF02724.14 CCC70475.1 - 3.5 5.8 18.2 8.9 4.5 18.2 1.7 1 0 0 1 1 1 0 CDC45-like protein Sec63 PF02889.16 CCC70476.1 - 3.2e-122 406.6 0.1 1e-80 270.7 0.0 2.6 3 0 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 CCC70476.1 - 3e-50 170.4 0.6 9.6e-26 90.6 0.5 3.7 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.15 CCC70476.1 - 3.6e-29 102.0 0.0 8.9e-15 55.1 0.0 2.9 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCC70476.1 - 1.1e-19 70.8 0.0 1.2e-08 35.3 0.0 3.9 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 CCC70476.1 - 1e-05 25.8 5.5 0.031 14.5 0.1 4.3 3 2 0 3 3 3 2 AAA domain AAA PF00004.29 CCC70476.1 - 0.00031 21.2 6.0 0.58 10.6 0.0 4.2 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 CCC70476.1 - 0.00094 19.5 0.1 0.42 10.9 0.1 3.0 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CCC70476.1 - 0.0013 18.3 0.0 0.1 12.1 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein IstB_IS21 PF01695.17 CCC70476.1 - 0.0014 18.4 0.1 2.7 7.7 0.0 4.0 4 0 0 4 4 4 1 IstB-like ATP binding protein T2SSE PF00437.20 CCC70476.1 - 0.032 13.3 0.0 5.5 6.0 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Helicase_PWI PF18149.1 CCC70476.1 - 0.054 13.7 0.1 0.25 11.5 0.1 2.2 1 0 0 1 1 1 0 N-terminal helicase PWI domain AAA_16 PF13191.6 CCC70476.1 - 0.11 12.9 0.0 22 5.4 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain Efg1 PF10153.9 CCC70477.1 - 1.2e-34 119.0 13.1 1.2e-34 119.0 13.1 1.9 2 0 0 2 2 2 1 rRNA-processing protein Efg1 PWWP PF00855.17 CCC70477.1 - 0.042 14.3 2.3 1.9 8.9 0.8 2.6 1 1 1 2 2 2 0 PWWP domain Rtt102p PF09510.10 CCC70480.1 - 3.4e-13 50.0 0.3 3.4e-13 50.0 0.3 2.2 3 0 0 3 3 3 1 Rtt102p-like transcription regulator protein RNase_T PF00929.24 CCC70481.1 - 4.5e-08 33.8 0.2 2.3e-07 31.5 0.0 2.1 2 0 0 2 2 2 1 Exonuclease ThylakoidFormat PF11264.8 CCC70481.1 - 0.046 13.4 0.0 0.15 11.7 0.0 1.8 1 0 0 1 1 1 0 Thylakoid formation protein CTP_transf_like PF01467.26 CCC70482.1 - 1.7e-10 41.2 0.0 6.9e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase-like MA3 PF02847.17 CCC70483.1 - 2.6e-21 75.7 0.5 1.4e-20 73.4 0.0 2.5 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 CCC70483.1 - 5.3e-06 26.2 4.6 1.8e-05 24.5 4.6 2.0 1 1 0 1 1 1 1 MIF4G domain Retrotrans_gag PF03732.17 CCC70483.1 - 0.11 12.8 0.2 7.8 6.8 0.0 3.0 3 0 0 3 3 3 0 Retrotransposon gag protein Glyco_hydro_17 PF00332.18 CCC70484.1 - 6.3e-11 42.4 0.8 6.3e-11 42.4 0.8 2.3 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 Sclerostin PF05463.11 CCC70484.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 Sclerostin (SOST) SR-25 PF10500.9 CCC70484.1 - 0.3 10.6 4.6 0.52 9.9 4.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.11 CCC70484.1 - 2.1 6.5 10.2 2.9 6.1 10.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_60s PF00428.19 CCC70484.1 - 2.6 8.7 16.3 4.2 8.0 14.5 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Dehydrin PF00257.19 CCC70484.1 - 4.4 7.8 10.0 1.8 9.1 7.3 1.7 2 0 0 2 2 2 0 Dehydrin G-patch PF01585.23 CCC70485.1 - 2.1e-11 43.5 0.1 4.4e-11 42.5 0.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CCC70485.1 - 0.0014 18.7 0.0 0.0014 18.7 0.0 3.5 2 1 0 2 2 1 1 G-patch domain RR_TM4-6 PF06459.12 CCC70485.1 - 0.015 15.2 22.6 0.019 14.8 22.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.14 CCC70485.1 - 0.02 13.2 26.0 0.027 12.8 26.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 CCC70485.1 - 0.034 14.3 16.9 0.052 13.7 16.9 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) GREB1 PF15782.5 CCC70485.1 - 0.11 9.6 15.7 0.13 9.3 15.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PI3K_1B_p101 PF10486.9 CCC70485.1 - 0.24 9.1 14.2 0.31 8.8 14.2 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Macoilin PF09726.9 CCC70485.1 - 0.25 9.8 20.5 0.3 9.6 20.5 1.1 1 0 0 1 1 1 0 Macoilin family Neur_chan_memb PF02932.16 CCC70485.1 - 0.28 11.2 10.4 0.38 10.8 10.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PTPRCAP PF15713.5 CCC70485.1 - 0.34 11.2 18.9 0.65 10.3 18.9 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2112 PF09885.9 CCC70485.1 - 0.35 10.9 2.4 0.73 9.9 2.0 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2112) SLC12 PF03522.15 CCC70485.1 - 0.51 9.3 20.1 0.69 8.9 20.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 CCC70485.1 - 0.9 7.6 19.8 1.1 7.3 19.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein XRN_M PF17846.1 CCC70485.1 - 0.96 8.3 13.1 1.2 8.0 13.1 1.3 1 0 0 1 1 1 0 Xrn1 helical domain VIR_N PF15912.5 CCC70485.1 - 1.4 8.4 15.2 2.1 7.9 15.2 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal ALMT PF11744.8 CCC70485.1 - 1.4 7.6 15.3 1.7 7.4 15.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 CCC70485.1 - 1.8 7.7 16.1 2.8 7.1 16.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter YL1 PF05764.13 CCC70485.1 - 2.1 8.4 47.9 3.1 7.8 47.8 1.4 1 1 0 1 1 1 0 YL1 nuclear protein SOBP PF15279.6 CCC70485.1 - 2.3 8.7 16.9 3.2 8.3 16.9 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Dsh_C PF12316.8 CCC70485.1 - 3 8.2 16.2 4.4 7.7 16.2 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CRT10 PF08728.10 CCC70485.1 - 3.7 5.6 12.4 3.8 5.6 12.4 1.1 1 0 0 1 1 1 0 CRT10 ABC_membrane PF00664.23 CCC70486.1 - 8e-78 261.9 45.8 8.4e-47 160.1 11.5 2.7 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCC70486.1 - 1.5e-44 151.9 11.0 1.2e-28 100.4 0.1 5.0 5 1 0 5 5 4 2 ABC transporter AAA_21 PF13304.6 CCC70486.1 - 4.5e-09 36.5 3.2 0.0063 16.4 0.0 4.4 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CCC70486.1 - 7.4e-09 36.4 2.5 1.7e-07 31.9 0.6 3.8 3 1 1 4 4 2 2 AAA domain AAA_15 PF13175.6 CCC70486.1 - 4.1e-08 33.3 6.9 0.0036 17.1 0.1 4.3 3 2 1 4 4 3 2 AAA ATPase domain SMC_N PF02463.19 CCC70486.1 - 9.3e-08 31.8 4.7 0.0089 15.5 0.2 4.2 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 CCC70486.1 - 4.4e-07 29.5 0.4 0.031 14.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCC70486.1 - 1.6e-05 24.9 0.6 0.054 13.4 0.0 3.1 2 1 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 CCC70486.1 - 7.9e-05 22.7 0.6 0.052 13.6 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 CCC70486.1 - 8.9e-05 22.8 2.0 1.5 9.1 0.6 3.6 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 CCC70486.1 - 0.00016 20.8 0.0 0.04 13.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 CCC70486.1 - 0.00063 20.3 0.6 0.29 11.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 CCC70486.1 - 0.001 18.4 0.0 0.083 12.2 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 CCC70486.1 - 0.0015 18.1 0.6 1.6 8.2 0.0 3.0 3 0 0 3 3 3 2 P-loop containing dynein motor region IstB_IS21 PF01695.17 CCC70486.1 - 0.0017 18.1 0.1 1.2 8.8 0.0 2.9 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_30 PF13604.6 CCC70486.1 - 0.0025 17.6 0.7 1.9 8.2 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 CCC70486.1 - 0.0031 17.9 0.1 0.77 10.1 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 CCC70486.1 - 0.015 15.7 0.1 0.34 11.3 0.0 3.1 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CCC70486.1 - 0.016 15.2 0.5 0.86 9.6 0.0 3.6 4 1 0 4 4 4 0 AAA domain (dynein-related subfamily) cobW PF02492.19 CCC70486.1 - 0.019 14.6 0.4 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 CCC70486.1 - 0.023 14.9 0.5 4.3 7.6 0.1 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Vps51 PF08700.11 CCC70486.1 - 0.024 14.7 0.1 0.024 14.7 0.1 3.4 3 1 1 4 4 3 0 Vps51/Vps67 AAA_11 PF13086.6 CCC70486.1 - 0.028 14.2 0.3 0.028 14.2 0.3 3.1 3 1 0 3 3 2 0 AAA domain TsaE PF02367.17 CCC70486.1 - 0.037 14.0 0.1 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 CCC70486.1 - 0.073 13.5 0.3 22 5.5 0.0 3.4 3 0 0 3 3 3 0 RNA helicase AAA_27 PF13514.6 CCC70486.1 - 0.087 12.4 0.2 6.5 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CCC70486.1 - 0.092 12.9 0.0 12 6.1 0.1 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 CCC70486.1 - 0.12 12.5 0.1 0.12 12.5 0.1 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain AAA_28 PF13521.6 CCC70486.1 - 0.13 12.5 0.4 4.7 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 CCC70486.1 - 0.17 11.5 0.0 6.8 6.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 CCC70486.1 - 0.17 11.5 0.1 5.5 6.6 0.1 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 CCC70486.1 - 0.22 11.6 8.6 5.1 7.1 0.1 3.9 4 0 0 4 4 4 0 Dynamin family PduV-EutP PF10662.9 CCC70486.1 - 0.29 10.9 2.5 8.3 6.2 0.0 3.6 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 CCC70486.1 - 1.4 8.7 4.4 13 5.5 0.0 3.4 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Glyco_hydro_17 PF00332.18 CCC70487.1 - 2.5e-94 316.4 3.6 3e-94 316.2 3.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 SURF4 PF02077.15 CCC70488.1 - 9.3e-97 323.8 9.1 1.1e-96 323.6 9.1 1.0 1 0 0 1 1 1 1 SURF4 family DUF2564 PF10819.8 CCC70488.1 - 0.15 12.5 0.2 0.25 11.8 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2564) MerC PF03203.14 CCC70488.1 - 0.25 11.8 10.6 1.1 9.7 1.1 2.5 2 1 0 2 2 2 0 MerC mercury resistance protein S_4TM PF18159.1 CCC70488.1 - 0.26 10.6 2.0 8.5 5.6 0.0 2.3 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain DoxX PF07681.12 CCC70488.1 - 3.1 8.5 13.5 2.7 8.6 2.9 3.0 2 1 1 3 3 3 0 DoxX RAC_head PF16717.5 CCC70489.1 - 1.4e-19 70.9 3.8 1.4e-19 70.9 3.8 3.2 2 1 0 2 2 2 1 Ribosome-associated complex head domain DnaJ PF00226.31 CCC70489.1 - 1.5e-15 57.0 0.1 4.8e-15 55.4 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain DEPP PF15343.6 CCC70489.1 - 0.6 10.2 7.0 1.4 9.0 7.0 1.6 1 0 0 1 1 1 0 Decidual protein induced by progesterone family GCD14 PF08704.10 CCC70489.1 - 0.85 9.3 0.0 0.85 9.3 0.0 2.7 2 1 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit StbA PF06406.11 CCC70490.1 - 0.11 11.7 0.8 11 5.2 0.0 2.3 2 0 0 2 2 2 0 StbA protein JAKMIP_CC3 PF16034.5 CCC70491.1 - 0.88 9.5 2.8 2.8 7.8 0.6 2.1 2 0 0 2 2 2 0 JAKMIP CC3 domain Ferrochelatase PF00762.19 CCC70492.1 - 4.8e-93 311.7 0.0 5.5e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Dimer_Tnp_hAT PF05699.14 CCC70493.1 - 5.4e-09 35.7 0.1 1.5e-08 34.3 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Flo11 PF10182.9 CCC70495.1 - 6e-69 231.0 7.3 6e-69 231.0 7.3 2.2 2 0 0 2 2 2 1 Flo11 domain WIF PF02019.18 CCC70495.1 - 0.038 13.7 0.7 0.65 9.7 0.0 2.7 3 0 0 3 3 3 0 WIF domain Sugar_tr PF00083.24 CCC70496.1 - 3.1e-166 553.7 30.2 3.6e-166 553.5 30.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC70496.1 - 2.4e-27 95.8 19.2 2.4e-27 95.8 19.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 CCC70496.1 - 0.1 12.9 4.2 0.48 10.7 0.3 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) DUF2530 PF10745.9 CCC70496.1 - 1.8 8.8 6.7 0.77 10.0 0.9 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) G6PD_C PF02781.16 CCC70497.1 - 3.7e-93 311.9 0.0 4.6e-93 311.6 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CCC70497.1 - 1.2e-51 175.9 0.0 2.1e-51 175.0 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Sir1 PF11603.8 CCC70498.1 - 5.4e-49 165.7 8.3 2.8e-27 95.6 0.2 3.6 3 0 0 3 3 3 3 Regulatory protein Sir1 CRAL_TRIO_2 PF13716.6 CCC70499.1 - 5.8e-31 107.5 0.1 1.3e-30 106.4 0.1 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.27 CCC70499.1 - 7.3e-09 35.6 1.1 1.4e-08 34.7 0.3 1.9 2 0 0 2 2 2 1 RhoGAP domain TFIID-18kDa PF02269.16 CCC70499.1 - 0.054 13.5 0.5 12 6.0 0.0 2.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Aconitase PF00330.20 CCC70500.1 - 1.3e-146 489.3 0.0 1.7e-146 488.9 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 CCC70500.1 - 1.9e-42 144.7 0.0 3.4e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 CCC70500.1 - 0.056 12.1 0.0 0.087 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) DNA_pol_phi PF04931.13 CCC70502.1 - 5.3e-233 775.5 32.1 5.3e-233 775.5 32.1 1.5 2 0 0 2 2 2 1 DNA polymerase phi UME PF08064.13 CCC70502.1 - 0.0016 18.3 0.7 0.0078 16.1 0.1 2.5 2 0 0 2 2 2 1 UME (NUC010) domain BUD22 PF09073.10 CCC70502.1 - 0.013 14.9 19.2 0.037 13.4 19.2 1.8 1 0 0 1 1 1 0 BUD22 SDA1 PF05285.12 CCC70502.1 - 0.11 12.0 20.4 0.2 11.1 20.4 1.4 1 0 0 1 1 1 0 SDA1 CLASP_N PF12348.8 CCC70502.1 - 0.12 11.9 13.7 0.51 9.9 1.5 4.2 4 0 0 4 4 4 0 CLASP N terminal FWWh PF14922.6 CCC70502.1 - 1.9 8.4 6.6 0.26 11.2 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function CAF1C_H4-bd PF12265.8 CCC70503.1 - 7.8e-24 83.7 0.3 4.7e-23 81.2 0.1 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CCC70503.1 - 3e-17 62.7 2.4 0.00066 20.4 0.0 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat SUKH_6 PF14568.6 CCC70503.1 - 0.019 15.4 3.6 2.9 8.4 0.4 3.5 2 1 2 4 4 4 0 SMI1-KNR4 cell-wall PGM_PMM_I PF02878.16 CCC70504.1 - 3.6e-15 55.9 0.0 9.3e-08 31.9 0.0 2.6 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 CCC70504.1 - 1.3e-11 44.5 0.2 2.8e-11 43.4 0.2 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Rtt106_N PF18215.1 CCC70504.1 - 3.7 7.4 4.6 49 3.8 0.3 3.8 4 0 0 4 4 4 0 Histone chaperone Rtt106 N-terminal domain Mitochondr_Som1 PF11093.8 CCC70505.1 - 4.2e-13 49.1 0.1 4.9e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Peptidase_S8 PF00082.22 CCC70506.1 - 1.3e-35 123.1 5.0 3e-35 121.9 5.0 1.6 1 1 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 CCC70506.1 - 3.1e-12 47.0 1.5 3.8e-12 46.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 ABC1 PF03109.16 CCC70506.1 - 0.026 14.7 0.3 0.57 10.4 0.1 2.5 2 0 0 2 2 2 0 ABC1 family DAGK_cat PF00781.24 CCC70507.1 - 7.3e-26 90.3 0.0 1.3e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain tRNA-synt_1c PF00749.21 CCC70508.1 - 3.8e-113 377.5 0.0 7.7e-113 376.5 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.15 CCC70508.1 - 1e-50 171.9 1.3 1.7e-50 171.2 1.3 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 CCC70508.1 - 2.9e-31 108.7 0.1 2.8e-30 105.5 0.1 2.4 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.15 CCC70508.1 - 1.2e-16 61.4 5.9 3.4e-16 59.9 5.9 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Hyphal_reg_CWP PF11765.8 CCC70509.1 - 5.3e-11 42.0 1.7 5.3e-11 42.0 1.7 1.8 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal Ribosomal_S28e PF01200.18 CCC70510.1 - 2.6e-32 110.6 2.5 2.8e-32 110.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e S_layer_C PF05124.12 CCC70510.1 - 0.16 11.9 0.0 0.16 11.9 0.0 1.1 1 0 0 1 1 1 0 S-layer like family, C-terminal region PIN_4 PF13638.6 CCC70511.1 - 8.8e-32 110.1 0.7 1.3e-31 109.5 0.1 1.6 2 0 0 2 2 2 1 PIN domain PIN_9 PF18477.1 CCC70511.1 - 0.0027 18.0 0.3 0.13 12.6 0.1 2.8 2 1 0 2 2 2 1 PIN like domain PIN_12 PF16289.5 CCC70511.1 - 0.025 15.1 0.3 0.25 11.8 0.0 2.4 2 0 0 2 2 2 0 PIN domain RHD3 PF05879.12 CCC70512.1 - 2.5e-247 822.8 27.9 3.6e-247 822.3 27.9 1.2 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 CCC70512.1 - 0.00061 19.9 0.2 0.00061 19.9 0.2 2.9 3 1 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CCC70512.1 - 0.001 19.2 0.0 0.001 19.2 0.0 3.5 3 1 0 3 3 3 1 Dynamin family SecA_SW PF07516.13 CCC70512.1 - 0.0077 16.3 13.3 2.1 8.4 13.3 3.1 1 1 0 1 1 1 1 SecA Wing and Scaffold domain DUF2254 PF10011.9 CCC70512.1 - 0.0097 14.8 0.1 0.032 13.1 0.0 1.8 2 0 0 2 2 2 1 Predicted membrane protein (DUF2254) Roc PF08477.13 CCC70512.1 - 0.061 13.5 0.2 0.21 11.8 0.2 2.0 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 CCC70512.1 - 0.1 13.1 1.3 0.79 10.2 0.0 2.6 2 0 0 2 2 2 0 ABC transporter YbfN PF13982.6 CCC70512.1 - 0.13 12.5 0.1 4.3 7.7 0.0 2.6 2 0 0 2 2 2 0 YbfN-like lipoprotein DUF410 PF04190.13 CCC70513.1 - 7.2e-81 271.7 2.3 8.9e-81 271.4 2.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF2802 PF10975.8 CCC70513.1 - 0.022 14.8 0.1 0.049 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) NUDIX PF00293.28 CCC70514.1 - 9.9e-19 67.7 0.2 1.2e-18 67.4 0.2 1.1 1 0 0 1 1 1 1 NUDIX domain Zn_clus PF00172.18 CCC70515.1 - 2.1e-08 34.2 7.8 3.9e-08 33.3 7.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SMODS PF18144.1 CCC70515.1 - 0.059 13.5 0.3 0.17 12.0 0.1 1.9 2 0 0 2 2 2 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain DcpS PF05652.12 CCC70516.1 - 9.8e-38 129.2 0.2 2e-37 128.2 0.2 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.8 CCC70516.1 - 3.5e-32 111.3 2.3 8.7e-32 110.0 0.3 2.2 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 CCC70516.1 - 0.07 13.9 0.4 0.47 11.2 0.1 2.5 3 0 0 3 3 3 0 HIT domain Med4 PF10018.9 CCC70517.1 - 1.1e-34 119.8 2.1 1.1e-34 119.8 2.1 1.7 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 MBOAT PF03062.19 CCC70518.1 - 9.5e-69 232.4 11.8 2.1e-68 231.2 11.8 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ferrochelatase PF00762.19 CCC70519.1 - 4.8e-93 311.7 0.0 5.5e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CBM_21 PF03370.13 CCC70520.1 - 2.4e-25 88.9 7.6 2.4e-25 88.9 7.6 3.3 2 0 0 2 2 2 1 Carbohydrate/starch-binding module (family 21) CBM53 PF16760.5 CCC70520.1 - 0.0073 16.9 7.4 0.0073 16.9 7.4 3.4 2 1 0 2 2 2 1 Starch/carbohydrate-binding module (family 53) Fungal_trans PF04082.18 CCC70521.1 - 8.7e-19 67.6 2.2 8.7e-19 67.6 2.2 2.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC70521.1 - 1.7e-05 24.9 10.8 4.6e-05 23.5 10.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1840 PF08895.11 CCC70521.1 - 3.1 8.2 5.2 0.95 9.8 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) ECH_1 PF00378.20 CCC70522.1 - 4.2e-18 65.6 0.0 8.7e-18 64.5 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 CCC70522.1 - 1.5e-09 37.8 0.0 1.9e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Init_tRNA_PT PF04179.12 CCC70522.1 - 0.047 14.0 0.2 0.21 11.9 0.2 2.0 1 1 0 1 1 1 0 Rit1 DUSP-like domain PhosphMutase PF10143.9 CCC70522.1 - 0.15 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase WH1 PF00568.23 CCC70523.1 - 7.6e-36 122.4 0.0 1.2e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 CCC70523.1 - 1.7e-06 27.6 1.5 3.4e-06 26.7 1.5 1.5 1 0 0 1 1 1 1 WH2 motif 30K_MP_C_Ter PF11330.8 CCC70523.1 - 0.3 10.4 2.6 0.85 8.9 0.2 2.4 2 0 0 2 2 2 0 C-Terminal of 30K viral movement proteins Ribosomal_S30 PF04758.14 CCC70524.1 - 1.3e-29 102.1 6.4 1.5e-29 102.0 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 ABC2_membrane PF01061.24 CCC70525.1 - 5e-80 267.8 51.9 8.3e-42 143.0 23.6 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 CCC70525.1 - 1.8e-38 132.2 0.0 4.2e-18 66.2 0.0 3.6 4 0 0 4 4 4 2 ABC transporter PDR_CDR PF06422.12 CCC70525.1 - 1.4e-33 114.7 5.9 2e-29 101.3 0.1 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 CCC70525.1 - 2.8e-18 66.3 0.0 5.9e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_25 PF13481.6 CCC70525.1 - 2.1e-07 30.7 0.1 1.6e-05 24.6 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CCC70525.1 - 1e-06 29.2 0.1 0.00024 21.5 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain RsgA_GTPase PF03193.16 CCC70525.1 - 6.5e-05 22.9 0.1 0.0024 17.8 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_29 PF13555.6 CCC70525.1 - 0.00012 21.7 2.4 0.0075 16.0 0.2 3.3 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_18 PF13238.6 CCC70525.1 - 0.00021 21.8 0.0 0.055 14.0 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 CCC70525.1 - 0.00026 21.2 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCC70525.1 - 0.00032 20.7 0.5 0.36 10.7 0.0 2.9 3 0 0 3 3 3 2 NACHT domain AAA_21 PF13304.6 CCC70525.1 - 0.00035 20.5 0.0 0.16 11.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 CCC70525.1 - 0.001 18.6 0.1 0.082 12.3 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 CCC70525.1 - 0.002 18.4 0.5 0.49 10.7 0.1 3.1 3 0 0 3 3 2 1 AAA domain AAA_23 PF13476.6 CCC70525.1 - 0.0044 17.6 0.0 0.028 14.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CCC70525.1 - 0.0062 16.8 0.2 0.21 11.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain OCD_Mu_crystall PF02423.15 CCC70525.1 - 0.02 13.8 0.0 0.46 9.4 0.0 2.3 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family DnaB_C PF03796.15 CCC70525.1 - 0.028 13.8 0.0 0.99 8.7 0.0 2.4 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain cobW PF02492.19 CCC70525.1 - 0.029 13.9 2.4 4 7.0 0.4 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 CCC70525.1 - 0.035 13.8 0.5 4.9 6.8 0.3 2.4 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 CCC70525.1 - 0.072 11.7 0.0 44 2.5 0.0 3.7 4 0 0 4 4 4 0 AAA domain AAA PF00004.29 CCC70525.1 - 0.085 13.3 0.0 21 5.5 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 CCC70525.1 - 0.09 12.8 0.4 1 9.4 0.1 2.6 3 0 0 3 3 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 CCC70525.1 - 0.1 11.7 0.3 5.8 6.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_17 PF13207.6 CCC70525.1 - 0.2 12.1 0.1 5.1 7.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain 4F5 PF04419.14 CCC70525.1 - 0.79 10.6 3.5 2.1 9.3 3.5 1.7 1 0 0 1 1 1 0 4F5 protein family Aminotran_5 PF00266.19 CCC70526.1 - 2.6e-37 128.6 0.0 4.5e-37 127.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V IF-2B PF01008.17 CCC70527.1 - 1.2e-85 287.1 0.0 2.3e-85 286.3 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family Ras PF00071.22 CCC70528.1 - 4.1e-50 169.5 0.0 5e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC70528.1 - 1.8e-30 105.6 0.1 4.8e-30 104.3 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC70528.1 - 3.4e-11 42.9 0.0 4.7e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 CCC70528.1 - 0.0008 19.8 0.2 0.008 16.6 0.2 2.2 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 CCC70528.1 - 0.0022 18.0 0.0 0.005 16.9 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 CCC70528.1 - 0.0045 16.4 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCC70528.1 - 0.0071 15.9 0.2 0.036 13.6 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 CCC70528.1 - 0.0074 15.5 1.4 0.8 8.8 0.1 2.7 2 1 1 3 3 3 1 G-protein alpha subunit Pox_A32 PF04665.12 CCC70528.1 - 0.018 14.5 0.1 0.033 13.6 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RsgA_GTPase PF03193.16 CCC70528.1 - 0.021 14.7 0.0 6.7 6.6 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 CCC70528.1 - 0.031 13.8 0.1 0.055 13.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region SRPRB PF09439.10 CCC70528.1 - 0.043 13.2 0.0 0.073 12.5 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 CCC70528.1 - 0.074 12.8 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 CCC70528.1 - 0.082 12.9 0.1 0.21 11.6 0.1 1.6 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 CCC70528.1 - 0.1 12.8 0.5 0.22 11.7 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 CCC70528.1 - 0.13 12.6 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ATP_sub_h PF10775.9 CCC70529.1 - 5.7e-20 71.1 0.1 9.1e-20 70.4 0.1 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h GTP_EFTU PF00009.27 CCC70530.1 - 4.2e-59 199.4 0.3 5.7e-59 198.9 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCC70530.1 - 2.3e-27 95.5 0.1 4.4e-27 94.6 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCC70530.1 - 2.9e-21 75.6 1.1 8.4e-21 74.2 1.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCC70530.1 - 2.6e-05 24.3 0.1 5.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCC70530.1 - 0.015 15.2 0.2 0.043 13.7 0.1 1.8 1 1 1 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 CCC70530.1 - 0.023 14.4 0.2 7.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 CCC70530.1 - 0.037 13.6 0.8 0.09 12.4 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF1708 PF08101.11 CCC70531.1 - 1.1e-143 479.6 10.6 1.1e-143 479.6 10.6 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF1708) RhoGAP PF00620.27 CCC70531.1 - 0.012 15.4 0.2 0.035 13.9 0.0 1.8 2 0 0 2 2 2 0 RhoGAP domain eIF3g PF12353.8 CCC70532.1 - 0.0042 17.5 0.9 0.0049 17.2 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G PFK PF00365.20 CCC70533.1 - 8.3e-185 612.7 3.8 5.4e-106 354.1 0.4 2.1 2 0 0 2 2 2 2 Phosphofructokinase Pfk_N PF18468.1 CCC70533.1 - 7.7e-28 96.8 0.2 2.1e-27 95.4 0.2 1.8 1 0 0 1 1 1 1 Phosphofructokinase N-terminal domain yeast DAGK_cat PF00781.24 CCC70533.1 - 0.011 15.4 0.1 0.036 13.7 0.1 1.9 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain Ribosomal_S11 PF00411.19 CCC70533.1 - 0.64 10.4 4.0 0.89 10.0 0.9 2.9 4 1 0 4 4 4 0 Ribosomal protein S11 Hyphal_reg_CWP PF11765.8 CCC70534.1 - 0.0002 20.4 0.0 0.00049 19.1 0.0 1.6 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal DUF3519 PF12033.8 CCC70535.1 - 0.12 12.8 0.0 0.32 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) Kelch_4 PF13418.6 CCC70536.1 - 7.1e-31 106.0 4.6 0.00011 22.1 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 CCC70536.1 - 2.8e-30 103.8 0.7 1.4e-05 24.9 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 CCC70536.1 - 2.7e-27 94.5 0.3 3.1e-05 24.1 0.2 5.7 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 CCC70536.1 - 3.6e-22 77.8 3.7 0.014 15.6 0.0 6.5 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.25 CCC70536.1 - 4.5e-14 51.8 2.0 0.0045 16.5 0.1 5.8 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 CCC70536.1 - 1.2e-11 44.1 3.7 0.3 11.1 0.0 6.1 6 0 0 6 6 6 4 Kelch motif HALZ PF02183.18 CCC70536.1 - 0.0026 17.9 1.8 0.0026 17.9 1.8 6.3 6 0 0 6 6 6 2 Homeobox associated leucine zipper ApoO PF09769.9 CCC70539.1 - 4e-22 78.6 0.0 6.4e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Apolipoprotein O Globin PF00042.22 CCC70540.1 - 8.3e-10 39.2 0.0 2.2e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Globin FAD_binding_6 PF00970.24 CCC70540.1 - 3.8e-08 33.6 0.0 6.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CCC70540.1 - 1.6e-07 31.9 0.0 4e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.8 CCC70540.1 - 0.0021 18.0 0.5 0.0056 16.6 0.2 1.9 2 1 0 2 2 2 1 Protoglobin DUF4071 PF13281.6 CCC70540.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) NAD_binding_6 PF08030.12 CCC70540.1 - 0.073 13.2 0.1 1.7 8.7 0.2 2.4 1 1 1 2 2 2 0 Ferric reductase NAD binding domain DUF3695 PF12494.8 CCC70540.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3695) RTT107_BRCT_6 PF16771.5 CCC70541.1 - 3.8e-32 110.8 0.0 3.8e-32 110.8 0.0 3.1 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain RTT107_BRCT_5 PF16770.5 CCC70541.1 - 3.4e-22 78.2 3.6 1.4e-20 73.0 0.0 4.3 4 0 0 4 4 4 1 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 CCC70541.1 - 9.6e-17 61.1 1.0 0.0001 22.6 0.0 5.2 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 CCC70541.1 - 8.7e-09 35.7 0.0 0.049 14.1 0.0 4.0 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CCC70541.1 - 2.8e-08 33.6 0.1 1.4e-06 28.1 0.0 3.3 3 0 0 3 3 3 1 twin BRCT domain Endotoxin_C PF03944.14 CCC70541.1 - 0.27 11.6 0.0 0.27 11.6 0.0 2.7 3 0 0 3 3 3 0 delta endotoxin Ank_2 PF12796.7 CCC70542.1 - 4.9e-39 132.8 13.8 1e-14 54.8 0.4 3.9 1 1 4 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCC70542.1 - 3.5e-23 81.7 4.3 1.9e-05 25.1 0.0 5.1 3 2 2 5 5 5 5 Ankyrin repeats (many copies) SPX PF03105.19 CCC70542.1 - 2.5e-22 80.3 20.9 1.1e-10 42.1 1.3 4.3 2 1 2 4 4 4 3 SPX domain Ank_3 PF13606.6 CCC70542.1 - 1.3e-20 71.3 5.4 0.0053 17.2 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 CCC70542.1 - 1.4e-19 69.6 7.8 0.0001 22.6 0.1 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 CCC70542.1 - 5.6e-19 68.0 8.2 8.4e-06 26.0 0.0 6.0 4 2 2 6 6 6 5 Ankyrin repeats (many copies) GDPD PF03009.17 CCC70542.1 - 2.7e-06 27.3 0.1 2e-05 24.5 0.0 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 CCC70543.1 - 1.4e-34 118.6 0.0 5.5e-10 39.7 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCC70543.1 - 3.4e-32 110.4 0.2 2e-09 37.8 0.0 5.1 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCC70543.1 - 2.7e-27 91.8 0.0 0.0035 17.7 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 CCC70543.1 - 9.4e-27 92.7 0.0 3.2e-08 33.7 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 CCC70543.1 - 7.1e-22 76.8 0.1 0.00028 21.2 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Band_7 PF01145.25 CCC70544.1 - 5e-23 82.0 0.5 7.9e-23 81.4 0.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Spo12 PF05032.12 CCC70545.1 - 4.3e-16 58.5 6.6 4.3e-16 58.5 6.6 2.0 1 1 1 2 2 2 1 Spo12 family DUF3576 PF12100.8 CCC70545.1 - 0.1 12.7 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3576) SMI1_KNR4 PF09346.10 CCC70546.1 - 1.8e-32 112.5 0.1 4e-31 108.1 0.0 3.0 1 1 2 3 3 3 1 SMI1 / KNR4 family (SUKH-1) DIE2_ALG10 PF04922.12 CCC70547.1 - 1e-111 374.0 37.4 1.2e-111 373.9 36.7 1.4 2 0 0 2 2 2 1 DIE2/ALG10 family WD40 PF00400.32 CCC70548.1 - 1.3e-14 54.3 2.8 0.025 15.4 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC70548.1 - 2.7e-10 40.4 0.5 0.12 12.7 0.1 5.4 3 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCC70548.1 - 7.4e-05 21.9 0.0 0.0067 15.4 0.0 3.0 3 0 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 CCC70548.1 - 0.00018 21.0 0.7 0.87 8.9 0.0 3.5 4 0 0 4 4 4 2 WD40-like domain BBS2_Mid PF14783.6 CCC70548.1 - 0.0034 17.4 0.1 3.2 7.8 0.0 3.8 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region ESPR PF13018.6 CCC70548.1 - 0.0073 16.1 1.3 0.14 12.0 0.2 2.9 3 0 0 3 3 3 1 Extended Signal Peptide of Type V secretion system BTHB PF18410.1 CCC70548.1 - 0.035 13.9 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Basic tilted helix bundle domain Frtz PF11768.8 CCC70548.1 - 0.043 12.1 0.0 0.25 9.6 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz GSHPx PF00255.19 CCC70549.1 - 1.9e-50 168.9 0.5 2.5e-50 168.6 0.5 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CCC70549.1 - 1.4e-05 25.0 0.1 6.6e-05 22.8 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCC70549.1 - 0.00056 19.7 0.1 0.0027 17.4 0.1 2.0 1 1 0 1 1 1 1 Redoxin Collagen PF01391.18 CCC70550.1 - 5.1e-08 32.6 52.5 5.6e-07 29.2 29.7 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) BetR PF08667.10 CCC70551.1 - 0.076 13.1 0.0 0.13 12.3 0.0 1.4 1 1 0 1 1 1 0 BetR domain Smg4_UPF3 PF03467.15 CCC70552.1 - 0.025 14.6 1.3 0.18 11.8 0.1 2.3 2 0 0 2 2 2 0 Smg-4/UPF3 family Rax2 PF12768.7 CCC70553.1 - 0.0012 18.4 1.4 0.0025 17.3 0.0 2.1 2 0 0 2 2 2 1 Cortical protein marker for cell polarity SKG6 PF08693.10 CCC70553.1 - 0.009 15.4 0.5 0.02 14.3 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain HLH PF00010.26 CCC70555.1 - 4.1e-20 71.5 0.6 8.1e-20 70.5 0.6 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MMR_HSR1_Xtn PF16897.5 CCC70556.1 - 3.5e-38 129.9 0.0 7.1e-38 128.9 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 CCC70556.1 - 6.1e-22 77.4 0.0 1.2e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 CCC70556.1 - 2.5e-20 72.7 0.1 7.4e-20 71.1 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCC70556.1 - 4.9e-10 39.2 0.1 1.4e-09 37.7 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.6 CCC70556.1 - 0.0043 17.3 0.4 0.47 10.7 0.3 2.6 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 CCC70556.1 - 0.005 16.9 0.4 4.2 7.4 0.3 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 CCC70556.1 - 0.012 14.6 0.1 0.029 13.3 0.1 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 CCC70556.1 - 0.063 12.7 0.2 1.9 7.9 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CCC70556.1 - 0.14 12.1 0.6 2.4 8.0 0.1 2.7 3 0 0 3 3 3 0 RsgA GTPase RNA_pol_Rpb1_5 PF04998.17 CCC70557.1 - 2.9e-97 325.3 7.9 3.6e-97 325.0 3.5 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 CCC70557.1 - 6.7e-71 237.9 0.3 1.8e-70 236.5 0.3 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CCC70557.1 - 2e-40 138.3 0.1 1.5e-38 132.2 0.0 3.4 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 CCC70557.1 - 3.8e-24 85.6 0.6 3.8e-24 85.6 0.6 3.9 4 1 0 4 4 4 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 CCC70557.1 - 6.3e-24 84.0 2.7 1e-23 83.3 0.0 2.9 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 FYDLN_acid PF09538.10 CCC70557.1 - 0.41 11.3 14.9 10 6.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Mis12 PF05859.12 CCC70558.1 - 4e-43 146.7 3.6 4e-43 146.7 3.6 2.1 2 1 0 2 2 2 1 Mis12 protein SWIRM PF04433.17 CCC70559.1 - 2.6e-10 40.5 0.1 2.1e-09 37.6 0.0 2.2 2 0 0 2 2 2 1 SWIRM domain bZIP_2 PF07716.15 CCC70561.1 - 7.8e-10 38.7 7.4 7.8e-10 38.7 7.4 3.1 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 CCC70561.1 - 0.00054 20.0 20.4 0.0025 17.9 14.1 3.4 3 1 1 4 4 4 2 bZIP transcription factor TSC22 PF01166.18 CCC70561.1 - 0.076 13.3 0.5 0.076 13.3 0.5 3.2 2 1 0 3 3 3 0 TSC-22/dip/bun family Complex1_49kDa PF00346.19 CCC70561.1 - 0.12 11.5 0.7 0.21 10.7 0.3 1.6 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit FlaC_arch PF05377.11 CCC70561.1 - 0.16 12.4 0.4 0.16 12.4 0.4 3.6 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Prismane PF03063.20 CCC70561.1 - 0.43 9.2 2.3 0.45 9.1 2.3 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family RRM_3 PF08777.11 CCC70561.1 - 0.46 10.5 9.1 0.45 10.6 6.8 2.0 1 1 1 2 2 2 0 RNA binding motif bZIP_Maf PF03131.17 CCC70561.1 - 0.55 10.8 14.8 0.18 12.3 12.0 1.7 2 1 0 2 2 1 0 bZIP Maf transcription factor PHM7_cyt PF14703.6 CCC70561.1 - 1.2 9.3 10.6 1.8 8.7 10.6 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Allexi_40kDa PF05549.11 CCC70561.1 - 2.8 7.4 10.4 5.8 6.3 10.3 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF4140 PF13600.6 CCC70561.1 - 8.5 6.9 9.6 1.4e+02 3.0 9.6 2.3 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) YabA PF06156.13 CCC70561.1 - 9 7.0 20.9 0.19 12.4 3.6 3.0 1 1 1 3 3 3 0 Initiation control protein YabA Mannosyl_trans3 PF11051.8 CCC70562.1 - 6.1e-77 258.7 0.1 1e-76 258.0 0.1 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative Sua5_yciO_yrdC PF01300.18 CCC70562.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 Telomere recombination ABC2_membrane PF01061.24 CCC70563.1 - 1.2e-64 217.6 64.6 3.5e-34 118.1 29.4 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 CCC70563.1 - 2.1e-27 96.3 0.0 7.8e-15 55.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCC70563.1 - 3.5e-26 90.9 17.1 4.9e-23 80.8 0.3 3.7 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CCC70563.1 - 3.1e-05 23.2 16.3 3.1e-05 23.2 16.3 4.6 4 1 1 5 5 5 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 CCC70563.1 - 4.4e-05 23.5 0.1 9.9e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 CCC70563.1 - 0.00058 19.8 2.0 0.098 12.4 0.2 2.8 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 CCC70563.1 - 0.0016 19.0 0.0 0.0053 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 CCC70563.1 - 0.0044 16.5 0.1 0.38 10.2 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 CCC70563.1 - 0.011 15.3 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 CCC70563.1 - 0.023 15.0 0.1 0.06 13.6 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CCC70563.1 - 0.03 14.7 0.1 0.062 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 CCC70563.1 - 0.04 13.7 0.3 0.13 12.0 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 CCC70563.1 - 0.067 13.3 0.1 0.56 10.3 0.1 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRP1_TIP1 PF00660.17 CCC70564.1 - 3.1e-37 126.6 1.8 6e-37 125.7 1.8 1.5 1 0 0 1 1 1 1 Seripauperin and TIP1 family DDHD PF02862.17 CCC70564.1 - 0.0018 18.5 7.0 0.0029 17.8 7.0 1.4 1 0 0 1 1 1 1 DDHD domain SOG2 PF10428.9 CCC70564.1 - 0.026 13.7 28.6 0.029 13.6 28.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 CCC70564.1 - 0.42 9.3 13.8 0.64 8.7 13.8 1.3 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 CCC70564.1 - 0.44 10.5 8.5 0.52 10.3 8.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRP-alpha_N PF04086.13 CCC70564.1 - 0.69 9.8 14.2 0.87 9.4 14.2 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SAPS PF04499.15 CCC70564.1 - 0.69 8.6 3.6 0.73 8.6 3.6 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sec3_C PF09763.9 CCC70564.1 - 0.91 7.8 5.8 0.96 7.8 5.8 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 DUF572 PF04502.13 CCC70564.1 - 1.4 8.4 12.4 1.7 8.2 12.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF812 PF05667.11 CCC70564.1 - 1.5 7.7 5.9 1.6 7.6 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) PAP1 PF08601.10 CCC70564.1 - 1.5 8.5 32.1 2 8.1 32.1 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 GREB1 PF15782.5 CCC70564.1 - 1.7 5.6 16.5 1.8 5.6 16.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Apt1 PF10351.9 CCC70564.1 - 2.9 6.7 26.2 3.8 6.3 26.2 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SLC12 PF03522.15 CCC70564.1 - 6.3 5.7 7.4 8.4 5.3 7.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SPX PF03105.19 CCC70564.1 - 8.4 6.2 26.9 11 5.9 26.9 1.1 1 0 0 1 1 1 0 SPX domain GEMIN8 PF15348.6 CCC70564.1 - 8.7 6.6 11.3 12 6.1 11.3 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 AhpC-TSA PF00578.21 CCC70565.1 - 9.6e-27 93.4 0.0 1.5e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCC70565.1 - 6.6e-17 61.6 0.0 1.1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin DUF1644 PF07800.12 CCC70565.1 - 0.0069 16.5 0.1 0.016 15.3 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1644) DUF349 PF03993.12 CCC70565.1 - 0.14 12.5 0.7 0.33 11.3 0.7 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) AAA PF00004.29 CCC70566.1 - 2e-10 41.2 0.2 1.4e-09 38.4 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 CCC70566.1 - 2.7e-07 30.7 2.3 7.4e-06 26.0 0.1 3.3 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 CCC70566.1 - 7e-05 23.3 0.0 0.0002 21.8 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCC70566.1 - 0.00014 22.1 0.0 0.0046 17.2 0.0 2.9 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 CCC70566.1 - 0.00054 19.7 0.0 0.0013 18.5 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 CCC70566.1 - 0.00058 20.4 0.3 0.11 13.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_assoc_2 PF16193.5 CCC70566.1 - 0.00066 20.0 0.0 0.0022 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA_14 PF13173.6 CCC70566.1 - 0.0023 18.0 0.0 0.0023 18.0 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 CCC70566.1 - 0.0089 16.2 0.0 0.027 14.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain XPC-binding PF09280.11 CCC70566.1 - 0.0092 15.7 0.1 0.057 13.2 0.0 2.4 2 0 0 2 2 2 1 XPC-binding domain RNA_helicase PF00910.22 CCC70566.1 - 0.018 15.4 0.0 0.09 13.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase IPT PF01745.16 CCC70566.1 - 0.03 13.7 0.1 0.093 12.1 0.0 1.8 2 0 0 2 2 2 0 Isopentenyl transferase AAA_5 PF07728.14 CCC70566.1 - 0.077 13.0 0.0 0.33 10.9 0.0 2.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 CCC70566.1 - 0.078 12.8 0.2 0.078 12.8 0.2 2.8 3 1 0 3 3 3 0 AAA domain Cytidylate_kin PF02224.18 CCC70566.1 - 0.37 10.5 2.6 2.3 7.9 0.0 2.8 3 0 0 3 3 3 0 Cytidylate kinase Hydin_ADK PF17213.3 CCC70566.1 - 1.3 9.3 4.6 0.82 9.9 0.1 2.5 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain CRAL_TRIO PF00650.20 CCC70567.1 - 7.1e-35 120.1 0.0 8.7e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 CCC70567.1 - 0.01 16.0 0.0 0.016 15.4 0.0 1.2 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain DUF1769 PF08588.10 CCC70567.1 - 0.086 13.1 0.1 0.26 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1769) Cnd1 PF12717.7 CCC70568.1 - 6.5e-06 26.3 10.8 0.001 19.2 1.8 5.2 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 CCC70568.1 - 0.0051 17.0 0.0 1.3e+02 3.2 0.0 5.4 6 0 0 6 6 6 0 HEAT repeat MSA-2c PF12238.8 CCC70568.1 - 0.045 13.8 1.9 7.6 6.5 0.2 2.8 2 0 0 2 2 2 0 Merozoite surface antigen 2c PHD PF00628.29 CCC70569.1 - 2.1e-13 49.9 19.1 7.1e-10 38.6 8.5 2.9 2 1 1 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.6 CCC70569.1 - 0.0063 16.8 5.9 0.06 13.6 1.0 2.6 2 0 0 2 2 2 2 PHD-like zinc-binding domain zf-RanBP PF00641.18 CCC70569.1 - 0.1 12.0 2.2 0.37 10.1 0.4 2.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Zn_ribbon_2 PF12674.7 CCC70569.1 - 0.17 12.5 4.3 0.17 12.6 1.1 2.6 2 0 0 2 2 2 0 Putative zinc ribbon domain dsDNA_bind PF01984.20 CCC70570.1 - 4.9e-28 97.6 0.3 5.8e-28 97.4 0.3 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Cyt-b5 PF00173.28 CCC70571.1 - 1.5e-18 66.7 0.0 2.4e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HMG_box PF00505.19 CCC70572.1 - 1.8e-36 124.3 12.1 2.4e-19 69.5 5.4 2.5 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.10 CCC70572.1 - 5.2e-23 81.4 4.2 1.6e-13 51.0 4.1 2.2 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.12 CCC70572.1 - 1.4e-10 40.9 0.0 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 2 CHDNT (NUC034) domain LPD11 PF18824.1 CCC70572.1 - 0.058 13.5 0.8 0.1 12.7 0.8 1.4 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 AAA_23 PF13476.6 CCC70572.1 - 0.11 13.0 2.6 0.18 12.3 2.6 1.3 1 0 0 1 1 1 0 AAA domain Cg6151-P PF10233.9 CCC70573.1 - 2.4e-38 130.9 15.9 2.9e-38 130.6 15.9 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P IncE PF17627.2 CCC70573.1 - 5.5 7.0 10.5 2.6 8.0 2.0 2.2 2 0 0 2 2 2 0 Inclusion membrane protein E zf-C2H2 PF00096.26 CCC70574.1 - 1.9e-05 24.8 14.2 4.2e-05 23.8 3.5 3.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC70574.1 - 0.0017 19.0 3.2 0.0017 19.0 3.2 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-MYST PF17772.1 CCC70574.1 - 0.0018 17.9 4.2 0.23 11.1 0.2 2.7 1 1 1 2 2 2 2 MYST family zinc finger domain zf-Di19 PF05605.12 CCC70574.1 - 0.0035 17.6 3.8 0.011 16.0 3.8 1.9 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.8 CCC70574.1 - 0.042 14.2 1.4 0.16 12.3 1.4 2.1 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CCC70574.1 - 0.28 11.5 6.0 2.9 8.3 1.4 2.7 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.15 CCC70574.1 - 2.9 8.0 12.9 0.84 9.7 3.3 2.7 1 1 1 2 2 2 0 BED zinc finger zf-met PF12874.7 CCC70574.1 - 3.9 8.0 7.5 5.3 7.6 1.9 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CCC70575.1 - 3.7e-05 23.9 11.0 0.00053 20.3 1.0 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC70575.1 - 0.00065 20.3 7.7 0.014 16.2 0.8 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCC70575.1 - 0.0013 19.1 0.1 0.0013 19.1 0.1 3.0 3 0 0 3 3 3 1 Zinc-finger double domain SR-25 PF10500.9 CCC70575.1 - 0.0014 18.3 10.4 0.0014 18.3 10.4 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein zf-C2H2_6 PF13912.6 CCC70575.1 - 0.0045 17.0 0.2 0.011 15.7 0.2 1.7 1 0 0 1 1 1 1 C2H2-type zinc finger DUF2180 PF09947.9 CCC70575.1 - 0.029 14.3 0.1 0.062 13.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) zf-met PF12874.7 CCC70575.1 - 0.1 13.0 4.1 0.34 11.4 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type FOXP-CC PF16159.5 CCC70575.1 - 0.12 13.0 0.2 0.12 13.0 0.2 2.0 2 0 0 2 2 2 0 FOXP coiled-coil domain IMUP PF15761.5 CCC70575.1 - 0.17 12.6 10.1 0.38 11.4 10.1 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein zf-H2C2_5 PF13909.6 CCC70575.1 - 2.6 7.9 8.9 6.4 6.6 0.5 2.8 2 1 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.15 CCC70575.1 - 3.1 7.9 10.4 1.4 9.0 3.8 2.7 1 1 1 2 2 2 0 BED zinc finger zf-C2H2 PF00096.26 CCC70576.1 - 3e-07 30.5 8.2 0.00063 20.1 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC70576.1 - 0.00011 22.5 0.2 0.00011 22.5 0.2 3.7 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC70576.1 - 0.0023 18.6 8.8 0.022 15.5 0.7 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_5 PF13909.6 CCC70576.1 - 0.0041 16.8 9.5 0.32 10.8 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc-finger domain GAGA PF09237.11 CCC70576.1 - 0.0058 16.4 0.3 0.015 15.1 0.3 1.7 1 0 0 1 1 1 1 GAGA factor zf-met PF12874.7 CCC70576.1 - 0.007 16.7 4.7 0.012 15.9 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type FOXP-CC PF16159.5 CCC70576.1 - 0.016 15.8 1.4 0.097 13.3 0.3 2.4 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_jaz PF12171.8 CCC70576.1 - 0.054 13.8 1.2 0.3 11.4 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Mito_carr PF00153.27 CCC70578.1 - 2.4e-59 197.3 1.3 2.4e-21 75.5 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L14e PF01929.17 CCC70579.1 - 3.2e-32 110.8 1.2 5.9e-32 110.0 1.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 CCC70579.1 - 5.6e-05 23.0 0.2 0.00012 21.9 0.2 1.5 1 0 0 1 1 1 1 KOW motif Oxysterol_BP PF01237.18 CCC70580.1 - 2.2e-81 273.6 0.2 2.2e-79 267.0 0.2 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein TRAM_LAG1_CLN8 PF03798.16 CCC70581.1 - 5.6e-38 130.7 25.9 5.6e-38 130.7 25.9 2.5 3 0 0 3 3 3 2 TLC domain TRAM1 PF08390.11 CCC70581.1 - 1.1e-21 76.3 1.3 1.1e-21 76.3 1.3 2.7 2 0 0 2 2 2 1 TRAM1-like protein DUF4834 PF16118.5 CCC70581.1 - 5.8 7.9 6.4 6.2 7.9 0.0 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4834) PQ-loop PF04193.14 CCC70582.1 - 3.4e-08 33.2 7.8 8.9e-08 31.8 2.6 4.2 4 1 1 5 5 5 2 PQ loop repeat ARD PF03079.14 CCC70583.1 - 2e-42 145.0 0.3 2.4e-42 144.8 0.3 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 CCC70583.1 - 2.1e-10 40.2 0.0 3.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 CCC70583.1 - 3.1e-06 27.1 0.0 4.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 CCC70583.1 - 0.00024 20.7 0.0 0.00031 20.4 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.6 CCC70583.1 - 0.026 14.3 0.0 0.062 13.0 0.0 1.5 1 1 0 1 1 1 0 Cupin-like domain JmjC PF02373.22 CCC70583.1 - 0.088 13.2 0.1 0.4 11.1 0.0 1.9 1 1 1 2 2 2 0 JmjC domain, hydroxylase bZIP_1 PF00170.21 CCC70584.1 - 3.4e-05 23.9 11.9 3.4e-05 23.9 11.9 3.2 2 1 1 3 3 3 1 bZIP transcription factor Hap4_Hap_bind PF10297.9 CCC70584.1 - 0.0039 17.3 1.3 0.0039 17.3 1.3 2.5 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 THOC2_N PF16134.5 CCC70584.1 - 0.0045 15.7 0.1 0.0069 15.1 0.1 1.2 1 0 0 1 1 1 1 THO complex subunit 2 N-terminus bZIP_Maf PF03131.17 CCC70584.1 - 0.034 14.7 10.1 0.11 13.0 10.1 1.9 1 0 0 1 1 1 0 bZIP Maf transcription factor NBP1 PF08537.10 CCC70584.1 - 0.038 13.4 10.4 0.1 12.0 10.4 1.7 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Exonuc_VII_L PF02601.15 CCC70584.1 - 0.93 9.0 4.9 0.63 9.5 3.4 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit SlyX PF04102.12 CCC70584.1 - 1.3 9.7 5.8 0.89 10.2 2.9 2.2 2 0 0 2 2 2 0 SlyX SKA1 PF07160.12 CCC70584.1 - 6.8 6.5 14.3 0.6 9.9 6.0 2.3 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 DUF1746 PF08508.10 CCC70585.1 - 0.0064 16.8 7.1 0.013 15.8 6.3 2.0 2 1 0 2 2 2 1 Fungal domain of unknown function (DUF1746) DUF5083 PF16890.5 CCC70585.1 - 0.011 15.5 4.3 0.02 14.6 3.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5083) Baculo_RING PF05883.11 CCC70585.1 - 0.075 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain Rpr2 PF04032.16 CCC70586.1 - 2.7e-19 69.2 2.9 4.3e-19 68.6 2.9 1.3 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Proteasome PF00227.26 CCC70587.1 - 2.9e-56 190.0 0.0 3.8e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCC70587.1 - 2.6e-13 49.4 0.2 5.8e-13 48.2 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature RNase_P_Rpp14 PF01900.19 CCC70588.1 - 5.2e-33 113.4 0.1 6.8e-33 113.0 0.1 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Cellulase PF00150.18 CCC70589.1 - 3.7e-15 56.1 0.3 5.4e-10 39.2 0.2 3.1 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 CCC70589.1 - 1.3e-11 44.9 0.0 3e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_14 PF01373.17 CCC70589.1 - 0.0064 15.5 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Glyco_hydro_42 PF02449.15 CCC70589.1 - 0.0074 15.7 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 CCC70589.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DNA_primase_S PF01896.19 CCC70590.1 - 6.4e-65 218.5 0.6 9.5e-65 217.9 0.6 1.3 1 0 0 1 1 1 1 DNA primase small subunit Zn_clus PF00172.18 CCC70591.1 - 6.7e-08 32.5 7.3 1.3e-07 31.6 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cas_Cas5d PF09704.10 CCC70591.1 - 0.033 14.1 0.6 8.8 6.1 0.1 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas5) IL3 PF02059.15 CCC70592.1 - 0.0096 16.0 2.5 1.9 8.6 0.2 3.6 3 0 0 3 3 3 2 Interleukin-3 AMPKBI PF04739.15 CCC70593.1 - 2.6e-20 72.5 3.9 2.6e-20 72.4 0.9 2.6 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain AMPK1_CBM PF16561.5 CCC70593.1 - 9.2e-09 35.4 0.0 2.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase bZIP_1 PF00170.21 CCC70594.1 - 2.7e-06 27.4 7.6 7.4e-06 26.0 7.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor PAP1 PF08601.10 CCC70594.1 - 0.00064 19.6 39.9 0.5 10.0 39.9 3.5 1 1 0 1 1 1 1 Transcription factor PAP1 bZIP_2 PF07716.15 CCC70594.1 - 0.0023 17.9 9.7 0.0057 16.7 9.7 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Transpos_assoc PF13963.6 CCC70594.1 - 0.072 13.4 0.3 0.23 11.8 0.3 1.8 1 0 0 1 1 1 0 Transposase-associated domain bZIP_Maf PF03131.17 CCC70594.1 - 1.6 9.3 10.5 0.05 14.1 3.6 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Dynein_light PF01221.18 CCC70595.1 - 6.6e-33 112.9 0.0 7.2e-33 112.8 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 CCC70595.1 - 0.034 14.8 0.0 0.043 14.5 0.0 1.2 1 0 0 1 1 1 0 Ground-like domain Rpn9_C PF18261.1 CCC70596.1 - 3.4e-18 64.9 3.2 3.4e-18 64.9 3.2 2.1 2 0 0 2 2 2 1 Rpn9 C-terminal helix PCI PF01399.27 CCC70596.1 - 6.5e-13 49.1 2.9 7.4e-13 48.9 0.5 2.2 2 0 0 2 2 2 1 PCI domain CSN8_PSD8_EIF3K PF10075.9 CCC70596.1 - 0.00051 20.1 2.8 0.0049 16.8 0.3 2.4 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family EMP24_GP25L PF01105.24 CCC70597.1 - 1.2e-41 142.7 0.0 1.4e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 CCC70597.1 - 0.0062 14.8 0.2 0.0079 14.4 0.2 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA M16C_assoc PF08367.11 CCC70598.1 - 6.7e-73 244.9 0.8 1.1e-72 244.2 0.8 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 CCC70598.1 - 5.6e-30 104.7 0.6 4.2e-19 69.3 0.1 3.4 4 0 0 4 4 4 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 CCC70598.1 - 2e-07 31.1 0.1 1.2e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF455 PF04305.14 CCC70598.1 - 0.11 12.1 0.2 9.7 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF455) Tugs PF17840.1 CCC70598.1 - 1.4 9.2 3.4 3.1 8.1 0.9 2.5 2 0 0 2 2 2 0 Tethering Ubl4a to BAGS domain RRM_1 PF00076.22 CCC70599.1 - 1.4e-30 104.9 0.6 1.7e-17 63.0 0.3 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCC70599.1 - 0.00013 21.7 0.0 0.0045 16.8 0.0 2.1 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_5 PF13893.6 CCC70599.1 - 0.0016 18.0 0.0 0.06 12.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC70599.1 - 0.054 13.6 0.1 0.3 11.2 0.1 2.0 1 1 0 1 1 1 0 RNA recognition motif Limkain-b1 PF11608.8 CCC70599.1 - 0.12 12.5 0.0 3.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 PIG-S PF10510.9 CCC70600.1 - 1.6e-133 446.3 10.6 1.9e-133 446.0 10.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TAFII28 PF04719.14 CCC70601.1 - 1.5e-27 95.5 0.3 2.4e-23 82.0 0.0 2.6 3 0 0 3 3 3 2 hTAFII28-like protein conserved region Enkurin PF13864.6 CCC70601.1 - 0.41 11.1 4.8 0.43 11.0 0.7 2.5 2 0 0 2 2 2 0 Calmodulin-binding PBP1_TM PF14812.6 CCC70601.1 - 1.1 9.6 7.7 0.13 12.7 1.9 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LCM PF04072.14 CCC70602.1 - 9.9e-25 87.6 0.0 1.3e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase PIG-P PF08510.12 CCC70603.1 - 7.3e-30 103.4 3.2 1.1e-29 102.8 3.2 1.2 1 0 0 1 1 1 1 PIG-P CCSMST1 PF15013.6 CCC70603.1 - 0.14 12.4 0.2 0.25 11.5 0.2 1.4 1 0 0 1 1 1 0 CCSMST1 family DUF624 PF04854.14 CCC70603.1 - 2.9 8.1 6.5 0.16 12.1 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function, DUF624 EamA PF00892.20 CCC70604.1 - 1.5e-12 47.8 40.7 4.5e-06 26.9 12.8 3.3 2 1 0 2 2 2 2 EamA-like transporter family SLC35F PF06027.12 CCC70604.1 - 8.3e-06 25.5 5.2 1.6e-05 24.6 5.2 1.6 1 1 0 1 1 1 1 Solute carrier family 35 PUNUT PF16913.5 CCC70604.1 - 1.6e-05 24.3 16.6 1.6e-05 24.3 16.6 2.5 1 1 0 2 2 2 1 Purine nucleobase transmembrane transport LRS4 PF10422.9 CCC70605.1 - 2.8e-22 79.5 26.8 1.2e-19 70.9 26.8 2.4 1 1 0 1 1 1 1 Monopolin complex subunit LRS4 FlxA PF14282.6 CCC70605.1 - 0.00015 21.7 14.6 0.00015 21.7 14.6 1.8 2 0 0 2 2 2 1 FlxA-like protein PIEZO PF15917.5 CCC70605.1 - 0.0047 16.4 4.3 0.0059 16.1 4.3 1.3 1 0 0 1 1 1 1 Piezo DUF722 PF05263.11 CCC70605.1 - 0.046 13.9 2.7 0.079 13.2 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Allexi_40kDa PF05549.11 CCC70605.1 - 0.21 11.1 6.7 0.33 10.4 6.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein DOT1 PF08123.13 CCC70606.1 - 1.2e-84 282.9 0.4 2e-84 282.2 0.4 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 DUF3583 PF12126.8 CCC70606.1 - 4 6.8 13.4 6 6.2 13.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3583) Med13_N PF11597.8 CCC70607.1 - 6.8e-67 226.1 0.1 1.1e-66 225.4 0.1 1.4 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal Med13_C PF06333.12 CCC70607.1 - 2.9e-24 85.9 1.0 3.9e-16 59.2 0.0 3.3 2 1 1 3 3 3 2 Mediator complex subunit 13 C-terminal domain DUF676 PF05057.14 CCC70608.1 - 1.6e-54 184.7 0.0 2.7e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 CCC70608.1 - 4.6e-05 23.3 0.0 0.00012 21.9 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) DUF915 PF06028.11 CCC70608.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) BshC PF10079.9 CCC70608.1 - 0.059 12.1 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC Lipase PF00151.19 CCC70608.1 - 0.13 11.5 0.0 0.2 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipase DUF1353 PF07087.11 CCC70608.1 - 0.18 11.5 0.1 8.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1353) MFA1_2 PF17317.2 CCC70609.1 - 1e-15 57.1 3.3 1.1e-15 57.1 3.3 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 ECM11 PF15463.6 CCC70611.1 - 5.1e-18 65.9 2.6 1.1e-17 64.8 0.0 2.6 3 0 0 3 3 3 1 Extracellular mutant protein 11 Ribosomal_S17e PF00833.18 CCC70612.1 - 6.5e-57 190.7 0.4 7.7e-57 190.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal S17 ZZ PF00569.17 CCC70613.1 - 2.2e-15 56.2 11.4 2.6e-15 55.9 8.3 2.3 2 0 0 2 2 2 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 CCC70613.1 - 2.7e-08 33.8 0.5 6.4e-08 32.7 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain SWIRM PF04433.17 CCC70613.1 - 4.8e-06 26.8 0.0 7.1e-05 23.1 0.0 2.6 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-bind_6 PF13921.6 CCC70613.1 - 0.00011 22.4 0.0 0.00044 20.4 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Methyltransf_4 PF02390.17 CCC70613.1 - 0.079 12.4 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Putative methyltransferase U3_assoc_6 PF08640.11 CCC70614.1 - 3.9e-32 110.2 5.4 9.8e-31 105.7 1.0 3.0 2 1 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.10 CCC70614.1 - 2.5e-05 23.6 4.6 0.0076 15.4 0.6 2.9 1 1 2 3 3 3 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 CCC70614.1 - 0.00095 19.8 0.0 1.9 9.5 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCC70614.1 - 0.0068 16.7 0.8 2.9 8.5 0.2 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 CCC70614.1 - 0.041 13.6 0.0 0.54 10.0 0.1 2.4 2 0 0 2 2 2 0 TPR repeat DUF2250 PF10007.9 CCC70614.1 - 0.051 13.7 6.0 0.51 10.5 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2250) HAT PF02184.16 CCC70614.1 - 0.17 11.8 0.9 1.1 9.3 0.1 2.4 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat DUF4508 PF14969.6 CCC70614.1 - 0.21 11.8 3.8 4.5 7.6 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4508) Cas_Cas6 PF01881.16 CCC70614.1 - 0.27 11.8 3.7 9.4 6.8 0.6 2.7 2 0 0 2 2 2 0 CRISPR associated protein Cas6 Suf PF05843.14 CCC70614.1 - 1.1 9.2 15.3 0.11 12.5 5.9 3.6 2 1 0 3 3 3 0 Suppressor of forked protein (Suf) Ribosomal_S13 PF00416.22 CCC70615.1 - 1.7e-57 193.3 3.2 1.9e-57 193.1 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CCC70615.1 - 0.0017 17.2 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 CCC70615.1 - 0.097 12.9 0.3 0.51 10.6 0.1 2.2 1 1 0 2 2 2 0 Helix-hairpin-helix motif H2TH PF06831.14 CCC70615.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain Metallophos PF00149.28 CCC70616.1 - 2.4e-08 34.8 0.8 1.1e-07 32.6 0.2 2.2 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase AhpC-TSA PF00578.21 CCC70617.1 - 1.5e-32 112.1 0.0 1.5e-31 108.9 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CCC70617.1 - 1.2e-16 60.8 0.0 2.9e-16 59.5 0.0 1.5 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 CCC70617.1 - 4.8e-07 29.5 0.2 8.5e-07 28.7 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CCC70617.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 SCO1/SenC Guanylate_kin PF00625.21 CCC70618.1 - 1.5e-68 230.1 0.0 1.6e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_16 PF13191.6 CCC70618.1 - 2.1e-07 31.5 0.0 4e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 CCC70618.1 - 3.5e-07 30.5 0.0 4.6e-06 26.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.6 CCC70618.1 - 1.1e-05 25.8 0.2 0.0002 21.7 0.0 2.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 CCC70618.1 - 2.2e-05 24.5 0.0 0.00024 21.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_18 PF13238.6 CCC70618.1 - 2.9e-05 24.6 0.1 8.6e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CCC70618.1 - 5.2e-05 23.1 0.2 0.001 18.8 0.2 2.1 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 CCC70618.1 - 0.00015 22.3 0.0 0.00033 21.2 0.0 1.6 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.22 CCC70618.1 - 0.00049 20.5 0.0 0.0018 18.7 0.0 1.9 2 1 0 2 2 2 1 RNA helicase AAA_28 PF13521.6 CCC70618.1 - 0.00055 20.2 0.0 0.0011 19.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 CCC70618.1 - 0.00093 19.0 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 CCC70618.1 - 0.0014 18.0 0.0 0.0037 16.6 0.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RsgA_GTPase PF03193.16 CCC70618.1 - 0.0017 18.3 0.0 0.0028 17.6 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 CCC70618.1 - 0.0017 18.0 1.6 0.014 15.1 0.5 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 CCC70618.1 - 0.0026 18.2 0.3 0.011 16.2 0.3 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 CCC70618.1 - 0.003 17.6 0.0 0.0068 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 CCC70618.1 - 0.0077 16.2 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_2 PF07724.14 CCC70618.1 - 0.009 16.1 0.1 0.47 10.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Viral_helicase1 PF01443.18 CCC70618.1 - 0.01 15.6 0.0 0.036 13.8 0.0 1.8 1 1 1 2 2 2 0 Viral (Superfamily 1) RNA helicase T2SSE PF00437.20 CCC70618.1 - 0.011 14.9 0.5 0.02 13.9 0.1 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ATPase_2 PF01637.18 CCC70618.1 - 0.012 15.6 0.3 0.026 14.4 0.3 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 CCC70618.1 - 0.013 15.5 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 CCC70618.1 - 0.015 15.6 0.1 0.34 11.2 0.0 2.4 3 0 0 3 3 2 0 AAA domain cobW PF02492.19 CCC70618.1 - 0.019 14.6 0.1 0.046 13.3 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 CCC70618.1 - 0.019 14.9 0.0 0.035 14.0 0.0 1.5 1 0 0 1 1 1 0 NTPase dNK PF01712.19 CCC70618.1 - 0.026 14.4 0.4 0.69 9.7 0.0 2.6 2 1 0 2 2 2 0 Deoxynucleoside kinase KAP_NTPase PF07693.14 CCC70618.1 - 0.036 13.3 0.0 0.04 13.2 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.22 CCC70618.1 - 0.044 13.0 0.0 0.075 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.6 CCC70618.1 - 0.057 13.0 0.4 0.29 10.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCC70618.1 - 0.058 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 CCC70618.1 - 0.061 13.3 0.4 0.34 10.9 0.4 2.2 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Adeno_IVa2 PF02456.15 CCC70618.1 - 0.061 12.1 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein MobB PF03205.14 CCC70618.1 - 0.078 12.9 0.0 0.22 11.4 0.0 1.8 3 0 0 3 3 1 0 Molybdopterin guanine dinucleotide synthesis protein B Roc PF08477.13 CCC70618.1 - 0.093 13.0 0.0 0.79 9.9 0.0 2.2 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_17 PF13207.6 CCC70618.1 - 0.097 13.1 0.0 0.24 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 CCC70618.1 - 0.11 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_5 PF07728.14 CCC70618.1 - 0.14 12.1 0.1 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 CCC70618.1 - 0.16 11.5 0.0 12 5.4 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_23 PF13476.6 CCC70618.1 - 0.18 12.3 4.0 0.4 11.2 4.0 1.9 1 1 0 1 1 1 0 AAA domain Na_H_Exchanger PF00999.21 CCC70619.1 - 8.3e-72 242.1 34.8 1e-71 241.8 34.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.6 CCC70619.1 - 2.3 8.1 8.4 0.34 10.8 1.1 2.8 3 0 0 3 3 3 0 Myc target protein 1 Wzy_C PF04932.15 CCC70619.1 - 4.9 6.8 0.0 4.9 6.8 0.0 3.4 3 2 0 3 3 3 0 O-Antigen ligase HECT PF00632.25 CCC70620.1 - 1.2e-92 310.7 0.0 1.2e-92 310.7 0.0 2.4 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.12 CCC70620.1 - 5.3e-53 180.7 5.9 1e-51 176.5 2.7 3.0 2 1 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF913 PF06025.12 CCC70620.1 - 2.2e-47 161.8 4.8 5.2e-45 154.0 0.1 3.5 3 0 0 3 3 3 2 Domain of Unknown Function (DUF913) UBM PF14377.6 CCC70620.1 - 7.7e-14 50.6 1.4 2.6e-08 33.0 0.1 3.0 2 0 0 2 2 2 2 Ubiquitin binding region PRONE PF03759.13 CCC70620.1 - 0.014 14.2 0.3 0.032 13.1 0.3 1.5 1 0 0 1 1 1 0 PRONE (Plant-specific Rop nucleotide exchanger) FAM209 PF15206.6 CCC70620.1 - 0.038 13.8 1.7 0.088 12.6 0.0 2.3 2 0 0 2 2 2 0 FAM209 family zf-C2H2 PF00096.26 CCC70621.1 - 2.3e-08 34.0 7.5 0.00073 19.9 1.3 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC70621.1 - 1.1e-05 25.9 6.9 0.0056 17.4 1.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCC70621.1 - 0.00035 20.9 10.0 0.047 14.1 3.6 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_6 PF13912.6 CCC70621.1 - 0.00063 19.7 2.4 0.00063 19.7 2.4 2.2 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCC70621.1 - 0.01 16.1 6.7 0.013 15.8 1.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Actin_micro PF17003.5 CCC70621.1 - 0.015 14.5 3.1 0.017 14.3 3.1 1.1 1 0 0 1 1 1 0 Putative actin-like family Succ_DH_flav_C PF02910.20 CCC70621.1 - 0.02 14.9 0.1 0.031 14.3 0.1 1.3 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term zf-TRAF PF02176.18 CCC70621.1 - 0.033 14.9 5.4 0.054 14.2 5.4 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger Zf_RING PF16744.5 CCC70621.1 - 0.19 11.9 2.0 0.4 10.8 1.2 1.8 1 1 1 2 2 2 0 KIAA1045 RING finger zf-LYAR PF08790.11 CCC70621.1 - 0.3 11.0 5.6 2.2 8.3 1.0 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger DUF629 PF04780.12 CCC70621.1 - 1.2 7.6 8.6 0.092 11.3 2.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF629) MSC PF09402.10 CCC70622.1 - 1.6e-77 261.3 3.3 1.6e-77 261.3 3.3 3.1 3 0 0 3 3 3 1 Man1-Src1p-C-terminal domain HeH PF12949.7 CCC70622.1 - 1.2e-13 50.6 2.0 2.7e-13 49.4 2.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.27 CCC70622.1 - 0.082 12.7 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 SAP domain DHHC PF01529.20 CCC70623.1 - 7e-24 84.4 12.7 7e-24 84.4 12.7 2.8 2 1 0 2 2 2 1 DHHC palmitoyltransferase InPase PF18823.1 CCC70623.1 - 0.14 11.9 0.8 0.21 11.3 0.8 1.2 1 0 0 1 1 1 0 Inorganic Pyrophosphatase BAF1_ABF1 PF04684.13 CCC70624.1 - 8.7e-204 678.7 66.4 2.9e-201 670.4 66.4 2.0 1 1 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.15 CCC70624.1 - 0.037 14.0 0.3 0.085 12.9 0.3 1.5 1 0 0 1 1 1 0 MuDR family transposase XPG_N PF00752.17 CCC70625.1 - 2.9e-39 133.6 0.0 5.9e-39 132.6 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 CCC70625.1 - 3e-29 101.2 0.7 5.2e-29 100.4 0.0 1.8 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.20 CCC70625.1 - 3.6e-07 30.7 0.9 7.8e-06 26.4 0.0 2.8 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.16 CCC70625.1 - 0.00035 20.5 0.0 0.0035 17.3 0.0 2.3 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_5 PF14520.6 CCC70625.1 - 0.026 15.1 0.2 0.13 12.8 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_2 PF12826.7 CCC70625.1 - 0.091 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif Aldose_epim PF01263.20 CCC70626.1 - 2.9e-48 164.7 0.2 3.5e-48 164.4 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase zf-MYND PF01753.18 CCC70627.1 - 6.8e-07 29.3 21.5 2.3e-06 27.6 21.5 1.9 1 1 0 1 1 1 1 MYND finger Prenyltransf PF01255.19 CCC70628.1 - 3.1e-62 210.0 0.0 4.5e-62 209.5 0.0 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase WD40 PF00400.32 CCC70629.1 - 9.6e-17 61.1 19.8 3.8e-05 24.4 0.2 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC70629.1 - 2.5e-08 34.1 0.3 1.2 9.5 0.0 5.3 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 CCC70629.1 - 0.036 14.1 1.0 10 6.2 0.0 3.8 3 2 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Pkinase PF00069.25 CCC70630.1 - 3.5e-69 233.1 0.0 4.9e-69 232.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70630.1 - 2e-30 106.0 0.0 2.7e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 CCC70630.1 - 6e-10 39.7 0.2 1.6e-09 38.3 0.2 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 CCC70630.1 - 4.9e-05 22.4 0.4 7.6e-05 21.8 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 CCC70630.1 - 0.0068 15.8 0.0 0.016 14.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CCC70630.1 - 0.015 15.0 0.0 1.6 8.3 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 CCC70630.1 - 0.076 12.4 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PGM_PMM_I PF02878.16 CCC70631.1 - 6.3e-37 126.4 0.2 1.3e-36 125.4 0.2 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 CCC70631.1 - 1.1e-26 93.2 0.0 2e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 CCC70631.1 - 1.5e-13 51.2 0.0 3.3e-13 50.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 CCC70631.1 - 5.1e-07 29.8 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ku PF02735.16 CCC70632.1 - 1.5e-32 113.0 0.0 3.2e-32 111.9 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 CCC70632.1 - 1.8e-16 60.6 2.4 3.1e-16 59.8 2.4 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain TP6A_N PF04406.14 CCC70633.1 - 1.1e-12 47.7 2.0 1.2e-12 47.6 0.3 2.0 2 0 0 2 2 2 1 Type IIB DNA topoisomerase DUF436 PF04260.12 CCC70633.1 - 0.15 11.7 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF436) TPP_enzyme_N PF02776.18 CCC70634.1 - 1.6e-56 190.6 0.4 1.7e-55 187.2 0.1 2.7 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 CCC70634.1 - 2.2e-49 167.2 0.3 4e-48 163.1 0.0 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCC70634.1 - 2.1e-41 140.9 0.5 1.2e-40 138.4 0.3 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Aldedh PF00171.22 CCC70635.1 - 9.8e-79 265.0 0.0 1.2e-78 264.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3447 PF11929.8 CCC70635.1 - 0.0085 16.0 0.7 0.035 14.1 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Cys_Met_Meta_PP PF01053.20 CCC70636.1 - 1.4e-145 484.7 0.0 1.6e-145 484.5 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 CCC70636.1 - 1e-05 24.3 0.0 1.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 CCC70636.1 - 0.00015 21.1 0.0 0.00023 20.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CCC70636.1 - 0.0073 15.3 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 CCC70636.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Ribosomal_S19 PF00203.21 CCC70637.1 - 3e-33 113.5 0.0 6.9e-33 112.4 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein S19 Sds3 PF08598.11 CCC70638.1 - 4.5e-51 173.9 4.5 4.5e-51 173.9 4.5 2.6 2 1 0 2 2 2 1 Sds3-like SNARE PF05739.19 CCC70639.1 - 5.2e-08 32.8 0.0 9.6e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 CCC70639.1 - 0.0013 18.6 4.9 0.0051 16.6 4.9 2.0 1 1 0 1 1 1 1 Membrane fusion protein Use1 DUF5401 PF17380.2 CCC70639.1 - 0.055 11.5 0.0 0.079 11.0 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) HhH-GPD PF00730.25 CCC70640.1 - 7.7e-26 90.7 0.0 1.6e-25 89.6 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 CCC70640.1 - 7e-05 22.5 0.0 7e-05 22.5 0.0 3.0 5 0 0 5 5 5 1 Helix-hairpin-helix motif HEAT PF02985.22 CCC70641.1 - 3.5e-38 126.3 12.7 0.023 14.9 0.0 13.1 13 0 0 13 13 13 11 HEAT repeat HEAT_2 PF13646.6 CCC70641.1 - 5.3e-30 103.7 3.5 1.1e-07 32.1 0.0 8.4 3 3 5 8 8 8 6 HEAT repeats Vac14_Fab1_bd PF12755.7 CCC70641.1 - 2.1e-13 50.7 5.9 0.024 15.2 0.0 8.5 4 3 6 10 10 10 5 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 CCC70641.1 - 0.00018 21.6 13.8 0.15 12.0 1.4 6.0 2 2 3 5 5 5 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CCC70641.1 - 0.0013 19.1 11.9 27 5.4 0.0 8.2 9 1 1 10 10 10 0 HEAT-like repeat Arm PF00514.23 CCC70641.1 - 0.0034 17.4 4.2 3.4 7.8 0.0 6.1 7 0 0 7 7 7 1 Armadillo/beta-catenin-like repeat DNA_alkylation PF08713.11 CCC70641.1 - 0.026 14.2 0.1 1.7 8.3 0.0 3.5 4 1 1 5 5 5 0 DNA alkylation repair enzyme M11L PF11099.8 CCC70641.1 - 0.27 11.5 7.9 5.3 7.3 0.2 4.0 2 1 0 3 3 3 0 Apoptosis regulator M11L like API5 PF05918.11 CCC70641.1 - 0.47 9.2 12.7 0.81 8.4 0.4 4.6 5 1 1 6 6 6 0 Apoptosis inhibitory protein 5 (API5) Pkinase PF00069.25 CCC70642.1 - 3.1e-63 213.6 0.6 4.7e-63 213.0 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70642.1 - 4.9e-22 78.5 0.0 9.1e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC70642.1 - 4.8e-09 35.9 0.0 8.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 CCC70642.1 - 0.0025 16.9 1.3 0.086 11.9 0.1 2.6 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 CCC70642.1 - 0.0042 15.9 0.0 0.01 14.6 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 CCC70642.1 - 0.0063 16.5 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAS_9 PF13426.7 CCC70642.1 - 0.028 14.7 0.0 0.36 11.1 0.0 2.5 2 0 0 2 2 2 0 PAS domain Kdo PF06293.14 CCC70642.1 - 0.03 13.7 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CCC70642.1 - 0.033 13.8 0.1 0.082 12.5 0.1 1.6 1 0 0 1 1 1 0 RIO1 family PAS PF00989.25 CCC70642.1 - 0.052 13.5 0.0 2.9 7.9 0.0 3.2 3 0 0 3 3 3 0 PAS fold FTA2 PF13095.6 CCC70642.1 - 0.066 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 EI24 PF07264.11 CCC70643.1 - 0.00017 21.9 18.0 0.00034 20.9 18.0 1.5 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Ycf4 PF02392.16 CCC70643.1 - 0.024 14.2 0.7 0.061 12.9 0.7 1.6 1 0 0 1 1 1 0 Ycf4 Gal11_ABD1 PF18535.1 CCC70644.1 - 1.4e-38 130.9 21.6 1.4e-38 130.9 21.6 6.3 5 1 1 6 6 6 1 Gal11 activator-binding domain (ABD1) Med15_fungi PF05397.12 CCC70644.1 - 2e-34 118.2 2.6 2e-34 118.2 2.6 6.4 5 1 2 7 7 7 1 Mediator complex subunit 15 KIX_2 PF16987.5 CCC70644.1 - 1.9e-18 66.2 2.3 1.9e-18 66.2 2.3 5.8 6 1 1 7 7 7 1 KIX domain PGM_PMM_II PF02879.16 CCC70644.1 - 0.15 12.7 0.0 1.6 9.4 0.0 2.7 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Hyphal_reg_CWP PF11765.8 CCC70645.1 - 6.9e-09 35.1 1.8 1.3e-08 34.2 0.2 1.9 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal SNF2_N PF00176.23 CCC70646.1 - 1.1e-55 188.8 0.4 1.1e-55 188.8 0.4 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCC70646.1 - 6.7e-21 74.7 0.5 1.5e-17 63.9 0.1 3.6 3 2 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCC70646.1 - 8.8e-11 42.1 2.7 1.4e-10 41.4 0.0 2.8 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCC70646.1 - 2e-06 27.7 0.0 4.6e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CCC70646.1 - 6.8e-06 25.5 0.2 6.8e-06 25.5 0.2 1.9 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase CUE PF02845.16 CCC70646.1 - 7.4e-05 22.4 0.1 0.00019 21.1 0.1 1.7 1 0 0 1 1 1 1 CUE domain Allexi_40kDa PF05549.11 CCC70646.1 - 0.026 14.1 1.0 0.89 9.0 0.1 2.5 2 0 0 2 2 2 0 Allexivirus 40kDa protein PBP1_TM PF14812.6 CCC70646.1 - 5.7 7.4 23.7 0.051 14.0 6.4 3.5 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RCC1 PF00415.18 CCC70647.1 - 1e-20 74.1 5.5 3.4e-08 34.0 0.0 6.6 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCC70647.1 - 1.1e-17 63.3 13.7 1.2e-07 31.4 0.1 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat DUF1262 PF06880.11 CCC70647.1 - 0.11 13.0 0.1 0.29 11.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1262) Exo_endo_phos PF03372.23 CCC70648.1 - 1.3e-21 77.2 0.0 4.6e-21 75.4 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.7 CCC70648.1 - 4.6e-09 36.4 14.8 3.6e-05 24.1 0.7 4.1 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 CCC70648.1 - 6.9e-08 32.1 10.8 8e-07 28.7 6.2 3.1 2 1 1 3 3 3 2 Leucine rich repeat Eaf7 PF07904.13 CCC70648.1 - 0.31 11.4 4.0 0.4 11.1 0.2 3.0 3 0 0 3 3 3 0 Chromatin modification-related protein EAF7 Euplotes_phero PF05842.11 CCC70648.1 - 1.2 9.7 6.5 1.5 9.4 4.9 1.9 1 1 0 1 1 1 0 Euplotes octocarinatus mating pheromone protein Nucleoside_tran PF01733.18 CCC70649.1 - 6.7e-70 235.9 12.0 6.7e-70 235.9 12.0 1.5 2 0 0 2 2 2 1 Nucleoside transporter PMT PF02366.18 CCC70650.1 - 9.1e-96 320.2 19.4 9.1e-96 320.2 19.4 2.2 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCC70650.1 - 7e-59 198.8 15.9 7e-59 198.8 15.9 2.7 2 1 1 3 3 3 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCC70650.1 - 1.3e-19 70.8 0.3 2.9e-19 69.6 0.3 1.5 1 0 0 1 1 1 1 MIR domain RasGEF PF00617.19 CCC70651.1 - 3.5e-42 144.6 4.0 3.1e-41 141.5 2.0 2.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 CCC70651.1 - 1.2e-11 44.7 1.6 1.2e-11 44.7 1.6 3.0 3 0 0 3 3 3 1 RasGEF N-terminal motif NB-ARC PF00931.22 CCC70654.1 - 0.023 13.9 0.1 0.035 13.3 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain T4_tail_cap PF11091.8 CCC70654.1 - 0.034 13.1 0.0 0.037 12.9 0.0 1.1 1 0 0 1 1 1 0 Tail-tube assembly protein PhoLip_ATPase_C PF16212.5 CCC70655.1 - 2.5e-83 279.7 27.5 2.5e-83 279.7 27.5 3.4 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 CCC70655.1 - 1.3e-24 85.7 5.0 1.3e-24 85.7 5.0 2.1 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 CCC70655.1 - 8.9e-11 42.5 0.2 9.5e-05 22.8 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 CCC70655.1 - 1.3e-10 41.2 0.0 1.7e-09 37.6 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 CCC70655.1 - 2.1e-06 27.4 0.0 4.7e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 CCC70655.1 - 0.00089 19.1 0.1 0.018 14.8 0.0 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Saw1 PF11561.8 CCC70656.1 - 2.4e-88 295.8 3.8 2.7e-88 295.6 3.8 1.0 1 0 0 1 1 1 1 Single strand annealing-weakened 1 bPH_5 PF10882.8 CCC70656.1 - 0.083 13.0 0.1 0.2 11.7 0.1 1.7 1 1 0 1 1 1 0 Bacterial PH domain Hph PF13694.6 CCC70657.1 - 2.3e-12 47.6 13.2 2.3e-12 47.6 13.2 3.9 2 1 1 3 3 3 1 Sec63/Sec62 complex-interacting family Myosin_head PF00063.21 CCC70658.1 - 3.7e-274 911.1 18.2 3.7e-274 911.1 18.2 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 CCC70658.1 - 1.1e-19 70.6 5.2 1.1e-19 70.6 5.2 2.7 2 0 0 2 2 2 1 DIL domain AAA_22 PF13401.6 CCC70658.1 - 0.0011 19.3 0.2 0.027 14.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.27 CCC70658.1 - 0.0033 17.9 0.2 0.049 14.1 0.1 3.0 2 0 0 2 2 2 1 ABC transporter T2SSE PF00437.20 CCC70658.1 - 0.015 14.4 1.7 0.062 12.3 0.0 2.5 2 1 1 3 3 3 0 Type II/IV secretion system protein RNA_helicase PF00910.22 CCC70658.1 - 0.015 15.7 0.1 4.7 7.6 0.0 3.1 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 CCC70658.1 - 0.031 14.7 0.2 0.16 12.3 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain HSF_DNA-bind PF00447.17 CCC70658.1 - 0.034 14.7 1.7 0.12 13.0 0.8 2.5 2 0 0 2 2 2 0 HSF-type DNA-binding DUF2935 PF11155.8 CCC70658.1 - 0.051 13.9 0.7 0.4 11.0 0.7 2.7 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) IQ PF00612.27 CCC70658.1 - 0.13 12.1 15.3 18 5.4 0.1 6.1 7 0 0 7 7 7 0 IQ calmodulin-binding motif EAP30 PF04157.16 CCC70658.1 - 0.47 9.7 6.3 5 6.3 2.2 3.1 2 1 1 3 3 3 0 EAP30/Vps36 family vATP-synt_E PF01991.18 CCC70659.1 - 5.2e-60 202.3 19.6 6.2e-60 202.0 19.6 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phlebovirus_NSM PF07246.11 CCC70659.1 - 0.003 17.0 7.7 0.0048 16.3 7.7 1.3 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M Polysacc_deac_1 PF01522.21 CCC70659.1 - 0.0088 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase LMBR1 PF04791.16 CCC70659.1 - 2.1 7.1 4.3 2.5 6.9 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF4162 PF13732.6 CCC70659.1 - 5 7.9 9.9 0.84 10.4 3.6 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4162) EMP24_GP25L PF01105.24 CCC70661.1 - 3.3e-36 124.9 0.3 3.9e-36 124.7 0.3 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF5038 PF16441.5 CCC70661.1 - 0.021 14.9 0.0 0.029 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5038) Mgr1 PF08602.10 CCC70661.1 - 0.022 13.6 0.0 0.025 13.4 0.0 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit DUF4869 PF16163.5 CCC70661.1 - 0.077 12.7 0.1 0.21 11.3 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4869) Kisspeptin PF15152.6 CCC70661.1 - 0.17 12.7 0.0 0.64 10.8 0.0 1.9 1 1 1 2 2 2 0 Kisspeptin DUF997 PF06196.12 CCC70661.1 - 0.32 11.0 3.8 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF997) FUN14 PF04930.15 CCC70662.1 - 0.0027 18.1 1.5 0.0027 18.1 1.5 1.8 2 0 0 2 2 2 1 FUN14 family Spo7 PF03907.13 CCC70663.1 - 7.7e-72 241.3 4.7 1.2e-71 240.8 4.7 1.3 1 0 0 1 1 1 1 Spo7-like protein MDM10 PF12519.8 CCC70664.1 - 7.6e-140 466.8 24.4 8.7e-140 466.7 24.4 1.0 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 BLM10_N PF16547.5 CCC70665.1 - 0.33 11.3 12.6 21 5.5 0.1 3.8 3 0 0 3 3 3 0 Proteasome-substrate-size regulator, N-terminal GCR1_C PF12550.8 CCC70666.1 - 2.2e-23 82.4 0.5 5e-23 81.2 0.5 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Utp11 PF03998.13 CCC70666.1 - 0.0012 18.8 3.8 0.0025 17.8 3.8 1.6 1 0 0 1 1 1 1 Utp11 protein FliJ PF02050.16 CCC70666.1 - 0.0045 17.2 1.9 0.014 15.6 1.9 1.8 1 0 0 1 1 1 1 Flagellar FliJ protein DUF4061 PF13270.6 CCC70666.1 - 0.033 14.5 2.4 0.12 12.7 2.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) DsrC PF04358.13 CCC70666.1 - 0.035 14.6 0.1 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 DsrC like protein DUF977 PF06163.11 CCC70666.1 - 0.1 12.5 0.0 0.27 11.2 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF977) STAT_alpha PF01017.20 CCC70666.1 - 0.14 12.0 7.1 0.11 12.3 5.6 1.7 2 0 0 2 2 2 0 STAT protein, all-alpha domain SR-25 PF10500.9 CCC70666.1 - 0.19 11.3 21.5 0.068 12.8 4.8 3.1 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein CENP-H PF05837.12 CCC70666.1 - 1.3 9.4 4.9 0.55 10.7 1.5 2.1 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SRAP PF02586.14 CCC70667.1 - 8.3e-67 224.9 0.4 1e-66 224.6 0.4 1.1 1 0 0 1 1 1 1 SOS response associated peptidase (SRAP) TPR_10 PF13374.6 CCC70668.1 - 0.0027 17.5 3.8 5.9 6.9 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCC70668.1 - 0.0031 17.8 4.0 5.3 7.4 0.1 4.4 5 1 0 5 5 5 2 Tetratricopeptide repeat Swi5 PF07061.11 CCC70668.1 - 0.0069 16.4 0.6 0.022 14.8 0.6 1.8 1 0 0 1 1 1 1 Swi5 Adeno_Penton_B PF01686.17 CCC70668.1 - 0.046 12.2 0.0 0.065 11.7 0.0 1.3 1 0 0 1 1 1 0 Adenovirus penton base protein TPR_14 PF13428.6 CCC70668.1 - 0.2 12.6 0.2 52 5.1 0.0 3.2 3 1 1 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 CCC70669.1 - 6.2e-45 150.3 11.5 2.4e-07 31.3 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC70669.1 - 5.3e-10 39.5 1.3 0.01 16.1 0.0 4.6 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCC70669.1 - 8.2e-07 28.3 0.6 0.046 12.7 0.0 4.0 2 1 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 CCC70669.1 - 1.3e-06 27.3 3.1 0.01 14.5 0.1 4.3 2 1 3 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.11 CCC70669.1 - 4.3e-05 23.5 0.2 0.0048 16.8 0.1 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 CCC70669.1 - 0.015 14.0 0.5 1.1 7.9 0.5 2.6 1 1 1 2 2 2 0 Nup133 N terminal like PD40 PF07676.12 CCC70669.1 - 0.048 13.6 0.0 19 5.4 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Spc24 PF08286.11 CCC70670.1 - 9.4e-22 77.2 11.6 1.7e-21 76.4 1.3 2.7 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 LemA PF04011.12 CCC70670.1 - 5.3e-05 23.1 0.4 8.4e-05 22.5 0.4 1.3 1 0 0 1 1 1 1 LemA family GLE1 PF07817.13 CCC70670.1 - 0.0067 15.7 0.8 0.0096 15.2 0.8 1.4 1 0 0 1 1 1 1 GLE1-like protein APG6_N PF17675.1 CCC70670.1 - 0.0098 16.4 3.3 0.016 15.8 3.3 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region GrpE PF01025.19 CCC70670.1 - 0.013 15.2 1.8 0.019 14.6 1.8 1.3 1 0 0 1 1 1 0 GrpE End_N_terminal PF12218.8 CCC70670.1 - 0.09 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Allexi_40kDa PF05549.11 CCC70670.1 - 0.098 12.2 2.9 0.13 11.7 2.9 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein TMPIT PF07851.13 CCC70670.1 - 0.14 11.4 1.9 0.19 10.9 1.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein zf-C3HC4_3 PF13920.6 CCC70671.1 - 2.7e-09 36.7 12.6 5.2e-09 35.8 12.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 CCC70671.1 - 2.1 8.3 12.4 4.3 7.3 12.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 AICARFT_IMPCHas PF01808.18 CCC70672.1 - 2.2e-92 309.7 0.0 3.2e-92 309.1 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 CCC70672.1 - 1.5e-23 82.8 0.3 3.6e-23 81.6 0.0 1.8 2 0 0 2 2 2 1 MGS-like domain TMEM223 PF14640.6 CCC70673.1 - 0.1 12.8 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein 223 Pkr1 PF08636.10 CCC70674.1 - 2.7e-30 104.3 11.4 3.5e-30 104.0 11.4 1.1 1 0 0 1 1 1 1 ER protein Pkr1 VEGFR-2_TMD PF17988.1 CCC70674.1 - 6.1 6.4 7.9 13 5.3 0.7 2.5 2 0 0 2 2 2 0 VEGFR-2 Transmembrane domain MIF4G_like PF09088.11 CCC70676.1 - 1.2e-54 185.0 1.2 2.8e-54 183.8 1.2 1.6 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.11 CCC70676.1 - 5.3e-54 183.5 6.1 9.5e-53 179.4 1.0 3.4 3 1 0 3 3 3 1 MIF4G like MIF4G PF02854.19 CCC70676.1 - 6.6e-13 48.8 3.3 6.6e-13 48.8 3.3 2.5 2 1 1 3 3 3 1 MIF4G domain DnaB_2 PF07261.11 CCC70676.1 - 0.0071 16.1 0.7 6.2 6.6 0.0 4.2 2 1 1 3 3 3 2 Replication initiation and membrane attachment Cnd1 PF12717.7 CCC70676.1 - 0.11 12.5 3.3 0.16 12.0 0.2 2.8 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF3810 PF12725.7 CCC70677.1 - 0.33 10.2 1.5 16 4.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3810) Phage_holin_3_6 PF07332.11 CCC70677.1 - 1.3 9.1 3.1 2 8.5 3.1 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III MOZ_SAS PF01853.18 CCC70678.1 - 2.1e-57 193.7 0.5 3.1e-57 193.1 0.5 1.2 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 CCC70678.1 - 8e-08 31.8 3.8 4.8e-06 26.1 2.0 2.6 2 0 0 2 2 2 2 MYST family zinc finger domain Acetyltransf_7 PF13508.7 CCC70678.1 - 0.042 14.3 0.0 0.087 13.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UL141 PF16758.5 CCC70679.1 - 0.013 15.3 0.0 0.052 13.3 0.0 2.0 2 0 0 2 2 2 0 Herpes-like virus membrane glycoprotein UL141 HAD_2 PF13419.6 CCC70680.1 - 1.7e-08 34.7 0.1 4.2e-08 33.5 0.1 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCC70680.1 - 1.5e-07 31.3 0.0 3e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CCC70680.1 - 2.2e-07 31.4 0.0 4.7e-07 30.3 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase CAF1C_H4-bd PF12265.8 CCC70681.1 - 1.6e-15 57.1 0.0 5.3e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 CCC70681.1 - 8.9e-11 42.2 8.7 0.0026 18.6 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC70681.1 - 2e-07 31.2 1.6 0.016 15.5 0.3 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain NFACT-R_1 PF05670.13 CCC70682.1 - 4.3e-33 114.2 0.0 7.5e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain Abhydrolase_1 PF00561.20 CCC70683.1 - 1.2 8.8 3.4 1 8.9 1.6 1.9 2 1 0 2 2 2 0 alpha/beta hydrolase fold CLTH PF10607.9 CCC70685.1 - 1e-22 80.6 6.5 1e-22 80.6 6.5 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Vta1 PF04652.16 CCC70685.1 - 1.5 8.8 6.9 0.29 11.1 1.8 2.1 2 0 0 2 2 2 0 Vta1 like RhoGAP PF00620.27 CCC70686.1 - 0.00049 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain APG6_N PF17675.1 CCC70686.1 - 0.34 11.5 5.8 11 6.5 0.4 3.6 4 0 0 4 4 4 0 Apg6 coiled-coil region 6PGD PF00393.19 CCC70687.1 - 3.7e-125 417.1 0.0 4.6e-125 416.8 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 CCC70687.1 - 1.1e-50 171.9 0.0 1.6e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.17 CCC70687.1 - 0.022 15.3 0.0 0.043 14.4 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.6 CCC70687.1 - 0.074 13.3 0.0 0.26 11.6 0.0 1.9 2 0 0 2 2 2 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.19 CCC70687.1 - 0.13 11.7 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Raptor_N PF14538.6 CCC70689.1 - 3.1e-67 225.1 0.0 3.1e-67 225.1 0.0 3.0 3 0 0 3 3 3 1 Raptor N-terminal CASPase like domain HEAT PF02985.22 CCC70689.1 - 9.5e-06 25.5 0.1 0.09 13.1 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 CCC70689.1 - 0.00071 19.7 4.4 0.099 12.7 1.8 2.7 1 1 1 2 2 2 2 non-SMC mitotic condensation complex subunit 1 BBS2_Mid PF14783.6 CCC70689.1 - 0.00082 19.4 2.7 0.21 11.6 0.1 3.1 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 CCC70689.1 - 0.05 14.5 7.2 19 6.3 0.0 5.9 5 1 1 6 6 6 0 WD domain, G-beta repeat HEAT_2 PF13646.6 CCC70689.1 - 0.18 12.2 0.0 2.6 8.5 0.0 2.8 2 0 0 2 2 2 0 HEAT repeats Cpn60_TCP1 PF00118.24 CCC70690.1 - 2.4e-149 498.1 6.9 2.8e-149 497.9 6.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.17 CCC70690.1 - 0.058 13.7 0.1 0.45 10.9 0.0 2.4 2 0 0 2 2 2 0 Dinitrogenase iron-molybdenum cofactor Vps53_N PF04100.12 CCC70691.1 - 9.4e-88 294.7 17.6 1.9e-87 293.7 17.6 1.5 1 0 0 1 1 1 1 Vps53-like, N-terminal VPS53_C PF16854.5 CCC70691.1 - 1e-85 286.7 5.6 1e-85 286.7 5.6 2.6 3 0 0 3 3 3 1 Vacuolar protein sorting-associated protein 53 C-terminus TcdB_N PF12918.7 CCC70691.1 - 0.017 15.4 0.3 0.017 15.4 0.3 3.3 4 0 0 4 4 4 0 TcdB toxin N-terminal helical domain BORCS7 PF16088.5 CCC70691.1 - 0.15 12.3 3.8 0.14 12.4 1.4 2.4 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 7 YkyA PF10368.9 CCC70691.1 - 0.27 10.9 6.1 0.11 12.2 1.1 2.7 3 0 0 3 3 3 0 Putative cell-wall binding lipoprotein DivIVA PF05103.13 CCC70691.1 - 0.33 11.0 8.1 0.082 13.0 0.5 3.5 3 1 1 4 4 4 0 DivIVA protein Sec34 PF04136.15 CCC70691.1 - 0.56 10.1 9.7 0.25 11.2 1.6 3.3 3 0 0 3 3 3 0 Sec34-like family 7TMR-HDED PF07697.11 CCC70691.1 - 0.76 9.9 7.3 1.9 8.6 1.6 3.4 2 1 0 2 2 2 0 7TM-HD extracellular PPTA PF01239.22 CCC70692.1 - 6.8e-38 127.3 20.2 6.7e-09 35.2 1.1 6.1 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat IES5 PF17335.2 CCC70692.1 - 0.0009 19.5 5.6 0.96 9.7 0.0 3.3 3 0 0 3 3 3 2 Ino80 complex subunit 5 Baculo_LEF-11 PF06385.12 CCC70692.1 - 0.0065 16.9 0.8 0.0065 16.9 0.8 2.4 2 1 2 4 4 4 1 Baculovirus LEF-11 protein Cyclin_N PF00134.23 CCC70693.1 - 3.8e-09 36.4 3.8 3.8e-09 36.4 3.8 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.19 CCC70693.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat DUF3591 PF12157.8 CCC70694.1 - 1.3e-171 571.1 1.5 2.1e-171 570.4 1.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.6 CCC70694.1 - 1.9e-05 24.4 0.3 4.1e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF3135 PF11333.8 CCC70694.1 - 0.091 13.0 1.0 0.16 12.3 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) zf-CCHC PF00098.23 CCC70694.1 - 0.14 12.3 1.7 0.15 12.2 0.4 1.7 2 0 0 2 2 2 0 Zinc knuckle DUF1840 PF08895.11 CCC70694.1 - 0.51 10.7 3.8 1.1 9.6 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1840) Peptidase_S10 PF00450.22 CCC70696.1 - 1.2e-126 423.6 0.2 1.4e-126 423.3 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.11 CCC70696.1 - 1.2e-12 48.4 3.9 7.7e-12 45.9 3.1 2.6 1 1 1 2 2 2 1 Carboxypeptidase Y pro-peptide Aminotran_1_2 PF00155.21 CCC70697.1 - 1.2e-62 212.2 0.0 1.5e-62 211.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2406 PF10295.9 CCC70698.1 - 9.6e-29 99.9 1.7 9.9e-29 99.8 0.5 1.6 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) Dynamitin PF04912.14 CCC70699.1 - 5.4e-15 55.6 28.5 5.2e-12 45.8 28.5 2.1 1 1 0 1 1 1 1 Dynamitin Alpha-E PF04168.12 CCC70699.1 - 0.069 12.9 3.2 0.18 11.6 0.2 3.0 3 1 0 3 3 3 0 A predicted alpha-helical domain with a conserved ER motif. Reovirus_cap PF00979.17 CCC70699.1 - 0.12 11.5 0.1 0.22 10.7 0.1 1.3 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 DUF948 PF06103.11 CCC70699.1 - 0.16 12.3 0.3 0.16 12.3 0.3 3.2 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Holin_BhlA PF10960.8 CCC70699.1 - 0.5 10.4 0.1 0.5 10.4 0.1 3.6 3 2 2 5 5 5 0 BhlA holin family Sulfatase_C PF14707.6 CCC70699.1 - 0.89 10.3 4.0 0.92 10.3 0.5 2.7 2 1 0 3 3 3 0 C-terminal region of aryl-sulfatase V-ATPase_G PF03179.15 CCC70699.1 - 1.3 9.6 14.9 0.88 10.1 0.4 3.8 3 1 1 4 4 4 0 Vacuolar (H+)-ATPase G subunit Noelin-1 PF12308.8 CCC70699.1 - 1.7 8.7 11.2 0.72 9.9 0.8 4.0 2 1 3 5 5 5 0 Neurogenesis glycoprotein DUF2443 PF10398.9 CCC70699.1 - 1.8 8.7 7.4 0.19 11.8 1.0 2.9 3 1 1 4 4 3 0 Protein of unknown function (DUF2443) CLZ PF16526.5 CCC70699.1 - 1.8 8.9 19.9 0.83 10.0 0.1 5.7 4 3 1 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PspB PF06667.12 CCC70699.1 - 1.9 8.6 4.6 11 6.1 0.3 3.1 2 1 0 2 2 2 0 Phage shock protein B DUF1664 PF07889.12 CCC70699.1 - 3.4 7.7 18.5 0.17 12.0 3.3 4.2 1 1 5 6 6 6 0 Protein of unknown function (DUF1664) DUF745 PF05335.13 CCC70699.1 - 3.4 7.4 7.1 0.28 10.9 0.6 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF745) FeoB_Cyto PF17910.1 CCC70699.1 - 3.4 8.3 14.8 12 6.6 9.1 3.5 2 2 0 2 2 2 0 FeoB cytosolic helical domain DASH_Dad4 PF08650.10 CCC70699.1 - 4 7.5 9.2 1.8 8.6 1.5 3.4 4 0 0 4 4 4 0 DASH complex subunit Dad4 Occludin_ELL PF07303.13 CCC70699.1 - 9.9 7.0 17.9 12 6.7 5.6 4.0 3 1 0 3 3 3 0 Occludin homology domain Amidase PF01425.21 CCC70700.1 - 1.7e-112 376.7 0.0 1.9e-112 376.6 0.0 1.0 1 0 0 1 1 1 1 Amidase Got1 PF04178.12 CCC70701.1 - 2.2e-14 53.8 8.9 2.6e-14 53.6 8.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family PEMT PF04191.13 CCC70701.1 - 1.2 9.6 6.9 0.39 11.1 2.4 2.1 1 1 0 2 2 2 0 Phospholipid methyltransferase Prp19 PF08606.11 CCC70702.1 - 1.5e-29 101.8 1.3 2.3e-29 101.2 1.3 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like zf-Nse PF11789.8 CCC70702.1 - 0.00052 19.8 0.0 0.0014 18.4 0.0 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 CCC70702.1 - 0.0019 18.4 0.0 0.0051 17.0 0.0 1.8 1 0 0 1 1 1 1 U-box domain Pkinase PF00069.25 CCC70703.1 - 7.8e-47 159.9 1.4 1.3e-38 132.8 0.0 2.7 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70703.1 - 3.3e-20 72.5 0.2 1.5e-17 63.8 0.0 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC70703.1 - 1.6e-06 27.2 0.0 1.6e-06 27.2 0.0 2.2 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CCC70703.1 - 0.00015 21.2 0.9 0.059 12.7 0.0 2.7 3 0 0 3 3 3 2 Kinase-like DEAD PF00270.29 CCC70704.1 - 2.6e-46 157.6 0.6 6.7e-46 156.3 0.0 2.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC70704.1 - 2.1e-25 89.2 0.2 2.1e-24 86.0 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCC70704.1 - 5.9e-19 68.0 0.4 1.1e-18 67.2 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCC70704.1 - 1.6e-05 25.0 0.0 3.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCC70704.1 - 0.00012 21.4 0.0 0.00034 19.9 0.0 1.7 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase SecA_DEAD PF07517.14 CCC70704.1 - 0.012 14.9 0.0 0.042 13.2 0.0 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain AAA_22 PF13401.6 CCC70704.1 - 0.069 13.4 0.5 0.36 11.1 0.1 2.4 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 CCC70704.1 - 0.15 11.8 0.0 1.1 8.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain tRNA-synt_1g PF09334.11 CCC70705.1 - 3.1e-156 520.1 0.1 4.2e-156 519.6 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.10 CCC70705.1 - 2.2e-29 102.4 5.0 7.2e-29 100.8 5.0 1.9 1 0 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1 PF00133.22 CCC70705.1 - 5.4e-10 38.2 0.3 0.00047 18.5 0.0 2.6 1 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 CCC70705.1 - 0.0083 15.5 0.1 0.052 12.9 0.0 2.2 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Sigma54_CBD PF04963.13 CCC70705.1 - 0.04 13.8 0.2 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 factor, core binding domain DUF2738 PF10927.8 CCC70705.1 - 0.052 12.6 0.0 0.097 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2738) Anticodon_1 PF08264.13 CCC70705.1 - 0.089 12.8 0.4 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA Aminotran_4 PF01063.19 CCC70706.1 - 3.4e-22 79.4 0.0 5.1e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Amino-transferase class IV HEAT_2 PF13646.6 CCC70707.1 - 3.9e-14 52.8 0.3 0.11 12.9 0.0 8.8 6 2 4 10 10 10 3 HEAT repeats HEAT PF02985.22 CCC70707.1 - 2.6e-13 49.0 3.7 2.2 8.7 0.1 10.1 10 0 0 10 10 10 4 HEAT repeat HEAT_EZ PF13513.6 CCC70707.1 - 2.5e-11 43.8 0.1 0.05 14.1 0.0 7.4 8 1 0 8 8 8 2 HEAT-like repeat Cnd1 PF12717.7 CCC70707.1 - 3.2e-06 27.3 6.0 3.2 7.8 0.5 6.6 6 3 1 7 7 7 2 non-SMC mitotic condensation complex subunit 1 MMS19_C PF12460.8 CCC70707.1 - 5.9e-06 25.7 2.4 0.32 10.0 0.0 5.1 4 1 1 5 5 5 3 RNAPII transcription regulator C-terminal Adaptin_N PF01602.20 CCC70707.1 - 8.3e-06 24.6 7.0 0.00061 18.5 1.8 3.6 2 1 0 2 2 2 1 Adaptin N terminal region DUF3385 PF11865.8 CCC70707.1 - 1.4e-05 25.0 7.4 0.19 11.6 0.1 5.2 4 2 0 5 5 5 2 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 CCC70707.1 - 1.8e-05 25.2 2.4 0.088 13.4 0.0 5.8 7 1 0 7 7 7 1 Vacuolar 14 Fab1-binding region Dopey_N PF04118.14 CCC70707.1 - 0.0061 15.7 0.2 6.3 5.8 0.1 3.5 3 0 0 3 3 3 1 Dopey, N-terminal NUC173 PF08161.12 CCC70707.1 - 0.061 13.0 0.2 1.6 8.3 0.0 3.6 2 1 1 4 4 4 0 NUC173 domain Gpi16 PF04113.14 CCC70708.1 - 1.2e-184 614.9 0.0 1.6e-184 614.5 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component HMw1_D2 PF18254.1 CCC70708.1 - 0.15 12.5 0.1 2.8 8.3 0.1 2.9 2 0 0 2 2 2 0 HMW1 domain 2 Elong_Iki1 PF10483.9 CCC70709.1 - 8.4e-77 258.6 7.4 9.6e-77 258.4 7.4 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 ELP6 PF09807.9 CCC70709.1 - 0.032 13.6 0.7 0.57 9.6 0.1 2.2 2 0 0 2 2 2 0 Elongation complex protein 6 NACHT PF05729.12 CCC70709.1 - 0.089 12.7 0.1 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 NACHT domain TQ PF18202.1 CCC70709.1 - 0.12 12.9 2.2 0.4 11.2 1.0 2.1 2 0 0 2 2 2 0 T-Q ester bond containing domain PIEZO PF15917.5 CCC70709.1 - 0.18 11.3 1.6 0.27 10.7 1.6 1.2 1 0 0 1 1 1 0 Piezo PUF PF00806.19 CCC70710.1 - 1.2e-34 116.1 9.3 5.9e-06 25.7 0.0 9.5 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat DUF5377 PF17347.2 CCC70710.1 - 0.08 13.3 0.3 3.1 8.2 0.2 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5377) FAM176 PF14851.6 CCC70710.1 - 3.9 7.1 6.3 3.5 7.3 3.9 2.2 2 0 0 2 2 2 0 FAM176 family DUF3294 PF07957.11 CCC70711.1 - 5.1e-87 291.1 2.9 5.7e-87 290.9 2.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DUF2959 PF11172.8 CCC70711.1 - 0.014 15.6 1.4 0.024 14.8 0.4 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) Tricorn_C1 PF14684.6 CCC70711.1 - 0.12 12.5 0.2 16 5.7 0.0 3.1 3 0 0 3 3 3 0 Tricorn protease C1 domain Rotavirus_VP7 PF05868.11 CCC70711.1 - 0.12 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 Swm2 PF17083.5 CCC70711.1 - 0.21 11.6 3.3 7 6.7 1.1 2.2 2 0 0 2 2 2 0 Nucleolar protein Swm2 BRE1 PF08647.11 CCC70711.1 - 2.8 8.1 7.5 2.7 8.1 1.1 3.0 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase LTV PF04180.14 CCC70712.1 - 5.2e-112 375.4 31.9 6.5e-112 375.0 31.9 1.1 1 0 0 1 1 1 1 Low temperature viability protein RNA_pol_Rbc25 PF08292.12 CCC70713.1 - 4.6e-49 166.0 4.1 1.1e-48 164.7 4.1 1.6 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 CCC70713.1 - 7e-21 74.4 0.0 1e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 CCC70713.1 - 0.0027 18.0 0.2 0.01 16.2 0.0 2.1 2 1 0 2 2 2 1 S1 RNA binding domain RPA43_OB PF17875.1 CCC70713.1 - 0.24 12.0 3.2 0.56 10.8 3.2 1.7 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I AAA PF00004.29 CCC70714.1 - 1.7e-40 138.5 0.0 3.3e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC70714.1 - 2.2e-06 27.4 0.0 5.7e-06 26.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 CCC70714.1 - 6.1e-05 23.0 0.0 0.0002 21.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCC70714.1 - 8.3e-05 22.9 0.0 0.0029 17.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 CCC70714.1 - 0.00016 21.8 0.0 0.00037 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCC70714.1 - 0.00024 21.5 0.1 0.0042 17.5 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 CCC70714.1 - 0.001 18.3 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 CCC70714.1 - 0.0029 17.3 0.0 0.0055 16.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 CCC70714.1 - 0.014 15.7 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CCC70714.1 - 0.024 14.4 0.0 0.08 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CCC70714.1 - 0.026 14.7 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCC70714.1 - 0.029 14.9 0.0 0.082 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CCC70714.1 - 0.029 14.7 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 CCC70714.1 - 0.037 13.5 0.0 0.087 12.3 0.0 1.6 1 1 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 CCC70714.1 - 0.05 13.0 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CCC70714.1 - 0.05 13.5 0.0 0.092 12.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 CCC70714.1 - 0.054 13.4 1.8 6 6.7 0.0 3.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea TIP49 PF06068.13 CCC70714.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_14 PF13173.6 CCC70714.1 - 0.11 12.5 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 CCC70714.1 - 0.12 12.1 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CCC70714.1 - 0.24 11.2 1.9 0.97 9.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Aa_trans PF01490.18 CCC70715.1 - 8.9e-97 324.4 34.5 1.1e-96 324.1 34.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.6 CCC70715.1 - 0.67 8.7 37.9 0.094 11.5 24.0 2.1 1 1 1 2 2 2 0 Amino acid permease FAD_binding_2 PF00890.24 CCC70716.1 - 1.2e-121 406.7 3.1 1.5e-121 406.4 3.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 CCC70716.1 - 3.2e-45 153.2 0.4 4.9e-45 152.7 0.4 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 CCC70716.1 - 0.00018 20.8 0.1 0.017 14.3 0.0 2.4 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 CCC70716.1 - 0.00071 18.9 0.2 0.0017 17.6 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCC70716.1 - 0.00073 18.7 1.9 0.034 13.2 1.8 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CCC70716.1 - 0.01 15.1 1.1 0.034 13.4 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.24 CCC70716.1 - 0.12 12.0 1.9 0.48 10.0 1.9 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase DBR1 PF05011.13 CCC70717.1 - 4.8e-11 43.2 2.0 5.7e-11 43.0 0.0 2.1 3 0 0 3 3 3 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 CCC70717.1 - 7.2e-08 33.2 0.1 1.9e-07 31.8 0.1 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase FAD_binding_6 PF00970.24 CCC70718.1 - 1.6e-26 92.5 0.0 2.8e-26 91.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 CCC70718.1 - 7.3e-26 90.9 0.0 1.1e-25 90.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 CCC70718.1 - 0.00034 20.8 0.0 0.0069 16.5 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF4465 PF14717.6 CCC70718.1 - 0.031 14.6 0.0 0.085 13.2 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4465) Carb_kinase PF01256.17 CCC70719.1 - 2.9e-69 233.2 0.0 2.7e-68 230.1 0.0 1.9 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 CCC70719.1 - 2.1e-05 24.0 0.0 2.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.15 CCC70719.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family GLEYA PF10528.9 CCC70720.1 - 2.9e-33 114.1 24.6 6.6e-18 64.9 3.8 4.1 4 0 0 4 4 4 2 GLEYA domain PA14 PF07691.12 CCC70720.1 - 5.3e-20 71.7 3.8 3.2e-09 36.7 0.1 3.1 3 0 0 3 3 3 2 PA14 domain His_Phos_1 PF00300.22 CCC70721.1 - 6.5e-38 130.4 0.0 9.5e-30 103.7 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) Tnp_22_dsRBD PF17490.2 CCC70721.1 - 0.036 14.1 0.0 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 L1 transposable element dsRBD-like domain SRPRB PF09439.10 CCC70722.1 - 1e-57 194.5 1.5 1.3e-57 194.1 1.5 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 CCC70722.1 - 1.2e-12 47.6 0.1 1.6e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCC70722.1 - 1.4e-09 38.0 0.1 3.1e-09 36.9 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCC70722.1 - 7.6e-06 25.5 0.1 1.4e-05 24.7 0.1 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 CCC70722.1 - 0.00011 22.0 0.7 0.00019 21.3 0.6 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 CCC70722.1 - 0.00014 21.8 0.2 0.018 15.0 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CCC70722.1 - 0.0025 17.4 0.1 0.018 14.6 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 CCC70722.1 - 0.014 15.2 0.0 0.048 13.4 0.0 1.8 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF4848 PF16140.5 CCC70722.1 - 0.019 14.6 0.0 0.029 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4848) Roc PF08477.13 CCC70722.1 - 0.034 14.4 0.0 0.077 13.2 0.0 1.7 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 CCC70722.1 - 0.092 12.4 0.1 0.22 11.1 0.0 1.7 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 CCC70722.1 - 0.34 11.4 4.7 0.48 10.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain Rsm22 PF09243.10 CCC70723.1 - 3.6e-30 105.2 1.6 1.7e-10 40.6 0.0 4.4 4 1 0 4 4 4 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_11 PF08241.12 CCC70723.1 - 0.0057 17.3 0.0 4.5 8.0 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 CCC70723.1 - 0.018 14.9 0.0 0.054 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain RNA_pol_Rpb4 PF03874.16 CCC70723.1 - 0.083 13.2 2.2 0.25 11.7 0.0 2.6 3 0 0 3 3 3 0 RNA polymerase Rpb4 Methyltransf_12 PF08242.12 CCC70723.1 - 0.09 13.5 3.4 0.12 13.1 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Ribosomal_S27e PF01667.17 CCC70724.1 - 1.6e-29 101.4 3.5 2.1e-29 101.0 3.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.21 CCC70724.1 - 0.0099 16.1 0.8 0.011 15.9 0.8 1.2 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 CCC70724.1 - 0.024 14.2 4.2 0.035 13.6 4.2 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zf-ACC PF17848.1 CCC70724.1 - 3.2 7.9 6.4 19 5.4 0.2 2.3 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain Pkinase PF00069.25 CCC70725.1 - 1.8e-54 184.9 0.1 2.3e-54 184.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70725.1 - 3.7e-26 92.0 0.0 6.1e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FOXO-TAD PF16676.5 CCC70725.1 - 0.017 15.5 1.4 0.45 11.0 0.2 2.6 2 0 0 2 2 2 0 Transactivation domain of FOXO protein family ARS2 PF04959.13 CCC70725.1 - 0.15 12.4 0.1 0.41 11.0 0.1 1.7 2 0 0 2 2 2 0 Arsenite-resistance protein 2 Calcipressin PF04847.12 CCC70726.1 - 1.9e-26 93.0 0.1 2.5e-26 92.6 0.1 1.2 1 0 0 1 1 1 1 Calcipressin Peptidase_M1 PF01433.20 CCC70727.1 - 5.8e-87 290.8 5.9 2.3e-86 288.9 5.6 2.0 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 CCC70727.1 - 1.2e-81 274.7 1.0 4e-80 269.7 0.1 2.5 2 1 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 CCC70727.1 - 1.9e-52 178.2 4.9 2.9e-52 177.6 1.3 2.2 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain RNase_H2-Ydr279 PF09468.10 CCC70728.1 - 5.9e-22 78.6 1.0 5.9e-22 78.6 1.0 1.9 2 1 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 CCC70728.1 - 1.3e-13 51.0 0.5 2.3e-13 50.2 0.5 1.4 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain HetR_C PF18460.1 CCC70728.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 Heterocyst differentiation regulator C-terminal Hood domain adh_short PF00106.25 CCC70729.1 - 8e-08 32.0 0.0 5e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CCC70729.1 - 5.8e-05 23.1 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 CCC70729.1 - 0.00021 20.9 0.0 0.0015 18.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 CCC70729.1 - 0.00023 20.7 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 CCC70729.1 - 0.00025 20.5 0.0 0.00038 19.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 CCC70729.1 - 0.0055 16.6 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 CCC70729.1 - 0.015 14.4 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 CCC70729.1 - 0.032 13.8 0.1 0.05 13.2 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.17 CCC70729.1 - 0.11 13.1 0.0 0.31 11.6 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_1 PF00667.20 CCC70730.1 - 4.1e-69 232.5 0.0 6.4e-69 231.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CCC70730.1 - 9.4e-31 106.9 0.7 1.6e-30 106.2 0.7 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CCC70730.1 - 2.7e-19 69.8 0.0 5.9e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MAGE PF01454.19 CCC70731.1 - 5.1e-43 147.3 0.6 7e-43 146.8 0.6 1.2 1 0 0 1 1 1 1 MAGE family Inositol_P PF00459.25 CCC70732.1 - 1.5e-73 247.7 0.0 1.6e-73 247.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Gamma-thionin PF00304.20 CCC70732.1 - 0.071 13.4 0.9 0.16 12.3 0.9 1.6 1 0 0 1 1 1 0 Gamma-thionin family DUF836 PF05768.14 CCC70733.1 - 1.6e-18 66.9 1.1 1.9e-18 66.6 1.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 CCC70733.1 - 0.0013 18.9 0.1 0.0038 17.4 0.1 1.8 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.6 CCC70733.1 - 0.0029 18.0 0.2 0.0036 17.7 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 CCC70733.1 - 0.052 13.4 0.0 0.067 13.0 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein PAP2 PF01569.21 CCC70735.1 - 2.7e-24 85.5 1.3 2.7e-24 85.5 1.3 1.6 2 0 0 2 2 2 1 PAP2 superfamily KdpA PF03814.15 CCC70735.1 - 0.002 16.4 0.1 0.0031 15.8 0.1 1.2 1 0 0 1 1 1 1 Potassium-transporting ATPase A subunit Choline_transpo PF04515.12 CCC70735.1 - 1.1 8.4 6.0 4.1 6.5 2.5 2.1 2 0 0 2 2 2 0 Plasma-membrane choline transporter HGTP_anticodon2 PF12745.7 CCC70736.1 - 1.5e-88 296.8 1.6 1.5e-88 296.8 1.6 2.9 4 0 0 4 4 4 1 Anticodon binding domain of tRNAs Pkinase PF00069.25 CCC70736.1 - 2.4e-68 230.3 0.7 5e-42 144.1 0.1 3.9 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70736.1 - 2.1e-33 115.7 0.1 5.5e-21 75.0 0.0 3.6 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 CCC70736.1 - 2.5e-19 69.7 0.5 1.5e-18 67.2 0.5 2.5 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.6 CCC70736.1 - 1.6e-13 50.7 0.0 4.8e-13 49.1 0.0 1.8 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.6 CCC70736.1 - 0.00091 18.6 0.0 0.97 8.7 0.0 2.5 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 CCC70736.1 - 0.0016 18.1 1.5 0.47 10.0 0.1 3.2 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCC70736.1 - 0.044 13.7 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3886 PF13025.6 CCC70736.1 - 6.2 7.1 13.1 22 5.3 13.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) CTD_bind PF04818.13 CCC70737.1 - 9.2e-18 64.8 0.1 2.5e-16 60.2 0.0 2.8 3 0 0 3 3 3 1 RNA polymerase II-binding domain. CTK3 PF12243.8 CCC70737.1 - 0.058 13.4 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 CDC45 PF02724.14 CCC70737.1 - 2.7 6.2 13.3 4.5 5.4 13.3 1.3 1 0 0 1 1 1 0 CDC45-like protein GLEYA PF10528.9 CCC70738.1 - 3.3e-57 190.9 24.7 6.4e-20 71.4 2.5 4.5 3 0 0 3 3 3 3 GLEYA domain PA14 PF07691.12 CCC70738.1 - 3.2e-33 114.6 4.2 3.1e-11 43.3 0.0 4.2 4 0 0 4 4 4 3 PA14 domain Flocculin PF00624.18 CCC70738.1 - 0.0027 17.9 21.4 0.0027 17.9 21.4 15.0 15 1 0 15 15 15 2 Flocculin repeat WW_like PF17890.1 CCC70738.1 - 0.013 15.6 6.6 8.8 6.5 0.2 4.3 3 0 0 3 3 3 0 Peptidoglycan hydrolase LytB WW-like domain DUF5060 PF16586.5 CCC70738.1 - 0.55 10.6 6.0 38 4.7 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF5060) GLEYA PF10528.9 CCC70739.1 - 3.1e-25 88.4 6.7 9.2e-18 64.5 3.7 3.2 2 0 0 2 2 2 2 GLEYA domain PA14 PF07691.12 CCC70739.1 - 4.5e-11 42.7 0.0 7.2e-08 32.4 0.0 2.6 2 0 0 2 2 2 2 PA14 domain Flocculin PF00624.18 CCC70739.1 - 0.0079 16.4 8.7 0.0079 16.4 8.7 9.5 11 0 0 11 11 11 3 Flocculin repeat Pyridoxal_deC PF00282.19 CCC70740.1 - 1.1e-20 73.7 0.0 2.3e-19 69.4 0.0 2.2 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 CCC70740.1 - 1e-06 28.3 0.0 1.6e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 CCC70740.1 - 7.3e-06 25.2 0.0 0.00034 19.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V RNB PF00773.19 CCC70741.1 - 4e-58 197.3 2.0 4e-58 197.3 2.0 1.9 2 0 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 CCC70741.1 - 4.6e-23 81.0 0.0 1.4e-22 79.5 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Dis3l2_C_term PF17877.1 CCC70741.1 - 3.1e-22 78.7 0.4 2.4e-21 75.9 0.0 2.6 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 CCC70741.1 - 9.7e-07 28.9 0.0 0.00033 20.8 0.0 3.1 3 0 0 3 3 3 1 Cold shock domain OB_RNB PF08206.11 CCC70741.1 - 0.0012 18.4 0.1 0.59 9.8 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease B OB domain Rrp44_CSD1 PF17216.3 CCC70741.1 - 0.0024 17.6 0.1 0.0081 15.9 0.1 1.9 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 CCC70741.1 - 0.11 12.5 0.0 0.43 10.6 0.0 2.0 1 0 0 1 1 1 0 S1 domain zf-HIT PF04438.16 CCC70742.1 - 1.6e-09 37.5 10.7 2.9e-09 36.6 10.7 1.5 1 0 0 1 1 1 1 HIT zinc finger PDDEXK_6 PF04720.12 CCC70742.1 - 0.027 14.4 1.4 0.05 13.6 0.8 1.7 2 0 0 2 2 2 0 PDDEXK-like family of unknown function zf-MYND PF01753.18 CCC70742.1 - 3.9 7.6 12.3 8.7 6.5 12.3 1.6 1 0 0 1 1 1 0 MYND finger zf-H2C2_2 PF13465.6 CCC70742.1 - 3.9 8.1 11.6 1.8 9.1 8.1 2.3 2 1 1 3 3 3 0 Zinc-finger double domain SRX PF09201.10 CCC70743.1 - 1.9e-62 209.5 3.4 5.3e-62 208.0 3.4 1.8 1 0 0 1 1 1 1 SRX, signal recognition particle receptor alpha subunit SRP54 PF00448.22 CCC70743.1 - 1.3e-47 162.0 0.2 4.5e-45 153.7 0.2 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 CCC70743.1 - 2.3e-06 27.7 0.3 7.7e-06 26.0 0.3 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 CCC70743.1 - 5.3e-05 22.3 0.0 0.00015 20.8 0.0 1.8 1 1 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ArsA_ATPase PF02374.15 CCC70743.1 - 0.0012 18.1 0.3 0.17 11.0 0.0 2.6 3 0 0 3 3 3 1 Anion-transporting ATPase cobW PF02492.19 CCC70743.1 - 0.0013 18.3 0.0 0.0032 17.1 0.0 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.23 CCC70743.1 - 0.0023 18.0 0.0 0.0061 16.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 CCC70743.1 - 0.0049 16.8 0.1 0.0049 16.8 0.1 3.2 3 1 0 3 3 3 1 AAA domain Fer4_NifH PF00142.18 CCC70743.1 - 0.0096 15.4 0.0 0.02 14.4 0.0 1.6 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_30 PF13604.6 CCC70743.1 - 0.026 14.3 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 CCC70743.1 - 5.8 6.9 8.6 1.3 9.0 0.3 3.4 4 0 0 4 4 4 0 Helicase HerA, central domain DEAD PF00270.29 CCC70744.1 - 3.6e-24 85.5 0.0 1.2e-23 83.7 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.10 CCC70744.1 - 3.5e-20 72.5 0.2 1.2e-19 70.8 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1998) Helicase_C PF00271.31 CCC70744.1 - 2.5e-14 53.6 0.1 1.4e-13 51.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC70744.1 - 1.1e-07 32.1 0.0 2.2e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 CCC70744.1 - 1.1e-06 29.0 0.7 2.9e-06 27.7 0.5 1.8 2 0 0 2 2 2 1 DNA replication factor CDT1 like GLEYA PF10528.9 CCC70746.1 - 1.1e-39 134.7 11.6 8.5e-20 71.0 4.6 3.6 2 0 0 2 2 2 2 GLEYA domain PA14 PF07691.12 CCC70746.1 - 8.2e-22 77.6 3.5 2.3e-10 40.4 0.0 3.6 3 1 1 4 4 4 2 PA14 domain OSCP PF00213.18 CCC70747.1 - 1.6e-37 129.3 3.7 1.9e-37 129.0 3.7 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit DUF1265 PF06887.14 CCC70747.1 - 0.15 12.0 0.3 0.67 10.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1265) Mhr1 PF12829.7 CCC70748.1 - 2.1e-22 79.0 0.9 3.9e-22 78.1 0.9 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF3105 PF11303.8 CCC70748.1 - 0.0042 17.2 0.0 0.055 13.6 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3105) Rad17 PF03215.15 CCC70748.1 - 0.046 13.6 0.1 0.96 9.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain HDA2-3 PF11496.8 CCC70749.1 - 1.4e-64 218.1 7.3 1.4e-64 218.1 7.3 2.2 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 AATF-Che1 PF13339.6 CCC70750.1 - 5.4e-26 91.9 5.2 5.4e-26 91.9 5.2 4.0 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 CCC70750.1 - 9.1e-24 83.8 0.1 9.1e-24 83.8 0.1 3.7 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AA_kinase PF00696.28 CCC70751.1 - 1.6e-36 126.2 0.7 8.2e-36 123.8 0.6 1.9 2 0 0 2 2 2 1 Amino acid kinase family PUA PF01472.20 CCC70751.1 - 2.7e-20 72.1 0.0 5.6e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 PUA domain CPSF_A PF03178.15 CCC70752.1 - 1.5e-89 300.5 0.2 1.9e-87 293.6 0.0 3.0 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.9 CCC70752.1 - 6.2e-15 54.8 5.7 7.4e-15 54.5 4.6 1.7 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RXT2_N PF08595.11 CCC70752.1 - 4.5 7.3 7.1 16 5.5 1.8 2.6 2 0 0 2 2 2 0 RXT2-like, N-terminal PIG-F PF06699.11 CCC70753.1 - 1.6e-26 93.6 21.1 2.4e-25 89.7 21.1 2.0 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F TauE PF01925.19 CCC70753.1 - 0.23 11.0 6.9 0.86 9.2 6.9 1.9 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE DUF3278 PF11683.8 CCC70753.1 - 1.6 8.8 4.9 0.77 9.9 2.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) Zn_clus PF00172.18 CCC70754.1 - 2.3e-07 30.8 8.1 4.3e-07 29.9 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.21 CCC70755.1 - 1.8e-30 106.3 0.0 2.3e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HIT PF01230.23 CCC70756.1 - 2.4e-08 34.6 0.2 7.2e-08 33.1 0.1 1.7 2 0 0 2 2 2 1 HIT domain CM1 PF03026.15 CCC70757.1 - 0.059 12.7 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Influenza C virus M1 protein LRR_5 PF13306.6 CCC70758.1 - 0.018 15.0 1.3 0.38 10.7 0.0 3.4 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) F-box-like PF12937.7 CCC70758.1 - 0.042 13.7 0.5 0.11 12.4 0.5 1.8 1 0 0 1 1 1 0 F-box-like PMT PF02366.18 CCC70759.1 - 1.2e-21 77.4 25.2 1.6e-21 77.1 22.8 2.0 1 1 1 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.19 CCC70759.1 - 1.2e-05 25.3 0.0 9.7e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 MIR domain Med21 PF11221.8 CCC70760.1 - 1.7e-45 154.8 4.4 2.1e-45 154.5 4.4 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF2200 PF09966.9 CCC70760.1 - 0.0003 20.9 0.1 0.031 14.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2200) Med9 PF07544.13 CCC70760.1 - 0.00047 20.2 2.2 0.00097 19.2 1.0 2.0 1 1 1 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 DUF1826 PF08856.11 CCC70760.1 - 0.16 11.9 0.2 0.38 10.7 0.1 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1826) FYVE PF01363.21 CCC70761.1 - 3.1e-18 65.7 11.4 3.1e-18 65.7 11.4 3.0 3 1 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.6 CCC70761.1 - 7.1e-08 32.7 2.8 7.1e-08 32.7 2.8 4.7 5 1 1 6 6 6 1 Ring finger domain zf-RING_11 PF17123.5 CCC70761.1 - 1.9e-06 27.5 5.2 1e-05 25.2 5.2 2.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 CCC70761.1 - 9.3e-05 22.4 2.1 9.3e-05 22.4 2.1 4.3 5 0 0 5 5 5 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CCC70761.1 - 0.00054 19.8 3.2 0.00054 19.8 3.2 5.1 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCC70761.1 - 0.001 18.9 3.4 0.001 18.9 3.4 4.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) RNF220 PF15926.5 CCC70761.1 - 0.0032 17.1 1.9 0.0032 17.1 1.9 2.1 1 1 1 2 2 2 1 E3 ubiquitin-protein ligase RNF220 zf-C3HC4_4 PF15227.6 CCC70761.1 - 0.043 14.0 1.4 0.043 14.0 1.4 4.7 5 1 0 5 5 5 0 zinc finger of C3HC4-type, RING Brix PF04427.18 CCC70762.1 - 1.1e-49 169.2 2.9 1.1e-49 169.2 2.9 1.6 2 0 0 2 2 2 1 Brix domain Cwf_Cwc_15 PF04889.12 CCC70762.1 - 5.9 6.6 30.7 5.1 6.8 14.4 2.4 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein DEAD PF00270.29 CCC70763.1 - 1.5e-48 164.9 0.0 2.6e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC70763.1 - 1.2e-29 102.9 0.0 1.2e-29 102.9 0.0 2.9 5 0 0 5 5 5 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC70763.1 - 4.2e-06 26.9 0.0 1.8e-05 24.8 0.0 2.0 1 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 CCC70763.1 - 0.011 16.1 0.0 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain GLTP PF08718.11 CCC70763.1 - 0.06 13.6 3.5 0.14 12.4 0.0 3.0 4 0 0 4 4 4 0 Glycolipid transfer protein (GLTP) RP-C_C PF11800.8 CCC70763.1 - 0.54 10.3 7.7 0.9 9.6 7.7 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Dsh_C PF12316.8 CCC70763.1 - 0.65 10.4 3.4 1 9.7 3.4 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Ins_P5_2-kin PF06090.12 CCC70766.1 - 2.2e-15 57.0 2.5 8e-15 55.1 2.5 1.8 1 1 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Methyltransf_23 PF13489.6 CCC70767.1 - 1.1e-22 80.6 0.0 1.9e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCC70767.1 - 1.3e-13 50.9 1.4 1.3e-09 37.7 0.2 2.5 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CCC70767.1 - 1.7e-13 51.2 0.1 3.3e-12 47.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCC70767.1 - 1.9e-11 44.5 0.0 8.7e-11 42.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC70767.1 - 2.1e-09 37.9 0.0 6.7e-08 33.1 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC70767.1 - 4.6e-09 36.2 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 CCC70767.1 - 0.089 12.2 1.4 1.3 8.4 0.0 2.6 2 1 1 3 3 3 0 Tellurite resistance protein TehB MttA_Hcf106 PF02416.16 CCC70767.1 - 0.13 11.6 0.1 0.3 10.5 0.1 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family Cyclin_N PF00134.23 CCC70768.1 - 3.1e-09 36.7 0.0 4.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCC70768.1 - 0.007 16.7 0.1 0.01 16.2 0.1 1.4 1 0 0 1 1 1 1 Cyclin CENP-O PF09496.10 CCC70769.1 - 1.8e-09 37.9 0.0 1.8e-09 37.9 0.0 2.3 2 1 0 2 2 2 1 Cenp-O kinetochore centromere component DivIC PF04977.15 CCC70769.1 - 0.032 14.0 0.6 0.032 14.0 0.6 2.9 3 0 0 3 3 3 0 Septum formation initiator YqfQ PF14181.6 CCC70769.1 - 0.29 11.3 5.0 0.16 12.2 2.9 1.6 1 1 0 1 1 1 0 YqfQ-like protein Scs3p PF10261.9 CCC70770.1 - 1.7e-19 70.3 16.1 8.4e-12 45.1 5.8 2.8 1 1 1 2 2 2 2 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.21 CCC70770.1 - 0.002 17.9 1.8 0.0073 16.1 1.6 2.1 1 1 1 2 2 2 1 PAP2 superfamily Ubiq-assoc PF09145.10 CCC70771.1 - 1.6e-24 85.6 1.6 1.6e-24 85.6 1.6 2.0 2 0 0 2 2 2 1 Ubiquitin-associated TPR_1 PF00515.28 CCC70771.1 - 0.021 14.7 0.6 7.6 6.5 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 CCC70771.1 - 0.03 14.4 0.1 3.1 8.1 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCC70771.1 - 0.072 13.4 0.0 0.44 10.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DASH_Dad4 PF08650.10 CCC70772.1 - 6.2e-33 112.6 8.7 6.8e-33 112.5 8.7 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 TMF_TATA_bd PF12325.8 CCC70772.1 - 0.017 15.4 0.7 0.02 15.1 0.7 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding NPV_P10 PF05531.12 CCC70772.1 - 0.027 14.9 0.6 0.032 14.7 0.6 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF3251 PF11622.8 CCC70772.1 - 0.056 13.1 0.3 0.059 13.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) HU-CCDC81_bac_2 PF18175.1 CCC70772.1 - 0.074 12.9 1.3 0.12 12.3 1.3 1.3 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 2 DUF4047 PF13256.6 CCC70772.1 - 0.094 12.9 3.0 0.31 11.2 3.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) DASH_Dad1 PF08649.10 CCC70772.1 - 0.3 11.3 6.9 5.1 7.4 6.9 2.1 1 1 0 1 1 1 0 DASH complex subunit Dad1 Asparaginase PF00710.20 CCC70773.1 - 9.6e-56 188.4 0.0 7e-55 185.5 0.0 1.9 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 CCC70773.1 - 3.6e-19 69.1 0.0 7.6e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ribosomal_L19 PF01245.20 CCC70773.1 - 0.0096 15.8 0.0 2.1 8.3 0.0 3.0 3 0 0 3 3 3 1 Ribosomal protein L19 HMG_box PF00505.19 CCC70774.1 - 5e-06 26.8 12.3 1.2e-05 25.6 0.6 3.9 3 1 0 3 3 3 2 HMG (high mobility group) box ATP-synt_E PF05680.12 CCC70776.1 - 8.4e-13 48.5 0.0 9.3e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 ATP synthase E chain FYVE PF01363.21 CCC70777.1 - 2.2e-21 75.8 24.7 1.9e-17 63.1 2.1 3.3 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.8 CCC70777.1 - 1.7e-17 62.8 0.2 3.6e-17 61.8 0.2 1.6 1 0 0 1 1 1 1 Rabenosyn Rab binding domain zf-C2H2_6 PF13912.6 CCC70777.1 - 0.0031 17.5 0.4 0.0031 17.5 0.4 4.4 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CCC70777.1 - 0.0032 18.2 0.5 0.0032 18.2 0.5 5.3 5 1 1 6 6 6 1 C2H2-type zinc finger zf-Di19 PF05605.12 CCC70777.1 - 0.005 17.1 0.2 0.005 17.1 0.2 2.2 2 1 1 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding FYVE_2 PF02318.16 CCC70777.1 - 0.012 15.8 0.3 0.012 15.8 0.3 3.3 2 1 0 3 3 3 0 FYVE-type zinc finger FOXP-CC PF16159.5 CCC70777.1 - 0.021 15.4 0.2 0.07 13.8 0.2 1.9 1 0 0 1 1 1 0 FOXP coiled-coil domain IBR PF01485.21 CCC70777.1 - 0.023 14.9 4.3 0.023 14.9 4.3 4.1 4 0 0 4 4 4 0 IBR domain, a half RING-finger domain UBZ_FAAP20 PF15750.5 CCC70777.1 - 0.16 12.0 0.7 2.5 8.1 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin-binding zinc-finger Med27 PF11571.8 CCC70777.1 - 2.9 8.3 6.7 1.9 8.9 0.8 3.1 2 1 0 2 2 2 0 Mediator complex subunit 27 WD40 PF00400.32 CCC70778.1 - 1.3e-11 44.9 13.5 0.59 11.1 0.1 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC70778.1 - 2.3e-07 31.0 5.7 0.0059 16.9 0.3 6.4 4 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 CCC70778.1 - 0.008 15.2 0.8 0.42 9.5 0.1 2.7 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cnd3 PF12719.7 CCC70779.1 - 4.5e-93 311.6 3.1 4.5e-93 311.6 3.1 2.4 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 CCC70779.1 - 1.6e-09 38.0 0.0 4e-05 23.9 0.0 3.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 CCC70779.1 - 2.3e-06 27.4 0.4 0.2 12.0 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.7 CCC70779.1 - 1.4e-05 25.2 2.4 0.0003 20.9 0.1 4.1 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 CCC70779.1 - 0.015 15.8 0.0 0.69 10.5 0.0 3.2 2 1 1 3 3 3 0 HEAT-like repeat DUF4042 PF13251.6 CCC70779.1 - 0.016 14.9 0.5 0.92 9.2 0.1 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4042) CAP_N PF01213.19 CCC70779.1 - 0.038 13.5 2.6 0.3 10.5 0.2 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF1643 PF07799.12 CCC70779.1 - 0.064 13.4 0.0 0.29 11.3 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1643) DUF5610 PF18433.1 CCC70779.1 - 0.13 12.8 0.1 0.13 12.8 0.1 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5610) Vac14_Fab1_bd PF12755.7 CCC70779.1 - 0.3 11.7 2.2 2.1 9.0 0.3 3.2 2 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region VASt PF16016.5 CCC70780.1 - 1.4e-73 246.4 2.7 7e-37 127.2 0.0 3.0 2 0 0 2 2 2 2 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CCC70780.1 - 2.9e-26 91.6 0.0 6.9e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Sarcoglycan_1 PF04790.13 CCC70780.1 - 0.26 10.6 4.1 0.21 10.9 0.8 2.2 2 0 0 2 2 2 0 Sarcoglycan complex subunit protein Skp1 PF01466.19 CCC70781.1 - 1.3e-24 86.0 0.1 1.3e-24 86.0 0.1 2.3 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 CCC70781.1 - 3.3e-15 56.0 0.5 2.2e-07 31.0 0.2 2.5 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain DNA_pol_phi PF04931.13 CCC70781.1 - 3.3 5.7 11.5 3.9 5.5 11.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peroxin-3 PF04882.12 CCC70782.1 - 2.9e-87 293.6 19.0 7.6e-73 246.1 12.1 2.0 1 1 1 2 2 2 2 Peroxin-3 Nnf1 PF03980.14 CCC70782.1 - 0.0011 19.3 1.5 0.0047 17.3 0.2 2.6 2 1 0 2 2 2 1 Nnf1 SUIM_assoc PF16619.5 CCC70782.1 - 0.0029 17.6 0.2 0.0078 16.3 0.2 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Nrf1_DNA-bind PF10491.9 CCC70782.1 - 0.011 15.4 0.2 0.022 14.5 0.2 1.4 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 Thioredoxin_7 PF13899.6 CCC70783.1 - 7e-23 80.6 0.0 1.5e-22 79.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 CCC70783.1 - 1.4e-15 57.2 0.0 3e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 CCC70783.1 - 2.9e-14 52.6 1.5 6.5e-14 51.5 1.5 1.6 1 0 0 1 1 1 1 UBA-like domain C2-set PF05790.15 CCC70783.1 - 9.7e-05 22.5 0.1 0.00024 21.2 0.1 1.6 1 0 0 1 1 1 1 Immunoglobulin C2-set domain Na_trans_assoc PF06512.13 CCC70783.1 - 0.0014 18.9 1.3 0.0014 18.9 1.3 2.2 2 0 0 2 2 2 1 Sodium ion transport-associated Thioredox_DsbH PF03190.15 CCC70783.1 - 0.0072 16.3 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 CDC45 PF02724.14 CCC70783.1 - 0.92 7.7 10.1 0.29 9.4 1.6 2.2 2 0 0 2 2 2 0 CDC45-like protein Spt5_N PF11942.8 CCC70783.1 - 6.5 7.8 25.6 0.96 10.5 6.4 3.2 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal Peptidase_C13 PF01650.18 CCC70784.1 - 6e-47 160.3 1.2 8.7e-47 159.8 1.2 1.2 1 0 0 1 1 1 1 Peptidase C13 family CPSase_L_D3 PF02787.19 CCC70784.1 - 0.017 15.4 0.2 41 4.5 0.0 3.3 3 0 0 3 3 3 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ResIII PF04851.15 CCC70785.1 - 4.5e-27 95.1 0.2 2.4e-26 92.7 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCC70785.1 - 4.1e-13 49.5 0.1 1.3e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC70785.1 - 1e-12 48.4 1.7 2.1e-10 40.9 0.1 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 CCC70785.1 - 1.3e-07 31.6 0.1 2.9e-07 30.4 0.1 1.7 1 1 0 1 1 1 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 CCC70785.1 - 0.00077 19.7 0.0 0.0034 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain Peptidase_C23 PF05379.11 CCC70785.1 - 0.0054 16.8 0.0 0.75 10.0 0.0 3.5 4 0 0 4 4 4 1 Carlavirus endopeptidase DUF2075 PF09848.9 CCC70785.1 - 0.028 13.6 0.0 0.078 12.2 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNR_N PF08343.10 CCC70785.1 - 0.68 10.0 0.0 0.68 10.0 0.0 3.0 4 0 0 4 4 4 0 Ribonucleotide reductase N-terminal STE PF02200.16 CCC70786.1 - 1.4e-59 199.3 2.2 2.2e-59 198.6 2.2 1.3 1 0 0 1 1 1 1 STE like transcription factor Tcf25 PF04910.14 CCC70787.1 - 3.7e-81 272.9 0.1 3.7e-81 272.9 0.1 1.6 2 0 0 2 2 2 1 Transcriptional repressor TCF25 MRPL52 PF18699.1 CCC70787.1 - 0.11 12.7 6.8 0.34 11.1 6.8 1.8 1 0 0 1 1 1 0 Mitoribosomal protein mL52 ARD PF03079.14 CCC70787.1 - 0.2 11.8 7.6 0.6 10.3 7.6 1.8 1 0 0 1 1 1 0 ARD/ARD' family CCDC106 PF15794.5 CCC70787.1 - 0.21 11.3 12.1 0.49 10.1 12.1 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 SR-25 PF10500.9 CCC70787.1 - 0.38 10.3 10.8 0.7 9.5 10.8 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Rotamase PF00639.21 CCC70787.1 - 2.4 9.2 7.0 4.3 8.4 4.5 2.6 3 0 0 3 3 3 0 PPIC-type PPIASE domain Ipi1_N PF12333.8 CCC70788.1 - 1.6e-24 86.4 0.1 1.6e-24 86.4 0.1 2.5 3 1 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.22 CCC70788.1 - 0.064 13.5 0.3 5.7 7.5 0.0 3.3 3 0 0 3 3 3 0 HEAT repeat DUF2937 PF11157.8 CCC70788.1 - 0.068 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Gln-synt_C-ter PF18318.1 CCC70788.1 - 0.19 11.6 1.1 4.4 7.2 0.0 3.3 4 0 0 4 4 4 0 Glutamine synthetase C-terminal domain SNF2_N PF00176.23 CCC70789.1 - 8.6e-67 225.3 0.3 1.9e-66 224.2 0.3 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCC70789.1 - 1.3e-18 67.4 0.1 1.1e-17 64.3 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 CCC70789.1 - 8.6e-14 51.6 3.8 8.6e-14 51.6 3.8 2.8 1 1 1 2 2 2 1 HSA ResIII PF04851.15 CCC70789.1 - 2.1e-11 44.1 0.0 2.1e-11 44.1 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 CCC70789.1 - 3.6e-07 30.1 0.0 2e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase MMR_HSR1 PF01926.23 CCC70790.1 - 6.9e-16 58.4 0.0 1.3e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCC70790.1 - 9.5e-08 32.1 0.0 3.3e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 CCC70790.1 - 0.00014 21.4 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CCC70790.1 - 0.00037 20.6 0.0 0.21 11.6 0.0 2.6 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.27 CCC70790.1 - 0.0005 19.7 0.1 0.0078 15.8 0.1 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CCC70790.1 - 0.00085 18.8 0.0 0.0014 18.1 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 CCC70790.1 - 0.013 15.2 0.0 0.036 13.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AIG1 PF04548.16 CCC70790.1 - 0.022 14.1 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_23 PF13476.6 CCC70790.1 - 0.039 14.4 0.1 0.06 13.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 CCC70790.1 - 0.096 13.2 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter IIGP PF05049.13 CCC70790.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ribosomal_S15 PF00312.22 CCC70791.1 - 7.2e-32 109.4 0.6 1.7e-31 108.3 0.6 1.6 1 0 0 1 1 1 1 Ribosomal protein S15 MatE PF01554.18 CCC70792.1 - 2.7e-61 205.9 34.2 1.4e-38 132.1 8.2 2.7 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 CCC70792.1 - 0.0024 18.0 13.5 0.0024 18.0 13.5 3.1 3 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Fcf1 PF04900.12 CCC70793.1 - 5.6e-34 116.5 0.5 8.3e-34 115.9 0.1 1.4 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 CCC70793.1 - 1.3e-13 51.3 0.0 2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 PIN like domain Imm-NTF2 PF15655.6 CCC70793.1 - 0.081 13.2 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 NTF2 fold immunity protein Sugar_tr PF00083.24 CCC70794.1 - 1.4e-173 577.9 34.7 1.7e-173 577.7 34.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC70794.1 - 5.1e-28 98.0 29.0 1.2e-27 96.8 19.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CCC70794.1 - 1.1 7.6 6.6 0.43 8.9 3.8 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector DUF4293 PF14126.6 CCC70794.1 - 1.5 9.1 5.2 1.1 9.5 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Sugar_tr PF00083.24 CCC70795.1 - 1.8e-171 571.0 33.2 2e-171 570.8 33.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC70795.1 - 3.4e-31 108.4 32.3 4.9e-30 104.7 24.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Svf1 PF08622.10 CCC70796.1 - 1.2e-69 233.5 0.6 2e-69 232.8 0.6 1.3 1 0 0 1 1 1 1 Svf1-like N-terminal lipocalin domain Svf1_C PF17187.4 CCC70796.1 - 4e-64 215.4 0.3 7.8e-64 214.5 0.3 1.5 1 0 0 1 1 1 1 Svf1-like C-terminal lipocalin-like domain BUD22 PF09073.10 CCC70796.1 - 0.0012 18.3 6.8 0.0017 17.8 6.8 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.12 CCC70796.1 - 0.061 11.5 11.9 0.081 11.1 11.9 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 CCC70796.1 - 0.11 10.8 8.8 0.14 10.4 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 CCC70796.1 - 0.16 11.7 13.2 0.24 11.1 13.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Zip PF02535.22 CCC70796.1 - 0.17 11.1 3.0 0.29 10.3 3.0 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 CCC70796.1 - 0.47 9.2 5.6 0.66 8.7 5.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Coilin_N PF15862.5 CCC70796.1 - 0.58 10.0 6.3 0.11 12.2 2.9 1.6 2 0 0 2 2 2 0 Coilin N-terminus Presenilin PF01080.17 CCC70796.1 - 0.84 8.3 6.7 1.5 7.5 6.7 1.3 1 0 0 1 1 1 0 Presenilin SDA1 PF05285.12 CCC70796.1 - 1.1 8.7 15.6 1.6 8.1 15.6 1.2 1 0 0 1 1 1 0 SDA1 RNA_pol_Rpc4 PF05132.14 CCC70796.1 - 1.3 9.4 5.1 2.4 8.6 5.1 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 PPL5 PF18168.1 CCC70796.1 - 5.7 6.1 7.1 9.1 5.5 7.1 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Sod_Fe_C PF02777.18 CCC70797.1 - 1.1e-13 51.2 1.1 4.4e-06 26.8 0.1 2.5 2 1 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Pal1 PF08316.11 CCC70798.1 - 6.2e-51 172.8 2.8 6.2e-51 172.8 2.8 3.3 2 2 1 3 3 3 1 Pal1 cell morphology protein Asp PF00026.23 CCC70799.1 - 1.1e-20 74.3 0.4 1.1e-20 74.3 0.4 3.0 3 1 0 3 3 3 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 CCC70799.1 - 0.00021 21.5 2.8 0.00095 19.4 0.3 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DUF4437 PF14499.6 CCC70799.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4437) FAT PF02259.23 CCC70800.1 - 1.9e-70 237.8 7.6 6.3e-70 236.1 7.6 2.0 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 CCC70800.1 - 1.8e-48 165.5 1.4 1.8e-48 165.5 1.4 2.8 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 CCC70800.1 - 6.7e-06 25.8 0.0 1.7e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 CCC70800.1 - 0.058 13.7 0.2 1.2 9.6 0.1 3.3 2 0 0 2 2 2 0 HEAT repeat NDUF_B7 PF05676.13 CCC70800.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) SBE2 PF17076.5 CCC70802.1 - 1.7e-220 734.5 36.0 2.9e-220 733.7 36.0 1.3 1 0 0 1 1 1 1 SBE2, cell-wall formation PQ-loop PF04193.14 CCC70803.1 - 6e-36 122.0 9.5 2.7e-18 65.5 1.2 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 CCC70803.1 - 0.08 13.0 8.1 0.13 12.3 0.2 3.4 2 2 1 3 3 3 0 Sugar efflux transporter for intercellular exchange DUF5090 PF17009.5 CCC70803.1 - 1.3 9.0 5.0 3.8 7.4 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Pyr_redox_2 PF07992.14 CCC70804.1 - 4.4e-51 173.8 0.2 5.1e-51 173.6 0.2 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCC70804.1 - 1.9e-20 73.2 0.2 4.9e-17 62.3 0.0 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCC70804.1 - 3e-14 53.0 0.1 6.4e-12 45.3 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCC70804.1 - 1.3e-05 24.5 0.7 0.58 9.2 0.1 3.9 4 0 0 4 4 4 2 Glucose inhibited division protein A NAD_binding_7 PF13241.6 CCC70804.1 - 0.00013 22.4 0.0 0.043 14.3 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 CCC70804.1 - 0.00032 20.0 0.0 0.0022 17.3 0.0 2.1 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 CCC70804.1 - 0.00042 20.5 0.0 0.032 14.5 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 CCC70804.1 - 0.002 17.4 0.2 0.93 8.6 0.0 3.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 CCC70804.1 - 0.0064 16.5 0.1 3.4 7.7 0.0 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.19 CCC70804.1 - 0.0096 15.2 0.1 2.5 7.2 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 CCC70804.1 - 0.015 14.4 1.5 2 7.4 0.2 2.8 2 2 1 3 3 3 0 FAD binding domain DAO PF01266.24 CCC70804.1 - 0.054 13.1 0.4 3.4 7.2 0.0 2.5 1 1 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.14 CCC70804.1 - 0.067 11.9 0.3 1.8 7.2 0.2 2.6 2 1 1 3 3 3 0 HI0933-like protein Glycos_transf_3 PF00591.21 CCC70805.1 - 4.5e-83 278.7 0.0 5.7e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 CCC70805.1 - 1.2e-12 47.5 0.0 2.1e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain Spc110_C PF18520.1 CCC70806.1 - 1.9e-24 85.0 4.5 1.9e-24 85.0 4.5 2.5 2 0 0 2 2 2 1 Spindle pole body component 110 C-terminal domain GAS PF13851.6 CCC70806.1 - 0.0011 18.4 10.7 0.0011 18.4 10.7 8.3 2 2 6 8 8 8 1 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 CCC70806.1 - 0.0049 17.1 10.3 0.0049 17.1 10.3 8.5 3 2 4 7 7 7 1 Domain of unknown function (DUF5082) PACT_coil_coil PF10495.9 CCC70806.1 - 0.012 16.2 0.1 0.012 16.2 0.1 4.1 4 1 0 4 4 4 0 Pericentrin-AKAP-450 domain of centrosomal targeting protein DUF4337 PF14235.6 CCC70806.1 - 0.015 15.4 1.5 0.015 15.4 1.5 7.9 2 2 5 8 8 8 0 Domain of unknown function (DUF4337) NMO PF03060.15 CCC70806.1 - 0.45 9.9 2.4 0.76 9.1 1.2 2.1 1 1 0 1 1 1 0 Nitronate monooxygenase DASH_Dam1 PF08653.10 CCC70807.1 - 0.13 12.1 2.6 2.6 7.9 0.5 2.3 1 1 1 2 2 2 0 DASH complex subunit Dam1 VHS PF00790.19 CCC70808.1 - 1.9e-48 163.9 0.1 1.1e-47 161.5 0.0 2.2 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 CCC70808.1 - 1e-21 77.0 1.6 4.6e-21 74.9 1.6 2.2 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.20 CCC70808.1 - 9.8e-21 74.2 0.4 2.3e-20 72.9 0.1 1.9 2 0 0 2 2 2 1 Adaptin C-terminal domain GGA_N-GAT PF18308.1 CCC70808.1 - 3.4e-07 29.8 4.8 5.9e-06 25.8 0.4 2.6 2 0 0 2 2 2 2 GGA N-GAT domain Herpes_capsid PF06112.11 CCC70808.1 - 6.5 6.8 6.2 30 4.6 4.2 2.4 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein HSA PF07529.13 CCC70809.1 - 9e-14 51.5 0.0 9e-14 51.5 0.0 3.2 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.6 CCC70809.1 - 5.8e-09 36.1 0.3 1.9e-08 34.5 0.3 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 CCC70809.1 - 0.0003 20.9 0.1 0.00088 19.4 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain BCIP PF13862.6 CCC70810.1 - 4.1e-48 163.9 0.3 6.6e-48 163.2 0.3 1.3 1 0 0 1 1 1 1 p21-C-terminal region-binding protein RPN2_C PF18004.1 CCC70810.1 - 0.013 15.4 0.2 0.013 15.4 0.2 1.8 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN2 C-terminal domain ThiF PF00899.21 CCC70811.1 - 3.2e-61 206.8 0.0 4.6e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 CCC70811.1 - 2.3e-11 44.2 0.0 6.1e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.20 CCC70811.1 - 0.0014 18.7 0.0 0.0036 17.4 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Herpes_BLRF2 PF05812.12 CCC70811.1 - 0.021 15.0 0.6 0.038 14.1 0.2 1.6 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein MscS_porin PF12795.7 CCC70811.1 - 0.09 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain WD40 PF00400.32 CCC70812.1 - 0.91 10.5 3.4 46 5.1 0.1 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat Cys_Met_Meta_PP PF01053.20 CCC70813.1 - 3.9e-68 229.7 0.0 1.1e-67 228.2 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 CCC70813.1 - 6.9e-06 25.3 0.0 9.6e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V gag_pre-integrs PF13976.6 CCC70813.1 - 0.14 12.1 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain TMEM51 PF15345.6 CCC70814.1 - 0.00019 21.4 0.2 0.00023 21.1 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 O-antigen_lig PF13425.6 CCC70814.1 - 0.02 13.7 0.0 0.025 13.4 0.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Endomucin PF07010.12 CCC70814.1 - 0.028 14.4 0.3 0.036 14.1 0.3 1.2 1 0 0 1 1 1 0 Endomucin Chordopox_A33R PF05966.12 CCC70814.1 - 0.032 13.5 0.1 0.047 13.0 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus A33R protein SID-1_RNA_chan PF13965.6 CCC70814.1 - 0.036 12.5 0.1 0.045 12.2 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Comm PF15957.5 CCC70814.1 - 0.063 13.6 0.8 0.12 12.7 0.8 1.7 1 1 0 1 1 1 0 Commissureless MASE4 PF17158.4 CCC70814.1 - 0.14 11.4 0.0 0.19 11.0 0.0 1.1 1 0 0 1 1 1 0 Membrane-associated sensor, integral membrane domain ETRAMP PF09716.10 CCC70814.1 - 0.15 12.2 0.1 0.32 11.1 0.0 1.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Rad60-SLD PF11976.8 CCC70815.1 - 5.1e-26 90.3 2.7 1.9e-25 88.4 1.0 2.7 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 CCC70815.1 - 0.07 12.9 0.7 0.16 11.7 0.2 2.0 2 0 0 2 2 2 0 Ubiquitin family DUF2541 PF10807.8 CCC70815.1 - 0.1 12.7 0.1 0.33 11.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2541) DSS1_SEM1 PF05160.13 CCC70816.1 - 3.6e-20 71.8 17.1 6e-20 71.1 17.1 1.3 1 0 0 1 1 1 1 DSS1/SEM1 family AAA PF00004.29 CCC70817.1 - 1.5e-41 141.9 0.0 3.7e-41 140.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 CCC70817.1 - 1.9e-21 75.7 0.2 4.2e-21 74.7 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 CCC70817.1 - 6.2e-09 35.5 0.0 1.6e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 CCC70817.1 - 8.1e-06 26.1 0.0 0.00021 21.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 CCC70817.1 - 1.4e-05 25.5 0.1 0.012 15.9 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_5 PF07728.14 CCC70817.1 - 6.5e-05 23.0 1.6 0.0002 21.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 CCC70817.1 - 0.00075 19.3 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 CCC70817.1 - 0.0017 18.5 0.1 0.024 14.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCC70817.1 - 0.0023 18.2 2.3 0.043 14.1 0.4 2.8 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 CCC70817.1 - 0.0059 16.1 0.2 0.064 12.7 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.21 CCC70817.1 - 0.013 14.8 0.1 0.036 13.4 0.1 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.13 CCC70817.1 - 0.021 14.0 0.0 0.04 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 CCC70817.1 - 0.023 14.4 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 CCC70817.1 - 0.043 13.6 0.8 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 CCC70817.1 - 0.048 14.0 0.6 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain ThylakoidFormat PF11264.8 CCC70817.1 - 0.08 12.6 2.7 0.17 11.5 2.7 1.5 1 0 0 1 1 1 0 Thylakoid formation protein AAA_7 PF12775.7 CCC70817.1 - 0.087 12.3 0.0 0.2 11.2 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 CCC70817.1 - 0.099 13.0 0.1 0.65 10.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 CCC70817.1 - 0.1 12.3 0.9 0.32 10.7 0.1 2.3 2 1 0 2 2 2 0 AAA domain ATPase PF06745.13 CCC70817.1 - 0.31 10.3 2.3 0.41 10.0 0.0 2.2 3 0 0 3 3 3 0 KaiC TolA_bind_tri PF16331.5 CCC70817.1 - 0.98 9.5 7.9 1.3 9.2 4.9 2.4 2 0 0 2 2 2 0 TolA binding protein trimerisation WD40 PF00400.32 CCC70818.1 - 2.7e-32 110.3 10.1 6.8e-09 36.2 0.5 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC70818.1 - 5.6e-12 45.8 0.0 0.0056 17.0 0.0 4.4 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain NUC153 PF08159.12 CCC70819.1 - 8.7e-13 47.8 13.3 3e-12 46.1 4.7 3.2 3 0 0 3 3 3 2 NUC153 domain RIO1 PF01163.22 CCC70820.1 - 5.5e-74 247.9 2.4 5.5e-74 247.9 2.4 2.9 3 0 0 3 3 3 1 RIO1 family Pkinase PF00069.25 CCC70820.1 - 0.00063 19.2 3.3 0.00082 18.8 0.4 2.7 3 0 0 3 3 3 1 Protein kinase domain APH PF01636.23 CCC70820.1 - 0.0046 16.9 0.0 0.83 9.5 0.0 2.5 2 0 0 2 2 2 2 Phosphotransferase enzyme family DUF4135 PF13575.6 CCC70820.1 - 0.013 14.9 0.3 0.04 13.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4135) Kei1 PF08552.11 CCC70821.1 - 1.3e-41 142.6 15.8 3.6e-34 118.3 9.4 2.1 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 Jiraiya PF15038.6 CCC70821.1 - 1.4 8.3 8.1 0.047 13.1 0.7 2.1 1 1 1 2 2 2 0 Jiraiya Aldo_ket_red PF00248.21 CCC70822.1 - 8.6e-41 140.0 0.0 1.2e-38 133.0 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family FHA PF00498.26 CCC70823.1 - 3.6e-06 27.2 0.4 1.4e-05 25.4 0.4 2.1 1 0 0 1 1 1 1 FHA domain RAI1 PF08652.11 CCC70824.1 - 0.00046 20.3 0.2 0.0017 18.5 0.0 2.0 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease YCII PF03795.14 CCC70825.1 - 1.5e-06 28.5 0.0 1.9e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain GPP34 PF05719.11 CCC70827.1 - 1.4e-65 221.2 0.0 1.7e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) EF-hand_1 PF00036.32 CCC70828.1 - 1.2e-26 90.2 6.1 2.1e-07 30.0 0.4 4.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 CCC70828.1 - 2.5e-23 82.3 5.7 2.9e-16 59.7 0.4 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCC70828.1 - 6.4e-23 78.7 7.0 4.9e-06 26.1 0.1 5.0 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 CCC70828.1 - 4.4e-22 77.7 7.1 2.4e-11 43.3 0.0 3.7 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 CCC70828.1 - 6e-18 63.5 3.3 8.6e-05 21.9 0.3 4.3 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 CCC70828.1 - 5.4e-05 23.1 3.6 2.1 8.3 0.1 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 CCC70828.1 - 0.00014 22.1 0.4 0.023 15.0 0.1 2.7 1 1 1 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 CCC70828.1 - 0.00039 20.7 1.1 0.13 12.6 0.2 3.2 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Acyltransferase PF01553.21 CCC70829.1 - 0.0076 15.9 0.0 0.032 13.8 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.21 CCC70830.1 - 3.5e-14 52.6 0.0 5.5e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Kinesin PF00225.23 CCC70831.1 - 2.1e-103 345.8 3.2 2.1e-103 345.8 3.2 2.5 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CCC70831.1 - 2.5e-56 189.8 0.3 2.5e-56 189.8 0.3 3.7 4 2 1 5 5 5 1 Microtubule binding Spc7 PF08317.11 CCC70831.1 - 2.6 6.8 61.8 0.65 8.8 6.2 3.4 1 1 2 3 3 3 0 Spc7 kinetochore protein LRRFIP PF09738.9 CCC70831.1 - 9.1 5.7 57.4 0.89 9.0 35.2 2.5 1 1 1 2 2 2 0 LRRFIP family Rrp15p PF07890.12 CCC70832.1 - 1.2e-30 106.6 13.9 1.2e-30 106.6 13.9 2.3 2 1 0 2 2 2 1 Rrp15p Ndc1_Nup PF09531.10 CCC70832.1 - 0.51 9.0 6.2 0.58 8.8 6.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Metallophos PF00149.28 CCC70833.1 - 2.7e-34 119.5 0.1 4.8e-34 118.6 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 CCC70833.1 - 3.9e-23 81.6 0.4 2.1e-22 79.2 0.1 2.1 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 CCC70833.1 - 6.9e-14 51.0 3.0 2e-08 33.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 CCC70833.1 - 2.1e-12 46.1 0.1 7.7e-05 22.5 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCC70833.1 - 2.3e-12 46.4 1.7 4.7e-08 32.6 0.1 3.2 3 0 0 3 3 3 2 TPR repeat TPR_9 PF13371.6 CCC70833.1 - 2e-07 31.0 0.2 4.5e-05 23.5 0.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCC70833.1 - 3e-06 27.2 1.0 0.053 13.9 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCC70833.1 - 2.3e-05 24.2 0.5 0.0077 16.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 CCC70833.1 - 0.00027 21.4 0.5 0.0092 16.5 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCC70833.1 - 0.012 15.6 1.9 0.18 11.9 0.0 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 CCC70833.1 - 0.012 16.2 0.0 0.63 10.7 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TFIIB PF00382.19 CCC70833.1 - 0.015 15.3 0.0 0.033 14.2 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat TPR_7 PF13176.6 CCC70833.1 - 0.021 14.8 0.1 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCC70833.1 - 0.045 14.6 0.2 12 7.1 0.0 3.4 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCC70833.1 - 0.08 13.6 0.7 11 6.9 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 CCC70833.1 - 0.084 13.2 0.6 0.49 10.7 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 CCC70833.1 - 0.088 12.9 0.5 0.24 11.5 0.5 1.8 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.6 CCC70833.1 - 0.24 10.6 0.4 12 5.0 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat CBF PF03914.17 CCC70834.1 - 1.5e-33 116.2 2.0 3.9e-33 114.9 2.0 1.8 1 0 0 1 1 1 1 CBF/Mak21 family AHD PF17793.1 CCC70834.1 - 0.12 12.2 2.5 0.56 10.0 2.5 2.2 1 1 0 1 1 1 0 ANC1 homology domain (AHD) Asn_synthase PF00733.21 CCC70835.1 - 6.1e-95 318.9 0.7 1.3e-54 186.2 0.1 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 CCC70835.1 - 2.9e-35 120.8 0.0 4.7e-35 120.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 CCC70835.1 - 6.8e-28 97.5 0.0 1.2e-27 96.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 CCC70835.1 - 2.8e-06 26.9 0.0 6e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 CCC70835.1 - 0.027 13.6 0.0 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 NAD synthase LIDHydrolase PF10230.9 CCC70837.1 - 4.9e-69 232.8 1.3 5.6e-69 232.6 1.3 1.0 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 CCC70837.1 - 0.018 14.9 0.2 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) BAR_2 PF10455.9 CCC70838.1 - 6e-82 275.0 54.4 3.6e-79 265.9 54.4 3.3 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.18 CCC70838.1 - 0.00017 21.3 5.5 0.00017 21.3 5.5 4.1 3 2 0 4 4 4 2 BAR domain Herpes_UL6 PF01763.16 CCC70838.1 - 2.7 6.4 14.1 0.074 11.6 5.5 2.4 2 1 1 3 3 3 0 Herpesvirus UL6 like Cytochrom_C PF00034.21 CCC70839.1 - 0.52 11.5 0.1 0.52 11.5 0.1 3.1 2 1 0 2 2 2 0 Cytochrome c Sulfotransfer_4 PF17784.1 CCC70839.1 - 3.5 7.4 6.5 4 7.2 2.7 2.2 1 1 1 2 2 2 0 Sulfotransferase domain MARVEL PF01284.23 CCC70840.1 - 4.4e-24 85.2 16.1 5.6e-24 84.8 16.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF4345 PF14248.6 CCC70840.1 - 0.0083 16.0 0.4 0.0083 16.0 0.4 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4345) Pet20 PF08692.10 CCC70841.1 - 4e-26 92.2 5.8 3.3e-17 63.4 0.3 3.0 2 1 1 3 3 3 2 Mitochondrial protein Pet20 Bac_small_YrzI PF09501.10 CCC70841.1 - 2.6 8.3 6.6 2.7 8.2 0.4 2.5 2 0 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) WW PF00397.26 CCC70842.1 - 2.3e-09 37.2 5.0 2.3e-09 37.2 5.0 2.4 3 0 0 3 3 3 1 WW domain FF PF01846.19 CCC70842.1 - 3.7e-06 27.0 1.9 3.7e-06 27.0 1.9 2.7 2 0 0 2 2 2 1 FF domain Prp18 PF02840.15 CCC70842.1 - 0.14 12.2 2.3 4.5 7.3 0.9 2.5 2 1 0 2 2 2 0 Prp18 domain DUF2309 PF10070.9 CCC70842.1 - 0.3 9.4 1.8 0.41 8.9 1.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) DUF572 PF04502.13 CCC70842.1 - 0.56 9.8 6.0 0.88 9.1 6.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Tmemb_170 PF10190.9 CCC70843.1 - 4.4e-16 59.2 12.6 5.2e-16 58.9 12.6 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 SH3_1 PF00018.28 CCC70844.1 - 9.7e-16 57.1 0.0 1.9e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 CCC70844.1 - 5.8e-14 51.7 0.0 9.3e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 CCC70844.1 - 2.5e-08 33.5 0.0 3.7e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Pex14_N PF04695.13 CCC70844.1 - 3.1 8.4 20.8 0.6 10.7 14.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NCA2 PF08637.10 CCC70845.1 - 2.3e-97 325.7 3.9 3.8e-97 324.9 3.9 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 MFS_1 PF07690.16 CCC70846.1 - 4.2e-32 111.4 31.7 4.2e-32 111.4 31.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_transport PF06800.12 CCC70846.1 - 0.016 14.5 1.0 0.038 13.3 0.1 2.1 2 0 0 2 2 2 0 Sugar transport protein Vps62 PF06101.11 CCC70847.1 - 1.2e-08 33.8 3.1 3.1e-07 29.1 1.1 2.1 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 62 SKN1 PF03935.15 CCC70849.1 - 7.5e-255 846.0 7.1 1.1e-254 845.4 7.1 1.3 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Phosphorylase PF00343.20 CCC70850.1 - 0 1048.6 0.2 0 1048.3 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase CDP-OH_P_transf PF01066.21 CCC70851.1 - 3.6e-10 40.5 0.4 3.6e-10 40.5 0.4 1.8 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Clathrin PF00637.20 CCC70852.1 - 2.2e-188 617.7 58.8 1.8e-32 112.2 0.3 7.9 7 0 0 7 7 7 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 CCC70852.1 - 2.1e-26 91.6 1.5 5.1e-26 90.4 0.5 2.4 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.20 CCC70852.1 - 2.1e-23 81.4 4.5 8.2e-06 25.9 0.2 5.8 5 0 0 5 5 5 5 Clathrin propeller repeat Clathrin-link PF09268.10 CCC70852.1 - 1.5e-08 33.8 0.5 1.5e-08 33.8 0.5 3.0 3 0 0 3 3 3 1 Clathrin, heavy-chain linker TPR_2 PF07719.17 CCC70852.1 - 1.8 8.9 7.5 66 4.0 0.2 5.9 7 0 0 7 7 7 0 Tetratricopeptide repeat hNIFK_binding PF12196.8 CCC70853.1 - 0.029 13.8 1.1 0.072 12.6 1.1 1.6 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK hNIFK_binding PF12196.8 CCC70854.1 - 0.029 13.9 1.1 0.07 12.6 1.1 1.6 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK FACT-Spt16_Nlob PF14826.6 CCC70856.1 - 7.2e-50 168.9 6.9 7.5e-50 168.9 0.2 3.2 3 0 0 3 3 3 1 FACT complex subunit SPT16 N-terminal lobe domain SPT16 PF08644.11 CCC70856.1 - 1.7e-48 164.6 0.1 5.8e-48 162.9 0.1 2.0 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 CCC70856.1 - 1.1e-29 103.7 0.0 2.1e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 CCC70856.1 - 6.1e-13 49.0 0.3 4.2e-12 46.3 0.1 2.6 3 0 0 3 3 3 1 Histone chaperone Rttp106-like PPP4R2 PF09184.11 CCC70856.1 - 6.6 6.2 17.3 0.55 9.8 6.9 2.7 2 0 0 2 2 2 0 PPP4R2 AMPK1_CBM PF16561.5 CCC70857.1 - 9e-30 102.7 0.0 2.6e-29 101.3 0.0 1.8 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 CCC70857.1 - 2.2e-28 98.3 2.1 2.2e-28 98.3 2.1 2.9 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain SUIM_assoc PF16619.5 CCC70857.1 - 0.017 15.2 5.0 0.017 15.2 5.0 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 PRIMA1 PF16101.5 CCC70857.1 - 0.38 10.8 2.8 0.53 10.3 1.3 1.9 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Roughex PF06020.11 CCC70857.1 - 1.1 8.3 7.1 2.3 7.2 7.1 1.5 1 0 0 1 1 1 0 Drosophila roughex protein zf-C2H2 PF00096.26 CCC70858.1 - 1.9e-08 34.3 15.6 3.8e-05 23.9 2.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC70858.1 - 7.2e-07 29.4 19.5 0.00015 22.0 8.1 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC70858.1 - 1.2e-06 28.9 12.9 0.0064 17.2 4.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 CCC70858.1 - 0.0015 18.7 0.6 0.15 12.4 0.2 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCC70858.1 - 0.25 11.4 10.4 2.5 8.2 0.5 3.1 2 1 0 2 2 2 0 C2H2-type zinc finger LSM PF01423.22 CCC70859.1 - 1.2e-20 72.9 0.6 2.1e-20 72.1 0.6 1.4 1 0 0 1 1 1 1 LSM domain CHZ PF09649.10 CCC70860.1 - 8.1e-19 66.8 2.6 8.1e-19 66.8 2.6 2.9 3 0 0 3 3 3 1 Histone chaperone domain CHZ PRCC PF10253.9 CCC70860.1 - 0.29 11.9 9.6 0.33 11.7 9.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Prothymosin PF03247.14 CCC70860.1 - 3 8.3 32.5 3.6 8.1 23.2 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family DUF5364 PF17322.2 CCC70863.1 - 2.2e-52 178.1 19.8 3.4e-52 177.5 19.8 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5364) CrtC PF07143.11 CCC70863.1 - 0.14 12.8 0.3 0.17 12.6 0.3 1.2 1 0 0 1 1 1 0 CrtC N-terminal lipocalin domain PNRC PF15365.6 CCC70864.1 - 0.029 14.2 0.2 0.064 13.1 0.2 1.6 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator motif HAD_2 PF13419.6 CCC70865.1 - 7.9e-08 32.6 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCC70865.1 - 5.1e-07 30.2 0.0 6.4e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCC70865.1 - 0.044 13.8 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like HAD PF12710.7 CCC70865.1 - 0.13 12.6 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Nse5 PF08691.10 CCC70866.1 - 9.6e-25 87.2 20.3 1.5e-24 86.5 20.3 1.2 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 EamA PF00892.20 CCC70867.1 - 7.7e-10 39.1 34.7 1.4e-06 28.6 8.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family GATA PF00320.27 CCC70868.1 - 4.5e-16 58.2 3.8 8.7e-16 57.2 3.8 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 CCC70868.1 - 0.16 11.5 0.4 0.36 10.4 0.4 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding XPG_I PF00867.18 CCC70869.1 - 9.6e-20 70.7 0.0 6.6e-19 68.1 0.0 2.5 2 1 0 2 2 2 1 XPG I-region XPG_N PF00752.17 CCC70869.1 - 0.007 16.8 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain tRNA-synt_1d PF00750.19 CCC70869.1 - 0.067 12.1 0.1 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (R) DUF3449 PF11931.8 CCC70869.1 - 0.66 9.7 3.3 0.94 9.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3449) PMSR PF01625.21 CCC70870.1 - 1.2e-50 171.6 1.5 1.5e-50 171.4 1.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase AdoHcyase PF05221.17 CCC70871.1 - 3.8e-130 433.4 0.0 5.5e-74 249.0 0.2 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 CCC70871.1 - 1.2e-84 282.3 2.1 1.9e-84 281.7 2.1 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 CCC70871.1 - 1.7e-07 30.7 0.2 3.2e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 CCC70871.1 - 0.0023 17.5 0.3 0.0041 16.7 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 CCC70871.1 - 0.016 15.4 0.1 0.031 14.5 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Urocanase PF01175.18 CCC70871.1 - 0.077 12.6 0.4 0.13 11.9 0.4 1.3 1 0 0 1 1 1 0 Urocanase Rossmann-like domain YgaB PF14182.6 CCC70872.1 - 0.08 13.3 0.9 0.45 10.9 0.9 2.3 1 0 0 1 1 1 0 YgaB-like protein GlutR_dimer PF00745.20 CCC70872.1 - 0.16 12.4 4.9 11 6.5 0.0 3.4 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain SAPS PF04499.15 CCC70873.1 - 7.7e-165 549.4 11.9 7.7e-165 549.4 11.9 2.2 3 0 0 3 3 3 1 SIT4 phosphatase-associated protein DnaGprimase_HBD PF16730.5 CCC70873.1 - 0.0077 16.3 1.1 2.6 8.2 0.1 3.0 2 0 0 2 2 2 2 DnaG-primase C-terminal, helicase-binding domain RisS_PPD PF16524.5 CCC70873.1 - 0.22 11.8 1.7 0.43 10.9 0.3 2.2 3 0 0 3 3 3 0 Periplasmic domain of Sensor histidine kinase RisS DnaJ PF00226.31 CCC70874.1 - 1.2e-12 47.8 3.7 2.7e-12 46.6 2.9 2.0 2 0 0 2 2 2 1 DnaJ domain Peptidase_M20 PF01546.28 CCC70876.1 - 3.7e-30 105.2 0.0 6.4e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CCC70876.1 - 1.6e-12 47.3 0.0 3.3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 CCC70876.1 - 0.025 14.3 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 Mito_carr PF00153.27 CCC70877.1 - 2.9e-42 142.5 4.8 6.2e-18 64.5 0.1 4.3 3 2 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CCC70877.1 - 0.035 13.3 0.2 0.056 12.6 0.2 1.2 1 0 0 1 1 1 0 Fuseless IBN_N PF03810.19 CCC70879.1 - 6.8e-12 45.1 0.5 6.3e-11 42.0 0.2 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 CCC70879.1 - 0.026 14.6 21.8 0.12 12.5 0.5 6.0 5 2 0 5 5 5 0 Exportin 1-like protein 7TMR-HDED PF07697.11 CCC70879.1 - 9 6.4 7.4 57 3.7 0.9 4.3 2 2 0 2 2 2 0 7TM-HD extracellular Ank PF00023.30 CCC70880.1 - 5.2e-10 39.3 0.4 0.0032 17.8 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 CCC70880.1 - 2.8e-09 36.4 0.0 0.0033 17.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 CCC70880.1 - 2.3e-08 34.1 0.1 4e-05 23.8 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCC70880.1 - 2.1e-06 28.2 0.0 3.5e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCC70880.1 - 0.0002 21.8 0.1 0.0011 19.5 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF155 PF02582.14 CCC70881.1 - 8.4e-53 179.1 0.2 1.5e-52 178.3 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Brr6_like_C_C PF10104.9 CCC70882.1 - 1.7e-44 150.8 3.2 2.3e-44 150.4 3.2 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF2778 PF10908.8 CCC70882.1 - 0.065 13.5 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2778) S36_mt PF10937.8 CCC70883.1 - 6.7e-26 92.1 0.0 1.5e-25 91.0 0.0 1.5 1 1 0 1 1 1 1 Ribosomal protein S36, mitochondrial Proteasome PF00227.26 CCC70884.1 - 1e-23 83.9 0.0 1.3e-23 83.4 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Adap_comp_sub PF00928.21 CCC70885.1 - 7e-10 38.7 0.1 1.1e-09 38.1 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 CCC70885.1 - 4.1e-08 33.3 1.2 8.7e-08 32.2 1.2 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain SOBP PF15279.6 CCC70885.1 - 0.3 11.6 4.1 0.45 11.1 4.1 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Ppx-GppA PF02541.16 CCC70886.1 - 4.8e-67 226.4 0.0 6.7e-67 225.9 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family RRM_3 PF08777.11 CCC70886.1 - 0.013 15.5 0.0 0.034 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif CSN8_PSD8_EIF3K PF10075.9 CCC70887.1 - 8.2e-20 71.3 0.6 1.7e-19 70.2 0.4 1.6 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 CCC70887.1 - 3.1e-06 26.8 0.0 4.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP family MFS_1 PF07690.16 CCC70888.1 - 8e-29 100.7 23.5 8e-29 100.7 23.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_4 PF06779.14 CCC70888.1 - 1.2e-07 31.3 2.4 1.2e-07 31.3 2.4 2.3 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB BrkDBD PF09607.10 CCC70888.1 - 0.042 13.6 0.2 0.098 12.4 0.2 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain Sugar_tr PF00083.24 CCC70890.1 - 4.5e-168 559.8 31.0 5.4e-168 559.5 31.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC70890.1 - 1.4e-26 93.3 27.3 2.1e-26 92.7 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 CCC70890.1 - 0.029 14.7 3.7 0.42 10.9 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) DUF2530 PF10745.9 CCC70890.1 - 9 6.6 7.1 2.6 8.3 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Aldo_ket_red PF00248.21 CCC70891.1 - 9.4e-66 222.0 0.0 1.1e-65 221.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family NT5C PF06941.12 CCC70891.1 - 0.051 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) Hexokinase_2 PF03727.16 CCC70892.1 - 3.7e-78 262.2 0.0 5.4e-78 261.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 CCC70892.1 - 1.3e-70 237.3 0.0 2e-70 236.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.21 CCC70892.1 - 0.015 14.8 0.0 0.034 13.7 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain DUF2294 PF10057.9 CCC70892.1 - 0.039 14.1 0.0 0.17 12.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) DUF1691 PF07950.11 CCC70894.1 - 0.00068 20.3 0.0 0.0032 18.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1691) Integrase_Zn PF02022.19 CCC70894.1 - 0.066 13.2 0.7 0.066 13.2 0.7 1.9 2 0 0 2 2 2 0 Integrase Zinc binding domain Cytochrome_P460 PF16694.5 CCC70894.1 - 0.71 10.2 2.5 24 5.3 0.1 2.5 2 0 0 2 2 2 0 Cytochrome P460 Gp_dh_C PF02800.20 CCC70895.1 - 9.6e-70 233.2 0.1 3.5e-69 231.4 0.1 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 CCC70895.1 - 1.3e-18 67.2 0.1 3.7e-18 65.7 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PTPLA PF04387.14 CCC70896.1 - 0.064 13.0 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA GST_C PF00043.25 CCC70897.1 - 1.7e-09 37.8 0.0 3.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCC70897.1 - 0.00018 21.6 0.5 0.00035 20.7 0.5 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCC70897.1 - 0.00042 20.3 0.0 0.00098 19.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FH2 PF02181.23 CCC70899.1 - 9.2e-73 245.5 10.6 9.2e-73 245.5 10.6 2.8 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 CCC70899.1 - 2.5e-06 27.2 2.0 2.5e-06 27.2 2.0 3.3 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain SKG6 PF08693.10 CCC70900.1 - 0.00011 21.6 2.3 0.00022 20.6 2.3 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sensor PF13796.6 CCC70900.1 - 0.035 14.1 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Putative sensor Coa1 PF08695.10 CCC70901.1 - 1.5e-38 131.1 0.0 2.3e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF1748 PF08520.10 CCC70902.1 - 2.2e-29 101.1 0.1 2.5e-29 101.0 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) MOR2-PAG1_N PF14222.6 CCC70903.1 - 1.5e-185 618.4 11.6 3.1e-185 617.3 11.6 1.6 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 CCC70903.1 - 2.1e-86 289.9 1.1 2.1e-86 289.9 1.1 2.8 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.6 CCC70903.1 - 2.4e-27 95.1 11.3 2.7e-11 41.9 0.6 4.1 3 2 0 3 3 3 3 Cell morphogenesis central region Cnd1 PF12717.7 CCC70903.1 - 0.01 15.9 0.2 0.01 15.9 0.2 4.3 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 CCC70903.1 - 4.6 7.2 6.5 33 4.5 0.0 4.0 5 0 0 5 5 5 0 Importin-beta N-terminal domain UCH PF00443.29 CCC70904.1 - 6.8e-58 196.2 3.5 6.8e-58 196.2 3.5 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCC70904.1 - 8.4e-19 68.3 6.6 9.2e-18 64.9 6.6 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF4298 PF14131.6 CCC70904.1 - 0.046 13.7 0.2 0.2 11.6 0.2 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Rubredoxin_2 PF18073.1 CCC70904.1 - 5.8 6.7 7.3 12 5.8 0.3 2.4 2 0 0 2 2 2 0 Rubredoxin metal binding domain DAO PF01266.24 CCC70905.1 - 1.2e-52 179.7 0.0 1.9e-52 179.0 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 CCC70905.1 - 2.3e-38 130.9 0.0 4.1e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 CCC70905.1 - 4.6e-11 42.4 3.8 5.8e-10 38.8 3.8 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 CCC70905.1 - 1.6e-09 37.7 0.5 4.2e-07 29.7 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CCC70905.1 - 3.2e-05 23.3 0.1 0.00014 21.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCC70905.1 - 3.9e-05 22.9 1.0 0.0015 17.7 0.2 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 CCC70905.1 - 9.5e-05 21.3 0.4 0.00019 20.3 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 CCC70905.1 - 0.00045 20.4 0.4 0.0014 18.8 0.3 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CCC70905.1 - 0.0034 16.7 0.7 0.014 14.7 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 CCC70905.1 - 0.0082 15.4 0.6 0.054 12.7 0.7 2.0 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 CCC70905.1 - 0.026 15.1 1.0 0.18 12.4 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCC70905.1 - 0.027 13.7 0.2 0.061 12.6 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 CCC70905.1 - 0.046 13.6 1.3 0.17 11.8 1.3 2.0 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_pol_3_Rpc31 PF11705.8 CCC70906.1 - 0.0042 17.4 16.7 0.007 16.6 16.7 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DNA_pol_phi PF04931.13 CCC70906.1 - 0.013 13.6 21.3 0.017 13.3 21.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Pox_Ag35 PF03286.14 CCC70906.1 - 0.024 14.5 11.0 0.061 13.1 11.0 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Radial_spoke PF04712.12 CCC70906.1 - 0.11 11.4 10.2 0.16 10.9 10.2 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Nop14 PF04147.12 CCC70906.1 - 0.15 10.2 17.7 0.2 9.8 17.7 1.1 1 0 0 1 1 1 0 Nop14-like family CDC27 PF09507.10 CCC70906.1 - 0.31 10.4 20.8 0.43 9.9 20.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 RPN2_C PF18004.1 CCC70906.1 - 0.34 10.8 10.8 0.58 10.1 10.8 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain K_channel_TID PF07941.11 CCC70906.1 - 0.42 11.1 3.7 0.73 10.3 3.7 1.3 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Vfa1 PF08432.10 CCC70906.1 - 0.43 10.9 10.7 0.77 10.1 10.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Usp PF00582.26 CCC70906.1 - 0.5 10.9 6.0 8.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Universal stress protein family NOA36 PF06524.12 CCC70906.1 - 0.54 9.5 16.7 0.87 8.9 16.7 1.2 1 0 0 1 1 1 0 NOA36 protein PPP4R2 PF09184.11 CCC70906.1 - 0.56 9.7 15.5 0.86 9.1 15.5 1.4 1 0 0 1 1 1 0 PPP4R2 FGF-BP1 PF06473.12 CCC70906.1 - 0.61 9.9 3.6 1.2 9.0 3.6 1.4 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) DUF1168 PF06658.12 CCC70906.1 - 0.63 9.9 16.9 1.4 8.8 16.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) TFIIA PF03153.13 CCC70906.1 - 0.69 9.9 14.8 0.94 9.4 14.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RXT2_N PF08595.11 CCC70906.1 - 0.69 9.9 13.4 1.6 8.7 13.4 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Adeno_terminal PF02459.15 CCC70906.1 - 1 7.7 8.2 1.5 7.2 8.2 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein CSRNP_N PF16019.5 CCC70906.1 - 1.5 8.7 5.4 2.5 8.0 5.4 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus NPR3 PF03666.13 CCC70906.1 - 6.1 5.5 8.5 8.4 5.1 8.5 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CENP-B_dimeris PF09026.10 CCC70906.1 - 6.2 7.3 19.2 17 5.9 19.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Afi1 PF07792.12 CCC70906.1 - 7.4 7.1 11.9 16 6.0 11.9 1.6 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking PTPA PF03095.15 CCC70907.1 - 1.7e-105 352.8 0.0 2.1e-105 352.5 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Herpes_UL7 PF01677.16 CCC70908.1 - 0.024 14.4 0.4 0.039 13.7 0.4 1.3 1 0 0 1 1 1 0 Herpesvirus UL7 like zf-primase PF09329.11 CCC70909.1 - 1.1e-15 57.1 1.0 2.1e-15 56.2 1.0 1.5 1 0 0 1 1 1 1 Primase zinc finger DUF2767 PF10965.8 CCC70909.1 - 0.0065 16.4 0.3 0.026 14.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2767) tRNA_anti-codon PF01336.25 CCC70909.1 - 0.0085 16.1 0.0 0.053 13.5 0.0 2.2 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain TPR_MLP1_2 PF07926.12 CCC70910.1 - 1.9e-05 24.7 14.4 1.9e-05 24.7 14.4 18.0 6 5 11 17 17 17 6 TPR/MLP1/MLP2-like protein ubiquitin PF00240.23 CCC70911.1 - 3.7e-34 116.3 0.6 4.9e-34 115.9 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 CCC70911.1 - 6.1e-31 106.1 10.4 9.3e-31 105.5 10.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 CCC70911.1 - 2.2e-16 59.4 0.7 3e-16 59.0 0.7 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 CCC70911.1 - 2e-05 24.9 0.1 7.4e-05 23.1 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 CCC70911.1 - 0.0036 17.6 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 CCC70911.1 - 0.0038 17.1 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCC70911.1 - 0.0073 16.4 0.1 0.015 15.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 CCC70911.1 - 0.014 15.4 1.0 4.2 7.5 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 CCC70911.1 - 0.024 15.2 0.1 0.031 14.8 0.1 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Sde2_N_Ubi PF13019.6 CCC70911.1 - 0.083 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Silencing defective 2 N-terminal ubiquitin domain Response_reg PF00072.24 CCC70912.1 - 4.4e-28 97.7 0.6 1.3e-27 96.2 0.4 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 CCC70912.1 - 1.3e-27 96.5 0.2 9.9e-21 74.3 0.0 2.7 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 CCC70912.1 - 2.8e-11 43.3 0.2 7.4e-11 41.9 0.2 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.25 CCC70912.1 - 0.00064 20.0 0.1 0.23 11.8 0.0 2.5 2 0 0 2 2 2 2 HAMP domain HCO3_cotransp PF00955.21 CCC70913.1 - 0.033 13.0 1.8 0.061 12.2 1.8 1.3 1 0 0 1 1 1 0 HCO3- transporter family Nop53 PF07767.11 CCC70913.1 - 0.14 11.5 7.2 0.31 10.4 7.2 1.5 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FAM76 PF16046.5 CCC70913.1 - 0.76 9.1 11.2 0.033 13.5 5.2 1.7 2 0 0 2 2 2 0 FAM76 protein tRNA_bind_2 PF13725.6 CCC70913.1 - 1.4 8.6 8.8 1.7 8.3 0.0 2.5 2 0 0 2 2 2 0 Possible tRNA binding domain Pheromone PF08015.11 CCC70913.1 - 6.9 7.8 8.9 57 4.9 1.6 4.0 4 0 0 4 4 4 0 Fungal mating-type pheromone Pantoate_ligase PF02569.15 CCC70914.1 - 5.6e-94 314.3 0.0 6.4e-94 314.1 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Ndc80_HEC PF03801.13 CCC70915.1 - 7.4e-48 162.0 2.4 7.4e-48 162.0 2.4 3.0 1 1 2 3 3 3 1 HEC/Ndc80p family DUF5595 PF18077.1 CCC70915.1 - 4.2e-13 49.2 4.3 4.2e-13 49.2 4.3 4.7 5 2 1 6 6 6 1 Domain of unknown function (DUF5595) Spc7 PF08317.11 CCC70915.1 - 0.0012 17.7 45.9 0.015 14.2 19.0 3.2 3 1 0 3 3 3 2 Spc7 kinetochore protein Atg14 PF10186.9 CCC70915.1 - 0.0035 16.5 14.5 0.0035 16.5 14.5 2.7 2 1 0 2 2 2 1 Vacuolar sorting 38 and autophagy-related subunit 14 TPR_MLP1_2 PF07926.12 CCC70915.1 - 0.014 15.5 32.3 0.08 13.0 17.0 3.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 CCC70915.1 - 0.21 11.7 37.1 0.038 14.0 3.7 4.5 2 2 0 4 4 4 0 Designed helical repeat protein 10 domain Golgin_A5 PF09787.9 CCC70915.1 - 1 8.8 41.9 2.2 7.6 19.4 3.2 2 1 1 3 3 3 0 Golgin subfamily A member 5 ATG16 PF08614.11 CCC70915.1 - 5.2 7.2 35.2 0.44 10.7 6.1 4.0 2 2 1 3 3 3 0 Autophagy protein 16 (ATG16) Cytochrom_B562 PF07361.11 CCC70915.1 - 6.5 7.5 24.2 0.03 15.0 3.6 4.5 2 1 3 5 5 5 0 Cytochrome b562 Bap31_Bap29_C PF18035.1 CCC70915.1 - 8.6 6.4 19.1 0.65 10.0 1.8 4.3 3 1 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain ERCC3_RAD25_C PF16203.5 CCC70916.1 - 2.8e-125 416.5 0.5 5e-125 415.7 0.5 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 CCC70916.1 - 5.9e-36 123.4 0.0 1.4e-35 122.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC70916.1 - 2.6e-16 60.1 0.0 5.1e-16 59.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCC70916.1 - 6.3e-12 45.8 0.1 1.4e-11 44.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 CCC70916.1 - 7.2e-09 34.8 0.0 8.5e-09 34.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 CCC70916.1 - 2.6e-05 24.0 0.0 5.9e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.6 CCC70916.1 - 0.033 13.6 0.0 0.088 12.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial extracellular solute-binding protein Abhydrolase_6 PF12697.7 CCC70917.1 - 9.4e-14 52.5 0.0 1.4e-13 52.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 CCC70917.1 - 1.2e-05 25.1 0.1 6.6e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCC70917.1 - 0.00014 21.2 0.0 0.00029 20.2 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 CCC70917.1 - 0.0018 17.9 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 CCC70917.1 - 0.024 14.3 0.2 0.048 13.4 0.1 1.6 1 1 0 1 1 1 0 PGAP1-like protein Whi5 PF08528.11 CCC70918.1 - 1.7e-11 43.5 0.4 2.9e-11 42.7 0.4 1.4 1 0 0 1 1 1 1 Whi5 like LIM PF00412.22 CCC70920.1 - 8.1e-09 35.6 17.7 8.9e-09 35.5 8.8 2.4 2 0 0 2 2 2 2 LIM domain DUF664 PF04978.12 CCC70920.1 - 0.023 15.1 0.1 0.048 14.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF664) Chlam_OMP PF01308.17 CCC70920.1 - 0.27 10.0 0.5 1.2 7.8 0.0 1.9 2 0 0 2 2 2 0 Chlamydia major outer membrane protein Cytochrome_C7 PF14522.6 CCC70920.1 - 0.4 10.7 9.3 1.3 9.1 5.3 2.8 2 0 0 2 2 2 0 Cytochrome c7 and related cytochrome c DUF3336 PF11815.8 CCC70921.1 - 7.5e-33 113.2 7.5 1.1e-32 112.6 6.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.22 CCC70921.1 - 2e-26 93.4 0.0 4.2e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_1 PF00515.28 CCC70922.1 - 8.4e-11 41.2 6.0 0.00024 20.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCC70922.1 - 7.2e-10 38.2 6.3 0.0016 18.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 CCC70922.1 - 4.9e-08 33.2 1.3 0.0028 17.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCC70922.1 - 1.8e-07 30.7 3.0 0.014 15.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat F-box-like PF12937.7 CCC70922.1 - 0.00013 21.8 0.1 0.00031 20.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like TPR_11 PF13414.6 CCC70922.1 - 0.00015 21.4 2.8 0.0078 15.9 0.0 2.7 2 1 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 CCC70922.1 - 0.00015 21.7 11.0 0.0012 18.8 0.1 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat F-box PF00646.33 CCC70922.1 - 0.001 18.9 0.2 0.0062 16.4 0.1 2.4 2 0 0 2 2 2 1 F-box domain TPR_14 PF13428.6 CCC70922.1 - 0.0011 19.5 0.1 4.8 8.3 0.1 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat LRR_6 PF13516.6 CCC70922.1 - 0.0019 18.1 0.5 6.8 7.0 0.0 4.0 3 0 0 3 3 3 1 Leucine Rich repeat TPR_10 PF13374.6 CCC70922.1 - 0.0025 17.6 0.1 0.13 12.1 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 CCC70922.1 - 0.025 14.6 1.0 5.6 7.1 0.1 2.8 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_21 PF09976.9 CCC70922.1 - 0.031 14.0 0.1 1 9.0 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain TPR_17 PF13431.6 CCC70922.1 - 0.036 14.5 2.3 6.6 7.4 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCC70922.1 - 0.045 14.4 4.7 3.7 8.4 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC70922.1 - 0.062 13.5 6.0 0.25 11.6 0.3 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 CCC70922.1 - 0.067 13.2 0.1 0.21 11.6 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_9 PF13371.6 CCC70922.1 - 0.098 12.8 0.0 0.96 9.6 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.7 CCC70922.1 - 0.11 12.6 0.1 4.2 7.5 0.1 2.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) BTAD PF03704.17 CCC70922.1 - 0.17 12.4 0.2 0.41 11.1 0.2 1.6 1 0 0 1 1 1 0 Bacterial transcriptional activator domain LRR_4 PF12799.7 CCC70922.1 - 0.3 11.6 24.5 3.9 8.0 0.3 6.4 4 2 3 7 7 6 0 Leucine Rich repeats (2 copies) Zip PF02535.22 CCC70923.1 - 1.4e-42 146.1 9.3 6.7e-26 91.3 1.5 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter U3_snoRNA_assoc PF08297.11 CCC70924.1 - 2.4e-19 69.8 2.5 2.4e-19 69.8 2.5 3.8 2 1 2 4 4 4 1 U3 snoRNA associated eIF3_subunit PF08597.10 CCC70924.1 - 1.1 9.1 31.2 1.8 8.4 31.2 1.3 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit CDC45 PF02724.14 CCC70924.1 - 1.3 7.3 19.0 1.4 7.1 19.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Ureide_permease PF07168.11 CCC70924.1 - 1.7 7.3 6.7 2.3 6.9 6.7 1.3 1 0 0 1 1 1 0 Ureide permease SOBP PF15279.6 CCC70924.1 - 3.7 8.1 8.7 4.7 7.7 8.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein ALMT PF11744.8 CCC70924.1 - 6.8 5.4 9.2 7.7 5.2 9.2 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Kin17_mid PF10357.9 CCC70925.1 - 5.2e-43 146.0 7.7 1.1e-42 144.9 7.7 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.8 CCC70925.1 - 0.00011 22.3 4.4 0.0003 21.0 4.4 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 CCC70925.1 - 0.00016 21.9 2.5 0.00042 20.6 2.5 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF5382 PF17354.2 CCC70925.1 - 0.0011 17.9 1.3 0.0015 17.5 1.3 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5382) C1q PF00386.21 CCC70925.1 - 0.0023 18.1 0.3 0.005 17.1 0.3 1.5 1 0 0 1 1 1 1 C1q domain zf-C2H2_2 PF12756.7 CCC70925.1 - 0.014 15.7 0.7 0.014 15.7 0.7 2.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 CCC70925.1 - 0.079 13.8 1.7 0.22 12.5 1.7 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger TFIID_NTD2 PF04494.15 CCC70925.1 - 0.85 9.9 6.3 0.5 10.6 2.9 2.3 2 1 0 2 2 2 0 WD40 associated region in TFIID subunit, NTD2 domain GTP_EFTU PF00009.27 CCC70926.1 - 8.1e-19 67.9 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CCC70926.1 - 0.00023 21.2 0.5 0.00086 19.4 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.17 CCC70926.1 - 0.00066 20.0 0.0 0.0019 18.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Arf PF00025.21 CCC70926.1 - 0.018 14.5 0.1 1.9 7.9 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 CCC70926.1 - 0.029 14.6 0.4 0.47 10.7 0.4 2.5 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Hormone_3 PF00159.18 CCC70926.1 - 0.15 12.1 0.3 0.35 11.0 0.3 1.6 1 0 0 1 1 1 0 Pancreatic hormone peptide DUF5381 PF17353.2 CCC70926.1 - 0.23 11.2 2.2 1.2 8.9 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5381) Thymidylat_synt PF00303.19 CCC70927.1 - 4.8e-113 376.7 0.0 5.5e-113 376.6 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase Shugoshin_N PF07558.11 CCC70928.1 - 2.5e-15 56.1 9.5 2.1e-14 53.1 7.7 2.8 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.11 CCC70928.1 - 8.1e-10 38.3 4.4 3.6e-09 36.3 4.4 2.2 1 0 0 1 1 1 1 Shugoshin C terminus CHZ PF09649.10 CCC70928.1 - 0.0083 15.6 0.1 0.027 13.9 0.1 1.9 1 0 0 1 1 1 1 Histone chaperone domain CHZ TSC22 PF01166.18 CCC70928.1 - 0.077 13.3 4.4 0.11 12.8 2.2 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF3461 PF11944.8 CCC70928.1 - 4.2 7.5 11.9 0.22 11.6 4.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) Brix PF04427.18 CCC70929.1 - 1.6e-40 139.3 0.5 2.3e-40 138.8 0.5 1.2 1 0 0 1 1 1 1 Brix domain DUF1086 PF06461.11 CCC70929.1 - 0.025 14.5 0.5 0.053 13.4 0.2 1.7 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1086) RabGAP-TBC PF00566.18 CCC70930.1 - 3.9e-49 167.2 6.0 4.1e-49 167.2 4.3 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Vps5 PF09325.10 CCC70931.1 - 2e-61 207.6 8.0 3.6e-61 206.7 8.0 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CCC70931.1 - 1e-20 73.8 0.4 2.4e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 PX domain CEP209_CC5 PF16574.5 CCC70931.1 - 0.035 14.3 0.3 0.035 14.3 0.3 2.3 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 CENP-F_leu_zip PF10473.9 CCC70931.1 - 0.046 13.7 7.3 0.041 13.9 3.6 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2408 PF10303.9 CCC70931.1 - 0.057 14.0 3.1 0.086 13.4 1.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) Baculo_PEP_C PF04513.12 CCC70931.1 - 0.17 11.9 6.2 0.45 10.5 2.1 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PLC-beta_C PF08703.10 CCC70931.1 - 0.22 11.5 5.0 0.27 11.2 1.6 2.5 2 0 0 2 2 2 0 PLC-beta C terminal Alg6_Alg8 PF03155.15 CCC70932.1 - 3.7e-166 553.8 37.6 4.4e-166 553.6 37.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Cytochrom_C1 PF02167.15 CCC70934.1 - 2e-96 322.0 0.0 2.4e-96 321.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 CCC70934.1 - 0.0018 18.6 0.0 0.0037 17.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 CCC70934.1 - 0.005 18.0 0.3 0.02 16.0 0.2 2.0 2 1 0 2 2 2 1 Cytochrome c SelP_N PF04592.14 CCC70935.1 - 0.2 11.0 18.7 0.31 10.4 18.7 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NicO PF03824.16 CCC70935.1 - 4.6 6.5 6.9 6.1 6.1 6.9 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Pkinase PF00069.25 CCC70936.1 - 2.2e-57 194.4 0.0 2.6e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC70936.1 - 2.8e-15 56.3 0.0 3.9e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 CCC70936.1 - 3.6e-07 30.3 0.1 8.8e-07 29.1 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 CCC70936.1 - 0.035 13.7 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 CCC70936.1 - 0.066 12.5 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 CCC70936.1 - 0.099 11.4 0.1 0.2 10.4 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase Sld7_N PF18636.1 CCC70937.1 - 4.1e-42 143.4 0.1 6e-42 142.9 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial morphogenesis protein SLD7 N-terminal domain Sld7_C PF18596.1 CCC70937.1 - 1e-20 73.6 0.0 2.2e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Sld7 C-terminal domain DUF676 PF05057.14 CCC70938.1 - 1e-47 162.5 0.1 1.4e-47 162.0 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 CCC70938.1 - 2.3e-07 30.8 0.0 4.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Palm_thioest PF02089.15 CCC70938.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.6 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 CCC70938.1 - 0.053 12.8 0.2 0.19 11.1 0.0 2.0 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) DUF2340 PF10209.9 CCC70939.1 - 4e-52 175.7 1.8 4.7e-52 175.5 1.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) MAP65_ASE1 PF03999.12 CCC70940.1 - 2e-116 390.1 57.9 2e-116 390.1 57.9 2.0 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) SRP1_TIP1 PF00660.17 CCC70941.1 - 0.00012 22.1 2.9 0.00012 22.1 2.9 2.0 2 0 0 2 2 2 1 Seripauperin and TIP1 family Flavoprotein PF02441.19 CCC70942.1 - 3e-51 173.3 0.1 5e-51 172.6 0.1 1.4 1 0 0 1 1 1 1 Flavoprotein Nop14 PF04147.12 CCC70942.1 - 0.006 14.9 38.1 0.0085 14.4 38.1 1.1 1 0 0 1 1 1 1 Nop14-like family BUD22 PF09073.10 CCC70942.1 - 0.042 13.2 32.6 0.085 12.2 32.6 1.4 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 CCC70942.1 - 0.5 9.1 14.0 0.88 8.3 14.0 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Mpp10 PF04006.12 CCC70942.1 - 0.56 8.6 32.8 0.88 7.9 32.8 1.2 1 0 0 1 1 1 0 Mpp10 protein CNDH2_C PF16858.5 CCC70942.1 - 0.81 9.5 15.0 1.4 8.7 15.0 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Zip PF02535.22 CCC70942.1 - 0.87 8.7 7.7 0.62 9.2 3.9 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter CPSF100_C PF13299.6 CCC70942.1 - 3.7 7.7 5.5 15 5.7 5.5 2.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SDA1 PF05285.12 CCC70942.1 - 4.3 6.7 45.7 8.2 5.7 45.7 1.4 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CCC70942.1 - 5.3 5.2 32.2 9.6 4.4 32.2 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 CCC70942.1 - 7.2 4.6 54.5 14 3.6 54.5 1.4 1 0 0 1 1 1 0 DNA polymerase phi Trypan_PARP PF05887.11 CCC70942.1 - 7.3 6.6 16.7 20 5.2 16.7 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Presenilin PF01080.17 CCC70942.1 - 7.9 5.1 8.9 49 2.5 0.0 2.2 2 0 0 2 2 2 0 Presenilin zf-AN1 PF01428.16 CCC70943.1 - 8.2e-12 45.1 5.6 9.2e-12 44.9 5.0 1.4 1 1 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.15 CCC70943.1 - 0.018 15.4 5.2 0.031 14.6 5.2 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain C5HCH PF17982.1 CCC70943.1 - 0.33 11.1 8.1 0.7 10.1 8.1 1.6 1 0 0 1 1 1 0 NSD Cys-His rich domain Nro1 PF12753.7 CCC70944.1 - 3e-144 481.0 23.7 3.4e-144 480.8 23.7 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 FAST_1 PF06743.15 CCC70944.1 - 2.5e-05 24.1 0.5 0.00016 21.5 0.3 2.3 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 1 RTA1 PF04479.13 CCC70945.1 - 2.4e-74 249.4 7.8 3.4e-74 248.9 7.8 1.2 1 0 0 1 1 1 1 RTA1 like protein XRN_M PF17846.1 CCC70946.1 - 2.2e-134 448.7 1.9 8.3e-99 331.5 0.6 2.4 1 1 1 2 2 2 2 Xrn1 helical domain XRN_N PF03159.18 CCC70946.1 - 6.7e-99 330.2 0.1 3.7e-98 327.8 0.0 2.1 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus STD1 PF17235.2 CCC70947.1 - 5e-75 251.6 0.5 5e-75 251.6 0.5 2.1 3 1 0 3 3 3 1 STD1/MTH1 DEAD PF00270.29 CCC70948.1 - 2.1e-35 122.0 0.1 3.7e-35 121.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC70948.1 - 9.4e-28 96.8 0.0 2.1e-27 95.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.6 CCC70948.1 - 0.003 17.3 0.1 0.041 13.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 CCC70948.1 - 0.12 11.7 8.9 3.2 7.0 6.5 2.8 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 CCC70948.1 - 0.15 12.4 0.6 1.8 8.8 0.2 2.6 2 1 0 2 2 2 0 AAA domain Pmp3 PF01679.17 CCC70949.1 - 1.2e-16 60.6 8.5 1.3e-16 60.5 8.5 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator FOLN PF09289.10 CCC70949.1 - 0.024 14.8 0.1 0.032 14.4 0.1 1.2 1 0 0 1 1 1 0 Follistatin/Osteonectin-like EGF domain Tom6 PF17112.5 CCC70950.1 - 3.3e-29 100.1 1.0 4.2e-29 99.8 1.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom6, fungal ATF7IP_BD PF16788.5 CCC70952.1 - 0.13 12.4 10.3 0.021 15.0 5.8 2.1 2 0 0 2 2 2 0 ATF-interacting protein binding domain RRP14 PF15459.6 CCC70952.1 - 0.13 12.9 0.8 0.87 10.2 0.2 2.6 2 0 0 2 2 2 0 60S ribosome biogenesis protein Rrp14 CUE PF02845.16 CCC70953.1 - 5.2e-11 42.0 0.1 1.8e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 CUE domain HAGH_C PF16123.5 CCC70954.1 - 6.6e-20 71.4 0.3 1.1e-19 70.7 0.3 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 CCC70954.1 - 1.3e-08 35.1 1.1 5.1e-07 29.9 1.1 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 CCC70954.1 - 0.0074 15.8 1.1 0.015 14.8 1.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CK_II_beta PF01214.18 CCC70955.1 - 1.7e-71 239.8 0.2 2e-71 239.5 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit AAA-ATPase_like PF09820.9 CCC70955.1 - 0.0026 17.2 0.2 0.0038 16.7 0.2 1.2 1 0 0 1 1 1 1 Predicted AAA-ATPase Hira PF07569.11 CCC70956.1 - 9.8e-85 283.8 4.4 1.3e-82 276.8 0.1 3.8 4 0 0 4 4 4 2 TUP1-like enhancer of split WD40 PF00400.32 CCC70956.1 - 0.48 11.4 5.9 4 8.5 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat FAD_binding_6 PF00970.24 CCC70957.1 - 5.1e-06 26.8 0.0 4.4e-05 23.7 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Syntaxin_2 PF14523.6 CCC70958.1 - 7.6e-19 68.0 10.2 7.6e-19 68.0 10.2 3.0 2 1 1 3 3 3 2 Syntaxin-like protein SNARE PF05739.19 CCC70958.1 - 8.2e-12 44.9 1.2 8.2e-12 44.9 1.2 2.3 2 1 0 2 2 2 1 SNARE domain CdvA PF18822.1 CCC70958.1 - 9.9e-05 22.2 0.3 9.9e-05 22.2 0.3 3.1 1 1 1 3 3 3 1 CdvA-like coiled-coil domain Syntaxin PF00804.25 CCC70958.1 - 0.00013 21.7 20.0 0.0019 17.9 20.0 2.5 1 1 0 1 1 1 1 Syntaxin T3SS_basalb_I PF17001.5 CCC70958.1 - 0.1 13.2 0.2 0.1 13.2 0.2 3.4 2 1 2 4 4 4 0 Type III secretion basal body protein I, YscI, HrpB, PscI Vfa1 PF08432.10 CCC70958.1 - 1.2 9.4 10.7 2.3 8.5 10.7 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 T6PP_N PF18572.1 CCC70958.1 - 1.8 8.4 11.6 0.1 12.4 4.9 2.2 2 0 0 2 2 2 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain DUF1664 PF07889.12 CCC70958.1 - 3.3 7.8 21.2 3.6 7.7 0.5 4.0 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 CCC70958.1 - 8.4 5.2 18.9 5.1e+02 -0.7 18.9 2.0 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF2703 PF10865.8 CCC70958.1 - 8.6 6.6 7.9 10 6.3 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF2703) DUF2203 PF09969.9 CCC70958.1 - 8.7 7.1 14.6 43 4.9 5.6 3.3 1 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Adaptin_binding PF10199.9 CCC70959.1 - 0.23 12.0 0.9 21 5.8 0.0 2.5 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 zf-C3HC4_3 PF13920.6 CCC70961.1 - 9.3e-08 31.8 6.8 9.3e-08 31.8 6.8 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCC70961.1 - 0.0026 17.5 8.0 0.0026 17.5 8.0 3.7 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 CCC70961.1 - 0.024 15.1 2.2 0.024 15.1 2.2 7.0 7 0 0 7 7 7 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 CCC70961.1 - 0.038 14.0 0.6 0.038 14.0 0.6 5.2 4 1 1 5 5 5 0 C2H2-type zinc finger zf-met PF12874.7 CCC70961.1 - 0.055 13.9 0.3 0.055 13.9 0.3 4.4 5 0 0 5 5 5 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 CCC70961.1 - 0.059 14.2 1.3 0.059 14.2 1.3 8.3 8 1 0 8 8 8 0 C2H2-type zinc finger UNC45-central PF11701.8 CCC70962.1 - 1.9e-27 96.1 0.5 1.9e-27 96.1 0.5 2.9 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central Ank_2 PF12796.7 CCC70963.1 - 2.9e-25 88.7 3.3 1.8e-11 44.4 0.3 3.0 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCC70963.1 - 6.1e-19 68.1 4.0 1.3e-06 28.9 0.1 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCC70963.1 - 1.2e-16 59.1 9.2 0.00068 19.9 0.0 7.3 8 0 0 8 8 8 4 Ankyrin repeat Ank PF00023.30 CCC70963.1 - 1.1e-15 57.2 1.7 2.8e-06 27.5 0.2 5.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 CCC70963.1 - 3e-15 56.1 1.0 7.7e-06 26.1 0.0 3.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) TMIE PF16038.5 CCC70963.1 - 0.039 13.8 0.1 14 5.6 0.1 2.6 2 0 0 2 2 2 0 TMIE protein XPG_N PF00752.17 CCC70964.1 - 5.9e-32 110.2 0.2 8.6e-30 103.2 0.0 3.0 3 0 0 3 3 3 1 XPG N-terminal domain XPG_I PF00867.18 CCC70964.1 - 3.6e-21 75.3 0.7 1e-20 73.9 0.0 2.2 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 CCC70964.1 - 0.015 14.8 1.1 0.053 13.0 0.0 2.0 2 0 0 2 2 2 0 XPG domain containing TPR_8 PF13181.6 CCC70964.1 - 0.025 14.8 0.0 0.12 12.6 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat 5_3_exonuc PF01367.20 CCC70964.1 - 0.071 13.7 0.0 0.38 11.4 0.0 2.2 2 0 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold HLH PF00010.26 CCC70965.1 - 6.2e-18 64.5 0.0 1.9e-17 63.0 0.0 1.9 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain PalH PF08733.10 CCC70966.1 - 2.6e-101 338.9 21.7 4.4e-101 338.2 21.7 1.3 1 0 0 1 1 1 1 PalH/RIM21 bZIP_1 PF00170.21 CCC70967.1 - 5.2e-10 39.3 13.1 5.2e-10 39.3 13.1 1.6 2 0 0 2 2 2 1 bZIP transcription factor TMCO5 PF14992.6 CCC70967.1 - 0.036 13.6 3.6 0.072 12.7 3.6 1.5 1 0 0 1 1 1 0 TMCO5 family HALZ PF02183.18 CCC70967.1 - 0.037 14.2 0.6 0.076 13.2 0.6 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper bZIP_Maf PF03131.17 CCC70967.1 - 0.099 13.2 11.6 0.079 13.5 9.9 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor Tis11B_N PF04553.12 CCC70967.1 - 0.11 13.1 0.3 0.11 13.1 0.3 2.4 3 0 0 3 3 3 0 Tis11B like protein, N terminus TPR_1 PF00515.28 CCC70968.1 - 3e-44 147.1 29.4 6.4e-08 32.1 0.2 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat STI1 PF17830.1 CCC70968.1 - 2.4e-38 129.8 14.8 3.5e-19 68.5 4.5 2.9 3 0 0 3 3 2 2 STI1 domain TPR_2 PF07719.17 CCC70968.1 - 2.7e-37 123.9 26.5 7.3e-06 25.7 0.1 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 CCC70968.1 - 4.2e-22 77.5 22.3 0.0028 17.3 0.1 8.6 7 1 1 8 8 8 7 TPR repeat TPR_12 PF13424.6 CCC70968.1 - 1.9e-21 76.1 14.7 1.5e-07 31.6 0.8 6.1 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 CCC70968.1 - 7.1e-21 72.6 25.2 0.00013 21.9 0.1 9.2 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 CCC70968.1 - 4.4e-17 62.4 10.3 0.00017 22.2 0.0 7.0 3 3 4 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 CCC70968.1 - 2.2e-16 59.1 9.2 0.29 12.1 0.1 9.0 3 3 6 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 CCC70968.1 - 5e-15 55.8 17.4 8.3e-05 23.0 0.1 7.2 4 3 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.6 CCC70968.1 - 1.5e-13 50.1 11.5 0.0026 18.0 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 CCC70968.1 - 2e-13 49.3 10.9 0.00074 19.4 0.0 7.5 8 1 1 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 CCC70968.1 - 3.4e-10 39.5 16.3 0.04 13.8 0.1 7.7 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.6 CCC70968.1 - 1.4e-08 34.8 0.3 0.00017 21.6 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 CCC70968.1 - 0.00065 19.1 13.3 5.8 6.5 0.0 6.8 7 0 0 7 7 7 1 SHNi-TPR DUF3808 PF10300.9 CCC70968.1 - 0.00079 18.3 0.1 0.00079 18.3 0.1 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF3808) TPR_6 PF13174.6 CCC70968.1 - 0.00097 19.6 26.4 0.42 11.4 0.2 8.7 10 0 0 10 10 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC70968.1 - 0.0096 16.1 15.5 0.69 10.2 0.4 5.2 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 NARP1 PF12569.8 CCC70968.1 - 0.011 14.7 1.4 0.011 14.7 1.4 4.6 2 1 3 5 5 4 0 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 CCC70968.1 - 0.011 16.0 0.6 0.011 16.0 0.6 4.7 5 1 0 5 5 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCC70968.1 - 0.026 14.6 5.0 28 4.9 0.0 4.8 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.7 CCC70968.1 - 0.026 14.6 8.7 6.1 6.9 0.7 4.6 3 2 0 3 3 3 0 Domain of Unknown Function (DUF3856) PPR PF01535.20 CCC70968.1 - 1.8 9.0 4.9 9.3 6.7 0.0 4.5 6 0 0 6 6 5 0 PPR repeat XPC-binding PF09280.11 CCC70968.1 - 2.4 7.9 5.8 2.4 8.0 1.3 2.8 2 1 0 2 2 2 0 XPC-binding domain TPR_3 PF07720.12 CCC70968.1 - 2.7 8.1 7.9 25 5.0 0.2 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF2975 PF11188.8 CCC70969.1 - 0.069 13.0 3.2 1 9.2 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) BPD_transp_1 PF00528.22 CCC70969.1 - 1.4 8.6 8.1 2.2 8.0 7.7 1.6 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component SIR2 PF02146.17 CCC70971.1 - 7.7e-37 126.9 0.0 4.5e-34 117.9 0.0 2.5 1 1 0 1 1 1 1 Sir2 family Zn-ribbon_8 PF09723.10 CCC70971.1 - 0.015 15.4 0.2 0.04 14.1 0.2 1.7 1 0 0 1 1 1 0 Zinc ribbon domain zf-RING_7 PF02591.15 CCC70971.1 - 0.065 13.4 0.4 0.19 11.9 0.4 1.9 1 0 0 1 1 1 0 C4-type zinc ribbon domain Cpn10 PF00166.21 CCC70973.1 - 7.1e-28 96.5 0.3 7.9e-28 96.4 0.3 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit ATP19 PF11022.8 CCC70974.1 - 5e-13 49.2 0.0 5.6e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit K Acetyltransf_1 PF00583.25 CCC70977.1 - 1.7e-13 50.8 0.0 2.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 CCC70977.1 - 5.8e-08 32.7 0.0 8.4e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 CCC70977.1 - 1.5e-05 25.3 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 CCC70977.1 - 5e-05 23.2 0.0 8.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 CCC70977.1 - 0.0008 18.9 1.1 0.0015 18.0 1.0 1.6 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_9 PF13527.7 CCC70977.1 - 0.0014 18.7 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 CCC70977.1 - 0.061 13.5 0.0 0.15 12.2 0.0 1.8 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Metallophos_2 PF12850.7 CCC70978.1 - 2.6e-05 24.5 0.0 4.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GAGA_bind PF06217.12 CCC70978.1 - 0.016 15.5 0.6 0.018 15.3 0.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family SAPS PF04499.15 CCC70978.1 - 0.018 13.9 4.4 0.019 13.8 4.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 CCC70978.1 - 0.37 9.0 10.3 0.44 8.8 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein MCM_bind PF09739.9 CCC70978.1 - 0.45 8.9 9.4 0.6 8.5 9.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor CSRNP_N PF16019.5 CCC70978.1 - 0.58 10.0 4.3 0.92 9.4 4.3 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus V_ATPase_I PF01496.19 CCC70978.1 - 0.79 7.6 4.1 0.95 7.3 4.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Membralin PF09746.9 CCC70978.1 - 0.95 8.4 3.8 1.3 8.0 3.8 1.1 1 0 0 1 1 1 0 Tumour-associated protein Nop14 PF04147.12 CCC70978.1 - 2.2 6.4 17.3 2.7 6.1 17.3 1.0 1 0 0 1 1 1 0 Nop14-like family Menin PF05053.13 CCC70978.1 - 2.4 6.4 8.3 3 6.1 8.3 1.1 1 0 0 1 1 1 0 Menin LAP1C PF05609.12 CCC70978.1 - 8.2 5.4 15.1 11 4.9 15.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3807 PF12720.7 CCC70978.1 - 9.3 6.5 17.6 79 3.5 16.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) tRNA-synt_2b PF00587.25 CCC70979.1 - 9.6e-23 81.1 0.0 2.2e-22 79.9 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 CCC70979.1 - 2.8e-05 24.3 3.5 5.5e-05 23.3 3.5 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 CCC70979.1 - 0.0027 17.0 1.0 0.0042 16.4 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) DUF2031 PF09592.10 CCC70979.1 - 0.011 15.3 1.0 0.019 14.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Med15_fungi PF05397.12 CCC70979.1 - 0.059 13.6 4.4 0.12 12.6 3.9 1.7 1 1 1 2 2 2 0 Mediator complex subunit 15 FmiP_Thoc5 PF09766.9 CCC70979.1 - 0.12 11.7 4.2 0.17 11.1 4.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 DUF1664 PF07889.12 CCC70979.1 - 0.21 11.7 2.0 0.66 10.0 2.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Occludin_ELL PF07303.13 CCC70979.1 - 0.64 10.8 3.7 1.3 9.8 3.7 1.4 1 0 0 1 1 1 0 Occludin homology domain DUF724 PF05266.14 CCC70979.1 - 3.3 7.5 8.6 8.9 6.1 8.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Ribosomal_L27e PF01777.18 CCC70980.1 - 1e-36 125.1 7.8 1.5e-36 124.6 7.8 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 CCC70980.1 - 0.00063 19.6 1.6 0.0012 18.7 1.6 1.5 1 0 0 1 1 1 1 KOW motif DAO PF01266.24 CCC70981.1 - 3.1e-72 244.1 0.0 4.3e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 CCC70981.1 - 1.4e-05 25.3 0.0 4.4e-05 23.6 0.0 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CCC70981.1 - 0.00037 19.8 0.0 0.0007 18.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 CCC70981.1 - 0.00043 19.6 0.0 0.0058 15.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 CCC70981.1 - 0.0014 18.9 0.3 0.0032 17.7 0.1 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain MCRA PF06100.11 CCC70981.1 - 0.0098 14.7 0.0 0.023 13.5 0.0 1.7 1 0 0 1 1 1 1 MCRA family Trp_halogenase PF04820.14 CCC70981.1 - 0.012 14.5 0.3 0.32 9.8 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.6 CCC70981.1 - 0.025 14.6 0.0 0.056 13.4 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 CCC70981.1 - 0.039 14.5 0.1 0.094 13.3 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF755 PF05501.11 CCC70981.1 - 0.47 10.7 10.3 0.91 9.8 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Sod_Fe_C PF02777.18 CCC70982.1 - 5.8e-33 113.1 0.7 5.8e-33 113.1 0.7 1.5 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 CCC70982.1 - 6.8e-26 90.6 0.4 1.4e-25 89.6 0.4 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.7 CCC70982.1 - 0.095 12.8 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif p450 PF00067.22 CCC70983.1 - 2.9e-101 339.5 0.1 3.3e-101 339.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3666 PF12408.8 CCC70983.1 - 0.3 10.3 4.2 4.4 6.6 0.1 3.1 3 0 0 3 3 3 0 Ribose-5-phosphate isomerase Flo11 PF10182.9 CCC70984.1 - 2.7e-66 222.3 1.7 3.5e-66 222.0 1.7 1.1 1 0 0 1 1 1 1 Flo11 domain LCAT PF02450.15 CCC70985.1 - 7.1e-133 443.6 0.5 1e-132 443.0 0.5 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF1749 PF08538.10 CCC70985.1 - 0.0013 17.8 0.0 0.0026 16.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Lipase_2 PF01674.18 CCC70985.1 - 0.0019 17.7 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 CCC70985.1 - 0.016 14.9 0.0 0.058 13.0 0.0 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 CCC70985.1 - 0.04 13.2 0.0 0.14 11.4 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF900 PF05990.12 CCC70985.1 - 0.074 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) LIDHydrolase PF10230.9 CCC70985.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_6 PF12697.7 CCC70985.1 - 0.12 13.0 0.0 0.23 12.0 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Autophagy_N PF03986.13 CCC70986.1 - 1.6e-42 144.7 2.4 2.2e-42 144.2 0.1 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 CCC70986.1 - 1.1e-15 57.9 0.1 2.8e-15 56.6 0.1 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 CCC70986.1 - 1.3e-15 56.5 2.0 2.8e-15 55.5 2.0 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal VHS PF00790.19 CCC70987.1 - 1.4e-37 128.7 0.2 1.4e-37 128.7 0.2 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.21 CCC70987.1 - 1.8e-19 69.7 4.5 4e-19 68.5 4.5 1.6 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.20 CCC70987.1 - 2.7e-08 33.2 8.7 0.00022 20.9 2.0 3.2 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF892 PF05974.12 CCC70987.1 - 0.0014 18.7 1.1 0.016 15.2 0.3 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF892) GAT PF03127.14 CCC70987.1 - 0.0097 16.2 3.5 0.045 14.1 3.5 2.2 1 0 0 1 1 1 1 GAT domain zf-AN1 PF01428.16 CCC70987.1 - 0.061 13.5 8.1 0.15 12.3 8.1 1.7 1 0 0 1 1 1 0 AN1-like Zinc finger Cyclin_N PF00134.23 CCC70988.1 - 4.7e-37 126.6 0.0 9.4e-37 125.6 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain VIT_2 PF13757.6 CCC70988.1 - 0.42 10.5 3.5 4.9 7.1 0.2 3.0 3 0 0 3 3 3 0 Vault protein inter-alpha-trypsin domain BBP1_C PF15272.6 CCC70989.1 - 2.7e-56 190.4 24.8 2.7e-56 190.4 24.8 1.7 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal BBP1_N PF15271.6 CCC70989.1 - 1.8e-38 132.8 4.3 1.8e-38 132.8 4.3 2.5 2 1 0 2 2 2 1 Spindle pole body component BBP1, Mps2-binding protein Golgin_A5 PF09787.9 CCC70989.1 - 0.012 15.1 21.8 0.043 13.3 8.8 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 SF1-HH PF16275.5 CCC70989.1 - 0.015 15.6 7.8 0.097 13.0 4.4 2.9 2 1 0 2 2 2 0 Splicing factor 1 helix-hairpin domain Pox_A_type_inc PF04508.12 CCC70989.1 - 0.95 9.4 5.1 29 4.7 5.1 2.6 1 1 0 1 1 1 0 Viral A-type inclusion protein repeat OEP PF02321.18 CCC70989.1 - 1.1 9.0 17.9 0.45 10.3 15.1 1.7 1 1 0 1 1 1 0 Outer membrane efflux protein FapA PF03961.13 CCC70989.1 - 2.3 6.7 14.2 0.25 9.9 3.3 2.0 1 1 1 2 2 2 0 Flagellar Assembly Protein A SAGA-Tad1 PF12767.7 CCC70990.1 - 2e-76 256.8 0.7 2.6e-76 256.5 0.2 1.4 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.14 CCC70990.1 - 0.001 18.9 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Microtub_bd PF16796.5 CCC70991.1 - 4.6e-25 88.3 3.1 4.6e-25 88.3 3.1 2.7 2 0 0 2 2 2 1 Microtubule binding Cob_adeno_trans PF01923.18 CCC70991.1 - 0.0048 17.0 19.1 0.073 13.2 0.7 3.6 1 1 3 4 4 4 3 Cobalamin adenosyltransferase TMEM132D_N PF15705.5 CCC70991.1 - 0.086 12.7 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term Csm1_N PF18504.1 CCC70991.1 - 0.13 12.7 22.2 4.9 7.6 10.0 4.2 2 1 1 3 3 3 0 Csm1 N-terminal domain DUF4407 PF14362.6 CCC70991.1 - 2 7.7 13.3 4.9 6.4 13.3 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) CENP-F_leu_zip PF10473.9 CCC70991.1 - 5.1 7.1 40.1 0.48 10.4 13.1 3.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.12 CCC70991.1 - 6.8 7.2 16.0 0.41 11.2 0.4 4.2 3 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Fer2 PF00111.27 CCC70992.1 - 4.4e-14 52.2 0.7 5.9e-14 51.8 0.7 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Glyco_hydro_63 PF03200.16 CCC70993.1 - 8e-06 24.9 11.8 0.0016 17.2 0.3 5.0 4 2 0 4 4 4 3 Glycosyl hydrolase family 63 C-terminal domain RRM PF10378.9 CCC70994.1 - 0.043 13.5 0.1 0.15 11.8 0.1 1.9 1 0 0 1 1 1 0 Putative RRM domain Ribosomal_L36e PF01158.18 CCC70995.1 - 1.3e-36 124.7 4.3 1.5e-36 124.5 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e TetR_C_9 PF14514.6 CCC70995.1 - 0.062 13.4 0.0 0.079 13.1 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain RabGAP-TBC PF00566.18 CCC70996.1 - 1.6e-50 171.7 0.5 1.6e-50 171.7 0.5 3.1 3 0 0 3 3 3 1 Rab-GTPase-TBC domain ADIP PF11559.8 CCC70996.1 - 0.0084 16.2 6.5 0.0084 16.2 6.5 4.1 4 1 0 4 4 4 1 Afadin- and alpha -actinin-Binding WD40_alt PF14077.6 CCC70996.1 - 0.12 12.2 2.3 0.43 10.5 2.3 2.0 1 0 0 1 1 1 0 Alternative WD40 repeat motif Fungal_trans PF04082.18 CCC70997.1 - 1.4e-23 83.3 11.5 3.1e-23 82.1 8.0 2.9 3 0 0 3 3 3 1 Fungal specific transcription factor domain Gal4_dimer PF03902.13 CCC70997.1 - 7e-09 35.7 0.6 2.4e-08 34.0 0.6 2.0 1 0 0 1 1 1 1 Gal4-like dimerisation domain Zn_clus PF00172.18 CCC70997.1 - 1.1e-07 31.9 18.9 1.9e-07 31.1 18.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ISN1 PF06437.11 CCC70997.1 - 0.08 11.8 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase RQC PF09382.10 CCC70998.1 - 2.2e-25 88.6 0.1 5.2e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 RQC domain Helicase_C PF00271.31 CCC70998.1 - 2.3e-22 79.4 0.6 2.5e-17 63.2 0.0 3.3 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 CCC70998.1 - 2.7e-22 79.4 0.0 6.3e-22 78.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 CCC70998.1 - 4.7e-15 56.0 8.5 8.7e-15 55.2 7.0 2.4 2 0 0 2 2 2 1 RecQ zinc-binding ResIII PF04851.15 CCC70998.1 - 4.6e-06 26.8 0.0 4.6e-06 26.8 0.0 3.1 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit HTH_51 PF18558.1 CCC70998.1 - 0.022 14.6 0.1 0.097 12.6 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain WD40 PF00400.32 CCC70999.1 - 2.5e-13 50.3 9.0 0.00024 21.8 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat Rhomboid PF01694.22 CCC71000.1 - 6.6e-18 65.1 14.0 1.2e-17 64.3 14.0 1.3 1 0 0 1 1 1 1 Rhomboid family LpxB PF02684.15 CCC71000.1 - 0.23 10.3 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase DUF2075 PF09848.9 CCC71001.1 - 1.1e-107 360.5 0.0 1.5e-107 360.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 CCC71001.1 - 2.9e-09 37.3 0.0 7.2e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 CCC71001.1 - 4.3e-05 23.9 0.0 9.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCC71001.1 - 0.00015 22.2 0.0 0.00041 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.14 CCC71001.1 - 0.0028 16.9 0.0 0.0038 16.5 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase ResIII PF04851.15 CCC71001.1 - 0.0038 17.2 0.4 1.8 8.5 0.1 2.4 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_30 PF13604.6 CCC71001.1 - 0.0055 16.4 0.0 0.029 14.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain DUF3466 PF11949.8 CCC71001.1 - 0.017 13.8 0.0 0.034 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) Adeno_IVa2 PF02456.15 CCC71001.1 - 0.02 13.7 0.0 0.042 12.6 0.0 1.5 1 0 0 1 1 1 0 Adenovirus IVa2 protein DUF815 PF05673.13 CCC71001.1 - 0.038 13.2 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 CCC71001.1 - 0.041 14.3 0.2 0.32 11.4 0.0 2.6 2 1 1 3 3 3 0 RNA helicase RsgA_GTPase PF03193.16 CCC71001.1 - 0.093 12.6 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase T2SSE PF00437.20 CCC71001.1 - 0.1 11.6 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 CCC71001.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.8 1 1 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 CCC71001.1 - 0.15 12.0 0.0 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 NTPase UAA PF08449.11 CCC71002.1 - 1.4e-36 126.2 18.1 1.7e-36 126.0 18.1 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.16 CCC71002.1 - 9.3e-07 28.5 14.0 0.0011 18.4 4.4 2.3 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 CCC71002.1 - 4.4e-05 23.7 12.3 4.4e-05 23.7 12.3 3.5 2 2 0 3 3 3 1 EamA-like transporter family Nuc_sug_transp PF04142.15 CCC71002.1 - 4.9e-05 22.7 10.8 0.0016 17.7 3.4 2.2 1 1 0 2 2 2 2 Nucleotide-sugar transporter SRP68 PF16969.5 CCC71003.1 - 1.2e-64 219.4 19.8 1.4e-64 219.1 19.8 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 L31 PF09784.9 CCC71003.1 - 5.3 7.5 7.1 0.51 10.8 0.2 2.9 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L31 RasGAP_C PF03836.15 CCC71004.1 - 1e-28 100.2 5.5 3.6e-28 98.4 5.5 2.1 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.19 CCC71004.1 - 6e-14 52.2 3.5 6e-14 52.2 3.5 2.8 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 CCC71004.1 - 1.5e-13 50.9 2.2 3.8e-13 49.6 0.0 2.9 4 0 0 4 4 4 1 Calponin homology (CH) domain NPV_P10 PF05531.12 CCC71004.1 - 0.0068 16.8 3.8 0.015 15.8 1.9 2.7 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein IQ PF00612.27 CCC71004.1 - 1.4 8.9 21.8 0.19 11.6 0.8 6.5 6 0 0 6 6 6 0 IQ calmodulin-binding motif TBCC PF07986.12 CCC71005.1 - 0.0007 19.3 1.2 0.069 12.9 1.2 2.3 1 1 1 2 2 2 2 Tubulin binding cofactor C TBCC_N PF16752.5 CCC71005.1 - 0.0012 19.3 0.4 0.0012 19.3 0.4 2.2 3 0 0 3 3 3 1 Tubulin-specific chaperone C N-terminal domain Coat_X PF07552.11 CCC71005.1 - 0.0036 17.1 0.1 0.013 15.3 0.1 1.9 1 0 0 1 1 1 1 Spore Coat Protein X and V domain Fez1 PF06818.15 CCC71005.1 - 0.088 13.3 3.4 0.12 12.8 3.4 1.3 1 0 0 1 1 1 0 Fez1 Ank_4 PF13637.6 CCC71006.1 - 5.6e-17 61.9 0.1 1.6e-11 44.5 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCC71006.1 - 3.3e-16 59.6 0.1 4.1e-15 56.1 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCC71006.1 - 3.6e-15 55.8 0.8 2.3e-08 34.1 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 CCC71006.1 - 2.1e-11 43.7 0.1 6.9e-06 26.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 CCC71006.1 - 1.1e-10 40.8 0.0 5.3e-05 23.3 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat eIF-5_eIF-2B PF01873.17 CCC71007.1 - 4e-38 129.9 0.1 8.3e-38 128.9 0.1 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.15 CCC71007.1 - 0.012 15.4 0.2 0.099 12.5 0.0 2.5 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region TF_Zn_Ribbon PF08271.12 CCC71007.1 - 0.028 13.9 0.2 0.058 12.9 0.2 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding DUF35_N PF12172.8 CCC71007.1 - 0.12 12.3 0.1 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Arc_trans_TRASH PF08394.10 CCC71007.1 - 3.2 8.2 5.8 29 5.1 1.9 2.7 1 1 1 2 2 2 0 Archaeal TRASH domain Pkinase PF00069.25 CCC71008.1 - 7.3e-22 78.0 0.0 1.3e-18 67.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71008.1 - 6.9e-11 41.9 0.0 4.2e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCC71008.1 - 0.057 12.7 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TIP49 PF06068.13 CCC71009.1 - 1.2e-156 521.3 1.0 1.6e-156 520.9 1.0 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 CCC71009.1 - 1.3e-24 86.1 0.8 4.5e-24 84.4 0.6 2.0 2 0 0 2 2 2 1 TIP49 AAA-lid domain AAA PF00004.29 CCC71009.1 - 7.9e-08 32.8 2.0 0.00011 22.6 0.1 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCC71009.1 - 4.1e-07 29.9 0.7 0.0033 17.2 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 CCC71009.1 - 1.4e-05 24.6 1.4 2.4e-05 23.8 0.2 1.9 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 CCC71009.1 - 3.1e-05 24.4 0.4 0.00014 22.3 0.4 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCC71009.1 - 0.0017 18.6 0.1 0.3 11.4 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.6 CCC71009.1 - 0.0021 18.4 0.4 0.016 15.6 0.4 2.3 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 CCC71009.1 - 0.0033 17.0 1.1 0.022 14.4 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 CCC71009.1 - 0.0088 16.3 0.1 0.032 14.5 0.1 2.0 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 CCC71009.1 - 0.016 14.6 0.8 0.2 11.0 0.3 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 CCC71009.1 - 0.025 14.6 0.5 2.1 8.3 0.1 2.9 2 2 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_C PF00137.21 CCC71010.1 - 2.7e-31 107.7 29.9 1.4e-18 67.0 8.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Mis14 PF08641.12 CCC71011.1 - 2.5e-39 134.6 4.5 2.5e-39 134.6 4.5 1.5 2 0 0 2 2 2 1 Kinetochore protein Mis14 like AAA_15 PF13175.6 CCC71011.1 - 0.047 13.4 2.9 0.087 12.5 2.9 1.4 1 1 0 1 1 1 0 AAA ATPase domain APP_E2 PF12925.7 CCC71011.1 - 0.053 13.2 0.2 0.092 12.4 0.2 1.4 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein HTH_Mga PF08280.11 CCC71011.1 - 0.088 12.9 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain bVLRF1 PF18826.1 CCC71011.1 - 0.12 12.3 0.1 0.21 11.5 0.1 1.4 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor DUF4559 PF15112.6 CCC71011.1 - 0.24 11.0 3.7 0.5 10.0 2.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Nbl1_Borealin_N PF10444.9 CCC71011.1 - 0.3 10.7 2.0 0.56 9.9 0.2 2.4 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal Syntaxin PF00804.25 CCC71012.1 - 1.5e-19 70.4 18.7 1.8e-19 70.3 15.6 2.3 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 CCC71012.1 - 7.1e-14 51.5 2.8 2.4e-13 49.9 2.8 2.0 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.21 CCC71012.1 - 9.9e-05 22.1 2.0 9.9e-05 22.1 2.0 2.5 2 1 1 3 3 3 1 Synaptobrevin LMBR1 PF04791.16 CCC71012.1 - 0.0097 14.9 4.2 0.012 14.5 4.2 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein SKA1 PF07160.12 CCC71012.1 - 0.013 15.4 3.2 0.013 15.4 3.2 2.3 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 T2SSF PF00482.23 CCC71012.1 - 0.062 13.2 2.3 0.2 11.6 2.3 1.9 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF5345 PF17280.2 CCC71012.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5345) VSG_B PF13206.6 CCC71012.1 - 0.68 9.1 6.2 2.1 7.5 6.4 1.6 2 0 0 2 2 2 0 Trypanosomal VSG domain ACCA PF03255.14 CCC71012.1 - 0.8 9.6 8.1 0.1 12.5 1.2 2.3 2 1 1 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4446 PF14584.6 CCC71012.1 - 1.3 9.0 0.0 1.3 9.0 0.0 4.3 3 2 1 4 4 3 0 Protein of unknown function (DUF4446) DUF745 PF05335.13 CCC71012.1 - 1.9 8.2 18.3 0.067 12.9 7.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF745) Orf78 PF06024.12 CCC71012.1 - 2.2 8.6 6.0 1.3 9.4 0.5 2.7 2 1 0 2 2 2 0 Orf78 (ac78) Baculo_PEP_C PF04513.12 CCC71012.1 - 2.3 8.3 14.7 0.67 10.0 2.6 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mod_r PF07200.13 CCC71012.1 - 4 7.5 22.0 1.3 9.2 6.1 3.1 2 2 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.12 CCC71012.1 - 6 6.9 12.1 7.6 6.6 4.6 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) DUF755 PF05501.11 CCC71012.1 - 9.5 6.5 13.7 37 4.6 1.7 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF755) PCRF PF03462.18 CCC71012.1 - 9.6 6.0 14.9 11 5.8 0.8 2.5 1 1 2 3 3 3 0 PCRF domain Fas_alpha_ACP PF18325.1 CCC71013.1 - 1.3e-72 243.4 0.1 4e-72 241.8 0.0 1.9 2 0 0 2 2 2 1 Fatty acid synthase subunit alpha Acyl carrier domain FAS_I_H PF18314.1 CCC71013.1 - 1.5e-65 220.7 1.1 2.7e-65 219.8 0.1 2.0 2 0 0 2 2 2 1 Fatty acid synthase type I helical domain ketoacyl-synt PF00109.26 CCC71013.1 - 5.9e-20 71.9 0.0 1.3e-19 70.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.20 CCC71013.1 - 2.1e-15 56.8 0.0 5.2e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.22 CCC71013.1 - 3.6e-12 46.4 0.0 8.9e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Phage_RpbA PF10789.9 CCC71013.1 - 0.53 10.4 1.9 0.67 10.0 0.2 2.0 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA zf-H2C2_2 PF13465.6 CCC71014.1 - 2.5e-10 40.3 1.7 2.5e-10 40.3 1.7 3.4 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.26 CCC71014.1 - 3.7e-10 39.7 9.4 1.8e-05 24.9 2.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC71014.1 - 1.1e-05 25.9 8.4 0.0013 19.3 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.6 CCC71014.1 - 8.3e-05 22.5 0.2 0.00025 21.0 0.2 1.8 1 0 0 1 1 1 1 C2H2-type zinc finger zf-met PF12874.7 CCC71014.1 - 0.0077 16.6 3.1 0.033 14.6 0.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_aberr PF17017.5 CCC71014.1 - 0.28 11.3 2.9 0.85 9.7 2.9 1.7 1 1 0 1 1 1 0 Aberrant zinc-finger zf-H2C2_5 PF13909.6 CCC71014.1 - 0.69 9.7 5.0 2.7 7.8 1.0 3.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain gag_pre-integrs PF13976.6 CCC71014.1 - 0.78 9.6 3.4 0.91 9.4 0.6 2.6 2 0 0 2 2 2 0 GAG-pre-integrase domain mRNA_triPase PF02940.15 CCC71015.1 - 7.5e-66 222.0 0.2 7.5e-66 222.0 0.2 1.7 2 0 0 2 2 2 1 mRNA capping enzyme, beta chain Glycos_transf_2 PF00535.26 CCC71016.1 - 1.4e-24 86.8 0.0 2.2e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 CCC71016.1 - 8.9e-07 29.0 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 CCC71016.1 - 3.4e-05 23.5 0.0 4.6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 CCC71016.1 - 0.00029 21.3 0.0 0.00051 20.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Globin PF00042.22 CCC71017.1 - 0.014 16.0 0.0 0.033 14.8 0.0 1.6 1 0 0 1 1 1 0 Globin Fib_alpha PF08702.10 CCC71018.1 - 0.0045 17.2 1.3 0.0045 17.2 1.3 3.7 4 1 1 5 5 5 1 Fibrinogen alpha/beta chain family EXOSC1 PF10447.9 CCC71019.1 - 4.6e-43 146.3 0.3 4.6e-43 146.3 0.3 2.1 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 CRAL_TRIO PF00650.20 CCC71020.1 - 6.7e-39 133.2 0.0 1.3e-38 132.2 0.0 1.5 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCC71020.1 - 1.7e-17 63.3 0.0 3.3e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain IP_trans PF02121.18 CCC71020.1 - 0.14 11.7 0.1 0.22 11.1 0.1 1.2 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein Elongin_A PF06881.11 CCC71021.1 - 1.3e-20 73.9 9.1 2.9e-18 66.3 9.1 2.3 1 1 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Prok-E2_A PF14457.6 CCC71021.1 - 0.11 12.1 0.0 3.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Prokaryotic E2 family A Totivirus_coat PF05518.11 CCC71021.1 - 0.17 9.9 5.4 0.25 9.3 5.4 1.2 1 0 0 1 1 1 0 Totivirus coat protein GST_C PF00043.25 CCC71022.1 - 1.7e-26 92.3 0.4 4.2e-26 91.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CCC71022.1 - 3.4e-20 72.2 0.0 1.1e-19 70.6 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CCC71022.1 - 3.3e-10 40.2 0.0 6.9e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 CCC71022.1 - 3.2e-09 37.0 0.0 7.8e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 CCC71022.1 - 4.7e-07 29.9 0.0 1.5e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 CCC71022.1 - 0.0018 18.3 0.0 0.0034 17.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pex14_N PF04695.13 CCC71022.1 - 0.29 11.8 14.5 0.49 11.0 14.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.22 CCC71022.1 - 0.55 9.4 3.6 0.71 9.0 3.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Ureide_permease PF07168.11 CCC71022.1 - 0.83 8.3 2.7 1.3 7.7 2.7 1.3 1 0 0 1 1 1 0 Ureide permease Roughex PF06020.11 CCC71022.1 - 0.88 8.6 8.6 1.3 8.0 8.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PA26 PF04636.13 CCC71022.1 - 2 7.2 10.2 3.2 6.6 10.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TFIIA PF03153.13 CCC71022.1 - 2.3 8.1 25.4 3.3 7.6 25.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BNIP2 PF12496.8 CCC71022.1 - 2.5 8.5 8.9 5.8 7.4 8.9 1.5 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Suf PF05843.14 CCC71022.1 - 2.7 7.9 16.0 4.1 7.3 16.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Androgen_recep PF02166.16 CCC71022.1 - 2.8 6.7 13.5 3.9 6.2 13.5 1.2 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 CCC71022.1 - 3.9 6.1 14.4 5 5.8 14.4 1.1 1 0 0 1 1 1 0 Presenilin SprA-related PF12118.8 CCC71022.1 - 4.5 6.3 21.1 6.6 5.8 21.1 1.1 1 0 0 1 1 1 0 SprA-related family RP-C_C PF11800.8 CCC71022.1 - 5.9 6.9 11.4 12 6.0 11.4 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Lin-8 PF03353.15 CCC71022.1 - 6.3 6.3 18.2 9.3 5.7 18.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Membralin PF09746.9 CCC71022.1 - 8 5.4 9.7 14 4.5 9.7 1.3 1 0 0 1 1 1 0 Tumour-associated protein DUF3682 PF12446.8 CCC71022.1 - 9.4 6.7 22.0 18 5.8 22.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DnaJ PF00226.31 CCC71023.1 - 5.7e-23 80.8 0.3 5.7e-23 80.8 0.3 2.6 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_2 PF12756.7 CCC71023.1 - 5.3e-09 36.3 2.4 0.00022 21.5 0.5 3.5 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 CCC71023.1 - 8.3e-08 32.3 6.2 8.3e-08 32.3 6.2 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CCC71023.1 - 7.5e-06 26.3 4.1 0.033 15.0 0.5 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCC71023.1 - 0.00035 20.8 3.4 0.00035 20.8 3.4 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 CCC71023.1 - 0.00077 19.8 7.1 0.03 14.8 1.3 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type AKAP95 PF04988.12 CCC71023.1 - 0.0027 18.0 2.0 0.0027 18.0 2.0 3.5 3 2 1 4 4 4 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.6 CCC71023.1 - 1.2 9.2 7.3 6.1 7.0 1.4 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger SID PF11778.8 CCC71024.1 - 1.7e-43 147.9 1.0 1.7e-43 147.9 1.0 2.1 2 0 0 2 2 2 1 Septation initiation Spc7 PF08317.11 CCC71024.1 - 0.0098 14.8 39.6 0.098 11.5 11.3 2.6 2 0 0 2 2 2 2 Spc7 kinetochore protein DUF1664 PF07889.12 CCC71024.1 - 0.017 15.2 22.3 0.67 10.0 2.5 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) HOOK PF05622.12 CCC71024.1 - 0.045 11.9 34.9 0.014 13.6 16.3 2.2 2 0 0 2 2 2 0 HOOK protein ATG16 PF08614.11 CCC71024.1 - 0.11 12.7 29.8 0.098 12.9 13.6 2.9 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 CCC71024.1 - 0.13 11.9 18.6 0.32 10.5 7.6 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit Golgin_A5 PF09787.9 CCC71024.1 - 0.22 10.9 35.4 0.51 9.7 15.6 3.0 2 1 0 2 2 2 0 Golgin subfamily A member 5 HMMR_N PF15905.5 CCC71024.1 - 0.38 10.2 39.6 1.4 8.3 18.4 2.4 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Jnk-SapK_ap_N PF09744.9 CCC71024.1 - 0.56 10.4 38.9 0.035 14.3 12.7 2.8 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 DASH_Dam1 PF08653.10 CCC71024.1 - 1.3 8.9 3.5 4.4 7.2 0.3 3.3 2 1 1 3 3 3 0 DASH complex subunit Dam1 DUF4407 PF14362.6 CCC71024.1 - 3.1 7.1 15.9 1.4 8.2 6.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Lectin_N PF03954.14 CCC71024.1 - 9.2 6.0 20.0 0.18 11.6 4.5 3.4 2 1 1 3 3 3 0 Hepatic lectin, N-terminal domain G-patch PF01585.23 CCC71025.1 - 1.3e-11 44.2 2.4 2.4e-11 43.3 2.4 1.5 1 0 0 1 1 1 1 G-patch domain R3H PF01424.22 CCC71025.1 - 0.0041 17.1 1.1 0.0066 16.4 0.0 2.0 2 0 0 2 2 2 1 R3H domain Peptidase_C54 PF03416.19 CCC71026.1 - 4.5e-85 285.4 0.0 5.9e-85 285.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.13 CCC71027.1 - 3.1e-84 281.3 0.0 3.5e-84 281.1 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein Hyphal_reg_CWP PF11765.8 CCC71028.1 - 2.1e-15 56.5 7.4 2.1e-15 56.5 7.4 1.9 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal DUF3755 PF12579.8 CCC71028.1 - 0.087 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3755) POP1 PF06978.11 CCC71029.1 - 5.9e-77 258.3 12.7 5.9e-77 258.3 12.7 2.1 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 CCC71029.1 - 3.1e-32 110.7 1.0 7.3e-32 109.6 1.0 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain HTH_Tnp_IS630 PF01710.16 CCC71029.1 - 0.063 13.3 1.3 2.6 8.1 1.6 2.6 2 0 0 2 2 2 0 Transposase Adenylsucc_synt PF00709.21 CCC71030.1 - 2.4e-176 586.8 0.0 2.7e-176 586.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase DUF1033 PF06279.11 CCC71030.1 - 0.3 11.2 0.5 0.97 9.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) Glyco_transf_22 PF03901.17 CCC71031.1 - 8.8e-90 301.9 37.5 1.5e-89 301.2 37.5 1.3 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family MgsA_C PF12002.8 CCC71032.1 - 2e-53 180.7 0.1 4.4e-53 179.6 0.1 1.5 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 CCC71032.1 - 4.1e-23 81.5 0.1 1.1e-22 80.1 0.1 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 CCC71032.1 - 2.1e-15 57.3 0.0 6.5e-15 55.7 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCC71032.1 - 1.9e-12 47.2 0.0 7.8e-12 45.2 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCC71032.1 - 2e-07 31.5 0.1 0.00063 20.2 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_14 PF13173.6 CCC71032.1 - 9.4e-07 28.9 0.0 2.4e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 CCC71032.1 - 3e-06 27.3 0.0 7.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 CCC71032.1 - 1.5e-05 24.8 0.0 7.4e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 CCC71032.1 - 2.2e-05 24.8 0.3 0.032 14.5 0.0 2.7 1 1 1 2 2 2 2 AAA domain Mg_chelatase PF01078.21 CCC71032.1 - 6.9e-05 22.3 0.1 0.42 10.0 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 CCC71032.1 - 0.0029 18.1 0.0 0.0063 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCC71032.1 - 0.0037 17.6 0.2 1 9.7 0.0 2.4 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 CCC71032.1 - 0.004 16.9 0.0 0.0072 16.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 CCC71032.1 - 0.0073 16.4 0.0 0.016 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 CCC71032.1 - 0.015 15.7 0.1 0.056 13.8 0.0 2.1 2 0 0 2 2 1 0 RNA helicase TniB PF05621.11 CCC71032.1 - 0.033 13.6 0.0 1.7 8.0 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 CCC71032.1 - 0.033 13.9 0.0 0.12 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 CCC71032.1 - 0.042 13.6 0.0 0.09 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 CCC71032.1 - 0.053 12.7 0.0 0.12 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 CCC71032.1 - 0.057 13.9 0.0 0.15 12.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter ResIII PF04851.15 CCC71032.1 - 0.072 13.1 0.2 1.3 9.0 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit hGDE_central PF14702.6 CCC71032.1 - 0.088 12.5 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Central domain of human glycogen debranching enzyme AAA_3 PF07726.11 CCC71032.1 - 0.14 12.0 0.0 0.76 9.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hpt PF01627.23 CCC71033.1 - 6.4e-11 42.4 0.0 9.5e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Lge1 PF11488.8 CCC71033.1 - 0.025 14.8 1.1 0.07 13.3 1.1 1.7 1 0 0 1 1 1 0 Transcriptional regulatory protein LGE1 TOM6p PF15184.6 CCC71033.1 - 0.14 12.0 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog Metallophos PF00149.28 CCC71034.1 - 6.6e-11 43.1 0.0 3.9e-10 40.6 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 CCC71034.1 - 0.0002 21.6 0.0 0.00035 20.8 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.6 CCC71034.1 - 0.016 14.6 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Rap1-DNA-bind PF09197.10 CCC71035.1 - 3.7e-44 149.7 9.8 4.2e-43 146.4 0.2 3.5 3 1 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.8 CCC71035.1 - 5.1e-22 77.8 0.0 3.3e-21 75.2 0.0 2.4 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain BRCT_2 PF16589.5 CCC71035.1 - 1.7e-17 63.6 0.0 7.4e-17 61.5 0.0 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Myb_DNA-binding PF00249.31 CCC71035.1 - 2.5e-13 50.0 0.2 6e-10 39.2 0.0 3.6 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_2 PF08914.11 CCC71035.1 - 7.3e-09 35.7 0.4 9.4e-05 22.5 0.0 3.0 3 0 0 3 3 3 2 Rap1 Myb domain LIG3_BRCT PF16759.5 CCC71035.1 - 0.016 15.5 0.2 0.072 13.4 0.0 2.2 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Myb_DNA-bind_6 PF13921.6 CCC71035.1 - 0.037 14.3 1.5 4.1 7.7 0.0 3.8 4 0 0 4 4 4 0 Myb-like DNA-binding domain SLIDE PF09111.10 CCC71035.1 - 0.043 13.8 3.6 0.32 11.0 0.6 3.3 3 1 0 3 3 3 0 SLIDE LIM_bind PF01803.16 CCC71036.1 - 1.3e-47 162.4 1.8 1.9e-47 161.9 1.8 1.3 1 0 0 1 1 1 1 LIM-domain binding protein Laminin_II PF06009.12 CCC71037.1 - 0.038 14.0 0.3 0.093 12.7 0.1 1.7 1 1 1 2 2 2 0 Laminin Domain II DUF1664 PF07889.12 CCC71037.1 - 0.12 12.4 0.0 0.28 11.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3502 PF12010.8 CCC71037.1 - 0.14 12.8 0.4 0.22 12.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3502) Neugrin PF06413.11 CCC71038.1 - 6.4e-10 39.4 0.8 1.3e-09 38.4 0.8 1.5 1 1 0 1 1 1 1 Neugrin Sigma70_r4 PF04545.16 CCC71038.1 - 0.00016 21.1 1.4 0.00038 19.9 0.1 2.1 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_11 PF08279.12 CCC71038.1 - 0.0013 18.7 0.0 0.0026 17.6 0.0 1.6 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.7 CCC71038.1 - 0.0026 17.6 0.0 0.0043 16.9 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_32 PF13565.6 CCC71038.1 - 0.012 16.2 0.9 0.028 15.0 0.1 2.1 3 0 0 3 3 3 0 Homeodomain-like domain HTH_7 PF02796.15 CCC71038.1 - 0.042 13.9 0.6 1.6 8.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase MarR PF01047.22 CCC71038.1 - 0.055 13.4 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 MarR family DUF5069 PF16798.5 CCC71038.1 - 0.1 12.8 0.8 0.27 11.4 0.0 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF5069) HTH_23 PF13384.6 CCC71038.1 - 0.13 12.1 0.4 2.5 8.0 0.0 2.6 3 0 0 3 3 3 0 Homeodomain-like domain HTH_31 PF13560.6 CCC71038.1 - 0.13 12.6 0.0 0.84 10.0 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain VID27 PF08553.10 CCC71039.1 - 3.9e-148 493.3 0.8 6.8e-148 492.5 0.8 1.4 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_N PF17748.1 CCC71039.1 - 2.9e-48 164.0 3.5 2.9e-48 164.0 3.5 3.1 3 0 0 3 3 3 1 VID27 N-terminal region VID27_PH PF17747.1 CCC71039.1 - 5.9e-29 100.5 4.2 2e-28 98.9 0.3 3.1 3 0 0 3 3 3 1 VID27 PH-like domain Mrx7 PF10906.8 CCC71040.1 - 7.4e-29 99.8 0.4 8.6e-29 99.6 0.4 1.1 1 0 0 1 1 1 1 MIOREX complex component 7 Ost4 PF10215.9 CCC71041.1 - 5.9e-15 54.8 2.6 6.3e-15 54.7 2.6 1.0 1 0 0 1 1 1 1 Oligosaccaryltransferase PRIMA1 PF16101.5 CCC71041.1 - 0.12 12.5 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 KH_1 PF00013.29 CCC71042.1 - 1.3e-06 28.1 0.0 3.7e-06 26.7 0.0 1.8 1 1 0 1 1 1 1 KH domain HSP70 PF00012.20 CCC71043.1 - 4.6e-230 764.9 8.5 5.2e-230 764.7 8.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCC71043.1 - 3.9e-17 62.1 0.7 1.2e-15 57.1 0.2 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CCC71043.1 - 0.00097 18.9 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 CCC71043.1 - 0.037 14.4 4.8 3.9 8.0 0.1 3.6 3 2 0 3 3 3 0 Cell division protein FtsA Zincin_2 PF10103.9 CCC71043.1 - 0.067 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Rick_17kDa_Anti PF05433.15 CCC71044.1 - 6.2e-09 35.6 2.7 6.2e-09 35.6 2.7 2.1 2 0 0 2 2 2 1 Glycine zipper 2TM domain RIO1 PF01163.22 CCC71045.1 - 1.1e-42 145.7 0.3 1.8e-42 145.1 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 CCC71045.1 - 1.2e-31 108.8 0.1 2.4e-31 107.8 0.1 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 CCC71045.1 - 3.8e-06 27.0 0.1 0.097 12.6 0.4 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CCC71045.1 - 0.00039 19.8 0.1 0.012 15.0 0.1 2.2 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 CCC71045.1 - 0.021 13.6 0.0 0.021 13.6 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase DNA_pol_phi PF04931.13 CCC71045.1 - 1.8 6.5 21.0 2.6 6.0 21.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 CCC71045.1 - 2.1 6.5 16.1 2.7 6.1 16.1 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 CCC71045.1 - 3.5 7.5 12.1 4.7 7.1 12.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pox_Ag35 PF03286.14 CCC71045.1 - 3.7 7.3 8.5 6.9 6.4 8.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BUD22 PF09073.10 CCC71045.1 - 4.9 6.4 12.1 6.9 5.9 12.1 1.1 1 0 0 1 1 1 0 BUD22 PH_18 PF18469.1 CCC71046.1 - 3.6e-49 166.4 2.5 3.6e-49 166.4 2.5 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Rtt106_N PF18215.1 CCC71046.1 - 6.4e-29 99.4 1.4 1e-28 98.8 0.1 2.1 2 0 0 2 2 2 1 Histone chaperone Rtt106 N-terminal domain Rtt106 PF08512.12 CCC71046.1 - 2.2e-28 98.5 1.5 4.6e-28 97.5 0.6 2.0 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SLC12 PF03522.15 CCC71046.1 - 0.017 14.1 7.4 0.027 13.5 7.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Pes-10 PF07149.11 CCC71046.1 - 0.053 12.6 18.7 0.087 11.9 18.7 1.3 1 0 0 1 1 1 0 Pes-10 Nop25 PF09805.9 CCC71046.1 - 0.29 11.6 20.9 0.81 10.1 20.9 1.9 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) CobT PF06213.12 CCC71046.1 - 0.71 9.2 23.3 1.4 8.3 23.3 1.5 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Raftlin PF15250.6 CCC71046.1 - 1.3 7.7 12.5 2.1 7.0 12.5 1.2 1 0 0 1 1 1 0 Raftlin BUD22 PF09073.10 CCC71046.1 - 3.3 6.9 28.3 5.9 6.1 28.3 1.4 1 0 0 1 1 1 0 BUD22 Na_trans_assoc PF06512.13 CCC71046.1 - 9.2 6.5 21.4 20 5.4 21.4 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated adh_short_C2 PF13561.6 CCC71047.1 - 3.3e-43 147.9 0.0 4.1e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 CCC71047.1 - 2.2e-30 105.6 0.0 3.3e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 CCC71047.1 - 2.8e-06 27.4 0.0 4.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 CCC71047.1 - 0.17 11.0 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SMK-1 PF04802.15 CCC71048.1 - 3.5e-61 206.4 9.2 3.5e-61 206.4 9.2 2.6 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 YjeF_N PF03853.15 CCC71050.1 - 4.8e-36 124.2 0.0 5.7e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Endotoxin_C PF03944.14 CCC71050.1 - 0.08 13.3 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 delta endotoxin DUF429 PF04250.13 CCC71050.1 - 0.25 11.1 0.0 0.35 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF429) NYD-SP28 PF14772.6 CCC71051.1 - 0.017 15.2 10.1 0.31 11.1 0.5 2.9 3 1 0 3 3 3 0 Sperm tail HIP1_clath_bdg PF16515.5 CCC71051.1 - 3.6 8.3 8.7 0.31 11.7 0.3 2.9 2 1 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 ADH_zinc_N PF00107.26 CCC71052.1 - 5.9e-14 52.2 0.0 9.8e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCC71052.1 - 5.8e-05 22.9 0.1 0.00082 19.2 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CCC71052.1 - 0.045 14.8 0.1 0.081 14.0 0.1 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TrkA_N PF02254.18 CCC71052.1 - 0.12 12.7 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain RRM_1 PF00076.22 CCC71053.1 - 5e-15 55.1 0.0 7.2e-09 35.3 0.0 3.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3213 PF11491.8 CCC71055.1 - 0.0016 18.6 0.1 0.0032 17.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) SUR7 PF06687.12 CCC71056.1 - 2.5e-29 102.4 19.3 3e-29 102.2 19.3 1.0 1 0 0 1 1 1 1 SUR7/PalI family SPC25 PF06703.11 CCC71056.1 - 0.6 9.9 2.6 0.77 9.5 1.3 1.8 1 1 1 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) Chitin_synth_1 PF01644.17 CCC71059.1 - 2.8e-68 229.0 1.2 4.5e-68 228.3 1.2 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.11 CCC71059.1 - 1.5e-25 89.0 0.2 3.8e-25 87.6 0.2 1.8 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.15 CCC71059.1 - 2e-18 66.4 3.8 1.7e-13 50.1 0.5 2.4 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 CCC71059.1 - 4e-11 43.2 0.8 4e-11 43.2 0.8 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 CCC71059.1 - 0.006 16.5 0.0 0.017 15.0 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 CCC71059.1 - 0.062 13.1 0.0 9.3 6.0 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family 2 GATase_4 PF13230.6 CCC71060.1 - 4.9e-15 55.2 0.0 1.3e-13 50.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.6 CCC71060.1 - 1.2e-10 41.7 0.0 2.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 CCC71060.1 - 0.042 13.7 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferase domain Chordopox_A13L PF05961.11 CCC71062.1 - 1.7 9.0 9.0 16 5.8 0.4 3.5 1 1 4 5 5 5 0 Chordopoxvirus A13L protein DUF1651 PF07864.11 CCC71062.1 - 1.8 9.0 6.1 44 4.5 0.3 3.7 1 1 4 5 5 5 0 Protein of unknown function (DUF1651) Arm PF00514.23 CCC71063.1 - 2.8e-84 274.9 20.4 4.6e-13 48.7 0.0 8.9 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 CCC71063.1 - 2.1e-28 98.6 8.7 6e-28 97.1 8.7 1.9 1 0 0 1 1 1 1 Importin beta binding domain Arm_3 PF16186.5 CCC71063.1 - 1.4e-20 72.6 3.2 5.2e-20 70.8 3.1 2.1 2 0 0 2 2 2 1 Atypical Arm repeat HEAT_EZ PF13513.6 CCC71063.1 - 5.7e-18 65.0 3.8 5.6e-06 26.7 0.1 6.7 6 2 2 8 8 7 5 HEAT-like repeat HEAT_2 PF13646.6 CCC71063.1 - 5.9e-14 52.2 0.2 0.0028 18.0 0.0 4.5 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.22 CCC71063.1 - 6.5e-12 44.6 0.0 0.52 10.7 0.0 7.3 7 0 0 7 7 7 2 HEAT repeat RICTOR_V PF14668.6 CCC71063.1 - 1.2e-05 25.4 2.5 0.058 13.6 0.0 5.0 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.8 CCC71063.1 - 1.7e-05 24.9 1.3 1.6 8.8 0.0 4.5 2 2 5 8 8 8 3 V-ATPase subunit H HEAT_PBS PF03130.16 CCC71063.1 - 0.003 18.1 3.1 11 7.1 0.0 4.8 5 0 0 5 5 3 1 PBS lyase HEAT-like repeat Adaptin_N PF01602.20 CCC71063.1 - 0.018 13.7 0.1 0.14 10.6 0.1 2.4 1 1 1 2 2 2 0 Adaptin N terminal region O-FucT PF10250.9 CCC71063.1 - 0.035 13.8 0.9 0.057 13.1 0.9 1.3 1 0 0 1 1 1 0 GDP-fucose protein O-fucosyltransferase SAPS PF04499.15 CCC71063.1 - 0.077 11.8 5.0 0.031 13.1 1.6 2.1 3 1 0 3 3 3 0 SIT4 phosphatase-associated protein Atx10homo_assoc PF09759.9 CCC71063.1 - 0.097 12.7 2.9 2.7 8.1 0.0 4.3 5 1 1 6 6 6 0 Spinocerebellar ataxia type 10 protein domain TFIIE-A_C PF11521.8 CCC71063.1 - 0.13 12.6 1.3 0.3 11.4 1.3 1.6 1 0 0 1 1 1 0 C-terminal general transcription factor TFIIE alpha DUF3552 PF12072.8 CCC71063.1 - 0.35 10.2 7.6 0.65 9.4 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SlyX PF04102.12 CCC71063.1 - 3.1 8.5 8.3 4.1 8.1 7.2 1.8 1 1 0 1 1 1 0 SlyX Tim17 PF02466.19 CCC71065.1 - 3.3e-36 124.0 5.6 4.3e-36 123.7 5.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Serine_protease PF18405.1 CCC71065.1 - 0.033 13.3 0.1 0.046 12.9 0.1 1.4 1 1 0 1 1 1 0 Gammaproteobacterial serine protease UCH PF00443.29 CCC71067.1 - 1.8e-49 168.6 3.0 1.8e-49 168.6 3.0 2.7 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCC71067.1 - 4.4e-19 69.2 4.3 4.4e-19 69.2 4.3 3.8 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-BED PF02892.15 CCC71067.1 - 0.046 13.8 0.4 2.1 8.4 0.1 2.9 2 0 0 2 2 2 0 BED zinc finger Prenyltrans PF00432.21 CCC71067.1 - 0.22 11.3 0.0 0.53 10.1 0.0 1.6 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Ribosomal_L11 PF00298.19 CCC71068.1 - 1.9e-27 95.5 0.1 2.9e-27 95.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.14 CCC71068.1 - 1.4e-23 82.5 0.4 2.2e-23 81.8 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.25 CCC71069.1 - 2.4e-46 158.3 0.0 3.6e-46 157.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71069.1 - 2.2e-22 79.6 0.0 4e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 CCC71069.1 - 0.023 13.7 0.1 0.023 13.7 0.1 2.4 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 CCC71069.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like ANAPC4_WD40 PF12894.7 CCC71070.1 - 1.6e-05 25.1 0.2 0.017 15.4 0.0 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCC71070.1 - 6.1e-05 23.7 1.4 2.8 8.9 0.0 5.1 6 1 0 6 6 6 2 WD domain, G-beta repeat HPS3_N PF14761.6 CCC71070.1 - 0.0053 16.3 0.1 0.28 10.7 0.1 2.8 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3 DASH_Dam1 PF08653.10 CCC71070.1 - 0.048 13.5 0.2 0.14 12.0 0.2 1.8 1 0 0 1 1 1 0 DASH complex subunit Dam1 Fzo_mitofusin PF04799.13 CCC71070.1 - 0.18 11.4 1.1 0.38 10.3 1.1 1.5 1 0 0 1 1 1 0 fzo-like conserved region ZapB PF06005.12 CCC71070.1 - 0.22 12.0 2.6 0.5 10.8 2.6 1.6 1 0 0 1 1 1 0 Cell division protein ZapB Bap31_Bap29_C PF18035.1 CCC71070.1 - 0.33 11.0 3.4 0.9 9.6 3.4 1.8 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain bZIP_1 PF00170.21 CCC71070.1 - 0.72 10.0 5.0 1.5 9.0 5.0 1.5 1 0 0 1 1 1 0 bZIP transcription factor Phage_int_SAM_5 PF13102.6 CCC71074.1 - 0.1 13.0 1.9 1 9.8 0.1 2.6 2 0 0 2 2 2 0 Phage integrase SAM-like domain adh_short PF00106.25 CCC71077.1 - 3.4e-07 29.9 0.0 3.5e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCC71077.1 - 2.7e-06 27.1 0.0 4.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCC71077.1 - 2.7e-05 24.2 0.0 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Bac_rhodopsin PF01036.18 CCC71077.1 - 0.14 11.8 0.2 0.14 11.8 0.2 1.5 2 0 0 2 2 2 0 Bacteriorhodopsin-like protein Ras PF00071.22 CCC71078.1 - 3.3e-45 153.6 0.0 6.2e-45 152.7 0.0 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 CCC71078.1 - 7.3e-20 71.4 0.0 4.6e-19 68.8 0.0 2.5 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC71078.1 - 5.8e-05 22.6 0.1 0.0005 19.6 0.1 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 CCC71078.1 - 0.0015 18.1 0.8 0.0036 16.9 0.0 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CCC71078.1 - 0.043 13.9 0.0 0.19 11.8 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 CCC71078.1 - 0.09 13.2 0.0 0.17 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain DUF2981 PF11200.8 CCC71078.1 - 0.16 11.7 1.9 0.23 11.2 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Neur_chan_memb PF02932.16 CCC71078.1 - 3.6 7.6 8.3 5.2 7.1 8.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 CCC71078.1 - 5.5 6.1 9.4 9 5.4 9.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter LAM_C PF12544.8 CCC71078.1 - 5.9 7.1 9.3 0.28 11.4 1.5 2.6 2 1 1 3 3 3 0 Lysine-2,3-aminomutase Ribosomal_S3_C PF00189.20 CCC71079.1 - 2.7e-23 82.3 0.3 1.5e-22 79.9 0.4 2.1 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 CCC71079.1 - 6e-12 45.2 0.0 2.9e-11 43.0 0.1 2.0 2 0 0 2 2 2 1 KH domain Ribosomal_L22 PF00237.19 CCC71080.1 - 2.6e-23 82.2 0.0 4e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Gly-zipper_Omp PF13488.6 CCC71081.1 - 0.084 12.9 1.1 0.2 11.6 1.1 1.6 1 0 0 1 1 1 0 Glycine zipper Beta-APP PF03494.13 CCC71081.1 - 0.71 9.8 5.1 1.9 8.4 5.1 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) RRM_1 PF00076.22 CCC71082.1 - 3e-27 94.2 2.4 1.5e-16 60.0 0.1 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC71082.1 - 0.00037 20.6 0.1 0.64 10.2 0.0 2.9 2 2 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 CCC71082.1 - 0.0016 18.4 0.1 0.0052 16.8 0.0 1.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif AMPK1_CBM PF16561.5 CCC71083.1 - 3.5e-12 46.4 4.1 9.4e-12 45.0 4.1 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase ANAPC1 PF12859.7 CCC71084.1 - 1.3e-09 38.7 3.9 7.7e-09 36.2 0.4 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 PS_Dcarbxylase PF02666.15 CCC71085.1 - 3e-70 235.9 0.0 4.6e-70 235.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase FAA_hydrolase PF01557.18 CCC71086.1 - 6.7e-44 150.1 0.0 8.4e-44 149.8 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family bZIP_1 PF00170.21 CCC71087.1 - 4.4e-06 26.7 3.5 4.4e-06 26.7 3.5 2.0 2 0 0 2 2 2 1 bZIP transcription factor Aft1_OSA PF11785.8 CCC71087.1 - 9.1e-06 26.0 1.2 9.1e-06 26.0 1.2 2.8 2 0 0 2 2 2 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.15 CCC71087.1 - 0.0042 17.1 6.4 0.0089 16.1 6.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper DUF2441 PF10386.9 CCC71090.1 - 0.07 13.1 1.3 0.13 12.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2441) GTP_EFTU PF00009.27 CCC71091.1 - 1.2e-57 194.6 0.0 2.5e-57 193.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 CCC71091.1 - 2e-13 50.2 0.4 6.8e-13 48.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCC71091.1 - 3.4e-08 33.8 0.0 9.6e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CCC71091.1 - 6.7e-08 32.5 0.0 1.6e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.18 CCC71091.1 - 0.003 17.3 0.0 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G, domain IV MMR_HSR1 PF01926.23 CCC71091.1 - 0.0055 16.8 0.0 0.021 14.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Lar_restr_allev PF14354.6 CCC71092.1 - 0.037 14.4 0.8 0.052 13.9 0.8 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.11 CCC71092.1 - 0.096 12.6 0.7 0.13 12.2 0.7 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.10 CCC71092.1 - 0.15 12.2 3.4 0.46 10.7 0.8 2.3 2 1 0 2 2 2 0 Zinc ribbon domain IBR PF01485.21 CCC71092.1 - 0.21 11.9 3.8 0.63 10.3 0.4 2.1 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain UPF0547 PF10571.9 CCC71092.1 - 0.25 11.5 4.0 2.6 8.2 0.1 2.7 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-ribbon_3 PF13248.6 CCC71092.1 - 0.44 10.0 0.2 0.44 10.0 0.2 2.7 2 1 0 2 2 2 0 zinc-ribbon domain Ribosomal_L44 PF00935.19 CCC71093.1 - 7.7e-36 122.4 11.1 1.1e-35 121.9 11.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Pkinase PF00069.25 CCC71094.1 - 1.4e-61 208.2 0.2 2.1e-41 142.1 0.2 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71094.1 - 8.1e-27 94.1 0.3 4.3e-20 72.1 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 CCC71094.1 - 8.4e-05 21.7 0.2 8.4e-05 21.7 0.2 2.3 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 CCC71094.1 - 0.00037 19.9 0.5 0.0056 16.1 0.0 2.5 2 1 1 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCC71094.1 - 0.0053 16.7 0.2 0.69 9.8 0.1 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 CCC71094.1 - 0.026 13.6 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 CCC71094.1 - 0.11 11.2 0.0 0.11 11.2 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Asparaginase_C PF17763.1 CCC71095.1 - 0.025 14.8 0.1 0.72 10.1 0.1 2.7 1 1 0 1 1 1 0 Glutaminase/Asparaginase C-terminal domain Ammonium_transp PF00909.21 CCC71096.1 - 2.4e-122 408.5 27.2 2.7e-122 408.3 27.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Prefoldin_2 PF01920.20 CCC71097.1 - 1.4e-21 76.4 14.2 1.7e-21 76.1 14.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Spc7 PF08317.11 CCC71097.1 - 0.034 13.0 9.2 0.045 12.6 9.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Laminin_II PF06009.12 CCC71097.1 - 0.45 10.5 4.7 0.87 9.6 4.7 1.6 1 1 0 1 1 1 0 Laminin Domain II DivIC PF04977.15 CCC71097.1 - 1.1 9.1 13.2 0.6 9.9 1.5 2.2 1 1 1 2 2 2 0 Septum formation initiator SlyX PF04102.12 CCC71097.1 - 2.2 9.0 8.1 0.39 11.4 0.4 2.6 2 1 0 2 2 2 0 SlyX APG6_N PF17675.1 CCC71097.1 - 3.8 8.1 14.9 8.4 6.9 5.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region A_deaminase PF00962.22 CCC71098.1 - 6.5e-94 314.9 0.0 7.4e-94 314.7 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Cpn60_TCP1 PF00118.24 CCC71098.1 - 0.14 10.7 0.0 0.28 9.7 0.0 1.4 1 1 0 1 1 1 0 TCP-1/cpn60 chaperonin family MatP_C PF17414.2 CCC71098.1 - 0.15 12.3 0.0 11 6.3 0.0 2.7 2 0 0 2 2 2 0 MatP C-terminal ribbon-helix-helix domain Pkinase PF00069.25 CCC71099.1 - 5.6e-25 88.2 0.1 1.1e-24 87.2 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71099.1 - 8.3e-13 48.2 0.0 1.8e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC71099.1 - 5.8e-09 35.2 0.0 5.8e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CCC71099.1 - 0.00023 20.6 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCC71099.1 - 0.36 10.7 4.3 1.4 8.7 0.2 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family zf-AN1 PF01428.16 CCC71100.1 - 2.3e-10 40.4 11.5 2.3e-10 40.4 11.5 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger INSIG PF07281.12 CCC71101.1 - 9.2e-31 107.1 11.2 8e-28 97.5 3.6 2.1 1 1 1 2 2 2 2 Insulin-induced protein (INSIG) Pga1 PF10333.9 CCC71102.1 - 1e-28 100.4 1.9 1.4e-28 100.0 1.9 1.1 1 0 0 1 1 1 1 GPI-Mannosyltransferase II co-activator Chordopox_L2 PF05803.12 CCC71103.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.2 2 1 0 2 2 2 0 Chordopoxvirus L2 protein Phage_prot_Gp6 PF05133.14 CCC71103.1 - 0.14 11.2 0.0 14 4.7 0.0 2.0 2 0 0 2 2 2 0 Phage portal protein, SPP1 Gp6-like MFA1_2 PF17317.2 CCC71105.1 - 1.9e-23 81.9 0.2 2e-23 81.8 0.2 1.0 1 0 0 1 1 1 1 Mating hormone A-factor 1&2 LOR PF04525.12 CCC71105.1 - 0.15 11.6 0.0 0.15 11.6 0.0 1.0 1 0 0 1 1 1 0 LURP-one-related DUF782 PF05614.11 CCC71106.1 - 0.024 15.0 0.0 0.03 14.7 0.0 1.2 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) DUF2009 PF09418.10 CCC71107.1 - 1.9e-207 689.8 3.2 1.9e-207 689.8 3.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2009) zf-B_box PF00643.24 CCC71107.1 - 1.7e-06 28.1 4.0 3e-06 27.3 4.0 1.4 1 0 0 1 1 1 1 B-box zinc finger CEBP_ZZ PF16366.5 CCC71107.1 - 0.0017 18.5 2.9 0.0039 17.4 2.9 1.5 1 0 0 1 1 1 1 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 CCC71107.1 - 0.0047 17.1 1.3 0.012 15.8 1.3 1.7 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain zf-C3HC4_3 PF13920.6 CCC71107.1 - 0.43 10.5 6.0 0.81 9.6 6.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pyr_excise PF03013.14 CCC71107.1 - 1.6 8.7 6.6 21 5.1 1.9 3.4 2 1 1 3 3 3 0 Pyrimidine dimer DNA glycosylase DUF2681 PF10883.8 CCC71107.1 - 7.1 7.1 9.1 3.3 8.2 6.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) PGA2 PF07543.12 CCC71109.1 - 1.7e-13 50.8 9.9 1.9e-06 27.9 0.2 2.0 1 1 1 2 2 2 2 Protein trafficking PGA2 RapA_C PF12137.8 CCC71109.1 - 0.0086 15.1 0.6 0.01 14.9 0.6 1.1 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal Ferritin PF00210.24 CCC71109.1 - 0.13 12.2 2.4 0.19 11.7 2.4 1.3 1 1 0 1 1 1 0 Ferritin-like domain DUF1378 PF07125.11 CCC71109.1 - 0.2 11.8 1.5 0.87 9.8 0.2 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1378) YqzH PF14164.6 CCC71109.1 - 0.87 9.7 7.0 1.4 9.0 2.3 2.7 2 1 1 3 3 3 0 YqzH-like protein COX16 PF14138.6 CCC71109.1 - 1.5 9.4 5.8 0.68 10.5 2.5 1.9 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DivIC PF04977.15 CCC71109.1 - 2.2 8.1 8.0 14 5.6 0.1 2.3 1 1 1 2 2 2 0 Septum formation initiator RNA_pol_3_Rpc31 PF11705.8 CCC71110.1 - 1.1e-55 189.3 13.2 1.1e-55 189.3 13.2 1.4 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 C2 PF00168.30 CCC71111.1 - 1.1e-07 32.0 0.0 2.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain Phage_F PF02305.17 CCC71111.1 - 0.038 12.8 0.4 0.053 12.3 0.4 1.2 1 0 0 1 1 1 0 Capsid protein (F protein) THOC2_N PF16134.5 CCC71112.1 - 1.5e-169 565.7 11.6 1.5e-169 565.7 11.6 1.8 2 0 0 2 2 2 1 THO complex subunit 2 N-terminus Tho2 PF11262.8 CCC71112.1 - 2e-39 135.6 6.4 1.7e-27 96.4 5.3 4.2 4 0 0 4 4 4 3 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.8 CCC71112.1 - 4e-24 84.5 0.3 1.1e-23 83.0 0.3 1.9 1 0 0 1 1 1 1 Transcription- and export-related complex subunit SF3b10 PF07189.11 CCC71113.1 - 3.6e-28 97.5 2.5 4.6e-28 97.1 2.5 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DeoRC PF00455.22 CCC71113.1 - 0.036 14.0 0.1 0.042 13.8 0.1 1.1 1 0 0 1 1 1 0 DeoR C terminal sensor domain CAP_N PF01213.19 CCC71115.1 - 3.3e-114 381.7 8.3 4.2e-114 381.3 8.3 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 CCC71115.1 - 2e-62 209.4 0.7 4.4e-62 208.4 0.8 1.5 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 CCC71115.1 - 0.06 13.1 1.9 1 9.1 0.5 2.5 2 1 0 2 2 2 0 Tubulin binding cofactor C MecA PF05389.12 CCC71115.1 - 0.1 12.2 4.1 0.065 12.9 1.7 1.9 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) S4 PF01479.25 CCC71116.1 - 7.2e-16 57.6 0.0 1.4e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.6 CCC71116.1 - 0.0035 17.1 0.0 0.0092 15.8 0.0 1.6 1 0 0 1 1 1 1 S4 domain KapB PF08810.10 CCC71116.1 - 0.043 14.0 5.8 0.062 13.5 0.3 2.7 2 0 0 2 2 2 0 Kinase associated protein B GCK PF07802.11 CCC71116.1 - 0.52 10.8 3.3 3 8.3 1.4 2.6 2 0 0 2 2 2 0 GCK domain Eaf7 PF07904.13 CCC71117.1 - 1.1e-40 138.3 0.2 1.1e-40 138.3 0.2 3.3 2 1 0 2 2 2 1 Chromatin modification-related protein EAF7 FKBP_C PF00254.28 CCC71118.1 - 6.7e-33 112.9 0.0 7.8e-33 112.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ADH_zinc_N PF00107.26 CCC71119.1 - 3.2e-14 53.0 0.0 5.2e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCC71119.1 - 0.00023 21.0 0.3 0.004 17.0 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 CCC71119.1 - 0.0075 17.3 0.0 0.019 16.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 CCC71119.1 - 0.018 15.4 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain rve PF00665.26 CCC71120.1 - 1.1e-15 57.9 0.1 3.1e-14 53.2 0.0 2.7 2 0 0 2 2 2 1 Integrase core domain RT_RNaseH PF17917.1 CCC71120.1 - 4e-13 49.5 0.0 1.7e-12 47.6 0.0 2.1 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 CCC71120.1 - 2.4e-08 33.9 0.0 8.7e-08 32.1 0.0 1.9 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase MLVIN_C PF18697.1 CCC71120.1 - 0.0034 17.5 0.1 0.017 15.2 0.1 2.2 2 0 0 2 2 2 1 Murine leukemia virus (MLV) integrase (IN) C-terminal domain RVT_3 PF13456.6 CCC71120.1 - 0.15 11.9 0.0 0.48 10.2 0.0 1.9 1 0 0 1 1 1 0 Reverse transcriptase-like Mucin PF01456.17 CCC71120.1 - 8.9 6.3 23.6 14 5.6 23.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RVT_1 PF00078.27 CCC71121.1 - 2.5e-16 59.9 0.0 9.2e-15 54.8 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.14 CCC71121.1 - 0.0044 16.7 0.2 0.12 12.0 0.2 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) GNAT_acetyltr_2 PF13718.6 CCC71122.1 - 2.4e-99 331.3 0.9 1.2e-98 329.1 0.0 2.5 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 CCC71122.1 - 3.1e-93 311.8 9.7 6.4e-93 310.8 9.7 1.6 1 0 0 1 1 1 1 Possible tRNA binding domain Helicase_RecD PF05127.14 CCC71122.1 - 5.4e-65 218.5 0.0 2.3e-64 216.5 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 CCC71122.1 - 1e-33 115.1 0.4 3.2e-33 113.5 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) Sigma70_r4_2 PF08281.12 CCC71122.1 - 0.008 15.8 1.3 0.36 10.5 0.0 3.2 3 0 0 3 3 3 1 Sigma-70, region 4 AAA_22 PF13401.6 CCC71122.1 - 0.01 16.1 0.0 0.31 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain SurA_N_2 PF13623.6 CCC71122.1 - 0.054 13.4 0.7 0.12 12.3 0.7 1.5 1 0 0 1 1 1 0 SurA N-terminal domain AAA_19 PF13245.6 CCC71122.1 - 0.065 13.6 0.1 1.2 9.5 0.0 3.1 3 1 0 3 3 3 0 AAA domain DEAD PF00270.29 CCC71122.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase Tom22 PF04281.13 CCC71123.1 - 2.1e-49 166.9 0.6 2.3e-49 166.7 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF3169 PF11368.8 CCC71123.1 - 0.043 13.3 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Adeno_terminal PF02459.15 CCC71123.1 - 0.11 10.9 0.2 0.13 10.6 0.2 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein CDP-OH_P_transf PF01066.21 CCC71124.1 - 3.4e-16 59.8 0.1 3.4e-16 59.8 0.1 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase MTBP_N PF14918.6 CCC71124.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 MDM2-binding AAA_18 PF13238.6 CCC71125.1 - 0.00016 22.2 0.0 0.00083 19.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 CCC71125.1 - 0.023 13.9 0.0 0.029 13.6 0.0 1.3 1 1 0 1 1 1 0 G-protein alpha subunit tRNA_lig_kinase PF08303.11 CCC71125.1 - 0.039 14.1 0.3 0.45 10.6 0.3 2.1 1 1 0 1 1 1 0 tRNA ligase kinase domain AAA_33 PF13671.6 CCC71125.1 - 0.083 13.1 0.0 0.22 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 CCC71125.1 - 0.094 13.0 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain CPT PF07931.12 CCC71125.1 - 0.11 12.4 0.0 0.36 10.6 0.0 1.8 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 CCC71125.1 - 0.11 13.0 0.2 0.19 12.3 0.2 1.5 1 1 0 1 1 1 0 ABC transporter DSPc PF00782.20 CCC71126.1 - 1e-09 38.3 0.0 2.5e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCC71126.1 - 0.013 15.1 0.0 0.03 13.9 0.0 1.6 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CCC71126.1 - 0.016 15.3 0.0 0.034 14.3 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 CCC71126.1 - 0.077 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF2732 PF10809.8 CCC71126.1 - 0.091 12.6 0.0 16 5.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2732) AD PF09793.9 CCC71127.1 - 2.4e-22 78.9 0.1 3.6e-22 78.3 0.1 1.3 1 0 0 1 1 1 1 Anticodon-binding domain LSM14 PF12701.7 CCC71127.1 - 0.034 14.3 0.7 0.15 12.2 0.7 2.1 1 1 0 1 1 1 0 Scd6-like Sm domain DUF1967 PF09269.11 CCC71127.1 - 0.079 12.9 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) N1221 PF07923.13 CCC71128.1 - 1.2e-65 221.6 2.3 1.2e-65 221.6 2.3 1.9 2 0 0 2 2 2 1 N1221-like protein DUF3402 PF11882.8 CCC71128.1 - 9.2e-58 196.4 12.5 1.6e-30 106.6 4.4 3.3 1 1 1 2 2 2 2 Domain of unknown function (DUF3402) MFS_1 PF07690.16 CCC71129.1 - 1.8e-20 73.2 43.4 3.4e-20 72.3 43.4 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily GCP_C_terminal PF04130.13 CCC71130.1 - 1.4e-32 113.4 5.0 3.2e-32 112.2 5.0 1.5 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 CCC71130.1 - 2.3e-28 99.7 5.1 5.9e-28 98.4 5.1 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal DUF1160 PF06648.11 CCC71130.1 - 0.036 14.0 1.9 0.23 11.5 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1160) Tub PF01167.18 CCC71130.1 - 0.039 13.7 0.0 6.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Tub family DUF5390 PF17365.2 CCC71130.1 - 1.8 8.8 6.3 5.8 7.2 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5390) Gar1 PF04410.14 CCC71131.1 - 2.1e-45 154.3 0.8 2.1e-45 154.3 0.8 2.6 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region PIGA PF08288.12 CCC71131.1 - 0.047 14.3 0.0 0.076 13.6 0.0 1.3 1 0 0 1 1 1 0 PIGA (GPI anchor biosynthesis) Cyclin_N PF00134.23 CCC71132.1 - 6.8e-15 54.9 0.8 1.6e-14 53.8 0.3 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 CCC71132.1 - 1.2e-07 32.1 0.1 2.7e-07 30.9 0.1 1.7 1 1 0 1 1 1 1 Cyclin C-terminal domain PDZ_1 PF12812.7 CCC71133.1 - 9e-52 173.0 0.1 4.2e-37 126.0 0.0 3.1 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 CCC71133.1 - 4.3e-22 79.6 0.1 1.7e-20 74.4 0.0 2.4 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 CCC71133.1 - 9.1e-11 41.9 4.2 0.002 18.4 0.4 4.8 4 0 0 4 4 4 2 PDZ domain PDZ_6 PF17820.1 CCC71133.1 - 2.3e-10 40.2 0.8 0.00032 20.5 0.4 3.8 4 0 0 4 4 4 2 PDZ domain PDZ PF00595.24 CCC71133.1 - 3.3e-09 37.0 0.0 6.3e-05 23.3 0.0 3.2 3 0 0 3 3 3 2 PDZ domain Trypsin PF00089.26 CCC71133.1 - 0.00032 20.6 0.0 0.00085 19.2 0.0 1.7 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.6 CCC71133.1 - 0.0084 16.1 0.2 9 6.4 0.0 3.3 3 0 0 3 3 3 1 Tricorn protease PDZ domain DUF31 PF01732.16 CCC71133.1 - 0.016 14.8 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.21 CCC71133.1 - 0.15 11.9 0.1 0.37 10.6 0.1 1.6 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease ThiS PF02597.20 CCC71133.1 - 0.16 12.7 0.7 62 4.3 0.0 3.5 2 1 1 3 3 3 0 ThiS family Peptidase_S46 PF10459.9 CCC71133.1 - 0.22 10.1 0.1 0.5 8.9 0.0 1.5 2 0 0 2 2 2 0 Peptidase S46 Ribosomal_L35p PF01632.19 CCC71134.1 - 2e-11 44.2 5.3 2.7e-11 43.8 5.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 TPR_1 PF00515.28 CCC71135.1 - 1e-31 107.5 33.5 3.5e-07 29.8 0.6 10.1 9 2 1 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.17 CCC71135.1 - 3.5e-31 104.8 31.6 4.8e-06 26.3 0.5 10.8 11 1 0 11 11 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 CCC71135.1 - 1.7e-21 74.6 36.8 4.6e-05 23.3 0.3 9.6 11 0 0 11 11 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 CCC71135.1 - 2.8e-21 75.9 3.1 0.00065 20.3 0.0 6.1 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCC71135.1 - 1.2e-18 66.4 20.4 0.00019 21.0 0.1 6.9 5 2 1 6 6 6 5 TPR repeat TPR_12 PF13424.6 CCC71135.1 - 1.2e-17 63.9 17.0 0.0029 17.9 0.1 7.8 6 2 2 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 CCC71135.1 - 2.8e-17 63.0 15.3 6.4e-05 23.4 0.3 7.2 6 1 3 9 9 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 CCC71135.1 - 6.8e-16 57.6 12.1 0.0047 17.6 0.1 10.1 6 3 5 11 11 10 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCC71135.1 - 4.8e-13 48.5 13.5 0.0052 17.1 0.0 8.7 9 1 0 9 9 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCC71135.1 - 1.3e-10 40.5 16.4 0.59 10.3 0.4 8.7 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 CCC71135.1 - 1.6e-08 34.6 0.5 0.56 10.4 0.0 5.5 5 1 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC71135.1 - 4e-08 33.4 11.3 0.057 13.7 1.4 5.0 3 2 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_21 PF09976.9 CCC71135.1 - 1.7e-06 27.9 15.1 0.031 14.0 0.1 5.1 4 1 0 5 5 5 3 Tetratricopeptide repeat-like domain TPR_MalT PF17874.1 CCC71135.1 - 1.6e-05 24.5 0.1 0.0001 21.8 0.0 2.4 2 0 0 2 2 2 1 MalT-like TPR region HrpB1_HrpK PF09613.10 CCC71135.1 - 0.00078 19.1 0.0 1 9.0 0.2 2.8 1 1 1 2 2 2 2 Bacterial type III secretion protein (HrpB1_HrpK) Exonuc_VII_S PF02609.16 CCC71135.1 - 0.0013 18.8 5.1 0.059 13.4 0.4 3.6 3 0 0 3 3 3 1 Exonuclease VII small subunit DUF3808 PF10300.9 CCC71135.1 - 0.0018 17.1 11.5 0.0095 14.7 0.1 4.0 4 1 1 5 5 5 2 Protein of unknown function (DUF3808) TPR_6 PF13174.6 CCC71135.1 - 0.026 15.2 21.2 7.4 7.5 0.0 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF2681 PF10883.8 CCC71135.1 - 0.032 14.6 1.6 0.11 12.9 1.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Sel1 PF08238.12 CCC71135.1 - 0.06 14.0 2.9 5.8 7.7 0.0 4.3 4 0 0 4 4 4 0 Sel1 repeat TPR_3 PF07720.12 CCC71135.1 - 0.28 11.2 13.5 2.6 8.1 0.0 5.1 4 0 0 4 4 4 0 Tetratricopeptide repeat RPN7 PF10602.9 CCC71135.1 - 0.53 10.0 5.7 18 5.0 0.1 4.0 4 1 0 4 4 4 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.9 CCC71135.1 - 0.6 9.6 5.8 8.8 5.9 0.1 5.2 6 0 0 6 6 5 0 SHNi-TPR TPR_10 PF13374.6 CCC71135.1 - 2.1 8.4 19.9 0.63 10.0 0.1 7.0 10 0 0 10 10 10 0 Tetratricopeptide repeat Peptidase_S49_N PF08496.10 CCC71135.1 - 2.9 8.0 6.1 0.62 10.1 0.3 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal CTU2 PF10288.9 CCC71136.1 - 1.5e-21 76.7 0.7 4.6e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 Zn_Tnp_IS91 PF14319.6 CCC71136.1 - 0.0085 16.1 1.9 0.022 14.8 1.9 1.7 1 0 0 1 1 1 1 Transposase zinc-binding domain zf-A20 PF01754.16 CCC71136.1 - 0.36 10.8 3.7 0.25 11.3 0.2 2.5 2 0 0 2 2 2 0 A20-like zinc finger GLF PF03275.13 CCC71136.1 - 0.73 9.5 4.0 2.9 7.5 0.1 2.7 3 0 0 3 3 3 0 UDP-galactopyranose mutase DCP2 PF05026.13 CCC71137.1 - 2.1e-26 92.1 0.7 6e-26 90.6 0.7 1.9 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.28 CCC71137.1 - 5.5e-13 49.1 0.0 1.3e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain Orthopox_F6 PF06601.12 CCC71137.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.6 3 0 0 3 3 3 0 Orthopoxvirus F6 protein Malate_synthase PF01274.22 CCC71138.1 - 3.6e-220 731.7 0.0 4.3e-220 731.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 CCC71138.1 - 0.083 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family FHA PF00498.26 CCC71139.1 - 9.8e-15 54.7 0.1 2.3e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 FHA domain zf-RING_11 PF17123.5 CCC71139.1 - 1.9e-10 40.3 10.3 3.4e-10 39.5 10.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 CCC71139.1 - 1.2e-06 28.7 11.1 2e-06 28.0 11.1 1.3 1 0 0 1 1 1 1 Ring finger domain Yop-YscD_cpl PF16697.5 CCC71139.1 - 0.00045 20.5 0.0 0.0012 19.1 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-rbx1 PF12678.7 CCC71139.1 - 0.0005 20.3 7.2 0.0011 19.2 7.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 CCC71139.1 - 0.0013 18.7 3.8 0.0028 17.7 3.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 CCC71139.1 - 0.0022 17.9 8.0 0.0036 17.2 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CCC71139.1 - 0.0037 17.1 10.1 0.0066 16.3 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCC71139.1 - 0.026 14.4 10.1 0.045 13.6 10.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Sec_GG PF07549.14 CCC71139.1 - 0.048 13.2 0.1 0.17 11.4 0.2 2.0 2 0 0 2 2 2 0 SecD/SecF GG Motif zf-C3HC4_3 PF13920.6 CCC71139.1 - 0.14 12.1 10.5 0.22 11.4 10.5 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosomal_L31 PF01197.18 CCC71139.1 - 0.15 12.3 0.6 0.47 10.7 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein L31 zf-RING_UBOX PF13445.6 CCC71139.1 - 0.31 11.1 9.3 0.73 9.9 9.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger adh_short PF00106.25 CCC71140.1 - 6.8e-26 90.9 0.2 8.3e-26 90.6 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCC71140.1 - 9.1e-18 64.7 0.1 1.1e-17 64.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCC71140.1 - 0.00032 20.7 0.1 0.00043 20.3 0.1 1.2 1 0 0 1 1 1 1 KR domain PfaD_N PF18328.1 CCC71140.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Fatty acid synthase subunit PfaD N-terminal domain DUF2417 PF10329.9 CCC71141.1 - 1.5e-79 266.8 9.4 2.2e-79 266.2 9.4 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.7 CCC71141.1 - 0.0013 19.3 0.1 0.002 18.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2339 PF10101.9 CCC71141.1 - 0.13 10.8 3.5 0.19 10.3 3.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) DUF3246 PF11596.8 CCC71141.1 - 0.45 9.9 3.0 0.7 9.3 3.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) RNA_pol_L_2 PF13656.6 CCC71142.1 - 4.4e-33 112.9 0.0 6.7e-33 112.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 CCC71142.1 - 9.9e-15 53.7 0.0 1.4e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain NOA36 PF06524.12 CCC71142.1 - 4.6 6.5 9.3 16 4.7 9.5 1.6 2 0 0 2 2 2 0 NOA36 protein Sporozoite_P67 PF05642.11 CCC71142.1 - 9.3 4.2 7.5 11 4.0 7.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DEAD PF00270.29 CCC71143.1 - 2.3e-48 164.3 0.0 9.7e-48 162.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC71143.1 - 3.8e-33 114.1 0.0 2.3e-32 111.6 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC71143.1 - 0.00019 21.5 0.0 0.00052 20.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 CCC71143.1 - 0.00034 19.5 0.0 0.0042 15.9 0.0 2.2 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 AAA_19 PF13245.6 CCC71143.1 - 0.016 15.5 0.0 1.9 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF5335 PF17269.2 CCC71143.1 - 0.038 13.8 0.1 0.079 12.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Cyt-b5 PF00173.28 CCC71144.1 - 4.7e-25 87.5 0.0 7.9e-25 86.8 0.0 1.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.22 CCC71145.1 - 9.5e-20 70.2 0.0 2e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCC71145.1 - 0.0055 16.3 0.0 0.0086 15.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 CCC71145.1 - 0.023 14.7 0.0 0.089 12.9 0.0 2.0 1 1 0 1 1 1 0 Limkain b1 RL PF17797.1 CCC71145.1 - 0.043 13.8 0.1 0.19 11.7 0.0 2.1 2 1 0 2 2 2 0 RL domain Nup35_RRM_2 PF14605.6 CCC71145.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif His_Phos_1 PF00300.22 CCC71146.1 - 6.7e-20 71.6 0.0 2.1e-19 70.0 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) EF-hand_like PF09279.11 CCC71146.1 - 0.18 12.3 0.0 0.35 11.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like Syja_N PF02383.18 CCC71147.1 - 4e-76 256.4 0.0 8e-76 255.4 0.0 1.5 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 CCC71147.1 - 1.2e-15 57.7 0.0 2.2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DNA_pol_B PF00136.21 CCC71149.1 - 2.2e-123 412.4 5.4 3.4e-123 411.8 5.4 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.10 CCC71149.1 - 1e-63 214.5 3.3 2.5e-63 213.2 3.3 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 CCC71149.1 - 2.4e-42 145.3 0.1 1.9e-41 142.3 0.0 2.4 3 0 0 3 3 3 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 CCC71149.1 - 8.2e-21 73.9 9.9 8.2e-21 73.9 9.9 2.3 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal Aa_trans PF01490.18 CCC71150.1 - 4.4e-94 315.5 32.7 5.4e-94 315.2 32.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF202 PF02656.15 CCC71150.1 - 0.5 10.8 6.3 0.34 11.4 0.1 3.6 3 2 0 3 3 3 0 Domain of unknown function (DUF202) DUF4094 PF13334.6 CCC71151.1 - 0.11 12.9 0.0 12 6.4 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Y_phosphatase2 PF03162.13 CCC71152.1 - 4.1e-57 192.4 0.0 5.8e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCC71152.1 - 3.4e-05 23.9 0.0 0.00014 21.9 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family Vps39_2 PF10367.9 CCC71152.1 - 0.022 15.2 0.2 0.036 14.5 0.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DSPc PF00782.20 CCC71152.1 - 0.045 13.6 0.0 0.083 12.7 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCC71152.1 - 0.16 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DAD PF02109.16 CCC71153.1 - 1.6e-38 131.4 6.3 2.1e-38 131.0 6.3 1.2 1 0 0 1 1 1 1 DAD family PalH PF08733.10 CCC71153.1 - 0.0052 15.8 2.8 0.0055 15.8 2.8 1.1 1 0 0 1 1 1 1 PalH/RIM21 DUF2207 PF09972.9 CCC71153.1 - 0.028 13.2 0.3 0.032 13.0 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ING PF12998.7 CCC71154.1 - 5.8e-21 75.0 0.8 5.8e-21 75.0 0.8 1.7 2 1 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CCC71154.1 - 1.1e-05 25.2 8.0 1.9e-05 24.5 8.0 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CCC71154.1 - 0.003 17.1 2.1 0.0072 15.9 2.1 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CCC71154.1 - 0.027 14.7 1.5 0.058 13.7 1.5 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Ribosomal_S7e PF01251.18 CCC71155.1 - 8.6e-22 77.8 0.1 9.3e-22 77.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Mem_trans PF03547.18 CCC71156.1 - 4.6e-29 101.0 1.8 6.8e-29 100.4 1.8 1.3 1 0 0 1 1 1 1 Membrane transport protein Zip PF02535.22 CCC71156.1 - 6.1 6.0 6.0 18 4.4 6.0 2.0 1 1 0 1 1 1 0 ZIP Zinc transporter DUF2183 PF09949.9 CCC71157.1 - 8.9e-31 106.2 0.2 6.8e-30 103.3 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) DFRP_C PF16543.5 CCC71158.1 - 5.8e-25 87.6 7.1 5.8e-25 87.6 7.1 4.1 4 0 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 CCC71158.1 - 1.6e-05 25.5 15.6 0.00067 20.3 4.2 4.0 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 CCC71158.1 - 0.00025 20.9 0.2 0.00025 20.9 0.2 2.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCC71158.1 - 0.00046 20.1 14.4 0.00071 19.5 4.4 3.1 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH_4 PF18044.1 CCC71158.1 - 0.00047 19.9 7.2 0.015 15.1 1.0 3.3 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 CCC71158.1 - 0.0036 17.7 10.8 0.29 11.7 0.6 2.7 2 1 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 CCC71158.1 - 0.35 11.1 9.1 0.72 10.1 0.4 3.1 2 1 1 3 3 3 0 Zinc-finger containing family NST1 PF13945.6 CCC71159.1 - 7.7e-07 29.4 18.2 7.7e-07 29.4 18.2 6.8 5 2 1 6 6 6 1 Salt tolerance down-regulator Ras PF00071.22 CCC71160.1 - 6.5e-51 172.1 0.0 7.5e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC71160.1 - 4.6e-23 81.7 0.0 6.1e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC71160.1 - 7.2e-10 38.6 0.0 8.9e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 CCC71160.1 - 0.0012 18.6 0.0 0.71 9.6 0.0 2.2 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CCC71160.1 - 0.058 12.8 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.6 CCC71160.1 - 0.068 13.0 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DNA_topoisoIV PF00521.20 CCC71161.1 - 3.2e-125 418.4 0.0 3.2e-125 418.4 0.0 2.8 4 0 0 4 4 4 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 CCC71161.1 - 1.7e-49 167.4 1.1 1.7e-49 167.4 1.1 2.9 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 CCC71161.1 - 2.6e-25 88.9 3.8 6.7e-25 87.6 3.8 1.7 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 CCC71161.1 - 4e-14 53.1 0.1 3.2e-13 50.2 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 CCC71161.1 - 7.2e-07 29.4 0.0 2.9e-06 27.5 0.0 2.1 1 0 0 1 1 1 1 Toprim domain Bin3 PF06859.12 CCC71161.1 - 0.19 12.4 1.5 0.8 10.4 0.1 2.9 2 0 0 2 2 2 0 Bicoid-interacting protein 3 (Bin3) SNN_linker PF09050.10 CCC71161.1 - 0.44 10.4 2.0 3.8 7.4 0.3 2.8 2 0 0 2 2 2 0 Stannin unstructured linker Uds1 PF15456.6 CCC71161.1 - 0.72 10.0 6.4 0.72 10.0 0.7 2.9 1 1 1 2 2 2 0 Up-regulated During Septation C2 PF00168.30 CCC71162.1 - 3.4e-52 175.0 4.6 4.5e-20 71.9 0.1 4.7 4 0 0 4 4 4 4 C2 domain Na_trans_assoc PF06512.13 CCC71162.1 - 0.028 14.7 0.0 0.067 13.5 0.0 1.6 1 0 0 1 1 1 0 Sodium ion transport-associated DUF4522 PF15022.6 CCC71162.1 - 0.24 11.7 1.2 0.69 10.2 1.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) DUF347 PF03988.12 CCC71162.1 - 0.36 11.1 1.1 4.7 7.5 0.0 2.5 2 0 0 2 2 2 0 Repeat of Unknown Function (DUF347) Sec20 PF03908.13 CCC71162.1 - 0.47 10.4 3.9 7.3 6.6 2.1 2.8 2 0 0 2 2 2 0 Sec20 Snapin_Pallidin PF14712.6 CCC71163.1 - 0.00025 21.4 6.0 0.00048 20.5 6.0 1.4 1 1 0 1 1 1 1 Snapin/Pallidin LOH1CR12 PF10158.9 CCC71163.1 - 0.0027 17.7 0.4 0.0031 17.5 0.4 1.2 1 0 0 1 1 1 1 Tumour suppressor protein YscO PF07321.12 CCC71163.1 - 0.0055 16.7 0.4 0.0069 16.4 0.4 1.2 1 0 0 1 1 1 1 Type III secretion protein YscO Fib_alpha PF08702.10 CCC71163.1 - 0.13 12.5 1.4 0.15 12.2 1.4 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family EMP24_GP25L PF01105.24 CCC71163.1 - 0.89 9.5 4.2 3.2 7.7 0.3 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Mito_carr PF00153.27 CCC71164.1 - 1.5e-62 207.5 4.3 1.5e-20 72.9 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.32 CCC71164.1 - 1.1e-12 46.6 6.3 0.0021 17.5 0.2 5.0 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 CCC71164.1 - 1.2e-12 48.1 5.9 9.6e-09 35.6 1.9 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCC71164.1 - 1.5e-12 46.3 5.0 0.00098 18.9 0.4 4.5 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 CCC71164.1 - 7.1e-09 34.8 8.9 0.017 14.6 0.2 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 CCC71164.1 - 5.8e-07 29.3 6.8 2.6e-05 24.0 2.4 3.5 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.6 CCC71164.1 - 0.00044 20.5 0.1 0.22 11.9 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CCC71164.1 - 0.028 14.8 1.6 0.11 12.8 0.1 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 CCC71164.1 - 0.87 9.8 5.4 38 4.6 5.4 2.7 1 1 1 2 2 2 0 Dockerin type I domain DNA_mis_repair PF01119.19 CCC71165.1 - 9.8e-26 89.8 0.3 2.7e-25 88.4 0.1 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.11 CCC71165.1 - 1.6e-23 83.1 0.0 3.2e-23 82.1 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 CCC71165.1 - 5.6e-10 39.2 0.0 1.6e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 CCC71165.1 - 1.3e-05 25.6 0.0 3.9e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Flocculin PF00624.18 CCC71167.1 - 3.7e-10 39.9 8.6 3.7e-10 39.9 8.6 10.0 9 1 0 9 9 9 1 Flocculin repeat Ribosomal_S13 PF00416.22 CCC71168.1 - 4.7e-20 72.3 0.5 7.4e-18 65.2 0.5 2.1 1 1 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CCC71168.1 - 0.0028 16.5 0.0 0.0031 16.3 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.8 CCC71168.1 - 0.0093 16.2 0.0 0.027 14.8 0.0 1.8 2 0 0 2 2 2 1 IMS family HHH motif EOS1 PF12326.8 CCC71169.1 - 3.9e-61 206.0 9.0 3.9e-61 206.0 9.0 1.8 2 0 0 2 2 2 1 N-glycosylation protein YukC PF10140.9 CCC71169.1 - 0.087 11.6 0.0 0.087 11.6 0.0 1.9 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukC IMUP PF15761.5 CCC71169.1 - 0.34 11.6 4.8 0.68 10.6 4.8 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein SR-25 PF10500.9 CCC71169.1 - 0.5 9.9 9.9 0.84 9.2 9.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MarC PF01914.17 CCC71169.1 - 2.4 7.5 9.3 0.47 9.8 5.4 1.9 2 0 0 2 2 2 0 MarC family integral membrane protein Tropomyosin_1 PF12718.7 CCC71170.1 - 7.2e-49 165.6 55.9 2.5e-33 115.2 37.3 2.1 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.20 CCC71170.1 - 3e-09 36.6 48.6 3.1e-05 23.5 21.0 2.1 1 1 1 2 2 2 2 Tropomyosin DUF3450 PF11932.8 CCC71170.1 - 1.6e-08 34.2 41.2 0.00056 19.3 7.4 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3450) KLRAQ PF10205.9 CCC71170.1 - 3.6e-07 30.4 38.7 0.0016 18.7 8.9 4.0 1 1 3 4 4 4 2 Predicted coiled-coil domain-containing protein ADIP PF11559.8 CCC71170.1 - 4.1e-06 26.9 42.8 0.00036 20.7 12.8 3.1 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding GAS PF13851.6 CCC71170.1 - 2.4e-05 23.8 49.7 0.05 12.9 19.1 3.0 1 1 2 3 3 3 3 Growth-arrest specific micro-tubule binding Filament PF00038.21 CCC71170.1 - 3.5e-05 23.5 44.4 6.1e-05 22.8 44.4 1.5 1 1 0 1 1 1 1 Intermediate filament protein TMF_DNA_bd PF12329.8 CCC71170.1 - 9.9e-05 22.3 62.5 0.01 15.8 14.4 4.1 1 1 3 4 4 4 2 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 CCC71170.1 - 0.00011 22.5 46.3 0.022 15.0 17.5 3.2 1 1 2 3 3 3 2 Autophagy protein 16 (ATG16) bZIP_1 PF00170.21 CCC71170.1 - 0.00012 22.1 49.8 0.058 13.5 7.3 5.7 2 1 4 6 6 6 3 bZIP transcription factor DUF1664 PF07889.12 CCC71170.1 - 0.00089 19.3 27.6 0.0089 16.1 11.0 3.3 1 1 2 3 3 3 1 Protein of unknown function (DUF1664) Taxilin PF09728.9 CCC71170.1 - 0.00094 18.4 8.8 0.00094 18.4 8.8 2.5 2 1 0 2 2 2 1 Myosin-like coiled-coil protein DUF3584 PF12128.8 CCC71170.1 - 0.002 15.7 38.5 0.0024 15.5 38.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) WXG100 PF06013.12 CCC71170.1 - 0.0022 18.2 19.6 0.51 10.6 0.3 4.7 2 1 2 4 4 4 1 Proteins of 100 residues with WXG Spc7 PF08317.11 CCC71170.1 - 0.0027 16.6 50.6 0.016 14.1 31.9 2.2 1 1 1 2 2 2 2 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 CCC71170.1 - 0.0035 17.9 22.0 0.0035 17.9 22.0 3.4 1 1 3 4 4 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 ALIX_LYPXL_bnd PF13949.6 CCC71170.1 - 0.0036 16.7 31.8 0.0045 16.3 31.8 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV ERM PF00769.19 CCC71170.1 - 0.0038 17.1 51.4 0.2 11.4 13.2 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family EzrA PF06160.12 CCC71170.1 - 0.0039 15.4 44.6 0.074 11.2 33.4 2.1 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA Ax_dynein_light PF10211.9 CCC71170.1 - 0.0045 16.9 50.4 0.24 11.3 9.8 3.8 2 1 2 4 4 4 1 Axonemal dynein light chain NPV_P10 PF05531.12 CCC71170.1 - 0.0054 17.2 25.9 1.9 9.0 0.0 4.7 1 1 3 4 4 4 1 Nucleopolyhedrovirus P10 protein DUF4164 PF13747.6 CCC71170.1 - 0.0091 16.3 8.1 0.0091 16.3 8.1 3.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.12 CCC71170.1 - 0.0096 16.0 53.0 2.2 8.4 11.8 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 CCC71170.1 - 0.018 14.9 15.5 0.018 14.9 15.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) CENP-F_leu_zip PF10473.9 CCC71170.1 - 0.019 15.0 55.1 0.31 11.1 32.4 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 CCC71170.1 - 0.02 15.0 5.0 0.02 15.0 5.0 6.1 3 2 2 5 5 4 0 Basic region leucine zipper Jnk-SapK_ap_N PF09744.9 CCC71170.1 - 0.025 14.8 51.1 0.24 11.6 30.9 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF2408 PF10303.9 CCC71170.1 - 0.035 14.7 1.9 0.035 14.7 1.9 4.2 1 1 1 2 2 1 0 Protein of unknown function (DUF2408) HemX PF04375.14 CCC71170.1 - 0.036 13.3 34.1 0.12 11.6 6.8 3.0 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase FlaC_arch PF05377.11 CCC71170.1 - 0.037 14.4 44.4 0.59 10.6 3.3 5.9 1 1 5 6 6 6 0 Flagella accessory protein C (FlaC) MbeD_MobD PF04899.12 CCC71170.1 - 0.037 14.1 0.8 0.037 14.1 0.8 4.0 3 1 1 4 4 4 0 MbeD/MobD like Prefoldin_2 PF01920.20 CCC71170.1 - 0.039 13.9 57.5 0.17 11.8 8.6 5.2 2 2 3 5 5 5 0 Prefoldin subunit Laminin_II PF06009.12 CCC71170.1 - 0.048 13.7 34.2 1.2 9.2 12.2 3.4 1 1 2 3 3 3 0 Laminin Domain II KASH_CCD PF14662.6 CCC71170.1 - 0.056 13.3 52.3 0.18 11.6 32.9 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH DUF4600 PF15372.6 CCC71170.1 - 0.06 13.8 41.9 0.84 10.1 19.4 3.8 2 1 1 3 3 2 0 Domain of unknown function (DUF4600) BLOC1_2 PF10046.9 CCC71170.1 - 0.072 13.4 40.6 2 8.8 11.5 4.2 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 CCC71170.1 - 0.076 13.5 62.5 0.29 11.7 28.6 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region FPP PF05911.11 CCC71170.1 - 0.077 11.2 48.4 0.17 10.0 23.6 2.1 1 1 1 2 2 2 0 Filament-like plant protein, long coiled-coil DHR10 PF18595.1 CCC71170.1 - 0.085 12.9 52.7 0.54 10.3 11.9 3.5 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain MscS_porin PF12795.7 CCC71170.1 - 0.095 12.2 43.6 0.1 12.1 26.3 2.3 1 1 0 2 2 2 0 Mechanosensitive ion channel porin domain HMMR_N PF15905.5 CCC71170.1 - 0.096 12.1 52.8 0.28 10.6 34.0 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Uso1_p115_C PF04871.13 CCC71170.1 - 0.099 13.0 52.1 0.78 10.1 18.6 3.1 1 1 3 4 4 4 0 Uso1 / p115 like vesicle tethering protein, C terminal region Atg14 PF10186.9 CCC71170.1 - 0.18 10.9 37.7 0.16 11.0 22.0 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lebercilin PF15619.6 CCC71170.1 - 0.2 11.3 48.2 0.2 11.3 22.6 2.8 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4201 PF13870.6 CCC71170.1 - 0.2 11.4 44.7 2.3 7.9 32.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Fib_alpha PF08702.10 CCC71170.1 - 0.24 11.6 33.7 0.57 10.4 15.9 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family YkyA PF10368.9 CCC71170.1 - 0.29 10.8 48.6 0.31 10.7 29.9 2.3 1 1 1 2 2 2 0 Putative cell-wall binding lipoprotein T3SSipB PF16535.5 CCC71170.1 - 0.35 11.3 27.4 1 9.8 15.0 2.8 1 1 1 2 2 2 0 Type III cell invasion protein SipB HOOK PF05622.12 CCC71170.1 - 0.36 8.9 47.4 0.71 8.0 47.4 1.4 1 1 0 1 1 1 0 HOOK protein OmpH PF03938.14 CCC71170.1 - 0.37 11.1 43.3 1.1 9.6 20.5 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Dynamitin PF04912.14 CCC71170.1 - 0.4 10.0 39.0 1.5 8.1 22.7 2.2 1 1 1 2 2 2 0 Dynamitin ZapB PF06005.12 CCC71170.1 - 0.45 11.0 58.2 3.4 8.2 12.6 5.0 1 1 4 5 5 4 0 Cell division protein ZapB IFT57 PF10498.9 CCC71170.1 - 0.47 9.4 39.6 1.9 7.4 39.6 1.9 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF3287 PF11690.8 CCC71170.1 - 0.59 9.9 12.2 0.33 10.7 2.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3287) DUF4200 PF13863.6 CCC71170.1 - 0.66 10.4 52.6 1.6 9.1 4.7 4.0 1 1 3 4 4 4 0 Domain of unknown function (DUF4200) Cnn_1N PF07989.11 CCC71170.1 - 0.77 10.0 48.3 1.5 9.0 4.4 4.9 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 LPP PF04728.13 CCC71170.1 - 0.87 10.0 24.5 0.83 10.1 0.9 5.0 1 1 3 5 5 5 0 Lipoprotein leucine-zipper UPF0242 PF06785.11 CCC71170.1 - 0.89 9.6 52.5 11 6.1 21.1 2.9 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Sec34 PF04136.15 CCC71170.1 - 0.99 9.3 32.6 3.2 7.6 8.6 3.1 1 1 2 3 3 3 0 Sec34-like family CALCOCO1 PF07888.11 CCC71170.1 - 1 8.1 44.9 0.42 9.4 36.6 2.0 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF5082 PF16888.5 CCC71170.1 - 1.3 9.4 38.8 2.4 8.4 14.0 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Mod_r PF07200.13 CCC71170.1 - 1.4 9.0 47.7 3.5 7.7 24.0 3.8 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein YabA PF06156.13 CCC71170.1 - 1.4 9.6 40.5 8.6 7.1 18.3 3.5 1 1 2 3 3 3 0 Initiation control protein YabA Snapin_Pallidin PF14712.6 CCC71170.1 - 1.4 9.4 35.8 0.074 13.5 13.1 4.3 1 1 4 5 5 5 0 Snapin/Pallidin Occludin_ELL PF07303.13 CCC71170.1 - 1.6 9.5 30.3 4.6 8.0 5.8 4.0 1 1 3 4 4 3 0 Occludin homology domain DUF4795 PF16043.5 CCC71170.1 - 1.6 8.3 43.3 0.74 9.4 13.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) ACP_PD PF04336.12 CCC71170.1 - 2 8.9 8.4 0.94 9.9 0.4 3.1 2 1 0 2 2 2 0 Acyl carrier protein phosphodiesterase SHE3 PF17078.5 CCC71170.1 - 2.2 8.0 43.6 3.8 7.1 10.1 2.6 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 Fez1 PF06818.15 CCC71170.1 - 2.4 8.6 42.1 3.6 8.0 22.2 2.1 1 1 1 2 2 2 0 Fez1 CEP209_CC5 PF16574.5 CCC71170.1 - 2.5 8.3 45.5 0.54 10.4 8.8 4.1 1 1 3 4 4 4 0 Coiled-coil region of centrosome protein CE290 STAT_alpha PF01017.20 CCC71170.1 - 2.6 7.9 34.9 7.4 6.4 5.9 3.1 2 1 0 2 2 2 0 STAT protein, all-alpha domain Lectin_N PF03954.14 CCC71170.1 - 2.8 7.7 24.5 1.1 9.1 8.1 3.7 1 1 3 5 5 4 0 Hepatic lectin, N-terminal domain HMMR_C PF15908.5 CCC71170.1 - 3 8.1 36.0 2.8 8.2 4.6 2.6 1 1 2 3 3 3 0 Hyaluronan mediated motility receptor C-terminal DASH_Dam1 PF08653.10 CCC71170.1 - 3.3 7.6 21.2 2.5 8.0 2.8 4.9 4 1 2 6 6 5 0 DASH complex subunit Dam1 AAA_13 PF13166.6 CCC71170.1 - 3.3 6.2 39.8 6.2 5.3 39.8 1.4 1 1 0 1 1 1 0 AAA domain DUF745 PF05335.13 CCC71170.1 - 3.7 7.2 29.7 4.8 6.9 5.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) PspA_IM30 PF04012.12 CCC71170.1 - 3.9 7.0 38.8 2.6 7.6 18.2 2.7 1 1 1 2 2 2 0 PspA/IM30 family Exonuc_VII_L PF02601.15 CCC71170.1 - 4 6.9 31.1 12 5.3 18.5 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit CLZ PF16526.5 CCC71170.1 - 4.3 7.8 42.8 2 8.8 5.9 5.0 1 1 2 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc24 PF08286.11 CCC71170.1 - 4.4 7.6 50.3 3.1 8.1 9.1 5.0 1 1 3 4 4 3 0 Spc24 subunit of Ndc80 MCPsignal PF00015.21 CCC71170.1 - 4.8 7.0 15.0 0.29 10.9 3.2 2.5 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DivIC PF04977.15 CCC71170.1 - 4.8 7.0 53.1 0.28 11.0 7.1 5.3 2 2 3 5 5 4 0 Septum formation initiator FTA4 PF13093.6 CCC71170.1 - 5.3 6.9 35.0 0.052 13.4 5.6 2.5 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 TMPIT PF07851.13 CCC71170.1 - 5.4 6.2 35.0 3.4 6.8 15.7 2.4 1 1 1 2 2 2 0 TMPIT-like protein FH2 PF02181.23 CCC71170.1 - 5.9 5.9 31.9 3.8 6.5 10.4 2.7 1 1 2 3 3 3 0 Formin Homology 2 Domain APG17 PF04108.12 CCC71170.1 - 6.7 5.7 32.5 4.5 6.3 6.7 2.7 1 1 1 2 2 2 0 Autophagy protein Apg17 Golgin_A5 PF09787.9 CCC71170.1 - 7.5 5.9 44.7 2.5 7.5 19.4 2.1 1 1 1 2 2 2 0 Golgin subfamily A member 5 Seryl_tRNA_N PF02403.22 CCC71170.1 - 9.7 6.5 45.6 0.22 11.8 15.5 3.6 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain DnaJ_C PF01556.18 CCC71172.1 - 1.9e-25 89.7 0.1 4.5e-25 88.5 0.0 1.6 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.31 CCC71172.1 - 2.2e-22 79.0 3.0 4.5e-22 77.9 3.0 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCC71172.1 - 2.9e-12 46.8 15.4 6.9e-12 45.6 15.4 1.7 1 0 0 1 1 1 1 DnaJ central domain TackOD1 PF18551.1 CCC71172.1 - 0.0061 16.3 4.2 1.3 8.6 0.2 2.6 2 0 0 2 2 2 2 Thaumarchaeal output domain 1 Gag_p17 PF00540.18 CCC71172.1 - 0.052 13.5 0.1 0.1 12.6 0.1 1.4 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) DUF1752 PF08550.10 CCC71173.1 - 1.7e-08 34.1 0.4 1.7e-08 34.1 0.4 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) SUIM_assoc PF16619.5 CCC71173.1 - 4.5 7.4 24.1 0.084 13.0 2.1 4.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Brix PF04427.18 CCC71174.1 - 8.6e-31 107.5 0.1 1.1e-30 107.2 0.1 1.2 1 0 0 1 1 1 1 Brix domain RNase_HII PF01351.18 CCC71176.1 - 3.8e-63 212.9 0.0 4.6e-63 212.7 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII 2-oxoacid_dh PF00198.23 CCC71177.1 - 5.2e-75 251.9 0.2 8.1e-75 251.2 0.2 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 CCC71177.1 - 3.1e-17 62.1 0.2 1.2e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.17 CCC71177.1 - 3.7e-14 52.8 0.3 9.4e-14 51.5 0.3 1.8 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.8 CCC71177.1 - 0.24 11.9 0.8 0.88 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) Tom7 PF08038.12 CCC71178.1 - 2.3e-19 68.7 0.1 3e-19 68.4 0.1 1.2 1 0 0 1 1 1 1 TOM7 family Ribosomal_L13 PF00572.18 CCC71179.1 - 2.6e-11 43.8 0.8 1.7e-09 38.0 0.2 2.5 2 1 0 2 2 2 1 Ribosomal protein L13 Forkhead PF00250.18 CCC71180.1 - 1e-33 115.4 0.2 4.7e-33 113.3 0.2 2.2 1 0 0 1 1 1 1 Forkhead domain FHA PF00498.26 CCC71180.1 - 5.6e-13 49.0 2.1 1.2e-12 48.0 0.1 2.7 3 0 0 3 3 3 1 FHA domain MMS19_C PF12460.8 CCC71181.1 - 1.5e-100 337.3 14.9 1.5e-100 337.3 14.9 2.1 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.6 CCC71181.1 - 4.9e-82 275.4 11.1 2.3e-79 266.7 1.4 4.9 5 1 0 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.22 CCC71181.1 - 0.0024 18.0 0.6 6.8 7.2 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 CCC71181.1 - 0.069 13.7 0.4 0.57 10.7 0.1 2.7 2 0 0 2 2 2 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 CCC71181.1 - 0.13 12.9 0.4 7.7 7.2 0.0 4.0 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.8 CCC71181.1 - 0.31 11.6 7.1 1.9 9.1 0.1 4.6 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation RTP1_C1 PF10363.9 CCC71181.1 - 1.3 9.2 4.6 2.5 8.3 0.2 3.3 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RRT14 PF17075.5 CCC71182.1 - 1.4e-57 195.1 31.8 1.6e-57 194.8 31.8 1.0 1 0 0 1 1 1 1 Regular of rDNA transcription protein 14 DUF960 PF06124.11 CCC71182.1 - 5.7 7.6 10.6 3.3 8.4 4.4 2.5 1 1 1 2 2 2 0 Staphylococcal protein of unknown function (DUF960) SLAC1 PF03595.17 CCC71183.1 - 2e-76 257.4 36.7 2.3e-76 257.1 36.7 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SUN PF03856.13 CCC71184.1 - 6.8e-98 327.0 12.6 1.2e-97 326.2 12.6 1.4 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Dehydrin PF00257.19 CCC71184.1 - 0.65 10.5 7.5 1.3 9.6 7.5 1.5 1 0 0 1 1 1 0 Dehydrin Mucin PF01456.17 CCC71184.1 - 0.98 9.4 25.4 1.8 8.5 25.4 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MFS_1 PF07690.16 CCC71186.1 - 2e-37 128.9 21.4 2e-37 128.9 21.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC71186.1 - 1.7e-16 60.1 4.8 1.7e-16 60.1 4.8 2.7 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_5 PF05631.14 CCC71186.1 - 0.00011 21.3 0.4 0.00021 20.4 0.4 1.4 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM TRI12 PF06609.13 CCC71186.1 - 0.00044 18.8 4.2 0.00068 18.2 4.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.9 CCC71186.1 - 0.093 13.0 0.3 7.6 6.8 0.0 2.4 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2304 PF10066.9 CCC71186.1 - 0.67 10.2 0.0 0.67 10.2 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2304) DUF2627 PF11118.8 CCC71186.1 - 8.3 7.1 7.7 10 6.8 1.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2627) DnaJ_C PF01556.18 CCC71187.1 - 7.9e-41 139.6 0.2 1e-40 139.2 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCC71187.1 - 7.1e-27 93.3 0.6 1.2e-26 92.6 0.6 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 CCC71187.1 - 1.2e-15 57.6 16.9 2.2e-15 56.8 16.9 1.5 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.19 CCC71187.1 - 0.27 11.2 11.1 2.3 8.3 1.9 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Anti-TRAP PF15777.5 CCC71187.1 - 2.8 8.0 16.0 5.3 7.1 1.9 3.3 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein MTS PF05175.14 CCC71188.1 - 2.2e-11 43.6 0.0 3.5e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 CCC71188.1 - 1.6e-08 34.5 0.0 2.3e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCC71188.1 - 3.5e-07 30.8 0.0 6.2e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 CCC71188.1 - 1.3e-05 25.0 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.15 CCC71188.1 - 6.6e-05 22.6 0.0 0.00011 21.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.16 CCC71188.1 - 0.00021 20.7 0.0 0.00025 20.4 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_11 PF08241.12 CCC71188.1 - 0.00097 19.7 0.0 0.0028 18.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CCC71188.1 - 0.0013 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 CCC71188.1 - 0.0024 17.9 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 CCC71188.1 - 0.0067 15.9 0.1 0.12 11.8 0.0 2.1 1 1 1 2 2 2 1 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 CCC71188.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 CCC71188.1 - 0.018 15.8 0.0 0.03 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 CCC71188.1 - 0.17 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Gcd10p PF04189.13 CCC71189.1 - 5.5e-101 337.6 0.7 8.7e-101 337.0 0.7 1.3 1 0 0 1 1 1 1 Gcd10p family Mrr_N PF14338.6 CCC71189.1 - 0.16 12.1 1.4 0.7 10.1 0.1 2.3 2 0 0 2 2 2 0 Mrr N-terminal domain Methyltr_RsmB-F PF01189.17 CCC71190.1 - 1.5e-82 276.1 0.0 2.8e-82 275.2 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 CCC71190.1 - 8.7e-08 32.6 0.0 3.7e-07 30.5 0.0 2.1 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 CCC71190.1 - 0.012 15.7 0.0 0.033 14.3 0.0 1.7 1 0 0 1 1 1 0 FtsJ-like methyltransferase Aldo_ket_red PF00248.21 CCC71191.1 - 6.3e-51 173.3 0.0 8.3e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Actin PF00022.19 CCC71192.1 - 3.3e-44 151.1 0.0 5.4e-40 137.3 0.0 2.8 1 1 0 1 1 1 1 Actin Caldesmon PF02029.15 CCC71192.1 - 6.3 5.4 41.7 9.6 4.8 41.7 1.2 1 0 0 1 1 1 0 Caldesmon Y_phosphatase2 PF03162.13 CCC71194.1 - 1.2e-53 181.1 0.0 1.4e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCC71194.1 - 1e-05 25.7 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Vac7 PF12751.7 CCC71195.1 - 6.9e-30 104.7 18.1 4.7e-24 85.5 0.3 4.5 1 1 3 4 4 4 2 Vacuolar segregation subunit 7 DUF2660 PF10859.8 CCC71195.1 - 0.065 13.7 0.2 0.38 11.2 0.2 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF4668 PF15701.5 CCC71195.1 - 0.093 12.6 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) DSPc PF00782.20 CCC71196.1 - 1.8e-37 128.1 0.0 3.8e-37 127.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCC71196.1 - 0.0015 18.1 0.0 0.0043 16.6 0.0 1.7 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 CCC71196.1 - 0.007 16.5 0.0 0.023 14.8 0.0 1.9 2 0 0 2 2 2 1 Inositol hexakisphosphate DSPn PF14671.6 CCC71196.1 - 0.023 15.1 0.1 0.054 13.9 0.1 1.5 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half Init_tRNA_PT PF04179.12 CCC71196.1 - 0.024 14.9 0.0 1 9.7 0.0 2.5 2 0 0 2 2 2 0 Rit1 DUSP-like domain COG5 PF10392.9 CCC71197.1 - 8.5e-41 139.2 1.5 8.5e-41 139.2 1.5 3.1 1 1 2 4 4 4 1 Golgi transport complex subunit 5 Casein PF00363.18 CCC71197.1 - 0.53 10.7 4.2 57 4.2 0.2 3.4 3 0 0 3 3 3 0 Casein PdaC PF13739.6 CCC71197.1 - 2.4 9.2 10.5 1.6 9.8 0.4 3.2 3 1 0 3 3 3 0 Deacetylase PdaC DUF2011 PF09428.10 CCC71198.1 - 3.1e-22 78.6 0.0 6.1e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Peptidase_C6 PF00851.18 CCC71198.1 - 0.027 13.4 1.2 0.036 13.0 1.2 1.1 1 0 0 1 1 1 0 Helper component proteinase TetR_C_19 PF17924.1 CCC71198.1 - 0.05 14.2 2.7 0.063 13.9 0.1 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Dynein_light PF01221.18 CCC71198.1 - 0.62 10.4 5.8 0.1 12.9 1.8 1.8 2 0 0 2 2 2 0 Dynein light chain type 1 Sec23_trunk PF04811.15 CCC71199.1 - 4.7e-66 222.8 0.3 9.7e-66 221.8 0.0 1.7 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CCC71199.1 - 2.7e-22 78.5 0.1 7.5e-22 77.1 0.1 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 CCC71199.1 - 4.4e-15 55.4 6.8 8.7e-15 54.5 6.8 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 CCC71199.1 - 8.7e-15 55.2 0.2 2.7e-14 53.7 0.2 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 CCC71199.1 - 4.8e-12 45.6 0.5 1e-11 44.5 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 CCC71199.1 - 0.029 13.8 0.2 0.081 12.3 0.2 1.7 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain zf-RanBP PF00641.18 CCC71199.1 - 0.11 11.8 0.5 0.22 10.9 0.5 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others UQ_con PF00179.26 CCC71200.1 - 2e-39 134.4 0.1 2.8e-39 134.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Alpha-amylase_C PF02806.18 CCC71201.1 - 4.3e-28 97.6 0.1 1.5e-27 95.9 0.1 2.0 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 CCC71201.1 - 3.3e-17 62.6 0.1 8.3e-17 61.3 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 CCC71201.1 - 1.5e-14 54.3 3.6 8.3e-14 51.9 0.1 2.8 3 1 1 4 4 4 1 Alpha amylase, catalytic domain Glyco_hydro_66 PF13199.6 CCC71201.1 - 0.01 14.5 0.0 0.02 13.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 66 Swm2 PF17083.5 CCC71202.1 - 2.1e-49 166.8 1.2 2.4e-49 166.6 1.2 1.0 1 0 0 1 1 1 1 Nucleolar protein Swm2 DUF2373 PF10180.9 CCC71203.1 - 1.9e-27 94.9 1.0 3.4e-27 94.1 1.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DDE_Tnp_1_assoc PF13808.6 CCC71203.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 DDE_Tnp_1-associated R3H-assoc PF13902.6 CCC71203.1 - 0.4 11.1 9.1 0.04 14.3 2.1 2.2 2 0 0 2 2 2 0 R3H-associated N-terminal domain HAD PF12710.7 CCC71204.1 - 2.7e-08 34.5 0.0 8.3e-07 29.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGK PF00162.19 CCC71205.1 - 1.8e-149 497.8 0.1 2.1e-149 497.6 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.11 CCC71205.1 - 0.0057 16.3 0.3 1.4 8.5 0.0 2.5 2 1 0 2 2 2 2 Propionate catabolism activator Peptidase_S51 PF03575.17 CCC71205.1 - 0.083 12.5 0.4 1.1 8.9 0.1 2.2 2 0 0 2 2 2 0 Peptidase family S51 Gpr1_Fun34_YaaH PF01184.19 CCC71206.1 - 1.2e-92 309.3 18.8 1.4e-92 309.0 18.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Rad9 PF04139.13 CCC71207.1 - 7.1e-11 42.0 1.6 0.00013 21.5 0.2 2.2 2 0 0 2 2 2 2 Rad9 PRA1 PF03208.19 CCC71208.1 - 2e-38 131.3 1.0 2.5e-38 130.9 1.0 1.1 1 0 0 1 1 1 1 PRA1 family protein DUF2207 PF09972.9 CCC71208.1 - 0.16 10.7 0.9 0.19 10.4 0.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2244 PF10003.9 CCC71208.1 - 1.4 8.6 5.3 0.81 9.4 0.3 2.1 1 1 1 2 2 2 0 Integral membrane protein (DUF2244) Peptidase_M1 PF01433.20 CCC71209.1 - 9.4e-48 162.6 0.5 1.4e-47 162.1 0.5 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 CCC71209.1 - 1.5e-34 118.5 0.4 4.6e-34 116.9 0.0 2.1 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 CCC71209.1 - 3e-31 109.1 0.9 4.9e-31 108.4 0.9 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M64 PF09471.10 CCC71209.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 IgA Peptidase M64 Peptidase_M61 PF05299.12 CCC71209.1 - 0.66 10.4 2.3 16 5.9 2.3 2.7 1 1 0 1 1 1 0 M61 glycyl aminopeptidase ALG11_N PF15924.5 CCC71211.1 - 6.1e-80 268.2 2.6 1e-79 267.5 2.6 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 CCC71211.1 - 8e-15 54.8 0.0 1.4e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCC71211.1 - 0.00024 21.5 0.0 0.00041 20.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Arm PF00514.23 CCC71212.1 - 1.6e-66 218.5 34.6 1.3e-11 44.1 0.0 11.2 12 0 0 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 CCC71212.1 - 2.6e-21 75.7 12.9 0.00061 20.2 0.1 8.4 7 1 1 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 CCC71212.1 - 2.8e-17 62.9 6.1 0.00025 21.4 0.0 7.6 3 3 4 8 8 8 4 HEAT repeats KAP PF05804.12 CCC71212.1 - 1.5e-11 43.2 3.7 7.9e-06 24.3 0.4 3.0 1 1 2 3 3 3 2 Kinesin-associated protein (KAP) Adaptin_N PF01602.20 CCC71212.1 - 2.8e-11 42.7 13.6 1.8e-07 30.1 2.3 3.1 1 1 1 2 2 2 2 Adaptin N terminal region HEAT PF02985.22 CCC71212.1 - 8.3e-11 41.2 25.6 0.28 11.5 0.2 10.5 11 1 1 12 12 11 3 HEAT repeat Arm_2 PF04826.13 CCC71212.1 - 1.4e-09 37.8 11.8 1.1e-05 25.0 4.8 3.3 2 1 0 3 3 3 2 Armadillo-like V-ATPase_H_C PF11698.8 CCC71212.1 - 3.8e-05 23.8 7.4 0.91 9.7 0.1 5.6 1 1 5 7 7 7 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 CCC71212.1 - 4.8e-05 22.8 5.4 0.011 15.0 1.3 3.2 1 1 2 3 3 3 2 V-ATPase subunit H Cnd1 PF12717.7 CCC71212.1 - 0.00014 22.0 13.4 0.83 9.7 2.2 5.2 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 CCC71212.1 - 0.00015 22.3 1.3 1.4 9.6 0.0 3.9 3 1 0 3 3 2 2 Vacuolar 14 Fab1-binding region DUF3361 PF11841.8 CCC71212.1 - 0.0016 18.4 7.5 0.27 11.2 0.2 4.2 1 1 3 4 4 4 1 Domain of unknown function (DUF3361) Tti2 PF10521.9 CCC71212.1 - 0.0016 18.0 0.3 0.02 14.5 0.0 2.7 3 0 0 3 3 3 1 Tti2 family DUF5578 PF17741.1 CCC71212.1 - 0.16 11.4 6.0 1.6 8.1 0.1 3.8 2 1 2 4 4 4 0 Family of unknown function (DUF5578) OapA PF04225.12 CCC71212.1 - 0.17 12.0 0.8 6 7.0 0.3 2.6 1 1 1 2 2 2 0 Opacity-associated protein A LysM-like domain RasGEF_N_2 PF14663.6 CCC71212.1 - 0.4 11.1 5.9 32 5.0 0.0 4.5 4 1 1 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain UNC45-central PF11701.8 CCC71212.1 - 1.7 8.6 9.6 1.6 8.7 0.4 4.2 3 1 2 5 5 5 0 Myosin-binding striated muscle assembly central YjeF_N PF03853.15 CCC71213.1 - 1.4e-19 70.6 0.0 2.6e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.10 CCC71213.1 - 0.00056 20.8 10.9 0.00056 20.8 10.9 3.0 3 0 0 3 3 3 1 FDF domain DUF150_C PF17384.2 CCC71213.1 - 0.074 13.2 0.1 0.18 11.9 0.1 1.6 1 0 0 1 1 1 0 RimP C-terminal SH3 domain eRF1_2 PF03464.15 CCC71214.1 - 5.4e-28 98.0 0.1 1.3e-27 96.8 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CCC71214.1 - 1.1e-24 87.0 0.1 3.2e-24 85.6 0.1 1.8 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CCC71214.1 - 5.9e-22 78.1 0.2 9.8e-22 77.3 0.2 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family5 PF18846.1 CCC71214.1 - 0.0076 16.5 0.6 0.02 15.1 0.6 1.7 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 5 Hema_HEFG PF02710.14 CCC71214.1 - 0.15 12.3 1.1 0.67 10.2 0.1 2.1 1 1 1 2 2 2 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein Septin PF00735.18 CCC71215.1 - 1.5e-102 342.7 1.6 1.8e-102 342.4 1.6 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CCC71215.1 - 1.8e-10 40.9 0.2 3.8e-10 39.8 0.1 1.6 2 0 0 2 2 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 CCC71215.1 - 1.5e-07 31.5 0.7 8.4e-07 29.0 0.2 2.1 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 CCC71215.1 - 2.7e-07 30.3 0.7 3.1e-05 23.6 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 CCC71215.1 - 1.2e-05 24.8 0.3 2.2e-05 23.9 0.3 1.6 1 1 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CCC71215.1 - 3e-05 24.1 1.3 0.21 11.6 0.2 2.5 1 1 1 2 2 2 2 Dynamin family AAA_16 PF13191.6 CCC71215.1 - 0.00058 20.3 0.0 0.001 19.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 CCC71215.1 - 0.0015 18.8 0.1 0.0046 17.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.22 CCC71215.1 - 0.0026 17.0 0.2 0.0049 16.1 0.2 1.5 1 1 0 1 1 1 1 NB-ARC domain FtsK_SpoIIIE PF01580.18 CCC71215.1 - 0.0039 16.6 0.0 0.0083 15.5 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family IIGP PF05049.13 CCC71215.1 - 0.014 14.5 0.6 0.042 12.9 0.2 1.9 1 1 1 2 2 2 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.27 CCC71215.1 - 0.015 15.8 2.4 0.029 14.9 2.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 CCC71215.1 - 0.016 15.2 0.3 0.057 13.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 CCC71215.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CCC71215.1 - 0.023 14.2 0.1 0.055 13.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 CCC71215.1 - 0.03 14.5 0.2 0.13 12.4 0.3 2.1 2 1 0 2 2 2 0 AAA domain Roc PF08477.13 CCC71215.1 - 0.038 14.2 0.0 0.078 13.2 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 CCC71215.1 - 0.073 12.6 1.9 2.5 7.6 0.1 2.5 2 1 0 3 3 3 0 Ferrous iron transport protein B PduV-EutP PF10662.9 CCC71215.1 - 0.076 12.8 0.2 1.2 8.8 0.2 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 CCC71215.1 - 0.078 12.7 0.4 0.18 11.5 0.1 1.8 2 1 0 2 2 2 0 AAA domain Flavodoxin_1 PF00258.25 CCC71216.1 - 1.2e-08 35.3 0.1 2.7e-08 34.1 0.0 1.5 2 0 0 2 2 2 1 Flavodoxin FMN_red PF03358.15 CCC71216.1 - 1.9e-06 27.7 0.1 4.7e-06 26.4 0.0 1.8 2 1 0 2 2 2 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.7 CCC71216.1 - 0.009 16.2 0.0 0.038 14.2 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_2 PF02525.17 CCC71216.1 - 0.012 15.4 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin-like fold MSP1_C PF07462.11 CCC71216.1 - 5.1 5.7 4.2 6.8 5.3 4.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus DUF4611 PF15387.6 CCC71218.1 - 0.19 12.0 5.8 32 4.8 0.0 3.3 2 1 0 3 3 3 0 Domain of unknown function (DUF4611) CN_hydrolase PF00795.22 CCC71219.1 - 7.9e-62 208.9 0.0 8.9e-62 208.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Gsf2 PF11055.8 CCC71220.1 - 2.3e-179 596.0 0.5 2.7e-179 595.7 0.5 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 MMS1_N PF10433.9 CCC71221.1 - 1.4e-69 235.0 14.4 1.4e-69 235.0 12.2 2.1 3 0 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 CCC71221.1 - 3.8e-51 174.3 0.4 1.2e-47 162.8 0.0 2.7 2 1 0 2 2 2 2 CPSF A subunit region YL1 PF05764.13 CCC71221.1 - 0.061 13.4 1.7 0.12 12.4 1.7 1.4 1 0 0 1 1 1 0 YL1 nuclear protein SMI1_KNR4 PF09346.10 CCC71221.1 - 0.31 11.4 4.6 0.73 10.2 0.2 3.4 4 0 0 4 4 4 0 SMI1 / KNR4 family (SUKH-1) E7 PF00527.18 CCC71221.1 - 0.58 10.4 5.0 2.4 8.4 0.6 2.6 2 0 0 2 2 2 0 E7 protein, Early protein FAM176 PF14851.6 CCC71221.1 - 4.8 6.8 7.7 13 5.4 2.7 2.6 2 0 0 2 2 2 0 FAM176 family CENP-B_dimeris PF09026.10 CCC71221.1 - 7.6 7.0 17.7 1.8 9.0 7.6 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Suc_Fer-like PF06999.12 CCC71222.1 - 3.6e-32 111.8 0.0 4.4e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 Sucrase/ferredoxin-like GFO_IDH_MocA PF01408.22 CCC71223.1 - 8.5e-09 36.3 0.0 1.2e-08 35.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 CCC71223.1 - 0.014 15.4 0.0 0.035 14.1 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain SUR7 PF06687.12 CCC71224.1 - 8e-39 133.5 10.9 9.8e-39 133.2 10.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 CCC71224.1 - 0.00018 21.5 2.5 0.00032 20.7 2.5 1.4 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 Anoctamin PF04547.12 CCC71224.1 - 0.0048 15.8 0.4 0.0072 15.2 0.4 1.3 1 0 0 1 1 1 1 Calcium-activated chloride channel Claudin_2 PF13903.6 CCC71224.1 - 0.15 11.8 8.6 0.087 12.6 6.6 1.6 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF1077 PF06417.12 CCC71224.1 - 0.28 11.2 2.8 3.5 7.7 2.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) DUF805 PF05656.14 CCC71224.1 - 1.1 9.7 10.3 0.18 12.3 6.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF805) DUF3810 PF12725.7 CCC71224.1 - 2.2 7.5 5.3 3.4 6.9 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Thymidylate_kin PF02223.17 CCC71226.1 - 1.6e-47 161.6 0.0 1.9e-47 161.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_18 PF13238.6 CCC71226.1 - 0.019 15.5 0.0 0.032 14.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF643 PF04867.12 CCC71226.1 - 0.031 14.9 0.5 0.4 11.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF643) KTI12 PF08433.10 CCC71226.1 - 0.054 12.9 0.7 0.28 10.6 0.7 1.9 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Kinase-PPPase PF03618.14 CCC71226.1 - 0.16 11.7 0.1 0.5 10.1 0.0 1.8 2 0 0 2 2 2 0 Kinase/pyrophosphorylase Clat_adaptor_s PF01217.20 CCC71227.1 - 2.6e-52 176.6 2.5 3.7e-50 169.6 2.5 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AAA PF00004.29 CCC71228.1 - 2.8e-53 179.9 0.0 9.7e-44 149.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 CCC71228.1 - 4.7e-22 78.2 4.9 7.7e-22 77.5 0.8 3.3 4 0 0 4 4 2 1 Peroxisome biogenesis factor 1, N-terminal AAA_lid_3 PF17862.1 CCC71228.1 - 7.3e-11 41.7 0.0 4e-08 32.9 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 CCC71228.1 - 1.3e-10 41.9 0.1 0.0006 20.2 0.0 3.6 2 1 1 3 3 3 2 AAA ATPase domain AAA_18 PF13238.6 CCC71228.1 - 2e-08 34.8 0.0 0.0056 17.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CCC71228.1 - 2.6e-07 30.7 0.0 0.0064 16.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 CCC71228.1 - 6.5e-07 29.4 2.7 0.0094 15.9 0.3 4.3 4 1 0 4 4 4 2 NACHT domain AAA_22 PF13401.6 CCC71228.1 - 2.2e-06 28.0 0.3 0.18 12.1 0.0 4.2 3 2 1 4 4 3 2 AAA domain AAA_33 PF13671.6 CCC71228.1 - 3.4e-06 27.3 0.0 0.12 12.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CCC71228.1 - 4.1e-06 26.2 0.2 0.059 12.6 0.0 3.0 3 0 0 3 3 3 2 TIP49 P-loop domain RuvB_N PF05496.12 CCC71228.1 - 6.2e-06 26.0 0.0 0.0031 17.3 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CCC71228.1 - 1e-05 25.3 0.0 0.22 11.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 CCC71228.1 - 1.2e-05 25.3 0.0 0.16 12.0 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.18 CCC71228.1 - 2.3e-05 24.3 0.0 0.2 11.4 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.14 CCC71228.1 - 5.8e-05 23.3 0.0 0.012 15.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 CCC71228.1 - 6.6e-05 22.3 0.0 0.039 13.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.6 CCC71228.1 - 6.9e-05 22.7 0.0 0.045 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CCC71228.1 - 7.1e-05 23.2 1.0 0.22 11.9 0.0 3.7 4 0 0 4 4 2 1 AAA domain TsaE PF02367.17 CCC71228.1 - 0.0001 22.3 0.0 0.11 12.5 0.0 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 CCC71228.1 - 0.00012 21.6 0.1 0.58 9.5 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 CCC71228.1 - 0.00018 21.4 0.0 0.22 11.4 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 CCC71228.1 - 0.00027 21.3 0.0 0.45 10.9 0.0 3.2 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 CCC71228.1 - 0.00037 20.1 1.4 0.63 9.6 0.1 3.8 3 2 1 5 5 4 1 AAA domain AAA_28 PF13521.6 CCC71228.1 - 0.00041 20.6 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.9 CCC71228.1 - 0.00042 19.7 0.0 0.89 8.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Rad17 PF03215.15 CCC71228.1 - 0.00044 20.2 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 2 Rad17 P-loop domain NB-ARC PF00931.22 CCC71228.1 - 0.00067 18.9 1.8 0.64 9.1 0.0 3.6 4 0 0 4 4 4 2 NB-ARC domain ABC_tran PF00005.27 CCC71228.1 - 0.0007 20.1 0.2 0.99 9.9 0.0 3.2 3 0 0 3 3 2 1 ABC transporter ATP_bind_1 PF03029.17 CCC71228.1 - 0.0012 18.7 0.0 0.0045 16.8 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 CCC71228.1 - 0.0021 17.8 0.0 0.037 13.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CCC71228.1 - 0.0028 17.2 0.1 0.81 9.2 0.0 2.8 3 0 0 3 3 2 1 P-loop containing dynein motor region Sigma54_activat PF00158.26 CCC71228.1 - 0.0028 17.4 0.0 7.4 6.3 0.0 3.6 3 1 0 4 4 3 0 Sigma-54 interaction domain T2SSE PF00437.20 CCC71228.1 - 0.0029 16.7 0.6 0.059 12.4 0.2 2.8 2 1 1 3 3 3 1 Type II/IV secretion system protein NTPase_1 PF03266.15 CCC71228.1 - 0.0045 16.9 0.0 0.23 11.4 0.0 2.5 2 0 0 2 2 2 1 NTPase AAA_29 PF13555.6 CCC71228.1 - 0.0048 16.6 0.0 0.11 12.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.6 CCC71228.1 - 0.0054 17.1 0.2 0.4 11.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 CCC71228.1 - 0.0056 16.6 1.2 1.4 8.8 0.0 3.4 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea ATPase PF06745.13 CCC71228.1 - 0.0063 15.9 0.2 3.6 6.9 0.0 2.8 3 0 0 3 3 2 1 KaiC cobW PF02492.19 CCC71228.1 - 0.015 14.9 0.6 0.64 9.6 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_11 PF13086.6 CCC71228.1 - 0.03 14.1 1.0 0.95 9.2 0.0 3.1 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 CCC71228.1 - 0.043 13.2 0.0 22 4.4 0.0 4.0 4 0 0 4 4 4 0 Bacterial TniB protein KTI12 PF08433.10 CCC71228.1 - 0.054 12.9 1.4 1.3 8.5 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Bac_DnaA PF00308.18 CCC71228.1 - 0.056 13.3 0.0 9.8 5.9 0.0 2.6 2 0 0 2 2 2 0 Bacterial dnaA protein Parvo_NS1 PF01057.17 CCC71228.1 - 0.091 11.8 0.0 0.4 9.7 0.0 2.0 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 MMR_HSR1 PF01926.23 CCC71228.1 - 0.15 12.1 0.5 26 4.9 0.0 3.4 3 0 0 3 3 3 0 50S ribosome-binding GTPase Pkinase PF00069.25 CCC71229.1 - 1e-36 126.7 0.1 3.8e-36 124.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71229.1 - 3.4e-17 62.6 0.0 7.6e-17 61.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCC71229.1 - 0.00021 20.7 0.0 0.00036 19.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4999 PF16390.5 CCC71229.1 - 0.014 15.6 0.0 0.036 14.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function Kinase-like PF14531.6 CCC71229.1 - 0.071 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like LicD PF04991.13 CCC71230.1 - 4e-61 207.0 3.8 4e-61 207.0 3.8 3.1 4 1 0 4 4 4 1 LicD family SAM_3 PF18016.1 CCC71230.1 - 0.066 13.0 0.6 0.35 10.7 0.0 2.4 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) DUF2115 PF09888.9 CCC71230.1 - 0.37 11.3 2.4 0.87 10.1 0.1 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2115) FAT PF02259.23 CCC71231.1 - 1.6e-132 442.0 0.0 1.6e-132 442.0 0.0 1.9 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 CCC71231.1 - 1.2e-72 244.7 0.0 2.8e-72 243.6 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 CCC71231.1 - 3.1e-69 232.0 9.5 1.5e-66 223.2 0.3 5.3 4 2 1 5 5 5 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 CCC71231.1 - 2.7e-42 143.2 3.8 5.1e-42 142.3 0.4 2.9 2 0 0 2 2 2 1 FKBP12-rapamycin binding domain FATC PF02260.20 CCC71231.1 - 1e-17 63.6 0.2 2.3e-17 62.5 0.2 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.6 CCC71231.1 - 9.9e-12 45.1 5.2 0.0017 18.7 0.1 8.3 7 2 1 8 8 8 2 HEAT repeats HEAT PF02985.22 CCC71231.1 - 6.6e-08 32.2 8.3 0.019 15.2 0.0 7.6 9 0 0 9 9 8 2 HEAT repeat HEAT_EZ PF13513.6 CCC71231.1 - 5e-07 30.1 10.6 0.0031 18.0 0.1 7.8 7 1 2 9 9 8 3 HEAT-like repeat IFRD PF05004.13 CCC71231.1 - 6e-05 22.3 0.8 0.014 14.5 0.0 3.8 3 1 0 4 4 4 1 Interferon-related developmental regulator (IFRD) Vac14_Fab1_bd PF12755.7 CCC71231.1 - 0.015 15.9 0.8 1.2 9.7 0.0 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 CCC71231.1 - 0.027 14.0 6.0 5.7 6.4 0.0 4.5 5 0 0 5 5 5 0 CLASP N terminal Imm30 PF15565.6 CCC71231.1 - 0.13 12.3 0.2 1.3 9.1 0.0 2.9 2 0 0 2 2 2 0 Immunity protein 30 DUF3673 PF12425.8 CCC71231.1 - 0.14 12.1 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3673) MOR2-PAG1_C PF14225.6 CCC71231.1 - 2 8.2 7.4 8.2 6.2 0.1 3.9 4 0 0 4 4 4 0 Cell morphogenesis C-terminal Xpo1 PF08389.12 CCC71232.1 - 4e-33 114.6 7.6 1.3e-32 113.0 1.7 3.8 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 CCC71232.1 - 0.016 15.1 1.4 0.11 12.5 0.6 2.7 2 0 0 2 2 2 0 Importin-beta N-terminal domain Ham1p_like PF01725.16 CCC71233.1 - 1.7e-50 171.5 0.0 2e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family HEAT_2 PF13646.6 CCC71234.1 - 1e-35 121.9 1.4 2.4e-16 59.9 0.1 3.3 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 CCC71234.1 - 1.9e-22 77.6 0.9 6.6e-06 26.3 0.4 6.4 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.22 CCC71234.1 - 8e-13 47.5 1.2 0.29 11.5 0.0 5.4 5 0 0 5 5 5 4 HEAT repeat HEAT_EZ PF13513.6 CCC71234.1 - 3.2e-05 24.3 7.3 0.53 10.9 0.3 5.5 4 2 2 6 6 6 3 HEAT-like repeat Cnd1 PF12717.7 CCC71234.1 - 0.00049 20.2 0.4 0.74 9.8 0.0 3.5 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 CCC71234.1 - 0.11 11.1 0.4 1.6 7.2 0.0 2.4 2 1 0 2 2 2 0 Adaptin N terminal region ATP_bind_1 PF03029.17 CCC71235.1 - 6.2e-82 275.0 0.1 1e-81 274.3 0.1 1.3 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 CCC71235.1 - 1.9e-06 27.6 0.1 5.2e-05 22.9 0.1 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 CCC71235.1 - 0.00017 21.6 0.0 0.0029 17.7 0.0 2.6 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 CCC71235.1 - 0.00017 21.8 0.0 0.00047 20.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 CCC71235.1 - 0.00029 20.6 0.1 0.0009 19.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 CCC71235.1 - 0.00041 19.4 0.0 0.43 9.5 0.0 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 CCC71235.1 - 0.00055 19.9 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 NACHT domain PduV-EutP PF10662.9 CCC71235.1 - 0.0011 18.8 0.0 0.048 13.4 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation CLP1_P PF16575.5 CCC71235.1 - 0.002 17.9 0.0 1 9.2 0.0 2.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_22 PF13401.6 CCC71235.1 - 0.0021 18.3 0.1 0.013 15.8 0.0 2.3 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 CCC71235.1 - 0.0026 17.7 0.3 5.2 7.0 0.0 3.3 2 1 0 2 2 2 2 RsgA GTPase cobW PF02492.19 CCC71235.1 - 0.0037 16.9 0.1 0.025 14.1 0.1 2.2 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 CCC71235.1 - 0.0042 16.6 0.0 0.082 12.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B SRP54 PF00448.22 CCC71235.1 - 0.0054 16.4 0.0 0.051 13.2 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Roc PF08477.13 CCC71235.1 - 0.007 16.6 0.0 0.54 10.5 0.0 2.7 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 CCC71235.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 CCC71235.1 - 0.016 15.6 0.0 0.037 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PRK PF00485.18 CCC71235.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Arf PF00025.21 CCC71235.1 - 0.019 14.4 0.0 1.4 8.3 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family NB-ARC PF00931.22 CCC71235.1 - 0.027 13.7 0.0 0.064 12.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.10 CCC71235.1 - 0.027 13.9 0.0 0.061 12.8 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ATP-synt_E PF05680.12 CCC71235.1 - 0.027 14.8 1.2 0.066 13.5 1.2 1.6 1 0 0 1 1 1 0 ATP synthase E chain AAA_30 PF13604.6 CCC71235.1 - 0.029 14.1 0.0 0.058 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 CCC71235.1 - 0.065 13.8 0.0 0.065 13.8 0.0 2.7 3 1 0 3 3 1 0 AAA domain NTPase_1 PF03266.15 CCC71235.1 - 0.074 13.0 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 NTPase SRPRB PF09439.10 CCC71235.1 - 0.14 11.6 3.7 0.65 9.4 0.0 2.6 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF87 PF01935.17 CCC71235.1 - 0.23 11.5 3.9 3.7 7.6 0.0 2.5 2 1 0 2 2 2 0 Helicase HerA, central domain EMC3_TMCO1 PF01956.16 CCC71236.1 - 3.8e-56 189.5 1.9 4.6e-56 189.2 1.9 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like ABC_membrane PF00664.23 CCC71238.1 - 9.2e-104 346.9 40.4 9.8e-58 196.0 16.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 CCC71238.1 - 2.7e-64 215.8 0.6 3.4e-31 108.6 0.1 3.1 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 CCC71238.1 - 3.3e-17 62.7 0.0 8.6e-06 25.3 1.0 4.8 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 CCC71238.1 - 1.4e-08 34.8 0.0 0.0004 20.2 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 CCC71238.1 - 1.6e-08 34.9 0.4 0.0032 17.7 0.1 3.5 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 CCC71238.1 - 7.7e-08 32.4 0.0 0.022 14.7 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 CCC71238.1 - 1.2e-07 31.3 5.3 0.0037 17.0 0.1 3.4 4 0 0 4 4 3 2 P-loop containing region of AAA domain AAA_21 PF13304.6 CCC71238.1 - 1.5e-06 28.3 2.6 0.71 9.6 0.8 3.8 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 CCC71238.1 - 3.9e-06 27.3 0.0 0.077 13.4 0.0 3.4 3 0 0 3 3 3 2 AAA ATPase domain ABC_ATPase PF09818.9 CCC71238.1 - 5.2e-06 25.5 0.0 0.035 12.9 0.0 3.1 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_23 PF13476.6 CCC71238.1 - 1.6e-05 25.5 1.7 0.25 11.8 0.1 3.2 3 0 0 3 3 3 2 AAA domain Ploopntkinase3 PF18751.1 CCC71238.1 - 3.5e-05 23.8 0.0 0.039 13.9 0.0 2.3 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 MMR_HSR1 PF01926.23 CCC71238.1 - 3.7e-05 23.8 0.1 0.41 10.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.6 CCC71238.1 - 8.9e-05 23.0 0.0 0.72 10.4 0.0 3.7 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 CCC71238.1 - 0.00026 20.3 0.0 0.076 12.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin G-alpha PF00503.20 CCC71238.1 - 0.00026 20.3 1.5 0.14 11.3 0.0 2.8 3 1 0 3 3 2 2 G-protein alpha subunit RNA_helicase PF00910.22 CCC71238.1 - 0.00042 20.7 0.0 1.3 9.5 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.14 CCC71238.1 - 0.00048 20.1 0.1 2.8 7.9 0.0 3.5 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 CCC71238.1 - 0.00072 19.5 0.2 0.42 10.5 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_30 PF13604.6 CCC71238.1 - 0.00079 19.2 0.0 1 9.0 0.0 2.9 4 0 0 4 4 2 1 AAA domain DUF87 PF01935.17 CCC71238.1 - 0.00097 19.3 2.4 1.6 8.7 0.0 3.3 3 0 0 3 3 3 2 Helicase HerA, central domain AAA_24 PF13479.6 CCC71238.1 - 0.0013 18.5 0.1 0.5 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 CCC71238.1 - 0.0017 18.4 1.3 5.9 6.9 0.0 4.5 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 CCC71238.1 - 0.002 18.3 0.1 0.63 10.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF3987 PF13148.6 CCC71238.1 - 0.0064 15.5 0.0 0.44 9.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) NB-ARC PF00931.22 CCC71238.1 - 0.0066 15.7 0.0 2.6 7.2 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain Roc PF08477.13 CCC71238.1 - 0.0068 16.6 0.7 10 6.4 0.0 3.4 3 1 1 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_13 PF13166.6 CCC71238.1 - 0.012 14.3 0.2 0.012 14.3 0.2 2.6 3 0 0 3 3 3 0 AAA domain PRK PF00485.18 CCC71238.1 - 0.012 15.4 0.0 0.53 10.0 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family T2SSE PF00437.20 CCC71238.1 - 0.012 14.7 0.0 1.3 8.0 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein Pox_A32 PF04665.12 CCC71238.1 - 0.031 13.7 0.9 6.1 6.2 0.1 2.8 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_7 PF12775.7 CCC71238.1 - 0.041 13.4 0.2 7.4 6.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 CCC71238.1 - 0.05 13.5 1.9 5.1 7.0 0.2 2.8 2 0 0 2 2 2 0 NACHT domain Septin PF00735.18 CCC71238.1 - 0.054 12.8 0.1 11 5.2 0.0 2.5 2 0 0 2 2 2 0 Septin ATP_bind_1 PF03029.17 CCC71238.1 - 0.059 13.1 0.1 16 5.2 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF815 PF05673.13 CCC71238.1 - 0.065 12.4 0.0 3.2 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.9 CCC71238.1 - 0.14 11.9 1.9 12 5.6 0.1 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation MobB PF03205.14 CCC71238.1 - 0.14 12.0 0.6 15 5.5 0.0 3.0 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.23 CCC71238.1 - 0.42 10.7 1.2 8 6.5 0.1 2.6 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 CCC71238.1 - 1 8.9 3.6 13 5.3 0.1 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 CCC71238.1 - 1.8 8.4 4.6 6.9 6.5 0.0 3.6 4 1 1 5 5 4 0 ATPase domain predominantly from Archaea DUF2207 PF09972.9 CCC71238.1 - 5.9 5.5 12.8 0.071 11.9 0.2 2.6 2 1 0 2 2 1 0 Predicted membrane protein (DUF2207) GATA PF00320.27 CCC71239.1 - 3.3e-14 52.2 4.5 5.7e-14 51.4 4.5 1.4 1 0 0 1 1 1 1 GATA zinc finger ThiF PF00899.21 CCC71240.1 - 3.8e-111 370.3 0.0 2.4e-76 256.3 0.0 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 CCC71240.1 - 1.7e-88 296.8 0.1 2.6e-88 296.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 CCC71240.1 - 5.2e-34 116.8 0.2 2e-33 114.9 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin fold domain E1_FCCH PF16190.5 CCC71240.1 - 4.5e-26 90.8 0.3 1.2e-25 89.5 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 CCC71240.1 - 4.1e-25 87.7 0.3 1e-24 86.5 0.3 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle Gly_transf_sug PF04488.15 CCC71241.1 - 6.1e-13 49.2 0.0 1.9e-12 47.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif ARGLU PF15346.6 CCC71241.1 - 1.4 8.8 13.0 1.8 8.4 8.2 2.3 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 Septin PF00735.18 CCC71242.1 - 2.9e-106 354.9 0.0 5.2e-106 354.0 0.0 1.4 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CCC71242.1 - 2.3e-08 34.1 0.0 5.7e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 CCC71242.1 - 2.3e-05 24.5 9.3 0.00075 19.6 0.2 3.0 2 1 1 3 3 3 2 Dynamin family RsgA_GTPase PF03193.16 CCC71242.1 - 3.8e-05 23.7 6.1 4.9e-05 23.3 0.6 2.8 3 1 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 CCC71242.1 - 4.3e-05 22.9 0.1 4.3e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.27 CCC71242.1 - 0.00059 20.4 1.4 0.00097 19.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter IIGP PF05049.13 CCC71242.1 - 0.0024 17.0 0.1 0.0044 16.1 0.1 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.18 CCC71242.1 - 0.0052 16.3 0.6 0.053 13.1 0.6 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 CCC71242.1 - 0.066 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 CCC71242.1 - 0.08 13.4 8.4 0.25 11.8 2.9 2.5 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.9 CCC71242.1 - 0.1 12.3 0.2 1.8 8.3 0.2 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 CCC71242.1 - 0.3 10.2 2.8 0.43 9.7 0.1 2.4 3 0 0 3 3 3 0 G-protein alpha subunit IGPS PF00218.21 CCC71243.1 - 2.5e-88 295.5 0.1 3.3e-88 295.1 0.1 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.28 CCC71243.1 - 3.1e-49 167.4 0.1 4.8e-49 166.7 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 CCC71243.1 - 4.5e-09 36.4 0.5 1.6e-08 34.6 0.5 1.8 1 1 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.19 CCC71243.1 - 0.00032 20.5 0.1 0.00093 19.0 0.1 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Syja_N PF02383.18 CCC71244.1 - 5.2e-83 279.0 1.6 7.3e-83 278.5 1.6 1.2 1 0 0 1 1 1 1 SacI homology domain InaF-motif PF15018.6 CCC71244.1 - 0.0007 19.4 0.2 0.0007 19.4 0.2 1.9 2 0 0 2 2 2 1 TRP-interacting helix Meiosis_expr PF15163.6 CCC71244.1 - 0.1 13.3 1.4 0.28 11.9 1.4 1.7 1 0 0 1 1 1 0 Meiosis-expressed Ribosomal_L30 PF00327.20 CCC71245.1 - 6.5e-12 45.2 0.7 1.8e-11 43.8 0.7 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RNA_pol_3_Rpc31 PF11705.8 CCC71245.1 - 0.62 10.3 10.1 1 9.6 10.1 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Peptidase_C1_2 PF03051.15 CCC71246.1 - 4.3e-156 520.1 0.6 4.9e-156 519.9 0.6 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.23 CCC71246.1 - 1.1e-06 29.0 0.0 0.015 15.4 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease WD40 PF00400.32 CCC71247.1 - 9.3e-43 143.4 17.1 1.6e-10 41.4 0.1 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC71247.1 - 1.7e-12 47.5 3.3 0.0025 18.1 0.1 5.2 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCC71247.1 - 3.7e-08 32.5 11.2 0.009 14.7 0.1 4.7 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 CCC71247.1 - 2.1e-06 26.5 0.3 2.3e-05 23.1 0.2 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 CCC71247.1 - 5.3e-06 25.4 1.4 0.31 9.8 0.0 3.9 1 1 3 4 4 4 2 Nup133 N terminal like Ge1_WD40 PF16529.5 CCC71247.1 - 5.5e-06 25.6 2.7 0.47 9.4 0.0 4.5 1 1 5 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 CCC71247.1 - 0.00051 19.8 0.6 0.027 14.2 0.1 3.7 2 1 1 3 3 3 2 TUP1-like enhancer of split DUF1513 PF07433.11 CCC71247.1 - 0.0027 16.8 0.3 2.4 7.2 0.0 3.1 1 1 3 4 4 4 2 Protein of unknown function (DUF1513) Frtz PF11768.8 CCC71247.1 - 0.0032 15.9 0.0 0.014 13.7 0.0 2.0 2 1 1 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz PALB2_WD40 PF16756.5 CCC71247.1 - 0.0046 15.9 3.1 0.012 14.5 0.1 2.8 3 1 0 3 3 3 1 Partner and localizer of BRCA2 WD40 domain Utp8 PF10395.9 CCC71247.1 - 0.028 12.9 0.0 2.1 6.8 0.0 2.1 1 1 1 2 2 2 0 Utp8 family DnaJ_C PF01556.18 CCC71248.1 - 4.5e-34 117.7 0.0 5.9e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 CCC71248.1 - 1.2e-21 76.5 1.6 1.5e-21 76.3 0.2 1.8 2 0 0 2 2 2 1 DnaJ domain Iso_dh PF00180.20 CCC71249.1 - 8.5e-65 219.2 0.0 9.9e-65 219.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HAD PF12710.7 CCC71250.1 - 8.2e-23 81.8 0.0 1e-22 81.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 CCC71250.1 - 4.4e-05 23.0 0.0 0.00027 20.4 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase UMPH-1 PF05822.12 CCC71250.1 - 0.0002 20.9 0.0 0.0011 18.6 0.0 2.0 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) Hydrolase PF00702.26 CCC71250.1 - 0.0017 18.7 0.4 0.19 12.0 0.0 3.1 2 1 2 4 4 4 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 CCC71250.1 - 0.022 14.9 0.4 2.3 8.2 0.1 2.7 1 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase UPF0052 PF01933.18 CCC71251.1 - 4.2e-65 219.9 0.1 5.6e-65 219.5 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 DUF3842 PF12953.7 CCC71251.1 - 0.12 12.7 0.3 0.3 11.5 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3842) PLA2_B PF01735.18 CCC71252.1 - 5.3e-79 265.9 18.3 1.3e-62 211.8 7.8 3.1 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Patatin PF01734.22 CCC71252.1 - 0.055 13.6 0.0 0.18 11.9 0.0 2.1 1 1 0 1 1 1 0 Patatin-like phospholipase NDUFB10 PF10249.9 CCC71252.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 Inhibitor_I9 PF05922.16 CCC71253.1 - 0.00012 22.6 0.2 0.00028 21.5 0.2 1.6 1 1 0 1 1 1 1 Peptidase inhibitor I9 PurS PF02700.14 CCC71253.1 - 0.0061 16.7 0.2 0.0089 16.2 0.2 1.3 1 1 0 1 1 1 1 Phosphoribosylformylglycinamidine (FGAM) synthase Frataxin_Cyay PF01491.16 CCC71254.1 - 1.3e-31 108.8 0.0 1.8e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain UCH PF00443.29 CCC71255.1 - 1.1e-40 139.8 5.3 1.4e-40 139.4 5.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCC71255.1 - 1.3e-10 41.4 9.0 8.3e-09 35.5 9.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Y_phosphatase2 PF03162.13 CCC71256.1 - 1.2e-64 216.9 0.0 1.9e-64 216.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 CCC71256.1 - 1.1e-06 28.8 0.0 1.9e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.20 CCC71256.1 - 0.0024 17.7 0.0 0.0047 16.8 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 CCC71256.1 - 0.0074 15.9 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Glyco_transf_25 PF01755.17 CCC71256.1 - 0.1 12.5 0.7 0.19 11.6 0.7 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Histone PF00125.24 CCC71257.1 - 3.1e-49 166.7 3.4 3.4e-49 166.5 3.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 CCC71257.1 - 2e-06 28.1 0.0 3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 CCC71257.1 - 5.5e-05 23.8 1.3 6.9e-05 23.5 1.3 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 CCC71257.1 - 0.00011 22.3 0.8 0.00015 21.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 CCC71257.1 - 0.0018 18.5 0.9 0.0023 18.2 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 CCC71257.1 - 0.035 14.2 0.2 0.058 13.5 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 CCC71258.1 - 1.9e-09 37.6 0.1 2.2e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 CCC71258.1 - 2.1e-05 24.9 0.1 2.5e-05 24.7 0.1 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 CCC71258.1 - 3e-05 24.1 0.1 4.2e-05 23.6 0.1 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 CCC71258.1 - 3.6e-05 24.0 0.1 6.1e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 CCC71258.1 - 0.00017 21.9 0.1 0.00023 21.5 0.1 1.4 1 1 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 CCC71258.1 - 0.0029 17.7 0.0 0.0035 17.4 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 CCC71258.1 - 0.0067 16.4 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.13 CCC71258.1 - 0.043 14.3 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Glyco_transf_15 PF01793.16 CCC71259.1 - 1.3e-86 290.8 18.2 7e-57 193.1 5.5 2.2 1 1 1 2 2 2 2 Glycolipid 2-alpha-mannosyltransferase zf-H2C2_2 PF13465.6 CCC71260.1 - 2.9e-13 49.6 11.5 5.5e-08 32.9 0.5 4.2 3 1 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.26 CCC71260.1 - 3.2e-09 36.7 29.1 4.7e-07 29.9 1.2 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-met PF12874.7 CCC71260.1 - 8.8e-07 29.1 5.2 2.4e-05 24.6 0.3 3.1 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCC71260.1 - 1e-06 28.9 7.1 0.00055 20.1 0.2 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.6 CCC71260.1 - 5.1e-06 26.4 8.0 0.0053 16.7 0.3 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.6 CCC71260.1 - 0.00026 21.5 0.8 0.00026 21.5 0.8 4.0 4 0 0 4 4 4 3 C2H2-type zinc finger Zn_ribbon_recom PF13408.6 CCC71260.1 - 0.0082 16.6 3.7 0.0082 16.6 3.7 2.5 3 1 0 3 3 3 1 Recombinase zinc beta ribbon domain zf-C2HE PF16278.5 CCC71260.1 - 0.074 13.5 1.2 3.9 8.0 0.1 3.1 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Zn-ribbon_8 PF09723.10 CCC71260.1 - 0.17 12.0 0.9 0.41 10.8 0.9 1.7 1 0 0 1 1 1 0 Zinc ribbon domain Met_10 PF02475.16 CCC71261.1 - 3.4e-09 36.7 0.0 6e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 CCC71261.1 - 0.0032 17.0 0.0 0.0057 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.11 CCC71261.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_32 PF13679.6 CCC71261.1 - 0.045 13.7 0.0 0.073 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 CCC71261.1 - 0.056 13.2 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 CCC71261.1 - 0.069 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Bac_surface_Ag PF01103.23 CCC71262.1 - 4.2e-41 141.5 6.0 5.3e-41 141.2 6.0 1.1 1 0 0 1 1 1 1 Surface antigen DUF1242 PF06842.12 CCC71263.1 - 3e-16 58.9 0.3 3.9e-16 58.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Methyltransf_16 PF10294.9 CCC71264.1 - 1.7e-49 167.9 0.0 2.7e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CCC71264.1 - 0.0093 15.5 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CCC71264.1 - 0.21 10.9 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) R3H PF01424.22 CCC71265.1 - 1.6e-15 56.8 0.1 3.2e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.17 CCC71265.1 - 4.5e-11 42.6 56.0 6.8e-06 26.0 17.5 12.6 12 2 0 12 12 12 5 NF-X1 type zinc finger Methyltr_RsmB-F PF01189.17 CCC71266.1 - 1.7e-19 70.3 0.0 3.9e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F PRMT5 PF05185.16 CCC71266.1 - 0.017 15.0 0.1 0.23 11.3 0.0 2.2 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Arb2 PF09757.9 CCC71267.1 - 2.7e-98 328.2 0.2 4.2e-98 327.6 0.2 1.3 1 0 0 1 1 1 1 Arb2 domain Hist_deacetyl PF00850.19 CCC71267.1 - 2.7e-88 296.4 0.0 4e-88 295.8 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Pkinase PF00069.25 CCC71268.1 - 1.1e-38 133.1 0.5 2e-38 132.2 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71268.1 - 4.3e-29 101.6 0.0 9.8e-29 100.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC71268.1 - 0.00018 20.9 0.9 0.0009 18.6 0.0 2.4 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 CCC71268.1 - 0.049 13.5 0.0 0.76 9.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 CCC71268.1 - 0.058 12.2 3.1 0.094 11.5 0.0 2.3 2 1 0 2 2 2 0 Fungal protein kinase Epimerase PF01370.21 CCC71269.1 - 2.4e-16 59.9 0.0 3.6e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCC71269.1 - 9.6e-11 41.2 0.0 1.3e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CCC71269.1 - 5.5e-09 35.6 0.0 1.2e-07 31.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 CCC71269.1 - 2.8e-07 30.3 0.1 1.8e-06 27.6 0.1 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 CCC71269.1 - 1.5e-06 28.2 0.0 3e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CCC71269.1 - 3e-05 23.7 0.1 0.012 15.1 0.1 2.2 2 0 0 2 2 2 2 NmrA-like family Polysacc_synt_2 PF02719.15 CCC71269.1 - 4.7e-05 22.7 0.2 6.2e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 CCC71269.1 - 0.00022 20.8 0.2 0.0019 17.7 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 CCC71269.1 - 0.0059 16.5 0.1 0.018 14.9 0.1 1.8 2 0 0 2 2 2 1 KR domain DUF1761 PF08570.10 CCC71270.1 - 0.078 13.2 0.3 4 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) Methyltransf_16 PF10294.9 CCC71272.1 - 1.7e-49 167.9 0.0 2.7e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 CCC71272.1 - 0.0093 15.5 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 CCC71272.1 - 0.21 10.9 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Bac_surface_Ag PF01103.23 CCC71273.1 - 4.2e-41 141.5 6.0 5.3e-41 141.2 6.0 1.1 1 0 0 1 1 1 1 Surface antigen WD40 PF00400.32 CCC71274.1 - 8.2e-10 39.1 3.7 0.00038 21.2 0.5 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC71274.1 - 6.8e-05 23.1 0.3 0.092 13.1 0.0 3.7 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 CCC71274.1 - 0.013 14.3 0.6 0.43 9.3 0.0 2.1 1 1 1 2 2 2 0 Nup133 N terminal like Myb_DNA-bind_7 PF15963.5 CCC71275.1 - 1.9e-25 88.6 0.1 1.9e-25 88.6 0.1 3.4 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 CCC71275.1 - 1.2e-07 31.8 0.0 4.4e-07 30.0 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCC71275.1 - 0.018 15.3 0.5 0.11 12.7 0.1 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain PulA_N1 PF17999.1 CCC71275.1 - 0.095 13.5 0.8 27 5.6 0.0 3.2 3 1 0 3 3 3 0 Pullulanase N1-terminal domain SOSSC PF15925.5 CCC71275.1 - 4.1 8.8 8.5 1.1 10.6 0.5 3.4 2 1 0 2 2 2 0 SOSS complex subunit C PIG-H PF10181.9 CCC71276.1 - 2.9e-21 75.1 1.5 3.2e-21 75.0 0.3 1.7 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component Glyco_hydro_15 PF00723.21 CCC71277.1 - 5.5e-52 177.0 0.0 6.8e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Pro_CA PF00484.19 CCC71278.1 - 1.1e-37 129.8 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase COG6 PF06419.11 CCC71280.1 - 3.2e-163 544.3 35.6 3.2e-163 544.3 35.6 1.8 2 0 0 2 2 2 1 Conserved oligomeric complex COG6 RTBV_P12 PF06361.11 CCC71280.1 - 0.019 15.4 9.5 0.51 10.8 0.3 4.3 5 0 0 5 5 5 0 Rice tungro bacilliform virus P12 protein ApoB100_C PF12491.8 CCC71280.1 - 0.027 14.4 0.4 0.027 14.4 0.4 3.6 3 0 0 3 3 3 0 Apolipoprotein B100 C terminal DUF2722 PF10846.8 CCC71281.1 - 2.8e-38 132.1 27.5 4.6e-38 131.4 27.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Bcl-2_BAD PF10514.9 CCC71281.1 - 0.051 14.1 0.0 0.13 12.7 0.0 1.8 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD zf-Nse PF11789.8 CCC71282.1 - 4.5e-22 77.6 0.2 1.2e-21 76.3 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CCC71282.1 - 1.2e-05 25.2 1.9 3.3e-05 23.8 1.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CCC71282.1 - 3.3e-05 23.6 0.2 8.7e-05 22.3 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 CCC71282.1 - 0.00038 19.9 0.1 0.00038 19.9 0.1 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.25 CCC71282.1 - 0.00072 19.4 0.2 0.0018 18.1 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 CCC71282.1 - 0.0016 18.7 1.2 0.0048 17.2 1.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 CCC71282.1 - 0.028 14.5 0.1 0.048 13.7 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CCC71282.1 - 0.064 13.5 0.5 0.18 12.1 0.1 2.0 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 CCC71282.1 - 0.082 12.7 0.5 0.2 11.4 0.5 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_5 PF14634.6 CCC71282.1 - 0.61 10.1 4.7 0.15 12.0 1.0 2.0 2 0 0 2 2 2 0 zinc-RING finger domain TPP_enzyme_N PF02776.18 CCC71283.1 - 2.4e-42 144.4 0.0 4.3e-42 143.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 CCC71283.1 - 9.8e-25 86.9 0.0 1.7e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 CCC71283.1 - 2.4e-20 72.9 0.2 9e-20 71.0 0.1 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MFS_1 PF07690.16 CCC71284.1 - 3e-28 98.8 5.6 3e-28 98.8 5.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC71284.1 - 3.2e-10 39.5 3.0 3.2e-10 39.5 3.0 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 CCC71284.1 - 0.0038 15.7 0.3 0.0038 15.7 0.3 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF5521 PF17659.1 CCC71284.1 - 0.22 9.3 0.0 0.32 8.8 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5521) E1-E2_ATPase PF00122.20 CCC71284.1 - 4.5 6.8 4.8 3.1 7.3 0.1 2.2 2 0 0 2 2 2 0 E1-E2 ATPase zf-Tim10_DDP PF02953.15 CCC71285.1 - 1.3e-20 72.8 6.5 1.6e-20 72.5 6.5 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Phasin_2 PF09361.10 CCC71285.1 - 0.034 14.4 0.1 0.27 11.5 0.0 1.9 1 1 1 2 2 2 0 Phasin protein Tam41_Mmp37 PF09139.11 CCC71285.1 - 0.074 12.5 0.2 0.081 12.4 0.2 1.0 1 0 0 1 1 1 0 Phosphatidate cytidylyltransferase, mitochondrial OMPdecase PF00215.24 CCC71286.1 - 2.2e-77 259.7 0.0 2.5e-77 259.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Sec7 PF01369.20 CCC71287.1 - 3.4e-67 225.7 0.3 1e-66 224.1 0.2 1.9 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 CCC71287.1 - 1.2e-14 54.5 3.0 1.4e-14 54.3 0.4 2.6 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 CCC71287.1 - 0.00062 19.5 2.0 0.00062 19.5 2.0 3.9 4 0 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF2683 PF10884.8 CCC71287.1 - 0.12 12.7 1.1 0.47 10.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) DUF2235 PF09994.9 CCC71288.1 - 4.4e-78 262.6 0.0 5.6e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Rieske PF00355.26 CCC71289.1 - 1.7e-10 40.7 0.0 2.9e-10 39.9 0.0 1.4 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 CCC71289.1 - 5.5e-09 36.4 1.5 8.9e-09 35.7 0.3 2.0 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Nucleopor_Nup85 PF07575.13 CCC71290.1 - 3.9e-195 649.7 6.7 4.6e-195 649.5 6.7 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin Phos_pyr_kin PF08543.12 CCC71291.1 - 2e-08 33.9 0.0 2.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 CCC71291.1 - 2e-05 24.0 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Aminotran_1_2 PF00155.21 CCC71292.1 - 1.9e-43 149.1 0.0 3.2e-43 148.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 CCC71292.1 - 2.1e-08 33.5 0.0 3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 CCC71292.1 - 3.1e-07 29.3 0.0 4.3e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 CCC71292.1 - 4.7e-07 29.4 0.0 7.1e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 CCC71292.1 - 0.0073 15.1 0.0 0.036 12.8 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.17 CCC71292.1 - 0.012 14.9 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_MocR PF12897.7 CCC71292.1 - 0.1 11.4 0.0 0.33 9.7 0.0 1.7 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase MCM PF00493.23 CCC71294.1 - 1.1e-97 325.5 0.3 1.7e-97 325.0 0.3 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 CCC71294.1 - 1.6e-32 112.0 0.0 3.5e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 CCC71294.1 - 3.1e-24 85.2 1.1 6.3e-24 84.2 1.1 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 CCC71294.1 - 1.8e-07 30.7 0.0 1.8e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 CCC71294.1 - 2.5e-07 31.2 1.2 1.5e-06 28.8 0.2 2.7 2 1 0 2 2 2 1 MCM N-terminal domain ORC6 PF05460.13 CCC71294.1 - 0.00023 20.5 6.4 0.00046 19.6 6.4 1.5 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) AAA_3 PF07726.11 CCC71294.1 - 0.0046 16.8 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 CCC71294.1 - 0.017 14.8 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain PBP1_TM PF14812.6 CCC71294.1 - 1.1 9.7 19.5 0.95 9.9 1.2 4.6 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3589 PF12141.8 CCC71295.1 - 2.3e-93 313.4 1.7 2.1e-90 303.7 1.7 2.4 1 1 0 1 1 1 1 Beta-mannosyltransferases eIF-5a PF01287.20 CCC71296.1 - 7e-29 99.7 0.4 9.7e-29 99.3 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 CCC71296.1 - 0.00053 20.0 0.0 0.00084 19.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Anp1 PF03452.14 CCC71298.1 - 3.4e-113 377.5 0.0 5.9e-113 376.6 0.0 1.4 2 0 0 2 2 2 1 Anp1 UBA PF00627.31 CCC71299.1 - 1.9e-27 94.8 5.1 7.5e-15 54.5 0.5 2.6 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 CCC71299.1 - 1.1e-17 63.6 1.0 2.6e-17 62.4 0.7 1.8 2 0 0 2 2 2 1 Ubiquitin family XPC-binding PF09280.11 CCC71299.1 - 1.2e-09 37.7 1.5 2.1e-09 36.9 1.5 1.4 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.8 CCC71299.1 - 1.8e-08 34.1 0.8 4.4e-08 32.9 0.8 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 CCC71299.1 - 2.3e-06 27.9 0.5 4.5e-06 26.9 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 CCC71299.1 - 3.2e-06 27.2 0.2 6.3e-06 26.3 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 CCC71299.1 - 0.00078 20.0 0.1 0.0017 18.9 0.1 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain CUE PF02845.16 CCC71299.1 - 0.017 14.8 0.6 1.7 8.4 0.0 4.2 3 2 1 4 4 4 0 CUE domain UBA_3 PF09288.10 CCC71299.1 - 0.081 12.7 0.0 18 5.2 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF1421 PF07223.11 CCC71299.1 - 0.088 12.7 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain (DUF1421) UBA_2 PF08587.11 CCC71299.1 - 0.15 12.2 0.2 0.56 10.4 0.1 2.0 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) TFIIA PF03153.13 CCC71299.1 - 0.56 10.1 8.0 0.75 9.7 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DLIC PF05783.11 CCC71299.1 - 0.73 8.6 3.5 1.1 8.0 3.5 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Mucin PF01456.17 CCC71299.1 - 4 7.4 32.5 2.5 8.1 21.2 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein INO80_Ies4 PF08193.11 CCC71299.1 - 7.5 6.5 14.2 0.39 10.7 7.3 1.9 2 0 0 2 2 2 0 INO80 complex subunit Ies4 SLD3 PF08639.10 CCC71300.1 - 0.064 12.0 0.1 0.09 11.5 0.1 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 Cytochrom_C PF00034.21 CCC71301.1 - 3.1e-11 44.2 0.2 5.7e-11 43.4 0.2 1.4 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 CCC71301.1 - 8.2e-08 32.5 1.8 8.8e-07 29.2 1.8 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 CCC71301.1 - 0.061 13.0 0.3 0.37 10.5 0.1 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain Glyco_hydro_16 PF00722.21 CCC71302.1 - 6.8e-46 156.0 4.8 6.8e-46 156.0 4.8 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Methylase_S PF01420.19 CCC71302.1 - 0.014 15.6 1.3 0.022 15.0 0.3 1.8 2 0 0 2 2 2 0 Type I restriction modification DNA specificity domain Plasmodium_Vir PF05795.11 CCC71302.1 - 0.081 12.3 7.5 0.13 11.6 7.5 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein YcgR_2 PF12945.7 CCC71302.1 - 0.095 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Flagellar protein YcgR NPR3 PF03666.13 CCC71302.1 - 0.17 10.6 4.2 0.29 9.9 4.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Chitin_bind_1 PF00187.19 CCC71302.1 - 0.57 10.7 13.8 1.2 9.7 13.8 1.5 1 0 0 1 1 1 0 Chitin recognition protein SPX PF03105.19 CCC71302.1 - 1.1 9.1 10.8 1.4 8.8 10.8 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 CCC71302.1 - 2 7.2 18.9 2.6 6.8 18.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF1180 PF06679.12 CCC71302.1 - 4.9 7.5 6.1 10 6.5 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Macoilin PF09726.9 CCC71302.1 - 6.6 5.2 21.0 9 4.7 21.0 1.1 1 0 0 1 1 1 0 Macoilin family NAD_kinase PF01513.21 CCC71303.1 - 7.5e-89 297.8 0.0 1.1e-88 297.3 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Collectrin PF16959.5 CCC71303.1 - 0.1 12.4 0.1 0.27 11.0 0.1 1.6 1 0 0 1 1 1 0 Renal amino acid transporter CAF1A PF12253.8 CCC71303.1 - 0.2 11.9 5.2 0.41 10.9 5.2 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A GDA1_CD39 PF01150.17 CCC71304.1 - 1.5e-126 422.6 0.0 1.9e-126 422.2 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family YL1_C PF08265.11 CCC71306.1 - 6.4e-13 48.2 0.2 1.2e-12 47.3 0.2 1.5 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF2075 PF09848.9 CCC71306.1 - 0.074 12.3 0.2 0.094 11.9 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) FAD_binding_2 PF00890.24 CCC71307.1 - 8.1e-73 245.9 0.0 9.6e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 CCC71307.1 - 2e-08 34.3 3.6 3.6e-07 30.1 0.5 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 CCC71307.1 - 1.8e-06 27.4 4.2 2.2e-05 23.9 2.5 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 CCC71307.1 - 3.1e-06 26.6 1.0 0.0016 17.7 0.1 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.6 CCC71307.1 - 1.6e-05 25.1 0.1 0.00012 22.2 0.1 2.4 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 CCC71307.1 - 0.0047 16.0 0.0 0.046 12.8 0.1 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein MCRA PF06100.11 CCC71307.1 - 0.0052 15.6 0.3 1.9 7.2 0.0 2.1 2 0 0 2 2 2 2 MCRA family NAD_binding_9 PF13454.6 CCC71307.1 - 0.0074 16.3 0.1 0.74 9.8 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 CCC71307.1 - 0.011 15.1 0.2 0.14 11.3 0.2 2.1 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 CCC71307.1 - 0.012 15.0 1.0 0.073 12.4 1.0 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 CCC71307.1 - 0.012 14.9 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GMC_oxred_N PF00732.19 CCC71307.1 - 0.029 13.8 1.0 0.42 9.9 0.0 2.6 3 0 0 3 3 3 0 GMC oxidoreductase Pyr_redox PF00070.27 CCC71307.1 - 0.062 13.9 0.7 8.1 7.1 0.1 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 CCC71307.1 - 0.078 11.7 4.5 1.4 7.5 0.4 2.9 3 0 0 3 3 3 0 HI0933-like protein DnaA_N PF11638.8 CCC71307.1 - 0.11 12.3 0.1 9.5 6.1 0.0 3.0 3 0 0 3 3 3 0 DnaA N-terminal domain PilZ PF07238.14 CCC71307.1 - 0.13 12.6 0.0 0.48 10.8 0.0 2.0 2 0 0 2 2 1 0 PilZ domain Sedlin_N PF04628.13 CCC71308.1 - 5.9e-08 32.9 0.5 7.1e-08 32.6 0.5 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region KCH PF16944.5 CCC71310.1 - 1.2e-90 303.7 19.6 1.5e-90 303.4 19.6 1.1 1 0 0 1 1 1 1 Fungal potassium channel Ribosomal_L27_C PF18471.1 CCC71311.1 - 8e-89 297.2 21.9 9.7e-89 296.9 21.9 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein C-terminal domain Ribosomal_L27 PF01016.19 CCC71311.1 - 3.7e-31 107.0 0.0 6.3e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Dimer_Tnp_hAT PF05699.14 CCC71312.1 - 1.2e-06 28.3 0.1 3.3e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.15 CCC71314.1 - 0.11 12.6 0.5 0.27 11.3 0.5 1.8 1 0 0 1 1 1 0 BED zinc finger RRM_1 PF00076.22 CCC71315.1 - 9.1e-63 208.0 0.0 2.3e-20 72.2 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CCC71315.1 - 0.0027 17.7 0.0 11 6.1 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_Rrp7 PF17799.1 CCC71315.1 - 0.039 13.8 0.0 7.7 6.3 0.0 3.3 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Mito_carr PF00153.27 CCC71316.1 - 3.3e-43 145.5 2.0 5.7e-14 51.8 0.0 4.1 3 1 1 4 4 4 4 Mitochondrial carrier protein PUL PF08324.11 CCC71317.1 - 1.4e-44 152.4 1.1 2.1e-44 151.9 1.1 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 CCC71317.1 - 7.9e-41 138.9 0.2 2e-40 137.6 0.2 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 CCC71317.1 - 2e-29 101.2 20.8 1.6e-06 28.7 0.0 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.6 CCC71317.1 - 0.0014 18.6 2.3 1.8 8.7 0.2 3.5 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 CCC71317.1 - 0.0041 16.5 3.1 0.065 12.5 1.8 2.5 1 1 1 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 CCC71317.1 - 0.011 16.1 0.7 20 5.5 0.0 3.8 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain VCBS PF13517.6 CCC71317.1 - 0.037 14.6 3.0 0.82 10.3 0.1 4.1 5 0 0 5 5 5 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FoP_duplication PF13865.6 CCC71318.1 - 1.5e-06 28.6 6.5 3e-06 27.7 6.5 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_1 PF00076.22 CCC71318.1 - 0.001 18.8 0.0 0.0017 18.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sir1 PF11603.8 CCC71320.1 - 2.5e-36 124.8 0.2 1.1e-35 122.7 0.1 2.1 2 0 0 2 2 2 1 Regulatory protein Sir1 DEAD PF00270.29 CCC71320.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase PTPLA PF04387.14 CCC71320.1 - 0.11 12.2 0.1 0.24 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA DUF276 PF03434.13 CCC71322.1 - 0.0079 15.4 0.3 0.013 14.7 0.3 1.3 1 0 0 1 1 1 1 DUF276 RNA_pol_3_Rpc31 PF11705.8 CCC71323.1 - 0.066 13.5 4.3 6.9 6.8 0.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Topo-VIb_trans PF09239.11 CCC71323.1 - 0.15 11.9 0.0 0.26 11.1 0.0 1.3 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer DUF4659 PF15558.6 CCC71324.1 - 0.027 13.3 2.4 0.036 12.9 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4659) DUF5090 PF17009.5 CCC71324.1 - 0.43 10.5 6.2 0.68 9.9 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5090) Hexapep PF00132.24 CCC71325.1 - 1.7e-13 49.7 16.5 2.3e-09 36.6 4.8 3.5 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 CCC71325.1 - 7.5e-12 44.8 15.3 1.4e-08 34.4 2.8 2.7 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase zf-C2HCIx2C PF10782.9 CCC71325.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger FAD-oxidase_C PF02913.19 CCC71326.1 - 6.1e-52 176.7 0.0 8.1e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 CCC71326.1 - 1.2e-34 119.0 0.0 2.1e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NBP1 PF08537.10 CCC71327.1 - 1.2e-94 317.5 28.8 1.4e-94 317.4 28.8 1.0 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 Putative_PNPOx PF01243.20 CCC71328.1 - 2.1e-16 59.9 0.0 5.3e-15 55.4 0.0 2.5 2 1 1 3 3 3 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.7 CCC71328.1 - 0.00028 20.9 0.0 0.0034 17.4 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 CCC71328.1 - 0.00046 19.8 0.3 0.011 15.3 0.1 2.3 1 1 1 2 2 2 1 Pyridoxamine 5'-phosphate oxidase like AvrB_AvrC PF05394.11 CCC71328.1 - 0.025 13.8 0.2 0.032 13.4 0.2 1.1 1 0 0 1 1 1 0 Avirulence protein Cu_bind_CorA PF18252.1 CCC71328.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Copper(I)-binding protein CorA PWWP PF00855.17 CCC71329.1 - 2.3e-17 63.2 0.1 6.1e-17 61.8 0.1 1.8 1 0 0 1 1 1 1 PWWP domain Spt5_N PF11942.8 CCC71329.1 - 1.7 9.7 12.9 0.18 12.8 1.4 2.7 2 1 1 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal ABC_membrane PF00664.23 CCC71330.1 - 0.014 15.0 0.4 0.017 14.8 0.4 1.0 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF4131 PF13567.6 CCC71330.1 - 0.093 12.4 0.2 0.11 12.2 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Med10 PF09748.9 CCC71331.1 - 1.7e-38 131.3 0.1 2e-38 131.0 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Ras PF00071.22 CCC71332.1 - 3e-55 186.2 0.0 4e-55 185.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC71332.1 - 2.9e-21 75.9 0.0 5.3e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC71332.1 - 1e-06 28.3 0.0 1.6e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 CCC71332.1 - 0.064 12.6 0.0 0.084 12.2 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.10 CCC71332.1 - 0.074 12.5 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Fmp27_WPPW PF10359.9 CCC71333.1 - 1.9e-119 399.7 9.1 4.2e-119 398.5 9.1 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27 PF10344.9 CCC71333.1 - 2.7e-109 366.6 50.1 6.1e-109 365.5 50.1 1.6 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.9 CCC71333.1 - 2.5e-72 244.3 10.1 2.4e-48 165.2 4.0 2.6 1 1 1 2 2 2 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 CCC71333.1 - 2.6e-57 193.3 0.2 7.6e-57 191.8 0.2 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.9 CCC71333.1 - 7.4e-52 175.4 2.4 7.4e-52 175.4 2.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.9 CCC71333.1 - 2.3e-31 108.5 0.7 2.4e-30 105.3 0.0 3.2 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain RRM_1 PF00076.22 CCC71334.1 - 7.7e-05 22.4 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TEX19 PF15553.6 CCC71334.1 - 2.9 7.8 0.0 2.9 7.8 0.0 2.8 2 1 1 3 3 3 0 Testis-expressed protein 19 DUF2559 PF10832.8 CCC71334.1 - 6.2 7.0 12.3 58 3.9 0.1 5.4 4 1 2 6 6 6 0 Protein of unknown function (DUF2559) RGS PF00615.19 CCC71336.1 - 1.1e-16 61.2 1.1 4.3e-12 46.3 0.2 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.21 CCC71336.1 - 3.2e-09 36.7 0.0 6.7e-08 32.5 0.0 2.5 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) LRRC37AB_C PF14914.6 CCC71336.1 - 0.068 13.1 1.1 1.5 8.7 0.0 2.7 2 1 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain Zn_clus PF00172.18 CCC71337.1 - 2.4e-08 34.0 10.4 5e-08 32.9 10.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2054 PF10218.9 CCC71337.1 - 0.048 13.8 6.4 0.1 12.7 6.4 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2054) GED PF02212.18 CCC71337.1 - 0.11 12.6 1.3 0.38 10.9 1.3 1.9 1 0 0 1 1 1 0 Dynamin GTPase effector domain WRNPLPNID PF15017.6 CCC71337.1 - 0.11 13.3 1.4 33 5.4 0.7 3.3 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box YvrJ PF12841.7 CCC71337.1 - 0.71 9.4 3.2 2.2 7.9 0.2 2.7 2 0 0 2 2 2 0 YvrJ protein family MFS_1 PF07690.16 CCC71338.1 - 7.8e-27 94.1 34.9 2.4e-19 69.5 16.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 CCC71338.1 - 2e-05 23.6 11.6 0.0003 19.8 11.5 2.4 1 1 0 1 1 1 1 MFS_1 like family MFS_2 PF13347.6 CCC71338.1 - 5.9e-05 21.8 28.8 0.00028 19.6 2.8 3.5 2 2 2 4 4 4 3 MFS/sugar transport protein OATP PF03137.20 CCC71338.1 - 0.00012 20.5 1.7 0.00012 20.5 1.7 2.7 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 CCC71338.1 - 0.01 14.7 20.4 0.15 10.9 20.2 2.8 1 1 0 1 1 1 0 Sugar (and other) transporter Ribosomal_S7 PF00177.21 CCC71339.1 - 3.7e-37 127.2 2.5 5.5e-37 126.7 2.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e GCV_T PF01571.21 CCC71340.1 - 0.0097 15.3 0.0 2.1 7.6 0.0 2.9 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain AGA2 PF17366.2 CCC71340.1 - 0.016 14.9 1.9 0.039 13.7 1.9 1.6 1 0 0 1 1 1 0 A-agglutinin-binding subunit Aga2 ATP-synt_ab PF00006.25 CCC71341.1 - 1.4e-62 211.2 0.0 2.3e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CCC71341.1 - 9e-23 80.6 1.7 2.6e-22 79.1 1.7 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATPase PF06745.13 CCC71341.1 - 0.0012 18.2 0.2 0.002 17.5 0.2 1.4 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.22 CCC71341.1 - 0.0085 15.3 0.7 0.076 12.2 0.1 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA PF00004.29 CCC71341.1 - 0.018 15.5 0.1 0.37 11.2 0.0 2.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) T3SS_ATPase_C PF18269.1 CCC71341.1 - 0.026 14.4 0.5 0.17 11.8 0.5 2.2 1 1 0 1 1 1 0 T3SS EscN ATPase C-terminal domain NACHT PF05729.12 CCC71341.1 - 0.034 14.1 0.1 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 NACHT domain RsgA_GTPase PF03193.16 CCC71341.1 - 0.037 13.9 0.1 0.081 12.8 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase RNA_helicase PF00910.22 CCC71341.1 - 0.086 13.2 0.0 0.22 11.9 0.0 1.7 2 0 0 2 2 1 0 RNA helicase AAA_16 PF13191.6 CCC71341.1 - 0.1 13.0 0.2 0.38 11.1 0.2 2.1 1 1 0 1 1 1 0 AAA ATPase domain RnfC_N PF13375.6 CCC71341.1 - 0.13 12.2 0.2 0.49 10.4 0.1 2.1 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain AAA_19 PF13245.6 CCC71341.1 - 0.14 12.5 0.9 0.48 10.8 0.2 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 CCC71341.1 - 0.18 11.8 0.1 0.47 10.5 0.1 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE JmjC PF02373.22 CCC71342.1 - 1.9e-36 124.9 1.6 4.7e-36 123.7 1.6 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 CCC71342.1 - 6.3e-10 38.8 0.0 1.8e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 jmjN domain PHD PF00628.29 CCC71342.1 - 0.00052 19.9 8.7 0.00052 19.9 8.7 2.5 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 CCC71342.1 - 0.0053 16.6 7.6 0.0053 16.6 7.6 2.8 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.6 CCC71342.1 - 0.022 15.0 7.4 0.068 13.4 4.7 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 CCC71342.1 - 0.058 13.6 4.2 0.17 12.1 4.2 1.7 1 0 0 1 1 1 0 PHD-zinc-finger like domain Zf_RING PF16744.5 CCC71342.1 - 0.075 13.2 5.9 0.2 11.8 5.9 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger Mating_N PF12731.7 CCC71342.1 - 0.12 12.4 0.2 6.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Mating-type protein beta 1 FYVE PF01363.21 CCC71342.1 - 0.13 12.5 9.4 0.14 12.3 6.3 2.3 2 0 0 2 2 2 0 FYVE zinc finger Evr1_Alr PF04777.13 CCC71342.1 - 0.18 12.3 4.1 0.34 11.4 1.3 2.5 2 0 0 2 2 2 0 Erv1 / Alr family PHD_4 PF16866.5 CCC71342.1 - 0.25 11.5 14.9 0.052 13.7 8.1 2.9 2 1 0 2 2 2 0 PHD-finger zf-RING_7 PF02591.15 CCC71342.1 - 0.49 10.6 4.0 30 4.9 0.1 3.5 3 0 0 3 3 3 0 C4-type zinc ribbon domain Ilm1 PF10311.9 CCC71343.1 - 3.2e-13 49.7 12.6 1.2e-10 41.3 12.6 2.1 1 1 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 Rpn3_C PF08375.11 CCC71344.1 - 6.1e-22 77.8 1.8 1.3e-21 76.8 1.8 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.27 CCC71344.1 - 2.9e-19 69.5 0.4 1.2e-18 67.6 0.4 2.1 1 0 0 1 1 1 1 PCI domain Peptidase_M48_N PF16491.5 CCC71345.1 - 5.9e-57 192.5 10.5 5.9e-57 192.5 10.5 2.3 2 1 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 CCC71345.1 - 5.7e-42 143.7 0.1 1.2e-41 142.7 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 CCC71345.1 - 0.0021 17.3 1.1 0.0035 16.6 1.1 1.3 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2268 PF10026.9 CCC71345.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) TRAM_LAG1_CLN8 PF03798.16 CCC71346.1 - 3.3e-30 105.3 18.2 3.3e-30 105.3 18.2 1.4 2 0 0 2 2 2 1 TLC domain PfkB PF00294.24 CCC71347.1 - 2.4e-75 253.7 2.5 2.9e-75 253.4 2.5 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 CCC71347.1 - 2.8e-05 23.6 0.0 5.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Na_Ca_ex PF01699.24 CCC71348.1 - 1.1e-45 155.3 31.7 2.5e-25 89.2 12.1 2.8 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Lipase_3 PF01764.25 CCC71349.1 - 4.7e-35 120.5 0.0 9.8e-35 119.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 CCC71349.1 - 0.054 12.8 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 CCC71349.1 - 0.076 13.6 0.0 0.11 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 CCC71349.1 - 0.093 12.8 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Cutinase PF01083.22 CCC71349.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.8 CCC71349.1 - 0.13 11.8 0.1 1.1 8.8 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 CCC71349.1 - 0.18 11.5 0.0 0.3 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF5137 PF17220.3 CCC71350.1 - 1.1e-25 90.3 2.6 1.2e-25 90.2 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF5137) CPSase_L_D2 PF02786.17 CCC71351.1 - 1.9e-110 367.4 0.0 5.3e-84 280.9 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 CCC71351.1 - 1.9e-38 131.6 0.0 3.5e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp PF02222.22 CCC71351.1 - 3.8e-18 65.6 0.0 3.7e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.6 CCC71351.1 - 6.3e-15 55.1 0.0 4.4e-07 29.7 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.13 CCC71351.1 - 1.6e-14 53.9 0.1 3.4e-06 26.7 0.1 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 CCC71351.1 - 8.2e-06 25.9 0.0 2.7e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 MGS-like domain RimK PF08443.11 CCC71351.1 - 1.8e-05 24.4 0.1 0.072 12.7 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_5 PF13549.6 CCC71351.1 - 0.00085 18.8 0.0 0.05 13.1 0.1 2.5 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.19 CCC71351.1 - 0.061 13.1 0.0 1.8 8.3 0.0 2.7 2 1 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Yippee-Mis18 PF03226.14 CCC71352.1 - 4e-14 52.7 0.6 5.6e-14 52.2 0.6 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Myotub-related PF06602.14 CCC71353.1 - 6.9e-139 462.7 1.0 9.1e-139 462.3 1.0 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 CCC71353.1 - 0.014 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein-tyrosine phosphatase GRAM PF02893.20 CCC71353.1 - 0.038 13.9 0.5 0.13 12.1 0.1 2.3 2 1 0 2 2 2 0 GRAM domain DSPc PF00782.20 CCC71353.1 - 0.08 12.7 0.5 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain CMD PF02627.20 CCC71354.1 - 4.4e-05 23.5 0.0 0.00012 22.0 0.0 1.7 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Nnf1 PF03980.14 CCC71355.1 - 1.3e-30 106.0 9.8 2.1e-30 105.4 9.8 1.3 1 0 0 1 1 1 1 Nnf1 T3SSipB PF16535.5 CCC71355.1 - 0.0062 17.0 2.4 0.33 11.4 1.6 2.9 1 1 1 2 2 2 1 Type III cell invasion protein SipB GIT_CC PF16559.5 CCC71355.1 - 0.0098 15.7 0.2 0.0098 15.7 0.2 2.6 4 0 0 4 4 4 1 GIT coiled-coil Rho guanine nucleotide exchange factor Apolipoprotein PF01442.18 CCC71355.1 - 0.017 15.0 1.3 0.046 13.6 0.2 2.0 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Connexin40_C PF16791.5 CCC71355.1 - 0.16 13.2 1.4 0.6 11.4 0.1 2.1 1 1 0 2 2 2 0 Connexin 40 C-terminal domain DUF4407 PF14362.6 CCC71355.1 - 0.27 10.5 5.2 0.34 10.2 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) MtrG PF04210.13 CCC71355.1 - 0.33 10.8 1.1 1.9 8.4 0.1 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G SlyX PF04102.12 CCC71355.1 - 1 10.0 6.0 7.5 7.3 0.2 3.3 2 1 1 3 3 3 0 SlyX Ribosomal_S7 PF00177.21 CCC71356.1 - 5.9e-35 120.1 0.1 7.9e-35 119.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e rve PF00665.26 CCC71357.1 - 3e-12 46.8 0.1 8.2e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 CCC71357.1 - 0.011 15.4 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Sod_Cu PF00080.20 CCC71359.1 - 8.8e-47 158.8 2.7 1e-46 158.6 2.7 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) ESCRT-II PF05871.12 CCC71360.1 - 7e-48 162.4 3.7 8.5e-48 162.2 3.7 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Sod_Fe_C PF02777.18 CCC71361.1 - 8e-11 42.0 0.2 5.9e-05 23.2 0.1 2.3 1 1 1 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Scramblase PF03803.15 CCC71362.1 - 5.4e-71 238.4 0.1 6.4e-71 238.2 0.1 1.0 1 0 0 1 1 1 1 Scramblase Peptidase_C12 PF01088.21 CCC71363.1 - 1.5e-45 155.5 0.0 1.7e-45 155.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Methyltransf_34 PF11312.8 CCC71363.1 - 0.048 12.9 0.0 0.074 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase LCAT PF02450.15 CCC71364.1 - 6.3e-07 28.9 0.0 9.2e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.7 CCC71364.1 - 1.8e-06 28.7 0.0 2.8e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.13 CCC71364.1 - 3.8e-06 26.8 0.1 1.9e-05 24.5 0.1 2.2 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 CCC71364.1 - 6.5e-06 25.6 0.0 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 CCC71364.1 - 0.00013 21.7 0.0 0.00027 20.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 CCC71364.1 - 0.0011 18.5 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.13 CCC71364.1 - 0.0019 18.1 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.7 CCC71364.1 - 0.0054 16.5 0.6 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 CCC71364.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.6 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LIDHydrolase PF10230.9 CCC71364.1 - 0.067 12.7 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase zf-CSL PF05207.13 CCC71365.1 - 2.9e-19 68.5 0.3 4.3e-19 68.0 0.3 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 CCC71365.1 - 5e-18 65.0 0.5 8.1e-18 64.3 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain UL42 PF17638.2 CCC71365.1 - 0.073 13.0 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 HCMV UL42 Prim_Zn_Ribbon PF08273.12 CCC71365.1 - 0.91 9.9 4.2 2.5 8.5 4.2 1.8 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Aldo_ket_red PF00248.21 CCC71366.1 - 6.4e-42 143.8 0.2 1.4e-39 136.0 0.2 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family DUF4817 PF16087.5 CCC71366.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain (DUF4817) Mito_carr PF00153.27 CCC71367.1 - 2.9e-72 238.7 1.1 1.7e-23 82.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ysc84 PF04366.12 CCC71367.1 - 0.011 15.4 0.7 0.02 14.6 0.7 1.3 1 0 0 1 1 1 0 Las17-binding protein actin regulator PT-VENN PF04829.13 CCC71367.1 - 1.2 9.2 4.9 12 6.1 0.1 3.3 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif Ribosomal_L37ae PF01780.19 CCC71368.1 - 4e-39 132.6 10.2 4.4e-39 132.4 10.2 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family zf-RING_13 PF17977.1 CCC71368.1 - 0.0018 18.4 4.8 0.0026 17.9 4.8 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Lar_restr_allev PF14354.6 CCC71368.1 - 0.0049 17.2 1.6 0.0071 16.7 1.6 1.2 1 0 0 1 1 1 1 Restriction alleviation protein Lar Rep_fac-A_C PF08646.10 CCC71368.1 - 0.039 13.7 0.9 0.044 13.5 0.9 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain YyzF PF14116.6 CCC71368.1 - 0.58 10.2 0.2 0.58 10.2 0.2 2.0 2 0 0 2 2 2 0 YyzF-like protein Zn_Tnp_IS1595 PF12760.7 CCC71368.1 - 0.63 10.1 5.8 1.2 9.2 5.8 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain CarbpepA_inh PF02977.15 CCC71368.1 - 1.4 8.8 7.1 12 5.7 7.1 2.1 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor zf-C4_ClpX PF06689.13 CCC71368.1 - 2.2 8.2 6.7 14 5.7 6.7 2.3 1 1 0 1 1 1 0 ClpX C4-type zinc finger Fip1 PF05182.13 CCC71370.1 - 1.2e-20 72.7 1.0 2.1e-20 71.9 1.0 1.4 1 0 0 1 1 1 1 Fip1 motif YfhD PF14151.6 CCC71370.1 - 0.45 10.7 2.8 2.5 8.3 2.8 2.3 1 1 0 1 1 1 0 YfhD-like protein PH PF00169.29 CCC71371.1 - 2.4e-08 34.4 0.0 1.8e-07 31.6 0.0 2.7 1 1 0 1 1 1 1 PH domain PUF PF00806.19 CCC71372.1 - 5.5e-27 91.9 1.0 0.0002 20.9 0.0 6.4 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.22 CCC71372.1 - 3.3e-06 26.8 0.0 9.8e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.7 CCC71373.1 - 5.1e-07 29.5 1.6 1.4e-06 28.1 1.6 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 CCC71373.1 - 1.9e-05 24.9 6.4 5.8 7.5 0.2 6.4 3 1 4 7 7 7 4 Leucine Rich repeats (2 copies) F-box PF00646.33 CCC71373.1 - 0.00064 19.5 1.7 0.0027 17.6 1.1 2.5 2 0 0 2 2 2 1 F-box domain Preseq_ALAS PF09029.10 CCC71373.1 - 0.17 12.3 0.3 20 5.7 0.0 2.7 2 1 1 3 3 3 0 5-aminolevulinate synthase presequence BIR PF00653.21 CCC71374.1 - 6.7e-07 29.9 2.6 0.031 14.9 0.2 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Evr1_Alr PF04777.13 CCC71375.1 - 1e-24 86.8 0.4 1.7e-24 86.2 0.4 1.3 1 0 0 1 1 1 1 Erv1 / Alr family G-gamma PF00631.22 CCC71376.1 - 1.9e-25 88.6 0.1 2.5e-25 88.3 0.1 1.2 1 0 0 1 1 1 1 GGL domain ENTH PF01417.20 CCC71377.1 - 1.8e-41 141.1 0.0 3.8e-41 140.0 0.0 1.6 1 0 0 1 1 1 1 ENTH domain EFTUD2 PF16004.5 CCC71377.1 - 0.014 16.0 4.6 0.014 16.0 4.6 3.5 4 0 0 4 4 4 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Sel1 PF08238.12 CCC71378.1 - 1.1e-19 70.4 13.3 2.9e-05 24.6 0.0 8.4 9 0 0 9 9 9 4 Sel1 repeat TPR_7 PF13176.6 CCC71378.1 - 0.018 15.0 6.2 0.69 10.1 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.6 CCC71378.1 - 0.03 15.0 0.6 0.2 12.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 CCC71378.1 - 0.034 14.8 6.8 19 6.2 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 CCC71378.1 - 0.18 12.1 4.1 26 5.4 0.2 4.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Turandot PF07240.11 CCC71378.1 - 0.19 11.7 3.7 9 6.3 0.1 3.4 3 0 0 3 3 3 0 Stress-inducible humoral factor Turandot TPR_11 PF13414.6 CCC71378.1 - 0.41 10.4 3.8 0.83 9.4 1.9 2.8 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 CCC71378.1 - 1.1 9.6 4.5 91 3.4 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Hyphal_reg_CWP PF11765.8 CCC71379.1 - 9.2e-19 67.5 2.9 2.6e-18 66.1 2.9 1.7 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal DUF5114 PF17141.4 CCC71379.1 - 0.069 13.7 7.5 0.71 10.4 0.0 3.8 2 2 1 3 3 3 0 Domain of unknown function (DUF5114) WD40 PF00400.32 CCC71380.1 - 2.7e-21 75.5 17.2 4e-05 24.3 0.3 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC71380.1 - 4e-06 27.1 6.0 0.17 12.2 0.2 4.7 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 CCC71380.1 - 0.044 13.7 6.9 0.19 11.6 6.9 2.1 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term GPS PF01825.21 CCC71380.1 - 0.29 11.7 7.4 1.1 9.9 0.2 3.3 3 0 0 3 3 3 0 GPCR proteolysis site, GPS, motif PNP_UDP_1 PF01048.20 CCC71381.1 - 3.2e-44 150.9 0.0 3.9e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Cyclin_N PF00134.23 CCC71382.1 - 1.1e-43 148.0 0.8 6.2e-43 145.6 0.2 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 CCC71382.1 - 3.6e-31 107.7 0.0 7.4e-31 106.7 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF4498 PF14926.6 CCC71383.1 - 0.0046 16.3 2.2 0.018 14.4 0.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4498) Spectrin PF00435.21 CCC71383.1 - 0.072 13.6 3.7 0.084 13.4 0.9 2.4 2 1 0 2 2 2 0 Spectrin repeat DUF1722 PF08349.11 CCC71383.1 - 0.22 11.8 3.0 0.73 10.1 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1722) FlaC_arch PF05377.11 CCC71383.1 - 0.26 11.7 7.3 1 9.8 0.4 3.5 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Rootletin PF15035.6 CCC71383.1 - 0.35 10.9 8.7 0.05 13.6 3.7 1.9 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Tubulin PF00091.25 CCC71384.1 - 1.3e-63 214.8 0.1 2.7e-63 213.7 0.0 1.6 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCC71384.1 - 2.5e-27 95.5 0.3 4.7e-27 94.7 0.3 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 CCC71384.1 - 8.3e-08 32.6 0.1 1.9e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Glyco_hydro_16 PF00722.21 CCC71385.1 - 2.6e-42 144.3 0.0 3.6e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Cellulase PF00150.18 CCC71386.1 - 8.9e-14 51.6 0.4 5.6e-13 49.0 0.0 2.0 1 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) SNF2_N PF00176.23 CCC71387.1 - 3.9e-51 173.8 0.0 8.7e-51 172.7 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCC71387.1 - 4.5e-17 62.4 0.1 1.7e-16 60.5 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.6 CCC71387.1 - 9.2e-06 25.5 3.6 1.8e-05 24.6 3.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCC71387.1 - 4.7e-05 23.2 1.6 9.9e-05 22.1 1.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 CCC71387.1 - 0.00086 19.3 1.2 0.002 18.1 1.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CCC71387.1 - 0.00099 19.4 1.6 0.0022 18.3 1.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCC71387.1 - 0.0013 18.5 1.0 0.0028 17.5 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCC71387.1 - 0.0054 16.6 5.4 0.011 15.6 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCC71387.1 - 0.015 15.1 1.8 0.034 14.0 1.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 CCC71387.1 - 0.059 13.4 0.0 0.059 13.4 0.0 2.8 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit Zn_clus PF00172.18 CCC71388.1 - 3.3e-09 36.7 8.6 5.4e-09 36.0 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CRIC_ras_sig PF10534.9 CCC71388.1 - 0.05 13.8 0.3 0.59 10.3 0.0 2.6 2 1 0 2 2 2 0 Connector enhancer of kinase suppressor of ras Epimerase PF01370.21 CCC71389.1 - 7.3e-19 68.2 0.0 1.2e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCC71389.1 - 1.7e-09 37.1 0.0 2.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 CCC71389.1 - 2.6e-07 30.1 0.2 6.2e-06 25.6 0.2 2.1 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 CCC71389.1 - 3.1e-07 30.5 0.0 4.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 CCC71389.1 - 5.4e-07 29.3 0.1 7.4e-07 28.9 0.1 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase adh_short PF00106.25 CCC71389.1 - 2e-06 27.4 0.2 3.4e-05 23.4 0.1 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 CCC71389.1 - 9.6e-05 21.6 0.2 0.00029 20.1 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 CCC71389.1 - 0.0015 18.5 0.1 0.003 17.5 0.0 1.5 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 CCC71389.1 - 0.021 14.4 0.1 0.049 13.2 0.1 1.6 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.17 CCC71389.1 - 0.026 13.6 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short_C2 PF13561.6 CCC71389.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase SOGA PF11365.8 CCC71390.1 - 0.069 14.3 9.1 0.063 14.4 7.0 2.0 2 0 0 2 2 2 0 Protein SOGA DUF2203 PF09969.9 CCC71390.1 - 0.33 11.7 4.0 0.9 10.3 4.0 1.8 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) FapA PF03961.13 CCC71390.1 - 1 7.9 9.0 1.7 7.2 9.0 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 CCC71390.1 - 4.5 6.4 7.5 8.9 5.5 7.5 1.4 1 0 0 1 1 1 0 TMPIT-like protein CENP-Q PF13094.6 CCC71390.1 - 6.2 7.0 13.6 0.53 10.5 7.8 2.2 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Ribo_biogen_C PF04034.13 CCC71391.1 - 4.8e-50 168.5 0.0 6.9e-50 168.0 0.0 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 CCC71391.1 - 5e-14 51.8 0.3 8e-14 51.2 0.3 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI RHS_repeat PF05593.14 CCC71391.1 - 0.0067 16.9 0.0 1.3 9.7 0.0 2.7 2 1 0 2 2 2 1 RHS Repeat Dcc1 PF09724.9 CCC71391.1 - 0.19 11.0 3.9 0.29 10.4 3.9 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion protein Dcc1 Spore_III_AB PF09548.10 CCC71391.1 - 0.55 10.3 2.6 4.1 7.5 2.6 2.3 2 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) VPS9 PF02204.18 CCC71392.1 - 1.3e-06 28.6 0.6 5.4e-06 26.6 0.6 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.6 CCC71392.1 - 3.4e-06 27.2 0.1 0.00027 21.2 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 CCC71392.1 - 4.4e-05 24.0 0.1 0.098 13.3 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) SGTA_dimer PF16546.5 CCC71393.1 - 1.5e-23 82.4 2.7 1.5e-23 82.4 2.7 2.2 2 1 0 2 2 2 1 Homodimerisation domain of SGTA TPR_1 PF00515.28 CCC71393.1 - 2.2e-17 62.0 10.8 1.4e-07 31.1 0.9 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 CCC71393.1 - 3.1e-14 51.8 9.3 0.00011 22.1 0.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 CCC71393.1 - 9.6e-08 31.6 14.4 0.00084 19.0 1.8 3.3 1 1 2 3 3 3 2 TPR repeat TPR_8 PF13181.6 CCC71393.1 - 1.2e-07 31.4 14.8 6.8e-05 22.8 1.5 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCC71393.1 - 2.9e-07 30.4 2.3 0.029 14.8 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 CCC71393.1 - 2.2e-06 28.2 2.4 0.00021 21.9 0.4 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 CCC71393.1 - 3.6e-06 26.6 5.4 0.016 15.0 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 CCC71393.1 - 5e-06 26.7 3.5 2.2e-05 24.7 0.8 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCC71393.1 - 5.8e-06 26.7 3.6 7.2e-05 23.2 0.8 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCC71393.1 - 7.6e-05 23.2 0.6 1.1 10.2 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCC71393.1 - 0.00016 21.5 1.6 0.49 10.5 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat BTAD PF03704.17 CCC71393.1 - 0.0047 17.4 0.3 0.015 15.7 0.1 1.9 1 1 1 2 2 2 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 CCC71393.1 - 0.0066 17.0 5.5 0.7 10.7 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 CCC71393.1 - 0.017 14.3 2.5 0.05 12.8 2.5 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat STI1 PF17830.1 CCC71393.1 - 0.034 14.1 17.5 0.39 10.7 6.7 2.8 1 1 1 2 2 2 0 STI1 domain Soc PF16855.5 CCC71393.1 - 0.041 14.4 0.5 0.099 13.2 0.5 1.6 1 0 0 1 1 1 0 Small outer capsid protein FKBP_N PF01346.18 CCC71393.1 - 0.39 11.7 0.2 0.39 11.7 0.2 3.0 2 1 1 3 3 3 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Tim29 PF10171.9 CCC71393.1 - 0.39 10.2 2.0 3.5 7.1 0.1 2.5 2 1 1 3 3 3 0 Translocase of the Inner Mitochondrial membrane 29 Fis1_TPR_C PF14853.6 CCC71393.1 - 0.4 10.8 4.8 6.6 6.9 0.2 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat GerD PF17898.1 CCC71393.1 - 0.82 9.6 10.5 0.55 10.2 6.4 2.7 2 1 0 2 2 2 0 Spore germination GerD central core domain MIT PF04212.18 CCC71393.1 - 0.87 9.7 7.7 11 6.1 2.4 3.6 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Pirin PF02678.16 CCC71394.1 - 4.6e-25 87.7 0.1 8.8e-25 86.8 0.1 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 CCC71394.1 - 1.9e-16 60.3 0.0 4.1e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 CCC71394.1 - 0.0037 17.0 1.7 0.043 13.5 0.7 2.3 2 0 0 2 2 2 1 Cupin domain ATP19 PF11022.8 CCC71394.1 - 0.15 12.5 0.1 0.3 11.5 0.1 1.5 1 0 0 1 1 1 0 ATP synthase subunit K DNA_pol_A_exo1 PF01612.20 CCC71396.1 - 5.3e-45 153.3 0.3 1.5e-44 151.8 0.3 1.8 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 CCC71396.1 - 8.1e-22 77.7 8.0 9.2e-22 77.6 3.4 2.9 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.23 CCC71396.1 - 1.6e-10 40.8 0.0 3.8e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 HRDC domain NPR2 PF06218.11 CCC71397.1 - 1.2e-129 433.0 5.3 2.6e-129 431.8 5.3 1.5 1 1 0 1 1 1 1 Nitrogen permease regulator 2 HTH_23 PF13384.6 CCC71397.1 - 0.082 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain Serglycin PF04360.12 CCC71397.1 - 0.84 9.6 4.3 0.57 10.1 0.4 2.6 3 0 0 3 3 3 0 Serglycin Kinesin PF00225.23 CCC71398.1 - 9.9e-95 317.3 11.3 1.6e-62 211.4 4.6 4.2 3 1 1 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 CCC71398.1 - 1.5e-19 70.4 2.5 3.8e-19 69.1 0.1 3.0 2 0 0 2 2 2 1 Microtubule binding TAF6_C PF07571.13 CCC71398.1 - 0.031 14.6 0.2 0.15 12.4 0.2 2.2 1 0 0 1 1 1 0 TAF6 C-terminal HEAT repeat domain Tweety PF04906.13 CCC71398.1 - 1.8 7.1 16.6 0.84 8.2 0.4 2.9 2 1 0 2 2 2 0 Tweety Cpn60_TCP1 PF00118.24 CCC71399.1 - 3.3e-83 280.0 10.5 1e-82 278.4 10.5 1.6 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_I_TF PF04090.12 CCC71400.1 - 2.2e-65 219.9 0.4 3.9e-65 219.1 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor PLA2_B PF01735.18 CCC71401.1 - 2e-233 775.3 5.8 2.4e-233 775.0 5.8 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 CCC71401.1 - 0.082 13.2 1.7 0.15 12.3 1.7 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain TAF4 PF05236.14 CCC71402.1 - 1.4e-57 195.6 4.2 1.4e-57 195.6 4.2 2.0 2 0 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Histone PF00125.24 CCC71402.1 - 0.028 14.8 0.3 0.028 14.8 0.3 3.3 3 1 0 3 3 3 0 Core histone H2A/H2B/H3/H4 NUFIP1 PF10453.9 CCC71403.1 - 7e-20 70.6 1.5 1.8e-19 69.3 1.5 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) MINDY_DUB PF04424.13 CCC71404.1 - 5.3e-27 94.2 0.6 1.2e-26 93.0 0.6 1.6 1 0 0 1 1 1 1 MINDY deubiquitinase CCDC50_N PF15295.6 CCC71404.1 - 0.00077 19.6 2.5 0.0014 18.8 2.5 1.4 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus EPOP PF15223.6 CCC71404.1 - 0.45 9.8 9.9 0.67 9.3 9.9 1.2 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein RRM_1 PF00076.22 CCC71405.1 - 8e-10 38.4 0.5 1.7e-09 37.3 0.1 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCC71405.1 - 0.0047 16.5 0.0 0.03 13.9 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) COA2 PF17051.5 CCC71406.1 - 1.9e-16 59.9 0.1 2e-16 59.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome C oxidase assembly factor 2 INSIG PF07281.12 CCC71406.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Insulin-induced protein (INSIG) DUP PF00674.18 CCC71407.1 - 9.7e-21 73.8 3.6 9.7e-21 73.8 3.6 1.7 2 0 0 2 2 2 1 DUP family MBOAT PF03062.19 CCC71409.1 - 8.2e-69 232.6 18.3 1.4e-68 231.9 18.3 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family NAD_kinase PF01513.21 CCC71410.1 - 6.7e-54 183.1 0.1 1.2e-53 182.2 0.1 1.5 2 0 0 2 2 2 1 ATP-NAD kinase DAGK_cat PF00781.24 CCC71410.1 - 0.027 14.1 0.0 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain MF_alpha_N PF05436.11 CCC71412.1 - 9.8e-29 99.1 0.1 1.2e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus MF_alpha PF04648.12 CCC71412.1 - 9.8e-07 28.8 1.1 1.7e-06 28.1 1.1 1.4 1 0 0 1 1 1 1 Yeast mating factor alpha hormone Internalin_N PF12354.8 CCC71412.1 - 0.074 13.1 1.4 0.074 13.1 1.4 2.1 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal AMPK1_CBM PF16561.5 CCC71413.1 - 1.3e-06 28.5 0.6 2.8e-06 27.4 0.6 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase LAP1C PF05609.12 CCC71413.1 - 0.39 9.7 10.3 0.49 9.4 10.3 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RRM_1 PF00076.22 CCC71414.1 - 1e-28 98.9 0.4 5.1e-08 32.6 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 CCC71414.1 - 6e-16 58.1 0.0 0.0063 16.4 0.0 4.4 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM_5 PF13893.6 CCC71414.1 - 0.00068 19.2 0.0 0.037 13.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 CCC71414.1 - 0.022 14.7 0.0 2.1 8.4 0.0 2.9 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 CCC71414.1 - 0.027 14.5 0.0 0.44 10.6 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif DUF4523 PF15023.6 CCC71414.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) Nab6_mRNP_bdg PF10567.9 CCC71414.1 - 0.13 11.8 3.3 1.3 8.4 0.2 3.2 2 1 1 3 3 3 0 RNA-recognition motif Ribosomal_L36 PF00444.18 CCC71415.1 - 4e-21 74.9 10.0 5.1e-21 74.6 10.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.17 CCC71415.1 - 0.1 12.4 1.1 0.15 11.9 1.1 1.2 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family WD40 PF00400.32 CCC71416.1 - 1.1e-17 64.0 15.9 6.6e-05 23.6 0.1 9.2 10 0 0 10 10 10 3 WD domain, G-beta repeat CPSF_A PF03178.15 CCC71416.1 - 1.6e-06 27.7 1.1 1.9e-05 24.2 0.0 3.1 4 0 0 4 4 4 1 CPSF A subunit region YmzC PF14157.6 CCC71416.1 - 0.0077 16.3 2.6 12 6.1 0.0 4.3 4 0 0 4 4 4 2 YmzC-like protein TCO89 PF10452.9 CCC71417.1 - 4e-96 323.3 61.3 4e-68 230.9 36.4 2.8 2 1 1 3 3 3 2 TORC1 subunit TCO89 Sec1 PF00995.23 CCC71418.1 - 2.7e-121 406.6 18.3 3.1e-121 406.4 18.3 1.0 1 0 0 1 1 1 1 Sec1 family Occludin_ELL PF07303.13 CCC71418.1 - 0.99 10.2 0.0 0.99 10.2 0.0 3.5 4 1 0 4 4 4 0 Occludin homology domain DUF4897 PF16238.5 CCC71418.1 - 1 9.2 8.4 4.3 7.1 0.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4897) PHD PF00628.29 CCC71419.1 - 1.3e-11 44.1 4.8 2.6e-11 43.2 4.8 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 CCC71419.1 - 0.15 11.6 4.4 0.28 10.8 4.4 1.5 1 0 0 1 1 1 0 PHD-finger Metallophos PF00149.28 CCC71420.1 - 2.1e-37 129.6 0.1 3.3e-37 129.0 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCC71420.1 - 1.3e-15 57.5 0.0 3.7e-15 56.1 0.0 1.8 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 CCC71420.1 - 0.043 14.0 0.0 0.071 13.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Peptidase_A2B PF12384.8 CCC71422.1 - 1.3e-11 44.4 0.1 1.9e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase Retrotrans_gag PF03732.17 CCC71422.1 - 0.00047 20.4 0.0 0.00083 19.6 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_2 PF13696.6 CCC71422.1 - 0.0019 18.0 3.0 0.0044 16.8 3.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 CCC71422.1 - 0.0063 16.5 1.2 0.0063 16.5 1.2 1.7 2 0 0 2 2 2 1 Zinc knuckle Asp_protease_2 PF13650.6 CCC71422.1 - 0.094 13.4 0.0 0.18 12.5 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Homeobox_KN PF05920.11 CCC71423.1 - 1.2e-18 66.7 0.7 1.2e-18 66.7 0.7 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 CCC71423.1 - 3.6e-05 23.5 1.3 3.6e-05 23.5 1.3 2.1 2 0 0 2 2 2 1 Homeodomain Arrestin_N PF00339.29 CCC71424.1 - 0.039 14.0 0.2 0.085 12.9 0.2 1.7 1 1 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain DAHP_synth_1 PF00793.20 CCC71425.1 - 2.2e-108 361.3 0.1 2.7e-108 361.0 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family His_biosynth PF00977.21 CCC71426.1 - 2.8e-47 161.1 0.1 1.2e-46 159.1 0.1 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 CCC71426.1 - 4e-21 75.7 0.0 6.8e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 CCC71426.1 - 1.1e-06 28.4 0.0 2.3e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.19 CCC71426.1 - 2.6e-05 24.2 0.0 0.00032 20.6 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.13 CCC71426.1 - 0.0067 16.2 0.1 1.2 8.9 0.0 2.2 2 0 0 2 2 2 2 Peptidase C26 NMO PF03060.15 CCC71426.1 - 0.025 14.0 0.1 0.18 11.2 0.0 2.0 2 0 0 2 2 2 0 Nitronate monooxygenase ThiG PF05690.14 CCC71426.1 - 0.029 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Dus PF01207.17 CCC71426.1 - 0.1 11.6 0.0 0.22 10.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Bystin PF05291.11 CCC71427.1 - 3e-121 404.2 0.0 4.5e-121 403.6 0.0 1.2 1 0 0 1 1 1 1 Bystin MMR_HSR1 PF01926.23 CCC71428.1 - 1.4e-16 60.6 0.2 9.5e-15 54.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 CCC71428.1 - 1.5e-08 34.3 0.2 9.6e-06 25.2 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 CCC71428.1 - 5.8e-08 32.8 0.2 0.0063 16.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AIG1 PF04548.16 CCC71428.1 - 0.0036 16.7 0.0 0.0073 15.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 CCC71428.1 - 0.0073 16.4 0.4 0.0073 16.4 0.4 3.1 3 1 0 3 3 3 1 Dynamin family WD40 PF00400.32 CCC71429.1 - 0.00066 20.4 8.5 0.99 10.4 0.0 5.2 4 1 1 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC71429.1 - 0.034 14.4 0.0 0.31 11.4 0.0 2.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SNF2_N PF00176.23 CCC71430.1 - 3.5e-75 252.9 1.0 3.5e-75 252.9 1.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain SLIDE PF09111.10 CCC71430.1 - 2.8e-37 127.2 2.0 2.8e-37 127.2 2.0 4.7 5 0 0 5 5 4 1 SLIDE HAND PF09110.11 CCC71430.1 - 5.7e-29 101.1 0.7 5.7e-29 101.1 0.7 4.6 5 0 0 5 5 4 1 HAND Helicase_C PF00271.31 CCC71430.1 - 4.9e-20 71.9 0.0 2.9e-19 69.4 0.0 2.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC71430.1 - 8.8e-10 38.8 0.0 8.8e-10 38.8 0.0 3.7 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 CCC71430.1 - 1.2e-09 37.8 0.1 5.2e-09 35.7 0.1 2.1 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.29 CCC71430.1 - 0.00012 21.9 0.0 0.00034 20.4 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 CCC71430.1 - 0.00025 20.3 0.4 0.00025 20.3 0.4 2.3 3 0 0 3 3 2 1 ERCC3/RAD25/XPB C-terminal helicase DEAD_2 PF06733.15 CCC71430.1 - 0.023 14.3 0.1 0.068 12.8 0.1 1.8 1 0 0 1 1 1 0 DEAD_2 AAA_14 PF13173.6 CCC71430.1 - 0.085 12.9 0.7 0.34 10.9 0.1 2.5 2 0 0 2 2 2 0 AAA domain NYD-SP28_assoc PF14775.6 CCC71430.1 - 4.8 7.4 8.3 0.78 9.9 2.5 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain Glycos_transf_4 PF00953.21 CCC71431.1 - 3.4e-31 108.4 10.0 3.4e-31 108.4 10.0 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 4 DUF3413 PF11893.8 CCC71431.1 - 0.0072 15.5 4.3 0.0072 15.5 4.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3413) HD_3 PF13023.6 CCC71432.1 - 1.4e-35 122.7 0.4 1.8e-35 122.3 0.4 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 CCC71432.1 - 1.6e-10 41.1 0.3 2.1e-10 40.6 0.3 1.2 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 CCC71432.1 - 6.9e-06 26.3 0.1 1.3e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 HD domain Sugar_tr PF00083.24 CCC71433.1 - 5.2e-100 335.4 24.0 6.6e-100 335.1 24.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC71433.1 - 6.1e-29 101.1 24.9 5.4e-23 81.5 4.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCC71433.1 - 1e-07 30.8 16.8 4.4e-05 22.1 4.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_4 PF06779.14 CCC71433.1 - 7e-06 25.6 6.9 7e-06 25.6 6.9 2.1 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB DUF3180 PF11377.8 CCC71433.1 - 0.047 13.8 0.2 0.047 13.8 0.2 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3180) TMEM43 PF07787.12 CCC71433.1 - 0.24 10.7 4.1 2.5 7.4 0.1 2.7 2 0 0 2 2 2 0 Transmembrane protein 43 NADH-u_ox-rdase PF10785.9 CCC71433.1 - 4.4 8.0 5.3 3.3 8.5 0.2 3.3 2 1 1 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Zn_clus PF00172.18 CCC71434.1 - 7.6e-12 45.2 4.4 3.9e-11 42.9 4.4 2.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_bind PF01588.20 CCC71435.1 - 8.7e-28 96.3 0.1 1.6e-27 95.4 0.1 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 CCC71435.1 - 0.034 14.2 0.0 0.069 13.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF1654 PF07867.11 CCC71435.1 - 0.08 12.7 0.1 4.2 7.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1654) Viral_protease PF08715.10 CCC71435.1 - 0.1 11.9 0.3 0.21 10.9 0.0 1.6 2 0 0 2 2 2 0 Papain like viral protease GST_C_6 PF17171.4 CCC71435.1 - 0.1 12.4 0.1 0.21 11.4 0.1 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PAS PF00989.25 CCC71436.1 - 9.4e-16 57.8 0.0 2.3e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.18 CCC71436.1 - 0.00038 20.5 18.3 0.00083 19.4 18.3 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_3 PF08447.12 CCC71436.1 - 0.066 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 PAS fold CpeT PF06206.11 CCC71436.1 - 0.086 12.8 0.1 0.26 11.3 0.1 1.7 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) PAS_9 PF13426.7 CCC71436.1 - 0.087 13.1 0.0 0.53 10.6 0.0 2.3 2 0 0 2 2 2 0 PAS domain TFIIA PF03153.13 CCC71437.1 - 1 9.3 35.4 0.29 11.1 22.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DEAD PF00270.29 CCC71438.1 - 3e-47 160.6 2.5 1.9e-46 158.1 0.0 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC71438.1 - 4.7e-22 78.4 1.2 4.7e-21 75.2 0.1 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC71438.1 - 8.8e-07 29.1 0.0 8.8e-07 29.1 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Fis1_TPR_N PF14852.6 CCC71438.1 - 0.039 13.6 0.5 0.039 13.6 0.5 2.0 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat AAA_22 PF13401.6 CCC71438.1 - 0.042 14.1 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 CCC71438.1 - 0.087 13.3 1.4 1.6 9.2 0.4 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pox_MCEL PF03291.16 CCC71439.1 - 1.3e-104 349.9 0.1 1.6e-104 349.7 0.1 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 CCC71439.1 - 2.4e-10 41.0 0.0 4.6e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC71439.1 - 2.1e-09 38.0 0.1 5.9e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC71439.1 - 1.2e-06 29.1 0.0 2.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC71439.1 - 6.2e-06 26.1 0.0 1.8e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCC71439.1 - 5.4e-05 23.1 0.0 0.00013 21.8 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.17 CCC71439.1 - 0.006 15.8 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 CCC71439.1 - 0.0095 15.4 0.0 0.019 14.4 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MetW PF07021.12 CCC71439.1 - 0.18 11.4 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW TMEM237 PF15383.6 CCC71439.1 - 0.63 9.1 2.4 0.6 9.2 1.3 1.5 2 0 0 2 2 2 0 Transmembrane protein 237 AA_permease PF00324.21 CCC71440.1 - 9e-43 146.6 37.4 1.2e-42 146.1 37.4 1.2 1 0 0 1 1 1 1 Amino acid permease SLC12 PF03522.15 CCC71440.1 - 8.1e-17 61.4 4.0 4.2e-10 39.2 0.1 3.2 3 0 0 3 3 3 3 Solute carrier family 12 DUF4229 PF14012.6 CCC71440.1 - 6.9 6.8 8.4 0.51 10.5 1.5 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) WD40_like PF17005.5 CCC71441.1 - 0.0018 17.7 0.5 3.9 6.7 0.1 3.3 3 0 0 3 3 3 3 WD40-like domain KH_1 PF00013.29 CCC71442.1 - 4.4e-28 96.9 0.0 5.4e-09 35.8 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CCC71442.1 - 8.9e-08 31.8 1.8 0.0079 16.0 0.0 3.7 4 0 0 4 4 4 3 KH domain KH_4 PF13083.6 CCC71442.1 - 0.0019 18.0 0.0 0.32 10.9 0.0 2.5 2 0 0 2 2 2 2 KH domain BCNT PF07572.12 CCC71443.1 - 5.3e-24 84.1 0.4 5.3e-24 84.1 0.4 2.5 3 1 0 3 3 3 1 Bucentaur or craniofacial development DUF5353 PF17304.2 CCC71445.1 - 0.00063 19.4 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF5353) Glyco_hydro_31 PF01055.26 CCC71446.1 - 8.5e-125 417.4 0.1 1.3e-124 416.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 CCC71446.1 - 2.3e-23 82.3 0.2 1.3e-22 79.8 0.1 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 CCC71446.1 - 8e-08 32.4 0.6 9.8e-07 29.0 0.1 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF5110) GIY-YIG PF01541.24 CCC71447.1 - 3.2e-13 49.7 0.1 5.7e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-RING_2 PF13639.6 CCC71447.1 - 5.5 7.4 9.6 0.77 10.1 4.9 2.1 2 0 0 2 2 2 0 Ring finger domain AAA_2 PF07724.14 CCC71448.1 - 1.6e-35 122.8 0.9 3.5e-35 121.6 0.9 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 CCC71448.1 - 2.5e-13 50.6 0.2 5.3e-13 49.5 0.2 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 CCC71448.1 - 1.2e-08 34.9 0.0 4.6e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 CCC71448.1 - 3.2e-07 30.4 0.0 8.8e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 CCC71448.1 - 6.4e-05 23.2 2.8 0.0018 18.6 0.3 3.7 3 1 0 3 3 3 1 AAA domain Mg_chelatase PF01078.21 CCC71448.1 - 0.00015 21.2 0.0 0.012 15.0 0.0 2.5 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 CCC71448.1 - 0.00034 20.4 0.0 0.11 12.2 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_16 PF13191.6 CCC71448.1 - 0.00056 20.3 0.5 0.0021 18.4 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 CCC71448.1 - 0.00076 19.6 0.0 0.0019 18.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain RuvB_N PF05496.12 CCC71448.1 - 0.0019 18.0 0.3 0.0078 16.0 0.1 2.1 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CCC71448.1 - 0.0023 17.7 0.0 0.0085 15.8 0.0 2.0 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 CCC71448.1 - 0.0067 16.2 1.0 0.028 14.2 1.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCC71448.1 - 0.007 16.5 0.2 0.026 14.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 CCC71448.1 - 0.0081 15.3 0.2 0.017 14.2 0.2 1.4 1 0 0 1 1 1 1 MCM P-loop domain AAA_14 PF13173.6 CCC71448.1 - 0.011 15.7 0.4 0.03 14.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 CCC71448.1 - 0.022 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 CCC71448.1 - 0.035 14.0 0.1 0.29 11.0 0.0 2.4 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 CCC71448.1 - 0.037 13.8 0.0 0.094 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.16 CCC71448.1 - 0.047 13.2 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein DEAD PF00270.29 CCC71448.1 - 0.058 13.2 2.6 1.4 8.6 0.0 3.5 3 1 1 4 4 4 0 DEAD/DEAH box helicase ABC_tran PF00005.27 CCC71448.1 - 0.076 13.5 2.2 0.099 13.2 0.1 2.2 2 1 0 2 2 2 0 ABC transporter T2SSE PF00437.20 CCC71448.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.22 CCC71448.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase ResIII PF04851.15 CCC71448.1 - 2.9 7.9 8.0 4.4 7.3 0.0 3.5 3 2 1 4 4 4 0 Type III restriction enzyme, res subunit Methyltransf_11 PF08241.12 CCC71449.1 - 0.01 16.5 0.0 0.056 14.1 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 CCC71449.1 - 0.02 14.7 0.1 0.044 13.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 CCC71449.1 - 0.17 12.6 0.0 1.1 10.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Tyr-DNA_phospho PF06087.12 CCC71450.1 - 3.4e-99 332.6 0.3 4.1e-99 332.4 0.3 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 CCC71450.1 - 0.15 12.0 0.0 0.43 10.5 0.0 1.7 2 0 0 2 2 2 0 PLD-like domain AMP-binding PF00501.28 CCC71451.1 - 7.3e-70 235.7 0.0 9.4e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCC71451.1 - 9.4e-14 52.2 0.3 4.4e-13 50.0 0.1 2.2 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain LSM PF01423.22 CCC71451.1 - 0.16 11.7 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 LSM domain Transket_pyr PF02779.24 CCC71452.1 - 1.2e-47 161.9 0.0 2.8e-47 160.7 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CCC71452.1 - 2e-37 127.8 0.1 3.8e-37 126.9 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Acatn PF13000.7 CCC71453.1 - 6.7e-282 935.9 12.3 7.5e-282 935.7 12.3 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 HUN PF08729.10 CCC71454.1 - 5.4e-09 35.9 0.0 1.8e-08 34.2 0.0 2.0 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Kinetochor_Ybp2 PF08568.10 CCC71455.1 - 1.2e-141 473.3 14.5 1.5e-141 473.0 14.5 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Osmo_CC PF08946.10 CCC71455.1 - 0.047 13.9 2.1 0.23 11.7 0.9 2.6 2 0 0 2 2 2 0 Osmosensory transporter coiled coil APG12 PF04110.13 CCC71456.1 - 3.9e-31 107.3 0.1 5.8e-31 106.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 CPSase_L_D2 PF02786.17 CCC71457.1 - 1.5e-81 272.9 0.1 2.7e-81 272.1 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 CCC71457.1 - 6.1e-67 225.2 0.0 1.3e-66 224.2 0.0 1.6 2 0 0 2 2 1 1 Conserved carboxylase domain Biotin_carb_N PF00289.22 CCC71457.1 - 7.4e-39 132.7 0.0 1.6e-38 131.6 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 CCC71457.1 - 1.4e-31 108.8 0.0 7.8e-31 106.4 0.0 2.2 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.19 CCC71457.1 - 7.2e-28 97.9 0.1 1.5e-27 96.9 0.1 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 CCC71457.1 - 4.3e-19 68.1 4.7 4.3e-19 68.1 4.7 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 CCC71457.1 - 9.2e-09 35.1 0.0 2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 CCC71457.1 - 1.5e-08 34.4 0.0 3.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 CCC71457.1 - 3.6e-07 29.9 4.4 0.0051 16.6 0.4 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 CCC71457.1 - 9.3e-06 25.8 0.0 2.5e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 CCC71457.1 - 0.00015 21.1 0.6 0.032 13.5 0.1 2.7 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 CCC71457.1 - 0.0024 18.6 5.4 1.2 9.9 0.1 3.7 4 0 0 4 4 4 2 HlyD family secretion protein ATPgrasp_ST PF14397.6 CCC71457.1 - 0.0042 16.4 0.0 0.0091 15.3 0.0 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATP-grasp_4 PF13535.6 CCC71457.1 - 0.0066 16.1 0.0 0.015 14.9 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain GCV_H PF01597.19 CCC71457.1 - 0.053 13.4 0.7 0.16 11.8 0.7 1.9 1 0 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.6 CCC71457.1 - 0.067 13.2 2.7 0.61 10.1 1.1 2.7 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain YqfD PF06898.11 CCC71457.1 - 0.25 10.1 2.3 0.45 9.3 0.6 2.0 2 0 0 2 2 2 0 Putative stage IV sporulation protein YqfD CBS PF00571.28 CCC71458.1 - 5.3e-19 68.4 4.1 6e-05 23.4 0.0 5.3 5 0 0 5 5 5 5 CBS domain DUF778 PF05608.12 CCC71458.1 - 0.064 13.6 0.0 4.1 7.7 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF778) NAD_binding_7 PF13241.6 CCC71459.1 - 2.3e-22 79.4 0.0 3.5e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.6 CCC71459.1 - 1.9e-15 56.3 0.1 3.4e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.6 CCC71459.1 - 1.6e-09 37.0 0.2 3.3e-09 36.0 0.2 1.5 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.20 CCC71459.1 - 0.023 14.8 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4003 PF13170.6 CCC71459.1 - 0.089 12.2 0.2 0.14 11.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) DUF2076 PF09849.9 CCC71460.1 - 6.2e-05 23.2 7.8 8e-05 22.8 7.8 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.13 CCC71460.1 - 0.00026 21.0 4.5 0.00037 20.5 4.5 1.2 1 0 0 1 1 1 1 CHCH domain CX9C PF16860.5 CCC71460.1 - 0.16 12.0 2.7 0.25 11.4 2.7 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, HlyIII PF03006.20 CCC71461.1 - 3.7e-56 190.4 19.3 4.4e-56 190.1 19.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.6 CCC71461.1 - 0.12 12.9 0.4 0.91 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Peptidase_M44 PF03410.13 CCC71462.1 - 0.039 12.5 2.6 0.05 12.2 2.6 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox THB PF18362.1 CCC71462.1 - 0.069 12.8 0.2 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Tri-helix bundle domain AAA_lid_5 PF17865.1 CCC71462.1 - 0.084 13.0 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Midasin AAA lid domain HSP70 PF00012.20 CCC71463.1 - 4.8e-75 252.9 3.8 6.5e-74 249.2 1.2 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.13 CCC71463.1 - 7.9e-10 38.0 0.0 1.2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein ApbA PF02558.16 CCC71464.1 - 7.5e-32 110.1 0.0 1.2e-31 109.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.11 CCC71464.1 - 8.7e-30 103.5 0.1 1.4e-29 102.8 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.23 CCC71464.1 - 0.041 13.9 0.0 0.52 10.3 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sir1 PF11603.8 CCC71465.1 - 2.6e-31 108.6 0.1 2.6e-31 108.6 0.1 3.4 3 1 0 3 3 3 1 Regulatory protein Sir1 DUF4715 PF15835.5 CCC71465.1 - 0.042 13.9 0.1 0.15 12.2 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) RNase_P_p30 PF01876.16 CCC71467.1 - 1.1e-70 237.5 0.1 1.3e-70 237.2 0.1 1.1 1 0 0 1 1 1 1 RNase P subunit p30 SRR1 PF07985.12 CCC71467.1 - 0.17 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 SRR1 RNase_PH PF01138.21 CCC71468.1 - 3.3e-19 69.7 0.0 6.6e-19 68.7 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 CCC71468.1 - 1.1e-17 63.8 0.1 2.5e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF5572 PF17733.1 CCC71469.1 - 0.052 13.4 0.1 0.18 11.7 0.1 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5572) CN_hydrolase PF00795.22 CCC71471.1 - 3.3e-46 157.7 0.0 4.5e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 CCC71471.1 - 1.4e-22 80.0 0.0 3.8e-22 78.6 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Oxysterol_BP PF01237.18 CCC71472.1 - 5.1e-103 344.8 2.3 4.8e-102 341.6 2.3 2.2 1 1 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.6 CCC71472.1 - 2.5e-31 107.8 0.5 2.5e-31 107.8 0.5 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.29 CCC71472.1 - 2.6e-06 27.9 0.6 1.2e-05 25.8 0.6 2.3 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 CCC71472.1 - 0.069 13.6 7.8 0.8 10.2 4.6 3.6 2 1 0 2 2 2 0 Pleckstrin homology domain CttA_N PF18244.1 CCC71472.1 - 0.13 12.7 1.3 2.6 8.5 0.8 2.7 2 0 0 2 2 2 0 Cellulose-binding protein CttA N-terminal domain CTP_transf_3 PF02348.19 CCC71472.1 - 2.2 8.1 6.4 3.7 7.4 0.1 2.8 3 0 0 3 3 3 0 Cytidylyltransferase Nop10p PF04135.12 CCC71473.1 - 1.7e-22 79.2 0.5 1.9e-22 79.0 0.5 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family SQHop_cyclase_C PF13243.6 CCC71474.1 - 9.9e-42 143.1 0.1 3.7e-41 141.3 0.0 1.8 2 0 0 2 2 2 1 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 CCC71474.1 - 1.7e-33 116.0 0.0 9.7e-30 103.7 0.0 3.1 2 1 1 3 3 3 2 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 CCC71474.1 - 9.2e-24 82.9 0.5 5.1e-07 29.3 0.0 4.4 4 0 0 4 4 4 3 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 CCC71474.1 - 0.0052 15.9 0.2 0.013 14.5 0.0 1.8 2 0 0 2 2 2 1 A-macroglobulin TED domain Cyclin_N PF00134.23 CCC71475.1 - 2.1e-09 37.2 0.3 5.5e-09 35.8 0.2 1.7 1 1 1 2 2 2 1 Cyclin, N-terminal domain Cyclin PF08613.11 CCC71475.1 - 5.9e-07 30.0 0.4 8.2e-07 29.5 0.4 1.3 1 0 0 1 1 1 1 Cyclin Met_10 PF02475.16 CCC71476.1 - 2.4e-77 259.2 0.2 3.3e-77 258.7 0.2 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.13 CCC71476.1 - 0.00066 19.2 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.16 CCC71476.1 - 0.00095 18.4 0.0 0.0072 15.5 0.0 2.0 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase MethyltransfD12 PF02086.15 CCC71476.1 - 0.0076 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase ECR1_N PF14382.6 CCC71477.1 - 6.1e-17 61.1 0.2 1.1e-16 60.3 0.2 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region KH_6 PF15985.5 CCC71477.1 - 7e-10 39.1 0.1 1.4e-09 38.1 0.1 1.6 1 0 0 1 1 1 1 KH domain TAA-Trp-ring PF15401.6 CCC71477.1 - 0.2 12.1 1.3 0.52 10.8 1.3 1.6 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin DS PF01916.17 CCC71478.1 - 3.2e-133 443.4 0.0 3.7e-133 443.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase MaoC_dehydratas PF01575.19 CCC71479.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 CCC71479.1 - 0.099 12.8 0.0 0.42 10.8 0.0 2.0 2 1 0 2 2 2 0 N-terminal half of MaoC dehydratase BSD PF03909.17 CCC71480.1 - 1e-21 76.6 0.7 9.8e-11 41.5 0.2 3.1 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 CCC71480.1 - 1.5e-19 70.1 0.3 3.4e-19 69.0 0.3 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF5638 PF18688.1 CCC71480.1 - 0.028 14.7 0.8 1.3 9.4 0.1 3.2 2 0 0 2 2 2 0 Family of unknown function (DUF5638) PNPase PF03726.14 CCC71480.1 - 0.094 13.2 0.5 0.51 10.9 0.1 2.5 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF2408 PF10303.9 CCC71480.1 - 0.26 11.9 9.7 0.029 14.9 2.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) SpoIIE PF07228.12 CCC71481.1 - 2.5e-30 105.8 0.0 3.7e-30 105.3 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 CCC71481.1 - 5.3e-09 36.1 1.0 6.6e-07 29.2 0.1 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 CCC71481.1 - 0.0005 19.8 0.3 0.0013 18.4 0.3 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C MIF4G PF02854.19 CCC71482.1 - 6.5e-52 176.3 35.4 2.5e-32 112.3 5.2 3.6 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 CCC71482.1 - 2.5e-30 105.9 10.8 2.5e-30 105.9 10.8 2.8 2 1 0 2 2 2 1 Up-frameshift suppressor 2 SDA1 PF05285.12 CCC71482.1 - 1.8 7.9 32.4 0.28 10.6 27.4 2.1 2 0 0 2 2 2 0 SDA1 Nop14 PF04147.12 CCC71482.1 - 2.7 6.1 35.7 0.56 8.3 31.1 2.1 2 0 0 2 2 2 0 Nop14-like family SpoIIIAH PF12685.7 CCC71482.1 - 3.6 7.3 19.3 1.3 8.9 15.4 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein ABA_GPCR PF12430.8 CCC71483.1 - 5.9e-65 218.4 6.3 5.9e-65 218.4 6.3 2.8 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 CCC71483.1 - 3.4e-15 55.9 0.1 1.1e-14 54.3 0.1 1.9 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Pkinase PF00069.25 CCC71484.1 - 1.5e-44 152.4 0.0 5.2e-32 111.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Ribonuc_2-5A PF06479.12 CCC71484.1 - 1.7e-40 138.2 0.2 5.1e-40 136.6 0.2 1.9 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 CCC71484.1 - 5.2e-20 71.8 0.0 1.2e-18 67.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC71484.1 - 0.00041 19.3 2.8 0.0015 17.4 0.1 2.2 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 CCC71484.1 - 0.0026 17.1 0.1 0.0048 16.3 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PQQ_2 PF13360.6 CCC71484.1 - 0.01 15.4 0.0 0.094 12.3 0.0 2.1 1 1 1 2 2 2 0 PQQ-like domain PQQ PF01011.21 CCC71484.1 - 0.036 14.0 0.3 14 5.8 0.0 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat PepSY PF03413.19 CCC71484.1 - 0.15 12.7 1.5 1.6 9.4 0.1 2.8 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain Swi5 PF07061.11 CCC71485.1 - 3.9e-21 74.9 3.6 4.7e-21 74.7 3.6 1.2 1 0 0 1 1 1 1 Swi5 Spc24 PF08286.11 CCC71485.1 - 0.068 13.4 2.0 0.077 13.2 2.0 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Kri1 PF05178.12 CCC71485.1 - 0.57 10.8 6.4 0.37 11.4 4.8 1.5 2 0 0 2 2 2 0 KRI1-like family VASt PF16016.5 CCC71486.1 - 1.3e-69 233.5 12.3 4.2e-36 124.7 0.2 3.4 3 0 0 3 3 3 2 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CCC71486.1 - 2.1e-25 88.8 1.2 5.1e-25 87.6 0.2 2.3 2 0 0 2 2 2 1 GRAM domain Sas10_Utp3 PF04000.15 CCC71487.1 - 2.9e-09 37.4 0.5 2.9e-09 37.4 0.5 2.0 2 1 0 2 2 2 1 Sas10/Utp3/C1D family Use1 PF09753.9 CCC71487.1 - 0.026 14.2 6.1 0.03 14.0 4.0 1.8 1 1 0 2 2 2 0 Membrane fusion protein Use1 GlutR_dimer PF00745.20 CCC71487.1 - 0.46 11.0 3.6 10 6.7 0.0 2.9 1 1 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain Pkinase PF00069.25 CCC71488.1 - 1.6e-43 149.0 1.1 1.6e-39 135.9 0.4 2.3 1 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71488.1 - 6.7e-23 81.3 0.2 1.9e-22 79.8 0.2 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC71488.1 - 0.0051 16.2 0.0 0.009 15.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like SAM35 PF10806.8 CCC71489.1 - 1.5e-38 131.9 0.6 3.4e-38 130.8 0.6 1.6 1 0 0 1 1 1 1 SAM35, subunit of SAM coomplex GST_C_3 PF14497.6 CCC71489.1 - 0.022 14.9 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CCC71489.1 - 0.048 13.5 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 CCC71489.1 - 0.078 13.2 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain STE PF02200.16 CCC71490.1 - 7.3e-59 197.0 2.3 1.2e-58 196.2 2.3 1.4 1 0 0 1 1 1 1 STE like transcription factor Cwf_Cwc_15 PF04889.12 CCC71490.1 - 0.082 12.6 16.5 0.26 11.0 16.5 1.8 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 CCC71490.1 - 2.6 7.3 14.2 5.2 6.3 14.2 1.4 1 0 0 1 1 1 0 NOA36 protein RRM_1 PF00076.22 CCC71491.1 - 3.3e-44 148.6 0.0 8.7e-16 57.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 CCC71491.1 - 6.6e-05 22.5 0.1 0.0054 16.3 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 CCC71491.1 - 0.00047 20.2 0.2 0.21 11.7 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 CCC71491.1 - 0.026 14.6 0.0 0.066 13.3 0.0 1.6 2 0 0 2 2 2 0 RNA binding motif RRM_occluded PF16842.5 CCC71491.1 - 0.07 13.0 0.0 5.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 CCC71491.1 - 0.082 12.9 0.0 0.31 11.1 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SBDS PF01172.18 CCC71492.1 - 2.2e-09 37.3 0.1 2.6e-09 37.0 0.1 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Brix PF04427.18 CCC71493.1 - 2.1e-25 90.0 0.6 3.9e-25 89.1 0.6 1.4 1 0 0 1 1 1 1 Brix domain Pex19 PF04614.12 CCC71493.1 - 0.013 15.3 5.4 0.019 14.7 5.4 1.3 1 0 0 1 1 1 0 Pex19 protein family Xpo1 PF08389.12 CCC71494.1 - 0.00068 19.7 9.7 0.097 12.7 0.2 3.8 4 0 0 4 4 4 2 Exportin 1-like protein DCB PF16213.5 CCC71494.1 - 0.067 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Gar1 PF04410.14 CCC71495.1 - 5.9e-40 136.6 0.0 7.1e-40 136.3 0.0 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region ING PF12998.7 CCC71496.1 - 1.4e-17 64.1 2.1 2.6e-17 63.3 2.1 1.4 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 CCC71496.1 - 3e-06 27.0 7.8 6.2e-06 26.0 7.8 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 CCC71496.1 - 0.0022 18.2 0.4 0.0065 16.7 0.1 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-C4_Topoisom PF01396.19 CCC71496.1 - 0.63 9.9 7.8 2.8 7.8 0.7 2.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger tRNA-synt_1d PF00750.19 CCC71497.1 - 1.2e-123 412.5 6.6 1.5e-123 412.2 6.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 CCC71497.1 - 8.7e-30 103.3 0.3 1.9e-28 99.0 0.1 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 CCC71497.1 - 1.5e-08 35.1 0.0 4.7e-07 30.3 0.0 2.7 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain BRCA2 PF00634.18 CCC71497.1 - 0.14 11.8 0.7 0.36 10.5 0.7 1.7 1 0 0 1 1 1 0 BRCA2 repeat Sugar_tr PF00083.24 CCC71498.1 - 2.7e-172 573.7 34.6 3.1e-172 573.5 34.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC71498.1 - 7.5e-25 87.6 32.3 2.6e-24 85.8 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CCC71498.1 - 1.6 7.1 8.8 0.23 9.8 4.6 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.24 CCC71499.1 - 1.7e-166 554.6 36.8 2e-166 554.4 36.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC71499.1 - 1.2e-32 113.2 46.1 2.5e-29 102.3 28.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GPHR_N PF12537.8 CCC71499.1 - 9 6.5 8.0 7.6 6.7 0.8 2.8 1 1 1 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Pal1 PF08316.11 CCC71500.1 - 3.7e-26 92.5 0.2 3.7e-26 92.5 0.2 2.0 2 1 0 2 2 2 1 Pal1 cell morphology protein Sec23_trunk PF04811.15 CCC71501.1 - 7.3e-61 205.8 0.1 1.6e-60 204.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 CCC71501.1 - 7.4e-18 64.3 0.3 1.7e-17 63.1 0.3 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 CCC71501.1 - 3.7e-13 50.0 0.0 8.8e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 CCC71501.1 - 9.3e-10 38.4 6.4 1.9e-09 37.4 6.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger VWA_2 PF13519.6 CCC71501.1 - 0.00016 22.3 0.0 0.1 13.3 0.1 3.0 2 0 0 2 2 2 2 von Willebrand factor type A domain Gelsolin PF00626.22 CCC71501.1 - 0.0066 16.3 0.0 0.026 14.4 0.0 2.0 2 0 0 2 2 2 1 Gelsolin repeat PGP_phosphatase PF09419.10 CCC71502.1 - 4e-74 247.8 0.0 4.5e-74 247.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 CCC71502.1 - 1.2e-05 25.3 0.0 2e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 CCC71502.1 - 0.057 13.7 0.0 0.14 12.4 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_L25p PF01386.19 CCC71503.1 - 0.12 12.9 0.1 0.39 11.3 0.0 1.9 2 0 0 2 2 2 0 Ribosomal L25p family Pkinase PF00069.25 CCC71504.1 - 1.3e-71 241.0 0.0 8.8e-71 238.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71504.1 - 2e-52 178.1 0.0 4.1e-52 177.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 CCC71504.1 - 1.3e-06 27.4 0.0 4.2e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 CCC71504.1 - 0.0001 21.7 0.1 0.0017 17.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 CCC71504.1 - 0.12 12.0 0.3 2.3 7.8 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SBE2 PF17076.5 CCC71505.1 - 5e-293 974.4 28.3 2.4e-291 968.8 28.3 2.0 1 1 0 1 1 1 1 SBE2, cell-wall formation MAGUK_N_PEST PF10608.9 CCC71506.1 - 0.66 10.4 5.7 1.1 9.8 5.7 1.3 1 1 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Pyr_redox_2 PF07992.14 CCC71508.1 - 5e-52 177.0 0.1 5.8e-52 176.7 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 CCC71508.1 - 2.3e-20 72.9 0.7 8.7e-18 64.7 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 CCC71508.1 - 1.1e-15 57.7 0.0 3.5e-14 52.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 CCC71508.1 - 7.6e-07 28.5 2.1 0.65 9.0 0.2 4.1 3 2 0 4 4 4 3 Glucose inhibited division protein A NAD_binding_7 PF13241.6 CCC71508.1 - 4.7e-05 23.8 0.0 0.017 15.6 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_8 PF13450.6 CCC71508.1 - 0.00016 21.8 0.0 0.033 14.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 CCC71508.1 - 0.00071 18.9 0.2 0.0045 16.3 0.0 2.3 2 1 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.24 CCC71508.1 - 0.0017 17.5 0.5 1.4 7.9 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain FAD_binding_3 PF01494.19 CCC71508.1 - 0.014 14.7 0.1 2.6 7.2 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain K_oxygenase PF13434.6 CCC71508.1 - 0.02 14.0 0.0 1.6 7.8 0.0 3.1 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 CCC71508.1 - 0.022 14.8 0.1 9.2 6.3 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 CCC71508.1 - 0.03 13.0 0.1 1.9 7.1 0.2 3.2 3 1 1 4 4 4 0 HI0933-like protein DAO PF01266.24 CCC71508.1 - 0.042 13.4 0.8 2 7.9 0.0 2.6 2 2 0 3 3 3 0 FAD dependent oxidoreductase Septin PF00735.18 CCC71509.1 - 6.8e-113 376.6 0.0 1e-112 376.1 0.0 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 CCC71509.1 - 4.2e-06 26.8 0.0 8.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.18 CCC71509.1 - 0.0032 16.9 0.0 0.0068 15.8 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family GTP_EFTU PF00009.27 CCC71509.1 - 0.0037 16.8 1.5 0.34 10.4 0.1 3.1 2 2 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 CCC71509.1 - 0.0051 17.1 0.0 0.014 15.6 0.0 1.9 2 1 0 2 2 1 1 AAA domain RsgA_GTPase PF03193.16 CCC71509.1 - 0.0063 16.4 0.3 0.0063 16.4 0.3 3.2 3 1 0 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 CCC71509.1 - 0.0076 16.7 0.0 0.018 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 CCC71509.1 - 0.012 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF3987 PF13148.6 CCC71509.1 - 0.012 14.6 0.1 0.99 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Pox_A32 PF04665.12 CCC71509.1 - 0.017 14.6 0.1 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein Roc PF08477.13 CCC71509.1 - 0.017 15.4 0.3 0.049 13.8 0.0 1.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 CCC71509.1 - 0.017 14.8 0.3 0.051 13.3 0.3 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 CCC71509.1 - 0.034 14.5 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PGBA_C PF15437.6 CCC71509.1 - 0.078 13.4 3.8 0.2 12.0 3.8 1.7 1 0 0 1 1 1 0 Plasminogen-binding protein pgbA C-terminal SHE3 PF17078.5 CCC71509.1 - 0.082 12.6 4.5 0.15 11.7 4.5 1.3 1 0 0 1 1 1 0 SWI5-dependent HO expression protein 3 Sigma54_activat PF00158.26 CCC71509.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain UPF0449 PF15136.6 CCC71509.1 - 5.8 7.4 7.5 0.86 10.1 1.4 2.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 EMP24_GP25L PF01105.24 CCC71511.1 - 8.6e-47 159.4 3.3 9.9e-47 159.2 3.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 CCC71511.1 - 0.014 15.6 0.1 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 SdrD B-like domain DUF4140 PF13600.6 CCC71511.1 - 0.071 13.6 0.2 0.11 12.9 0.2 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Flavodoxin_2 PF02525.17 CCC71512.1 - 5.7e-52 176.3 0.0 6.6e-52 176.1 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCC71512.1 - 2.5e-11 43.5 0.0 5.6e-11 42.4 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Peptidase_M18 PF02127.15 CCC71513.1 - 4.1e-180 599.2 0.0 4.7e-180 599.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 CCC71513.1 - 4e-09 35.9 0.0 1.2e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase RNA_pol_Rpb1_5 PF04998.17 CCC71514.1 - 1.1e-82 277.5 0.3 1.6e-82 277.0 0.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 CCC71514.1 - 1.3e-80 271.0 0.0 3.8e-80 269.5 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 CCC71514.1 - 5.2e-76 254.5 0.0 1e-75 253.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 CCC71514.1 - 1.4e-38 132.3 0.0 3.5e-38 131.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 CCC71514.1 - 9.1e-31 106.0 0.0 2.4e-30 104.6 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 TLD PF07534.16 CCC71515.1 - 1.6e-31 109.4 0.2 1.5e-30 106.2 0.2 2.2 1 1 1 2 2 2 1 TLD Aldo_ket_red PF00248.21 CCC71516.1 - 4.2e-52 177.2 0.0 6.2e-50 170.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Profilin PF00235.19 CCC71517.1 - 2.1e-44 150.9 0.0 2.3e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Profilin DUF3708 PF12501.8 CCC71517.1 - 0.057 13.2 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter Leo1 PF04004.13 CCC71518.1 - 2e-46 157.9 0.1 2e-46 157.9 0.1 2.6 2 0 0 2 2 2 1 Leo1-like protein GPP34 PF05719.11 CCC71519.1 - 1.6e-37 129.6 0.0 2.1e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) UCH PF00443.29 CCC71520.1 - 7.7e-57 192.7 6.0 1.5e-56 191.8 2.1 2.6 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.6 CCC71520.1 - 3.4e-41 139.0 4.7 2e-16 59.6 0.2 4.8 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.6 CCC71520.1 - 0.013 15.1 9.7 0.37 10.3 9.7 2.6 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase COQ7 PF03232.13 CCC71521.1 - 6.1e-73 244.2 0.1 7.7e-73 243.9 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 BCS1_N PF08740.11 CCC71522.1 - 4.9e-47 160.3 0.1 7.3e-47 159.8 0.1 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 CCC71522.1 - 6e-23 81.7 0.0 1.1e-22 80.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 CCC71522.1 - 0.00087 19.1 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 CCC71522.1 - 0.0025 17.4 0.0 0.0072 15.9 0.0 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region DUF815 PF05673.13 CCC71522.1 - 0.0029 16.8 0.0 0.0051 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 CCC71522.1 - 0.0032 17.5 0.0 0.017 15.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 CCC71522.1 - 0.0039 17.6 0.0 0.023 15.1 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_33 PF13671.6 CCC71522.1 - 0.0052 17.0 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 CCC71522.1 - 0.0083 15.9 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 CCC71522.1 - 0.018 15.0 0.0 0.94 9.4 0.0 3.1 2 1 1 3 3 3 0 NACHT domain ABC_tran PF00005.27 CCC71522.1 - 0.019 15.5 0.0 0.046 14.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 CCC71522.1 - 0.027 14.2 0.0 0.065 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 CCC71522.1 - 0.048 14.1 0.0 0.19 12.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 CCC71522.1 - 0.054 13.4 0.0 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea ATPase PF06745.13 CCC71522.1 - 0.059 12.7 0.0 0.13 11.5 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.6 CCC71522.1 - 0.064 13.8 0.0 0.2 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_21 PF13304.6 CCC71522.1 - 0.072 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 CCC71522.1 - 0.095 13.0 0.0 0.28 11.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_11 PF13086.6 CCC71522.1 - 0.095 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gram_pos_anchor PF00746.21 CCC71522.1 - 0.32 11.0 1.2 0.63 10.0 1.2 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Lipase_GDSL_2 PF13472.6 CCC71523.1 - 1.8e-24 87.1 0.0 2.2e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 CCC71523.1 - 1.4e-14 54.5 0.0 5.8e-14 52.5 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RhoGAP PF00620.27 CCC71524.1 - 1.7e-41 141.5 0.5 5.2e-41 140.0 0.5 1.8 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.22 CCC71524.1 - 1.1e-12 48.0 29.1 2e-06 27.9 8.0 2.6 2 0 0 2 2 2 2 LIM domain KASH_CCD PF14662.6 CCC71524.1 - 0.0028 17.5 4.9 0.0028 17.5 4.9 1.8 2 0 0 2 2 2 1 Coiled-coil region of CCDC155 or KASH CHASE7 PF17151.4 CCC71524.1 - 0.01 15.4 0.1 0.02 14.5 0.1 1.3 1 0 0 1 1 1 0 Periplasmic sensor domain AIRC PF00731.20 CCC71525.1 - 4.2e-61 204.9 0.4 7e-61 204.1 0.4 1.3 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 CCC71525.1 - 1.4e-58 197.2 0.0 2.2e-58 196.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 CCC71525.1 - 3.9e-17 61.7 0.0 7.3e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain CPSase_L_D2 PF02786.17 CCC71525.1 - 3.5e-05 23.4 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.19 CCC71525.1 - 0.0025 17.2 0.0 0.0059 16.0 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 CCC71525.1 - 0.0078 15.5 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Dala_Dala_lig_C PF07478.13 CCC71525.1 - 0.039 13.5 0.0 0.14 11.7 0.0 1.9 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus NAD_binding_10 PF13460.6 CCC71525.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Afi1 PF07792.12 CCC71526.1 - 1.7e-28 99.8 0.5 4.6e-28 98.4 0.5 1.8 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.10 CCC71526.1 - 4.4e-26 91.1 0.4 4.4e-26 91.1 0.4 2.7 3 0 0 3 3 3 1 Stabilization of polarity axis AbiTii PF18864.1 CCC71526.1 - 0.16 12.1 2.9 0.41 10.8 0.5 2.6 3 0 0 3 3 3 0 AbiTii Mito_carr PF00153.27 CCC71527.1 - 7.1e-59 195.7 0.2 8e-20 70.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4444 PF14563.6 CCC71527.1 - 0.029 14.0 0.1 0.061 13.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4444) VasI PF11319.8 CCC71527.1 - 0.11 12.2 0.1 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 Type VI secretion system VasI, EvfG, VC_A0118 Ribosomal_60s PF00428.19 CCC71528.1 - 9.5e-24 83.8 10.8 1.1e-23 83.6 10.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein PqqD PF05402.12 CCC71528.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Hyphal_reg_CWP PF11765.8 CCC71530.1 - 1.2e-21 77.0 12.3 1.2e-21 77.0 12.3 2.4 3 0 0 3 3 3 1 Hyphally regulated cell wall protein N-terminal HAD_2 PF13419.6 CCC71531.1 - 9e-18 65.0 0.1 1.9e-16 60.7 0.1 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 CCC71531.1 - 4.5e-15 56.5 0.0 3.7e-10 40.4 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 CCC71531.1 - 6.3e-08 32.6 0.0 2.6e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 CCC71531.1 - 0.011 15.3 0.0 0.86 9.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Hydrolase_3 PF08282.12 CCC71531.1 - 0.018 14.8 0.0 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HAD PF12710.7 CCC71531.1 - 0.072 13.5 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Vps5 PF09325.10 CCC71532.1 - 3.6e-05 23.4 9.3 8.1e-05 22.3 9.3 1.6 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 CCC71532.1 - 0.00085 19.3 1.1 0.0019 18.1 1.1 1.6 1 0 0 1 1 1 1 PX domain IZUMO PF15005.6 CCC71532.1 - 0.26 11.8 2.0 0.93 10.0 0.8 2.6 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated GTP_EFTU PF00009.27 CCC71533.1 - 1.1e-67 227.3 0.3 1.6e-67 226.8 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CCC71533.1 - 3.1e-33 114.1 0.0 2e-32 111.5 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 CCC71533.1 - 1.1e-21 76.6 0.0 3.1e-21 75.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCC71533.1 - 4.4e-14 52.6 0.0 5.5e-13 49.1 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.6 CCC71533.1 - 5e-14 52.1 0.0 2.5e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 CCC71533.1 - 0.00014 21.9 0.1 0.00029 20.9 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RhoGAP PF00620.27 CCC71534.1 - 5.6e-34 117.2 0.4 6.1e-33 113.8 0.4 2.2 1 1 0 1 1 1 1 RhoGAP domain Iso_dh PF00180.20 CCC71535.1 - 4e-103 345.2 0.0 5.2e-103 344.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Metallophos PF00149.28 CCC71536.1 - 1.4e-13 51.9 0.0 2.9e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UBA PF00627.31 CCC71537.1 - 1.1e-08 34.7 0.4 3.2e-08 33.3 0.1 2.0 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.6 CCC71537.1 - 0.034 14.0 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain HSF_DNA-bind PF00447.17 CCC71538.1 - 1.1e-27 96.4 2.7 1.1e-27 96.4 2.7 2.6 3 0 0 3 3 3 1 HSF-type DNA-binding Actin PF00022.19 CCC71539.1 - 2.5e-24 85.6 0.0 9.1e-18 64.0 0.0 3.5 2 1 0 2 2 2 2 Actin Actin_micro PF17003.5 CCC71539.1 - 1.4e-10 40.9 1.4 9.1e-05 21.8 0.1 2.4 2 0 0 2 2 2 2 Putative actin-like family NRho PF16733.5 CCC71539.1 - 0.0045 17.0 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Rhomboid N-terminal domain SDA1 PF05285.12 CCC71539.1 - 0.057 12.8 15.1 0.13 11.7 15.1 1.5 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 CCC71539.1 - 0.19 10.0 8.7 0.32 9.2 8.7 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 CCC71539.1 - 0.45 8.7 19.3 0.96 7.6 19.3 1.5 1 0 0 1 1 1 0 Nop14-like family PPL5 PF18168.1 CCC71539.1 - 1.3 8.2 9.1 27 3.9 0.0 2.5 2 0 0 2 2 2 0 Prim-pol family 5 CoA_binding PF02629.19 CCC71540.1 - 2e-26 92.5 1.5 4e-26 91.5 0.3 1.9 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 CCC71540.1 - 3.1e-23 82.3 0.4 4.9e-23 81.6 0.4 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 CCC71540.1 - 3e-07 30.3 0.0 6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 CCC71540.1 - 0.00022 21.7 0.0 0.0005 20.5 0.0 1.6 2 0 0 2 2 2 1 CoA binding domain TPK_catalytic PF04263.16 CCC71541.1 - 4.8e-31 107.3 0.3 2.4e-30 105.1 0.3 1.9 1 1 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 CCC71541.1 - 3.5e-13 49.1 0.1 7.8e-13 47.9 0.1 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain AAA PF00004.29 CCC71542.1 - 4e-05 24.0 1.3 0.0001 22.7 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 CCC71542.1 - 0.042 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF4533 PF15047.6 CCC71542.1 - 0.045 13.3 2.5 2.3 7.7 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4533) Utp12 PF04003.12 CCC71543.1 - 9e-24 83.8 4.8 2e-23 82.8 4.8 1.6 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 CCC71543.1 - 0.00052 19.4 4.5 0.0016 17.9 4.2 1.7 1 1 1 2 2 2 2 WD40-like domain YabP PF07873.11 CCC71543.1 - 0.027 14.3 0.1 0.076 12.8 0.1 1.7 1 0 0 1 1 1 0 YabP family CBFD_NFYB_HMF PF00808.23 CCC71544.1 - 1.4e-12 47.7 0.4 2.3e-12 47.0 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2960 PF11173.8 CCC71544.1 - 0.073 13.5 0.1 0.13 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2960) Glyco_transf_22 PF03901.17 CCC71545.1 - 1.3e-74 251.9 35.6 1.5e-74 251.7 35.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family G-patch_2 PF12656.7 CCC71546.1 - 2.3e-19 69.2 0.1 2.3e-19 69.2 0.1 2.2 3 0 0 3 3 3 1 G-patch domain DUF4221 PF13970.6 CCC71547.1 - 0.022 14.3 0.1 0.025 14.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4221) MDM31_MDM32 PF08118.11 CCC71548.1 - 8e-61 206.3 20.5 2e-38 132.4 3.9 4.7 1 1 2 4 4 4 4 Yeast mitochondrial distribution and morphology (MDM) proteins Ribosomal_L13 PF00572.18 CCC71549.1 - 2.6e-47 160.2 0.1 3.3e-47 159.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 RNA_pol_Rpb2_6 PF00562.28 CCC71550.1 - 5.1e-127 424.2 0.2 8.3e-127 423.5 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 CCC71550.1 - 2.6e-73 245.9 0.0 4.3e-73 245.1 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 CCC71550.1 - 1.1e-51 175.1 0.0 2.3e-51 174.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 CCC71550.1 - 2.6e-34 117.5 0.1 5.9e-34 116.3 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 CCC71550.1 - 1.6e-25 89.2 0.3 3.6e-25 88.0 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 CCC71550.1 - 2.4e-24 85.3 0.1 6.4e-24 83.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.17 CCC71550.1 - 8.2e-19 67.9 2.7 8.2e-19 67.9 2.7 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 MRNIP PF15749.5 CCC71550.1 - 0.091 13.5 0.1 0.19 12.5 0.1 1.5 1 0 0 1 1 1 0 MRN-interacting protein ABC2_membrane PF01061.24 CCC71552.1 - 4.6e-85 284.3 57.0 1.1e-44 152.4 22.2 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 CCC71552.1 - 8.8e-40 136.4 0.0 1.2e-18 68.0 0.0 3.6 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 CCC71552.1 - 1.9e-33 114.2 8.6 8.6e-30 102.5 0.0 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 CCC71552.1 - 8.5e-19 68.0 0.0 2e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_16 PF13191.6 CCC71552.1 - 2.4e-07 31.3 0.0 4.3e-05 24.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.6 CCC71552.1 - 2.9e-07 30.3 0.0 2.9e-05 23.7 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 CCC71552.1 - 3.4e-06 27.6 0.2 0.0011 19.5 0.0 3.1 3 0 0 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 CCC71552.1 - 1.6e-05 24.9 0.0 0.0015 18.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_3 PF12698.7 CCC71552.1 - 0.00012 21.3 31.1 0.0031 16.7 10.1 2.7 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_29 PF13555.6 CCC71552.1 - 0.00018 21.2 0.4 0.0081 15.9 0.1 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain SMC_N PF02463.19 CCC71552.1 - 0.00031 20.3 0.0 0.0057 16.1 0.0 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 CCC71552.1 - 0.00047 20.1 0.0 0.32 10.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 CCC71552.1 - 0.0017 18.6 0.0 0.059 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.6 CCC71552.1 - 0.0027 18.3 0.0 0.042 14.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 CCC71552.1 - 0.0029 17.5 0.4 3 7.7 0.1 2.7 2 0 0 2 2 2 2 NACHT domain AAA_28 PF13521.6 CCC71552.1 - 0.0039 17.5 1.6 0.27 11.5 0.3 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCC71552.1 - 0.0054 17.0 2.7 0.46 10.8 0.1 3.5 4 0 0 4 4 3 1 AAA domain cobW PF02492.19 CCC71552.1 - 0.0074 15.9 3.3 0.9 9.1 0.5 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain DnaB_C PF03796.15 CCC71552.1 - 0.029 13.7 0.0 0.74 9.1 0.0 2.3 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain AAA_30 PF13604.6 CCC71552.1 - 0.03 14.1 0.4 3.2 7.4 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 CCC71552.1 - 0.038 14.4 0.1 1.6 9.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_13 PF13166.6 CCC71552.1 - 0.12 11.0 1.2 3.2 6.3 0.0 2.9 4 0 0 4 4 4 0 AAA domain NTPase_1 PF03266.15 CCC71552.1 - 0.22 11.4 0.4 22 4.9 0.1 2.9 3 0 0 3 3 3 0 NTPase ISN1 PF06437.11 CCC71553.1 - 4.8e-183 608.7 0.0 5.5e-183 608.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Choline_transpo PF04515.12 CCC71554.1 - 1.5e-75 254.5 21.7 1.5e-75 254.5 21.7 2.2 2 0 0 2 2 2 1 Plasma-membrane choline transporter PAP2 PF01569.21 CCC71554.1 - 1.5 8.6 22.4 0.64 9.8 10.5 4.0 4 0 0 4 4 4 0 PAP2 superfamily Xpo1 PF08389.12 CCC71555.1 - 8.2e-24 84.4 3.2 8.2e-24 84.4 3.2 4.5 5 0 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.19 CCC71555.1 - 3.5e-05 23.6 2.3 0.00028 20.7 0.7 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.22 CCC71555.1 - 0.0014 18.7 0.0 1.7 9.1 0.0 3.2 2 0 0 2 2 2 2 HEAT repeat Dynein_AAA_lid PF17852.1 CCC71555.1 - 0.022 14.9 0.4 7.8 6.6 0.0 3.2 3 0 0 3 3 3 0 Dynein heavy chain AAA lid domain Epsilon_antitox PF08998.11 CCC71555.1 - 0.027 14.8 0.2 0.45 10.8 0.0 2.9 2 0 0 2 2 2 0 Bacterial epsilon antitoxin LSM PF01423.22 CCC71556.1 - 2.1e-15 56.1 0.1 2.5e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 CCC71556.1 - 0.0047 16.6 0.4 0.0089 15.7 0.1 1.6 2 0 0 2 2 2 1 Hfq protein Peptidase_C34 PF05413.11 CCC71556.1 - 0.12 12.6 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase Proteasome PF00227.26 CCC71558.1 - 6e-48 162.9 0.1 8.7e-48 162.3 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.8 CCC71558.1 - 3.4e-14 51.9 0.0 3.4e-14 51.9 0.0 1.6 2 0 0 2 2 2 1 Proteasome beta subunits C terminal PINIT PF14324.6 CCC71559.1 - 8.6e-33 113.7 0.1 2e-32 112.6 0.1 1.7 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.20 CCC71559.1 - 4.5e-22 77.6 7.8 8.2e-22 76.7 7.8 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.27 CCC71559.1 - 3.1e-08 33.2 0.0 5.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.8 CCC71559.1 - 4.2e-05 23.3 0.5 9.4e-05 22.2 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 CCC71559.1 - 0.0028 17.7 1.8 0.0059 16.6 1.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger DUF4840 PF16128.5 CCC71559.1 - 0.078 13.0 1.0 1.5 8.9 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4840) zf-C3HC4_2 PF13923.6 CCC71559.1 - 0.1 12.4 3.8 0.22 11.4 3.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Carn_acyltransf PF00755.20 CCC71560.1 - 2e-178 594.7 0.6 2.3e-178 594.5 0.6 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ribosomal_L2_C PF03947.18 CCC71561.1 - 2.1e-51 173.4 4.4 4.1e-51 172.4 4.4 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 CCC71561.1 - 1.7e-24 85.6 0.5 5.9e-24 83.8 0.1 2.1 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain AFG1_ATPase PF03969.16 CCC71562.1 - 1.1e-74 251.5 0.0 1.2e-69 234.9 0.0 3.0 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 CCC71562.1 - 0.00011 22.6 0.1 0.022 15.2 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.29 CCC71562.1 - 0.00086 19.7 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCC71562.1 - 0.013 15.8 0.1 0.059 13.7 0.1 2.1 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 CCC71562.1 - 0.016 15.2 0.0 0.031 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 CCC71562.1 - 0.017 15.2 0.0 0.054 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 CCC71562.1 - 0.019 14.9 0.0 0.06 13.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 CCC71562.1 - 0.035 14.5 0.0 0.14 12.6 0.0 2.2 1 1 0 1 1 1 0 RNA helicase ABC_tran PF00005.27 CCC71562.1 - 0.077 13.5 0.0 1.1 9.7 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Mak10 PF04112.13 CCC71563.1 - 2.3e-39 134.6 0.0 5.2e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ribosomal_L11_N PF03946.14 CCC71564.1 - 2.4e-21 75.3 1.0 4.7e-21 74.4 0.4 1.7 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 CCC71564.1 - 1.8e-16 60.4 0.9 4.3e-16 59.2 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain PAP1 PF08601.10 CCC71566.1 - 3.7e-19 69.7 0.5 3.7e-19 69.7 0.5 5.0 2 1 2 5 5 5 3 Transcription factor PAP1 bZIP_1 PF00170.21 CCC71566.1 - 1e-05 25.5 13.5 3.2e-05 23.9 13.5 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CCC71566.1 - 0.00031 20.7 8.1 0.00095 19.2 8.1 1.9 1 0 0 1 1 1 1 Basic region leucine zipper Sterol_MT_C PF08498.10 CCC71567.1 - 1.5e-27 95.6 1.0 2.5e-27 94.9 1.0 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.6 CCC71567.1 - 4.2e-20 72.1 0.1 1.2e-19 70.6 0.1 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC71567.1 - 1.5e-19 70.4 0.0 3.9e-19 69.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCC71567.1 - 2.7e-17 63.3 0.0 8.4e-17 61.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.20 CCC71567.1 - 2.6e-13 49.9 0.3 3.6e-13 49.4 0.3 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 CCC71567.1 - 3.4e-12 46.5 0.0 6.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC71567.1 - 4.8e-12 46.5 0.1 2.5e-11 44.2 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 CCC71567.1 - 2.8e-09 36.6 0.0 4.6e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 CCC71567.1 - 0.00026 21.0 0.2 0.00051 20.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 CCC71567.1 - 0.0012 18.4 0.4 0.003 17.2 0.2 1.6 1 1 0 1 1 1 1 RNA cap guanine-N2 methyltransferase PrmA PF06325.13 CCC71567.1 - 0.0038 16.6 0.0 0.023 14.1 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 CCC71567.1 - 0.0049 16.6 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 CCC71567.1 - 0.016 16.2 0.0 0.047 14.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 CCC71567.1 - 0.048 13.2 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 CCC71567.1 - 0.1 12.2 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PX PF00787.24 CCC71568.1 - 1.9e-16 60.1 0.1 1.9e-16 60.1 0.1 2.7 3 0 0 3 3 3 1 PX domain DUF3258 PF11646.8 CCC71568.1 - 0.39 10.9 4.1 0.22 11.7 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function DUF3258 eIF3g PF12353.8 CCC71569.1 - 5.1e-39 133.5 4.8 7.1e-39 133.0 4.8 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.22 CCC71569.1 - 1.5e-12 47.2 0.0 3.3e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 CCC71569.1 - 0.51 10.5 4.7 3.8 7.7 4.7 2.2 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Ribosomal_L33 PF00471.20 CCC71570.1 - 0.0083 16.6 0.0 0.015 15.8 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L33 Spt5-NGN PF03439.13 CCC71571.1 - 1.6e-21 75.9 0.0 5.3e-21 74.3 0.0 1.9 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.29 CCC71571.1 - 6.2e-21 73.6 7.1 3.1e-05 23.8 0.1 4.9 4 0 0 4 4 4 4 KOW motif Spt5_N PF11942.8 CCC71571.1 - 2.7e-20 73.2 10.4 2.7e-20 73.2 10.4 3.0 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 CCC71571.1 - 0.00098 19.3 0.1 0.31 11.3 0.1 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3912) CTD PF12815.7 CCC71571.1 - 0.0019 18.7 27.5 0.0019 18.7 27.5 4.1 3 1 0 3 3 3 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Myosin_N PF02736.19 CCC71571.1 - 0.66 9.8 5.3 0.64 9.9 0.4 3.3 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DUF150_C PF17384.2 CCC71571.1 - 0.88 9.7 4.2 2.3 8.4 0.2 3.0 3 0 0 3 3 3 0 RimP C-terminal SH3 domain Nucleo_P87 PF07267.11 CCC71571.1 - 2.1 7.1 21.5 4.1 6.1 21.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Hamartin PF04388.12 CCC71571.1 - 8.3 4.9 14.3 12 4.4 14.3 1.2 1 0 0 1 1 1 0 Hamartin protein Rad33 PF08730.10 CCC71572.1 - 1e-10 41.9 3.2 4e-05 23.7 0.4 2.1 1 1 1 2 2 2 2 Rad33 TssC PF17541.2 CCC71572.1 - 0.0048 15.8 1.6 0.02 13.7 0.7 1.9 1 1 1 2 2 2 1 Type VI secretion system, TssC, VipB EMP24_GP25L PF01105.24 CCC71573.1 - 1.7e-41 142.2 0.0 2e-41 142.0 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD EzrA PF06160.12 CCC71573.1 - 0.01 14.1 1.1 0.013 13.7 1.1 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Takusan PF04822.13 CCC71573.1 - 0.047 13.6 1.2 0.1 12.5 1.2 1.5 1 0 0 1 1 1 0 Takusan TMEM191C PF15194.6 CCC71573.1 - 0.055 13.6 0.5 0.081 13.1 0.0 1.5 2 0 0 2 2 2 0 TMEM191C family UBA_4 PF14555.6 CCC71574.1 - 5.2e-11 42.2 0.2 1.3e-10 40.9 0.1 1.8 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.20 CCC71574.1 - 6e-11 42.4 0.2 3.3e-09 36.8 0.1 3.2 2 1 0 2 2 2 1 UBX domain MRP-S26 PF14943.6 CCC71574.1 - 0.26 11.2 10.8 11 5.9 8.3 2.5 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 EIIBC-GUT_N PF03612.14 CCC71574.1 - 0.33 10.7 1.7 7.6 6.2 0.8 2.5 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Methyltransf_11 PF08241.12 CCC71575.1 - 5.2e-12 46.2 0.0 9.1e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 CCC71575.1 - 1.1e-09 38.9 0.0 1.8e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 CCC71575.1 - 2.9e-06 27.1 0.1 5.1e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC71575.1 - 7.3e-06 26.7 0.4 2.8e-05 24.8 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCC71575.1 - 0.001 19.0 3.1 0.0061 16.4 3.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain ORC_WH_C PF18137.1 CCC71575.1 - 0.12 12.4 3.9 0.2 11.7 3.9 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Lys-AminoMut_A PF09043.11 CCC71575.1 - 0.13 10.7 0.3 0.18 10.2 0.3 1.1 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase TIM-barrel domain of alpha subunit DUF913 PF06025.12 CCC71575.1 - 0.21 10.5 1.0 0.29 10.0 1.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Metallophos PF00149.28 CCC71576.1 - 5.1e-36 125.1 0.1 1.2e-35 123.8 0.1 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCC71576.1 - 1.6e-16 60.5 0.1 3.2e-16 59.5 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain RRM_1 PF00076.22 CCC71577.1 - 0.11 12.3 0.3 11 6.0 0.0 2.6 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EamA PF00892.20 CCC71578.1 - 4.3e-13 49.6 29.3 8e-08 32.5 1.5 3.3 3 0 0 3 3 3 2 EamA-like transporter family PUNUT PF16913.5 CCC71578.1 - 0.0014 17.9 4.8 0.0014 17.9 4.8 3.3 2 1 1 3 3 3 1 Purine nucleobase transmembrane transport DUF3955 PF13127.6 CCC71578.1 - 0.0016 18.2 5.7 0.0016 18.2 5.7 4.1 6 0 0 6 6 6 1 Protein of unknown function (DUF3955) OST3_OST6 PF04756.13 CCC71579.1 - 1.9e-67 227.7 5.5 2.2e-67 227.5 5.5 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family UDG PF03167.19 CCC71581.1 - 6.6e-23 81.4 0.0 1.1e-22 80.7 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Pribosyltran PF00156.27 CCC71582.1 - 1.7e-17 63.4 0.0 2.3e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 CCC71582.1 - 0.0069 15.8 0.0 0.0087 15.5 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Nse5 PF08691.10 CCC71583.1 - 1.5e-121 406.6 23.2 1.9e-121 406.3 23.2 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Ribosomal_S17e PF00833.18 CCC71584.1 - 7.6e-57 190.5 0.5 8.9e-57 190.3 0.5 1.1 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_L4 PF00573.22 CCC71585.1 - 7.7e-49 166.0 0.0 1e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S13 PF00416.22 CCC71586.1 - 1.7e-57 193.3 3.2 1.9e-57 193.1 3.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 CCC71586.1 - 0.0017 17.2 0.0 0.0019 17.1 0.0 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.6 CCC71586.1 - 0.097 12.9 0.3 0.51 10.6 0.1 2.2 1 1 0 2 2 2 0 Helix-hairpin-helix motif H2TH PF06831.14 CCC71586.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain Homeodomain PF00046.29 CCC71587.1 - 1.8e-17 62.9 4.1 4.5e-17 61.6 4.1 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 CCC71587.1 - 0.0033 17.3 0.2 0.011 15.6 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain YdaS_antitoxin PF15943.5 CCC71587.1 - 0.042 13.7 0.1 0.091 12.6 0.1 1.5 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DotA PF11388.8 CCC71587.1 - 1.8 8.8 7.3 0.75 10.0 0.1 3.2 3 1 0 3 3 3 0 Phagosome trafficking protein DotA Sad1_UNC PF07738.13 CCC71588.1 - 3.6e-29 101.5 0.2 8.3e-29 100.3 0.2 1.7 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal AhpC-TSA PF00578.21 CCC71589.1 - 1.5e-33 115.4 0.0 4.7e-33 113.7 0.0 1.7 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 CCC71589.1 - 8.4e-16 58.0 0.1 1.7e-15 57.0 0.0 1.5 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.9 CCC71589.1 - 1.1e-07 31.5 0.2 2.3e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 CCC71589.1 - 0.049 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 SCO1/SenC ubiquitin PF00240.23 CCC71590.1 - 0.00066 19.4 0.0 0.0021 17.8 0.0 1.9 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 CCC71590.1 - 0.014 15.2 3.7 2.3 8.1 0.0 3.8 4 0 0 4 4 4 0 Ubiquitin-2 like Rad60 SUMO-like HIG_1_N PF04588.13 CCC71591.1 - 3.3e-16 59.2 2.5 4.6e-16 58.8 2.5 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region M PF02370.16 CCC71591.1 - 0.036 14.6 0.6 0.036 14.6 0.6 3.7 3 1 0 3 3 3 0 M protein repeat HemX PF04375.14 CCC71591.1 - 0.037 13.3 5.6 0.047 13.0 5.6 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Vps5 PF09325.10 CCC71591.1 - 0.047 13.2 9.5 0.061 12.9 9.6 1.2 1 0 0 1 1 1 0 Vps5 C terminal like Atg14 PF10186.9 CCC71591.1 - 0.083 12.0 8.9 0.097 11.7 8.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 CCC71591.1 - 0.15 10.7 3.5 0.17 10.5 3.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cauli_AT PF03233.13 CCC71591.1 - 0.48 10.3 4.2 0.75 9.7 4.2 1.2 1 0 0 1 1 1 0 Aphid transmission protein DUF5446 PF17522.2 CCC71591.1 - 2.7 8.2 7.2 2.2 8.5 5.0 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5446) Ndc1_Nup PF09531.10 CCC71592.1 - 2.8e-88 297.2 16.5 9.9e-88 295.4 16.5 1.8 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Rad52_Rad22 PF04098.15 CCC71593.1 - 2.4e-54 183.4 0.0 3.8e-54 182.8 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein MSC PF09402.10 CCC71594.1 - 3.3e-107 358.9 2.8 3.3e-107 358.9 2.8 3.5 4 1 0 5 5 5 1 Man1-Src1p-C-terminal domain HeH PF12949.7 CCC71594.1 - 1e-12 47.5 0.3 2.8e-12 46.1 0.3 1.7 1 0 0 1 1 1 1 HeH/LEM domain MHC_I PF00129.18 CCC71594.1 - 0.015 14.9 0.1 0.043 13.4 0.1 1.7 1 0 0 1 1 1 0 Class I Histocompatibility antigen, domains alpha 1 and 2 THF_DHG_CYH PF00763.23 CCC71594.1 - 0.074 13.3 4.9 0.46 10.8 0.2 3.2 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AI-2E_transport PF01594.16 CCC71594.1 - 0.079 12.1 1.1 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 AI-2E family transporter Occludin_ELL PF07303.13 CCC71594.1 - 3.3 8.5 10.1 0.16 12.7 0.3 3.8 3 0 0 3 3 3 0 Occludin homology domain A_deaminase PF00962.22 CCC71595.1 - 3.8e-132 440.6 0.0 5.4e-132 440.1 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase CGI-121 PF08617.10 CCC71596.1 - 1.6e-44 151.9 0.1 1.8e-44 151.7 0.1 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 TPT PF03151.16 CCC71598.1 - 2.2e-15 56.8 20.3 8.6e-08 31.9 0.5 3.0 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 CCC71598.1 - 1.1e-07 32.1 26.6 0.00031 20.9 4.4 3.8 4 0 0 4 4 4 3 EamA-like transporter family PUNUT PF16913.5 CCC71598.1 - 5.1e-07 29.2 2.6 5.1e-07 29.2 2.6 1.9 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport UAA PF08449.11 CCC71598.1 - 5.3e-07 29.1 2.5 5.3e-07 29.1 2.5 2.5 2 1 1 3 3 3 1 UAA transporter family EmrE PF13536.6 CCC71598.1 - 0.00019 21.1 7.1 0.0044 16.7 0.3 2.4 2 0 0 2 2 2 2 Putative multidrug resistance efflux transporter FAM176 PF14851.6 CCC71598.1 - 0.047 13.4 0.1 1.9 8.1 0.0 2.9 3 0 0 3 3 3 0 FAM176 family TMEM223 PF14640.6 CCC71598.1 - 0.1 12.7 0.5 0.31 11.2 0.1 2.0 2 1 0 2 2 2 0 Transmembrane protein 223 TMEM234 PF10639.9 CCC71598.1 - 0.28 11.2 12.3 1.4 9.0 1.0 3.0 3 0 0 3 3 3 0 Putative transmembrane family 234 zf-C2H2_4 PF13894.6 CCC71599.1 - 4.2e-06 27.1 16.5 0.032 15.1 1.2 4.7 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.26 CCC71599.1 - 0.00052 20.3 17.3 0.0028 18.0 2.7 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2HE PF16278.5 CCC71599.1 - 0.0018 18.7 1.7 0.065 13.7 0.1 3.0 2 0 0 2 2 2 1 C2HE / C2H2 / C2HC zinc-binding finger zf-H2C2_2 PF13465.6 CCC71599.1 - 0.0052 17.2 1.2 0.0052 17.2 1.2 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_3rep PF18868.1 CCC71599.1 - 0.08 13.6 5.0 0.69 10.6 0.0 3.4 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats NifU PF01106.17 CCC71599.1 - 0.19 11.9 0.2 2.5 8.3 0.0 2.3 2 0 0 2 2 2 0 NifU-like domain zf-C2H2_6 PF13912.6 CCC71599.1 - 0.25 11.4 4.3 4.1 7.5 0.1 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger HNH PF01844.23 CCC71599.1 - 1.1 9.5 7.1 6.5 7.0 0.5 3.0 2 1 0 2 2 2 0 HNH endonuclease Glyco_hydro_76 PF03663.14 CCC71600.1 - 4.9e-159 529.7 29.8 5.7e-159 529.5 29.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF2347 PF09804.9 CCC71601.1 - 3.2e-58 197.6 2.0 8.5e-30 104.3 0.3 2.2 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.9 CCC71601.1 - 1.5e-12 46.9 0.6 8e-12 44.5 0.5 1.9 1 1 0 1 1 1 1 Transport protein Avl9 DUF4484 PF14831.6 CCC71601.1 - 1.4e-10 41.6 0.1 7.1e-08 32.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4484) SPA PF08616.10 CCC71601.1 - 1.8e-05 24.6 0.3 3.5e-05 23.7 0.3 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 CCC71601.1 - 0.0099 16.4 0.2 0.019 15.5 0.2 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking F_bP_aldolase PF01116.20 CCC71602.1 - 1.5e-89 300.2 0.1 1.7e-89 300.0 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II DWNN PF08783.11 CCC71603.1 - 1.5e-30 105.3 1.0 1.2e-29 102.4 0.0 2.3 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.6 CCC71603.1 - 2.3e-08 33.7 5.3 2.3e-08 33.7 5.3 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-Nse PF11789.8 CCC71603.1 - 8.6e-06 25.5 2.4 1e-05 25.3 0.7 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 CCC71603.1 - 0.00063 19.9 0.0 0.0017 18.5 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-CCHC PF00098.23 CCC71603.1 - 0.0013 18.7 2.2 0.0013 18.7 2.2 2.0 3 0 0 3 3 3 1 Zinc knuckle zf-CCHC_5 PF14787.6 CCC71603.1 - 0.014 15.1 1.8 0.071 12.8 0.2 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 CCC71603.1 - 0.054 13.5 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 Zinc knuckle PYNP_C PF07831.13 CCC71603.1 - 0.066 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain TF_Zn_Ribbon PF08271.12 CCC71603.1 - 0.25 10.9 0.1 0.25 10.9 0.1 2.4 3 0 0 3 3 3 0 TFIIB zinc-binding Rubredoxin PF00301.20 CCC71603.1 - 0.74 9.9 7.7 6.3 6.9 0.0 3.4 4 0 0 4 4 4 0 Rubredoxin TFIIA_gamma_C PF02751.14 CCC71604.1 - 3.2e-23 81.6 1.5 5.2e-23 80.9 1.5 1.4 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 CCC71604.1 - 1.3e-22 79.5 0.2 1.7e-22 79.1 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TCTP PF00838.17 CCC71605.1 - 1.6e-72 243.2 0.7 1.8e-72 243.1 0.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein adh_short PF00106.25 CCC71606.1 - 1.3e-31 109.6 0.2 7.8e-22 77.7 0.3 3.0 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 CCC71606.1 - 9.2e-16 58.1 0.8 8.7e-13 48.4 0.1 3.0 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCC71606.1 - 0.00071 19.5 0.0 0.18 11.7 0.0 2.9 3 0 0 3 3 3 1 KR domain Epimerase PF01370.21 CCC71606.1 - 0.0087 15.5 0.0 0.3 10.5 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PGAP1 PF07819.13 CCC71607.1 - 1.3e-06 28.3 0.0 8.1e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.14 CCC71607.1 - 3.1e-06 26.8 0.0 8e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 CCC71607.1 - 1.6e-05 24.9 0.0 7.3e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 CCC71607.1 - 7.5e-05 22.2 0.2 0.00064 19.1 0.0 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.20 CCC71607.1 - 0.00011 22.0 0.0 0.0011 18.6 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.15 CCC71607.1 - 0.0022 17.2 0.0 0.0067 15.6 0.0 1.8 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase DUF3095 PF11294.8 CCC71607.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) Abhydrolase_6 PF12697.7 CCC71607.1 - 0.17 12.4 0.0 0.32 11.6 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family BLI1 PF17324.2 CCC71608.1 - 6.5e-50 168.4 8.7 7.3e-50 168.3 8.7 1.0 1 0 0 1 1 1 1 BLOC-1 interactor 1 BLOC1_2 PF10046.9 CCC71608.1 - 0.00089 19.5 6.3 0.0018 18.5 5.9 1.8 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TBK1_ULD PF18396.1 CCC71608.1 - 0.055 13.4 0.9 2.2 8.3 0.3 2.2 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Lyase_8_N PF08124.11 CCC71608.1 - 0.084 11.8 2.5 0.099 11.5 2.5 1.0 1 0 0 1 1 1 0 Polysaccharide lyase family 8, N terminal alpha-helical domain UPF0449 PF15136.6 CCC71608.1 - 0.095 13.2 7.1 2.8 8.5 0.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 NdhM PF10664.9 CCC71608.1 - 0.12 12.7 1.3 0.25 11.6 0.8 1.8 1 1 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M JIP_LZII PF16471.5 CCC71608.1 - 0.14 12.3 5.3 0.45 10.7 2.0 2.3 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II RICH PF05062.12 CCC71608.1 - 0.31 11.4 7.4 0.06 13.7 3.0 2.0 2 1 0 2 2 2 0 RICH domain ApoC-I PF04691.12 CCC71608.1 - 0.38 10.7 7.2 0.5 10.3 0.5 3.2 2 2 1 3 3 3 0 Apolipoprotein C-I (ApoC-1) CUE PF02845.16 CCC71609.1 - 1.8e-05 24.3 0.0 3.7e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 CUE domain SID-1_RNA_chan PF13965.6 CCC71609.1 - 4.5 5.5 10.0 8.6 4.6 10.0 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 UPF0203 PF05254.12 CCC71610.1 - 6.1e-26 90.5 2.6 8e-26 90.1 2.6 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.16 CCC71610.1 - 0.0062 16.7 0.4 0.01 16.0 0.4 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Pet191_N PF10203.9 CCC71610.1 - 0.16 12.3 1.9 15 6.0 0.1 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 DASH_Ask1 PF08655.10 CCC71611.1 - 6.2e-28 96.5 0.7 1.2e-27 95.6 0.7 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 Frag1 PF10277.9 CCC71612.1 - 4e-81 271.7 24.2 4.7e-81 271.5 24.2 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family GEN1_C PF18380.1 CCC71613.1 - 0.019 15.9 2.7 0.053 14.4 2.7 1.7 1 0 0 1 1 1 0 Holliday junction resolvase Gen1 C-terminal domain DUF1682 PF07946.14 CCC71613.1 - 0.66 9.1 9.7 0.83 8.8 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) V_ATPase_I PF01496.19 CCC71613.1 - 1 7.2 6.9 1.2 6.9 6.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MscS_TM PF12794.7 CCC71613.1 - 6.4 5.5 4.6 8.9 5.1 4.6 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Eisosome1 PF12757.7 CCC71614.1 - 4e-22 78.8 6.9 4e-22 78.8 6.9 3.3 3 1 1 4 4 4 1 Eisosome protein 1 Foamy_BEL PF03274.14 CCC71614.1 - 0.033 13.5 0.0 0.072 12.4 0.0 1.5 1 0 0 1 1 1 0 Foamy virus BEL 1/2 protein Histone PF00125.24 CCC71615.1 - 1.6e-35 122.3 9.5 6.8e-35 120.3 9.8 1.8 1 1 1 2 2 2 1 Core histone H2A/H2B/H3/H4 Spt5_N PF11942.8 CCC71615.1 - 0.032 15.2 11.6 0.15 13.0 5.1 2.4 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CENP-S PF15630.6 CCC71615.1 - 0.068 13.6 0.6 0.21 12.0 0.2 1.9 2 0 0 2 2 2 0 CENP-S protein Actin PF00022.19 CCC71616.1 - 4.9e-23 81.4 0.6 5e-21 74.8 0.1 2.9 2 1 0 2 2 2 1 Actin FtsA PF14450.6 CCC71616.1 - 0.00013 22.4 0.1 0.00024 21.5 0.1 1.5 1 0 0 1 1 1 1 Cell division protein FtsA PilM_2 PF11104.8 CCC71616.1 - 0.0029 16.7 0.0 0.19 10.7 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; MreB_Mbl PF06723.13 CCC71616.1 - 0.022 13.6 0.1 13 4.5 0.0 3.0 3 0 0 3 3 3 0 MreB/Mbl protein UPF0158 PF03682.13 CCC71616.1 - 0.03 14.3 0.1 0.59 10.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0158) Pkinase PF00069.25 CCC71617.1 - 4.6e-39 134.4 0.1 5.2e-33 114.5 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71617.1 - 3.7e-18 65.7 0.1 4e-14 52.5 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 CCC71617.1 - 3.5e-05 23.3 0.0 0.00012 21.5 0.0 1.9 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 CCC71617.1 - 0.00078 19.4 0.0 0.13 12.2 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family Abhydrolase_2 PF02230.16 CCC71617.1 - 0.15 11.9 1.1 0.34 10.7 0.6 1.8 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase zf-C2H2 PF00096.26 CCC71618.1 - 6.9e-09 35.7 11.8 0.00027 21.2 2.6 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC71618.1 - 4.1e-08 33.3 17.3 7.5e-07 29.3 2.8 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC71618.1 - 7.4e-07 29.5 12.0 0.0021 18.7 2.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.15 CCC71618.1 - 0.0001 22.2 4.7 0.016 15.2 0.5 3.0 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_jaz PF12171.8 CCC71618.1 - 0.012 15.9 16.4 0.024 14.9 4.3 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 CCC71618.1 - 0.061 13.1 1.9 1.2 9.0 0.2 2.6 1 1 1 2 2 2 0 GAGA factor zf-C2HE PF16278.5 CCC71618.1 - 0.1 13.1 9.8 0.52 10.8 0.9 3.3 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf_C2H2_ZHX PF18387.1 CCC71618.1 - 0.22 11.2 5.2 1.3 8.7 0.3 2.7 1 1 1 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-Di19 PF05605.12 CCC71618.1 - 0.23 11.8 3.9 0.42 10.9 3.9 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.7 CCC71618.1 - 0.69 10.3 7.5 1.2 9.5 2.0 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 CCC71618.1 - 2.7 8.5 6.9 1.7 9.2 2.0 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.6 CCC71618.1 - 4.7 7.3 13.6 4.3 7.5 4.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Serglycin PF04360.12 CCC71619.1 - 0.039 13.9 2.8 0.055 13.4 1.8 1.8 1 1 1 2 2 2 0 Serglycin Borrelia_P83 PF05262.11 CCC71619.1 - 3.2 6.1 18.1 3.5 6.0 18.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Neur_chan_memb PF02932.16 CCC71619.1 - 7.9 6.5 5.4 11 6.0 5.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CorA PF01544.18 CCC71620.1 - 4.2e-37 128.1 6.4 3e-21 76.0 0.2 3.6 4 0 0 4 4 4 3 CorA-like Mg2+ transporter protein Bap31 PF05529.12 CCC71621.1 - 7.9e-23 80.8 3.0 1.3e-22 80.1 3.0 1.3 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region Lip_prot_lig_C PF10437.9 CCC71621.1 - 0.00062 19.7 0.1 0.001 19.0 0.1 1.3 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus Bap31_Bap29_C PF18035.1 CCC71621.1 - 0.0012 18.8 4.6 0.0018 18.3 4.6 1.3 1 0 0 1 1 1 1 Bap31/Bap29 cytoplasmic coiled-coil domain Sec2p PF06428.11 CCC71621.1 - 0.03 14.3 0.8 0.048 13.6 0.8 1.3 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p BMFP PF04380.13 CCC71621.1 - 0.058 13.9 0.2 0.083 13.4 0.2 1.3 1 0 0 1 1 1 0 Membrane fusogenic activity LapA_dom PF06305.11 CCC71621.1 - 0.22 11.3 4.5 4.6 7.1 0.0 3.1 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain Hyccin PF09790.9 CCC71622.1 - 0.068 12.3 0.0 0.068 12.3 0.0 1.1 1 0 0 1 1 1 0 Hyccin NDK PF00334.19 CCC71623.1 - 4.2e-54 182.2 0.0 4.8e-54 182.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SRF-TF PF00319.18 CCC71624.1 - 3.8e-21 74.3 0.2 6e-21 73.7 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Nucleoporin_FG PF13634.6 CCC71625.1 - 9e-36 122.6 348.2 9.2e-07 29.6 28.9 12.1 2 1 9 11 11 11 9 Nucleoporin FG repeat region Nucleoporin2 PF04096.14 CCC71625.1 - 5.3e-35 120.7 0.0 1.1e-34 119.6 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase zf-CCCH PF00642.24 CCC71626.1 - 9e-18 63.7 15.9 1.2e-08 34.7 2.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 CCC71626.1 - 1.8e-05 24.6 18.9 0.014 15.5 9.0 2.4 2 0 0 2 2 2 2 Zinc finger domain Nepo_coat_N PF03689.15 CCC71626.1 - 0.037 14.0 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain zf-CCCH_4 PF18044.1 CCC71626.1 - 0.055 13.3 15.4 1.2 9.0 7.8 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 CCC71626.1 - 4.3 8.1 14.7 0.4 11.4 1.9 2.8 1 1 1 2 2 2 0 Torus domain V-ATPase_C PF03223.15 CCC71627.1 - 1.1e-118 396.9 1.3 1.2e-118 396.7 1.3 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NUC130_3NT PF08158.12 CCC71627.1 - 0.0012 19.2 0.2 1.5 9.2 0.0 2.6 2 0 0 2 2 2 2 NUC130/3NT domain Kinesin PF00225.23 CCC71628.1 - 2.3e-43 148.4 2.6 2.3e-43 148.4 2.6 2.6 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 CCC71628.1 - 1e-12 48.2 0.5 1e-12 48.2 0.5 2.8 3 0 0 3 3 3 1 Microtubule binding Cep57_CLD_2 PF14197.6 CCC71628.1 - 0.022 14.8 3.3 0.022 14.8 3.3 3.9 1 1 3 4 4 4 0 Centrosome localisation domain of PPC89 CreA PF05981.12 CCC71628.1 - 0.061 13.3 1.3 0.41 10.6 0.2 2.4 2 0 0 2 2 2 0 CreA protein Cnn_1N PF07989.11 CCC71628.1 - 0.094 12.9 22.2 1 9.5 3.3 3.9 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 DUF600 PF04634.12 CCC71628.1 - 3 7.9 7.9 0.14 12.2 0.5 2.5 3 0 0 3 3 3 0 Protein of unknown function, DUF600 HA2 PF04408.23 CCC71629.1 - 2e-19 69.9 0.0 4.3e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 CCC71629.1 - 2.1e-13 50.4 0.0 6.8e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 CCC71629.1 - 5.6e-11 42.8 0.0 1.4e-10 41.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 CCC71629.1 - 2.4e-08 33.9 0.1 4.2e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 CCC71629.1 - 1.8e-05 25.0 0.1 6.3e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCC71629.1 - 8.3e-05 23.0 0.0 0.00016 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCC71629.1 - 0.0021 17.8 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.22 CCC71629.1 - 0.0075 15.9 0.0 0.041 13.5 0.0 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 CCC71629.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 CCC71629.1 - 0.024 14.4 0.9 0.042 13.6 0.0 1.9 2 0 0 2 2 1 0 P-loop containing region of AAA domain Septin PF00735.18 CCC71629.1 - 0.025 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_23 PF13476.6 CCC71629.1 - 0.025 15.1 0.1 0.059 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 CCC71629.1 - 0.072 13.0 0.0 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 CCC71629.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.9 CCC71629.1 - 0.11 11.8 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.27 CCC71629.1 - 0.56 10.7 2.0 1.2 9.6 0.4 2.3 2 1 0 2 2 1 0 ABC transporter Sen15 PF09631.10 CCC71630.1 - 7.5e-27 93.6 0.1 8.6e-27 93.4 0.1 1.0 1 0 0 1 1 1 1 Sen15 protein Mpp10 PF04006.12 CCC71630.1 - 0.2 10.1 0.1 0.23 9.9 0.1 1.0 1 0 0 1 1 1 0 Mpp10 protein DUF4448 PF14610.6 CCC71631.1 - 1.3e-56 191.4 0.3 2.1e-56 190.7 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) RRM_1 PF00076.22 CCC71633.1 - 0.11 12.3 0.1 1 9.3 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.20 CCC71634.1 - 7.3e-46 156.5 1.1 7.3e-46 156.5 1.1 3.1 3 0 0 3 3 3 2 Hsp70 protein Atypical_Card PF18461.1 CCC71634.1 - 0.03 14.5 0.1 0.099 12.9 0.1 1.9 1 0 0 1 1 1 0 Atypical caspase recruitment domain TetR_C_4 PF08359.11 CCC71634.1 - 0.046 13.9 0.1 0.15 12.2 0.1 1.9 1 0 0 1 1 1 0 YsiA-like protein, C-terminal region Utp14 PF04615.13 CCC71634.1 - 0.099 11.2 25.6 0.17 10.5 25.6 1.2 1 0 0 1 1 1 0 Utp14 protein DUF3135 PF11333.8 CCC71634.1 - 0.66 10.3 2.7 30 5.0 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3135) FSA_C PF10479.9 CCC71634.1 - 2.5 6.1 15.2 3.8 5.5 15.2 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Rep_2 PF01719.17 CCC71635.1 - 0.039 13.7 2.1 0.092 12.5 2.1 1.6 1 0 0 1 1 1 0 Plasmid replication protein DASH_Dad4 PF08650.10 CCC71635.1 - 0.3 11.1 5.8 0.34 10.9 1.4 3.2 3 1 0 3 3 3 0 DASH complex subunit Dad4 Tropomyosin_1 PF12718.7 CCC71635.1 - 5.2 7.2 7.9 6.3 6.9 3.2 2.5 2 0 0 2 2 2 0 Tropomyosin like GAF_2 PF13185.6 CCC71636.1 - 2.8e-07 30.9 0.0 3.5e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 CCC71636.1 - 0.0064 17.1 0.0 0.0075 16.9 0.0 1.2 1 0 0 1 1 1 1 GAF domain AlaDh_PNT_C PF01262.21 CCC71636.1 - 0.058 12.7 0.0 0.078 12.3 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain BOP1NT PF08145.12 CCC71637.1 - 1e-101 340.3 7.1 1.6e-101 339.6 7.1 1.4 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 CCC71637.1 - 7.4e-23 80.4 7.0 3.4e-09 37.2 0.3 6.8 6 1 1 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC71637.1 - 5.9e-08 32.9 0.8 0.0018 18.5 0.0 5.2 4 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain NAPRTase PF04095.16 CCC71637.1 - 0.046 13.3 0.1 0.079 12.6 0.1 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Colicin-DNase PF12639.7 CCC71637.1 - 0.61 10.9 2.5 0.78 10.6 0.3 2.3 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin EF1G PF00647.19 CCC71639.1 - 1.2e-47 160.4 0.1 2.7e-47 159.2 0.1 1.6 2 0 0 2 2 2 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 CCC71639.1 - 8.6e-12 45.1 0.1 8.6e-12 45.1 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 CCC71639.1 - 5.6e-11 42.6 0.0 1.8e-10 41.0 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 CCC71639.1 - 0.00017 21.9 0.0 0.00037 20.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCC71639.1 - 0.0023 17.9 0.1 0.0049 16.9 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCC71639.1 - 0.0085 16.3 0.0 0.026 14.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 CCC71639.1 - 0.017 15.4 0.0 0.062 13.6 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 CCC71639.1 - 0.049 13.9 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein OAD_gamma PF04277.13 CCC71639.1 - 4.1 8.1 6.0 2.2 9.0 3.5 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Ank_2 PF12796.7 CCC71640.1 - 7.2e-17 61.8 0.6 1.3e-09 38.5 0.1 3.2 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 CCC71640.1 - 7e-16 58.4 7.2 3.6e-07 30.6 0.4 3.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCC71640.1 - 1.8e-10 40.1 7.5 0.0069 16.8 0.1 5.2 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 CCC71640.1 - 1.2e-09 38.1 9.4 3.1e-05 24.2 0.1 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 CCC71640.1 - 4.8e-08 33.1 1.0 0.00083 19.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DUF5439 PF17507.2 CCC71640.1 - 0.019 15.2 0.0 0.042 14.1 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5439) zf-CHY PF05495.12 CCC71641.1 - 4.1e-10 40.0 14.8 8e-10 39.1 14.8 1.6 1 1 0 1 1 1 1 CHY zinc finger zinc_ribbon_12 PF11331.8 CCC71641.1 - 0.0042 16.8 1.8 0.011 15.5 0.3 2.2 2 0 0 2 2 2 1 Probable zinc-ribbon domain HypA PF01155.19 CCC71641.1 - 0.8 9.8 5.4 0.36 10.8 2.8 1.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF4674 PF15719.5 CCC71641.1 - 1.3 9.0 6.1 0.97 9.4 2.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4674) Ldh_1_C PF02866.18 CCC71642.1 - 7.6e-52 175.6 0.3 1.3e-51 174.8 0.3 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 CCC71642.1 - 4.6e-45 153.2 0.0 6.7e-45 152.6 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 CCC71642.1 - 4.2e-05 22.7 0.0 5.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 CCC71642.1 - 0.0018 18.7 0.1 0.054 13.9 0.0 2.8 2 1 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 CCC71642.1 - 0.066 13.1 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H-binding ParBc PF02195.18 CCC71643.1 - 2.4e-11 43.8 0.0 3.1e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Cyto_heme_lyase PF01265.17 CCC71644.1 - 3.6e-31 108.9 18.1 5.3e-29 101.7 18.1 2.6 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Flavoprotein PF02441.19 CCC71645.1 - 2e-51 173.9 0.2 2e-51 173.9 0.2 1.9 2 0 0 2 2 2 1 Flavoprotein Sgf11_N PF18519.1 CCC71645.1 - 0.066 12.8 4.1 0.32 10.6 0.0 2.6 2 0 0 2 2 2 0 SAGA-associated factor 11 N-terminal domain NOA36 PF06524.12 CCC71645.1 - 1.2 8.4 17.8 2.5 7.4 17.8 1.5 1 0 0 1 1 1 0 NOA36 protein FTR_C PF02741.15 CCC71645.1 - 2.1 8.3 4.0 0.83 9.7 0.2 2.0 2 0 0 2 2 2 0 FTR, proximal lobe TFB6 PF17110.5 CCC71645.1 - 9.2 6.0 11.0 23 4.7 11.0 1.7 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Peptidase_S24 PF00717.23 CCC71646.1 - 4.2e-09 36.2 0.0 6.4e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase S24-like Ydc2-catalyt PF09159.10 CCC71647.1 - 2e-50 172.1 0.7 3.4e-50 171.3 0.7 1.4 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 DUF4261 PF14080.6 CCC71647.1 - 0.0022 18.1 0.0 0.0057 16.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4261) Pox_A22 PF04848.13 CCC71647.1 - 0.012 15.8 0.2 0.54 10.4 0.0 3.0 2 1 0 2 2 2 0 Poxvirus A22 protein DUF1244 PF06844.11 CCC71647.1 - 0.042 14.0 0.0 0.25 11.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) DEAD PF00270.29 CCC71649.1 - 0.014 15.2 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase MIP PF00230.20 CCC71650.1 - 1.3e-36 126.5 14.7 1.4e-36 126.3 14.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein HOK_GEF PF01848.16 CCC71650.1 - 1.1 8.8 4.7 1.6 8.2 0.1 2.4 2 0 0 2 2 2 0 Hok/gef family ARPC4 PF05856.12 CCC71651.1 - 8.6e-73 243.4 4.1 9.6e-73 243.3 4.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Fungal_trans PF04082.18 CCC71652.1 - 3.1e-18 65.8 1.9 8.5e-18 64.3 1.9 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC71652.1 - 1.6e-10 40.9 7.8 3.3e-10 39.9 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipoprotein_3 PF00938.17 CCC71652.1 - 0.046 13.9 0.1 0.16 12.1 0.1 2.0 1 0 0 1 1 1 0 Lipoprotein Mt_ATP-synt_D PF05873.12 CCC71653.1 - 1.3e-17 64.0 7.1 1.7e-17 63.7 7.1 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF677 PF05055.12 CCC71653.1 - 0.0007 18.6 4.8 0.0013 17.7 4.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF677) Pet20 PF08692.10 CCC71653.1 - 0.079 13.7 1.4 0.089 13.5 0.7 1.4 1 1 1 2 2 2 0 Mitochondrial protein Pet20 ApoLp-III PF07464.11 CCC71653.1 - 0.21 11.7 5.4 0.12 12.4 2.6 1.9 1 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) GIDA_assoc PF13932.6 CCC71653.1 - 0.57 10.3 5.2 0.73 10.0 5.2 1.1 1 0 0 1 1 1 0 GidA associated domain DUF1104 PF06518.11 CCC71653.1 - 0.87 10.0 5.6 0.34 11.3 2.0 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF1104) DUF5339 PF17274.2 CCC71653.1 - 2.3 9.1 4.7 1.8 9.5 0.1 2.6 3 1 0 3 3 3 0 Family of unknown function (DUF5339) AAA_12 PF13087.6 CCC71654.1 - 1.7e-59 200.8 0.0 4.2e-59 199.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 CCC71654.1 - 4.2e-53 180.8 2.2 7.1e-53 180.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 CCC71654.1 - 7.1e-12 45.4 0.0 5.2e-10 39.4 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCC71654.1 - 1.5e-11 44.8 0.0 6.7e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 CCC71654.1 - 3.4e-07 30.2 0.3 0.25 11.1 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 CCC71654.1 - 1.6e-05 24.6 0.2 8.6e-05 22.2 0.0 2.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain ResIII PF04851.15 CCC71654.1 - 4.2e-05 23.6 0.0 0.00017 21.6 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 CCC71654.1 - 4.7e-05 23.7 0.1 0.0013 19.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 CCC71654.1 - 6.5e-05 22.9 0.0 0.00075 19.4 0.0 2.6 2 0 0 2 2 2 1 Helicase PhoH PF02562.16 CCC71654.1 - 0.00081 18.9 0.0 0.0065 15.9 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 CCC71654.1 - 0.0014 18.5 0.2 0.0078 16.0 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase PIF1 PF05970.14 CCC71654.1 - 0.002 17.4 0.0 0.1 11.7 0.0 2.5 2 0 0 2 2 2 1 PIF1-like helicase AAA_24 PF13479.6 CCC71654.1 - 0.0022 17.8 0.0 0.011 15.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 CCC71654.1 - 0.0045 16.8 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.9 CCC71654.1 - 0.0082 15.4 0.1 0.028 13.7 0.1 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 CCC71654.1 - 0.0082 16.6 0.0 0.034 14.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 CCC71654.1 - 0.0093 16.4 0.0 0.02 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 CCC71654.1 - 0.014 14.3 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF853 PF05872.12 CCC71654.1 - 0.014 14.0 0.0 0.025 13.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) T2SSE PF00437.20 CCC71654.1 - 0.042 12.9 0.0 0.086 11.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.23 CCC71654.1 - 0.064 13.3 0.1 0.24 11.4 0.0 2.1 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 CCC71654.1 - 0.064 13.1 0.2 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_14 PF13173.6 CCC71654.1 - 0.073 13.1 0.0 0.9 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CCC71654.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 CCC71655.1 - 4.1e-13 49.6 0.4 0.0018 19.1 0.0 5.6 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC71655.1 - 0.00011 22.4 0.0 1.8 8.9 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 CCC71655.1 - 0.0029 16.9 0.0 0.023 13.9 0.0 2.3 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller DUF1748 PF08520.10 CCC71656.1 - 3.7e-18 65.2 0.2 4.6e-18 64.9 0.2 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PPTA PF01239.22 CCC71657.1 - 1.2e-40 136.1 14.3 4.1e-08 32.7 0.2 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DnaJ PF00226.31 CCC71658.1 - 5.4e-17 61.7 1.3 5.4e-17 61.7 1.3 2.2 2 0 0 2 2 2 1 DnaJ domain ORC5_C PF14630.6 CCC71659.1 - 3.9e-64 216.9 0.5 5.7e-64 216.4 0.5 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 CCC71659.1 - 9.6e-06 26.1 0.2 2.6e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 CCC71659.1 - 1e-05 25.8 0.0 2.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain zf-CCHC PF00098.23 CCC71660.1 - 0.00017 21.5 3.1 0.00027 20.9 3.1 1.3 1 0 0 1 1 1 1 Zinc knuckle ABC_tran_CTD PF16326.5 CCC71660.1 - 0.016 15.5 1.1 0.044 14.0 0.0 2.4 3 0 0 3 3 3 0 ABC transporter C-terminal domain DUF4868 PF16162.5 CCC71660.1 - 0.019 14.9 0.0 0.038 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4868) DUF4600 PF15372.6 CCC71660.1 - 0.043 14.2 1.7 0.11 12.9 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) zf-CCHC_4 PF14392.6 CCC71660.1 - 0.28 11.0 0.6 0.48 10.2 0.6 1.4 1 0 0 1 1 1 0 Zinc knuckle DUF1664 PF07889.12 CCC71660.1 - 0.32 11.0 6.1 0.26 11.4 0.6 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) CENP-H PF05837.12 CCC71660.1 - 2.1 8.8 6.1 1.7 9.1 0.6 2.7 3 0 0 3 3 3 0 Centromere protein H (CENP-H) RT_RNaseH_2 PF17919.1 CCC71661.1 - 2.2e-30 104.6 0.0 5.9e-30 103.3 0.0 1.8 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 CCC71661.1 - 5.7e-30 103.7 0.0 1.1e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 CCC71661.1 - 5.1e-29 101.4 0.5 1.1e-28 100.3 0.5 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Integrase_H2C2 PF17921.1 CCC71661.1 - 9.5e-16 57.7 0.1 2e-15 56.6 0.1 1.6 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 CCC71661.1 - 1.1e-14 54.6 0.0 2.9e-14 53.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Peptidase_A2B PF12384.8 CCC71661.1 - 0.00013 21.6 0.1 0.00039 20.0 0.1 1.8 1 0 0 1 1 1 1 Ty3 transposon peptidase gag-asp_proteas PF13975.6 CCC71661.1 - 0.00033 21.2 0.0 0.0012 19.3 0.0 2.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 CCC71661.1 - 0.0016 19.1 0.0 0.0063 17.1 0.0 2.1 2 0 0 2 2 2 1 Aspartyl protease WD40 PF00400.32 CCC71663.1 - 9.3e-22 76.9 6.8 3.1e-06 27.8 0.3 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC71663.1 - 8.6e-07 29.2 2.5 0.91 9.9 0.0 5.0 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 CCC71663.1 - 0.013 14.2 0.3 0.092 11.4 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 MRP-S32 PF10210.9 CCC71663.1 - 0.014 15.9 0.1 0.028 15.0 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 TPR_1 PF00515.28 CCC71664.1 - 9e-35 117.1 22.0 5.7e-06 25.9 0.1 9.9 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 CCC71664.1 - 9.4e-34 112.8 22.7 8.1e-05 22.4 0.1 10.4 11 0 0 11 11 10 7 Tetratricopeptide repeat ANAPC3 PF12895.7 CCC71664.1 - 1.9e-25 88.8 18.2 5.5e-24 84.2 0.2 4.8 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.6 CCC71664.1 - 3.4e-21 73.6 28.9 4.2e-05 23.4 0.1 11.1 13 0 0 13 13 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 CCC71664.1 - 1.7e-20 73.1 13.5 1.8e-09 37.7 0.0 8.9 7 2 2 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 CCC71664.1 - 5.1e-17 61.1 0.8 0.0015 19.1 0.0 9.4 8 2 2 10 10 10 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCC71664.1 - 6.9e-17 61.7 3.6 0.002 18.6 0.2 7.6 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 CCC71664.1 - 1.1e-14 54.8 2.2 2e-05 25.1 0.0 5.9 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 CCC71664.1 - 2e-13 49.3 12.2 2.4e-05 24.1 0.1 8.2 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCC71664.1 - 1.1e-09 38.0 11.8 0.26 11.8 0.0 8.4 10 0 0 10 10 8 2 Tetratricopeptide repeat TPR_6 PF13174.6 CCC71664.1 - 2.9e-08 33.8 14.2 0.58 10.9 0.1 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCC71664.1 - 3e-08 33.2 11.8 2.7e-05 23.7 0.1 7.1 6 2 2 8 8 8 1 TPR repeat TPR_10 PF13374.6 CCC71664.1 - 3.4e-08 33.1 9.8 0.028 14.3 0.0 6.8 9 0 0 9 9 8 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 CCC71664.1 - 2.6e-05 24.2 9.6 1.6 8.9 0.0 4.9 4 0 0 4 4 4 3 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 CCC71664.1 - 2.6e-05 23.6 0.2 0.27 10.4 0.1 3.5 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 CCC71664.1 - 0.00077 19.6 0.0 0.038 14.1 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 CCC71664.1 - 0.0019 17.6 0.3 0.46 9.8 0.0 3.9 4 1 1 5 5 5 2 MalT-like TPR region DUF2989 PF11207.8 CCC71664.1 - 0.0043 16.9 3.1 0.14 11.9 0.1 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2989) SRP_TPR_like PF17004.5 CCC71664.1 - 0.0061 16.6 5.1 3.5 7.7 0.0 4.1 3 1 1 4 4 4 1 Putative TPR-like repeat TPR_21 PF09976.9 CCC71664.1 - 0.014 15.1 0.1 5.8 6.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain TPR_4 PF07721.14 CCC71664.1 - 0.073 13.7 0.2 1.8e+02 3.2 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat RPN7 PF10602.9 CCC71664.1 - 0.12 12.0 1.8 2 8.1 0.3 3.2 2 1 0 2 2 2 0 26S proteasome subunit RPN7 ADK PF00406.22 CCC71666.1 - 6.9e-48 162.6 0.0 9.8e-48 162.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 CCC71666.1 - 3.3e-37 128.0 0.0 5.5e-37 127.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 CCC71666.1 - 4.3e-08 33.8 0.0 7.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 CCC71666.1 - 8.6e-06 26.0 0.0 6.7e-05 23.1 0.0 2.4 3 1 0 3 3 3 1 AAA domain Thymidylate_kin PF02223.17 CCC71666.1 - 3.7e-05 23.5 0.2 0.15 11.7 0.0 2.2 1 1 1 2 2 2 2 Thymidylate kinase SRP54 PF00448.22 CCC71666.1 - 0.024 14.3 0.0 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Ploopntkinase3 PF18751.1 CCC71666.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 adh_short PF00106.25 CCC71667.1 - 1.7e-47 161.4 0.2 2.1e-47 161.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 CCC71667.1 - 5.5e-29 101.4 0.1 6.8e-29 101.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 CCC71667.1 - 1.1e-10 41.8 0.0 1.5e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 CCC71667.1 - 0.00055 19.5 0.1 0.00089 18.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pan3_PK PF18101.1 CCC71668.1 - 1.1e-50 171.2 0.1 2e-50 170.4 0.1 1.4 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 CCC71668.1 - 0.0016 17.8 0.0 0.0046 16.4 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain HIGH_NTase1 PF05636.11 CCC71668.1 - 0.1 11.8 0.2 0.16 11.2 0.2 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase G6PD_C PF02781.16 CCC71669.1 - 5.8e-93 311.2 0.0 7.3e-93 310.9 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 CCC71669.1 - 3.2e-51 174.4 0.0 5.8e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Sugar_tr PF00083.24 CCC71670.1 - 5.1e-158 526.6 24.2 5.9e-158 526.4 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC71670.1 - 5.4e-27 94.6 36.5 5.6e-21 74.9 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 CCC71670.1 - 0.0004 19.8 2.4 0.0004 19.8 2.4 2.2 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Thia_YuaJ PF09515.10 CCC71670.1 - 0.028 14.4 6.9 0.034 14.2 1.2 2.6 2 0 0 2 2 2 0 Thiamine transporter protein (Thia_YuaJ) DUF1772 PF08592.11 CCC71670.1 - 0.22 11.8 2.7 0.85 9.9 0.1 3.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1772) DUF2530 PF10745.9 CCC71670.1 - 3.4 8.0 6.3 4.1 7.7 1.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) GSHPx PF00255.19 CCC71671.1 - 1.4e-47 159.8 1.2 1.8e-47 159.4 1.2 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 CCC71671.1 - 0.0019 18.1 0.4 0.0067 16.4 0.4 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 CCC71671.1 - 0.053 13.2 0.1 0.65 9.7 0.0 2.0 2 0 0 2 2 2 0 Redoxin DUF5126 PF17166.4 CCC71671.1 - 0.083 12.8 0.0 8.1 6.4 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5126) DUF4174 PF13778.6 CCC71671.1 - 0.084 13.3 0.0 0.18 12.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) PLA2_B PF01735.18 CCC71672.1 - 3.1e-212 705.3 2.8 5.1e-212 704.6 2.8 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain IBR PF01485.21 CCC71672.1 - 0.026 14.7 1.5 0.049 13.9 1.5 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain SOR_SNZ PF01680.17 CCC71673.1 - 1.5e-107 358.1 1.9 1.9e-107 357.7 1.9 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 CCC71673.1 - 1.8e-09 37.3 1.1 1.3e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.17 CCC71673.1 - 0.0024 17.2 0.1 0.092 12.1 0.0 2.6 2 1 1 3 3 3 1 Thiamine monophosphate synthase TetR_C_27 PF17935.1 CCC71673.1 - 0.0056 16.7 0.0 0.02 15.0 0.0 1.8 2 0 0 2 2 2 1 Tetracyclin repressor-like, C-terminal domain NMO PF03060.15 CCC71673.1 - 0.0069 15.8 0.7 0.66 9.3 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase Dus PF01207.17 CCC71673.1 - 0.008 15.3 0.2 4.9 6.2 0.1 2.9 2 1 1 3 3 3 2 Dihydrouridine synthase (Dus) NanE PF04131.14 CCC71673.1 - 0.023 13.9 0.7 0.25 10.5 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 CCC71673.1 - 0.027 13.7 0.1 0.86 8.7 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 CCC71673.1 - 0.063 12.7 0.1 0.58 9.6 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein SNO PF01174.19 CCC71674.1 - 6.9e-77 257.5 0.0 7.9e-77 257.4 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 CCC71674.1 - 6.4e-09 35.7 0.0 2.4e-08 33.8 0.0 1.8 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_S51 PF03575.17 CCC71674.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 1 0 1 1 1 0 Peptidase family S51 DEAD PF00270.29 CCC71676.1 - 4.5e-09 36.3 0.0 7.9e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase TniB PF05621.11 CCC71676.1 - 0.028 13.8 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PTPLA PF04387.14 CCC71676.1 - 0.058 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase-like protein, PTPLA ResIII PF04851.15 CCC71676.1 - 0.086 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_C PF00271.31 CCC71677.1 - 1.8e-06 28.3 0.0 2.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MFS_1_like PF12832.7 CCC71678.1 - 0.046 12.6 0.3 0.17 10.7 0.1 1.7 2 0 0 2 2 2 0 MFS_1 like family TRI12 PF06609.13 CCC71679.1 - 2.5e-06 26.2 16.3 5.3e-06 25.1 16.2 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.16 CCC71679.1 - 9.1e-05 21.5 35.2 0.0021 17.0 35.2 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 CCC71679.1 - 0.00012 21.1 11.0 0.00012 21.1 11.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Hph PF13694.6 CCC71680.1 - 2.3e-12 47.6 9.7 2.3e-12 47.6 9.7 3.0 2 1 1 3 3 3 1 Sec63/Sec62 complex-interacting family Fib_alpha PF08702.10 CCC71680.1 - 0.024 14.8 5.9 0.078 13.2 5.8 2.0 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 CCC71680.1 - 0.18 11.7 10.5 0.053 13.5 6.6 2.1 2 0 0 2 2 2 0 Prefoldin subunit Myosin_head PF00063.21 CCC71681.1 - 2.2e-281 935.0 11.2 2.2e-281 935.0 11.2 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.19 CCC71681.1 - 4.3e-26 91.2 0.5 4.3e-26 91.2 0.5 3.1 4 0 0 4 4 4 1 DIL domain IQ PF00612.27 CCC71681.1 - 1.8e-07 30.3 17.3 0.39 10.6 0.2 5.7 5 0 0 5 5 5 4 IQ calmodulin-binding motif Myosin_N PF02736.19 CCC71681.1 - 0.0032 17.3 0.2 0.011 15.6 0.2 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 CCC71681.1 - 0.0065 16.7 0.4 0.039 14.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 CCC71681.1 - 0.12 12.7 0.0 0.54 10.6 0.0 2.1 1 0 0 1 1 1 0 AAA ATPase domain TolA_bind_tri PF16331.5 CCC71681.1 - 0.18 11.9 15.2 0.14 12.3 7.9 3.3 2 0 0 2 2 2 0 TolA binding protein trimerisation ABC_tran PF00005.27 CCC71681.1 - 0.68 10.4 0.0 0.68 10.4 0.0 3.0 2 1 0 2 2 2 0 ABC transporter Synaptobrevin PF00957.21 CCC71682.1 - 2.1e-31 107.5 1.3 2.4e-31 107.3 1.3 1.0 1 0 0 1 1 1 1 Synaptobrevin UPF0258 PF06789.12 CCC71682.1 - 0.2 11.8 1.3 0.27 11.3 1.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF3168 PF11367.8 CCC71683.1 - 0.018 15.2 0.0 0.049 13.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3168) bVLRF1 PF18826.1 CCC71683.1 - 0.067 13.1 0.1 0.19 11.6 0.1 1.7 1 0 0 1 1 1 0 bacteroidetes VLRF1 release factor CENP-H PF05837.12 CCC71683.1 - 2.1 8.8 5.2 0.73 10.3 1.7 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) bZIP_2 PF07716.15 CCC71684.1 - 7.9e-12 45.1 11.0 1.5e-11 44.2 11.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.21 CCC71684.1 - 1.2e-07 31.7 13.4 2.3e-07 30.8 13.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 CCC71684.1 - 0.0053 17.2 4.0 0.01 16.3 4.0 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor Glyco_transf_25 PF01755.17 CCC71684.1 - 0.03 14.2 0.1 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) DivIC PF04977.15 CCC71684.1 - 0.63 9.8 3.6 0.99 9.2 3.0 1.6 1 1 0 1 1 1 0 Septum formation initiator YabA PF06156.13 CCC71684.1 - 1.1 10.0 5.1 2.2 9.0 3.0 2.1 2 0 0 2 2 2 0 Initiation control protein YabA Urm1 PF09138.11 CCC71685.1 - 4.7e-35 119.8 0.5 5.7e-35 119.6 0.5 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) REGB_T4 PF10715.9 CCC71686.1 - 0.062 13.5 1.2 0.1 12.8 1.2 1.4 1 1 0 1 1 1 0 T4-page Endoribonuclease RegB DUF262 PF03235.14 CCC71686.1 - 4.7 7.3 15.2 11 6.1 15.2 1.7 1 1 0 1 1 1 0 Protein of unknown function DUF262 COPIIcoated_ERV PF07970.12 CCC71687.1 - 1.6e-72 244.0 0.0 2e-72 243.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCC71687.1 - 1.3e-28 99.1 0.3 2.7e-28 98.1 0.3 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PX PF00787.24 CCC71688.1 - 1.2e-21 76.8 1.3 3.7e-21 75.2 0.7 1.8 1 1 1 2 2 2 1 PX domain Histone PF00125.24 CCC71689.1 - 1.5e-24 86.8 0.0 2e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 CCC71689.1 - 2.5e-19 69.3 1.0 4.5e-19 68.5 1.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 CCC71689.1 - 0.0054 16.8 0.1 0.012 15.6 0.1 1.7 2 0 0 2 2 2 1 hTAFII28-like protein conserved region SAM_2 PF07647.17 CCC71690.1 - 8.7e-08 32.2 2.1 7e-07 29.3 0.1 2.6 2 1 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CCC71690.1 - 2.7e-05 24.5 0.1 6.7e-05 23.3 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.10 CCC71690.1 - 0.025 14.7 0.0 0.068 13.3 0.0 1.7 1 0 0 1 1 1 0 IGR protein motif SUIM_assoc PF16619.5 CCC71690.1 - 2.6 8.2 10.8 0.5 10.5 4.4 3.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PDEase_I PF00233.19 CCC71691.1 - 2.7e-49 168.0 2.9 4.8e-49 167.2 2.9 1.4 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 CCC71691.1 - 0.0087 16.3 0.0 0.022 15.0 0.0 1.7 1 0 0 1 1 1 1 HD domain eIF2A PF08662.11 CCC71692.1 - 1.3e-26 93.7 2.4 6.1e-24 85.0 0.7 3.5 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 CCC71692.1 - 5.7e-09 35.7 0.0 1.5e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ldi PF18566.1 CCC71692.1 - 0.048 13.2 0.8 0.084 12.4 0.8 1.3 1 0 0 1 1 1 0 Linalool dehydratase/isomerase Ribosomal_L29 PF00831.23 CCC71692.1 - 0.05 13.6 0.1 0.13 12.3 0.1 1.7 1 0 0 1 1 1 0 Ribosomal L29 protein Proteasome PF00227.26 CCC71693.1 - 7.5e-49 165.8 0.0 9.6e-49 165.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 CCC71693.1 - 6.2e-12 45.0 0.0 6.2e-12 45.0 0.0 2.4 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature DLH PF01738.18 CCC71694.1 - 1.5e-40 139.1 0.0 1.7e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 CCC71694.1 - 0.034 13.4 0.0 2.5 7.3 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 CCC71694.1 - 0.078 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 CCC71694.1 - 0.09 12.7 0.1 0.66 9.9 0.1 1.9 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Zn_clus PF00172.18 CCC71695.1 - 1.8e-10 40.7 9.5 3.1e-10 40.0 9.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ZapB PF06005.12 CCC71695.1 - 1.2 9.6 3.7 5.3 7.6 0.1 3.2 3 0 0 3 3 3 0 Cell division protein ZapB DUP PF00674.18 CCC71696.1 - 3.2e-14 52.9 3.5 3.2e-14 52.9 3.5 1.8 1 1 1 2 2 2 1 DUP family DUF962 PF06127.11 CCC71696.1 - 0.057 13.5 2.2 0.089 12.9 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF962) DUF4131 PF13567.6 CCC71696.1 - 0.088 12.5 0.3 0.13 11.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) CH PF00307.31 CCC71697.1 - 4.5e-16 59.0 0.0 6.8e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 CCC71697.1 - 0.066 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 CDC24 Calponin Peroxin-22 PF12827.7 CCC71698.1 - 5.9e-31 106.7 0.4 8e-31 106.3 0.4 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family SpoIIIAH PF12685.7 CCC71698.1 - 0.00037 20.4 0.4 0.00041 20.2 0.4 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein NCE101 PF11654.8 CCC71698.1 - 0.0027 17.4 0.1 0.0051 16.5 0.1 1.4 1 0 0 1 1 1 1 Non-classical export protein 1 Rad1 PF02144.16 CCC71699.1 - 2.5e-69 233.4 2.2 2.5e-69 233.4 2.2 1.4 2 0 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 PBP_sp32 PF07222.12 CCC71699.1 - 0.0049 16.4 3.7 0.018 14.5 3.7 1.7 1 1 0 1 1 1 1 Proacrosin binding protein sp32 Ribosomal_L7Ae PF01248.26 CCC71700.1 - 6.2e-23 80.4 0.2 8.1e-23 80.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.12 CCC71700.1 - 0.053 13.8 0.3 0.2 12.0 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) GDI PF00996.18 CCC71701.1 - 9.3e-44 149.6 0.1 2e-43 148.5 0.1 1.4 1 1 0 1 1 1 1 GDP dissociation inhibitor ETF PF01012.21 CCC71701.1 - 0.1 12.5 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein domain Kelch_6 PF13964.6 CCC71702.1 - 6.9e-07 29.3 4.7 1.3 9.5 0.1 5.8 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 CCC71702.1 - 1.8e-06 28.1 0.3 0.2 12.0 0.0 4.3 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_4 PF13418.6 CCC71702.1 - 5.1e-06 26.4 6.1 0.0035 17.3 0.1 4.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_5 PF13854.6 CCC71702.1 - 3.1e-05 23.8 7.6 2.9 8.0 0.0 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 CCC71702.1 - 0.00099 18.6 1.6 2.6 7.7 0.0 3.8 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 CCC71702.1 - 0.031 14.3 4.9 2.9 8.0 0.3 4.8 6 0 0 6 6 6 0 Kelch motif LRR_8 PF13855.6 CCC71704.1 - 1.4e-11 44.0 44.7 2e-05 24.3 0.3 6.8 5 2 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 CCC71704.1 - 1.7e-11 44.1 55.8 6.7e-06 26.4 3.0 8.0 3 2 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 CCC71704.1 - 0.0001 22.0 29.0 0.88 9.8 0.8 8.6 8 0 0 8 8 8 5 Leucine Rich repeat LRR_9 PF14580.6 CCC71704.1 - 0.031 13.8 18.5 0.45 10.0 0.3 4.7 3 2 1 5 5 5 0 Leucine-rich repeat Aldedh PF00171.22 CCC71705.1 - 3.4e-182 606.1 0.5 4.2e-182 605.8 0.5 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 CCC71705.1 - 0.0011 18.5 0.1 0.6 9.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) RSF PF14876.6 CCC71706.1 - 1.5e-05 24.2 0.5 1.5e-05 24.2 0.5 2.1 3 0 0 3 3 3 1 Respiratory growth transcriptional regulator SRI PF08236.11 CCC71706.1 - 0.033 14.4 0.3 0.12 12.6 0.1 2.0 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Aldedh PF00171.22 CCC71707.1 - 4.1e-15 55.3 0.1 1.6e-10 40.1 0.0 2.3 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Ribosomal_L28e PF01778.17 CCC71708.1 - 3.4e-41 140.6 0.6 3.4e-41 140.6 0.6 2.1 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.14 CCC71708.1 - 4e-31 107.6 17.9 4e-31 107.6 17.9 2.7 2 1 1 3 3 3 1 Mak16 protein C-terminal region BUD22 PF09073.10 CCC71708.1 - 0.00012 21.6 25.5 0.00017 21.1 25.5 1.2 1 0 0 1 1 1 1 BUD22 PYC_OADA PF02436.18 CCC71708.1 - 0.24 11.1 6.1 0.53 10.0 6.0 1.7 1 1 0 1 1 1 0 Conserved carboxylase domain Hid1 PF12722.7 CCC71708.1 - 9.3 4.2 10.1 12 3.8 10.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LDB19 PF13002.7 CCC71709.1 - 3.3e-89 297.7 0.8 5.3e-89 297.1 0.8 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.29 CCC71709.1 - 0.00068 19.7 0.2 0.0025 17.9 0.1 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain PMT PF02366.18 CCC71710.1 - 9.2e-89 297.2 18.8 9.2e-89 297.2 18.8 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCC71710.1 - 1.8e-58 197.4 13.4 1.8e-58 197.4 13.4 2.2 2 1 0 2 2 2 1 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCC71710.1 - 6.8e-23 81.5 0.3 6.8e-23 81.5 0.3 1.6 2 0 0 2 2 2 1 MIR domain Med15_fungi PF05397.12 CCC71711.1 - 1.6e-24 86.3 1.7 1.6e-24 86.3 1.7 3.4 3 1 0 3 3 3 1 Mediator complex subunit 15 KIX_2 PF16987.5 CCC71711.1 - 3.7e-14 52.5 0.8 3.7e-14 52.5 0.8 2.5 2 0 0 2 2 2 1 KIX domain Gal11_ABD1 PF18535.1 CCC71711.1 - 0.0063 16.6 1.0 0.04 14.0 1.0 2.4 1 0 0 1 1 1 1 Gal11 activator-binding domain (ABD1) DUF5644 PF18712.1 CCC71711.1 - 0.023 14.7 3.0 0.11 12.5 3.0 2.2 1 0 0 1 1 1 0 Family of unknown function (DUF5644) DUF966 PF06136.13 CCC71711.1 - 0.089 12.5 8.8 0.23 11.1 8.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF966) GSH_synth_ATP PF03917.17 CCC71712.1 - 3.4e-116 388.1 0.0 4e-116 387.9 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 CCC71712.1 - 2.6e-29 101.7 0.0 6e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic glutathione synthase EI24 PF07264.11 CCC71713.1 - 0.0091 16.3 0.2 0.012 15.9 0.2 1.1 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) EI24 PF07264.11 CCC71714.1 - 2.5e-10 40.9 4.9 2.5e-10 40.9 4.9 2.1 1 1 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) Pkinase PF00069.25 CCC71715.1 - 3.9e-62 210.0 1.9 8.1e-62 209.0 0.1 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71715.1 - 6.4e-23 81.4 0.0 1.1e-22 80.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC71715.1 - 2.8e-09 36.7 0.0 5.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 CCC71715.1 - 0.0023 16.7 0.0 0.0046 15.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 CCC71715.1 - 0.0042 16.2 1.4 0.028 13.5 0.1 2.6 3 0 0 3 3 3 1 Seadornavirus VP7 RIO1 PF01163.22 CCC71715.1 - 0.02 14.5 0.2 0.048 13.2 0.2 1.5 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 CCC71715.1 - 0.024 14.0 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 CCC71715.1 - 0.029 14.3 0.0 0.052 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAS PF00989.25 CCC71715.1 - 0.077 13.0 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 PAS fold FTA2 PF13095.6 CCC71715.1 - 0.11 12.2 0.7 0.39 10.3 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Mannosyl_trans3 PF11051.8 CCC71716.1 - 1e-69 235.0 1.4 1.3e-69 234.6 1.4 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Exo_endo_phos PF03372.23 CCC71718.1 - 3e-10 40.0 0.0 1.6e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_60s PF00428.19 CCC71721.1 - 1.7e-23 83.0 16.4 2e-23 82.8 16.4 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein MAGE_N PF12440.8 CCC71721.1 - 0.31 11.7 7.8 0.4 11.4 7.8 1.2 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal SIL1 PF16782.5 CCC71722.1 - 3.2e-106 354.8 15.5 4.3e-106 354.4 15.5 1.1 1 0 0 1 1 1 1 Nucleotide exchange factor SIL1 DUF775 PF05603.12 CCC71723.1 - 1.2e-63 214.3 0.2 1.3e-63 214.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) DUF1598 PF07643.11 CCC71723.1 - 0.04 14.2 0.0 0.077 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1598) tRNA-synt_1c PF00749.21 CCC71724.1 - 3.9e-108 361.1 0.0 5.4e-108 360.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain TUG-UBL1 PF11470.8 CCC71724.1 - 0.015 15.5 0.1 0.049 13.9 0.1 1.8 2 0 0 2 2 2 0 TUG ubiquitin-like domain bHLH-MYC_N PF14215.6 CCC71724.1 - 0.16 12.2 0.0 0.71 10.1 0.0 1.9 2 0 0 2 2 2 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal SMC_N PF02463.19 CCC71725.1 - 3e-21 75.9 15.0 8.7e-21 74.4 15.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCC71725.1 - 1.7e-09 38.5 43.5 1.7e-09 38.5 43.5 5.3 2 2 1 3 3 1 1 AAA domain AAA_29 PF13555.6 CCC71725.1 - 4.2e-05 23.2 0.0 9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 CCC71725.1 - 0.0017 18.1 33.1 0.0017 18.1 33.1 4.4 1 1 0 2 2 1 1 AAA ATPase domain AAA_21 PF13304.6 CCC71725.1 - 0.0042 16.9 0.2 0.0042 16.9 0.2 4.0 2 2 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 CCC71725.1 - 0.0084 15.7 0.0 0.029 13.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 CCC71725.1 - 0.041 13.5 3.8 0.15 11.6 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 CCC71725.1 - 0.059 13.5 0.5 1.1 9.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CCC71725.1 - 0.079 12.9 0.8 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.27 CCC71725.1 - 0.19 12.2 0.0 0.19 12.2 0.0 5.5 4 2 0 4 4 3 0 ABC transporter COOH-NH2_lig PF14395.6 CCC71725.1 - 0.44 9.7 6.9 0.14 11.4 0.6 2.9 3 0 0 3 3 3 0 Phage phiEco32-like COOH.NH2 ligase-type 2 FUSC PF04632.12 CCC71725.1 - 0.53 8.7 5.2 0.096 11.2 0.1 2.1 3 0 0 3 3 3 0 Fusaric acid resistance protein family Baculo_PEP_C PF04513.12 CCC71725.1 - 0.56 10.3 30.1 0.19 11.8 0.8 5.8 4 3 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phe_tRNA-synt_N PF02912.18 CCC71725.1 - 0.6 10.1 11.7 0.024 14.6 1.7 3.8 3 0 0 3 3 3 0 Aminoacyl tRNA synthetase class II, N-terminal domain Trimer_CC PF08954.11 CCC71725.1 - 1.8 8.2 9.1 0.14 11.8 0.4 3.3 3 0 0 3 3 3 0 Trimerisation motif INTS5_N PF14837.6 CCC71725.1 - 2.4 7.7 6.8 0.3 10.6 0.2 2.8 3 0 0 3 3 3 0 Integrator complex subunit 5 N-terminus B56 PF01603.20 CCC71727.1 - 5e-169 562.7 19.0 1.5e-159 531.4 14.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) EMP24_GP25L PF01105.24 CCC71728.1 - 1.6e-30 106.4 0.0 1.8e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD GTP_EFTU_D4 PF14578.6 CCC71728.1 - 0.02 14.8 0.0 0.55 10.2 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu domain 4 DUF2569 PF10754.9 CCC71728.1 - 0.062 13.7 0.6 0.098 13.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) Pet127 PF08634.10 CCC71729.1 - 8e-102 340.3 8.9 4.6e-101 337.9 6.0 2.7 2 1 0 2 2 2 1 Mitochondrial protein Pet127 RPN1_RPN2_N PF17781.1 CCC71729.1 - 0.0029 17.1 0.1 0.0065 15.9 0.1 1.6 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain Glyco_hydro_72 PF03198.14 CCC71730.1 - 3.9e-148 492.8 5.5 5.1e-148 492.5 5.5 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.18 CCC71730.1 - 0.0018 17.8 0.1 0.011 15.2 0.1 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Macoilin PF09726.9 CCC71730.1 - 0.058 12.0 10.6 0.073 11.6 10.6 1.1 1 0 0 1 1 1 0 Macoilin family RNA_pol_Rpc4 PF05132.14 CCC71730.1 - 0.52 10.7 2.5 0.85 10.0 2.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 BUD22 PF09073.10 CCC71730.1 - 1.5 8.0 10.3 2.2 7.5 10.3 1.2 1 0 0 1 1 1 0 BUD22 Sporozoite_P67 PF05642.11 CCC71730.1 - 2 6.4 16.8 2.6 6.0 16.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Apt1 PF10351.9 CCC71730.1 - 2 7.2 15.5 2.9 6.6 15.5 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain ANAPC1 PF12859.7 CCC71730.1 - 2.9 8.4 8.3 8.7 6.9 8.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 1 bZIP_1 PF00170.21 CCC71731.1 - 8.3e-05 22.6 12.6 8.4e-05 22.6 10.8 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 CCC71731.1 - 0.0061 16.6 9.9 0.0061 16.6 9.9 2.2 2 0 0 2 2 2 1 Basic region leucine zipper DUF3439 PF11921.8 CCC71731.1 - 0.46 10.5 13.2 1.3 9.1 13.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) bZIP_Maf PF03131.17 CCC71731.1 - 5.2 7.6 18.7 0.41 11.2 7.4 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor LETM1 PF07766.13 CCC71732.1 - 4.3e-98 327.9 4.9 6.1e-98 327.4 4.9 1.2 1 0 0 1 1 1 1 LETM1-like protein Acyl-CoA_ox_N PF14749.6 CCC71732.1 - 0.069 13.7 0.4 0.35 11.4 0.0 2.4 2 1 1 3 3 3 0 Acyl-coenzyme A oxidase N-terminal TOM13 PF08219.11 CCC71733.1 - 4.3e-25 87.5 0.1 5.6e-25 87.1 0.1 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 SRP1_TIP1 PF00660.17 CCC71734.1 - 2e-34 117.6 0.5 2e-34 117.6 0.5 1.9 2 0 0 2 2 2 1 Seripauperin and TIP1 family DUF1387 PF07139.11 CCC71734.1 - 1.9 8.1 6.8 2.6 7.7 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Macoilin PF09726.9 CCC71734.1 - 6.4 5.2 9.7 7.8 4.9 9.7 1.1 1 0 0 1 1 1 0 Macoilin family ABC2_membrane PF01061.24 CCC71735.1 - 6.9e-68 228.2 58.4 9.5e-35 119.9 15.8 3.1 4 0 0 4 4 4 2 ABC-2 type transporter ABC_tran PF00005.27 CCC71735.1 - 2.1e-29 102.8 0.1 2.1e-16 60.7 0.1 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 CCC71735.1 - 8.1e-28 96.2 5.0 7.6e-25 86.6 0.1 3.7 4 0 0 4 4 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.7 CCC71735.1 - 2.3e-10 40.2 47.0 1.8e-05 24.0 17.3 3.4 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 CCC71735.1 - 2.1e-05 24.5 1.6 0.0045 16.8 0.2 2.7 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 CCC71735.1 - 0.00015 21.7 0.4 0.00015 21.7 0.4 1.9 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 CCC71735.1 - 0.00019 21.9 0.1 0.0004 20.8 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 CCC71735.1 - 0.00047 19.6 0.0 0.0048 16.4 0.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCC71735.1 - 0.0049 17.4 1.8 0.012 16.1 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 CCC71735.1 - 0.018 15.3 0.1 0.043 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 CCC71735.1 - 0.037 13.6 0.1 0.09 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 CCC71735.1 - 0.039 13.9 0.1 0.12 12.3 0.1 1.8 1 0 0 1 1 1 0 NACHT domain AAA_29 PF13555.6 CCC71735.1 - 0.074 12.8 0.4 0.2 11.4 0.4 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.6 CCC71735.1 - 0.22 11.2 0.2 0.39 10.4 0.2 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 CCC71735.1 - 0.29 10.7 2.0 1.7 8.2 2.0 2.2 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SRP1_TIP1 PF00660.17 CCC71737.1 - 1.7e-24 85.8 0.8 3.2e-24 84.9 0.0 1.8 2 1 0 2 2 2 1 Seripauperin and TIP1 family PIR PF00399.19 CCC71737.1 - 1.1e-06 28.0 7.1 1.1e-05 24.8 7.1 2.9 1 0 0 1 1 1 1 Yeast PIR protein repeat LamB PF02264.15 CCC71737.1 - 0.046 13.6 1.3 0.056 13.3 1.3 1.2 1 0 0 1 1 1 0 LamB porin Mito_fiss_reg PF05308.11 CCC71737.1 - 1.4 9.0 7.0 1.8 8.6 7.0 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Macoilin PF09726.9 CCC71737.1 - 3.7 6.0 8.4 4 5.9 8.4 1.1 1 0 0 1 1 1 0 Macoilin family RNA_polI_A14 PF08203.11 CCC71737.1 - 8.4 7.2 8.8 8.5 7.2 7.3 1.8 2 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Pannexin_like PF12534.8 CCC71737.1 - 8.6 5.3 5.7 11 5.0 5.7 1.1 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 EF-hand_4 PF12763.7 CCC71738.1 - 5.1e-29 100.3 0.0 8.1e-15 54.7 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 CCC71738.1 - 5.6e-08 33.1 0.0 0.0058 17.1 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 CCC71738.1 - 9.6e-07 27.9 0.0 0.021 14.4 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 CCC71738.1 - 1.8e-06 27.4 0.1 1.2 9.2 0.0 4.8 4 0 0 4 4 4 1 EF-hand domain DUF1720 PF08226.11 CCC71738.1 - 0.002 18.5 34.3 0.005 17.2 16.4 10.6 4 2 5 9 9 9 4 Domain of unknown function (DUF1720) DSBA PF01323.20 CCC71738.1 - 0.0021 17.9 0.0 1.1 9.0 0.0 2.8 2 0 0 2 2 2 2 DSBA-like thioredoxin domain IL15 PF02372.15 CCC71738.1 - 0.13 12.3 0.2 0.41 10.7 0.2 1.9 1 0 0 1 1 1 0 Interleukin 15 E3_binding PF02817.17 CCC71738.1 - 0.15 12.4 0.0 0.4 11.1 0.0 1.7 1 0 0 1 1 1 0 e3 binding domain LCIB_C_CA PF18599.1 CCC71738.1 - 2.2 7.5 6.2 0.17 11.2 0.4 2.1 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases RraA-like PF03737.15 CCC71739.1 - 1.1e-29 103.6 0.1 1.3e-29 103.3 0.1 1.1 1 0 0 1 1 1 1 Aldolase/RraA NTF2 PF02136.20 CCC71740.1 - 1.2e-35 122.7 0.3 1.3e-35 122.6 0.3 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.6 CCC71740.1 - 0.00041 19.6 0.3 0.0026 17.0 0.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) DUF4440 PF14534.6 CCC71740.1 - 0.088 13.2 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) Sec3_C PF09763.9 CCC71741.1 - 5.8e-159 530.7 32.1 5.8e-159 530.7 32.1 2.5 3 0 0 3 3 3 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.6 CCC71741.1 - 6.6e-29 99.9 0.6 2.2e-28 98.2 0.6 2.0 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Pre-PUA PF17832.1 CCC71742.1 - 3.4e-26 91.8 0.8 7.3e-26 90.7 0.7 1.6 2 0 0 2 2 2 1 Pre-PUA-like domain PUA PF01472.20 CCC71742.1 - 7.4e-22 77.1 0.1 1.1e-21 76.6 0.1 1.2 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 CCC71742.1 - 0.00018 21.7 1.5 0.00022 21.4 0.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1947) GN3L_Grn1 PF08701.11 CCC71743.1 - 2.9e-23 81.7 8.5 2.9e-23 81.7 8.5 2.3 2 0 0 2 2 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 CCC71743.1 - 1.8e-18 66.6 0.1 3.5e-14 52.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 CCC71743.1 - 6.7e-09 35.5 0.1 1.5e-07 31.1 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 CCC71743.1 - 2.1e-06 27.9 0.8 0.24 11.4 0.1 3.7 3 1 0 4 4 4 2 Dynamin family RsgA_GTPase PF03193.16 CCC71743.1 - 9.9e-05 22.3 0.4 0.0039 17.1 0.4 2.4 1 1 0 1 1 1 1 RsgA GTPase AIG1 PF04548.16 CCC71743.1 - 0.00019 20.8 0.0 0.0011 18.3 0.0 2.0 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.27 CCC71743.1 - 0.0015 18.1 0.1 0.24 10.9 0.0 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MeaB PF03308.16 CCC71743.1 - 0.031 13.3 0.0 0.06 12.3 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 CCC71743.1 - 0.038 13.6 0.1 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 CCC71743.1 - 0.065 13.8 0.0 0.22 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 CCC71743.1 - 0.074 13.4 1.5 6.3 7.1 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain Roc PF08477.13 CCC71743.1 - 0.12 12.6 0.1 7.2 6.9 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Torsin PF06309.11 CCC71743.1 - 0.17 12.0 0.1 0.33 11.1 0.1 1.4 1 0 0 1 1 1 0 Torsin Peptidase_M3 PF01432.20 CCC71743.1 - 0.52 9.5 2.2 0.83 8.8 2.2 1.2 1 0 0 1 1 1 0 Peptidase family M3 GDA1_CD39 PF01150.17 CCC71744.1 - 5.1e-141 470.2 0.1 6.7e-141 469.8 0.1 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DDOST_48kD PF03345.14 CCC71746.1 - 5.9e-121 404.2 6.5 7.4e-121 403.9 6.5 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2555 PF10742.9 CCC71746.1 - 0.083 12.7 0.5 6.5 6.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2555) Chordopox_G3 PF06129.12 CCC71746.1 - 0.088 13.5 0.1 13 6.6 0.0 2.8 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Orai-1 PF07856.12 CCC71746.1 - 0.15 11.7 0.1 0.15 11.7 0.1 1.5 2 0 0 2 2 2 0 Mediator of CRAC channel activity Prefoldin_2 PF01920.20 CCC71747.1 - 6.9e-22 77.4 3.3 7.8e-22 77.2 3.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF2383 PF09537.10 CCC71747.1 - 0.008 16.5 0.3 0.021 15.2 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2383) vATP-synt_E PF01991.18 CCC71747.1 - 0.011 15.2 1.7 0.14 11.5 0.2 2.1 2 0 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Occludin_ELL PF07303.13 CCC71747.1 - 0.04 14.7 0.9 4.1 8.2 0.1 2.1 2 0 0 2 2 2 0 Occludin homology domain Prefoldin PF02996.17 CCC71747.1 - 0.085 12.8 3.4 1.8 8.5 3.4 2.1 1 1 0 1 1 1 0 Prefoldin subunit DUF5424 PF17462.2 CCC71748.1 - 0.003 17.5 0.7 0.0045 17.0 0.7 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5424) BORCS7 PF16088.5 CCC71748.1 - 0.011 16.0 2.9 0.011 16.0 2.9 2.3 2 1 0 2 2 2 0 BLOC-1-related complex sub-unit 7 DUF3450 PF11932.8 CCC71748.1 - 0.037 13.3 1.5 0.12 11.7 1.5 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) KxDL PF10241.9 CCC71748.1 - 0.19 12.1 4.5 0.28 11.5 1.1 2.8 1 1 1 2 2 2 0 Uncharacterized conserved protein PCYCGC PF13798.6 CCC71748.1 - 0.19 11.5 0.8 0.7 9.7 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif DRIM PF07539.12 CCC71749.1 - 2.6e-172 574.4 7.6 2.6e-172 574.4 7.6 5.2 4 2 0 4 4 4 2 Down-regulated in metastasis Xpo1 PF08389.12 CCC71749.1 - 0.0032 17.6 11.0 0.016 15.3 3.4 5.7 6 0 0 6 6 6 1 Exportin 1-like protein HEAT_2 PF13646.6 CCC71749.1 - 0.011 16.1 0.3 27 5.2 0.0 4.8 5 0 0 5 5 5 0 HEAT repeats DUF5106 PF17127.4 CCC71749.1 - 0.08 13.2 0.4 0.7 10.2 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5106) Rad21_Rec8_N PF04825.13 CCC71750.1 - 2.7e-24 85.4 0.5 2.7e-24 85.4 0.5 2.3 3 0 0 3 3 3 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 CCC71750.1 - 1.9e-10 39.9 0.0 4.1e-10 38.8 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ATP-synt_DE_N PF02823.16 CCC71751.1 - 2.8e-16 59.2 0.0 3.9e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUP PF00674.18 CCC71752.1 - 1.1e-16 60.8 0.1 2.2e-16 59.9 0.1 1.5 1 1 0 1 1 1 1 DUP family AA_permease PF00324.21 CCC71753.1 - 1.7e-131 439.1 31.1 1.9e-131 439.0 31.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC71753.1 - 5.3e-25 88.1 34.3 6.9e-25 87.8 34.3 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1712 PF08217.11 CCC71754.1 - 8.2e-159 529.9 4.7 9.9e-159 529.7 4.7 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) SRP54 PF00448.22 CCC71755.1 - 5.8e-78 261.0 3.7 8e-78 260.6 0.5 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 CCC71755.1 - 8.5e-30 103.3 7.8 8.5e-30 103.3 7.8 4.1 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 CCC71755.1 - 1.4e-15 57.3 0.7 1.4e-15 57.3 0.7 1.9 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain cobW PF02492.19 CCC71755.1 - 7e-05 22.5 2.2 0.00034 20.3 0.9 2.6 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 CCC71755.1 - 0.00023 21.3 0.1 0.0011 19.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 CCC71755.1 - 0.00024 21.5 0.1 0.0012 19.2 0.1 2.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 CCC71755.1 - 0.00033 20.7 0.0 0.00094 19.2 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRPRB PF09439.10 CCC71755.1 - 0.0022 17.4 4.1 3.6 7.0 0.1 3.9 4 0 0 4 4 4 2 Signal recognition particle receptor beta subunit MobB PF03205.14 CCC71755.1 - 0.0034 17.3 1.5 0.0056 16.6 0.0 2.2 3 0 0 3 3 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.12 CCC71755.1 - 0.013 14.8 0.0 0.064 12.5 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 CCC71755.1 - 0.015 15.1 0.1 0.052 13.3 0.1 1.9 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein APS_kinase PF01583.20 CCC71755.1 - 0.017 15.0 0.3 0.039 13.9 0.0 1.7 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_18 PF13238.6 CCC71755.1 - 0.021 15.4 0.0 0.066 13.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.6 CCC71755.1 - 0.022 15.0 0.2 0.11 12.7 0.2 2.4 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.6 CCC71755.1 - 0.023 14.6 1.6 0.037 13.9 0.1 2.2 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 CCC71755.1 - 0.026 13.5 1.6 0.061 12.3 0.0 2.4 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_16 PF13191.6 CCC71755.1 - 0.029 14.8 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 CCC71755.1 - 0.03 14.0 0.0 0.11 12.3 0.0 2.0 2 0 0 2 2 1 0 AAA domain VirE PF05272.11 CCC71755.1 - 0.059 13.1 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Virulence-associated protein E AAA_24 PF13479.6 CCC71755.1 - 0.063 13.0 1.4 0.25 11.0 0.1 2.5 3 0 0 3 3 3 0 AAA domain KTI12 PF08433.10 CCC71755.1 - 0.067 12.6 0.5 1.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_28 PF13521.6 CCC71755.1 - 0.18 12.0 0.0 0.57 10.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 CCC71755.1 - 0.18 11.9 1.0 0.98 9.5 0.1 2.7 3 1 0 3 3 3 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 CCC71755.1 - 0.35 10.8 3.4 0.55 10.1 0.2 2.7 2 1 1 3 3 3 0 NTPase Snapin_Pallidin PF14712.6 CCC71755.1 - 0.83 10.1 4.4 0.2 12.1 0.4 2.1 2 0 0 2 2 1 0 Snapin/Pallidin AAA PF00004.29 CCC71755.1 - 1.6 9.2 4.4 2.5 8.5 0.9 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TFIIB PF00382.19 CCC71756.1 - 4.6e-43 145.1 2.5 1.4e-27 95.5 1.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 CCC71756.1 - 1.5e-13 50.0 0.7 3e-13 49.0 0.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding zf-ribbon_3 PF13248.6 CCC71756.1 - 0.13 11.7 0.5 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 zinc-ribbon domain RecO_N PF11967.8 CCC71756.1 - 0.16 12.0 0.1 0.33 11.0 0.1 1.5 1 0 0 1 1 1 0 Recombination protein O N terminal Atg14 PF10186.9 CCC71757.1 - 6.2e-17 61.7 13.2 2.6e-16 59.6 13.2 1.9 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 zf-C4pol PF14260.6 CCC71757.1 - 0.032 14.7 1.1 0.032 14.7 1.1 2.5 3 0 0 3 3 3 0 C4-type zinc-finger of DNA polymerase delta PMBR PF09373.10 CCC71757.1 - 0.086 13.0 0.9 6.8 7.0 0.0 3.3 4 0 0 4 4 4 0 Pseudomurein-binding repeat DUF2508 PF10704.9 CCC71757.1 - 5.5 7.2 10.6 7.1 6.9 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2508) SHE3 PF17078.5 CCC71758.1 - 5.4e-27 95.0 23.4 5.4e-27 95.0 23.4 1.8 1 1 0 1 1 1 1 SWI5-dependent HO expression protein 3 Ndc1_Nup PF09531.10 CCC71758.1 - 0.15 10.7 7.0 0.016 13.9 2.7 1.4 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF4699 PF15770.5 CCC71758.1 - 1.8 8.3 9.3 0.21 11.3 4.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4699) PH PF00169.29 CCC71759.1 - 4.6e-08 33.5 5.3 0.00076 20.0 0.2 2.9 2 2 1 3 3 3 2 PH domain PH_11 PF15413.6 CCC71759.1 - 0.28 11.6 10.3 5 7.6 3.0 3.7 2 2 1 3 3 3 0 Pleckstrin homology domain ATP-synt_ab PF00006.25 CCC71760.1 - 4.3e-66 222.6 0.0 6.1e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 CCC71760.1 - 1.8e-15 57.2 0.9 3.8e-15 56.2 0.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF3533 PF12051.8 CCC71760.1 - 0.038 12.9 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) HAS-barrel PF09378.10 CCC71760.1 - 0.17 12.1 0.6 0.47 10.6 0.3 1.9 2 0 0 2 2 2 0 HAS barrel domain Glyco_transf_20 PF00982.21 CCC71761.1 - 5.3e-202 671.7 0.0 6.1e-202 671.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.20 CCC71761.1 - 0.0057 16.2 2.9 0.4 10.2 0.1 3.2 3 1 0 3 3 3 2 Glycosyl transferases group 1 PP2C PF00481.21 CCC71762.1 - 2.8e-65 220.5 0.0 9.9e-64 215.4 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 CCC71762.1 - 0.02 14.8 0.0 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Tau95 PF09734.9 CCC71763.1 - 1e-33 117.1 1.2 1.8e-33 116.3 1.2 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 CCC71763.1 - 5.9e-26 91.1 0.1 1.2e-25 90.2 0.1 1.5 1 0 0 1 1 1 1 Tau95 Triple barrel domain Ribosomal_L31 PF01197.18 CCC71764.1 - 0.021 15.1 0.0 0.052 13.8 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L31 Bac_A_amyl_C PF18612.1 CCC71764.1 - 0.083 12.7 0.0 0.49 10.2 0.0 2.2 3 0 0 3 3 3 0 Bacterial Alpha amylase C-terminal domain HGTP_anticodon PF03129.20 CCC71765.1 - 5.8e-23 80.9 0.6 1.9e-22 79.2 0.1 2.2 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2b PF00587.25 CCC71765.1 - 7.9e-07 29.2 0.0 2.3e-06 27.7 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) DUF5063 PF16702.5 CCC71766.1 - 0.042 14.2 0.0 0.063 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5063) TssO PF17561.2 CCC71766.1 - 0.57 10.3 5.6 1.3 9.1 5.6 1.7 1 1 0 1 1 1 0 Type VI secretion system, TssO RRM_1 PF00076.22 CCC71767.1 - 1.4e-10 40.8 0.1 4.7e-05 23.1 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trans_reg_C PF00486.28 CCC71767.1 - 0.045 13.8 0.7 0.092 12.8 0.7 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal DUF3343 PF11823.8 CCC71767.1 - 0.48 9.9 2.5 1.4 8.4 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3343) GTP_EFTU PF00009.27 CCC71768.1 - 1e-54 185.0 0.0 1.5e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 CCC71768.1 - 3.4e-40 136.8 0.0 7.2e-40 135.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 CCC71768.1 - 6.4e-15 55.3 3.8 7.3e-15 55.1 1.7 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 CCC71768.1 - 0.00029 20.9 0.1 0.0067 16.5 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 CCC71768.1 - 0.045 13.6 0.9 0.045 13.6 0.9 1.9 2 0 0 2 2 2 0 Elongation factor Tu domain 4 CIMR PF00878.18 CCC71769.1 - 8.7e-09 35.6 1.4 5e-05 23.4 0.1 3.2 3 0 0 3 3 3 3 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.6 CCC71769.1 - 0.00011 22.0 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Man-6-P_recep PF02157.15 CCC71769.1 - 0.00024 20.3 0.0 0.00038 19.6 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Metallothio_5 PF02067.15 CCC71770.1 - 6.8 6.9 57.3 0.51 10.5 25.5 2.1 2 0 0 2 2 2 0 Metallothionein family 5 Transketolase_N PF00456.21 CCC71771.1 - 1.7e-156 520.4 0.0 4.6e-156 518.9 0.0 1.6 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 CCC71771.1 - 1.1e-45 155.5 0.0 1.7e-45 154.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 CCC71771.1 - 3.9e-12 46.1 0.0 7.6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.6 CCC71771.1 - 2e-05 24.0 0.1 9e-05 21.8 0.1 2.0 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.20 CCC71771.1 - 0.00022 20.3 0.0 0.0016 17.5 0.0 2.1 2 0 0 2 2 2 1 Dehydrogenase E1 component Terpene_synth PF01397.21 CCC71771.1 - 0.19 11.4 0.0 0.44 10.2 0.0 1.5 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain NAD_binding_4 PF07993.12 CCC71772.1 - 3.9e-71 239.2 0.0 5.8e-71 238.7 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.28 CCC71772.1 - 3.8e-65 220.1 0.0 5.1e-65 219.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme PP-binding PF00550.25 CCC71772.1 - 1.5e-13 50.8 0.0 4.1e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.21 CCC71772.1 - 7.7e-10 38.6 0.0 1.3e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 CCC71772.1 - 3.8e-06 26.1 0.0 1e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.6 CCC71772.1 - 0.00058 20.8 0.0 0.0026 18.7 0.0 2.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Condensation PF00668.20 CCC71772.1 - 0.0017 17.2 8.0 0.056 12.1 1.9 2.9 1 1 2 3 3 3 2 Condensation domain NAD_binding_10 PF13460.6 CCC71772.1 - 0.0036 17.2 0.0 0.013 15.4 0.0 2.0 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 CCC71772.1 - 0.02 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family GDP_Man_Dehyd PF16363.5 CCC71772.1 - 0.045 13.2 0.1 0.076 12.4 0.1 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 CCC71772.1 - 0.073 12.2 0.0 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein SNF2_N PF00176.23 CCC71773.1 - 1.2e-54 185.3 1.0 3.9e-54 183.7 0.7 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCC71773.1 - 9.3e-16 58.2 0.0 3.2e-14 53.2 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC71773.1 - 1.1e-09 38.5 0.2 2.9e-09 37.2 0.2 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4 PF00097.25 CCC71773.1 - 1e-08 34.9 10.7 1e-08 34.9 10.7 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 CCC71773.1 - 1.8e-08 34.3 0.1 3.7e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_2 PF13923.6 CCC71773.1 - 4.3e-05 23.3 9.3 4.3e-05 23.3 9.3 2.6 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCC71773.1 - 4.4e-05 23.5 9.2 4.4e-05 23.5 9.2 2.3 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 CCC71773.1 - 0.00069 19.6 5.3 0.00069 19.6 5.3 1.9 2 0 0 2 2 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 CCC71773.1 - 0.0022 18.3 9.7 0.0022 18.3 9.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCC71773.1 - 0.0087 15.9 7.8 0.0087 15.9 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) MH2 PF03166.14 CCC71773.1 - 0.0087 16.3 0.3 0.037 14.3 0.0 2.2 2 0 0 2 2 2 1 MH2 domain zf-Nse PF11789.8 CCC71773.1 - 0.011 15.5 5.7 0.034 14.0 5.7 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 CCC71773.1 - 0.019 15.3 5.6 0.019 15.3 5.6 2.1 2 0 0 2 2 1 0 RING-H2 zinc finger domain Zn_Tnp_IS91 PF14319.6 CCC71773.1 - 0.019 15.0 15.2 0.022 14.8 3.5 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_6 PF14835.6 CCC71773.1 - 0.028 14.3 2.1 0.077 12.9 2.1 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Nop14 PF04147.12 CCC71773.1 - 0.18 10.0 14.1 0.26 9.5 14.1 1.1 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 CCC71773.1 - 0.82 9.0 18.3 1.4 8.3 18.3 1.3 1 0 0 1 1 1 0 SDA1 zf-ANAPC11 PF12861.7 CCC71773.1 - 6.6 6.9 9.7 0.19 11.8 1.9 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 CCC71773.1 - 7.2 6.6 19.1 0.026 14.4 8.0 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 EnY2 PF10163.9 CCC71774.1 - 2.9e-24 85.2 2.6 3.3e-24 85.0 2.6 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 NUDIX PF00293.28 CCC71775.1 - 6.5e-16 58.6 0.0 3.5e-15 56.2 0.0 1.9 2 0 0 2 2 2 1 NUDIX domain Spermine_synth PF01564.17 CCC71776.1 - 1.1e-75 253.3 0.1 1.4e-75 252.8 0.1 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 CCC71776.1 - 1.7e-26 91.9 0.1 3e-26 91.1 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 CCC71776.1 - 0.00025 21.7 0.0 0.00054 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 CCC71776.1 - 0.0024 18.6 0.1 0.0089 16.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.16 CCC71776.1 - 0.0056 15.9 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Branched-chain polyamine synthase A C-terminal domain Methyltransf_18 PF12847.7 CCC71776.1 - 0.034 14.1 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Glycos_transf_1 PF00534.20 CCC71777.1 - 2.5e-09 36.9 0.0 3.9e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 CCC71777.1 - 6.5e-06 26.6 0.0 9.9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 CCC71777.1 - 0.00011 22.5 0.0 0.00021 21.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 CCC71777.1 - 0.0094 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 EF-hand_1 PF00036.32 CCC71778.1 - 3.6e-31 104.4 3.7 1.4e-08 33.7 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 CCC71778.1 - 2.4e-27 95.2 0.2 1.6e-14 54.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 CCC71778.1 - 2.5e-26 89.3 3.0 5.5e-08 32.1 0.0 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 CCC71778.1 - 2.2e-18 64.8 3.6 4.9e-07 29.0 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 CCC71778.1 - 1.7e-16 59.8 5.1 2.1e-08 33.9 0.0 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 CCC71778.1 - 1.1e-12 48.1 0.0 1.3e-08 35.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 CCC71778.1 - 1.5e-06 28.5 0.1 0.0012 19.1 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 CCC71778.1 - 1.3e-05 25.5 0.1 0.23 11.8 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 CCC71778.1 - 8.9e-05 22.4 0.0 0.064 13.3 0.0 3.0 3 0 0 3 3 3 1 Uncharacterised protein family (UPF0154) Caleosin PF05042.13 CCC71778.1 - 0.0012 18.8 0.0 0.84 9.5 0.0 3.0 1 1 2 3 3 3 1 Caleosin related protein Dockerin_1 PF00404.18 CCC71778.1 - 0.0015 18.7 0.4 0.63 10.3 0.1 2.6 1 1 1 2 2 2 2 Dockerin type I domain EF-hand_4 PF12763.7 CCC71778.1 - 0.0021 18.0 0.3 0.0064 16.4 0.1 1.8 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 CCC71778.1 - 0.0059 16.6 0.2 0.13 12.2 0.0 2.2 2 1 0 2 2 2 1 Tellurite resistance protein TerB SurA_N_3 PF13624.6 CCC71778.1 - 0.01 15.6 0.5 0.39 10.5 0.2 2.0 1 1 1 2 2 2 0 SurA N-terminal domain DUF853 PF05872.12 CCC71778.1 - 0.014 14.0 0.2 0.052 12.1 0.1 1.6 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_assoc_C PF09821.9 CCC71778.1 - 0.05 14.1 1.0 6 7.4 0.2 2.9 2 1 1 3 3 3 0 C-terminal AAA-associated domain RNA_pol_Rpb4 PF03874.16 CCC71778.1 - 0.056 13.8 0.7 0.7 10.2 0.1 2.4 2 1 1 3 3 3 0 RNA polymerase Rpb4 GPHH PF16905.5 CCC71778.1 - 0.075 12.8 0.0 0.87 9.4 0.0 2.3 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated DUF4497 PF14924.6 CCC71778.1 - 0.083 13.4 0.0 8.5 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Glycos_trans_3N PF02885.17 CCC71778.1 - 0.16 11.8 4.1 3.3 7.6 0.1 3.4 1 1 2 3 3 3 0 Glycosyl transferase family, helical bundle domain AIM3 PF17096.5 CCC71779.1 - 1.7e-32 112.2 13.2 1.7e-32 112.2 13.2 7.9 7 2 0 7 7 7 1 Altered inheritance of mitochondria protein 3 Fe-S_biosyn PF01521.20 CCC71780.1 - 1.7e-15 57.2 0.1 8.3e-14 51.7 0.1 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3851 PF12962.7 CCC71780.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3851) Pho88 PF10032.9 CCC71781.1 - 2.2e-66 222.6 1.0 2.7e-66 222.3 1.0 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) Baculo_VP1054 PF05789.11 CCC71781.1 - 0.013 14.8 0.2 0.016 14.4 0.2 1.1 1 0 0 1 1 1 0 Baculovirus VP1054 protein DUF2871 PF11070.8 CCC71781.1 - 0.04 14.2 1.6 0.04 14.2 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) Vac_ImportDeg PF09783.9 CCC71782.1 - 1.3e-56 190.9 4.5 1.8e-56 190.4 4.5 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mito_carr PF00153.27 CCC71783.1 - 5e-59 196.2 0.4 4.4e-20 71.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.26 CCC71784.1 - 0.0054 17.1 7.2 0.85 10.2 0.2 2.9 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC71784.1 - 0.16 12.9 5.2 9.1 7.4 0.3 3.0 1 1 2 3 3 3 0 C2H2-type zinc finger Exo84_C PF16528.5 CCC71786.1 - 1.2e-68 230.9 11.9 1.2e-68 230.9 11.9 2.3 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 CCC71786.1 - 2.9e-10 40.1 2.6 2.9e-10 40.1 2.6 3.2 3 0 0 3 3 3 1 Vps51/Vps67 COG2 PF06148.11 CCC71786.1 - 1.3e-05 25.3 1.7 1.3e-05 25.3 1.7 3.5 5 0 0 5 5 5 2 COG (conserved oligomeric Golgi) complex component, COG2 EspB PF05802.11 CCC71786.1 - 0.015 15.3 0.2 1.2 9.1 0.1 2.8 2 0 0 2 2 2 0 Enterobacterial EspB protein UPF0515 PF15135.6 CCC71786.1 - 0.033 13.5 3.3 0.11 11.8 3.3 1.9 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 Synaptonemal_3 PF15191.6 CCC71786.1 - 1.4 8.8 5.3 1.3 8.9 0.3 2.7 2 0 0 2 2 2 0 Synaptonemal complex central element protein 3 DUF5601 PF18151.1 CCC71786.1 - 7.1 7.0 7.0 2.2 8.6 0.4 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF5601) Fes1 PF08609.10 CCC71787.1 - 1e-21 77.6 1.9 1.7e-20 73.7 0.3 3.0 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.23 CCC71787.1 - 0.00041 20.3 0.0 0.013 15.5 0.0 3.1 3 1 0 3 3 3 1 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.8 CCC71787.1 - 0.0066 16.6 2.1 0.017 15.2 1.1 2.1 1 1 1 2 2 2 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 CCC71787.1 - 0.009 16.0 1.6 0.35 10.9 0.2 2.8 2 1 1 3 3 3 2 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 CCC71787.1 - 0.017 15.1 5.8 0.047 13.6 0.2 2.7 1 1 3 4 4 4 0 Domain of unknown function (DUF3361) IBN_N PF03810.19 CCC71787.1 - 0.017 15.0 0.6 0.19 11.7 0.2 2.6 2 2 0 2 2 2 0 Importin-beta N-terminal domain DUF4042 PF13251.6 CCC71787.1 - 0.037 13.7 0.5 0.92 9.2 0.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4042) HEAT_EZ PF13513.6 CCC71787.1 - 0.076 13.5 0.0 0.51 10.9 0.0 2.4 2 0 0 2 2 2 0 HEAT-like repeat RICTOR_V PF14668.6 CCC71787.1 - 0.099 12.9 0.0 0.41 10.9 0.0 2.0 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT PF02985.22 CCC71787.1 - 0.12 12.7 0.0 0.58 10.6 0.0 2.3 1 0 0 1 1 1 0 HEAT repeat ERCC4 PF02732.15 CCC71788.1 - 1.7e-16 60.8 3.9 1.7e-16 60.8 3.9 2.4 1 1 1 2 2 2 1 ERCC4 domain Rbsn PF11464.8 CCC71788.1 - 0.13 12.0 1.3 0.23 11.2 0.3 2.0 2 0 0 2 2 2 0 Rabenosyn Rab binding domain EstA_Ig_like PF18435.1 CCC71788.1 - 0.29 11.3 1.2 6.2 7.0 0.4 2.7 2 0 0 2 2 2 0 Esterase Ig-like N-terminal domain OmpH PF03938.14 CCC71788.1 - 8.4 6.7 10.9 2 8.8 2.4 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) Pkinase PF00069.25 CCC71789.1 - 3.4e-25 88.9 0.1 6.6e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71789.1 - 1.8e-11 43.8 0.0 3.1e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 CCC71789.1 - 3.1e-10 39.4 4.2 0.91 10.0 0.0 6.0 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 CCC71789.1 - 2e-06 28.1 0.0 0.18 12.2 0.0 3.1 3 1 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 CCC71789.1 - 0.0002 21.8 0.1 7.8 7.1 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat Cnd1 PF12717.7 CCC71789.1 - 0.0033 17.5 2.8 1.4 8.9 0.1 3.2 1 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 WD40 PF00400.32 CCC71789.1 - 0.0036 18.1 0.0 3.5 8.7 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat Kdo PF06293.14 CCC71789.1 - 0.062 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RasGEF_N_2 PF14663.6 CCC71789.1 - 0.074 13.5 1.8 1.5 9.3 0.1 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Vac14_Fab1_bd PF12755.7 CCC71789.1 - 0.12 13.0 0.4 2 9.1 0.0 2.8 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region 4HBT_2 PF13279.6 CCC71790.1 - 8.8e-09 35.9 0.0 1.2e-08 35.4 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily KH_1 PF00013.29 CCC71790.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 KH domain RXT2_N PF08595.11 CCC71791.1 - 1.3e-33 116.2 12.0 2e-33 115.6 3.7 2.5 2 0 0 2 2 2 2 RXT2-like, N-terminal TTL PF03133.15 CCC71792.1 - 9.9e-78 261.2 5.2 1.5e-77 260.7 5.2 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.17 CCC71792.1 - 2.9e-46 157.7 0.0 5.7e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.6 CCC71792.1 - 0.00019 20.8 0.1 0.041 13.1 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp Herpes_BLLF1 PF05109.13 CCC71792.1 - 0.017 13.1 0.1 0.025 12.6 0.1 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) zf-Tim10_DDP PF02953.15 CCC71793.1 - 3.6e-13 49.0 0.9 4.8e-13 48.5 0.9 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger HMG_box PF00505.19 CCC71794.1 - 1.1e-22 80.2 0.2 1.6e-22 79.7 0.2 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 CCC71794.1 - 8.5e-18 64.7 0.1 1.2e-17 64.3 0.1 1.2 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.12 CCC71794.1 - 0.0062 16.5 0.0 0.0098 15.8 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain PCNA_N PF00705.18 CCC71795.1 - 7.9e-55 184.0 1.6 1.4e-54 183.2 1.6 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 CCC71795.1 - 5.3e-49 165.7 0.0 1.5e-48 164.2 0.1 1.7 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 CCC71795.1 - 4.4e-07 29.3 0.4 2.7e-06 26.7 0.4 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 CCC71795.1 - 0.01 15.3 0.1 0.012 15.1 0.1 1.2 1 0 0 1 1 1 0 Rad9 FOP_dimer PF09398.10 CCC71795.1 - 0.11 12.8 0.1 0.27 11.5 0.1 1.7 1 0 0 1 1 1 0 FOP N terminal dimerisation domain FAD_binding_1 PF00667.20 CCC71796.1 - 4e-30 105.1 0.0 1e-29 103.7 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 CCC71796.1 - 8.3e-25 87.7 0.0 1.6e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 CCC71796.1 - 3.1e-11 43.9 0.0 7.1e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.7 CCC71796.1 - 0.052 13.2 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Flavodoxin domain Ala_racemase_N PF01168.20 CCC71797.1 - 8.2e-22 77.9 0.0 1e-21 77.6 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF4268 PF14088.6 CCC71797.1 - 0.29 11.0 2.9 2.5 8.0 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4268) Anoctamin PF04547.12 CCC71798.1 - 7e-37 127.3 38.0 1.4e-36 126.3 38.0 1.4 1 1 0 1 1 1 1 Calcium-activated chloride channel KH_1 PF00013.29 CCC71800.1 - 3.1e-24 84.6 4.7 5.3e-10 39.0 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 CCC71800.1 - 0.0046 16.7 4.7 6.3 6.7 0.3 3.8 3 2 0 3 3 3 2 KH domain KH_5 PF13184.6 CCC71800.1 - 0.043 13.9 0.5 9 6.5 0.0 2.8 3 0 0 3 3 3 0 NusA-like KH domain MOEP19 PF16005.5 CCC71800.1 - 0.05 13.6 0.1 0.53 10.3 0.1 2.3 2 0 0 2 2 2 0 KH-like RNA-binding domain Cellulase-like PF12876.7 CCC71800.1 - 0.069 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Sugar-binding cellulase-like FtsJ PF01728.19 CCC71800.1 - 0.14 12.2 0.1 0.25 11.4 0.1 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Mito_carr PF00153.27 CCC71801.1 - 6.6e-69 227.9 7.3 2.6e-25 88.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 CCC71801.1 - 0.17 11.0 0.1 0.67 9.1 0.1 1.8 2 0 0 2 2 2 0 Fuseless Ribosomal_L19e PF01280.20 CCC71802.1 - 6e-58 195.0 8.7 6e-58 195.0 8.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e FTHFS PF01268.19 CCC71803.1 - 2.1e-250 831.7 0.5 2.8e-250 831.3 0.5 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.19 CCC71803.1 - 6.5e-69 230.3 0.2 6.5e-69 230.3 0.2 2.0 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 CCC71803.1 - 3.6e-36 124.0 0.3 1.1e-35 122.4 0.3 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain TEA PF01285.18 CCC71804.1 - 2.5e-26 91.5 0.1 5.7e-26 90.4 0.1 1.7 1 0 0 1 1 1 1 TEA/ATTS domain CBF PF03914.17 CCC71805.1 - 1.9e-47 161.5 0.0 1.9e-47 161.5 0.0 3.4 4 1 0 4 4 4 1 CBF/Mak21 family Cnd1 PF12717.7 CCC71805.1 - 0.0058 16.7 2.5 0.0086 16.1 0.5 2.3 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Bromodomain PF00439.25 CCC71806.1 - 7e-16 58.1 0.6 2.8e-15 56.2 0.6 2.1 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.13 CCC71806.1 - 9.7e-07 28.7 0.0 2.5e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated Bromo_TP_like PF17027.5 CCC71806.1 - 0.0054 16.9 1.9 0.037 14.2 0.1 3.3 2 0 0 2 2 2 1 Histone-fold protein RNA_pol_A_bac PF01000.26 CCC71806.1 - 0.32 11.4 6.6 1.3 9.5 0.7 3.8 2 1 1 3 3 3 0 RNA polymerase Rpb3/RpoA insert domain AAA PF00004.29 CCC71808.1 - 1.3e-51 174.5 0.0 5.9e-38 130.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 CCC71808.1 - 2e-10 40.3 0.8 9.2e-10 38.2 0.1 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_lid_3 PF17862.1 CCC71808.1 - 2.6e-10 39.9 0.1 1.6e-09 37.4 0.1 2.2 1 1 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 CCC71808.1 - 5.7e-10 39.6 0.1 0.00023 21.5 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.6 CCC71808.1 - 2.1e-08 34.8 0.1 0.0011 19.3 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain CDC48_N PF02359.18 CCC71808.1 - 3.1e-08 33.7 0.0 1.1e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain TIP49 PF06068.13 CCC71808.1 - 1.6e-07 30.9 0.0 0.0037 16.5 0.0 2.3 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 CCC71808.1 - 2.7e-07 30.7 0.1 0.0027 17.7 0.0 3.3 3 0 0 3 3 2 2 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 CCC71808.1 - 2.8e-07 30.1 0.2 0.0025 17.2 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 CCC71808.1 - 3e-07 30.7 0.0 0.0031 17.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 CCC71808.1 - 1.3e-06 28.2 0.3 0.066 13.0 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 CCC71808.1 - 4.2e-06 26.6 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein PhoH PF02562.16 CCC71808.1 - 6.4e-06 25.8 0.0 0.011 15.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_18 PF13238.6 CCC71808.1 - 1.6e-05 25.5 0.0 0.46 11.0 0.0 3.1 2 1 1 3 3 3 2 AAA domain RNA_helicase PF00910.22 CCC71808.1 - 1.8e-05 25.0 0.1 0.59 10.5 0.0 3.4 3 0 0 3 3 3 2 RNA helicase NACHT PF05729.12 CCC71808.1 - 2.5e-05 24.2 1.3 0.058 13.3 0.0 3.6 4 0 0 4 4 3 1 NACHT domain AAA_2 PF07724.14 CCC71808.1 - 3.9e-05 23.8 0.0 0.0031 17.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ABC_tran PF00005.27 CCC71808.1 - 4.6e-05 23.9 0.2 0.068 13.7 0.1 2.6 2 0 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 CCC71808.1 - 9.1e-05 22.3 0.1 0.68 9.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_11 PF13086.6 CCC71808.1 - 0.00011 22.1 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 CCC71808.1 - 0.00029 20.6 0.0 0.46 10.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 CCC71808.1 - 0.00034 19.9 0.0 0.084 12.0 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_23 PF13476.6 CCC71808.1 - 0.00068 20.2 1.0 0.65 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 CCC71808.1 - 0.00071 18.9 0.0 1.1 8.4 0.0 2.4 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_7 PF12775.7 CCC71808.1 - 0.001 18.6 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_30 PF13604.6 CCC71808.1 - 0.0012 18.6 0.1 1.3 8.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 CCC71808.1 - 0.0016 18.4 0.0 1.6 8.7 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 CCC71808.1 - 0.0017 18.4 0.0 2.2 8.3 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TniB PF05621.11 CCC71808.1 - 0.0019 17.6 0.4 4.9 6.5 0.0 3.6 3 1 0 3 3 3 0 Bacterial TniB protein AAA_19 PF13245.6 CCC71808.1 - 0.0021 18.4 0.1 1.1 9.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 CCC71808.1 - 0.0021 17.4 0.2 0.53 9.6 0.1 2.6 2 0 0 2 2 2 1 KaiC AAA_28 PF13521.6 CCC71808.1 - 0.0035 17.6 0.0 3.5 7.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 CCC71808.1 - 0.0038 17.1 0.0 0.56 10.1 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 CCC71808.1 - 0.0086 16.5 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 CCC71808.1 - 0.012 15.2 2.2 2.7 7.5 0.2 3.0 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 CCC71808.1 - 0.015 14.6 0.0 0.5 9.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.6 CCC71808.1 - 0.031 14.0 0.1 2.6 7.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain Bac_DnaA PF00308.18 CCC71808.1 - 0.04 13.8 0.0 3.1 7.6 0.0 2.8 3 0 0 3 3 3 0 Bacterial dnaA protein Rad17 PF03215.15 CCC71808.1 - 0.042 13.8 0.2 9.6 6.1 0.0 3.2 3 1 0 3 3 2 0 Rad17 P-loop domain Parvo_NS1 PF01057.17 CCC71808.1 - 0.044 12.9 0.0 9 5.3 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 ATPase_2 PF01637.18 CCC71808.1 - 0.045 13.7 0.2 4.3 7.2 0.0 3.1 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea T2SSE PF00437.20 CCC71808.1 - 0.056 12.5 0.0 8.5 5.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein NTPase_1 PF03266.15 CCC71808.1 - 0.06 13.3 0.1 9.1 6.2 0.0 2.6 2 0 0 2 2 2 0 NTPase cobW PF02492.19 CCC71808.1 - 0.13 11.9 0.3 3.7 7.1 0.0 2.9 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.29 CCC71808.1 - 0.15 11.8 0.1 42 3.8 0.0 3.6 3 1 1 4 4 4 0 DEAD/DEAH box helicase PCI PF01399.27 CCC71809.1 - 9.4e-08 32.5 0.4 9.4e-08 32.5 0.4 3.3 3 0 0 3 3 3 1 PCI domain PAF-AH_p_II PF03403.13 CCC71809.1 - 0.11 11.0 6.6 0.043 12.3 3.0 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Recep_L_domain PF01030.24 CCC71810.1 - 2.9e-09 37.0 8.2 0.0095 16.1 0.1 4.7 1 1 4 5 5 5 4 Receptor L domain Ecm33 PF12454.8 CCC71810.1 - 0.13 12.4 3.8 0.58 10.4 3.8 2.2 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein UQ_con PF00179.26 CCC71811.1 - 2.1e-43 147.3 0.3 2.8e-43 146.9 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 CCC71811.1 - 0.0019 17.9 0.1 0.0075 16.0 0.0 2.0 1 1 0 1 1 1 1 Prokaryotic E2 family B TSGP1 PF07771.11 CCC71811.1 - 0.019 15.1 0.2 0.036 14.2 0.2 1.4 1 0 0 1 1 1 0 Tick salivary peptide group 1 CAF1-p150_C2 PF15539.6 CCC71811.1 - 0.26 10.7 3.0 0.43 10.0 3.0 1.3 1 0 0 1 1 1 0 CAF1 complex subunit p150, region binding to CAF1-p60 at C-term SLM4 PF16818.5 CCC71812.1 - 1.1e-66 223.8 6.0 1.3e-66 223.5 6.0 1.1 1 0 0 1 1 1 1 Protein SLM4 Dfp1_Him1_M PF08630.10 CCC71813.1 - 1.1e-17 64.4 3.3 2.4e-14 53.7 0.1 2.9 2 1 1 3 3 3 2 Dfp1/Him1, central region POT1PC PF16686.5 CCC71813.1 - 0.046 13.6 0.4 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 ssDNA-binding domain of telomere protection protein zf-C2H2 PF00096.26 CCC71814.1 - 6.7e-10 38.9 8.0 0.00031 21.0 2.6 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC71814.1 - 1.4e-06 28.6 6.9 0.022 15.6 0.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCC71814.1 - 0.001 19.4 1.6 0.067 13.6 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCC71814.1 - 0.024 14.9 0.5 0.1 12.9 0.0 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.6 CCC71814.1 - 0.034 14.6 9.2 0.044 14.2 0.2 2.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_6 PF13912.6 CCC71814.1 - 0.08 13.0 0.1 0.08 13.0 0.1 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger Zn_ribbon_SprT PF17283.2 CCC71814.1 - 0.31 11.0 2.2 0.6 10.1 2.2 1.4 1 0 0 1 1 1 0 SprT-like zinc ribbon domain DUF4451 PF14616.6 CCC71816.1 - 5.6e-06 26.6 1.9 5.6e-06 26.6 1.9 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4451) TPR_2 PF07719.17 CCC71817.1 - 8.6e-17 59.8 5.5 0.00031 20.6 0.1 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 CCC71817.1 - 5.9e-15 54.4 8.4 0.0069 16.2 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 CCC71817.1 - 4.7e-11 42.0 11.8 0.0027 17.8 0.1 6.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCC71817.1 - 1.6e-09 37.8 1.1 0.072 14.0 0.0 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCC71817.1 - 4.5e-09 36.7 4.4 0.58 10.7 0.0 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 CCC71817.1 - 6.5e-08 32.8 6.4 0.0057 16.9 0.0 4.8 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 CCC71817.1 - 4.5e-07 29.8 13.4 0.0062 16.8 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 CCC71817.1 - 2.3e-06 27.2 1.6 1.5 9.1 0.0 5.4 6 0 0 6 6 5 2 Tetratricopeptide repeat ANAPC5 PF12862.7 CCC71817.1 - 2.4e-06 27.5 2.9 0.0039 17.2 0.3 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 5 DUF3856 PF12968.7 CCC71817.1 - 1.5e-05 25.1 0.1 0.00067 19.7 0.0 2.8 3 0 0 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_11 PF13414.6 CCC71817.1 - 2e-05 24.1 6.3 0.02 14.5 0.0 4.4 5 0 0 5 5 5 2 TPR repeat TPR_16 PF13432.6 CCC71817.1 - 0.00016 22.2 1.6 7.7 7.3 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 CCC71817.1 - 0.00032 21.1 2.5 1e+02 3.9 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.9 CCC71817.1 - 0.00097 18.9 0.1 6.1 6.5 0.0 3.2 2 1 0 3 3 3 2 26S proteasome subunit RPN7 TPR_15 PF13429.6 CCC71817.1 - 0.0017 17.6 1.2 18 4.4 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 CCC71817.1 - 0.0064 16.3 2.2 24 5.0 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.10 CCC71817.1 - 0.017 14.1 8.1 4 6.3 0.0 4.1 3 2 0 4 4 4 0 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 CCC71817.1 - 0.02 15.1 9.6 0.87 9.9 0.8 4.8 4 2 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 SNF2_N PF00176.23 CCC71819.1 - 4.6e-61 206.5 0.0 9.3e-61 205.5 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 CCC71819.1 - 2.8e-16 59.8 0.1 1e-15 58.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC71819.1 - 8.4e-11 42.2 0.0 8.4e-11 42.2 0.0 3.0 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit DUF2439 PF10382.9 CCC71819.1 - 0.0001 22.6 0.1 0.00042 20.6 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) AAA_22 PF13401.6 CCC71819.1 - 0.0018 18.6 0.1 1.2 9.4 0.1 3.0 2 1 0 2 2 2 2 AAA domain DUF4460 PF14687.6 CCC71819.1 - 0.037 14.1 0.0 0.15 12.1 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4460) AA_permease PF00324.21 CCC71820.1 - 3.5e-124 415.0 33.9 4e-124 414.8 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC71820.1 - 2.4e-36 125.5 33.7 2.9e-36 125.2 33.7 1.0 1 0 0 1 1 1 1 Amino acid permease Pet100 PF09803.9 CCC71820.1 - 0.096 13.2 0.0 0.42 11.2 0.0 1.9 2 0 0 2 2 2 0 Pet100 AA_permease PF00324.21 CCC71821.1 - 6.4e-130 433.9 37.7 8.1e-130 433.6 37.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC71821.1 - 9.8e-37 126.8 37.4 1.3e-36 126.4 37.4 1.1 1 0 0 1 1 1 1 Amino acid permease Abhydrolase_9_N PF15420.6 CCC71821.1 - 0.16 12.0 2.4 0.15 12.1 0.2 2.1 2 0 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus SRP1_TIP1 PF00660.17 CCC71822.1 - 6.6e-35 119.1 0.4 1.6e-34 117.9 0.4 1.6 1 0 0 1 1 1 1 Seripauperin and TIP1 family PIR PF00399.19 CCC71822.1 - 4.2e-07 29.4 6.3 4.2e-07 29.4 6.3 3.6 3 0 0 3 3 3 1 Yeast PIR protein repeat FAM199X PF15814.5 CCC71822.1 - 2.1 7.3 15.5 2.4 7.2 15.3 1.3 1 1 0 1 1 1 0 Protein family FAM199X zf-H2C2_2 PF13465.6 CCC71824.1 - 5.4e-05 23.4 2.8 5.4e-05 23.4 2.8 3.4 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.26 CCC71824.1 - 0.00028 21.2 18.3 0.0023 18.3 3.3 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC71824.1 - 0.0087 16.8 14.9 0.079 13.8 2.0 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.7 CCC71824.1 - 0.57 10.6 8.8 0.58 10.6 1.0 3.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF4701 PF15773.5 CCC71826.1 - 0.12 11.3 1.0 0.16 10.9 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4701) FtsJ PF01728.19 CCC71827.1 - 6.2e-66 221.9 0.1 8e-66 221.5 0.1 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 CCC71827.1 - 0.038 13.8 0.0 0.058 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ORC2 PF04084.14 CCC71828.1 - 2.9e-106 355.1 1.8 4e-106 354.7 1.8 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.19 CCC71828.1 - 2.4e-06 26.8 42.8 0.069 13.0 3.0 5.0 4 0 0 4 4 4 4 AT hook motif UCH PF00443.29 CCC71830.1 - 7.4e-47 160.0 0.8 7.4e-47 160.0 0.8 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCC71830.1 - 4.2e-21 75.9 7.0 6.8e-21 75.2 2.9 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 CCC71830.1 - 4.7e-21 74.9 17.1 9.6e-21 73.9 5.1 2.9 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 CCC71830.1 - 1.6e-09 37.5 0.0 5.1e-06 26.3 0.0 3.0 3 0 0 3 3 3 2 UBA/TS-N domain zf-UBP_var PF17807.1 CCC71830.1 - 2.7e-08 33.4 4.8 2.7e-08 33.4 4.8 3.1 2 1 0 2 2 2 1 Variant UBP zinc finger zf-BED PF02892.15 CCC71830.1 - 0.46 10.5 7.8 0.54 10.3 1.5 3.5 3 0 0 3 3 3 0 BED zinc finger Wtap PF17098.5 CCC71831.1 - 0.00029 20.8 6.4 0.0007 19.6 6.4 1.7 1 1 0 1 1 1 1 WTAP/Mum2p family DUF4407 PF14362.6 CCC71831.1 - 0.0047 16.3 0.6 0.0047 16.3 0.6 1.6 1 1 0 2 2 2 1 Domain of unknown function (DUF4407) JAKMIP_CC3 PF16034.5 CCC71831.1 - 0.017 15.1 3.1 0.017 15.1 3.1 2.4 2 0 0 2 2 2 0 JAKMIP CC3 domain Sec2p PF06428.11 CCC71831.1 - 0.03 14.3 1.4 0.03 14.3 1.4 2.6 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p SOGA PF11365.8 CCC71831.1 - 0.052 14.7 12.3 0.57 11.3 0.8 3.2 2 1 0 2 2 2 0 Protein SOGA DivIC PF04977.15 CCC71831.1 - 0.053 13.3 6.8 2.5 7.9 1.4 3.4 3 0 0 3 3 3 0 Septum formation initiator FapA PF03961.13 CCC71831.1 - 0.093 11.3 7.8 1.8 7.1 4.7 2.1 1 1 1 2 2 2 0 Flagellar Assembly Protein A Csm1_N PF18504.1 CCC71831.1 - 4.2 7.8 13.6 0.41 11.0 1.9 3.3 3 1 0 3 3 3 0 Csm1 N-terminal domain WD40_alt PF14077.6 CCC71831.1 - 4.6 7.2 6.1 0.56 10.1 1.4 1.9 2 0 0 2 2 2 0 Alternative WD40 repeat motif HALZ PF02183.18 CCC71831.1 - 5.3 7.3 17.9 2.5 8.4 0.9 4.3 4 0 0 4 4 4 0 Homeobox associated leucine zipper CYSTM PF12734.7 CCC71832.1 - 1.1 9.7 56.0 1.8e+04 -9.5 56.0 3.4 1 1 0 1 1 1 0 Cysteine-rich TM module stress tolerance PXPV PF12778.7 CCC71832.1 - 9.2 6.2 13.1 27 4.7 13.1 1.7 1 1 0 1 1 1 0 PXPV repeat (3 copies) Cellulase PF00150.18 CCC71833.1 - 1.1e-11 44.7 4.7 1.1e-11 44.7 4.7 2.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Bac_rhodopsin PF01036.18 CCC71834.1 - 1.3e-43 149.2 17.4 1.6e-43 148.9 17.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF1772 PF08592.11 CCC71834.1 - 2.3 8.5 13.6 1.3 9.3 1.1 2.9 2 2 0 2 2 2 0 Domain of unknown function (DUF1772) DUF3309 PF11752.8 CCC71834.1 - 6.4 6.9 12.1 0.23 11.5 0.6 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3309) SGL PF08450.12 CCC71835.1 - 3.2e-54 184.1 0.4 3.8e-54 183.9 0.4 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 CCC71835.1 - 2.7e-06 27.5 0.1 0.028 14.6 0.0 4.0 4 0 0 4 4 4 2 Arylesterase DUF1752 PF08550.10 CCC71836.1 - 0.0079 16.0 1.5 0.0079 16.0 1.5 2.5 2 1 0 2 2 2 1 Fungal protein of unknown function (DUF1752) DUF4809 PF16067.5 CCC71836.1 - 0.025 14.7 0.6 0.072 13.3 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4809) DUF5428 PF17493.2 CCC71836.1 - 0.26 11.7 0.0 0.26 11.7 0.0 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5428) Myb_DNA-binding PF00249.31 CCC71837.1 - 1e-19 70.5 31.1 1.1e-13 51.1 0.8 6.5 7 1 0 7 7 7 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCC71837.1 - 2.7e-16 59.5 22.4 5.7e-14 52.1 2.8 5.4 4 1 0 4 4 4 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 CCC71837.1 - 0.04 14.1 0.8 0.36 11.0 0.1 2.8 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 MAR_sialic_bdg PF10564.9 CCC71837.1 - 0.17 12.0 3.4 3 7.9 0.2 2.9 2 0 0 2 2 2 0 Sialic-acid binding micronemal adhesive repeat Myb_DNA-bind_4 PF13837.6 CCC71837.1 - 0.68 10.4 0.1 0.68 10.4 0.1 4.8 5 1 0 5 5 5 0 Myb/SANT-like DNA-binding domain DUF1376 PF07120.11 CCC71837.1 - 2.1 8.7 5.6 1.8 9.0 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1376) Ribosomal_S17_N PF16205.5 CCC71838.1 - 1.7e-31 108.4 0.7 3e-31 107.6 0.7 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 CCC71838.1 - 3.4e-27 94.3 4.5 3.4e-27 94.3 4.5 1.6 2 0 0 2 2 2 1 Ribosomal protein S17 DUF922 PF06037.11 CCC71838.1 - 0.086 12.6 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF922) FMP23 PF17315.2 CCC71839.1 - 1.7e-55 187.3 0.3 2.2e-55 187.0 0.3 1.1 1 0 0 1 1 1 1 Found in mitochondrial proteome ADH_N PF08240.12 CCC71840.1 - 1.8e-29 101.8 1.7 2.3e-29 101.5 0.3 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCC71840.1 - 1.9e-24 86.1 0.9 2.8e-24 85.6 0.9 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCC71840.1 - 3e-06 28.3 0.1 4.6e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.20 CCC71840.1 - 0.13 12.4 1.5 0.42 10.7 1.5 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.26 CCC71841.1 - 1.1e-23 83.6 0.0 1.7e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCC71841.1 - 1.3e-16 61.9 0.0 2.7e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCC71841.1 - 1.1e-08 34.9 0.0 2.8e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain KR PF08659.10 CCC71841.1 - 0.04 13.8 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 KR domain ATG2_CAD PF13329.6 CCC71842.1 - 0.052 13.3 1.8 0.52 10.0 0.7 2.3 2 0 0 2 2 2 0 Autophagy-related protein 2 CAD motif Acyltransferase PF01553.21 CCC71844.1 - 2.5e-30 104.8 0.0 3.6e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 CCC71844.1 - 3.5e-13 49.4 0.5 6.3e-13 48.6 0.5 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus AMP-binding PF00501.28 CCC71845.1 - 1.4e-54 185.4 0.0 1.9e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 CCC71845.1 - 0.0073 17.3 0.0 0.014 16.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Renin_r PF07850.14 CCC71845.1 - 0.037 14.6 0.0 0.14 12.7 0.0 1.9 2 0 0 2 2 2 0 Renin receptor-like protein Fig1 PF12351.8 CCC71846.1 - 9.7e-57 191.9 4.4 9.7e-57 191.9 4.4 1.6 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.12 CCC71846.1 - 0.00026 20.7 14.0 0.00037 20.2 14.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family TraG_N PF07916.11 CCC71846.1 - 0.042 12.7 0.1 0.042 12.7 0.1 2.2 2 0 0 2 2 2 0 TraG-like protein, N-terminal region CCSMST1 PF15013.6 CCC71846.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.0 5 0 0 5 5 5 0 CCSMST1 family Sigma_reg_N PF13800.6 CCC71846.1 - 0.59 10.5 0.0 0.59 10.5 0.0 3.6 3 1 0 3 3 3 0 Sigma factor regulator N-terminal Endomucin PF07010.12 CCC71846.1 - 1.5 8.7 9.6 0.32 10.9 0.7 2.3 2 0 0 2 2 2 0 Endomucin DUF2700 PF10912.8 CCC71846.1 - 4.9 7.2 16.2 8.5 6.4 0.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2700) Orf78 PF06024.12 CCC71846.1 - 8.3 6.8 7.4 1 9.7 0.5 2.7 3 0 0 3 3 3 0 Orf78 (ac78) ATP-synt PF00231.19 CCC71847.1 - 2.7e-74 250.4 2.1 3e-74 250.2 2.1 1.0 1 0 0 1 1 1 1 ATP synthase DUF2100 PF09873.9 CCC71847.1 - 0.0081 16.0 1.0 0.016 15.1 1.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2100) Methyltransf_25 PF13649.6 CCC71848.1 - 4e-13 49.9 0.1 4.7e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 CCC71848.1 - 3.7e-12 46.2 0.0 6.5e-12 45.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 CCC71848.1 - 4.3e-10 39.6 0.0 1.1e-09 38.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC71848.1 - 1e-09 38.9 0.0 1e-08 35.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 CCC71848.1 - 1.5e-07 31.4 0.0 2.9e-07 30.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 CCC71848.1 - 1e-05 24.6 0.1 1.3e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 CCC71848.1 - 1e-05 25.0 0.0 1.5e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 CCC71848.1 - 1.7e-05 24.4 0.1 3.2e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 CCC71848.1 - 2.9e-05 24.0 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 CCC71848.1 - 0.00033 20.4 0.1 0.00054 19.7 0.1 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_2 PF00891.18 CCC71848.1 - 0.00075 18.9 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_12 PF08242.12 CCC71848.1 - 0.0013 19.5 0.0 0.003 18.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 CCC71848.1 - 0.0046 17.1 0.0 0.011 15.9 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Met_10 PF02475.16 CCC71848.1 - 0.0082 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_32 PF13679.6 CCC71848.1 - 0.011 15.8 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 CCC71848.1 - 0.025 13.9 0.2 0.046 13.0 0.2 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.19 CCC71848.1 - 0.029 14.1 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 CCC71848.1 - 0.076 12.7 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 DOT1 PF08123.13 CCC71848.1 - 0.087 12.3 0.1 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 PNP_phzG_C PF10590.9 CCC71849.1 - 2.3e-21 75.6 2.7 5.6e-21 74.4 2.7 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Putative_PNPOx PF01243.20 CCC71849.1 - 3.8e-12 46.2 0.0 5.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.7 CCC71849.1 - 0.064 13.9 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase zf-C2H2 PF00096.26 CCC71850.1 - 0.00098 19.4 8.7 0.5 10.9 0.2 3.5 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC71850.1 - 0.026 15.4 7.1 2.5 9.2 0.3 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger RNA_pol_Rbc25 PF08292.12 CCC71850.1 - 0.051 13.8 0.0 0.2 11.9 0.0 2.1 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 zf-C2H2_6 PF13912.6 CCC71850.1 - 0.059 13.4 4.3 1.7 8.7 0.0 3.0 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCC71850.1 - 0.26 11.8 0.1 0.26 11.8 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain Oxysterol_BP PF01237.18 CCC71851.1 - 3e-133 444.3 0.1 5.8e-133 443.3 0.1 1.5 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 CCC71851.1 - 1.8e-11 44.4 0.4 1.8e-11 44.4 0.4 3.1 3 0 0 3 3 3 1 PH domain PH_8 PF15409.6 CCC71851.1 - 1.8e-10 40.9 2.6 2.2e-10 40.6 0.6 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_2 PF12796.7 CCC71851.1 - 3.5e-10 40.3 1.3 3.1e-05 24.5 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 CCC71851.1 - 3.6e-10 39.9 4.0 5.8e-05 23.3 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 CCC71851.1 - 1.4e-09 38.3 0.3 0.00012 22.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 CCC71851.1 - 5.5e-09 35.6 1.4 0.033 14.7 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 CCC71851.1 - 1.3e-07 31.8 0.9 0.0037 17.6 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat PH_11 PF15413.6 CCC71851.1 - 0.13 12.7 6.6 0.47 10.9 3.1 3.3 2 1 0 2 2 2 0 Pleckstrin homology domain V_ATPase_I PF01496.19 CCC71851.1 - 0.16 9.9 5.5 0.27 9.1 5.5 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3362 PF11842.8 CCC71851.1 - 0.21 11.9 1.6 0.64 10.3 1.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3362) DUF5423 PF17461.2 CCC71851.1 - 0.4 9.5 11.4 0.0091 14.9 2.7 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5423) Carn_acyltransf PF00755.20 CCC71852.1 - 5.6e-205 682.4 0.2 7.1e-205 682.1 0.2 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1892 PF08987.10 CCC71852.1 - 0.12 12.6 0.4 0.86 9.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1892) SAICAR_synt PF01259.18 CCC71853.1 - 1.3e-100 336.2 0.1 1.5e-100 336.0 0.1 1.0 1 0 0 1 1 1 1 SAICAR synthetase EMP24_GP25L PF01105.24 CCC71854.1 - 4.6e-32 111.4 2.2 5.8e-32 111.1 2.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Astacin PF01400.24 CCC71854.1 - 0.033 13.8 2.6 0.044 13.4 2.6 1.2 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Pkinase PF00069.25 CCC71855.1 - 5.2e-39 134.2 0.0 1.1e-22 80.7 0.0 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71855.1 - 1.1e-13 51.1 0.0 2.6e-09 36.7 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.23 CCC71855.1 - 0.007 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4452 PF14618.6 CCC71855.1 - 0.017 15.0 0.1 0.031 14.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) Pkinase_fungal PF17667.1 CCC71855.1 - 0.019 13.7 0.0 0.035 12.9 0.0 1.4 1 1 0 1 1 1 0 Fungal protein kinase Kinase-like PF14531.6 CCC71855.1 - 0.12 11.7 0.0 11 5.2 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Steroid_dh PF02544.16 CCC71856.1 - 1.4e-34 119.3 10.1 2.4e-34 118.5 10.1 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Fibrillarin PF01269.17 CCC71857.1 - 4.1e-108 359.7 0.0 4.9e-108 359.5 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 CCC71857.1 - 1.3e-05 25.0 0.1 2.3e-05 24.2 0.1 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 CCC71857.1 - 0.012 15.8 0.0 0.015 15.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.19 CCC71857.1 - 0.083 12.6 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 CCC71857.1 - 0.1 12.2 0.0 0.23 11.1 0.0 1.5 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F CYSTM PF12734.7 CCC71858.1 - 4.8e-14 52.4 10.1 4.8e-14 52.4 10.1 4.7 1 1 1 2 2 2 1 Cysteine-rich TM module stress tolerance Velvet PF11754.8 CCC71858.1 - 0.0063 16.5 4.0 0.0071 16.3 4.0 1.0 1 0 0 1 1 1 1 Velvet factor DUF2076 PF09849.9 CCC71858.1 - 1.7 8.6 21.9 2.1 8.3 21.9 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) zf-RING_UBOX PF13445.6 CCC71859.1 - 0.0017 18.3 0.0 0.0057 16.7 0.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 CCC71859.1 - 0.0031 17.3 0.2 0.0086 15.9 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 CCC71859.1 - 0.0033 17.3 0.1 0.0092 15.8 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCC71859.1 - 0.0069 16.3 2.7 0.016 15.2 2.7 1.7 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCC71859.1 - 0.012 15.5 0.1 0.033 14.0 0.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 IBR PF01485.21 CCC71859.1 - 0.071 13.3 1.5 0.52 10.6 0.4 2.5 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 CCC71859.1 - 0.086 13.2 0.1 0.27 11.6 0.1 1.8 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_3 PF13920.6 CCC71859.1 - 0.092 12.6 0.2 0.25 11.2 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Fer2_3 PF13085.6 CCC71859.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-C3HC4_4 PF15227.6 CCC71859.1 - 0.17 12.0 1.8 0.2 11.8 0.2 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 CCC71859.1 - 0.18 11.6 0.3 0.43 10.4 0.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 CCC71860.1 - 7.8e-34 115.6 4.3 9.7e-34 115.3 4.3 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 CCC71860.1 - 1.4e-18 66.9 10.9 2.2e-18 66.3 10.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 CCC71860.1 - 9e-06 25.9 14.4 0.00012 22.3 14.4 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 CCC71860.1 - 0.0061 16.5 12.5 0.14 12.1 13.0 2.4 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 CCC71860.1 - 0.013 15.3 10.6 0.064 13.1 10.6 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCC71860.1 - 0.016 15.1 12.7 0.1 12.5 10.5 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 CCC71860.1 - 0.02 15.0 10.0 0.22 11.7 10.0 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.6 CCC71860.1 - 0.025 14.6 11.0 0.45 10.6 6.6 2.9 2 1 0 2 2 2 0 RING-type zinc-finger CENP-B_dimeris PF09026.10 CCC71860.1 - 0.051 14.0 4.3 0.072 13.5 4.3 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-RING_4 PF14570.6 CCC71860.1 - 0.074 12.9 1.2 0.074 12.9 1.2 3.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.14 CCC71860.1 - 0.17 11.7 0.4 2 8.3 0.0 2.4 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-HC5HC2H PF13771.6 CCC71860.1 - 0.22 11.8 10.9 0.12 12.6 6.8 2.3 1 1 1 2 2 2 0 PHD-like zinc-binding domain zf-C3HC4_3 PF13920.6 CCC71860.1 - 0.29 11.0 13.2 0.32 10.9 8.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CCC71860.1 - 0.72 9.5 13.9 5 6.8 10.0 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H_2 PF13832.6 CCC71860.1 - 0.9 9.7 9.2 0.3 11.3 6.4 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain Trm112p PF03966.16 CCC71860.1 - 1.3 9.6 5.0 23 5.6 0.0 2.7 2 1 0 2 2 2 0 Trm112p-like protein DiS_P_DiS PF06750.13 CCC71860.1 - 1.6 8.9 9.2 2.3 8.4 6.9 2.3 2 1 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain zf-RING-like PF08746.11 CCC71860.1 - 1.7 9.0 10.0 4.3 7.7 10.0 1.8 1 1 0 1 1 1 0 RING-like domain PHD PF00628.29 CCC71860.1 - 1.9 8.4 12.0 4.7 7.2 11.0 2.2 1 1 0 1 1 1 0 PHD-finger zf-RING_6 PF14835.6 CCC71860.1 - 3.4 7.6 7.7 2.6 8.0 5.7 1.8 1 1 1 2 2 2 0 zf-RING of BARD1-type protein Tcp11 PF05794.13 CCC71861.1 - 7.8e-136 453.7 2.8 7.8e-136 453.7 2.8 2.2 2 1 0 2 2 2 1 T-complex protein 11 DUF2946 PF11162.8 CCC71861.1 - 0.37 11.5 3.9 0.82 10.3 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Maf1 PF09174.10 CCC71862.1 - 4.2e-06 27.0 2.9 7e-06 26.3 2.9 1.4 1 1 0 1 1 1 1 Maf1 regulator ATG101 PF07855.12 CCC71862.1 - 0.039 13.9 0.1 0.049 13.6 0.1 1.1 1 0 0 1 1 1 0 Autophagy-related protein 101 CRAM_rpt PF07016.11 CCC71862.1 - 2.4 8.0 6.7 0.16 11.8 1.6 1.6 2 0 0 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor Rad51 PF08423.11 CCC71863.1 - 1.3e-47 162.2 0.4 1.1e-41 142.8 0.1 2.3 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.6 CCC71863.1 - 3e-06 27.0 0.0 5.3e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain RecA PF00154.21 CCC71863.1 - 5e-06 26.2 0.7 1e-05 25.2 0.7 1.4 1 1 0 1 1 1 1 recA bacterial DNA recombination protein ATPase PF06745.13 CCC71863.1 - 0.00014 21.3 1.4 0.00014 21.3 1.4 2.6 3 1 0 3 3 3 1 KaiC AAA_24 PF13479.6 CCC71863.1 - 0.0058 16.4 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RCR PF12273.8 CCC71864.1 - 1.4e-34 119.3 1.1 1.4e-34 119.3 1.1 2.0 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Pox_EPC_I2-L1 PF12575.8 CCC71864.1 - 0.17 12.1 0.1 0.27 11.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 SARAF PF06682.12 CCC71864.1 - 0.25 10.9 2.1 1.5 8.4 2.1 2.1 1 1 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis polyprenyl_synt PF00348.17 CCC71865.1 - 8.5e-70 234.7 0.0 3.7e-68 229.3 0.0 2.7 1 1 0 1 1 1 1 Polyprenyl synthetase Cofilin_ADF PF00241.20 CCC71866.1 - 2.3e-28 98.4 0.3 3.1e-14 52.8 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF1947 PF09183.10 CCC71866.1 - 0.16 12.3 2.5 0.65 10.3 0.5 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF1947) DUF3078 PF11276.8 CCC71867.1 - 0.094 13.2 2.7 0.91 10.0 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3078) PI3_PI4_kinase PF00454.27 CCC71868.1 - 6.2e-55 186.7 0.5 6.2e-55 186.7 0.5 2.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.13 CCC71868.1 - 2.8e-25 88.2 0.0 1.3e-24 86.0 0.0 2.3 1 0 0 1 1 1 1 UME (NUC010) domain FATC PF02260.20 CCC71868.1 - 3.1e-13 49.3 0.1 6e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 FATC domain FAT PF02259.23 CCC71868.1 - 8.2e-07 28.6 4.7 2e-06 27.3 4.7 1.7 1 0 0 1 1 1 1 FAT domain TPR_19 PF14559.6 CCC71868.1 - 0.011 16.3 0.0 0.027 15.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 CCC71868.1 - 0.15 13.0 0.1 0.73 10.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat CKS PF01111.19 CCC71869.1 - 5e-34 116.4 0.1 7.8e-34 115.8 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit SUIM_assoc PF16619.5 CCC71869.1 - 0.00054 20.0 1.3 0.00066 19.7 1.3 1.3 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Med3 PF11593.8 CCC71869.1 - 3.8 6.6 16.1 4.6 6.3 16.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PRMT5_TIM PF17285.2 CCC71870.1 - 8.4e-63 212.0 1.3 1.2e-62 211.4 1.3 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 CCC71870.1 - 1.4e-61 207.5 0.2 2.2e-61 206.8 0.2 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain PRMT5 PF05185.16 CCC71870.1 - 1.2e-59 201.1 0.0 2e-59 200.3 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.16 CCC71870.1 - 0.051 13.3 0.0 0.093 12.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein RhoGAP PF00620.27 CCC71871.1 - 8.3e-09 35.4 2.9 1.9e-08 34.3 0.1 2.5 2 1 0 2 2 2 1 RhoGAP domain FCH PF00611.23 CCC71871.1 - 3.9e-08 33.5 0.1 4.9e-07 29.9 0.0 2.6 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DEP PF00610.21 CCC71871.1 - 5.4e-08 32.8 0.1 1.3e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF2312 PF10073.9 CCC71871.1 - 0.02 14.5 1.4 0.039 13.6 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) CRC_subunit PF08624.10 CCC71872.1 - 5.8e-40 136.8 0.0 1.4e-39 135.6 0.0 1.7 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit PcfK PF14058.6 CCC71872.1 - 0.032 14.5 0.1 0.069 13.4 0.1 1.5 1 0 0 1 1 1 0 PcfK-like protein NAD_Gly3P_dh_N PF01210.23 CCC71873.1 - 2.9e-52 176.8 0.1 4.4e-52 176.2 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.14 CCC71873.1 - 2.6e-42 144.5 0.1 4.6e-42 143.7 0.1 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.17 CCC71873.1 - 0.099 13.2 0.0 12 6.5 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Pkinase PF00069.25 CCC71874.1 - 1.3e-50 172.2 0.1 5.4e-50 170.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71874.1 - 3e-24 85.7 0.0 6.8e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC71874.1 - 0.0037 16.6 0.0 0.0084 15.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CCC71874.1 - 0.016 14.8 0.2 1.4 8.4 0.0 2.9 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2249 PF10006.9 CCC71874.1 - 0.036 13.9 0.0 0.09 12.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Pkinase PF00069.25 CCC71876.1 - 1.8e-55 188.2 0.0 3.5e-55 187.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71876.1 - 5.9e-25 88.0 0.0 1.2e-24 87.0 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 CCC71876.1 - 0.00013 21.7 1.2 0.18 11.4 0.0 3.1 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 CCC71876.1 - 0.002 18.1 0.0 1.5 8.6 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 CCC71876.1 - 0.01 15.2 0.1 0.15 11.4 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 CCC71876.1 - 0.016 14.8 0.2 0.054 13.1 0.1 1.9 1 1 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 CCC71876.1 - 0.018 14.4 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Kinase-like tRNA-synt_2 PF00152.20 CCC71877.1 - 1.5e-63 214.8 0.1 2.4e-63 214.1 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 CCC71877.1 - 8.1e-08 32.1 0.0 1.6e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 CCC71877.1 - 2.5e-07 30.4 0.7 0.00016 21.3 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) RhoGAP-FF1 PF16512.5 CCC71877.1 - 0.036 14.7 0.6 0.12 13.1 0.1 2.1 2 0 0 2 2 2 0 p190-A and -B Rho GAPs FF domain DUF2963 PF11178.8 CCC71877.1 - 0.11 12.2 2.2 6.4 6.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) tRNA_Me_trans PF03054.16 CCC71878.1 - 1.1e-115 386.2 0.0 1.3e-115 386.0 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 CCC71878.1 - 0.00055 19.1 0.0 0.13 11.3 0.0 2.5 2 1 0 2 2 2 2 NAD synthase Asn_synthase PF00733.21 CCC71878.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Asparagine synthase Git3 PF11710.8 CCC71879.1 - 9.6e-77 257.3 11.5 1.7e-76 256.6 11.5 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 GPR_Gpa2_C PF11970.8 CCC71879.1 - 7.9e-30 102.7 3.2 7.9e-30 102.7 3.2 2.0 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Inv-AAD PF18785.1 CCC71880.1 - 3.7e-38 130.3 0.1 9.1e-38 129.0 0.1 1.7 2 0 0 2 2 2 1 Invertebrate-AID/APOBEC-deaminase PseudoU_synth_2 PF00849.22 CCC71880.1 - 4.4e-34 117.9 0.4 9.5e-34 116.8 0.0 1.7 2 0 0 2 2 2 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.23 CCC71880.1 - 9.6e-20 70.4 0.0 1.6e-19 69.6 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCC71880.1 - 1.7e-06 27.8 0.0 2.8e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase NARP1 PF12569.8 CCC71881.1 - 1.2e-109 367.6 26.2 8.3e-81 272.4 4.7 3.4 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 CCC71881.1 - 2.6e-11 42.7 8.0 0.018 15.1 0.0 7.2 9 0 0 9 9 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 CCC71881.1 - 1.3e-08 35.3 0.3 0.1 13.2 0.0 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 CCC71881.1 - 2.4e-07 30.4 22.1 0.0012 18.8 0.1 8.3 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.6 CCC71881.1 - 3.4e-07 30.5 4.6 1.8 9.6 0.0 6.9 7 1 1 8 8 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 CCC71881.1 - 1.5e-06 28.6 4.8 1.9 9.1 0.0 6.0 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 CCC71881.1 - 2.6e-06 27.0 6.2 0.35 10.8 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 CCC71881.1 - 7.4e-05 22.9 8.9 0.87 10.1 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 CCC71881.1 - 0.00036 20.2 2.2 0.082 12.6 0.0 3.8 4 0 0 4 4 4 1 TPR repeat ANAPC3 PF12895.7 CCC71881.1 - 0.0027 17.9 11.5 0.14 12.4 0.8 4.5 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 CCC71881.1 - 0.0037 17.5 6.6 1.2 9.4 0.0 5.7 5 3 0 5 5 4 1 Tetratricopeptide repeat NPAT_C PF15712.5 CCC71881.1 - 0.0093 14.7 2.5 0.013 14.2 2.5 1.1 1 0 0 1 1 1 1 NPAT C terminus Fis1_TPR_C PF14853.6 CCC71881.1 - 0.022 14.9 5.3 0.093 12.8 0.1 3.6 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 CCC71881.1 - 0.2 12.1 1.9 4.9 7.6 0.1 3.2 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation Sel1 PF08238.12 CCC71881.1 - 1.1 10.1 3.0 1.3 9.8 0.0 2.9 4 0 0 4 4 2 0 Sel1 repeat HLH PF00010.26 CCC71882.1 - 1.2e-16 60.4 0.0 6.2e-16 58.1 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ZapB PF06005.12 CCC71882.1 - 0.029 14.8 0.7 0.39 11.2 0.4 2.2 2 1 0 2 2 2 0 Cell division protein ZapB DUF592 PF04574.13 CCC71883.1 - 2.2e-65 219.1 1.7 4.5e-65 218.1 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) SIR2 PF02146.17 CCC71883.1 - 2.3e-65 219.8 0.0 3.6e-65 219.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 CCC71883.1 - 0.00072 19.3 0.0 0.5 10.1 0.0 2.7 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Aldo_ket_red PF00248.21 CCC71884.1 - 1.2e-61 208.5 0.0 1.3e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.12 CCC71884.1 - 0.0082 15.7 0.1 0.019 14.6 0.0 1.6 2 0 0 2 2 2 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) SF3A2 PF16835.5 CCC71885.1 - 1.3e-23 83.2 0.1 2.4e-23 82.3 0.1 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 CCC71885.1 - 9.2e-07 29.1 1.3 1.8e-06 28.1 1.3 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 CCC71885.1 - 0.012 15.4 0.1 0.021 14.6 0.1 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_2 PF12756.7 CCC71885.1 - 0.031 14.6 0.2 0.06 13.7 0.2 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) YkuI_C PF10388.9 CCC71886.1 - 0.4 10.5 6.4 0.87 9.4 0.2 3.1 2 1 1 3 3 3 0 EAL-domain associated signalling protein domain PAPS_reduct PF01507.19 CCC71887.1 - 2e-35 122.4 0.0 2.6e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family CHCH PF06747.13 CCC71888.1 - 9.6e-06 25.6 0.4 1.3e-05 25.2 0.4 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 CCC71888.1 - 0.00038 20.4 1.5 0.00043 20.2 1.5 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CX9C PF16860.5 CCC71888.1 - 0.03 14.3 2.0 0.048 13.7 2.0 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, E1_DerP2_DerF2 PF02221.15 CCC71889.1 - 4.1e-27 95.2 0.0 4.8e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 ML domain Metallophos PF00149.28 CCC71890.1 - 1.5e-38 133.3 0.1 2e-38 133.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 CCC71890.1 - 0.00055 20.3 0.1 0.0012 19.3 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_hydro_65N PF03636.15 CCC71890.1 - 0.09 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Mitoc_mL59 PF18126.1 CCC71891.1 - 0.028 14.7 1.2 0.028 14.7 1.2 1.5 1 1 0 1 1 1 0 Mitochondrial ribosomal protein mL59 Prefoldin PF02996.17 CCC71892.1 - 7.2e-36 122.7 0.8 1e-35 122.3 0.8 1.2 1 0 0 1 1 1 1 Prefoldin subunit Pox_A_type_inc PF04508.12 CCC71892.1 - 0.00014 21.5 0.2 0.064 13.1 0.0 2.7 2 0 0 2 2 2 2 Viral A-type inclusion protein repeat Prefoldin_2 PF01920.20 CCC71892.1 - 0.0012 18.8 3.1 0.0045 16.9 0.5 2.3 1 1 1 2 2 2 1 Prefoldin subunit SNAD4 PF18750.1 CCC71892.1 - 0.0045 17.1 0.2 0.058 13.5 0.1 2.1 2 0 0 2 2 2 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC_C PF05240.14 CCC71892.1 - 0.027 14.4 0.2 4 7.5 0.0 2.4 2 0 0 2 2 2 0 APOBEC-like C-terminal domain DUF1664 PF07889.12 CCC71892.1 - 0.054 13.5 0.2 2.3 8.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) APOBEC2 PF18772.1 CCC71892.1 - 0.056 13.5 1.0 3.6 7.6 0.0 2.2 2 0 0 2 2 2 0 APOBEC2 PET PF06297.14 CCC71892.1 - 0.097 13.0 0.1 0.2 12.0 0.1 1.5 1 0 0 1 1 1 0 PET Domain CENP-F_leu_zip PF10473.9 CCC71892.1 - 0.12 12.4 6.2 0.44 10.6 2.2 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SUN PF03856.13 CCC71893.1 - 2.7e-80 269.4 17.4 3.3e-80 269.1 17.4 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Haem_degrading PF03928.14 CCC71894.1 - 4.2e-28 97.8 0.0 5e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Haem-degrading DprA_WH PF17782.1 CCC71894.1 - 2.3 8.4 4.3 0.81 9.9 0.3 2.0 2 0 0 2 2 2 0 DprA winged helix domain NatB_MDM20 PF09797.9 CCC71896.1 - 2.2e-47 161.8 12.8 8.1e-47 160.0 10.6 2.7 2 1 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit YopX PF09643.10 CCC71896.1 - 0.1 12.7 0.8 0.35 10.9 0.1 2.3 2 0 0 2 2 2 0 YopX protein Peptidase_S10 PF00450.22 CCC71897.1 - 4.3e-127 425.0 0.4 5.1e-127 424.8 0.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase RasGAP PF00616.19 CCC71898.1 - 8.2e-21 74.7 0.3 5e-14 52.5 0.1 3.0 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase Velvet PF11754.8 CCC71898.1 - 0.011 15.6 1.0 0.03 14.3 0.4 2.0 2 0 0 2 2 2 0 Velvet factor SR-25 PF10500.9 CCC71898.1 - 3.1 7.4 6.4 6.5 6.3 6.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Bmt2 PF11968.8 CCC71899.1 - 2.7e-81 272.6 0.3 4.4e-81 271.9 0.3 1.3 1 0 0 1 1 1 1 25S rRNA (adenine(2142)-N(1))-methyltransferase, Bmt2 Methyltransf_8 PF05148.15 CCC71899.1 - 0.0046 16.8 0.0 0.0077 16.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.6 CCC71899.1 - 0.0065 16.3 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 CCC71899.1 - 0.019 15.6 0.0 0.038 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF1514 PF07438.11 CCC71899.1 - 0.075 12.9 0.4 0.27 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) Methyltransf_12 PF08242.12 CCC71899.1 - 0.078 13.7 0.0 0.24 12.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.29 CCC71900.1 - 2.2e-40 138.3 0.1 4.2e-40 137.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC71900.1 - 2.6e-31 108.2 3.3 3.9e-27 94.8 0.1 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 CCC71900.1 - 2.9e-07 30.6 0.3 2.9e-07 30.6 0.3 2.2 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit UCR_UQCRX_QCR9 PF05365.12 CCC71900.1 - 0.056 13.4 0.3 0.15 12.1 0.3 1.7 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like eRF1_2 PF03464.15 CCC71901.1 - 5.2e-46 156.3 0.1 8.7e-46 155.5 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 CCC71901.1 - 9.4e-37 126.0 0.5 2e-36 124.9 0.5 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 CCC71901.1 - 2.2e-20 72.9 0.0 4.8e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 CCC71901.1 - 9.6e-11 42.1 0.0 1.5e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 CCC71901.1 - 8.7e-09 35.8 0.1 1.3e-08 35.2 0.1 1.2 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 ATG19_autophagy PF12744.7 CCC71902.1 - 0.0026 17.0 0.1 0.0059 15.8 0.0 1.6 2 0 0 2 2 2 1 Autophagy protein Atg19, Atg8-binding DUF1877 PF08974.10 CCC71902.1 - 0.0062 16.7 0.1 0.0083 16.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1877) PDZ_4 PF17816.1 CCC71902.1 - 0.076 13.4 0.8 0.21 12.0 0.4 1.8 1 1 1 2 2 2 0 PDZ domain TLV_coat PF00429.19 CCC71902.1 - 0.14 10.8 1.0 0.24 10.0 1.0 1.3 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) ADH_N PF08240.12 CCC71903.1 - 2.5e-30 104.6 0.3 6e-30 103.3 0.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 CCC71903.1 - 2.1e-28 98.9 2.0 3.3e-28 98.3 2.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 CCC71903.1 - 4e-06 27.9 0.1 6.7e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.20 CCC71903.1 - 0.0039 17.3 1.5 0.0076 16.4 1.5 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Glu_dehyd_C PF16912.5 CCC71903.1 - 0.0056 16.2 0.3 0.0077 15.7 0.3 1.1 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ELFV_dehydrog PF00208.21 CCC71903.1 - 0.021 14.5 0.3 0.029 14.1 0.3 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase YbjQ_1 PF01906.17 CCC71903.1 - 0.026 15.2 1.0 0.07 13.8 0.2 2.2 2 0 0 2 2 2 0 Putative heavy-metal-binding NqrM PF04400.13 CCC71903.1 - 0.1 12.4 1.6 0.2 11.4 0.5 2.0 2 0 0 2 2 2 0 (Na+)-NQR maturation NqrM Ribosomal_S9 PF00380.19 CCC71904.1 - 7.4e-40 136.2 0.1 1.2e-39 135.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Myofilin PF15929.5 CCC71904.1 - 0.098 13.0 0.0 0.27 11.6 0.0 1.7 1 0 0 1 1 1 0 Myofilin RNA_pol_Rpb5_C PF01191.19 CCC71905.1 - 3.8e-32 110.0 0.3 7.3e-32 109.1 0.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 CCC71905.1 - 1.3e-28 99.4 0.2 2.4e-28 98.5 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Sof1 PF04158.14 CCC71905.1 - 0.025 14.9 0.4 0.048 13.9 0.4 1.4 1 0 0 1 1 1 0 Sof1-like domain Mrr_cat PF04471.12 CCC71905.1 - 0.072 13.1 0.0 0.19 11.8 0.0 1.7 2 0 0 2 2 2 0 Restriction endonuclease SH3_2 PF07653.17 CCC71905.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 Variant SH3 domain RibD_C PF01872.17 CCC71906.1 - 2.2e-36 125.6 0.0 2.5e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain LpoB PF13036.6 CCC71906.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Peptidoglycan-synthase activator LpoB MFAP1 PF06991.11 CCC71907.1 - 5.5e-07 29.6 15.4 5.5e-07 29.6 15.4 2.1 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing REPA_OB_2 PF16900.5 CCC71907.1 - 0.014 15.3 0.1 0.22 11.5 0.1 2.5 2 0 0 2 2 2 0 Replication protein A OB domain Suc_Fer-like PF06999.12 CCC71908.1 - 7.5e-49 166.3 0.0 1.1e-48 165.7 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Fungal_trans PF04082.18 CCC71909.1 - 2.1e-11 43.4 6.1 5e-11 42.1 6.1 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.18 CCC71909.1 - 2.7e-08 33.8 8.3 5.1e-08 32.9 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RNase_H2_suC PF08615.11 CCC71909.1 - 0.054 13.7 0.0 0.24 11.6 0.0 2.1 1 1 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Aldo_ket_red PF00248.21 CCC71910.1 - 5.1e-40 137.5 0.0 1.4e-38 132.8 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family GYF_2 PF14237.6 CCC71910.1 - 0.14 12.0 0.1 0.78 9.6 0.0 2.4 3 0 0 3 3 3 0 GYF domain 2 DivIC PF04977.15 CCC71911.1 - 3.8 7.4 8.9 4.9 7.0 0.5 3.4 2 1 0 2 2 2 0 Septum formation initiator DUF3450 PF11932.8 CCC71911.1 - 4.4 6.5 11.3 4.1 6.7 1.7 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3450) PQ-loop PF04193.14 CCC71912.1 - 1.7e-38 130.2 18.8 9.6e-21 73.3 3.1 3.1 3 0 0 3 3 3 2 PQ loop repeat Vps52 PF04129.12 CCC71913.1 - 1.2e-139 466.3 28.8 1.7e-139 465.9 28.8 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family YL1 PF05764.13 CCC71914.1 - 7.9e-46 157.2 62.3 7.9e-46 157.2 62.3 2.9 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 CCC71914.1 - 3.2e-12 46.0 0.2 5.4e-12 45.3 0.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain DUF4986 PF16375.5 CCC71914.1 - 0.11 13.2 0.8 1 10.1 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function Snf7 PF03357.21 CCC71915.1 - 4.1e-37 127.4 20.1 5.5e-37 127.0 20.1 1.1 1 0 0 1 1 1 1 Snf7 Fmp27_WPPW PF10359.9 CCC71915.1 - 0.00039 19.4 14.2 0.00048 19.1 10.3 1.9 1 1 1 2 2 2 1 RNA pol II promoter Fmp27 protein domain CLZ PF16526.5 CCC71915.1 - 0.0034 17.7 1.5 0.0034 17.7 1.5 3.2 3 1 1 4 4 3 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF5082 PF16888.5 CCC71915.1 - 0.0082 16.4 3.6 0.0082 16.4 3.6 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF5082) Serine_rich PF08824.10 CCC71915.1 - 0.064 13.3 13.2 0.031 14.3 8.4 2.3 1 1 1 2 2 2 0 Serine rich protein interaction domain BLOC1_2 PF10046.9 CCC71915.1 - 0.22 11.9 15.8 0.98 9.8 1.6 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 CCC71915.1 - 0.25 11.4 12.9 0.76 9.8 3.5 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) YlqD PF11068.8 CCC71915.1 - 0.29 11.5 20.0 3.8 7.9 20.0 2.3 1 1 0 1 1 1 0 YlqD protein Exonuc_VII_L PF02601.15 CCC71915.1 - 0.57 9.7 13.2 0.77 9.3 13.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Cep57_MT_bd PF06657.13 CCC71915.1 - 0.69 10.4 10.6 0.15 12.6 1.8 3.0 2 2 2 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Tweety PF04906.13 CCC71915.1 - 0.83 8.3 10.6 2.9 6.4 1.3 2.0 1 1 1 2 2 2 0 Tweety Not3 PF04065.15 CCC71915.1 - 0.96 8.8 12.8 1.3 8.4 11.8 1.7 1 1 1 2 2 2 0 Not1 N-terminal domain, CCR4-Not complex component SKA1 PF07160.12 CCC71915.1 - 1 9.2 14.4 4.3 7.1 14.4 1.9 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 FlaC_arch PF05377.11 CCC71915.1 - 1.1 9.7 6.3 4.1 7.9 0.1 3.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) PUFD PF16553.5 CCC71915.1 - 1.4 9.0 5.9 0.63 10.2 0.5 2.2 1 1 1 2 2 2 0 BCORL-PCGF1-binding domain Jnk-SapK_ap_N PF09744.9 CCC71915.1 - 2.2 8.5 17.0 0.6 10.3 8.5 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 LMBR1 PF04791.16 CCC71915.1 - 2.8 6.8 6.2 3.5 6.4 6.2 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Fib_alpha PF08702.10 CCC71915.1 - 3 8.0 17.6 2.8 8.1 4.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family FliJ PF02050.16 CCC71915.1 - 3.8 7.8 19.4 0.19 11.9 10.6 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein FapA PF03961.13 CCC71915.1 - 8.9 4.8 10.0 12 4.3 8.3 1.8 1 1 1 2 2 2 0 Flagellar Assembly Protein A DHBP_synthase PF00926.19 CCC71916.1 - 1.4e-83 279.2 0.1 1.6e-83 279.0 0.1 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase WD40 PF00400.32 CCC71917.1 - 0.00073 20.3 1.3 0.003 18.4 1.0 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC71917.1 - 0.019 15.2 0.0 0.056 13.7 0.0 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain SLD5_C PF16922.5 CCC71918.1 - 2.4e-22 78.9 0.1 4.7e-22 77.9 0.1 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 CCC71918.1 - 6.1e-11 42.8 0.3 1.2e-09 38.6 0.3 2.2 2 0 0 2 2 2 1 GINS complex protein FBA_2 PF07735.17 CCC71918.1 - 0.1 12.8 0.3 11 6.3 0.1 3.3 4 0 0 4 4 4 0 F-box associated CPL PF08144.11 CCC71919.1 - 2.6e-52 177.0 5.5 3.7e-49 166.7 0.1 4.6 4 1 0 4 4 4 2 CPL (NUC119) domain PUF PF00806.19 CCC71919.1 - 3.5e-05 23.2 4.3 0.76 9.6 0.0 5.1 6 0 0 6 6 6 2 Pumilio-family RNA binding repeat SAC3 PF12209.8 CCC71919.1 - 0.13 12.5 7.5 0.82 9.9 0.0 4.8 4 1 1 5 5 5 0 Leucine permease transcriptional regulator helical domain DUF1387 PF07139.11 CCC71919.1 - 1.1 8.9 13.4 2.3 7.9 13.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Sugar_tr PF00083.24 CCC71920.1 - 1.2e-135 453.0 29.7 1.4e-135 452.7 29.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC71920.1 - 9.3e-32 110.3 36.0 5.6e-31 107.7 29.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCC71920.1 - 3.2e-07 29.2 2.1 3.2e-07 29.2 2.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 CCC71920.1 - 0.0016 17.0 0.3 0.0016 17.0 0.3 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector DUF1279 PF06916.13 CCC71920.1 - 0.036 14.6 0.4 0.2 12.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) VQ PF05678.14 CCC71920.1 - 0.14 11.7 0.1 0.57 9.7 0.0 2.0 2 0 0 2 2 2 0 VQ motif DUF2530 PF10745.9 CCC71920.1 - 8.1 6.8 7.1 4.6 7.5 0.2 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2530) Sec20 PF03908.13 CCC71921.1 - 3e-27 94.4 0.5 3e-27 94.4 0.5 2.2 3 0 0 3 3 3 1 Sec20 Vps39_2 PF10367.9 CCC71922.1 - 0.18 12.3 5.3 0.65 10.5 0.3 3.5 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 HlyIII PF03006.20 CCC71925.1 - 5.6e-51 173.4 27.9 6.6e-51 173.2 27.9 1.0 1 0 0 1 1 1 1 Haemolysin-III related ERG4_ERG24 PF01222.17 CCC71926.1 - 5e-165 549.5 16.0 5.6e-165 549.3 16.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 CCC71926.1 - 2.2e-06 27.4 1.4 2.2e-06 27.4 1.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Aha1_N PF09229.11 CCC71929.1 - 1.8e-28 99.5 1.6 2.1e-28 99.2 1.6 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal RNase_P_pop3 PF08228.11 CCC71930.1 - 4.6e-42 143.7 2.8 5.7e-42 143.5 2.8 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 WSC PF01822.19 CCC71931.1 - 1.3e-12 47.7 16.4 1.3e-12 47.7 16.4 2.9 3 1 0 3 3 3 1 WSC domain CYYR1 PF10873.8 CCC71931.1 - 0.0025 18.3 0.0 0.0025 18.3 0.0 2.0 2 0 0 2 2 2 1 Cysteine and tyrosine-rich protein 1 Syndecan PF01034.20 CCC71931.1 - 0.0025 17.7 0.2 0.0053 16.6 0.2 1.5 1 0 0 1 1 1 1 Syndecan domain DUF4448 PF14610.6 CCC71931.1 - 0.027 14.2 5.5 0.091 12.5 5.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) EphA2_TM PF14575.6 CCC71931.1 - 0.048 14.5 1.0 0.16 12.9 0.0 2.4 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 CCC71931.1 - 0.21 11.9 0.1 0.21 11.9 0.1 3.3 2 1 0 3 3 3 0 Orf78 (ac78) RIFIN PF02009.16 CCC71931.1 - 0.45 10.4 15.4 1.4 8.7 15.3 1.8 1 1 1 2 2 2 0 Rifin SKG6 PF08693.10 CCC71931.1 - 0.65 9.5 12.9 0.024 14.1 4.1 3.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Insulin_TMD PF17870.1 CCC71931.1 - 0.72 10.0 3.5 1.6 8.8 3.5 1.6 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Adeno_E3_CR2 PF02439.15 CCC71931.1 - 1.1 9.1 5.2 2.4 8.0 5.2 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GFA PF04828.14 CCC71932.1 - 0.014 15.7 0.2 0.024 15.0 0.2 1.4 1 0 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme Tmemb_9 PF05434.11 CCC71932.1 - 0.34 10.8 2.6 0.55 10.1 2.3 1.4 1 1 0 1 1 1 0 TMEM9 PAP2 PF01569.21 CCC71934.1 - 1.7e-16 60.2 4.1 4.2e-16 59.0 4.1 1.7 1 0 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 CCC71934.1 - 0.21 11.7 1.8 5 7.3 0.0 2.9 3 0 0 3 3 3 0 Divergent PAP2 family Ribosomal_S21e PF01249.18 CCC71935.1 - 2.7e-39 133.1 0.1 3e-39 133.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Glyco_hydro2_C5 PF18565.1 CCC71935.1 - 0.026 14.4 0.1 0.031 14.1 0.1 1.1 1 0 0 1 1 1 0 Glycoside hydrolase family 2 C-terminal domain 5 VCH_CASS14 PF18315.1 CCC71935.1 - 0.049 13.7 0.0 0.084 12.9 0.0 1.5 1 1 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain Pkinase PF00069.25 CCC71936.1 - 1.5e-49 168.8 0.2 2e-48 165.0 0.2 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71936.1 - 2.3e-20 73.0 0.0 4.5e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 CCC71936.1 - 0.0046 16.6 0.5 0.014 15.0 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 CCC71936.1 - 0.02 14.8 0.2 0.08 12.8 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Tim17 PF02466.19 CCC71937.1 - 7.8e-32 109.9 5.4 9.9e-32 109.6 5.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PHC2_SAM_assoc PF16616.5 CCC71938.1 - 0.024 15.5 1.3 0.025 15.4 0.2 1.5 2 0 0 2 2 2 0 Unstructured region on Polyhomeotic-like protein 1 and 2 CRAL_TRIO PF00650.20 CCC71939.1 - 8.2e-26 90.6 0.9 8.2e-26 90.6 0.9 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCC71939.1 - 0.05 13.8 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain ATP-synt_E_2 PF08112.11 CCC71941.1 - 1 9.7 10.9 2.5 8.4 0.1 3.3 4 0 0 4 4 4 0 ATP synthase epsilon subunit F-box-like PF12937.7 CCC71942.1 - 5.9e-09 35.7 0.1 2e-08 34.0 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 CCC71942.1 - 3e-07 30.2 0.3 1.8e-05 24.5 0.0 2.9 2 0 0 2 2 2 1 F-box domain CENP-B_dimeris PF09026.10 CCC71942.1 - 3.7 8.0 10.0 0.62 10.5 5.8 1.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NAD_binding_5 PF07994.12 CCC71943.1 - 3.3e-144 480.2 0.1 3.9e-144 479.9 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 CCC71943.1 - 1.9e-43 147.1 0.3 4e-43 146.1 0.3 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase KAsynt_C_assoc PF16197.5 CCC71943.1 - 0.094 13.2 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Vps35 PF03635.17 CCC71944.1 - 1.2e-214 715.1 41.5 1.4e-214 714.8 41.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 6PF2K PF01591.18 CCC71945.1 - 3.3e-77 258.7 3.2 5e-77 258.2 3.2 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 CCC71945.1 - 8e-39 133.4 0.0 1.2e-38 132.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 CCC71945.1 - 0.0093 16.1 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Peptidase_S64 PF08192.11 CCC71946.1 - 3.1e-281 935.0 7.3 3.5e-281 934.8 7.3 1.0 1 0 0 1 1 1 1 Peptidase family S64 zf-RING_2 PF13639.6 CCC71947.1 - 0.026 14.9 4.0 0.087 13.2 4.0 2.0 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 CCC71947.1 - 0.31 11.1 3.9 0.68 9.9 3.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 CCC71947.1 - 1.2 9.1 4.2 3.3 7.6 4.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 CCC71947.1 - 1.5 8.5 6.4 0.41 10.3 2.7 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 CCC71947.1 - 1.8 8.6 4.2 13 5.8 0.6 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_11 PF17123.5 CCC71947.1 - 2.2 8.1 7.6 0.93 9.3 3.0 2.7 3 0 0 3 3 3 0 RING-like zinc finger PIR PF00399.19 CCC71948.1 - 5.3e-06 25.8 1.4 5.3e-06 25.8 1.4 2.7 3 0 0 3 3 3 1 Yeast PIR protein repeat PIR PF00399.19 CCC71949.1 - 1.1e-53 177.7 102.6 6.9e-09 35.0 6.2 8.1 7 0 0 7 7 7 7 Yeast PIR protein repeat DUF374 PF04028.13 CCC71949.1 - 0.00013 21.4 3.4 39 3.9 0.0 5.8 2 1 4 6 6 6 1 Domain of unknown function (DUF374) DUF2072 PF09845.9 CCC71949.1 - 0.089 13.1 2.7 0.55 10.5 2.7 2.1 1 1 0 1 1 1 0 Zn-ribbon containing protein TFIIA PF03153.13 CCC71949.1 - 0.61 10.0 16.8 0.7 9.8 16.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PIR PF00399.19 CCC71950.1 - 1.2e-07 31.1 10.2 3.3e-05 23.3 0.9 2.7 2 0 0 2 2 2 2 Yeast PIR protein repeat Elf1 PF05129.13 CCC71950.1 - 0.0072 16.3 0.9 0.014 15.5 0.9 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like DUF4519 PF15012.6 CCC71950.1 - 0.45 10.7 5.8 1 9.6 5.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) YfhO PF09586.10 CCC71950.1 - 1.4 7.1 8.7 2.1 6.5 8.7 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DUF2369 PF10179.9 CCC71950.1 - 6 7.3 11.4 29 5.1 0.2 2.3 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2369) DnaJ PF00226.31 CCC71951.1 - 9.3e-20 70.5 0.4 3.5e-19 68.7 0.4 2.1 1 0 0 1 1 1 1 DnaJ domain PagP PF07017.11 CCC71951.1 - 0.1 12.0 0.1 0.24 10.8 0.1 1.7 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP Pkinase PF00069.25 CCC71952.1 - 8.3e-72 241.7 0.0 1e-71 241.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71952.1 - 3.9e-40 137.8 0.0 5e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 CCC71952.1 - 2.4e-05 23.8 0.0 5.1e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 CCC71952.1 - 0.018 14.7 0.0 0.75 9.4 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 CCC71952.1 - 0.079 11.9 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 CCC71952.1 - 0.086 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 CCC71952.1 - 0.16 11.3 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 CCC71953.1 - 5.1e-45 153.9 0.4 1.8e-44 152.1 0.4 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71953.1 - 1.5e-18 67.1 0.0 2.6e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 CCC71953.1 - 0.027 13.8 0.1 0.069 12.5 0.1 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DHC PF09626.10 CCC71953.1 - 0.039 14.8 0.9 3.3 8.6 0.1 2.9 2 0 0 2 2 2 0 Dihaem cytochrome c RIO1 PF01163.22 CCC71953.1 - 0.086 12.4 0.0 0.39 10.3 0.0 2.0 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 CCC71953.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family UcrQ PF02939.16 CCC71954.1 - 3.3e-33 113.5 2.0 3.8e-33 113.3 2.0 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 CCC71954.1 - 0.00044 20.6 0.1 0.00059 20.2 0.1 1.3 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 Ebp2 PF05890.12 CCC71955.1 - 3.2e-87 292.5 26.3 3.2e-87 292.5 26.3 3.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 SRI PF08236.11 CCC71956.1 - 1.9e-22 79.3 7.6 1.9e-22 79.3 7.6 2.6 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain WW_1 PF18507.1 CCC71956.1 - 3.7e-17 61.7 2.1 3.7e-17 61.7 2.1 1.8 2 0 0 2 2 2 1 WW domain SET PF00856.28 CCC71956.1 - 5.6e-17 62.6 0.9 5.6e-17 62.6 0.9 4.8 3 2 0 3 3 3 1 SET domain AWS PF17907.1 CCC71956.1 - 1.4e-14 53.8 10.3 1.4e-14 53.8 10.3 2.0 2 0 0 2 2 2 1 AWS domain Phage_X PF05155.15 CCC71956.1 - 0.002 18.5 0.1 0.0065 16.9 0.1 1.9 1 0 0 1 1 1 1 Phage X family Prok-E2_B PF14461.6 CCC71956.1 - 0.06 13.1 0.0 0.21 11.3 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B Peptidase_M20 PF01546.28 CCC71958.1 - 8.7e-38 130.1 0.0 1.6e-37 129.2 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 CCC71958.1 - 2e-17 63.1 0.3 4.3e-16 58.8 0.3 2.3 1 1 0 1 1 1 1 Peptidase dimerisation domain Rep_fac-A_3 PF08661.11 CCC71959.1 - 2.3e-22 79.3 0.0 2.7e-22 79.1 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 KRE9 PF05390.11 CCC71960.1 - 1.4e-49 167.0 10.0 1.4e-49 167.0 10.0 2.5 3 0 0 3 3 3 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CCC71960.1 - 5.4e-11 43.1 3.4 5.4e-11 43.1 3.4 2.6 2 2 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CLPTM1 PF05602.12 CCC71960.1 - 0.011 14.8 0.0 0.02 14.0 0.0 1.5 1 1 0 1 1 1 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF1425 PF07233.12 CCC71960.1 - 0.091 12.7 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) SWIRM PF04433.17 CCC71961.1 - 3.8e-27 94.5 0.5 3.8e-27 94.5 0.5 2.7 2 0 0 2 2 2 1 SWIRM domain SWIRM-assoc_1 PF16495.5 CCC71961.1 - 1.3e-22 79.5 10.5 1.3e-22 79.5 10.5 2.3 2 0 0 2 2 2 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 CCC71961.1 - 3.6e-11 43.1 0.0 1.1e-10 41.5 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 CCC71961.1 - 6.3e-10 39.2 3.2 9e-10 38.7 0.1 2.9 2 1 0 2 2 2 1 Myb-like DNA-binding domain Ribosomal_L22 PF00237.19 CCC71962.1 - 2.5e-38 130.4 1.7 2.5e-38 130.4 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e CRT10 PF08728.10 CCC71962.1 - 0.14 10.3 0.2 0.16 10.1 0.2 1.0 1 0 0 1 1 1 0 CRT10 ATG27 PF09451.10 CCC71963.1 - 9.8e-49 166.6 0.3 1.2e-48 166.2 0.3 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 PBP1_TM PF14812.6 CCC71963.1 - 0.044 14.2 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prefoldin_2 PF01920.20 CCC71964.1 - 1.3e-13 50.8 7.1 1.4e-13 50.7 7.1 1.0 1 0 0 1 1 1 1 Prefoldin subunit ATP12 PF07542.11 CCC71965.1 - 8.4e-34 116.4 0.1 2.5e-32 111.7 0.0 2.2 2 0 0 2 2 2 2 ATP12 chaperone protein Glyco_transf_34 PF05637.12 CCC71966.1 - 5.1e-53 180.3 0.1 7.7e-53 179.7 0.1 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF746 PF05344.11 CCC71966.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Gon7 PF08738.10 CCC71967.1 - 1.6e-42 143.9 0.4 2.3e-42 143.5 0.4 1.2 1 0 0 1 1 1 1 Gon7 family NUC153 PF08159.12 CCC71967.1 - 0.035 13.9 0.0 0.067 13.0 0.0 1.5 1 0 0 1 1 1 0 NUC153 domain muHD PF10291.9 CCC71969.1 - 2e-73 247.1 0.0 4.2e-73 246.0 0.0 1.6 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.23 CCC71969.1 - 0.013 15.7 0.5 0.045 14.0 0.5 1.9 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain Sigma54_activ_2 PF14532.6 CCC71969.1 - 0.034 14.3 0.2 0.095 12.8 0.2 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Torsin PF06309.11 CCC71969.1 - 0.054 13.6 0.0 0.25 11.4 0.0 2.2 1 0 0 1 1 1 0 Torsin Pkinase PF00069.25 CCC71970.1 - 1.5e-47 162.2 0.1 3.1e-47 161.2 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 CCC71970.1 - 4.4e-27 95.0 0.0 6.9e-27 94.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4299 PF14132.6 CCC71970.1 - 0.0012 18.3 2.0 0.0025 17.3 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4299) Kinase-like PF14531.6 CCC71970.1 - 0.094 12.0 0.0 0.94 8.7 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Ribosomal_L39 PF00832.20 CCC71972.1 - 3.1e-23 81.1 11.8 3.7e-23 80.9 11.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Ribosomal_S8 PF00410.19 CCC71973.1 - 3.5e-24 85.2 0.1 4.9e-24 84.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S11 PF00411.19 CCC71974.1 - 4.9e-46 155.7 1.8 6e-46 155.4 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 BKACE PF05853.12 CCC71974.1 - 0.045 13.1 0.4 0.055 12.8 0.4 1.1 1 0 0 1 1 1 0 beta-keto acid cleavage enzyme Op_neuropeptide PF08035.11 CCC71975.1 - 0.0061 16.4 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Opioids neuropeptide CwfJ_C_2 PF04676.14 CCC71976.1 - 0.063 14.2 0.2 0.16 12.8 0.2 1.4 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 2 SOP4 PF17081.5 CCC71977.1 - 1.4e-99 331.8 0.8 1.7e-99 331.6 0.8 1.0 1 0 0 1 1 1 1 Suppressor of PMA 1-7 protein TPT PF03151.16 CCC71978.1 - 3.4e-36 125.1 11.3 3.1e-18 66.2 4.2 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 CCC71978.1 - 0.089 13.0 42.5 0.067 13.4 14.4 3.9 2 2 0 3 3 3 0 EamA-like transporter family AAA PF00004.29 CCC71979.1 - 3.6e-10 40.4 0.0 1.6e-09 38.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCC71979.1 - 1.3e-09 38.4 0.0 1.1e-08 35.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 CCC71979.1 - 3.5e-09 37.3 0.0 2.6e-08 34.4 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain Cdc6_C PF09079.11 CCC71979.1 - 5e-09 36.0 0.1 1.2e-08 34.8 0.1 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain TniB PF05621.11 CCC71979.1 - 7e-05 22.3 0.0 0.0035 16.8 0.0 2.3 1 1 0 1 1 1 1 Bacterial TniB protein AAA_19 PF13245.6 CCC71979.1 - 0.0045 17.3 0.3 0.38 11.1 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.6 CCC71979.1 - 0.018 14.8 0.2 0.14 11.9 0.0 2.5 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_7 PF12775.7 CCC71979.1 - 0.025 14.1 0.1 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_11 PF13086.6 CCC71979.1 - 0.082 12.7 3.6 0.78 9.5 0.0 3.2 3 1 0 4 4 4 0 AAA domain T2SSE PF00437.20 CCC71979.1 - 0.12 11.4 0.0 0.75 8.8 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein YozE_SAM_like PF06855.12 CCC71979.1 - 0.18 12.0 1.0 12 6.1 0.0 2.8 2 0 0 2 2 2 0 YozE SAM-like fold Myb_DNA-binding PF00249.31 CCC71980.1 - 0.00042 20.5 0.2 0.0014 18.8 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain ELO PF01151.18 CCC71981.1 - 1.8e-61 207.9 25.9 2.3e-61 207.5 25.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family UCH PF00443.29 CCC71982.1 - 6e-78 261.9 0.0 7.5e-77 258.3 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 CCC71982.1 - 1.3e-14 54.5 7.8 1.8e-06 27.8 4.6 3.5 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 CCC71982.1 - 1.5e-06 28.7 0.2 1.5e-06 28.7 0.2 3.6 3 1 0 3 3 3 1 DUSP domain SPX PF03105.19 CCC71983.1 - 4.4e-45 155.2 11.8 1.1e-44 153.9 11.8 1.6 1 1 0 1 1 1 1 SPX domain CitMHS PF03600.16 CCC71983.1 - 2.5e-22 79.4 48.8 1.8e-16 60.2 21.8 2.1 1 1 1 2 2 2 2 Citrate transporter Na_sulph_symp PF00939.19 CCC71983.1 - 4e-16 59.1 39.4 5.5e-16 58.7 39.4 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region RFX_DNA_binding PF02257.15 CCC71983.1 - 0.24 12.1 0.8 37 5.0 0.1 2.4 2 0 0 2 2 2 0 RFX DNA-binding domain Sugar_tr PF00083.24 CCC71984.1 - 3.7e-161 537.0 34.6 4.2e-161 536.8 34.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC71984.1 - 3.8e-30 105.0 36.3 2.5e-26 92.4 23.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 CCC71984.1 - 0.026 12.9 7.5 0.006 15.0 4.0 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector Flo11 PF10182.9 CCC71986.1 - 2.4e-63 212.7 2.8 2.1e-62 209.7 2.8 2.8 1 0 0 1 1 1 1 Flo11 domain CadC_C1 PF18500.1 CCC71987.1 - 0.011 15.8 0.2 0.016 15.3 0.2 1.2 1 0 0 1 1 1 0 CadC C-terminal domain 1 Sugar_tr PF00083.24 CCC71989.1 - 5.2e-168 559.6 31.2 6e-168 559.4 31.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC71989.1 - 2.3e-26 92.6 28.2 3.2e-26 92.1 19.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 CCC71989.1 - 0.043 14.1 4.4 0.38 11.1 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) DUF2530 PF10745.9 CCC71989.1 - 7.2 6.9 7.1 2.4 8.4 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) DUF3589 PF12141.8 CCC71990.1 - 6.3e-93 312.0 0.9 3e-57 194.3 0.0 2.5 2 1 0 2 2 2 2 Beta-mannosyltransferases GST_N_2 PF13409.6 CCC71991.1 - 8.8e-16 58.0 1.4 6.4e-15 55.2 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 CCC71991.1 - 5.7e-07 29.5 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 CCC71991.1 - 0.11 12.9 0.0 0.37 11.2 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Sugar_tr PF00083.24 CCC71992.1 - 1.7e-168 561.1 32.0 2e-168 560.9 32.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC71992.1 - 4.8e-27 94.8 27.8 1.2e-26 93.5 19.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 CCC71992.1 - 0.035 14.4 3.3 0.28 11.5 0.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) AA_permease PF00324.21 CCC71994.1 - 1.5e-115 386.6 35.7 1.8e-115 386.3 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 CCC71994.1 - 7.2e-37 127.2 40.0 8.8e-37 126.9 40.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2845 PF11006.8 CCC71994.1 - 0.18 12.0 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) Lactamase_B_2 PF12706.7 CCC71995.1 - 3.3e-12 46.4 0.0 7.6e-12 45.2 0.0 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 CCC71995.1 - 3.9e-11 43.1 0.0 5.5e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 CCC71995.1 - 0.011 15.7 0.9 0.052 13.6 0.2 2.1 2 1 0 2 2 2 0 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 CCC71995.1 - 0.019 14.4 0.1 0.098 12.1 0.0 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily domain Bact_lectin PF18483.1 CCC71995.1 - 0.031 14.3 0.1 0.043 13.8 0.1 1.2 1 0 0 1 1 1 0 Bacterial lectin ABC_tran PF00005.27 CCC71996.1 - 6.1e-59 198.4 0.3 2.3e-34 118.8 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 CCC71996.1 - 3.4e-54 184.4 35.9 5.2e-35 121.4 12.4 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region SMC_N PF02463.19 CCC71996.1 - 1.2e-10 41.2 7.3 9.5e-07 28.5 0.8 4.1 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCC71996.1 - 8.1e-10 39.5 2.5 0.00019 22.0 0.2 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.6 CCC71996.1 - 1.3e-09 38.3 0.4 0.004 17.0 0.0 3.6 2 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 CCC71996.1 - 1.2e-07 31.8 4.4 0.0057 16.4 1.4 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 CCC71996.1 - 4.5e-07 29.5 0.6 0.0053 16.5 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 CCC71996.1 - 6.5e-07 29.4 0.2 0.0062 16.5 0.0 2.8 3 0 0 3 3 2 2 RsgA GTPase MMR_HSR1 PF01926.23 CCC71996.1 - 3.9e-05 23.7 5.8 0.0061 16.6 0.3 3.4 3 1 0 3 3 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 CCC71996.1 - 5.2e-05 22.5 0.1 0.01 14.9 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_22 PF13401.6 CCC71996.1 - 0.00013 22.2 0.0 0.96 9.7 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 CCC71996.1 - 0.00037 20.9 0.0 1.6 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 CCC71996.1 - 0.00053 19.8 0.1 0.029 14.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.17 CCC71996.1 - 0.00057 20.1 1.4 0.87 9.6 0.0 3.3 3 0 0 3 3 3 1 Helicase HerA, central domain Zeta_toxin PF06414.12 CCC71996.1 - 0.00085 18.7 0.0 0.38 10.0 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA_7 PF12775.7 CCC71996.1 - 0.0019 17.8 0.1 1 8.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA PF00004.29 CCC71996.1 - 0.0019 18.6 0.0 1.5 9.2 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.17 CCC71996.1 - 0.0032 17.3 0.0 8.6 6.1 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 CCC71996.1 - 0.0058 16.7 1.6 1.2 9.1 0.1 3.0 3 0 0 3 3 3 1 Dynamin family Roc PF08477.13 CCC71996.1 - 0.0063 16.7 1.5 17 5.6 0.0 3.6 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 CCC71996.1 - 0.0083 15.5 0.3 4.1 6.7 0.1 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_30 PF13604.6 CCC71996.1 - 0.0095 15.7 0.0 7 6.3 0.0 2.7 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 CCC71996.1 - 0.014 15.0 0.2 0.7 9.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 CCC71996.1 - 0.014 15.4 0.0 5.6 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain CbiA PF01656.23 CCC71996.1 - 0.015 15.4 0.0 30 4.7 0.0 3.6 3 1 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Guanylate_kin PF00625.21 CCC71996.1 - 0.017 14.8 0.2 1.7 8.3 0.0 3.1 3 0 0 3 3 3 0 Guanylate kinase AAA_25 PF13481.6 CCC71996.1 - 0.027 14.0 0.1 0.74 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 CCC71996.1 - 0.065 13.4 0.0 4.6 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 CCC71996.1 - 0.067 13.7 0.0 25 5.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 CCC71996.1 - 0.093 11.6 0.1 6.1 5.7 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain RhodobacterPufX PF11511.8 CCC71996.1 - 0.14 11.8 1.1 10 5.8 0.1 3.5 3 0 0 3 3 2 0 Intrinsic membrane protein PufX IstB_IS21 PF01695.17 CCC71996.1 - 0.17 11.6 0.9 8.4 6.1 0.0 2.8 3 0 0 3 3 3 0 IstB-like ATP binding protein Sugar_tr PF00083.24 CCC71997.1 - 1.8e-160 534.7 30.0 2e-160 534.6 30.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 CCC71997.1 - 3.3e-32 111.8 30.2 1.5e-31 109.7 21.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 CCC71997.1 - 0.00023 19.8 2.4 0.00043 18.8 2.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.13 CCC71997.1 - 0.00094 17.7 0.3 0.00094 17.7 0.3 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector DUF3589 PF12141.8 CCC71998.1 - 6.1e-72 242.8 0.1 4.9e-69 233.2 0.1 2.6 1 1 0 1 1 1 1 Beta-mannosyltransferases ADH_N_2 PF16884.5 CCC71999.1 - 2.8e-20 72.2 0.0 5e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 CCC71999.1 - 7.6e-16 58.3 0.4 1.2e-15 57.6 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase LAB_N PF07578.11 CCC71999.1 - 0.021 14.9 0.5 0.045 13.8 0.5 1.5 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain DUF3589 PF12141.8 CCC72000.1 - 6e-72 242.8 0.1 4.9e-69 233.2 0.1 2.5 1 1 0 1 1 1 1 Beta-mannosyltransferases DUF4029 PF13221.6 CCC72000.1 - 0.12 13.1 0.1 0.98 10.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4029) Lectin_leg-like PF03388.13 CCC72001.1 - 5.4e-46 156.8 0.1 8.3e-46 156.2 0.1 1.2 1 0 0 1 1 1 1 Legume-like lectin family Bact_lectin PF18483.1 CCC72001.1 - 0.00094 19.2 0.0 0.0043 17.1 0.0 2.0 1 1 0 1 1 1 1 Bacterial lectin BAR_3 PF16746.5 CCC72001.1 - 0.074 12.7 3.2 0.13 12.0 3.2 1.3 1 0 0 1 1 1 0 BAR domain of APPL family Methyltransf_31 PF13847.6 CCC72001.1 - 0.097 12.5 0.1 0.16 11.8 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Fib_alpha PF08702.10 CCC72001.1 - 0.15 12.2 3.6 0.25 11.5 3.1 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family PikAIV_N PF18605.1 CCC72001.1 - 0.24 11.0 1.7 0.48 10.0 1.7 1.5 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF3461 PF11944.8 CCC72001.1 - 0.65 10.1 5.2 2.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) V_ATPase_I PF01496.19 CCC72002.1 - 0.042 11.8 1.1 0.061 11.2 1.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family V-SNARE_C PF12352.8 CCC72003.1 - 8.5e-08 32.4 1.2 2.5e-07 30.9 1.2 1.9 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 CCC72003.1 - 0.0034 17.2 1.0 0.0034 17.2 1.0 2.1 2 1 0 2 2 2 1 Sec20 Tup_N PF08581.10 CCC72003.1 - 0.056 13.7 0.6 0.15 12.3 0.1 2.0 2 0 0 2 2 2 0 Tup N-terminal CLZ PF16526.5 CCC72003.1 - 0.065 13.6 0.4 0.28 11.6 0.2 2.2 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4407 PF14362.6 CCC72003.1 - 0.32 10.3 5.3 0.67 9.2 5.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) RCC1 PF00415.18 CCC72004.1 - 7.2e-20 71.4 0.6 7.7e-05 23.2 0.1 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 CCC72004.1 - 6.4e-15 54.5 10.9 5.2e-09 35.7 0.5 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Ribosomal_L16 PF00252.18 CCC72005.1 - 3.2e-41 140.4 0.1 4e-41 140.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-C2H2_jaz PF12171.8 CCC72006.1 - 1.2e-08 35.0 6.9 1.2e-08 35.0 6.9 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 CCC72006.1 - 0.00044 20.5 0.3 0.00086 19.6 0.3 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2HE PF16278.5 CCC72006.1 - 1.5 9.3 6.3 9.9 6.7 3.6 2.9 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger OTU PF02338.19 CCC72007.1 - 7e-07 29.8 0.0 1.2e-06 29.1 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF4934 PF16288.5 CCC72007.1 - 0.04 13.8 0.2 0.08 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4934) zf-C2H2_2 PF12756.7 CCC72007.1 - 0.096 13.0 0.3 0.21 12.0 0.2 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) VASt PF16016.5 CCC72008.1 - 2.4e-33 115.7 0.7 9.3e-33 113.8 0.2 2.3 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 CCC72008.1 - 5.9e-25 87.4 0.0 1.4e-24 86.2 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Med14 PF08638.11 CCC72009.1 - 1.6e-56 190.7 1.9 1.6e-56 190.7 1.9 2.2 2 0 0 2 2 2 1 Mediator complex subunit MED14 ADH_zinc_N PF00107.26 CCC72010.1 - 3.2e-27 95.1 0.1 5.3e-27 94.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 CCC72010.1 - 5.4e-27 93.8 0.2 1.3e-26 92.6 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Glu_dehyd_C PF16912.5 CCC72010.1 - 8.7e-10 38.4 0.2 2.3e-09 37.0 0.2 1.7 1 1 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 CCC72010.1 - 1.3e-07 32.8 0.0 2.2e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 CCC72010.1 - 0.0021 17.4 0.8 0.0035 16.7 0.8 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.14 CCC72010.1 - 0.058 13.0 0.2 0.094 12.3 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GTP_EFTU PF00009.27 CCC72011.1 - 2.8e-63 213.0 0.1 5.6e-63 212.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 CCC72011.1 - 1.1e-38 131.7 0.0 2.7e-38 130.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 CCC72011.1 - 8.6e-30 102.7 0.0 1.9e-29 101.5 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 CCC72011.1 - 3.4e-23 81.5 0.0 7.1e-23 80.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 CCC72011.1 - 2.1e-13 50.5 0.3 5e-13 49.2 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 CCC72011.1 - 2.4e-06 27.4 0.0 7.7e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain AvrPtoB_bdg PF16847.5 CCC72011.1 - 0.00021 21.7 0.0 0.0057 17.1 0.0 2.6 2 0 0 2 2 2 1 Avirulence AvrPtoB, BAK1-binding domain MMR_HSR1 PF01926.23 CCC72011.1 - 0.0085 16.2 0.0 0.025 14.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF442 PF04273.13 CCC72011.1 - 0.12 12.4 0.0 3.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) rRNA_processing PF08524.11 CCC72012.1 - 6.6e-39 133.3 38.5 7.6e-39 133.1 38.5 1.0 1 0 0 1 1 1 1 rRNA processing Coilin_N PF15862.5 CCC72012.1 - 1.6 8.5 16.5 28 4.5 16.5 2.3 1 1 0 1 1 1 0 Coilin N-terminus PPR_2 PF13041.6 CCC72013.1 - 1.8e-12 47.2 12.1 0.02 15.1 0.0 9.1 6 4 4 10 10 10 4 PPR repeat family PPR PF01535.20 CCC72013.1 - 3.1e-12 45.8 5.9 0.071 13.4 0.0 9.5 10 0 0 10 10 10 2 PPR repeat PPR_long PF17177.4 CCC72013.1 - 7.2e-08 32.1 2.0 1.5 8.1 0.0 4.0 3 1 0 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR_3 PF13812.6 CCC72013.1 - 0.0039 17.2 2.7 2.3 8.4 0.0 4.5 4 1 0 4 4 4 1 Pentatricopeptide repeat domain TPR_14 PF13428.6 CCC72013.1 - 0.012 16.3 0.0 26 6.0 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat LEDGF PF11467.8 CCC72013.1 - 0.02 14.5 0.6 0.22 11.2 0.2 2.8 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) TPR_19 PF14559.6 CCC72013.1 - 0.037 14.5 0.2 1.9 9.1 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Vps39_1 PF10366.9 CCC72013.1 - 0.038 14.3 0.7 1.2 9.4 0.1 3.7 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 1 rve PF00665.26 CCC72014.1 - 0.00013 22.1 0.0 0.00017 21.8 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain Hyphal_reg_CWP PF11765.8 CCC72017.1 - 3.2e-11 42.7 15.9 8.7e-11 41.3 15.9 1.7 1 0 0 1 1 1 1 Hyphally regulated cell wall protein N-terminal Tubulin PF00091.25 CCC72018.1 - 1.2e-66 224.7 0.0 2.3e-66 223.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 CCC72018.1 - 3.7e-42 143.5 0.2 2.1e-41 141.0 0.1 2.0 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 CCC72018.1 - 0.00098 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 CCC72018.1 - 0.014 15.7 0.0 0.037 14.3 0.0 1.8 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 CCC72018.1 - 0.053 12.7 0.0 0.14 11.4 0.0 1.7 1 0 0 1 1 1 0 Tubulin like Methyltransf_34 PF11312.8 CCC72019.1 - 9.7e-89 297.6 0.0 1.2e-88 297.4 0.0 1.1 1 0 0 1 1 1 1 Putative SAM-dependent methyltransferase CheR PF01739.18 CCC72019.1 - 0.01 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Ribosomal_L22e PF01776.17 CCC72020.1 - 3.2e-40 136.9 0.4 4.1e-40 136.6 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF4799 PF16056.5 CCC72020.1 - 0.047 12.8 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4799) RNase_T PF00929.24 CCC72021.1 - 4.5e-33 115.1 0.4 6.8e-33 114.5 0.4 1.3 1 0 0 1 1 1 1 Exonuclease DUF2237 PF09996.9 CCC72021.1 - 0.022 14.7 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) Glyco_hydro_47 PF01532.20 CCC72022.1 - 1.6e-77 261.4 0.5 2.8e-77 260.6 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 WD40 PF00400.32 CCC72025.1 - 3e-08 34.2 2.3 0.74 10.8 0.1 6.3 7 0 0 7 7 7 2 WD domain, G-beta repeat Macoilin PF09726.9 CCC72025.1 - 1.3 7.4 12.3 1.9 6.9 12.3 1.2 1 0 0 1 1 1 0 Macoilin family ApbA_C PF08546.11 CCC72026.1 - 0.026 14.7 0.0 0.082 13.1 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Fcf2 PF08698.11 CCC72028.1 - 4.2e-32 110.4 0.9 4.2e-32 110.4 0.9 2.2 3 0 0 3 3 3 1 Fcf2 pre-rRNA processing Pyr_redox_2 PF07992.14 CCC72029.1 - 2.4e-65 220.7 6.2 3.3e-65 220.2 6.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 CCC72029.1 - 6.4e-42 142.3 0.0 2.1e-41 140.6 0.0 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 CCC72029.1 - 4.5e-21 75.2 6.9 3.4e-18 66.0 1.4 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 CCC72029.1 - 7.2e-14 52.0 0.5 2.1e-10 40.5 0.2 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 CCC72029.1 - 1.3e-08 34.4 8.6 1.2e-05 24.7 0.5 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 CCC72029.1 - 2.9e-08 33.8 4.2 0.00029 21.0 1.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 CCC72029.1 - 3e-07 29.9 2.9 3e-07 29.9 2.9 2.7 2 1 1 3 3 3 1 FAD binding domain GIDA PF01134.22 CCC72029.1 - 3.8e-07 29.5 10.2 1.1e-06 28.0 7.7 2.6 1 1 1 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 CCC72029.1 - 2e-05 24.0 8.4 0.0083 15.4 0.9 3.4 2 1 0 3 3 3 2 FAD binding domain HI0933_like PF03486.14 CCC72029.1 - 8.5e-05 21.4 14.4 0.00029 19.7 1.2 3.8 3 1 1 4 4 4 2 HI0933-like protein K_oxygenase PF13434.6 CCC72029.1 - 0.00015 21.0 1.3 0.059 12.5 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 CCC72029.1 - 0.0003 20.1 2.8 0.0013 18.0 0.1 2.3 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.21 CCC72029.1 - 0.0012 18.2 5.8 0.29 10.4 0.3 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain PTS_IIB PF02302.17 CCC72029.1 - 0.039 14.6 1.2 8.2 7.2 0.1 3.0 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit AIRC PF00731.20 CCC72029.1 - 0.047 13.3 0.0 0.19 11.3 0.0 2.0 2 0 0 2 2 2 0 AIR carboxylase THF_DHG_CYH_C PF02882.19 CCC72029.1 - 0.053 12.8 0.2 0.21 10.9 0.2 2.0 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Glyco_hydro_3_C PF01915.22 CCC72029.1 - 0.087 12.8 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 3 C-terminal domain DAO PF01266.24 CCC72029.1 - 0.36 10.4 18.4 0.19 11.3 0.3 3.8 3 1 1 4 4 4 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 CCC72029.1 - 1.1 9.1 6.5 0.11 12.3 0.7 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 CCC72029.1 - 3.7 6.5 5.3 1.2 8.2 0.8 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein WW PF00397.26 CCC72031.1 - 1.5e-10 41.0 0.8 3.4e-10 39.8 0.8 1.7 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.9 CCC72031.1 - 0.033 14.2 43.3 0.74 9.8 43.0 2.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) TFIIA PF03153.13 CCC72031.1 - 0.12 12.3 12.2 0.14 12.1 12.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 CCC72031.1 - 0.26 11.9 25.1 0.73 10.5 25.2 1.7 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PRY PF13765.6 CCC72031.1 - 0.46 10.2 1.5 0.92 9.2 1.5 1.5 1 0 0 1 1 1 0 SPRY-associated domain PAT1 PF09770.9 CCC72031.1 - 2.7 6.2 8.8 2.8 6.1 8.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DAO PF01266.24 CCC72032.1 - 8.6e-16 58.4 0.0 1.4e-15 57.8 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase REC104 PF17378.2 CCC72035.1 - 0.029 14.2 0.1 0.046 13.5 0.1 1.4 1 0 0 1 1 1 0 Meiotic recombination protein REC104 REC104 PF17378.2 CCC72036.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Meiotic recombination protein REC104 FHA PF00498.26 CCC72036.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 FHA domain DEAD PF00270.29 CCC72037.1 - 1e-39 136.1 0.1 2.1e-39 135.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 CCC72037.1 - 5.5e-23 81.4 0.2 3.2e-22 79.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 CCC72037.1 - 4.4e-16 58.9 0.1 1.1e-15 57.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 CCC72037.1 - 6.1e-06 26.3 0.0 6.1e-06 26.3 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 CCC72037.1 - 0.0012 18.1 0.0 0.0012 18.1 0.0 2.5 3 1 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase ThiF PF00899.21 CCC72039.1 - 0.013 14.9 0.0 3.2 7.1 0.0 2.3 2 1 0 2 2 2 0 ThiF family Agglutinin PF07468.11 CCC72039.1 - 0.087 13.0 0.1 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 Agglutinin domain SIR2 PF02146.17 CCC72040.1 - 6.7e-53 179.2 0.0 9.4e-53 178.7 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Peptidase_C48 PF02902.19 CCC72041.1 - 1.4e-40 139.4 0.5 1.4e-40 139.4 0.5 2.4 3 1 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Ephrin PF00812.17 CCC72041.1 - 0.05 13.6 1.6 0.071 13.1 0.4 1.9 2 0 0 2 2 2 0 Ephrin Ras PF00071.22 CCC72042.1 - 2.3e-64 215.8 0.1 3e-64 215.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC72042.1 - 1.2e-36 125.6 0.1 1.9e-36 124.9 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 CCC72042.1 - 1.4e-18 67.0 0.2 1.8e-18 66.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 CCC72042.1 - 1.8e-07 31.2 0.6 0.01 15.7 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 CCC72042.1 - 4.2e-07 29.5 0.1 5.3e-07 29.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 CCC72042.1 - 6.7e-07 29.0 0.0 6.4e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 CCC72042.1 - 8.5e-07 28.6 0.1 1.1e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 CCC72042.1 - 2.8e-06 27.4 0.1 5e-06 26.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 CCC72042.1 - 0.00082 18.6 1.1 0.46 9.6 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit FeoB_N PF02421.18 CCC72042.1 - 0.0013 18.2 0.1 0.014 14.9 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 CCC72042.1 - 0.0023 18.2 0.2 0.049 13.9 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 CCC72042.1 - 0.0052 16.3 0.1 0.013 15.0 0.1 1.7 2 0 0 2 2 2 1 P-loop containing dynein motor region MCM PF00493.23 CCC72042.1 - 0.0071 15.5 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain DUF815 PF05673.13 CCC72042.1 - 0.018 14.2 0.0 0.049 12.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.6 CCC72042.1 - 0.025 14.3 0.0 0.076 12.8 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 CCC72042.1 - 0.045 14.1 0.1 0.098 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 CCC72042.1 - 0.087 12.5 0.0 0.48 10.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-C2H2 PF00096.26 CCC72043.1 - 1.9e-12 46.9 6.6 1.1e-05 25.7 0.2 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 CCC72043.1 - 2e-09 37.5 6.0 7.3e-07 29.3 0.2 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.6 CCC72043.1 - 1.5e-08 34.7 5.9 0.00052 20.6 0.2 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.6 CCC72043.1 - 0.0018 18.1 0.3 1.1 9.2 0.0 2.5 2 0 0 2 2 2 2 zinc-finger of a C2HC-type Ogr_Delta PF04606.12 CCC72043.1 - 0.0029 17.5 0.6 0.0041 17.1 0.6 1.2 1 0 0 1 1 1 1 Ogr/Delta-like zinc finger zf-met PF12874.7 CCC72043.1 - 0.0034 17.7 5.3 0.047 14.1 0.0 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 CCC72043.1 - 0.0043 17.3 0.4 0.6 10.5 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.10 CCC72043.1 - 0.0089 16.1 0.5 1.2 9.3 0.1 2.2 2 0 0 2 2 2 1 Zinc ribbon domain zf-ribbon_3 PF13248.6 CCC72043.1 - 0.027 13.9 0.6 0.18 11.2 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-tcix PF14952.6 CCC72043.1 - 0.028 14.0 2.3 2.5 7.8 0.2 2.2 2 0 0 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding PRP21_like_P PF12230.8 CCC72043.1 - 0.054 13.4 1.9 0.058 13.3 0.1 1.7 1 1 1 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein zf-Di19 PF05605.12 CCC72043.1 - 0.061 13.6 1.1 0.24 11.7 0.9 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding OrfB_Zn_ribbon PF07282.11 CCC72043.1 - 0.11 12.4 0.7 0.22 11.5 0.7 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-BED PF02892.15 CCC72043.1 - 0.12 12.4 4.3 0.15 12.1 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger zf-H2C2_5 PF13909.6 CCC72043.1 - 0.37 10.6 0.2 0.37 10.6 0.2 3.3 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-C2H2_11 PF16622.5 CCC72043.1 - 0.53 10.1 4.9 4.1 7.3 0.9 2.3 2 0 0 2 2 2 0 zinc-finger C2H2-type Pil1 PF13805.6 CCC72044.1 - 5.6e-124 412.9 0.6 6.6e-124 412.7 0.6 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.10 CCC72044.1 - 0.0063 16.7 0.3 0.16 12.2 0.3 2.8 2 0 0 2 2 2 1 Proto-chlorophyllide reductase 57 kD subunit PPR_2 PF13041.6 CCC72045.1 - 8.6e-08 32.3 9.0 0.0022 18.1 0.9 4.3 4 0 0 4 4 4 3 PPR repeat family PPR_3 PF13812.6 CCC72045.1 - 0.00033 20.7 1.0 0.48 10.5 0.4 3.1 3 0 0 3 3 3 2 Pentatricopeptide repeat domain Mpv17_PMP22 PF04117.12 CCC72046.1 - 4.3e-26 90.9 6.4 7.8e-26 90.1 6.4 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF5083 PF16890.5 CCC72046.1 - 0.0096 15.7 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5083) zf-TFIIIC PF12660.7 CCC72048.1 - 3.4e-08 33.4 0.1 1e-07 31.8 0.0 1.9 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.7 CCC72048.1 - 0.0036 17.3 0.1 0.012 15.5 0.1 1.9 1 0 0 1 1 1 1 Transcription factor IIIC subunit delta N-term DUF4384 PF14326.6 CCC72048.1 - 0.13 12.4 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4384) DUF5381 PF17353.2 CCC72048.1 - 0.21 11.3 1.8 0.45 10.2 1.0 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5381) DEAD_2 PF06733.15 CCC72049.1 - 1.2e-49 168.3 0.1 2.3e-49 167.4 0.1 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 CCC72049.1 - 2.1e-48 164.7 0.0 6e-48 163.2 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 CCC72049.1 - 3.6e-05 23.8 0.1 0.078 13.0 0.0 2.9 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DEAD PF00270.29 CCC72049.1 - 0.00031 20.6 0.0 0.066 13.0 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase AAA_22 PF13401.6 CCC72049.1 - 0.00036 20.8 0.2 0.048 13.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain PhoH PF02562.16 CCC72049.1 - 0.0048 16.4 0.2 0.47 9.9 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.29 CCC72049.1 - 0.19 12.2 0.8 3.4 8.1 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S16 PF00886.19 CCC72052.1 - 2.4e-25 88.4 0.0 3.4e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 PDR_assoc PF08370.11 CCC72052.1 - 0.18 11.5 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Ribosomal_L26 PF16906.5 CCC72053.1 - 1.2e-37 128.2 1.7 1.6e-37 127.9 1.7 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 CCC72053.1 - 0.00046 20.0 1.4 0.00059 19.7 0.4 1.7 2 0 0 2 2 2 1 KOW motif Glyco_hydro_72 PF03198.14 CCC72054.1 - 1.1e-137 458.5 7.4 1.6e-137 458.0 7.4 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.13 CCC72054.1 - 1.2e-14 54.7 0.2 3.1e-14 53.4 0.2 1.8 1 0 0 1 1 1 1 X8 domain Glyco_hydro_17 PF00332.18 CCC72054.1 - 0.014 15.0 0.1 0.026 14.1 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 HCO3_cotransp PF00955.21 CCC72054.1 - 0.019 13.8 1.2 0.029 13.2 1.2 1.2 1 0 0 1 1 1 0 HCO3- transporter family Glucan_synthase PF02364.15 CCC72055.1 - 0 1347.8 0.0 0 1347.3 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 CCC72055.1 - 4.7e-43 146.6 0.2 1.5e-42 145.0 0.2 1.9 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Spectrin PF00435.21 CCC72056.1 - 0.11 13.0 0.8 0.45 11.0 0.2 2.4 2 0 0 2 2 2 0 Spectrin repeat Fmp27_SW PF10305.9 CCC72056.1 - 0.34 11.6 5.8 4.5 8.0 0.0 3.7 4 1 0 4 4 4 0 RNA pol II promoter Fmp27 protein domain Ribosomal_S25 PF03297.15 CCC72057.1 - 1e-38 131.6 5.9 1.2e-38 131.4 5.9 1.0 1 0 0 1 1 1 1 S25 ribosomal protein FtsK_gamma PF09397.10 CCC72057.1 - 0.00075 19.2 0.1 0.0012 18.6 0.1 1.4 1 0 0 1 1 1 1 Ftsk gamma domain EAP30 PF04157.16 CCC72057.1 - 0.024 14.0 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family HTH_CodY PF08222.11 CCC72057.1 - 0.074 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain HTH_DeoR PF08220.12 CCC72057.1 - 0.097 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Ran_BP1 PF00638.18 CCC72058.1 - 1.3e-34 119.1 0.0 2.4e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.11 CCC72058.1 - 1.5e-13 51.1 2.7 1.5e-13 51.1 2.7 4.3 4 1 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) MA3 PF02847.17 CCC72059.1 - 1.4e-30 105.5 0.4 6.2e-30 103.5 0.3 2.2 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.19 CCC72059.1 - 2.4e-23 82.9 5.3 5.5e-23 81.7 5.3 1.7 1 0 0 1 1 1 1 MIF4G domain Evr1_Alr PF04777.13 CCC72060.1 - 1.2e-30 106.0 6.0 1.6e-30 105.5 5.2 1.6 2 0 0 2 2 2 1 Erv1 / Alr family WH2 PF02205.20 CCC72061.1 - 3e-12 45.9 7.9 4.6e-10 39.0 0.2 3.0 3 0 0 3 3 3 2 WH2 motif PWI PF01480.17 CCC72062.1 - 0.0066 16.7 0.7 0.028 14.7 0.4 2.2 2 0 0 2 2 2 1 PWI domain zf-NPL4 PF05020.15 CCC72062.1 - 0.83 9.8 4.2 0.96 9.6 0.0 2.9 3 0 0 3 3 3 0 NPL4 family, putative zinc binding region WSD PF15613.6 CCC72064.1 - 0.79 10.2 9.8 0.13 12.7 2.3 3.0 2 1 1 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif KASH_CCD PF14662.6 CCC72064.1 - 1.2 8.9 44.6 1.2 8.9 3.9 2.8 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH MF_alpha_N PF05436.11 CCC72065.1 - 5.3e-35 119.2 0.5 6.7e-35 118.9 0.5 1.1 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus MF_alpha PF04648.12 CCC72065.1 - 3.2e-21 74.7 33.4 7.9e-07 29.1 5.8 3.2 3 0 0 3 3 3 3 Yeast mating factor alpha hormone Mid2 PF04478.12 CCC72066.1 - 9.6e-62 207.2 0.7 9.6e-62 207.2 0.7 2.2 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor SKG6 PF08693.10 CCC72066.1 - 0.0039 16.6 3.5 0.025 14.0 3.5 2.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain fn3_2 PF16893.5 CCC72067.1 - 7.1e-39 131.8 0.4 1.3e-38 131.0 0.4 1.5 1 0 0 1 1 1 1 Fibronectin type III domain CHS5_N PF16892.5 CCC72067.1 - 3.5e-23 81.3 0.2 5.6e-23 80.6 0.2 1.3 1 0 0 1 1 1 1 Chitin biosynthesis protein CHS5 N-terminus BRCT PF00533.26 CCC72067.1 - 4.1e-11 43.1 0.2 1.3e-10 41.5 0.2 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DUF3006 PF11213.8 CCC72067.1 - 5.8e-05 23.2 2.5 0.00014 22.0 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3006) BRCT_2 PF16589.5 CCC72067.1 - 0.0011 19.3 0.1 0.003 17.9 0.1 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 CCC72067.1 - 0.0026 17.7 0.0 0.0056 16.6 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain fn3 PF00041.21 CCC72067.1 - 0.0072 16.7 0.0 0.021 15.2 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain BRCT_3 PF18428.1 CCC72067.1 - 0.066 13.3 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain CTP_transf_like PF01467.26 CCC72068.1 - 1.5e-31 109.5 0.0 2.3e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase-like DUF2184 PF09950.9 CCC72068.1 - 0.053 12.9 1.6 5.7 6.3 0.3 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2184) HABP4_PAI-RBP1 PF04774.15 CCC72070.1 - 0.0019 19.0 2.9 0.0028 18.5 2.9 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family DUF4112 PF13430.6 CCC72071.1 - 3.9e-30 104.2 0.3 5e-30 103.9 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) PLDc_N PF13396.6 CCC72071.1 - 0.5 10.3 3.7 0.56 10.2 0.0 2.2 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal Meiosis_expr PF15163.6 CCC72072.1 - 0.092 13.4 0.5 0.25 12.1 0.2 1.9 2 0 0 2 2 2 0 Meiosis-expressed Pmp3 PF01679.17 CCC72073.1 - 6.5e-16 58.3 7.8 8.2e-16 57.9 7.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator PsbW PF07123.12 CCC72073.1 - 0.073 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) Ac76 PF05814.11 CCC72073.1 - 0.16 12.0 3.0 0.17 11.9 0.2 2.0 1 1 1 2 2 2 0 Orf76 (Ac76) Pkinase PF00069.25 CCC72075.1 - 9e-69 231.8 0.1 3.5e-62 210.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 CCC72075.1 - 5.8e-48 163.4 0.1 5.5e-46 156.9 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.6 CCC72075.1 - 2.4e-34 117.6 0.4 5.5e-34 116.5 0.4 1.6 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.17 CCC72075.1 - 1.2e-09 38.1 0.0 4.4e-09 36.3 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 CCC72075.1 - 1.1e-06 28.9 0.1 3.4e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 CCC72075.1 - 5.8e-06 25.3 1.0 1.7e-05 23.8 1.0 1.9 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 CCC72075.1 - 1.9e-05 24.1 0.0 0.00027 20.4 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Methyltr_RsmB-F PF01189.17 CCC72075.1 - 0.015 15.0 0.1 0.027 14.1 0.1 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F SAM_4 PF18017.1 CCC72075.1 - 0.09 12.8 0.6 0.29 11.1 0.1 2.1 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Pex24p PF06398.11 CCC72076.1 - 2.2e-89 300.0 7.8 2.2e-89 300.0 7.8 1.4 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin RGCC PF15151.6 CCC72076.1 - 0.0026 18.0 0.5 0.0063 16.7 0.5 1.6 2 0 0 2 2 2 1 Response gene to complement 32 protein family zf-CCCH PF00642.24 CCC72077.1 - 3.6e-10 39.5 3.2 8e-10 38.4 3.2 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 CCC72077.1 - 6.5e-10 38.7 4.6 1.3e-09 37.8 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCC72077.1 - 6.2e-08 32.4 7.9 1.3e-07 31.3 7.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCC72077.1 - 3.3e-07 30.1 7.9 6.7e-07 29.2 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCC72077.1 - 1.3e-06 28.2 5.5 2.6e-06 27.2 5.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf_CCCH_4 PF18345.1 CCC72077.1 - 2.3e-06 27.5 5.7 4.3e-06 26.6 5.7 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-RING_2 PF13639.6 CCC72077.1 - 1e-05 25.7 7.4 2.2e-05 24.7 7.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 CCC72077.1 - 1.4e-05 24.9 8.2 2.9e-05 23.9 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC72077.1 - 1.6e-05 24.8 7.0 3.8e-05 23.6 7.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 CCC72077.1 - 0.00019 21.5 8.1 0.00045 20.3 8.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 CCC72077.1 - 0.00025 20.8 1.8 0.00052 19.8 1.8 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-RING_10 PF16685.5 CCC72077.1 - 0.00099 19.2 3.9 0.00099 19.2 3.9 1.9 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-rbx1 PF12678.7 CCC72077.1 - 0.045 14.0 3.6 0.097 13.0 3.6 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 CCC72077.1 - 0.1 12.5 3.2 0.2 11.6 3.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-CCCH_2 PF14608.6 CCC72077.1 - 0.11 13.0 2.2 0.25 11.9 2.2 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf-P11 PF03854.14 CCC72077.1 - 0.55 9.9 4.3 1.2 8.8 4.3 1.5 1 0 0 1 1 1 0 P-11 zinc finger Mus7 PF09462.10 CCC72078.1 - 7.1e-21 74.7 11.8 4.8e-15 55.5 3.1 2.4 2 0 0 2 2 2 2 Mus7/MMS22 family AIP3 PF03915.13 CCC72079.1 - 3.5e-138 461.1 16.2 6.6e-138 460.2 16.2 1.4 1 0 0 1 1 1 1 Actin interacting protein 3 DUF4298 PF14131.6 CCC72079.1 - 0.27 11.2 5.5 0.26 11.3 1.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) zf-CRD PF17979.1 CCC72079.1 - 1.3 9.2 7.9 1.5 8.9 1.9 2.7 3 0 0 3 3 3 0 Cysteine rich domain with multizinc binding regions DUF1640 PF07798.11 CCC72079.1 - 4.6 7.3 14.1 1.1 9.3 8.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Telomerase_RBD PF12009.8 CCC72080.1 - 1.3e-33 115.9 2.9 6e-33 113.8 2.9 2.2 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 CCC72080.1 - 9e-11 41.7 1.3 1e-05 25.2 0.1 2.7 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Vps39_2 PF10367.9 CCC72080.1 - 0.85 10.1 3.0 2.1 8.8 0.3 2.9 2 1 1 3 3 3 0 Vacuolar sorting protein 39 domain 2 dCMP_cyt_deam_1 PF00383.23 CCC72081.1 - 1.6e-10 40.8 0.0 3.3e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 CCC72081.1 - 2.2e-05 24.2 0.2 6.4e-05 22.7 0.2 1.8 1 0 0 1 1 1 1 MafB19-like deaminase Inv-AAD PF18785.1 CCC72081.1 - 0.09 12.6 0.2 1.6 8.6 0.1 2.7 3 0 0 3 3 3 0 Invertebrate-AID/APOBEC-deaminase SNF5 PF04855.12 CCC72082.1 - 4.4e-46 157.6 0.9 3.5e-24 85.9 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 NB-ARC PF00931.22 CCC72082.1 - 0.019 14.1 0.1 0.032 13.4 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain EF1_GNE PF00736.19 CCC72083.1 - 1.6e-32 111.6 1.1 2.7e-32 110.8 1.1 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.9 CCC72083.1 - 8.1e-14 51.8 5.8 8.1e-14 51.8 5.8 3.2 4 0 0 4 4 4 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_2 PF13410.6 CCC72083.1 - 0.012 15.6 0.1 0.11 12.5 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 CCC72083.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 CCC72083.1 - 0.14 12.4 1.5 0.51 10.6 1.5 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Vps8 PF12816.7 CCC72084.1 - 3.7e-55 186.5 12.5 1.1e-54 184.9 4.3 3.2 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 CCC72084.1 - 3.5e-05 23.7 7.7 0.0012 18.7 0.6 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-C3HC4 PF00097.25 CCC72084.1 - 0.0012 18.7 1.7 0.0029 17.4 1.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 CCC72084.1 - 0.05 13.9 0.5 0.13 12.6 0.5 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 CCC72084.1 - 0.092 12.5 0.6 0.24 11.2 0.6 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_2 PF13639.6 CCC72084.1 - 0.33 11.3 5.3 0.049 14.0 1.0 1.8 2 0 0 2 2 2 0 Ring finger domain zf-C3H2C3 PF17122.5 CCC72084.1 - 0.36 10.9 5.3 0.071 13.2 0.6 2.1 2 0 0 2 2 2 0 Zinc-finger zf-RING_5 PF14634.6 CCC72084.1 - 0.68 9.9 5.2 1.5 8.9 5.2 1.6 1 1 0 1 1 1 0 zinc-RING finger domain B-block_TFIIIC PF04182.12 CCC72085.1 - 2e-18 66.3 1.0 1.2e-17 63.8 0.3 2.6 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC AcetDehyd-dimer PF09290.11 CCC72085.1 - 0.056 13.6 0.5 1.1 9.5 0.2 2.7 2 0 0 2 2 2 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation DUF5314 PF17241.2 CCC72086.1 - 4.8e-09 36.2 0.1 1.6e-08 34.5 0.0 1.8 1 1 1 2 2 2 1 Family of unknown function (DUF5314) eIF3g PF12353.8 CCC72086.1 - 0.017 15.5 3.6 0.031 14.7 1.8 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G EMP24_GP25L PF01105.24 CCC72088.1 - 4.1e-54 183.3 0.9 4.8e-54 183.0 0.9 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SBDS PF01172.18 CCC72088.1 - 0.002 18.2 0.1 0.0036 17.3 0.1 1.5 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SdrD_B PF17210.3 CCC72088.1 - 0.037 14.2 0.1 0.11 12.7 0.0 1.7 1 1 1 2 2 2 0 SdrD B-like domain Tospo_nucleocap PF01533.16 CCC72088.1 - 0.044 13.2 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Tospovirus nucleocapsid protein Herpes_UL73 PF03554.13 CCC72088.1 - 0.082 12.9 0.4 0.21 11.6 0.4 1.6 1 0 0 1 1 1 0 UL73 viral envelope glycoprotein ATP-synt_8 PF00895.20 CCC72088.1 - 0.13 12.7 6.1 5 7.7 0.1 2.4 2 0 0 2 2 2 0 ATP synthase protein 8 WD40 PF00400.32 CCC72089.1 - 7.7e-13 48.7 3.7 1.8e-06 28.6 1.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC72089.1 - 4.6e-08 33.3 0.1 0.12 12.7 0.0 4.0 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCC72089.1 - 0.00025 21.0 0.6 0.043 13.7 0.0 3.3 2 2 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 CCC72089.1 - 0.0091 15.0 0.0 1.9 7.4 0.0 3.1 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 CCC72089.1 - 0.054 13.5 0.5 0.31 11.0 0.0 2.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 CCC72090.1 - 7.1e-19 67.8 10.7 0.00073 20.3 1.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 CCC72090.1 - 3.3e-13 49.7 4.1 2.3e-07 31.0 0.1 3.8 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 CCC72090.1 - 9.3e-06 25.6 0.2 0.0055 16.6 0.2 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Receptor_2B4 PF11465.8 CCC72090.1 - 0.049 13.8 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Rep_fac-A_C PF08646.10 CCC72091.1 - 3.4e-60 202.0 6.2 8.1e-57 191.1 3.3 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 CCC72091.1 - 1.3e-35 121.2 0.1 8.4e-30 102.6 0.1 3.9 4 0 0 4 4 4 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 CCC72091.1 - 1.6e-16 60.0 0.3 4.9e-08 32.8 0.0 4.5 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 CCC72091.1 - 3.5e-09 36.7 0.0 1.2e-06 28.5 0.0 3.4 3 1 0 3 3 3 1 Cell division control protein 24, OB domain 3 Rep-A_N PF04057.12 CCC72091.1 - 1.3e-06 28.3 0.1 3.7e-06 26.9 0.1 1.9 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain POT1 PF02765.17 CCC72091.1 - 0.0045 16.8 0.6 3.2 7.6 0.1 3.2 3 0 0 3 3 3 2 Telomeric single stranded DNA binding POT1/CDC13 BRCA-2_OB1 PF09103.10 CCC72091.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 DUF3127 PF11325.8 CCC72091.1 - 0.021 15.1 0.2 3.3 8.0 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF3127) DUF223 PF02721.14 CCC72091.1 - 0.028 14.7 0.7 0.11 12.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF223 tRNA_int_endo PF01974.17 CCC72092.1 - 2.1e-12 46.9 0.0 4.4e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain TAL_FSA PF00923.19 CCC72093.1 - 2.4e-99 332.3 0.4 2.8e-99 332.1 0.4 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase IlvN PF07991.12 CCC72094.1 - 4.9e-46 156.3 0.0 6.9e-46 155.8 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 CCC72094.1 - 9.7e-40 136.2 0.1 2.2e-39 135.0 0.0 1.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.15 CCC72094.1 - 0.15 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF2718 PF10918.8 CCC72095.1 - 0.094 13.2 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2718) eIF2A PF08662.11 CCC72096.1 - 1.3e-75 253.5 0.2 8.8e-75 250.8 0.1 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 CCC72096.1 - 0.00012 22.8 1.4 4.3 8.4 0.0 4.9 4 2 2 6 6 6 2 WD domain, G-beta repeat HPS3_N PF14761.6 CCC72096.1 - 0.0043 16.6 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3 AA_permease_2 PF13520.6 CCC72097.1 - 9.6e-84 281.7 48.7 1.2e-83 281.3 48.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 CCC72097.1 - 8.5e-20 70.8 45.9 1.1e-19 70.4 45.9 1.1 1 0 0 1 1 1 1 Amino acid permease EPTP PF03736.17 CCC72097.1 - 0.054 13.5 0.8 3.1 7.9 0.1 3.4 2 1 1 3 3 3 0 EPTP domain MotA_ExbB PF01618.16 CCC72097.1 - 4.7 7.0 7.1 1.6 8.4 0.6 2.9 3 0 0 3 3 3 0 MotA/TolQ/ExbB proton channel family BAH PF01426.18 CCC72098.1 - 2.4e-25 88.8 0.1 4.3e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 BAH domain Bromodomain PF00439.25 CCC72098.1 - 2.8e-21 75.4 6.9 4e-14 52.5 0.2 2.6 2 0 0 2 2 2 2 Bromodomain Lyase_1 PF00206.20 CCC72099.1 - 4.8e-24 85.3 0.0 8e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.9 CCC72099.1 - 4.9e-17 62.2 0.1 3e-16 59.7 0.0 2.4 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus DUF1331 PF07048.11 CCC72099.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1331) VPS38 PF17649.1 CCC72100.1 - 1.8e-161 537.8 19.7 2e-161 537.6 19.7 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 38 DUF2408 PF10303.9 CCC72100.1 - 0.29 11.7 4.5 0.43 11.2 2.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2408) HIP1_clath_bdg PF16515.5 CCC72100.1 - 0.51 11.0 3.3 1.5 9.5 3.3 1.7 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Metallophos PF00149.28 CCC72101.1 - 6.2e-18 66.0 0.6 1.1e-17 65.2 0.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase CENP-F_leu_zip PF10473.9 CCC72102.1 - 0.72 9.9 56.7 0.049 13.7 9.2 4.1 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.11 CCC72102.1 - 2.9 8.2 16.5 5.5 7.3 0.9 3.8 2 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) PIN_4 PF13638.6 CCC72103.1 - 2e-05 24.9 0.1 3.8e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 PIN domain HTH_56 PF18662.1 CCC72103.1 - 0.088 12.9 0.8 0.27 11.3 0.8 1.9 1 1 0 1 1 1 0 Cch helix turn helix domain Thioredoxin_9 PF14595.6 CCC72104.1 - 1.5e-05 24.8 0.0 1.6e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 CCC72104.1 - 4.8e-05 23.5 0.0 7.4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin CaATP_NAI PF12515.8 CCC72104.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain ArsD PF06953.11 CCC72104.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 Arsenical resistance operon trans-acting repressor ArsD DUF953 PF06110.11 CCC72104.1 - 0.18 11.4 0.9 0.26 10.9 0.9 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) HSP70 PF00012.20 CCC72105.1 - 2e-213 710.0 13.1 2.3e-213 709.7 13.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 CCC72105.1 - 3.2e-19 68.9 2.8 1.4e-16 60.3 1.3 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 CCC72105.1 - 0.0022 17.8 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Raco_middle PF17651.1 CCC72105.1 - 0.086 12.5 0.3 1.2 8.8 0.0 2.7 2 0 0 2 2 2 0 RACo middle region RuvX PF03652.15 CCC72105.1 - 0.22 11.9 2.1 2.1 8.8 0.0 3.0 4 0 0 4 4 4 0 Holliday junction resolvase GlutR_dimer PF00745.20 CCC72105.1 - 2.2 8.8 8.0 0.31 11.5 1.5 2.9 3 2 1 4 4 4 0 Glutamyl-tRNAGlu reductase, dimerisation domain Terminase_2 PF03592.16 CCC72105.1 - 5.7 7.4 10.3 1.3 9.5 5.7 2.2 2 0 0 2 2 2 0 Terminase small subunit P21-Arc PF04062.14 CCC72106.1 - 5.7e-75 251.1 0.0 6.4e-75 251.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit ELO PF01151.18 CCC72107.1 - 2.6e-57 194.2 31.5 3.4e-57 193.8 31.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family zf-BED PF02892.15 CCC72108.1 - 6.9e-08 32.4 0.9 1.5e-07 31.4 0.9 1.6 1 0 0 1 1 1 1 BED zinc finger CDC45 PF02724.14 CCC72108.1 - 2.1 6.5 10.6 3.6 5.8 10.6 1.4 1 0 0 1 1 1 0 CDC45-like protein Cut12 PF11500.8 CCC72108.1 - 5.7 6.9 0.0 5.7 6.9 0.0 3.1 3 0 0 3 3 3 0 Spindle pole body formation-associated protein zf-C2H2_jaz PF12171.8 CCC72109.1 - 8.9e-06 25.9 5.0 0.046 14.0 0.0 3.8 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 CCC72109.1 - 1e-05 26.0 24.4 0.0006 20.4 0.7 5.1 5 0 0 5 5 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 CCC72109.1 - 0.00028 21.2 1.5 0.00028 21.2 1.5 5.1 5 1 0 5 5 4 1 Zinc finger, C2H2 type zf-SNAP50_C PF12251.8 CCC72109.1 - 0.00041 20.1 3.1 0.014 15.1 0.3 2.3 2 0 0 2 2 2 1 snRNA-activating protein of 50kDa MW C terminal Zn-C2H2_12 PF18112.1 CCC72109.1 - 0.0057 17.1 0.3 2.8 8.5 0.1 3.1 2 0 0 2 2 2 1 Autophagy receptor zinc finger-C2H2 domain zf-Di19 PF05605.12 CCC72109.1 - 0.0086 16.4 7.9 0.022 15.1 1.9 3.6 3 1 1 4 4 4 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.6 CCC72109.1 - 0.0086 16.1 0.3 0.0086 16.1 0.3 3.9 3 1 0 3 3 3 1 C2H2-type zinc finger zf-H2C2_2 PF13465.6 CCC72109.1 - 0.021 15.2 1.2 0.021 15.2 1.2 4.8 4 1 1 5 5 5 0 Zinc-finger double domain Rad50_zn_hook PF04423.14 CCC72109.1 - 0.038 13.8 2.4 0.25 11.2 0.2 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4_3 PF13920.6 CCC72109.1 - 0.17 11.8 5.7 6.8 6.6 0.2 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C2HC_2 PF13913.6 CCC72109.1 - 0.66 9.9 10.7 4.2 7.4 0.1 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-RING_2 PF13639.6 CCC72109.1 - 0.73 10.2 6.2 34 4.9 0.0 3.4 3 0 0 3 3 3 0 Ring finger domain zinc_ribbon_9 PF14369.6 CCC72109.1 - 1.1 9.6 4.0 6.8 7.0 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon DUF2256 PF10013.9 CCC72109.1 - 2.7 8.2 6.8 52 4.1 0.1 3.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) GAGA PF09237.11 CCC72109.1 - 6.1 6.7 5.8 2.4 8.1 0.5 2.8 3 0 0 3 3 3 0 GAGA factor KRE9 PF05390.11 CCC72110.1 - 5.6e-23 81.6 3.2 1e-22 80.8 3.2 1.4 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.9 CCC72110.1 - 1.3e-07 32.2 0.0 2.3e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PSY3 PF16836.5 CCC72111.1 - 4.2e-77 258.5 3.4 4.8e-77 258.4 3.4 1.0 1 0 0 1 1 1 1 Shu complex component Psy3, DNA-binding description FBPase PF00316.20 CCC72112.1 - 4.5e-72 241.5 0.6 7.6e-72 240.8 0.6 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 CCC72112.1 - 0.17 11.3 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family SecY PF00344.20 CCC72113.1 - 1.6e-62 211.5 13.6 2.2e-62 211.1 13.6 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 CCC72113.1 - 9.9e-18 63.7 0.2 5.5e-17 61.3 0.2 2.4 1 0 0 1 1 1 1 Plug domain of Sec61p Cation_ATPase_C PF00689.21 CCC72113.1 - 0.19 11.4 12.3 2.1 8.0 0.2 3.2 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus Claudin_3 PF06653.11 CCC72113.1 - 0.33 10.9 0.1 0.33 10.9 0.1 3.0 3 1 0 3 3 3 0 Tight junction protein, Claudin-like SdpI PF13630.6 CCC72113.1 - 3.3 7.9 7.8 0.18 12.0 0.4 2.7 3 0 0 3 3 3 0 SdpI/YhfL protein family NTP_transferase PF00483.23 CCC72114.1 - 2.4e-52 178.0 0.0 3.1e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 CCC72114.1 - 8.3e-14 50.7 12.9 2.2e-07 30.3 2.1 4.1 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 CCC72114.1 - 1.1e-10 42.0 0.0 1.4e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 CCC72114.1 - 0.00018 21.2 3.6 0.004 16.9 1.2 3.1 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 CCC72114.1 - 0.049 12.6 0.0 0.24 10.3 0.1 1.9 2 0 0 2 2 2 0 L-fucokinase IspD PF01128.19 CCC72114.1 - 0.05 13.3 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 CCC72114.1 - 0.15 11.9 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase CRAL_TRIO PF00650.20 CCC72115.1 - 1.8e-33 115.5 0.1 4.2e-33 114.3 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 CCC72115.1 - 3.6e-11 43.1 0.0 9.4e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 CCC72115.1 - 1.1e-06 28.8 0.3 1.3e-05 25.4 0.1 2.3 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain tRNA-synt_1 PF00133.22 CCC72117.1 - 6.5e-48 163.4 0.1 4.3e-18 64.9 0.4 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 CCC72117.1 - 6.3e-37 126.9 0.0 1.2e-36 125.9 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 CCC72117.1 - 6.7e-30 104.1 0.1 6.2e-21 74.6 0.0 5.1 4 1 1 5 5 5 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 CCC72117.1 - 5.1e-05 23.3 0.6 0.00011 22.3 0.6 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.19 CCC72117.1 - 9.1e-05 21.6 0.1 0.042 12.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (R) tRNA-synt_1e PF01406.19 CCC72117.1 - 0.00093 18.6 0.0 0.017 14.5 0.0 2.7 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain DNA_ligase_ZBD PF03119.16 CCC72117.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain zf-ribbon_3 PF13248.6 CCC72117.1 - 0.8 9.2 2.4 9.6 5.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain SMC_N PF02463.19 CCC72118.1 - 1.2e-18 67.4 30.7 2.1e-13 50.2 0.4 3.6 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 CCC72118.1 - 3.4e-16 60.3 22.8 3.4e-16 60.3 22.8 5.7 3 2 2 5 5 5 1 AAA domain AAA_15 PF13175.6 CCC72118.1 - 3e-14 53.5 21.3 3e-14 53.5 21.3 4.0 2 2 1 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 CCC72118.1 - 5.3e-08 33.0 11.4 0.00037 20.4 0.2 3.4 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 CCC72118.1 - 0.00027 20.6 0.0 0.0008 19.1 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain HsbA PF12296.8 CCC72118.1 - 0.023 15.1 3.0 3.5 8.1 0.1 4.0 4 0 0 4 4 4 0 Hydrophobic surface binding protein A ABC_tran PF00005.27 CCC72118.1 - 0.03 14.8 0.1 0.03 14.8 0.1 5.8 3 2 0 3 3 3 0 ABC transporter AAA_27 PF13514.6 CCC72118.1 - 0.08 12.5 0.0 0.08 12.5 0.0 4.3 3 2 0 4 4 4 0 AAA domain Fez1 PF06818.15 CCC72118.1 - 4.5 7.7 81.6 0.16 12.4 23.1 6.3 3 2 5 8 8 8 0 Fez1 Hemerythrin PF01814.23 CCC72118.1 - 4.6 7.9 7.0 3.8 8.1 4.1 2.4 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain IKI3 PF04762.12 CCC72119.1 - 0 1152.9 7.5 0 1152.9 7.5 1.3 2 0 0 2 2 2 1 IKI3 family ANAPC4_WD40 PF12894.7 CCC72119.1 - 0.00024 21.3 3.3 0.026 14.8 1.4 3.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Tom37 PF10568.9 CCC72119.1 - 0.03 14.6 0.3 0.15 12.4 0.4 2.2 2 0 0 2 2 2 0 Outer mitochondrial membrane transport complex protein MIT PF04212.18 CCC72119.1 - 0.068 13.2 4.9 2 8.6 0.3 3.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain IF-2B PF01008.17 CCC72119.1 - 0.092 11.9 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Initiation factor 2 subunit family SWC7 PF17330.2 CCC72120.1 - 2.4e-38 130.1 2.4 2.9e-38 129.9 2.4 1.1 1 0 0 1 1 1 1 SWR1 chromatin-remodelling complex, sub-unit Swc7 FliL PF03748.14 CCC72120.1 - 0.067 13.8 1.2 0.11 13.1 0.2 1.7 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL Stap_Strp_toxin PF01123.20 CCC72120.1 - 0.08 13.8 0.1 0.19 12.6 0.0 1.7 2 0 0 2 2 2 0 Staphylococcal/Streptococcal toxin, OB-fold domain Vac14_Fig4_bd PF11916.8 CCC72121.1 - 3e-67 225.8 10.4 3.4e-67 225.6 9.1 1.8 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 CCC72121.1 - 1.2e-46 157.2 0.5 2.7e-38 130.4 0.1 4.4 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 CCC72121.1 - 8e-10 39.0 0.1 0.32 11.5 0.1 6.7 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.22 CCC72121.1 - 3.9e-08 32.9 6.0 0.0013 18.8 0.0 6.2 7 0 0 7 7 7 2 HEAT repeat CLASP_N PF12348.8 CCC72121.1 - 1.9e-06 27.6 1.8 0.034 13.7 0.6 4.4 4 0 0 4 4 4 1 CLASP N terminal HEAT_2 PF13646.6 CCC72121.1 - 4.7e-05 23.7 0.1 2.3 8.6 0.0 5.1 4 2 1 5 5 5 1 HEAT repeats Arm PF00514.23 CCC72121.1 - 8e-05 22.5 4.1 2.6 8.2 0.3 4.9 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat ParcG PF10274.9 CCC72121.1 - 0.0034 17.5 8.7 0.012 15.7 0.3 3.7 2 1 0 4 4 4 1 Parkin co-regulated protein RTP1_C1 PF10363.9 CCC72121.1 - 0.1 12.8 6.8 0.61 10.3 0.6 4.0 2 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 RasGEF_N_2 PF14663.6 CCC72121.1 - 0.44 11.0 5.0 0.95 9.9 0.3 3.7 3 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain zf-C2H2_2 PF12756.7 CCC72122.1 - 4.4e-33 113.6 4.2 3e-30 104.5 2.8 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 CCC72122.1 - 5.7 7.6 9.7 1.1 9.9 1.0 3.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 CCC72122.1 - 8.2 6.8 12.2 1.4 9.3 0.9 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RIBIOP_C PF04950.12 CCC72124.1 - 1.7e-104 349.3 0.0 3.2e-104 348.4 0.0 1.5 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 CCC72124.1 - 2.1e-22 79.0 0.0 4.9e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain NAD_binding_10 PF13460.6 CCC72124.1 - 0.022 14.7 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Ribosomal_S14 PF00253.21 CCC72125.1 - 4.1e-15 55.3 3.0 4.6e-15 55.1 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.12 CCC72125.1 - 0.038 14.3 2.4 1 9.7 0.3 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Peptidase_M16_M PF16187.5 CCC72126.1 - 1.1e-87 293.9 5.2 1.1e-87 293.9 5.2 1.6 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 CCC72126.1 - 8e-38 129.8 0.0 5.1e-37 127.1 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 CCC72126.1 - 1e-28 100.6 2.6 4.1e-18 66.1 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF575 PF04746.12 CCC72127.1 - 0.053 13.8 0.0 0.056 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF575) Activator_LAG-3 PF11498.8 CCC72127.1 - 1 8.3 10.9 1 8.2 10.9 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CFEM PF05730.11 CCC72128.1 - 3.5e-09 36.6 12.1 9.5e-09 35.2 12.1 1.8 1 0 0 1 1 1 1 CFEM domain GCOM2 PF15328.6 CCC72128.1 - 6.4 7.1 12.7 9.3 6.6 12.7 1.3 1 0 0 1 1 1 0 Putative GRINL1B complex locus protein 2 RIFIN PF02009.16 CCC72128.1 - 6.8 6.5 6.3 8.2 6.2 6.3 1.3 1 0 0 1 1 1 0 Rifin Hid1 PF12722.7 CCC72128.1 - 7.5 4.5 14.6 8.4 4.4 14.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Arrestin_N PF00339.29 CCC72129.1 - 0.00027 21.0 0.0 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain ATP-synt_10 PF05176.14 CCC72130.1 - 4.8e-75 252.1 0.1 5.7e-75 251.9 0.1 1.0 1 0 0 1 1 1 1 ATP10 protein TcdA_TcdB_pore PF12920.7 CCC72130.1 - 0.11 10.7 0.2 0.15 10.3 0.2 1.1 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain zf-RING_5 PF14634.6 CCC72131.1 - 8.7e-07 28.8 5.9 2.1e-06 27.6 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 CCC72131.1 - 0.016 15.1 6.6 0.042 13.7 6.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 CCC72131.1 - 0.14 12.1 4.3 0.36 10.7 4.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Guanylin PF02058.15 CCC72131.1 - 0.24 11.9 0.2 0.24 11.9 0.2 2.6 3 0 0 3 3 3 0 Guanylin precursor zf-RING_6 PF14835.6 CCC72131.1 - 0.34 10.8 3.4 0.76 9.7 3.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_2 PF13923.6 CCC72131.1 - 0.34 10.8 6.7 0.72 9.8 6.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 CCC72131.1 - 5 7.2 8.0 2.1 8.4 2.5 2.5 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.6 CCC72131.1 - 6.8 7.1 13.1 0.16 12.3 6.6 1.7 2 0 0 2 2 2 0 Ring finger domain COX7C PF02935.16 CCC72132.1 - 9.6e-23 80.2 1.1 1.1e-22 80.0 1.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc LapA_dom PF06305.11 CCC72132.1 - 0.12 12.2 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain Sec1 PF00995.23 CCC72133.1 - 9.8e-88 295.8 10.5 1.2e-87 295.5 10.5 1.0 1 0 0 1 1 1 1 Sec1 family UNC45-central PF11701.8 CCC72133.1 - 0.08 12.9 0.1 0.97 9.4 0.1 2.4 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central AAA PF00004.29 CCC72134.1 - 1.7e-91 303.5 0.0 3.6e-44 150.4 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 CCC72134.1 - 1.4e-24 85.6 0.5 1.2e-11 44.2 0.4 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 CCC72134.1 - 6.3e-13 48.8 0.0 3.9e-05 23.5 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 CCC72134.1 - 3.1e-12 47.2 0.1 2.2e-06 28.2 0.0 3.7 2 2 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 CCC72134.1 - 2e-11 44.0 0.1 8.9e-05 22.5 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 CCC72134.1 - 1.6e-09 38.1 0.0 0.00019 21.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 CCC72134.1 - 4e-09 36.9 1.5 0.00023 21.5 0.1 4.6 2 2 1 3 3 3 1 AAA domain AAA_33 PF13671.6 CCC72134.1 - 8.7e-08 32.4 0.0 0.00058 20.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 CCC72134.1 - 1.8e-07 31.3 0.0 0.00084 19.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 CCC72134.1 - 1.3e-06 27.9 0.0 0.0056 15.9 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain Bac_DnaA PF00308.18 CCC72134.1 - 9.7e-06 25.6 0.0 0.0019 18.1 0.0 2.6 2 1 0 2 2 2 1 Bacterial dnaA protein Rad17 PF03215.15 CCC72134.1 - 1e-05 25.6 0.0 0.015 15.2 0.0 3.1 2 1 0 2 2 2 1 Rad17 P-loop domain RNA_helicase PF00910.22 CCC72134.1 - 1.4e-05 25.4 0.0 0.19 12.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.21 CCC72134.1 - 2.9e-05 23.6 0.2 0.094 12.1 0.1 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_N PF02359.18 CCC72134.1 - 6.8e-05 23.0 0.8 0.00017 21.7 0.2 2.0 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain TsaE PF02367.17 CCC72134.1 - 9.7e-05 22.4 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 CCC72134.1 - 0.00019 21.7 0.0 0.64 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 CCC72134.1 - 0.00027 20.6 5.0 2.4 7.7 0.0 4.1 3 1 1 4 4 4 2 AAA domain AAA_11 PF13086.6 CCC72134.1 - 0.00033 20.5 0.0 0.06 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 CCC72134.1 - 0.00048 19.7 0.1 0.93 9.0 0.0 2.6 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_3 PF07726.11 CCC72134.1 - 0.0017 18.3 0.0 1.8 8.5 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 CCC72134.1 - 0.0021 17.8 0.0 2 8.1 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.12 CCC72134.1 - 0.0025 17.8 0.3 0.064 13.2 0.0 3.0 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.6 CCC72134.1 - 0.0037 17.0 0.0 0.035 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.6 CCC72134.1 - 0.0039 17.3 0.0 0.35 11.0 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 CCC72134.1 - 0.0059 16.5 0.0 34 4.2 0.0 3.6 2 2 1 3 3 3 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 CCC72134.1 - 0.0065 16.2 0.0 0.51 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 CCC72134.1 - 0.0082 16.7 0.0 1.1 9.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 CCC72134.1 - 0.0085 15.9 0.0 0.075 12.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.6 CCC72134.1 - 0.013 15.9 0.6 0.39 11.1 0.1 3.0 3 1 1 4 4 2 0 AAA domain ABC_tran PF00005.27 CCC72134.1 - 0.015 15.8 0.0 0.36 11.4 0.0 2.7 2 1 0 2 2 2 0 ABC transporter DUF815 PF05673.13 CCC72134.1 - 0.023 13.9 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Vps4_C PF09336.10 CCC72134.1 - 0.026 14.5 0.1 7.3 6.7 0.0 3.5 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.26 CCC72134.1 - 0.036 13.8 0.0 15 5.3 0.0 3.6 2 2 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 CCC72134.1 - 0.055 12.7 0.1 6.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AFG1_ATPase PF03969.16 CCC72134.1 - 0.1 11.5 0.0 0.35 9.7 0.0 1.9 3 0 0 3 3 2 0 AFG1-like ATPase ATPase PF06745.13 CCC72134.1 - 0.19 11.0 3.2 18 4.6 0.1 3.5 3 1 1 4 4 3 0 KaiC DSHCT PF08148.12 CCC72135.1 - 5.7e-47 159.4 1.5 8.6e-47 158.8 0.2 2.1 3 0 0 3 3 3 1 DSHCT (NUC185) domain Ski2_N PF17911.1 CCC72135.1 - 3.4e-38 130.5 0.1 1.1e-37 128.8 0.1 1.9 1 0 0 1 1 1 1 Ski2 N-terminal region DEAD PF00270.29 CCC72135.1 - 6.8e-21 74.8 0.1 1.8e-20 73.5 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.6 CCC72135.1 - 8.3e-15 55.4 3.7 2.1e-14 54.1 3.7 1.8 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.31 CCC72135.1 - 3.8e-07 30.4 0.0 2.3e-06 27.9 0.0 2.5 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 CCC72135.1 - 4.3e-07 30.1 0.0 1.6e-06 28.2 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3287 PF11690.8 CCC72135.1 - 0.31 10.7 2.0 3 7.6 0.0 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF3287) Bromodomain PF00439.25 CCC72136.1 - 1.9e-38 130.4 2.2 2.7e-18 65.8 0.2 2.6 2 0 0 2 2 2 2 Bromodomain BET PF17035.5 CCC72136.1 - 2e-14 53.5 0.4 6.2e-14 51.9 0.0 2.2 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation DUF4094 PF13334.6 CCC72136.1 - 0.12 12.8 0.2 0.82 10.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) BRCC36_C PF18110.1 CCC72136.1 - 0.97 9.6 3.2 0.9 9.7 1.0 2.1 2 0 0 2 2 2 0 BRCC36 C-terminal helical domain YabA PF06156.13 CCC72136.1 - 1.9 9.1 4.5 8.2 7.1 4.5 2.0 1 0 0 1 1 1 0 Initiation control protein YabA Dus PF01207.17 CCC72137.1 - 1.8e-44 152.1 0.0 9.7e-42 143.1 0.0 2.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 CCC72137.1 - 3.8e-06 26.6 10.3 7.1e-05 22.5 1.5 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 CCC72137.1 - 0.47 10.6 7.2 0.071 13.2 1.6 2.5 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH PF00642.24 CCC72137.1 - 0.62 10.0 8.6 0.1 12.5 0.6 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 CCC72137.1 - 1.6 9.5 6.3 12 6.7 0.6 2.8 1 1 1 2 2 2 0 Torus domain Lustrin_cystein PF14625.6 CCC72137.1 - 2.1 8.8 4.0 3.9e+02 1.5 4.4 3.5 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain zf-CCCH_2 PF14608.6 CCC72137.1 - 2.3 8.8 6.1 0.97 10.0 0.4 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-C2H2 PF00096.26 CCC72138.1 - 1.2e-05 25.5 17.3 0.013 15.9 0.8 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 CCC72138.1 - 0.00011 22.7 17.9 0.032 15.1 0.6 3.9 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_aberr PF17017.5 CCC72138.1 - 0.0024 18.0 8.4 0.11 12.6 0.1 2.9 3 0 0 3 3 3 2 Aberrant zinc-finger zf-H2C2_2 PF13465.6 CCC72138.1 - 0.0071 16.7 14.8 0.061 13.8 0.3 3.8 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.8 CCC72138.1 - 0.009 16.3 1.1 1.5 9.2 0.1 3.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2HE PF16278.5 CCC72138.1 - 0.31 11.5 3.2 0.59 10.6 0.2 2.6 1 1 1 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2_3rep PF18868.1 CCC72138.1 - 0.41 11.3 7.9 0.38 11.4 0.5 2.9 2 1 0 2 2 2 0 Zinc finger C2H2-type, 3 repeats Seipin PF06775.14 CCC72139.1 - 0.016 15.3 0.0 0.59 10.2 0.0 2.7 2 1 1 3 3 3 0 Putative adipose-regulatory protein (Seipin) SfLAP PF11139.8 CCC72139.1 - 0.13 11.7 1.9 0.22 11.0 1.9 1.3 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein DUF5408 PF17402.2 CCC72139.1 - 0.47 10.4 1.7 0.88 9.5 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5408) DUF5379 PF17350.2 CCC72139.1 - 0.96 9.8 5.5 10 6.5 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5379) Dus PF01207.17 CCC72140.1 - 2.7e-74 250.1 0.0 3.3e-74 249.8 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Flavodoxin_2 PF02525.17 CCC72141.1 - 8.7e-55 185.5 0.0 1e-54 185.3 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.15 CCC72141.1 - 9.7e-13 48.1 0.0 2.1e-12 47.1 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.7 CCC72141.1 - 0.11 12.1 0.1 0.2 11.3 0.1 1.4 1 0 0 1 1 1 0 Flavodoxin DUF4050 PF13259.6 CCC72142.1 - 9.3e-10 39.1 6.7 5.8e-08 33.3 6.7 2.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) Utp21 PF04192.12 CCC72144.1 - 5.5e-79 264.9 2.2 8.2e-79 264.4 2.2 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain ANAPC4_WD40 PF12894.7 CCC72144.1 - 7.9e-17 61.4 0.0 0.0001 22.5 0.0 6.2 4 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 CCC72144.1 - 2.7e-15 56.5 16.5 6e-08 33.2 0.6 7.6 8 0 0 8 8 8 2 WD domain, G-beta repeat eIF2A PF08662.11 CCC72144.1 - 2.4e-05 24.3 0.2 0.042 13.7 0.0 3.5 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.15 CCC72144.1 - 0.0015 17.9 0.3 0.011 15.1 0.1 2.6 4 0 0 4 4 4 1 CPSF A subunit region Cytochrom_D1 PF02239.16 CCC72144.1 - 0.0062 15.1 0.0 0.021 13.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.6 CCC72144.1 - 0.008 15.8 0.0 0.071 12.7 0.0 2.4 2 0 0 2 2 2 1 PQQ-like domain Nucleoporin_N PF08801.11 CCC72144.1 - 0.065 12.0 0.7 1.5 7.5 0.0 2.9 3 0 0 3 3 3 0 Nup133 N terminal like His_Phos_2 PF00328.22 CCC72145.1 - 2.6e-139 464.9 0.4 3.7e-139 464.3 0.4 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 CCC72145.1 - 5.3e-39 132.3 0.1 1.4e-38 131.0 0.1 1.7 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 CCC72145.1 - 7e-08 32.3 0.0 3.7e-07 29.9 0.0 2.1 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Ctr PF04145.15 CCC72146.1 - 1.6e-35 122.9 1.3 2.1e-35 122.5 1.3 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Glyoxalase_2 PF12681.7 CCC72146.1 - 0.0052 16.7 0.2 0.012 15.5 0.1 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain GP3 PF03076.14 CCC72146.1 - 0.11 12.6 0.6 0.18 11.9 0.6 1.3 1 0 0 1 1 1 0 Equine arteritis virus GP3 DUF1729 PF08354.10 CCC72147.1 - 9.4e-157 521.4 0.0 1.4e-156 520.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) Acyl_transf_1 PF00698.21 CCC72147.1 - 5.5e-104 348.1 0.0 2.9e-103 345.7 0.0 2.2 3 0 0 3 3 3 1 Acyl transferase domain FAS_meander PF17951.1 CCC72147.1 - 1e-46 158.4 0.1 2.2e-46 157.3 0.1 1.6 1 0 0 1 1 1 1 Fatty acid synthase meander beta sheet domain SAT PF16073.5 CCC72147.1 - 1.6e-37 129.5 0.0 3.6e-37 128.4 0.0 1.6 1 0 0 1 1 1 1 Starter unit:ACP transacylase in aflatoxin biosynthesis MaoC_dehydratas PF01575.19 CCC72147.1 - 2.2e-35 120.9 0.0 4.6e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain FAS_N PF17828.1 CCC72147.1 - 5.7e-34 116.9 0.0 1.4e-33 115.7 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta MaoC_dehydrat_N PF13452.6 CCC72147.1 - 9.6e-14 51.7 0.0 2.3e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase SUR7 PF06687.12 CCC72148.1 - 3.1e-12 46.6 21.5 1.2e-10 41.4 21.5 2.9 1 1 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.8 CCC72148.1 - 0.00098 19.1 12.0 0.0026 17.7 5.7 3.1 2 0 0 2 2 2 2 Ca2+ regulator and membrane fusion protein Fig1 DUF2101 PF09874.9 CCC72148.1 - 9.7 5.8 11.6 0.5 10.0 0.4 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) SUR7 PF06687.12 CCC72149.1 - 1.4e-41 142.5 15.7 1.7e-41 142.2 15.7 1.0 1 0 0 1 1 1 1 SUR7/PalI family DUF5090 PF17009.5 CCC72149.1 - 6.5 6.7 11.8 0.44 10.5 6.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5090) Vps36_ESCRT-II PF11605.8 CCC72150.1 - 7.8e-33 112.5 0.1 2.5e-32 110.9 0.1 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 EAP30 PF04157.16 CCC72150.1 - 1.5e-22 80.1 0.2 2.7e-22 79.2 0.2 1.4 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36-NZF-N PF16988.5 CCC72150.1 - 4.4e-15 54.8 5.1 4.4e-15 54.8 5.1 3.1 2 1 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain bPH_3 PF14470.6 CCC72150.1 - 0.00016 22.0 0.6 0.00094 19.5 0.2 2.5 2 0 0 2 2 2 1 Bacterial PH domain GRAM PF02893.20 CCC72150.1 - 0.0023 17.8 0.1 0.028 14.3 0.0 2.4 2 0 0 2 2 2 1 GRAM domain PH_TFIIH PF08567.11 CCC72150.1 - 0.0024 18.2 1.0 0.009 16.3 0.4 2.3 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain DZR PF12773.7 CCC72150.1 - 0.0094 16.0 6.0 0.018 15.0 1.3 2.4 2 0 0 2 2 2 1 Double zinc ribbon SET PF00856.28 CCC72150.1 - 0.01 16.3 0.4 0.01 16.3 0.4 2.2 2 1 0 2 2 2 1 SET domain zf-Sec23_Sec24 PF04810.15 CCC72150.1 - 0.022 14.8 11.8 0.19 11.8 0.0 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger ToxN_toxin PF13958.6 CCC72150.1 - 0.023 14.9 2.6 0.023 14.9 2.6 2.6 3 0 0 3 3 3 0 Toxin ToxN, type III toxin-antitoxin system zf-RanBP PF00641.18 CCC72150.1 - 0.025 13.9 10.6 0.23 10.8 1.5 3.1 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others FYDLN_acid PF09538.10 CCC72150.1 - 0.042 14.5 0.8 0.042 14.5 0.8 2.7 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) DUF2719 PF10891.8 CCC72150.1 - 0.096 12.6 0.3 0.34 10.8 0.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) CDC73_C PF05179.14 CCC72151.1 - 1.6e-55 187.1 6.1 1.6e-55 187.1 6.1 1.5 2 0 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family, C-terminal Helicase_C PF00271.31 CCC72152.1 - 6.1e-14 52.3 0.8 1.5e-13 51.1 0.2 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 CCC72152.1 - 6.2e-14 52.1 0.0 1.6e-13 50.8 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.22 CCC72152.1 - 8.4e-14 51.9 3.1 4e-13 49.7 3.1 2.3 1 1 0 1 1 1 1 RWD domain DEAD PF00270.29 CCC72152.1 - 7e-10 38.9 0.4 1.8e-09 37.6 0.4 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase HA2 PF04408.23 CCC72152.1 - 2.4e-08 34.2 0.0 2.4e-08 34.2 0.0 2.8 3 0 0 3 3 2 1 Helicase associated domain (HA2) PhoH PF02562.16 CCC72152.1 - 6.6e-05 22.4 0.2 0.0027 17.2 0.1 2.9 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.6 CCC72152.1 - 0.00069 19.9 0.0 0.0027 18.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 CCC72152.1 - 0.00085 19.7 0.1 0.0022 18.4 0.1 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 CCC72152.1 - 0.0041 16.2 0.0 0.008 15.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 CCC72152.1 - 0.0042 16.8 0.0 0.0095 15.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 CCC72152.1 - 0.0083 16.1 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain FtsK_SpoIIIE PF01580.18 CCC72152.1 - 0.0098 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_25 PF13481.6 CCC72152.1 - 0.014 14.9 0.0 0.037 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 CCC72152.1 - 0.015 15.3 2.6 0.016 15.2 0.1 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 CCC72152.1 - 0.015 14.8 0.0 0.039 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 CCC72152.1 - 0.023 14.0 0.1 0.09 12.1 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.6 CCC72152.1 - 0.03 14.8 0.1 0.03 14.8 0.1 4.4 4 2 1 5 5 5 0 AAA domain DND1_DSRM PF14709.7 CCC72152.1 - 0.062 13.6 0.0 0.22 11.8 0.0 2.0 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 ABC_tran PF00005.27 CCC72152.1 - 0.12 12.9 0.1 1.3 9.5 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.26 CCC72152.1 - 0.12 12.1 0.1 0.86 9.3 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain Aldo_ket_red PF00248.21 CCC72153.1 - 5.6e-62 209.6 0.2 6.7e-62 209.3 0.2 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Oxidored_FMN PF00724.20 CCC72154.1 - 8.6e-137 456.0 0.0 1e-136 455.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF5335 PF17269.2 CCC72154.1 - 0.096 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5335) Amidohydro_2 PF04909.14 CCC72155.1 - 3.6e-07 30.3 0.1 1.2e-06 28.6 0.0 1.8 1 1 1 2 2 2 1 Amidohydrolase DUF3627 PF12299.8 CCC72155.1 - 0.018 15.1 0.4 0.041 14.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3627) RepB_primase PF16793.5 CCC72155.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 RepB DNA-primase from phage plasmid Proteasom_Rpn13 PF04683.13 CCC72156.1 - 6.3e-21 74.7 0.0 9.2e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor TetR_C_23 PF17931.1 CCC72156.1 - 0.12 12.5 0.2 0.17 12.0 0.2 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DHR-2 PF06920.13 CCC72157.1 - 5.5e-38 130.9 1.9 5.5e-38 130.9 1.9 2.6 3 0 0 3 3 3 1 Dock homology region 2 DOCK_N PF16172.5 CCC72157.1 - 2.8e-06 26.5 0.1 2.3e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 DOCK N-terminus DNA_repr_REX1B PF14966.6 CCC72157.1 - 0.095 13.4 2.3 5.7 7.7 0.0 3.7 4 0 0 4 4 4 0 DNA repair REX1-B MRP-S35 PF10246.9 CCC72157.1 - 0.15 12.0 0.1 13 5.8 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial ribosomal protein MRP-S35 Tn7_Tnp_TnsA_C PF08721.11 CCC72157.1 - 4 8.2 5.4 30 5.4 0.3 3.9 3 0 0 3 3 3 0 TnsA endonuclease C terminal PP-binding PF00550.25 CCC72158.1 - 1.4e-11 44.6 0.2 1.9e-11 44.2 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 CCC72158.1 - 2e-07 31.1 0.7 2.9e-07 30.6 0.7 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1506 PF07405.11 CCC72158.1 - 0.13 12.4 0.1 0.22 11.7 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1506) APG17 PF04108.12 CCC72159.1 - 1.1e-85 288.1 17.8 1.3e-85 288.0 17.8 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 Baculo_PEP_C PF04513.12 CCC72159.1 - 0.024 14.7 5.7 0.036 14.1 0.5 3.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Myb_DNA-bind_5 PF13873.6 CCC72159.1 - 0.73 9.9 6.3 1.8 8.7 0.1 3.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain GSH_synthase PF03199.15 CCC72159.1 - 1.3 9.5 5.5 5.9 7.4 0.8 3.0 1 1 1 2 2 2 0 Eukaryotic glutathione synthase NAM-associated PF14303.6 CCC72159.1 - 6.3 7.5 8.0 12 6.6 7.7 1.7 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain Fib_alpha PF08702.10 CCC72159.1 - 9.8 6.4 28.0 0.31 11.2 7.2 4.4 2 1 3 5 5 5 0 Fibrinogen alpha/beta chain family G-patch PF01585.23 CCC72160.1 - 3.4e-12 46.1 4.7 6.4e-12 45.2 4.7 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 CCC72160.1 - 0.00017 21.6 3.0 0.00031 20.8 2.4 1.8 1 1 1 2 2 2 1 G-patch domain CHCH PF06747.13 CCC72161.1 - 4.2e-08 33.1 3.8 7.6e-08 32.3 3.8 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 CCC72161.1 - 0.0085 16.5 3.3 0.031 14.7 3.3 2.0 1 0 0 1 1 1 1 GCK domain CNH PF00780.22 CCC72162.1 - 3.2e-13 49.9 0.3 7.7e-13 48.7 0.3 1.6 1 1 0 1 1 1 1 CNH domain PH_5 PF15405.6 CCC72162.1 - 1.8e-07 31.3 0.1 0.00012 22.1 0.1 2.9 2 0 0 2 2 2 2 Pleckstrin homology domain RhoGEF PF00621.20 CCC72162.1 - 2.7e-07 31.0 0.1 8e-07 29.5 0.1 1.9 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.29 CCC72162.1 - 0.0018 18.8 0.3 0.0066 16.9 0.3 2.0 1 0 0 1 1 1 1 PH domain LMWSLP_N PF12211.8 CCC72162.1 - 0.1 12.2 0.2 0.21 11.2 0.2 1.4 1 0 0 1 1 1 0 Low molecular weight S layer protein N terminal SelP_N PF04592.14 CCC72162.1 - 2.7 7.3 9.1 5.7 6.3 9.1 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Aa_trans PF01490.18 CCC72163.1 - 8e-80 268.5 34.3 9.1e-80 268.4 34.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-RING_UBOX PF13445.6 CCC72164.1 - 2.2e-07 30.8 4.9 5.2e-07 29.6 4.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 CCC72164.1 - 3.1e-07 30.2 5.1 8.2e-07 28.8 5.1 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 CCC72164.1 - 2e-06 27.6 5.0 5.3e-06 26.3 5.1 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 CCC72164.1 - 6.7e-06 26.3 5.7 1.4e-05 25.3 5.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 CCC72164.1 - 8.8e-05 22.3 6.3 0.00044 20.0 6.3 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 CCC72164.1 - 0.0013 18.5 2.9 0.0013 18.5 2.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 CCC72164.1 - 0.0025 17.9 8.8 0.0079 16.3 8.8 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 CCC72164.1 - 0.0068 16.3 9.4 1.7 8.6 7.0 2.9 2 1 1 3 3 3 2 Prokaryotic RING finger family 4 DUF2390 PF09523.10 CCC72164.1 - 0.14 12.5 0.2 0.33 11.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) FYVE PF01363.21 CCC72164.1 - 0.55 10.4 3.2 1.6 8.9 3.1 1.8 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_10 PF16685.5 CCC72164.1 - 0.55 10.4 2.8 1.3 9.2 2.8 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 DNA_ligase_ZBD PF03119.16 CCC72164.1 - 0.64 10.1 1.9 2.2 8.4 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain zf-Nse PF11789.8 CCC72164.1 - 0.67 9.8 5.2 2 8.3 5.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Lar_restr_allev PF14354.6 CCC72164.1 - 1.1 9.7 3.7 24 5.4 0.1 2.6 2 0 0 2 2 2 0 Restriction alleviation protein Lar IBR PF01485.21 CCC72164.1 - 1.4 9.2 3.9 32 4.9 0.1 2.6 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain TerY_C PF15616.6 CCC72164.1 - 3.8 7.6 5.5 1 9.5 0.1 2.7 3 0 0 3 3 3 0 TerY-C metal binding domain DUF1899 PF08953.11 CCC72165.1 - 3.4e-32 110.1 1.6 7.2e-32 109.1 1.6 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 CCC72165.1 - 3.1e-21 75.0 0.2 7e-21 73.8 0.2 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 CCC72165.1 - 8.9e-16 58.0 5.9 0.0012 19.7 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.8 CCC72165.1 - 5.4e-09 35.2 0.0 1.4e-05 23.9 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 CCC72165.1 - 6.1e-06 26.5 0.0 0.0082 16.4 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cortex-I_coil PF09304.10 CCC72165.1 - 0.013 15.7 0.9 0.025 14.8 0.9 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil Ge1_WD40 PF16529.5 CCC72165.1 - 0.036 13.0 0.0 2.4 7.1 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SlyX PF04102.12 CCC72165.1 - 0.16 12.6 2.8 0.38 11.4 2.8 1.7 1 0 0 1 1 1 0 SlyX FixG_C PF11614.8 CCC72165.1 - 0.25 11.6 1.5 0.87 9.8 1.5 1.9 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase SEN1_N PF12726.7 CCC72166.1 - 1.6e-210 701.2 16.6 2.2e-210 700.8 16.6 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.6 CCC72166.1 - 4.5e-70 236.4 0.2 4.5e-70 236.4 0.2 3.3 3 1 0 3 3 3 1 AAA domain AAA_12 PF13087.6 CCC72166.1 - 2.9e-64 216.4 0.1 2.9e-64 216.4 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 CCC72166.1 - 1.2e-08 35.4 0.0 1.6e-07 31.8 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 CCC72166.1 - 4.7e-08 33.0 0.0 0.00027 20.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 CCC72166.1 - 0.00019 21.3 3.6 0.11 12.2 0.0 4.0 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 CCC72166.1 - 0.15 11.9 0.0 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain BAAT_C PF08840.11 CCC72167.1 - 0.088 12.7 5.2 0.061 13.2 2.2 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Metallophos PF00149.28 CCC72168.1 - 8.5e-38 130.9 0.1 2.3e-37 129.5 0.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase WGG PF10273.9 CCC72169.1 - 2.2e-27 95.5 0.5 4.5e-27 94.5 0.5 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 Hid1 PF12722.7 CCC72170.1 - 1.8e-37 129.0 78.5 8.2e-25 87.1 10.7 6.0 2 1 2 4 4 4 2 High-temperature-induced dauer-formation protein Viral_Beta_CD PF04530.12 CCC72170.1 - 0.26 11.6 3.5 1.4 9.3 0.3 3.2 3 0 0 3 3 3 0 Viral Beta C/D like family SPX PF03105.19 CCC72170.1 - 0.31 10.9 24.1 0.012 15.6 2.1 3.1 2 1 0 2 2 2 0 SPX domain RNR_inhib PF08591.10 CCC72171.1 - 4.1e-05 24.8 0.2 9.3e-05 23.7 0.2 1.8 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor DUF630 PF04783.12 CCC72171.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF630) Rop-like PF05082.13 CCC72172.1 - 0.015 15.1 0.6 0.015 15.1 0.6 1.8 2 1 0 2 2 2 0 Rop-like DUF5092 PF17010.5 CCC72172.1 - 0.11 12.4 1.3 0.57 10.1 0.9 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF5092) Aminotran_3 PF00202.21 CCC72173.1 - 1.1e-122 409.6 0.0 1.3e-122 409.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.21 CCC72173.1 - 1.5e-06 27.7 0.0 2.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 CCC72173.1 - 0.088 12.1 0.0 0.5 9.6 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family LSM PF01423.22 CCC72174.1 - 6.1e-20 70.7 0.1 6.9e-20 70.5 0.1 1.0 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 CCC72174.1 - 0.0055 16.8 0.0 0.027 14.6 0.0 1.8 1 1 0 2 2 2 1 RimP C-terminal SH3 domain TamB PF04357.13 CCC72174.1 - 0.033 13.4 0.0 0.033 13.4 0.0 1.0 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex Imm65 PF15582.6 CCC72174.1 - 0.052 12.4 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Immunity protein 65 hNIFK_binding PF12196.8 CCC72175.1 - 0.027 14.0 1.1 0.068 12.7 1.1 1.7 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK MRP-L47 PF06984.13 CCC72176.1 - 5.9e-24 84.0 2.5 7.4e-23 80.5 0.5 3.0 4 0 0 4 4 4 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) GoLoco PF02188.17 CCC72176.1 - 0.11 12.0 0.1 0.24 11.0 0.1 1.5 1 0 0 1 1 1 0 GoLoco motif Sec39 PF08314.11 CCC72177.1 - 2.6e-115 386.6 31.6 4.9e-114 382.4 31.6 2.6 1 1 0 1 1 1 1 Secretory pathway protein Sec39 Imm70 PF15601.6 CCC72177.1 - 0.057 13.0 0.1 0.2 11.2 0.1 1.9 1 0 0 1 1 1 0 Immunity protein 70 Pollen_allerg_2 PF01620.16 CCC72177.1 - 0.08 13.1 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) Ribosomal_S3Ae PF01015.18 CCC72178.1 - 8.5e-87 289.9 5.5 1e-86 289.7 5.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family DLP_helical PF18709.1 CCC72178.1 - 0.0059 15.9 0.2 0.0089 15.3 0.2 1.2 1 0 0 1 1 1 1 Dynamin-like helical domain ISAV_HA PF06215.11 CCC72178.1 - 0.023 13.9 0.1 0.027 13.6 0.1 1.2 1 0 0 1 1 1 0 Infectious salmon anaemia virus haemagglutinin HIGH_NTase1_ass PF16581.5 CCC72178.1 - 0.03 14.3 0.2 0.041 13.9 0.2 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Abhydro_lipase PF04083.16 CCC72178.1 - 0.036 13.6 0.0 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ras PF00071.22 CCC72179.1 - 2.7e-29 101.9 0.1 3.2e-29 101.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 CCC72179.1 - 6.1e-21 74.9 0.0 8.7e-21 74.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 CCC72179.1 - 1.4e-07 31.1 0.4 1.8e-07 30.7 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 CCC72179.1 - 1.7e-06 27.6 0.0 2.1e-06 27.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 CCC72179.1 - 0.00025 21.1 0.0 0.00041 20.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 CCC72179.1 - 0.0067 16.2 1.4 0.11 12.2 1.1 2.6 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 CCC72179.1 - 0.07 12.6 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 CCC72179.1 - 0.13 11.8 0.6 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_lid_10 PF17872.1 CCC72180.1 - 9.5e-22 77.0 0.0 4e-21 75.0 0.0 2.1 1 0 0 1 1 1 1 AAA lid domain BAH PF01426.18 CCC72180.1 - 2e-16 60.0 0.0 6.6e-16 58.3 0.0 2.0 1 0 0 1 1 1 1 BAH domain AAA PF00004.29 CCC72180.1 - 1.2e-10 41.9 0.0 5e-10 39.9 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 CCC72180.1 - 6.2e-07 29.8 0.0 2.2e-06 28.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 CCC72180.1 - 1.1e-06 29.2 0.1 7.5e-06 26.4 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain ATPase_2 PF01637.18 CCC72180.1 - 0.00015 21.8 0.1 0.00015 21.8 0.1 2.9 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea PIF1 PF05970.14 CCC72180.1 - 0.0054 16.0 0.0 0.025 13.8 0.0 1.9 2 0 0 2 2 2 1 PIF1-like helicase NACHT PF05729.12 CCC72180.1 - 0.028 14.3 0.0 0.066 13.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain SUR7 PF06687.12 CCC72181.1 - 1.6e-10 41.0 9.6 2.2e-10 40.5 9.6 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF5422 PF17459.2 CCC72181.1 - 0.074 13.2 0.8 0.16 12.1 0.8 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5422) hNIFK_binding PF12196.8 CCC72182.1 - 0.027 14.0 1.1 0.068 12.7 1.1 1.7 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK RNR_inhib PF08591.10 CCC72183.1 - 4.1e-05 24.8 0.2 9.3e-05 23.7 0.2 1.8 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor DUF630 PF04783.12 CCC72183.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF630) COPIIcoated_ERV PF07970.12 CCC72184.1 - 4.2e-28 98.7 0.2 7.7e-28 97.9 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 CCC72184.1 - 2e-23 82.5 0.1 2e-23 82.5 0.1 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Phosphodiest PF01663.22 CCC72185.1 - 0.02 14.5 0.2 0.028 14.0 0.2 1.4 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF4379 PF14311.6 CCC72185.1 - 5.6 7.4 7.0 57 4.2 0.1 3.2 3 0 0 3 3 3 0 Probable Zinc-ribbon domain LXG PF04740.12 CCC72186.1 - 0.002 17.9 2.1 0.0044 16.7 2.1 1.6 1 1 0 1 1 1 1 LXG domain of WXG superfamily XhlA PF10779.9 CCC72186.1 - 0.055 13.7 1.7 0.58 10.4 0.2 2.5 2 0 0 2 2 2 0 Haemolysin XhlA DUF3467 PF11950.8 CCC72186.1 - 0.12 12.6 0.2 0.32 11.2 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3467) Birna_VP3 PF01767.16 CCC72186.1 - 0.17 12.0 0.4 0.23 11.5 0.4 1.3 1 0 0 1 1 1 0 Birnavirus VP3 protein vATP-synt_AC39 PF01992.16 CCC72188.1 - 3.3e-108 362.2 3.0 3.7e-108 362.0 3.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_L6e PF01159.19 CCC72189.1 - 3.1e-36 124.3 3.8 4.6e-36 123.7 3.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Piwi PF02171.17 CCC72190.1 - 2.3e-67 227.4 0.1 3.3e-67 226.9 0.1 1.2 1 0 0 1 1 1 1 Piwi domain AGO_N PF18236.1 CCC72190.1 - 1.1e-58 196.8 0.2 1.1e-58 196.8 0.2 3.0 2 1 1 3 3 3 1 Argonaute N domain Ago_N_1 PF18351.1 CCC72190.1 - 5.6e-49 164.5 0.4 1.4e-47 160.1 0.2 3.3 2 0 0 2 2 2 1 Fungal Argonaute N-terminal domain FKBP_C PF00254.28 CCC72191.1 - 4.9e-28 97.3 0.1 2.2e-27 95.2 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 CCC72191.1 - 4.4e-20 72.2 9.7 4.4e-20 72.2 9.7 3.6 2 2 0 2 2 2 1 Nucleoplasmin-like domain Presenilin PF01080.17 CCC72191.1 - 6 5.5 30.1 1.3 7.7 7.8 2.2 2 0 0 2 2 2 0 Presenilin TFR_dimer PF04253.15 CCC72192.1 - 3.7e-14 52.9 0.0 1.2e-13 51.2 0.0 1.9 2 0 0 2 2 2 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.17 CCC72192.1 - 4e-10 39.7 0.0 7.3e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.22 CCC72192.1 - 4.8e-07 29.7 0.0 9.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-H2C2_2 PF13465.6 CCC72193.1 - 4.8e-05 23.6 10.4 6.5e-05 23.2 5.1 2.5 2 0 0 2 2 2 1 Zinc-finger double domain Lar_restr_allev PF14354.6 CCC72193.1 - 0.013 15.8 0.2 0.031 14.7 0.2 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar GP67 PF17634.2 CCC72193.1 - 0.044 14.2 0.6 0.13 12.7 0.6 1.7 1 0 0 1 1 1 0 Gene product 67 DUF3188 PF11384.8 CCC72193.1 - 0.19 11.5 0.5 0.43 10.3 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) zf-C2H2 PF00096.26 CCC72193.1 - 0.51 10.9 8.6 5.3 7.7 0.6 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Methyltransf_16 PF10294.9 CCC72194.1 - 6.6e-24 84.6 0.3 1.1e-23 83.9 0.3 1.3 1 0 0 1 1 1 1 Lysine methyltransferase Hanta_G2 PF01561.16 CCC72194.1 - 0.017 13.8 0.5 0.027 13.1 0.3 1.4 1 1 0 1 1 1 0 Hantavirus glycoprotein G2 MTS PF05175.14 CCC72194.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Glyco_hydro_47 PF01532.20 CCC72195.1 - 1.5e-138 462.5 0.6 1.7e-138 462.3 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 IBN_N PF03810.19 CCC72196.1 - 4.8e-19 68.0 0.0 4.1e-17 61.9 0.0 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain DUF4460 PF14687.6 CCC72196.1 - 0.0097 16.0 0.5 18 5.5 0.0 3.6 3 0 0 3 3 3 2 Domain of unknown function (DUF4460) DUF5503 PF17607.2 CCC72196.1 - 0.13 12.6 2.4 0.4 11.0 0.1 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5503) Utp12 PF04003.12 CCC72197.1 - 6.4e-07 29.6 0.4 1.1e-06 28.9 0.4 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Pribosyltran PF00156.27 CCC72198.1 - 2.4e-11 43.4 0.1 3.4e-11 42.9 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain MetOD2 PF18548.1 CCC72198.1 - 0.083 13.0 0.5 0.83 9.8 0.1 2.2 2 0 0 2 2 2 0 Metanogen output domain 2 TMF_TATA_bd PF12325.8 CCC72199.1 - 1.6e-35 121.8 64.5 1.2e-33 115.8 19.4 6.0 4 1 1 6 6 5 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 CCC72199.1 - 3.3e-13 49.4 91.6 6.7e-12 45.2 8.4 8.7 3 3 5 8 8 7 3 TATA element modulatory factor 1 DNA binding Lebercilin PF15619.6 CCC72199.1 - 9.4e-05 22.2 71.4 0.0038 16.9 11.3 4.1 4 0 0 4 4 4 3 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 CCC72199.1 - 0.00029 19.8 71.6 0.0098 14.8 14.1 4.5 2 1 3 5 5 5 4 Spc7 kinetochore protein APG6_N PF17675.1 CCC72199.1 - 0.0011 19.6 13.6 0.0011 19.6 13.6 5.0 3 2 2 5 5 5 2 Apg6 coiled-coil region TolA_bind_tri PF16331.5 CCC72199.1 - 0.0059 16.7 7.9 0.0059 16.7 7.9 7.1 4 2 1 6 6 6 1 TolA binding protein trimerisation ERM PF00769.19 CCC72199.1 - 0.0073 16.1 4.8 0.0073 16.1 4.8 3.6 4 0 0 4 4 4 1 Ezrin/radixin/moesin family DUF4200 PF13863.6 CCC72199.1 - 0.01 16.2 15.1 0.01 16.2 15.1 5.6 3 2 2 5 5 5 0 Domain of unknown function (DUF4200) DUF812 PF05667.11 CCC72199.1 - 0.01 14.7 66.3 0.4 9.5 12.3 3.5 2 1 1 3 3 3 0 Protein of unknown function (DUF812) DUF3138 PF11336.8 CCC72199.1 - 0.015 13.9 4.2 0.66 8.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DUF848 PF05852.11 CCC72199.1 - 0.04 14.0 46.7 0.035 14.2 7.0 4.7 2 1 0 4 4 4 0 Gammaherpesvirus protein of unknown function (DUF848) TPR_MLP1_2 PF07926.12 CCC72199.1 - 0.1 12.7 65.6 0.18 11.9 16.1 5.4 3 3 2 5 5 5 0 TPR/MLP1/MLP2-like protein DUF724 PF05266.14 CCC72199.1 - 0.12 12.2 53.6 0.084 12.7 4.3 5.6 3 2 2 5 5 5 0 Protein of unknown function (DUF724) HMMR_N PF15905.5 CCC72199.1 - 0.13 11.7 75.7 0.52 9.7 14.9 4.0 3 1 0 3 3 3 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 CCC72199.1 - 0.21 12.1 63.8 0.43 11.0 16.2 4.5 2 1 2 4 4 4 0 Fez1 AvrPto PF11592.8 CCC72199.1 - 0.33 11.0 5.5 0.67 10.0 0.0 4.0 5 0 0 5 5 5 0 Central core of the bacterial effector protein AvrPto Phage_GP20 PF06810.11 CCC72199.1 - 0.43 10.4 62.3 2.9 7.7 5.8 5.3 3 2 1 4 4 4 0 Phage minor structural protein GP20 GAS PF13851.6 CCC72199.1 - 1.2 8.5 79.7 0.52 9.6 21.5 4.6 3 2 1 4 4 4 0 Growth-arrest specific micro-tubule binding HOOK PF05622.12 CCC72199.1 - 2 6.4 68.6 0.2 9.8 15.6 4.3 2 1 1 4 4 4 0 HOOK protein Atg14 PF10186.9 CCC72199.1 - 2.9 6.9 63.9 0.22 10.6 17.4 3.9 2 1 1 4 4 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 IFT57 PF10498.9 CCC72199.1 - 4.1 6.3 58.8 0.16 10.9 15.3 4.0 3 1 1 4 4 4 0 Intra-flagellar transport protein 57 DPM3 PF08285.11 CCC72199.1 - 4.1 7.7 12.5 1.4 9.2 0.3 4.1 3 1 1 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) CENP-F_leu_zip PF10473.9 CCC72199.1 - 5 7.1 80.6 0.23 11.5 15.3 6.1 3 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3584 PF12128.8 CCC72199.1 - 5.5 4.4 59.5 0.5 7.8 27.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) Rootletin PF15035.6 CCC72199.1 - 7.9 6.5 59.4 0.27 11.3 10.2 4.7 2 1 2 4 4 4 0 Ciliary rootlet component, centrosome cohesion Muted PF14942.6 CCC72200.1 - 0.02 15.2 4.2 0.02 15.2 4.2 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Importin_rep_6 PF18829.1 CCC72200.1 - 5.2 7.3 10.7 0.088 12.9 2.1 2.3 2 1 0 2 2 2 0 Importin repeat 6 zf-Tim10_DDP PF02953.15 CCC72201.1 - 4.6e-19 67.8 4.6 5.9e-19 67.5 4.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Torsin PF06309.11 CCC72201.1 - 0.0056 16.8 0.0 0.0065 16.6 0.0 1.1 1 0 0 1 1 1 1 Torsin Tti2 PF10521.9 CCC72202.1 - 1.4e-51 175.7 6.8 1.9e-51 175.3 6.8 1.2 1 0 0 1 1 1 1 Tti2 family Aminotran_4 PF01063.19 CCC72203.1 - 4.2e-35 121.6 0.0 5.2e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Ribosomal_S4e PF00900.20 CCC72204.1 - 5.7e-39 131.9 1.3 4.8e-38 128.9 1.0 2.2 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 CCC72204.1 - 1.4e-25 88.7 0.0 2.8e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 CCC72204.1 - 2.4e-19 69.2 6.9 2.4e-19 69.2 6.9 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 CCC72204.1 - 4.3e-08 32.7 0.6 8.5e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 S4 domain KOW PF00467.29 CCC72204.1 - 4.1e-06 26.5 1.8 4.1e-06 26.5 1.8 3.0 4 0 0 4 4 4 1 KOW motif DUF5072 PF16807.5 CCC72204.1 - 0.05 13.7 0.1 0.61 10.2 0.0 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5072) dCache_2 PF08269.11 CCC72204.1 - 0.051 12.8 0.1 0.13 11.4 0.0 1.7 1 1 0 1 1 1 0 Cache domain PMT PF02366.18 CCC72205.1 - 3.3e-79 265.9 22.1 3.3e-79 265.9 22.1 2.0 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase PMT_4TMC PF16192.5 CCC72205.1 - 6.7e-58 195.6 5.9 6.7e-58 195.6 5.9 3.5 3 1 0 3 3 3 2 C-terminal four TMM region of protein-O-mannosyltransferase MIR PF02815.19 CCC72205.1 - 3.6e-17 62.8 0.1 5.9e-17 62.1 0.1 1.2 1 0 0 1 1 1 1 MIR domain YlaC PF10777.9 CCC72205.1 - 4.1 7.2 6.6 6.5 6.6 0.7 3.3 3 0 0 3 3 3 0 Inner membrane protein YlaC NUDIX PF00293.28 CCC72206.1 - 1.1e-08 35.1 0.0 2.3e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4743 PF15916.5 CCC72206.1 - 1.4e-07 31.5 0.1 2.5e-07 30.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) HECT_2 PF09814.9 CCC72207.1 - 9.4e-69 232.1 0.2 1.1e-68 231.9 0.2 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding RIG-I_C-RD PF11648.8 CCC72207.1 - 0.059 13.6 0.4 1.1 9.6 0.1 2.5 2 0 0 2 2 2 0 C-terminal domain of RIG-I Mut7-C PF01927.16 CCC72207.1 - 0.097 12.8 0.1 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Mut7-C RNAse domain Big_3_2 PF12245.8 CCC72208.1 - 0.16 12.3 0.1 0.36 11.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial Ig-like domain IML1 PF12257.8 CCC72209.1 - 2.6e-106 354.9 1.1 5.6e-106 353.8 1.1 1.6 1 0 0 1 1 1 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 CCC72209.1 - 9.3e-26 89.7 0.6 9.3e-26 89.7 0.6 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NIR_SIR PF01077.22 CCC72210.1 - 1.6e-50 170.8 0.0 1.6e-47 160.9 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 CCC72210.1 - 3.8e-28 97.1 0.0 6.9e-13 48.3 0.0 2.9 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.25 CCC72210.1 - 1.1e-26 93.8 0.0 2.3e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Sir1 PF11603.8 CCC72211.1 - 2.3e-59 199.1 11.4 6.3e-29 100.9 3.1 4.1 3 1 0 3 3 3 3 Regulatory protein Sir1 CLAMP PF14769.6 CCC72211.1 - 0.0039 17.6 4.6 0.038 14.4 0.0 3.5 3 0 0 3 3 3 1 Flagellar C1a complex subunit C1a-32 Hyphal_reg_CWP PF11765.8 CCC72212.1 - 5.2e-84 282.0 12.4 5.2e-84 282.0 12.4 2.8 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal DUF2000 PF09391.10 CCC72212.1 - 0.04 13.8 0.2 23 4.9 0.0 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF2000) COX7B PF05392.11 CCC72212.1 - 0.12 12.1 0.8 1.1 8.9 0.0 2.8 2 1 1 3 3 3 0 Cytochrome C oxidase chain VIIB PRP21_like_P PF12230.8 CCC72213.1 - 2e-35 122.6 13.8 1.4e-24 87.2 6.8 2.1 1 1 1 2 2 2 2 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 CCC72213.1 - 0.0016 18.4 0.2 0.0039 17.2 0.2 1.8 1 1 0 1 1 1 1 Surp module Hyphal_reg_CWP PF11765.8 CCC72214.1 - 1e-14 54.3 0.7 1e-14 54.3 0.7 1.6 2 0 0 2 2 2 1 Hyphally regulated cell wall protein N-terminal PI31_Prot_N PF11566.8 CCC72215.1 - 0.11 12.3 0.1 0.3 10.9 0.1 1.7 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal ArfGap PF01412.18 CCC86749.1 - 3.1e-30 104.6 3.1 3.1e-30 104.6 3.1 3.9 3 1 0 4 4 4 2 Putative GTPase activating protein for Arf PH PF00169.29 CCC86749.1 - 6.2e-07 29.9 5.9 1.4e-06 28.7 3.9 2.6 2 0 0 2 2 2 1 PH domain PH_9 PF15410.6 CCC86749.1 - 0.4 11.1 6.8 5.2 7.5 6.5 3.0 1 1 0 1 1 1 0 Pleckstrin homology domain PX PF00787.24 CCC86750.1 - 4.6e-25 87.8 3.8 4.7e-25 87.8 0.3 2.5 3 0 0 3 3 2 1 PX domain Vps5 PF09325.10 CCC86750.1 - 0.0015 18.1 19.7 0.0025 17.4 6.4 2.7 2 1 1 3 3 3 2 Vps5 C terminal like DUF2316 PF10078.9 CCC86750.1 - 0.0094 16.2 0.7 0.34 11.2 0.0 2.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2316) RPW8 PF05659.11 CCC86750.1 - 0.026 14.2 0.7 0.026 14.2 0.7 3.2 3 1 0 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 MCC-bdg_PDZ PF10506.9 CCC86750.1 - 0.069 13.2 6.6 3.2 7.8 0.6 3.2 3 0 0 3 3 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF4407 PF14362.6 CCC86750.1 - 0.1 11.9 2.4 3.1 7.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PilJ PF13675.6 CCC86750.1 - 0.14 12.2 0.9 0.75 9.8 0.0 2.5 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term T3SSipB PF16535.5 CCC86750.1 - 0.2 12.1 5.1 0.6 10.6 0.8 2.3 2 0 0 2 2 2 0 Type III cell invasion protein SipB Dor1 PF04124.12 CCC86750.1 - 0.25 10.0 8.2 0.034 12.9 1.3 2.2 2 0 0 2 2 2 0 Dor1-like family Vps51 PF08700.11 CCC86750.1 - 0.43 10.7 7.3 0.1 12.7 0.4 3.3 3 1 0 3 3 3 0 Vps51/Vps67 FlaC_arch PF05377.11 CCC86750.1 - 0.66 10.4 12.5 0.14 12.6 0.9 3.2 3 0 0 3 3 2 0 Flagella accessory protein C (FlaC) DUF3970 PF13113.6 CCC86750.1 - 0.89 9.8 4.8 3.3 8.0 0.9 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) DUF3552 PF12072.8 CCC86750.1 - 1 8.7 13.1 0.067 12.6 3.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Fez1 PF06818.15 CCC86750.1 - 2 8.8 13.4 10 6.5 12.7 2.1 1 1 0 1 1 1 0 Fez1 DUF4795 PF16043.5 CCC86750.1 - 2.4 7.7 16.3 1.4 8.4 7.4 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Remorin_C PF03763.13 CCC86750.1 - 2.9 7.8 9.9 5.3 7.0 2.1 2.5 2 0 0 2 2 2 0 Remorin, C-terminal region NPV_P10 PF05531.12 CCC86750.1 - 3.3 8.2 12.1 1.4 9.4 0.9 4.0 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 CCC86750.1 - 4.2 7.4 8.1 1 9.4 1.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.21 CCC86750.1 - 4.2 7.2 9.2 12 5.8 0.8 2.6 2 0 0 2 2 2 0 Synaptobrevin CLZ PF16526.5 CCC86750.1 - 4.7 7.6 12.3 1.1 9.7 1.4 3.4 3 1 1 4 4 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels HemX PF04375.14 CCC86750.1 - 4.9 6.3 10.8 1.8 7.8 1.8 2.3 2 1 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Tropomyosin_1 PF12718.7 CCC86750.1 - 5.6 7.1 21.0 0.05 13.8 4.3 2.9 2 1 1 3 3 3 0 Tropomyosin like Occludin_ELL PF07303.13 CCC86750.1 - 5.6 7.7 14.1 0.48 11.2 1.8 3.1 3 0 0 3 3 3 0 Occludin homology domain Sec34 PF04136.15 CCC86750.1 - 5.6 6.8 14.0 0.49 10.3 5.3 2.6 2 1 0 2 2 2 0 Sec34-like family Fib_alpha PF08702.10 CCC86750.1 - 7.6 6.7 17.9 2.4 8.4 3.5 3.1 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Rootletin PF15035.6 CCC86750.1 - 7.8 6.5 12.8 0.21 11.6 0.6 2.6 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion CENP-F_leu_zip PF10473.9 CCC86750.1 - 9.6 6.2 21.7 1.3 9.0 5.3 3.0 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Brr6_like_C_C PF10104.9 CCC86751.1 - 2.9e-40 137.1 6.4 4.6e-40 136.5 6.4 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF4658 PF15555.6 CCC86751.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Naumovozyma_castellii_CBS4309-ASM23734v1/GCA_000237345.1_ASM23734v1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Naumovozyma_castellii_CBS4309-ASM23734v1/GCA_000237345.1_ASM23734v1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Naumovozyma_castellii_CBS4309-ASM23734v1/GCA_000237345.1_ASM23734v1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Fungi/Naumovozyma_castellii_CBS4309-ASM23734v1/GCA_000237345.1_ASM23734v1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 01:00:47 2019 # [ok]