# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Sir1 PF11603.3 CCC66571.1 - 9.9e-06 25.7 0.0 1.5e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Regulatory protein Sir1 Pex14_N PF04695.8 CCC66573.1 - 1.2 9.2 9.1 0.076 13.0 2.9 1.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GST_C PF00043.20 CCC66574.1 - 1.1e-09 38.1 0.1 1.8e-09 37.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCC66574.1 - 1.8e-05 24.5 0.0 3.7e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCC66574.1 - 0.0039 17.3 0.0 0.0073 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCC66574.1 - 0.025 15.0 0.1 0.053 14.0 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PA14 PF07691.7 CCC66575.1 - 8e-35 119.6 4.4 8.1e-13 48.2 0.0 4.0 3 0 0 3 3 3 3 PA14 domain PA14_2 PF10528.4 CCC66575.1 - 1.2e-26 92.8 28.0 1.1e-09 38.2 0.9 4.8 4 0 0 4 4 4 3 GLEYA domain Flocculin PF00624.13 CCC66575.1 - 1.4e-10 40.8 73.2 2.2e-06 27.3 15.5 12.5 12 3 1 13 13 13 3 Flocculin repeat Golgin_A5 PF09787.4 CCC66575.1 - 9.8 4.5 7.6 15 3.9 5.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Sec10 PF07393.6 CCC66576.1 - 3.4e-62 210.6 25.8 4.3e-62 210.3 17.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 RNA_pol_Rpb1_5 PF04998.12 CCC66576.1 - 0.0011 18.3 2.0 0.0021 17.4 1.4 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 Endonuclease_NS PF01223.18 CCC66578.1 - 5.4e-57 192.7 0.0 6.9e-57 192.4 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease FAM150 PF15129.1 CCC66578.1 - 0.021 14.7 0.0 0.058 13.2 0.0 1.7 2 0 0 2 2 2 0 FAM150 family CENP-B_dimeris PF09026.5 CCC66580.1 - 0.26 11.5 3.6 0.57 10.4 2.5 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain UCR_14kD PF02271.11 CCC66581.1 - 1.9e-42 143.3 0.1 2.1e-42 143.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit DinB PF05163.7 CCC66581.1 - 0.11 12.1 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 DinB family ATP_transf PF09830.4 CCC66582.1 - 8.6e-15 54.2 0.0 1.6e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 CCC66582.1 - 0.0095 16.4 0.0 0.028 14.9 0.0 1.7 1 0 0 1 1 1 1 HIT domain Fumble PF03630.9 CCC66583.1 - 2.1e-123 411.5 10.2 1.5e-120 402.1 4.1 2.5 1 1 1 2 2 2 2 Fumble DUF2082 PF09855.4 CCC66583.1 - 0.033 14.0 1.1 0.2 11.5 0.0 2.6 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) LPP PF04728.8 CCC66584.1 - 0.033 13.9 2.4 0.14 11.9 1.7 2.1 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF2937 PF11157.3 CCC66584.1 - 0.13 11.5 3.1 3.9 6.7 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2937) DUF4315 PF14193.1 CCC66584.1 - 0.4 10.6 12.1 0.99 9.3 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4315) Adenylsucc_synt PF00709.16 CCC66584.1 - 5.3 5.5 7.8 0.31 9.6 0.3 2.1 1 1 0 2 2 2 0 Adenylosuccinate synthetase RPAP1_C PF08620.5 CCC66585.1 - 5e-32 109.5 0.1 1.2e-31 108.3 0.0 1.7 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 CCC66585.1 - 2.3e-13 49.4 5.8 2.3e-13 49.4 4.1 3.0 4 0 0 4 4 4 1 RPAP1-like, N-terminal HEAT PF02985.17 CCC66585.1 - 0.021 14.8 0.0 0.071 13.2 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat OmpH PF03938.9 CCC66585.1 - 0.078 12.9 8.0 0.14 12.0 5.5 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TFIIA PF03153.8 CCC66585.1 - 0.1 12.5 19.8 0.2 11.5 13.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SR-25 PF10500.4 CCC66585.1 - 0.91 8.9 13.7 1.6 8.1 9.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pmp3 PF01679.12 CCC66586.1 - 3.6e-22 77.8 5.1 4.1e-22 77.6 3.5 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SSP160 PF06933.6 CCC66587.1 - 0.056 11.4 13.4 0.066 11.1 9.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF844 PF05815.6 CCC66587.1 - 0.31 9.8 1.7 0.33 9.7 1.2 1.0 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) QCR10 PF09796.4 CCC66587.1 - 0.94 9.1 3.0 1.8 8.2 2.1 1.5 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Pkinase PF00069.20 CCC66588.1 - 9.1e-64 215.1 0.0 1.4e-63 214.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC66588.1 - 1e-46 159.1 0.0 1.4e-46 158.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC66588.1 - 1.3e-09 37.4 0.0 1.5e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Recep_L_domain PF01030.19 CCC66589.1 - 1.1e-08 35.0 11.7 0.0025 17.7 0.0 4.5 1 1 3 4 4 4 3 Receptor L domain Zn_clus PF00172.13 CCC66590.1 - 7.5e-06 25.7 5.8 1.4e-05 24.8 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FKBP_C PF00254.23 CCC66591.1 - 2.8e-33 113.7 0.0 3.9e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Thioredoxin PF00085.15 CCC66592.1 - 6.9e-41 138.1 0.5 2.8e-19 68.7 0.0 3.6 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 CCC66592.1 - 5.2e-17 62.2 8.2 2.8e-13 50.0 0.8 3.8 3 1 1 4 4 4 4 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CCC66592.1 - 0.0033 17.4 0.3 0.13 12.2 0.0 3.1 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin_8 PF13905.1 CCC66592.1 - 0.018 15.1 3.8 1.4 9.0 0.0 4.6 4 3 0 4 4 4 0 Thioredoxin-like GRASP55_65 PF04495.9 CCC66593.1 - 3.7e-33 114.4 0.0 3.9e-32 111.1 0.0 2.1 1 1 0 2 2 2 1 GRASP55/65 PDZ-like domain Hexokinase_2 PF03727.11 CCC66594.1 - 1.2e-76 257.1 0.0 1.6e-76 256.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCC66594.1 - 5.4e-66 221.8 0.2 3.6e-65 219.1 0.1 2.0 1 1 0 1 1 1 1 Hexokinase Glyco_hydro_4C PF11975.3 CCC66595.1 - 0.015 15.1 0.3 0.026 14.3 0.2 1.3 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain RNase_T PF00929.19 CCC66595.1 - 0.035 14.4 0.0 0.088 13.0 0.0 1.7 1 0 0 1 1 1 0 Exonuclease Glutaredoxin PF00462.19 CCC66596.1 - 7.5e-13 48.2 0.0 1.2e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 CCC66596.1 - 0.0024 17.4 0.1 0.0035 16.9 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin Chordopox_G3 PF06129.7 CCC66596.1 - 0.018 15.1 0.5 0.026 14.6 0.3 1.3 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Thioredoxin_7 PF13899.1 CCC66596.1 - 0.025 14.6 0.0 0.047 13.7 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like DUF1682 PF07946.9 CCC66596.1 - 0.064 12.0 0.6 0.38 9.5 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1682) DUF1904 PF08921.6 CCC66596.1 - 0.088 12.8 0.4 0.94 9.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1904) DUF3128 PF11326.3 CCC66597.1 - 1.5e-30 105.1 2.1 1.7e-30 104.9 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Pet191_N PF10203.4 CCC66597.1 - 1.2 9.2 3.9 0.75 9.8 0.2 2.1 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Complex1_LYR PF05347.10 CCC66598.1 - 7.8e-10 38.4 0.0 4e-09 36.1 0.0 2.1 3 0 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCC66598.1 - 2.5e-09 37.2 0.0 8.3e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 CCC66598.1 - 0.0002 21.7 0.1 0.00028 21.3 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Voldacs PF03517.8 CCC66598.1 - 0.094 12.5 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling PMT_C PF11647.3 CCC66598.1 - 0.4 10.3 0.1 0.4 10.3 0.1 2.4 3 0 0 3 3 3 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 THP2 PF09432.5 CCC66601.1 - 0.0005 19.9 1.2 0.0011 18.8 0.8 1.5 1 0 0 1 1 1 1 Tho complex subunit THP2 PspA_IM30 PF04012.7 CCC66601.1 - 0.0072 15.7 0.8 0.011 15.1 0.5 1.2 1 0 0 1 1 1 1 PspA/IM30 family YbaJ PF10757.4 CCC66601.1 - 0.0099 16.0 0.5 0.2 11.8 0.0 2.3 1 1 1 2 2 2 1 Biofilm formation regulator YbaJ DUF869 PF05911.6 CCC66601.1 - 0.027 12.7 0.5 0.033 12.4 0.4 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Rhabdo_M1 PF03342.8 CCC66601.1 - 0.045 12.8 0.1 0.072 12.2 0.1 1.3 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) APG6 PF04111.7 CCC66601.1 - 0.052 12.5 2.5 0.07 12.1 1.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF641 PF04859.7 CCC66601.1 - 0.08 12.7 1.7 0.13 12.0 1.2 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Nsp1_C PF05064.8 CCC66601.1 - 0.1 12.2 3.8 0.12 11.9 0.6 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region IncA PF04156.9 CCC66601.1 - 0.17 11.4 5.3 0.3 10.6 3.3 1.6 1 1 0 1 1 1 0 IncA protein BLOC1_2 PF10046.4 CCC66601.1 - 0.27 11.3 4.5 0.36 10.9 1.0 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Occludin_ELL PF07303.8 CCC66601.1 - 0.58 10.9 4.1 2.7 8.7 2.7 1.9 1 1 1 2 2 2 0 Occludin homology domain AA_permease PF00324.16 CCC66602.1 - 3.4e-119 398.3 37.7 4e-119 398.0 26.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC66602.1 - 5.9e-29 100.8 36.0 7.3e-29 100.5 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease Colicin_im PF03857.8 CCC66602.1 - 0.88 9.3 5.2 0.22 11.2 0.8 2.1 2 0 0 2 2 2 0 Colicin immunity protein PSP1 PF04468.7 CCC66603.1 - 1.4e-35 121.1 0.9 2.8e-35 120.1 0.6 1.6 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PAP2 PF01569.16 CCC66604.1 - 4.1e-21 75.0 2.2 6.1e-21 74.4 0.6 1.9 2 0 0 2 2 2 1 PAP2 superfamily FUSC_2 PF13515.1 CCC66604.1 - 0.002 18.0 2.4 0.002 18.0 1.7 2.4 3 0 0 3 3 3 1 Fusaric acid resistance protein-like PAP2_C PF14360.1 CCC66604.1 - 0.0022 18.2 7.6 0.0022 18.2 5.3 3.0 4 0 0 4 4 4 1 PAP2 superfamily C-terminal S-AdoMet_synt_C PF02773.11 CCC66605.1 - 3.9e-75 250.1 0.2 6.6e-75 249.4 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CCC66605.1 - 1.5e-46 157.2 0.0 2.6e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CCC66605.1 - 6.8e-44 148.1 0.9 8.6e-44 147.8 0.1 1.6 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain FHA PF00498.21 CCC66606.1 - 0.0074 16.3 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain Ribosomal_L37e PF01907.14 CCC66607.1 - 6.8e-27 93.0 11.5 6.8e-27 93.0 7.9 1.6 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 CCC66607.1 - 0.00047 19.9 2.3 0.00068 19.4 1.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 CCC66607.1 - 0.0096 15.6 0.5 0.012 15.3 0.3 1.3 1 1 0 1 1 1 1 SelR domain C1_1 PF00130.17 CCC66607.1 - 0.04 13.6 2.3 0.066 12.9 1.6 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 CCC66607.1 - 0.046 13.4 3.2 0.07 12.8 2.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain GATA PF00320.22 CCC66607.1 - 0.088 12.1 6.4 0.52 9.7 0.9 2.4 1 1 1 2 2 2 0 GATA zinc finger zinc_ribbon_6 PF14599.1 CCC66607.1 - 0.12 12.1 1.8 0.18 11.6 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon C1_3 PF07649.7 CCC66607.1 - 0.22 11.5 1.5 3.1 7.9 0.1 2.2 2 0 0 2 2 2 0 C1-like domain zf-C3HC4_3 PF13920.1 CCC66607.1 - 0.22 11.1 2.6 0.31 10.7 1.8 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 CCC66607.1 - 0.35 10.1 5.0 0.75 9.0 0.6 2.1 1 1 2 3 3 3 0 zinc-ribbon domain GCC2_GCC3 PF07699.8 CCC66607.1 - 0.68 9.5 4.8 1.2 8.7 3.3 1.6 1 1 0 1 1 1 0 GCC2 and GCC3 zf-C3HC4_2 PF13923.1 CCC66607.1 - 0.91 9.6 4.8 1.4 8.9 3.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCC66607.1 - 1.2 8.8 4.9 1.9 8.2 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 CCC66607.1 - 1.6 8.2 5.7 38 3.9 0.2 2.2 1 1 1 2 2 2 0 zinc-ribbon domain DUF2256 PF10013.4 CCC66607.1 - 5.8 6.7 8.9 3.3 7.5 1.6 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) LCD1 PF09798.4 CCC66608.1 - 1.3e-178 595.0 23.8 1.6e-178 594.7 16.5 1.1 1 0 0 1 1 1 1 DNA damage checkpoint protein DUF342 PF03961.8 CCC66608.1 - 0.3 9.4 7.1 0.57 8.5 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TPR_11 PF13414.1 CCC66609.1 - 2.1e-43 145.8 17.1 1.2e-11 44.0 0.0 6.3 6 0 0 6 6 6 5 TPR repeat TPR_1 PF00515.23 CCC66609.1 - 4.6e-27 92.4 22.5 5e-07 29.0 0.2 10.1 9 1 0 9 9 9 6 Tetratricopeptide repeat TPR_2 PF07719.12 CCC66609.1 - 1.8e-25 86.7 18.5 1.6e-05 24.4 0.2 9.3 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_12 PF13424.1 CCC66609.1 - 2.1e-12 46.8 15.0 8.1e-05 22.4 0.0 6.6 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCC66609.1 - 2.1e-07 30.5 9.6 2.6 8.4 0.0 7.4 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCC66609.1 - 3.9e-07 30.5 2.8 0.062 13.9 0.6 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCC66609.1 - 4.7e-07 29.8 0.2 0.11 13.1 0.0 5.6 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCC66609.1 - 7.8e-07 29.3 6.8 0.12 12.6 1.6 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCC66609.1 - 2e-05 24.0 6.2 3.2 7.7 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCC66609.1 - 0.0043 16.7 0.2 0.0043 16.7 0.1 6.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCC66609.1 - 0.0079 16.0 0.0 12 5.8 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCC66609.1 - 0.048 13.5 4.9 2.1 8.3 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCC66609.1 - 0.17 12.3 2.6 1.8e+02 2.9 0.0 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat EMG1 PF03587.9 CCC66610.1 - 5.1e-76 254.4 0.0 6e-76 254.2 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase phiKZ_IP PF12699.2 CCC66611.1 - 0.00013 20.9 0.4 0.00027 19.9 0.1 1.6 2 0 0 2 2 2 1 phiKZ-like phage internal head proteins Baculo_11_kDa PF06143.6 CCC66611.1 - 0.2 11.0 3.3 1.5 8.2 0.0 2.9 3 0 0 3 3 3 0 Baculovirus 11 kDa family Pox_I5 PF04713.7 CCC66611.1 - 0.73 9.5 6.5 0.81 9.4 0.1 2.9 3 0 0 3 3 3 0 Poxvirus protein I5 DUF4492 PF14899.1 CCC66611.1 - 1.5 8.3 9.5 0.15 11.6 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4492) ApoLp-III PF07464.6 CCC66611.1 - 4.5 7.2 6.9 1.6 8.7 0.3 2.9 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) PH PF00169.24 CCC66612.1 - 6.9e-09 35.8 0.1 1.2e-07 31.8 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 CCC66612.1 - 0.015 15.4 0.2 0.068 13.3 0.1 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Abhydrolase_1 PF00561.15 CCC66614.1 - 4.4e-63 212.9 0.0 5.8e-63 212.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCC66614.1 - 4.9e-13 49.4 0.2 8.1e-12 45.5 0.2 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCC66614.1 - 0.00047 19.9 0.0 0.017 14.8 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 CCC66614.1 - 0.027 14.3 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.8 CCC66614.1 - 0.087 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein HCO3_cotransp PF00955.16 CCC66615.1 - 3.5e-59 200.8 10.2 1.1e-34 120.0 1.9 2.1 1 1 1 2 2 2 2 HCO3- transporter family BacA PF02673.13 CCC66615.1 - 0.63 9.1 9.0 1.4 8.0 0.0 3.6 3 1 1 4 4 4 0 Bacitracin resistance protein BacA 2-Hacid_dh_C PF02826.14 CCC66616.1 - 1e-54 184.4 0.0 1.9e-54 183.5 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCC66616.1 - 2.9e-16 59.1 0.0 4e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCC66616.1 - 2.1e-06 27.6 0.0 7.7e-06 25.8 0.0 2.0 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 CCC66616.1 - 9.7e-05 21.7 0.1 0.0005 19.4 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 CCC66616.1 - 0.0025 17.9 0.0 0.007 16.4 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 CCC66616.1 - 0.003 17.3 1.9 0.39 10.5 0.1 3.1 2 1 1 3 3 3 1 ThiF family AgrD PF05931.6 CCC66616.1 - 0.03 13.9 0.4 0.056 13.0 0.3 1.4 1 0 0 1 1 1 0 Staphylococcal AgrD protein AlaDh_PNT_C PF01262.16 CCC66616.1 - 0.038 13.5 0.4 0.2 11.1 0.0 2.1 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain TIMELESS PF04821.9 CCC66617.1 - 1.7e-46 158.6 5.3 1.7e-46 158.6 3.7 2.3 2 0 0 2 2 2 1 Timeless protein Hjc PF01870.13 CCC66617.1 - 0.045 13.3 0.6 1.8 8.2 0.1 2.7 2 0 0 2 2 2 0 Archaeal holliday junction resolvase (hjc) Sec2p PF06428.6 CCC66618.1 - 1.7e-26 91.9 12.0 1.7e-26 91.9 8.3 3.9 3 1 0 3 3 3 2 GDP/GTP exchange factor Sec2p FH2 PF02181.18 CCC66619.1 - 1.3e-88 297.3 11.3 1.3e-88 297.3 7.9 4.7 2 1 2 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 CCC66619.1 - 2.6e-49 167.3 4.7 2.6e-49 167.3 3.3 3.7 4 0 0 4 4 4 2 Diaphanous FH3 Domain Drf_GBD PF06371.8 CCC66619.1 - 6.3e-26 90.8 5.7 1.2e-19 70.4 0.0 5.4 6 0 0 6 6 6 2 Diaphanous GTPase-binding Domain AA_permease PF00324.16 CCC66620.1 - 1.9e-134 448.6 54.5 2.1e-134 448.4 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC66620.1 - 7.1e-31 107.1 62.9 1.2e-30 106.4 43.4 1.4 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCC66621.1 - 4.5e-131 437.4 48.0 5.1e-131 437.2 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC66621.1 - 6.1e-32 110.7 58.7 1.3e-31 109.5 40.7 1.5 1 1 0 1 1 1 1 Amino acid permease RhodobacterPufX PF11511.3 CCC66621.1 - 0.13 11.6 2.5 7.2 6.0 0.4 3.2 2 0 0 2 2 2 0 Intrinsic membrane protein PufX PI3_PI4_kinase PF00454.22 CCC66622.1 - 2.5e-32 112.2 0.0 6.1e-32 110.9 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 CCC66622.1 - 2.7e-20 71.8 2.8 5.4e-20 70.8 0.2 2.6 2 0 0 2 2 2 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 CCC66622.1 - 7.1e-07 28.5 1.4 2e-06 27.1 1.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Ist1 PF03398.9 CCC66623.1 - 7.5e-59 197.8 1.8 7.5e-59 197.8 1.2 1.8 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway NOA36 PF06524.7 CCC66623.1 - 0.34 10.1 4.8 0.71 9.0 3.3 1.5 1 0 0 1 1 1 0 NOA36 protein CRAL_TRIO PF00650.15 CCC66624.1 - 1.4e-39 135.1 0.0 2.3e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCC66624.1 - 4.4e-09 36.3 0.1 1.3e-08 34.8 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCC66624.1 - 7.6e-06 25.9 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain YIF1 PF03878.10 CCC66625.1 - 1.9e-68 230.2 4.0 2.3e-68 229.9 2.8 1.1 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 CCC66625.1 - 0.015 14.7 9.1 0.029 13.8 6.3 1.5 1 1 0 1 1 1 0 Yip1 domain DUF1744 PF08490.7 CCC66626.1 - 1.1e-148 495.0 6.2 1.8e-148 494.3 4.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 CCC66626.1 - 4.2e-68 229.6 7.0 1e-67 228.3 4.9 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 CCC66626.1 - 9.9e-22 77.3 1.1 9.9e-22 77.3 0.8 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 CCC66626.1 - 1.4e-08 34.5 0.4 1e-07 31.6 0.3 2.3 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB Yae1_N PF09811.4 CCC66627.1 - 4.7e-09 35.6 1.2 4.7e-09 35.6 0.8 1.8 2 0 0 2 2 2 1 Essential protein Yae1, N terminal Fib_alpha PF08702.5 CCC66627.1 - 0.35 10.9 1.9 4.2 7.4 1.3 2.1 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family HMA PF00403.21 CCC66628.1 - 3.2e-11 43.1 0.1 3.8e-11 42.9 0.1 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Dsl1_C PF11989.3 CCC66629.1 - 3.6e-104 348.0 14.1 3.6e-104 348.0 9.8 3.0 3 1 1 4 4 4 1 Retrograde transport protein Dsl1 C terminal Dsl1_N PF11988.3 CCC66629.1 - 8.2e-100 334.1 24.4 1.6e-99 333.1 16.9 1.5 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 N terminal COPI_C PF06957.6 CCC66629.1 - 0.029 12.9 9.8 0.052 12.0 6.8 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus PH PF00169.24 CCC66630.1 - 2.2e-09 37.4 0.6 6.9e-08 32.6 0.1 3.1 2 0 0 2 2 2 1 PH domain Pterin_bind PF00809.17 CCC66631.1 - 2.6e-43 147.8 0.0 3e-41 141.0 0.0 2.5 1 1 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 CCC66631.1 - 4.3e-38 129.9 0.0 8.7e-38 128.9 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 CCC66631.1 - 1.4e-32 112.1 0.5 1.3e-15 57.5 0.0 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase zf-CCHC PF00098.18 CCC66632.1 - 1.1e-56 186.1 54.2 8.2e-09 34.9 0.9 7.1 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 CCC66632.1 - 1.1e-12 47.3 47.3 0.0023 17.5 0.7 7.1 6 1 1 7 7 7 7 Zinc knuckle zf-CCHC_2 PF13696.1 CCC66632.1 - 1.4e-09 37.2 46.2 0.013 14.9 1.2 7.1 2 2 5 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 CCC66632.1 - 2.1e-06 27.3 46.0 0.35 10.6 0.5 7.0 2 2 5 7 7 7 7 Zinc knuckle zf-CCHC_6 PF15288.1 CCC66632.1 - 0.013 15.1 2.6 0.013 15.1 1.8 7.0 6 1 1 7 7 7 0 Zinc knuckle RTC4 PF14474.1 CCC66633.1 - 5.2e-33 113.6 0.0 1.2e-32 112.4 0.0 1.7 1 0 0 1 1 1 1 RTC4-like domain WD40 PF00400.27 CCC66634.1 - 2.1e-20 71.7 5.0 1.1e-05 25.0 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat MMS1_N PF10433.4 CCC66634.1 - 5e-07 28.2 0.2 0.0013 16.9 0.3 3.0 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term eIF2A PF08662.6 CCC66634.1 - 0.0076 15.9 0.1 0.067 12.8 0.0 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 CCC66634.1 - 0.68 9.1 2.5 4.4 6.4 0.0 3.1 3 1 1 4 4 4 0 TUP1-like enhancer of split MRP-L46 PF11788.3 CCC66635.1 - 1e-33 116.2 0.0 1.7e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 SPG48 PF14764.1 CCC66635.1 - 0.14 10.6 0.1 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 AP-5 complex subunit, vesicle trafficking RRM_1 PF00076.17 CCC66636.1 - 8e-06 25.4 0.0 1.7e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC66636.1 - 4.1e-05 23.4 0.0 0.00028 20.7 0.0 2.3 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CTK3 PF12243.3 CCC66636.1 - 0.0081 15.7 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 4_1_CTD PF05902.8 CCC66636.1 - 0.043 13.8 0.2 0.45 10.5 0.0 2.3 2 0 0 2 2 2 0 4.1 protein C-terminal domain (CTD) Spo7_2_N PF15407.1 CCC66636.1 - 0.054 12.9 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 Sporulation protein family 7 OS-D PF03392.8 CCC66636.1 - 0.054 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D CTD_bind PF04818.8 CCC66636.1 - 0.077 13.2 0.0 0.24 11.6 0.0 1.8 1 0 0 1 1 1 0 RNA polymerase II-binding domain. RRM_5 PF13893.1 CCC66636.1 - 0.089 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_23 PF13476.1 CCC66637.1 - 1.4e-22 80.9 24.8 1.4e-22 80.9 17.2 9.2 2 1 3 5 5 5 1 AAA domain Rad50_zn_hook PF04423.9 CCC66637.1 - 7.2e-14 50.9 2.1 7.2e-14 50.9 1.4 5.5 5 0 0 5 5 5 1 Rad50 zinc hook motif SbcCD_C PF13558.1 CCC66637.1 - 2.1e-11 43.5 0.0 6.5e-11 42.0 0.0 1.9 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 CCC66637.1 - 9.2e-09 34.3 143.4 8.8e-05 21.1 0.1 7.0 3 1 3 6 6 6 3 AAA domain SMC_N PF02463.14 CCC66637.1 - 1.6e-07 30.8 0.1 1.6e-07 30.8 0.1 3.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCC66637.1 - 0.00034 20.0 0.0 0.00081 18.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CCC66637.1 - 0.00043 20.3 0.0 0.00043 20.3 0.0 6.1 3 2 1 4 4 4 2 AAA domain ABC_tran PF00005.22 CCC66637.1 - 0.011 16.0 0.1 0.011 16.0 0.1 8.3 3 2 2 5 5 5 0 ABC transporter AAA_19 PF13245.1 CCC66637.1 - 0.11 12.3 0.1 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain WEMBL PF05701.6 CCC66637.1 - 9.5 4.5 123.8 0.083 11.3 17.2 5.3 3 2 2 5 5 5 0 Weak chloroplast movement under blue light FGGY_N PF00370.16 CCC66638.1 - 0.0012 18.2 0.2 0.0088 15.3 0.1 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain RNA_pol_I_A49 PF06870.7 CCC66639.1 - 6e-131 436.5 4.4 6.7e-131 436.3 3.1 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor tRNA-synt_1e PF01406.14 CCC66640.1 - 7.7e-139 461.9 1.2 7.7e-139 461.9 0.8 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 CCC66640.1 - 3.3e-06 26.0 11.6 1.2e-05 24.1 0.2 3.0 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CCC66640.1 - 7e-05 21.0 0.0 7e-05 21.0 0.0 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) NAP PF00956.13 CCC66641.1 - 1.2e-20 73.6 6.5 1.9e-20 73.0 4.5 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Cir_N PF10197.4 CCC66642.1 - 4.9e-13 48.8 12.6 4.9e-13 48.8 8.7 2.8 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.3 CCC66642.1 - 1.6e-12 47.7 11.7 1.6e-12 47.7 8.1 2.3 1 1 1 2 2 2 1 Pre-mRNA splicing factor SUI1 PF01253.17 CCC66643.1 - 1e-27 95.7 1.1 1.2e-27 95.4 0.8 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 Yqai PF09466.5 CCC66643.1 - 0.061 13.3 0.1 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein Yqai ANTH PF07651.11 CCC66644.1 - 1.2e-71 240.6 0.0 1.2e-71 240.6 0.0 3.5 3 1 1 4 4 4 1 ANTH domain I_LWEQ PF01608.12 CCC66644.1 - 4.3e-57 192.3 7.3 4.3e-57 192.3 5.1 5.4 3 2 2 6 6 6 2 I/LWEQ domain ENTH PF01417.15 CCC66644.1 - 7.8e-07 29.0 0.1 7.8e-07 29.0 0.1 2.8 3 1 0 3 3 3 1 ENTH domain ATP-grasp_4 PF13535.1 CCC66644.1 - 0.037 13.7 0.0 0.14 11.8 0.0 2.0 1 0 0 1 1 1 0 ATP-grasp domain Med15 PF09606.5 CCC66644.1 - 3.4 5.7 65.9 0.053 11.7 40.3 1.7 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal ATG_C PF09333.6 CCC66645.1 - 3.7e-29 100.7 0.1 9.7e-29 99.4 0.1 1.8 1 0 0 1 1 1 1 ATG C terminal domain ATG2_CAD PF13329.1 CCC66645.1 - 2.6e-28 98.5 4.6 1.1e-27 96.4 0.4 3.3 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif G6PD_C PF02781.11 CCC66646.1 - 6.3e-126 419.1 0.0 8.4e-126 418.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CCC66646.1 - 1.2e-63 214.6 0.0 1.9e-63 214.0 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Fe_hyd_lg_C PF02906.9 CCC66647.1 - 4.4e-60 203.3 0.0 6e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Peptidase_S8 PF00082.17 CCC66648.1 - 6.7e-58 196.0 3.9 1.2e-57 195.2 2.7 1.4 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 CCC66648.1 - 4.7e-26 90.3 0.5 1e-25 89.2 0.3 1.6 1 0 0 1 1 1 1 Proprotein convertase P-domain DUF1049 PF06305.6 CCC66648.1 - 0.046 13.2 0.3 0.11 12.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF4233 PF14017.1 CCC66648.1 - 0.37 10.7 0.9 0.65 9.9 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) Ytp1 PF10355.4 CCC66649.1 - 5.3e-79 265.2 16.9 8.3e-79 264.5 11.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) Ninjurin PF04923.7 CCC66649.1 - 0.55 9.9 3.0 0.95 9.2 0.0 2.7 2 1 0 2 2 2 0 Ninjurin Med16 PF11635.3 CCC66650.1 - 2.6e-192 640.7 13.8 3.1e-192 640.4 9.6 1.0 1 0 0 1 1 1 1 Mediator complex subunit 16 Cation_efflux PF01545.16 CCC66651.1 - 8.8e-44 149.6 5.9 1.1e-43 149.3 4.1 1.1 1 0 0 1 1 1 1 Cation efflux family HR1 PF02185.11 CCC66651.1 - 0.077 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Hr1 repeat UPF0061 PF02696.9 CCC66653.1 - 1.7e-151 504.8 0.3 1.9e-151 504.6 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Spore_GerAC PF05504.6 CCC66653.1 - 0.1 12.3 2.3 1.2 8.9 0.3 2.4 2 0 0 2 2 2 0 Spore germination B3/ GerAC like, C-terminal TRP PF06011.7 CCC66654.1 - 4.3e-151 503.4 33.6 4.3e-151 503.4 23.3 1.4 2 0 0 2 2 2 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCC66654.1 - 1.2e-43 148.5 0.2 2e-43 147.8 0.1 1.4 1 0 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 CCC66654.1 - 0.017 15.3 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 ML domain Ribosomal_L1 PF00687.16 CCC66655.1 - 1.1e-44 152.3 1.8 1.4e-44 152.0 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Cyclin PF08613.6 CCC66656.1 - 4e-15 56.5 0.1 8.2e-15 55.4 0.1 1.7 1 0 0 1 1 1 1 Cyclin Arf PF00025.16 CCC66657.1 - 1.7e-49 167.3 0.0 1.9e-49 167.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CCC66657.1 - 1.7e-06 26.9 0.0 3.2e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 CCC66657.1 - 5.3e-06 26.9 0.0 7.7e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CCC66657.1 - 1.7e-05 24.3 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCC66657.1 - 0.013 14.6 0.0 0.017 14.3 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CCC66657.1 - 0.017 14.5 0.0 0.018 14.4 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF663 PF04950.7 CCC66658.1 - 6.9e-108 360.1 0.1 6.9e-108 360.1 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CCC66658.1 - 3.5e-29 100.1 0.0 9.7e-29 98.7 0.0 1.8 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 CCC66658.1 - 1.4e-07 31.1 0.0 3.9e-05 23.1 0.0 2.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA PF00004.24 CCC66658.1 - 7.9e-06 26.0 0.0 2.1e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 CCC66658.1 - 0.00012 21.7 0.1 0.00036 20.2 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CCC66658.1 - 0.00014 21.7 0.0 0.00058 19.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC66658.1 - 0.00016 21.7 0.0 0.0005 20.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CCC66658.1 - 0.00026 21.8 0.0 0.00026 21.8 0.0 4.2 3 2 0 3 3 3 1 AAA domain AAA_19 PF13245.1 CCC66658.1 - 0.0003 20.4 0.0 0.00095 18.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 CCC66658.1 - 0.00089 19.4 0.0 0.0032 17.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCC66658.1 - 0.0042 17.3 0.0 0.0042 17.3 0.0 4.6 4 1 0 4 4 3 1 AAA domain RNA_helicase PF00910.17 CCC66658.1 - 0.0045 17.1 0.0 0.014 15.5 0.0 1.9 1 0 0 1 1 1 1 RNA helicase NACHT PF05729.7 CCC66658.1 - 0.006 16.2 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_5 PF07728.9 CCC66658.1 - 0.011 15.4 0.0 0.027 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CCC66658.1 - 0.013 14.9 0.0 0.037 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 CCC66658.1 - 0.013 16.0 0.0 0.013 16.0 0.0 3.1 3 0 0 3 3 2 0 Miro-like protein MMR_HSR1 PF01926.18 CCC66658.1 - 0.014 15.3 0.1 0.072 13.0 0.0 2.3 2 0 0 2 2 2 0 50S ribosome-binding GTPase cobW PF02492.14 CCC66658.1 - 0.014 14.8 0.1 0.031 13.7 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 CCC66658.1 - 0.016 14.9 0.4 0.036 13.7 0.3 1.6 1 0 0 1 1 1 0 NTPase ABC_tran PF00005.22 CCC66658.1 - 0.016 15.5 1.8 0.036 14.3 0.0 2.6 2 0 0 2 2 1 0 ABC transporter AAA_11 PF13086.1 CCC66658.1 - 0.035 13.6 0.0 0.035 13.6 0.0 3.6 3 1 0 3 3 2 0 AAA domain PduV-EutP PF10662.4 CCC66658.1 - 0.099 12.1 0.0 14 5.2 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation WAC_Acf1_DNA_bd PF10537.4 CCC66659.1 - 1.4e-29 102.2 0.5 7.4e-29 99.9 0.3 2.4 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CCC66659.1 - 2.4e-15 56.0 0.1 2.6e-13 49.5 0.1 2.7 2 0 0 2 2 2 1 DDT domain WHIM2 PF15613.1 CCC66659.1 - 2.9e-07 30.1 1.5 1.3e-06 28.0 1.0 2.2 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 Ubiq_cyt_C_chap PF03981.7 CCC66660.1 - 3.6e-42 143.5 1.2 6e-42 142.8 0.8 1.3 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone HK PF02110.10 CCC66661.1 - 1.4e-85 286.4 1.5 2e-85 285.8 1.1 1.2 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 CCC66661.1 - 7.7e-58 194.5 0.0 1.4e-57 193.6 0.0 1.5 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI NMO PF03060.10 CCC66661.1 - 0.0021 17.2 0.0 0.0037 16.4 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Phos_pyr_kin PF08543.7 CCC66661.1 - 0.12 11.5 1.1 0.35 10.0 0.0 2.1 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase LRR_9 PF14580.1 CCC66662.1 - 3.6e-12 46.2 0.6 5.6e-12 45.5 0.5 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CCC66662.1 - 8.7e-11 41.2 17.3 3.3e-06 26.6 0.8 4.4 3 2 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCC66662.1 - 0.0068 16.2 16.3 3.1 8.1 1.1 5.5 3 2 2 5 5 5 4 Leucine Rich Repeat LRR_6 PF13516.1 CCC66662.1 - 0.014 15.4 13.0 6 7.2 0.6 5.4 4 1 1 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.1 CCC66662.1 - 0.32 10.7 15.7 0.056 13.1 3.4 3.4 2 1 3 5 5 5 0 Leucine rich repeat PseudoU_synth_1 PF01416.15 CCC66663.1 - 7.4e-23 80.9 0.1 4.1e-10 40.0 0.0 2.8 3 0 0 3 3 3 2 tRNA pseudouridine synthase DUF2344 PF10105.4 CCC66663.1 - 0.043 13.3 0.0 0.24 10.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) UPF0113 PF03657.8 CCC66664.1 - 6.3e-13 48.6 0.0 8.1e-13 48.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 CCC66664.1 - 0.029 14.4 0.0 0.06 13.4 0.0 1.6 1 1 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis PUA PF01472.15 CCC66664.1 - 0.098 12.3 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 PUA domain SRP72 PF08492.7 CCC66665.1 - 1.2e-09 38.3 8.3 1.2e-09 38.3 5.8 2.5 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_12 PF13424.1 CCC66665.1 - 8e-06 25.7 11.3 1.3e-05 25.0 0.6 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCC66665.1 - 9.6e-06 25.8 6.2 0.023 15.0 0.3 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCC66665.1 - 0.00022 20.8 8.8 0.0015 18.1 0.3 3.8 4 0 0 4 4 4 1 TPR repeat TPR_2 PF07719.12 CCC66665.1 - 0.0011 18.6 16.7 0.075 12.9 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CCC66665.1 - 0.0033 17.5 16.4 0.28 11.3 0.7 4.8 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCC66665.1 - 0.0036 17.6 4.7 0.43 11.1 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCC66665.1 - 0.0057 17.1 0.3 72 4.4 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Phage_min_tail PF05939.8 CCC66665.1 - 0.061 13.2 0.4 0.19 11.7 0.2 1.9 2 0 0 2 2 1 0 Phage minor tail protein TPR_7 PF13176.1 CCC66665.1 - 0.21 11.4 5.4 3.6 7.6 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCC66665.1 - 0.35 10.7 6.8 14 5.7 0.1 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 CCC66665.1 - 0.36 10.7 0.0 0.36 10.7 0.0 3.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.23 CCC66665.1 - 2.2 7.9 13.0 2.1 8.0 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat SET PF00856.23 CCC66666.1 - 0.0099 16.1 0.1 0.032 14.5 0.1 1.9 1 0 0 1 1 1 1 SET domain Radical_SAM PF04055.16 CCC66667.1 - 9.2e-23 81.2 0.0 1.7e-22 80.3 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Wyosine_form PF08608.7 CCC66667.1 - 1.5e-22 79.4 0.0 5.1e-22 77.7 0.0 2.0 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 CCC66667.1 - 2.1e-13 50.4 0.0 4.6e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin GDPD PF03009.12 CCC66668.1 - 8.3e-33 113.9 0.0 2.4e-32 112.4 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 CCC66668.1 - 0.07 13.3 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family Pkinase PF00069.20 CCC66669.1 - 7.6e-37 126.8 0.0 1.3e-36 126.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC66669.1 - 7.1e-11 41.6 0.0 1.2e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 CCC66670.1 - 6.6e-69 231.9 0.0 7.8e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC66670.1 - 2.5e-41 141.4 0.0 3.3e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC66670.1 - 1.9e-05 23.7 0.0 7.1e-05 21.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 CCC66670.1 - 0.063 12.6 0.2 0.17 11.2 0.1 1.8 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CCC66670.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCC66670.1 - 0.095 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 AFT PF08731.6 CCC66671.1 - 1e-35 122.3 5.9 1e-35 122.3 4.1 3.7 3 1 0 3 3 3 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 CCC66671.1 - 7.4e-05 22.2 0.1 0.029 13.9 0.0 2.6 2 0 0 2 2 2 2 MuDR family transposase FAR1 PF03101.10 CCC66671.1 - 0.0052 17.2 0.3 0.0052 17.2 0.2 2.0 2 0 0 2 2 2 1 FAR1 DNA-binding domain Lectin_C PF00059.16 CCC66672.1 - 0.17 12.5 5.7 0.21 12.2 0.0 3.4 3 1 1 4 4 4 0 Lectin C-type domain DUF1771 PF08590.5 CCC66673.1 - 4.9e-17 61.6 6.1 8.1e-17 60.9 4.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 CCC66673.1 - 1e-13 51.2 0.2 2.3e-13 50.1 0.0 1.6 2 0 0 2 2 2 1 Smr domain DUF1798 PF08807.5 CCC66673.1 - 0.0012 18.5 0.5 0.0043 16.7 0.1 2.0 1 1 1 2 2 2 1 Bacterial domain of unknown function (DUF1798) DUF3527 PF12043.3 CCC66673.1 - 0.083 12.4 1.3 0.11 12.0 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3527) cwf18 PF08315.7 CCC66673.1 - 0.1 13.0 1.9 0.17 12.3 1.3 1.3 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Rogdi_lz PF10259.4 CCC66674.1 - 0.063 12.3 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein TLD PF07534.11 CCC66675.1 - 6.3e-28 97.5 0.1 6.9e-27 94.1 0.0 2.1 1 1 0 1 1 1 1 TLD Adaptin_N PF01602.15 CCC66676.1 - 1.2e-113 380.2 17.7 1.7e-113 379.7 12.3 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCC66676.1 - 5.4e-09 36.1 0.5 5.4e-09 36.1 0.3 3.7 2 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCC66676.1 - 7.1e-08 32.6 0.0 0.31 11.3 0.0 5.3 2 2 2 4 4 4 2 HEAT repeats HEAT PF02985.17 CCC66676.1 - 9.2e-08 31.5 1.2 8.7 6.7 0.0 7.1 7 1 0 7 7 7 2 HEAT repeat Nipped-B_C PF12830.2 CCC66676.1 - 0.029 13.9 0.5 16 5.1 0.0 3.7 2 2 1 3 3 3 0 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.1 CCC66676.1 - 0.044 14.2 0.4 7.3 7.2 0.0 4.8 7 2 0 7 7 7 0 HEAT-like repeat DUF4604 PF15377.1 CCC66676.1 - 0.052 13.7 11.0 0.088 13.0 7.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) TENA_THI-4 PF03070.11 CCC66677.1 - 8.5e-13 48.5 1.0 1.2e-12 48.0 0.7 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family T4_Gp59_N PF08993.5 CCC66677.1 - 0.069 13.1 0.9 0.14 12.1 0.6 1.6 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase Dynamin_M PF01031.15 CCC66678.1 - 2.9e-109 364.4 0.3 5e-109 363.6 0.2 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 CCC66678.1 - 5.8e-54 182.4 0.0 5.8e-54 182.4 0.0 3.0 2 1 0 2 2 2 1 Dynamin family GED PF02212.13 CCC66678.1 - 1.7e-28 98.3 4.5 2.5e-28 97.8 2.1 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCC66678.1 - 0.00097 19.0 0.2 0.022 14.6 0.2 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCC66678.1 - 0.015 15.7 0.0 0.051 14.0 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 CCC66678.1 - 0.085 12.5 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Fasciclin PF02469.17 CCC66679.1 - 4.6e-18 65.4 5.6 0.00037 20.4 0.0 5.9 5 1 0 5 5 5 5 Fasciclin domain Rop-like PF05082.8 CCC66679.1 - 0.19 11.2 0.1 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 Rop-like dCMP_cyt_deam_1 PF00383.17 CCC66680.1 - 1.2e-22 79.4 0.1 1.7e-22 78.9 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CCC66680.1 - 0.00062 19.6 0.2 0.0022 17.8 0.1 1.9 1 1 0 1 1 1 1 Bd3614-like deaminase HSP70 PF00012.15 CCC66681.1 - 1e-265 882.4 13.8 1.1e-265 882.2 9.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCC66681.1 - 9.6e-20 70.4 2.1 2.1e-18 65.9 0.3 2.1 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 CCC66681.1 - 0.00016 20.8 1.6 0.028 13.5 0.0 3.2 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 CCC66681.1 - 0.0052 16.1 0.1 0.1 11.8 0.1 2.4 1 1 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_C PF02782.11 CCC66681.1 - 0.067 12.8 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 CCC66681.1 - 0.2 11.4 7.3 0.16 11.8 0.5 3.2 2 2 0 2 2 2 0 Cell division protein FtsA YbaB_DNA_bd PF02575.11 CCC66681.1 - 6.6 6.7 10.3 4.3 7.2 0.3 3.5 3 1 0 3 3 3 0 YbaB/EbfC DNA-binding family RRF PF01765.14 CCC66682.1 - 9e-35 119.5 6.3 9e-35 119.5 4.4 1.4 2 0 0 2 2 2 1 Ribosome recycling factor NPV_P10 PF05531.7 CCC66682.1 - 0.057 13.6 1.3 0.17 12.1 0.9 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.17 CCC66682.1 - 0.17 11.9 7.7 0.93 9.5 2.0 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NYD-SP28 PF14772.1 CCC66682.1 - 0.21 11.7 5.7 0.051 13.6 1.2 1.9 2 0 0 2 2 2 0 Sperm tail FliD_C PF07195.7 CCC66682.1 - 0.24 10.6 9.7 0.84 8.8 6.4 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus ApoLp-III PF07464.6 CCC66682.1 - 0.72 9.8 9.6 5.6 6.9 0.3 2.3 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) PhaP_Bmeg PF09602.5 CCC66682.1 - 0.8 9.5 7.4 0.29 10.9 0.4 2.5 2 1 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) TMPIT PF07851.8 CCC66682.1 - 0.82 8.6 9.0 1.1 8.2 2.2 2.1 2 0 0 2 2 2 0 TMPIT-like protein HemX PF04375.9 CCC66682.1 - 1.1 7.7 5.6 6.3 5.2 0.2 2.1 2 0 0 2 2 2 0 HemX Aldedh PF00171.17 CCC66683.1 - 1.3e-119 399.5 0.0 1.5e-119 399.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family V-ATPase_G PF03179.10 CCC66684.1 - 4.3e-30 104.1 11.4 4.9e-30 103.9 7.9 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 CCC66684.1 - 0.046 13.5 12.9 0.13 12.0 8.9 1.7 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) CpeT PF06206.6 CCC66684.1 - 0.048 13.3 0.3 0.056 13.1 0.2 1.2 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) S_layer_C PF05124.7 CCC66684.1 - 0.13 11.8 5.5 0.16 11.6 3.8 1.2 1 0 0 1 1 1 0 S-layer like family, C-terminal region Neisseria_TspB PF05616.8 CCC66684.1 - 0.14 10.5 0.8 0.16 10.3 0.5 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein DUF3552 PF12072.3 CCC66684.1 - 0.18 10.9 15.8 0.22 10.6 4.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) vATP-synt_E PF01991.13 CCC66684.1 - 0.22 10.8 10.1 0.28 10.4 7.0 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit DUF2362 PF10154.4 CCC66684.1 - 0.34 9.5 5.6 0.36 9.4 3.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) GA PF01468.12 CCC66684.1 - 0.97 9.6 11.8 0.11 12.7 4.6 2.2 2 1 0 2 2 2 0 GA module DUF2681 PF10883.3 CCC66684.1 - 6.1 7.1 8.2 2.7 8.2 3.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Med20 PF08612.6 CCC66685.1 - 6.2e-30 104.0 0.0 7.5e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex LSM PF01423.17 CCC66685.1 - 0.093 12.2 0.2 0.24 10.9 0.1 1.9 1 1 0 1 1 1 0 LSM domain FAD_binding_1 PF00667.15 CCC66686.1 - 2.6e-64 216.6 0.3 5e-64 215.7 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 CCC66686.1 - 2.3e-28 99.0 0.2 4.5e-28 98.0 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCC66686.1 - 6.4e-22 78.1 0.0 2.1e-21 76.5 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 CCC66686.1 - 0.058 13.3 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Flavodoxin domain HAD_2 PF13419.1 CCC66687.1 - 1.5e-14 54.5 0.0 2.3e-14 53.9 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCC66687.1 - 1.4e-07 31.1 0.1 2.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CCC66687.1 - 0.00041 20.5 0.0 0.00054 20.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC66687.1 - 0.00042 20.7 0.1 0.016 15.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCC66688.1 - 2.2e-14 54.0 0.0 2.7e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC66688.1 - 1.5e-05 25.5 0.0 0.00043 20.7 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCC66688.1 - 5.4e-05 22.8 0.1 9.5e-05 22.0 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CCC66688.1 - 0.00016 21.9 0.0 0.00023 21.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RabGAP-TBC PF00566.13 CCC66689.1 - 2e-15 56.8 1.5 2e-15 56.8 1.1 2.3 1 1 1 2 2 2 1 Rab-GTPase-TBC domain Fe-S_biosyn PF01521.15 CCC66689.1 - 0.058 13.3 0.1 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 Iron-sulphur cluster biosynthesis LRR_6 PF13516.1 CCC66690.1 - 0.059 13.4 3.0 11 6.5 0.0 4.6 4 0 0 4 4 4 0 Leucine Rich repeat Nsp1_C PF05064.8 CCC66691.1 - 1.7e-37 127.6 6.0 1.7e-37 127.6 4.1 2.1 1 1 1 2 2 2 1 Nsp1-like C-terminal region Muted PF14942.1 CCC66691.1 - 0.12 12.2 2.1 0.17 11.7 1.1 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Laminin_II PF06009.7 CCC66691.1 - 2.4 7.9 14.4 1.9 8.2 5.6 2.7 1 1 0 2 2 2 0 Laminin Domain II DUF3414 PF11894.3 CCC66692.1 - 0 1426.4 67.6 0 1426.2 46.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Ppx-GppA PF02541.11 CCC66692.1 - 0.021 14.0 0.1 0.081 12.1 0.0 2.0 2 0 0 2 2 2 0 Ppx/GppA phosphatase family AA_kinase PF00696.23 CCC66693.1 - 1.1e-38 133.1 0.7 2e-38 132.3 0.5 1.4 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CCC66693.1 - 2.5e-12 46.3 0.0 5.7e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 PUA domain DUF1930 PF09122.5 CCC66693.1 - 0.0057 16.4 0.4 0.038 13.7 0.0 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1930) Nucleotid_trans PF03407.11 CCC66693.1 - 0.11 12.2 0.1 0.23 11.1 0.0 1.5 2 0 0 2 2 2 0 Nucleotide-diphospho-sugar transferase PIH1 PF08190.7 CCC66694.1 - 1.4e-32 113.4 1.0 2.2e-32 112.8 0.6 1.3 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 FA_hydroxylase PF04116.8 CCC66695.1 - 1.9e-16 60.4 6.2 1.9e-16 60.4 4.3 2.1 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Sec23_trunk PF04811.10 CCC66696.1 - 4e-14 52.5 0.1 5.2e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCC66696.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Aldedh PF00171.17 CCC66697.1 - 3.6e-95 319.0 0.0 4.2e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DEAD PF00270.24 CCC66698.1 - 6.6e-44 149.3 0.0 2.6e-43 147.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CCC66698.1 - 2.1e-25 88.0 0.1 4.6e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CCC66698.1 - 7.8e-22 76.9 0.0 1.7e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 CCC66698.1 - 0.00056 19.9 0.1 0.00056 19.9 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain HORMA PF02301.13 CCC66699.1 - 2.7e-42 144.6 0.0 3e-42 144.4 0.0 1.0 1 0 0 1 1 1 1 HORMA domain CBF PF03914.12 CCC66700.1 - 3.6e-35 120.8 0.2 3.6e-35 120.8 0.1 3.1 2 1 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 CCC66700.1 - 1.4e-34 118.1 0.7 1.4e-34 118.1 0.5 3.1 2 1 1 3 3 3 1 Nucleolar complex-associated protein Candida_ALS_N PF11766.3 CCC66701.1 - 2.5e-67 226.3 4.1 2.5e-67 226.3 2.8 2.9 2 1 0 3 3 3 1 Cell-wall agglutinin N-terminal ligand-sugar binding Flocculin PF00624.13 CCC66701.1 - 1.1e-36 124.3 133.3 4e-11 42.5 18.0 10.2 9 2 1 10 10 10 4 Flocculin repeat DUF2318 PF10080.4 CCC66701.1 - 0.026 14.2 0.0 0.49 10.1 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) CMS1 PF14617.1 CCC66702.1 - 1.1e-16 60.6 14.7 2.6e-12 46.3 4.3 3.0 1 1 2 3 3 3 2 U3-containing 90S pre-ribosomal complex subunit VitD-bind_III PF09164.5 CCC66702.1 - 0.02 14.5 0.1 0.12 11.9 0.0 2.2 1 1 1 2 2 2 0 Vitamin D binding protein, domain III RED_C PF07807.6 CCC66702.1 - 0.3 11.2 6.5 5.2 7.2 0.2 2.4 2 0 0 2 2 2 0 RED-like protein C-terminal region SMC_Nse1 PF07574.8 CCC66703.1 - 2.6e-46 157.8 0.3 3.1e-46 157.5 0.2 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 CCC66703.1 - 1.2e-11 44.3 11.3 2.4e-11 43.4 7.9 1.5 1 0 0 1 1 1 1 RING-like domain SNF2_assoc PF08455.5 CCC66703.1 - 0.045 12.3 0.0 0.071 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated Ribosomal_L24e PF01246.15 CCC66704.1 - 4.5e-29 100.1 1.9 4.5e-29 100.1 1.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L24e zf-FCS PF06467.9 CCC66704.1 - 0.47 10.1 4.1 0.86 9.2 2.8 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif AAA_23 PF13476.1 CCC66704.1 - 2.9 8.1 10.2 3.4 7.9 7.1 1.2 1 0 0 1 1 1 0 AAA domain DUF2059 PF09832.4 CCC66705.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2059) SEP PF08059.8 CCC66705.1 - 0.074 13.3 0.1 12 6.3 0.0 3.2 3 0 0 3 3 3 0 SEP domain Proteasome PF00227.21 CCC66706.1 - 1.4e-46 158.2 1.4 1.6e-46 158.0 1.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Sfi1 PF08457.5 CCC66707.1 - 1.1e-23 83.5 75.3 2e-19 69.4 32.8 2.9 1 1 2 3 3 3 3 Sfi1 spindle body protein Sfi1_C PF10638.4 CCC66707.1 - 1.4e-21 76.9 4.3 7.1e-21 74.6 2.5 2.6 2 0 0 2 2 2 1 Spindle body associated protein C-terminus Ribophorin_I PF04597.9 CCC66708.1 - 7.9e-124 413.4 3.6 9e-124 413.2 2.5 1.0 1 0 0 1 1 1 1 Ribophorin I ORC3_N PF07034.6 CCC66709.1 - 0.00021 20.4 0.8 0.00082 18.4 0.3 1.9 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus Sir1 PF11603.3 CCC66709.1 - 0.14 12.3 2.4 0.68 10.0 0.2 2.9 3 0 0 3 3 3 0 Regulatory protein Sir1 DUF221 PF02714.10 CCC66710.1 - 4.6e-85 285.3 21.1 4.6e-85 285.3 14.7 2.4 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCC66710.1 - 3.6e-29 101.3 2.1 3.6e-29 101.3 1.5 2.5 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF2236 PF09995.4 CCC66710.1 - 0.079 12.2 0.0 0.18 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) DUF2404 PF10296.4 CCC66711.1 - 0.00024 21.1 0.2 0.00087 19.3 0.1 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) DEAD PF00270.24 CCC66713.1 - 4.2e-46 156.5 0.3 1.5e-45 154.7 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC66713.1 - 9.8e-27 92.6 0.0 2.6e-26 91.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCC66713.1 - 0.11 12.5 0.7 0.29 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain COX17 PF05051.8 CCC66714.1 - 1.3e-20 73.1 6.7 1.3e-20 73.1 4.6 1.4 2 0 0 2 2 2 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 CCC66714.1 - 0.017 14.8 10.5 0.079 12.7 0.1 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CCC66714.1 - 0.029 14.2 2.6 0.036 13.9 0.9 1.9 2 1 0 2 2 2 0 CHCH domain DPPIV_N PF00930.16 CCC66715.1 - 3.7e-100 334.9 3.3 5.6e-100 334.3 2.3 1.3 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CCC66715.1 - 4.4e-50 169.8 2.6 6.8e-50 169.2 1.8 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCC66715.1 - 2e-09 37.3 0.0 4.9e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCC66715.1 - 0.00026 20.9 0.0 0.005 16.7 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 CCC66715.1 - 0.034 13.7 0.0 0.07 12.6 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 CCC66715.1 - 0.044 13.2 0.2 7 6.0 0.1 2.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 CCC66715.1 - 0.15 11.3 0.1 1.9 7.7 0.1 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Med6 PF04934.9 CCC66716.1 - 4.4e-52 175.3 0.4 7.4e-52 174.6 0.3 1.4 1 0 0 1 1 1 1 MED6 mediator sub complex component IGR PF09597.5 CCC66717.1 - 6.9e-23 80.3 0.2 1.5e-22 79.2 0.0 1.6 2 0 0 2 2 2 1 IGR protein motif RNase_H2-Ydr279 PF09468.5 CCC66718.1 - 0.032 13.4 0.1 0.039 13.1 0.1 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) PBD PF00786.23 CCC66719.1 - 0.00074 19.8 0.3 0.0021 18.4 0.2 2.0 1 1 0 1 1 1 1 P21-Rho-binding domain CdCA1 PF10563.4 CCC66719.1 - 0.099 12.1 0.1 0.23 10.9 0.0 1.7 1 1 0 1 1 1 0 Cadmium carbonic anhydrase repeat Fungal_trans PF04082.13 CCC66721.1 - 3.5e-27 94.9 9.8 1.7e-26 92.7 5.4 2.3 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC66721.1 - 7.2e-09 35.4 17.7 1.8e-08 34.1 12.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Proteasome PF00227.21 CCC66722.1 - 1.5e-46 158.1 0.0 2.2e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCC66722.1 - 1.9e-15 55.8 0.1 3.4e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF962 PF06127.6 CCC66723.1 - 1.6e-24 85.5 2.4 4.7e-24 84.1 1.7 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Aconitase PF00330.15 CCC66724.1 - 1.6e-192 640.1 0.1 1.9e-192 639.8 0.1 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCC66724.1 - 4.5e-46 156.1 0.0 8.8e-46 155.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain ATE_C PF04377.10 CCC66726.1 - 9.1e-43 145.3 1.1 2.3e-42 144.0 0.8 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 CCC66726.1 - 2.5e-23 81.6 2.9 3.4e-23 81.2 0.8 2.0 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus HSCB_C PF07743.8 CCC66727.1 - 7.4e-18 64.7 2.7 7.4e-18 64.7 1.9 2.1 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 CCC66727.1 - 1.4e-13 50.3 0.2 3.4e-13 49.0 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain Pterin_4a PF01329.14 CCC66727.1 - 0.13 12.0 4.4 2.7 7.8 0.1 3.1 2 1 1 3 3 3 0 Pterin 4 alpha carbinolamine dehydratase CK_II_beta PF01214.13 CCC66728.1 - 7.9e-73 243.8 0.1 1.1e-72 243.4 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF863 PF05904.6 CCC66728.1 - 0.086 11.1 0.4 0.12 10.6 0.3 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) CHD5 PF04420.9 CCC66729.1 - 1.1e-48 164.9 1.8 1.5e-48 164.5 1.3 1.1 1 0 0 1 1 1 1 CHD5-like protein Hom_end_hint PF05203.11 CCC66729.1 - 0.024 14.3 0.0 0.025 14.3 0.0 1.1 1 0 0 1 1 1 0 Hom_end-associated Hint Rsd_AlgQ PF04353.8 CCC66729.1 - 0.042 13.5 1.4 0.062 13.0 1.0 1.2 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ DUF2207 PF09972.4 CCC66729.1 - 0.4 9.2 6.7 0.6 8.6 4.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Kinetocho_Slk19 PF12709.2 CCC66729.1 - 9.8 6.3 13.5 0.94 9.5 2.6 2.3 1 1 1 2 2 2 0 Central kinetochore-associated STT3 PF02516.9 CCC66730.1 - 5.2e-136 454.4 52.9 3.3e-135 451.7 36.7 1.9 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit Hamartin PF04388.7 CCC66730.1 - 0.4 9.2 0.3 0.58 8.7 0.2 1.1 1 0 0 1 1 1 0 Hamartin protein FYVE PF01363.16 CCC66731.1 - 8.5e-16 57.6 7.7 1.8e-15 56.5 5.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger HypA PF01155.14 CCC66731.1 - 0.047 13.3 2.2 0.15 11.7 1.6 1.8 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Glyco_hydro_63 PF03200.11 CCC66734.1 - 1.4e-213 711.1 8.8 7e-213 708.8 6.1 1.7 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase GDE_C PF06202.9 CCC66734.1 - 0.0012 17.5 0.1 0.0021 16.8 0.1 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Macoilin PF09726.4 CCC66735.1 - 0.063 11.5 8.3 0.077 11.2 5.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Slu7 PF11708.3 CCC66735.1 - 0.1 12.3 1.9 0.16 11.7 1.3 1.2 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Ribosomal_L7Ae PF01248.21 CCC66736.1 - 1.9e-25 88.1 0.1 2.1e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ribosomal_L24e PF01246.15 CCC66737.1 - 2.8e-34 116.8 0.4 2.8e-34 116.8 0.3 2.2 2 1 0 2 2 2 1 Ribosomal protein L24e RR_TM4-6 PF06459.7 CCC66737.1 - 0.83 9.4 7.6 0.96 9.2 5.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.11 CCC66737.1 - 4.1 6.8 10.9 4.9 6.6 7.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TBPIP PF07106.8 CCC66739.1 - 3.5e-40 137.3 6.2 4.2e-40 137.0 4.3 1.1 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AKNA PF12443.3 CCC66739.1 - 0.022 14.7 0.3 0.06 13.3 0.0 1.8 1 1 1 2 2 2 0 AT-hook-containing transcription factor Seryl_tRNA_N PF02403.17 CCC66739.1 - 0.037 14.0 0.1 0.037 14.0 0.1 2.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CLASP_N PF12348.3 CCC66739.1 - 0.048 13.0 1.1 0.62 9.3 0.2 2.2 2 0 0 2 2 2 0 CLASP N terminal SusE PF14292.1 CCC66739.1 - 0.09 12.6 1.5 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 SusE outer membrane protein T4SS PF07996.6 CCC66739.1 - 0.14 11.9 2.4 11 5.7 0.1 2.4 2 1 0 2 2 2 0 Type IV secretion system proteins Lge1 PF11488.3 CCC66739.1 - 1.9 8.7 5.0 0.78 9.9 0.3 2.3 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 DUF904 PF06005.7 CCC66739.1 - 7.5 6.9 9.4 17 5.7 4.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF904) zf-H2C2_2 PF13465.1 CCC66740.1 - 3.8e-10 39.5 14.7 2.4e-06 27.5 2.7 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CCC66740.1 - 8e-07 29.0 14.5 0.0055 16.9 1.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC66740.1 - 0.00037 20.6 13.2 0.093 13.1 0.5 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCC66740.1 - 1 9.3 5.6 4.2 7.4 0.8 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Ecl1 PF12855.2 CCC66741.1 - 8e-15 53.8 3.2 1.8e-14 52.7 2.2 1.6 1 0 0 1 1 1 1 Life-span regulatory factor zf-FCS PF06467.9 CCC66741.1 - 0.049 13.2 0.8 0.12 12.0 0.6 1.7 1 1 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif SNARE PF05739.14 CCC66742.1 - 0.0011 18.5 5.1 0.0011 18.5 3.5 3.4 3 0 0 3 3 3 1 SNARE domain V-SNARE_C PF12352.3 CCC66742.1 - 0.027 14.5 8.5 0.39 10.8 0.2 3.2 4 0 0 4 4 4 0 Snare region anchored in the vesicle membrane C-terminus NUC153 PF08159.7 CCC66743.1 - 4.1e-13 48.6 4.0 9.3e-13 47.5 2.8 1.7 1 0 0 1 1 1 1 NUC153 domain Isochorismatase PF00857.15 CCC66745.1 - 4.9e-29 101.4 0.0 7.1e-29 100.9 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Ish1 PF10281.4 CCC66745.1 - 0.18 11.8 1.3 16 5.6 0.1 2.7 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein Gly_transf_sug PF04488.10 CCC66746.1 - 4.5e-12 46.2 0.0 1.3e-11 44.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Ras PF00071.17 CCC66747.1 - 5.8e-50 168.8 0.0 9.7e-50 168.1 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC66747.1 - 1e-17 64.7 1.7 1.8e-17 63.9 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 CCC66747.1 - 6.6e-08 32.1 0.0 6.6e-08 32.1 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CCC66747.1 - 1.1e-07 31.2 0.1 1.6e-07 30.7 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCC66747.1 - 0.0083 16.0 0.2 0.026 14.4 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Neur_chan_memb PF02932.11 CCC66747.1 - 8.3 6.2 10.3 11 5.8 7.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ALAD PF00490.16 CCC66748.1 - 3.8e-116 387.5 0.0 4.5e-116 387.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Pyridox_oxase_2 PF12766.2 CCC66749.1 - 6.9e-30 103.3 0.1 1.1e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Aminotran_3 PF00202.16 CCC66750.1 - 3.6e-83 279.2 0.0 4.3e-83 278.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III ATP-synt_F PF01990.12 CCC66751.1 - 3.1e-29 101.2 0.2 3.7e-29 100.9 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit Transcrip_reg PF01709.15 CCC66752.1 - 6.1e-55 185.8 4.7 7.3e-55 185.6 3.3 1.1 1 0 0 1 1 1 1 Transcriptional regulator Mid2 PF04478.7 CCC66753.1 - 9.2e-52 174.5 3.7 9.2e-52 174.5 2.5 2.6 1 1 2 3 3 3 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 CCC66753.1 - 0.064 12.5 0.0 0.23 10.8 0.0 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF2737 PF10930.3 CCC66754.1 - 0.046 13.3 0.0 0.39 10.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2737) HR1 PF02185.11 CCC66754.1 - 0.086 12.5 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Hr1 repeat MpPF26 PF07666.6 CCC66756.1 - 0.015 15.2 4.9 1 9.2 0.1 2.6 2 1 0 2 2 2 0 M penetrans paralogue family 26 AAA PF00004.24 CCC66757.1 - 1.4e-37 128.8 0.0 2.5e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CCC66757.1 - 3.4e-07 30.2 0.0 6.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC66757.1 - 5.7e-07 29.6 0.2 0.00021 21.3 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 CCC66757.1 - 2.2e-06 27.8 0.4 0.00013 22.1 0.0 2.7 2 1 1 3 3 2 1 AAA domain AAA_2 PF07724.9 CCC66757.1 - 2.2e-06 27.7 0.0 5.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CCC66757.1 - 2.8e-06 26.5 0.0 6.7e-06 25.3 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CCC66757.1 - 4.3e-06 26.5 0.2 9.2e-05 22.1 0.2 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CCC66757.1 - 4.8e-06 27.4 0.0 1.1e-05 26.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCC66757.1 - 5.4e-05 23.0 0.0 0.00015 21.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCC66757.1 - 6.1e-05 22.2 0.0 0.00011 21.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 CCC66757.1 - 0.00031 20.2 0.0 0.00063 19.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CCC66757.1 - 0.00043 19.5 0.3 0.0015 17.7 0.1 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 CCC66757.1 - 0.00044 20.2 0.0 0.00092 19.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 CCC66757.1 - 0.00052 20.3 0.0 0.0018 18.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 CCC66757.1 - 0.00088 19.4 0.0 0.0027 17.8 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.1 CCC66757.1 - 0.0014 18.2 0.0 0.0039 16.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 CCC66757.1 - 0.0014 18.0 0.6 0.017 14.4 0.1 2.3 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 CCC66757.1 - 0.0031 17.1 0.0 0.0087 15.7 0.0 1.7 1 0 0 1 1 1 1 NACHT domain Sigma54_activat PF00158.21 CCC66757.1 - 0.0042 16.5 0.0 0.014 14.9 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 CCC66757.1 - 0.0042 17.3 0.0 0.01 16.1 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 CCC66757.1 - 0.0062 16.0 0.3 1 8.7 0.0 2.5 1 1 1 2 2 2 1 AAA-like domain DUF815 PF05673.8 CCC66757.1 - 0.0069 15.3 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 CCC66757.1 - 0.0073 16.2 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 CCC66757.1 - 0.0079 15.8 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial dnaA protein Arch_ATPase PF01637.13 CCC66757.1 - 0.0088 15.7 0.0 0.066 12.9 0.0 2.2 1 1 1 2 2 2 1 Archaeal ATPase KAP_NTPase PF07693.9 CCC66757.1 - 0.014 14.3 0.1 0.52 9.2 0.0 2.3 1 1 1 2 2 2 0 KAP family P-loop domain Rad17 PF03215.10 CCC66757.1 - 0.015 14.0 0.0 0.03 13.0 0.0 1.4 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 CCC66757.1 - 0.016 14.8 0.0 0.034 13.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCC66757.1 - 0.024 14.3 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 CCC66757.1 - 0.026 13.2 0.1 0.05 12.3 0.0 1.4 1 1 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 CCC66757.1 - 0.026 14.1 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.12 CCC66757.1 - 0.036 12.9 0.0 0.066 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATP-synt_ab PF00006.20 CCC66757.1 - 0.045 13.2 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Viral_helicase1 PF01443.13 CCC66757.1 - 0.045 13.2 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase NB-ARC PF00931.17 CCC66757.1 - 0.057 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain SKI PF01202.17 CCC66757.1 - 0.071 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Shikimate kinase Guanylate_kin PF00625.16 CCC66757.1 - 0.11 11.9 0.0 1.4 8.3 0.0 2.7 4 0 0 4 4 3 0 Guanylate kinase PhoH PF02562.11 CCC66757.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein UPF0079 PF02367.12 CCC66757.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CPT PF07931.7 CCC66757.1 - 0.13 11.8 0.0 0.24 11.0 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_21 PF13304.1 CCC66757.1 - 0.21 11.5 2.7 15 5.4 0.2 2.9 2 1 1 3 3 3 0 AAA domain Evr1_Alr PF04777.8 CCC66758.1 - 1e-29 102.2 3.7 1.9e-29 101.4 2.6 1.4 1 0 0 1 1 1 1 Erv1 / Alr family Alba PF01918.16 CCC66759.1 - 4.9e-07 29.2 0.0 7.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Alba WND PF07861.6 CCC66759.1 - 0.03 13.3 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 WisP family N-Terminal Region Ribosomal_L10 PF00466.15 CCC66760.1 - 8.2e-26 89.8 0.2 1.5e-25 88.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 CCC66760.1 - 7e-19 68.0 6.2 7.7e-19 67.8 2.1 2.2 2 0 0 2 2 2 1 60s Acidic ribosomal protein Abhydrolase_6 PF12697.2 CCC66761.1 - 1.2e-28 100.5 0.0 1.6e-28 100.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC66761.1 - 2.8e-18 66.3 0.0 5.8e-18 65.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCC66761.1 - 1.6e-11 44.1 0.0 4.6e-11 42.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 CCC66761.1 - 2.6e-07 30.4 0.2 5.1e-07 29.4 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.3 CCC66761.1 - 0.0022 17.8 0.0 0.0046 16.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase DUF2305 PF10230.4 CCC66761.1 - 0.0032 16.9 0.2 0.0086 15.5 0.1 1.6 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF676 PF05057.9 CCC66761.1 - 0.016 14.5 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Thioesterase PF00975.15 CCC66761.1 - 0.11 12.7 0.0 0.27 11.4 0.0 1.6 2 0 0 2 2 2 0 Thioesterase domain Glucan_synthase PF02364.10 CCC66762.1 - 0 1446.8 0.0 0 1446.1 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCC66762.1 - 1.6e-39 134.4 2.2 1.8e-39 134.2 0.4 2.0 2 0 0 2 2 2 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SRP1_TIP1 PF00660.12 CCC66762.1 - 0.17 11.7 1.0 0.72 9.7 0.5 2.1 2 0 0 2 2 2 0 Seripauperin and TIP1 family TIM21 PF08294.6 CCC66763.1 - 3.3e-56 188.9 0.1 4.4e-56 188.5 0.1 1.2 1 0 0 1 1 1 1 TIM21 Secretin_N_2 PF07655.8 CCC66763.1 - 0.016 15.5 0.2 0.029 14.7 0.1 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain KOW PF00467.24 CCC66764.1 - 3.9e-05 23.1 0.5 3.9e-05 23.1 0.4 1.9 2 0 0 2 2 2 1 KOW motif His_Phos_1 PF00300.17 CCC66765.1 - 1.4e-10 41.4 0.0 2.8e-10 40.5 0.0 1.6 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 1) 6PF2K PF01591.13 CCC66765.1 - 7.3e-08 31.7 10.1 2.8e-05 23.3 0.7 3.0 2 1 1 3 3 3 2 6-phosphofructo-2-kinase Spore_YhaL PF14147.1 CCC66765.1 - 3.5 7.1 5.0 1.2 8.6 0.7 2.3 3 0 0 3 3 3 0 Sporulation protein YhaL PAP2 PF01569.16 CCC66767.1 - 2e-18 66.3 0.3 3.4e-18 65.5 0.1 1.4 1 1 0 1 1 1 1 PAP2 superfamily UbiA PF01040.13 CCC66767.1 - 0.0081 15.4 7.6 0.025 13.7 5.3 1.7 1 1 0 1 1 1 1 UbiA prenyltransferase family UPF0542 PF15086.1 CCC66767.1 - 0.011 15.4 0.3 0.03 14.0 0.2 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 Apidaecin PF00807.12 CCC66767.1 - 0.13 11.9 3.5 0.21 11.2 2.4 1.3 1 0 0 1 1 1 0 Apidaecin ACBP PF00887.14 CCC66768.1 - 4.3e-30 103.2 0.3 4.7e-30 103.1 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 CCC66768.1 - 0.016 15.3 0.1 0.37 10.9 0.0 2.0 1 1 1 2 2 2 0 FERM central domain DUF1413 PF07205.6 CCC66768.1 - 0.11 12.1 0.1 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) ORMDL PF04061.9 CCC66769.1 - 4.3e-58 194.6 7.2 5.4e-58 194.3 5.0 1.1 1 0 0 1 1 1 1 ORMDL family Pkinase PF00069.20 CCC66770.1 - 1e-73 247.7 0.0 1.3e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC66770.1 - 3.5e-34 118.0 0.0 6.5e-34 117.1 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC66770.1 - 6e-06 25.4 0.0 1.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCC66770.1 - 0.0056 15.7 0.1 0.026 13.5 0.1 1.9 1 1 1 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1160 PF06648.6 CCC66770.1 - 0.013 15.2 1.3 0.068 12.9 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) DUF2533 PF10752.4 CCC66771.1 - 0.11 12.8 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2533) DUF1035 PF06281.7 CCC66771.1 - 3.8 7.3 6.3 3 7.7 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) DUF2439 PF10382.4 CCC66772.1 - 1e-24 86.5 2.0 1e-24 86.5 1.4 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2439) DUF3502 PF12010.3 CCC66772.1 - 0.19 11.6 2.4 0.13 12.2 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) Transaldolase PF00923.14 CCC66773.1 - 5.6e-94 314.4 2.7 6.5e-94 314.2 1.9 1.0 1 0 0 1 1 1 1 Transaldolase zf-C2H2 PF00096.21 CCC66774.1 - 3.9e-08 33.1 15.5 0.012 15.9 0.2 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC66774.1 - 2.2e-06 27.5 19.8 0.089 13.1 0.3 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CCC66774.1 - 0.3 11.2 5.2 0.76 9.9 0.3 2.5 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Pkinase PF00069.20 CCC66776.1 - 7e-50 169.5 0.1 9.6e-50 169.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC66776.1 - 1.3e-26 93.1 0.0 1.9e-26 92.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC66776.1 - 1.6e-05 24.0 0.0 6.3e-05 22.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCC66776.1 - 0.00012 21.8 0.0 0.23 11.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CCC66776.1 - 0.0064 15.5 0.0 0.012 14.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 CCC66776.1 - 0.019 14.5 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Bromodomain PF00439.20 CCC66778.1 - 9.8e-27 92.7 6.3 8.3e-13 48.0 0.3 2.9 3 0 0 3 3 3 2 Bromodomain BAH PF01426.13 CCC66778.1 - 2.8e-24 85.1 0.1 7.9e-24 83.7 0.1 1.8 1 0 0 1 1 1 1 BAH domain PBP1_TM PF14812.1 CCC66778.1 - 5 7.5 13.8 1.9 8.8 3.7 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Folliculin PF11704.3 CCC66779.1 - 1.5e-49 167.8 0.1 2e-49 167.4 0.1 1.1 1 0 0 1 1 1 1 Vesicle coat protein involved in Golgi to plasma membrane transport DUF3181 PF11378.3 CCC66779.1 - 0.017 15.1 0.1 0.034 14.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) DUF2321 PF10083.4 CCC66779.1 - 0.031 13.7 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) EF-hand_7 PF13499.1 CCC66780.1 - 2e-08 34.2 7.5 0.00043 20.3 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 CCC66780.1 - 2.7e-08 32.5 0.4 0.19 11.1 0.0 4.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CCC66780.1 - 1.3e-07 30.9 1.6 0.007 16.1 0.0 4.2 3 1 1 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 CCC66780.1 - 2e-05 24.1 0.7 0.37 10.4 0.2 3.6 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CCC66780.1 - 0.19 11.1 1.4 31 4.1 0.0 3.7 4 0 0 4 4 4 0 EF hand Septin PF00735.13 CCC66781.1 - 1.6e-77 260.2 3.1 2.6e-77 259.6 2.1 1.3 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 CCC66781.1 - 5.1e-06 25.7 0.1 1.1e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CCC66781.1 - 0.00017 21.5 0.1 0.00044 20.1 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCC66781.1 - 0.00017 22.0 0.1 0.00057 20.3 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 CCC66781.1 - 0.00064 18.6 0.8 0.0019 17.0 0.0 2.1 2 1 1 3 3 3 1 Interferon-inducible GTPase (IIGP) Sigma54_activat PF00158.21 CCC66781.1 - 0.0024 17.3 0.1 0.024 14.1 0.0 2.3 2 1 0 2 2 2 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 CCC66781.1 - 0.0062 16.0 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family ABC_tran PF00005.22 CCC66781.1 - 0.0098 16.1 2.2 0.014 15.6 0.2 2.4 3 1 0 3 3 3 1 ABC transporter AAA_17 PF13207.1 CCC66781.1 - 0.012 16.3 1.8 0.7 10.7 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCC66781.1 - 0.019 14.4 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 CCC66781.1 - 0.044 13.2 0.1 0.092 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA-like domain Dynamin_N PF00350.18 CCC66781.1 - 0.057 13.2 2.1 0.067 12.9 0.1 2.1 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.17 CCC66781.1 - 0.071 13.2 0.3 0.34 11.0 0.0 2.3 3 0 0 3 3 3 0 RNA helicase ArgK PF03308.11 CCC66781.1 - 0.082 11.6 0.1 1.6 7.4 0.0 2.1 2 0 0 2 2 2 0 ArgK protein FA_hydroxylase PF04116.8 CCC66782.1 - 4.8e-16 59.1 20.1 4.8e-16 59.1 13.9 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GATase_5 PF13507.1 CCC66783.1 - 9.5e-101 336.0 0.0 1.4e-100 335.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 CCC66783.1 - 2e-45 154.4 0.2 6.7e-26 91.1 0.0 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 CCC66783.1 - 4.6e-23 81.2 0.1 2e-22 79.2 0.0 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain DUF4530 PF15039.1 CCC66783.1 - 0.082 12.8 0.1 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4530) DUF2462 PF09495.5 CCC66784.1 - 1.8e-19 70.2 10.2 1.8e-19 70.2 7.1 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2462) 60KD_IMP PF02096.15 CCC66785.1 - 8.1e-16 58.2 7.4 7.6e-15 55.1 5.1 2.1 1 1 0 1 1 1 1 60Kd inner membrane protein TilS_C PF11734.3 CCC66785.1 - 0.38 10.0 2.6 0.26 10.5 0.3 1.8 2 0 0 2 2 2 0 TilS substrate C-terminal domain Spt4 PF06093.8 CCC66786.1 - 3.8e-29 100.3 0.2 4.5e-29 100.1 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger zf-TFIIB PF13453.1 CCC66786.1 - 0.062 12.5 1.3 0.093 11.9 0.6 1.6 1 1 0 1 1 1 0 Transcription factor zinc-finger MFS_1 PF07690.11 CCC66787.1 - 5.7e-16 58.1 22.3 7.7e-16 57.7 14.3 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily 7TMR-DISM_7TM PF07695.6 CCC66787.1 - 0.0046 16.6 8.8 0.0046 16.6 6.1 3.1 3 2 1 4 4 4 1 7TM diverse intracellular signalling Ribosomal_S8 PF00410.14 CCC66788.1 - 6.6e-26 90.6 0.2 9e-26 90.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 zf-C2H2 PF00096.21 CCC66789.1 - 0.00031 20.9 12.9 0.066 13.5 2.7 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC66789.1 - 0.0059 16.8 5.8 0.0059 16.8 4.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC66789.1 - 0.0071 16.6 11.7 0.022 15.0 1.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger SR-25 PF10500.4 CCC66789.1 - 0.025 14.0 5.0 0.053 12.9 3.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Arrestin_C PF02752.17 CCC66790.1 - 7.2e-17 61.7 0.6 2.7e-16 59.9 0.1 2.1 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCC66790.1 - 5.7e-11 42.4 0.3 1.3e-07 31.5 0.0 2.4 1 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain CNH PF00780.17 CCC66791.1 - 5.2e-77 258.9 0.5 5.2e-77 258.9 0.3 1.9 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 CCC66791.1 - 9.5e-39 132.4 0.0 9.5e-39 132.4 0.0 3.9 4 1 0 5 5 5 1 Pleckstrin homology domain RhoGEF PF00621.15 CCC66791.1 - 3.7e-32 111.6 2.9 2.9e-31 108.7 0.0 2.8 2 0 0 2 2 2 1 RhoGEF domain DEP PF00610.16 CCC66791.1 - 8.5e-13 47.8 0.0 1.9e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) ELO PF01151.13 CCC66792.1 - 1.9e-60 204.3 25.2 2.4e-60 203.9 17.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family zf-BED PF02892.10 CCC66793.1 - 5.3e-05 22.8 0.1 0.00015 21.4 0.1 1.8 1 0 0 1 1 1 1 BED zinc finger zf-C2H2_6 PF13912.1 CCC66794.1 - 0.00035 20.3 8.1 0.0048 16.7 0.1 3.8 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CCC66794.1 - 0.00073 19.7 1.3 0.00073 19.7 0.9 5.0 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC66794.1 - 0.00076 19.6 17.6 0.0012 18.9 0.8 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCC66794.1 - 0.0019 18.3 2.2 0.0019 18.3 1.5 4.7 4 1 1 5 5 5 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCC66794.1 - 0.0098 16.0 3.4 0.27 11.4 0.0 3.2 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding Tox-GHH PF15636.1 CCC66794.1 - 0.097 12.3 0.1 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin Rad50_zn_hook PF04423.9 CCC66794.1 - 0.27 10.7 2.6 1 8.8 0.1 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Di19 PF05605.7 CCC66794.1 - 0.48 10.5 7.3 0.45 10.6 2.0 3.1 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_3 PF14369.1 CCC66794.1 - 2.4 8.2 4.6 1.7 8.7 0.2 2.8 3 0 0 3 3 3 0 zinc-finger KRE9 PF05390.6 CCC66795.1 - 4.1e-51 171.8 8.3 4.1e-51 171.8 5.8 2.0 2 0 0 2 2 2 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CCC66795.1 - 2.5e-14 53.5 3.2 2.5e-14 53.5 2.2 2.1 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family La PF05383.12 CCC66796.1 - 5e-23 80.6 1.0 9.4e-23 79.7 0.0 2.0 2 0 0 2 2 2 1 La domain RRM_6 PF14259.1 CCC66796.1 - 7.1e-08 32.3 0.1 1.8e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCC66796.1 - 5e-06 26.0 0.4 1.6e-05 24.4 0.2 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC66796.1 - 0.0041 16.9 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3662 PF12401.3 CCC66796.1 - 0.0081 16.3 0.1 0.11 12.6 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2662) Acyltransferase PF01553.16 CCC66797.1 - 7.8e-34 115.9 0.0 1.1e-33 115.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Aft1_HRR PF11787.3 CCC66798.1 - 0.54 11.3 4.1 24 6.0 2.9 2.5 1 1 0 1 1 1 0 Aft1 HRR domain MFS_1 PF07690.11 CCC66799.1 - 4.5e-17 61.8 16.0 4.7e-17 61.7 10.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily FA_hydroxylase PF04116.8 CCC66800.1 - 6.2e-16 58.8 20.6 6.2e-16 58.8 14.2 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FDC-SP PF15215.1 CCC66800.1 - 0.027 14.7 1.6 0.11 12.7 1.1 2.1 1 0 0 1 1 1 0 Follicular dendritic cell secreted peptide VirB3 PF05101.8 CCC66800.1 - 0.17 11.8 1.5 0.48 10.4 0.0 2.4 3 0 0 3 3 3 0 Type IV secretory pathway, VirB3-like protein NTP_transferase PF00483.18 CCC66801.1 - 6.5e-49 166.4 0.0 8.5e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CCC66801.1 - 2e-10 40.9 0.0 2.7e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 CCC66801.1 - 8.2e-10 37.7 6.1 1.1e-07 30.9 1.2 3.7 1 1 4 5 5 5 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CCC66801.1 - 0.0075 15.8 6.2 0.045 13.3 0.5 3.2 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 CCC66801.1 - 0.031 13.9 0.0 0.062 12.9 0.0 1.5 1 1 0 1 1 1 0 Cytidylyltransferase Ank_2 PF12796.2 CCC66802.1 - 6.2e-14 52.1 0.0 6.8e-06 26.3 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCC66802.1 - 5.7e-13 48.6 0.2 5.2e-07 29.6 0.2 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCC66802.1 - 3.9e-12 46.3 0.7 0.00011 22.6 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 CCC66802.1 - 3.2e-09 36.1 0.4 0.00019 21.1 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CCC66802.1 - 8.4e-09 34.8 1.5 0.001 19.1 0.0 4.9 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 CCC66802.1 - 1.5e-07 30.9 0.1 8.5e-07 28.5 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Auxin_repressed PF05564.7 CCC66802.1 - 1.1 9.8 7.9 13 6.4 0.1 3.2 2 1 0 2 2 2 0 Dormancy/auxin associated protein Uso1_p115_head PF04869.9 CCC66803.1 - 1.1e-103 346.3 8.6 1.1e-103 346.3 6.0 3.2 3 0 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Reo_sigmaC PF04582.7 CCC66803.1 - 3.1e-06 26.5 117.4 7.5e-05 22.0 6.0 10.2 1 1 9 11 11 11 6 Reovirus sigma C capsid protein ERM PF00769.14 CCC66803.1 - 3.3e-05 23.5 34.1 3.3e-05 23.5 23.7 9.6 1 1 8 9 9 9 3 Ezrin/radixin/moesin family ATG16 PF08614.6 CCC66803.1 - 0.0006 19.7 36.6 0.0006 19.7 25.4 12.6 1 1 11 12 12 12 3 Autophagy protein 16 (ATG16) Syntaxin PF00804.20 CCC66803.1 - 0.007 16.5 2.4 0.007 16.5 1.7 14.9 2 2 7 11 11 11 1 Syntaxin HrpB7 PF09486.5 CCC66803.1 - 0.0079 16.1 1.0 0.0079 16.1 0.7 10.7 3 2 7 12 12 12 2 Bacterial type III secretion protein (HrpB7) Filament PF00038.16 CCC66803.1 - 0.014 14.9 252.2 0.0045 16.5 39.4 8.4 1 1 6 7 7 7 0 Intermediate filament protein Rad52_Rad22 PF04098.10 CCC66804.1 - 2.6e-43 147.4 0.1 3.3e-43 147.0 0.1 1.1 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Ribosomal_S14 PF00253.16 CCC66805.1 - 6.4e-18 63.8 4.4 7e-18 63.7 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 CCC66805.1 - 0.044 13.8 2.0 0.95 9.5 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF4428 PF14471.1 CCC66805.1 - 0.045 13.4 0.5 0.053 13.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF2296 PF10058.4 CCC66805.1 - 0.16 11.7 1.8 2.1 8.1 0.0 2.1 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) RNA_POL_M_15KD PF02150.11 CCC66805.1 - 0.41 10.3 2.6 6.2 6.6 0.2 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit CTNNBL PF08216.6 CCC66806.1 - 0.0066 16.0 2.0 0.012 15.1 0.2 2.3 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear LON PF02190.11 CCC66806.1 - 0.077 12.6 3.7 0.057 13.0 0.5 2.3 2 0 0 2 2 2 0 ATP-dependent protease La (LON) domain UQ_con PF00179.21 CCC66807.1 - 2e-44 150.4 0.2 2.2e-44 150.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCC66807.1 - 1.5e-05 24.7 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCC66807.1 - 0.26 11.1 3.5 0.43 10.4 2.1 1.8 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 CCC66808.1 - 1.5e-43 149.1 17.2 2e-43 148.8 11.9 1.1 1 0 0 1 1 1 1 Pex19 protein family GerA PF03323.8 CCC66808.1 - 0.19 9.7 0.1 0.3 9.1 0.1 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein DUF3534 PF12053.3 CCC66808.1 - 1.2 8.9 4.5 0.51 10.1 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3534) DUF3347 PF11827.3 CCC66808.1 - 2 8.3 8.0 1.5 8.8 2.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3347) DUF4355 PF14265.1 CCC66808.1 - 7.8 6.4 15.4 0.28 11.1 1.6 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4355) Iso_dh PF00180.15 CCC66809.1 - 9.7e-67 225.3 0.0 1.1e-66 225.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4397 PF14344.1 CCC66809.1 - 0.088 13.1 0.0 0.26 11.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4397) Rxt3 PF08642.5 CCC66810.1 - 2.8e-28 98.4 0.2 1.3e-27 96.2 0.0 1.9 2 0 0 2 2 2 1 Histone deacetylation protein Rxt3 Ribosomal_L31e PF01198.14 CCC66811.1 - 1.6e-36 123.8 1.7 1.9e-36 123.6 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e MFS_1 PF07690.11 CCC66812.1 - 6.6e-29 100.7 61.8 2.2e-23 82.5 10.0 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCC66812.1 - 6.9e-06 24.9 39.2 3.1e-05 22.7 8.6 2.7 1 1 2 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 CCC66812.1 - 0.0016 16.9 3.6 0.0016 16.9 2.5 3.7 1 1 0 2 2 2 1 MFS/sugar transport protein BRE1 PF08647.6 CCC66813.1 - 5e-27 93.7 12.4 5e-27 93.7 8.6 6.2 3 1 2 5 5 3 1 BRE1 E3 ubiquitin ligase zf-C3HC4_3 PF13920.1 CCC66813.1 - 1e-06 28.3 11.5 2.1e-06 27.3 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC66813.1 - 1.6e-06 27.9 13.6 3.3e-06 27.0 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC66813.1 - 2.2e-05 24.0 13.3 4.4e-05 23.1 9.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCC66813.1 - 0.00015 21.3 14.2 0.00015 21.3 9.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCC66813.1 - 0.00086 19.0 11.1 0.0016 18.2 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain ATG16 PF08614.6 CCC66813.1 - 0.0047 16.7 22.3 0.0047 16.7 15.5 4.6 2 1 1 4 4 3 1 Autophagy protein 16 (ATG16) Prok-RING_4 PF14447.1 CCC66813.1 - 0.0062 16.0 5.5 0.015 14.8 3.8 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CCC66813.1 - 0.016 15.0 4.3 0.035 13.9 2.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CCC66813.1 - 0.019 14.6 7.9 0.085 12.5 5.5 2.2 1 0 0 1 1 1 0 RING-type zinc-finger DUF2379 PF09543.5 CCC66813.1 - 0.044 13.7 0.4 0.044 13.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) zf-RING_4 PF14570.1 CCC66813.1 - 1.5 8.4 11.7 3.8 7.1 8.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FYVE PF01363.16 CCC66813.1 - 7.4 6.5 13.4 1.4e+02 2.4 0.2 2.6 1 1 1 2 2 2 0 FYVE zinc finger zf-C3HC4_4 PF15227.1 CCC66813.1 - 8.3 6.3 10.7 23 4.9 7.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1765 PF08578.5 CCC66814.1 - 3.7e-20 72.2 9.4 3.7e-20 72.2 6.5 4.2 4 0 0 4 4 4 2 Protein of unknown function (DUF1765) DUF3927 PF13064.1 CCC66814.1 - 0.15 11.5 1.0 0.29 10.6 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3927) zf-C2H2_4 PF13894.1 CCC66815.1 - 7.6e-06 25.9 12.9 0.048 14.0 0.3 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCC66815.1 - 0.00024 21.1 1.4 0.13 12.4 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CCC66815.1 - 0.0014 18.8 18.2 0.088 13.1 1.2 4.0 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC66815.1 - 0.015 15.5 15.8 0.14 12.4 0.8 3.3 3 0 0 3 3 3 0 Zinc-finger double domain PTR2 PF00854.16 CCC66815.1 - 0.13 11.0 2.1 0.21 10.3 1.5 1.2 1 0 0 1 1 1 0 POT family Bap31 PF05529.7 CCC66816.1 - 2.5e-54 183.6 1.4 2.8e-54 183.5 1.0 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF4391 PF14335.1 CCC66816.1 - 6.5e-05 22.4 2.1 9.5e-05 21.8 1.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4391) OrfB_IS605 PF01385.14 CCC66816.1 - 0.019 14.3 2.8 0.028 13.8 2.0 1.2 1 0 0 1 1 1 0 Probable transposase Vps39_1 PF10366.4 CCC66819.1 - 7.2e-25 87.0 2.5 8.2e-25 86.9 0.3 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 CCC66819.1 - 4.6e-14 52.5 0.0 1.2e-13 51.1 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-C2H2_6 PF13912.1 CCC66819.1 - 0.27 11.1 3.1 0.25 11.2 0.7 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Pribosyl_synth PF14572.1 CCC66820.1 - 1.8e-39 135.3 0.7 4.2e-31 108.1 0.1 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CCC66820.1 - 2.1e-39 133.8 0.0 6.5e-39 132.2 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CCC66820.1 - 5.3e-07 29.4 0.3 1.1e-05 25.0 0.2 2.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Voldacs PF03517.8 CCC66821.1 - 6e-11 42.3 0.1 1e-10 41.5 0.1 1.4 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Orn_Arg_deC_N PF02784.11 CCC66822.1 - 1.1e-78 263.9 0.0 1.5e-78 263.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 CCC66822.1 - 3.9e-30 103.9 0.1 6.9e-30 103.1 0.1 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Rep_fac-A_3 PF08661.6 CCC66822.1 - 0.11 12.3 0.1 0.33 10.8 0.0 1.7 2 0 0 2 2 2 0 Replication factor A protein 3 GATA PF00320.22 CCC66823.1 - 2.7e-09 36.1 7.5 8.3e-09 34.6 5.2 1.9 1 0 0 1 1 1 1 GATA zinc finger Mtr2 PF10429.4 CCC66824.1 - 6.8e-71 237.3 0.1 7.9e-71 237.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 SUR7 PF06687.7 CCC66825.1 - 5.7e-21 75.0 9.5 4.5e-20 72.1 6.6 2.2 1 1 0 1 1 1 1 SUR7/PalI family nsp7 PF08716.5 CCC66825.1 - 0.0037 17.6 1.4 0.13 12.6 0.0 3.2 2 1 1 3 3 3 1 nsp7 replicase DUF3516 PF12029.3 CCC66825.1 - 0.026 13.3 0.4 0.05 12.4 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) DASH_Dad4 PF08650.5 CCC66825.1 - 0.1 12.5 2.9 0.95 9.4 0.3 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad4 Claudin_2 PF13903.1 CCC66825.1 - 0.26 10.9 11.5 0.037 13.7 4.8 2.0 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction FAD-SLDH PF12318.3 CCC66825.1 - 0.4 10.3 3.5 0.59 9.7 1.2 2.2 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase His_kinase PF06580.8 CCC66825.1 - 8.3 6.4 9.0 10 6.1 0.0 4.1 4 0 0 4 4 4 0 Histidine kinase ABC_membrane_2 PF06472.10 CCC66826.1 - 2.3e-75 253.3 7.2 3.1e-75 252.9 5.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CCC66826.1 - 1.9e-18 67.0 0.0 1.4e-16 61.0 0.0 2.9 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCC66826.1 - 1.3e-05 25.2 0.2 1.3e-05 25.2 0.2 2.8 2 2 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCC66826.1 - 0.013 14.7 0.0 0.03 13.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCC66826.1 - 0.015 15.3 0.0 0.042 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CCC66826.1 - 0.017 14.6 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.16 CCC66826.1 - 0.14 11.2 0.0 0.3 10.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Mo25 PF08569.6 CCC66827.1 - 1.3e-110 369.6 14.7 1.5e-110 369.3 10.2 1.1 1 0 0 1 1 1 1 Mo25-like Sigma54_activ_2 PF14532.1 CCC66828.1 - 0.034 14.2 0.0 0.086 12.8 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain EF-hand_1 PF00036.27 CCC66829.1 - 9.7e-24 80.8 13.1 2.6e-05 23.1 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 CCC66829.1 - 1.7e-18 64.7 5.5 0.00034 20.2 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 CCC66829.1 - 3.7e-18 65.4 5.5 1.2e-09 38.0 0.7 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 CCC66829.1 - 7.2e-15 53.5 18.1 0.0003 19.9 0.1 4.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 CCC66829.1 - 5.7e-12 45.0 15.0 0.0015 18.1 0.4 4.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 CCC66829.1 - 6.4e-07 29.0 9.6 0.0039 16.9 0.2 4.0 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 CCC66829.1 - 7.2e-06 26.0 0.0 0.031 14.3 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 CCC66829.1 - 0.001 18.9 0.0 1.1 9.2 0.0 2.8 2 1 1 3 3 3 2 EF-hand domain Diphthamide_syn PF01866.12 CCC66830.1 - 1.6e-44 152.4 0.0 1.2e-21 77.2 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein LRR_4 PF12799.2 CCC66831.1 - 4.9e-40 134.5 46.2 7.1e-10 38.2 3.0 7.3 4 2 4 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCC66831.1 - 5.4e-23 80.5 40.9 2.1e-10 40.1 0.9 6.1 4 1 3 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 CCC66831.1 - 9.2e-12 43.2 33.2 0.15 12.2 0.3 11.4 10 2 2 12 12 12 5 Leucine Rich Repeat LRR_9 PF14580.1 CCC66831.1 - 1.6e-09 37.6 16.6 1.5e-07 31.1 2.2 3.2 1 1 2 3 3 3 2 Leucine-rich repeat LRR_7 PF13504.1 CCC66831.1 - 2.2e-08 32.9 21.1 0.58 10.6 0.0 10.2 10 1 0 10 10 10 3 Leucine rich repeat LRR_6 PF13516.1 CCC66831.1 - 6.7e-07 28.7 30.4 0.55 10.4 0.1 10.8 9 3 2 11 11 11 2 Leucine Rich repeat DUF3744 PF12558.3 CCC66831.1 - 0.14 12.5 15.4 0.093 13.1 1.0 4.4 3 2 2 5 5 5 0 ATP-binding cassette cobalt transporter Glyco_hydro_4 PF02056.11 CCC66831.1 - 0.2 10.9 0.9 1.4 8.1 0.1 2.2 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase tRNA-synt_2b PF00587.20 CCC66832.1 - 3.1e-46 157.0 0.0 5.6e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCC66832.1 - 4.1e-14 52.2 0.1 6.6e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Anticodon binding domain CHCH PF06747.8 CCC66833.1 - 0.0018 18.1 5.1 0.0036 17.1 3.6 1.5 1 0 0 1 1 1 1 CHCH domain Longin PF13774.1 CCC66834.1 - 1.3e-15 56.7 0.0 2.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CCC66834.1 - 2.4e-15 55.8 1.2 4.1e-15 55.1 0.8 1.4 1 0 0 1 1 1 1 Synaptobrevin UPF0449 PF15136.1 CCC66834.1 - 0.047 13.9 0.7 0.075 13.2 0.5 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Tbf5 PF06331.7 CCC66834.1 - 0.095 12.4 0.4 0.17 11.6 0.3 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Cyclase_polyket PF04673.7 CCC66834.1 - 0.11 12.5 0.4 0.84 9.7 0.0 2.2 1 1 2 3 3 3 0 Polyketide synthesis cyclase FMN_dh PF01070.13 CCC66835.1 - 4.7e-118 394.0 0.0 5.9e-118 393.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCC66835.1 - 6.7e-23 80.2 0.0 1.9e-22 78.8 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CCC66835.1 - 7.1e-09 35.0 0.0 2.9e-08 33.0 0.0 1.9 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 CCC66835.1 - 0.0016 17.6 0.0 0.0032 16.6 0.0 1.5 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCC66835.1 - 0.0061 15.4 1.2 0.042 12.7 0.1 2.5 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 CCC66835.1 - 0.021 13.9 0.0 0.68 8.9 0.0 2.3 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 CCC66835.1 - 0.037 13.2 0.1 12 5.0 0.0 2.8 3 0 0 3 3 3 0 Histidine biosynthesis protein Tubulin_3 PF14881.1 CCC66835.1 - 0.078 12.4 0.1 0.35 10.3 0.0 2.0 1 1 1 2 2 2 0 Tubulin domain FMN_dh PF01070.13 CCC66836.1 - 1.3e-120 402.5 0.0 1.6e-120 402.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 CCC66836.1 - 9.2e-24 83.0 0.0 2.9e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 CCC66836.1 - 5.2e-09 35.4 0.1 3.3e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 CCC66836.1 - 4.6e-06 26.0 0.0 7.9e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCC66836.1 - 0.0026 16.7 1.3 0.028 13.3 0.1 2.6 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 CCC66836.1 - 0.015 14.3 0.1 0.61 9.1 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 CCC66836.1 - 0.015 14.5 0.1 4.9 6.3 0.0 2.7 3 0 0 3 3 3 0 Histidine biosynthesis protein SPC25 PF06703.6 CCC66837.1 - 2.4e-40 137.7 2.8 2.7e-40 137.5 2.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Lactate_perm PF02652.9 CCC66837.1 - 0.034 12.6 0.0 0.037 12.5 0.0 1.1 1 0 0 1 1 1 0 L-lactate permease DUF1900 PF08954.6 CCC66838.1 - 5.5e-32 110.1 0.0 1.3e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CCC66838.1 - 1.3e-21 75.9 0.1 2.4e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CCC66838.1 - 2.9e-21 74.5 5.2 2.7e-07 30.2 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat eIF2A PF08662.6 CCC66838.1 - 3.4e-05 23.6 0.1 0.0052 16.5 0.0 3.0 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 CCC66838.1 - 0.00056 19.1 0.0 0.0027 16.8 0.0 2.0 2 0 0 2 2 2 1 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 CCC66838.1 - 0.22 10.7 3.3 0.43 9.7 0.0 2.8 2 1 1 3 3 3 0 TUP1-like enhancer of split IMPDH PF00478.20 CCC66839.1 - 2.9e-140 467.1 1.0 3.4e-140 466.9 0.7 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 CCC66839.1 - 1.9e-17 62.7 0.0 1.2e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 CCC66839.1 - 4.1e-07 29.4 1.3 0.00048 19.3 0.5 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 CCC66839.1 - 3.5e-06 26.1 2.1 8.6e-06 24.8 0.9 1.8 2 1 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 CCC66839.1 - 0.00036 19.8 1.2 0.0025 17.1 0.9 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 CCC66839.1 - 0.0075 15.3 0.8 0.0075 15.3 0.5 1.6 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG Aldolase PF01081.14 CCC66839.1 - 0.009 15.1 0.1 0.031 13.4 0.1 1.9 1 0 0 1 1 1 1 KDPG and KHG aldolase EAL PF00563.15 CCC66839.1 - 0.051 13.0 0.1 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 EAL domain Metallophos PF00149.23 CCC66840.1 - 4.1e-42 143.8 0.8 8.1e-42 142.8 0.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RNR_inhib PF08591.5 CCC66841.1 - 0.00045 21.0 0.3 0.0011 19.8 0.2 1.5 1 1 0 1 1 1 1 Ribonucleotide reductase inhibitor cNMP_binding PF00027.24 CCC66843.1 - 3.8e-38 129.1 0.8 6.5e-17 61.1 0.0 4.9 5 0 0 5 5 5 3 Cyclic nucleotide-binding domain Patatin PF01734.17 CCC66843.1 - 1.4e-16 61.0 6.5 2.4e-15 56.9 2.7 3.2 2 1 0 2 2 2 1 Patatin-like phospholipase OGG_N PF07934.7 CCC66844.1 - 4.5e-21 74.9 0.6 8.2e-21 74.1 0.1 1.7 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 CCC66844.1 - 1.4e-19 70.3 0.0 2.5e-19 69.5 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PIF1 PF05970.9 CCC66845.1 - 1.6e-74 251.0 1.2 1e-71 241.8 0.8 2.2 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CCC66845.1 - 8.8e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCC66845.1 - 1.1e-06 28.8 0.0 3e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC66845.1 - 0.00059 19.8 0.1 0.002 18.1 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain Viral_helicase1 PF01443.13 CCC66845.1 - 0.0066 15.9 0.5 1.7 8.0 0.2 2.9 2 1 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA PF00004.24 CCC66845.1 - 0.0069 16.5 0.1 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UvrD_C_2 PF13538.1 CCC66845.1 - 0.0072 16.4 0.0 0.044 13.9 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain T2SE PF00437.15 CCC66845.1 - 0.0073 15.2 0.2 0.013 14.3 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 CCC66845.1 - 0.0084 15.8 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 CCC66845.1 - 0.039 13.4 0.0 0.081 12.3 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 CCC66845.1 - 0.053 13.1 0.0 0.29 10.7 0.0 2.2 2 1 1 3 3 3 0 NACHT domain RRM_1 PF00076.17 CCC66846.1 - 5.6e-29 99.5 2.4 5e-14 51.6 0.1 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC66846.1 - 1.6e-18 66.2 1.4 1.5e-09 37.5 0.0 3.2 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC66846.1 - 4.4e-18 65.0 0.5 2.5e-08 33.7 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCC66846.1 - 1.3e-07 31.2 0.0 0.0056 16.4 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 CCC66846.1 - 0.0005 19.7 0.3 0.6 9.8 0.1 2.8 2 1 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Trypan_PARP PF05887.6 CCC66846.1 - 0.01 15.6 11.3 0.022 14.5 7.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) SDA1 PF05285.7 CCC66846.1 - 0.057 12.6 12.2 0.12 11.6 8.4 1.5 1 0 0 1 1 1 0 SDA1 NESP55 PF06390.7 CCC66846.1 - 0.058 12.7 13.5 0.13 11.6 9.3 1.5 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Nop14 PF04147.7 CCC66846.1 - 0.93 7.3 18.0 1.4 6.7 12.5 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CCC66846.1 - 2.4 6.0 13.5 3.8 5.4 9.3 1.2 1 0 0 1 1 1 0 CDC45-like protein AAA_2 PF07724.9 CCC66847.1 - 2.2e-46 157.8 0.0 2.4e-45 154.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CCC66847.1 - 1.7e-23 83.2 0.1 7.1e-14 52.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CCC66847.1 - 2.1e-22 78.8 0.6 8.5e-22 76.8 0.4 2.2 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CCC66847.1 - 3.6e-16 59.1 0.0 1.4e-08 34.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.15 CCC66847.1 - 1.8e-12 46.9 10.3 9.2e-09 35.1 0.4 4.3 4 0 0 4 4 3 2 Clp amino terminal domain Sigma54_activat PF00158.21 CCC66847.1 - 2.9e-12 46.3 0.1 1.3e-08 34.5 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.1 CCC66847.1 - 7.5e-11 42.3 6.2 0.0003 20.8 0.0 5.0 4 2 2 6 6 5 2 AAA ATPase domain AAA_22 PF13401.1 CCC66847.1 - 7.6e-10 39.0 0.1 0.0016 18.5 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_17 PF13207.1 CCC66847.1 - 0.00011 23.0 5.3 0.24 12.1 0.0 4.3 4 1 0 4 4 3 2 AAA domain Mg_chelatase PF01078.16 CCC66847.1 - 0.00026 20.2 0.0 1.1 8.4 0.0 3.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI EzrA PF06160.7 CCC66847.1 - 0.00082 17.6 13.3 0.0015 16.7 9.2 1.4 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA Torsin PF06309.6 CCC66847.1 - 0.0011 18.8 0.0 0.0057 16.5 0.0 2.2 2 0 0 2 2 1 1 Torsin AAA_18 PF13238.1 CCC66847.1 - 0.0012 19.1 0.1 3.4 7.9 0.0 3.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCC66847.1 - 0.0019 17.3 0.3 0.094 11.8 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin AAA_33 PF13671.1 CCC66847.1 - 0.0036 17.1 0.0 0.28 11.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 CCC66847.1 - 0.0036 17.2 0.0 0.13 12.2 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 CCC66847.1 - 0.0036 17.0 0.0 2.5 7.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 CCC66847.1 - 0.0042 16.7 0.0 4 7.0 0.0 2.8 2 0 0 2 2 2 1 NACHT domain IstB_IS21 PF01695.12 CCC66847.1 - 0.0051 16.2 0.0 0.59 9.5 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein DUF815 PF05673.8 CCC66847.1 - 0.0053 15.7 0.2 0.2 10.5 0.0 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 CCC66847.1 - 0.008 16.4 2.7 1.4 9.1 0.0 3.6 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 CCC66847.1 - 0.018 14.5 0.0 2.7 7.5 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_3 PF07726.6 CCC66847.1 - 0.022 14.3 0.0 0.51 9.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 CCC66847.1 - 0.039 13.4 0.0 4.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 CCC66847.1 - 0.043 13.2 5.2 0.64 9.3 0.0 3.9 3 1 1 4 4 4 0 AAA-like domain RNA_helicase PF00910.17 CCC66847.1 - 0.046 13.9 0.1 7.1 6.8 0.0 2.9 3 0 0 3 3 2 0 RNA helicase Arch_ATPase PF01637.13 CCC66847.1 - 0.05 13.2 9.2 1.6 8.3 0.0 4.3 4 1 1 5 5 4 0 Archaeal ATPase DUF258 PF03193.11 CCC66847.1 - 0.052 12.7 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MobB PF03205.9 CCC66847.1 - 0.059 13.0 0.0 9 5.9 0.0 3.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PEPCK_ATP PF01293.15 CCC66847.1 - 0.083 11.4 0.0 0.14 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase TMF_DNA_bd PF12329.3 CCC66847.1 - 0.67 9.7 27.8 21 5.0 15.7 3.9 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 CCC66847.1 - 0.74 9.7 20.2 0.022 14.6 1.8 2.7 1 1 1 2 2 2 0 FlxA-like protein BLOC1_2 PF10046.4 CCC66847.1 - 6.2 7.0 12.0 3.7 7.7 3.3 3.2 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fe-S_biosyn PF01521.15 CCC66848.1 - 5e-18 65.0 0.0 1.7e-16 60.1 0.0 2.2 2 0 0 2 2 2 1 Iron-sulphur cluster biosynthesis XRCC4 PF06632.7 CCC66848.1 - 0.018 13.9 1.5 0.035 12.9 1.0 1.4 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Lipoprotein_10 PF03202.8 CCC66848.1 - 0.053 13.5 3.0 0.1 12.5 2.1 1.6 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region DUF4554 PF15091.1 CCC66848.1 - 3.3 6.3 7.3 4.2 5.9 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) Peptidase_M24 PF00557.19 CCC66849.1 - 2.5e-38 131.7 0.0 3.6e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CCC66849.1 - 7.8e-10 39.3 0.0 1.8e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain KH_3 PF13014.1 CCC66850.1 - 8.1e-09 34.9 0.1 0.0023 17.5 0.0 3.8 3 0 0 3 3 3 3 KH domain KH_1 PF00013.24 CCC66850.1 - 1.4e-08 34.2 0.1 0.0001 21.8 0.0 4.1 4 0 0 4 4 4 2 KH domain AAA PF00004.24 CCC66852.1 - 1.2e-93 310.1 0.0 2.9e-47 160.1 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCC66852.1 - 5.4e-15 55.0 0.0 1.1e-07 31.2 0.0 2.9 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCC66852.1 - 6e-12 45.9 0.3 0.0003 20.8 0.0 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 CCC66852.1 - 1.7e-11 45.0 0.0 1.8e-06 28.7 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCC66852.1 - 1.3e-10 41.5 0.1 0.0064 16.6 0.0 4.5 3 2 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 CCC66852.1 - 2.3e-10 39.9 0.0 0.00098 18.2 0.0 2.9 3 0 0 3 3 2 2 Zeta toxin AAA_14 PF13173.1 CCC66852.1 - 4.5e-10 39.5 0.0 0.002 17.9 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 CCC66852.1 - 7.3e-10 38.8 0.0 0.00037 20.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CCC66852.1 - 1.3e-09 37.9 0.2 0.0019 17.8 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCC66852.1 - 1.9e-09 37.6 0.0 0.00078 19.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 CCC66852.1 - 8.1e-09 34.6 0.0 0.00024 19.9 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_18 PF13238.1 CCC66852.1 - 1.2e-08 35.2 0.0 0.00014 22.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CCC66852.1 - 3.3e-07 30.4 0.0 0.026 14.7 0.0 2.8 2 0 0 2 2 2 2 RNA helicase ABC_tran PF00005.22 CCC66852.1 - 3.5e-07 30.6 0.1 0.02 15.1 0.0 3.1 3 0 0 3 3 2 2 ABC transporter IstB_IS21 PF01695.12 CCC66852.1 - 5.5e-07 29.1 0.2 0.016 14.5 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 CCC66852.1 - 6.4e-07 29.0 0.6 0.053 13.2 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain Vps4_C PF09336.5 CCC66852.1 - 9.6e-07 28.6 0.2 0.00056 19.7 0.1 3.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_28 PF13521.1 CCC66852.1 - 1.6e-06 28.1 0.0 0.035 14.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 CCC66852.1 - 2.4e-06 27.2 0.0 0.063 12.8 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CCC66852.1 - 4.7e-06 25.9 0.3 0.053 12.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 CCC66852.1 - 8.3e-06 25.3 2.6 0.78 9.1 0.0 4.3 2 2 2 5 5 5 2 AAA domain Cytidylate_kin2 PF13189.1 CCC66852.1 - 1e-05 25.5 0.1 0.0015 18.5 0.0 3.1 3 0 0 3 3 3 1 Cytidylate kinase-like family NACHT PF05729.7 CCC66852.1 - 1.3e-05 24.9 0.1 0.44 10.1 0.0 3.5 4 0 0 4 4 3 2 NACHT domain SKI PF01202.17 CCC66852.1 - 1.7e-05 24.7 0.0 0.088 12.6 0.0 3.0 3 0 0 3 3 2 2 Shikimate kinase Rad17 PF03215.10 CCC66852.1 - 0.00011 21.0 0.0 0.043 12.5 0.0 2.5 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Sigma54_activ_2 PF14532.1 CCC66852.1 - 0.00017 21.6 0.0 0.67 10.0 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 CCC66852.1 - 0.00019 21.2 0.0 1.8 8.1 0.0 3.4 2 1 1 3 3 3 2 Archaeal ATPase Sigma54_activat PF00158.21 CCC66852.1 - 0.0002 20.8 0.0 0.22 10.9 0.0 3.1 2 1 1 3 3 3 1 Sigma-54 interaction domain DUF815 PF05673.8 CCC66852.1 - 0.00021 20.3 0.0 0.095 11.6 0.0 2.9 3 0 0 3 3 2 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 CCC66852.1 - 0.0003 19.7 0.0 0.33 9.7 0.0 3.0 3 0 0 3 3 3 1 NB-ARC domain Viral_helicase1 PF01443.13 CCC66852.1 - 0.00039 20.0 0.0 0.92 8.9 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 CCC66852.1 - 0.0014 17.7 0.0 1.4 7.9 0.0 3.2 2 1 0 3 3 3 1 KaiC CPT PF07931.7 CCC66852.1 - 0.0014 18.2 0.0 0.031 13.8 0.0 2.3 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein AAA_11 PF13086.1 CCC66852.1 - 0.0017 17.9 2.0 0.39 10.2 0.0 3.3 4 0 0 4 4 3 1 AAA domain Parvo_NS1 PF01057.12 CCC66852.1 - 0.0021 17.0 0.0 1.6 7.5 0.0 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 CCC66852.1 - 0.0021 17.6 0.0 2.1 7.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.5 CCC66852.1 - 0.0037 16.4 0.0 1.2 8.2 0.0 3.0 3 0 0 3 3 2 1 Signal recognition particle receptor beta subunit ATP-synt_ab PF00006.20 CCC66852.1 - 0.0039 16.7 0.0 1.8 8.0 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PhoH PF02562.11 CCC66852.1 - 0.0061 15.8 0.1 1.5 8.0 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein UPF0079 PF02367.12 CCC66852.1 - 0.011 15.3 0.0 5.2 6.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 CCC66852.1 - 0.012 15.2 0.0 4.3 7.0 0.0 2.8 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 CCC66852.1 - 0.018 14.5 0.0 7.1 6.1 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AFG1_ATPase PF03969.11 CCC66852.1 - 0.02 13.6 0.3 4.9 5.8 0.1 3.0 2 1 0 2 2 2 0 AFG1-like ATPase ResIII PF04851.10 CCC66852.1 - 0.022 14.6 0.0 4.1 7.1 0.0 3.3 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit RRM_1 PF00076.17 CCC66852.1 - 0.036 13.7 0.1 0.76 9.4 0.0 2.8 3 0 0 3 3 3 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.18 CCC66852.1 - 0.051 13.5 0.0 3.1 7.7 0.0 2.9 2 1 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 CCC66852.1 - 0.058 12.5 0.0 0.81 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Guanylate_kin PF00625.16 CCC66852.1 - 0.062 12.7 0.8 8.9 5.7 0.0 3.9 4 1 1 5 5 4 0 Guanylate kinase AAA_29 PF13555.1 CCC66852.1 - 0.12 11.8 0.0 6.5 6.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 CCC66852.1 - 1.2 9.4 12.5 2.2 8.5 0.0 4.4 5 0 0 5 5 4 0 AAA domain Clp1 PF06807.9 CCC66853.1 - 2.6e-05 24.0 0.0 6.3e-05 22.8 0.0 1.7 2 0 0 2 2 2 1 Pre-mRNA cleavage complex II protein Clp1 Dynamin_N PF00350.18 CCC66853.1 - 0.0002 21.2 0.1 0.0038 17.0 0.1 2.5 2 1 0 2 2 2 1 Dynamin family MobB PF03205.9 CCC66853.1 - 0.00029 20.5 0.0 0.00058 19.5 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CCC66853.1 - 0.0019 18.0 0.4 0.017 14.9 0.2 2.3 1 1 1 2 2 2 1 AAA domain G-alpha PF00503.15 CCC66853.1 - 0.0037 15.9 2.0 0.0075 14.9 1.4 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Miro PF08477.8 CCC66853.1 - 0.023 15.1 0.0 0.056 13.9 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 CCC66853.1 - 0.024 14.5 0.3 0.096 12.6 0.2 2.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 CCC66853.1 - 0.031 14.5 0.1 0.31 11.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CCC66853.1 - 0.062 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ABC_tran PF00005.22 CCC66853.1 - 0.065 13.5 0.2 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 CCC66853.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_25 PF13481.1 CCC66853.1 - 0.2 11.0 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain WSC PF01822.14 CCC66854.1 - 2.3e-09 37.0 14.5 2.3e-09 37.0 10.1 2.8 2 1 0 2 2 2 1 WSC domain DUF912 PF06024.7 CCC66854.1 - 0.0028 17.6 0.1 0.0028 17.6 0.1 2.4 2 1 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) BPD_transp_2 PF02653.11 CCC66854.1 - 0.016 14.2 0.4 0.031 13.2 0.2 1.4 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Rifin_STEVOR PF02009.11 CCC66854.1 - 0.029 14.0 0.6 0.029 14.0 0.4 2.9 2 1 1 3 3 3 0 Rifin/stevor family Vpu PF00558.14 CCC66854.1 - 0.071 12.6 0.5 0.15 11.6 0.3 1.5 1 0 0 1 1 1 0 Vpu protein FixQ PF05545.6 CCC66854.1 - 4.4 7.0 7.2 0.13 11.9 0.2 2.0 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF1162 PF06650.7 CCC66855.1 - 1.2e-82 277.3 8.6 7e-80 268.1 0.7 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 CCC66855.1 - 1.8e-38 130.7 0.2 7.3e-38 128.7 0.1 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Fer2_3 PF13085.1 CCC66856.1 - 1.6e-31 108.3 0.0 3.1e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CCC66856.1 - 4.3e-10 39.7 6.8 4.3e-10 39.7 4.7 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CCC66856.1 - 3.9e-08 33.1 5.1 3.9e-08 33.1 3.5 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CCC66856.1 - 4.5e-06 26.9 1.3 4.5e-06 26.9 0.9 2.5 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.2 CCC66856.1 - 0.00014 22.1 3.8 0.00014 22.1 2.6 2.2 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 CCC66856.1 - 0.00018 21.2 5.2 0.00018 21.2 3.6 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 CCC66856.1 - 0.0016 18.6 7.8 0.036 14.3 0.5 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 CCC66856.1 - 0.0068 16.1 1.5 0.0068 16.1 1.0 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_20 PF14691.1 CCC66856.1 - 0.08 12.5 2.8 3.3 7.3 0.3 2.4 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_15 PF13459.1 CCC66856.1 - 4.7 7.8 8.7 0.36 11.4 0.2 2.5 3 0 0 3 3 3 0 4Fe-4S single cluster domain Autophagy_act_C PF03987.10 CCC66857.1 - 9.4e-07 28.9 3.3 1e-05 25.6 2.3 2.3 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain MIP PF00230.15 CCC66858.1 - 2.3e-72 243.1 5.2 3.5e-72 242.5 3.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein Ribosomal_L7Ae PF01248.21 CCC66859.1 - 2.9e-23 81.1 0.6 4.8e-23 80.5 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ferric_reduct PF01794.14 CCC66860.1 - 5e-22 78.3 19.9 8.6e-22 77.5 9.8 3.1 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CCC66860.1 - 1.3e-20 73.9 0.0 2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CCC66860.1 - 1.3e-20 73.1 0.0 2.6e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.19 CCC66860.1 - 0.072 13.2 0.0 0.2 11.7 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase FAD-binding domain Sugar_tr PF00083.19 CCC66861.1 - 1.7e-169 564.1 33.8 2e-169 563.9 23.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC66861.1 - 9.5e-29 100.1 28.0 9.8e-29 100.1 13.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Rhodanese PF00581.15 CCC66862.1 - 7.6e-10 39.1 0.0 9.5e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain SBF PF01758.11 CCC66863.1 - 2.8e-48 163.8 14.1 2.8e-48 163.8 9.8 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family TrbE PF11100.3 CCC66863.1 - 0.27 11.1 4.8 0.44 10.4 0.8 3.0 2 0 0 2 2 2 0 Conjugal transfer protein TrbE Flo11 PF10182.4 CCC66864.1 - 5.1e-41 139.7 0.5 5.1e-41 139.7 0.3 2.0 2 0 0 2 2 2 1 Flo11 domain Zn_clus PF00172.13 CCC66865.1 - 2.9e-08 33.4 11.7 2.9e-08 33.4 8.1 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 CCC66867.1 - 1.8e-15 57.0 0.0 2.3e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCC66867.1 - 5.8e-13 48.1 0.0 8e-13 47.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCC66867.1 - 2.9e-07 30.6 0.0 5.7e-07 29.7 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCC66867.1 - 4e-06 25.9 0.0 1.8e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 CCC66867.1 - 0.0095 16.2 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 CCC66867.1 - 0.02 13.8 0.1 0.036 12.9 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NmrA PF05368.8 CCC66867.1 - 0.021 14.0 0.0 0.039 13.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family DapB_N PF01113.15 CCC66867.1 - 0.029 14.2 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 CCC66867.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 CCC66867.1 - 0.08 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 CCC66867.1 - 0.1 12.5 0.0 0.35 10.7 0.0 1.9 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 CCC66867.1 - 0.13 11.0 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Methyltransf_11 PF08241.7 CCC66868.1 - 5.2e-16 58.9 0.0 1.4e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCC66868.1 - 2.4e-13 50.3 0.0 1.2e-11 44.9 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC66868.1 - 1.6e-11 44.2 0.0 5e-11 42.5 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC66868.1 - 3.5e-10 40.4 0.0 5.5e-09 36.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC66868.1 - 3.7e-10 40.0 0.0 1e-09 38.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC66868.1 - 3e-09 36.6 0.0 1e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCC66868.1 - 1.3e-05 24.4 0.0 1.9e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CCC66868.1 - 0.00033 20.6 0.0 0.00099 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCC66868.1 - 0.003 16.6 0.0 0.0047 16.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 CCC66868.1 - 0.0037 16.8 0.0 0.0056 16.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 CCC66868.1 - 0.0048 16.2 0.0 0.01 15.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_9 PF08003.6 CCC66868.1 - 0.025 13.2 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.5 CCC66868.1 - 0.053 13.0 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 CCC66868.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 CCC66868.1 - 0.11 11.6 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Aldo_ket_red PF00248.16 CCC66869.1 - 6.1e-64 215.5 0.0 6.9e-64 215.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 CCC66870.1 - 1.3e-37 129.3 33.5 1.3e-37 129.3 23.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCC66870.1 - 0.00049 18.4 4.2 0.0008 17.7 2.9 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CCC66870.1 - 0.0018 16.4 0.3 0.0032 15.6 0.2 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 CCC66870.1 - 1.1 7.2 18.9 0.033 12.2 1.5 3.3 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SKG6 PF08693.5 CCC66872.1 - 2.5e-07 29.8 1.1 5.3e-07 28.8 0.7 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 CCC66872.1 - 0.023 14.1 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Myb_DNA-bind_6 PF13921.1 CCC66873.1 - 4.8e-29 100.2 4.1 2e-10 40.6 0.0 3.9 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCC66873.1 - 6.6e-27 93.3 9.5 1.2e-11 44.5 0.1 4.0 3 1 0 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 CCC66873.1 - 0.11 12.4 5.2 1.3 8.9 0.8 3.3 1 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain PEPCK_ATP PF01293.15 CCC66874.1 - 5.9e-220 730.6 0.0 6.9e-220 730.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 CCC66874.1 - 0.011 15.6 0.0 0.078 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain SelA PF03841.8 CCC66874.1 - 0.035 12.8 0.0 0.062 12.0 0.0 1.3 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase AAA_29 PF13555.1 CCC66874.1 - 0.036 13.5 0.0 0.083 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 CCC66874.1 - 0.059 12.4 0.1 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 CCC66874.1 - 0.089 12.1 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PIN_4 PF13638.1 CCC66875.1 - 4.5e-10 39.7 0.1 4.5e-10 39.7 0.1 2.6 2 0 0 2 2 2 1 PIN domain Pcc1 PF09341.5 CCC66876.1 - 3.9e-21 74.8 0.0 4.4e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 DAGK_cat PF00781.19 CCC66877.1 - 2.5e-10 39.9 0.0 3.8e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ubiquitin PF00240.18 CCC66879.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CCC66879.1 - 3.2e-31 106.6 10.7 5.1e-31 106.0 7.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CCC66879.1 - 4.7e-20 71.0 0.7 6.5e-20 70.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCC66879.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCC66879.1 - 0.00011 21.9 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCC66879.1 - 0.0079 16.0 0.1 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCC66879.1 - 0.013 15.6 0.1 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 CCC66879.1 - 0.28 11.0 1.7 1.2 8.9 1.1 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain PTR2 PF00854.16 CCC66880.1 - 7.9e-58 196.0 14.2 1e-57 195.6 9.9 1.2 1 0 0 1 1 1 1 POT family SRP40_C PF05022.7 CCC66881.1 - 5.7e-30 103.6 4.8 2.4e-29 101.6 3.3 2.2 1 0 0 1 1 1 1 SRP40, C-terminal domain LIM PF00412.17 CCC66882.1 - 5.8e-15 55.1 26.5 1.7e-09 37.5 6.4 2.4 2 0 0 2 2 2 2 LIM domain DUF3336 PF11815.3 CCC66883.1 - 4.7e-39 133.2 4.7 4.7e-39 133.2 3.3 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CCC66883.1 - 3.7e-29 102.1 0.1 1e-28 100.7 0.0 1.8 2 0 0 2 2 2 1 Patatin-like phospholipase SNARE_assoc PF09335.6 CCC66884.1 - 2.1e-16 60.2 11.3 1.6e-15 57.4 4.0 2.9 2 1 1 3 3 3 1 SNARE associated Golgi protein LysM PF01476.15 CCC66884.1 - 0.084 12.7 0.3 0.92 9.4 0.0 2.8 4 0 0 4 4 4 0 LysM domain Cyt_c_ox_IV PF12270.3 CCC66884.1 - 0.15 11.8 0.1 0.15 11.8 0.0 2.3 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Ninjurin PF04923.7 CCC66884.1 - 0.38 10.4 3.9 4.2 7.1 1.0 2.4 2 0 0 2 2 2 0 Ninjurin DUF4231 PF14015.1 CCC66884.1 - 0.38 10.7 10.3 3.4 7.7 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF3754 PF12576.3 CCC66884.1 - 2.1 7.9 7.2 6.1 6.4 5.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3754) DUF4234 PF14018.1 CCC66884.1 - 3.3 7.4 11.9 10 5.9 0.5 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) DUF2207 PF09972.4 CCC66884.1 - 6.7 5.1 12.1 44 2.4 6.3 2.7 2 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Peptidase_M48 PF01435.13 CCC66885.1 - 2e-29 102.7 0.0 3e-29 102.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 HA2 PF04408.18 CCC66886.1 - 6e-24 84.0 0.0 2.2e-23 82.1 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCC66886.1 - 1e-21 76.8 0.0 3.4e-21 75.1 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCC66886.1 - 1.3e-13 50.6 0.4 2.9e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCC66886.1 - 4.9e-07 29.9 0.1 1.5e-06 28.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CCC66886.1 - 2.7e-06 26.9 1.1 7.7e-06 25.4 0.5 2.1 2 1 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 CCC66886.1 - 0.00087 18.2 0.0 0.0016 17.3 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 CCC66886.1 - 0.0012 17.9 0.0 0.0025 16.8 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 CCC66886.1 - 0.0013 18.6 3.3 0.28 11.0 0.0 3.2 1 1 2 3 3 3 2 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCC66886.1 - 0.0021 17.7 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CCC66886.1 - 0.0056 16.5 0.7 0.065 13.1 0.5 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCC66886.1 - 0.016 14.6 0.0 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 CCC66886.1 - 0.033 14.2 0.0 0.11 12.6 0.0 1.9 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 CCC66886.1 - 0.059 13.6 0.2 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.1 CCC66886.1 - 0.061 12.8 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 CCC66886.1 - 0.072 11.9 0.1 0.072 11.9 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 CCC66886.1 - 0.081 12.3 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 CCC66886.1 - 0.098 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain Vps5 PF09325.5 CCC66888.1 - 7.1e-30 104.0 11.9 1.1e-29 103.3 8.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CCC66888.1 - 2.1e-12 46.8 0.5 7.5e-12 45.0 0.4 2.0 1 0 0 1 1 1 1 PX domain Lactamase_B_2 PF12706.2 CCC66889.1 - 2e-38 131.9 0.2 3.9e-38 130.9 0.2 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 CCC66889.1 - 4e-24 83.8 0.0 9.3e-24 82.6 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 CCC66889.1 - 0.0079 15.8 0.0 0.017 14.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DASH_Dad2 PF08654.5 CCC66890.1 - 2e-28 98.3 4.9 5.5e-28 96.9 3.4 1.6 1 1 0 1 1 1 1 DASH complex subunit Dad2 FlaC_arch PF05377.6 CCC66890.1 - 0.002 17.9 0.8 0.0053 16.6 0.6 1.8 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) CesA PF11439.3 CCC66890.1 - 0.022 14.7 0.1 0.071 13.0 0.0 1.9 1 1 1 2 2 2 0 Type III secretion system filament chaperone CesA NuiA PF07924.6 CCC66890.1 - 0.024 14.5 0.3 4.4 7.2 0.0 2.1 2 0 0 2 2 2 0 Nuclease A inhibitor-like protein DASH_Duo1 PF08651.5 CCC66890.1 - 0.12 11.9 1.1 0.23 11.0 0.8 1.4 1 0 0 1 1 1 0 DASH complex subunit Duo1 Nucleoporin_C PF03177.9 CCC66891.1 - 1.3e-50 172.6 20.4 1.9e-50 172.0 14.1 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CCC66891.1 - 2.4e-50 171.5 9.2 3.6e-50 170.9 6.4 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Sir1 PF11603.3 CCC66892.1 - 0.00016 21.8 0.4 0.02 15.0 0.0 3.2 3 0 0 3 3 3 1 Regulatory protein Sir1 Helicase_C PF00271.26 CCC66892.1 - 0.0008 19.2 0.0 0.0032 17.2 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCC66892.1 - 0.018 14.5 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase THF_DHG_CYH PF00763.18 CCC66893.1 - 3.3e-20 72.2 0.0 1e-19 70.6 0.0 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 CCC66893.1 - 1.4e-17 63.1 0.0 3e-11 42.6 0.0 2.8 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MRP-L20 PF12824.2 CCC66894.1 - 7.1e-44 149.6 2.3 8.8e-44 149.3 1.6 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Syntaxin-18_N PF10496.4 CCC66895.1 - 4.2e-14 52.1 0.9 1.3e-13 50.6 0.6 1.9 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus SecG PF03840.9 CCC66895.1 - 0.0033 17.1 0.0 0.007 16.0 0.0 1.5 1 0 0 1 1 1 1 Preprotein translocase SecG subunit SNARE PF05739.14 CCC66895.1 - 0.014 15.0 7.5 0.014 15.0 5.2 2.0 2 0 0 2 2 2 0 SNARE domain GTP_EFTU PF00009.22 CCC66896.1 - 1.4e-44 151.8 0.1 1.8e-44 151.4 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 CCC66896.1 - 1.2e-11 44.5 5.8 1.2e-11 44.5 4.0 2.0 2 0 0 2 2 2 1 HBS1 N-terminus MMR_HSR1 PF01926.18 CCC66896.1 - 1.8e-06 27.8 0.1 8.6e-06 25.6 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D3 PF03143.12 CCC66896.1 - 0.0003 20.8 0.0 0.001 19.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Miro PF08477.8 CCC66896.1 - 0.00043 20.7 0.0 0.0036 17.7 0.0 2.5 1 1 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 CCC66896.1 - 0.014 15.2 0.1 5.5 6.7 0.0 2.8 1 1 1 2 2 2 0 Dynamin family GTP_EFTU_D2 PF03144.20 CCC66896.1 - 0.014 15.5 0.2 0.03 14.4 0.1 1.6 1 0 0 1 1 1 0 Elongation factor Tu domain 2 GST_C PF00043.20 CCC66897.1 - 4.5e-11 42.5 0.1 1.5e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCC66897.1 - 8.2e-07 29.1 0.0 3.2e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCC66897.1 - 2.1e-06 27.5 0.1 3.5e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCC66897.1 - 0.0064 16.9 0.1 0.011 16.1 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Epimerase PF01370.16 CCC66898.1 - 1.6e-18 66.9 0.1 2.1e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCC66898.1 - 6.9e-12 44.6 0.4 9.4e-12 44.2 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCC66898.1 - 2.3e-10 40.7 0.1 4.2e-10 39.9 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCC66898.1 - 2.3e-09 36.5 0.2 1.8e-08 33.6 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CCC66898.1 - 2.7e-05 24.1 0.2 6.3e-05 22.9 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 CCC66898.1 - 6.4e-05 22.3 0.1 0.00049 19.4 0.0 2.2 2 1 0 2 2 2 1 NmrA-like family KR PF08659.5 CCC66898.1 - 0.0048 16.5 0.0 0.0099 15.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CCC66898.1 - 0.036 12.9 0.4 0.15 10.9 0.0 2.1 2 1 0 3 3 3 0 Polysaccharide biosynthesis protein Response_reg PF00072.19 CCC66898.1 - 0.046 13.7 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 2 0 Response regulator receiver domain adh_short_C2 PF13561.1 CCC66898.1 - 0.052 13.3 0.6 0.3 10.7 0.1 2.4 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_2 PF03446.10 CCC66898.1 - 0.11 12.3 0.0 3.9 7.2 0.0 2.4 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Ribonuc_2-5A PF06479.7 CCC66900.1 - 0.069 12.9 0.2 0.13 12.0 0.2 1.3 1 0 0 1 1 1 0 Ribonuclease 2-5A GST_N_2 PF13409.1 CCC66901.1 - 5.5e-22 77.5 0.0 1.6e-21 76.0 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCC66901.1 - 1.5e-08 34.4 0.0 3.5e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCC66901.1 - 0.00012 22.2 0.0 0.32 11.2 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Calici_coat_C PF08435.6 CCC66903.1 - 0.0017 17.7 0.6 0.0029 16.9 0.4 1.4 1 0 0 1 1 1 1 Calicivirus coat protein C-terminal Put_Phosphatase PF06888.7 CCC66903.1 - 0.012 14.8 0.9 0.04 13.0 0.1 2.1 1 1 1 2 2 2 0 Putative Phosphatase XPG_I_2 PF12813.2 CCC66903.1 - 0.22 10.9 4.1 0.11 11.9 0.2 2.0 2 0 0 2 2 2 0 XPG domain containing TORC_N PF12884.2 CCC66903.1 - 4.6 7.8 9.0 1.5 9.4 0.4 3.3 3 2 0 3 3 3 0 Transducer of regulated CREB activity, N terminus DUF3635 PF12330.3 CCC66904.1 - 2.8e-19 68.9 0.0 1.9e-18 66.3 0.0 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) WD40 PF00400.27 CCC66905.1 - 2e-43 144.7 14.4 5.7e-11 41.8 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat Hira PF07569.6 CCC66905.1 - 4.7e-07 29.2 0.0 1.6e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 TUP1-like enhancer of split eIF2A PF08662.6 CCC66905.1 - 0.00018 21.2 0.1 1.5 8.5 0.0 4.4 5 0 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 CCC66905.1 - 0.00067 19.1 0.7 0.0025 17.3 0.5 2.0 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 CCC66905.1 - 0.0031 17.1 0.1 29 4.4 0.0 4.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 CCC66905.1 - 0.007 15.4 0.0 0.061 12.4 0.0 2.6 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Aconitase PF00330.15 CCC66906.1 - 2.1e-188 626.5 0.0 2.5e-188 626.3 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCC66906.1 - 2.2e-45 153.9 0.0 5.8e-45 152.6 0.0 1.8 1 0 0 1 1 1 1 Aconitase C-terminal domain SH3_1 PF00018.23 CCC66907.1 - 7.8e-38 127.6 4.6 3.7e-12 45.4 0.1 4.4 4 0 0 4 4 4 3 SH3 domain SHD1 PF03983.7 CCC66907.1 - 1.3e-34 117.7 0.1 3.1e-34 116.4 0.0 1.7 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_9 PF14604.1 CCC66907.1 - 7.9e-33 111.8 7.2 1.1e-10 40.8 0.0 4.1 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 CCC66907.1 - 8.9e-32 108.3 0.0 1.9e-08 33.6 0.0 4.5 4 0 0 4 4 4 4 Variant SH3 domain Molydop_binding PF01568.16 CCC66907.1 - 0.01 15.6 0.0 0.29 10.9 0.0 2.7 2 0 0 2 2 2 0 Molydopterin dinucleotide binding domain DUF3104 PF11302.3 CCC66907.1 - 0.11 11.8 0.1 0.33 10.3 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) SpoVA PF03862.8 CCC66907.1 - 1.7 8.7 8.2 16 5.6 0.1 4.0 3 2 1 4 4 4 0 SpoVA protein Rsc14 PF08586.5 CCC66908.1 - 1.8e-25 89.3 0.4 4.4e-24 84.8 0.3 2.4 1 1 0 1 1 1 1 RSC complex, Rsc14/Ldb7 subunit LDB19 PF13002.2 CCC66908.1 - 0.038 13.5 0.1 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 Arrestin_N terminal like ERG4_ERG24 PF01222.12 CCC66910.1 - 2.8e-185 615.9 31.0 3.2e-185 615.7 21.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family HEAT PF02985.17 CCC66911.1 - 1.2e-14 52.9 15.9 0.00096 19.0 0.0 10.0 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 CCC66911.1 - 1.6e-14 53.9 14.8 2.3e-06 27.8 0.0 9.9 9 2 3 12 12 12 4 HEAT-like repeat IBN_N PF03810.14 CCC66911.1 - 1.7e-12 47.0 3.8 1.7e-12 47.0 2.6 3.4 4 0 0 4 4 4 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 CCC66911.1 - 1.1e-10 41.5 11.9 4e-05 23.8 0.0 7.0 4 1 4 8 8 8 4 HEAT repeats Arm PF00514.18 CCC66911.1 - 2e-05 24.2 8.0 1 9.2 0.0 7.3 8 0 0 8 8 8 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 CCC66911.1 - 4.5e-05 22.9 1.1 0.11 11.8 0.0 4.3 2 1 0 4 4 4 1 CLASP N terminal Mito_carr PF00153.22 CCC66912.1 - 4.3e-55 183.4 0.4 1.6e-17 62.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein LRR_4 PF12799.2 CCC66913.1 - 0.00056 19.4 22.8 0.0025 17.4 0.4 5.8 6 1 1 7 7 7 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCC66913.1 - 0.036 13.8 0.6 0.036 13.8 0.4 5.1 8 0 0 8 8 8 0 Leucine rich repeat LRR_1 PF00560.28 CCC66913.1 - 0.053 13.5 16.3 5 7.5 0.2 7.0 6 1 1 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.1 CCC66913.1 - 1.1 9.5 24.0 4.5 7.6 0.0 7.9 9 0 0 9 9 9 0 Leucine Rich repeat NOA36 PF06524.7 CCC66914.1 - 0.2 10.8 12.2 0.58 9.3 8.5 1.8 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 CCC66914.1 - 0.44 10.1 9.6 0.048 13.2 3.0 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Fungal_trans PF04082.13 CCC66915.1 - 8.9e-22 77.1 9.8 7.6e-21 74.1 6.8 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC66915.1 - 9.4e-07 28.6 10.6 9.4e-07 28.6 7.4 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain hGDE_central PF14702.1 CCC66915.1 - 0.0083 15.3 0.0 0.021 14.0 0.0 1.6 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme FlxA PF14282.1 CCC66915.1 - 2 8.4 7.0 5.9 6.9 4.9 1.8 1 0 0 1 1 1 0 FlxA-like protein Fungal_trans PF04082.13 CCC66916.1 - 1.1e-26 93.3 5.5 1.1e-26 93.3 3.8 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC66916.1 - 2.3e-08 33.8 12.2 4.2e-08 32.9 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain XRCC1_N PF01834.11 CCC66916.1 - 0.083 12.3 1.6 0.1 12.0 0.3 1.7 2 0 0 2 2 2 0 XRCC1 N terminal domain 6PF2K PF01591.13 CCC66917.1 - 3.4e-60 202.8 2.8 4.8e-60 202.3 1.9 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCC66917.1 - 6.2e-24 84.8 0.0 1.2e-23 83.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CCC66917.1 - 2.6e-05 24.1 0.0 6.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCC66917.1 - 0.0084 15.3 0.4 0.013 14.7 0.3 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 DUF1198 PF06711.6 CCC66917.1 - 0.11 12.3 0.4 9.9 5.9 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1198) NUC173 PF08161.7 CCC66918.1 - 2.8e-75 252.0 0.4 2.2e-73 245.8 0.2 3.4 3 0 0 3 3 3 1 NUC173 domain HEAT PF02985.17 CCC66918.1 - 5.9e-07 29.0 0.2 1.8 8.8 0.0 5.5 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 CCC66918.1 - 0.00021 21.4 0.8 16 5.8 0.0 4.6 4 1 1 5 5 5 1 HEAT repeats Inh PF02974.9 CCC66918.1 - 0.0066 15.9 0.0 0.033 13.7 0.0 2.2 2 0 0 2 2 2 1 Protease inhibitor Inh BacA PF02673.13 CCC66918.1 - 0.034 13.3 0.1 0.067 12.3 0.1 1.5 1 0 0 1 1 1 0 Bacitracin resistance protein BacA HEAT_EZ PF13513.1 CCC66918.1 - 0.042 14.3 1.2 77 3.9 0.0 5.2 6 0 0 6 6 6 0 HEAT-like repeat DUF2435 PF10363.4 CCC66918.1 - 0.047 13.5 3.2 6.1 6.8 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2435) UME PF08064.8 CCC66918.1 - 1.4 8.9 10.1 1.2 9.1 0.1 4.8 5 0 0 5 5 5 0 UME (NUC010) domain Bromo_TP PF07524.8 CCC66919.1 - 1.1e-09 37.8 0.1 2.1e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated NusB PF01029.13 CCC66919.1 - 0.039 13.9 1.3 8.7 6.3 0.4 2.5 2 0 0 2 2 2 0 NusB family TFIID-18kDa PF02269.11 CCC66919.1 - 0.039 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit Clat_adaptor_s PF01217.15 CCC66920.1 - 1.1e-09 38.1 0.3 1.9e-09 37.3 0.1 1.4 2 0 0 2 2 2 1 Clathrin adaptor complex small chain Maf PF02545.9 CCC66920.1 - 0.11 11.6 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 Maf-like protein Rad21_Rec8_N PF04825.8 CCC66921.1 - 3.3e-18 65.6 0.1 8.5e-18 64.3 0.1 1.6 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein T2SF PF00482.18 CCC66921.1 - 0.043 13.7 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Rad21_Rec8 PF04824.11 CCC66921.1 - 0.073 12.2 0.1 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 Conserved region of Rad21 / Rec8 like protein AKAP7_RIRII_bdg PF10470.4 CCC66921.1 - 0.44 10.4 4.6 21 5.0 0.6 3.3 3 0 0 3 3 3 0 PKA-RI-RII subunit binding domain of A-kinase anchor protein ICL PF00463.16 CCC66922.1 - 4.9e-167 556.3 0.0 5.6e-167 556.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CCC66922.1 - 1.7e-08 33.9 0.0 2.6e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Mannosyl_trans3 PF11051.3 CCC66923.1 - 1.7e-84 283.3 1.8 1.7e-84 283.3 0.0 1.9 3 0 0 3 3 3 1 Mannosyltransferase putative E1-E2_ATPase PF00122.15 CCC66925.1 - 4.3e-15 55.3 1.0 7.9e-15 54.5 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CCC66925.1 - 1.2e-13 50.8 0.0 3.4e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCC66925.1 - 2.2e-13 50.8 0.1 5.2e-13 49.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC66925.1 - 2.2e-09 38.0 0.3 2.3e-07 31.4 0.2 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCC66925.1 - 0.0014 18.2 0.3 0.0043 16.6 0.2 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF281 PF03436.8 CCC66925.1 - 0.1 12.6 0.0 0.31 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF281) RRM_1 PF00076.17 CCC66926.1 - 7.8e-86 281.7 8.6 5e-22 77.3 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC66926.1 - 4.7e-61 202.6 0.4 6.1e-16 58.1 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC66926.1 - 6.2e-47 157.2 0.2 1.2e-10 41.0 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 CCC66926.1 - 3.3e-22 77.9 1.4 2.1e-21 75.3 0.1 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 CCC66926.1 - 7.7e-06 25.7 9.5 0.37 10.6 0.0 5.1 4 1 1 5 5 5 2 RNA binding motif Nup35_RRM PF05172.8 CCC66926.1 - 1.5e-05 24.6 0.1 0.03 14.0 0.0 3.7 3 1 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CCC66926.1 - 0.0015 18.2 0.7 11 5.8 0.0 3.8 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif CbiG_mid PF11761.3 CCC66926.1 - 0.0022 18.1 0.0 0.42 10.8 0.0 2.7 2 0 0 2 2 2 1 Cobalamin biosynthesis central region LON PF02190.11 CCC66926.1 - 0.0035 17.0 0.0 0.018 14.7 0.0 2.0 1 1 1 2 2 2 1 ATP-dependent protease La (LON) domain TC1 PF15063.1 CCC66926.1 - 0.011 15.3 0.0 0.1 12.1 0.0 2.5 2 0 0 2 2 2 0 Thyroid cancer protein 1 OB_RNB PF08206.6 CCC66926.1 - 0.032 13.7 5.1 10 5.7 0.1 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain SNF2_N PF00176.18 CCC66927.1 - 6.7e-77 258.2 0.8 1.9e-76 256.6 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF4208 PF13907.1 CCC66927.1 - 1.3e-27 95.9 0.4 1.3e-27 95.9 0.3 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Chromo PF00385.19 CCC66927.1 - 5.6e-25 86.7 3.4 1.9e-15 56.2 0.1 3.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 CCC66927.1 - 2.8e-15 55.9 0.0 1.2e-14 53.8 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Myb_DNA-bind_6 PF13921.1 CCC66927.1 - 0.0039 17.2 0.4 0.031 14.3 0.0 2.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCC66927.1 - 0.014 15.4 0.0 0.063 13.3 0.0 2.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Copper-fist PF00649.13 CCC66928.1 - 2.3e-20 71.5 3.5 2.3e-20 71.5 2.4 2.5 2 0 0 2 2 2 1 Copper fist DNA binding domain DUF1116 PF06545.6 CCC66928.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1116) ChaC PF04752.7 CCC66929.1 - 1.3e-55 188.0 0.0 1.8e-55 187.6 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein ThaI PF15514.1 CCC66929.1 - 0.13 11.5 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease ThaI Rad4 PF03835.10 CCC66930.1 - 1.3e-33 115.4 3.3 1.3e-33 115.4 2.3 2.3 3 0 0 3 3 3 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 CCC66930.1 - 7.8e-25 86.3 0.1 1.5e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 CCC66930.1 - 6.4e-17 60.8 0.2 1.5e-16 59.6 0.1 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 CCC66930.1 - 2e-10 40.7 2.0 4.3e-10 39.7 0.1 2.7 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 CCC66930.1 - 0.0012 19.0 0.1 0.0038 17.4 0.0 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily SPT2 PF08243.6 CCC66931.1 - 8.5e-28 96.9 27.8 8.5e-28 96.9 19.2 2.6 2 1 1 3 3 3 1 SPT2 chromatin protein CBFD_NFYB_HMF PF00808.18 CCC66932.1 - 2.2e-12 46.8 0.1 2.9e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCC66932.1 - 0.00031 20.7 0.0 0.00045 20.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CLIP PF12032.3 CCC66932.1 - 0.0049 16.9 0.0 0.009 16.0 0.0 1.5 1 0 0 1 1 1 1 Regulatory CLIP domain of proteinases DUF1732 PF08340.6 CCC66932.1 - 0.022 14.5 0.0 0.052 13.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) Cadherin_2 PF08266.7 CCC66932.1 - 0.095 12.2 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Cadherin-like Sec34 PF04136.10 CCC66935.1 - 3.1e-24 85.4 5.4 3.1e-24 85.4 3.8 2.9 3 0 0 3 3 3 1 Sec34-like family UPF0160 PF03690.8 CCC66936.1 - 3.3e-121 404.5 0.0 3.8e-121 404.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Dimer_Tnp_hAT PF05699.9 CCC66937.1 - 8.7e-09 34.8 0.2 3.2e-08 33.0 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 CCC66937.1 - 0.023 14.4 0.6 0.052 13.3 0.4 1.7 1 0 0 1 1 1 0 BED zinc finger RhoGAP PF00620.22 CCC66938.1 - 1e-38 132.3 0.4 4.1e-38 130.3 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain RasGEF PF00617.14 CCC66938.1 - 8.7e-20 71.2 3.9 2.8e-17 63.0 0.1 3.9 3 0 0 3 3 3 2 RasGEF domain RasGEF_N PF00618.15 CCC66938.1 - 2.7e-19 69.2 0.9 3.3e-18 65.7 0.6 3.0 1 0 0 1 1 1 1 RasGEF N-terminal motif 60KD_IMP PF02096.15 CCC66939.1 - 5.7e-40 137.0 1.3 5.7e-40 137.0 0.9 1.8 2 0 0 2 2 2 1 60Kd inner membrane protein DUF2636 PF11120.3 CCC66939.1 - 0.1 12.1 0.0 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2636) PET122 PF05476.6 CCC66940.1 - 1.4e-90 303.1 2.4 1.8e-90 302.8 1.6 1.0 1 0 0 1 1 1 1 PET122 Aminotran_1_2 PF00155.16 CCC66941.1 - 5.5e-19 68.3 0.0 6.9e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 CCC66941.1 - 0.00012 20.7 0.0 0.00015 20.4 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase UCH PF00443.24 CCC66942.1 - 7.6e-54 182.6 1.3 1.9e-53 181.3 0.9 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Metallophos PF00149.23 CCC66943.1 - 6.6e-41 139.9 0.1 8.1e-41 139.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCC66943.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DMPK_coil PF08826.5 CCC66944.1 - 1.6 8.7 21.3 0.071 13.0 2.2 3.2 3 0 0 3 3 3 0 DMPK coiled coil domain like DUF4061 PF13270.1 CCC66944.1 - 6.5 6.9 13.5 0.041 13.9 2.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4061) TBP PF00352.16 CCC66945.1 - 8.3e-70 230.1 0.1 4.5e-35 118.8 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 CCC66945.1 - 0.00065 19.7 2.6 0.67 10.0 0.0 2.9 3 1 1 4 4 4 2 Domain of unknown function (DUF3378) Cohesin_load PF10345.4 CCC66946.1 - 1.2e-91 307.8 35.2 1.5e-91 307.4 24.4 1.1 1 0 0 1 1 1 1 Cohesin loading factor LSM PF01423.17 CCC66947.1 - 1.2e-14 53.5 0.1 1.5e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain FTR1 PF03239.9 CCC66948.1 - 1.1e-94 316.9 6.6 1.3e-94 316.6 4.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family CoA_binding_3 PF13727.1 CCC66948.1 - 0.55 10.0 0.0 0.55 10.0 0.0 2.3 3 0 0 3 3 3 0 CoA-binding domain UCH PF00443.24 CCC66949.1 - 1.3e-63 214.6 1.1 1.3e-63 214.6 0.7 1.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC66949.1 - 2.4e-32 112.5 1.0 6e-32 111.2 0.4 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 CCC66949.1 - 4.1e-05 23.8 0.1 0.00022 21.5 0.1 2.1 1 1 0 1 1 1 1 Rhodanese-like domain WWbp PF10349.4 CCC66949.1 - 0.057 14.3 1.7 0.12 13.3 1.2 1.5 1 0 0 1 1 1 0 WW-domain ligand protein Asp_protease PF09668.5 CCC66950.1 - 9.5e-50 167.3 0.0 2.2e-49 166.1 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease Asp_protease_2 PF13650.1 CCC66950.1 - 2.8e-10 40.5 0.1 5.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease UBA PF00627.26 CCC66950.1 - 2.8e-06 27.0 0.0 7.1e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 UBA/TS-N domain gag-asp_proteas PF13975.1 CCC66950.1 - 8.3e-06 25.5 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 CCC66950.1 - 2.8e-05 24.0 0.0 6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 CCC66950.1 - 4.8e-05 23.2 0.0 0.00011 22.0 0.0 1.6 1 0 0 1 1 1 1 Retroviral aspartyl protease Pyr_redox_2 PF07992.9 CCC66951.1 - 2.9e-28 99.1 0.0 3.9e-18 66.0 0.0 3.9 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCC66951.1 - 1.2e-12 48.0 0.0 4.2e-11 43.0 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCC66951.1 - 5.2e-06 26.6 0.2 0.002 18.2 0.0 3.2 1 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HTH_psq PF05225.11 CCC66952.1 - 3e-06 26.6 0.3 3e-06 26.6 0.2 2.7 3 1 0 3 3 3 1 helix-turn-helix, Psq domain Jnk-SapK_ap_N PF09744.4 CCC66954.1 - 0.013 15.5 9.5 0.023 14.6 6.6 1.4 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 DUF1759 PF03564.10 CCC66954.1 - 0.089 12.6 5.2 0.17 11.7 0.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1759) DUF743 PF05332.6 CCC66954.1 - 0.17 11.8 1.6 0.34 10.8 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF743) Ribosomal_S9 PF00380.14 CCC66955.1 - 6.7e-39 132.8 0.2 7.6e-39 132.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Glyco_trans_1_3 PF13528.1 CCC66955.1 - 0.032 13.4 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 Ribosomal_L13e PF01294.13 CCC66956.1 - 2.6e-70 235.5 4.8 3.4e-70 235.1 3.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e 4HBT_3 PF13622.1 CCC66956.1 - 0.046 13.4 0.2 0.056 13.1 0.2 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Ribosomal_60s PF00428.14 CCC66957.1 - 7.4e-21 74.3 8.7 8.9e-21 74.0 6.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein TPP_enzyme_N PF02776.13 CCC66958.1 - 2.8e-30 105.0 0.0 6.2e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCC66958.1 - 9.1e-25 87.0 0.0 1.7e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCC66958.1 - 2.2e-13 50.0 0.0 3.9e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Pkinase PF00069.20 CCC66959.1 - 1.1e-60 204.9 0.0 1.3e-60 204.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC66959.1 - 1.8e-26 92.7 0.0 2.4e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CCC66959.1 - 0.0037 16.8 0.7 0.0055 16.3 0.5 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CCC66959.1 - 0.0052 16.5 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ldh_1_N PF00056.18 CCC66960.1 - 1.5e-41 141.5 0.1 2.5e-41 140.8 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CCC66960.1 - 4.1e-38 130.8 0.1 6e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 CCC66960.1 - 0.00042 19.0 0.0 0.00065 18.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CCC66960.1 - 0.0042 17.3 0.0 0.011 15.9 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain SRP1_TIP1 PF00660.12 CCC66962.1 - 5.6e-07 29.3 2.7 1.5e-06 27.9 0.3 2.5 2 0 0 2 2 2 1 Seripauperin and TIP1 family Sec3_C PF09763.4 CCC66962.1 - 0.025 12.7 1.7 0.024 12.7 1.2 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec3 Apt1 PF10351.4 CCC66962.1 - 3.1 6.5 14.4 4.6 6.0 10.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain MDFI PF15316.1 CCC66962.1 - 4.6 7.1 8.9 7.7 6.4 6.2 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Pol_alpha_B_N PF08418.5 CCC66962.1 - 7.3 6.0 21.0 13 5.1 14.5 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RIC1 PF07064.8 CCC66963.1 - 2.4e-10 40.2 3.4 2.4e-10 40.2 2.3 2.4 2 1 0 2 2 2 1 RIC1 COX6B PF02297.12 CCC66964.1 - 1.5e-20 72.9 5.1 1.8e-20 72.7 3.6 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Somatostatin PF03002.10 CCC66964.1 - 0.014 15.0 0.3 0.029 13.9 0.2 1.5 1 0 0 1 1 1 0 Somatostatin/Cortistatin family APOBEC_C PF05240.9 CCC66964.1 - 0.07 12.5 1.1 0.11 11.9 0.7 1.3 1 0 0 1 1 1 0 APOBEC-like C-terminal domain ketoacyl-synt PF00109.21 CCC66964.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain UCR_hinge PF02320.11 CCC66964.1 - 0.25 11.3 1.5 0.37 10.7 0.7 1.6 1 1 1 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.7 CCC66964.1 - 0.4 10.5 5.7 1.3 8.8 1.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) HATPase_c_3 PF13589.1 CCC66965.1 - 3.6e-11 42.8 0.3 3.6e-11 42.8 0.2 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 CCC66965.1 - 7.9e-10 38.2 0.2 2.3e-09 36.7 0.1 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 CCC66965.1 - 7.8e-09 35.2 0.1 1.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dimer_Tnp_hAT PF05699.9 CCC66966.1 - 8.7e-09 34.8 0.2 3.2e-08 33.0 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 CCC66966.1 - 0.023 14.4 0.6 0.052 13.3 0.4 1.7 1 0 0 1 1 1 0 BED zinc finger Nramp PF01566.13 CCC66967.1 - 5.6e-95 318.1 14.1 7.7e-95 317.7 9.8 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF4131 PF13567.1 CCC66967.1 - 6.6 6.1 14.8 0.27 10.6 2.5 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Bromodomain PF00439.20 CCC66968.1 - 1.5e-05 24.8 2.6 1.7e-05 24.6 0.2 2.4 2 1 0 2 2 2 1 Bromodomain HA2 PF04408.18 CCC66969.1 - 1.3e-27 95.8 0.2 6.4e-27 93.5 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCC66969.1 - 4.2e-14 52.1 0.0 1.7e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 CCC66969.1 - 4.4e-14 52.2 0.0 1.5e-13 50.5 0.0 1.9 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 CCC66969.1 - 1e-07 31.5 0.0 2.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCC66969.1 - 2.8e-06 27.4 0.1 1.9e-05 24.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CCC66969.1 - 0.0077 15.3 2.9 0.011 14.8 0.1 2.6 2 1 1 3 3 3 1 KaiC T2SE PF00437.15 CCC66969.1 - 0.0081 15.0 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 CCC66969.1 - 0.025 13.8 0.0 0.065 12.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein HTH_37 PF13744.1 CCC66969.1 - 0.031 14.0 0.3 0.12 12.1 0.2 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain SNF2_N PF00176.18 CCC66970.1 - 1.3e-66 224.4 0.2 2.2e-66 223.6 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 CCC66970.1 - 4.3e-13 49.1 0.0 8.8e-13 48.1 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 CCC66970.1 - 1.7e-10 40.5 0.0 4.3e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 CCC66970.1 - 3.5e-08 33.1 5.9 6.2e-08 32.3 4.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCC66970.1 - 3e-07 30.3 7.4 5.8e-07 29.4 5.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 CCC66970.1 - 4.3e-07 29.5 0.0 9.7e-07 28.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_3 PF13920.1 CCC66970.1 - 6.2e-07 28.9 3.8 1e-06 28.2 2.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC66970.1 - 7.9e-07 28.7 6.9 1.4e-06 27.8 4.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 CCC66970.1 - 2.2e-06 27.2 7.8 4.1e-06 26.3 5.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCC66970.1 - 0.0028 17.5 8.5 0.0053 16.5 5.9 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCC66970.1 - 0.0028 17.3 2.1 0.0093 15.6 1.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 CCC66970.1 - 0.016 15.3 1.2 0.033 14.3 0.8 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 CCC66970.1 - 0.031 14.1 0.6 0.06 13.1 0.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CCC66970.1 - 0.09 12.3 6.7 0.17 11.4 4.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain MIF4G_like PF09088.6 CCC66971.1 - 3.2e-50 170.2 1.7 7.1e-50 169.0 0.4 2.2 2 0 0 2 2 2 1 MIF4G like MIF4G_like_2 PF09090.6 CCC66971.1 - 1e-19 70.7 3.7 1.1e-18 67.4 2.6 2.3 1 1 0 1 1 1 1 MIF4G like Ribosomal_L15e PF00827.12 CCC66972.1 - 5.9e-89 296.6 14.7 7.3e-89 296.3 10.2 1.1 1 0 0 1 1 1 1 Ribosomal L15 AICARFT_IMPCHas PF01808.13 CCC66973.1 - 1.3e-123 412.0 0.0 2e-123 411.4 0.0 1.2 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CCC66973.1 - 4.4e-24 84.2 0.1 1.4e-23 82.5 0.0 1.9 2 0 0 2 2 2 1 MGS-like domain zf-C3HC4_3 PF13920.1 CCC66974.1 - 1.8e-06 27.5 9.8 3.1e-06 26.7 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC66974.1 - 8.5 6.4 13.6 20 5.3 9.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Aminotran_1_2 PF00155.16 CCC66975.1 - 6.2e-80 268.8 0.0 7.1e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SNARE PF05739.14 CCC66976.1 - 2.1e-18 65.7 3.2 2.1e-18 65.7 2.2 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 CCC66976.1 - 4.9e-18 65.1 1.2 4.9e-18 65.1 0.8 4.1 4 1 0 4 4 4 1 Syntaxin Sed5p PF11416.3 CCC66976.1 - 7.2e-14 50.9 7.6 2.9e-12 45.7 4.3 3.0 2 0 0 2 2 2 1 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 CCC66976.1 - 0.0055 16.5 2.9 0.0055 16.5 2.0 2.3 2 1 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus MCPsignal PF00015.16 CCC66976.1 - 0.0094 15.5 0.1 0.0094 15.5 0.1 3.1 3 1 0 3 3 3 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1664 PF07889.7 CCC66976.1 - 1.4 8.7 7.7 0.45 10.3 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) DUF948 PF06103.6 CCC66976.1 - 2.5 7.9 6.4 9.4 6.1 0.2 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Snf7 PF03357.16 CCC66977.1 - 1.3e-48 164.6 25.2 1.3e-48 164.6 17.4 1.9 1 1 1 2 2 2 1 Snf7 Env-gp36 PF09590.5 CCC66977.1 - 0.0074 14.5 0.6 0.0084 14.3 0.4 1.1 1 0 0 1 1 1 1 Lentivirus surface glycoprotein bZIP_2 PF07716.10 CCC66977.1 - 4.6 7.1 10.1 20 5.0 0.1 3.2 2 1 0 2 2 2 0 Basic region leucine zipper Sdh_cyt PF01127.17 CCC66978.1 - 3.1e-18 65.7 3.3 4.2e-18 65.3 2.3 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Abhydrolase_1 PF00561.15 CCC66979.1 - 1.8e-25 89.8 0.0 3e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 CCC66979.1 - 7.9e-21 73.1 0.0 2e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 CCC66979.1 - 3.9e-05 23.4 0.0 0.00051 19.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCC66979.1 - 0.00018 21.4 0.0 0.00042 20.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 CCC66979.1 - 0.0075 15.7 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 CCC66979.1 - 0.062 12.7 0.1 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pkinase PF00069.20 CCC66980.1 - 4.4e-71 239.0 0.0 7.4e-71 238.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC66980.1 - 5.5e-34 117.4 0.1 8.2e-34 116.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC66980.1 - 7.2e-05 21.8 0.0 0.00014 20.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCC66980.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 CCC66980.1 - 0.028 13.5 0.1 0.074 12.1 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DASH_Hsk3 PF08227.6 CCC66981.1 - 1.3e-15 57.3 2.0 1.5e-15 57.0 1.4 1.1 1 0 0 1 1 1 1 DASH complex subunit Hsk3 like UPF0449 PF15136.1 CCC66981.1 - 0.0083 16.3 0.7 0.011 15.8 0.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0449 Synaptonemal_3 PF15191.1 CCC66981.1 - 0.088 12.5 0.6 0.11 12.2 0.4 1.2 1 0 0 1 1 1 0 Synaptonemal complex central element protein 3 L31 PF09784.4 CCC66982.1 - 1.3e-44 150.4 3.1 1.9e-44 149.9 2.2 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Cmc1 PF08583.5 CCC66983.1 - 9.6e-21 73.3 0.4 1.3e-20 72.9 0.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF1638 PF07796.6 CCC66983.1 - 0.1 12.2 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1638) Adaptin_N PF01602.15 CCC66984.1 - 1.8e-133 445.6 20.1 2.2e-133 445.3 14.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 CCC66984.1 - 3.6e-23 82.3 2.3 3.6e-23 82.3 1.6 3.8 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 CCC66984.1 - 2.1e-14 53.5 0.8 0.00014 22.0 0.0 6.0 3 2 3 6 6 6 2 HEAT repeats HEAT PF02985.17 CCC66984.1 - 5.2e-10 38.5 1.0 0.012 15.5 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat CLASP_N PF12348.3 CCC66984.1 - 8.8e-06 25.2 1.9 1.3 8.2 0.0 4.7 3 1 1 4 4 4 3 CLASP N terminal HEAT_EZ PF13513.1 CCC66984.1 - 0.00013 22.3 0.3 2.8 8.5 0.0 4.5 3 1 0 3 3 3 1 HEAT-like repeat U3snoRNP10 PF12397.3 CCC66984.1 - 0.0034 17.3 2.9 0.15 11.9 0.0 3.6 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 10 WD40 PF00400.27 CCC66985.1 - 3.1e-55 182.2 11.1 9.8e-09 34.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CCC66985.1 - 6.7e-06 25.9 0.6 0.00092 18.9 0.1 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCC66985.1 - 2.8e-05 22.4 5.5 0.11 10.5 0.1 3.8 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCC66985.1 - 0.00054 18.8 0.1 0.59 8.8 0.4 2.9 2 2 0 2 2 2 2 Nup133 N terminal like Peptidase_M3 PF01432.15 CCC66986.1 - 7.8e-131 437.2 0.0 9.6e-131 436.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 CCC66986.1 - 0.098 12.0 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Reprolysin_2 PF13574.1 CCC66986.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Mur_ligase_M PF08245.7 CCC66987.1 - 1.4e-05 25.2 0.0 3.9e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Mur ligase middle domain PCNA_C PF02747.10 CCC66987.1 - 0.051 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Proliferating cell nuclear antigen, C-terminal domain She2p PF11435.3 CCC66988.1 - 6.7e-84 280.3 11.6 8.5e-84 280.0 8.0 1.1 1 0 0 1 1 1 1 RNA binding protein She2p Myosin_head PF00063.16 CCC66989.1 - 9.9e-225 747.6 7.0 1.6e-224 746.9 4.8 1.3 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 CCC66989.1 - 2.2e-48 164.2 0.3 2.2e-47 160.9 0.0 2.3 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 CCC66989.1 - 5e-11 41.8 0.0 9.9e-11 40.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCC66989.1 - 1.9e-08 33.7 0.0 3.9e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCC66989.1 - 1e-06 28.1 0.0 2.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 CCC66989.1 - 0.0052 16.9 0.0 0.014 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCC66989.1 - 0.0055 15.8 0.4 0.041 12.9 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin Hpr_kinase_C PF07475.7 CCC66989.1 - 0.02 14.2 0.0 4.9 6.4 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain NACHT PF05729.7 CCC66989.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_17 PF13207.1 CCC66989.1 - 0.061 14.1 0.0 0.23 12.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCC66989.1 - 0.086 12.6 0.0 0.34 10.7 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 CCC66989.1 - 0.092 12.2 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 CCC66989.1 - 0.094 12.6 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain TPP_enzyme_N PF02776.13 CCC66990.1 - 9.6e-57 191.2 0.2 3.3e-55 186.2 0.0 2.8 4 0 0 4 4 4 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCC66990.1 - 2e-51 173.5 0.0 7.1e-49 165.2 0.0 3.5 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCC66990.1 - 8.3e-36 122.7 0.3 2.9e-35 121.0 0.2 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain His_Phos_1 PF00300.17 CCC66991.1 - 1.2e-18 67.6 0.1 2e-18 66.9 0.1 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PGM_PMM_I PF02878.11 CCC66993.1 - 3.6e-35 120.4 0.5 1e-34 118.9 0.1 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CCC66993.1 - 2.1e-25 88.9 0.0 4e-25 88.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CCC66993.1 - 1.4e-12 47.8 0.0 3.4e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCC66993.1 - 2.6e-09 36.9 0.0 6.3e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Pkinase PF00069.20 CCC66994.1 - 1.5e-69 234.0 0.0 3.9e-69 232.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC66994.1 - 2.3e-30 105.5 0.0 3.6e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCC66994.1 - 1e-10 41.9 0.4 1e-10 41.9 0.3 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCC66994.1 - 0.0046 15.9 0.0 0.011 14.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCC66994.1 - 0.048 12.7 0.1 0.086 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC66994.1 - 0.097 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRN3 PF05327.6 CCC66995.1 - 3.8e-188 626.1 9.1 4.5e-188 625.9 6.3 1.0 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 DUF4404 PF14357.1 CCC66995.1 - 0.2 12.0 7.0 0.36 11.2 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF1539 PF07560.6 CCC66995.1 - 0.39 10.5 5.2 1.7 8.5 1.6 3.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) Daxx PF03344.10 CCC66995.1 - 0.42 9.0 19.3 0.64 8.4 13.4 1.1 1 0 0 1 1 1 0 Daxx Family IncA PF04156.9 CCC66995.1 - 1.9 8.0 5.3 3.8 7.0 3.7 1.4 1 0 0 1 1 1 0 IncA protein SPRY PF00622.23 CCC66996.1 - 5.3e-14 52.3 0.0 1.1e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 SPRY domain SRP9-21 PF05486.7 CCC66997.1 - 2.1e-26 91.4 0.3 4e-26 90.5 0.2 1.4 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) WD40 PF00400.27 CCC66998.1 - 3.3e-25 87.0 11.7 5.7e-07 29.1 0.0 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat Mito_carr PF00153.22 CCC66999.1 - 1.8e-60 200.6 4.5 1.7e-19 69.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Vma12 PF11712.3 CCC67000.1 - 1e-36 125.7 1.1 1.4e-36 125.3 0.7 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Choline_transpo PF04515.7 CCC67000.1 - 0.01 14.6 1.0 0.013 14.2 0.7 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter eIF-5a PF01287.15 CCC67000.1 - 0.1 12.5 1.7 0.45 10.5 0.2 2.4 2 0 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold DUF912 PF06024.7 CCC67000.1 - 5.6 7.0 6.7 0.5 10.4 0.4 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MSV199 PF10553.4 CCC67000.1 - 5.8 6.8 12.5 1.7 8.5 5.6 2.3 2 1 0 2 2 2 0 MSV199 domain DUF3278 PF11683.3 CCC67000.1 - 7.7 6.5 8.2 0.4 10.6 1.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) LpxK PF02606.9 CCC67001.1 - 0.093 11.6 0.3 0.14 11.0 0.2 1.2 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase DUF3304 PF11745.3 CCC67001.1 - 1.8 8.7 5.7 10 6.3 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3304) Pkinase PF00069.20 CCC67002.1 - 3.8e-54 183.5 0.0 5.4e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67002.1 - 1.6e-20 73.2 0.0 1.3e-19 70.3 0.0 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC67002.1 - 0.00035 19.6 0.0 0.00064 18.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like AP_endonuc_2 PF01261.19 CCC67003.1 - 8.4e-30 103.6 0.0 1.1e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Glyco_hydro_16 PF00722.16 CCC67004.1 - 6.3e-21 74.4 2.1 1.4e-20 73.4 1.5 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 BAF1_ABF1 PF04684.8 CCC67005.1 - 1.5e-61 208.7 12.3 2.2e-31 109.2 4.2 2.8 1 1 0 2 2 2 2 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.10 CCC67005.1 - 0.0021 17.6 1.2 0.0045 16.5 0.9 1.6 1 0 0 1 1 1 1 MuDR family transposase KTI12 PF08433.5 CCC67006.1 - 7.4e-91 304.0 0.4 8.6e-91 303.8 0.3 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 CCC67006.1 - 1.8e-07 31.5 0.1 7.4e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCC67006.1 - 4.1e-06 27.5 0.0 2.1e-05 25.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCC67006.1 - 9.1e-06 25.5 0.0 2.2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC67006.1 - 0.00067 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 CCC67006.1 - 0.00086 18.9 0.0 0.0023 17.6 0.0 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 CCC67006.1 - 0.0014 18.8 0.0 0.0076 16.3 0.0 2.3 3 1 0 3 3 2 1 AAA domain AAA PF00004.24 CCC67006.1 - 0.0014 18.8 0.0 0.0038 17.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CPT PF07931.7 CCC67006.1 - 0.0015 18.1 0.0 0.0032 17.1 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein MMR_HSR1 PF01926.18 CCC67006.1 - 0.0092 15.9 0.0 0.22 11.4 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 CCC67006.1 - 0.012 15.3 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 CCC67006.1 - 0.012 14.7 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CCC67006.1 - 0.012 15.4 0.0 0.042 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 CCC67006.1 - 0.013 14.6 0.1 0.027 13.7 0.1 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 CCC67006.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 CCC67006.1 - 0.036 13.7 0.1 0.37 10.4 0.0 2.2 1 1 1 2 2 2 0 NTPase UPF0079 PF02367.12 CCC67006.1 - 0.038 13.6 0.0 0.097 12.3 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 CCC67006.1 - 0.06 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain SRP54 PF00448.17 CCC67006.1 - 0.1 12.0 0.0 0.23 10.8 0.0 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Ground-like PF04155.13 CCC67006.1 - 0.11 12.7 0.4 0.4 11.0 0.3 2.1 1 1 0 1 1 1 0 Ground-like domain RuvB_N PF05496.7 CCC67006.1 - 0.12 11.4 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CCC67006.1 - 0.13 11.9 0.1 0.47 10.0 0.0 2.1 2 1 1 3 3 3 0 NACHT domain Hap4_Hap_bind PF10297.4 CCC67007.1 - 3.3e-06 26.7 4.0 6.7e-06 25.7 2.8 1.5 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 Drc1-Sld2 PF11719.3 CCC67008.1 - 9.2e-51 173.2 34.0 4.6e-49 167.6 23.6 2.1 1 1 0 1 1 1 1 DNA replication and checkpoint protein NAD_binding_10 PF13460.1 CCC67009.1 - 2.7e-19 69.8 0.0 4.1e-19 69.2 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCC67009.1 - 3.3e-06 26.0 0.7 4.7e-06 25.5 0.5 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CCC67009.1 - 0.0025 17.1 0.0 0.072 12.3 0.0 2.8 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 CCC67009.1 - 0.009 15.4 0.1 0.022 14.1 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 CCC67009.1 - 0.11 12.4 0.1 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 CCC67009.1 - 0.14 11.9 0.2 0.21 11.4 0.1 1.2 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain cobW PF02492.14 CCC67010.1 - 3.3e-42 143.9 0.1 5.8e-42 143.1 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 CCC67010.1 - 0.00052 19.6 0.0 0.00093 18.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain AAA_29 PF13555.1 CCC67010.1 - 0.0022 17.4 0.3 0.01 15.3 0.1 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain MobB PF03205.9 CCC67010.1 - 0.0027 17.3 0.0 0.0067 16.1 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CCC67010.1 - 0.0031 17.8 2.0 0.015 15.5 0.5 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCC67010.1 - 0.0036 17.6 0.1 0.0036 17.6 0.1 2.2 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 CCC67010.1 - 0.0058 16.7 0.0 0.27 11.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCC67010.1 - 0.0068 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 CCC67010.1 - 0.0086 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CCC67010.1 - 0.011 15.6 0.0 0.032 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCC67010.1 - 0.015 15.6 0.1 0.038 14.2 0.1 1.7 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 CCC67010.1 - 0.016 14.6 0.3 2.2 7.6 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 CCC67010.1 - 0.033 14.0 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CCC67010.1 - 0.043 14.6 1.2 0.1 13.4 0.3 2.2 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CCC67010.1 - 0.054 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain MMR_HSR1 PF01926.18 CCC67010.1 - 0.069 13.1 0.2 0.24 11.3 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase NACHT PF05729.7 CCC67010.1 - 0.1 12.2 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 CCC67010.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 CCC67010.1 - 0.15 11.7 1.3 0.39 10.4 0.3 2.0 2 0 0 2 2 2 0 NTPase ArgK PF03308.11 CCC67010.1 - 0.16 10.7 2.4 0.51 9.0 0.0 2.6 3 0 0 3 3 3 0 ArgK protein Phos_pyr_kin PF08543.7 CCC67011.1 - 2.5e-12 46.5 0.0 3.4e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 CCC67011.1 - 6.8e-05 22.1 0.0 0.00022 20.4 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase WD40 PF00400.27 CCC67012.1 - 1.4e-06 27.9 2.2 0.0096 15.7 0.1 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CCC67012.1 - 0.0092 14.8 0.9 0.19 10.4 0.0 2.2 1 1 1 2 2 2 2 Coatomer WD associated region RNA_pol_Rpb1_2 PF00623.15 CCC67012.1 - 0.062 13.2 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 2 Ribosomal_L9_N PF01281.14 CCC67014.1 - 1.1e-05 24.5 0.0 3.7e-05 22.8 0.0 1.9 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DUF1189 PF06691.6 CCC67014.1 - 0.061 12.6 0.2 0.074 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Peptidase_M76 PF09768.4 CCC67015.1 - 4.6e-75 250.8 1.8 5.5e-75 250.5 1.3 1.1 1 0 0 1 1 1 1 Peptidase M76 family Tox-MPTase2 PF15638.1 CCC67015.1 - 0.077 12.5 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Metallopeptidase toxin 2 MBOAT PF03062.14 CCC67016.1 - 1.8e-59 201.5 46.8 5.3e-59 199.9 32.4 2.2 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 CCC67016.1 - 0.0021 18.1 3.9 0.0081 16.2 2.7 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family HIG_1_N PF04588.8 CCC67017.1 - 1.1e-06 28.2 1.1 2.4e-06 27.2 0.7 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3169 PF11368.3 CCC67017.1 - 0.0011 18.1 0.0 0.046 12.9 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3169) Tim17 PF02466.14 CCC67018.1 - 3.8e-29 101.3 2.6 4.7e-29 101.0 1.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ATP_Ca_trans_C PF12424.3 CCC67019.1 - 0.47 10.8 0.1 0.47 10.8 0.1 3.2 2 1 1 3 3 3 0 Plasma membrane calcium transporter ATPase C terminal Dus PF01207.12 CCC67020.1 - 3.8e-51 173.7 0.0 8.6e-51 172.5 0.0 1.6 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) SPX PF03105.14 CCC67021.1 - 1.4e-47 162.7 6.4 1.4e-47 162.7 4.5 1.5 2 0 0 2 2 2 1 SPX domain Na_sulph_symp PF00939.14 CCC67021.1 - 6.7e-22 78.0 42.3 8.9e-22 77.5 29.3 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CCC67021.1 - 1.5e-14 53.3 42.0 7.3e-13 47.8 11.9 2.1 1 1 1 2 2 2 2 Citrate transporter Spore_II_R PF09551.5 CCC67021.1 - 0.12 12.4 0.6 0.37 10.8 0.4 1.8 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) PRK PF00485.13 CCC67022.1 - 1.6e-62 210.5 0.0 2.9e-62 209.6 0.0 1.4 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 CCC67022.1 - 1.6e-36 125.4 0.1 2.3e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 CCC67022.1 - 1.6e-09 38.6 0.1 4.2e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCC67022.1 - 7.6e-08 32.7 0.0 2.1e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 CCC67022.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.7 CCC67022.1 - 0.0032 16.5 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 CCC67022.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain CoaE PF01121.15 CCC67022.1 - 0.52 9.6 4.0 8.2 5.7 0.5 3.1 3 1 0 3 3 3 0 Dephospho-CoA kinase HA2 PF04408.18 CCC67023.1 - 1e-17 63.9 0.0 3.9e-17 62.1 0.0 2.0 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCC67023.1 - 1.8e-15 56.7 0.0 4.6e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCC67023.1 - 2e-13 49.9 0.0 5.3e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCC67023.1 - 3.1e-08 33.2 1.6 4.2e-08 32.8 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCC67023.1 - 0.00014 22.0 0.0 0.00053 20.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCC67023.1 - 0.00078 19.3 1.7 0.071 13.0 0.3 3.9 3 1 0 3 3 3 1 AAA domain T2SE PF00437.15 CCC67023.1 - 0.0013 17.7 0.0 0.005 15.7 0.0 1.9 2 0 0 2 2 2 1 Type II/IV secretion system protein ABC_tran PF00005.22 CCC67023.1 - 0.0054 17.0 4.2 0.0054 17.0 0.1 2.9 3 1 0 3 3 3 1 ABC transporter KaiC PF06745.8 CCC67023.1 - 0.0092 15.1 0.0 0.022 13.8 0.0 1.6 1 0 0 1 1 1 1 KaiC NB-ARC PF00931.17 CCC67023.1 - 0.0096 14.8 0.0 0.035 12.9 0.0 2.0 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.1 CCC67023.1 - 0.014 15.0 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 CCC67023.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.1 CCC67023.1 - 0.059 13.1 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_29 PF13555.1 CCC67023.1 - 0.075 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Helicase_RecD PF05127.9 CCC67023.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Helicase Glyoxalase PF00903.20 CCC67024.1 - 2.7e-35 121.1 0.1 5.7e-19 68.3 0.0 2.1 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 CCC67024.1 - 4.4e-25 88.3 0.0 9e-13 48.7 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 CCC67024.1 - 4.3e-11 42.7 0.0 0.00021 21.2 0.0 3.3 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 CCC67024.1 - 0.0028 17.3 0.3 2.8 7.6 0.1 2.4 2 0 0 2 2 2 2 CppA N-terminal Med9 PF07544.8 CCC67025.1 - 3.4e-21 74.7 0.2 3.4e-21 74.7 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Avl9 PF09794.4 CCC67025.1 - 0.019 13.5 0.0 0.029 12.8 0.0 1.3 1 0 0 1 1 1 0 Transport protein Avl9 NBP1 PF08537.5 CCC67025.1 - 0.063 12.4 4.8 0.091 11.9 3.3 1.5 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 RBFA PF02033.13 CCC67025.1 - 0.094 12.7 0.1 0.21 11.6 0.0 1.8 2 1 0 2 2 2 0 Ribosome-binding factor A DUF1227 PF06777.6 CCC67025.1 - 0.13 11.9 2.1 0.55 9.9 1.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1227) Cortex-I_coil PF09304.5 CCC67025.1 - 2.5 8.1 6.0 0.24 11.4 1.0 1.6 2 0 0 2 2 2 0 Cortexillin I, coiled coil zf-RING_2 PF13639.1 CCC67026.1 - 8.9e-13 47.8 9.8 2e-12 46.7 6.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCC67026.1 - 1.9e-11 43.9 7.4 3.8e-11 42.9 5.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CCC67026.1 - 1.5e-05 24.9 13.4 1.7e-05 24.7 7.8 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCC67026.1 - 6.4e-05 22.7 7.7 0.00061 19.5 5.4 2.2 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CCC67026.1 - 0.0002 20.9 9.6 0.0002 20.9 6.6 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC67026.1 - 0.0012 18.5 12.4 0.0022 17.6 7.4 2.1 1 1 1 2 2 2 2 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCC67026.1 - 0.0016 18.0 12.6 0.0095 15.5 7.6 2.2 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CCC67026.1 - 0.006 16.5 8.2 0.019 14.9 5.3 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain PHD PF00628.24 CCC67026.1 - 0.021 14.5 7.7 0.041 13.5 5.3 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 CCC67026.1 - 0.11 12.2 5.4 0.47 10.2 3.8 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 CCC67026.1 - 0.18 11.3 10.1 0.97 8.9 2.8 2.3 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.1 CCC67026.1 - 0.46 10.0 9.4 2.4 7.8 1.7 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Whi5 PF08528.6 CCC67027.1 - 1.3e-07 31.0 1.4 2.9e-07 29.8 1.0 1.7 1 0 0 1 1 1 1 Whi5 like PID_2 PF14719.1 CCC67027.1 - 0.00079 19.1 0.9 0.0014 18.3 0.6 1.3 1 0 0 1 1 1 1 Phosphotyrosine interaction domain (PTB/PID) DNA_primase_lrg PF04104.9 CCC67028.1 - 2e-88 296.0 0.3 2.9e-88 295.4 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit KilA-N PF04383.8 CCC67029.1 - 7.1e-05 22.3 0.1 0.00073 19.1 0.0 2.5 2 1 0 2 2 2 1 KilA-N domain Spc42p PF11544.3 CCC67030.1 - 3.1e-11 43.0 9.5 3.1e-11 43.0 6.6 3.6 2 2 2 4 4 4 1 Spindle pole body component Spc42p DivIVA PF05103.8 CCC67030.1 - 0.27 11.3 11.1 0.16 12.0 1.0 2.8 2 1 1 3 3 3 0 DivIVA protein DUF4407 PF14362.1 CCC67030.1 - 3.2 6.6 7.7 3 6.7 4.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Snf7 PF03357.16 CCC67031.1 - 1.3e-32 112.5 18.1 1.3e-32 112.5 12.5 1.9 2 0 0 2 2 2 1 Snf7 Eno-Rase_FAD_bd PF07055.7 CCC67031.1 - 0.0059 16.5 1.3 0.0059 16.5 0.9 2.3 2 0 0 2 2 2 1 Enoyl reductase FAD binding domain LAGLIDADG_2 PF03161.8 CCC67031.1 - 0.098 12.5 2.4 0.078 12.8 0.7 1.5 2 0 0 2 2 2 0 LAGLIDADG DNA endonuclease family Lyase_8_N PF08124.6 CCC67031.1 - 0.67 8.7 9.2 0.052 12.4 2.9 1.6 2 1 0 2 2 2 0 Polysaccharide lyase family 8, N terminal alpha-helical domain Prominin PF05478.6 CCC67031.1 - 5.9 4.3 14.3 7.1 4.0 9.9 1.1 1 0 0 1 1 1 0 Prominin PP2C_C PF07830.8 CCC67031.1 - 7.9 6.6 8.6 1.8 8.7 1.2 3.0 2 1 1 4 4 4 0 Protein serine/threonine phosphatase 2C, C-terminal domain Lung_7-TM_R PF06814.8 CCC67032.1 - 3.2e-85 285.6 23.5 4.2e-85 285.2 16.3 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor EVI2A PF05399.6 CCC67032.1 - 0.041 13.1 2.2 0.75 9.0 0.2 2.7 3 0 0 3 3 3 0 Ectropic viral integration site 2A protein (EVI2A) UbiA PF01040.13 CCC67032.1 - 0.97 8.6 19.9 3.6 6.7 3.6 2.9 2 1 1 3 3 3 0 UbiA prenyltransferase family YajC PF02699.10 CCC67032.1 - 3.1 7.5 7.2 0.63 9.7 1.1 2.6 2 0 0 2 2 2 0 Preprotein translocase subunit DUF4117 PF13491.1 CCC67032.1 - 3.8 6.9 8.5 0.25 10.7 1.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4117) Zn_clus PF00172.13 CCC67033.1 - 3.4e-10 39.6 12.4 5.5e-10 38.9 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-RING_2 PF13639.1 CCC67034.1 - 5.8e-11 42.0 5.2 1.1e-10 41.1 3.6 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCC67034.1 - 1.4e-08 34.6 4.8 2.8e-08 33.7 3.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CCC67034.1 - 5.6e-08 32.3 3.8 9.3e-08 31.6 2.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCC67034.1 - 2.4e-06 27.0 3.3 4.6e-06 26.1 2.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCC67034.1 - 5.1e-05 22.8 6.0 0.0001 21.9 4.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC67034.1 - 0.00014 21.7 4.9 0.00072 19.5 3.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCC67034.1 - 0.00079 19.2 1.8 0.0017 18.1 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 CCC67034.1 - 0.00081 19.1 0.2 0.0019 17.9 0.2 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 CCC67034.1 - 0.0083 15.8 0.9 0.024 14.3 0.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 CCC67034.1 - 0.1 12.5 5.0 0.32 10.9 3.5 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain HAD_2 PF13419.1 CCC67035.1 - 1.2e-17 64.7 0.0 1.4e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC67035.1 - 3.8e-06 27.4 0.0 4.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCC67035.1 - 0.012 15.2 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like Hydrolase_6 PF13344.1 CCC67035.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase HAD PF12710.2 CCC67035.1 - 0.044 13.9 0.0 0.047 13.8 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase CDC45 PF02724.9 CCC67036.1 - 0.062 11.3 8.9 0.12 10.3 6.1 1.4 1 0 0 1 1 1 0 CDC45-like protein HMG_box PF00505.14 CCC67037.1 - 1.4e-35 121.3 9.5 8.8e-19 67.5 1.3 3.0 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CCC67037.1 - 5.1e-17 62.0 13.6 5.4e-11 42.7 0.6 3.5 3 0 0 3 3 3 2 HMG-box domain CHDNT PF08073.7 CCC67037.1 - 2.7e-07 30.1 0.0 0.0002 20.9 0.0 2.6 2 0 0 2 2 2 2 CHDNT (NUC034) domain Ribosomal_60s PF00428.14 CCC67037.1 - 0.21 12.0 3.3 0.48 10.8 2.3 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-C2H2 PF00096.21 CCC67038.1 - 0.0007 19.7 4.9 0.0007 19.7 3.4 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC67038.1 - 0.0046 17.2 17.6 0.0081 16.4 3.5 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-CCHC_2 PF13696.1 CCC67038.1 - 0.06 12.8 0.1 0.06 12.8 0.0 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-Di19 PF05605.7 CCC67038.1 - 0.16 12.1 7.2 0.32 11.1 5.0 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 CCC67038.1 - 3 8.3 13.1 2.6 8.4 3.2 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Malic_M PF03949.10 CCC67039.1 - 3.5e-77 259.4 0.0 5e-77 258.9 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 CCC67039.1 - 2.3e-64 216.3 0.0 4.5e-64 215.3 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Shikimate_DH PF01488.15 CCC67039.1 - 0.0004 20.4 0.5 2.8 8.0 0.0 3.6 4 0 0 4 4 4 2 Shikimate / quinate 5-dehydrogenase TFIIE_alpha PF02002.12 CCC67040.1 - 2.9e-33 113.5 0.0 2.9e-33 113.5 0.0 2.6 3 0 0 3 3 3 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 CCC67040.1 - 1.6e-11 43.3 0.5 5.4e-11 41.6 0.3 2.0 1 0 0 1 1 1 1 TFIIB zinc-binding Neur_chan_memb PF02932.11 CCC67040.1 - 3 7.6 8.9 3 7.6 3.5 2.5 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region GalP_UDP_transf PF01087.17 CCC67040.1 - 4.9 7.1 11.3 6.7 6.7 1.8 3.1 2 1 1 3 3 3 0 Galactose-1-phosphate uridyl transferase, N-terminal domain ThiF PF00899.16 CCC67041.1 - 2.3e-36 124.6 0.1 3.5e-36 124.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CCC67041.1 - 0.00017 21.7 0.1 0.00033 20.7 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 CCC67041.1 - 0.009 16.0 0.4 0.027 14.4 0.0 2.0 3 0 0 3 3 3 1 TrkA-N domain Saccharop_dh PF03435.13 CCC67041.1 - 0.012 14.5 0.3 0.016 14.1 0.2 1.3 1 1 0 1 1 1 0 Saccharopine dehydrogenase ApbA PF02558.11 CCC67041.1 - 0.023 14.1 0.1 0.047 13.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 CCC67041.1 - 0.088 12.1 0.2 0.19 11.1 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3Beta_HSD PF01073.14 CCC67041.1 - 0.14 10.8 0.2 0.26 9.9 0.1 1.5 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DAO PF01266.19 CCC67041.1 - 0.16 10.8 0.1 0.53 9.1 0.1 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Mito_carr PF00153.22 CCC67042.1 - 4.4e-64 212.2 3.1 4.8e-23 80.6 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 CCC67042.1 - 0.013 15.5 0.3 2.1 8.4 0.0 3.0 2 1 2 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family DUF2370 PF10176.4 CCC67043.1 - 3.6e-79 265.4 0.0 3.6e-79 265.4 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2370) SNF5 PF04855.7 CCC67044.1 - 5.6e-67 225.7 1.5 5.6e-67 225.7 1.1 4.0 3 1 0 3 3 3 2 SNF5 / SMARCB1 / INI1 Adap_comp_sub PF00928.16 CCC67045.1 - 3.9e-32 111.3 0.0 9.6e-32 110.1 0.0 1.6 1 1 0 1 1 1 1 Adaptor complexes medium subunit family adh_short PF00106.20 CCC67046.1 - 2.6e-66 222.6 1.4 1.4e-32 112.8 0.5 2.4 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 CCC67046.1 - 7.6e-33 113.6 0.1 5.7e-16 58.7 0.1 2.4 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 CCC67046.1 - 4.6e-31 106.7 0.0 9e-31 105.8 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 CCC67046.1 - 9.3e-07 28.7 0.0 3.7e-06 26.7 0.0 2.0 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase 3HCDH_N PF02737.13 CCC67046.1 - 0.06 12.9 1.7 4.1 7.0 0.0 2.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain QCR10 PF09796.4 CCC67047.1 - 2.2e-27 94.4 0.1 2.5e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 CCC67047.1 - 0.016 14.8 0.1 0.023 14.4 0.1 1.3 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Bromodomain PF00439.20 CCC67048.1 - 1.3e-31 108.3 4.5 6.5e-19 67.6 0.1 3.2 3 0 0 3 3 3 2 Bromodomain LAMTOR PF15454.1 CCC67049.1 - 5.1e-12 45.8 0.2 5.1e-12 45.8 0.2 2.0 2 1 0 2 2 2 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF2255 PF10012.4 CCC67049.1 - 0.029 14.3 0.1 0.055 13.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2255) Pilus_CpaD PF09476.5 CCC67049.1 - 0.073 12.5 0.2 0.14 11.6 0.1 1.5 1 0 0 1 1 1 0 Pilus biogenesis CpaD protein (pilus_cpaD) DUF655 PF04919.7 CCC67049.1 - 0.15 11.7 0.7 0.2 11.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF655) DUF2733 PF10813.3 CCC67049.1 - 0.2 11.2 0.3 0.2 11.2 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) Ribosomal_L50 PF10501.4 CCC67050.1 - 7.3e-21 74.2 0.7 2e-20 72.7 0.2 2.0 2 0 0 2 2 2 1 Ribosomal subunit 39S KilA-N PF04383.8 CCC67050.1 - 0.022 14.3 0.2 0.022 14.3 0.1 1.8 2 0 0 2 2 2 0 KilA-N domain Ca_chan_IQ PF08763.6 CCC67050.1 - 0.17 11.1 0.0 0.17 11.1 0.0 2.1 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain V1R PF03402.9 CCC67051.1 - 0.49 9.7 4.5 0.083 12.2 0.5 1.6 2 0 0 2 2 2 0 Vomeronasal organ pheromone receptor family, V1R PPTA PF01239.17 CCC67052.1 - 0.00042 19.5 0.6 0.0024 17.1 0.4 2.5 1 0 0 1 1 1 1 Protein prenyltransferase alpha subunit repeat Oxysterol_BP PF01237.13 CCC67053.1 - 5.6e-88 294.8 0.0 7.2e-88 294.4 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein PAP_central PF04928.12 CCC67054.1 - 1.4e-107 358.2 0.0 2.8e-107 357.2 0.0 1.5 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 CCC67054.1 - 3.4e-47 159.8 3.6 6e-47 159.0 2.5 1.4 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 CCC67054.1 - 3e-11 43.4 0.1 1.1e-10 41.7 0.1 1.9 1 0 0 1 1 1 1 Nucleotidyltransferase domain Dynamin_M PF01031.15 CCC67055.1 - 6.2e-108 360.0 0.1 6.2e-108 360.0 0.1 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 CCC67055.1 - 1.1e-55 188.0 0.3 3.1e-55 186.5 0.2 1.8 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 CCC67055.1 - 3.1e-24 84.6 2.2 8.6e-24 83.2 1.5 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 CCC67055.1 - 0.0012 18.7 0.7 0.029 14.3 0.5 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCC67055.1 - 0.012 16.0 0.0 0.032 14.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein PSD4 PF07631.6 CCC67055.1 - 0.039 14.3 0.3 0.25 11.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1592) APS_kinase PF01583.15 CCC67056.1 - 1.3e-74 249.0 0.0 1.6e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CCC67056.1 - 7.3e-09 35.6 0.0 1.4e-08 34.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCC67056.1 - 2.4e-05 25.1 0.1 3.5e-05 24.6 0.1 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCC67056.1 - 0.0001 21.6 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 CCC67056.1 - 0.00047 19.6 0.0 0.00075 18.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 CCC67056.1 - 0.00099 19.4 0.1 0.0022 18.3 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CCC67056.1 - 0.02 15.1 0.2 0.023 15.0 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 CCC67056.1 - 0.031 14.2 0.1 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 CCC67056.1 - 0.075 13.3 0.0 0.095 12.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter CbiA PF01656.18 CCC67056.1 - 0.078 12.3 0.1 0.08 12.3 0.0 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CPT PF07931.7 CCC67056.1 - 0.2 11.2 0.3 3 7.4 0.0 2.3 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Snf7 PF03357.16 CCC67057.1 - 1e-32 112.8 25.7 7.1e-32 110.1 16.9 2.0 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.9 CCC67057.1 - 2.4e-06 27.0 8.0 3.4e-06 26.5 5.5 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Hpt PF01627.18 CCC67057.1 - 0.012 15.6 2.8 0.016 15.1 0.2 2.3 2 0 0 2 2 2 0 Hpt domain DUF885 PF05960.6 CCC67057.1 - 0.03 13.4 7.0 0.035 13.2 4.8 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Pollen_allerg_2 PF01620.11 CCC67057.1 - 0.15 12.3 1.1 0.23 11.7 0.7 1.3 1 0 0 1 1 1 0 Ribonuclease (pollen allergen) Clathrin_H_link PF13838.1 CCC67057.1 - 0.16 11.8 1.3 0.31 10.9 0.9 1.5 1 0 0 1 1 1 0 Clathrin-H-link DUF87 PF01935.12 CCC67057.1 - 0.42 10.3 10.3 0.46 10.2 0.1 2.1 1 1 0 2 2 2 0 Domain of unknown function DUF87 YlqD PF11068.3 CCC67057.1 - 5.9 6.9 22.4 2 8.4 10.1 2.4 1 1 1 2 2 2 0 YlqD protein PITH PF06201.8 CCC67058.1 - 3.3e-31 108.1 0.1 4.4e-31 107.7 0.1 1.2 1 0 0 1 1 1 1 PITH domain bZIP_1 PF00170.16 CCC67060.1 - 6.6e-06 25.9 18.6 7.6e-06 25.8 12.3 1.6 1 1 0 1 1 1 1 bZIP transcription factor DUF327 PF03885.8 CCC67060.1 - 0.0071 16.1 7.1 0.013 15.3 4.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF327) Macoilin PF09726.4 CCC67060.1 - 0.022 13.0 9.6 0.026 12.8 6.7 1.1 1 0 0 1 1 1 0 Transmembrane protein SprA-related PF12118.3 CCC67060.1 - 0.054 12.8 7.9 0.088 12.1 5.4 1.3 1 0 0 1 1 1 0 SprA-related family Glutaredoxin2_C PF04399.8 CCC67060.1 - 0.059 12.9 5.2 0.11 12.0 3.6 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain DUF722 PF05263.6 CCC67060.1 - 0.13 12.3 4.8 0.21 11.7 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Ndc1_Nup PF09531.5 CCC67060.1 - 0.49 8.7 6.7 0.54 8.6 4.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup APG6 PF04111.7 CCC67060.1 - 0.49 9.3 11.8 0.68 8.9 8.2 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SOBP PF15279.1 CCC67060.1 - 1.1 9.6 9.5 1.3 9.2 6.6 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein IncA PF04156.9 CCC67060.1 - 1.3 8.6 9.0 2 7.9 6.2 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 CCC67060.1 - 1.9 6.2 7.9 2.5 5.8 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Smr PF01713.16 CCC67061.1 - 1.4e-11 44.4 0.0 3.2e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 CCC67061.1 - 1.5e-11 43.5 0.4 3.7e-06 26.3 0.2 3.5 3 0 0 3 3 3 2 CUE domain CENP-C_C PF11699.3 CCC67062.1 - 1.2e-28 98.8 3.4 2.5e-28 97.8 2.4 1.6 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 CCC67062.1 - 3.3e-20 73.0 3.2 3.3e-20 73.0 2.2 3.4 3 1 0 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 CCC67062.1 - 5.9e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Pkinase PF00069.20 CCC67063.1 - 1.7e-71 240.4 0.0 3e-71 239.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67063.1 - 3.1e-46 157.5 0.0 5.4e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CCC67063.1 - 6.9e-22 77.6 0.0 6.9e-22 77.6 0.0 3.1 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 CCC67063.1 - 0.00024 20.1 0.0 0.00048 19.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCC67063.1 - 0.2 11.3 0.0 1.1 8.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family HECT PF00632.20 CCC67064.1 - 4.1e-76 256.1 0.3 7.6e-76 255.2 0.2 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Sigma70_ner PF04546.8 CCC67064.1 - 0.56 9.7 10.5 1.4 8.4 3.5 2.6 2 0 0 2 2 2 0 Sigma-70, non-essential region JCAD PF15351.1 CCC67064.1 - 0.66 7.5 1.4 0.91 7.0 1.0 1.0 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease TRAM_LAG1_CLN8 PF03798.11 CCC67065.1 - 7.8e-35 120.2 24.5 7.8e-35 120.2 17.0 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CCC67065.1 - 5.1e-22 77.1 0.8 1.4e-21 75.7 0.6 1.8 1 0 0 1 1 1 1 TRAM1-like protein Herpes_LMP1 PF05297.6 CCC67065.1 - 6.8 5.5 8.1 12 4.7 5.6 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) VHS PF00790.14 CCC67066.1 - 9.2e-34 116.0 3.8 9.2e-34 116.0 2.6 2.1 3 0 0 3 3 3 1 VHS domain SH3_9 PF14604.1 CCC67066.1 - 1.4e-15 56.6 0.1 2.3e-15 55.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCC67066.1 - 5.1e-14 51.3 0.0 1.1e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCC67066.1 - 5.9e-11 41.6 0.0 3.1e-10 39.4 0.0 2.1 2 0 0 2 2 2 1 Variant SH3 domain SNF2_N PF00176.18 CCC67069.1 - 1.8e-70 237.1 0.0 2.8e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 CCC67069.1 - 5.6e-54 182.9 6.4 1.3e-53 181.7 4.0 1.8 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 CCC67069.1 - 7.6e-14 51.3 0.0 2.9e-13 49.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 CCC67069.1 - 1.8e-08 33.5 0.2 1.8e-08 33.5 0.1 3.9 3 3 1 4 4 4 1 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 CCC67069.1 - 4.3e-05 23.0 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1170 PF06663.8 CCC67069.1 - 0.0084 16.0 0.4 0.067 13.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1170) ResIII PF04851.10 CCC67069.1 - 0.01 15.6 0.0 0.045 13.5 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit MRP-S31 PF15433.1 CCC67069.1 - 0.59 9.5 4.9 0.085 12.2 0.1 1.9 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Ran-binding PF05508.6 CCC67070.1 - 2.8e-115 384.4 3.9 4.1e-115 383.8 2.7 1.2 1 0 0 1 1 1 1 RanGTP-binding protein RBD-FIP PF09457.5 CCC67070.1 - 0.025 14.3 0.2 0.025 14.3 0.1 2.5 3 0 0 3 3 3 0 FIP domain Syntaxin PF00804.20 CCC67070.1 - 2.3 8.4 18.4 0.069 13.3 0.7 3.6 4 1 0 4 4 4 0 Syntaxin Copper-fist PF00649.13 CCC67071.1 - 1.8e-20 71.8 0.8 1.8e-20 71.8 0.6 2.3 1 1 1 2 2 2 2 Copper fist DNA binding domain Cullin PF00888.17 CCC67072.1 - 1.4e-92 311.1 22.5 1.4e-92 311.1 15.6 1.8 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 CCC67072.1 - 1.5e-16 59.9 5.2 1.8e-16 59.6 0.8 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain Pex24p PF06398.6 CCC67073.1 - 4e-84 282.4 9.9 5.1e-84 282.1 6.9 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin LTXXQ PF07813.7 CCC67073.1 - 0.07 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 LTXXQ motif family protein Ribosomal_L38e PF01781.13 CCC67074.1 - 7.4e-28 96.1 3.2 8.3e-28 95.9 2.2 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family PapD_C PF02753.12 CCC67074.1 - 0.082 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Pili assembly chaperone PapD, C-terminal domain TFIIF_beta PF02270.10 CCC67075.1 - 2.1e-94 316.3 15.9 3.5e-94 315.6 11.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit OmpH PF03938.9 CCC67075.1 - 2.3 8.1 15.8 0.097 12.6 3.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Prp18 PF02840.10 CCC67076.1 - 1.3e-40 138.5 0.3 1.3e-40 138.5 0.2 2.0 2 0 0 2 2 2 1 Prp18 domain CTP_transf_2 PF01467.21 CCC67077.1 - 3.8e-21 75.7 0.1 7.5e-13 48.8 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 CCC67077.1 - 4.7e-06 26.3 0.1 0.066 12.8 0.0 3.3 3 1 0 3 3 3 2 FAD synthetase Fiji_64_capsid PF05880.6 CCC67077.1 - 0.037 12.3 0.0 0.057 11.7 0.0 1.3 1 0 0 1 1 1 0 Fijivirus 64 kDa capsid protein N6-adenineMlase PF10237.4 CCC67078.1 - 3.3e-61 205.6 0.0 4.6e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase SGS PF05002.10 CCC67078.1 - 0.052 13.2 0.9 0.12 12.1 0.6 1.6 1 0 0 1 1 1 0 SGS domain 3Beta_HSD PF01073.14 CCC67079.1 - 5e-86 287.8 0.0 6.1e-86 287.5 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCC67079.1 - 4.6e-26 91.7 0.0 5.9e-26 91.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCC67079.1 - 5.1e-13 48.5 0.0 2.2e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 CCC67079.1 - 7.3e-11 41.4 0.0 1.2e-10 40.7 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 CCC67079.1 - 1e-09 38.7 0.0 1.4e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CCC67079.1 - 1.2e-07 31.0 0.0 2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 CCC67079.1 - 0.002 18.0 0.0 0.0059 16.5 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCC67079.1 - 0.014 15.0 0.0 0.057 13.0 0.0 1.8 1 1 0 1 1 1 0 KR domain PALP PF00291.20 CCC67080.1 - 6.6e-60 202.9 0.2 7.8e-60 202.6 0.2 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Abhydrolase_6 PF12697.2 CCC67082.1 - 1.1e-20 74.5 0.0 1.5e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCC67082.1 - 3.9e-11 42.8 0.0 5.6e-11 42.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC67082.1 - 4.9e-10 39.3 0.0 9.6e-10 38.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CCC67082.1 - 3.6e-06 26.7 0.0 1.5e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.3 CCC67082.1 - 4.6e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 CCC67082.1 - 0.00033 20.9 0.0 0.00047 20.4 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 CCC67082.1 - 0.015 14.9 0.0 0.025 14.1 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 CCC67082.1 - 0.022 14.3 0.0 0.03 13.9 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold CutA1 PF03091.10 CCC67083.1 - 0.0064 16.1 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein DUF2721 PF11026.3 CCC67083.1 - 0.017 14.7 0.1 2.8 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) CTP_transf_1 PF01148.15 CCC67083.1 - 0.019 14.5 5.8 0.028 14.0 4.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase family MFS_1 PF07690.11 CCC67083.1 - 2.2 6.9 6.6 1.2 7.7 0.1 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily Iron_permease PF04120.7 CCC67085.1 - 9.8e-26 89.9 25.4 2.5e-16 59.4 0.9 5.3 5 0 0 5 5 5 4 Low affinity iron permease FliD_N PF02465.13 CCC67085.1 - 1.7 9.0 6.3 0.29 11.5 1.4 1.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF572 PF04502.8 CCC67086.1 - 2.6e-51 174.7 18.6 3.5e-51 174.3 12.9 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) DDE_Tnp_IS1 PF03400.8 CCC67086.1 - 0.053 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 IS1 transposase zf-FPG_IleRS PF06827.9 CCC67086.1 - 0.067 12.8 3.2 0.21 11.2 0.5 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Mu-like_Com PF10122.4 CCC67086.1 - 0.074 12.1 1.4 0.11 11.5 0.1 2.0 2 0 0 2 2 2 0 Mu-like prophage protein Com zinc_ribbon_5 PF13719.1 CCC67086.1 - 0.089 12.3 0.4 0.36 10.4 0.0 2.1 2 0 0 2 2 2 0 zinc-ribbon domain PA26 PF04636.8 CCC67086.1 - 1.4 7.5 5.7 2.2 6.8 3.9 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) TF_Zn_Ribbon PF08271.7 CCC67086.1 - 1.6 8.1 3.9 0.35 10.2 0.1 1.8 2 0 0 2 2 2 0 TFIIB zinc-binding RVT_1 PF00078.22 CCC67087.1 - 8.9e-20 70.9 0.5 2e-19 69.8 0.4 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCC67087.1 - 3.9e-19 68.9 0.0 1e-18 67.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CCC67087.1 - 0.0016 17.7 0.1 0.0043 16.4 0.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Abhydrolase_1 PF00561.15 CCC67090.1 - 7.8e-21 74.6 0.0 1.2e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCC67090.1 - 3.7e-17 62.4 0.0 5.6e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCC67090.1 - 1.5e-15 57.6 0.0 2.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 CCC67090.1 - 1.1e-08 34.7 0.1 3e-08 33.3 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase DLH PF01738.13 CCC67090.1 - 0.00034 19.9 0.2 0.0079 15.5 0.0 2.3 2 1 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 CCC67090.1 - 0.0049 16.3 0.0 0.9 8.9 0.0 2.8 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 CCC67090.1 - 0.0068 15.6 1.0 0.021 14.0 0.0 2.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family Mlp PF03304.8 CCC67090.1 - 0.094 12.7 0.1 0.17 11.9 0.1 1.3 1 0 0 1 1 1 0 Mlp lipoprotein family RasGAP PF00616.14 CCC67092.1 - 1.8e-45 155.0 8.6 6.3e-45 153.2 5.9 2.0 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 CCC67092.1 - 0.0061 16.3 0.1 0.017 14.9 0.1 1.8 1 0 0 1 1 1 1 C2 domain Snf7 PF03357.16 CCC67093.1 - 5.3e-34 117.0 8.9 6.5e-34 116.7 6.2 1.1 1 0 0 1 1 1 1 Snf7 JHBP PF06585.6 CCC67093.1 - 0.043 12.6 0.8 0.067 12.0 0.5 1.3 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) DUF3216 PF11505.3 CCC67093.1 - 0.12 12.2 1.9 0.13 12.0 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) Mit_KHE1 PF10173.4 CCC67093.1 - 0.16 11.8 3.0 1.6 8.5 2.1 2.1 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Trypan_PARP PF05887.6 CCC67093.1 - 0.22 11.3 6.2 0.34 10.7 4.3 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Glyco_transf_22 PF03901.12 CCC67094.1 - 3.1e-28 98.9 25.0 3.9e-28 98.6 17.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Pkinase PF00069.20 CCC67095.1 - 1.2e-64 217.9 0.0 2.3e-64 217.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67095.1 - 2.5e-36 125.0 0.0 7.2e-36 123.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC67095.1 - 2.3e-07 30.0 2.7 3e-07 29.6 0.0 2.5 3 1 0 3 3 3 1 Kinase-like APH PF01636.18 CCC67095.1 - 0.063 12.9 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Metallophos PF00149.23 CCC67096.1 - 4.3e-41 140.5 0.6 6.4e-41 139.9 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ubiquitin PF00240.18 CCC67097.1 - 1.2e-08 34.2 0.6 1.4e-08 33.9 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCC67097.1 - 0.00016 21.3 0.3 0.00017 21.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CC2D2AN-C2 PF15625.1 CCC67097.1 - 0.019 14.4 0.0 0.023 14.1 0.0 1.1 1 0 0 1 1 1 0 CC2D2A N-terminal C2 domain Ubiquitin_2 PF14560.1 CCC67097.1 - 0.022 14.9 0.4 0.11 12.8 0.3 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain Chorismate_bind PF00425.13 CCC67098.1 - 8.3e-68 228.4 0.0 1.2e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 CCC67098.1 - 6.8e-30 103.9 0.0 1e-29 103.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 CCC67098.1 - 3.5e-14 52.9 0.0 9.9e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 CCC67098.1 - 1.4e-06 27.9 0.0 2.4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 Glucosamine_iso PF01182.15 CCC67099.1 - 2.8e-49 167.5 0.0 4.1e-49 166.9 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase LMBR1 PF04791.11 CCC67100.1 - 1.1e-10 40.7 26.8 8.5e-10 37.7 18.6 2.0 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF3215 PF11503.3 CCC67102.1 - 2.3e-12 46.3 0.0 2.8e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) CobW_C PF07683.9 CCC67102.1 - 0.053 13.2 0.0 0.53 10.0 0.0 2.6 1 1 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Ribosom_S12_S23 PF00164.20 CCC67103.1 - 2.7e-36 123.6 0.4 3e-36 123.5 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Ribosomal_S19 PF00203.16 CCC67104.1 - 3.9e-23 80.8 0.0 4.9e-23 80.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 DEAD PF00270.24 CCC67105.1 - 4.3e-39 133.7 0.9 1e-38 132.4 0.6 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC67105.1 - 5e-18 64.7 0.2 1e-17 63.7 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC67105.1 - 1.3e-06 28.4 0.1 1.3e-06 28.4 0.1 3.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCC67105.1 - 0.00011 21.1 3.6 0.00013 20.8 0.1 2.4 2 1 0 3 3 3 1 SNF2 family N-terminal domain Flavi_DEAD PF07652.9 CCC67105.1 - 0.003 17.3 0.2 0.037 13.7 0.0 2.5 1 1 1 2 2 2 1 Flavivirus DEAD domain AAA_22 PF13401.1 CCC67105.1 - 0.12 12.5 1.2 0.67 10.1 0.8 2.3 1 1 0 1 1 1 0 AAA domain Cation_efflux PF01545.16 CCC67106.1 - 5.2e-06 25.7 11.2 1.2e-05 24.5 7.5 1.8 2 1 0 2 2 2 1 Cation efflux family UbiA PF01040.13 CCC67108.1 - 7.8e-31 107.2 19.8 1e-30 106.8 13.7 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family GHMP_kinases_N PF00288.21 CCC67109.1 - 1.4e-10 41.0 1.5 5.1e-10 39.2 1.0 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF1819 PF08849.6 CCC67109.1 - 0.039 13.3 0.0 0.089 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative inner membrane protein (DUF1819) DNA_primase_S PF01896.14 CCC67109.1 - 0.046 13.5 0.1 0.17 11.7 0.0 1.9 2 1 0 2 2 2 0 Eukaryotic and archaeal DNA primase small subunit WD40 PF00400.27 CCC67110.1 - 7.1e-65 212.7 11.4 9.2e-11 41.1 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CCC67110.1 - 4e-25 87.8 14.0 4e-25 87.8 9.7 2.3 2 0 0 2 2 2 1 Tup N-terminal Nup160 PF11715.3 CCC67110.1 - 0.00025 19.3 4.1 0.17 9.9 0.1 3.7 1 1 2 3 3 3 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCC67110.1 - 0.00029 19.7 5.6 0.0049 15.6 0.1 3.8 2 1 0 3 3 3 1 Nup133 N terminal like DUF3810 PF12725.2 CCC67110.1 - 1.7 7.5 6.1 2.6 6.8 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF342 PF03961.8 CCC67110.1 - 1.8 6.9 7.4 3 6.1 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc7 PF08317.6 CCC67110.1 - 7.4 5.1 15.8 0.034 12.7 4.7 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein Trm112p PF03966.11 CCC67114.1 - 2.2e-19 69.5 0.1 2.7e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein zinc_ribbon_5 PF13719.1 CCC67114.1 - 0.078 12.5 0.0 0.23 11.0 0.0 1.9 1 0 0 1 1 1 0 zinc-ribbon domain Pkinase PF00069.20 CCC67115.1 - 4.3e-74 248.9 0.0 6.6e-74 248.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67115.1 - 1.5e-31 109.4 0.0 1.4e-30 106.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC67115.1 - 3e-08 32.9 0.5 2.4e-05 23.4 0.0 2.8 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 CCC67115.1 - 0.048 12.7 0.0 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC67115.1 - 0.12 12.1 0.0 9.3 5.9 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family CDC50 PF03381.10 CCC67116.1 - 1.4e-96 322.9 0.6 1.7e-96 322.6 0.4 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Mso1_Sec1_bdg PF14475.1 CCC67117.1 - 5.5e-19 67.2 0.0 1.1e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Sec1-binding region of Mso1 KAT11 PF08214.6 CCC67118.1 - 4.2e-92 308.8 0.0 5.1e-92 308.6 0.0 1.0 1 0 0 1 1 1 1 Histone acetylation protein Ribosomal_S6 PF01250.12 CCC67119.1 - 2.5e-06 27.2 0.1 6.1e-06 25.9 0.1 1.7 1 1 0 1 1 1 1 Ribosomal protein S6 RTP801_C PF07809.6 CCC67119.1 - 0.0076 15.9 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 RTP801 C-terminal region DUF3548 PF12068.3 CCC67119.1 - 0.077 12.2 0.1 0.095 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) PAP2 PF01569.16 CCC67120.1 - 3.4e-11 42.9 9.0 3.4e-11 42.9 6.3 2.4 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CCC67120.1 - 2e-05 24.2 7.0 2e-05 24.2 4.8 2.3 2 0 0 2 2 2 1 PAP2 superfamily TFIIS_M PF07500.9 CCC67121.1 - 3.5e-16 59.2 1.4 3.5e-16 59.2 1.0 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 CCC67121.1 - 2.1e-10 40.1 5.2 4.2e-10 39.1 3.6 1.5 1 0 0 1 1 1 1 PHD-finger SPOC PF07744.8 CCC67121.1 - 0.00026 21.4 0.0 0.0007 20.0 0.0 1.7 1 0 0 1 1 1 1 SPOC domain zf-CW PF07496.10 CCC67121.1 - 0.012 15.2 0.3 0.029 14.0 0.2 1.6 1 0 0 1 1 1 0 CW-type Zinc Finger RAG2_PHD PF13341.1 CCC67121.1 - 0.013 15.4 0.4 0.033 14.1 0.2 1.6 1 0 0 1 1 1 0 RAG2 PHD domain Mem_trans PF03547.13 CCC67121.1 - 0.33 9.1 0.6 0.61 8.3 0.4 1.3 1 0 0 1 1 1 0 Membrane transport protein C1_1 PF00130.17 CCC67121.1 - 1.2 8.9 3.8 1.4 8.6 0.5 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_L14e PF01929.12 CCC67122.1 - 1.6e-31 108.4 1.5 2.3e-31 107.9 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CCC67122.1 - 0.00086 18.9 0.5 0.00086 18.9 0.3 1.9 2 0 0 2 2 2 1 KOW motif SNARE PF05739.14 CCC67123.1 - 0.0055 16.3 2.3 0.0068 16.0 1.6 1.1 1 0 0 1 1 1 1 SNARE domain Corona_S2 PF01601.11 CCC67123.1 - 0.015 13.4 1.7 0.016 13.3 1.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Use1 PF09753.4 CCC67123.1 - 0.022 14.1 0.4 0.023 14.1 0.3 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Synaptobrevin PF00957.16 CCC67123.1 - 0.05 13.2 3.0 0.11 12.0 2.1 1.7 1 1 0 1 1 1 0 Synaptobrevin MscS_porin PF12795.2 CCC67123.1 - 0.14 11.4 3.5 0.16 11.2 2.5 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain DUF1664 PF07889.7 CCC67123.1 - 0.16 11.7 0.6 0.24 11.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) F-actin_cap_A PF01267.12 CCC67124.1 - 1.2e-72 244.2 2.4 1.3e-72 244.0 1.7 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Poly_export PF02563.11 CCC67124.1 - 0.11 12.2 0.6 1.7 8.4 0.1 2.4 1 1 1 2 2 2 0 Polysaccharide biosynthesis/export protein Saccharop_dh PF03435.13 CCC67125.1 - 3.2e-129 431.2 0.0 4.1e-129 430.9 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 CCC67125.1 - 1.2e-06 28.7 0.1 2e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 CCC67125.1 - 0.00018 21.6 0.2 0.00029 20.8 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding GFO_IDH_MocA PF01408.17 CCC67125.1 - 0.006 17.0 0.2 0.014 15.9 0.2 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 CCC67125.1 - 0.0086 16.3 0.2 0.02 15.1 0.1 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 CCC67125.1 - 0.054 13.9 0.2 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CCC67125.1 - 0.065 11.9 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 CCC67125.1 - 0.13 11.4 0.2 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family NTF2 PF02136.15 CCC67126.1 - 7.7e-15 55.3 0.2 1.4e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain YqzE PF14038.1 CCC67126.1 - 0.02 14.6 0.7 0.02 14.6 0.5 3.0 3 0 0 3 3 3 0 YqzE-like protein LMBR1 PF04791.11 CCC67126.1 - 1.9 7.0 13.1 0.85 8.1 7.4 1.6 1 1 1 2 2 2 0 LMBR1-like membrane protein CAF1 PF04857.15 CCC67127.1 - 1.2e-53 182.0 0.1 1.2e-53 182.0 0.1 1.8 2 0 0 2 2 2 1 CAF1 family ribonuclease DUF2732 PF10809.3 CCC67127.1 - 0.051 13.1 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2732) CWC25 PF12542.3 CCC67127.1 - 3.1 8.2 11.4 6.2 7.3 7.9 1.5 1 0 0 1 1 1 0 Pre-mRNA splicing factor NGP1NT PF08153.7 CCC67128.1 - 1.9e-50 170.1 0.4 3.4e-50 169.3 0.3 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 CCC67128.1 - 7.3e-20 71.0 0.0 4.8e-15 55.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCC67128.1 - 3e-05 23.3 0.0 0.00016 21.0 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCC67128.1 - 0.00015 21.5 0.3 0.34 10.7 0.0 3.5 2 1 1 3 3 3 1 Dynamin family Arf PF00025.16 CCC67128.1 - 0.00078 18.7 0.1 0.13 11.4 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCC67128.1 - 0.0012 18.3 0.7 0.33 10.3 0.1 3.6 2 2 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CCC67128.1 - 0.0012 18.0 0.0 0.0032 16.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SusD-like_3 PF14322.1 CCC67128.1 - 0.035 14.1 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Starch-binding associating with outer membrane RRM_1 PF00076.17 CCC67129.1 - 0.00022 20.7 0.0 0.022 14.3 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC67129.1 - 0.034 14.1 0.0 0.11 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC67129.1 - 0.096 12.5 0.1 2.5 8.0 0.1 2.6 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cas_Cas4 PF01930.12 CCC67129.1 - 6.1 6.7 10.9 12 5.8 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF83 MFS_1 PF07690.11 CCC67130.1 - 8.6e-35 120.0 47.8 2e-33 115.5 33.1 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Aminotran_1_2 PF00155.16 CCC67131.1 - 1.8e-84 283.7 0.0 2.1e-84 283.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Peptidase_M18 PF02127.10 CCC67132.1 - 5.4e-142 473.3 0.0 7.2e-142 472.8 0.0 1.1 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) SIS PF01380.17 CCC67133.1 - 6e-64 213.5 0.1 4.5e-33 113.6 0.1 2.2 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 CCC67133.1 - 8e-29 100.4 0.0 6.2e-21 74.5 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCC67133.1 - 4.9e-17 62.1 0.0 1.1e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 CCC67133.1 - 1.1e-10 41.3 0.0 2.4e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CCC67133.1 - 3.5e-08 32.4 0.1 6.2e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II COMPASS-Shg1 PF05205.7 CCC67133.1 - 0.065 13.5 0.1 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 COMPASS (Complex proteins associated with Set1p) component shg1 SIS_2 PF13580.1 CCC67133.1 - 0.094 12.4 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 SIS domain Pkinase PF00069.20 CCC67135.1 - 1.5e-72 243.9 0.0 4.8e-72 242.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67135.1 - 6.1e-35 120.5 0.0 3.5e-33 114.7 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CCC67135.1 - 0.006 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC67135.1 - 0.0078 15.9 0.0 0.019 14.6 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Utp11 PF03998.8 CCC67136.1 - 1.2e-72 244.6 30.0 1.4e-72 244.4 20.8 1.0 1 0 0 1 1 1 1 Utp11 protein RVT_2 PF07727.9 CCC67138.1 - 1.7e-13 50.1 0.2 2.7e-13 49.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Cys_Met_Meta_PP PF01053.15 CCC67139.1 - 7.4e-146 485.3 0.0 8.9e-146 485.1 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCC67139.1 - 9.1e-13 47.9 0.0 3.3e-12 46.1 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 CCC67139.1 - 6.3e-09 35.2 0.0 9.9e-09 34.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 CCC67139.1 - 4e-08 32.4 0.1 5.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCC67139.1 - 2.3e-07 30.2 0.0 5.7e-07 28.9 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Met_gamma_lyase PF06838.6 CCC67139.1 - 0.016 13.5 0.1 0.037 12.3 0.0 1.3 1 1 0 1 1 1 0 Methionine gamma-lyase GDC-P PF02347.11 CCC67139.1 - 0.094 11.3 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein RNase_PH PF01138.16 CCC67140.1 - 1.3e-16 61.0 0.4 3e-16 59.9 0.1 1.7 1 1 1 2 2 2 1 3' exoribonuclease family, domain 1 RRM_1 PF00076.17 CCC67141.1 - 5.7e-20 70.7 0.0 1e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC67141.1 - 3.1e-14 52.6 0.0 5.6e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC67141.1 - 3.4e-10 39.6 0.0 5.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 CCC67141.1 - 7.1e-06 26.0 0.3 7.1e-06 26.0 0.2 1.6 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 CCC67141.1 - 0.0001 21.5 0.3 0.00019 20.6 0.2 1.4 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal BSD PF03909.12 CCC67141.1 - 0.21 11.3 3.6 1.2 8.8 0.4 2.4 2 0 0 2 2 2 0 BSD domain TFIIS_M PF07500.9 CCC67142.1 - 4.4e-29 100.8 2.7 4.4e-29 100.8 1.9 2.1 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 CCC67142.1 - 1.9e-17 62.6 6.3 3.1e-17 61.8 4.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 CCC67142.1 - 2.1e-14 52.7 1.8 6.3e-14 51.2 1.3 1.9 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Gly_radical PF01228.16 CCC67142.1 - 0.17 12.2 3.1 0.12 12.6 0.3 2.2 2 1 0 2 2 2 0 Glycine radical ResB PF05140.9 CCC67142.1 - 0.19 10.2 1.3 0.25 9.8 0.9 1.2 1 0 0 1 1 1 0 ResB-like family Ribosomal_S27 PF01599.14 CCC67142.1 - 0.25 11.2 2.5 2 8.2 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S27a Zn_Tnp_IS1595 PF12760.2 CCC67142.1 - 1.7 8.5 5.5 6 6.7 3.9 1.8 1 1 0 1 1 1 0 Transposase zinc-ribbon domain RDM PF11002.3 CCC67143.1 - 0.067 12.8 0.3 0.15 11.7 0.2 1.6 1 0 0 1 1 1 0 RFPL defining motif (RDM) TYW3 PF02676.9 CCC67144.1 - 3.4e-67 225.5 0.0 4.3e-67 225.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase TYW3 MIF4G PF02854.14 CCC67145.1 - 2.5e-48 164.2 0.1 4e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 CCC67145.1 - 2.5e-24 84.9 1.8 2.5e-24 84.9 1.3 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 4G1 AAA PF00004.24 CCC67146.1 - 4.4e-43 146.6 0.0 8.5e-43 145.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCC67146.1 - 1e-06 28.7 0.0 2.2e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCC67146.1 - 1.2e-06 28.3 0.0 8.5e-06 25.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCC67146.1 - 5.2e-06 26.6 0.0 0.00033 20.7 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC67146.1 - 2.3e-05 24.4 0.0 0.00012 22.1 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CCC67146.1 - 4.5e-05 24.2 0.3 0.00014 22.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCC67146.1 - 0.00013 21.5 0.1 0.00031 20.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 CCC67146.1 - 0.00015 20.9 0.0 0.00027 20.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 CCC67146.1 - 0.00024 20.5 0.0 0.00044 19.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCC67146.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCC67146.1 - 0.0017 18.2 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCC67146.1 - 0.0018 18.2 0.0 0.0036 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2072 PF09845.4 CCC67146.1 - 0.0029 17.5 0.3 0.0066 16.3 0.2 1.6 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) Zeta_toxin PF06414.7 CCC67146.1 - 0.003 16.6 0.0 0.0068 15.5 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 CCC67146.1 - 0.0052 16.3 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CCC67146.1 - 0.0079 16.5 1.5 0.032 14.5 0.0 2.7 3 1 0 3 3 3 1 AAA domain TIP49 PF06068.8 CCC67146.1 - 0.0095 14.6 0.0 0.022 13.4 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 CCC67146.1 - 0.01 15.0 0.2 0.025 13.7 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CCC67146.1 - 0.014 14.6 0.0 0.046 12.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activat PF00158.21 CCC67146.1 - 0.024 14.0 0.0 0.15 11.5 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_25 PF13481.1 CCC67146.1 - 0.028 13.8 0.1 0.094 12.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 CCC67146.1 - 0.032 13.8 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCC67146.1 - 0.032 14.3 0.0 0.076 13.1 0.0 1.7 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.7 CCC67146.1 - 0.074 12.7 0.0 0.36 10.4 0.0 2.0 1 1 1 2 2 2 0 NACHT domain DUF815 PF05673.8 CCC67146.1 - 0.079 11.8 0.1 0.16 10.8 0.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 CCC67146.1 - 0.087 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 RRM_1 PF00076.17 CCC67147.1 - 7.3e-46 153.6 0.0 8.6e-22 76.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC67147.1 - 1.8e-28 98.3 0.0 3.9e-14 52.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC67147.1 - 7.9e-21 73.6 0.0 6.2e-11 41.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCC67147.1 - 0.015 15.0 0.0 1.4 8.7 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CCC67147.1 - 0.019 14.6 0.0 0.38 10.5 0.0 3.0 2 1 0 2 2 2 0 Limkain b1 DUF966 PF06136.8 CCC67147.1 - 0.079 12.3 38.2 0.11 11.8 26.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.4 CCC67147.1 - 0.11 10.7 38.3 0.17 10.1 26.5 1.3 1 0 0 1 1 1 0 Transmembrane protein CDC27 PF09507.5 CCC67147.1 - 1.7 7.8 61.0 2.4 7.3 42.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 MIP-T3 PF10243.4 CCC67147.1 - 7.2 4.9 60.4 9.6 4.5 41.9 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Arrestin_N PF00339.24 CCC67148.1 - 1.6e-20 73.4 0.4 5.5e-20 71.7 0.2 2.0 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CCC67148.1 - 9.9e-08 32.1 5.1 2.7e-05 24.2 0.1 3.0 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain NikR_C PF08753.6 CCC67148.1 - 0.1 12.4 0.3 0.23 11.3 0.2 1.5 1 0 0 1 1 1 0 NikR C terminal nickel binding domain DUF4662 PF15578.1 CCC67149.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4662) Aconitase PF00330.15 CCC67150.1 - 2.5e-181 603.2 0.0 5.8e-181 602.0 0.0 1.6 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCC67150.1 - 4.7e-48 162.6 0.0 1.1e-47 161.4 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain PI3_PI4_kinase PF00454.22 CCC67151.1 - 5.9e-45 153.5 0.0 2e-44 151.8 0.0 2.0 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 CCC67151.1 - 3.1e-26 91.6 0.0 9.4e-26 90.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) UQ_con PF00179.21 CCC67152.1 - 9.3e-36 122.3 0.0 1.1e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCC67152.1 - 0.04 13.6 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.8 CCC67152.1 - 0.091 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 UEV domain Polysacc_deac_1 PF01522.16 CCC67153.1 - 2.5e-27 94.9 0.1 4.3e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 CCC67153.1 - 1.5e-05 24.1 0.0 2e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 GRIP PF01465.15 CCC67154.1 - 1.2e-14 53.5 0.8 3.4e-14 52.0 0.6 1.9 1 0 0 1 1 1 1 GRIP domain RasGEF PF00617.14 CCC67155.1 - 7.5e-60 201.8 1.4 2.1e-59 200.4 0.0 2.5 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 CCC67155.1 - 2.2e-17 63.0 0.2 2.2e-17 63.0 0.1 3.4 4 0 0 4 4 4 1 RasGEF N-terminal motif SH3_9 PF14604.1 CCC67155.1 - 7.4e-12 44.6 0.1 1.6e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCC67155.1 - 5.3e-11 41.7 0.1 1.1e-10 40.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCC67155.1 - 9.2e-06 25.0 0.0 6.1e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain tRNA-synt_2 PF00152.15 CCC67156.1 - 1.7e-80 270.2 0.2 1.7e-80 270.2 0.1 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCC67156.1 - 3.5e-07 29.9 0.6 6.9e-07 29.0 0.4 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCC67156.1 - 0.0081 15.3 0.8 1.4 8.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF4355 PF14265.1 CCC67156.1 - 2.6 7.9 17.9 6 6.8 12.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) CHCH PF06747.8 CCC67157.1 - 0.00043 20.1 3.2 0.001 18.9 2.2 1.6 1 1 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 CCC67157.1 - 0.0057 16.6 4.0 0.21 11.6 2.9 2.0 1 1 1 2 2 2 2 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 CCC67157.1 - 0.028 14.4 0.3 0.036 14.0 0.2 1.1 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 CCC67157.1 - 0.16 11.7 2.1 0.22 11.3 1.5 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pkinase PF00069.20 CCC67158.1 - 9.7e-49 165.8 0.0 7e-48 163.0 0.0 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67158.1 - 4.5e-17 61.9 0.0 1.1e-16 60.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC67158.1 - 0.055 12.4 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 CCC67158.1 - 0.062 12.3 0.0 0.16 10.9 0.0 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GIT_SHD PF08518.6 CCC67159.1 - 1.6e-25 88.1 7.6 5.1e-14 51.3 0.7 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF3021 PF11457.3 CCC67159.1 - 0.2 11.5 0.9 0.48 10.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) bZIP_1 PF00170.16 CCC67159.1 - 5.3 7.0 17.3 0.61 10.0 2.9 3.5 3 0 0 3 3 3 0 bZIP transcription factor SHNi-TPR PF10516.4 CCC67160.1 - 0.017 14.3 0.3 0.032 13.4 0.2 1.5 1 0 0 1 1 1 0 SHNi-TPR TPR_16 PF13432.1 CCC67160.1 - 0.06 14.0 0.9 0.06 14.0 0.6 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCC67160.1 - 0.064 13.1 3.9 0.11 12.3 0.4 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF2146 PF10220.4 CCC67160.1 - 0.39 8.6 8.1 0.62 7.9 5.6 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DUF2201_N PF13203.1 CCC67160.1 - 1.7 7.7 4.5 2.7 7.0 3.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Daxx PF03344.10 CCC67160.1 - 3.1 6.1 17.7 5.4 5.3 12.2 1.4 1 0 0 1 1 1 0 Daxx Family BUD22 PF09073.5 CCC67160.1 - 6.6 5.6 22.6 0.89 8.5 12.6 1.7 2 0 0 2 2 2 0 BUD22 UPF0121 PF03661.8 CCC67161.1 - 1.9e-09 37.1 8.8 2.6e-09 36.6 6.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) rve PF00665.21 CCC67162.1 - 4.7e-10 39.6 0.0 9.7e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain DUF2183 PF09949.4 CCC67162.1 - 0.0022 17.8 0.1 0.0097 15.8 0.0 2.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF2264 PF10022.4 CCC67163.1 - 0.021 13.4 0.1 0.031 12.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2264) Fzo_mitofusin PF04799.8 CCC67163.1 - 0.18 11.1 3.4 0.15 11.4 0.5 2.2 2 0 0 2 2 2 0 fzo-like conserved region Ribosomal_S3Ae PF01015.13 CCC67164.1 - 5.4e-81 270.5 7.4 6.4e-81 270.3 5.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Inhibitor_I9 PF05922.11 CCC67164.1 - 0.042 14.4 0.1 0.095 13.2 0.0 1.8 1 0 0 1 1 1 0 Peptidase inhibitor I9 Abhydro_lipase PF04083.11 CCC67164.1 - 0.043 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ras PF00071.17 CCC67165.1 - 9.7e-31 106.3 0.1 1.2e-30 106.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC67165.1 - 1.2e-17 64.5 0.1 2.6e-17 63.4 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 CCC67165.1 - 1.6e-05 24.1 0.2 2e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCC67165.1 - 0.00011 21.6 0.2 0.00086 18.7 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 CCC67165.1 - 0.0002 20.6 0.1 0.00026 20.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCC67165.1 - 0.012 15.5 0.1 0.018 14.9 0.1 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 CCC67165.1 - 0.035 13.6 0.1 0.26 10.8 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CCC67165.1 - 0.1 12.0 0.4 0.67 9.4 0.3 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 CCC67166.1 - 3.3e-19 69.3 0.1 1.1e-18 67.6 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BAH PF01426.13 CCC67166.1 - 4.8e-10 39.2 0.3 1.4e-09 37.7 0.2 1.9 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 CCC67166.1 - 2.7e-06 27.5 0.0 9.7e-06 25.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC67166.1 - 1.2e-05 25.3 0.0 9.5e-05 22.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.7 CCC67166.1 - 0.0018 17.9 0.0 0.0053 16.4 0.0 1.8 1 1 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 CCC67166.1 - 0.032 14.3 0.0 0.17 12.0 0.0 2.3 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 CCC67166.1 - 0.045 13.5 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 CCC67166.1 - 0.051 14.3 0.5 0.37 11.5 0.0 2.8 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.13 CCC67166.1 - 0.1 12.0 0.8 0.36 10.2 0.0 2.2 3 0 0 3 3 3 0 FtsK/SpoIIIE family Claudin_2 PF13903.1 CCC67167.1 - 0.0044 16.7 0.5 0.0044 16.7 0.3 1.5 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Fig1 PF12351.3 CCC67167.1 - 0.42 10.4 9.0 2.9 7.7 0.0 3.1 3 0 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 COPIIcoated_ERV PF07970.7 CCC67168.1 - 4.3e-30 104.9 0.0 6.2e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCC67168.1 - 3.2e-19 68.6 0.0 5.6e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) IBR PF01485.16 CCC67169.1 - 8.8e-16 57.5 45.0 5.6e-09 35.7 2.4 4.2 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 CCC67169.1 - 5.7e-05 22.8 7.2 5.7e-05 22.8 5.0 4.6 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCC67169.1 - 0.00013 21.8 9.6 0.00013 21.8 6.6 4.7 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SSrecog PF03531.9 CCC67170.1 - 6.8e-70 234.8 4.0 6.3e-69 231.7 1.9 2.7 2 1 0 2 2 2 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 CCC67170.1 - 1.1e-30 105.4 0.2 9.2e-28 96.0 0.0 3.2 3 0 0 3 3 3 2 Histone chaperone Rttp106-like Dak1 PF02733.12 CCC67171.1 - 2.7e-140 466.5 2.6 3.5e-140 466.1 1.8 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 CCC67171.1 - 1.6e-44 151.6 0.8 1.6e-44 151.6 0.5 1.6 2 0 0 2 2 2 1 DAK2 domain UPF0184 PF03670.8 CCC67171.1 - 0.11 12.6 0.1 0.72 10.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Dor1 PF04124.7 CCC67172.1 - 8.8e-43 146.0 10.5 8.8e-43 146.0 7.3 1.8 2 1 0 2 2 2 1 Dor1-like family Sec5 PF15469.1 CCC67172.1 - 1.7e-05 24.6 7.2 1.8e-05 24.5 2.2 2.5 1 1 1 2 2 2 1 Exocyst complex component Sec5 Helicase_C_3 PF13625.1 CCC67172.1 - 0.015 15.0 0.1 0.066 12.9 0.0 2.0 2 0 0 2 2 2 0 Helicase conserved C-terminal domain C2 PF00168.25 CCC67173.1 - 1.3e-51 172.3 4.8 1.6e-18 66.2 0.0 5.3 5 0 0 5 5 5 4 C2 domain CBP4 PF07960.6 CCC67173.1 - 0.011 15.3 3.0 0.027 14.0 2.1 1.6 1 0 0 1 1 1 0 CBP4 DUF4131 PF13567.1 CCC67173.1 - 0.099 12.0 0.3 0.18 11.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Ribosomal_L6e PF01159.14 CCC67174.1 - 3e-39 133.5 2.1 4.4e-39 133.0 1.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e SLEI_Leptospira PF07620.6 CCC67174.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 SLEI FKBP_C PF00254.23 CCC67175.1 - 9.5e-29 99.2 0.2 5.1e-28 96.9 0.0 2.3 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Vfa1 PF08432.5 CCC67175.1 - 0.045 13.7 36.0 0.31 11.0 10.8 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Rtf2 PF04641.7 CCC67175.1 - 0.3 10.2 30.4 0.026 13.7 3.6 2.1 2 0 0 2 2 2 0 Rtf2 RING-finger SDA1 PF05285.7 CCC67175.1 - 0.38 9.9 57.4 0.14 11.3 13.2 2.1 2 0 0 2 2 2 0 SDA1 DUF572 PF04502.8 CCC67175.1 - 0.38 9.9 30.7 0.4 9.8 8.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) GAGA_bind PF06217.7 CCC67175.1 - 1 9.2 19.2 2.6 7.9 1.8 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family DUF1764 PF08576.5 CCC67175.1 - 2.1 9.2 29.6 5 7.9 9.0 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) RNase_H2-Ydr279 PF09468.5 CCC67175.1 - 3.8 6.6 24.1 0.91 8.6 6.4 2.2 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Daxx PF03344.10 CCC67175.1 - 4 5.8 51.2 1.2 7.5 13.0 2.0 2 0 0 2 2 2 0 Daxx Family DUF2956 PF11169.3 CCC67175.1 - 4.6 7.2 22.6 0.88 9.5 2.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) HMG-CoA_red PF00368.13 CCC67176.1 - 5.2e-157 522.2 0.1 6.8e-157 521.9 0.1 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 CCC67176.1 - 4.3e-42 143.3 2.1 4.3e-42 143.3 1.5 1.8 2 0 0 2 2 2 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 CCC67176.1 - 5.7e-06 25.8 7.0 5.7e-06 25.8 4.8 2.0 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation DUF3115 PF11312.3 CCC67176.1 - 0.085 11.6 0.2 0.19 10.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Zn_clus PF00172.13 CCC67177.1 - 0.0058 16.5 9.7 0.014 15.2 6.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4467 PF14729.1 CCC67177.1 - 0.032 14.5 0.0 0.11 12.8 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function with cystatin-like fold (DUF4467) Sybindin PF04099.7 CCC67178.1 - 3.5e-20 72.1 0.6 4.6e-20 71.7 0.4 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 CCC67178.1 - 0.00026 20.8 0.3 0.00031 20.6 0.2 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region EAP30 PF04157.11 CCC67178.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family ENTH PF01417.15 CCC67179.1 - 6.3e-44 148.8 0.1 1.3e-43 147.8 0.1 1.5 1 0 0 1 1 1 1 ENTH domain VHS PF00790.14 CCC67179.1 - 6.6e-05 22.5 0.1 0.00011 21.7 0.0 1.3 1 0 0 1 1 1 1 VHS domain ANTH PF07651.11 CCC67179.1 - 0.0033 16.1 0.0 0.0051 15.5 0.0 1.3 1 0 0 1 1 1 1 ANTH domain DUF3991 PF13154.1 CCC67179.1 - 0.03 14.5 0.1 1.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3991) GET2 PF08690.5 CCC67179.1 - 3.9 6.6 8.7 8.2 5.5 6.1 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4611 PF15387.1 CCC67179.1 - 8.7 6.5 11.4 4.2 7.5 0.2 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Pro_isomerase PF00160.16 CCC67180.1 - 6.9e-49 166.0 0.4 8e-49 165.8 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cupin_5 PF06172.6 CCC67181.1 - 1.6e-37 128.4 0.0 2e-37 128.2 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Dus PF01207.12 CCC67182.1 - 2.6e-78 262.9 0.0 3.4e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-H2C2_2 PF13465.1 CCC67183.1 - 9.3e-07 28.8 10.8 2.3e-05 24.4 3.5 2.7 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 CCC67183.1 - 2.1e-06 27.7 14.6 0.00024 21.2 2.0 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC67183.1 - 0.01 16.0 14.6 0.067 13.5 2.0 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger CstA PF02554.9 CCC67183.1 - 0.094 11.3 0.1 0.16 10.5 0.1 1.3 1 0 0 1 1 1 0 Carbon starvation protein CstA ATP-synt_J PF04911.7 CCC67184.1 - 7.5e-28 95.7 1.1 8.6e-28 95.5 0.8 1.1 1 0 0 1 1 1 1 ATP synthase j chain Cys_Met_Meta_PP PF01053.15 CCC67185.1 - 1.7e-25 89.1 0.0 1e-14 53.6 0.0 2.3 3 0 0 3 3 3 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 CCC67185.1 - 0.011 14.6 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Ctf8 PF09696.5 CCC67186.1 - 2.6e-23 82.1 0.3 3.8e-23 81.5 0.2 1.3 1 0 0 1 1 1 1 Ctf8 DUF2296 PF10058.4 CCC67187.1 - 6.6e-15 54.6 0.2 1.1e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) 4HB_MCP_1 PF12729.2 CCC67187.1 - 0.00085 18.7 7.3 0.18 11.1 3.8 2.3 2 0 0 2 2 2 2 Four helix bundle sensory module for signal transduction DSHCT PF08148.7 CCC67187.1 - 0.035 13.3 0.1 0.17 11.1 0.0 1.9 2 0 0 2 2 2 0 DSHCT (NUC185) domain DASH_Duo1 PF08651.5 CCC67187.1 - 0.046 13.3 5.6 0.89 9.1 0.1 2.5 2 0 0 2 2 2 0 DASH complex subunit Duo1 DUF2721 PF11026.3 CCC67187.1 - 0.05 13.2 0.9 0.082 12.5 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) U3_assoc_6 PF08640.6 CCC67187.1 - 0.054 13.2 0.3 0.054 13.2 0.2 2.2 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 6 End3 PF12761.2 CCC67187.1 - 0.062 12.9 0.5 0.062 12.9 0.3 2.4 2 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 A2L_zn_ribbon PF08792.5 CCC67187.1 - 0.29 10.6 3.5 0.56 9.7 0.1 2.4 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF4446 PF14584.1 CCC67187.1 - 0.44 10.3 4.6 2.5 7.9 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF4446) AAA_13 PF13166.1 CCC67187.1 - 0.5 8.7 12.3 1.7 6.9 0.0 2.8 3 0 0 3 3 3 0 AAA domain zf-ribbon_3 PF13248.1 CCC67187.1 - 1.3 8.2 3.7 6.5 6.1 0.3 2.2 2 0 0 2 2 2 0 zinc-ribbon domain IncA PF04156.9 CCC67187.1 - 1.4 8.4 9.2 1.6 8.2 0.3 2.3 2 0 0 2 2 2 0 IncA protein OmpH PF03938.9 CCC67187.1 - 2.8 7.8 11.1 1.4 8.8 3.8 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ATG16 PF08614.6 CCC67187.1 - 2.9 7.6 16.1 7.9 6.2 0.3 2.2 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Prefoldin PF02996.12 CCC67187.1 - 9.6 5.8 13.1 0.28 10.8 0.6 3.0 2 1 1 3 3 3 0 Prefoldin subunit NAC PF01849.13 CCC67188.1 - 2.4e-18 65.3 0.2 5.3e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 CCC67188.1 - 0.0004 20.1 0.2 0.0015 18.3 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 CCC67188.1 - 0.047 13.2 0.0 0.092 12.2 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain ABC_tran PF00005.22 CCC67189.1 - 2.1e-46 157.6 0.0 3e-23 82.6 0.0 4.3 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCC67189.1 - 3.7e-19 69.7 3.6 3.5e-05 23.8 0.0 4.4 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 CCC67189.1 - 3.9e-16 58.9 0.3 2.1e-07 30.3 0.0 3.8 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CCC67189.1 - 9.7e-10 38.6 0.3 4.9e-05 23.4 0.0 4.4 5 1 0 5 5 4 2 AAA domain AAA_29 PF13555.1 CCC67189.1 - 2.3e-09 36.6 0.0 0.0025 17.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.1 CCC67189.1 - 1.4e-08 34.9 0.0 0.0005 20.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 CCC67189.1 - 1.8e-08 34.3 0.0 1.2e-05 25.2 0.0 3.0 2 0 0 2 2 2 1 Dynamin family DUF258 PF03193.11 CCC67189.1 - 2.5e-08 33.2 0.1 0.00075 18.7 0.0 2.9 2 1 1 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCC67189.1 - 5.5e-08 33.6 0.0 0.013 16.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CCC67189.1 - 2.5e-07 30.6 0.1 0.0061 16.5 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 CCC67189.1 - 5.3e-07 30.1 10.7 0.00066 20.0 0.0 3.7 5 0 0 5 5 2 2 AAA domain ArgK PF03308.11 CCC67189.1 - 2e-06 26.7 0.0 0.031 13.0 0.0 2.5 2 0 0 2 2 2 2 ArgK protein HEAT_2 PF13646.1 CCC67189.1 - 2.2e-06 27.8 0.0 0.0034 17.6 0.0 3.8 1 1 3 4 4 4 1 HEAT repeats RNA_helicase PF00910.17 CCC67189.1 - 2.7e-06 27.4 0.0 0.13 12.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA PF00004.24 CCC67189.1 - 2.7e-06 27.5 0.1 0.068 13.3 0.0 4.4 5 0 0 5 5 3 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 CCC67189.1 - 3.7e-06 27.4 0.0 0.089 13.2 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 CCC67189.1 - 4.6e-06 26.4 0.0 0.012 15.5 0.0 3.1 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 CCC67189.1 - 4.8e-06 26.9 0.1 0.24 11.7 0.0 3.5 4 0 0 4 4 2 2 AAA domain AAA_14 PF13173.1 CCC67189.1 - 8.5e-06 25.6 0.0 0.056 13.3 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 CCC67189.1 - 8.5e-06 25.7 0.0 0.097 12.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 CCC67189.1 - 1.1e-05 25.0 0.0 0.17 11.2 0.0 2.9 3 0 0 3 3 2 2 AAA-like domain MobB PF03205.9 CCC67189.1 - 2.6e-05 23.9 0.0 0.38 10.4 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CCC67189.1 - 5.7e-05 22.9 0.1 0.5 10.0 0.0 3.2 3 0 0 3 3 3 2 Archaeal ATPase ParcG PF10274.4 CCC67189.1 - 6.7e-05 22.8 1.5 0.51 10.2 0.0 3.3 2 1 1 3 3 3 2 Parkin co-regulated protein AAA_13 PF13166.1 CCC67189.1 - 9.3e-05 21.0 1.2 1.2 7.5 0.0 3.9 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 CCC67189.1 - 9.9e-05 22.3 0.6 0.15 12.0 0.1 3.6 3 1 0 3 3 2 1 AAA ATPase domain cobW PF02492.14 CCC67189.1 - 0.00012 21.5 0.2 1.7 8.0 0.0 4.1 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 CCC67189.1 - 0.00017 21.5 5.1 0.3 10.8 0.0 4.6 6 0 0 6 6 3 1 Domain of unknown function DUF87 MutS_V PF00488.16 CCC67189.1 - 0.00019 20.9 0.0 0.1 11.9 0.0 2.6 2 0 0 2 2 2 1 MutS domain V NACHT PF05729.7 CCC67189.1 - 0.00021 20.9 0.0 0.14 11.7 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Adaptin_N PF01602.15 CCC67189.1 - 0.00027 19.4 6.9 0.0038 15.6 3.0 2.2 1 1 0 2 2 2 1 Adaptin N terminal region PduV-EutP PF10662.4 CCC67189.1 - 0.00043 19.7 0.1 0.36 10.3 0.0 3.2 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation CLASP_N PF12348.3 CCC67189.1 - 0.0022 17.3 2.2 0.5 9.6 0.2 2.9 2 1 1 3 3 2 1 CLASP N terminal AAA_30 PF13604.1 CCC67189.1 - 0.0028 17.2 0.0 3.8 7.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 CCC67189.1 - 0.0056 15.7 0.0 1.2 8.2 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin UME PF08064.8 CCC67189.1 - 0.0076 16.1 1.7 0.11 12.4 1.3 2.7 2 1 0 3 3 2 1 UME (NUC010) domain HEAT_EZ PF13513.1 CCC67189.1 - 0.013 16.0 0.5 2.4 8.7 0.0 4.1 3 1 1 4 4 3 0 HEAT-like repeat Septin PF00735.13 CCC67189.1 - 0.013 14.5 0.9 1.5 7.7 0.0 2.6 3 0 0 3 3 2 0 Septin HEAT PF02985.17 CCC67189.1 - 0.02 14.9 0.7 20 5.6 0.0 4.5 5 0 0 5 5 4 0 HEAT repeat GTP_EFTU PF00009.22 CCC67189.1 - 0.02 14.3 0.0 8 5.8 0.0 3.0 3 0 0 3 3 2 0 Elongation factor Tu GTP binding domain Mg_chelatase PF01078.16 CCC67189.1 - 0.026 13.7 0.6 2 7.5 0.0 3.3 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Vac14_Fab1_bd PF12755.2 CCC67189.1 - 0.029 14.7 0.1 4.6 7.7 0.0 3.1 2 1 1 3 3 2 0 Vacuolar 14 Fab1-binding region AAA_25 PF13481.1 CCC67189.1 - 0.035 13.4 0.0 9.8 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CCC67189.1 - 0.043 13.3 0.0 2.2 7.7 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_19 PF13245.1 CCC67189.1 - 0.045 13.5 0.0 6 6.6 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain IstB_IS21 PF01695.12 CCC67189.1 - 0.05 13.0 0.0 3.2 7.1 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein ATP_bind_1 PF03029.12 CCC67189.1 - 0.051 13.1 0.1 8.2 5.8 0.0 2.9 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF3385 PF11865.3 CCC67189.1 - 0.12 12.3 3.5 12 5.8 0.0 3.7 2 1 2 4 4 3 0 Domain of unknown function (DUF3385) FeoB_N PF02421.13 CCC67189.1 - 0.16 11.2 2.1 1 8.6 0.0 3.0 3 0 0 3 3 3 0 Ferrous iron transport protein B MDM31_MDM32 PF08118.6 CCC67190.1 - 5.6e-258 856.3 7.5 6.6e-258 856.1 5.2 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins RIX1 PF08167.7 CCC67192.1 - 8.6e-42 142.6 1.3 8.6e-42 142.6 0.9 2.4 3 0 0 3 3 3 1 rRNA processing/ribosome biogenesis DUF281 PF03436.8 CCC67192.1 - 0.099 12.7 0.0 0.27 11.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF281) Chalcone PF02431.10 CCC67193.1 - 1.8e-49 167.8 0.2 3.3e-48 163.7 0.0 2.0 2 0 0 2 2 2 1 Chalcone-flavanone isomerase CCSMST1 PF15013.1 CCC67193.1 - 0.075 12.9 0.2 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 CCSMST1 family VWA_2 PF13519.1 CCC67194.1 - 1.7e-08 34.7 0.0 2.4e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 CCC67194.1 - 8.1e-06 25.5 0.3 1.1e-05 25.1 0.2 1.2 1 0 0 1 1 1 1 Ssl1-like HNOBA PF07701.9 CCC67194.1 - 0.02 14.1 1.3 0.073 12.2 0.0 2.0 2 0 0 2 2 2 0 Heme NO binding associated RE_R_Pab1 PF09522.5 CCC67194.1 - 0.022 14.7 0.4 0.034 14.0 0.3 1.2 1 0 0 1 1 1 0 R.Pab1 restriction endonuclease UIM PF02809.15 CCC67194.1 - 0.034 13.7 1.5 0.076 12.6 1.1 1.6 1 0 0 1 1 1 0 Ubiquitin interaction motif Homoserine_dh PF00742.14 CCC67195.1 - 2.8e-54 183.5 0.1 4.1e-54 182.9 0.1 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 CCC67195.1 - 1.8e-22 79.8 0.0 3.2e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF2555 PF10742.4 CCC67195.1 - 0.1 12.2 0.0 0.51 10.0 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2555) DHHA2 PF02833.9 CCC67196.1 - 4.3e-29 101.2 0.5 6.9e-29 100.6 0.3 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 CCC67196.1 - 8e-09 35.2 0.2 1.1e-07 31.5 0.1 2.4 1 1 0 1 1 1 1 DHH family Mgm101p PF06420.7 CCC67197.1 - 1.1e-88 295.0 0.0 1.7e-88 294.3 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Metallophos PF00149.23 CCC67198.1 - 6.5e-07 28.9 10.1 1.5e-06 27.7 7.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_S4e PF00900.15 CCC67199.1 - 5.3e-33 112.5 1.5 3e-32 110.1 0.6 2.1 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CCC67199.1 - 6.9e-20 70.6 4.4 1.4e-19 69.6 3.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CCC67199.1 - 1.4e-07 30.8 0.5 2.6e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 CCC67199.1 - 1.1e-05 24.8 1.5 1.1e-05 24.8 1.0 3.3 4 0 0 4 4 4 1 KOW motif Dimer_Tnp_hAT PF05699.9 CCC67200.1 - 0.0017 17.9 0.1 0.0046 16.5 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SUFU_C PF12470.3 CCC67200.1 - 0.063 12.8 0.5 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain Glyco_hydro_47 PF01532.15 CCC67201.1 - 5.3e-118 394.5 0.9 7e-118 394.1 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Pkinase PF00069.20 CCC67202.1 - 1.9e-68 230.4 0.0 5.2e-68 228.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67202.1 - 6.8e-31 107.2 0.0 1e-30 106.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCC67202.1 - 4.5e-11 43.0 1.7 4.5e-11 43.0 1.2 2.7 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCC67202.1 - 1.9e-09 36.9 0.0 3.9e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 Kinase-like C2 PF00168.25 CCC67202.1 - 3.8e-06 26.6 0.1 0.00011 22.0 0.0 2.9 1 1 0 1 1 1 1 C2 domain YrbL-PhoP_reg PF10707.4 CCC67202.1 - 0.021 14.1 0.1 0.05 12.9 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.18 CCC67202.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HSF_DNA-bind PF00447.12 CCC67203.1 - 7.6e-35 119.2 1.6 2e-34 117.8 1.1 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 CCC67203.1 - 4.3e-27 94.3 0.3 8.7e-27 93.3 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HALZ PF02183.13 CCC67203.1 - 0.0004 20.0 0.5 0.00088 18.9 0.4 1.5 1 0 0 1 1 1 1 Homeobox associated leucine zipper EzrA PF06160.7 CCC67203.1 - 0.034 12.3 0.5 0.071 11.2 0.4 1.4 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA SET PF00856.23 CCC67204.1 - 1.4e-14 54.7 0.1 6.3e-13 49.3 0.1 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 CCC67204.1 - 7.4 6.5 13.0 0.83 9.5 4.5 2.5 2 0 0 2 2 2 0 MYND finger Fungal_trans PF04082.13 CCC67207.1 - 2.8e-05 23.1 4.5 3.4e-05 22.8 2.3 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC67207.1 - 0.00014 21.6 10.7 0.00024 20.9 7.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 CCC67209.1 - 1.1e-15 56.7 4.7 5.6e-06 26.0 0.0 4.9 5 1 0 5 5 5 3 WD domain, G-beta repeat Sulfatase_C PF14707.1 CCC67209.1 - 0.072 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase Imm46 PF15585.1 CCC67210.1 - 0.016 15.2 0.3 0.08 12.9 0.0 2.2 2 1 1 3 3 3 0 Immunity protein 46 Phage_GP20 PF06810.6 CCC67210.1 - 0.06 12.7 11.4 0.028 13.8 2.2 2.5 1 1 0 2 2 2 0 Phage minor structural protein GP20 Retrotrans_gag PF03732.12 CCC67210.1 - 0.11 12.5 1.5 0.69 10.0 0.1 2.6 2 1 0 2 2 2 0 Retrotransposon gag protein TMF_TATA_bd PF12325.3 CCC67210.1 - 0.34 10.6 13.1 0.55 9.9 0.2 4.0 2 1 2 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF3417 PF11897.3 CCC67210.1 - 0.35 10.8 2.4 0.51 10.3 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3417) DUF1664 PF07889.7 CCC67210.1 - 1.6 8.5 6.1 2.3 8.0 0.6 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 CCC67210.1 - 2 8.7 10.4 2.2 8.5 0.6 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein E1-E2_ATPase PF00122.15 CCC67211.1 - 4.5e-63 212.3 2.3 4.5e-63 212.3 1.6 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCC67211.1 - 8.9e-42 142.6 6.5 8.9e-42 142.6 4.5 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCC67211.1 - 5.9e-25 88.9 0.0 2.6e-24 86.8 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCC67211.1 - 7.1e-13 49.1 0.0 3.2e-12 47.0 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCC67211.1 - 8.2e-13 48.1 0.0 2.6e-12 46.5 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 CCC67211.1 - 1.5e-09 37.1 0.0 5.6e-09 35.3 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCC67211.1 - 0.00057 19.5 0.4 0.00057 19.5 0.2 3.3 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 CCC67212.1 - 1.7e-61 207.1 5.7 1.7e-61 207.1 4.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCC67212.1 - 1.4e-23 84.4 0.1 2.5e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCC67212.1 - 4.7e-15 56.2 0.0 1.1e-14 55.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCC67212.1 - 2.8e-11 42.7 0.4 1e-10 40.9 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCC67212.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCC67212.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit SIS_2 PF13580.1 CCC67212.1 - 0.047 13.4 0.0 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 SIS domain MLANA PF14991.1 CCC67212.1 - 7.5 6.5 5.5 2.2 8.3 0.1 2.4 2 0 0 2 2 2 0 Protein melan-A PUF PF00806.14 CCC67213.1 - 5.1e-66 214.6 16.6 4.7e-09 35.2 0.2 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Inositol_P PF00459.20 CCC67214.1 - 1.2e-66 224.7 0.0 1.3e-66 224.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Peptidase_M1 PF01433.15 CCC67215.1 - 4.7e-142 473.6 1.7 6.4e-142 473.2 1.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 CCC67215.1 - 4.9e-84 282.3 0.7 7.4e-83 278.4 0.1 2.4 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CCC67215.1 - 8.1e-21 74.3 0.2 1.7e-20 73.3 0.2 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily MFS_1 PF07690.11 CCC67216.1 - 1.1e-35 123.0 28.7 1.1e-35 123.0 19.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Tmemb_cc2 PF10267.4 CCC67216.1 - 0.56 8.7 5.0 3.2 6.2 0.6 2.2 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein FSH1 PF03959.8 CCC67217.1 - 7.2e-65 218.3 0.0 8e-65 218.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CCC67217.1 - 1.2e-05 25.0 0.0 1.7e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCC67217.1 - 0.00032 20.1 0.4 0.55 9.6 0.2 2.6 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 CCC67217.1 - 0.00053 19.9 0.0 0.12 12.2 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family BAAT_C PF08840.6 CCC67217.1 - 0.0013 18.4 0.1 0.25 11.0 0.0 2.2 1 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.6 CCC67217.1 - 0.042 12.9 0.1 0.084 11.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DLH PF01738.13 CCC67217.1 - 0.09 12.0 0.0 0.21 10.8 0.0 1.6 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 CCC67217.1 - 0.12 11.9 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 alpha/beta hydrolase fold Nramp PF01566.13 CCC67218.1 - 5.3e-94 314.9 13.5 6.9e-94 314.5 9.3 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein COX5A PF02284.11 CCC67219.1 - 4.2e-49 164.9 1.3 5.5e-49 164.6 0.9 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va R3H-assoc PF13902.1 CCC67219.1 - 0.043 13.7 0.1 0.082 12.8 0.0 1.4 2 0 0 2 2 2 0 R3H-associated N-terminal domain Elf1 PF05129.8 CCC67220.1 - 3.1e-31 106.9 2.6 4.1e-31 106.5 1.8 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Ribosomal_L37ae PF01780.14 CCC67220.1 - 0.027 14.3 1.3 0.045 13.6 0.9 1.3 1 0 0 1 1 1 0 Ribosomal L37ae protein family CDC45 PF02724.9 CCC67220.1 - 0.12 10.4 2.4 0.14 10.2 1.6 1.0 1 0 0 1 1 1 0 CDC45-like protein zf-C2H2_6 PF13912.1 CCC67220.1 - 0.14 12.0 0.3 0.14 12.0 0.2 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CCC67220.1 - 0.32 11.1 3.3 2.9 8.0 0.4 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) A2L_zn_ribbon PF08792.5 CCC67220.1 - 0.71 9.4 4.0 3 7.4 0.3 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain Ribosomal_L44 PF00935.14 CCC67220.1 - 9 6.3 7.9 6.3 6.8 1.8 2.3 1 1 1 2 2 2 0 Ribosomal protein L44 Ribosomal_L1 PF00687.16 CCC67221.1 - 2.1e-41 141.7 6.8 2.1e-41 141.7 4.7 1.9 2 1 1 3 3 3 1 Ribosomal protein L1p/L10e family GCR1_C PF12550.3 CCC67222.1 - 1.7e-07 31.0 0.0 4.3e-07 29.7 0.0 1.8 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes Ribosomal_S13 PF00416.17 CCC67222.1 - 0.062 13.7 0.3 0.21 12.0 0.1 2.1 2 1 0 2 2 2 0 Ribosomal protein S13/S18 TBPIP PF07106.8 CCC67222.1 - 0.086 12.3 3.1 0.31 10.5 0.1 2.5 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Aldo_ket_red PF00248.16 CCC67224.1 - 1.9e-48 164.6 0.0 2.5e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PIF1 PF05970.9 CCC67225.1 - 1.5e-52 178.7 2.8 5.5e-50 170.3 1.9 2.3 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 CCC67225.1 - 1.7e-16 60.4 0.1 6.2e-16 58.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCC67225.1 - 3.1e-05 24.1 0.0 0.00012 22.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCC67225.1 - 0.00085 19.0 0.7 0.0019 17.9 0.5 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 CCC67225.1 - 0.0019 18.3 0.1 0.0072 16.5 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 CCC67225.1 - 0.002 17.0 0.8 0.0043 15.9 0.5 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein UvrD_C_2 PF13538.1 CCC67225.1 - 0.0031 17.6 0.0 0.16 12.0 0.0 3.1 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 CCC67225.1 - 0.016 14.4 0.0 0.038 13.2 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF3533 PF12051.3 CCC67225.1 - 9.9 4.7 6.2 11 4.6 1.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) Pkinase PF00069.20 CCC67226.1 - 4.5e-69 232.4 0.3 1.3e-68 230.9 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67226.1 - 1.6e-30 106.0 0.4 2.8e-30 105.2 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Prok-TraM PF09228.5 CCC67226.1 - 0.015 15.4 1.2 0.74 10.0 0.5 2.6 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM Spt20 PF12090.3 CCC67226.1 - 0.026 13.8 6.2 0.053 12.8 4.3 1.4 1 0 0 1 1 1 0 Spt20 family APH PF01636.18 CCC67226.1 - 0.041 13.6 0.8 0.1 12.3 0.1 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family PhzC-PhzF PF02567.11 CCC67227.1 - 6.6e-55 186.3 0.0 7.7e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein Pro_racemase PF05544.6 CCC67227.1 - 0.0035 16.2 0.0 0.013 14.3 0.0 1.8 1 1 1 2 2 2 1 Proline racemase Pro_isomerase PF00160.16 CCC67228.1 - 3.9e-43 147.3 0.2 4.6e-43 147.1 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Zn_clus PF00172.13 CCC67229.1 - 1.2e-08 34.7 8.4 2e-08 33.9 5.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PC_rep PF01851.17 CCC67230.1 - 2.8e-26 90.2 17.1 2.7e-07 30.4 0.1 9.4 11 0 0 11 11 11 6 Proteasome/cyclosome repeat ATP-synt_C PF00137.16 CCC67231.1 - 4e-26 90.7 34.6 1.3e-18 66.6 5.7 2.6 3 0 0 3 3 3 2 ATP synthase subunit C GHMP_kinases_N PF00288.21 CCC67232.1 - 2.2e-13 50.0 0.0 4.2e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCC67232.1 - 0.00016 21.8 0.0 0.0004 20.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Peptidase_M16_C PF05193.16 CCC67233.1 - 5.3e-46 156.6 0.0 1.2e-45 155.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCC67233.1 - 9e-46 155.3 0.1 2.3e-43 147.5 0.0 2.2 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Myosin_head PF00063.16 CCC67234.1 - 1.2e-252 840.0 17.1 1.2e-252 840.0 11.9 4.0 3 1 2 5 5 5 1 Myosin head (motor domain) AAA_19 PF13245.1 CCC67234.1 - 0.27 10.9 0.0 0.79 9.5 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain F-box PF00646.28 CCC67235.1 - 0.049 13.2 0.1 0.18 11.4 0.0 1.9 1 0 0 1 1 1 0 F-box domain Ras PF00071.17 CCC67236.1 - 2.5e-20 72.4 0.7 1.3e-15 57.1 0.4 2.3 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CCC67236.1 - 1.9e-17 63.8 0.1 7.8e-11 42.5 0.1 2.5 1 1 0 2 2 2 2 Miro-like protein GTP_EFTU PF00009.22 CCC67236.1 - 5.6e-06 25.9 0.1 0.00088 18.7 0.1 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCC67236.1 - 0.00013 21.2 0.5 0.022 13.9 0.6 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 CCC67236.1 - 0.00047 19.6 0.0 0.22 10.9 0.0 2.4 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation Ribosomal_S27e PF01667.12 CCC67237.1 - 1e-29 101.7 3.5 1.4e-29 101.3 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CCC67237.1 - 8.1e-05 22.4 0.6 0.0001 22.1 0.4 1.1 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 CCC67237.1 - 0.051 12.9 3.8 0.074 12.3 2.6 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 CCC67237.1 - 0.13 11.8 1.3 6.2 6.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CCC67237.1 - 0.14 11.8 1.3 6.3 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain NIF PF03031.13 CCC67238.1 - 4e-50 169.5 0.1 8.5e-50 168.5 0.0 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Abhydro_lipase PF04083.11 CCC67239.1 - 7.4e-17 60.4 0.0 1.5e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CCC67239.1 - 4.8e-05 23.3 0.0 6.3e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_2 PF01674.13 CCC67239.1 - 0.002 17.4 0.0 0.0034 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) DUF900 PF05990.7 CCC67239.1 - 0.0048 16.2 0.0 0.007 15.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.15 CCC67239.1 - 0.062 12.8 0.0 0.096 12.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 CCC67239.1 - 0.082 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase PUF PF00806.14 CCC67240.1 - 4e-57 186.6 16.0 2.1e-07 30.0 0.1 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Rab5ip PF07019.7 CCC67241.1 - 1.6e-16 60.1 3.9 1.9e-16 59.9 2.7 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF383 PF04063.9 CCC67242.1 - 4.7e-69 231.7 0.2 2e-68 229.7 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 CCC67242.1 - 2.3e-24 84.7 0.0 6.6e-24 83.2 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF384) HEAT_2 PF13646.1 CCC67242.1 - 0.084 13.1 0.0 0.95 9.7 0.0 2.8 4 0 0 4 4 4 0 HEAT repeats ANAPC15 PF15243.1 CCC67242.1 - 0.46 10.5 11.4 1.3 9.0 7.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 DUF2457 PF10446.4 CCC67242.1 - 0.55 8.8 16.4 0.76 8.4 11.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) NOA36 PF06524.7 CCC67242.1 - 1 8.5 6.0 1.8 7.7 4.2 1.4 1 0 0 1 1 1 0 NOA36 protein Nop14 PF04147.7 CCC67242.1 - 1.6 6.5 8.6 2.1 6.1 5.9 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 CCC67242.1 - 2.5 7.6 9.7 4.3 6.8 6.7 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Nucleoplasmin PF03066.10 CCC67242.1 - 2.7 7.4 15.4 5.3 6.5 10.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 CCC67242.1 - 8.3 6.1 8.7 25 4.6 6.0 1.8 1 0 0 1 1 1 0 RXT2-like, N-terminal TFIIF_alpha PF05793.7 CCC67243.1 - 3e-10 39.1 0.8 3e-10 39.1 0.6 3.0 3 1 1 4 4 4 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-UBR PF02207.15 CCC67244.1 - 4.9e-17 61.4 15.2 4.9e-17 61.4 10.5 2.5 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 CCC67244.1 - 1.6e-07 30.9 0.0 4.1e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 CCC67244.1 - 0.00056 19.6 0.8 0.00056 19.6 0.6 3.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCC67244.1 - 0.001 19.0 1.3 0.001 19.0 0.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UCR_UQCRX_QCR9 PF05365.7 CCC67245.1 - 3.2e-28 97.1 3.5 3.5e-28 96.9 2.4 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like TspO_MBR PF03073.10 CCC67245.1 - 0.12 11.9 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 TspO/MBR family zf-Tim10_DDP PF02953.10 CCC67246.1 - 6.4e-18 63.8 2.3 8.9e-18 63.3 1.6 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ribonuc_red_sm PF00268.16 CCC67247.1 - 2.7e-77 259.5 2.4 3.3e-77 259.2 1.7 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain LsmAD PF06741.8 CCC67249.1 - 7.4e-29 99.6 0.6 7.4e-29 99.6 0.4 2.3 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 CCC67249.1 - 2.5e-20 72.1 0.4 7.6e-19 67.4 0.0 2.7 2 0 0 2 2 2 1 Ataxin 2 SM domain LSM14 PF12701.2 CCC67249.1 - 0.0019 17.9 0.1 0.036 13.8 0.0 2.7 2 0 0 2 2 2 1 Scd6-like Sm domain DUF1700 PF08006.6 CCC67249.1 - 0.36 10.0 0.3 0.67 9.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) AATase PF07247.7 CCC67250.1 - 9e-138 459.7 2.1 1.1e-137 459.5 1.5 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Chordopox_A15 PF05846.7 CCC67250.1 - 0.015 15.3 0.3 0.042 13.8 0.1 1.8 2 0 0 2 2 2 0 Chordopoxvirus A15 protein TnpV PF14198.1 CCC67250.1 - 0.068 13.0 0.1 6.2 6.7 0.0 2.4 2 0 0 2 2 2 0 Transposon-encoded protein TnpV SE PF08491.5 CCC67251.1 - 6.8e-120 399.0 0.0 8.8e-120 398.6 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 CCC67251.1 - 2e-10 40.2 0.0 7.3e-10 38.4 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCC67251.1 - 1.4e-05 24.1 0.1 4.4e-05 22.5 0.2 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 CCC67251.1 - 0.00056 19.0 0.1 0.0009 18.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 CCC67251.1 - 0.0012 18.7 0.4 0.0028 17.5 0.1 1.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCC67251.1 - 0.003 17.5 0.1 0.0067 16.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCC67251.1 - 0.0031 17.8 1.7 0.0053 17.1 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 CCC67251.1 - 0.0093 15.6 0.3 0.014 15.0 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 CCC67251.1 - 0.012 14.5 0.9 0.019 13.8 0.6 1.3 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 CCC67251.1 - 0.017 15.1 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDI PF00996.13 CCC67251.1 - 0.045 12.0 0.0 0.069 11.4 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor FAD_oxidored PF12831.2 CCC67251.1 - 0.068 12.2 0.2 0.13 11.3 0.2 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 CCC67251.1 - 0.13 10.7 1.4 1.2 7.5 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein CBP4 PF07960.6 CCC67252.1 - 3.5e-49 165.6 1.1 4e-49 165.4 0.8 1.0 1 0 0 1 1 1 1 CBP4 Translin PF01997.11 CCC67252.1 - 0.016 14.8 0.4 0.029 13.9 0.2 1.4 1 1 0 1 1 1 0 Translin family AAA_13 PF13166.1 CCC67252.1 - 0.066 11.6 2.3 0.079 11.4 1.6 1.0 1 0 0 1 1 1 0 AAA domain Kinesin-related PF06548.6 CCC67252.1 - 0.29 9.6 4.1 0.51 8.8 0.3 2.0 2 0 0 2 2 2 0 Kinesin-related DUF1366 PF07104.6 CCC67252.1 - 1.7 8.3 4.2 3.7 7.2 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) Flavodoxin_2 PF02525.12 CCC67253.1 - 1.6e-56 190.9 0.0 1.9e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCC67253.1 - 7.5e-14 51.5 0.0 1.3e-13 50.7 0.0 1.4 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CCC67253.1 - 0.0001 21.6 0.2 0.00021 20.6 0.2 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 CCC67254.1 - 7.2e-39 133.3 0.0 8.7e-39 133.0 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCC67254.1 - 2.4e-05 23.8 0.0 0.00034 20.1 0.0 2.2 2 0 0 2 2 2 1 NADPH-dependent FMN reductase Yip1 PF04893.12 CCC67255.1 - 4.4e-14 52.3 12.6 6.2e-14 51.8 8.7 1.3 1 0 0 1 1 1 1 Yip1 domain tRNA-synt_1g PF09334.6 CCC67256.1 - 3e-106 355.3 0.2 5.6e-106 354.5 0.1 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 CCC67256.1 - 1.2e-24 86.3 0.0 7.5e-11 40.7 0.0 4.0 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CCC67256.1 - 4.7e-06 25.9 0.0 0.00036 19.7 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain PS_Dcarbxylase PF02666.10 CCC67257.1 - 2.2e-52 177.3 0.0 4.4e-52 176.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 CCC67257.1 - 9.6e-13 47.7 4.3 2.2e-08 33.8 0.1 2.9 2 0 0 2 2 2 2 C2 domain PseudoU_synth_2 PF00849.17 CCC67258.1 - 3.6e-26 91.9 0.0 8.3e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 RNA pseudouridylate synthase XPA_N PF01286.13 CCC67258.1 - 0.027 14.1 0.5 0.05 13.2 0.3 1.4 1 0 0 1 1 1 0 XPA protein N-terminal ATP_synt_H PF05493.8 CCC67259.1 - 8.9e-22 76.9 4.2 1e-21 76.7 2.9 1.0 1 0 0 1 1 1 1 ATP synthase subunit H GWT1 PF06423.7 CCC67259.1 - 0.00094 19.2 0.8 0.0011 19.0 0.5 1.0 1 0 0 1 1 1 1 GWT1 MgtE PF01769.11 CCC67259.1 - 0.0075 16.5 1.5 0.0078 16.5 1.0 1.0 1 0 0 1 1 1 1 Divalent cation transporter Cyt_c_ox_IV PF12270.3 CCC67259.1 - 0.0098 15.6 0.6 0.01 15.5 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF3624 PF12292.3 CCC67259.1 - 0.028 14.8 2.7 0.043 14.2 1.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3624) AzlD PF05437.7 CCC67259.1 - 0.033 14.1 2.7 0.047 13.6 0.1 2.0 1 1 1 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Git3 PF11710.3 CCC67259.1 - 0.036 13.6 0.5 0.04 13.4 0.3 1.0 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 UPF0104 PF03706.8 CCC67259.1 - 0.062 12.5 2.0 0.063 12.5 1.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) Glucos_trans_II PF14264.1 CCC67259.1 - 0.064 12.2 1.5 0.064 12.2 1.1 1.0 1 0 0 1 1 1 0 Glucosyl transferase GtrII 7TM-7TMR_HD PF07698.6 CCC67259.1 - 0.078 12.4 1.5 0.085 12.2 1.0 1.0 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase 2TM PF13239.1 CCC67259.1 - 0.088 12.8 1.8 0.1 12.6 1.2 1.1 1 0 0 1 1 1 0 2TM domain YfhO PF09586.5 CCC67259.1 - 0.17 9.8 0.9 0.18 9.8 0.6 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Renin_r PF07850.9 CCC67259.1 - 0.25 11.7 0.9 0.37 11.1 0.1 1.6 1 1 1 2 2 2 0 Renin receptor-like protein Bax1-I PF01027.15 CCC67259.1 - 0.27 10.7 3.4 0.29 10.7 2.4 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.1 CCC67259.1 - 0.28 10.5 2.1 0.29 10.5 1.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF1772 PF08592.6 CCC67259.1 - 1.1 8.9 4.8 1.3 8.6 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Clathrin_lg_ch PF01086.12 CCC67261.1 - 4.7e-57 193.5 24.2 5.4e-57 193.3 16.8 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF3154 PF11351.3 CCC67261.1 - 0.047 13.4 0.8 0.047 13.4 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Bcl-2 PF00452.14 CCC67261.1 - 0.072 13.2 0.2 0.27 11.3 0.2 2.0 1 1 0 1 1 1 0 Apoptosis regulator proteins, Bcl-2 family PUL PF08324.6 CCC67261.1 - 0.16 10.7 1.4 0.54 8.9 0.5 2.0 2 0 0 2 2 2 0 PUL domain CPDase PF07823.6 CCC67261.1 - 0.17 11.3 2.3 0.28 10.6 1.5 1.4 1 1 0 1 1 1 0 Cyclic phosphodiesterase-like protein DUF3140 PF11338.3 CCC67261.1 - 0.95 9.6 4.8 1.3 9.2 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3140) Trs65 PF12735.2 CCC67262.1 - 1.5e-44 152.5 11.6 1.5e-44 152.5 8.0 2.2 1 1 1 2 2 2 1 TRAPP trafficking subunit Trs65 Bot1p PF12298.3 CCC67263.1 - 5.1e-64 215.3 0.2 5.1e-64 215.3 0.1 1.5 2 0 0 2 2 2 1 Eukaryotic mitochondrial regulator protein Sad1_UNC PF07738.8 CCC67264.1 - 2.4e-07 30.6 1.0 7.3e-05 22.5 0.1 3.0 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal ARGLU PF15346.1 CCC67264.1 - 0.00035 20.3 0.7 0.00088 19.0 0.5 1.6 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 Ogr_Delta PF04606.7 CCC67264.1 - 0.15 11.7 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Cpn60_TCP1 PF00118.19 CCC67265.1 - 2.3e-153 511.3 2.3 2.6e-153 511.1 1.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Mad3_BUB1_I PF08311.7 CCC67266.1 - 1.3e-28 99.3 0.2 3.3e-28 97.9 0.2 1.8 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 CCC67266.1 - 2.2e-23 81.8 0.7 5.3e-23 80.6 0.5 1.7 1 0 0 1 1 1 1 Mad3/BUB1 homology region 2 Pkinase PF00069.20 CCC67266.1 - 4.1e-17 62.1 0.0 1.4e-16 60.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67266.1 - 4.2e-06 26.0 0.0 7.9e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC67266.1 - 0.032 13.1 0.0 0.054 12.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like MMR_HSR1 PF01926.18 CCC67267.1 - 6.5e-20 71.2 0.5 2e-19 69.6 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.16 CCC67267.1 - 5.5e-19 67.7 0.0 1.1e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CCC67267.1 - 4.5e-13 48.7 0.0 7.7e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCC67267.1 - 7.5e-05 22.6 0.4 0.041 13.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 CCC67267.1 - 0.00057 20.3 0.2 0.002 18.5 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein AIG1 PF04548.11 CCC67267.1 - 0.00093 18.3 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 AIG1 family SRPRB PF09439.5 CCC67267.1 - 0.0065 15.7 0.3 0.08 12.1 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MCM PF00493.18 CCC67267.1 - 0.0095 14.7 0.1 0.026 13.3 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family Ras PF00071.17 CCC67267.1 - 0.069 12.5 0.4 1.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Ras family Glyco_hydro_16 PF00722.16 CCC67268.1 - 2.3e-44 150.9 1.0 2.3e-44 150.9 0.7 2.5 2 1 0 2 2 2 1 Glycosyl hydrolases family 16 Dicty_REP PF05086.7 CCC67268.1 - 1.3 6.6 17.0 1.8 6.2 11.8 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein AA_permease PF00324.16 CCC67269.1 - 4.8e-134 447.2 33.4 6.1e-134 446.9 23.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC67269.1 - 2.1e-37 128.6 37.4 2.6e-37 128.3 25.9 1.0 1 0 0 1 1 1 1 Amino acid permease E1-E2_ATPase PF00122.15 CCC67269.1 - 0.42 9.6 0.0 0.42 9.6 0.0 2.5 2 1 2 4 4 4 0 E1-E2 ATPase Ribosomal_L20 PF00453.13 CCC67270.1 - 0.012 15.5 0.1 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L20 DUF2207 PF09972.4 CCC67270.1 - 0.43 9.1 2.5 0.79 8.2 1.7 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2721 PF11026.3 CCC67270.1 - 0.78 9.3 7.3 19 4.8 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2721) EIF_2_alpha PF07541.7 CCC67271.1 - 1.9e-40 137.1 1.3 3.3e-40 136.3 0.2 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CCC67271.1 - 6e-14 51.8 1.0 1.6e-13 50.5 0.7 1.7 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 CCC67271.1 - 0.052 13.5 0.2 0.13 12.2 0.1 1.8 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 Viral_env_E26 PF11050.3 CCC67271.1 - 0.069 12.3 1.0 0.34 10.0 0.1 2.1 2 0 0 2 2 2 0 Virus envelope protein E26 Gp_dh_C PF02800.15 CCC67272.1 - 1.5e-74 248.7 0.2 2.7e-74 247.8 0.1 1.5 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CCC67272.1 - 2.6e-59 199.5 0.3 4.9e-59 198.6 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2436 PF10365.4 CCC67272.1 - 0.0091 15.6 0.2 0.016 14.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2436) DapB_N PF01113.15 CCC67272.1 - 0.021 14.7 1.0 0.048 13.5 0.1 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Biotin_lipoyl PF00364.17 CCC67273.1 - 8.5e-20 70.1 0.5 2e-19 69.0 0.3 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Bot1p PF12298.3 CCC67273.1 - 0.013 15.4 2.3 1.5 8.7 0.0 2.6 3 0 0 3 3 3 0 Eukaryotic mitochondrial regulator protein E3_binding PF02817.12 CCC67273.1 - 0.042 13.4 0.0 0.098 12.3 0.0 1.6 1 0 0 1 1 1 0 e3 binding domain HlyD_3 PF13437.1 CCC67273.1 - 0.32 11.3 2.7 5.2 7.4 0.0 2.8 2 1 1 3 3 3 0 HlyD family secretion protein WD40 PF00400.27 CCC67274.1 - 7.3e-09 35.1 1.4 7.6e-07 28.7 0.1 4.2 5 1 0 5 5 5 1 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 CCC67274.1 - 0.0086 14.4 0.0 0.33 9.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain Cadherin_pro PF08758.6 CCC67274.1 - 0.1 12.3 0.0 4.9 6.9 0.0 2.5 2 0 0 2 2 2 0 Cadherin prodomain like Me-amine-dh_H PF06433.6 CCC67274.1 - 0.11 11.0 0.0 0.36 9.4 0.0 1.8 1 1 1 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) Orthopox_B11R PF07033.6 CCC67274.1 - 0.23 10.9 1.2 14 5.2 0.1 2.8 3 0 0 3 3 3 0 Orthopoxvirus B11R protein FGGY_N PF00370.16 CCC67275.1 - 1.8e-23 83.1 0.0 3.9e-13 49.2 0.0 2.5 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 CCC67275.1 - 4.7e-16 58.9 0.0 9.3e-15 54.7 0.0 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DUF3533 PF12051.3 CCC67277.1 - 3.1e-125 417.8 16.5 3.1e-125 417.8 11.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.7 CCC67277.1 - 0.13 11.8 1.9 0.18 11.4 0.0 2.1 2 0 0 2 2 2 0 CDR ABC transporter TPR_11 PF13414.1 CCC67278.1 - 7.8e-06 25.4 12.7 0.2 11.2 0.1 5.3 5 0 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 CCC67278.1 - 1.4e-05 24.5 12.5 0.14 12.1 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCC67278.1 - 9.7e-05 22.9 0.1 0.11 13.2 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCC67278.1 - 0.00073 19.0 7.9 1.4 8.6 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCC67278.1 - 0.002 18.0 9.7 0.78 9.7 0.2 4.4 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCC67278.1 - 0.0058 16.3 20.0 0.14 12.0 0.2 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat Epimerase PF01370.16 CCC67279.1 - 2.3e-18 66.5 0.0 3.3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCC67279.1 - 1.4e-13 50.2 0.1 1.9e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCC67279.1 - 2.4e-09 36.4 0.0 6.6e-09 35.0 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CCC67279.1 - 5.8e-09 36.2 0.0 1.4e-08 34.9 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCC67279.1 - 0.00015 21.0 0.6 0.014 14.6 0.0 2.7 3 0 0 3 3 3 1 NmrA-like family adh_short PF00106.20 CCC67279.1 - 0.00056 19.8 0.1 0.0094 15.8 0.0 2.3 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCC67279.1 - 0.0022 16.9 0.3 0.02 13.8 0.1 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 CCC67279.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 CCC67279.1 - 0.082 13.2 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF3533 PF12051.3 CCC67280.1 - 4.7e-115 384.3 24.7 5.8e-115 384.0 17.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) PDR_CDR PF06422.7 CCC67280.1 - 0.18 11.4 0.0 0.18 11.4 0.0 2.4 3 0 0 3 3 3 0 CDR ABC transporter tRNA_SAD PF07973.9 CCC67282.1 - 5.6e-07 29.3 0.3 1.7e-06 27.8 0.2 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 CCC67282.1 - 3.6e-05 22.2 0.1 9.1e-05 20.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class II (A) PMT PF02366.13 CCC67284.1 - 8.7e-84 280.6 21.8 8.7e-84 280.6 15.1 2.1 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCC67284.1 - 1.3e-22 80.2 0.9 2.2e-22 79.5 0.6 1.4 1 0 0 1 1 1 1 MIR domain AzlD PF05437.7 CCC67284.1 - 9.1 6.2 13.6 9.8 6.1 1.1 3.8 3 2 1 4 4 4 0 Branched-chain amino acid transport protein (AzlD) WD40 PF00400.27 CCC67285.1 - 2e-65 214.4 22.9 2.4e-10 39.8 0.1 11.7 12 0 0 12 12 12 10 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCC67285.1 - 1.2e-05 25.0 0.5 0.63 9.8 0.0 5.1 3 2 2 5 5 5 3 Ciliary BBSome complex subunit 2, middle region YmzC PF14157.1 CCC67285.1 - 0.0032 17.2 0.6 9.5 6.1 0.1 3.8 3 0 0 3 3 3 1 YmzC-like protein Lactonase PF10282.4 CCC67285.1 - 0.18 10.8 0.0 2.7 6.9 0.0 2.5 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Rhodanese PF00581.15 CCC67286.1 - 6.8e-12 45.7 0.1 8.8e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain FTHFS PF01268.14 CCC67287.1 - 2.3e-257 854.4 0.4 3.4e-257 853.9 0.3 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CCC67287.1 - 1.1e-62 209.8 2.3 1.6e-62 209.3 0.2 2.3 3 0 0 3 3 3 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CCC67287.1 - 2.8e-39 133.7 1.1 6.2e-39 132.6 0.7 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AdoHcyase_NAD PF00670.16 CCC67287.1 - 0.0014 18.5 0.3 0.07 12.9 0.2 2.9 1 1 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain GTP_EFTU PF00009.22 CCC67287.1 - 0.099 12.0 0.8 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Helicase_C_4 PF13871.1 CCC67287.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Helicase_C-like AAA_17 PF13207.1 CCC67288.1 - 0.00026 21.8 0.1 0.00066 20.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 CCC67288.1 - 0.0007 19.0 0.0 0.00099 18.6 0.0 1.2 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.1 CCC67288.1 - 0.0026 18.0 0.1 0.0048 17.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC67288.1 - 0.004 17.1 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 CCC67288.1 - 0.014 14.5 0.0 0.021 13.9 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.1 CCC67288.1 - 0.029 14.2 0.0 0.064 13.1 0.0 1.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CCC67288.1 - 0.042 14.0 0.0 0.12 12.5 0.0 1.8 1 1 0 1 1 1 0 RNA helicase PIF1 PF05970.9 CCC67288.1 - 0.09 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase AAA_22 PF13401.1 CCC67288.1 - 0.091 12.8 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cobl PF09469.5 CCC67288.1 - 0.097 12.6 0.0 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain Collagen PF01391.13 CCC67289.1 - 9.4e-09 34.6 56.3 2.2e-06 27.1 18.6 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Glutenin_hmw PF03157.8 CCC67289.1 - 0.00098 17.5 37.2 0.0013 17.0 25.8 1.0 1 0 0 1 1 1 1 High molecular weight glutenin subunit Plasmodium_HRP PF05403.6 CCC67289.1 - 0.32 10.5 4.2 0.47 10.0 2.9 1.1 1 0 0 1 1 1 0 Plasmodium histidine-rich protein (HRPII/III) Mvb12 PF09452.5 CCC67290.1 - 1.3e-35 121.4 0.1 1.7e-35 121.0 0.1 1.2 1 0 0 1 1 1 1 ESCRT-I subunit Mvb12 Peptidase_S80 PF07230.6 CCC67290.1 - 0.0056 15.0 0.0 0.0075 14.6 0.0 1.1 1 0 0 1 1 1 1 Bacteriophage T4-like capsid assembly protein (Gp20) Nucleopor_Nup85 PF07575.8 CCC67290.1 - 0.0093 14.2 0.0 0.011 13.9 0.0 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin ETF PF01012.16 CCC67291.1 - 8.7e-31 106.8 0.0 1.1e-30 106.4 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain HAD PF12710.2 CCC67292.1 - 3.5e-14 53.4 0.1 5.4e-14 52.7 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC67292.1 - 1.4e-10 41.9 0.1 1.1e-08 35.7 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCC67292.1 - 3.4e-09 36.6 0.0 2.2e-07 30.7 0.0 2.7 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF705 PF05152.7 CCC67292.1 - 0.005 15.8 0.1 0.0069 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) HAD_2 PF13419.1 CCC67292.1 - 0.044 13.9 0.0 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase TetR_C_3 PF08362.6 CCC67292.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 YcdC-like protein, C-terminal region Thioredoxin PF00085.15 CCC67293.1 - 9.2e-31 105.6 0.7 1.3e-30 105.1 0.5 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCC67293.1 - 2.8e-08 33.9 0.3 3.1e-07 30.5 0.2 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 CCC67293.1 - 1.7e-07 30.8 0.1 2e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 CCC67293.1 - 3.2e-06 27.1 0.1 8e-05 22.6 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 CCC67293.1 - 4.4e-05 23.1 0.2 6e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.11 CCC67293.1 - 0.00011 21.6 0.1 0.00015 21.3 0.0 1.1 1 0 0 1 1 1 1 Mitosis protein DIM1 Redoxin PF08534.5 CCC67293.1 - 0.00094 18.7 0.1 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 CCC67293.1 - 0.0023 17.9 0.1 0.0038 17.2 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 CCC67293.1 - 0.0048 16.4 0.2 0.0065 15.9 0.1 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein HyaE PF07449.6 CCC67293.1 - 0.064 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE MMR_HSR1_C PF08438.5 CCC67294.1 - 4.7e-33 113.6 0.0 7.5e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 CCC67294.1 - 1.1e-17 64.0 0.0 2.4e-17 62.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCC67294.1 - 4.2e-07 29.3 0.1 1.5e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CCC67294.1 - 0.00053 19.4 0.1 0.4 10.0 0.0 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_10 PF12846.2 CCC67294.1 - 0.0018 17.7 0.0 0.017 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain ATP_bind_1 PF03029.12 CCC67294.1 - 0.0091 15.5 0.1 1.8 8.0 0.0 2.3 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 CCC67294.1 - 0.014 15.2 0.2 0.078 12.7 0.0 2.3 3 1 1 4 4 4 0 Dynamin family AAA_17 PF13207.1 CCC67294.1 - 0.025 15.3 0.5 0.22 12.3 0.1 2.7 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCC67294.1 - 0.055 13.0 0.2 2.9 7.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArgK PF03308.11 CCC67294.1 - 0.066 11.9 0.5 0.26 10.0 0.0 2.2 3 0 0 3 3 3 0 ArgK protein FtsK_SpoIIIE PF01580.13 CCC67294.1 - 0.16 11.4 0.0 0.38 10.2 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family RSF PF14876.1 CCC67295.1 - 6.4e-12 44.9 1.0 1.4e-11 43.8 0.7 1.5 1 0 0 1 1 1 1 Respiratory growth transcriptional regulator TFIIA PF03153.8 CCC67295.1 - 0.002 18.1 37.0 0.0037 17.2 25.6 1.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF1510 PF07423.6 CCC67295.1 - 0.0044 16.4 5.1 0.0044 16.4 3.6 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1510) Androgen_recep PF02166.11 CCC67295.1 - 0.05 12.4 5.0 0.075 11.8 3.5 1.2 1 0 0 1 1 1 0 Androgen receptor zf-ZPR1 PF03367.8 CCC67296.1 - 1.2e-119 395.1 2.8 4.4e-59 198.2 0.1 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.14 CCC67296.1 - 0.0027 17.3 2.8 1.1 8.9 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Lar_restr_allev PF14354.1 CCC67296.1 - 0.038 14.2 2.9 2.1 8.6 0.7 3.3 3 0 0 3 3 3 0 Restriction alleviation protein Lar TniQ PF06527.6 CCC67296.1 - 0.091 12.9 0.3 0.71 10.0 0.1 2.1 2 0 0 2 2 2 0 TniQ Zn-ribbon_8 PF09723.5 CCC67296.1 - 0.44 10.5 8.3 6.8 6.7 0.0 4.3 4 0 0 4 4 4 0 Zinc ribbon domain AATase PF07247.7 CCC67297.1 - 3.8e-64 216.9 3.1 4.7e-64 216.6 2.2 1.0 1 0 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 CCC67297.1 - 4.9e-08 32.1 0.1 0.00027 19.8 0.1 2.1 2 0 0 2 2 2 2 Condensation domain HTH_34 PF13601.1 CCC67297.1 - 0.12 12.4 0.1 0.65 10.0 0.0 2.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain RTA1 PF04479.8 CCC67298.1 - 5.4e-83 277.9 10.8 5.4e-83 277.9 7.5 1.7 2 0 0 2 2 2 1 RTA1 like protein DUF373 PF04123.8 CCC67298.1 - 3.2 6.6 9.3 0.42 9.5 1.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Ribosomal_S2 PF00318.15 CCC67299.1 - 4.5e-41 140.4 0.0 5.7e-21 74.7 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 MRP-S33 PF08293.6 CCC67300.1 - 2.4e-32 110.7 0.2 3e-32 110.4 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Gpi1 PF05024.10 CCC67301.1 - 2e-51 174.3 16.5 2e-51 174.3 11.5 2.2 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Ion_trans PF00520.26 CCC67302.1 - 1.1e-83 279.4 109.3 6.3e-31 107.1 4.5 5.6 5 1 0 5 5 5 4 Ion transport protein CRM1_C PF08767.6 CCC67303.1 - 2.5e-128 427.5 6.1 2.5e-128 427.5 4.2 2.7 3 0 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 CCC67303.1 - 3.4e-37 127.6 12.5 1e-36 126.0 5.3 3.7 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 CCC67303.1 - 1.5e-13 50.4 0.1 7.4e-13 48.2 0.0 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Ribosomal_L3 PF00297.17 CCC67304.1 - 1.3e-41 142.7 2.4 1.4e-40 139.3 1.7 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 DUF3589 PF12141.3 CCC67305.1 - 7.3e-82 275.1 4.7 6.5e-81 272.0 3.3 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) Dimer_Tnp_hAT PF05699.9 CCC67306.1 - 7.7e-09 35.0 0.2 3e-08 33.1 0.1 2.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 CCC67306.1 - 0.021 14.5 0.6 0.052 13.3 0.4 1.7 1 0 0 1 1 1 0 BED zinc finger Miro PF08477.8 CCC67307.1 - 4.7e-42 143.2 0.0 5.1e-21 75.3 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 CCC67307.1 - 5.2e-28 96.6 0.2 8.3e-27 92.7 0.0 2.7 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.7 CCC67307.1 - 2.5e-27 93.9 1.0 5.7e-27 92.8 0.7 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 CCC67307.1 - 1.3e-24 86.4 0.0 8.6e-12 44.7 0.0 2.4 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 CCC67307.1 - 7.7e-09 35.5 0.0 0.00011 22.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 CCC67307.1 - 4.1e-08 33.2 1.0 0.0049 16.9 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCC67307.1 - 2.7e-07 29.9 1.4 0.00026 20.6 0.0 3.4 3 0 0 3 3 2 1 EF-hand domain EF-hand_1 PF00036.27 CCC67307.1 - 9.7e-07 27.6 8.6 9.8e-05 21.3 0.2 3.6 4 0 0 4 4 3 2 EF hand EF-hand_8 PF13833.1 CCC67307.1 - 4.8e-06 26.0 0.6 0.0022 17.5 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair Dynamin_N PF00350.18 CCC67307.1 - 6.1e-05 22.9 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_16 PF13191.1 CCC67307.1 - 6.4e-05 23.0 0.0 0.17 11.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain MobB PF03205.9 CCC67307.1 - 0.00024 20.8 0.1 0.67 9.6 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 CCC67307.1 - 0.00024 20.6 0.0 0.2 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain GTP_EFTU PF00009.22 CCC67307.1 - 0.00026 20.4 0.0 0.52 9.7 0.0 3.3 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain EF-hand_5 PF13202.1 CCC67307.1 - 0.00028 20.0 4.1 0.00049 19.3 0.7 2.7 2 0 0 2 2 2 1 EF hand Arf PF00025.16 CCC67307.1 - 0.00038 19.7 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 1 1 ADP-ribosylation factor family AAA_29 PF13555.1 CCC67307.1 - 0.0018 17.7 0.2 2.1 7.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CCC67307.1 - 0.0062 16.6 0.0 1.1 9.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.13 CCC67307.1 - 0.011 15.0 0.1 1.4 8.1 0.0 3.3 3 0 0 3 3 3 0 Ferrous iron transport protein B ABC_tran PF00005.22 CCC67307.1 - 0.012 15.9 0.2 2.9 8.1 0.2 2.4 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 CCC67307.1 - 0.013 15.0 0.0 0.48 9.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CCC67307.1 - 0.018 14.4 0.0 1.7 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 CCC67307.1 - 0.018 13.7 0.0 0.2 10.2 0.0 2.3 2 1 1 3 3 3 0 AAA domain DUF258 PF03193.11 CCC67307.1 - 0.022 13.9 0.1 0.22 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCC67307.1 - 0.023 14.9 0.1 5.1 7.4 0.0 3.0 3 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 CCC67307.1 - 0.027 14.6 0.0 5.3 7.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Septin PF00735.13 CCC67307.1 - 0.044 12.7 0.0 2.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Septin Arch_ATPase PF01637.13 CCC67307.1 - 0.062 12.9 0.0 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 CCC67307.1 - 0.084 12.3 0.2 11 5.4 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_17 PF13207.1 CCC67307.1 - 0.09 13.5 0.0 6 7.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 CCC67307.1 - 0.11 12.1 0.0 3.7 7.1 0.0 2.7 3 0 0 3 3 2 0 NACHT domain Mto2_bdg PF12808.2 CCC67308.1 - 3.4e-06 27.0 5.4 3.4e-06 27.0 3.7 3.8 2 1 1 3 3 3 1 Micro-tubular organiser Mto1 C-term Mto2-binding region bZIP_2 PF07716.10 CCC67308.1 - 0.016 15.0 4.6 0.016 15.0 3.2 6.0 5 1 0 5 5 5 0 Basic region leucine zipper BolA PF01722.13 CCC67309.1 - 2.8e-15 56.0 0.0 4.3e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein BolA PF01722.13 CCC67310.1 - 9.9e-23 79.9 0.6 1.2e-22 79.6 0.4 1.1 1 0 0 1 1 1 1 BolA-like protein Nup153 PF08604.5 CCC67310.1 - 0.011 14.4 0.1 0.014 14.1 0.1 1.0 1 0 0 1 1 1 0 Nucleoporin Nup153-like GCV_H PF01597.14 CCC67311.1 - 2.9e-45 152.8 0.3 3.4e-45 152.6 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 CCC67311.1 - 0.061 12.9 0.1 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 Biotin-requiring enzyme DUF3453 PF11935.3 CCC67312.1 - 4.4e-52 176.8 1.0 1.3e-51 175.3 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) DUF3210 PF11489.3 CCC67312.1 - 0.12 10.9 2.7 0.18 10.4 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) COPIIcoated_ERV PF07970.7 CCC67313.1 - 2e-64 217.2 1.3 2.6e-64 216.9 0.9 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCC67313.1 - 8.7e-32 108.9 0.3 2e-31 107.8 0.2 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CDC24 PF06395.6 CCC67314.1 - 2.3e-35 120.5 0.8 2.3e-35 120.5 0.6 2.1 2 0 0 2 2 2 1 CDC24 Calponin RhoGEF PF00621.15 CCC67314.1 - 1.1e-33 116.6 4.4 1.1e-33 116.6 3.1 2.1 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.1 CCC67314.1 - 1e-18 67.5 7.5 1.5e-09 38.0 0.6 3.5 2 1 1 3 3 3 2 Pleckstrin homology domain PB1 PF00564.19 CCC67314.1 - 2.6e-05 23.7 0.4 7.7e-05 22.2 0.3 1.9 1 0 0 1 1 1 1 PB1 domain Cyclin_N PF00134.18 CCC67315.1 - 1.6e-26 92.3 4.2 3.8e-26 91.1 2.9 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyto_heme_lyase PF01265.12 CCC67316.1 - 5.7e-70 235.8 0.6 6.4e-70 235.6 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase PK PF00224.16 CCC67317.1 - 6.8e-165 547.8 0.8 8.8e-165 547.4 0.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CCC67317.1 - 9.3e-29 99.3 0.0 3e-28 97.7 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CCC67317.1 - 3.4e-05 22.8 0.4 7.7e-05 21.6 0.1 1.7 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family Sulfotransfer_1 PF00685.22 CCC67317.1 - 0.17 11.1 0.0 0.55 9.4 0.0 1.8 3 0 0 3 3 3 0 Sulfotransferase domain Miro PF08477.8 CCC67318.1 - 2.7e-42 144.0 0.0 5.1e-21 75.3 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 CCC67318.1 - 5.2e-28 96.6 0.2 8.3e-27 92.7 0.0 2.7 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.7 CCC67318.1 - 2.5e-27 93.9 1.0 5.7e-27 92.8 0.7 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 CCC67318.1 - 7e-25 87.2 0.0 4.7e-12 45.5 0.0 2.4 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 CCC67318.1 - 1.1e-08 35.0 0.0 0.00011 22.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 CCC67318.1 - 4.1e-08 33.2 1.0 0.0049 16.9 0.1 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCC67318.1 - 2.7e-07 29.9 1.4 0.00026 20.6 0.0 3.4 3 0 0 3 3 2 1 EF-hand domain EF-hand_1 PF00036.27 CCC67318.1 - 9.7e-07 27.6 8.6 9.8e-05 21.3 0.2 3.6 4 0 0 4 4 3 2 EF hand EF-hand_8 PF13833.1 CCC67318.1 - 4.8e-06 26.0 0.6 0.0022 17.5 0.1 2.8 2 0 0 2 2 2 1 EF-hand domain pair Dynamin_N PF00350.18 CCC67318.1 - 6.5e-05 22.8 0.0 0.02 14.7 0.0 2.4 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.22 CCC67318.1 - 0.0002 20.8 0.0 0.52 9.7 0.0 3.3 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain MobB PF03205.9 CCC67318.1 - 0.00022 20.9 0.2 0.67 9.6 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CCC67318.1 - 0.00024 21.1 0.0 0.64 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 CCC67318.1 - 0.00027 20.4 0.0 0.2 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain EF-hand_5 PF13202.1 CCC67318.1 - 0.00028 20.0 4.1 0.00049 19.3 0.7 2.7 2 0 0 2 2 2 1 EF hand Arf PF00025.16 CCC67318.1 - 0.00037 19.7 0.0 0.0011 18.2 0.0 1.7 2 0 0 2 2 1 1 ADP-ribosylation factor family AAA_29 PF13555.1 CCC67318.1 - 0.0018 17.7 0.2 2.1 7.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CCC67318.1 - 0.0071 16.4 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CCC67318.1 - 0.0072 15.9 0.1 0.26 10.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.13 CCC67318.1 - 0.009 15.3 0.1 1.4 8.1 0.0 3.3 3 0 0 3 3 3 1 Ferrous iron transport protein B ABC_tran PF00005.22 CCC67318.1 - 0.012 15.8 0.2 2.9 8.1 0.2 2.4 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.1 CCC67318.1 - 0.02 14.3 0.0 2 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CCC67318.1 - 0.022 13.9 0.1 0.22 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCC67318.1 - 0.027 14.7 0.1 5.9 7.2 0.0 3.0 3 1 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 CCC67318.1 - 0.03 14.5 0.0 5.9 7.1 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_32 PF13654.1 CCC67318.1 - 0.03 12.9 0.0 0.2 10.2 0.0 2.1 2 1 1 3 3 3 0 AAA domain Septin PF00735.13 CCC67318.1 - 0.057 12.4 0.0 2.6 6.9 0.0 2.2 2 0 0 2 2 2 0 Septin AAA_17 PF13207.1 CCC67318.1 - 0.081 13.7 0.0 5.2 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 CCC67318.1 - 0.083 12.5 0.0 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 CCC67318.1 - 0.086 12.2 0.2 11 5.4 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family NACHT PF05729.7 CCC67318.1 - 0.13 11.9 0.0 4.3 6.9 0.0 2.7 3 0 0 3 3 2 0 NACHT domain Zn_clus PF00172.13 CCC67319.1 - 1.2e-10 41.1 10.7 2.2e-10 40.2 7.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRP PF06011.7 CCC67320.1 - 4e-157 523.2 40.2 5.1e-157 522.9 27.9 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCC67320.1 - 7e-44 149.3 4.0 1.3e-43 148.4 2.8 1.4 1 0 0 1 1 1 1 ML-like domain AMP-binding PF00501.23 CCC67321.1 - 1.4e-90 303.7 0.0 2e-90 303.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCC67321.1 - 1.2e-18 67.8 0.2 1.3e-17 64.5 0.1 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain HHH_2 PF12826.2 CCC67321.1 - 0.11 12.3 0.0 0.98 9.3 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif Kelch_4 PF13418.1 CCC67322.1 - 6.2e-10 38.7 3.9 4.2e-05 23.2 0.1 5.0 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CCC67322.1 - 5e-09 35.9 5.5 0.0044 17.1 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 CCC67322.1 - 6.2e-09 35.6 8.0 0.11 12.4 0.0 6.0 5 1 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 CCC67322.1 - 1.4e-06 28.3 0.4 0.18 12.0 0.0 5.5 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CCC67322.1 - 0.00015 21.1 6.0 0.95 9.0 0.1 4.7 4 0 0 4 4 4 2 Kelch motif Alb1 PF09135.6 CCC67323.1 - 6.2e-24 84.7 16.5 6.2e-24 84.7 11.4 1.6 2 0 0 2 2 2 1 Alb1 ADH_N PF08240.7 CCC67324.1 - 6.1e-31 106.4 4.3 1.2e-30 105.5 3.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCC67324.1 - 4.1e-23 81.3 0.0 7.2e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Shikimate_DH PF01488.15 CCC67324.1 - 0.0011 19.1 0.1 0.0026 17.8 0.0 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 CCC67324.1 - 0.01 16.0 0.0 0.02 15.1 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 CCC67324.1 - 0.023 14.7 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCC67324.1 - 0.038 14.3 0.4 2.1 8.7 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.16 CCC67324.1 - 0.73 9.6 3.8 0.38 10.5 0.1 2.2 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ADH_N PF08240.7 CCC67325.1 - 7.2e-34 115.8 2.6 1.4e-33 114.9 1.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCC67325.1 - 1.6e-23 82.6 0.0 3.2e-23 81.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 CCC67325.1 - 0.0037 16.3 0.8 0.0056 15.7 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 CCC67325.1 - 0.013 15.8 0.1 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CCC67325.1 - 0.035 14.2 0.7 0.072 13.1 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox_3 PF13738.1 CCC67325.1 - 0.039 14.0 1.6 0.042 13.9 0.3 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCC67325.1 - 0.046 12.6 0.2 0.074 11.9 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase MafB19-deam PF14437.1 CCC67325.1 - 0.054 13.1 0.2 0.4 10.3 0.1 2.2 2 0 0 2 2 2 0 MafB19-like deaminase ADH_zinc_N_2 PF13602.1 CCC67325.1 - 0.094 13.6 0.0 0.18 12.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 CCC67326.1 - 3.2e-77 259.4 7.6 4e-77 259.0 5.2 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 CCC67326.1 - 3.2e-46 156.1 0.0 7.5e-46 154.9 0.0 1.7 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain BTB PF00651.26 CCC67327.1 - 5.4e-28 97.1 0.1 2.1e-18 66.3 0.1 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.2 CCC67327.1 - 1.2e-10 41.5 0.0 1e-09 38.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCC67327.1 - 4.6e-09 36.5 0.0 1.6e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 CCC67327.1 - 4.9e-09 35.5 0.1 7.5e-06 25.4 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CCC67327.1 - 9.2e-08 31.6 0.2 0.002 18.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 CCC67327.1 - 1.8e-05 24.7 0.0 0.00014 21.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF3342 PF11822.3 CCC67327.1 - 0.0099 15.0 0.1 0.022 13.9 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3342) Herpes_BLRF2 PF05812.7 CCC67327.1 - 0.052 13.3 2.7 0.13 12.0 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein RRM_1 PF00076.17 CCC67328.1 - 1.5e-07 30.9 0.1 4.3e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC67328.1 - 3.9e-07 29.9 0.0 6.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC67328.1 - 4.3e-06 26.4 0.0 8.5e-06 25.5 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop16 PF09420.5 CCC67329.1 - 1.1e-58 197.9 13.1 1.3e-58 197.6 9.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 DUF2095 PF09868.4 CCC67329.1 - 0.032 14.0 3.5 0.049 13.3 2.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) SPK PF04435.13 CCC67329.1 - 0.11 12.5 0.9 0.43 10.5 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF545) DUF4047 PF13256.1 CCC67329.1 - 1.1 9.1 9.3 4.2 7.3 4.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4047) PMI_typeI PF01238.16 CCC67330.1 - 6.8e-158 525.5 0.0 7.8e-158 525.3 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I AraC_binding PF02311.14 CCC67330.1 - 6e-06 25.9 0.0 0.005 16.5 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain Cupin_2 PF07883.6 CCC67330.1 - 0.038 13.5 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Cupin domain UPF1_Zn_bind PF09416.5 CCC67331.1 - 4.5e-72 240.6 9.5 4.5e-72 240.6 6.6 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 CCC67331.1 - 6.5e-59 198.6 0.0 1.6e-58 197.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCC67331.1 - 2.8e-53 180.9 2.0 4.2e-53 180.3 1.4 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCC67331.1 - 2.7e-16 59.7 0.2 4.7e-12 45.8 0.1 2.2 1 1 1 2 2 2 2 AAA domain AAA_19 PF13245.1 CCC67331.1 - 2.1e-13 49.7 0.1 6.7e-13 48.1 0.1 1.8 2 0 0 2 2 2 1 Part of AAA domain DUF2075 PF09848.4 CCC67331.1 - 1.2e-06 27.7 0.1 1.2e-05 24.4 0.0 2.6 2 2 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 CCC67331.1 - 2.7e-06 27.0 0.0 0.13 11.8 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 CCC67331.1 - 2.8e-05 24.0 0.0 5.7e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 CCC67331.1 - 3e-05 23.4 0.6 0.02 14.1 0.0 2.9 2 1 0 3 3 3 2 UvrD/REP helicase N-terminal domain PIF1 PF05970.9 CCC67331.1 - 0.002 17.1 0.0 1 8.2 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase Helicase_RecD PF05127.9 CCC67331.1 - 0.0032 17.1 0.0 0.0071 16.0 0.0 1.6 1 0 0 1 1 1 1 Helicase DEAD PF00270.24 CCC67331.1 - 0.0085 15.5 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase PhoH PF02562.11 CCC67331.1 - 0.0089 15.2 0.0 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 CCC67331.1 - 0.019 13.9 0.0 0.031 13.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 CCC67331.1 - 0.04 13.9 0.2 0.04 13.9 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 CCC67331.1 - 0.061 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ribosomal_S13_N PF08069.7 CCC67331.1 - 0.12 12.1 0.0 0.54 10.1 0.0 2.1 2 0 0 2 2 1 0 Ribosomal S13/S15 N-terminal domain KaiC PF06745.8 CCC67331.1 - 0.14 11.2 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 KaiC Zip PF02535.17 CCC67332.1 - 0.8 8.6 4.6 1.1 8.2 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PIR PF00399.14 CCC67333.1 - 1.1e-06 27.7 8.4 4.8e-06 25.7 5.8 2.3 1 0 0 1 1 1 1 Yeast PIR protein repeat DUF4480 PF13715.1 CCC67333.1 - 0.038 14.0 0.8 4.2 7.4 0.5 2.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4480) 3D PF06725.6 CCC67333.1 - 1.7 8.6 5.0 1.9 8.5 0.1 2.9 2 1 1 3 3 3 0 3D domain Omp28 PF11551.3 CCC67333.1 - 2.5 7.6 7.4 5.3 6.5 4.0 2.0 1 1 1 2 2 2 0 Outer membrane protein Omp28 Peptidase_A22B PF04258.8 CCC67335.1 - 1.2e-56 192.4 14.7 2e-56 191.6 10.2 1.3 1 0 0 1 1 1 1 Signal peptide peptidase DUF4519 PF15012.1 CCC67335.1 - 0.11 12.3 0.4 0.44 10.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) ADH_N PF08240.7 CCC67336.1 - 1.1e-30 105.5 0.6 2e-30 104.7 0.4 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCC67336.1 - 3.5e-28 97.7 0.2 5.1e-28 97.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Macro_2 PF14519.1 CCC67338.1 - 3.3e-134 446.3 0.0 4e-134 446.1 0.0 1.0 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.16 CCC67338.1 - 0.053 13.4 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Macro domain MFS_1 PF07690.11 CCC67339.1 - 1.4e-39 135.8 35.3 1.4e-39 135.8 24.5 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCC67339.1 - 3.5e-15 55.5 6.5 3.5e-15 55.5 4.5 3.2 2 1 0 2 2 2 1 Sugar (and other) transporter Peptidase_M41 PF01434.13 CCC67340.1 - 1.1e-73 247.2 1.0 2.1e-73 246.3 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.24 CCC67340.1 - 2.5e-42 144.2 0.0 6.1e-42 142.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 CCC67340.1 - 6.4e-11 42.4 0.9 1.5e-10 41.1 0.6 1.7 1 0 0 1 1 1 1 FtsH Extracellular AAA_17 PF13207.1 CCC67340.1 - 6.1e-05 23.8 0.2 0.00051 20.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCC67340.1 - 0.00046 19.9 0.1 0.0019 17.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CCC67340.1 - 0.0023 16.9 0.0 0.0045 16.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 CCC67340.1 - 0.0023 17.8 0.1 0.0087 15.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 CCC67340.1 - 0.0025 16.6 0.0 0.0058 15.3 0.0 1.6 1 0 0 1 1 1 1 TIP49 C-terminus AAA_22 PF13401.1 CCC67340.1 - 0.0034 17.5 0.2 0.15 12.1 0.1 3.0 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.1 CCC67340.1 - 0.0038 16.9 0.4 0.011 15.4 0.3 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 CCC67340.1 - 0.0099 15.7 0.1 0.098 12.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCC67340.1 - 0.011 15.1 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 CCC67340.1 - 0.012 15.5 0.0 0.25 11.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 CCC67340.1 - 0.016 15.1 0.5 0.44 10.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CCC67340.1 - 0.026 14.8 0.6 0.29 11.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 CCC67340.1 - 0.083 12.8 2.0 0.11 12.4 0.2 2.2 2 1 0 2 2 1 0 AAA ATPase domain AAA_25 PF13481.1 CCC67340.1 - 0.55 9.6 6.6 0.27 10.6 0.4 3.0 2 1 1 3 3 3 0 AAA domain ING PF12998.2 CCC67340.1 - 2.3 8.5 7.6 9 6.6 1.9 2.9 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Sec7 PF01369.15 CCC67340.1 - 2.6 7.6 6.8 0.25 11.0 0.1 2.6 3 0 0 3 3 3 0 Sec7 domain NAD_binding_10 PF13460.1 CCC67341.1 - 9e-28 97.5 0.0 1.1e-27 97.2 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCC67341.1 - 6.7e-08 32.0 0.1 2.3e-07 30.2 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 CCC67341.1 - 1.9e-07 30.0 0.2 2.7e-07 29.5 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 CCC67341.1 - 1.1e-06 28.2 0.2 7.9e-06 25.4 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 CCC67341.1 - 2e-05 24.8 0.1 3.4e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CCC67341.1 - 6.3e-05 22.1 0.1 8.7e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 CCC67341.1 - 0.00017 21.4 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 CCC67341.1 - 0.00017 21.4 0.1 0.00027 20.7 0.1 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 CCC67341.1 - 0.016 15.7 0.0 0.029 14.8 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CRC_subunit PF08624.5 CCC67342.1 - 1.1e-51 174.4 0.0 2.1e-51 173.4 0.0 1.5 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit BUD22 PF09073.5 CCC67342.1 - 0.72 8.8 18.7 1 8.3 12.9 1.2 1 0 0 1 1 1 0 BUD22 WD40 PF00400.27 CCC67343.1 - 5.9e-29 98.8 19.0 0.00012 21.8 0.0 12.3 12 1 0 12 12 12 7 WD domain, G-beta repeat eIF2A PF08662.6 CCC67343.1 - 1.4e-05 24.8 0.3 0.12 12.0 0.0 3.9 3 2 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCC67343.1 - 0.032 12.3 1.6 0.087 10.9 0.8 1.8 1 1 1 2 2 2 0 Nucleoporin Nup120/160 UTP15_C PF09384.5 CCC67344.1 - 1.8e-53 180.2 0.9 2.7e-53 179.6 0.6 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 CCC67344.1 - 9.1e-21 72.9 11.0 4.4e-07 29.5 0.0 7.4 7 0 0 7 7 7 5 WD domain, G-beta repeat PHTB1_N PF14727.1 CCC67344.1 - 0.012 14.5 0.1 0.5 9.2 0.0 2.4 1 1 1 2 2 2 0 PTHB1 N-terminus MMR_HSR1 PF01926.18 CCC67346.1 - 1.3e-13 50.9 0.0 6.6e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCC67346.1 - 0.0003 20.0 0.0 0.00053 19.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 CCC67346.1 - 0.0015 18.2 0.2 0.0029 17.3 0.1 1.4 1 0 0 1 1 1 1 NTPase Dynamin_N PF00350.18 CCC67346.1 - 0.0028 17.4 0.0 0.8 9.5 0.0 2.4 1 1 1 2 2 2 1 Dynamin family AAA_29 PF13555.1 CCC67346.1 - 0.0028 17.1 0.0 0.0055 16.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FeoB_N PF02421.13 CCC67346.1 - 0.0079 15.4 0.1 0.02 14.1 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_18 PF13238.1 CCC67346.1 - 0.017 15.3 0.1 0.054 13.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CCC67346.1 - 0.021 15.6 0.3 0.14 12.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.22 CCC67346.1 - 0.026 13.9 0.2 0.22 10.9 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 CCC67346.1 - 0.042 13.8 0.1 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.9 CCC67346.1 - 0.061 13.0 0.1 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 CCC67346.1 - 0.072 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 CCC67346.1 - 0.085 12.3 0.1 0.81 9.1 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ArgK PF03308.11 CCC67346.1 - 0.1 11.3 0.2 0.23 10.2 0.1 1.6 1 1 0 1 1 1 0 ArgK protein AAA_25 PF13481.1 CCC67346.1 - 0.14 11.5 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain mRNA_stabil PF13929.1 CCC67347.1 - 3.7e-59 200.0 10.1 5.7e-59 199.4 7.0 1.2 1 0 0 1 1 1 1 mRNA stabilisation Oligomerisation PF02410.10 CCC67347.1 - 3e-09 36.8 0.0 7.2e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Oligomerisation domain zf-C2H2_4 PF13894.1 CCC67348.1 - 0.00092 19.3 14.6 0.0035 17.5 1.1 4.0 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CCC67348.1 - 0.001 19.2 3.0 0.001 19.2 2.1 4.3 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC67348.1 - 0.0013 18.8 0.9 0.0013 18.8 0.6 3.6 3 0 0 3 3 3 1 Zinc-finger double domain Serglycin PF04360.7 CCC67348.1 - 0.014 15.1 0.1 0.031 14.0 0.1 1.5 1 0 0 1 1 1 0 Serglycin zf-FCS PF06467.9 CCC67348.1 - 0.75 9.4 4.0 7.6 6.2 0.1 2.5 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-Di19 PF05605.7 CCC67348.1 - 1.5 8.9 6.5 0.69 10.0 2.1 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-DBF PF07535.7 CCC67348.1 - 3.6 7.3 6.2 2.3 7.9 0.6 2.9 3 0 0 3 3 3 0 DBF zinc finger PyrI_C PF02748.10 CCC67348.1 - 4.3 6.8 6.2 4.6 6.7 1.6 2.7 3 0 0 3 3 3 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-BED PF02892.10 CCC67348.1 - 6.3 6.6 8.4 0.54 10.0 0.9 2.7 3 0 0 3 3 3 0 BED zinc finger MRP-L28 PF09812.4 CCC67349.1 - 3.9e-29 101.5 1.1 4.9e-29 101.1 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Bul1_C PF04426.7 CCC67349.1 - 0.0056 15.9 0.5 0.0071 15.5 0.3 1.2 1 0 0 1 1 1 1 Bul1 C terminus DUF413 PF04219.7 CCC67349.1 - 0.019 14.7 0.5 0.042 13.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF Tir_receptor_C PF07489.6 CCC67350.1 - 0.039 13.7 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus MAT1 PF06391.8 CCC67351.1 - 6.5e-59 198.8 28.8 8e-59 198.5 19.9 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 CCC67351.1 - 0.0041 16.7 5.5 0.024 14.2 4.0 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC67351.1 - 0.02 14.8 7.2 0.055 13.5 5.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCC67351.1 - 0.026 14.1 6.5 0.086 12.5 4.6 1.7 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCC67351.1 - 0.045 13.5 5.9 0.11 12.3 4.0 1.7 1 1 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 CCC67351.1 - 0.12 12.1 8.6 1.2 8.9 6.3 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 CCC67351.1 - 0.27 10.9 5.5 0.64 9.7 2.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 CCC67351.1 - 5.6 6.6 10.1 42 3.8 7.0 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain TRAPP PF04051.11 CCC67352.1 - 2.4e-42 144.0 0.0 3e-42 143.6 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Phage_Treg PF04761.7 CCC67352.1 - 0.13 12.0 0.1 0.38 10.5 0.1 1.8 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator Ribosomal_L27e PF01777.13 CCC67353.1 - 2.7e-36 123.5 7.3 3.8e-36 123.0 5.0 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CCC67353.1 - 0.00017 21.1 1.2 0.00038 20.0 0.8 1.6 1 0 0 1 1 1 1 KOW motif Ndr PF03096.9 CCC67353.1 - 0.04 12.3 0.0 0.077 11.4 0.0 1.4 1 0 0 1 1 1 0 Ndr family Mito_carr PF00153.22 CCC67354.1 - 2.2e-11 43.2 0.0 0.0043 16.7 0.0 4.2 4 0 0 4 4 4 3 Mitochondrial carrier protein Dpy-30 PF05186.8 CCC67355.1 - 4.6e-15 54.8 0.0 6e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif SNARE PF05739.14 CCC67356.1 - 1.8e-13 49.9 6.4 1.8e-13 49.9 4.5 3.1 4 0 0 4 4 3 1 SNARE domain Syntaxin-6_N PF09177.6 CCC67356.1 - 0.00028 21.2 6.0 0.00028 21.2 4.2 2.8 2 1 0 2 2 2 1 Syntaxin 6, N-terminal RmuC PF02646.11 CCC67356.1 - 0.01 14.7 10.1 0.04 12.7 0.7 2.3 2 1 0 2 2 2 0 RmuC family PilJ PF13675.1 CCC67356.1 - 0.014 15.6 3.0 0.41 10.9 0.0 2.2 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2408 PF10303.4 CCC67356.1 - 0.017 15.2 10.2 0.065 13.3 4.6 2.9 2 1 0 3 3 2 0 Protein of unknown function (DUF2408) Sec20 PF03908.8 CCC67356.1 - 0.04 13.6 6.1 0.059 13.0 0.1 2.4 2 1 0 2 2 2 0 Sec20 Use1 PF09753.4 CCC67356.1 - 0.048 13.0 5.8 0.11 11.8 4.0 1.7 1 1 0 1 1 1 0 Membrane fusion protein Use1 DUF3584 PF12128.3 CCC67356.1 - 0.056 10.7 10.5 0.11 9.7 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3209 PF11483.3 CCC67356.1 - 0.09 13.1 5.1 0.12 12.7 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3209) ALMT PF11744.3 CCC67356.1 - 0.094 11.3 5.1 0.24 10.0 3.5 1.7 1 1 0 1 1 1 0 Aluminium activated malate transporter Nup88 PF10168.4 CCC67356.1 - 0.11 10.2 8.3 0.052 11.3 0.4 2.0 2 0 0 2 2 2 0 Nuclear pore component COG2 PF06148.6 CCC67356.1 - 0.14 11.9 6.2 1.2 8.9 1.2 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Vps53_N PF04100.7 CCC67356.1 - 0.26 10.0 9.8 0.05 12.3 4.2 1.6 2 0 0 2 2 2 0 Vps53-like, N-terminal Katanin_con80 PF13925.1 CCC67356.1 - 0.26 11.0 4.0 1.7 8.3 0.3 2.6 2 2 0 2 2 2 0 con80 domain of Katanin GP41 PF00517.12 CCC67356.1 - 0.27 10.7 6.2 1.2 8.6 0.2 2.7 2 1 0 2 2 2 0 Retroviral envelope protein DUF892 PF05974.7 CCC67356.1 - 0.3 10.8 0.2 0.3 10.8 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF892) WXG100 PF06013.7 CCC67356.1 - 0.32 11.0 8.3 7.3 6.6 0.7 3.5 2 2 0 2 2 2 0 Proteins of 100 residues with WXG DUF4208 PF13907.1 CCC67356.1 - 0.33 11.1 7.1 1.6 8.9 1.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4208) AAA_13 PF13166.1 CCC67356.1 - 0.51 8.7 11.3 0.94 7.8 7.9 1.5 1 1 0 1 1 1 0 AAA domain XH PF03469.9 CCC67356.1 - 0.54 9.9 6.1 0.18 11.4 2.0 1.9 2 1 0 2 2 2 0 XH domain DUF1542 PF07564.6 CCC67356.1 - 0.64 10.0 6.6 0.31 11.0 1.7 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Baculo_PEP_C PF04513.7 CCC67356.1 - 0.66 9.7 12.9 2.7 7.8 0.5 3.0 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus MCPsignal PF00015.16 CCC67356.1 - 0.67 9.4 6.0 0.42 10.1 1.8 2.0 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain PEP-utilisers_N PF05524.8 CCC67356.1 - 0.71 9.6 4.2 28 4.5 0.3 3.0 2 1 0 3 3 3 0 PEP-utilising enzyme, N-terminal Mnd1 PF03962.10 CCC67356.1 - 0.89 9.1 9.2 0.12 12.0 1.3 2.2 2 0 0 2 2 2 0 Mnd1 family DUF3450 PF11932.3 CCC67356.1 - 0.95 8.6 8.2 1.1 8.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2203 PF09969.4 CCC67356.1 - 1.4 9.1 6.9 1.4 9.1 1.2 2.3 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Flagellin_N PF00669.15 CCC67356.1 - 1.7 8.4 7.6 4.9 6.9 0.9 2.4 2 1 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4140 PF13600.1 CCC67356.1 - 1.8 9.0 5.3 1.2 9.6 0.9 2.4 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Bacillus_HBL PF05791.6 CCC67356.1 - 1.9 7.8 10.8 0.54 9.6 1.3 2.9 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Sulfatase_C PF14707.1 CCC67356.1 - 1.9 8.7 4.6 5.8 7.2 0.5 2.5 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase V_ATPase_I PF01496.14 CCC67356.1 - 2.1 6.0 11.0 0.15 9.8 3.3 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Phage_GP20 PF06810.6 CCC67356.1 - 2.5 7.5 17.9 1.2 8.6 10.0 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 Microtub_assoc PF07989.6 CCC67356.1 - 2.6 7.9 11.5 1.8 8.4 0.3 3.3 2 1 1 3 3 3 0 Microtubule associated NYD-SP28 PF14772.1 CCC67356.1 - 2.8 8.0 10.6 2 8.5 0.8 3.0 3 0 0 3 3 3 0 Sperm tail T4SS PF07996.6 CCC67356.1 - 3 7.6 10.8 6.8 6.4 5.6 2.5 2 1 0 2 2 2 0 Type IV secretion system proteins Ibs_toxin PF13956.1 CCC67356.1 - 3 7.7 11.1 4.8 7.0 7.7 1.3 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Cob_adeno_trans PF01923.13 CCC67356.1 - 3.5 7.3 6.7 0.92 9.2 1.7 2.1 2 1 0 2 2 2 0 Cobalamin adenosyltransferase DUF724 PF05266.9 CCC67356.1 - 3.9 7.0 12.7 4.1 6.9 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) DUF745 PF05335.8 CCC67356.1 - 4.2 6.8 10.8 1.9 7.9 0.8 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF745) Corona_S2 PF01601.11 CCC67356.1 - 4.2 5.3 7.7 0.68 7.9 0.7 2.3 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein TPR_MLP1_2 PF07926.7 CCC67356.1 - 4.8 6.9 13.5 5.6 6.7 0.6 2.7 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Noelin-1 PF12308.3 CCC67356.1 - 5.7 6.8 10.4 11 5.8 0.7 2.4 2 1 0 2 2 2 0 Neurogenesis glycoprotein DUF342 PF03961.8 CCC67356.1 - 8 4.7 11.3 1.3 7.3 3.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Spc7 PF08317.6 CCC67356.1 - 8.8 4.8 16.1 2.1 6.8 5.8 2.1 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.1 CCC67356.1 - 9.1 5.1 8.1 18 4.2 5.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.17 CCC67356.1 - 9.3 6.3 12.8 16 5.5 5.3 2.7 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.20 CCC67357.1 - 3.7e-65 219.6 0.1 6.1e-65 218.9 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67357.1 - 1.6e-34 119.1 0.0 2.6e-34 118.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC67357.1 - 1.2e-09 37.5 0.0 2.2e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCC67357.1 - 0.0018 18.0 0.0 0.0085 15.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCC67357.1 - 0.0034 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCC67357.1 - 0.047 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Cellulase PF00150.13 CCC67358.1 - 4.3e-12 45.8 8.8 8.6e-12 44.8 6.1 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Apc13p PF05839.6 CCC67359.1 - 1.1e-07 31.7 0.9 1.6e-07 31.1 0.6 1.2 1 0 0 1 1 1 1 Apc13p protein bZIP_1 PF00170.16 CCC67360.1 - 3.2e-08 33.3 9.7 6e-08 32.5 6.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor TPR_MLP1_2 PF07926.7 CCC67360.1 - 0.058 13.1 5.0 0.12 12.1 3.4 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ELL PF10390.4 CCC67360.1 - 0.16 11.1 10.5 0.22 10.6 7.3 1.3 1 1 0 1 1 1 0 RNA polymerase II elongation factor ELL SH3BGR PF04908.10 CCC67360.1 - 0.26 11.2 1.7 1.1 9.2 0.2 2.4 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein Presenilin PF01080.12 CCC67360.1 - 0.39 9.4 7.1 0.084 11.6 2.7 1.5 2 0 0 2 2 2 0 Presenilin TFIIA PF03153.8 CCC67360.1 - 1.6 8.5 16.2 2 8.1 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Adeno_PIX PF03955.9 CCC67360.1 - 3.4 8.2 5.9 0.96 10.0 1.3 2.2 2 1 1 3 3 3 0 Adenovirus hexon-associated protein (IX) bZIP_1 PF00170.16 CCC67361.1 - 1.4e-08 34.5 10.1 3e-08 33.4 7.0 1.6 1 0 0 1 1 1 1 bZIP transcription factor HALZ PF02183.13 CCC67361.1 - 0.0014 18.2 2.2 0.0025 17.5 1.5 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper ORC6 PF05460.8 CCC67361.1 - 0.0074 15.4 4.0 0.01 14.9 2.7 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) CENP-B_dimeris PF09026.5 CCC67361.1 - 0.017 15.3 5.0 0.017 15.3 3.5 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain bZIP_Maf PF03131.12 CCC67361.1 - 0.019 15.2 6.9 0.059 13.6 4.8 1.8 1 0 0 1 1 1 0 bZIP Maf transcription factor PBP1_TM PF14812.1 CCC67361.1 - 0.019 15.2 8.8 0.019 15.2 6.1 3.0 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3708 PF12501.3 CCC67361.1 - 0.24 11.2 4.8 0.19 11.5 2.3 1.6 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter Nucleoplasmin PF03066.10 CCC67361.1 - 0.33 10.4 10.6 0.43 10.0 6.3 1.8 2 0 0 2 2 2 0 Nucleoplasmin Pox_RNA_Pol_19 PF05320.7 CCC67361.1 - 3 7.5 15.3 4.8 6.8 2.4 2.3 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Adeno_PIX PF03955.9 CCC67361.1 - 5.3 7.6 10.5 1.5 9.3 1.3 2.3 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Shadoo PF14999.1 CCC67361.1 - 8.9 6.1 14.2 3.1 7.6 5.1 2.1 1 1 1 2 2 2 0 Shadow of prion protein, neuroprotective AAA_2 PF07724.9 CCC67362.1 - 5.2e-51 172.9 0.1 3.1e-48 163.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 CCC67362.1 - 3.6e-25 87.6 0.2 1.2e-24 85.9 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 CCC67362.1 - 6e-22 78.2 0.1 2.6e-11 43.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCC67362.1 - 1.6e-15 57.0 0.2 7.9e-11 41.8 0.0 3.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCC67362.1 - 9.2e-15 55.1 3.5 0.00026 21.0 0.0 4.6 3 2 1 5 5 4 3 AAA ATPase domain AAA_22 PF13401.1 CCC67362.1 - 1.3e-09 38.3 0.0 0.00086 19.4 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CCC67362.1 - 4.9e-08 32.9 0.0 0.012 15.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CCC67362.1 - 1.4e-07 31.4 6.2 0.00084 19.0 0.3 4.5 3 2 1 4 4 4 1 Archaeal ATPase Sigma54_activat PF00158.21 CCC67362.1 - 4.7e-07 29.4 0.1 2.7e-05 23.7 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_17 PF13207.1 CCC67362.1 - 5.8e-07 30.3 3.7 0.015 16.0 0.0 3.8 2 1 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CCC67362.1 - 1.2e-06 28.1 0.0 0.047 13.1 0.0 3.3 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_18 PF13238.1 CCC67362.1 - 2.8e-05 24.4 5.4 0.065 13.5 0.1 3.4 4 0 0 4 4 2 2 AAA domain ABC_tran PF00005.22 CCC67362.1 - 5.2e-05 23.5 0.5 0.097 12.9 0.0 3.1 3 0 0 3 3 3 1 ABC transporter Zeta_toxin PF06414.7 CCC67362.1 - 6.3e-05 22.1 0.0 0.0025 16.9 0.0 3.1 2 1 0 2 2 2 1 Zeta toxin NACHT PF05729.7 CCC67362.1 - 0.00012 21.7 0.0 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 CCC67362.1 - 0.00017 21.5 0.0 0.44 10.4 0.0 3.3 3 0 0 3 3 2 1 AAA domain DUF258 PF03193.11 CCC67362.1 - 0.0002 20.5 0.0 0.036 13.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CCC67362.1 - 0.00034 20.5 0.1 0.055 13.4 0.0 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase MobB PF03205.9 CCC67362.1 - 0.00036 20.2 0.0 0.37 10.5 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CCC67362.1 - 0.00045 19.6 0.0 0.091 12.3 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_19 PF13245.1 CCC67362.1 - 0.0007 19.3 0.0 1.7 8.4 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain PduV-EutP PF10662.4 CCC67362.1 - 0.00086 18.8 0.0 0.47 9.9 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 CCC67362.1 - 0.00093 19.3 0.0 1.5 9.0 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.1 CCC67362.1 - 0.0014 18.2 0.0 1 8.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 CCC67362.1 - 0.0022 16.9 1.2 0.48 9.3 0.2 3.3 3 2 0 3 3 3 1 Protein of unknown function (DUF815) T2SE PF00437.15 CCC67362.1 - 0.0022 16.9 0.3 0.031 13.1 0.1 2.6 2 1 0 2 2 2 1 Type II/IV secretion system protein UPF0079 PF02367.12 CCC67362.1 - 0.0038 16.8 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 CCC67362.1 - 0.0096 14.5 0.0 1.1 7.7 0.0 2.5 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain SRP54 PF00448.17 CCC67362.1 - 0.011 15.1 0.0 1.6 8.1 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 CCC67362.1 - 0.013 14.7 0.0 1.3 8.1 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CCC67362.1 - 0.017 14.6 0.0 6.1 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_6 PF12774.2 CCC67362.1 - 0.022 14.2 0.2 6.3 6.2 0.1 2.4 2 0 0 2 2 2 0 Hydrolytic ATP binding site of dynein motor region D1 AAA_3 PF07726.6 CCC67362.1 - 0.022 14.3 0.1 0.56 9.8 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Torsin PF06309.6 CCC67362.1 - 0.024 14.5 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Torsin AAA_25 PF13481.1 CCC67362.1 - 0.027 13.8 2.5 6.7 6.0 0.0 3.4 3 2 0 3 3 3 0 AAA domain Miro PF08477.8 CCC67362.1 - 0.028 14.9 0.0 0.61 10.5 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_33 PF13671.1 CCC67362.1 - 0.033 14.0 0.2 4.2 7.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain ResIII PF04851.10 CCC67362.1 - 0.037 13.8 0.3 7.4 6.3 0.0 3.5 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit PhoH PF02562.11 CCC67362.1 - 0.037 13.2 0.0 2.9 7.0 0.0 2.7 2 0 0 2 2 2 0 PhoH-like protein ATP_bind_1 PF03029.12 CCC67362.1 - 0.052 13.0 0.0 6.8 6.1 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CCC67362.1 - 0.058 12.8 0.3 2.7 7.3 0.0 3.2 2 2 2 4 4 4 0 AAA-like domain DUF1090 PF06476.7 CCC67362.1 - 0.2 11.3 8.8 0.56 9.8 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) SET PF00856.23 CCC67363.1 - 8.1e-12 45.7 0.0 1.7e-11 44.6 0.0 1.6 1 1 0 1 1 1 1 SET domain Pex24p PF06398.6 CCC67364.1 - 1.2e-80 271.0 8.7 2e-80 270.3 6.1 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Rpr2 PF04032.11 CCC67365.1 - 1.4e-11 44.1 0.2 1.4e-11 44.1 0.1 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zinc_ribbon_2 PF13240.1 CCC67365.1 - 0.024 14.1 5.3 0.62 9.6 1.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 CCC67365.1 - 0.3 10.3 6.2 2.4 7.4 1.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 CCC67365.1 - 0.33 10.6 3.6 10 5.8 0.2 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) DNA_RNApol_7kD PF03604.8 CCC67365.1 - 2.4 7.7 5.5 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Pkinase PF00069.20 CCC67366.1 - 6.1e-78 261.5 0.1 9.2e-78 260.9 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67366.1 - 2.4e-39 134.9 0.0 3.5e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 CCC67366.1 - 4.9e-21 74.6 2.2 6.4e-21 74.2 0.7 1.9 2 0 0 2 2 2 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 CCC67366.1 - 1.6e-10 40.4 0.0 3.2e-10 39.4 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 CCC67366.1 - 2.8e-06 26.8 1.0 5.2e-06 25.9 0.7 1.3 1 0 0 1 1 1 1 RIO1 family YukC PF10140.4 CCC67366.1 - 0.0002 20.0 0.2 0.00034 19.2 0.2 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.9 CCC67366.1 - 0.0051 15.9 0.1 0.0084 15.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC67366.1 - 0.024 14.3 0.1 0.71 9.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Zip PF02535.17 CCC67366.1 - 2.4 7.0 8.2 4.8 6.0 5.7 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Usp PF00582.21 CCC67368.1 - 0.051 13.7 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 Universal stress protein family PRP3 PF08572.5 CCC67369.1 - 5e-57 192.8 18.8 9.2e-57 191.9 13.0 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 CCC67369.1 - 7e-33 113.0 0.3 7e-33 113.0 0.2 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF1115) Glyco_hydro_20b PF02838.10 CCC67369.1 - 0.071 13.6 0.9 0.46 11.0 0.0 2.5 2 1 0 2 2 2 0 Glycosyl hydrolase family 20, domain 2 RNA_Me_trans PF04252.8 CCC67370.1 - 8.1e-80 266.8 0.0 9e-80 266.7 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase DUF3020 PF11223.3 CCC67371.1 - 1.1e-11 44.9 4.1 1.1e-11 44.9 2.9 9.0 8 0 0 8 8 8 1 Protein of unknown function (DUF3020) UIM PF02809.15 CCC67371.1 - 1.3 8.7 4.8 1.2 8.9 0.0 3.5 4 0 0 4 4 4 0 Ubiquitin interaction motif Methyltransf_4 PF02390.12 CCC67372.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_11 PF08241.7 CCC67372.1 - 0.032 14.7 0.0 0.06 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ArgJ PF01960.13 CCC67373.1 - 2.6e-142 473.8 9.2 3e-142 473.6 6.4 1.0 1 0 0 1 1 1 1 ArgJ family Suf PF05843.9 CCC67374.1 - 1e-71 241.9 13.3 1e-71 241.9 9.2 3.8 2 2 0 2 2 2 1 Suppressor of forked protein (Suf) DUF842 PF05811.8 CCC67374.1 - 0.0038 16.6 2.1 0.011 15.2 1.5 1.7 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Tom37_C PF11801.3 CCC67375.1 - 4.8e-40 137.1 0.6 7.3e-40 136.5 0.4 1.3 1 0 0 1 1 1 1 Tom37 C-terminal domain Tom37 PF10568.4 CCC67375.1 - 5.7e-17 61.7 0.1 1e-16 60.9 0.0 1.4 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein DUF4448 PF14610.1 CCC67376.1 - 1.5e-46 158.2 1.0 2.3e-46 157.6 0.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF3492 PF11997.3 CCC67377.1 - 1.9 7.9 4.6 1.1 8.6 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3492) Cu-oxidase_2 PF07731.9 CCC67378.1 - 9.5e-44 148.2 5.1 5.6e-40 136.0 1.1 3.4 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 CCC67378.1 - 1.5e-41 140.7 9.4 1.4e-39 134.4 0.4 3.5 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 CCC67378.1 - 3.8e-33 114.6 8.3 4e-31 108.0 1.8 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cupredoxin_1 PF13473.1 CCC67378.1 - 0.032 14.1 0.0 0.4 10.5 0.0 2.8 4 0 0 4 4 4 0 Cupredoxin-like domain Mito_carr PF00153.22 CCC67379.1 - 2.2e-69 229.2 3.9 2.4e-24 84.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RabGAP-TBC PF00566.13 CCC67380.1 - 1.4e-32 112.9 0.4 3.5e-32 111.6 0.3 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain JTB PF05439.7 CCC67380.1 - 0.036 13.8 0.0 0.07 12.9 0.0 1.4 1 0 0 1 1 1 0 Jumping translocation breakpoint protein (JTB) V_ATPase_I PF01496.14 CCC67381.1 - 2.6e-282 938.2 5.7 3e-282 938.0 3.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family FliD_C PF07195.7 CCC67381.1 - 0.0045 16.3 1.9 0.29 10.4 0.1 2.6 2 0 0 2 2 2 2 Flagellar hook-associated protein 2 C-terminus Baculo_PEP_C PF04513.7 CCC67381.1 - 0.0066 16.2 7.5 0.68 9.7 1.3 2.7 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.1 CCC67381.1 - 0.031 13.6 5.6 0.86 8.8 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Matrilin_ccoil PF10393.4 CCC67381.1 - 0.054 12.8 3.0 0.041 13.2 0.5 2.1 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF972 PF06156.8 CCC67381.1 - 2.3 8.6 5.2 4.2 7.7 0.0 3.1 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 CCC67381.1 - 2.8 8.0 6.9 7.6 6.6 0.2 3.2 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Cob_adeno_trans PF01923.13 CCC67382.1 - 0.07 12.9 1.1 0.19 11.5 0.7 1.8 1 1 0 1 1 1 0 Cobalamin adenosyltransferase LEA_4 PF02987.11 CCC67382.1 - 0.16 11.8 0.7 0.32 10.8 0.5 1.5 1 0 0 1 1 1 0 Late embryogenesis abundant protein Vps55 PF04133.9 CCC67383.1 - 1.7e-43 147.1 6.2 2e-43 146.9 4.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DUF2085 PF09858.4 CCC67383.1 - 0.066 13.2 0.5 0.12 12.4 0.1 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2085) DUF998 PF06197.8 CCC67383.1 - 0.28 10.4 6.3 0.3 10.3 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF998) DUF1049 PF06305.6 CCC67383.1 - 0.41 10.1 3.0 1.3 8.5 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF4018 PF13210.1 CCC67383.1 - 3.8 6.8 10.7 0.19 11.0 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4018) HSP70 PF00012.15 CCC67384.1 - 1.1e-267 888.9 14.8 1.2e-267 888.7 10.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCC67384.1 - 2.3e-15 56.0 2.9 4.3e-13 48.5 0.5 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CCC67384.1 - 0.0013 18.3 0.0 0.0032 17.0 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Gp-FAR-1 PF05823.7 CCC67384.1 - 0.042 13.7 8.0 0.092 12.7 5.5 1.5 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) FtsA PF14450.1 CCC67384.1 - 0.046 13.5 12.9 1.9 8.3 1.7 4.7 4 1 0 4 4 4 0 Cell division protein FtsA Hydantoinase_A PF01968.13 CCC67384.1 - 0.053 12.6 7.1 0.21 10.6 0.1 3.3 2 1 0 3 3 3 0 Hydantoinase/oxoprolinase DUF2797 PF10977.3 CCC67384.1 - 0.055 13.0 2.9 0.11 12.0 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) DnaG_DnaB_bind PF08278.6 CCC67384.1 - 0.95 9.6 5.4 2.2 8.5 3.7 1.6 1 0 0 1 1 1 0 DNA primase DnaG DnaB-binding Bap31 PF05529.7 CCC67384.1 - 1.8 7.9 8.0 3.6 6.9 5.5 1.5 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like CDT1 PF08839.6 CCC67385.1 - 0.00062 19.7 0.2 0.0039 17.1 0.2 2.3 2 1 0 2 2 2 1 DNA replication factor CDT1 like zf-RING_2 PF13639.1 CCC67386.1 - 6e-12 45.1 11.1 1.1e-11 44.3 7.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCC67386.1 - 9.2e-09 35.3 9.5 2.6e-08 33.8 6.6 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCC67386.1 - 1e-05 25.2 6.1 2.3e-05 24.1 4.2 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CCC67386.1 - 1.1e-05 24.9 11.4 1.1e-05 24.9 7.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC67386.1 - 0.00078 19.4 14.4 0.0009 19.2 9.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC67386.1 - 0.0019 17.8 8.9 0.0019 17.8 6.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCC67386.1 - 0.003 17.1 9.7 0.003 17.1 6.8 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 CCC67386.1 - 0.017 15.1 8.1 0.017 15.1 5.6 2.9 2 2 0 2 2 2 0 FANCL C-terminal domain zf-Nse PF11789.3 CCC67386.1 - 0.03 13.8 10.3 0.028 13.9 6.1 1.7 1 1 1 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF2674 PF10879.3 CCC67386.1 - 0.13 12.0 0.1 0.5 10.1 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2674) zf-Di19 PF05605.7 CCC67386.1 - 2 8.6 0.0 2 8.6 0.0 2.8 3 1 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_4 PF15227.1 CCC67386.1 - 3.4 7.6 12.5 14 5.6 8.7 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-P11 PF03854.9 CCC67386.1 - 8.9 5.8 15.2 12 5.4 7.1 2.4 1 1 1 2 2 2 0 P-11 zinc finger Nucleoporin_FG PF13634.1 CCC67387.1 - 5.9e-60 200.5 307.9 5.1e-12 46.0 31.4 9.0 2 1 7 9 9 9 9 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 CCC67387.1 - 8.4e-37 126.1 0.0 1.9e-36 125.0 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin autopeptidase Swi3 PF07962.7 CCC67388.1 - 9.3e-30 102.1 0.3 1.7e-29 101.2 0.2 1.4 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 IBB PF01749.15 CCC67388.1 - 2.1 8.5 6.4 12 6.1 0.8 2.8 1 1 1 2 2 2 0 Importin beta binding domain CDC27 PF09507.5 CCC67389.1 - 2.1e-06 27.2 31.7 2.1e-06 27.2 22.0 1.8 2 0 0 2 2 2 1 DNA polymerase subunit Cdc27 TEX19 PF15553.1 CCC67389.1 - 5.9 6.7 13.4 0.12 12.2 2.8 2.6 3 0 0 3 3 3 0 Testis-expressed protein 19 ATP-synt_C PF00137.16 CCC67390.1 - 9.8e-32 108.6 28.4 1.3e-18 66.6 7.0 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Urb2 PF10441.4 CCC67391.1 - 4e-56 190.1 3.4 4e-56 190.1 2.4 2.7 3 0 0 3 3 3 1 Urb2/Npa2 family Voltage_CLC PF00654.15 CCC67392.1 - 2.2e-80 270.3 22.6 2.2e-80 270.3 15.6 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 CCC67392.1 - 2e-12 46.6 0.0 3.9e-07 29.7 0.0 2.4 2 0 0 2 2 2 2 CBS domain Herpes_UL45 PF05473.7 CCC67392.1 - 0.18 11.2 0.1 0.18 11.2 0.1 1.8 2 0 0 2 2 2 0 UL45 protein Ribosomal_L7Ae PF01248.21 CCC67393.1 - 1.1e-27 95.3 0.1 1.3e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 CCC67393.1 - 0.01 15.6 0.0 0.011 15.5 0.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 PELOTA_1 PF15608.1 CCC67393.1 - 0.028 14.2 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain HECT PF00632.20 CCC67395.1 - 1e-85 287.7 3.0 1.8e-85 286.8 2.1 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.17 CCC67395.1 - 0.021 14.5 2.7 0.092 12.4 1.9 2.1 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SNF2_N PF00176.18 CCC67396.1 - 2.3e-76 256.4 0.1 4e-76 255.6 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCC67396.1 - 1.4e-13 50.5 0.0 5e-13 48.7 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PHD PF00628.24 CCC67397.1 - 5.6e-09 35.5 9.0 9.2e-09 34.8 6.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CCC67397.1 - 0.013 15.5 1.1 0.013 15.5 0.8 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain Pet191_N PF10203.4 CCC67398.1 - 2.8e-26 91.3 3.5 3.8e-26 90.9 2.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 CCC67398.1 - 0.046 13.5 0.6 5.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4314 PF14192.1 CCC67398.1 - 0.091 13.0 0.0 0.1 12.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4314) CHCH PF06747.8 CCC67398.1 - 0.097 12.6 2.5 1.3 9.0 0.5 2.7 2 1 0 2 2 2 0 CHCH domain Rav1p_C PF12234.3 CCC67399.1 - 1.8e-251 835.8 1.1 1.8e-251 835.8 0.7 1.8 2 0 0 2 2 2 1 RAVE protein 1 C terminal WD40 PF00400.27 CCC67399.1 - 9.3e-08 31.6 14.6 0.033 14.0 0.0 7.5 7 1 0 7 7 7 2 WD domain, G-beta repeat Pro_isomerase PF00160.16 CCC67400.1 - 3.4e-38 131.2 0.1 5.9e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CCC67400.1 - 5e-10 38.8 11.3 7.3e-06 25.5 2.5 2.4 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 CCC67400.1 - 5.7e-10 38.3 12.5 8.5e-06 25.3 0.9 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 CCC67400.1 - 2.4e-09 36.4 14.6 2.8e-07 29.8 2.4 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCC67400.1 - 0.00032 20.5 6.0 0.77 9.7 2.9 3.1 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCC67400.1 - 0.0039 17.8 0.1 0.65 10.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 CCC67400.1 - 0.0053 16.6 4.9 0.12 12.3 0.1 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 CCC67400.1 - 0.012 16.0 0.4 0.012 16.0 0.3 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1771 PF08590.5 CCC67400.1 - 0.12 12.4 0.4 0.23 11.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) TPR_8 PF13181.1 CCC67400.1 - 0.94 9.4 23.3 0.064 13.0 2.5 4.2 3 1 1 4 4 4 0 Tetratricopeptide repeat Sec7 PF01369.15 CCC67401.1 - 1.4e-57 194.4 3.0 4.1e-57 192.9 2.1 1.8 1 0 0 1 1 1 1 Sec7 domain tRNA-synt_2 PF00152.15 CCC67402.1 - 6.5e-70 235.5 0.0 8.6e-70 235.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCC67402.1 - 6.2e-06 25.9 0.0 1.2e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain PMP1_2 PF08114.6 CCC67403.1 - 9.7e-27 92.1 4.7 1e-26 92.1 3.2 1.0 1 0 0 1 1 1 1 ATPase proteolipid family DUF1049 PF06305.6 CCC67403.1 - 0.003 16.9 2.1 0.0037 16.6 1.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) P12 PF12669.2 CCC67403.1 - 0.98 9.6 2.7 1.1 9.5 1.9 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family Phosphodiest PF01663.17 CCC67404.1 - 1.9e-39 136.0 0.6 3.1e-39 135.3 0.4 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Ras PF00071.17 CCC67405.1 - 2.3e-43 147.3 0.2 2.7e-43 147.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 CCC67405.1 - 7.2e-14 51.4 0.2 8.7e-14 51.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CCC67405.1 - 9.4e-12 45.4 0.0 1.4e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CCC67405.1 - 1.1e-07 31.4 1.6 6.2e-06 25.7 1.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCC67405.1 - 6.8e-07 29.2 0.1 1.2e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCC67405.1 - 0.00013 21.2 0.4 0.00017 20.8 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CCC67405.1 - 0.011 15.9 0.4 1.7 8.8 0.1 3.0 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 CCC67405.1 - 0.015 15.0 0.1 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 CCC67405.1 - 0.035 13.8 0.2 0.052 13.2 0.1 1.5 1 1 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 CCC67405.1 - 0.041 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 CCC67405.1 - 0.055 12.7 0.1 0.098 11.9 0.1 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B Baculo_p74 PF04583.7 CCC67405.1 - 0.064 12.4 0.3 0.27 10.4 0.1 1.9 1 1 1 2 2 2 0 Baculoviridae p74 conserved region AAA_28 PF13521.1 CCC67405.1 - 0.086 12.8 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain PfkB PF00294.19 CCC67406.1 - 1.3e-11 44.2 0.0 1e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 pfkB family carbohydrate kinase YjcQ PF09639.5 CCC67406.1 - 0.0021 18.1 0.1 0.0055 16.7 0.0 1.8 2 0 0 2 2 2 1 YjcQ protein TENA_THI-4 PF03070.11 CCC67407.1 - 1.5e-13 50.9 2.4 2.1e-13 50.5 1.7 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family LSM PF01423.17 CCC67408.1 - 3.3e-12 45.7 0.0 4.3e-12 45.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain Adeno_PIX PF03955.9 CCC67409.1 - 0.11 13.0 1.5 0.16 12.4 1.1 1.2 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) Frag1 PF10277.4 CCC67411.1 - 7.8e-36 123.5 13.8 7.8e-36 123.5 9.6 3.5 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Glyco_transf_15 PF01793.11 CCC67412.1 - 1.3e-85 287.2 13.9 1.6e-85 286.9 9.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DNA_pol_B_thumb PF14791.1 CCC67413.1 - 1e-18 66.7 0.1 2.4e-18 65.5 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 CCC67413.1 - 1.7e-16 60.2 0.0 1.4e-14 54.0 0.0 2.9 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.1 CCC67413.1 - 1.6e-13 50.6 0.8 3.5e-13 49.5 0.6 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain BRCT PF00533.21 CCC67413.1 - 9.1e-05 22.5 0.6 0.0014 18.7 0.1 3.1 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain DNA_pol_lambd_f PF10391.4 CCC67413.1 - 0.00031 20.2 0.9 0.0036 16.8 0.0 3.1 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda NTP_transf_2 PF01909.18 CCC67413.1 - 0.035 14.4 0.3 0.18 12.1 0.1 2.3 2 0 0 2 2 2 0 Nucleotidyltransferase domain PGK PF00162.14 CCC67414.1 - 3.4e-153 509.7 0.2 3.9e-153 509.5 0.2 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF1779 PF08680.5 CCC67414.1 - 0.1 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1779) ABC2_membrane PF01061.19 CCC67415.1 - 5.4e-37 127.0 20.3 1e-36 126.0 14.0 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 CCC67415.1 - 1.1e-26 93.7 0.0 1.9e-26 92.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 CCC67415.1 - 5.6e-05 22.6 0.1 0.023 14.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 CCC67415.1 - 0.00015 20.9 3.3 0.12 11.3 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 CCC67415.1 - 0.0015 17.7 0.2 0.0037 16.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCC67415.1 - 0.0075 15.7 0.4 0.025 14.0 0.2 1.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain EGF_2 PF07974.8 CCC67415.1 - 0.012 15.7 5.8 0.012 15.7 4.0 4.3 5 0 0 5 5 4 0 EGF-like domain AAA_16 PF13191.1 CCC67415.1 - 0.017 15.1 0.0 0.045 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 CCC67415.1 - 0.03 14.3 0.9 0.047 13.6 0.2 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CCC67415.1 - 0.077 13.1 0.2 0.19 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CCC67415.1 - 0.083 12.8 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit hEGF PF12661.2 CCC67415.1 - 0.88 9.7 12.7 0.98 9.6 3.3 3.3 2 0 0 2 2 2 0 Human growth factor-like EGF AAA_23 PF13476.1 CCC67415.1 - 1.2 9.4 6.5 4.8 7.4 4.5 2.1 1 1 0 1 1 1 0 AAA domain RNA_pol_Rpc34 PF05158.7 CCC67416.1 - 1.4e-98 330.1 0.7 1.7e-98 329.8 0.5 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit Rrf2 PF02082.15 CCC67416.1 - 0.011 15.7 1.7 0.019 15.0 0.1 2.1 2 0 0 2 2 2 0 Transcriptional regulator B-block_TFIIIC PF04182.7 CCC67416.1 - 0.029 14.2 3.4 0.15 11.9 0.1 2.4 1 1 1 2 2 2 0 B-block binding subunit of TFIIIC SUA5 PF03481.8 CCC67416.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding Grp1_Fun34_YaaH PF01184.14 CCC67417.1 - 1.9e-94 314.8 16.7 2.2e-94 314.6 11.5 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3483 PF11982.3 CCC67417.1 - 2.6 7.2 6.0 1.9 7.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) BAR PF03114.13 CCC67418.1 - 5.5e-52 176.5 1.1 7.3e-52 176.1 0.7 1.2 1 0 0 1 1 1 1 BAR domain DUF1496 PF07383.7 CCC67418.1 - 0.0026 16.9 0.6 0.0054 15.9 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1496) MSV199 PF10553.4 CCC67418.1 - 1.1 9.1 7.8 0.31 10.9 2.7 2.1 2 1 1 3 3 3 0 MSV199 domain Pkinase PF00069.20 CCC67419.1 - 1.1e-63 214.7 0.0 2.2e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67419.1 - 1.3e-27 96.5 0.0 2e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cytadhesin_P30 PF07271.6 CCC67419.1 - 9.3e-05 21.8 2.1 0.00014 21.2 1.4 1.2 1 0 0 1 1 1 1 Cytadhesin P30/P32 Kinase-like PF14531.1 CCC67419.1 - 0.044 12.7 0.0 0.091 11.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 CCC67419.1 - 0.067 12.7 0.2 2.5 7.6 0.0 2.8 3 0 0 3 3 3 0 Choline/ethanolamine kinase Kdo PF06293.9 CCC67419.1 - 0.15 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC67419.1 - 0.17 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DivIC PF04977.10 CCC67420.1 - 7.6 6.0 10.5 4.9 6.7 1.0 3.2 3 0 0 3 3 3 0 Septum formation initiator Sugar_tr PF00083.19 CCC67421.1 - 1.1e-160 535.1 35.9 1.3e-160 534.9 24.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC67421.1 - 5.2e-28 97.7 38.8 1.9e-24 86.0 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCC67421.1 - 0.00099 17.3 4.9 0.00099 17.3 3.4 1.5 2 0 0 2 2 2 1 Transmembrane secretion effector Secretin_N_2 PF07655.8 CCC67421.1 - 0.025 14.9 5.3 0.049 14.0 3.7 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain adh_short PF00106.20 CCC67422.1 - 1.6e-31 109.4 0.1 2.2e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCC67422.1 - 5.2e-17 62.4 0.3 6.1e-17 62.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCC67422.1 - 6.7e-13 48.6 0.0 9.5e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCC67422.1 - 6e-05 22.5 0.4 0.00015 21.2 0.3 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCC67422.1 - 0.007 15.0 0.1 0.012 14.3 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCC67422.1 - 0.036 14.0 0.1 0.057 13.4 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding AlaDh_PNT_N PF05222.10 CCC67423.1 - 2.4e-30 105.3 0.0 3.4e-30 104.8 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 CCC67423.1 - 4.9e-17 61.9 0.0 6.6e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PS_pyruv_trans PF04230.8 CCC67423.1 - 0.008 15.9 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide pyruvyl transferase DUF1900 PF08954.6 CCC67423.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) Ank PF00023.25 CCC67424.1 - 3.1e-15 55.1 0.1 1.4e-08 34.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 CCC67424.1 - 1.4e-12 47.7 0.1 3.3e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CCC67424.1 - 6.1e-11 41.4 0.1 1.8e-06 27.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CCC67424.1 - 8.9e-11 42.0 0.1 2.2e-05 24.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) TIG PF01833.19 CCC67424.1 - 2.3e-10 40.3 0.6 1.7e-09 37.5 0.0 2.8 2 0 0 2 2 2 1 IPT/TIG domain Ank_5 PF13857.1 CCC67424.1 - 6.4e-08 32.5 0.1 0.00012 22.2 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) MutS_V PF00488.16 CCC67425.1 - 1.4e-97 325.7 0.0 2.3e-97 325.0 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCC67425.1 - 1.4e-33 116.4 1.7 1.4e-33 116.4 1.2 2.9 3 1 0 3 3 3 1 MutS domain III MutS_II PF05188.12 CCC67425.1 - 3.1e-20 72.6 0.3 3.1e-20 72.6 0.2 2.8 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 CCC67425.1 - 2.4e-18 66.0 1.2 2.4e-18 66.0 0.8 2.5 2 0 0 2 2 2 1 MutS family domain IV MutS_I PF01624.15 CCC67425.1 - 1.9e-12 47.2 0.2 1.1e-11 44.6 0.0 2.3 3 0 0 3 3 3 1 MutS domain I Seryl_tRNA_N PF02403.17 CCC67426.1 - 3.7 7.6 33.7 0.027 14.4 5.7 3.8 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 CCC67426.1 - 9.2 5.2 31.9 0.41 9.6 16.8 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 Spc7 PF08317.6 CCC67426.1 - 9.6 4.7 37.7 4.1 5.9 18.4 2.6 1 1 2 3 3 3 0 Spc7 kinetochore protein PQ-loop PF04193.9 CCC67427.1 - 6.6e-19 67.2 3.5 6.6e-19 67.2 2.4 2.1 2 0 0 2 2 2 1 PQ loop repeat Steroid_dh PF02544.11 CCC67427.1 - 0.054 13.2 0.6 0.12 12.1 0.4 1.7 1 1 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase tRNA_m1G_MT PF01746.16 CCC67428.1 - 6.5e-41 139.9 0.1 1.2e-40 139.0 0.1 1.5 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase Rep_fac_C PF08542.6 CCC67429.1 - 8.4e-18 64.1 0.3 4.5e-17 61.7 0.0 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CCC67429.1 - 2.5e-13 50.0 0.1 3.9e-11 42.8 0.1 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CCC67429.1 - 6.2e-13 49.0 0.0 1.2e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 CCC67429.1 - 1.7e-07 31.2 0.0 2.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC67429.1 - 3.5e-06 27.1 0.1 8.5e-05 22.6 0.0 2.4 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 CCC67429.1 - 3.9e-06 25.8 0.0 0.014 14.1 0.0 2.2 1 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CCC67429.1 - 4.8e-06 26.7 0.4 0.11 12.6 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_3 PF07726.6 CCC67429.1 - 5.3e-05 22.8 0.0 9.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCC67429.1 - 0.00013 21.1 0.1 0.0006 18.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 CCC67429.1 - 0.00016 21.2 0.0 0.00029 20.4 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.8 CCC67429.1 - 0.00027 20.5 0.4 0.00042 19.8 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_10 PF12846.2 CCC67429.1 - 0.00052 19.5 0.0 0.07 12.5 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain AAA_19 PF13245.1 CCC67429.1 - 0.0067 16.1 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 CCC67429.1 - 0.0087 15.2 0.0 0.11 11.6 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 CCC67429.1 - 0.013 14.9 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 CCC67429.1 - 0.028 14.1 0.1 0.37 10.4 0.1 2.3 1 1 1 2 2 2 0 NTPase AAA_31 PF13614.1 CCC67429.1 - 0.03 14.2 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CCC67429.1 - 0.036 13.4 0.1 0.1 11.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CCC67429.1 - 0.039 13.5 0.0 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 CCC67429.1 - 0.044 12.5 0.1 0.39 9.4 0.0 2.3 2 1 1 3 3 3 0 ArgK protein KTI12 PF08433.5 CCC67429.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF2075 PF09848.4 CCC67429.1 - 0.08 11.8 0.1 0.45 9.4 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Iso_dh PF00180.15 CCC67430.1 - 2e-74 250.6 0.1 2.4e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Glyco_hydro_76 PF03663.9 CCC67431.1 - 4.9e-143 476.9 17.3 4.9e-143 476.9 12.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 76 Glyco_hydro_76 PF03663.9 CCC67432.1 - 5e-138 460.5 10.3 6.3e-138 460.1 7.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 EF-hand_6 PF13405.1 CCC67433.1 - 0.00012 21.6 1.1 0.53 10.3 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 CCC67433.1 - 0.0006 19.3 0.9 0.0006 19.3 0.6 2.3 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_7 PF13499.1 CCC67433.1 - 0.011 15.8 0.6 0.011 15.8 0.4 2.1 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 CCC67433.1 - 0.02 14.1 0.7 0.02 14.1 0.5 2.1 2 0 0 2 2 2 0 EF hand ABC_tran PF00005.22 CCC67434.1 - 3.1e-44 150.5 0.1 5.3e-22 78.6 0.0 4.5 3 2 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CCC67434.1 - 4.1e-17 63.0 0.1 0.006 16.5 0.0 4.8 4 1 0 5 5 4 4 AAA domain SMC_N PF02463.14 CCC67434.1 - 3.7e-15 55.7 0.0 6.3e-07 28.8 0.0 3.8 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCC67434.1 - 3.1e-09 36.2 0.0 0.002 17.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CCC67434.1 - 5.2e-09 36.3 0.1 0.00076 19.6 0.0 4.1 5 1 0 5 5 3 2 AAA domain AAA_17 PF13207.1 CCC67434.1 - 1.4e-08 35.6 0.0 0.0038 18.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 CCC67434.1 - 2.1e-08 33.5 0.1 0.00012 21.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 CCC67434.1 - 4.4e-08 33.6 6.5 0.0019 18.5 0.0 3.5 4 0 0 4 4 3 2 AAA domain Dynamin_N PF00350.18 CCC67434.1 - 2.7e-07 30.5 0.0 4.8e-05 23.2 0.0 2.8 2 0 0 2 2 2 1 Dynamin family AAA_28 PF13521.1 CCC67434.1 - 7e-07 29.3 0.1 0.0065 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CCC67434.1 - 8.7e-07 28.9 0.0 0.0057 16.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 CCC67434.1 - 1.2e-06 28.2 0.1 0.17 11.2 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain Miro PF08477.8 CCC67434.1 - 1.9e-06 28.3 0.0 0.029 14.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA PF00004.24 CCC67434.1 - 2.6e-06 27.6 0.9 0.99 9.6 0.0 4.4 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CCC67434.1 - 5.4e-06 26.3 0.0 0.086 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCC67434.1 - 6.7e-06 26.4 0.1 0.024 14.9 0.0 3.6 3 0 0 3 3 2 1 AAA domain SbcCD_C PF13558.1 CCC67434.1 - 6.9e-06 25.9 0.0 0.02 14.7 0.0 3.3 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CCC67434.1 - 1e-05 25.6 0.0 0.1 12.7 0.0 3.0 3 0 0 3 3 2 2 RNA helicase MobB PF03205.9 CCC67434.1 - 2.1e-05 24.2 0.0 0.38 10.4 0.0 3.1 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 CCC67434.1 - 3.8e-05 22.6 0.1 0.2 10.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein MMS19_C PF12460.3 CCC67434.1 - 7.5e-05 21.6 0.7 0.099 11.3 0.0 3.2 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal Arch_ATPase PF01637.13 CCC67434.1 - 8.8e-05 22.3 0.0 0.47 10.1 0.0 3.4 2 0 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 CCC67434.1 - 0.00012 22.1 6.0 0.16 11.9 0.1 4.7 4 1 0 4 4 4 1 AAA ATPase domain HEAT_2 PF13646.1 CCC67434.1 - 0.00014 22.0 6.6 0.0061 16.8 0.1 3.7 2 1 2 4 4 3 2 HEAT repeats MutS_V PF00488.16 CCC67434.1 - 0.00014 21.3 0.0 0.15 11.4 0.0 2.4 2 0 0 2 2 2 2 MutS domain V AAA_14 PF13173.1 CCC67434.1 - 0.00065 19.6 0.0 2.9 7.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain ParcG PF10274.4 CCC67434.1 - 0.00073 19.4 0.7 0.32 10.8 0.1 3.1 2 1 1 3 3 3 1 Parkin co-regulated protein UME PF08064.8 CCC67434.1 - 0.00094 19.1 1.3 0.0047 16.8 0.3 2.4 1 1 1 2 2 2 1 UME (NUC010) domain AAA_30 PF13604.1 CCC67434.1 - 0.0011 18.6 0.2 1.8 8.0 0.0 3.5 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 CCC67434.1 - 0.0011 18.5 0.0 0.71 9.5 0.0 2.7 2 0 0 2 2 2 1 NACHT domain DUF87 PF01935.12 CCC67434.1 - 0.0012 18.7 6.6 0.33 10.7 0.0 4.5 5 0 0 5 5 4 1 Domain of unknown function DUF87 PduV-EutP PF10662.4 CCC67434.1 - 0.0029 17.0 0.0 0.34 10.4 0.0 3.4 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation HEAT_EZ PF13513.1 CCC67434.1 - 0.0029 18.0 9.1 0.84 10.2 0.1 5.5 5 2 1 6 6 5 1 HEAT-like repeat AAA_25 PF13481.1 CCC67434.1 - 0.0042 16.5 0.0 1.9 7.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 CCC67434.1 - 0.0079 15.6 0.0 4.7 6.6 0.0 3.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 CCC67434.1 - 0.013 14.3 0.0 0.38 9.6 0.0 2.8 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CCC67434.1 - 0.02 14.4 2.1 1.9 7.8 0.0 3.5 4 0 0 4 4 4 0 FtsK/SpoIIIE family Septin PF00735.13 CCC67434.1 - 0.022 13.8 0.2 1.3 7.9 0.0 2.6 3 0 0 3 3 2 0 Septin Adaptin_N PF01602.15 CCC67434.1 - 0.023 13.0 6.3 0.056 11.7 3.1 2.1 1 1 1 2 2 2 0 Adaptin N terminal region ATP_bind_1 PF03029.12 CCC67434.1 - 0.027 13.9 0.3 8.4 5.8 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 CCC67434.1 - 0.032 13.6 0.0 8.9 5.6 0.0 2.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Zeta_toxin PF06414.7 CCC67434.1 - 0.038 13.0 0.1 8.9 5.3 0.0 2.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 CCC67434.1 - 0.043 13.5 0.1 5.7 6.7 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain Mg_chelatase PF01078.16 CCC67434.1 - 0.059 12.5 0.3 1 8.4 0.0 2.7 3 0 0 3 3 2 0 Magnesium chelatase, subunit ChlI AAA_13 PF13166.1 CCC67434.1 - 0.094 11.1 14.9 1.9 6.8 0.0 4.6 4 2 0 4 4 3 0 AAA domain ATP-synt_ab PF00006.20 CCC67434.1 - 0.11 11.9 0.0 7.7 5.9 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HEAT PF02985.17 CCC67434.1 - 0.23 11.6 3.4 40 4.6 0.0 4.7 5 0 0 5 5 4 0 HEAT repeat Pkinase PF00069.20 CCC67435.1 - 1e-58 198.5 0.0 4.2e-58 196.5 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67435.1 - 2.1e-23 82.7 0.0 3.3e-21 75.5 0.0 2.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC67435.1 - 8.9e-06 24.8 0.2 0.1 11.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CCC67435.1 - 0.0031 16.6 0.0 0.0066 15.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PBP1_TM PF14812.1 CCC67435.1 - 2.1 8.7 13.5 0.85 9.9 1.7 2.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SNF2_N PF00176.18 CCC67436.1 - 3.3e-43 147.6 0.0 9.2e-43 146.1 0.0 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 CCC67436.1 - 3.1e-10 39.7 7.9 8.4e-10 38.3 5.5 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCC67436.1 - 6.1e-09 35.4 10.0 1.6e-08 34.0 6.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC67436.1 - 8.7e-09 35.2 10.8 2.3e-08 33.9 7.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCC67436.1 - 4.3e-08 32.7 8.0 8.5e-08 31.7 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCC67436.1 - 3.5e-07 30.2 3.6 9.3e-07 28.8 2.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CCC67436.1 - 1.2e-06 28.1 9.6 3e-06 26.8 6.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCC67436.1 - 0.00032 20.5 9.0 0.00081 19.2 6.2 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 CCC67436.1 - 0.011 15.5 3.2 0.024 14.4 2.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Helicase_C PF00271.26 CCC67436.1 - 0.021 14.6 0.0 0.072 12.9 0.0 1.9 1 0 0 1 1 1 0 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.1 CCC67436.1 - 0.034 13.8 9.8 0.16 11.7 6.8 2.3 1 0 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 CCC67436.1 - 0.043 13.2 8.1 0.13 11.7 5.6 1.8 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_6 PF14835.1 CCC67436.1 - 0.12 12.2 1.9 0.42 10.4 1.3 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 CCC67436.1 - 0.12 11.9 2.5 0.27 10.7 1.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Nse PF11789.3 CCC67436.1 - 0.13 11.8 4.8 0.41 10.2 3.3 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 CCC67436.1 - 1.2 8.7 7.3 3.1 7.4 5.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Ribosomal_L37e PF01907.14 CCC67436.1 - 1.5 8.6 5.8 0.49 10.2 1.8 1.8 2 0 0 2 2 2 0 Ribosomal protein L37e Clat_adaptor_s PF01217.15 CCC67437.1 - 9.3e-55 184.2 0.2 1.1e-54 184.0 0.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TP_methylase PF00590.15 CCC67438.1 - 2.7e-24 86.0 0.0 4e-24 85.4 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases DUF4434 PF14488.1 CCC67438.1 - 0.012 15.4 0.1 0.033 13.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) DUF3357 PF11837.3 CCC67439.1 - 0.094 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) ABC1 PF03109.11 CCC67440.1 - 1.6e-30 105.5 0.0 3.2e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CCC67440.1 - 0.00032 20.1 0.0 0.0013 18.1 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Tubulin-binding PF00418.14 CCC67441.1 - 0.11 12.2 0.3 0.28 10.8 0.2 1.7 1 0 0 1 1 1 0 Tau and MAP protein, tubulin-binding repeat Zn_clus PF00172.13 CCC67442.1 - 4.6e-08 32.8 8.4 8.6e-08 31.9 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CCC67442.1 - 0.025 13.4 21.6 0.14 10.9 14.9 2.5 1 1 0 1 1 1 0 Fungal specific transcription factor domain KCNQC3-Ank-G_bd PF11956.3 CCC67443.1 - 0.025 14.6 0.6 0.68 10.0 0.0 2.4 2 0 0 2 2 2 0 Ankyrin-G binding motif of KCNQ2-3 TPR_MLP1_2 PF07926.7 CCC67444.1 - 0.0016 18.2 16.3 0.0016 18.2 11.3 1.8 1 1 0 1 1 1 1 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 CCC67444.1 - 0.0019 16.9 12.9 0.0021 16.7 8.9 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein bZIP_2 PF07716.10 CCC67444.1 - 0.0024 17.6 2.9 0.0024 17.6 2.0 3.6 1 1 2 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.16 CCC67444.1 - 0.015 15.2 4.5 0.015 15.2 3.1 2.7 2 0 0 2 2 2 0 bZIP transcription factor Reo_sigmaC PF04582.7 CCC67444.1 - 0.028 13.6 2.0 0.13 11.3 0.4 2.0 1 1 0 2 2 2 0 Reovirus sigma C capsid protein DUF3373 PF11853.3 CCC67444.1 - 0.035 12.6 3.7 0.034 12.6 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) GAS PF13851.1 CCC67444.1 - 0.036 13.2 20.8 0.1 11.7 14.4 1.7 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 CCC67444.1 - 0.037 13.6 20.7 0.088 12.3 7.4 2.2 1 1 1 2 2 2 0 IncA protein HemX PF04375.9 CCC67444.1 - 0.048 12.2 9.7 0.069 11.7 6.7 1.1 1 0 0 1 1 1 0 HemX GLE1 PF07817.8 CCC67444.1 - 0.15 10.9 4.0 0.23 10.3 2.8 1.3 1 0 0 1 1 1 0 GLE1-like protein Macoilin PF09726.4 CCC67444.1 - 0.21 9.8 11.7 0.24 9.6 8.1 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF972 PF06156.8 CCC67444.1 - 0.24 11.7 19.7 0.11 12.8 3.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) YlqD PF11068.3 CCC67444.1 - 0.24 11.4 13.7 0.3 11.1 8.9 1.5 1 1 0 1 1 1 0 YlqD protein CENP-Q PF13094.1 CCC67444.1 - 0.29 11.1 20.6 0.56 10.2 14.3 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.7 CCC67444.1 - 0.36 11.2 14.6 3.5 8.0 8.5 3.2 1 1 2 3 3 3 0 SlyX ADIP PF11559.3 CCC67444.1 - 0.43 10.4 16.4 0.18 11.7 8.6 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF904 PF06005.7 CCC67444.1 - 0.44 10.8 26.5 0.5 10.6 5.0 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF904) Exonuc_VII_L PF02601.10 CCC67444.1 - 0.47 9.6 9.0 0.51 9.4 6.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 CCC67444.1 - 0.75 8.1 10.7 0.99 7.7 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF724 PF05266.9 CCC67444.1 - 0.93 9.0 15.4 2.8 7.5 10.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) APG6 PF04111.7 CCC67444.1 - 1.1 8.2 18.1 1.6 7.6 12.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 CCC67444.1 - 1.2 8.0 8.8 1.4 7.7 6.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Laminin_II PF06009.7 CCC67444.1 - 1.3 8.7 11.6 2.4 7.8 8.1 1.5 1 0 0 1 1 1 0 Laminin Domain II I_LWEQ PF01608.12 CCC67444.1 - 2.7 7.8 9.1 4.7 7.1 6.3 1.3 1 0 0 1 1 1 0 I/LWEQ domain Ax_dynein_light PF10211.4 CCC67444.1 - 3.5 7.4 17.8 2.9 7.7 5.4 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain Lge1 PF11488.3 CCC67444.1 - 3.6 7.8 15.2 1.9 8.7 6.5 2.9 1 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 Med9 PF07544.8 CCC67444.1 - 5.4 6.8 10.2 11 5.8 5.9 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Glycogen_syn PF05693.8 CCC67445.1 - 0 1107.2 0.0 0 1107.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CCC67445.1 - 1.1e-09 37.9 0.0 1e-06 28.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCC67445.1 - 1.5e-05 25.1 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Pkinase PF00069.20 CCC67446.1 - 2e-71 240.2 0.0 2.7e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67446.1 - 3.1e-40 137.8 0.0 4.5e-40 137.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CCC67446.1 - 0.014 14.7 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 CCC67446.1 - 0.17 11.6 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family WHIM1 PF15612.1 CCC67447.1 - 0.0011 18.7 0.0 0.0029 17.4 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 U5_2-snRNA_bdg PF10597.4 CCC67447.1 - 0.037 13.6 0.3 0.091 12.3 0.2 1.6 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 SNARE PF05739.14 CCC67448.1 - 7.2e-16 57.6 3.2 1.3e-15 56.8 1.4 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CCC67448.1 - 1e-05 25.5 0.6 1e-05 25.5 0.4 2.6 1 1 2 3 3 3 1 Syntaxin DUF3357 PF11837.3 CCC67448.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) SUR7 PF06687.7 CCC67449.1 - 1e-19 70.9 20.1 1.7e-19 70.2 13.9 1.3 1 0 0 1 1 1 1 SUR7/PalI family PAT1 PF09770.4 CCC67449.1 - 9.2 4.3 28.2 13 3.8 19.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AA_permease PF00324.16 CCC67450.1 - 1.7e-122 409.1 41.5 2e-122 408.9 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC67450.1 - 4.2e-34 117.8 42.8 5.3e-34 117.4 29.6 1.1 1 0 0 1 1 1 1 Amino acid permease PDCD2_C PF04194.8 CCC67451.1 - 1.7e-43 148.0 0.2 2.9e-41 140.8 0.0 2.5 2 1 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain AAA_10 PF12846.2 CCC67451.1 - 0.0085 15.5 0.1 0.014 14.8 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain GTP_EFTU PF00009.22 CCC67452.1 - 7.4e-32 110.3 8.8 1e-31 109.8 3.4 2.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CCC67452.1 - 1.4e-21 76.4 0.1 3.6e-21 75.0 0.1 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.10 CCC67452.1 - 3.1e-09 36.3 0.0 8.3e-09 34.9 0.0 1.8 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region GTP_EFTU_D2 PF03144.20 CCC67452.1 - 5.4e-08 32.8 7.0 0.00037 20.5 0.4 3.2 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCC67452.1 - 5.6e-07 29.5 0.4 1.7e-06 27.9 0.3 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCC67452.1 - 1.6e-06 28.5 1.1 1.1e-05 25.9 0.2 2.6 2 0 0 2 2 2 1 Miro-like protein FeoB_N PF02421.13 CCC67452.1 - 0.0006 19.1 0.6 0.0024 17.1 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 CCC67452.1 - 0.0073 15.5 0.1 0.02 14.0 0.1 1.8 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CCC67452.1 - 0.0093 15.3 0.1 0.031 13.6 0.0 2.0 1 1 0 1 1 1 1 Ras family Dynamin_N PF00350.18 CCC67452.1 - 0.015 15.1 3.5 2.4 7.9 0.1 3.5 2 1 1 3 3 3 0 Dynamin family PduV-EutP PF10662.4 CCC67452.1 - 0.03 13.7 1.7 0.16 11.4 0.7 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TIP120 PF08623.5 CCC67453.1 - 2.6e-05 23.8 5.5 5.6e-05 22.7 0.1 3.2 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) WD40 PF00400.27 CCC67454.1 - 9.9e-10 37.9 0.2 0.00075 19.2 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CCC67454.1 - 0.0018 17.1 3.2 0.061 12.1 0.3 2.3 1 1 0 2 2 2 2 Coatomer WD associated region Arrestin_C PF02752.17 CCC67455.1 - 3.7e-21 75.6 1.3 1.7e-20 73.5 0.0 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCC67455.1 - 6.3e-11 42.3 0.3 1.5e-09 37.8 0.0 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CCC67455.1 - 2.9e-06 26.9 0.0 7.8e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Arrestin_N terminal like RRM_1 PF00076.17 CCC67456.1 - 6.6e-44 147.4 9.2 1.1e-14 53.8 0.1 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC67456.1 - 3.2e-30 103.9 1.9 5.2e-09 35.9 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC67456.1 - 2.4e-18 65.7 6.0 0.0004 20.1 0.5 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCC67456.1 - 8.9e-05 22.1 0.1 2.7 7.8 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 CCC67456.1 - 0.0023 17.6 0.3 0.13 12.0 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CCC67456.1 - 0.0027 17.5 0.6 3.5 7.5 0.0 4.4 5 0 0 5 5 5 1 RNA binding motif DUF500 PF04366.7 CCC67457.1 - 2.4e-44 149.7 0.4 4.9e-44 148.7 0.3 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CCC67457.1 - 8.9e-16 57.0 0.1 8.9e-16 57.0 0.0 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CCC67457.1 - 2.1e-15 56.0 0.0 4.2e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCC67457.1 - 6.7e-13 47.9 0.0 1.4e-12 46.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DUF1776 PF08643.5 CCC67458.1 - 2.1e-34 119.0 0.5 3.2e-34 118.4 0.4 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Lyase_1 PF00206.15 CCC67459.1 - 1.6e-96 323.2 0.0 2.2e-96 322.7 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 CCC67459.1 - 2.7e-26 91.4 0.1 7.4e-26 90.0 0.0 1.8 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal tRNA-synt_2 PF00152.15 CCC67460.1 - 2.6e-75 253.2 0.0 4.3e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCC67460.1 - 2.9e-13 49.4 0.3 5.3e-13 48.6 0.2 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Ins134_P3_kin PF05770.6 CCC67460.1 - 0.021 13.8 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 Inositol 1, 3, 4-trisphosphate 5/6-kinase HIT PF01230.18 CCC67460.1 - 0.47 11.0 1.8 0.57 10.7 0.1 2.0 2 0 0 2 2 2 0 HIT domain ProRS-C_1 PF09180.6 CCC67461.1 - 3.2e-25 87.8 5.4 3.8e-25 87.5 1.5 2.6 3 0 0 3 3 3 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 CCC67461.1 - 1.7e-22 79.8 0.0 2.9e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCC67461.1 - 3.5e-20 71.7 0.1 9.8e-20 70.3 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 CCC67461.1 - 0.065 13.0 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Aminoacyl-tRNA editing domain DSPn PF14671.1 CCC67462.1 - 8.6e-51 171.6 0.0 4.9e-50 169.1 0.0 2.0 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CCC67462.1 - 7.6e-23 80.5 0.0 1.5e-21 76.3 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCC67462.1 - 2.7e-05 23.6 0.1 7.9e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 CCC67462.1 - 0.00018 20.9 0.1 0.00036 20.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 CCC67462.1 - 0.00063 19.8 0.0 0.0016 18.5 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CCC67462.1 - 0.11 12.7 0.2 0.37 11.0 0.0 2.0 2 0 0 2 2 2 0 Tyrosine phosphatase family BPL_LplA_LipB PF03099.14 CCC67463.1 - 2.7e-17 62.9 0.1 4.7e-17 62.1 0.1 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF2012 PF09430.5 CCC67463.1 - 0.046 13.5 0.0 0.088 12.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2012) UPF0086 PF01868.11 CCC67464.1 - 4.6e-15 55.0 0.0 8.3e-15 54.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Cullin PF00888.17 CCC67465.1 - 7.7e-15 54.4 3.6 9.6e-15 54.1 0.7 2.2 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 CCC67465.1 - 0.018 14.8 0.1 0.18 11.6 0.0 2.6 2 0 0 2 2 2 0 Cullin protein neddylation domain RE_TaqI PF09573.5 CCC67465.1 - 0.024 13.7 0.0 0.068 12.2 0.0 1.7 1 0 0 1 1 1 0 TaqI restriction endonuclease Urotensin_II PF02083.10 CCC67465.1 - 1.6 8.1 4.7 3.4 7.1 3.2 1.5 1 0 0 1 1 1 0 Urotensin II Snf7 PF03357.16 CCC67466.1 - 1.5e-10 40.7 18.2 1.5e-10 40.7 12.6 1.9 1 1 1 2 2 2 1 Snf7 DUF3211 PF11485.3 CCC67466.1 - 0.0081 16.1 2.7 0.0081 16.1 1.9 2.6 2 2 2 4 4 4 1 Protein of unknown function (DUF3211) Sigma_reg_N PF13800.1 CCC67467.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Amidohydro_2 PF04909.9 CCC67468.1 - 2.4e-21 76.4 0.0 2.9e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase DUF1317 PF07026.6 CCC67468.1 - 0.1 12.5 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1317) rRNA_proc-arch PF13234.1 CCC67469.1 - 3.1e-92 308.5 1.0 3.1e-92 308.5 0.7 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 CCC67469.1 - 1.3e-62 210.2 0.2 3.9e-62 208.6 0.2 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CCC67469.1 - 2.3e-22 79.2 0.0 3e-21 75.6 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC67469.1 - 2.7e-06 27.1 0.0 6.7e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF964 PF06133.6 CCC67469.1 - 0.054 13.5 6.1 4 7.4 0.4 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF964) AAA_19 PF13245.1 CCC67469.1 - 0.2 11.4 0.0 0.62 9.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Vps26 PF03643.10 CCC67471.1 - 1.7e-111 371.4 0.0 2e-111 371.2 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 CCC67471.1 - 0.0029 17.4 0.2 0.018 14.8 0.1 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 CCC67471.1 - 0.059 13.4 1.7 0.083 12.9 0.1 2.0 2 1 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Tim54 PF11711.3 CCC67472.1 - 1.8e-127 425.1 0.7 2.1e-127 424.9 0.5 1.0 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 EphA2_TM PF14575.1 CCC67472.1 - 0.036 14.4 0.8 0.082 13.3 0.5 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Lysine_decarbox PF03641.9 CCC67473.1 - 7.5e-46 155.2 0.2 9.5e-46 154.9 0.1 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase zf-H2C2_2 PF13465.1 CCC67474.1 - 1.9e-26 90.9 50.8 1.8e-08 34.2 0.4 7.7 8 0 0 8 8 8 5 Zinc-finger double domain zf-C2H2 PF00096.21 CCC67474.1 - 7e-24 82.6 68.8 1.9e-05 24.7 1.6 8.7 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC67474.1 - 1.1e-17 63.0 54.0 0.0015 18.7 1.8 9.0 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCC67474.1 - 2.3e-06 27.3 40.4 0.0078 16.0 1.1 7.3 6 1 1 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCC67474.1 - 5.1e-06 26.4 12.9 0.00013 22.0 1.5 7.8 9 0 0 9 9 9 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCC67474.1 - 0.00036 20.6 2.5 0.00036 20.6 1.7 7.1 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 CCC67474.1 - 0.0016 18.0 19.9 0.079 12.6 0.6 5.3 5 0 0 5 5 5 3 zinc-finger of a C2HC-type zf-BED PF02892.10 CCC67474.1 - 4.7 7.0 36.5 0.8 9.5 6.4 5.9 3 1 1 4 4 4 0 BED zinc finger Pkinase PF00069.20 CCC67475.1 - 2.3e-34 118.7 0.0 1.5e-33 116.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67475.1 - 6.1e-17 61.5 0.0 4e-16 58.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCC67475.1 - 0.058 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zinc_ribbon_2 PF13240.1 CCC67475.1 - 0.12 11.8 0.1 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 zinc-ribbon domain HbrB PF08539.6 CCC67476.1 - 1.6e-19 70.3 5.7 3.2e-19 69.3 3.9 1.5 1 0 0 1 1 1 1 HbrB-like CLN3 PF02487.12 CCC67477.1 - 1.2e-140 468.9 23.6 3e-139 464.2 16.3 2.0 1 1 0 1 1 1 1 CLN3 protein Aminotran_1_2 PF00155.16 CCC67478.1 - 2.7e-86 289.7 0.0 3.4e-86 289.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CCC67478.1 - 4.5e-05 22.6 0.0 7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 CCC67478.1 - 0.00016 20.0 0.1 0.0004 18.7 0.1 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CCC67478.1 - 0.0089 14.8 0.1 0.028 13.1 0.1 1.7 1 1 0 1 1 1 1 Aminotransferase class-V DUF2240 PF09999.4 CCC67478.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) Nup54 PF13874.1 CCC67479.1 - 4.4 6.9 15.2 2.3 7.8 7.3 2.4 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Phosphodiest PF01663.17 CCC67480.1 - 3.8e-13 49.5 6.0 1.5e-10 40.9 4.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CCC67480.1 - 2.4e-05 23.8 0.7 4.6e-05 22.9 0.5 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 CCC67480.1 - 0.019 14.1 0.1 0.038 13.1 0.1 1.6 1 0 0 1 1 1 0 Sulfatase CBFD_NFYB_HMF PF00808.18 CCC67481.1 - 0.0017 18.3 0.0 0.008 16.2 0.0 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3901 PF13040.1 CCC67481.1 - 0.38 10.0 1.4 0.98 8.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3901) Esterase PF00756.15 CCC67483.1 - 1.6e-56 191.5 0.1 1.8e-56 191.3 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 CCC67483.1 - 2.4e-05 24.1 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCC67483.1 - 0.00033 19.9 0.0 0.0005 19.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family WD40 PF00400.27 CCC67484.1 - 2.8e-16 58.7 0.2 3.7e-05 23.4 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCC67484.1 - 0.00011 21.6 0.0 0.02 14.3 0.0 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Spc42p PF11544.3 CCC67485.1 - 1.4e-07 31.3 9.6 1.4e-07 31.3 6.6 3.5 2 2 1 3 3 3 1 Spindle pole body component Spc42p Fib_alpha PF08702.5 CCC67485.1 - 2.5 8.2 18.1 0.085 12.9 3.8 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF2019 PF09450.5 CCC67485.1 - 3 7.7 5.4 4.4 7.2 0.1 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF2019) DUF1664 PF07889.7 CCC67485.1 - 9.6 6.0 11.3 0.55 10.0 2.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_11 PF13414.1 CCC67486.1 - 0.012 15.2 1.4 0.027 14.1 0.0 2.4 2 0 0 2 2 2 0 TPR repeat DUF4381 PF14316.1 CCC67486.1 - 0.52 10.4 0.0 0.52 10.4 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4381) Med15 PF09606.5 CCC67486.1 - 3.4 5.7 72.7 4.4 5.3 50.4 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal A_deaminase PF00962.17 CCC67487.1 - 3.6e-14 52.4 0.0 1.1e-09 37.6 0.0 3.2 3 0 0 3 3 3 3 Adenosine/AMP deaminase DUF619 PF04768.8 CCC67488.1 - 2.3e-48 163.8 1.3 3.1e-48 163.3 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Sld5 PF05916.6 CCC67489.1 - 5.2e-17 62.1 1.6 1.1e-16 61.0 1.1 1.5 1 0 0 1 1 1 1 GINS complex protein DnaJ PF00226.26 CCC67490.1 - 8.6e-21 73.4 4.1 2.8e-20 71.7 2.8 2.0 1 0 0 1 1 1 1 DnaJ domain Band_3_cyto PF07565.8 CCC67490.1 - 1.7 8.0 12.2 8 5.8 7.3 2.2 1 1 1 2 2 2 0 Band 3 cytoplasmic domain SMC_N PF02463.14 CCC67491.1 - 4.6e-55 186.2 49.1 1.4e-54 184.6 34.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCC67491.1 - 1e-30 106.1 0.0 1.2e-29 102.6 0.0 2.9 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CCC67491.1 - 2.1e-19 70.6 5.3 2.1e-19 70.6 3.7 6.9 3 2 4 7 7 7 1 AAA domain AAA_21 PF13304.1 CCC67491.1 - 7.4e-12 45.8 10.7 8.8e-08 32.4 4.3 6.2 2 1 3 6 6 6 2 AAA domain AAA_29 PF13555.1 CCC67491.1 - 0.0014 18.1 0.0 0.0034 16.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain BLOC1_2 PF10046.4 CCC67491.1 - 0.0064 16.6 2.1 0.0064 16.6 1.5 10.7 5 3 7 12 12 12 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin-6_N PF09177.6 CCC67491.1 - 3.7 8.0 76.5 0.1 13.0 5.9 9.2 4 3 4 8 8 8 0 Syntaxin 6, N-terminal Cytokin_check_N PF10407.4 CCC67492.1 - 3e-26 90.8 1.4 7.5e-26 89.5 0.9 1.7 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus CAP PF00188.21 CCC67493.1 - 2.2e-19 70.1 3.3 4e-19 69.3 2.3 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family RNase_H PF00075.19 CCC67493.1 - 0.048 13.9 1.2 0.078 13.3 0.9 1.3 1 0 0 1 1 1 0 RNase H KH_1 PF00013.24 CCC67494.1 - 2.3e-74 244.9 34.9 4.3e-12 45.5 0.4 11.8 12 1 0 12 12 12 8 KH domain KH_3 PF13014.1 CCC67494.1 - 8.9e-48 159.2 26.0 1.9e-08 33.7 0.0 10.1 9 0 0 9 9 9 8 KH domain KH_2 PF07650.12 CCC67494.1 - 1.4e-11 43.7 22.6 0.0005 19.5 0.0 7.2 6 1 0 7 7 7 3 KH domain SLS PF14611.1 CCC67494.1 - 6e-06 25.8 18.6 0.47 9.8 1.4 7.5 5 4 4 9 9 9 3 Mitochondrial inner-membrane-bound regulator STAS PF01740.16 CCC67494.1 - 0.0024 17.2 0.1 0.011 15.1 0.0 2.1 2 0 0 2 2 2 1 STAS domain KH_4 PF13083.1 CCC67494.1 - 0.013 15.0 5.9 2.9 7.5 0.0 5.6 5 0 0 5 5 5 0 KH domain EF-hand_4 PF12763.2 CCC67495.1 - 0.0054 16.4 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Arrestin_C PF02752.17 CCC67496.1 - 4.6e-13 49.4 0.6 5.7e-12 45.8 0.1 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCC67496.1 - 5.2e-08 32.8 0.0 0.00016 21.4 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Exo70 PF03081.10 CCC67497.1 - 2.4e-82 276.6 4.3 2.4e-82 276.6 3.0 1.9 2 0 0 2 2 2 1 Exo70 exocyst complex subunit Cytochrom_B562 PF07361.6 CCC67497.1 - 0.028 14.7 1.2 3 8.2 0.2 2.8 2 0 0 2 2 2 0 Cytochrome b562 Vps51 PF08700.6 CCC67497.1 - 0.17 11.7 4.2 0.23 11.3 0.1 3.0 3 0 0 3 3 3 0 Vps51/Vps67 DUF1825 PF08855.5 CCC67497.1 - 0.68 9.9 4.9 0.92 9.5 1.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1825) OTCace PF00185.19 CCC67498.1 - 9.9e-44 148.9 0.6 2.3e-43 147.7 0.2 1.7 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.16 CCC67498.1 - 4e-41 139.9 0.4 7.2e-41 139.1 0.1 1.6 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain Zn_clus PF00172.13 CCC67499.1 - 1.1e-08 34.8 12.4 2.3e-08 33.8 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRCT PF00533.21 CCC67500.1 - 5.7e-17 61.6 2.9 1e-05 25.6 0.0 4.6 4 1 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCC67500.1 - 1.9e-11 43.6 0.2 1.5e-05 24.7 0.0 4.5 4 0 0 4 4 4 3 twin BRCT domain Pneumo_phosprot PF02478.11 CCC67500.1 - 1.8 8.0 9.0 0.95 8.9 3.2 2.3 2 1 0 2 2 2 0 Pneumovirus phosphoprotein GWT1 PF06423.7 CCC67501.1 - 1.4e-46 157.9 3.1 4.3e-46 156.3 2.2 1.9 1 0 0 1 1 1 1 GWT1 OCIA PF07051.6 CCC67501.1 - 0.13 11.6 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 Ovarian carcinoma immunoreactive antigen (OCIA) UvrD_C PF13361.1 CCC67502.1 - 9.1e-69 232.5 0.0 3e-66 224.3 0.0 2.6 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CCC67502.1 - 8.2e-63 212.5 0.1 8.2e-63 212.5 0.1 3.1 3 1 0 3 3 3 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.1 CCC67502.1 - 3e-12 46.1 0.0 9.9e-12 44.4 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 CCC67502.1 - 4.4e-09 36.4 0.0 4e-06 26.9 0.0 2.8 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.1 CCC67502.1 - 0.00064 19.3 0.0 0.0017 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 CCC67502.1 - 0.014 15.0 0.0 0.044 13.4 0.0 1.9 1 0 0 1 1 1 0 Helicase Ion_trans_2 PF07885.11 CCC67503.1 - 2.5e-25 87.9 33.3 8.4e-15 54.2 6.8 3.3 3 0 0 3 3 3 2 Ion channel Lig_chan PF00060.21 CCC67503.1 - 0.066 12.9 8.1 6.2 6.5 0.5 3.9 2 2 1 3 3 3 0 Ligand-gated ion channel Na_H_Exchanger PF00999.16 CCC67504.1 - 4.8e-65 219.5 34.7 7.2e-65 218.9 24.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pkinase PF00069.20 CCC67505.1 - 1.8e-66 223.9 0.0 3.6e-66 222.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67505.1 - 3.2e-44 150.9 0.0 5.6e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC67505.1 - 3.2e-10 39.4 0.0 1.7e-07 30.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CCC67505.1 - 0.22 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L21p PF00829.16 CCC67506.1 - 0.00031 20.8 0.0 0.00043 20.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein PTPLA PF04387.9 CCC67507.1 - 2.8e-48 163.4 12.2 3.8e-48 163.0 8.5 1.2 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA SAPS PF04499.10 CCC67508.1 - 1e-164 548.6 0.4 1e-164 548.6 0.2 3.4 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein Arm PF00514.18 CCC67508.1 - 0.016 15.0 0.0 0.085 12.7 0.0 2.3 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat ChAPs PF09295.5 CCC67509.1 - 5.5e-44 150.5 4.1 9.7e-36 123.3 0.3 2.2 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 CCC67509.1 - 1.7e-07 30.7 0.5 0.00019 21.0 0.0 3.1 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 CCC67509.1 - 0.00016 21.3 1.3 0.14 12.1 0.1 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCC67509.1 - 0.00016 21.5 0.3 0.27 11.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCC67509.1 - 0.0017 17.9 0.0 0.29 11.0 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CCC67509.1 - 0.0031 17.5 0.3 0.051 13.7 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 CCC67509.1 - 0.0083 15.7 0.4 0.12 12.0 0.1 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCC67509.1 - 0.047 13.9 0.0 0.26 11.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PI3_PI4_kinase PF00454.22 CCC67510.1 - 2.1e-59 200.8 0.1 3e-59 200.3 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase GTP_EFTU PF00009.22 CCC67511.1 - 1.1e-57 194.4 0.1 2e-57 193.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 CCC67511.1 - 1.9e-25 88.5 0.1 4.5e-25 87.2 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CCC67511.1 - 1e-15 57.3 0.2 2.5e-14 52.8 0.2 2.5 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCC67511.1 - 4.5e-11 42.7 2.1 5.6e-11 42.3 0.5 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCC67511.1 - 9e-06 25.6 0.0 2.8e-05 24.0 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Zn_clus PF00172.13 CCC67512.1 - 7.4e-06 25.7 12.1 1.5e-05 24.7 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 CCC67512.1 - 0.0048 17.2 0.0 0.013 15.8 0.0 1.7 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 CCC67512.1 - 0.031 14.0 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 PAS fold PAS_8 PF13188.1 CCC67512.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 PAS domain Pam16 PF03656.8 CCC67513.1 - 4.5e-52 175.1 0.1 5.4e-52 174.9 0.1 1.0 1 0 0 1 1 1 1 Pam16 STb_secrete PF09075.5 CCC67513.1 - 0.065 13.0 0.3 0.73 9.7 0.0 2.2 1 1 1 2 2 2 0 Heat-stable enterotoxin B, secretory NTP_transferase PF00483.18 CCC67513.1 - 0.071 12.3 0.0 0.077 12.2 0.0 1.2 1 0 0 1 1 1 0 Nucleotidyl transferase MATH PF00917.21 CCC67513.1 - 0.11 12.6 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 MATH domain SET PF00856.23 CCC67514.1 - 7.4e-05 23.1 0.0 0.00024 21.4 0.0 1.9 1 0 0 1 1 1 1 SET domain PHD PF00628.24 CCC67514.1 - 0.00039 20.0 8.0 0.001 18.7 5.6 1.8 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCC67514.1 - 0.0047 16.1 5.2 0.014 14.6 3.6 1.8 1 0 0 1 1 1 1 PHD-finger Pkinase PF00069.20 CCC67515.1 - 5.2e-54 183.1 0.1 8.5e-52 175.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67515.1 - 3.7e-27 95.0 0.1 3.3e-26 91.9 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.9 CCC67515.1 - 0.026 13.5 0.1 0.044 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RNA_lig_T4_1 PF09511.5 CCC67516.1 - 6.3e-76 254.7 0.0 1.3e-75 253.7 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 CCC67516.1 - 1.3e-72 243.0 0.5 1.6e-71 239.5 0.0 2.7 3 0 0 3 3 3 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 CCC67516.1 - 2e-57 194.3 5.3 3.1e-57 193.7 3.7 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain MSP7_C PF12948.2 CCC67516.1 - 0.012 15.8 1.6 0.028 14.6 0.7 2.0 1 1 0 1 1 1 0 MSP7-like protein C-terminal domain LigT_PEase PF02834.11 CCC67516.1 - 0.14 12.1 0.0 28 4.8 0.0 2.7 2 0 0 2 2 2 0 LigT like Phosphoesterase BP28CT PF08146.7 CCC67517.1 - 9.6e-43 145.5 3.5 9.6e-43 145.5 2.4 4.6 5 0 0 5 5 5 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 CCC67517.1 - 7.6e-21 74.2 1.3 7.6e-21 74.2 0.9 4.0 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 HEAT_2 PF13646.1 CCC67517.1 - 0.0024 18.1 0.4 5.1 7.4 0.0 4.5 4 0 0 4 4 4 1 HEAT repeats HEAT PF02985.17 CCC67517.1 - 0.013 15.5 3.4 3.2 8.0 0.1 4.3 3 0 0 3 3 3 0 HEAT repeat HEAT_EZ PF13513.1 CCC67517.1 - 0.091 13.2 1.2 2.5 8.6 0.1 3.7 3 0 0 3 3 3 0 HEAT-like repeat GATA PF00320.22 CCC67518.1 - 2.1e-14 52.5 3.0 3.7e-14 51.7 2.1 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CCC67518.1 - 0.0082 15.4 0.4 0.016 14.5 0.3 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding WD40 PF00400.27 CCC67519.1 - 4.2e-36 121.5 11.9 1.1e-09 37.8 0.1 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 CCC67519.1 - 4.6e-07 28.3 3.5 0.1 10.7 0.0 4.4 1 1 2 4 4 4 3 Nucleoporin Nup120/160 DUF3249 PF11615.3 CCC67519.1 - 1.7e-05 24.4 0.1 0.35 10.6 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF3249) PQQ_2 PF13360.1 CCC67519.1 - 0.0024 17.3 0.0 1.9 7.9 0.0 2.3 1 1 1 2 2 2 2 PQQ-like domain DUF3573 PF12097.3 CCC67521.1 - 0.075 11.6 7.1 0.081 11.5 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Gp-FAR-1 PF05823.7 CCC67521.1 - 0.11 12.3 8.0 0.071 13.0 3.9 1.7 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Peptidase_S64 PF08192.6 CCC67521.1 - 1.1 7.4 8.9 1.4 7.1 6.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Occludin_ELL PF07303.8 CCC67521.1 - 2.5 8.8 7.8 1.4 9.7 1.6 2.2 1 1 1 2 2 2 0 Occludin homology domain SNAPc_SNAP43 PF09808.4 CCC67521.1 - 2.7 7.6 10.6 1.3 8.6 0.9 2.2 1 1 1 2 2 2 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Phage_GPO PF05929.6 CCC67521.1 - 3.4 6.8 13.4 5.6 6.1 9.1 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Ly49 PF08391.5 CCC67521.1 - 8.9 6.4 7.5 3.5 7.7 3.1 1.8 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region RP-C_C PF11800.3 CCC67522.1 - 4.1 7.0 5.4 8.2 6.0 2.8 2.1 2 1 0 2 2 2 0 Replication protein C C-terminal region ASF1_hist_chap PF04729.8 CCC67523.1 - 1e-67 226.5 0.1 1.4e-67 226.1 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone CENP-T PF15511.1 CCC67523.1 - 0.73 9.0 28.6 0.92 8.6 19.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 CCC67523.1 - 0.85 7.4 45.0 1.1 7.0 31.2 1.2 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.7 CCC67523.1 - 0.86 7.8 38.0 1.2 7.4 26.4 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF2457 PF10446.4 CCC67523.1 - 0.98 8.0 36.9 1.5 7.4 25.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 CCC67523.1 - 1.9 6.8 40.6 2.6 6.4 28.1 1.2 1 0 0 1 1 1 0 Daxx Family Zip PF02535.17 CCC67523.1 - 7.7 5.4 8.5 11 4.9 5.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SUN PF03856.8 CCC67524.1 - 5.8e-102 340.2 12.9 8.6e-102 339.6 8.9 1.2 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) IL2 PF00715.12 CCC67524.1 - 0.011 15.4 0.1 0.53 9.9 0.0 2.3 2 0 0 2 2 2 0 Interleukin 2 Herpes_UL16 PF03044.9 CCC67524.1 - 0.035 13.1 0.4 0.055 12.4 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family zf-MYND PF01753.13 CCC67524.1 - 0.16 11.8 1.9 0.35 10.7 1.3 1.5 1 0 0 1 1 1 0 MYND finger Pho86 PF11124.3 CCC67525.1 - 5.1e-85 285.1 3.9 5.9e-85 284.9 2.7 1.0 1 0 0 1 1 1 1 Inorganic phosphate transporter Pho86 DUF3539 PF12058.3 CCC67525.1 - 0.0013 18.5 0.2 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3539) SUR7 PF06687.7 CCC67525.1 - 0.0058 16.2 5.1 0.0058 16.2 3.5 1.5 2 0 0 2 2 2 1 SUR7/PalI family GIDA PF01134.17 CCC67525.1 - 0.066 12.0 0.0 0.084 11.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Ribul_P_3_epim PF00834.14 CCC67526.1 - 1.7e-71 239.5 0.0 2e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family OMPdecase PF00215.19 CCC67526.1 - 0.0039 16.6 0.1 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.12 CCC67526.1 - 0.039 13.2 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 PcrB family QRPTase_C PF01729.14 CCC67526.1 - 0.086 12.3 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Alb1 PF09135.6 CCC67527.1 - 8.1e-15 55.3 10.7 8.1e-15 55.3 7.4 2.0 1 1 1 2 2 2 1 Alb1 DUF2413 PF10310.4 CCC67528.1 - 2.3e-113 379.3 32.2 2.7e-113 379.1 22.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Ndc1_Nup PF09531.5 CCC67528.1 - 0.6 8.4 10.9 1.1 7.6 7.6 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GCD14 PF08704.5 CCC67529.1 - 3.7e-82 275.5 0.1 1.4e-81 273.6 0.0 1.8 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit RrnaAD PF00398.15 CCC67529.1 - 1.1e-05 24.6 0.0 2.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 CCC67529.1 - 3.2e-05 24.4 0.0 7.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC67529.1 - 7.1e-05 22.4 0.0 0.00012 21.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCC67529.1 - 0.0001 22.2 0.0 0.00018 21.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC67529.1 - 0.0046 16.6 0.0 0.014 15.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CCC67529.1 - 0.022 13.8 0.5 0.15 11.1 0.0 2.5 2 2 0 2 2 2 0 Putative methyltransferase Gcd10p PF04189.8 CCC67529.1 - 0.03 13.4 1.2 0.18 10.9 0.0 2.1 2 0 0 2 2 2 0 Gcd10p family DUF3748 PF12566.3 CCC67529.1 - 0.035 14.0 0.0 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3748) PCMT PF01135.14 CCC67529.1 - 0.057 12.9 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ta0938 PF11494.3 CCC67529.1 - 0.073 13.1 0.1 0.25 11.4 0.0 1.9 1 0 0 1 1 1 0 Ta0938 Methyltransf_11 PF08241.7 CCC67529.1 - 0.12 12.9 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CN_hydrolase PF00795.17 CCC67530.1 - 3.9e-26 91.5 0.0 6e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase zf-H2C2 PF09337.5 CCC67531.1 - 6.5e-20 70.2 6.8 1.3e-19 69.3 4.7 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_1 PF00583.19 CCC67531.1 - 0.00062 19.7 0.0 0.0069 16.3 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Nop14 PF04147.7 CCC67531.1 - 0.1 10.4 24.5 0.14 10.0 17.0 1.2 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 CCC67531.1 - 0.36 10.0 19.2 0.92 8.7 13.3 1.6 1 0 0 1 1 1 0 NOA36 protein TFIIA PF03153.8 CCC67531.1 - 0.79 9.5 25.3 0.01 15.7 12.4 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.8 CCC67531.1 - 0.89 9.1 16.0 1.6 8.2 11.1 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region Usp PF00582.21 CCC67531.1 - 2.4 8.3 6.9 4.9 7.3 4.8 1.4 1 0 0 1 1 1 0 Universal stress protein family Telomerase_RBD PF12009.3 CCC67532.1 - 0.077 12.9 0.3 0.08 12.8 0.2 1.1 1 0 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain TAT_signal PF10518.4 CCC67532.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 TAT (twin-arginine translocation) pathway signal sequence Pkinase PF00069.20 CCC67533.1 - 9e-56 188.8 0.1 2.2e-55 187.6 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67533.1 - 7.9e-37 126.7 0.0 1.5e-36 125.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC67533.1 - 0.00019 20.4 0.0 0.0004 19.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CCC67533.1 - 0.0046 15.8 0.1 0.0046 15.8 0.1 1.6 2 0 0 2 2 2 1 Seadornavirus VP7 DDHD PF02862.12 CCC67533.1 - 0.11 12.3 15.1 0.05 13.3 6.3 2.3 2 0 0 2 2 2 0 DDHD domain TrkH PF02386.11 CCC67534.1 - 1.6e-136 454.5 9.0 2.8e-135 450.4 1.6 2.1 2 0 0 2 2 2 2 Cation transport protein CPSase_L_D2 PF02786.12 CCC67535.1 - 5.9e-115 381.8 1.4 5.7e-84 280.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 CCC67535.1 - 2.1e-46 156.6 0.0 5.4e-46 155.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 CCC67535.1 - 8.3e-44 149.3 0.0 1.9e-43 148.1 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 CCC67535.1 - 1.6e-41 141.2 0.0 3.2e-41 140.3 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_chain PF00289.17 CCC67535.1 - 2.1e-40 137.2 0.2 6e-20 71.3 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain CPSase_L_D3 PF02787.14 CCC67535.1 - 3.5e-39 133.3 0.2 1.2e-38 131.6 0.1 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.19 CCC67535.1 - 2.6e-35 121.6 0.1 5.9e-34 117.2 0.0 2.8 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATP-grasp_4 PF13535.1 CCC67535.1 - 7.9e-33 113.7 0.4 1.1e-20 74.1 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCC67535.1 - 4.5e-25 88.0 0.5 3.9e-14 52.1 0.0 3.4 3 0 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 CCC67535.1 - 1.6e-22 79.2 0.0 1.2e-21 76.4 0.0 2.7 1 0 0 1 1 1 1 MGS-like domain Dala_Dala_lig_C PF07478.8 CCC67535.1 - 8.3e-17 61.2 3.5 2e-09 37.1 0.4 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CCC67535.1 - 6.1e-15 54.9 0.8 6.8e-07 28.8 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain RimK PF08443.6 CCC67535.1 - 1.3e-07 31.3 0.4 2.2e-05 24.0 0.3 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 CCC67535.1 - 1.9e-06 27.8 1.5 0.012 15.4 0.2 2.8 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 CCC67535.1 - 3.3e-05 23.4 0.0 0.00083 18.8 0.0 2.4 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 CCC67535.1 - 0.024 14.0 0.0 0.069 12.6 0.0 1.7 1 0 0 1 1 1 0 DJ-1/PfpI family mIF3 PF14877.1 CCC67536.1 - 6.8e-57 191.7 10.0 6.8e-57 191.7 7.0 2.2 2 0 0 2 2 2 1 Mitochondrial translation initiation factor DUF4646 PF15496.1 CCC67536.1 - 0.089 12.8 0.2 0.38 10.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4646) Zn_dep_PLPC PF00882.13 CCC67537.1 - 2.4e-19 69.5 1.0 4.4e-19 68.7 0.7 1.4 1 0 0 1 1 1 1 Zinc dependent phospholipase C Mito_carr PF00153.22 CCC67538.1 - 2.8e-63 209.6 4.7 2.5e-21 75.1 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein AhpC-TSA_2 PF13911.1 CCC67538.1 - 0.017 14.9 0.0 0.025 14.5 0.0 1.4 1 1 0 1 1 1 0 AhpC/TSA antioxidant enzyme Ribosomal_L18e PF00828.14 CCC67539.1 - 8.4e-22 77.9 1.3 8.4e-22 77.9 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Acetyltransf_1 PF00583.19 CCC67540.1 - 3.1e-13 49.5 0.1 5e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 CCC67540.1 - 5.6e-07 29.6 0.3 6.4e-07 29.4 0.2 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCC67540.1 - 3.1e-05 24.0 0.0 3.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCC67540.1 - 0.00012 22.0 0.1 0.00015 21.7 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCC67540.1 - 0.00018 21.3 0.1 0.00027 20.8 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCC67540.1 - 0.00021 21.4 0.5 0.00026 21.1 0.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCC67540.1 - 0.0042 16.9 0.0 0.0081 16.0 0.0 1.5 1 1 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 CCC67540.1 - 0.0044 16.7 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 CCC67540.1 - 0.0065 16.5 0.1 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CCC67540.1 - 0.031 13.8 0.3 0.1 12.1 0.0 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2334 PF10096.4 CCC67540.1 - 0.037 13.4 0.0 0.056 12.8 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) RRM_1 PF00076.17 CCC67541.1 - 5.4e-19 67.6 0.4 1.1e-10 41.0 0.1 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC67541.1 - 3.6e-15 55.5 0.8 9.9e-07 28.5 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC67541.1 - 4.5e-14 52.1 0.1 1.4e-09 37.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Adaptin_N PF01602.15 CCC67542.1 - 8.7e-108 360.9 15.6 1.1e-107 360.5 10.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 CCC67542.1 - 1.4e-48 164.5 3.1 3.7e-48 163.1 2.1 1.8 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 CCC67542.1 - 7e-10 39.0 0.1 0.0062 16.7 0.0 4.5 3 2 0 3 3 3 2 HEAT repeats HEAT PF02985.17 CCC67542.1 - 0.002 18.0 2.3 23 5.3 0.0 5.8 6 0 0 6 6 6 1 HEAT repeat FTCD_C PF04961.7 CCC67542.1 - 0.061 12.7 0.2 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Rcd1 PF04078.8 CCC67543.1 - 2e-119 397.3 3.1 2.6e-119 396.8 2.1 1.2 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Dimer_Tnp_hAT PF05699.9 CCC67544.1 - 8.1e-09 34.9 0.2 3e-08 33.1 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 CCC67544.1 - 0.023 14.4 0.6 0.052 13.3 0.4 1.7 1 0 0 1 1 1 0 BED zinc finger Cyclin_N PF00134.18 CCC67545.1 - 1.1e-20 73.4 0.0 1.9e-20 72.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCC67545.1 - 4e-12 46.7 0.3 8.1e-12 45.7 0.0 1.7 2 1 0 2 2 2 1 Cyclin AAA PF00004.24 CCC67547.1 - 1.1e-17 64.5 0.0 2e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CCC67547.1 - 4.3e-17 62.2 0.0 6.4e-15 55.1 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CCC67547.1 - 7.8e-15 54.6 0.1 2e-14 53.3 0.1 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 CCC67547.1 - 8.4e-08 32.4 0.8 0.014 15.5 0.1 3.0 2 1 1 3 3 3 2 AAA domain Rad17 PF03215.10 CCC67547.1 - 1e-07 31.0 0.0 1.6e-06 27.1 0.0 2.2 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CCC67547.1 - 1.1e-06 27.9 0.0 3e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCC67547.1 - 1.4e-06 28.4 0.1 6e-05 23.1 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CCC67547.1 - 3.6e-06 26.8 0.0 8.9e-06 25.6 0.0 1.6 2 0 0 2 2 1 1 AAA domain DNA_pol3_delta PF06144.8 CCC67547.1 - 3e-05 23.6 0.1 4.9e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 CCC67547.1 - 5.2e-05 22.9 0.1 0.00015 21.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCC67547.1 - 5.8e-05 22.7 0.0 0.00011 21.8 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DUF815 PF05673.8 CCC67547.1 - 0.00012 21.1 0.0 0.00016 20.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 CCC67547.1 - 0.00039 19.8 0.0 0.00077 18.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 CCC67547.1 - 0.00045 21.0 0.1 0.0021 18.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCC67547.1 - 0.00046 19.9 0.0 0.0023 17.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CCC67547.1 - 0.0014 18.0 0.2 0.025 13.9 0.1 2.4 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 CCC67547.1 - 0.0015 18.0 0.1 0.014 14.9 0.1 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CCC67547.1 - 0.0015 18.3 0.1 0.038 13.8 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 CCC67547.1 - 0.0022 18.2 0.0 0.0072 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CCC67547.1 - 0.0024 17.3 0.2 0.37 10.1 0.1 2.5 1 1 0 1 1 1 1 AAA-like domain TIP49 PF06068.8 CCC67547.1 - 0.0027 16.4 0.0 0.13 10.9 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_24 PF13479.1 CCC67547.1 - 0.003 17.1 0.0 0.0069 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCC67547.1 - 0.0039 16.3 0.0 0.027 13.6 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 CCC67547.1 - 0.0047 16.4 0.0 0.0084 15.6 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 CCC67547.1 - 0.0051 16.4 0.3 0.11 12.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CCC67547.1 - 0.0074 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 CCC67547.1 - 0.0095 15.8 0.1 0.027 14.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 CCC67547.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CCC67547.1 - 0.03 14.2 0.0 0.059 13.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCC67547.1 - 0.034 14.3 0.0 0.068 13.3 0.0 1.6 1 1 0 1 1 1 0 RNA helicase PhoH PF02562.11 CCC67547.1 - 0.042 13.0 0.0 5.5 6.1 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Arch_ATPase PF01637.13 CCC67547.1 - 0.044 13.4 0.0 0.1 12.3 0.0 1.6 1 1 1 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 CCC67547.1 - 0.057 13.7 0.0 0.24 11.6 0.0 2.1 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 CCC67547.1 - 0.058 12.3 0.1 0.24 10.3 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SNF2_N PF00176.18 CCC67547.1 - 0.16 10.7 0.0 0.98 8.1 0.0 1.9 1 1 0 2 2 2 0 SNF2 family N-terminal domain Mid1 PF12929.2 CCC67548.1 - 8.5e-134 446.4 15.4 1.1e-133 446.0 10.7 1.2 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component TruB_N PF01509.13 CCC67549.1 - 7e-40 136.5 0.3 4.9e-38 130.6 0.0 2.7 3 0 0 3 3 3 1 TruB family pseudouridylate synthase (N terminal domain) Sds3 PF08598.6 CCC67549.1 - 1.5 8.2 13.4 0.12 11.9 5.3 2.1 3 1 0 3 3 3 0 Sds3-like DUF4337 PF14235.1 CCC67549.1 - 5.1 6.9 8.2 9.2 6.0 3.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) RabGAP-TBC PF00566.13 CCC67550.1 - 4.2e-44 150.5 4.3 2.1e-31 109.1 0.0 2.6 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PalH PF08733.5 CCC67551.1 - 2e-86 289.9 16.5 2.7e-86 289.5 11.4 1.2 1 0 0 1 1 1 1 PalH/RIM21 Pet20 PF08692.5 CCC67552.1 - 1.3e-10 41.3 0.4 7.7e-10 38.8 0.0 2.5 2 1 0 2 2 2 1 Mitochondrial protein Pet20 Utp12 PF04003.7 CCC67552.1 - 0.035 13.9 0.2 0.078 12.8 0.1 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family Sec7_N PF12783.2 CCC67553.1 - 2.9e-36 124.4 7.8 2.9e-36 124.4 5.4 4.5 4 1 1 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Pkinase PF00069.20 CCC67554.1 - 6.7e-66 222.0 0.0 1e-65 221.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67554.1 - 2.8e-51 174.0 0.0 4.6e-51 173.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CCC67554.1 - 7.4e-22 77.5 0.3 3.4e-21 75.4 0.2 2.3 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 CCC67554.1 - 4.9e-10 39.5 0.6 1.2e-09 38.2 0.4 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 CCC67554.1 - 8.1e-06 24.9 0.0 1.3e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PH_11 PF15413.1 CCC67554.1 - 0.002 18.3 0.6 0.0045 17.2 0.4 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 CCC67554.1 - 0.012 15.3 0.1 0.032 13.9 0.1 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family NTP_transf_2 PF01909.18 CCC67555.1 - 1.8e-16 60.2 0.8 4.3e-16 59.0 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CCC67555.1 - 5.4e-16 58.2 0.0 2.3e-15 56.2 0.0 2.2 1 0 0 1 1 1 1 Cid1 family poly A polymerase Ribosomal_L18e PF00828.14 CCC67557.1 - 2.6e-24 86.0 0.1 4e-24 85.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Nudc_N PF14050.1 CCC67557.1 - 0.028 14.3 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 N-terminal conserved domain of Nudc. Ribosomal_S19e PF01090.14 CCC67558.1 - 1.7e-54 183.0 0.1 1.8e-54 182.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e RRM_1 PF00076.17 CCC67559.1 - 1.2e-36 124.1 0.4 5e-19 67.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC67559.1 - 3.4e-31 107.0 0.0 1.1e-14 54.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC67559.1 - 1.5e-13 50.3 0.1 3.9e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 CCC67559.1 - 4.6 5.0 18.7 8.3 4.1 13.0 1.3 1 0 0 1 1 1 0 Nop14-like family Ras PF00071.17 CCC67560.1 - 5.4e-28 97.4 0.4 1.8e-22 79.4 0.0 2.2 2 0 0 2 2 2 2 Ras family Miro PF08477.8 CCC67560.1 - 6.2e-12 46.0 0.1 2.2e-07 31.3 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 CCC67560.1 - 1.9e-06 27.2 0.5 0.00015 21.0 0.1 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCC67560.1 - 0.012 15.1 0.1 0.034 13.5 0.0 1.8 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CCC67560.1 - 0.065 12.3 0.1 0.13 11.3 0.1 1.5 1 0 0 1 1 1 0 AIG1 family Bax1-I PF01027.15 CCC67561.1 - 3.3e-37 128.1 23.5 4.5e-37 127.6 16.3 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Orbi_NS3 PF01616.11 CCC67561.1 - 1.1 8.1 3.2 6.7 5.6 0.0 2.5 3 0 0 3 3 3 0 Orbivirus NS3 Ribosomal_L23 PF00276.15 CCC67562.1 - 1.6e-17 63.2 1.2 1.9e-17 62.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L23 Lipoprotein_1 PF00820.14 CCC67562.1 - 0.0096 15.0 0.2 0.011 14.8 0.2 1.0 1 0 0 1 1 1 1 Borrelia lipoprotein Ribosomal_S11 PF00411.14 CCC67563.1 - 2.2e-07 31.0 0.1 4.5e-07 30.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S11 Kri1_C PF12936.2 CCC67564.1 - 7.9e-30 102.6 4.5 7.9e-30 102.6 3.1 5.1 4 1 1 5 5 5 1 KRI1-like family C-terminal Kri1 PF05178.7 CCC67564.1 - 2.4e-17 63.0 20.7 2.4e-17 63.0 14.3 6.2 4 3 0 5 5 5 1 KRI1-like family CorA PF01544.13 CCC67565.1 - 1e-40 139.6 2.0 4.2e-24 85.0 0.0 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein zf-DNL PF05180.7 CCC67567.1 - 1.6e-31 107.8 1.1 2.3e-31 107.2 0.7 1.2 1 0 0 1 1 1 1 DNL zinc finger Elf1 PF05129.8 CCC67567.1 - 0.0061 16.2 0.3 0.011 15.3 0.2 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CSL PF05207.8 CCC67567.1 - 0.036 13.5 0.1 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 CSL zinc finger zinc_ribbon_4 PF13717.1 CCC67567.1 - 1.2 8.9 4.6 6.9 6.4 0.1 2.1 1 1 1 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.13 CCC67567.1 - 1.6 8.4 4.8 15 5.3 3.4 2.1 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) zinc_ribbon_5 PF13719.1 CCC67567.1 - 1.8 8.2 4.7 8.8 6.0 0.1 2.2 1 1 1 2 2 2 0 zinc-ribbon domain F-box-like PF12937.2 CCC67568.1 - 2.5e-06 27.0 0.2 7.6e-06 25.5 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCC67568.1 - 5.7e-06 25.8 0.2 5.7e-06 25.8 0.1 2.4 2 0 0 2 2 2 1 F-box domain HMG_box PF00505.14 CCC67569.1 - 1.6e-15 57.1 0.1 3.4e-15 56.0 0.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCC67569.1 - 2.5e-13 50.1 0.2 1.1e-12 48.1 0.1 2.1 2 0 0 2 2 2 1 HMG-box domain Daxx PF03344.10 CCC67569.1 - 0.037 12.5 27.5 0.05 12.1 19.1 1.2 1 0 0 1 1 1 0 Daxx Family DUF155 PF02582.9 CCC67570.1 - 2.3e-61 206.7 1.4 3.8e-61 206.0 1.0 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 UPF0449 PF15136.1 CCC67570.1 - 0.016 15.3 0.0 0.047 13.8 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF4158 PF13700.1 CCC67570.1 - 0.081 12.4 0.1 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) Histone PF00125.19 CCC67571.1 - 6.5e-26 90.2 0.0 8.8e-26 89.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCC67571.1 - 9.8e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCC67572.1 - 1.3e-21 76.4 0.3 1.8e-21 76.0 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCC67572.1 - 6.9e-06 26.0 0.1 1.3e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CCC67572.1 - 0.0012 19.0 0.0 0.002 18.3 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF77 PF01910.12 CCC67573.1 - 4.7e-28 96.7 0.0 5.4e-28 96.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function DUF77 YugN PF08868.5 CCC67573.1 - 0.015 14.9 0.1 4.7 6.8 0.0 2.1 1 1 1 2 2 2 0 YugN-like family DUF2102 PF09875.4 CCC67573.1 - 0.063 12.7 0.0 0.082 12.4 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2102) AP_endonuc_2 PF01261.19 CCC67573.1 - 0.13 11.4 0.0 0.14 11.4 0.0 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Med2 PF11214.3 CCC67574.1 - 1.5e-30 105.2 8.0 1.5e-30 105.2 5.5 2.3 2 1 0 2 2 2 1 Mediator complex subunit 2 PP2C PF00481.16 CCC67575.1 - 1.8e-73 247.0 0.1 6.1e-73 245.3 0.1 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CCC67575.1 - 0.00058 19.6 0.2 0.0033 17.1 0.2 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) ApoO PF09769.4 CCC67575.1 - 0.19 11.4 0.5 8 6.1 0.4 2.2 1 1 1 2 2 2 0 Apolipoprotein O AAA PF00004.24 CCC67576.1 - 1.3e-40 138.6 0.0 2.2e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCC67576.1 - 5e-07 29.9 0.1 0.0018 18.3 0.1 2.5 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 CCC67576.1 - 1.5e-05 24.0 0.0 2.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 CCC67576.1 - 1.7e-05 24.7 0.0 5.3e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCC67576.1 - 9.3e-05 22.1 0.1 0.00046 19.9 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCC67576.1 - 0.00013 21.9 0.0 0.00064 19.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 CCC67576.1 - 0.00089 18.3 0.0 0.0016 17.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CCC67576.1 - 0.0018 18.2 0.0 0.0039 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCC67576.1 - 0.0032 17.3 0.0 0.0078 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCC67576.1 - 0.0047 17.7 0.4 0.016 16.0 0.1 1.9 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 CCC67576.1 - 0.0072 15.7 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CCC67576.1 - 0.0084 15.8 0.6 0.018 14.8 0.4 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_3 PF07726.6 CCC67576.1 - 0.01 15.4 0.1 0.027 14.0 0.0 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CCC67576.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin NB-ARC PF00931.17 CCC67576.1 - 0.011 14.6 0.0 0.039 12.7 0.0 1.9 2 0 0 2 2 2 0 NB-ARC domain AAA_18 PF13238.1 CCC67576.1 - 0.011 16.0 0.3 0.034 14.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CCC67576.1 - 0.013 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 CCC67576.1 - 0.018 13.7 0.0 0.04 12.6 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 CCC67576.1 - 0.023 14.0 1.0 0.14 11.4 0.2 2.2 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.10 CCC67576.1 - 0.025 14.2 0.1 0.12 12.0 0.0 2.2 2 0 0 2 2 2 0 NTPase PhoH PF02562.11 CCC67576.1 - 0.031 13.4 0.2 0.19 10.9 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein RNA_helicase PF00910.17 CCC67576.1 - 0.039 14.1 0.0 0.086 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 CCC67576.1 - 0.045 13.3 0.2 0.13 11.8 0.1 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CCC67576.1 - 0.05 12.7 0.1 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 CCC67576.1 - 0.064 12.3 0.0 0.39 9.7 0.0 2.1 2 0 0 2 2 2 0 KaiC NACHT PF05729.7 CCC67576.1 - 0.069 12.8 0.2 0.32 10.6 0.1 2.0 2 0 0 2 2 2 0 NACHT domain GalP_UDP_transf PF01087.17 CCC67577.1 - 1.5e-66 223.9 0.2 2.1e-66 223.4 0.2 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CCC67577.1 - 1.4e-65 219.9 0.2 3.8e-65 218.4 0.0 1.8 3 0 0 3 3 3 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 CCC67577.1 - 0.076 13.5 0.1 0.52 10.8 0.0 2.4 3 0 0 3 3 3 0 HIT domain WG_beta_rep PF14903.1 CCC67577.1 - 0.11 12.7 0.1 0.48 10.7 0.1 2.2 1 1 0 1 1 1 0 WG containing repeat GalKase_gal_bdg PF10509.4 CCC67578.1 - 7e-22 76.4 0.0 1.4e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CCC67578.1 - 2.5e-15 56.2 0.1 5.4e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCC67578.1 - 1.5e-11 44.3 0.0 3.4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Transp_cyt_pur PF02133.10 CCC67579.1 - 2.8e-173 576.5 34.6 3.3e-173 576.2 24.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ARD PF03079.9 CCC67579.1 - 0.69 9.8 5.3 0.31 10.9 2.0 1.6 2 0 0 2 2 2 0 ARD/ARD' family Macro PF01661.16 CCC67580.1 - 1.2e-25 89.6 0.0 1.5e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Macro domain Chitin_synth_2 PF03142.10 CCC67581.1 - 1.2e-285 947.9 0.1 1.8e-285 947.3 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 CCC67581.1 - 3.2e-15 56.3 2.6 1.4e-14 54.2 1.8 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCC67581.1 - 5.2e-13 49.3 0.0 5.2e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 CCC67581.1 - 5.6e-06 26.0 0.1 6.7e-05 22.6 0.0 2.5 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glycos_transf_2 PF00535.21 CCC67581.1 - 5.2e-05 22.9 0.0 0.00076 19.2 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 CCC67581.1 - 8.7e-05 21.8 0.0 0.00057 19.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Chitin_synth_1 PF01644.12 CCC67582.1 - 1.2e-78 262.5 1.1 1.8e-78 261.9 0.8 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CCC67582.1 - 1.1e-25 89.0 0.0 2.5e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CCC67582.1 - 5e-23 81.2 5.2 5.1e-19 68.0 0.0 3.1 2 1 1 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CCC67582.1 - 5.9e-11 42.4 1.1 5.9e-11 42.4 0.8 2.5 4 0 0 4 4 4 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCC67582.1 - 1.1e-10 41.7 0.0 9.2e-10 38.7 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 SCO1-SenC PF02630.9 CCC67583.1 - 8.6e-64 214.3 0.6 1.2e-63 213.8 0.0 1.5 2 0 0 2 2 2 1 SCO1/SenC AhpC-TSA PF00578.16 CCC67583.1 - 4.4e-07 29.6 0.0 3e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA family YchF-GTPase_C PF06071.8 CCC67584.1 - 1.8e-37 126.9 0.4 5.1e-37 125.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CCC67584.1 - 2e-12 47.0 0.0 4.1e-12 46.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 CCC67584.1 - 0.00083 19.1 0.0 0.0021 17.8 0.0 1.7 1 0 0 1 1 1 1 TGS domain SecA_PP_bind PF01043.15 CCC67584.1 - 0.0096 16.2 0.1 0.37 11.1 0.0 2.3 2 0 0 2 2 2 1 SecA preprotein cross-linking domain FeoB_N PF02421.13 CCC67584.1 - 0.011 15.0 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B MobB PF03205.9 CCC67584.1 - 0.11 12.1 0.7 6.2 6.5 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 CCC67584.1 - 0.8 9.9 3.4 5.9 7.1 2.3 2.1 1 1 0 1 1 1 0 AAA domain YchF-GTPase_C PF06071.8 CCC67585.1 - 2.5e-37 126.4 0.1 6.4e-37 125.2 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CCC67585.1 - 1.3e-12 47.7 0.0 3.5e-12 46.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 CCC67585.1 - 0.0004 20.1 0.0 0.00097 18.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 CCC67585.1 - 0.0099 15.1 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B SecA_PP_bind PF01043.15 CCC67585.1 - 0.034 14.5 1.1 1 9.7 0.1 2.4 2 0 0 2 2 2 0 SecA preprotein cross-linking domain AAA_23 PF13476.1 CCC67585.1 - 0.069 13.4 0.5 0.23 11.7 0.4 1.9 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 CCC67585.1 - 0.12 12.0 0.6 6.2 6.5 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B ADH_zinc_N PF00107.21 CCC67586.1 - 6.7e-07 28.9 0.0 1.2e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pkinase PF00069.20 CCC67587.1 - 2.5e-66 223.4 0.0 3.9e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67587.1 - 4.4e-32 111.1 0.0 9.2e-32 110.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC67587.1 - 0.0011 17.9 0.0 0.004 16.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 CCC67587.1 - 0.0015 19.0 1.1 0.0015 19.0 0.8 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain CTP_transf_1 PF01148.15 CCC67588.1 - 1.9e-78 263.7 24.8 2.6e-78 263.2 17.2 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family DUF433 PF04255.9 CCC67588.1 - 0.17 11.3 0.1 0.38 10.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF433) SET PF00856.23 CCC67589.1 - 5.5e-06 26.7 0.0 0.0016 18.7 0.0 3.1 2 1 0 2 2 2 1 SET domain Prothymosin PF03247.9 CCC67589.1 - 0.001 19.1 7.2 0.001 19.1 5.0 2.4 2 0 0 2 2 2 1 Prothymosin/parathymosin family DNA_pol_lambd_f PF10391.4 CCC67589.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Nop25 PF09805.4 CCC67589.1 - 0.69 9.9 8.7 1.2 9.2 0.8 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Ribosomal_L4 PF00573.17 CCC67590.1 - 1.1e-46 158.6 2.4 2.3e-46 157.6 1.7 1.5 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 CCC67590.1 - 5.9e-29 99.7 3.4 5.6e-28 96.6 0.4 2.8 2 1 1 3 3 3 1 60S ribosomal protein L4 C-terminal domain ERAP1_C PF11838.3 CCC67590.1 - 0.035 13.3 0.0 0.19 10.9 0.0 2.0 2 0 0 2 2 2 0 ERAP1-like C-terminal domain Methyltransf_31 PF13847.1 CCC67591.1 - 5.1e-14 52.1 0.0 8.6e-14 51.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCC67591.1 - 2.3e-11 43.3 0.0 3.4e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CCC67591.1 - 9.1e-10 39.1 0.0 3.2e-09 37.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCC67591.1 - 1.3e-09 38.1 0.0 2.5e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCC67591.1 - 1.5e-08 34.9 0.0 3.7e-08 33.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCC67591.1 - 3.7e-08 32.4 0.0 4.6e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 CCC67591.1 - 1.1e-07 31.2 0.0 1.4e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.1 CCC67591.1 - 2.3e-07 31.0 0.0 4.9e-06 26.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC67591.1 - 8.6e-07 28.8 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 CCC67591.1 - 4.2e-06 25.9 0.1 5.5e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.9 CCC67591.1 - 1.3e-05 24.6 0.0 2.4e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 CCC67591.1 - 3.7e-05 24.1 0.0 0.00013 22.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 CCC67591.1 - 0.00052 20.0 0.0 0.0014 18.6 0.0 1.6 2 0 0 2 2 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 CCC67591.1 - 0.00053 19.1 0.0 0.00086 18.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 CCC67591.1 - 0.0045 16.4 0.0 0.0069 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_4 PF02390.12 CCC67591.1 - 0.01 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase TehB PF03848.9 CCC67591.1 - 0.015 14.5 0.2 0.039 13.1 0.0 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TehB PCMT PF01135.14 CCC67591.1 - 0.016 14.7 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 CCC67591.1 - 0.019 14.6 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 CCC67591.1 - 0.044 13.3 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.13 CCC67591.1 - 0.064 12.8 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 NNMT_PNMT_TEMT PF01234.12 CCC67591.1 - 0.088 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Sld5 PF05916.6 CCC67592.1 - 1.7e-11 44.3 0.1 2.4e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein CRCB PF02537.10 CCC67594.1 - 1e-30 106.0 25.2 2.8e-21 75.5 5.0 3.0 4 0 0 4 4 4 2 CrcB-like protein DUF4131 PF13567.1 CCC67594.1 - 1.1 8.7 6.9 1.2 8.4 0.4 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF1761 PF08570.5 CCC67594.1 - 1.5 8.8 7.4 0.14 12.1 0.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) DUF46 PF01864.12 CCC67594.1 - 5.6 6.8 9.0 0.21 11.4 0.3 2.4 3 0 0 3 3 3 0 Putative integral membrane protein DUF46 Voldacs PF03517.8 CCC67595.1 - 0.021 14.6 5.5 0.031 14.1 3.8 1.3 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling BSP_II PF05432.6 CCC67595.1 - 0.26 10.5 9.7 0.16 11.2 5.2 1.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Ribosomal_60s PF00428.14 CCC67595.1 - 0.6 10.5 5.9 1.6 9.1 4.1 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DASH_Dad1 PF08649.5 CCC67596.1 - 1.6e-28 98.1 0.3 1.6e-28 98.1 0.2 1.5 2 0 0 2 2 2 1 DASH complex subunit Dad1 GCR1_C PF12550.3 CCC67596.1 - 0.093 12.6 0.2 2.2 8.1 0.0 2.3 1 1 1 2 2 2 0 Transcriptional activator of glycolytic enzymes IPK PF03770.11 CCC67597.1 - 1.5e-49 168.3 2.2 1.5e-49 168.2 0.0 2.2 2 0 0 2 2 2 1 Inositol polyphosphate kinase Acyltransferase PF01553.16 CCC67598.1 - 1.1e-27 96.0 0.1 1.8e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase GCV_T PF01571.16 CCC67599.1 - 2.8e-57 193.5 0.0 3.4e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CCC67599.1 - 4.5e-15 55.4 0.0 7.2e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain TMEM247 PF15444.1 CCC67599.1 - 0.098 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 PRK PF00485.13 CCC67600.1 - 3.2e-09 36.6 0.2 1.1e-06 28.3 0.0 2.1 1 1 1 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 CCC67600.1 - 0.011 16.4 0.4 0.026 15.3 0.3 1.7 1 1 0 1 1 1 0 AAA domain Peptidase_M66 PF10462.4 CCC67600.1 - 0.022 13.6 0.1 0.036 12.9 0.1 1.3 1 0 0 1 1 1 0 Peptidase M66 Spermine_synth PF01564.12 CCC67600.1 - 0.042 12.7 0.0 0.067 12.1 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase Z1 PF10593.4 CCC67600.1 - 0.12 11.5 0.2 0.81 8.8 0.0 2.0 2 0 0 2 2 2 0 Z1 domain DEAD PF00270.24 CCC67601.1 - 1.5e-40 138.4 3.7 1.6e-40 138.3 1.5 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC67601.1 - 7.5e-29 99.4 0.3 4.1e-28 97.0 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 CCC67601.1 - 7.7e-05 22.3 0.2 0.00021 20.9 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CCC67601.1 - 0.00072 19.7 0.2 0.0023 18.0 0.2 1.8 1 1 0 1 1 1 1 AAA domain CMS1 PF14617.1 CCC67601.1 - 0.01 14.9 0.1 0.027 13.5 0.0 1.7 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 CCC67601.1 - 0.02 14.7 0.1 0.038 13.8 0.1 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 CCC67601.1 - 0.021 14.4 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 Helicase AAA_30 PF13604.1 CCC67601.1 - 0.029 13.9 0.1 0.079 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.1 CCC67601.1 - 0.035 14.0 0.2 0.34 10.8 0.0 2.2 1 1 1 2 2 2 0 Helicase C-terminal domain Atg31 PF09795.4 CCC67602.1 - 6.2e-34 117.0 10.2 7.7e-34 116.7 7.1 1.1 1 0 0 1 1 1 1 Autophagy-related protein 31 DUF1524 PF07510.6 CCC67602.1 - 0.096 12.5 0.8 0.19 11.5 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1524) tRNA-synt_2b PF00587.20 CCC67603.1 - 7.4e-35 120.0 0.3 1.6e-34 118.9 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CCC67603.1 - 2.1e-21 75.9 9.9 2.1e-21 75.9 6.9 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain NOD PF06816.8 CCC67603.1 - 0.076 12.1 0.0 0.21 10.7 0.0 1.8 1 0 0 1 1 1 0 NOTCH protein Ribosomal_S17 PF00366.15 CCC67604.1 - 1.7e-29 101.6 5.3 2.7e-29 101.0 3.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Myb_DNA-binding PF00249.26 CCC67605.1 - 1.5e-17 63.3 14.4 1.6e-11 44.0 0.1 4.3 4 1 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCC67605.1 - 4.2e-16 58.8 5.8 6.2e-15 55.0 0.7 5.2 5 1 0 5 5 5 2 Myb-like DNA-binding domain MADF_DNA_bdg PF10545.4 CCC67605.1 - 0.68 10.1 14.5 0.27 11.4 0.3 4.5 4 1 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like DUF1752 PF08550.5 CCC67607.1 - 7e-10 38.3 2.0 1.5e-09 37.2 1.4 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) WD40 PF00400.27 CCC67608.1 - 2.5e-21 74.6 8.2 4.9e-05 23.0 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat SprB PF13573.1 CCC67608.1 - 0.0063 16.0 0.7 0.34 10.5 0.0 2.9 2 0 0 2 2 2 1 SprB repeat FMN_red PF03358.10 CCC67609.1 - 1.4e-10 40.9 0.0 1.8e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 CCC67609.1 - 2.7e-08 33.9 0.1 7.1e-08 32.5 0.1 1.8 2 1 0 2 2 2 1 Flavodoxin Flavodoxin_2 PF02525.12 CCC67609.1 - 2.3e-05 24.0 0.0 2.9e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 CCC67609.1 - 0.15 12.0 0.0 3.2 7.7 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain Dimer_Tnp_hAT PF05699.9 CCC67610.1 - 1e-07 31.4 0.4 7.5e-07 28.6 0.1 2.7 3 0 0 3 3 3 1 hAT family C-terminal dimerisation region Bac_rhodopsin PF01036.13 CCC67611.1 - 1.6e-40 138.7 19.9 2e-40 138.4 13.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein EmrE PF13536.1 CCC67611.1 - 0.051 13.7 0.5 0.051 13.7 0.4 3.1 2 1 1 3 3 3 0 Multidrug resistance efflux transporter PRP1_N PF06424.7 CCC67612.1 - 4.4e-30 104.7 1.1 4.4e-30 104.7 0.8 2.2 2 0 0 2 2 1 1 PRP1 splicing factor, N-terminal TPR_19 PF14559.1 CCC67612.1 - 7.9e-20 70.9 0.0 0.0035 17.6 0.0 7.6 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCC67612.1 - 1.9e-18 65.2 0.0 0.013 16.0 0.0 10.0 9 1 1 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCC67612.1 - 2.2e-13 49.6 5.9 0.00072 19.1 0.0 6.6 6 1 1 7 7 7 3 TPR repeat TPR_2 PF07719.12 CCC67612.1 - 1.4e-12 46.4 4.6 0.014 15.2 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCC67612.1 - 1.1e-09 38.0 0.3 0.54 10.2 0.0 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCC67612.1 - 2e-08 33.4 14.1 0.00083 18.8 0.1 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCC67612.1 - 5.4e-08 33.3 0.0 2.1 9.1 0.0 6.1 6 1 0 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCC67612.1 - 2e-07 30.6 3.0 0.021 15.0 0.0 6.4 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCC67612.1 - 2.5e-06 26.8 13.8 0.0031 17.1 0.1 7.6 8 0 0 8 8 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CCC67612.1 - 2.9e-06 27.3 9.3 0.025 14.7 0.1 5.1 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCC67612.1 - 1.3e-05 25.2 14.0 0.054 13.9 0.0 7.1 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCC67612.1 - 0.022 14.5 5.7 3.6 7.6 0.0 5.6 7 0 0 7 7 5 0 Tetratricopeptide repeat DUF4608 PF15381.1 CCC67612.1 - 0.13 12.4 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4608) Fungal_trans_2 PF11951.3 CCC67613.1 - 1.9e-22 79.4 2.5 2.9e-22 78.8 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC67613.1 - 1.4e-06 28.0 11.1 3.1e-06 26.9 7.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DAHP_synth_1 PF00793.15 CCC67614.1 - 1e-101 339.2 0.0 1.2e-101 338.9 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family Mst1_SARAH PF11629.3 CCC67615.1 - 0.054 13.3 0.8 0.054 13.3 0.5 3.4 2 1 1 3 3 3 0 C terminal SARAH domain of Mst1 IKKbetaNEMObind PF12179.3 CCC67615.1 - 2.9 7.7 10.9 4.2 7.2 0.2 3.8 4 0 0 4 4 4 0 I-kappa-kinase-beta NEMO binding domain SlyX PF04102.7 CCC67615.1 - 4.5 7.7 14.1 3.6 8.0 0.3 3.3 3 0 0 3 3 3 0 SlyX DUF972 PF06156.8 CCC67615.1 - 10 6.5 15.6 6.4 7.1 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF972) ECH PF00378.15 CCC67616.1 - 3.8e-31 108.0 0.1 2.7e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 CCC67616.1 - 2.6e-21 75.9 0.2 6.5e-21 74.6 0.1 1.7 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Pkinase PF00069.20 CCC67617.1 - 1.8e-36 125.6 0.2 1.8e-36 125.6 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67617.1 - 7.1e-26 90.8 0.0 1.9e-25 89.3 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCC67617.1 - 0.00018 21.2 0.0 0.055 13.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family tRNA-synt_2 PF00152.15 CCC67618.1 - 2.1e-87 293.0 0.9 2.1e-87 293.0 0.6 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCC67618.1 - 1.1e-11 44.3 0.1 2.4e-11 43.3 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 CCC67618.1 - 1.8e-07 30.6 0.0 0.0015 17.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUP PF00674.13 CCC67619.1 - 6.6e-16 58.2 3.2 6.6e-16 58.2 2.2 2.1 2 1 0 2 2 2 1 DUP family E1-E2_ATPase PF00122.15 CCC67620.1 - 9.6e-68 227.6 4.1 2.2e-67 226.4 2.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCC67620.1 - 2.3e-32 112.0 3.0 2.3e-32 112.0 2.1 2.8 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCC67620.1 - 4.7e-26 92.5 0.0 6e-25 88.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCC67620.1 - 2.3e-17 62.7 0.0 4.4e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCC67620.1 - 3.5e-13 50.1 0.0 1.2e-12 48.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCC67620.1 - 2.5e-10 39.6 0.0 2.5e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCC67620.1 - 0.00081 19.0 3.2 0.0014 18.2 0.8 2.3 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Ribosomal_S10 PF00338.17 CCC67621.1 - 1.4e-28 98.5 0.0 2.3e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Pkr1 PF08636.5 CCC67622.1 - 0.83 9.7 3.9 1.6 8.8 2.7 1.5 1 0 0 1 1 1 0 ER protein Pkr1 zf-C2H2 PF00096.21 CCC67623.1 - 0.00014 22.0 1.0 0.00014 22.0 0.7 3.4 3 0 0 3 3 3 1 Zinc finger, C2H2 type DUF2011 PF09428.5 CCC67623.1 - 0.00088 19.1 0.3 0.0012 18.6 0.2 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) zf-H2C2_2 PF13465.1 CCC67623.1 - 0.0015 18.7 5.4 0.0015 18.7 3.7 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC67623.1 - 0.0027 17.9 19.1 0.0046 17.1 0.1 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 CCC67623.1 - 0.032 14.4 0.4 0.032 14.4 0.3 2.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type RPAP2_Rtr1 PF04181.8 CCC67623.1 - 0.65 10.1 4.0 2.1 8.4 0.2 2.3 2 0 0 2 2 2 0 Rtr1/RPAP2 family IBB PF01749.15 CCC67623.1 - 4.5 7.4 8.5 0.5 10.5 2.5 1.8 2 0 0 2 2 2 0 Importin beta binding domain Coprogen_oxidas PF01218.13 CCC67624.1 - 7.3e-133 441.6 0.0 8.3e-133 441.4 0.0 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase TFIIS_C PF01096.13 CCC67625.1 - 1.1e-21 76.1 2.1 1.1e-21 76.1 1.5 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 CCC67625.1 - 3.6e-15 55.3 2.0 3.7e-15 55.3 0.2 1.9 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 CCC67625.1 - 0.0041 16.8 4.1 0.13 12.0 0.5 2.4 2 0 0 2 2 2 2 Transposase zinc-ribbon domain PhnA_Zn_Ribbon PF08274.7 CCC67625.1 - 0.013 15.2 7.4 0.089 12.5 0.3 3.1 3 0 0 3 3 3 0 PhnA Zinc-Ribbon Elf1 PF05129.8 CCC67625.1 - 0.045 13.4 3.2 0.21 11.2 0.0 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like DUF2387 PF09526.5 CCC67625.1 - 0.16 11.8 2.9 2.7 7.9 0.1 2.3 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Baculo_LEF5_C PF11792.3 CCC67625.1 - 1.2 8.5 4.4 0.46 9.8 0.1 2.4 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain DZR PF12773.2 CCC67625.1 - 1.5 8.7 5.2 2.9 7.7 0.1 2.6 2 1 0 2 2 2 0 Double zinc ribbon zf-piccolo PF05715.8 CCC67625.1 - 1.5 8.8 7.0 0.17 11.8 0.6 2.3 3 0 0 3 3 3 0 Piccolo Zn-finger AA_permease PF00324.16 CCC67626.1 - 3.3e-131 437.9 32.3 4.1e-131 437.6 22.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC67626.1 - 5.2e-37 127.3 31.5 6.9e-37 126.9 21.8 1.1 1 0 0 1 1 1 1 Amino acid permease URO-D PF01208.12 CCC67627.1 - 1.1e-121 405.9 0.0 1.2e-121 405.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ank_2 PF12796.2 CCC67628.1 - 0.00084 19.6 0.0 0.0019 18.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 CCC67628.1 - 0.002 17.8 0.1 0.0085 15.8 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 CCC67628.1 - 0.017 15.3 0.0 0.045 14.0 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCC67628.1 - 0.052 13.8 0.0 0.19 12.0 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.1 CCC67628.1 - 0.091 13.3 0.0 0.36 11.3 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) HSP20 PF00011.16 CCC67629.1 - 1.7e-21 76.0 2.2 2.2e-21 75.6 1.5 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Homeobox_KN PF05920.6 CCC67629.1 - 0.062 13.0 0.0 0.16 11.6 0.0 1.8 1 0 0 1 1 1 0 Homeobox KN domain DUF3835 PF12927.2 CCC67629.1 - 0.097 13.6 0.1 2.3 9.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3835) Alg14 PF08660.6 CCC67631.1 - 5.6e-52 176.1 0.2 8.4e-52 175.5 0.2 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like TIM PF00121.13 CCC67632.1 - 5.3e-89 297.4 0.1 5.9e-89 297.3 0.1 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase His_Phos_1 PF00300.17 CCC67633.1 - 1.4e-37 129.1 0.0 3.2e-37 128.0 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Dfp1_Him1_M PF08630.5 CCC67634.1 - 3.3e-44 149.6 0.2 8.8e-44 148.2 0.1 1.8 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 CCC67634.1 - 3.2e-20 71.5 1.3 6.2e-20 70.6 0.9 1.4 1 0 0 1 1 1 1 DBF zinc finger HHH_8 PF14716.1 CCC67634.1 - 0.037 14.2 0.0 0.093 12.9 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain LMBR1 PF04791.11 CCC67634.1 - 0.06 11.9 2.2 0.076 11.5 1.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein UQ_con PF00179.21 CCC67635.1 - 1.3e-44 150.9 0.0 1.7e-44 150.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCC67635.1 - 0.012 15.3 0.0 0.044 13.5 0.0 1.9 1 1 0 1 1 1 0 Prokaryotic E2 family B AMNp_N PF10423.4 CCC67635.1 - 0.014 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus NOA36 PF06524.7 CCC67635.1 - 1.1 8.5 10.5 1.4 8.1 7.3 1.1 1 0 0 1 1 1 0 NOA36 protein Recep_L_domain PF01030.19 CCC67636.1 - 3.9e-10 39.6 13.8 0.004 17.1 0.1 5.3 1 1 4 5 5 5 5 Receptor L domain LRR_9 PF14580.1 CCC67636.1 - 0.0017 17.9 0.1 0.0049 16.4 0.1 1.7 1 1 0 1 1 1 1 Leucine-rich repeat Ecm33 PF12454.3 CCC67636.1 - 9.7 6.1 14.1 0.64 9.9 2.4 3.4 4 0 0 4 4 4 0 GPI-anchored cell wall organization protein PRKCSH PF07915.8 CCC67637.1 - 3.3e-08 34.2 0.9 3.3e-08 34.2 0.6 4.0 3 1 0 3 3 3 1 Glucosidase II beta subunit-like protein UQ_con PF00179.21 CCC67638.1 - 3.7e-51 172.2 0.0 4.1e-51 172.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCC67638.1 - 4.5e-05 23.2 0.0 5.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCC67638.1 - 0.00024 20.9 0.0 0.00027 20.8 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 CCC67638.1 - 0.0048 16.5 0.0 0.0082 15.8 0.0 1.3 1 0 0 1 1 1 1 UEV domain Gp_dh_C PF02800.15 CCC67639.1 - 1.1e-73 245.9 0.1 1.8e-73 245.1 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CCC67639.1 - 1.6e-58 196.9 0.5 2.8e-58 196.1 0.1 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CCC67639.1 - 0.0078 16.1 0.2 0.03 14.2 0.1 2.1 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus TEA PF01285.13 CCC67640.1 - 9.7e-33 113.9 0.3 9.7e-33 113.9 0.2 2.0 2 1 0 2 2 2 1 TEA/ATTS domain family Phage_int_SAM_5 PF13102.1 CCC67640.1 - 0.3 11.0 3.1 1.1 9.2 2.2 1.9 1 1 0 1 1 1 0 Phage integrase SAM-like domain Ribosomal_L19e PF01280.15 CCC67641.1 - 4.2e-58 195.3 9.1 4.2e-58 195.3 6.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e DUF2423 PF10338.4 CCC67642.1 - 6.3e-20 70.8 5.0 6.3e-20 70.8 3.4 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) DUF4632 PF15451.1 CCC67642.1 - 0.069 13.0 0.3 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) DUF2984 PF11203.3 CCC67642.1 - 0.14 12.2 0.4 0.26 11.4 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2984) ECM11 PF15463.1 CCC67642.1 - 0.82 9.9 6.4 0.19 12.0 1.2 1.9 1 1 1 2 2 2 0 Extracellular mutant protein 11 Spore_III_AF PF09581.5 CCC67642.1 - 2.4 7.9 7.1 3.6 7.4 4.9 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) Vfa1 PF08432.5 CCC67642.1 - 6.2 6.8 11.3 7.4 6.5 7.8 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Dimer_Tnp_hAT PF05699.9 CCC67644.1 - 8.1e-09 34.9 0.2 3e-08 33.1 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 CCC67644.1 - 0.023 14.4 0.6 0.052 13.3 0.4 1.7 1 0 0 1 1 1 0 BED zinc finger Cys_rich_CPCC PF14206.1 CCC67645.1 - 0.028 13.9 2.4 0.069 12.7 0.2 2.1 2 0 0 2 2 2 0 Cysteine-rich CPCC zf-Mss51 PF13824.1 CCC67645.1 - 0.033 14.0 3.6 3.7 7.4 0.5 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-CHY PF05495.7 CCC67645.1 - 0.035 14.2 0.1 2.2 8.4 0.0 2.1 2 0 0 2 2 2 0 CHY zinc finger TF_Zn_Ribbon PF08271.7 CCC67645.1 - 0.055 12.8 1.0 1.7 8.0 0.1 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding Zn_Tnp_IS1 PF03811.8 CCC67645.1 - 0.076 12.5 1.9 5.8 6.4 0.1 2.2 2 0 0 2 2 2 0 InsA N-terminal domain Cys_rich_KTR PF14205.1 CCC67645.1 - 0.085 12.3 0.7 6.4 6.3 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich KTR RecR PF02132.10 CCC67645.1 - 0.12 11.8 3.0 0.53 9.7 0.1 2.2 2 0 0 2 2 2 0 RecR protein Zn_Tnp_IS1595 PF12760.2 CCC67645.1 - 0.13 12.0 4.2 1.9 8.3 0.2 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 CCC67645.1 - 0.24 10.6 2.8 0.7 9.1 0.4 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.7 CCC67645.1 - 0.84 9.4 2.8 12 5.7 0.2 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Mito_carr PF00153.22 CCC67646.1 - 1.7e-68 226.3 7.5 3.7e-24 84.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PsbX PF06596.6 CCC67646.1 - 0.28 10.8 1.2 1 9.0 0.9 2.0 1 0 0 1 1 1 0 Photosystem II reaction centre X protein (PsbX) DUF3719 PF12516.3 CCC67647.1 - 0.015 14.8 0.0 0.097 12.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3719) KH_1 PF00013.24 CCC67648.1 - 2.2e-33 113.6 9.7 3.8e-12 45.6 0.2 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCC67648.1 - 6.2e-25 86.3 11.6 6.5e-09 35.2 0.1 3.5 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CCC67648.1 - 7.1e-05 22.3 1.4 2 8.1 0.0 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CCC67648.1 - 0.00014 21.3 12.0 0.19 11.3 0.1 4.0 3 1 0 3 3 3 3 KH domain KH_5 PF13184.1 CCC67648.1 - 0.015 15.1 8.5 1.8 8.4 0.2 3.6 3 1 0 3 3 3 0 NusA-like KH domain CENP-B_dimeris PF09026.5 CCC67648.1 - 0.051 13.8 0.3 0.22 11.7 0.0 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GTP_cyclohydro2 PF00925.15 CCC67649.1 - 1.2e-56 190.5 0.0 1.3e-51 174.2 0.0 2.2 2 0 0 2 2 2 2 GTP cyclohydrolase II CLASP_N PF12348.3 CCC67650.1 - 1.7e-64 217.3 14.8 9e-62 208.3 6.8 4.3 4 1 1 5 5 5 2 CLASP N terminal Pol_alpha_B_N PF08418.5 CCC67651.1 - 1.8e-67 227.5 13.0 2.5e-67 227.0 9.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 CCC67651.1 - 5.1e-48 163.1 0.4 8.9e-48 162.3 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B CDC48_N PF02359.13 CCC67651.1 - 0.072 13.0 0.0 0.38 10.7 0.0 2.1 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Anoctamin PF04547.7 CCC67652.1 - 8.4e-34 116.9 23.7 2e-32 112.4 16.4 2.2 1 1 0 1 1 1 1 Calcium-activated chloride channel Adaptin_N PF01602.15 CCC67653.1 - 5.7e-108 361.5 24.8 6.8e-108 361.2 17.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 CCC67653.1 - 1.2e-07 32.0 3.5 1.2e-07 32.0 0.1 2.6 2 0 0 2 2 2 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.11 CCC67653.1 - 1.3e-05 25.0 0.2 6.3e-05 22.8 0.1 2.3 1 1 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain HEAT_2 PF13646.1 CCC67653.1 - 0.014 15.6 0.1 5 7.4 0.1 3.6 2 1 1 3 3 3 0 HEAT repeats HEAT PF02985.17 CCC67653.1 - 0.024 14.6 1.3 0.78 9.9 0.1 3.8 5 0 0 5 5 5 0 HEAT repeat Rep_fac_C PF08542.6 CCC67654.1 - 3.5e-19 68.5 1.3 1e-18 67.0 0.3 2.2 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 CCC67654.1 - 2e-12 47.0 0.1 8.3e-12 45.0 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 CCC67654.1 - 8.5e-07 29.2 0.0 2.1e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CCC67654.1 - 0.00033 19.4 1.1 0.029 13.0 0.0 2.5 2 1 1 3 3 3 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CCC67654.1 - 0.0022 17.9 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Orbi_VP2 PF00898.12 CCC67654.1 - 0.0052 14.3 0.2 0.0066 14.0 0.2 1.1 1 0 0 1 1 1 1 Orbivirus outer capsid protein VP2 AAA_10 PF12846.2 CCC67654.1 - 0.011 15.2 0.1 0.046 13.1 0.1 1.8 1 1 0 1 1 1 0 AAA-like domain Sigma54_activ_2 PF14532.1 CCC67654.1 - 0.014 15.4 0.1 2 8.4 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_22 PF13401.1 CCC67654.1 - 0.027 14.6 0.3 0.22 11.6 0.1 2.5 2 1 0 2 2 2 0 AAA domain NYD-SP12_N PF15015.1 CCC67654.1 - 0.035 12.3 0.1 0.051 11.8 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Transglut_C PF00927.17 CCC67654.1 - 0.057 13.4 0.0 0.56 10.2 0.0 2.4 2 1 0 2 2 2 0 Transglutaminase family, C-terminal ig like domain RuvB_N PF05496.7 CCC67654.1 - 0.083 11.9 0.1 0.76 8.7 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Ribosomal_L16 PF00252.13 CCC67655.1 - 2e-34 118.2 0.1 3e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e tRNA-synt_2d PF01409.15 CCC67656.1 - 1e-48 165.7 0.3 7e-26 90.9 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 CCC67656.1 - 2.4e-25 88.4 0.2 1.3e-24 86.1 0.0 2.2 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 CCC67656.1 - 0.068 11.9 3.9 2.7 6.6 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetases class II (D, K and N) ATG11 PF10377.4 CCC67657.1 - 1.1e-34 119.0 0.0 1.1e-34 119.0 0.0 2.6 2 0 0 2 2 2 1 Autophagy-related protein 11 Acetyltransf_1 PF00583.19 CCC67658.1 - 1.8e-17 63.1 0.0 2.7e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCC67658.1 - 2.8e-09 37.0 0.0 4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCC67658.1 - 2.3e-08 34.0 0.0 2.8e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCC67658.1 - 3.7e-08 32.9 0.1 5.6e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCC67658.1 - 4e-07 30.1 0.0 5.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 CCC67658.1 - 3.9e-06 27.0 0.0 4.7e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCC67658.1 - 0.00021 21.1 0.0 0.00052 19.8 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCC67658.1 - 0.0012 18.6 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 CCC67658.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase HMG_box PF00505.14 CCC67659.1 - 3e-25 88.2 2.1 4.7e-25 87.6 1.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCC67659.1 - 1.2e-19 70.4 1.8 2e-19 69.7 1.3 1.3 1 0 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 CCC67659.1 - 0.0032 17.6 2.6 0.013 15.6 0.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) HMG_box_5 PF14887.1 CCC67659.1 - 0.0059 16.3 2.4 0.011 15.5 1.7 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box 5 CHDNT PF08073.7 CCC67659.1 - 0.02 14.5 0.0 0.032 13.9 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain YABBY PF04690.8 CCC67659.1 - 0.067 13.4 0.4 0.067 13.4 0.3 1.6 1 1 1 2 2 2 0 YABBY protein Pkinase PF00069.20 CCC67660.1 - 5.8e-62 209.1 0.1 7.1e-62 208.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67660.1 - 3.2e-30 105.0 0.0 4.6e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 CCC67660.1 - 0.013 14.3 0.1 0.027 13.3 0.0 1.5 1 0 0 1 1 1 0 Seadornavirus VP7 Sec8_exocyst PF04048.9 CCC67661.1 - 4.6e-45 152.7 4.5 4.6e-45 152.7 3.1 2.6 2 1 1 3 3 3 1 Sec8 exocyst complex component specific domain Sec5 PF15469.1 CCC67661.1 - 7.3e-09 35.5 13.1 7.3e-09 35.5 9.1 3.4 3 1 1 4 4 4 1 Exocyst complex component Sec5 Phage_term_sma PF07141.6 CCC67661.1 - 0.041 13.4 1.5 0.11 12.0 0.3 2.2 2 0 0 2 2 2 0 Putative bacteriophage terminase small subunit Tfb4 PF03850.9 CCC67662.1 - 1.1e-103 346.3 0.2 1.3e-103 346.1 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 VWA_2 PF13519.1 CCC67662.1 - 0.0014 18.7 0.0 0.0021 18.1 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain SIP1 PF04938.7 CCC67663.1 - 0.00014 21.3 0.8 0.00082 18.8 0.1 2.4 2 1 0 2 2 2 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) Mito_carr PF00153.22 CCC67664.1 - 2.3e-60 200.3 1.8 2.6e-21 75.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein CM_2 PF01817.16 CCC67665.1 - 1.9e-11 43.8 0.0 8.6e-06 25.7 0.0 3.7 2 1 0 2 2 2 2 Chorismate mutase type II DnaJ PF00226.26 CCC67666.1 - 1.7e-10 40.4 1.3 3.7e-10 39.3 0.9 1.6 1 0 0 1 1 1 1 DnaJ domain dCMP_cyt_deam_1 PF00383.17 CCC67667.1 - 1.7e-22 78.9 0.0 2.2e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 CCC67667.1 - 0.00041 20.2 0.1 0.00077 19.3 0.0 1.5 1 1 0 1 1 1 1 Bd3614-like deaminase XOO_2897-deam PF14440.1 CCC67667.1 - 0.04 13.6 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Xanthomonas XOO_2897-like deaminase UPF0139 PF03669.8 CCC67668.1 - 0.0036 16.7 0.6 0.014 14.8 0.1 1.9 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0139) Vac_ImportDeg PF09783.4 CCC67669.1 - 1.1e-45 155.2 0.1 1.6e-45 154.7 0.1 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein HMG_box PF00505.14 CCC67670.1 - 4.9e-17 61.9 2.2 4.9e-17 61.9 1.5 2.0 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCC67670.1 - 3.6e-08 33.6 0.5 3.6e-08 33.6 0.3 1.8 2 0 0 2 2 2 1 HMG-box domain MRP-S24 PF14955.1 CCC67670.1 - 0.015 15.1 0.2 0.028 14.2 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ribosome subunit S24 Pho88 PF10032.4 CCC67671.1 - 3.1e-76 254.8 0.4 3.5e-76 254.7 0.3 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) ThiF PF00899.16 CCC67672.1 - 4.6e-31 107.4 0.0 8.1e-31 106.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CCC67672.1 - 4.5e-17 61.3 0.2 1.6e-16 59.6 0.0 1.9 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCC67672.1 - 1.8e-08 33.6 1.3 4.1e-08 32.4 0.9 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 CCC67672.1 - 0.0004 20.4 0.1 0.00069 19.7 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 CCC67672.1 - 0.07 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fe-S_biosyn PF01521.15 CCC67673.1 - 1.2e-12 47.7 0.1 3.3e-05 23.7 0.0 2.2 1 1 1 2 2 2 2 Iron-sulphur cluster biosynthesis Adhesin_Dr PF04619.7 CCC67673.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Dr-family adhesin EF-hand_1 PF00036.27 CCC67675.1 - 2e-29 98.6 8.3 1.4e-08 33.4 0.0 4.6 4 1 1 5 5 5 4 EF hand EF-hand_7 PF13499.1 CCC67675.1 - 7.8e-28 96.4 3.2 6.8e-15 54.9 0.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCC67675.1 - 9.9e-25 84.1 5.8 6.1e-08 31.9 0.0 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.1 CCC67675.1 - 4.7e-19 67.7 4.0 1.7e-10 40.3 0.0 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CCC67675.1 - 9.8e-17 59.4 11.5 5.8e-08 31.7 0.1 5.0 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.1 CCC67675.1 - 2.7e-13 49.5 0.1 1.1e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CCC67675.1 - 2.3e-07 30.8 0.2 0.00047 20.1 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CCC67675.1 - 0.00048 19.7 0.0 1.5 8.5 0.0 2.6 2 1 0 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_4 PF12763.2 CCC67675.1 - 0.0032 17.1 0.5 0.0093 15.6 0.1 1.8 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Caleosin PF05042.8 CCC67675.1 - 0.0055 16.2 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 2 Caleosin related protein DUF853 PF05872.7 CCC67675.1 - 0.033 12.5 0.1 0.064 11.5 0.1 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TerB PF05099.8 CCC67675.1 - 0.038 13.7 0.2 0.82 9.3 0.0 2.1 1 1 0 2 2 2 0 Tellurite resistance protein TerB H-kinase_dim PF02895.9 CCC67675.1 - 0.071 13.4 0.6 1.7 9.0 0.1 2.7 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain DUF4373 PF14297.1 CCC67675.1 - 0.13 12.5 0.2 0.63 10.3 0.0 2.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4373) RNA_pol_Rpb4 PF03874.11 CCC67675.1 - 0.24 11.4 1.5 2 8.4 0.2 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 Hist_deacetyl PF00850.14 CCC67676.1 - 6.5e-69 232.6 0.0 9.4e-69 232.0 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Med1 PF10744.4 CCC67677.1 - 3.6e-66 223.5 12.2 3.1e-65 220.4 4.9 2.4 2 1 0 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 TPR_1 PF00515.23 CCC67678.1 - 6.1e-52 171.2 20.0 1.6e-07 30.5 0.0 10.9 10 1 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 CCC67678.1 - 7.2e-46 153.7 22.2 3.4e-11 42.6 0.5 6.4 2 2 4 7 7 7 7 TPR repeat TPR_2 PF07719.12 CCC67678.1 - 5.5e-45 147.7 22.5 8.6e-05 22.1 0.0 10.2 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_17 PF13431.1 CCC67678.1 - 5e-33 110.5 21.5 0.00013 21.9 0.1 11.3 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_12 PF13424.1 CCC67678.1 - 2.8e-29 100.8 27.3 4.3e-08 32.9 0.1 7.4 3 2 5 8 8 8 8 Tetratricopeptide repeat TPR_14 PF13428.1 CCC67678.1 - 1.9e-28 96.3 17.0 7.2e-05 23.0 0.1 10.3 2 2 8 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 CCC67678.1 - 4.2e-28 97.3 18.1 8.3e-06 26.3 1.0 7.1 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.1 CCC67678.1 - 2.2e-27 92.7 18.6 0.046 13.5 0.1 10.6 8 2 2 10 10 10 8 Tetratricopeptide repeat TPR_19 PF14559.1 CCC67678.1 - 1e-23 83.3 14.3 5.4e-06 26.6 0.2 7.6 4 3 2 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.1 CCC67678.1 - 1.8e-19 67.8 22.8 0.00045 19.8 0.2 9.9 9 1 1 10 10 10 5 Tetratricopeptide repeat TPR_9 PF13371.1 CCC67678.1 - 2.7e-17 62.3 12.0 3.7e-05 23.4 0.0 6.2 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.1 CCC67678.1 - 4.7e-15 54.9 14.4 0.35 11.4 0.0 9.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_15 PF13429.1 CCC67678.1 - 1.5e-06 27.4 30.4 0.0067 15.5 0.1 5.1 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 CCC67678.1 - 0.012 15.5 16.2 0.49 10.4 0.3 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat SDH_alpha PF03313.10 CCC67678.1 - 0.41 9.6 9.9 0.5 9.3 2.5 2.7 2 1 0 2 2 2 0 Serine dehydratase alpha chain Not3 PF04065.10 CCC67679.1 - 3.1e-77 258.9 35.6 3.1e-77 258.9 24.7 3.6 3 1 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CCC67679.1 - 1.1e-24 86.8 6.9 1.1e-24 86.8 4.8 4.7 3 2 1 4 4 4 1 NOT2 / NOT3 / NOT5 family LMWPc PF01451.16 CCC67680.1 - 4.8e-40 137.0 0.0 5.5e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Transketolase_N PF00456.16 CCC67681.1 - 2.2e-155 516.5 0.0 9.6e-155 514.4 0.0 1.8 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CCC67681.1 - 1.4e-48 164.6 0.0 2.4e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCC67681.1 - 3.1e-14 52.9 0.0 7.6e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.15 CCC67681.1 - 0.0001 21.1 0.0 0.00041 19.1 0.0 1.8 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CCC67681.1 - 0.00048 19.1 0.0 0.0048 15.8 0.0 2.2 1 1 1 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Opy2 PF09463.5 CCC67682.1 - 1.3e-09 37.9 20.0 1.9e-09 37.4 13.9 1.3 1 0 0 1 1 1 1 Opy2 protein Herpes_gE PF02480.11 CCC67682.1 - 0.00052 18.4 0.0 0.00095 17.5 0.0 1.5 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E YL1 PF05764.8 CCC67682.1 - 0.22 11.1 12.6 0.035 13.7 5.9 1.6 1 1 1 2 2 2 0 YL1 nuclear protein Gly-zipper_Omp PF13488.1 CCC67682.1 - 0.53 9.9 8.9 0.94 9.1 6.2 1.3 1 0 0 1 1 1 0 Glycine zipper DUF4581 PF15167.1 CCC67682.1 - 1.4 8.7 5.0 3.4 7.5 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4581) GTP_EFTU PF00009.22 CCC67684.1 - 2e-57 193.6 0.0 2.8e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCC67684.1 - 1.5e-35 121.3 0.0 4.3e-35 119.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCC67684.1 - 3e-17 62.4 2.1 3e-17 62.4 1.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCC67684.1 - 2e-05 24.1 0.6 2e-05 24.1 0.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCC67684.1 - 0.0012 18.7 0.2 0.0036 17.2 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DIM1 PF02966.11 CCC67685.1 - 2.8e-68 227.5 0.6 3.1e-68 227.3 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 CCC67685.1 - 0.00096 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DUF3192 PF11399.3 CCC67685.1 - 0.071 13.0 0.1 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Glyco_transf_20 PF00982.16 CCC67686.1 - 2.1e-201 669.5 0.0 2.4e-201 669.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 CCC67686.1 - 6e-05 22.5 0.5 0.015 14.7 0.1 2.8 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCC67686.1 - 0.005 17.0 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CCC67686.1 - 0.041 14.1 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 PUB PF09409.5 CCC67687.1 - 0.12 12.1 4.1 0.23 11.2 0.3 2.9 2 1 0 2 2 2 0 PUB domain Synaptonemal_3 PF15191.1 CCC67687.1 - 0.13 12.0 1.8 15 5.4 0.1 3.3 1 1 2 3 3 3 0 Synaptonemal complex central element protein 3 Ras PF00071.17 CCC67688.1 - 9.8e-05 21.8 0.0 0.43 9.9 0.0 2.7 3 0 0 3 3 3 2 Ras family Miro PF08477.8 CCC67688.1 - 0.0052 17.2 0.0 0.041 14.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 CCC67688.1 - 0.0063 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain WD40 PF00400.27 CCC67689.1 - 1.7e-05 24.5 0.2 0.00055 19.7 0.0 3.1 3 0 0 3 3 3 1 WD domain, G-beta repeat DIL PF01843.14 CCC67691.1 - 1.5e-10 40.8 11.8 3.4e-05 23.6 0.7 3.8 3 1 1 4 4 4 2 DIL domain Ank_2 PF12796.2 CCC67691.1 - 1.7e-06 28.3 0.1 6.7e-06 26.3 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCC67691.1 - 0.00022 21.6 1.2 0.077 13.5 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCC67691.1 - 0.0017 18.5 0.4 0.44 10.8 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) DUF2404 PF10296.4 CCC67692.1 - 8.3e-31 105.9 0.2 1.6e-30 105.0 0.1 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 CCC67692.1 - 1.2e-10 41.5 2.7 3.4e-10 40.0 1.9 1.9 1 1 0 1 1 1 1 PH domain PH_11 PF15413.1 CCC67692.1 - 0.00046 20.4 1.5 0.001 19.2 0.2 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain zf-RING_2 PF13639.1 CCC67693.1 - 1e-13 50.8 19.4 2.5e-10 39.9 3.1 2.5 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4 PF00097.20 CCC67693.1 - 8.4e-09 34.9 3.8 8.4e-09 34.9 2.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC67693.1 - 1.9e-06 27.7 4.2 1.9e-06 27.7 2.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCC67693.1 - 5.3e-06 26.4 16.3 1.1e-05 25.4 3.2 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 CCC67693.1 - 0.00025 20.7 6.6 0.00025 20.7 4.6 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 CCC67693.1 - 0.00027 20.6 3.9 0.00027 20.6 2.7 2.6 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CCC67693.1 - 0.00032 20.2 4.4 0.00032 20.2 3.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 CCC67693.1 - 0.0017 18.0 1.5 0.0017 18.0 1.0 2.9 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 CCC67693.1 - 0.0091 15.6 5.7 0.0091 15.6 4.0 2.9 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.1 CCC67693.1 - 0.016 14.8 19.1 0.021 14.5 1.5 3.6 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 Plasmid_Txe PF06769.8 CCC67693.1 - 0.079 12.7 0.6 5.9 6.7 0.1 2.5 2 0 0 2 2 2 0 Plasmid encoded toxin Txe Peptidase_C74 PF12387.3 CCC67693.1 - 0.21 10.7 1.6 22 4.1 0.0 3.0 3 0 0 3 3 3 0 Pestivirus NS2 peptidase zf-RING-like PF08746.6 CCC67693.1 - 0.45 10.5 20.0 1.3 9.0 3.8 3.0 2 1 0 2 2 2 0 RING-like domain zf-Nse PF11789.3 CCC67693.1 - 0.48 9.9 10.6 1.3 8.5 1.6 2.6 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 CCC67693.1 - 1.9 8.4 12.8 0.28 11.0 2.0 3.3 2 2 1 3 3 3 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 CCC67693.1 - 2.1 8.4 18.0 0.079 13.0 2.2 2.6 2 0 0 2 2 2 0 RING-variant domain FANCL_C PF11793.3 CCC67693.1 - 2.6 8.0 19.1 2.9 7.9 3.7 3.0 2 2 0 2 2 2 0 FANCL C-terminal domain PHF5 PF03660.9 CCC67694.1 - 3.3e-49 165.3 13.4 3.8e-49 165.2 9.3 1.0 1 0 0 1 1 1 1 PHF5-like protein Sec7 PF01369.15 CCC67695.1 - 3.3e-33 114.9 0.8 3.3e-33 114.9 0.5 1.9 2 0 0 2 2 2 1 Sec7 domain DUF3818 PF12825.2 CCC67696.1 - 4.8e-128 426.6 13.4 4.8e-128 426.6 9.3 2.9 4 1 1 5 5 5 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 CCC67696.1 - 3.5e-47 159.4 3.4 3.5e-47 159.4 2.3 2.7 3 0 0 3 3 3 1 PX-associated PX PF00787.19 CCC67696.1 - 5.3e-09 35.8 9.1 6.6e-09 35.5 3.1 3.2 2 1 0 2 2 2 1 PX domain Glyco_hydro_25 PF01183.15 CCC67696.1 - 0.0084 15.9 1.1 0.022 14.5 0.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 25 MAS20 PF02064.10 CCC67697.1 - 1.1e-17 64.0 0.1 1.1e-17 64.0 0.1 2.4 2 1 0 2 2 2 1 MAS20 protein import receptor GOLD_2 PF13897.1 CCC67697.1 - 0.54 10.4 0.0 0.54 10.4 0.0 2.2 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DUF4149 PF13664.1 CCC67698.1 - 5.4e-20 71.3 2.4 8.7e-20 70.6 0.6 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) Oleosin PF01277.12 CCC67698.1 - 0.028 13.9 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Oleosin L51_S25_CI-B8 PF05047.11 CCC67699.1 - 1.3e-12 47.2 0.3 2.2e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain KID PF02524.9 CCC67699.1 - 0.79 10.0 3.9 20 5.9 0.6 2.9 2 0 0 2 2 2 0 KID repeat BCAS2 PF05700.6 CCC67700.1 - 4.9e-08 32.7 12.8 1.3e-05 24.7 8.9 2.5 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) R3H-assoc PF13902.1 CCC67700.1 - 1.1 9.2 7.7 0.48 10.3 1.9 2.4 1 1 1 2 2 2 0 R3H-associated N-terminal domain Ground-like PF04155.13 CCC67700.1 - 2.6 8.4 4.9 0.87 9.9 1.0 1.9 2 0 0 2 2 2 0 Ground-like domain CemA PF03040.9 CCC67700.1 - 3.1 7.3 5.7 11 5.5 1.5 2.1 2 0 0 2 2 2 0 CemA family DUF4028 PF13220.1 CCC67700.1 - 4.4 7.0 7.8 1.4 8.6 0.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4028) Ribosomal_L5_C PF00673.16 CCC67701.1 - 1.5e-23 82.3 0.0 2.3e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CCC67701.1 - 5.2e-21 74.1 0.3 1.4e-20 72.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L5 Proteasome PF00227.21 CCC67702.1 - 3.2e-49 166.7 0.1 3.9e-49 166.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Fork_head PF00250.13 CCC67703.1 - 5e-34 116.2 0.8 1.7e-33 114.5 0.2 2.2 1 1 1 2 2 2 1 Fork head domain FHA PF00498.21 CCC67703.1 - 1.2e-12 47.7 0.2 2.9e-12 46.5 0.2 1.7 1 0 0 1 1 1 1 FHA domain COG4 PF08318.7 CCC67704.1 - 1.8e-105 352.3 13.2 1.8e-105 352.3 9.2 1.7 2 0 0 2 2 2 1 COG4 transport protein Pil1 PF13805.1 CCC67705.1 - 5.8e-139 461.8 0.2 6.7e-139 461.6 0.2 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 zf-CCCH PF00642.19 CCC67706.1 - 5.1e-16 57.9 27.6 1.4e-05 24.5 0.4 5.6 4 2 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RPN7 PF10602.4 CCC67707.1 - 3.6e-48 163.2 3.2 3.6e-48 163.2 2.2 1.6 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 CCC67707.1 - 1e-15 57.8 0.1 3.1e-15 56.3 0.0 1.9 2 0 0 2 2 2 1 PCI domain Interferon PF00143.14 CCC67707.1 - 0.012 15.5 0.1 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Interferon alpha/beta domain DUF1910 PF08928.5 CCC67707.1 - 0.16 12.0 2.2 0.29 11.1 0.3 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1910) Merozoite_SPAM PF07133.6 CCC67707.1 - 3.5 7.5 9.0 0.15 11.9 1.6 2.0 1 1 1 2 2 2 0 Merozoite surface protein (SPAM) MFS_1 PF07690.11 CCC67708.1 - 4.6e-10 38.7 40.6 2.3e-08 33.1 26.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCC67708.1 - 3.5e-05 22.5 10.0 3.5e-05 22.5 7.0 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter OppC_N PF12911.2 CCC67708.1 - 8.6 5.8 8.3 13 5.2 0.5 3.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF1746 PF08508.5 CCC67709.1 - 0.0017 18.2 3.8 0.48 10.3 0.1 3.1 3 0 0 3 3 3 2 Fungal domain of unknown function (DUF1746) DUF4401 PF14351.1 CCC67709.1 - 0.025 13.5 0.2 0.037 13.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4401) EpsG PF14897.1 CCC67709.1 - 2.1 7.1 8.6 0.16 10.8 1.8 1.8 2 0 0 2 2 2 0 EpsG family RNA_pol_A_bac PF01000.21 CCC67710.1 - 2.4e-28 98.4 0.0 4.6e-28 97.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CCC67710.1 - 2.9e-16 58.3 0.0 4.2e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Pkinase PF00069.20 CCC67711.1 - 1.3e-53 181.8 0.0 1.2e-52 178.6 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67711.1 - 9e-28 97.0 0.7 8.2e-20 70.9 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase_C PF00433.19 CCC67711.1 - 3.5e-06 27.4 1.4 8.1e-06 26.2 1.0 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCC67711.1 - 0.00029 19.8 0.2 0.0035 16.3 0.1 2.2 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCC67711.1 - 0.016 14.2 0.0 0.03 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC67711.1 - 0.039 13.6 0.0 0.2 11.3 0.0 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family RRM_1 PF00076.17 CCC67712.1 - 2e-66 219.5 12.9 5.3e-17 61.2 0.1 6.4 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC67712.1 - 5.2e-62 205.7 2.8 1.8e-15 56.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC67712.1 - 6.7e-38 128.3 0.1 4.2e-09 36.1 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCC67712.1 - 0.00043 19.9 0.0 2.6 7.8 0.0 4.0 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Chorismate_synt PF01264.16 CCC67712.1 - 0.034 12.6 0.0 0.077 11.4 0.0 1.6 1 0 0 1 1 1 0 Chorismate synthase NAD_binding_9 PF13454.1 CCC67712.1 - 0.065 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding tRNA-synt_1 PF00133.17 CCC67713.1 - 1.4e-230 766.3 0.0 8.6e-230 763.8 0.0 2.1 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCC67713.1 - 6.8e-33 113.5 2.8 2.3e-32 111.8 1.9 2.0 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCC67713.1 - 2.1e-18 66.1 0.1 1.6e-09 36.9 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CCC67713.1 - 6.5e-08 32.0 12.7 3.7e-07 29.6 0.0 3.9 3 1 1 4 4 4 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 CCC67713.1 - 0.00057 19.9 8.9 0.00057 19.9 6.2 3.2 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 CCC67713.1 - 0.0013 17.8 0.6 0.63 9.1 0.0 3.4 3 1 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain Lzipper-MIP1 PF14389.1 CCC67713.1 - 0.025 14.6 3.1 0.068 13.2 2.1 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 CDP-OH_P_transf PF01066.16 CCC67714.1 - 2e-18 66.5 3.9 4.4e-18 65.4 2.7 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase TRAM_LAG1_CLN8 PF03798.11 CCC67715.1 - 2.1e-28 99.2 18.9 2.1e-28 99.2 13.1 1.5 2 0 0 2 2 2 1 TLC domain Fmp27_WPPW PF10359.4 CCC67717.1 - 4.4e-127 424.3 5.3 6.6e-127 423.8 3.6 1.3 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 CCC67717.1 - 1e-98 331.2 1.3 1e-98 331.2 0.9 1.9 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 CCC67717.1 - 2.4e-44 151.0 0.1 1.6e-43 148.3 0.0 2.4 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CCC67717.1 - 3.5e-38 130.8 1.7 3.5e-38 130.8 1.2 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CCC67717.1 - 2.2e-22 79.4 0.4 1.7e-20 73.3 0.0 3.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain NPV_P10 PF05531.7 CCC67717.1 - 2.5 8.4 10.8 0.31 11.3 0.5 4.1 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein IF-2B PF01008.12 CCC67718.1 - 4.5e-83 278.5 0.0 5.5e-83 278.2 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Cyclin_N PF00134.18 CCC67719.1 - 3.8e-43 146.0 0.3 1.4e-42 144.2 0.2 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCC67719.1 - 1.6e-16 60.2 0.0 4.4e-16 58.8 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain SBP_bac_6 PF13343.1 CCC67719.1 - 0.049 12.9 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Cyclin_N PF00134.18 CCC67720.1 - 2.3e-40 137.0 0.3 9.9e-40 135.0 0.2 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCC67720.1 - 4.3e-31 107.2 0.0 1.1e-30 105.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Wzz PF02706.10 CCC67720.1 - 0.2 11.4 3.7 0.53 10.1 2.6 1.6 1 0 0 1 1 1 0 Chain length determinant protein Peptidase_M16 PF00675.15 CCC67721.1 - 1.3e-32 112.5 0.1 9.5e-32 109.8 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCC67721.1 - 8.3e-15 54.9 1.4 4.6e-05 23.1 0.0 4.9 4 1 0 4 4 4 3 Peptidase M16 inactive domain Ctr PF04145.10 CCC67722.1 - 3.6e-27 95.1 4.2 3.6e-27 95.1 2.9 2.7 3 0 0 3 3 3 1 Ctr copper transporter family DUF4229 PF14012.1 CCC67722.1 - 2.5 8.0 11.6 0.077 12.9 3.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) SH2_2 PF14633.1 CCC67723.1 - 1.5e-104 347.8 2.5 1.5e-104 347.8 1.8 2.4 2 0 0 2 2 2 1 SH2 domain YqgF PF14639.1 CCC67723.1 - 4.5e-63 211.3 0.0 1.6e-62 209.5 0.0 2.0 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 CCC67723.1 - 1.7e-50 169.9 4.7 1.7e-50 169.9 3.3 5.2 3 1 1 5 5 5 1 Death-like domain of SPT6 HHH_7 PF14635.1 CCC67723.1 - 3.8e-45 152.2 0.1 1.2e-44 150.6 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HTH_44 PF14641.1 CCC67723.1 - 2.2e-34 118.0 3.9 2.2e-34 118.0 2.7 3.1 3 0 0 3 3 3 1 Helix-turn-helix DNA-binding domain of SPT6 SPT6_acidic PF14632.1 CCC67723.1 - 1.5e-22 79.5 26.9 1.5e-22 79.5 18.6 5.6 3 1 2 5 5 5 1 Acidic N-terminal SPT6 SH2 PF00017.19 CCC67723.1 - 2.4e-12 46.4 0.1 8.6e-12 44.6 0.0 2.1 1 0 0 1 1 1 1 SH2 domain LETM1 PF07766.8 CCC67724.1 - 4.6e-93 311.1 3.1 4.6e-93 311.1 2.1 1.7 2 0 0 2 2 2 1 LETM1-like protein Aldo_ket_red PF00248.16 CCC67725.1 - 1.1e-43 149.1 0.0 1.2e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SF3a60_bindingd PF12108.3 CCC67725.1 - 0.032 13.7 0.5 0.081 12.4 0.4 1.8 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain CENP-X PF09415.5 CCC67725.1 - 0.032 14.0 0.1 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Mito_carr PF00153.22 CCC67726.1 - 6.2e-54 179.6 1.9 2e-19 69.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acetyltransf_1 PF00583.19 CCC67727.1 - 8.2e-11 41.7 0.0 1.2e-10 41.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCC67727.1 - 2.3e-05 24.4 0.0 4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCC67727.1 - 7.2e-05 22.4 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 CCC67727.1 - 0.0003 20.8 0.0 0.00043 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCC67727.1 - 0.036 13.9 0.0 0.048 13.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosom_S12_S23 PF00164.20 CCC67728.1 - 7.9e-41 138.3 0.5 9.3e-41 138.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Med26 PF08711.6 CCC67729.1 - 5.3e-15 54.6 0.5 1.3e-14 53.4 0.0 1.9 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Phasin PF05597.6 CCC67729.1 - 0.021 14.5 1.5 0.053 13.2 1.0 1.8 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Tom5 PF10642.4 CCC67730.1 - 7.2e-22 76.7 0.9 7.7e-22 76.6 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase DUF3639 PF12341.3 CCC67732.1 - 3.3e-11 42.9 0.0 7.3e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3639) WD40 PF00400.27 CCC67732.1 - 0.0056 16.5 0.2 0.35 10.8 0.1 3.2 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF3598 PF12204.3 CCC67732.1 - 0.028 13.6 0.1 0.091 11.9 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) WD40 PF00400.27 CCC67733.1 - 1.8e-20 72.0 2.4 3.8e-07 29.7 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Ammonium_transp PF00909.16 CCC67734.1 - 7.1e-119 396.8 23.0 8.2e-119 396.6 16.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family ABC2_membrane_2 PF12679.2 CCC67734.1 - 9.7 4.9 12.9 0.21 10.4 3.2 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein YTH PF04146.10 CCC67735.1 - 8.8e-41 138.7 1.1 8.8e-41 138.7 0.8 1.9 2 0 0 2 2 2 1 YT521-B-like domain EVE PF01878.13 CCC67735.1 - 0.039 13.9 0.0 0.082 12.9 0.0 1.6 1 0 0 1 1 1 0 EVE domain CBFD_NFYB_HMF PF00808.18 CCC67736.1 - 0.00083 19.3 0.2 0.00099 19.1 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCC67736.1 - 0.016 15.3 0.5 0.023 14.8 0.2 1.4 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 DUF1931 PF09123.6 CCC67736.1 - 0.039 13.9 0.1 0.046 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1931) AAA_32 PF13654.1 CCC67736.1 - 0.041 12.5 0.4 0.047 12.3 0.3 1.0 1 0 0 1 1 1 0 AAA domain Frataxin_Cyay PF01491.11 CCC67736.1 - 0.071 12.9 0.1 0.083 12.6 0.1 1.3 1 1 0 1 1 1 0 Frataxin-like domain CART PF06373.6 CCC67736.1 - 0.15 12.0 0.2 0.22 11.5 0.2 1.3 1 0 0 1 1 1 0 Cocaine and amphetamine regulated transcript protein (CART) Pyr_redox_3 PF13738.1 CCC67737.1 - 3e-05 24.1 0.0 0.0094 16.0 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCC67737.1 - 0.00049 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CCC67737.1 - 0.0063 16.2 0.0 0.02 14.6 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCC67737.1 - 0.01 15.6 0.0 0.049 13.5 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CCC67737.1 - 0.024 14.7 0.0 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 CCC67737.1 - 0.044 12.6 0.0 0.077 11.8 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase F1F0-ATPsyn_F PF10791.4 CCC67738.1 - 3.2e-40 136.2 0.3 3.6e-40 136.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 CCC67738.1 - 0.0002 21.3 0.0 0.00031 20.7 0.0 1.3 1 1 0 1 1 1 1 Mitochondrial F1F0-ATP synthase, subunit f LSM PF01423.17 CCC67739.1 - 6.5e-15 54.4 0.0 7.8e-15 54.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCC67739.1 - 0.00041 20.2 0.0 0.00074 19.3 0.0 1.5 1 1 0 1 1 1 1 Ataxin 2 SM domain Complex1_LYR PF05347.10 CCC67740.1 - 1.4e-14 53.5 0.1 1.7e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 CCC67740.1 - 3e-11 43.3 0.1 3.6e-11 43.1 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like TPP_enzyme_N PF02776.13 CCC67741.1 - 1.4e-24 86.5 0.0 2.1e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCC67741.1 - 3.1e-17 62.6 0.0 5.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCC67741.1 - 2.2e-15 56.5 0.0 4.7e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain RRM_1 PF00076.17 CCC67742.1 - 2.8e-11 42.8 0.0 6.1e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC67742.1 - 2.8e-09 36.7 0.0 5e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC67742.1 - 2.1e-07 30.6 0.0 3.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CCC67742.1 - 0.0013 19.0 1.2 0.0013 19.0 0.8 3.0 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Mif2_N PF15624.1 CCC67742.1 - 4.9 7.7 7.3 2.7 8.5 1.4 2.2 2 0 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Mito_carr PF00153.22 CCC67744.1 - 4.6e-61 202.5 4.9 2e-20 72.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1092 PF06485.6 CCC67744.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) Ribosomal_60s PF00428.14 CCC67745.1 - 2.3e-23 82.4 7.9 2.7e-23 82.1 5.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Grp1_Fun34_YaaH PF01184.14 CCC67746.1 - 3.3e-67 225.8 18.3 4.2e-67 225.5 12.7 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3483 PF11982.3 CCC67746.1 - 0.67 9.2 2.4 0.88 8.8 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3483) GTP_EFTU PF00009.22 CCC67747.1 - 3.5e-63 212.4 0.3 5e-63 211.9 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCC67747.1 - 2.4e-37 127.1 0.0 8.1e-37 125.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CCC67747.1 - 3.2e-21 74.9 0.0 7.7e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CCC67747.1 - 2.7e-14 52.7 0.0 1.1e-13 50.8 0.0 2.1 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CCC67747.1 - 5.7e-14 51.9 0.5 1.4e-12 47.5 0.0 3.4 4 0 0 4 4 4 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCC67747.1 - 2.2e-05 24.3 0.1 5.1e-05 23.2 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SUKH-4 PF14435.1 CCC67747.1 - 0.12 12.0 0.0 0.45 10.2 0.0 1.9 1 0 0 1 1 1 0 SUKH-4 immunity protein ERCC4 PF02732.10 CCC67748.1 - 8.7e-22 77.4 0.1 1.7e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 ERCC4 domain RE_ScaI PF09569.5 CCC67748.1 - 0.021 14.3 0.0 4.2 6.8 0.0 2.4 2 0 0 2 2 2 0 ScaI restriction endonuclease HHH_3 PF12836.2 CCC67748.1 - 0.1 12.5 0.2 0.33 10.9 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif Sugar_tr PF00083.19 CCC67749.1 - 3.5e-100 335.7 32.4 1.2e-54 185.5 6.4 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 CCC67749.1 - 7.1e-36 123.6 51.3 9.6e-33 113.3 17.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCC67749.1 - 5.3e-05 21.8 8.9 5.3e-05 21.8 6.1 3.8 4 0 0 4 4 4 2 MFS/sugar transport protein Romo1 PF10247.4 CCC67749.1 - 0.075 13.2 2.4 0.14 12.3 0.3 2.4 2 0 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 Phage_holin_2 PF04550.7 CCC67749.1 - 0.25 11.4 10.2 0.046 13.8 1.1 3.7 4 0 0 4 4 4 0 Phage holin family 2 BAR PF03114.13 CCC67750.1 - 6.8e-62 208.9 6.5 8.6e-62 208.6 4.5 1.1 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 CCC67750.1 - 3.4e-14 51.9 0.0 6e-14 51.1 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCC67750.1 - 2.9e-12 45.9 0.2 4.7e-12 45.2 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCC67750.1 - 3.7e-08 32.7 0.0 6.7e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF755 PF05501.6 CCC67750.1 - 0.02 14.9 0.7 0.02 14.9 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF755) RhoGAP PF00620.22 CCC67751.1 - 5.9e-32 110.3 1.2 7.9e-31 106.7 0.8 2.2 1 1 0 1 1 1 1 RhoGAP domain Phlebovirus_NSM PF07246.6 CCC67751.1 - 0.0038 16.4 1.6 0.0068 15.5 1.1 1.4 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M CDC45 PF02724.9 CCC67751.1 - 1.7 6.6 12.9 0.026 12.5 3.5 1.9 2 0 0 2 2 2 0 CDC45-like protein Synaphin PF05835.7 CCC67751.1 - 3.3 7.8 18.5 3.8 7.6 0.1 3.0 3 0 0 3 3 3 0 Synaphin protein ThiF PF00899.16 CCC67752.1 - 4.8e-33 113.8 0.0 9.1e-33 112.9 0.0 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 CCC67752.1 - 1.5e-25 88.5 2.3 1.8e-25 88.2 0.5 2.0 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCC67752.1 - 5.6e-21 73.6 3.9 1e-20 72.8 2.7 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 CCC67752.1 - 3.2e-05 23.9 0.7 3.2e-05 23.9 0.5 2.7 3 0 0 3 3 3 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 CCC67752.1 - 0.023 14.9 0.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding TFIID-18kDa PF02269.11 CCC67753.1 - 6.4e-37 125.2 1.1 3.2e-36 123.0 0.1 2.4 3 0 0 3 3 3 1 Transcription initiation factor IID, 18kD subunit KH_1 PF00013.24 CCC67754.1 - 0.00032 20.3 0.4 0.00068 19.2 0.3 1.5 1 0 0 1 1 1 1 KH domain She9_MDM33 PF05546.6 CCC67755.1 - 1.2e-89 299.3 12.2 1.2e-89 299.3 8.5 2.4 2 0 0 2 2 2 1 She9 / Mdm33 family PsbH PF00737.15 CCC67755.1 - 0.023 14.2 0.3 0.053 13.1 0.2 1.6 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein PspA_IM30 PF04012.7 CCC67755.1 - 0.46 9.8 10.0 2 7.7 2.4 2.9 3 1 0 3 3 3 0 PspA/IM30 family Seryl_tRNA_N PF02403.17 CCC67755.1 - 2.1 8.4 19.5 5 7.1 5.1 3.4 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Med9 PF07544.8 CCC67755.1 - 2.9 7.7 9.0 2.1 8.1 0.8 3.3 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 AAA PF00004.24 CCC67756.1 - 2.3e-46 157.2 0.2 6.7e-46 155.7 0.0 1.9 3 0 0 3 3 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCC67756.1 - 1.4e-08 34.5 0.1 5.4e-08 32.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCC67756.1 - 3.2e-08 33.6 0.0 6.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCC67756.1 - 3.9e-07 30.2 0.1 1.6e-06 28.2 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCC67756.1 - 3e-06 27.4 2.8 0.00014 21.9 0.3 3.0 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 CCC67756.1 - 2.6e-05 24.0 0.1 0.00033 20.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 CCC67756.1 - 8.6e-05 21.5 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 CCC67756.1 - 0.00012 22.8 0.1 0.00052 20.8 0.0 2.0 2 0 0 2 2 1 1 AAA domain RuvB_N PF05496.7 CCC67756.1 - 0.00036 19.6 0.0 0.00083 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 CCC67756.1 - 0.00049 19.8 0.0 0.0015 18.2 0.0 1.9 1 0 0 1 1 1 1 NTPase Zeta_toxin PF06414.7 CCC67756.1 - 0.00081 18.5 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 CCC67756.1 - 0.0015 18.2 0.1 0.0037 16.9 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 CCC67756.1 - 0.0018 17.9 0.0 0.0085 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 CCC67756.1 - 0.0019 17.8 0.0 0.005 16.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CCC67756.1 - 0.002 18.2 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 CCC67756.1 - 0.0027 16.4 0.0 0.0047 15.6 0.0 1.5 1 1 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 CCC67756.1 - 0.003 17.4 0.0 0.0078 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CCC67756.1 - 0.0032 17.1 0.2 0.052 13.1 0.0 2.5 1 1 1 2 2 2 1 NACHT domain AAA_28 PF13521.1 CCC67756.1 - 0.0036 17.2 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCC67756.1 - 0.0042 16.6 0.0 0.0097 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 CCC67756.1 - 0.0047 16.4 0.0 0.15 11.5 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 CCC67756.1 - 0.0058 15.8 0.1 0.015 14.4 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CCC67756.1 - 0.0059 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 CCC67756.1 - 0.0059 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 CCC67756.1 - 0.006 16.0 1.9 0.12 11.7 0.1 2.6 2 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 CCC67756.1 - 0.011 15.4 0.7 0.11 12.2 0.0 2.5 2 1 1 3 3 3 0 Archaeal ATPase AAA_18 PF13238.1 CCC67756.1 - 0.012 15.9 0.0 0.045 14.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 CCC67756.1 - 0.015 14.7 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 CCC67756.1 - 0.023 15.0 3.1 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 CCC67756.1 - 0.058 13.0 0.0 0.15 11.6 0.0 1.6 1 1 0 1 1 1 0 Bacterial dnaA protein NB-ARC PF00931.17 CCC67756.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain IBN_N PF03810.14 CCC67757.1 - 6.4e-15 54.8 0.2 1.9e-14 53.3 0.1 1.9 1 0 0 1 1 1 1 Importin-beta N-terminal domain Cse1 PF08506.5 CCC67757.1 - 1.8e-07 30.0 6.0 2.6e-07 29.5 2.5 2.5 2 1 0 2 2 2 1 Cse1 Telomerase_RBD PF12009.3 CCC67757.1 - 0.0025 17.7 0.1 0.0075 16.1 0.1 1.8 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RPT PF13446.1 CCC67757.1 - 0.037 13.4 0.0 7.6 6.0 0.0 2.9 2 0 0 2 2 2 0 A repeated domain in UCH-protein Vac14_Fab1_bd PF12755.2 CCC67757.1 - 0.063 13.6 0.5 0.77 10.1 0.1 3.2 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Pribosyltran PF00156.22 CCC67758.1 - 1.1e-10 41.3 0.0 1.9e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain 3Beta_HSD PF01073.14 CCC67758.1 - 0.1 11.2 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Mito_fiss_Elm1 PF06258.6 CCC67758.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission ELM1 IU_nuc_hydro PF01156.14 CCC67759.1 - 9.8e-76 254.9 0.0 1.1e-75 254.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase p450 PF00067.17 CCC67760.1 - 6.4e-56 189.7 0.1 8e-56 189.4 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DIT1_PvcA PF05141.7 CCC67761.1 - 4.4e-97 324.7 0.0 7.3e-97 324.0 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein SHS2_Rpb7-N PF03876.12 CCC67762.1 - 6e-16 58.3 0.0 1.2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CCC67762.1 - 1e-15 57.5 0.1 1.5e-15 57.0 0.1 1.2 1 0 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 CCC67762.1 - 3.3e-06 27.3 0.0 6.6e-06 26.3 0.0 1.5 1 1 1 2 2 2 1 RNA polymerase III subunit Rpc25 Ribosomal_L23 PF00276.15 CCC67763.1 - 7.6e-22 77.0 0.0 1.4e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 ABC2_membrane PF01061.19 CCC67764.1 - 6.8e-86 286.7 55.1 9.2e-44 149.1 13.1 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 CCC67764.1 - 6.4e-43 144.6 0.8 1.1e-36 124.6 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 CCC67764.1 - 1.1e-38 132.6 0.1 2.8e-18 66.5 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 CCC67764.1 - 5.5e-23 80.8 0.0 1.4e-22 79.5 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CCC67764.1 - 4.3e-08 32.7 0.0 0.00011 21.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.2 CCC67764.1 - 4.4e-07 29.2 34.5 0.00032 19.8 7.0 2.9 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 CCC67764.1 - 4.5e-06 26.7 0.4 0.00022 21.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CCC67764.1 - 0.00014 21.1 0.0 0.0068 15.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 CCC67764.1 - 0.00016 21.5 0.0 0.14 12.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CCC67764.1 - 0.00016 21.3 0.2 0.32 10.7 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain cobW PF02492.14 CCC67764.1 - 0.00036 20.0 0.6 0.23 10.8 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CCC67764.1 - 0.00043 20.5 0.0 0.17 12.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCC67764.1 - 0.00075 18.9 2.1 0.005 16.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCC67764.1 - 0.0016 18.5 0.1 0.5 10.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCC67764.1 - 0.0018 17.9 0.4 1.7 8.2 0.1 2.6 2 0 0 2 2 2 2 NACHT domain SMC_N PF02463.14 CCC67764.1 - 0.002 17.4 0.1 0.17 11.0 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_28 PF13521.1 CCC67764.1 - 0.0021 18.0 0.6 0.12 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CCC67764.1 - 0.0031 17.1 0.4 0.73 9.4 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 CCC67764.1 - 0.0031 17.5 0.0 0.044 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCC67764.1 - 0.0031 18.3 0.0 1.4 9.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CCC67764.1 - 0.0035 17.6 0.0 0.12 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCC67764.1 - 0.033 13.8 0.0 4.9 6.7 0.0 2.6 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 CCC67764.1 - 0.035 14.3 0.3 4.3 7.5 0.0 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CCC67764.1 - 0.057 12.9 0.3 1.6 8.2 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 CCC67764.1 - 0.22 11.0 3.4 6.3 6.3 0.2 3.1 3 0 0 3 3 3 0 AAA domain TRAPPC9-Trs120 PF08626.6 CCC67765.1 - 0 1060.7 36.0 0 1059.8 25.0 1.4 1 1 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Formyl_trans_N PF00551.14 CCC67766.1 - 1e-50 171.7 0.0 1.2e-50 171.5 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.13 CCC67766.1 - 0.032 13.8 0.1 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase PINIT PF14324.1 CCC67767.1 - 2.4e-35 121.7 0.2 2.4e-35 121.7 0.2 1.6 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.15 CCC67767.1 - 7e-21 73.4 7.9 1.3e-20 72.6 5.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CCC67767.1 - 3.3e-05 23.3 2.4 0.00011 21.6 1.7 1.9 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CCC67767.1 - 0.017 14.8 0.7 0.04 13.6 0.1 2.0 1 1 1 2 2 2 0 RING-type zinc-finger SAP PF02037.22 CCC67767.1 - 0.037 13.5 0.1 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 SAP domain zf-Sec23_Sec24 PF04810.10 CCC67767.1 - 0.091 12.3 0.2 0.54 9.8 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-C3HC4_2 PF13923.1 CCC67767.1 - 0.91 9.6 4.6 1.9 8.5 3.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ICMT PF04140.9 CCC67768.1 - 2e-29 101.6 1.2 3.2e-29 100.9 0.8 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 CCC67768.1 - 1.9e-15 56.8 3.1 2.5e-14 53.2 1.0 2.3 2 0 0 2 2 2 1 Phospholipid methyltransferase NnrU PF07298.6 CCC67768.1 - 8e-05 22.0 0.7 9.3e-05 21.8 0.1 1.4 2 0 0 2 2 2 1 NnrU protein DUF1295 PF06966.7 CCC67768.1 - 0.00011 21.5 0.2 0.00016 21.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2569 PF10754.4 CCC67768.1 - 0.14 12.3 10.9 1 9.5 2.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF2975 PF11188.3 CCC67768.1 - 4.9 6.8 7.6 7.5 6.2 0.8 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF2975) DER1 PF04511.10 CCC67769.1 - 1.6e-38 132.1 12.8 2.1e-38 131.8 8.9 1.1 1 0 0 1 1 1 1 Der1-like family Nop25 PF09805.4 CCC67770.1 - 1.2e-36 125.8 17.8 1.2e-36 125.8 12.3 2.1 2 0 0 2 2 2 1 Nucleolar protein 12 (25kDa) U6-snRNA_bdg PF10596.4 CCC67770.1 - 0.37 10.1 4.2 0.094 12.0 0.2 2.0 2 1 0 2 2 2 0 U6-snRNA interacting domain of PrP8 EXS PF03124.9 CCC67771.1 - 4.4e-53 180.5 26.7 5.3e-53 180.2 18.5 1.0 1 0 0 1 1 1 1 EXS family DUF3077 PF11275.3 CCC67771.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3077) Peptidase_M28 PF04389.12 CCC67772.1 - 2.8e-24 85.8 0.1 5.4e-24 84.9 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 CCC67772.1 - 6.4e-05 22.5 0.0 9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 ATP-synt_D PF01813.12 CCC67773.1 - 2.1e-64 216.7 4.1 2.7e-64 216.3 2.8 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Laminin_II PF06009.7 CCC67773.1 - 0.2 11.4 4.3 0.91 9.2 0.0 2.5 2 1 0 2 2 2 0 Laminin Domain II RICH PF05062.7 CCC67773.1 - 0.65 10.1 6.4 0.36 11.0 1.7 2.3 2 1 0 2 2 2 0 RICH domain Viral_P18 PF04521.8 CCC67773.1 - 5.3 6.5 7.5 7 6.1 0.2 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TPR_14 PF13428.1 CCC67774.1 - 1.6e-05 25.1 0.0 0.013 16.0 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCC67774.1 - 0.0001 22.1 0.0 0.0041 17.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCC67774.1 - 0.00052 20.6 0.0 0.0032 18.0 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCC67774.1 - 0.00089 19.0 1.3 0.0022 17.7 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCC67774.1 - 0.0026 17.3 0.0 0.013 15.2 0.0 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCC67774.1 - 0.016 14.9 1.4 0.15 11.8 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCC67774.1 - 0.034 13.7 0.1 0.34 10.5 0.0 2.7 3 1 1 4 4 4 0 TPR repeat TPR_6 PF13174.1 CCC67774.1 - 0.12 12.9 0.0 11 6.7 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L11_N PF03946.9 CCC67775.1 - 2.3e-17 62.1 0.6 6.6e-17 60.7 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CCC67775.1 - 2.7e-11 43.4 1.1 5.4e-11 42.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain IMS PF00817.15 CCC67776.1 - 2.6e-43 147.3 0.0 1.1e-42 145.3 0.0 2.0 3 0 0 3 3 3 1 impB/mucB/samB family IMS_C PF11799.3 CCC67776.1 - 1.4e-07 31.5 0.0 3.4e-07 30.2 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 CCC67776.1 - 0.0036 17.2 0.0 0.009 16.0 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif zf-C2H2_jaz PF12171.3 CCC67776.1 - 0.095 12.8 0.9 0.23 11.6 0.6 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CCC67776.1 - 0.21 11.9 1.1 0.6 10.5 0.8 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger RRM_5 PF13893.1 CCC67777.1 - 7.6e-13 48.1 0.1 1.5e-12 47.1 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCC67777.1 - 2.4e-09 36.7 0.2 4.6e-09 35.7 0.1 1.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC67777.1 - 9.4e-09 35.1 0.1 1.7e-08 34.2 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.20 CCC67778.1 - 5.9e-40 137.0 0.0 1e-39 136.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67778.1 - 1e-12 47.7 0.0 1.8e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCC67778.1 - 0.0044 16.0 0.0 0.0075 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCC67778.1 - 0.0056 15.6 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like HLH PF00010.21 CCC67779.1 - 9.3e-12 44.4 3.4 2.3e-11 43.1 2.3 1.7 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Lge1 PF11488.3 CCC67779.1 - 4.2 7.6 9.0 1.9 8.7 0.1 3.2 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 LicD PF04991.8 CCC67780.1 - 1.1e-47 162.8 3.5 1.1e-47 162.8 2.4 2.9 2 0 0 2 2 2 1 LicD family CN_hydrolase PF00795.17 CCC67781.1 - 1.2e-16 60.5 0.0 1.7e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PRCC PF10253.4 CCC67782.1 - 1.8e-07 32.0 6.2 4.2e-07 30.8 4.3 1.6 1 1 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Peptidase_S21 PF00716.12 CCC67782.1 - 0.068 12.4 0.8 0.077 12.3 0.6 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) DivIVA PF05103.8 CCC67782.1 - 0.081 12.9 6.4 0.11 12.5 4.5 1.2 1 0 0 1 1 1 0 DivIVA protein AKNA PF12443.3 CCC67782.1 - 0.19 11.7 1.3 0.28 11.2 0.9 1.4 1 1 0 1 1 1 0 AT-hook-containing transcription factor Cpn60_TCP1 PF00118.19 CCC67784.1 - 3.8e-143 477.6 3.3 4.4e-143 477.4 2.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Actin PF00022.14 CCC67785.1 - 2.8e-91 305.8 0.0 7.2e-91 304.5 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCC67785.1 - 1.4e-05 23.8 0.0 0.016 13.8 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein NOZZLE PF08744.5 CCC67785.1 - 0.0063 15.9 0.7 0.01 15.2 0.5 1.3 1 0 0 1 1 1 1 Plant transcription factor NOZZLE FAT PF02259.18 CCC67786.1 - 1.4e-124 415.6 6.4 2.7e-124 414.7 4.5 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 CCC67786.1 - 3.1e-60 203.5 1.0 1.5e-59 201.3 0.2 2.2 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 CCC67786.1 - 1.2e-51 174.7 1.2 1.2e-51 174.7 0.8 5.7 7 2 0 7 7 7 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 CCC67786.1 - 5e-38 129.2 1.3 5e-38 129.2 0.9 2.7 2 0 0 2 2 2 1 Rapamycin binding domain HEAT_2 PF13646.1 CCC67786.1 - 1.6e-18 66.7 0.0 0.00032 20.9 0.0 8.4 6 1 2 8 8 8 6 HEAT repeats FATC PF02260.15 CCC67786.1 - 6.3e-17 60.7 0.1 1.5e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 CCC67786.1 - 9.2e-14 50.2 3.7 0.0053 16.7 0.0 9.8 10 0 0 10 10 10 1 HEAT repeat HEAT_EZ PF13513.1 CCC67786.1 - 6.5e-13 48.7 1.7 3.5e-05 24.1 0.0 8.5 8 1 0 8 8 8 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CCC67786.1 - 2.9e-05 24.3 4.1 0.95 9.8 0.0 6.2 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Arm PF00514.18 CCC67786.1 - 0.0081 15.9 2.3 39 4.2 0.1 5.8 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat DUF3437 PF11919.3 CCC67786.1 - 0.075 12.7 0.0 11 5.7 0.0 3.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Yae1_N PF09811.4 CCC67787.1 - 1.4e-12 46.9 0.0 2.4e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Romo1 PF10247.4 CCC67787.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 AAA PF00004.24 CCC67788.1 - 4.2e-17 62.5 0.0 1.1e-16 61.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 CCC67788.1 - 6.2e-15 55.2 0.0 3.2e-14 52.9 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 CCC67788.1 - 8.8e-15 54.4 0.0 1.9e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 CCC67788.1 - 1.5e-11 43.7 0.1 8.1e-08 31.3 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 CCC67788.1 - 1.3e-06 27.6 0.1 3.4e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCC67788.1 - 1.4e-06 28.4 0.0 2.6e-05 24.3 0.0 2.7 2 2 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CCC67788.1 - 1.5e-05 24.7 0.0 2.5e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCC67788.1 - 2e-05 24.4 0.0 6.8e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCC67788.1 - 3e-05 23.7 0.0 6.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CCC67788.1 - 7.1e-05 22.8 0.0 0.0018 18.2 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 CCC67788.1 - 0.00053 19.2 0.0 0.0088 15.2 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 CCC67788.1 - 0.00074 19.1 0.4 0.0022 17.6 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCC67788.1 - 0.0012 19.5 0.0 0.0053 17.5 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CCC67788.1 - 0.0026 18.0 0.2 0.053 13.8 0.0 2.4 2 1 0 2 2 2 1 AAA domain DUF2075 PF09848.4 CCC67788.1 - 0.0035 16.3 0.0 0.0073 15.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CCC67788.1 - 0.0041 16.7 0.0 0.012 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 CCC67788.1 - 0.0055 15.6 0.0 0.01 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_10 PF12846.2 CCC67788.1 - 0.007 15.8 0.0 0.023 14.1 0.0 2.1 1 1 0 1 1 1 1 AAA-like domain AAA_5 PF07728.9 CCC67788.1 - 0.0076 15.9 0.1 0.077 12.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CCC67788.1 - 0.012 15.9 0.0 0.021 15.1 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCC67788.1 - 0.013 14.8 0.1 0.068 12.5 0.0 2.2 3 1 0 3 3 3 0 AAA domain TIP49 PF06068.8 CCC67788.1 - 0.014 14.1 0.1 0.13 10.8 0.0 2.2 2 0 0 2 2 2 0 TIP49 C-terminus Arch_ATPase PF01637.13 CCC67788.1 - 0.018 14.7 0.3 0.49 10.0 0.2 2.8 1 1 0 1 1 1 0 Archaeal ATPase ResIII PF04851.10 CCC67788.1 - 0.02 14.7 0.0 0.073 12.8 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit FtsK_SpoIIIE PF01580.13 CCC67788.1 - 0.023 14.2 0.1 0.075 12.5 0.0 1.8 1 1 1 2 2 2 0 FtsK/SpoIIIE family SNF2_N PF00176.18 CCC67788.1 - 0.032 13.0 0.0 0.66 8.7 0.0 2.2 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_3 PF07726.6 CCC67788.1 - 0.032 13.8 0.0 0.37 10.3 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CCC67788.1 - 0.033 14.1 0.0 0.071 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCC67788.1 - 0.065 13.4 0.6 0.2 11.8 0.0 2.2 3 1 0 3 3 2 0 RNA helicase AAA_33 PF13671.1 CCC67788.1 - 0.068 13.0 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Arch_fla_DE PF04659.8 CCC67788.1 - 0.077 12.8 0.1 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Archaeal flagella protein DNA_pol3_gamma3 PF12169.3 CCC67788.1 - 0.12 12.1 0.0 0.53 10.0 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III PAC2 PF09754.4 CCC67790.1 - 7.6e-28 97.8 0.0 1.9e-27 96.5 0.0 1.6 1 1 0 1 1 1 1 PAC2 family PEMT PF04191.8 CCC67791.1 - 4.6e-33 113.5 3.1 4.6e-33 113.5 2.1 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase CENP-C_C PF11699.3 CCC67792.1 - 6.6e-27 93.3 7.3 1.4e-26 92.2 1.0 3.0 2 1 1 3 3 3 1 Mif2/CENP-C like Mif2_N PF15624.1 CCC67792.1 - 3.9e-13 50.1 3.8 3.9e-13 50.1 2.6 3.0 1 1 1 3 3 3 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 CCC67792.1 - 0.00024 20.5 0.0 0.00038 19.8 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Tombus_movement PF05318.7 CCC67792.1 - 0.0083 16.7 1.9 0.021 15.4 0.1 2.5 2 0 0 2 2 2 1 Tombusvirus movement protein Lipase_chap PF03280.9 CCC67792.1 - 0.018 14.5 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 Proteobacterial lipase chaperone protein Pkinase PF00069.20 CCC67793.1 - 4.1e-72 242.4 0.0 7.6e-72 241.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67793.1 - 1.3e-48 165.3 0.0 2.2e-48 164.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 CCC67793.1 - 7.4e-13 48.7 0.3 4.5e-12 46.1 0.0 2.6 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 CCC67793.1 - 4e-07 29.2 0.0 1.1e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCC67793.1 - 0.063 12.9 0.0 0.16 11.6 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L10 PF00466.15 CCC67794.1 - 3.3e-19 68.6 0.1 5e-19 68.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 DUF4335 PF14233.1 CCC67795.1 - 0.014 14.8 0.1 0.019 14.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4335) Ribosomal_S2 PF00318.15 CCC67796.1 - 1.3e-59 200.9 0.0 2.7e-59 199.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S2 SIS_2 PF13580.1 CCC67796.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 SIS domain Sec7 PF01369.15 CCC67796.1 - 0.048 13.3 0.8 0.085 12.5 0.5 1.3 1 0 0 1 1 1 0 Sec7 domain Mito_carr PF00153.22 CCC67797.1 - 1e-46 156.5 6.7 1.2e-18 66.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Syja_N PF02383.13 CCC67798.1 - 3.1e-87 292.3 1.5 4.7e-87 291.7 1.0 1.3 1 0 0 1 1 1 1 SacI homology domain Gly_transf_sug PF04488.10 CCC67799.1 - 1.3e-12 47.9 0.4 6.2e-12 45.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif Dak2 PF02734.12 CCC67799.1 - 0.018 14.7 0.1 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 DAK2 domain Baculo_PEP_C PF04513.7 CCC67799.1 - 0.049 13.4 3.6 0.097 12.4 2.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 CCC67799.1 - 0.13 11.8 5.1 0.23 11.0 3.5 1.4 1 0 0 1 1 1 0 IncA protein DUF4446 PF14584.1 CCC67799.1 - 0.43 10.3 2.8 0.89 9.3 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) DUF4404 PF14357.1 CCC67799.1 - 1.8 9.0 7.5 6.7 7.2 4.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Mog1 PF04603.7 CCC67800.1 - 1.4e-19 70.3 0.9 6.1e-19 68.3 0.6 1.8 1 1 0 1 1 1 1 Ran-interacting Mog1 protein Thymidylat_synt PF00303.14 CCC67800.1 - 0.072 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Thymidylate synthase MEDS PF14417.1 CCC67800.1 - 0.09 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain dUTPase PF00692.14 CCC67801.1 - 1.6e-41 140.7 0.0 1.8e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 dUTPase MIS13 PF08202.6 CCC67802.1 - 6.3e-70 235.6 14.7 6.3e-70 235.6 10.2 1.5 2 0 0 2 2 2 1 Mis12-Mtw1 protein family V_ATPase_I PF01496.14 CCC67802.1 - 0.043 11.6 4.0 0.067 11.0 2.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3533 PF12051.3 CCC67802.1 - 0.047 12.4 0.4 0.072 11.8 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) WD40 PF00400.27 CCC67803.1 - 1.3e-10 40.6 15.3 0.00023 20.9 0.1 6.8 6 2 1 7 7 7 3 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCC67803.1 - 0.00015 21.1 0.0 0.0058 16.1 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Asp PF00026.18 CCC67804.1 - 8.2e-74 248.6 3.7 1.2e-73 248.1 2.5 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCC67804.1 - 5.5e-08 32.9 0.5 1.2e-07 31.7 0.3 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCC67804.1 - 0.018 14.5 0.0 0.047 13.2 0.0 1.8 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal BAG PF02179.11 CCC67805.1 - 9.7e-17 60.8 2.5 1.7e-16 60.0 1.7 1.3 1 0 0 1 1 1 1 BAG domain Phage_GP20 PF06810.6 CCC67805.1 - 0.11 11.9 3.2 0.19 11.1 2.1 1.4 1 1 0 1 1 1 0 Phage minor structural protein GP20 HEAT PF02985.17 CCC67806.1 - 0.0055 16.6 0.1 0.44 10.7 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat Ribosomal_L2_C PF03947.13 CCC67807.1 - 1.9e-41 140.9 1.8 3e-41 140.2 1.3 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCC67807.1 - 2.4e-13 49.8 0.1 5.2e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Ribosomal_L29e PF01779.12 CCC67808.1 - 2.1e-24 85.0 8.8 3e-24 84.5 6.1 1.2 1 0 0 1 1 1 1 Ribosomal L29e protein family His_biosynth PF00977.16 CCC67809.1 - 3e-25 88.8 0.0 3.7e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Histidine biosynthesis protein BtpA PF03437.10 CCC67809.1 - 0.026 13.8 0.0 0.047 12.9 0.0 1.4 1 0 0 1 1 1 0 BtpA family Aldolase PF01081.14 CCC67809.1 - 0.039 13.1 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 KDPG and KHG aldolase Tim44 PF04280.10 CCC67810.1 - 1.9e-32 112.2 0.5 5.5e-32 110.7 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain MCPVI PF02993.9 CCC67810.1 - 0.13 12.3 2.8 0.16 12.1 0.2 2.2 2 1 1 3 3 3 0 Minor capsid protein VI bZIP_1 PF00170.16 CCC67811.1 - 1.5e-06 28.0 15.4 2.9e-06 27.1 10.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor Glutaredoxin2_C PF04399.8 CCC67811.1 - 0.005 16.4 4.1 0.012 15.1 2.8 1.6 1 0 0 1 1 1 1 Glutaredoxin 2, C terminal domain SPT6_acidic PF14632.1 CCC67811.1 - 0.1 12.7 11.3 0.12 12.5 3.7 2.6 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Lge1 PF11488.3 CCC67811.1 - 2.6 8.3 8.8 0.61 10.3 3.1 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein LGE1 bZIP_2 PF07716.10 CCC67811.1 - 4.3 7.2 20.1 0.093 12.5 9.1 1.9 2 0 0 2 2 2 0 Basic region leucine zipper DUF763 PF05559.6 CCC67811.1 - 7.4 5.4 7.6 3.1 6.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF763) V_ATPase_I PF01496.14 CCC67811.1 - 8.7 4.0 7.0 11 3.7 4.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Form_Nir_trans PF01226.12 CCC67812.1 - 3.7e-63 212.7 20.8 4.7e-63 212.4 14.4 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter BRAP2 PF07576.7 CCC67813.1 - 1.6e-28 98.4 0.5 4.4e-27 93.8 0.1 2.5 2 0 0 2 2 2 1 BRCA1-associated protein 2 zf-UBP PF02148.14 CCC67813.1 - 8.6e-22 77.0 8.4 2.4e-21 75.5 5.8 1.8 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 CCC67813.1 - 2.7e-09 36.7 14.3 2.7e-09 36.7 9.9 2.1 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CCC67813.1 - 0.0001 21.9 12.7 0.0001 21.9 8.8 2.4 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 CCC67813.1 - 0.00018 21.1 10.1 0.00018 21.1 7.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCC67813.1 - 0.00038 20.5 8.3 0.00038 20.5 5.8 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CCC67813.1 - 0.00057 19.5 8.3 0.00088 18.9 4.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CCC67813.1 - 0.00087 18.9 14.5 0.00087 18.9 10.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC67813.1 - 0.001 19.0 14.0 0.001 19.0 9.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCC67813.1 - 0.02 14.6 6.0 0.075 12.8 4.1 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Pribosyl_synth PF14572.1 CCC67814.1 - 2.6e-41 141.4 3.5 1.1e-35 123.0 1.7 2.2 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CCC67814.1 - 1.6e-37 127.7 0.5 1.9e-36 124.3 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CCC67814.1 - 3.8e-12 46.0 0.9 2.1e-11 43.6 0.7 2.0 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Chlorosome_CsmC PF11098.3 CCC67814.1 - 0.0076 15.9 1.1 0.016 14.9 0.7 1.5 1 0 0 1 1 1 1 Chlorosome envelope protein C UPRTase PF14681.1 CCC67814.1 - 0.016 14.4 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase UDPGP PF01704.13 CCC67815.1 - 1.2e-189 630.1 0.0 1.5e-189 629.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Zn_clus PF00172.13 CCC67816.1 - 3.6e-07 29.9 10.5 6e-07 29.2 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OTU PF02338.14 CCC67817.1 - 1.3e-21 77.4 0.0 1.3e-21 77.4 0.0 2.3 2 1 0 2 2 2 1 OTU-like cysteine protease YchF-GTPase_C PF06071.8 CCC67818.1 - 9.9e-29 98.9 0.0 2e-28 97.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 CCC67818.1 - 4.6e-16 58.8 0.1 1.2e-15 57.5 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCC67818.1 - 0.00029 20.1 0.0 0.00074 18.8 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 CCC67818.1 - 0.014 15.2 0.0 0.029 14.2 0.0 1.5 1 0 0 1 1 1 0 TGS domain DUF1910 PF08928.5 CCC67818.1 - 0.076 13.0 4.6 0.73 9.8 3.2 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1910) Ribosomal_S10 PF00338.17 CCC67819.1 - 4.8e-27 93.6 1.0 5.7e-27 93.4 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF4075 PF13294.1 CCC67819.1 - 0.034 14.1 1.0 0.073 13.1 0.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4075) DUF276 PF03434.8 CCC67819.1 - 0.078 11.9 0.2 0.24 10.3 0.0 1.7 2 0 0 2 2 2 0 DUF276 SSF PF00474.12 CCC67820.1 - 1.5e-16 60.0 30.0 2.7e-16 59.2 20.8 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family DUF2207 PF09972.4 CCC67820.1 - 0.0069 15.0 0.1 0.0069 15.0 0.1 3.7 2 1 1 3 3 3 1 Predicted membrane protein (DUF2207) NifU PF01106.12 CCC67821.1 - 2.4e-24 84.8 0.0 3.8e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.6 CCC67821.1 - 7.6e-21 73.5 0.0 1.8e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal YojJ PF10372.4 CCC67821.1 - 0.039 13.8 0.4 0.085 12.7 0.3 1.5 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus HOOK PF05622.7 CCC67821.1 - 0.046 11.5 0.1 0.065 11.0 0.1 1.1 1 0 0 1 1 1 0 HOOK protein Pterin_4a PF01329.14 CCC67822.1 - 1.1e-25 89.1 0.2 1.3e-25 88.9 0.1 1.1 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Adap_comp_sub PF00928.16 CCC67823.1 - 1.9e-62 210.7 1.3 3.3e-62 209.9 0.9 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Opi1 PF08618.5 CCC67824.1 - 5.4e-33 114.5 6.9 4.1e-25 88.5 0.1 2.9 1 1 3 4 4 4 2 Transcription factor Opi1 Tom22 PF04281.8 CCC67824.1 - 2.1 7.8 33.9 0.072 12.6 4.3 3.4 3 0 0 3 3 3 0 Mitochondrial import receptor subunit Tom22 Prothymosin PF03247.9 CCC67824.1 - 5.1 7.2 55.1 0.084 13.0 6.5 3.6 4 0 0 4 4 4 0 Prothymosin/parathymosin family CLU PF13236.1 CCC67825.1 - 2.5e-68 229.8 0.6 8e-68 228.1 0.0 2.3 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 CCC67825.1 - 1.3e-32 113.0 7.6 2.3e-24 86.2 0.0 3.5 4 0 0 4 4 4 2 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 CCC67825.1 - 2.3e-12 46.8 1.1 1.1e-11 44.6 0.3 2.7 2 0 0 2 2 2 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 CCC67825.1 - 3.3e-09 36.5 0.0 2.4e-05 24.2 0.0 3.3 1 1 2 4 4 4 2 Tetratricopeptide repeat DUF727 PF05303.7 CCC67825.1 - 3.2e-06 26.8 0.1 1.5e-05 24.7 0.1 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_10 PF13374.1 CCC67825.1 - 0.0043 16.9 0.1 0.034 14.0 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCC67825.1 - 0.016 14.7 0.0 4.3 7.0 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCC67825.1 - 0.078 12.6 0.0 0.66 9.6 0.0 2.4 3 0 0 3 3 3 0 TPR repeat CTP_transf_1 PF01148.15 CCC67826.1 - 7.5e-07 29.0 1.5 7.5e-07 29.0 1.1 4.2 4 2 0 5 5 5 3 Cytidylyltransferase family DUF2809 PF10990.3 CCC67826.1 - 0.42 11.0 4.9 0.19 12.1 0.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2809) BUD22 PF09073.5 CCC67827.1 - 1e-90 304.9 42.8 1e-90 304.9 29.7 1.9 2 0 0 2 2 2 1 BUD22 DUF2294 PF10057.4 CCC67827.1 - 0.47 10.1 7.0 0.032 13.8 0.9 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) p450 PF00067.17 CCC67828.1 - 8.7e-51 172.8 0.2 1.1e-50 172.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 KilA-N PF04383.8 CCC67829.1 - 0.0012 18.4 0.0 0.0012 18.4 0.0 3.8 4 1 0 4 4 4 2 KilA-N domain Fungal_trans PF04082.13 CCC67830.1 - 1.2e-19 70.2 12.5 1.2e-19 70.2 8.6 2.3 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC67830.1 - 6.8e-10 38.6 12.9 6.8e-10 38.6 9.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amino_oxidase PF01593.19 CCC67831.1 - 2.7e-62 211.3 0.0 1.8e-61 208.6 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 CCC67831.1 - 8.2e-12 45.6 0.0 5.5e-06 26.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCC67831.1 - 4.7e-11 42.5 0.2 1.2e-10 41.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CCC67831.1 - 8.4e-05 21.7 0.2 0.00019 20.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 CCC67831.1 - 0.0002 20.3 1.4 0.00028 19.8 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 CCC67831.1 - 0.00027 19.5 1.4 0.0059 15.1 0.5 2.2 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 CCC67831.1 - 0.00049 19.1 0.2 0.0054 15.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCC67831.1 - 0.00085 19.2 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCC67831.1 - 0.001 18.1 0.1 0.0019 17.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 CCC67831.1 - 0.0011 17.8 1.2 0.0016 17.3 0.5 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 CCC67831.1 - 0.0014 19.0 2.1 0.1 13.0 0.4 2.9 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 CCC67831.1 - 0.014 15.4 0.1 0.031 14.3 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lycopene_cycl PF05834.7 CCC67831.1 - 0.073 11.9 0.5 1.9 7.3 0.3 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 CCC67831.1 - 0.13 12.0 0.1 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 ThiF family FAD_oxidored PF12831.2 CCC67831.1 - 0.15 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase UQ_con PF00179.21 CCC67832.1 - 1.4e-49 167.1 0.0 1.6e-49 166.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCC67832.1 - 0.024 14.3 0.0 0.045 13.5 0.0 1.4 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 CCC67832.1 - 0.058 13.2 1.0 0.083 12.7 0.7 1.7 1 1 0 1 1 1 0 RWD domain Glyco_hydro_76 PF03663.9 CCC67833.1 - 6.3e-154 512.8 26.5 8.3e-154 512.4 18.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 TrmE_N PF10396.4 CCC67834.1 - 8.3e-36 122.4 0.0 1.9e-35 121.2 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 CCC67834.1 - 7.7e-25 87.1 0.6 1.8e-24 85.9 0.4 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 CCC67834.1 - 8e-16 58.2 0.0 2.4e-15 56.7 0.0 1.9 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE FeoB_N PF02421.13 CCC67834.1 - 2.5e-12 46.3 1.1 5.5e-12 45.2 0.7 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CCC67834.1 - 4.8e-08 32.6 0.4 5.6e-06 25.9 0.1 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCC67834.1 - 4.9e-07 29.7 3.0 0.00022 21.1 0.3 2.7 2 0 0 2 2 2 2 Dynamin family Arf PF00025.16 CCC67834.1 - 1.8e-06 27.2 2.2 2.8e-05 23.4 1.5 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CCC67834.1 - 4.7e-06 27.0 0.1 1.4e-05 25.5 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 CCC67834.1 - 1.6e-05 24.1 0.9 3.5e-05 23.0 0.6 1.5 1 0 0 1 1 1 1 AIG1 family Ras PF00071.17 CCC67834.1 - 0.00018 20.9 0.0 0.00036 19.9 0.0 1.5 1 0 0 1 1 1 1 Ras family DUF258 PF03193.11 CCC67834.1 - 0.0011 18.2 0.1 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ArgK PF03308.11 CCC67834.1 - 0.0031 16.3 0.3 1.9 7.2 0.1 2.8 1 1 1 2 2 2 2 ArgK protein PduV-EutP PF10662.4 CCC67834.1 - 0.0038 16.7 0.1 1.4 8.3 0.1 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 CCC67834.1 - 0.047 12.7 2.9 0.6 9.0 0.0 2.3 1 1 1 2 2 2 0 Septin ABC_tran PF00005.22 CCC67834.1 - 0.056 13.7 1.5 0.16 12.2 1.0 1.9 1 1 0 1 1 1 0 ABC transporter Maelstrom PF13017.1 CCC67834.1 - 0.64 9.4 2.9 0.55 9.6 0.8 1.7 2 0 0 2 2 2 0 piRNA pathway germ-plasm component Ribonuclease_3 PF00636.21 CCC67835.1 - 1.1e-08 35.4 0.0 2.4e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 CCC67835.1 - 4.7e-07 30.2 0.0 2.1e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 CCC67835.1 - 0.098 12.6 0.0 0.32 10.9 0.0 2.0 1 1 0 1 1 1 0 Ribonuclease-III-like MitMem_reg PF13012.1 CCC67836.1 - 0.0033 17.5 1.5 0.0041 17.1 0.3 1.7 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Ribosomal_S15 PF00312.17 CCC67836.1 - 0.017 14.8 0.2 0.046 13.4 0.1 1.7 1 0 0 1 1 1 0 Ribosomal protein S15 Desmo_N PF06771.6 CCC67836.1 - 0.12 12.3 1.7 0.88 9.5 0.4 2.4 2 0 0 2 2 2 0 Viral Desmoplakin N-terminus Pex2_Pex12 PF04757.9 CCC67837.1 - 2.2e-32 112.3 8.1 2.8e-32 111.9 5.6 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 CCC67837.1 - 1.1e-05 25.2 6.2 2.1e-05 24.4 4.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCC67837.1 - 0.00015 21.3 3.8 0.00026 20.6 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCC67837.1 - 0.018 14.8 5.8 0.035 13.9 4.0 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 CCC67837.1 - 0.022 14.6 7.1 0.038 13.8 5.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CCC67837.1 - 0.58 9.8 5.4 1.1 8.9 3.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 CCC67837.1 - 1.2 8.6 7.7 2.4 7.6 0.2 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif DUF89 PF01937.14 CCC67838.1 - 1.2e-110 369.6 4.0 1.4e-110 369.4 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 TAP42 PF04177.7 CCC67839.1 - 3e-94 315.7 21.5 3.3e-94 315.6 14.9 1.0 1 0 0 1 1 1 1 TAP42-like family Prismane PF03063.15 CCC67839.1 - 0.058 11.7 0.3 0.096 11.0 0.2 1.3 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family DUF3888 PF13027.1 CCC67840.1 - 0.48 10.3 6.9 0.4 10.5 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3888) Striatin PF08232.7 CCC67841.1 - 5.1e-26 91.5 5.6 2e-23 83.1 1.3 2.5 1 1 1 2 2 2 2 Striatin family bPH_3 PF14470.1 CCC67841.1 - 0.0038 17.4 3.0 0.017 15.3 0.7 2.8 1 1 1 2 2 2 1 Bacterial PH domain Herpes_BLRF2 PF05812.7 CCC67841.1 - 0.016 15.0 0.9 0.032 14.0 0.6 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Mto2_bdg PF12808.2 CCC67841.1 - 0.3 11.2 2.5 0.57 10.3 1.7 1.4 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region CUE PF02845.11 CCC67842.1 - 6.5e-05 22.3 0.1 0.00013 21.3 0.1 1.5 1 0 0 1 1 1 1 CUE domain Frag1 PF10277.4 CCC67843.1 - 4.1e-76 255.2 18.6 4.8e-76 254.9 12.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF872 PF05915.7 CCC67843.1 - 0.056 13.3 3.2 2.3 8.0 0.0 2.6 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF3812 PF12757.2 CCC67844.1 - 1.7e-27 95.8 0.2 1.7e-27 95.8 0.1 5.4 4 2 2 6 6 6 1 Protein of unknown function (DUF3812) FCH PF00611.18 CCC67845.1 - 1.4e-15 57.1 0.8 5.5e-15 55.3 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4137 PF13593.1 CCC67846.1 - 2e-116 388.4 15.3 2.3e-116 388.2 10.6 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Peptidase_S24 PF00717.18 CCC67847.1 - 2.9e-07 30.0 0.1 6.8e-07 28.8 0.1 1.7 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 CCC67847.1 - 6.7e-05 22.4 0.0 0.002 17.6 0.0 2.2 1 1 0 2 2 2 1 Signal peptidase, peptidase S26 Rhodanese PF00581.15 CCC67848.1 - 1.2e-13 51.3 0.0 3.1e-13 50.0 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain zf-C2H2 PF00096.21 CCC67849.1 - 2.2e-14 52.8 9.1 1.1e-06 28.5 1.7 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC67849.1 - 1.4e-10 40.7 7.8 7.8e-05 22.7 1.4 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCC67849.1 - 2.1e-08 34.0 15.2 1.5e-07 31.3 1.6 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCC67849.1 - 2.2e-07 30.8 6.1 0.0012 18.9 0.4 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCC67849.1 - 2.3e-05 24.3 3.6 0.096 12.9 0.3 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-Di19 PF05605.7 CCC67849.1 - 8.6e-05 22.5 3.8 0.00015 21.7 2.1 1.8 2 0 0 2 2 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 CCC67849.1 - 0.00037 20.3 6.5 0.0065 16.3 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 CCC67849.1 - 0.00072 19.2 4.6 0.072 12.8 0.6 2.8 2 0 0 2 2 2 2 BED zinc finger GAGA PF09237.6 CCC67849.1 - 0.023 14.2 2.0 0.092 12.3 0.6 2.5 1 1 1 2 2 2 0 GAGA factor zf-C2H2_2 PF12756.2 CCC67849.1 - 0.051 13.6 3.7 5.6 7.1 0.2 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) DUF629 PF04780.7 CCC67849.1 - 0.073 11.5 4.0 0.92 7.9 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF629) zf-C2HC_2 PF13913.1 CCC67849.1 - 0.93 9.2 5.8 8.5 6.1 0.1 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 CCC67849.1 - 1.2 9.1 6.1 8.3 6.4 4.1 2.2 1 1 1 2 2 2 0 Zinc ribbon domain Sod_Cu PF00080.15 CCC67850.1 - 2.2e-08 34.3 0.0 4.6e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 CCC67850.1 - 5.5e-07 29.6 0.0 1.3e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Heavy-metal-associated domain PC4 PF02229.11 CCC67851.1 - 2.4e-20 71.4 0.1 4.9e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF4551 PF15087.1 CCC67851.1 - 8.5 4.6 10.1 10 4.3 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Bap31 PF05529.7 CCC67852.1 - 3.7e-32 111.3 4.8 4.2e-32 111.1 3.3 1.0 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like UPF0220 PF05255.6 CCC67852.1 - 0.0093 15.2 0.1 0.013 14.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DPM3 PF08285.6 CCC67852.1 - 0.18 11.6 3.7 0.21 11.4 0.1 2.4 2 1 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Aldo_ket_red PF00248.16 CCC67853.1 - 6.3e-53 179.4 0.0 7e-53 179.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SRF-TF PF00319.13 CCC67854.1 - 1.2e-23 82.0 0.1 1.7e-23 81.5 0.1 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 CCC67854.1 - 0.02 12.9 2.9 0.024 12.7 2.0 1.1 1 0 0 1 1 1 0 CDC45-like protein CENP-T PF15511.1 CCC67854.1 - 0.022 14.0 9.0 0.028 13.6 6.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 CCC67854.1 - 0.089 10.7 12.1 0.1 10.4 8.4 1.0 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CCC67854.1 - 0.33 9.4 13.3 0.4 9.1 9.2 1.0 1 0 0 1 1 1 0 Daxx Family Mpp10 PF04006.7 CCC67854.1 - 1.4 7.2 14.9 1.6 6.9 10.3 1.1 1 0 0 1 1 1 0 Mpp10 protein COPI_C PF06957.6 CCC67854.1 - 7.2 5.0 11.5 8.9 4.7 8.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus SRF-TF PF00319.13 CCC67855.1 - 2.8e-25 87.2 0.3 5.5e-25 86.3 0.2 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) PWWP PF00855.12 CCC67856.1 - 9.5e-21 73.8 0.2 3.4e-20 72.0 0.1 2.0 1 0 0 1 1 1 1 PWWP domain eIF-5a PF01287.15 CCC67857.1 - 8.8e-28 96.0 0.5 1.3e-27 95.5 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CCC67857.1 - 0.00074 19.1 0.4 0.0013 18.3 0.2 1.4 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 CCC67857.1 - 0.019 14.8 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain TcdB_toxin_midN PF12256.3 CCC67857.1 - 0.097 12.1 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region Cytochrom_C PF00034.16 CCC67858.1 - 9.7e-11 42.3 0.1 1.5e-10 41.7 0.1 1.3 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CCC67858.1 - 6.3e-08 32.6 3.1 6.5e-07 29.4 2.1 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CCC67858.1 - 0.1 12.0 1.5 0.22 10.9 0.1 2.1 2 1 1 3 3 3 0 Cytochrome c-550 domain NAD_kinase PF01513.16 CCC67859.1 - 2.2e-79 266.1 0.5 6.6e-79 264.6 0.0 1.8 2 0 0 2 2 2 1 ATP-NAD kinase DAGK_cat PF00781.19 CCC67859.1 - 0.1 12.0 0.0 0.4 10.1 0.0 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Isy1 PF06246.7 CCC67860.1 - 2.9e-46 157.9 16.9 3.3e-43 147.9 9.6 2.0 1 1 1 2 2 2 2 Isy1-like splicing family SHNi-TPR PF10516.4 CCC67860.1 - 0.05 12.8 0.1 0.12 11.6 0.1 1.6 1 0 0 1 1 1 0 SHNi-TPR Porin_4 PF13609.1 CCC67860.1 - 0.092 12.2 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Gram-negative porin Beta_elim_lyase PF01212.16 CCC67861.1 - 4.3e-76 255.8 0.0 5.3e-76 255.5 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase FAD_binding_2 PF00890.19 CCC67862.1 - 7.9e-71 239.0 0.0 9.3e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 CCC67862.1 - 5.2e-09 36.2 0.7 1.3e-05 25.2 0.1 3.4 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCC67862.1 - 2.3e-06 27.5 0.1 1.4e-05 25.0 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCC67862.1 - 6.8e-06 25.3 0.1 0.00092 18.3 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox_3 PF13738.1 CCC67862.1 - 0.00029 20.9 0.0 0.0039 17.2 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCC67862.1 - 0.00051 18.6 2.8 0.034 12.6 0.1 3.2 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.19 CCC67862.1 - 0.0036 16.2 0.0 0.012 14.5 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 CCC67862.1 - 0.0058 15.5 2.4 0.011 14.5 0.0 2.6 4 0 0 4 4 4 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 CCC67862.1 - 0.017 14.0 0.0 0.18 10.7 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 CCC67862.1 - 0.021 14.5 0.0 0.15 11.8 0.0 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 CCC67862.1 - 0.023 13.7 0.3 0.041 12.9 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain LRR_6 PF13516.1 CCC67863.1 - 0.57 10.4 24.4 1.3 9.2 0.0 7.7 8 0 0 8 8 8 0 Leucine Rich repeat AvrB_AvrC PF05394.6 CCC67864.1 - 0.017 14.1 3.1 0.019 13.9 0.6 2.0 2 0 0 2 2 2 0 Avirulence protein zf-HIT PF04438.11 CCC67866.1 - 3.8e-11 42.4 12.0 3.8e-11 42.4 8.3 2.0 2 0 0 2 2 2 1 HIT zinc finger zf-Mss51 PF13824.1 CCC67866.1 - 0.0012 18.6 5.3 0.0027 17.5 3.6 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.6 CCC67866.1 - 0.0015 18.0 0.0 0.0042 16.6 0.0 1.7 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain CDC14 PF08045.6 CCC67866.1 - 0.005 15.9 0.2 0.0064 15.6 0.1 1.2 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Shisa PF13908.1 CCC67866.1 - 0.041 14.0 1.2 0.06 13.5 0.8 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator zf-B_box PF00643.19 CCC67866.1 - 0.051 13.4 11.9 0.73 9.7 4.9 2.2 2 0 0 2 2 2 0 B-box zinc finger zf-MYND PF01753.13 CCC67866.1 - 0.52 10.2 12.2 0.14 12.0 5.8 1.9 2 0 0 2 2 2 0 MYND finger zf-C3HC4_2 PF13923.1 CCC67866.1 - 2.4 8.2 12.0 4.9 7.2 4.9 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GFO_IDH_MocA PF01408.17 CCC67867.1 - 1.4e-08 35.2 0.0 2.2e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCC67867.1 - 0.0026 17.5 0.0 0.0053 16.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain DUF4588 PF15251.1 CCC67868.1 - 2.1e-06 27.9 5.1 6.9e-06 26.2 3.5 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) Laminin_II PF06009.7 CCC67869.1 - 0.0011 18.7 1.7 0.0012 18.6 1.2 1.1 1 0 0 1 1 1 1 Laminin Domain II Prefoldin_2 PF01920.15 CCC67869.1 - 0.0032 17.1 5.0 0.0041 16.8 3.5 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF948 PF06103.6 CCC67869.1 - 0.0062 16.3 1.2 0.0078 16.0 0.9 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF948) FlxA PF14282.1 CCC67869.1 - 0.015 15.2 2.0 0.015 15.2 1.4 1.1 1 0 0 1 1 1 0 FlxA-like protein bZIP_1 PF00170.16 CCC67869.1 - 0.018 14.9 6.3 0.026 14.4 4.4 1.2 1 0 0 1 1 1 0 bZIP transcription factor DMPK_coil PF08826.5 CCC67869.1 - 0.026 14.4 5.9 0.041 13.7 4.0 1.5 1 1 0 1 1 1 0 DMPK coiled coil domain like Prefoldin PF02996.12 CCC67869.1 - 0.027 14.1 3.4 0.036 13.7 2.4 1.2 1 0 0 1 1 1 0 Prefoldin subunit Spectrin PF00435.16 CCC67869.1 - 0.028 14.7 3.6 0.03 14.6 2.5 1.1 1 0 0 1 1 1 0 Spectrin repeat FTO_CTD PF12934.2 CCC67869.1 - 0.041 13.4 1.6 0.052 13.1 1.1 1.1 1 0 0 1 1 1 0 FTO C-terminal domain Sec2p PF06428.6 CCC67869.1 - 0.042 13.7 6.9 0.051 13.4 4.8 1.2 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p V_ATPase_I PF01496.14 CCC67869.1 - 0.056 11.2 3.8 0.05 11.4 2.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GrpE PF01025.14 CCC67869.1 - 0.056 12.9 3.8 0.054 13.0 2.6 1.1 1 0 0 1 1 1 0 GrpE PilJ PF13675.1 CCC67869.1 - 0.058 13.7 0.3 0.059 13.6 0.2 1.0 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DivIC PF04977.10 CCC67869.1 - 0.067 12.6 1.4 0.08 12.4 0.9 1.2 1 0 0 1 1 1 0 Septum formation initiator P4Ha_N PF08336.6 CCC67869.1 - 0.071 12.9 3.2 0.074 12.8 2.2 1.1 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF3373 PF11853.3 CCC67869.1 - 0.081 11.4 2.4 0.084 11.3 1.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) bZIP_2 PF07716.10 CCC67869.1 - 0.095 12.5 7.6 0.14 11.9 5.3 1.2 1 0 0 1 1 1 0 Basic region leucine zipper HR1 PF02185.11 CCC67869.1 - 0.1 12.3 4.4 0.12 12.0 3.0 1.2 1 0 0 1 1 1 0 Hr1 repeat Viral_P18 PF04521.8 CCC67869.1 - 0.1 12.0 1.2 0.11 11.9 0.8 1.1 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF972 PF06156.8 CCC67869.1 - 0.11 12.8 3.9 0.14 12.5 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) AAA_32 PF13654.1 CCC67869.1 - 0.12 11.0 3.2 0.11 11.1 2.2 1.0 1 0 0 1 1 1 0 AAA domain DUF641 PF04859.7 CCC67869.1 - 0.13 12.0 2.4 0.14 11.9 1.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Ax_dynein_light PF10211.4 CCC67869.1 - 0.14 11.9 4.8 0.14 11.9 3.3 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain EMP24_GP25L PF01105.19 CCC67869.1 - 0.15 11.7 1.5 0.15 11.7 1.0 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD PhoU PF01895.14 CCC67869.1 - 0.19 12.2 1.8 0.21 12.0 1.3 1.1 1 0 0 1 1 1 0 PhoU domain DUF3251 PF11622.3 CCC67869.1 - 0.23 10.8 2.1 0.3 10.4 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) SlyX PF04102.7 CCC67869.1 - 0.23 11.8 3.8 0.27 11.6 2.6 1.3 1 1 0 1 1 1 0 SlyX FlaC_arch PF05377.6 CCC67869.1 - 0.23 11.3 5.3 0.26 11.1 0.9 1.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) Adeno_PIX PF03955.9 CCC67869.1 - 0.27 11.7 1.1 0.29 11.6 0.7 1.1 1 0 0 1 1 1 0 Adenovirus hexon-associated protein (IX) IncA PF04156.9 CCC67869.1 - 0.31 10.6 1.8 0.3 10.6 1.2 1.1 1 0 0 1 1 1 0 IncA protein DUF572 PF04502.8 CCC67869.1 - 0.31 10.1 6.0 0.29 10.3 4.2 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF572) APG6 PF04111.7 CCC67869.1 - 0.34 9.9 5.9 0.32 9.9 4.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 EAP30 PF04157.11 CCC67869.1 - 0.36 9.9 3.8 0.36 9.9 2.7 1.1 1 0 0 1 1 1 0 EAP30/Vps36 family Osmo_CC PF08946.5 CCC67869.1 - 0.76 9.8 4.5 1.2 9.2 3.1 1.3 1 0 0 1 1 1 0 Osmosensory transporter coiled coil YvrJ PF12841.2 CCC67869.1 - 1.2 8.5 4.1 1.5 8.1 0.4 2.5 2 1 1 3 3 3 0 YvrJ protein family Spc24 PF08286.6 CCC67869.1 - 1.3 8.7 6.7 1.5 8.5 4.6 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3901 PF13040.1 CCC67869.1 - 5.5 6.3 10.1 1.4 8.2 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3901) Syja_N PF02383.13 CCC67870.1 - 4.3e-59 199.8 3.4 4.4e-59 199.8 1.4 1.7 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.18 CCC67870.1 - 1.1e-19 71.3 0.0 1.8e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SNARE PF05739.14 CCC67871.1 - 9.2e-09 34.8 0.5 1.5e-08 34.2 0.4 1.4 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.4 CCC67871.1 - 0.0016 17.9 0.1 0.0019 17.6 0.1 1.1 1 0 0 1 1 1 1 Membrane fusion protein Use1 UBN2_2 PF14227.1 CCC67871.1 - 0.019 14.4 0.2 0.028 13.9 0.1 1.2 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type MAD PF05557.8 CCC67871.1 - 0.041 11.9 0.1 0.046 11.8 0.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Sipho_Gp157 PF05565.6 CCC67871.1 - 0.052 13.1 0.1 0.074 12.6 0.1 1.2 1 0 0 1 1 1 0 Siphovirus Gp157 Lebercilin PF15619.1 CCC67871.1 - 0.088 12.2 0.2 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Sec34 PF04136.10 CCC67871.1 - 0.21 11.2 1.0 0.82 9.3 0.1 1.9 1 1 1 2 2 2 0 Sec34-like family Synaptobrevin PF00957.16 CCC67871.1 - 0.73 9.4 6.6 1.8 8.2 4.6 1.7 1 1 0 1 1 1 0 Synaptobrevin Thioredoxin PF00085.15 CCC67872.1 - 2.5e-26 91.3 2.0 8.1e-20 70.4 0.0 4.3 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 CCC67872.1 - 7.1e-07 29.2 0.9 6e-06 26.1 0.2 2.7 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCC67872.1 - 0.047 13.8 0.2 2.7 8.1 0.0 3.1 2 0 0 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.1 CCC67872.1 - 0.078 13.1 1.2 3 8.0 0.0 3.4 3 1 0 3 3 3 0 Thioredoxin-like domain DUF2847 PF11009.3 CCC67872.1 - 0.27 10.8 1.7 0.51 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2847) Thioredoxin_4 PF13462.1 CCC67872.1 - 0.79 9.7 4.1 2.6 8.0 0.0 3.3 4 0 0 4 4 4 0 Thioredoxin Mito_carr PF00153.22 CCC67873.1 - 8e-71 233.8 0.1 2.1e-23 81.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Gti1_Pac2 PF09729.4 CCC67874.1 - 9e-48 162.3 0.0 2.5e-47 160.8 0.0 1.8 2 0 0 2 2 2 1 Gti1/Pac2 family PDZ PF00595.19 CCC67875.1 - 2.7e-05 24.2 0.6 6.8e-05 22.9 0.2 1.8 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_2 PF13180.1 CCC67875.1 - 0.00021 21.1 0.6 0.00039 20.2 0.0 1.7 2 0 0 2 2 2 1 PDZ domain GRASP55_65 PF04495.9 CCC67875.1 - 0.022 14.7 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain CAP_GLY PF01302.20 CCC67876.1 - 3.7e-17 61.7 0.1 5.9e-17 61.1 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 CCC67876.1 - 5.9e-13 48.1 18.1 0.011 15.2 0.9 6.5 3 2 2 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCC67876.1 - 2.8e-11 42.9 17.8 0.0025 17.5 1.0 5.8 3 2 3 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 CCC67876.1 - 8.1e-11 40.4 16.5 1.1 9.5 0.1 9.5 8 1 1 9 9 9 5 Leucine Rich Repeat LRR_6 PF13516.1 CCC67876.1 - 9.6e-10 37.5 14.4 1.3 9.2 0.1 8.8 8 1 1 9 9 9 4 Leucine Rich repeat LRR_7 PF13504.1 CCC67876.1 - 1.7e-06 27.2 5.8 11 6.7 0.1 8.6 8 1 1 9 9 9 1 Leucine rich repeat Helicase_C PF00271.26 CCC67877.1 - 2.9e-20 71.9 0.1 1.1e-19 70.0 0.1 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCC67877.1 - 1e-18 67.3 0.0 4.5e-18 65.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CCC67877.1 - 1.8e-17 63.7 0.0 1.8e-17 63.7 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCC67877.1 - 0.054 13.6 0.0 0.34 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain DXP_reductoisom PF02670.11 CCC67877.1 - 0.22 12.0 1.0 0.59 10.6 0.1 2.2 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF3210 PF11489.3 CCC67878.1 - 2.1e-17 63.1 36.3 2.1e-17 63.1 25.1 3.4 2 1 0 3 3 3 2 Protein of unknown function (DUF3210) DnaJ-X PF14308.1 CCC67879.1 - 2.3e-64 216.4 0.9 2.3e-64 216.4 0.6 2.2 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CCC67879.1 - 8.8e-25 86.2 0.9 3e-24 84.5 0.6 2.0 1 0 0 1 1 1 1 DnaJ domain Ndc1_Nup PF09531.5 CCC67879.1 - 0.74 8.1 3.9 1.1 7.6 2.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TEX15 PF15326.1 CCC67879.1 - 0.95 9.0 9.5 0.93 9.0 4.9 2.0 2 0 0 2 2 2 0 Testis expressed sequence 15 FAM60A PF15396.1 CCC67879.1 - 5.1 6.7 9.0 2.3 7.8 4.5 1.6 2 0 0 2 2 2 0 Protein Family FAM60A RRM_1 PF00076.17 CCC67880.1 - 6.1e-18 64.2 0.0 1.2e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC67880.1 - 9.8e-12 44.6 0.0 1.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC67880.1 - 7.2e-07 28.9 0.0 1.4e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EF-hand_4 PF12763.2 CCC67881.1 - 2.1e-25 88.4 0.0 1.1e-13 50.7 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CCC67881.1 - 1.9e-05 24.6 0.0 0.0002 21.4 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 CCC67881.1 - 0.00026 20.0 0.0 0.011 15.0 0.0 3.0 3 0 0 3 3 3 1 EF hand DUF1720 PF08226.6 CCC67881.1 - 0.001 19.0 12.9 0.001 19.0 8.9 8.2 2 2 4 6 6 6 3 Domain of unknown function (DUF1720) EF-hand_6 PF13405.1 CCC67881.1 - 0.0051 16.5 0.0 0.49 10.4 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain Peptidase_C48 PF02902.14 CCC67882.1 - 5.2e-35 121.0 2.5 5.2e-35 121.0 1.7 2.6 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain RINGv PF12906.2 CCC67883.1 - 3.3e-13 49.4 6.8 6.2e-13 48.5 4.7 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CCC67883.1 - 1.6 8.6 5.8 3.3 7.6 4.0 1.6 1 0 0 1 1 1 0 Ring finger domain MMgT PF10270.4 CCC67884.1 - 1.1e-22 80.4 0.1 1.3e-22 80.2 0.1 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter DUF2705 PF10920.3 CCC67884.1 - 0.044 12.9 2.1 0.053 12.7 1.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2705) Ycf4 PF02392.11 CCC67884.1 - 0.085 12.1 0.9 0.13 11.6 0.6 1.2 1 0 0 1 1 1 0 Ycf4 YrhK PF14145.1 CCC67884.1 - 7.2 6.3 6.3 11 5.7 0.2 2.3 1 1 1 2 2 2 0 YrhK-like protein Zip PF02535.17 CCC67886.1 - 5.9e-50 170.0 24.5 6.9e-48 163.2 12.8 3.1 2 1 0 2 2 2 2 ZIP Zinc transporter DUF3816 PF12822.2 CCC67886.1 - 7.8 6.3 13.7 0.092 12.6 2.3 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3816) cNMP_binding PF00027.24 CCC67887.1 - 8.6e-45 150.4 0.1 8.7e-23 79.9 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Cupin_2 PF07883.6 CCC67887.1 - 0.025 14.0 2.9 0.65 9.5 0.2 2.7 2 1 0 2 2 2 0 Cupin domain F_actin_cap_B PF01115.12 CCC67888.1 - 8.6e-104 345.9 0.7 1e-103 345.7 0.5 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Aminotran_5 PF00266.14 CCC67889.1 - 1.5e-19 69.9 0.0 1.9e-19 69.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CCC67889.1 - 4.9e-06 25.7 0.1 7.2e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 CCC67889.1 - 0.0019 16.6 0.0 0.0034 15.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 CCC67889.1 - 0.022 13.8 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family SHMT PF00464.14 CCC67889.1 - 0.1 10.9 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Pkinase PF00069.20 CCC67890.1 - 5.2e-54 183.1 3.6 8.6e-53 179.1 2.5 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67890.1 - 1.2e-17 63.8 0.3 3.2e-13 49.3 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 CCC67890.1 - 2.7e-05 24.0 0.0 0.0001 22.1 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCC67890.1 - 0.0054 16.3 0.3 0.014 15.0 0.1 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 CCC67890.1 - 0.1 11.6 0.3 0.21 10.6 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF496 PF04363.7 CCC67890.1 - 0.67 9.8 6.6 0.42 10.4 0.5 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF496) bZIP_1 PF00170.16 CCC67891.1 - 5.4e-13 48.6 10.0 1.6e-12 47.2 6.9 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCC67891.1 - 2.9e-06 26.9 8.0 2.9e-06 26.9 5.6 2.2 2 0 0 2 2 2 1 Basic region leucine zipper Curto_V2 PF07325.6 CCC67891.1 - 0.25 10.9 1.6 0.48 10.0 1.1 1.4 1 0 0 1 1 1 0 Curtovirus V2 protein Not3 PF04065.10 CCC67893.1 - 6.2e-89 297.2 29.4 6.2e-89 297.2 20.4 2.3 1 1 1 2 2 2 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 CCC67893.1 - 1.2e-26 93.1 2.1 2.3e-26 92.2 0.1 2.5 2 0 0 2 2 2 1 NOT2 / NOT3 / NOT5 family Metallophos PF00149.23 CCC67894.1 - 1.9e-30 105.7 9.4 3.1e-30 105.0 6.5 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Apq12 PF12716.2 CCC67895.1 - 0.00011 21.7 11.4 0.00011 21.7 7.9 1.9 2 0 0 2 2 2 1 Nuclear pore assembly and biogenesis DUF3810 PF12725.2 CCC67895.1 - 4.5 6.0 6.2 5.4 5.8 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) BAR_2 PF10455.4 CCC67896.1 - 2.8e-77 259.4 19.3 2.8e-77 259.4 13.4 1.7 1 1 1 2 2 2 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Inhibitor_I24 PF10465.4 CCC67896.1 - 0.078 12.7 0.0 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 PinA peptidase inhibitor Carbpep_Y_N PF05388.6 CCC67896.1 - 0.69 10.0 4.6 8 6.6 1.1 3.2 2 2 1 3 3 3 0 Carboxypeptidase Y pro-peptide Syntaxin_2 PF14523.1 CCC67896.1 - 1 9.4 21.3 0.1 12.6 0.8 3.3 2 1 1 3 3 3 0 Syntaxin-like protein DUF1664 PF07889.7 CCC67896.1 - 2.8 7.7 6.1 1.1 9.0 0.1 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) BCDHK_Adom3 PF10436.4 CCC67897.1 - 5.9e-29 100.7 1.3 9e-29 100.0 0.9 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCC67897.1 - 4.1e-17 61.8 0.0 6e-15 54.9 0.0 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 CCC67897.1 - 5.1e-05 22.9 0.1 9.1e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 CCC67897.1 - 6.8e-05 22.6 0.0 0.00016 21.4 0.0 1.6 1 1 0 1 1 1 1 Histidine kinase-like ATPase domain NAD_binding_1 PF00175.16 CCC67898.1 - 4.9e-29 101.0 0.1 1.1e-28 99.9 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCC67898.1 - 1e-27 96.1 0.0 1.5e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain FAD_binding_9 PF08021.6 CCC67898.1 - 0.0016 18.3 0.0 0.0026 17.6 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain NAD_binding_6 PF08030.7 CCC67898.1 - 0.0018 18.2 0.0 0.12 12.2 0.0 2.4 1 1 1 2 2 2 1 Ferric reductase NAD binding domain Nro1 PF12753.2 CCC67898.1 - 0.19 10.6 0.0 0.27 10.1 0.0 1.1 1 0 0 1 1 1 0 Nuclear pore complex subunit Nro1 ArfGap PF01412.13 CCC67899.1 - 3.4e-37 126.7 0.1 3.4e-37 126.7 0.1 2.5 2 1 2 4 4 4 1 Putative GTPase activating protein for Arf CBM_21 PF03370.8 CCC67900.1 - 9.3e-27 93.2 8.4 9.3e-27 93.2 5.8 2.5 2 1 0 2 2 2 1 Putative phosphatase regulatory subunit WD40 PF00400.27 CCC67901.1 - 1.1e-51 170.9 19.8 2.3e-10 39.9 0.7 7.8 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CCC67901.1 - 2e-13 49.3 6.1 0.002 16.3 0.1 5.3 1 1 4 6 6 6 5 Nucleoporin Nup120/160 F-box-like PF12937.2 CCC67901.1 - 2.6e-13 49.4 1.9 5.3e-13 48.4 1.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCC67901.1 - 1.2e-10 40.7 1.1 2.6e-10 39.6 0.7 1.6 1 0 0 1 1 1 1 F-box domain Nucleoporin_N PF08801.6 CCC67901.1 - 0.0003 19.6 3.3 0.038 12.7 0.0 3.6 2 1 1 3 3 3 2 Nup133 N terminal like Coatomer_WDAD PF04053.9 CCC67901.1 - 0.018 13.8 0.9 0.044 12.5 0.4 1.7 2 0 0 2 2 2 0 Coatomer WD associated region PRANC PF09372.5 CCC67901.1 - 0.023 14.6 2.7 0.064 13.2 1.6 2.0 1 1 0 1 1 1 0 PRANC domain PAN_4 PF14295.1 CCC67901.1 - 0.041 13.5 0.4 0.041 13.5 0.3 2.3 2 0 0 2 2 2 0 PAN domain EXS PF03124.9 CCC67902.1 - 6.6e-86 288.4 24.5 1.1e-85 287.7 17.0 1.4 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CCC67902.1 - 1e-32 114.0 18.2 1e-32 114.0 12.6 1.8 2 0 0 2 2 2 1 SPX domain E1-E2_ATPase PF00122.15 CCC67903.1 - 6e-29 100.7 0.0 1.1e-28 99.8 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 CCC67903.1 - 3.3e-14 53.8 0.0 1.2e-12 48.7 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCC67903.1 - 2e-09 37.8 0.2 6.8e-09 36.1 0.2 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCC67903.1 - 6e-08 32.5 0.0 3.3e-07 30.1 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCC67903.1 - 0.029 13.9 2.3 0.031 13.8 0.0 2.2 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase Steroid_dh PF02544.11 CCC67904.1 - 2.1e-06 27.5 8.6 2.1e-06 27.5 5.9 1.9 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Transp_cyt_pur PF02133.10 CCC67905.1 - 3.4e-94 315.8 43.9 4e-94 315.6 30.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin YojJ PF10372.4 CCC67905.1 - 0.24 11.3 0.5 6.1 6.7 0.1 2.4 2 0 0 2 2 2 0 Bacterial membrane-spanning protein N-terminus Cyclin PF08613.6 CCC67906.1 - 2.1e-45 154.7 1.7 2.1e-45 154.7 1.2 2.3 2 1 0 2 2 2 1 Cyclin Toxin_45 PF15524.1 CCC67906.1 - 0.055 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Putative toxin 45 Ribonuc_L-PSP PF01042.16 CCC67907.1 - 4e-43 146.0 0.4 4.7e-43 145.8 0.3 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peptidase_S13 PF02113.10 CCC67907.1 - 0.075 11.5 0.0 0.09 11.2 0.0 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family Ribosomal_L34e PF01199.13 CCC67908.1 - 5e-37 126.0 4.0 5e-37 126.0 2.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e EndIII_4Fe-2S PF10576.4 CCC67908.1 - 0.27 11.4 2.0 0.53 10.5 0.1 2.3 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III HAD_2 PF13419.1 CCC67909.1 - 5.3e-10 39.8 0.0 8.2e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCC67909.1 - 4.6e-08 32.6 0.0 7.8e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCC67909.1 - 3e-06 27.8 0.0 1.8e-05 25.2 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase SAP PF02037.22 CCC67910.1 - 8.7e-12 44.2 1.5 2e-11 43.1 1.0 1.6 1 0 0 1 1 1 1 SAP domain HeH PF12949.2 CCC67910.1 - 0.075 12.6 0.2 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 HeH/LEM domain ABC_tran_2 PF12848.2 CCC67910.1 - 0.12 12.2 1.9 0.25 11.2 1.3 1.5 1 0 0 1 1 1 0 ABC transporter MGC-24 PF05283.6 CCC67910.1 - 1.2 8.8 9.0 2.2 8.0 6.3 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) LIN37 PF15306.1 CCC67910.1 - 2.6 8.0 8.5 0.13 12.2 2.2 1.7 2 0 0 2 2 2 0 LIN37 Macoilin PF09726.4 CCC67910.1 - 3.8 5.6 8.5 3.1 5.9 4.7 1.4 1 1 0 1 1 1 0 Transmembrane protein Vhr1 PF04001.8 CCC67912.1 - 4.4e-46 154.7 1.5 1e-45 153.5 1.0 1.6 1 0 0 1 1 1 1 Transcription factor Vhr1 DUF2578 PF10843.3 CCC67913.1 - 1.8e-61 207.1 12.8 2.2e-61 206.9 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) DIX PF00778.12 CCC67913.1 - 0.018 14.7 0.9 0.018 14.7 0.7 2.3 2 0 0 2 2 2 0 DIX domain Ran_BP1 PF00638.13 CCC67914.1 - 2.4e-33 114.7 0.0 6e-33 113.4 0.0 1.7 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 CCC67914.1 - 0.011 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 WH1 domain MIP-T3 PF10243.4 CCC67914.1 - 5.8 5.2 34.5 8 4.7 23.9 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Methyltransf_31 PF13847.1 CCC67915.1 - 3.2e-26 91.7 0.2 4.8e-26 91.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC67915.1 - 2.5e-21 76.3 0.1 3.9e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCC67915.1 - 5.2e-09 36.1 0.0 7.9e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCC67915.1 - 1.2e-08 35.2 0.0 2.3e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC67915.1 - 1.3e-08 35.0 0.0 2.4e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCC67915.1 - 6.2e-08 33.0 0.0 1.2e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCC67915.1 - 3.6e-07 29.9 0.0 4.5e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCC67915.1 - 2.4e-06 27.0 0.0 3.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CCC67915.1 - 4.5e-06 26.4 0.0 7.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_20 PF12147.3 CCC67915.1 - 0.00081 18.3 0.1 0.0027 16.6 0.0 1.7 1 1 1 2 2 2 1 Putative methyltransferase Methyltransf_4 PF02390.12 CCC67915.1 - 0.0028 16.7 0.0 0.0037 16.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 CCC67915.1 - 0.0058 15.8 0.1 0.0072 15.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.7 CCC67915.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PrmA PF06325.8 CCC67915.1 - 0.036 13.1 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 CCC67915.1 - 0.042 13.4 0.0 0.095 12.2 0.0 1.6 2 1 0 2 2 2 0 Putative RNA methylase family UPF0020 DUF4367 PF14285.1 CCC67915.1 - 2.2 7.5 7.3 11 5.3 1.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4367) Fis1_TPR_C PF14853.1 CCC67916.1 - 4.4e-25 87.3 0.5 4.4e-25 87.3 0.3 1.6 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 CCC67916.1 - 2e-16 58.9 0.0 3.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_19 PF14559.1 CCC67916.1 - 0.00095 19.4 0.0 0.002 18.4 0.0 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat ETRAMP PF09716.5 CCC67916.1 - 0.012 15.4 0.1 0.012 15.4 0.1 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) TPR_2 PF07719.12 CCC67916.1 - 0.026 14.4 0.1 0.048 13.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Titin_Z PF09042.6 CCC67916.1 - 1.2 8.7 7.3 0.92 9.1 3.5 1.8 2 0 0 2 2 2 0 Titin Z Ribonuc_red_lgC PF02867.10 CCC67917.1 - 1.6e-214 713.4 0.0 2e-214 713.1 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CCC67917.1 - 5.5e-24 83.7 0.0 1.5e-23 82.4 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CCC67917.1 - 8.6e-17 61.3 0.6 4.1e-16 59.1 0.0 2.5 3 0 0 3 3 3 1 ATP cone domain LCCL PF03815.14 CCC67918.1 - 3.2e-06 27.0 0.0 5.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Fst_toxin PF13955.1 CCC67918.1 - 0.05 13.2 2.0 0.13 11.9 1.4 1.7 1 0 0 1 1 1 0 Toxin Fst, type I toxin-antitoxin system Ribosomal_S24e PF01282.14 CCC67919.1 - 7.1e-35 118.6 0.2 1.1e-34 118.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Y_phosphatase PF00102.22 CCC67920.1 - 4.5e-49 166.9 0.6 4.5e-49 166.9 0.4 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 CCC67920.1 - 0.00046 19.7 2.5 0.0091 15.5 0.0 3.1 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCC67920.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family MAM33 PF02330.11 CCC67921.1 - 2.4e-53 180.9 10.1 2.8e-53 180.6 7.0 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein DUF4163 PF13739.1 CCC67921.1 - 0.23 12.2 1.3 1.1 10.1 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) PCI PF01399.22 CCC67922.1 - 0.024 14.9 0.2 0.072 13.4 0.1 1.8 1 0 0 1 1 1 0 PCI domain HORMA PF02301.13 CCC67923.1 - 1.2e-47 162.1 0.4 3e-47 160.7 0.3 1.7 1 0 0 1 1 1 1 HORMA domain PHD_2 PF13831.1 CCC67923.1 - 0.057 12.7 7.3 0.1 11.9 4.3 2.0 1 1 1 2 2 2 0 PHD-finger C1_1 PF00130.17 CCC67923.1 - 3.8 7.2 11.7 0.07 12.8 2.8 2.1 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SPO22 PF08631.5 CCC67925.1 - 5.5e-59 199.5 10.7 5.5e-59 199.5 7.4 4.1 4 2 0 4 4 4 1 Meiosis protein SPO22/ZIP4 like TPR_12 PF13424.1 CCC67925.1 - 0.27 11.2 0.1 0.27 11.2 0.1 2.4 3 0 0 3 3 3 0 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.14 CCC67926.1 - 1.3e-52 177.4 0.0 2.5e-52 176.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCC67926.1 - 5.5e-37 126.2 0.0 1e-36 125.3 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCC67926.1 - 3.8e-05 23.6 0.1 8.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.1 CCC67926.1 - 0.0096 16.2 0.0 0.031 14.5 0.0 1.9 2 0 0 2 2 2 1 XdhC Rossmann domain AdoHcyase_NAD PF00670.16 CCC67926.1 - 0.044 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain AceK PF06315.6 CCC67926.1 - 0.088 11.0 0.1 0.14 10.4 0.1 1.2 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) Coatomer_E PF04733.9 CCC67927.1 - 2.9e-06 26.6 13.2 5.2e-06 25.8 9.2 1.4 1 1 0 1 1 1 1 Coatomer epsilon subunit Apc5 PF12862.2 CCC67927.1 - 0.032 14.0 0.9 0.055 13.3 0.1 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 CagE_TrbE_VirB PF03135.9 CCC67927.1 - 0.1 12.3 5.2 0.12 12.1 2.8 1.6 1 1 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system DUF1689 PF07954.6 CCC67928.1 - 6.3e-50 168.9 0.8 1.1e-49 168.1 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1689) tRNA-synt_2b PF00587.20 CCC67929.1 - 9.8e-47 158.7 1.1 2.5e-46 157.4 0.8 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCC67929.1 - 3.9e-22 78.0 1.3 9.3e-22 76.7 0.9 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 CCC67929.1 - 1.9e-14 53.2 0.0 4e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 CCC67929.1 - 4.9e-13 48.7 0.0 9.6e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain zf-CCHC PF00098.18 CCC67930.1 - 1.2e-10 40.8 39.9 6.9e-05 22.5 2.9 5.0 5 1 0 5 5 5 3 Zinc knuckle zf-CCHC_4 PF14392.1 CCC67930.1 - 0.021 14.4 29.7 0.029 14.0 0.2 5.3 4 1 1 5 5 5 0 Zinc knuckle zf-CCHC_2 PF13696.1 CCC67930.1 - 0.66 9.5 26.6 0.47 9.9 1.1 4.6 2 1 3 5 5 5 0 Zinc knuckle zf-CCHC_3 PF13917.1 CCC67930.1 - 7.6 6.3 23.2 5 6.9 0.0 3.9 2 1 1 3 3 3 0 Zinc knuckle Pmp3 PF01679.12 CCC67931.1 - 2e-21 75.4 4.0 2.7e-21 75.0 2.8 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator Aldo_ket_red PF00248.16 CCC67932.1 - 1.8e-46 158.2 0.0 2.3e-46 157.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_10 PF00331.15 CCC67932.1 - 0.0059 15.6 0.1 0.63 8.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 10 Peptidase_C8 PF03569.8 CCC67932.1 - 0.012 14.9 0.0 0.55 9.5 0.0 2.2 2 0 0 2 2 2 0 Peptidase family C8 HIT PF01230.18 CCC67933.1 - 2e-25 89.1 0.1 2.6e-25 88.7 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CCC67933.1 - 1.3e-10 41.5 0.2 2.1e-10 40.8 0.2 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CCC67933.1 - 0.0088 15.6 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF4566 PF15130.1 CCC67933.1 - 0.12 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4566) AAA PF00004.24 CCC67934.1 - 2.5e-99 328.6 0.0 2.4e-48 163.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CCC67934.1 - 3.1e-19 68.6 0.2 9.3e-19 67.1 0.2 1.9 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 CCC67934.1 - 1.4e-14 54.4 0.0 5.2e-07 29.7 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CCC67934.1 - 2.2e-13 49.8 0.0 1.7e-05 23.9 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCC67934.1 - 3.7e-12 46.6 0.0 0.00011 22.2 0.0 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CCC67934.1 - 6.3e-12 45.3 2.7 2.9e-06 27.0 0.0 4.0 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 CCC67934.1 - 2.7e-11 43.5 0.0 8.1e-06 25.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CCC67934.1 - 3.7e-11 43.9 0.0 0.0012 19.5 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 CCC67934.1 - 2.4e-10 40.6 4.1 0.0011 19.1 0.1 4.4 3 2 1 4 4 3 2 AAA domain TIP49 PF06068.8 CCC67934.1 - 3e-09 36.1 0.1 0.0011 17.7 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 CCC67934.1 - 6.4e-09 35.7 0.0 0.0038 17.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 CCC67934.1 - 1e-07 31.5 7.7 0.056 12.8 0.1 4.5 2 2 2 4 4 4 2 AAA domain IstB_IS21 PF01695.12 CCC67934.1 - 1e-07 31.5 0.0 0.0073 15.7 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 CCC67934.1 - 1.6e-07 31.4 0.0 0.0068 16.5 0.0 3.0 3 0 0 3 3 2 2 RNA helicase CDC48_2 PF02933.12 CCC67934.1 - 2.5e-07 30.2 0.0 6.9e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Mg_chelatase PF01078.16 CCC67934.1 - 4.5e-07 29.2 0.5 0.03 13.4 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CCC67934.1 - 5.9e-07 28.7 0.0 0.013 14.6 0.0 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_19 PF13245.1 CCC67934.1 - 9.7e-07 28.4 2.7 0.036 13.8 0.1 2.8 2 0 0 2 2 2 2 Part of AAA domain AAA_24 PF13479.1 CCC67934.1 - 2.3e-06 27.3 0.1 0.1 12.1 0.0 3.1 3 0 0 3 3 3 2 AAA domain KaiC PF06745.8 CCC67934.1 - 2.4e-06 26.8 3.0 0.24 10.5 0.0 3.8 2 2 2 4 4 4 2 KaiC ResIII PF04851.10 CCC67934.1 - 5.8e-06 26.2 0.1 0.0083 15.9 0.0 2.8 3 0 0 3 3 2 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 CCC67934.1 - 1.1e-05 25.6 0.0 0.14 12.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 CCC67934.1 - 1.3e-05 24.7 0.1 0.13 11.7 0.0 3.4 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_28 PF13521.1 CCC67934.1 - 1.5e-05 25.0 0.0 0.24 11.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 CCC67934.1 - 1.7e-05 24.6 0.2 1.8 8.2 0.0 4.2 2 2 1 3 3 3 1 Archaeal ATPase PhoH PF02562.11 CCC67934.1 - 2.5e-05 23.6 0.5 0.11 11.6 0.1 2.4 2 0 0 2 2 2 2 PhoH-like protein Parvo_NS1 PF01057.12 CCC67934.1 - 2.8e-05 23.1 0.1 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 DUF815 PF05673.8 CCC67934.1 - 3.2e-05 22.9 0.0 0.052 12.4 0.0 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_11 PF13086.1 CCC67934.1 - 3.6e-05 23.4 0.0 0.25 10.9 0.0 2.6 2 1 0 2 2 2 2 AAA domain Sigma54_activ_2 PF14532.1 CCC67934.1 - 4.1e-05 23.6 0.0 0.17 11.9 0.0 2.7 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 CCC67934.1 - 4.3e-05 23.8 0.0 0.053 13.8 0.0 3.6 2 1 0 2 2 2 1 ABC transporter Bac_DnaA PF00308.13 CCC67934.1 - 4.6e-05 23.1 0.0 0.1 12.2 0.0 3.1 3 0 0 3 3 3 1 Bacterial dnaA protein Vps4_C PF09336.5 CCC67934.1 - 5.9e-05 22.8 0.1 0.00074 19.3 0.0 2.6 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain NACHT PF05729.7 CCC67934.1 - 0.00012 21.7 0.2 1.6 8.3 0.0 3.8 4 0 0 4 4 4 1 NACHT domain AAA_3 PF07726.6 CCC67934.1 - 0.00013 21.6 0.0 0.66 9.5 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CCC67934.1 - 0.0005 19.1 0.0 0.67 8.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CCC67934.1 - 0.00076 19.1 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 CCC67934.1 - 0.0054 15.6 0.1 1.7 7.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain IPT PF01745.11 CCC67934.1 - 0.013 14.6 0.1 1.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Isopentenyl transferase KAP_NTPase PF07693.9 CCC67934.1 - 0.013 14.4 0.2 1.7 7.5 0.0 2.9 2 2 1 3 3 3 0 KAP family P-loop domain Zot PF05707.7 CCC67934.1 - 0.026 13.9 0.3 5.8 6.3 0.1 3.5 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) NTPase_1 PF03266.10 CCC67934.1 - 0.035 13.7 3.6 3.4 7.3 0.0 4.3 5 0 0 5 5 4 0 NTPase SKI PF01202.17 CCC67934.1 - 0.042 13.7 0.0 4.6 7.0 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase UPF0079 PF02367.12 CCC67934.1 - 0.053 13.1 0.1 6.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 CCC67934.1 - 0.087 11.7 0.0 3 6.6 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein DEAD PF00270.24 CCC67934.1 - 0.092 12.2 0.4 25 4.3 0.0 3.6 3 1 0 4 4 4 0 DEAD/DEAH box helicase KTI12 PF08433.5 CCC67934.1 - 0.12 11.5 0.1 12 4.9 0.0 2.7 2 1 0 2 2 2 0 Chromatin associated protein KTI12 Cyclin_N PF00134.18 CCC67935.1 - 6.2e-16 58.1 0.1 1e-15 57.4 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCC67935.1 - 5.1e-10 39.9 0.1 9e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin DUF1619 PF07773.6 CCC67936.1 - 0.14 11.9 2.6 0.25 11.1 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1619) SOBP PF15279.1 CCC67936.1 - 4 7.7 13.4 5.3 7.3 9.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein IATP PF04568.7 CCC67937.1 - 1.4e-16 60.2 1.2 1.5e-16 60.2 0.8 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Uds1 PF15456.1 CCC67937.1 - 0.018 15.0 1.2 0.023 14.6 0.9 1.2 1 0 0 1 1 1 0 Up-regulated During Septation AFG1_ATPase PF03969.11 CCC67937.1 - 0.031 13.0 0.0 0.032 13.0 0.0 1.0 1 0 0 1 1 1 0 AFG1-like ATPase DUF342 PF03961.8 CCC67937.1 - 0.069 11.5 0.7 0.066 11.6 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 CCC67937.1 - 0.11 12.1 1.1 0.11 12.0 0.7 1.1 1 0 0 1 1 1 0 IncA protein YgaB PF14182.1 CCC67937.1 - 0.14 12.4 6.7 0.17 12.1 4.7 1.2 1 0 0 1 1 1 0 YgaB-like protein Bap31 PF05529.7 CCC67937.1 - 0.2 11.0 1.9 0.25 10.7 1.3 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like DivIC PF04977.10 CCC67937.1 - 1.1 8.7 6.2 0.56 9.7 1.9 1.9 1 1 1 2 2 2 0 Septum formation initiator HMGL-like PF00682.14 CCC67938.1 - 8.5e-75 251.4 0.2 1.5e-74 250.6 0.1 1.4 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.15 CCC67938.1 - 0.038 12.5 0.0 3.9 5.9 0.0 2.4 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Cullin PF00888.17 CCC67939.1 - 1.7e-161 538.7 13.3 2.3e-161 538.3 9.2 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 CCC67939.1 - 1.6e-24 85.4 1.6 5.5e-24 83.7 0.1 2.7 3 0 0 3 3 3 1 Cullin protein neddylation domain Penicillinase_R PF03965.11 CCC67939.1 - 0.035 14.1 0.1 0.27 11.3 0.0 2.6 2 1 0 2 2 2 0 Penicillinase repressor MARVEL PF01284.18 CCC67940.1 - 0.00097 18.9 4.1 0.0017 18.1 2.9 1.3 1 0 0 1 1 1 1 Membrane-associating domain CreD PF06123.7 CCC67940.1 - 0.046 12.2 0.1 0.046 12.2 0.0 1.6 2 0 0 2 2 2 0 Inner membrane protein CreD DUF3671 PF12420.3 CCC67940.1 - 6.5 6.7 8.5 2.5 8.1 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function Ribosomal_L41 PF05162.8 CCC67941.1 - 3.4e-09 36.1 25.8 3.6e-09 36.1 17.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 DUF1601 PF07671.6 CCC67941.1 - 0.25 10.9 1.7 0.28 10.8 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1601) ATP-synt_ab PF00006.20 CCC67942.1 - 6.2e-119 395.2 0.0 1.2e-118 394.2 0.0 1.7 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Hom_end_hint PF05203.11 CCC67942.1 - 3.2e-80 268.8 0.1 5.4e-80 268.1 0.1 1.4 1 0 0 1 1 1 1 Hom_end-associated Hint Hom_end PF05204.9 CCC67942.1 - 3e-43 146.2 0.1 5.5e-39 132.5 0.0 2.4 2 0 0 2 2 2 2 Homing endonuclease ATP-synt_ab_C PF00306.22 CCC67942.1 - 1.2e-18 67.5 0.1 2.8e-18 66.4 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCC67942.1 - 1.5e-15 57.1 2.4 3.4e-15 56.0 1.6 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain LAGLIDADG_3 PF14528.1 CCC67942.1 - 6.1e-07 29.5 0.1 6.8e-06 26.2 0.1 2.4 2 0 0 2 2 2 1 LAGLIDADG-like domain Hint_2 PF13403.1 CCC67942.1 - 0.00058 19.8 0.1 0.0015 18.4 0.0 1.7 2 0 0 2 2 2 1 Hint domain Hint PF01079.15 CCC67942.1 - 0.00067 18.9 0.0 0.0016 17.7 0.0 1.6 1 0 0 1 1 1 1 Hint module AAA_14 PF13173.1 CCC67942.1 - 0.062 13.1 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain WhiA_N PF10298.4 CCC67942.1 - 0.12 12.2 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 WhiA N-terminal LAGLIDADG-like domain Metallophos PF00149.23 CCC67943.1 - 7.7e-40 136.4 0.2 1e-39 136.0 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Rho_GDI PF02115.12 CCC67944.1 - 9.7e-68 227.5 3.6 1.2e-67 227.2 2.5 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Arf PF00025.16 CCC67945.1 - 3.2e-78 260.9 0.0 3.6e-78 260.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCC67945.1 - 2.6e-14 52.9 0.0 2.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCC67945.1 - 6.2e-14 51.6 0.0 7.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCC67945.1 - 4.4e-11 42.0 0.5 4.8e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCC67945.1 - 8.8e-11 41.3 0.0 1.1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCC67945.1 - 1.5e-10 41.6 0.0 2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCC67945.1 - 8.4e-06 25.7 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCC67945.1 - 0.0057 16.1 0.0 0.027 13.8 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 CCC67945.1 - 0.006 16.0 0.2 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CCC67945.1 - 0.0069 16.2 0.1 0.011 15.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CCC67945.1 - 0.021 14.5 0.5 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 CCC67945.1 - 0.032 14.5 0.1 0.059 13.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.13 CCC67945.1 - 0.041 12.9 0.1 0.061 12.3 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DBD_Tnp_Mut PF03108.10 CCC67945.1 - 0.07 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 MuDR family transposase cobW PF02492.14 CCC67945.1 - 0.075 12.4 0.1 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Sugar_tr PF00083.19 CCC67946.1 - 1.1e-125 419.7 28.6 1.4e-125 419.4 19.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC67946.1 - 2.8e-20 72.3 31.8 2.7e-14 52.6 7.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 CCC67946.1 - 0.14 12.1 2.5 0.32 11.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Scm3 PF10384.4 CCC67947.1 - 5.7e-20 70.5 1.2 5.7e-20 70.5 0.9 1.9 2 0 0 2 2 2 1 Centromere protein Scm3 SLX9 PF15341.1 CCC67947.1 - 0.19 12.1 5.6 0.39 11.1 3.9 1.5 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 RNA_pol_Rpb1_1 PF04997.7 CCC67948.1 - 9.4e-118 393.3 0.0 1.7e-117 392.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 CCC67948.1 - 1.3e-107 359.1 0.1 2.4e-107 358.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CCC67948.1 - 2.9e-72 242.0 1.1 5.1e-72 241.2 0.0 2.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 CCC67948.1 - 1.3e-63 214.1 0.4 3e-63 212.9 0.3 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 CCC67948.1 - 9.3e-46 155.4 0.0 2.4e-45 154.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 CCC67948.1 - 2.9e-45 153.2 3.6 6e-45 152.2 2.5 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 CCC67948.1 - 2.8e-35 120.3 0.1 7.4e-35 118.9 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 CCC67948.1 - 2.9e-12 45.6 262.2 0.13 12.4 9.5 14.1 3 1 1 14 14 14 11 RNA polymerase Rpb1 C-terminal repeat DUF4123 PF13503.1 CCC67948.1 - 0.24 11.3 0.0 0.48 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) BPL_N PF09825.4 CCC67949.1 - 1.4e-124 415.6 0.0 1.7e-124 415.3 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 CCC67949.1 - 2.8e-12 46.7 0.0 2.4e-11 43.7 0.0 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 CCC67949.1 - 6.4e-10 38.5 0.0 1.1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Cpn60_TCP1 PF00118.19 CCC67950.1 - 3.4e-136 454.7 11.8 3.8e-136 454.5 8.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DeoC PF01791.4 CCC67950.1 - 0.055 12.7 1.7 1.4 8.1 0.1 3.0 3 0 0 3 3 3 0 DeoC/LacD family aldolase ApbA_C PF08546.6 CCC67951.1 - 5.4e-27 94.2 0.0 7.8e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 CCC67951.1 - 2.3e-20 72.5 0.0 3.3e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAGLU_N PF12971.2 CCC67951.1 - 0.13 11.9 0.1 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Coatomer_WDAD PF04053.9 CCC67952.1 - 1.6e-131 439.1 6.2 2.9e-131 438.3 4.3 1.4 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 CCC67952.1 - 1.8e-66 224.4 0.1 2.6e-66 223.9 0.1 1.2 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 CCC67952.1 - 5.8e-58 190.8 14.2 2.2e-11 43.1 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 CCC67952.1 - 4.4e-05 21.8 6.3 0.42 8.6 0.3 3.8 2 1 2 4 4 4 3 Nucleoporin Nup120/160 CNH PF00780.17 CCC67952.1 - 0.004 16.6 0.4 0.0092 15.4 0.1 1.8 2 0 0 2 2 2 1 CNH domain DUF2013 PF09431.5 CCC67953.1 - 6.3e-45 152.3 13.2 6.3e-45 152.3 9.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) PCI PF01399.22 CCC67954.1 - 1.2e-20 73.7 2.0 2.5e-20 72.7 0.1 2.5 2 0 0 2 2 2 1 PCI domain Nop14 PF04147.7 CCC67955.1 - 5.2e-226 752.4 81.6 2.7e-224 746.8 56.5 2.0 1 1 0 1 1 1 1 Nop14-like family APG9 PF04109.11 CCC67956.1 - 2.5e-160 533.4 9.9 3.8e-160 532.8 6.9 1.3 1 0 0 1 1 1 1 Autophagy protein Apg9 RNA_pol_Rpc4 PF05132.9 CCC67957.1 - 6.5e-33 113.5 3.7 6.5e-33 113.5 2.5 2.9 3 0 0 3 3 3 1 RNA polymerase III RPC4 Sas10 PF09368.5 CCC67958.1 - 2.2e-30 104.6 11.2 6e-30 103.2 7.7 1.8 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 CCC67958.1 - 8.2e-10 38.7 0.3 3.8e-09 36.6 0.2 2.3 1 0 0 1 1 1 1 Sas10/Utp3/C1D family MutS_V PF00488.16 CCC67959.1 - 2.7e-56 190.6 0.0 5e-56 189.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCC67959.1 - 6.6e-30 104.4 0.0 4.3e-29 101.7 0.0 2.4 2 2 0 2 2 2 1 MutS domain III PP-binding_2 PF14573.1 CCC67959.1 - 0.0059 16.6 0.3 0.037 14.0 0.1 2.4 2 0 0 2 2 2 1 Acyl-carrier AAA_14 PF13173.1 CCC67959.1 - 0.012 15.5 4.2 0.79 9.6 0.0 3.4 4 0 0 4 4 4 0 AAA domain AAA_29 PF13555.1 CCC67959.1 - 0.06 12.8 0.2 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cyclin_N PF00134.18 CCC67960.1 - 9.8e-41 138.2 0.4 9.8e-41 138.2 0.3 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCC67960.1 - 1.5e-27 95.8 0.4 1.4e-25 89.5 0.1 2.6 2 0 0 2 2 2 2 Cyclin, C-terminal domain CEP19 PF14933.1 CCC67960.1 - 0.035 14.4 3.0 0.071 13.4 2.1 1.4 1 0 0 1 1 1 0 CEP19-like protein WD40 PF00400.27 CCC67961.1 - 3.2e-10 39.5 5.8 0.00061 19.5 0.0 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase PF00069.20 CCC67963.1 - 4.3e-64 216.1 0.0 6.4e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC67963.1 - 9.7e-39 132.9 0.0 1.4e-38 132.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC67963.1 - 4.8e-05 22.4 0.0 0.0001 21.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DEAD PF00270.24 CCC67964.1 - 1.3e-41 141.9 0.1 2.6e-41 140.9 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC67964.1 - 1.2e-25 89.1 0.2 3e-25 87.8 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dynactin_p62 PF05502.8 CCC67965.1 - 0.00024 20.0 19.7 0.00024 20.0 13.7 1.9 1 1 0 2 2 2 1 Dynactin p62 family Elf1 PF05129.8 CCC67965.1 - 0.0019 17.8 4.0 0.0019 17.8 2.8 3.5 2 1 1 3 3 3 1 Transcription elongation factor Elf1 like Zn_Tnp_IS1595 PF12760.2 CCC67965.1 - 0.023 14.5 6.3 0.023 14.5 4.4 4.3 2 1 1 3 3 3 0 Transposase zinc-ribbon domain DUF4264 PF14084.1 CCC67965.1 - 0.074 12.4 0.1 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) Cys_rich_CPXG PF14255.1 CCC67965.1 - 0.17 11.7 0.3 0.17 11.7 0.2 4.5 3 1 0 4 4 4 0 Cysteine-rich CPXCG Dimer_Tnp_hAT PF05699.9 CCC67967.1 - 8.2e-09 34.9 0.2 3e-08 33.1 0.1 2.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 CCC67967.1 - 0.023 14.4 0.6 0.052 13.3 0.4 1.7 1 0 0 1 1 1 0 BED zinc finger DUF3589 PF12141.3 CCC67968.1 - 1.7e-96 323.4 2.4 7e-96 321.4 1.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) DNA_ligase_A_M PF01068.16 CCC67969.1 - 5.6e-60 202.1 0.4 8.9e-60 201.5 0.3 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CCC67969.1 - 5.5e-55 185.9 0.8 1.1e-54 184.9 0.1 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 CCC67969.1 - 2.7e-26 91.7 0.1 2.2e-25 88.8 0.0 2.5 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 CCC67969.1 - 0.0028 17.2 0.3 0.27 10.9 0.0 2.6 2 0 0 2 2 2 1 DNA ligase OB-like domain Phasin PF05597.6 CCC67969.1 - 0.073 12.8 0.1 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) zf-Mss51 PF13824.1 CCC67970.1 - 5.9e-20 70.8 0.1 1.5e-19 69.6 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.6 CCC67970.1 - 0.0028 17.1 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain NOT2_3_5 PF04153.13 CCC67971.1 - 4.7e-33 113.9 0.4 5.7e-33 113.6 0.3 1.1 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family AAA_18 PF13238.1 CCC67972.1 - 1.7e-26 93.0 0.1 1.7e-26 93.0 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCC67972.1 - 6.1e-14 52.8 1.5 1.5e-13 51.5 1.0 1.8 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CCC67972.1 - 7.1e-05 22.9 0.0 0.00019 21.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_28 PF13521.1 CCC67972.1 - 0.00012 22.1 0.1 0.0013 18.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCC67972.1 - 0.00024 21.1 0.4 0.0036 17.2 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCC67972.1 - 0.0004 20.5 0.0 0.00085 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCC67972.1 - 0.0021 17.9 0.0 0.0043 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCC67972.1 - 0.0025 17.7 0.0 0.33 10.8 0.0 2.4 1 1 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 CCC67972.1 - 0.0034 16.7 0.0 0.98 8.7 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase KTI12 PF08433.5 CCC67972.1 - 0.0049 16.1 0.0 0.02 14.1 0.0 1.9 1 1 1 2 2 2 1 Chromatin associated protein KTI12 Rad17 PF03215.10 CCC67972.1 - 0.005 15.5 0.0 0.0062 15.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 CCC67972.1 - 0.0054 16.4 0.0 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CCC67972.1 - 0.0087 16.2 0.0 0.018 15.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.17 CCC67972.1 - 0.01 15.7 0.1 0.58 10.0 0.0 2.3 2 1 0 2 2 2 0 Adenylate kinase Mg_chelatase PF01078.16 CCC67972.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CCC67972.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 CCC67972.1 - 0.025 14.3 0.0 0.04 13.6 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 CCC67972.1 - 0.027 14.7 0.8 0.091 13.0 0.6 2.0 1 1 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 CCC67972.1 - 0.032 13.9 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_10 PF12846.2 CCC67972.1 - 0.044 13.2 0.0 0.074 12.4 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Viral_helicase1 PF01443.13 CCC67972.1 - 0.052 13.0 0.0 0.08 12.4 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase FtsK_SpoIIIE PF01580.13 CCC67972.1 - 0.062 12.7 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 CCC67972.1 - 0.07 12.6 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArgK PF03308.11 CCC67972.1 - 0.092 11.4 0.0 0.18 10.5 0.0 1.4 1 0 0 1 1 1 0 ArgK protein zf-RanBP PF00641.13 CCC67973.1 - 2e-21 74.7 12.8 5.2e-11 41.4 2.1 2.7 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 CCC67973.1 - 1.4e-08 34.1 0.0 0.0014 18.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC67973.1 - 0.0035 17.2 0.0 0.044 13.7 0.0 2.5 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 CCC67973.1 - 0.015 15.0 7.7 0.58 10.0 0.9 2.4 2 0 0 2 2 2 0 Double zinc ribbon Rubredoxin PF00301.15 CCC67973.1 - 0.06 13.2 6.2 0.95 9.3 0.3 2.7 2 0 0 2 2 2 0 Rubredoxin DUF765 PF05570.6 CCC67973.1 - 0.91 9.5 4.4 0.31 11.0 0.6 2.2 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) ADH_N PF08240.7 CCC67974.1 - 9.6e-28 96.1 3.1 9.6e-28 96.1 2.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCC67974.1 - 2e-18 66.1 0.1 3.9e-18 65.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCC67974.1 - 0.0047 16.0 0.1 0.0083 15.3 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CCC67974.1 - 0.02 14.2 0.1 0.036 13.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ELFV_dehydrog PF00208.16 CCC67974.1 - 0.044 13.3 2.1 0.079 12.5 1.4 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 CCC67974.1 - 0.051 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_7 PF13241.1 CCC67974.1 - 0.12 12.6 0.1 0.24 11.6 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Nop PF01798.13 CCC67975.1 - 2e-60 202.4 0.1 4.5e-60 201.2 0.1 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 CCC67975.1 - 8.8e-27 92.6 0.1 1.9e-26 91.6 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CCC67975.1 - 2.1e-24 85.4 0.3 2.1e-24 85.4 0.2 2.8 2 1 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 CCC67975.1 - 0.13 11.9 54.9 0.25 11.0 38.1 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 GAGA_bind PF06217.7 CCC67975.1 - 0.38 10.6 22.5 0.58 10.0 15.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CCC67975.1 - 1.1 9.1 31.9 1.8 8.3 22.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Zip PF02535.17 CCC67975.1 - 2.5 7.0 9.2 3.5 6.5 6.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Glu_synthase PF01645.12 CCC67977.1 - 1.2e-154 514.7 0.1 2.4e-154 513.7 0.0 1.6 2 0 0 2 2 2 1 Conserved region in glutamate synthase GATase_2 PF00310.16 CCC67977.1 - 6.9e-137 455.9 0.0 4.3e-136 453.3 0.0 2.0 2 0 0 2 2 2 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 CCC67977.1 - 1.8e-114 381.8 0.0 4e-114 380.7 0.0 1.6 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 CCC67977.1 - 8.8e-59 197.8 3.0 1.5e-58 197.1 2.1 1.3 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 CCC67977.1 - 4.1e-24 84.3 0.1 8.7e-24 83.2 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 CCC67977.1 - 1.7e-15 57.4 0.0 4.6e-15 56.0 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCC67977.1 - 3.9e-11 43.4 0.1 3.3e-05 24.0 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCC67977.1 - 5.8e-09 35.8 0.0 1.6e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCC67977.1 - 6.4e-07 29.6 0.3 0.00012 22.3 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCC67977.1 - 1.6e-05 23.5 4.1 2.3e-05 23.0 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein DAO PF01266.19 CCC67977.1 - 2.1e-05 23.6 0.0 0.00011 21.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 CCC67977.1 - 2.1e-05 24.2 0.0 4.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Amino_oxidase PF01593.19 CCC67977.1 - 7e-05 22.0 0.0 0.00013 21.1 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 CCC67977.1 - 0.00016 20.6 0.0 0.00028 19.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 CCC67977.1 - 0.00063 18.9 0.2 0.0021 17.2 0.0 1.9 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 CCC67977.1 - 0.0024 16.9 0.0 0.0062 15.6 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 CCC67977.1 - 0.0047 17.1 0.1 1.2 9.4 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding GATase_6 PF13522.1 CCC67977.1 - 0.0058 16.5 0.0 0.025 14.5 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain FAD_binding_3 PF01494.14 CCC67977.1 - 0.0095 15.0 0.0 0.02 13.9 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_10 PF13460.1 CCC67977.1 - 0.016 15.2 0.1 0.14 12.1 0.0 2.5 1 1 1 2 2 2 0 NADH(P)-binding Shikimate_DH PF01488.15 CCC67977.1 - 0.017 15.2 1.8 2.5 8.2 0.0 2.9 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 CCC67977.1 - 0.025 14.3 0.1 0.43 10.3 0.0 3.1 4 0 0 4 4 3 0 FAD-NAD(P)-binding IlvN PF07991.7 CCC67977.1 - 0.036 13.4 0.1 0.16 11.3 0.0 2.2 2 0 0 2 2 1 0 Acetohydroxy acid isomeroreductase, catalytic domain 2-Hacid_dh_C PF02826.14 CCC67977.1 - 0.038 13.1 0.0 1.3 8.1 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CCC67977.1 - 0.043 14.2 0.3 0.27 11.6 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 CCC67977.1 - 0.052 13.3 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.17 CCC67977.1 - 0.08 11.7 2.0 0.17 10.7 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A Mit_ribos_Mrp51 PF11709.3 CCC67977.1 - 0.11 11.6 1.4 0.21 10.7 1.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit 3HCDH_N PF02737.13 CCC67977.1 - 0.14 11.7 0.0 0.68 9.5 0.0 2.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 CCC67977.1 - 1.3 8.8 5.3 19 5.0 0.1 2.9 2 1 0 3 3 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF3602 PF12223.3 CCC67978.1 - 1.3e-19 70.3 8.1 2.4e-12 47.0 0.1 3.4 2 1 1 3 3 3 3 Protein of unknown function (DUF3602) FAD-oxidase_C PF02913.14 CCC67979.1 - 9.6e-58 195.4 0.0 1.3e-57 194.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCC67979.1 - 1.5e-34 118.4 0.0 2.9e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Vinculin PF01044.14 CCC67979.1 - 0.069 11.1 0.0 0.099 10.6 0.0 1.2 1 0 0 1 1 1 0 Vinculin family PALP PF00291.20 CCC67981.1 - 3.6e-73 246.4 0.2 5e-73 246.0 0.2 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 CCC67981.1 - 1.7e-42 142.8 0.0 6.7e-28 96.1 0.0 2.6 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase ACT PF01842.20 CCC67981.1 - 0.11 12.0 0.1 9.9 5.7 0.0 3.0 3 0 0 3 3 3 0 ACT domain TPP_enzyme_N PF02776.13 CCC67982.1 - 9.7e-34 116.3 0.0 1.5e-33 115.6 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCC67982.1 - 1.9e-31 108.6 0.0 6.6e-31 106.8 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCC67982.1 - 1.3e-15 57.3 0.0 2.3e-15 56.4 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 CCC67982.1 - 0.024 14.1 0.0 0.074 12.6 0.0 1.8 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit tRNA-synt_2b PF00587.20 CCC67983.1 - 1.2e-30 106.3 0.0 2.2e-30 105.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Sec61_beta PF03911.11 CCC67984.1 - 1e-08 34.7 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Sec61beta family Cas_Csx9 PF09658.5 CCC67984.1 - 0.032 13.0 0.0 0.034 12.9 0.0 1.0 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csx9) RRM_6 PF14259.1 CCC67985.1 - 7.2e-09 35.5 0.0 1.5e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCC67985.1 - 7.4e-08 31.9 0.0 1.7e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC67985.1 - 0.00025 20.8 0.0 0.00056 19.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Myb_DNA-bind_6 PF13921.1 CCC67986.1 - 4.8e-12 45.7 7.0 9.7e-11 41.6 0.3 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCC67986.1 - 3.5e-09 36.5 2.0 3.4e-07 30.2 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Phospholip_A2_2 PF05826.7 CCC67986.1 - 0.03 14.2 0.1 0.081 12.8 0.1 1.7 1 0 0 1 1 1 0 Phospholipase A2 PP2C PF00481.16 CCC67987.1 - 2.7e-82 276.0 0.0 3.4e-82 275.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Chorismate_bind PF00425.13 CCC67988.1 - 2e-87 292.7 0.0 3.3e-87 292.0 0.0 1.3 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 CCC67988.1 - 1.5e-30 106.0 0.1 1.1e-28 100.0 0.0 3.0 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region POR PF01558.13 CCC67988.1 - 0.013 15.4 0.0 0.047 13.5 0.0 1.9 3 0 0 3 3 3 0 Pyruvate ferredoxin/flavodoxin oxidoreductase Meth_synt_2 PF01717.13 CCC67989.1 - 5e-140 466.0 0.0 1.2e-136 455.0 0.0 2.6 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 CCC67989.1 - 2.7e-126 421.0 1.0 1.1e-113 379.6 0.0 3.8 4 0 0 4 4 4 3 Cobalamin-independent synthase, N-terminal domain HALZ PF02183.13 CCC67990.1 - 0.044 13.5 1.2 0.1 12.3 0.8 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Med21 PF11221.3 CCC67990.1 - 0.11 12.4 2.3 0.23 11.4 0.3 1.9 2 0 0 2 2 2 0 Subunit 21 of Mediator complex DUF904 PF06005.7 CCC67990.1 - 0.67 10.2 3.7 1.3 9.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TBPIP PF07106.8 CCC67990.1 - 1.1 8.8 5.6 2.6 7.5 3.9 1.6 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RICTOR_N PF14664.1 CCC67991.1 - 2.5e-100 335.6 11.6 9.4e-100 333.7 8.0 1.9 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 CCC67991.1 - 4.4e-76 254.8 2.0 4.4e-76 254.8 1.4 4.8 5 0 0 5 5 5 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 CCC67991.1 - 3.1e-30 104.4 2.8 8.4e-30 103.0 0.4 2.9 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 CCC67991.1 - 4.6e-29 100.1 0.9 2.2e-27 94.7 0.2 3.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 Amdo_NSP PF12475.3 CCC67991.1 - 0.6 10.0 4.8 0.36 10.7 1.6 2.0 2 0 0 2 2 2 0 Amdovirus non-structural protein IncA PF04156.9 CCC67991.1 - 1.2 8.6 16.2 0.091 12.3 7.2 2.2 2 0 0 2 2 2 0 IncA protein DoxX PF07681.7 CCC67992.1 - 0.017 15.4 0.9 0.026 14.9 0.6 1.2 1 0 0 1 1 1 0 DoxX Proteasome PF00227.21 CCC67993.1 - 3.7e-41 140.5 0.0 4.5e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Rad51 PF08423.6 CCC67994.1 - 1.1e-137 456.9 0.0 1.5e-137 456.6 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CCC67994.1 - 2.8e-14 52.9 0.0 4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 CCC67994.1 - 1.6e-12 47.3 1.2 2.4e-12 46.8 0.2 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 CCC67994.1 - 2.8e-12 46.3 0.0 4e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 CCC67994.1 - 6.5e-07 28.6 0.0 1.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 KaiC AAA_22 PF13401.1 CCC67994.1 - 0.0077 16.3 0.0 0.015 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DnaB_C PF03796.10 CCC67994.1 - 0.046 12.6 0.0 0.087 11.6 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 CCC67994.1 - 0.12 11.2 0.1 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 PAXNEB protein HHH PF00633.18 CCC67994.1 - 0.13 12.0 0.1 0.34 10.7 0.1 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif UCH PF00443.24 CCC67995.1 - 8.6e-79 264.4 14.8 8.6e-79 264.4 10.3 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC67995.1 - 3.7e-24 85.6 3.0 3.2e-22 79.3 0.1 3.3 3 1 1 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase Ecl1 PF12855.2 CCC67995.1 - 0.023 13.9 1.5 0.063 12.5 1.0 1.8 1 0 0 1 1 1 0 Life-span regulatory factor Pribosyltran_N PF13793.1 CCC67996.1 - 1.7e-44 150.2 0.0 2.2e-42 143.4 0.0 2.2 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 CCC67996.1 - 4.8e-37 127.4 0.7 2.4e-30 105.6 0.2 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 CCC67996.1 - 1.2e-12 47.5 1.7 1.3e-11 44.3 0.3 2.5 3 0 0 3 3 3 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCC67996.1 - 0.0032 16.6 0.1 0.0049 16.0 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase UQ_con PF00179.21 CCC67997.1 - 9.5e-27 93.1 0.1 1.4e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCC67997.1 - 0.012 15.4 0.7 0.02 14.8 0.1 1.7 2 1 0 2 2 2 0 RWD domain ADH_zinc_N_2 PF13602.1 CCC67998.1 - 5e-11 43.6 0.0 8.5e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCC67998.1 - 0.033 13.9 0.1 0.066 12.9 0.1 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain zf-CSL PF05207.8 CCC67999.1 - 4.4e-22 77.3 0.9 6.6e-22 76.7 0.6 1.3 1 0 0 1 1 1 1 CSL zinc finger Ribosomal_S8e PF01201.17 CCC68000.1 - 3.3e-50 169.6 2.6 3.8e-50 169.4 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e AAR2 PF05282.6 CCC68001.1 - 7.1e-58 196.2 14.3 8.9e-58 195.9 9.9 1.2 1 0 0 1 1 1 1 AAR2 protein HSP70 PF00012.15 CCC68002.1 - 1e-269 895.6 8.8 1.2e-269 895.4 6.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCC68002.1 - 5e-16 58.1 0.0 8e-15 54.2 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CCC68002.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CCC68002.1 - 0.0098 14.7 1.0 0.62 8.8 0.2 2.3 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CCC68002.1 - 0.036 13.1 1.9 0.079 12.0 0.0 2.4 2 1 0 3 3 3 0 Hydantoinase/oxoprolinase MAM1 PF10434.4 CCC68004.1 - 2.7e-35 121.9 10.8 1.5e-34 119.4 7.5 1.9 1 1 0 1 1 1 1 Monopolin complex protein MAM1 WD40 PF00400.27 CCC68005.1 - 6e-27 92.5 8.9 6.2e-07 29.0 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat Nup160 PF11715.3 CCC68005.1 - 0.002 16.3 0.3 0.011 13.8 0.0 1.9 2 0 0 2 2 2 1 Nucleoporin Nup120/160 LisH PF08513.6 CCC68006.1 - 1.8e-05 24.3 0.0 3.8e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 LisH Aft1_HRR PF11787.3 CCC68006.1 - 3.3 8.8 8.3 0.36 11.9 0.3 3.1 3 0 0 3 3 3 0 Aft1 HRR domain HEAT_EZ PF13513.1 CCC68007.1 - 2.1e-18 66.2 2.4 0.0072 16.7 0.0 9.0 9 1 1 10 10 10 4 HEAT-like repeat HEAT PF02985.17 CCC68007.1 - 5e-15 54.1 2.4 0.013 15.5 0.0 9.4 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 CCC68007.1 - 8.6e-14 51.5 7.6 0.011 15.9 0.3 7.3 5 2 1 6 6 6 3 HEAT repeats IBN_N PF03810.14 CCC68007.1 - 7.6e-12 44.9 6.6 2.3e-08 33.7 0.3 4.4 4 0 0 4 4 4 2 Importin-beta N-terminal domain Ipi1_N PF12333.3 CCC68007.1 - 0.0014 18.5 0.2 8.2 6.4 0.0 5.6 5 1 1 6 6 6 1 Rix1 complex component involved in 60S ribosome maturation Cnd1 PF12717.2 CCC68007.1 - 0.0044 16.8 6.0 0.067 13.0 0.0 4.8 3 2 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Ank_2 PF12796.2 CCC68008.1 - 7.3e-11 42.2 0.8 0.00066 19.9 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCC68008.1 - 7.8e-09 35.8 3.4 0.0089 16.5 0.2 4.4 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 CCC68008.1 - 2.3e-08 33.4 6.8 0.0022 17.7 0.5 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 CCC68008.1 - 3.5e-08 33.4 3.1 0.0018 18.4 0.1 3.6 3 1 1 4 4 4 2 Ankyrin repeats (many copies) KilA-N PF04383.8 CCC68008.1 - 1.9e-06 27.4 0.1 1.9e-06 27.4 0.1 2.8 2 1 0 2 2 2 1 KilA-N domain Ank_3 PF13606.1 CCC68008.1 - 4.4e-06 26.4 4.2 0.15 12.3 0.2 4.2 4 0 0 4 4 4 2 Ankyrin repeat LSM PF01423.17 CCC68009.1 - 3.2e-16 58.6 0.4 5.5e-16 57.8 0.3 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 CCC68009.1 - 1.3e-05 25.0 0.0 2.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain EMP70 PF02990.11 CCC68010.1 - 1.8e-142 475.4 16.4 2.6e-142 474.9 11.3 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 VIT1 PF01988.14 CCC68010.1 - 0.029 13.8 0.2 0.029 13.8 0.1 3.1 4 0 0 4 4 4 0 VIT family Consortin_C PF15281.1 CCC68010.1 - 1.5 8.3 4.9 17 4.9 0.1 3.9 4 0 0 4 4 4 0 Consortin C-terminus PH PF00169.24 CCC68011.1 - 4.8e-14 52.4 3.8 9.2e-14 51.5 0.0 3.1 2 1 0 2 2 2 1 PH domain SAM_2 PF07647.12 CCC68011.1 - 6.1e-12 45.2 0.0 1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 CCC68011.1 - 6.6e-12 44.6 0.6 1.8e-11 43.2 0.1 2.0 2 0 0 2 2 2 1 SH3 domain PH_11 PF15413.1 CCC68011.1 - 1.9e-11 44.1 0.2 2.3e-10 40.7 0.0 3.0 2 0 0 2 2 2 1 Pleckstrin homology domain SH3_9 PF14604.1 CCC68011.1 - 4e-08 32.7 0.1 8.3e-08 31.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 CCC68011.1 - 3.4e-07 30.2 0.0 2.4e-05 24.2 0.0 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain SAM_1 PF00536.25 CCC68011.1 - 0.00037 20.5 0.0 0.00065 19.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 CCC68011.1 - 0.0021 17.5 0.0 0.0051 16.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SAM_PNT PF02198.11 CCC68011.1 - 0.039 13.7 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain DUF4515 PF14988.1 CCC68012.1 - 0.071 12.7 0.2 0.1 12.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4515) zf-C3HC4 PF00097.20 CCC68013.1 - 4.9e-09 35.6 10.4 8.1e-09 35.0 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCC68013.1 - 5.5e-09 35.5 9.5 8.1e-09 35.0 6.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCC68013.1 - 1e-08 34.8 11.2 1.6e-08 34.2 7.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCC68013.1 - 2.2e-06 27.5 11.3 3.9e-06 26.7 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCC68013.1 - 6.8e-06 25.7 7.0 1.3e-05 24.7 4.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 CCC68013.1 - 3.5e-05 23.4 10.3 5.6e-05 22.7 7.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCC68013.1 - 0.0026 17.5 11.4 0.0043 16.8 7.9 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FYVE_2 PF02318.11 CCC68013.1 - 0.0082 16.0 1.1 0.016 15.1 0.8 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger zf-Apc11 PF12861.2 CCC68013.1 - 0.017 14.9 3.4 0.028 14.2 2.4 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CCC68013.1 - 0.1 12.6 5.0 0.22 11.6 3.4 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 CCC68013.1 - 0.2 11.2 10.8 0.95 9.0 7.6 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-MIZ PF02891.15 CCC68013.1 - 2.9 7.4 9.4 7.2 6.2 6.5 1.7 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger PBP1_TM PF14812.1 CCC68013.1 - 9.4 6.6 7.5 2.3 8.5 2.6 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ribosomal_L14 PF00238.14 CCC68014.1 - 5.1e-31 106.9 0.0 5.7e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e SH3_1 PF00018.23 CCC68015.1 - 1.1e-13 50.2 0.2 2.5e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCC68015.1 - 2.7e-11 42.8 0.1 5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCC68015.1 - 8.2e-10 38.0 0.0 1.5e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Ribosomal_S21 PF01165.15 CCC68016.1 - 2.7e-12 45.9 1.3 5.8e-12 44.8 0.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 Peptidase_M24 PF00557.19 CCC68017.1 - 4.5e-51 173.3 0.1 5.7e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 DUF3349 PF11829.3 CCC68017.1 - 0.22 11.9 0.9 41 4.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3349) Motile_Sperm PF00635.21 CCC68018.1 - 2.3e-25 88.3 0.1 2.3e-25 88.3 0.1 2.1 2 2 0 2 2 2 1 MSP (Major sperm protein) domain PapD-like PF14874.1 CCC68018.1 - 0.021 14.7 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Flagellar-associated PapD-like Mem_trans PF03547.13 CCC68018.1 - 1.4 7.1 5.2 2 6.6 3.6 1.2 1 0 0 1 1 1 0 Membrane transport protein GAGA_bind PF06217.7 CCC68018.1 - 6.8 6.5 9.0 9.7 6.0 6.2 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Ribosomal_L32e PF01655.13 CCC68019.1 - 6e-46 155.0 1.7 7e-46 154.8 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF3437 PF11919.3 CCC68019.1 - 0.15 11.8 0.3 0.28 10.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) ArfGap PF01412.13 CCC68020.1 - 3.2e-33 113.9 1.2 3.2e-33 113.9 0.8 2.5 3 1 0 3 3 3 1 Putative GTPase activating protein for Arf DUF2638 PF10937.3 CCC68020.1 - 7.7 7.5 8.5 3.2 8.8 0.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2638) TPP_enzyme_M PF00205.17 CCC68021.1 - 2.2e-34 118.1 0.0 8.2e-34 116.3 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N PF02776.13 CCC68021.1 - 1.5e-32 112.4 0.0 2.2e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCC68021.1 - 1.1e-13 51.0 0.0 2.5e-13 49.8 0.0 1.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Peptidase_M41 PF01434.13 CCC68022.1 - 3.5e-70 235.8 0.2 5.6e-70 235.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 CCC68022.1 - 1.6e-40 138.3 0.0 3.2e-40 137.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCC68022.1 - 9.2e-06 25.8 0.1 0.0065 16.6 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC68022.1 - 2.3e-05 24.4 0.1 8.6e-05 22.6 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CCC68022.1 - 0.00037 19.9 1.1 0.057 12.8 0.3 2.4 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 CCC68022.1 - 0.00047 20.9 0.0 0.0013 19.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CCC68022.1 - 0.00056 18.7 0.0 0.00093 18.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 CCC68022.1 - 0.0014 17.7 0.0 0.0045 16.0 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 CCC68022.1 - 0.0015 18.2 0.1 0.0067 16.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCC68022.1 - 0.0025 17.5 2.3 0.0077 15.9 1.6 1.8 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 CCC68022.1 - 0.0047 16.3 0.0 0.0099 15.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCC68022.1 - 0.0074 16.1 0.0 0.061 13.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCC68022.1 - 0.018 15.3 0.1 0.068 13.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 CCC68022.1 - 0.025 13.6 0.1 0.056 12.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin KaiC PF06745.8 CCC68022.1 - 0.029 13.5 0.1 0.45 9.6 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_33 PF13671.1 CCC68022.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 CCC68022.1 - 0.044 12.9 0.2 0.098 11.8 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 CCC68022.1 - 0.087 12.0 0.7 0.3 10.2 0.2 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_2 PF07724.9 CCC68022.1 - 0.092 12.6 0.0 0.28 11.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_28 PF13521.1 CCC68022.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cyclin_N PF00134.18 CCC68023.1 - 2e-11 43.5 0.5 4.5e-11 42.4 0.3 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 CCC68023.1 - 0.028 14.2 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Glyco_hydro_65m PF03632.10 CCC68024.1 - 3.3e-100 335.3 2.7 1.7e-99 333.0 1.9 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain Glyco_hydro_65N PF03636.10 CCC68024.1 - 9e-44 149.6 0.0 1.6e-43 148.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65C PF03633.10 CCC68024.1 - 3.1e-12 46.3 0.6 8.6e-12 44.9 0.1 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 65, C-terminal domain TB2_DP1_HVA22 PF03134.14 CCC68025.1 - 1.1e-29 101.9 2.9 1.5e-29 101.5 2.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Adaptin_N PF01602.15 CCC68026.1 - 1.9e-80 270.6 39.7 3.4e-80 269.8 27.5 1.4 1 1 0 1 1 1 1 Adaptin N terminal region Arrestin_N PF00339.24 CCC68027.1 - 4.5e-05 23.2 0.1 0.00036 20.3 0.0 2.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain zf-HC5HC2H_2 PF13832.1 CCC68028.1 - 3.5e-30 104.2 7.2 3.5e-30 104.2 5.0 2.3 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 CCC68028.1 - 3.2e-28 97.7 5.5 3.2e-28 97.7 3.8 3.0 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 CCC68028.1 - 4.4e-13 48.2 3.0 4.4e-13 48.2 2.1 3.1 3 0 0 3 3 3 1 PHD-finger PHD PF00628.24 CCC68028.1 - 2.6e-08 33.4 19.2 4.7e-08 32.6 2.9 2.7 2 0 0 2 2 2 2 PHD-finger EPL1 PF10513.4 CCC68028.1 - 3.7e-08 33.7 1.2 3.7e-08 33.7 0.8 2.6 2 1 0 2 2 2 1 Enhancer of polycomb-like zf-RING-like PF08746.6 CCC68028.1 - 0.082 12.9 21.7 0.76 9.8 6.0 2.8 2 0 0 2 2 2 0 RING-like domain GTA_TIM PF13547.1 CCC68028.1 - 0.091 11.7 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 GTA TIM-barrel-like domain zf-PHD-like PF15446.1 CCC68028.1 - 2.3 7.5 11.7 0.023 14.0 1.3 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain tRNA-synt_His PF13393.1 CCC68029.1 - 3.7e-39 134.6 0.0 4.9e-38 130.9 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 CCC68029.1 - 1.7e-19 70.0 0.0 7.1e-19 68.0 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCC68029.1 - 6e-12 45.3 0.0 1.2e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 CCC68029.1 - 0.00093 18.0 0.0 0.056 12.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CCC68029.1 - 0.041 13.0 0.0 0.074 12.2 0.0 1.4 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Actin PF00022.14 CCC68030.1 - 4.1e-53 180.2 1.2 2.1e-38 131.7 0.1 2.2 2 0 0 2 2 2 2 Actin Rotamase_2 PF13145.1 CCC68030.1 - 0.058 14.0 1.1 0.1 13.2 0.8 1.5 1 0 0 1 1 1 0 PPIC-type PPIASE domain Ndc1_Nup PF09531.5 CCC68030.1 - 0.092 11.1 0.8 3.3 6.0 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Gln-synt_C PF00120.19 CCC68031.1 - 1.2e-66 224.4 0.0 1.5e-66 224.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 CCC68031.1 - 8.1e-20 70.1 0.0 1.4e-19 69.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain V-ATPase_H_N PF03224.9 CCC68032.1 - 4.8e-54 183.5 6.8 4.8e-54 183.5 4.7 1.8 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 CCC68032.1 - 1.7e-38 131.1 4.0 4e-38 129.9 0.3 3.0 3 0 0 3 3 3 1 V-ATPase subunit H Ribosomal_L50 PF10501.4 CCC68032.1 - 0.034 14.0 0.0 3.2 7.7 0.0 2.7 2 0 0 2 2 2 0 Ribosomal subunit 39S Evr1_Alr PF04777.8 CCC68033.1 - 8.6e-15 54.4 0.0 1.5e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Erv1 / Alr family TMEM223 PF14640.1 CCC68033.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane protein 223 TIP41 PF04176.8 CCC68034.1 - 3e-69 231.8 4.8 5.1e-69 231.1 3.3 1.4 1 0 0 1 1 1 1 TIP41-like family DUF4292 PF14125.1 CCC68034.1 - 0.0014 18.0 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4292) TPR_2 PF07719.12 CCC68035.1 - 1e-06 28.1 0.2 8.4e-06 25.3 0.0 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCC68035.1 - 5.4e-06 25.8 0.7 4e-05 23.0 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCC68035.1 - 0.00011 21.7 0.6 0.00078 19.0 0.1 2.3 2 1 0 2 2 2 1 TPR repeat TPR_1 PF00515.23 CCC68035.1 - 0.00011 21.6 0.0 0.00036 20.0 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCC68035.1 - 0.00098 19.5 0.0 0.012 16.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 CCC68035.1 - 0.0023 18.2 1.4 2.1 8.9 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCC68035.1 - 0.0053 17.3 0.0 0.045 14.4 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCC68035.1 - 0.0072 16.0 0.1 0.18 11.7 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCC68035.1 - 0.021 14.7 0.1 0.76 9.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CCC68035.1 - 0.051 13.7 0.3 1.4 9.0 0.0 2.7 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CCC68035.1 - 0.096 12.9 0.1 4.1 7.8 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4004 PF13171.1 CCC68035.1 - 0.49 10.5 6.5 0.13 12.4 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4004) eIF-5_eIF-2B PF01873.12 CCC68036.1 - 1.3e-42 144.4 0.0 2.4e-42 143.5 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 CCC68036.1 - 2.7e-27 94.5 0.5 3.4e-26 90.9 0.0 2.6 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon PUF PF00806.14 CCC68037.1 - 1.5e-26 90.3 5.2 3.7e-05 22.9 0.0 6.6 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 CCC68037.1 - 0.00013 21.5 0.0 0.0003 20.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC68037.1 - 0.00018 21.2 0.0 0.00048 19.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Anillin PF08174.6 CCC68038.1 - 5.9e-06 26.3 2.9 7.6e-06 26.0 0.1 2.7 2 0 0 2 2 2 1 Cell division protein anillin Ribosomal_L37ae PF01780.14 CCC68039.1 - 1.8e-38 130.2 10.5 2e-38 130.0 7.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rep_fac-A_C PF08646.5 CCC68039.1 - 0.042 13.5 1.1 0.048 13.3 0.7 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain DUF1364 PF07102.7 CCC68039.1 - 0.061 13.2 1.7 0.078 12.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Lar_restr_allev PF14354.1 CCC68039.1 - 0.086 13.1 0.9 0.13 12.5 0.6 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-C4_ClpX PF06689.8 CCC68039.1 - 0.25 10.9 5.3 1.4 8.5 3.7 2.1 1 1 0 1 1 1 0 ClpX C4-type zinc finger Zn_Tnp_IS1595 PF12760.2 CCC68039.1 - 0.32 10.8 5.2 0.53 10.1 3.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain YyzF PF14116.1 CCC68039.1 - 0.44 10.5 0.2 0.44 10.5 0.1 1.8 2 0 0 2 2 2 0 YyzF-like protein Elf1 PF05129.8 CCC68039.1 - 0.87 9.3 4.1 2.2 8.0 2.9 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like CarbpepA_inh PF02977.10 CCC68039.1 - 1.2 8.8 7.1 10 5.7 4.9 2.1 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor PX PF00787.19 CCC68040.1 - 0.00054 19.7 0.1 0.00093 18.9 0.0 1.4 1 0 0 1 1 1 1 PX domain CHORD PF04968.7 CCC68040.1 - 0.037 14.2 0.1 0.073 13.3 0.1 1.4 1 0 0 1 1 1 0 CHORD CTP_synth_N PF06418.9 CCC68043.1 - 1.3e-120 401.7 0.5 1.7e-120 401.2 0.3 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 CCC68043.1 - 4.3e-58 195.9 0.0 6.4e-58 195.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCC68043.1 - 8.3e-05 22.1 0.1 0.00027 20.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 CCC68043.1 - 0.00072 19.0 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain FixP_N PF14715.1 CCC68044.1 - 0.018 14.4 0.1 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP AMMECR1 PF01871.12 CCC68044.1 - 0.031 13.3 0.0 0.032 13.3 0.0 1.0 1 0 0 1 1 1 0 AMMECR1 ER_lumen_recept PF00810.13 CCC68045.1 - 3.9e-49 166.9 12.5 5.6e-49 166.4 8.7 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor DUF2061 PF09834.4 CCC68045.1 - 0.039 14.1 0.4 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) Proteasome PF00227.21 CCC68046.1 - 1.8e-36 125.2 0.1 1.4e-35 122.2 0.1 1.9 1 1 0 1 1 1 1 Proteasome subunit Transp_cyt_pur PF02133.10 CCC68047.1 - 6.3e-155 516.0 42.1 7.4e-155 515.8 29.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin BUD22 PF09073.5 CCC68048.1 - 0.54 9.2 23.9 0.84 8.6 16.6 1.3 1 0 0 1 1 1 0 BUD22 Peptidase_M16_C PF05193.16 CCC68049.1 - 1e-27 97.0 0.2 2.9e-27 95.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCC68049.1 - 1.1e-23 83.6 0.9 1.8e-23 82.9 0.6 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PPP4R2 PF09184.6 CCC68050.1 - 2.5e-51 174.9 13.7 2.5e-51 174.9 9.5 2.1 2 0 0 2 2 2 1 PPP4R2 VanZ PF04892.7 CCC68051.1 - 3.8e-08 33.3 0.3 5.5e-08 32.8 0.2 1.3 1 0 0 1 1 1 1 VanZ like family EF-hand_4 PF12763.2 CCC68052.1 - 1.3e-31 108.4 0.2 7.9e-11 41.6 0.3 4.0 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CCC68052.1 - 2.5e-09 37.1 0.7 0.05 13.7 0.1 5.0 4 1 0 5 5 5 2 EF-hand domain pair UBA PF00627.26 CCC68052.1 - 4.1e-09 36.0 0.2 1.5e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 UBA/TS-N domain EF-hand_1 PF00036.27 CCC68052.1 - 4.7e-09 34.8 0.1 0.019 14.2 0.0 4.2 4 0 0 4 4 3 2 EF hand EF-hand_6 PF13405.1 CCC68052.1 - 3.2e-08 32.7 0.1 0.59 10.1 0.0 4.8 4 0 0 4 4 4 3 EF-hand domain CENP-F_leu_zip PF10473.4 CCC68052.1 - 0.00024 20.9 25.7 0.00024 20.9 17.8 3.1 2 1 1 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UBA_4 PF14555.1 CCC68052.1 - 0.00028 20.3 0.4 0.00096 18.6 0.3 2.0 1 0 0 1 1 1 1 UBA-like domain DUF3584 PF12128.3 CCC68052.1 - 0.0095 13.3 49.5 0.015 12.6 34.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) EF-hand_8 PF13833.1 CCC68052.1 - 0.014 15.0 0.0 15 5.2 0.0 4.0 3 0 0 3 3 3 0 EF-hand domain pair IncA PF04156.9 CCC68052.1 - 0.049 13.2 56.7 1.1 8.8 11.7 3.7 1 1 3 4 4 4 0 IncA protein Cast PF10174.4 CCC68052.1 - 0.17 9.9 52.5 0.43 8.5 36.4 1.7 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone ADIP PF11559.3 CCC68052.1 - 1.4 8.8 59.3 1.1 9.1 12.3 3.8 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding WEMBL PF05701.6 CCC68052.1 - 6.7 5.0 50.9 28 3.0 34.2 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light TPR_MLP1_2 PF07926.7 CCC68052.1 - 7.4 6.3 62.5 0.41 10.4 13.7 4.8 1 1 3 4 4 4 0 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.15 CCC68052.1 - 9.5 5.2 50.1 5.9 5.9 10.8 2.7 1 1 1 2 2 2 0 Tropomyosin CMD PF02627.15 CCC68053.1 - 6.4e-05 22.7 0.0 0.00051 19.8 0.0 2.3 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family Yippee-Mis18 PF03226.9 CCC68054.1 - 2.8e-16 59.3 4.1 4e-16 58.8 2.9 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4451 PF14616.1 CCC68054.1 - 0.23 11.2 3.5 0.91 9.2 2.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) G-alpha PF00503.15 CCC68055.1 - 9.2e-117 390.0 12.8 1.3e-116 389.4 8.9 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCC68055.1 - 4.1e-15 55.4 0.2 3.5e-09 36.1 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCC68055.1 - 3.6e-05 23.0 1.1 0.005 15.9 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 CCC68055.1 - 0.0063 16.0 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 CCC68055.1 - 0.015 14.7 0.0 0.1 12.0 0.0 2.1 2 1 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 CCC68055.1 - 0.018 15.5 2.8 1.6 9.2 0.1 3.1 3 1 0 3 3 3 0 Miro-like protein Med17 PF10156.4 CCC68056.1 - 2.8e-129 431.4 13.3 3.7e-129 431.0 9.2 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex P5CR_dimer PF14748.1 CCC68057.1 - 6.3e-33 112.9 0.1 1.1e-32 112.2 0.1 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 CCC68057.1 - 3.4e-10 40.2 0.2 1e-09 38.6 0.1 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CCC68057.1 - 0.0049 16.3 0.0 0.0088 15.4 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DapB_N PF01113.15 CCC68057.1 - 0.0053 16.6 0.2 0.024 14.5 0.1 2.2 1 1 1 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Ribosomal_S7 PF00177.16 CCC68058.1 - 2.9e-39 134.0 1.7 3.9e-39 133.5 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Carn_acyltransf PF00755.15 CCC68059.1 - 4.3e-79 266.1 0.2 2.5e-65 220.7 0.1 2.1 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Zn_clus PF00172.13 CCC68060.1 - 1.2e-08 34.7 11.3 2.3e-08 33.7 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GTP_EFTU PF00009.22 CCC68061.1 - 1.8e-38 131.8 0.0 3.2e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 CCC68061.1 - 1.7e-36 124.1 0.3 3.5e-36 123.1 0.2 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 CCC68061.1 - 2e-11 43.8 1.8 5.4e-11 42.4 0.3 2.5 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCC68061.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCC68061.1 - 0.23 11.2 1.7 0.93 9.2 0.0 2.6 3 1 1 4 4 4 0 Dynamin family Pkinase PF00069.20 CCC68062.1 - 3.6e-74 249.1 0.0 4.8e-74 248.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68062.1 - 1.3e-30 106.3 0.0 4.9e-29 101.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC68062.1 - 0.033 13.1 0.1 0.083 11.8 0.0 1.6 1 1 0 1 1 1 0 Kinase-like DUF3724 PF12521.3 CCC68062.1 - 0.052 13.2 1.2 0.26 11.0 0.8 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) Seadorna_VP7 PF07387.6 CCC68062.1 - 0.062 12.1 0.2 0.1 11.3 0.1 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 ORC4_C PF14629.1 CCC68063.1 - 8.1e-33 113.5 4.2 8.1e-33 113.5 2.9 1.8 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 4 C-terminus Arch_ATPase PF01637.13 CCC68063.1 - 1e-05 25.3 0.7 3.1e-05 23.7 0.5 1.9 1 0 0 1 1 1 1 Archaeal ATPase CCDC-167 PF15188.1 CCC68063.1 - 0.057 13.3 0.3 0.22 11.5 0.2 2.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 Ras PF00071.17 CCC68065.1 - 3.4e-54 182.6 0.0 4e-54 182.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC68065.1 - 5.8e-16 59.0 0.0 9.3e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC68065.1 - 1.4e-06 27.6 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCC68065.1 - 0.014 14.5 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region LEA_5 PF00477.12 CCC68065.1 - 0.049 13.9 0.7 0.094 13.0 0.5 1.5 1 0 0 1 1 1 0 Small hydrophilic plant seed protein SRPRB PF09439.5 CCC68065.1 - 0.074 12.2 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Ribosomal_S14 PF00253.16 CCC68066.1 - 1.6e-17 62.5 0.1 4.3e-17 61.2 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e PAPS_reduct PF01507.14 CCC68067.1 - 1.4e-41 142.2 0.0 2.2e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family WD40 PF00400.27 CCC68068.1 - 2.9e-05 23.7 0.4 0.1 12.5 0.0 4.9 6 0 0 6 6 6 1 WD domain, G-beta repeat PQQ_3 PF13570.1 CCC68068.1 - 0.00058 20.0 0.0 2.6 8.4 0.0 3.8 4 0 0 4 4 4 2 PQQ-like domain Pyridox_oxidase PF01243.15 CCC68070.1 - 5.6e-16 58.3 0.0 1.9e-15 56.6 0.0 1.9 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 CCC68070.1 - 0.002 17.9 0.0 0.68 9.7 0.0 2.1 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase AAA PF00004.24 CCC68071.1 - 3.2e-44 150.3 0.0 7.1e-44 149.2 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 CCC68071.1 - 9.1e-31 105.5 0.2 3.9e-30 103.5 0.2 2.0 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 CCC68071.1 - 4.4e-22 77.7 7.4 1.4e-21 76.0 3.9 2.6 3 0 0 3 3 2 1 MIT (microtubule interacting and transport) domain AAA_5 PF07728.9 CCC68071.1 - 4.6e-06 26.4 0.0 2.3e-05 24.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 CCC68071.1 - 5.6e-06 27.1 0.1 3.6e-05 24.5 0.0 2.4 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.7 CCC68071.1 - 1.2e-05 24.4 0.0 1.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCC68071.1 - 1.2e-05 25.4 1.0 0.0066 16.5 0.0 2.9 2 1 1 3 3 2 1 AAA domain IstB_IS21 PF01695.12 CCC68071.1 - 2e-05 24.0 0.0 5.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCC68071.1 - 3.5e-05 23.7 0.1 0.00014 21.7 0.0 2.0 3 0 0 3 3 1 1 AAA domain AAA_16 PF13191.1 CCC68071.1 - 4.7e-05 23.4 0.1 0.00017 21.6 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.8 CCC68071.1 - 4.8e-05 22.4 0.0 0.00074 18.5 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_2 PF07724.9 CCC68071.1 - 7.4e-05 22.7 0.1 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 CCC68071.1 - 9.8e-05 21.2 0.0 0.00018 20.3 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_25 PF13481.1 CCC68071.1 - 0.0001 21.8 0.1 0.019 14.3 0.0 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCC68071.1 - 0.00012 22.1 0.3 0.0092 16.1 0.0 3.0 3 0 0 3 3 3 1 RNA helicase AAA_33 PF13671.1 CCC68071.1 - 0.00052 19.8 0.0 0.0013 18.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCC68071.1 - 0.009 16.3 0.0 0.029 14.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CCC68071.1 - 0.016 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CCC68071.1 - 0.018 14.8 0.3 0.11 12.3 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCC68071.1 - 0.02 14.6 0.0 0.055 13.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Torsin PF06309.6 CCC68071.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Torsin Zeta_toxin PF06414.7 CCC68071.1 - 0.021 13.9 0.2 0.21 10.6 0.0 2.4 1 1 2 3 3 3 0 Zeta toxin Mg_chelatase PF01078.16 CCC68071.1 - 0.025 13.7 0.0 0.059 12.5 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 CCC68071.1 - 0.028 14.0 0.0 0.63 9.6 0.0 2.3 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.11 CCC68071.1 - 0.03 13.5 0.0 0.08 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Arch_ATPase PF01637.13 CCC68071.1 - 0.033 13.8 0.0 0.25 11.0 0.0 2.2 1 1 1 2 2 2 0 Archaeal ATPase KaiC PF06745.8 CCC68071.1 - 0.039 13.0 0.1 3.3 6.7 0.0 2.3 1 1 1 2 2 2 0 KaiC Sigma54_activat PF00158.21 CCC68071.1 - 0.061 12.7 0.0 0.21 11.0 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 CCC68071.1 - 0.074 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 CCC68071.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 CCC68071.1 - 0.11 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 CCC68071.1 - 0.15 11.7 0.1 0.35 10.4 0.0 1.7 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NBP1 PF08537.5 CCC68072.1 - 2.8e-20 72.7 11.2 4.3e-20 72.1 7.8 1.2 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 HalX PF08663.5 CCC68072.1 - 0.067 13.1 0.3 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 HalX domain CAML PF14963.1 CCC68072.1 - 0.15 11.3 3.5 0.24 10.7 2.4 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Vasculin PF15337.1 CCC68072.1 - 0.15 12.5 2.8 1.4 9.4 0.1 2.4 2 0 0 2 2 2 0 Vascular protein family Vasculin-like 1 Zip PF02535.17 CCC68072.1 - 0.85 8.5 2.6 0.94 8.4 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_E_B PF04042.11 CCC68073.1 - 1.4e-51 174.6 0.6 2.7e-51 173.8 0.4 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Na_trans_assoc PF06512.8 CCC68073.1 - 2.7 7.9 9.1 0.33 10.9 2.8 1.9 2 0 0 2 2 2 0 Sodium ion transport-associated Prenyltrans PF00432.16 CCC68074.1 - 3.2e-67 221.7 1.3 7.2e-14 51.0 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCC68074.1 - 6.9e-35 119.8 0.0 7e-14 52.2 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCC68074.1 - 6.4e-11 42.2 0.0 3.4e-05 23.8 0.0 3.1 1 1 1 2 2 2 2 Prenyltransferase-like A2M_comp PF07678.9 CCC68074.1 - 0.002 17.4 0.0 0.069 12.3 0.0 3.0 2 2 2 4 4 4 1 A-macroglobulin complement component WD40 PF00400.27 CCC68075.1 - 1.3e-54 180.1 18.9 1.5e-11 43.6 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CCC68075.1 - 1.6e-05 24.7 0.1 0.039 13.6 0.0 3.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A HDA2-3 PF11496.3 CCC68076.1 - 3.2e-85 285.5 0.7 3.2e-85 285.5 0.5 1.9 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 ThiF PF00899.16 CCC68077.1 - 2.2e-18 66.4 0.0 4.4e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 ThiF family Methyltransf_31 PF13847.1 CCC68077.1 - 0.027 14.0 0.1 0.05 13.1 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Sec23_trunk PF04811.10 CCC68078.1 - 3.7e-71 239.3 0.0 5.2e-71 238.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCC68078.1 - 2e-34 117.1 0.2 4.9e-34 115.8 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCC68078.1 - 3.4e-29 101.2 0.1 8.4e-29 99.9 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCC68078.1 - 6.8e-12 44.7 9.4 1.5e-11 43.6 6.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCC68078.1 - 1.6e-11 43.7 0.0 3.3e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat PIG-U PF06728.8 CCC68079.1 - 2.1e-102 342.8 43.3 2.5e-102 342.6 30.0 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U LSM PF01423.17 CCC68080.1 - 6.9e-15 54.3 0.2 7.9e-15 54.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain Glycos_transf_2 PF00535.21 CCC68081.1 - 3.9e-29 101.5 0.0 5.2e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 CCC68081.1 - 2.9e-08 33.1 0.0 4.2e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 CCC68081.1 - 7.4e-07 29.1 0.0 8.6e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 MRAP PF15183.1 CCC68081.1 - 0.87 9.2 4.5 1.4 8.5 3.1 1.3 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Med11 PF10280.4 CCC68082.1 - 1.2e-25 89.8 0.9 1.4e-25 89.6 0.6 1.1 1 0 0 1 1 1 1 Mediator complex protein hDGE_amylase PF14701.1 CCC68083.1 - 4.2e-173 576.0 1.3 5.9e-173 575.6 0.9 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 CCC68083.1 - 1.1e-123 412.7 0.0 1.7e-123 412.0 0.0 1.3 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 CCC68083.1 - 4.2e-72 242.4 0.0 7.2e-72 241.6 0.0 1.4 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 CCC68083.1 - 3.7e-21 74.7 0.0 1.3e-20 72.9 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 CCC68083.1 - 1.7e-09 37.5 1.1 1e-06 28.3 0.8 2.4 2 0 0 2 2 2 2 Alpha amylase, catalytic domain ATG13 PF10033.4 CCC68084.1 - 4e-61 206.4 0.3 6.7e-61 205.6 0.2 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 zf-C2H2 PF00096.21 CCC68085.1 - 9e-25 85.4 77.4 2.5e-05 24.3 2.4 9.6 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC68085.1 - 4e-21 73.7 74.0 2.8e-05 24.1 1.6 9.6 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCC68085.1 - 4.8e-15 55.0 77.2 0.00011 22.3 0.3 10.9 11 0 0 11 11 11 7 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCC68085.1 - 0.00015 21.7 12.6 0.0068 16.5 1.0 8.5 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCC68085.1 - 0.0011 19.1 6.8 0.018 15.2 0.2 8.7 10 0 0 10 10 10 3 Zinc-finger of C2H2 type CpXC PF14353.1 CCC68085.1 - 0.0026 17.7 1.7 0.0026 17.7 1.2 4.1 2 1 0 3 3 3 1 CpXC protein zf-C2HC_2 PF13913.1 CCC68085.1 - 0.022 14.4 0.9 0.022 14.4 0.7 5.8 6 0 0 6 6 6 0 zinc-finger of a C2HC-type zf-C2H2_2 PF12756.2 CCC68085.1 - 0.38 10.8 48.9 0.2 11.7 1.4 6.4 2 1 2 5 5 5 0 C2H2 type zinc-finger (2 copies) zf-FCS PF06467.9 CCC68085.1 - 1.9 8.1 25.3 3.3 7.4 4.9 5.2 4 1 1 5 5 5 0 MYM-type Zinc finger with FCS sequence motif DUF904 PF06005.7 CCC68085.1 - 5.1 7.4 10.9 4.2 7.7 5.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) RNA_pol_Rpb6 PF01192.17 CCC68086.1 - 2.3e-23 81.7 0.3 3.5e-23 81.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 EF-hand_7 PF13499.1 CCC68087.1 - 5e-11 42.5 2.1 3.3e-09 36.7 0.0 2.7 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 CCC68087.1 - 3.4e-09 35.8 3.4 2.9e-05 23.5 0.1 5.8 4 2 1 5 5 5 1 EF-hand domain EF-hand_5 PF13202.1 CCC68087.1 - 9.6e-08 31.0 2.6 2.9e-06 26.3 0.1 3.5 3 0 0 3 3 3 1 EF hand EF-hand_1 PF00036.27 CCC68087.1 - 8.3e-07 27.8 8.8 0.00011 21.2 0.1 4.8 6 0 0 6 6 6 1 EF hand Tenui_NCP PF04876.7 CCC68087.1 - 0.0002 20.9 0.3 0.00026 20.5 0.2 1.2 1 0 0 1 1 1 1 Tenuivirus major non-capsid protein SPARC_Ca_bdg PF10591.4 CCC68087.1 - 0.016 15.2 0.3 0.062 13.3 0.0 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF1456 PF07308.8 CCC68087.1 - 0.019 15.0 1.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1456) EF-hand_8 PF13833.1 CCC68087.1 - 0.023 14.3 2.8 0.075 12.6 0.2 3.1 3 1 0 3 3 3 0 EF-hand domain pair DUF892 PF05974.7 CCC68087.1 - 0.055 13.2 1.5 0.3 10.9 0.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF892) Prefoldin_3 PF13758.1 CCC68087.1 - 0.17 11.6 1.5 0.28 10.9 0.2 1.9 2 0 0 2 2 2 0 Prefoldin subunit TPR_11 PF13414.1 CCC68088.1 - 3.7e-39 132.2 13.0 4.7e-07 29.3 0.0 10.2 9 2 1 11 11 11 9 TPR repeat TPR_19 PF14559.1 CCC68088.1 - 6.7e-31 106.4 2.5 2.4e-07 30.9 0.0 10.5 9 3 2 11 11 10 6 Tetratricopeptide repeat TPR_2 PF07719.12 CCC68088.1 - 1.5e-26 90.1 3.2 0.00027 20.6 0.0 13.4 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCC68088.1 - 4.3e-26 90.9 0.0 6.4e-06 26.6 0.0 8.9 9 2 2 11 11 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCC68088.1 - 1.9e-24 83.9 0.0 0.1 13.3 0.0 12.9 11 4 6 17 17 13 5 Tetratricopeptide repeat TPR_17 PF13431.1 CCC68088.1 - 2.5e-22 77.1 8.0 0.0045 17.0 0.0 11.2 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_1 PF00515.23 CCC68088.1 - 7.6e-19 66.4 15.5 5.1e-05 22.7 0.0 12.7 15 0 0 15 15 14 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCC68088.1 - 4.4e-16 58.5 15.9 6.4e-05 22.8 0.0 9.2 8 2 3 11 11 11 6 Tetratricopeptide repeat TPR_6 PF13174.1 CCC68088.1 - 2e-14 52.9 4.0 0.055 13.9 0.0 10.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 CCC68088.1 - 3e-12 45.3 21.3 0.00082 18.9 0.0 10.3 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_7 PF13176.1 CCC68088.1 - 4.2e-11 41.7 3.5 0.31 10.9 0.0 9.1 12 0 0 12 12 9 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCC68088.1 - 2.4e-08 33.6 0.1 1.9 8.4 0.0 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 CCC68088.1 - 3.9e-06 26.8 0.1 2.8 8.1 0.0 5.7 4 1 1 5 5 5 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.5 CCC68088.1 - 0.00071 19.1 0.0 0.0042 16.5 0.0 2.4 1 1 1 2 2 2 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.1 CCC68088.1 - 0.0012 18.7 0.2 5.1 7.1 0.0 5.5 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_5 PF12688.2 CCC68088.1 - 0.01 15.8 0.0 0.9 9.5 0.0 2.9 2 0 0 2 2 2 0 Tetratrico peptide repeat Alkyl_sulf_dimr PF14863.1 CCC68088.1 - 0.048 13.8 1.0 6.3 7.0 0.1 3.8 4 1 1 5 5 4 0 Alkyl sulfatase dimerisation RNA_pol_Rpc82 PF05645.8 CCC68089.1 - 3.2e-68 230.0 3.1 1.3e-67 228.0 1.2 2.1 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 CCC68089.1 - 7.8e-22 76.9 3.9 3e-17 62.2 0.2 3.7 4 0 0 4 4 4 2 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 CCC68089.1 - 4.7e-07 29.2 2.1 0.0075 15.7 0.2 3.0 3 0 0 3 3 3 2 TFIIE alpha subunit Peptidase_M16 PF00675.15 CCC68090.1 - 5.2e-23 81.4 0.0 9.8e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCC68090.1 - 0.00014 21.6 0.3 0.00074 19.2 0.0 2.3 2 1 0 2 2 2 1 Peptidase M16 inactive domain PALP PF00291.20 CCC68091.1 - 1.9e-60 204.6 0.0 2.2e-60 204.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Sir1 PF11603.3 CCC68092.1 - 4.8e-11 42.9 0.1 8.2e-09 35.6 0.0 2.7 2 0 0 2 2 2 2 Regulatory protein Sir1 Homeobox PF00046.24 CCC68093.1 - 6.1e-12 44.9 1.4 9.9e-12 44.2 1.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCC68093.1 - 8.1e-05 22.2 0.4 0.00014 21.4 0.3 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 CCC68093.1 - 0.0068 15.4 0.0 0.0099 14.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HTH_28 PF13518.1 CCC68093.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain Sir1 PF11603.3 CCC68094.1 - 0.0018 18.3 0.1 0.66 10.1 0.0 2.9 2 1 0 2 2 2 2 Regulatory protein Sir1 GFO_IDH_MocA PF01408.17 CCC68095.1 - 7.4e-22 78.1 0.3 2.2e-21 76.5 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCC68095.1 - 3.6e-08 33.1 0.0 7.5e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain TFIID-18kDa PF02269.11 CCC68096.1 - 4.8e-33 112.8 0.0 7.6e-33 112.1 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Histone PF00125.19 CCC68096.1 - 0.0018 18.3 0.0 0.0067 16.5 0.0 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 CCC68096.1 - 0.0029 17.5 0.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) CENP-B_dimeris PF09026.5 CCC68096.1 - 0.022 14.9 5.2 0.034 14.3 3.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CBFD_NFYB_HMF PF00808.18 CCC68096.1 - 0.09 12.8 0.1 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pox_Ag35 PF03286.9 CCC68096.1 - 0.24 10.8 12.7 0.34 10.4 8.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4611 PF15387.1 CCC68096.1 - 0.35 11.0 9.5 0.57 10.3 6.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) ERO1 PF04137.10 CCC68097.1 - 6.8e-116 387.1 0.7 6.8e-116 387.1 0.5 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Muted PF14942.1 CCC68097.1 - 0.032 14.1 5.0 0.065 13.1 3.5 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Evr1_Alr PF04777.8 CCC68097.1 - 0.064 13.1 3.0 0.44 10.4 0.4 2.8 2 0 0 2 2 2 0 Erv1 / Alr family DUF1765 PF08578.5 CCC68097.1 - 4.6 7.3 9.9 5.2 7.1 1.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1765) Utp14 PF04615.8 CCC68098.1 - 1.9e-203 677.6 72.0 1.9e-203 677.6 49.9 2.1 1 1 1 2 2 2 1 Utp14 protein Proteasome PF00227.21 CCC68099.1 - 8.1e-58 194.8 0.0 1e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCC68099.1 - 3.8e-09 35.6 0.8 7e-09 34.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Rtf2 PF04641.7 CCC68100.1 - 9.2e-41 139.7 2.0 1e-40 139.5 1.4 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.1 CCC68100.1 - 0.00027 20.4 0.0 0.00059 19.3 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Rad50_zn_hook PF04423.9 CCC68100.1 - 0.0035 16.7 0.1 0.0035 16.7 0.1 2.7 3 0 0 3 3 3 1 Rad50 zinc hook motif Ish1 PF10281.4 CCC68102.1 - 1.2e-44 150.0 37.2 2.1e-12 46.8 0.1 6.7 6 0 0 6 6 6 5 Putative stress-responsive nuclear envelope protein SAP PF02037.22 CCC68102.1 - 9.9e-05 21.7 0.0 1.2 8.7 0.0 4.3 5 0 0 5 5 5 2 SAP domain Phasin PF05597.6 CCC68102.1 - 0.0046 16.7 10.8 0.027 14.2 0.1 4.6 5 0 0 5 5 5 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Uteroglobin PF01099.12 CCC68102.1 - 0.012 15.4 1.6 15 5.5 0.0 4.1 3 0 0 3 3 3 0 Uteroglobin family SAP30_Sin3_bdg PF13867.1 CCC68102.1 - 0.029 14.2 7.2 3.7 7.4 0.0 4.3 4 1 0 4 4 4 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Pro-kuma_activ PF09286.6 CCC68102.1 - 0.034 14.1 0.5 1.9 8.5 0.0 3.4 4 0 0 4 4 4 0 Pro-kumamolisin, activation domain HeH PF12949.2 CCC68102.1 - 0.32 10.5 4.5 4.9 6.7 0.1 3.8 4 1 0 4 4 4 0 HeH/LEM domain SAM_2 PF07647.12 CCC68102.1 - 1.6 8.6 7.6 19 5.1 0.1 5.1 5 1 1 6 6 6 0 SAM domain (Sterile alpha motif) YtxH PF12732.2 CCC68102.1 - 2.3 8.6 23.7 1.3e+02 3.0 3.5 5.9 3 2 0 3 3 3 0 YtxH-like protein Carbpep_Y_N PF05388.6 CCC68102.1 - 5.5 7.1 14.9 1.3 9.1 0.1 4.7 4 1 0 4 4 4 0 Carboxypeptidase Y pro-peptide FAD_binding_6 PF00970.19 CCC68104.1 - 2.9e-26 91.4 0.0 4.6e-26 90.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CCC68104.1 - 1.7e-24 86.4 0.0 2.6e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CCC68104.1 - 3.1e-05 23.9 0.0 0.0011 18.9 0.0 2.2 1 1 1 2 2 2 1 Ferric reductase NAD binding domain DUF4131 PF13567.1 CCC68104.1 - 0.11 11.9 0.0 0.36 10.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Tubulin_C PF03953.12 CCC68105.1 - 4.3e-48 162.5 0.1 6.6e-48 161.9 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin PF00091.20 CCC68105.1 - 4.5e-32 111.6 0.0 6.8e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain MSP PF01716.13 CCC68105.1 - 0.11 11.5 0.1 0.24 10.4 0.0 1.6 2 0 0 2 2 2 0 Manganese-stabilising protein / photosystem II polypeptide Sugar_tr PF00083.19 CCC68106.1 - 1.2e-43 149.3 21.4 1.5e-43 149.0 14.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC68106.1 - 2.1e-23 82.6 15.9 3.5e-14 52.3 8.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Gtr1_RagA PF04670.7 CCC68107.1 - 4.6e-93 310.6 2.3 5.3e-93 310.4 1.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 CCC68107.1 - 4.8e-09 35.8 0.5 1.5e-08 34.2 0.1 1.8 2 0 0 2 2 2 1 Ras family Miro PF08477.8 CCC68107.1 - 1.2e-07 32.2 0.1 2.8e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC68107.1 - 1.4e-07 30.9 0.1 2.9e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCC68107.1 - 4e-06 26.7 0.0 8.6e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CCC68107.1 - 0.0038 17.5 0.3 0.009 16.3 0.1 1.9 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 CCC68107.1 - 0.01 15.3 0.2 0.022 14.3 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF815 PF05673.8 CCC68107.1 - 0.03 13.2 0.0 0.064 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AIG1 PF04548.11 CCC68107.1 - 0.034 13.2 0.4 0.23 10.5 0.1 2.2 1 1 1 2 2 2 0 AIG1 family Guanylate_kin PF00625.16 CCC68107.1 - 0.18 11.2 2.1 0.89 8.9 0.4 2.6 2 1 0 2 2 2 0 Guanylate kinase Pyr_redox_2 PF07992.9 CCC68108.1 - 3.8e-28 98.7 3.6 2.4e-18 66.7 0.0 3.7 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCC68108.1 - 1.6e-13 50.8 0.1 3.8e-11 43.2 0.1 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCC68108.1 - 4.7e-10 39.8 0.2 0.00025 21.1 0.0 3.2 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCC68108.1 - 0.0093 14.9 0.3 3.6 6.4 0.1 3.2 2 1 2 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Auxin_repressed PF05564.7 CCC68108.1 - 0.24 12.0 3.5 1.6 9.3 1.3 2.5 2 0 0 2 2 2 0 Dormancy/auxin associated protein DUF2989 PF11207.3 CCC68109.1 - 0.064 12.6 4.8 0.11 11.9 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) Ribosomal_L30 PF00327.15 CCC68110.1 - 3.9e-12 45.5 0.3 7.9e-12 44.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Exo_endo_phos PF03372.18 CCC68111.1 - 7.5e-20 71.9 0.0 1.6e-19 70.8 0.0 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Nab6_mRNP_bdg PF10567.4 CCC68112.1 - 1.9e-88 296.4 16.3 1.9e-88 296.4 11.3 2.3 3 0 0 3 3 3 1 RNA-recognition motif RRM PF10378.4 CCC68112.1 - 3e-17 61.9 7.0 3e-17 61.9 4.9 3.1 2 1 1 3 3 3 1 Putative RRM domain RRM_6 PF14259.1 CCC68112.1 - 1.6e-08 34.3 0.4 2.3e-05 24.2 0.1 3.3 4 0 0 4 4 4 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC68112.1 - 9e-06 25.4 0.8 0.0022 17.7 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCC68112.1 - 0.0049 16.4 0.1 0.32 10.6 0.0 3.5 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 CCC68113.1 - 9.1e-35 120.0 60.2 5.8e-33 114.0 39.5 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCC68113.1 - 1.3e-05 23.9 8.2 1.3e-05 23.9 5.7 2.6 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 CCC68113.1 - 0.56 8.5 48.1 0.92 7.8 1.4 3.7 1 1 1 3 3 3 0 MFS/sugar transport protein Anp1 PF03452.9 CCC68114.1 - 1.4e-125 417.8 0.0 2.3e-125 417.1 0.0 1.3 1 0 0 1 1 1 1 Anp1 BcsB PF03170.8 CCC68114.1 - 0.057 11.4 0.0 0.097 10.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit TAF8_C PF10406.4 CCC68115.1 - 7.9e-21 73.8 0.1 7.9e-21 73.8 0.1 2.0 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term SRP1_TIP1 PF00660.12 CCC68116.1 - 0.0038 17.0 2.3 0.0038 17.0 1.6 2.1 2 0 0 2 2 2 1 Seripauperin and TIP1 family CTK3_C PF12350.3 CCC68118.1 - 1.5e-18 66.5 5.6 4.4e-18 65.0 3.9 1.8 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus CTK3 PF12243.3 CCC68118.1 - 1.3e-09 37.7 5.7 2.2e-05 24.1 0.3 3.0 2 1 1 3 3 3 2 CTD kinase subunit gamma CTK3 Ribosomal_L20 PF00453.13 CCC68118.1 - 0.91 9.4 0.0 0.91 9.4 0.0 2.9 2 1 0 2 2 2 0 Ribosomal protein L20 SRP1_TIP1 PF00660.12 CCC68119.1 - 4.5e-19 68.2 0.2 1.3e-18 66.7 0.1 1.9 1 0 0 1 1 1 1 Seripauperin and TIP1 family ATP_bind_1 PF03029.12 CCC68121.1 - 1.5e-80 270.1 0.1 2e-80 269.7 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 CCC68121.1 - 3.4e-05 24.6 0.6 0.0013 19.5 0.0 2.9 3 1 0 3 3 3 1 AAA domain AAA_10 PF12846.2 CCC68121.1 - 0.00013 21.5 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 CCC68121.1 - 0.0014 18.5 0.0 0.0061 16.5 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 CCC68121.1 - 0.0018 18.5 3.1 0.7 10.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CCC68121.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 CCC68121.1 - 0.032 14.0 0.1 0.083 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 CCC68121.1 - 0.046 12.5 0.3 0.14 10.9 0.0 1.8 2 0 0 2 2 2 0 ArgK protein RNA_helicase PF00910.17 CCC68121.1 - 0.093 12.9 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 CCC68121.1 - 0.16 11.5 0.0 0.42 10.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain zf-CCHC_4 PF14392.1 CCC68123.1 - 3.9e-05 23.2 13.4 0.36 10.5 0.2 3.5 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.1 CCC68123.1 - 0.044 13.4 0.2 0.044 13.4 0.2 2.9 3 0 0 3 3 3 0 Zinc knuckle TBCA PF02970.11 CCC68124.1 - 7.8e-28 96.3 9.8 9.5e-28 96.1 6.8 1.0 1 0 0 1 1 1 1 Tubulin binding cofactor A Hanta_nucleocap PF00846.13 CCC68124.1 - 0.012 14.3 1.5 0.013 14.2 1.0 1.0 1 0 0 1 1 1 0 Hantavirus nucleocapsid protein TerB PF05099.8 CCC68124.1 - 0.013 15.2 0.5 0.016 14.9 0.4 1.1 1 0 0 1 1 1 0 Tellurite resistance protein TerB MSP1_C PF07462.6 CCC68124.1 - 0.017 13.5 4.2 0.019 13.3 2.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Mnd1 PF03962.10 CCC68124.1 - 0.1 12.2 4.4 0.12 12.0 3.1 1.1 1 0 0 1 1 1 0 Mnd1 family Fzo_mitofusin PF04799.8 CCC68124.1 - 0.11 11.8 1.4 0.13 11.5 1.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region Atg14 PF10186.4 CCC68124.1 - 0.12 11.3 2.1 0.14 11.0 1.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 CCC68124.1 - 0.14 10.5 4.7 0.16 10.3 3.3 1.0 1 0 0 1 1 1 0 AAA domain rve_2 PF13333.1 CCC68124.1 - 0.15 12.1 2.4 1.5 8.9 0.1 2.3 2 0 0 2 2 2 0 Integrase core domain Orthopox_A5L PF06193.6 CCC68124.1 - 0.22 11.4 3.1 0.25 11.2 1.8 1.2 1 1 0 1 1 1 0 Orthopoxvirus A5L protein-like UPF0240 PF06784.6 CCC68124.1 - 0.23 11.1 3.0 0.27 10.9 2.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0240) DUF342 PF03961.8 CCC68124.1 - 0.28 9.5 4.9 0.3 9.4 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3166 PF11365.3 CCC68124.1 - 0.33 11.4 3.8 2.2 8.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) IncA PF04156.9 CCC68124.1 - 2 7.9 7.9 2.3 7.7 5.5 1.1 1 0 0 1 1 1 0 IncA protein Pkinase PF00069.20 CCC68126.1 - 1.7e-57 194.5 0.5 8.6e-54 182.4 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68126.1 - 2.6e-18 66.0 0.0 1.4e-17 63.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase DUF605 PF04652.11 CCC68126.1 - 0.0036 16.7 50.0 0.034 13.5 13.5 2.1 2 0 0 2 2 2 2 Vta1 like APH PF01636.18 CCC68126.1 - 0.023 14.4 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CCC68126.1 - 0.029 13.3 0.0 0.066 12.1 0.0 1.6 1 1 0 1 1 1 0 Kinase-like WD40 PF00400.27 CCC68127.1 - 1.9e-39 132.1 3.9 1.9e-08 33.8 0.3 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat PQQ_3 PF13570.1 CCC68127.1 - 0.0036 17.5 0.0 0.37 11.1 0.0 3.2 3 0 0 3 3 3 1 PQQ-like domain Nup160 PF11715.3 CCC68127.1 - 0.0054 14.9 0.2 0.091 10.8 0.0 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 CCC68127.1 - 0.065 12.7 0.1 1 8.8 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain V_ATPase_I PF01496.14 CCC68128.1 - 1.9e-294 978.4 12.3 2.1e-294 978.2 8.5 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3487 PF11990.3 CCC68128.1 - 7.4 5.9 9.5 2.2 7.6 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Mtc PF03820.12 CCC68129.1 - 4.8e-125 416.2 0.1 5.4e-125 416.1 0.0 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF2371 PF10177.4 CCC68129.1 - 0.03 14.1 0.0 0.076 12.8 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2371) Polysacc_synt_C PF14667.1 CCC68129.1 - 7.5 6.3 10.3 0.18 11.5 1.9 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain SRP1_TIP1 PF00660.12 CCC68130.1 - 6.8e-26 90.1 0.2 1.6e-25 88.8 0.1 1.7 1 0 0 1 1 1 1 Seripauperin and TIP1 family Phycoerythr_ab PF02972.9 CCC68130.1 - 0.15 11.7 2.6 0.8 9.3 0.3 2.7 2 1 0 2 2 2 0 Phycoerythrin, alpha/beta chain SRP1_TIP1 PF00660.12 CCC68131.1 - 9.3e-28 96.1 0.3 1.3e-27 95.6 0.2 1.2 1 0 0 1 1 1 1 Seripauperin and TIP1 family Lsm_interact PF05391.6 CCC68131.1 - 0.21 11.0 0.6 0.52 9.8 0.1 2.0 2 0 0 2 2 2 0 Lsm interaction motif WD40 PF00400.27 CCC68132.1 - 2.3e-38 128.7 11.2 2.3e-08 33.6 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat NLE PF08154.7 CCC68132.1 - 6.6e-27 93.3 0.4 1.4e-26 92.2 0.3 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CCC68132.1 - 6e-10 37.8 6.8 0.0014 16.8 0.3 3.7 2 2 0 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCC68132.1 - 0.00098 17.9 9.2 0.041 12.6 0.3 3.8 1 1 2 4 4 4 2 Nup133 N terminal like MFS_1 PF07690.11 CCC68133.1 - 1.1e-24 86.7 31.5 1.1e-24 86.7 21.8 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily IPPT PF01715.12 CCC68134.1 - 4.8e-85 284.6 0.2 4.8e-85 284.6 0.1 1.6 2 0 0 2 2 2 1 IPP transferase AAA_17 PF13207.1 CCC68134.1 - 8.7e-06 26.5 0.6 4.4e-05 24.2 0.1 2.6 1 1 1 2 2 2 1 AAA domain IPT PF01745.11 CCC68134.1 - 4.3e-05 22.8 0.1 0.00041 19.6 0.0 2.5 3 1 0 3 3 3 1 Isopentenyl transferase AAA_22 PF13401.1 CCC68134.1 - 0.00035 20.7 0.3 0.22 11.6 0.0 3.2 2 2 1 3 3 3 1 AAA domain Zeta_toxin PF06414.7 CCC68134.1 - 0.00049 19.2 0.0 0.0015 17.6 0.0 1.9 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CCC68134.1 - 0.00071 19.8 1.7 0.0033 17.7 0.2 2.8 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCC68134.1 - 0.0065 16.3 0.3 0.022 14.6 0.0 2.2 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCC68134.1 - 0.0072 15.5 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 RNA_helicase PF00910.17 CCC68134.1 - 0.023 14.8 0.0 0.31 11.2 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.1 CCC68134.1 - 0.036 13.4 0.0 0.087 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain PPV_E1_C PF00519.12 CCC68134.1 - 0.038 12.6 0.9 0.051 12.1 0.1 1.5 2 0 0 2 2 2 0 Papillomavirus helicase IstB_IS21 PF01695.12 CCC68134.1 - 0.052 12.9 0.1 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Hpr_kinase_C PF07475.7 CCC68134.1 - 0.078 12.2 0.0 0.61 9.3 0.0 2.2 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain T2SE PF00437.15 CCC68134.1 - 0.13 11.1 0.4 0.23 10.3 0.3 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.18 CCC68134.1 - 0.3 10.4 1.2 0.67 9.3 0.7 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ABC_tran PF00005.22 CCC68134.1 - 1.8 8.8 4.9 1.6 9.0 1.6 2.4 2 1 0 2 2 2 0 ABC transporter BRO1 PF03097.13 CCC68135.1 - 5.7e-68 229.3 12.5 5.7e-68 229.3 8.7 1.8 3 0 0 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CCC68135.1 - 1.1e-25 90.2 15.0 1.1e-25 90.2 10.4 3.1 2 2 0 2 2 2 1 ALIX V-shaped domain binding to HIV RRP7 PF12923.2 CCC68136.1 - 0.25 11.3 1.4 0.66 9.9 0.9 1.8 1 1 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) DnaJ PF00226.26 CCC68137.1 - 1e-27 95.6 0.9 2e-27 94.7 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 CCC68137.1 - 2.5e-14 53.0 16.8 4.1e-14 52.3 11.6 1.3 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 CCC68137.1 - 8.1e-12 44.8 0.1 2e-10 40.4 0.0 2.8 3 0 0 3 3 3 1 DnaJ C terminal domain HypA PF01155.14 CCC68137.1 - 0.028 14.1 7.7 1.1 8.9 0.2 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrome_CBB3 PF13442.1 CCC68137.1 - 0.092 12.9 0.6 0.092 12.9 0.4 3.7 2 1 2 4 4 4 0 Cytochrome C oxidase, cbb3-type, subunit III Cytochrome_C7 PF14522.1 CCC68137.1 - 4.8 6.8 12.2 1.3 8.7 0.5 2.4 1 1 1 2 2 2 0 Cytochrome c7 Cytochrom_CIII PF02085.11 CCC68137.1 - 7.7 6.6 8.6 45 4.1 5.7 2.1 1 1 0 1 1 1 0 Class III cytochrome C family GATase PF00117.23 CCC68138.1 - 8.6e-42 142.7 0.0 1.5e-41 141.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 CCC68138.1 - 3.7e-41 138.7 0.1 8.3e-41 137.6 0.0 1.6 1 0 0 1 1 1 1 GMP synthase C terminal domain NAD_synthase PF02540.12 CCC68138.1 - 1.5e-08 33.8 0.0 3.2e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 CCC68138.1 - 3.7e-07 29.8 0.1 1.9e-06 27.4 0.0 2.4 2 1 0 2 2 2 1 Peptidase C26 PAPS_reduct PF01507.14 CCC68138.1 - 0.0061 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family QueC PF06508.8 CCC68138.1 - 0.016 14.5 0.0 0.32 10.2 0.0 2.2 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ThiI PF02568.9 CCC68138.1 - 0.018 14.4 0.0 0.041 13.3 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 CCC68138.1 - 0.019 13.5 0.1 0.04 12.4 0.0 1.5 1 0 0 1 1 1 0 tRNA methyl transferase Arginosuc_synth PF00764.14 CCC68138.1 - 0.027 13.5 0.1 0.042 12.8 0.1 1.2 1 0 0 1 1 1 0 Arginosuccinate synthase Asn_synthase PF00733.16 CCC68138.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase ATP_bind_3 PF01171.15 CCC68138.1 - 0.14 11.6 0.1 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 PP-loop family HEM4 PF02602.10 CCC68139.1 - 8.9e-40 136.3 0.0 1e-39 136.1 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD FSH1 PF03959.8 CCC68141.1 - 2e-67 226.7 0.0 2.7e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CCC68141.1 - 1e-07 31.7 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCC68141.1 - 3.9e-06 26.4 0.4 1.7e-05 24.4 0.1 2.1 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 CCC68141.1 - 0.0035 16.8 0.0 0.0089 15.4 0.0 1.7 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 CCC68141.1 - 0.0094 15.5 0.1 0.49 9.9 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCC68141.1 - 0.016 15.0 0.0 0.53 10.1 0.0 2.3 1 1 1 2 2 2 0 Alpha/beta hydrolase family WASH-7_N PF14745.1 CCC68141.1 - 0.052 11.7 0.0 0.079 11.1 0.0 1.2 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal UCH PF00443.24 CCC68142.1 - 3.2e-63 213.3 9.5 3.2e-63 213.3 6.6 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC68142.1 - 5.9e-23 81.7 9.8 5.9e-23 81.7 6.8 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCC68142.1 - 3.5e-11 43.0 6.2 3.5e-11 43.0 4.3 3.4 4 1 0 4 4 4 1 Zn-finger in ubiquitin-hydrolases and other protein UPF0047 PF01894.12 CCC68142.1 - 0.035 13.9 0.0 0.093 12.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0047 Phosducin PF02114.11 CCC68143.1 - 4.5e-09 35.4 1.8 0.00099 17.9 0.0 2.1 2 0 0 2 2 2 2 Phosducin His_Phos_1 PF00300.17 CCC68144.1 - 4.4e-29 101.6 0.0 5.4e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Rhodanese PF00581.15 CCC68145.1 - 1.4e-19 70.5 0.0 1.6e-19 70.2 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Rhodanese PF00581.15 CCC68146.1 - 3.3e-12 46.7 0.0 4.5e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF947 PF06102.7 CCC68147.1 - 7.4e-45 152.7 30.7 7.4e-45 152.7 21.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF947) Thioredoxin PF00085.15 CCC68148.1 - 1.5e-24 85.6 0.1 5.9e-24 83.7 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.1 CCC68148.1 - 1.3e-08 34.9 0.2 0.0003 20.6 0.0 2.9 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CCC68148.1 - 1.4e-06 28.4 0.3 6.1e-06 26.4 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCC68148.1 - 7.3e-06 26.0 0.1 0.00017 21.6 0.0 2.9 2 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 CCC68148.1 - 0.00039 20.3 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 CCC68148.1 - 0.024 14.4 0.0 0.048 13.4 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Glutaredoxin PF00462.19 CCC68148.1 - 0.052 13.5 0.1 0.17 11.9 0.1 1.9 1 0 0 1 1 1 0 Glutaredoxin AMMECR1 PF01871.12 CCC68149.1 - 1.2e-32 112.3 0.0 1.6e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 P5-ATPase PF12409.3 CCC68151.1 - 3.7e-36 123.5 0.1 1.8e-35 121.3 0.0 2.3 2 0 0 2 2 2 1 P5-type ATPase cation transporter E1-E2_ATPase PF00122.15 CCC68151.1 - 5.6e-28 97.5 0.0 1.2e-27 96.4 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CCC68151.1 - 2.9e-26 92.8 0.0 6.1e-26 91.7 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC68151.1 - 2.2e-18 67.4 0.0 2.6e-17 63.9 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCC68151.1 - 2.1e-06 27.5 0.0 5.3e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCC68151.1 - 0.00029 20.4 0.2 0.45 10.0 0.0 3.3 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Mpv17_PMP22 PF04117.7 CCC68152.1 - 6.7e-21 73.7 1.2 6.7e-21 73.7 0.8 2.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family S10_plectin PF03501.10 CCC68153.1 - 4.1e-42 141.9 1.1 4.8e-42 141.7 0.8 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF505 PF04458.7 CCC68153.1 - 0.005 15.0 0.5 0.0059 14.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF505) YjcQ PF09639.5 CCC68153.1 - 0.015 15.3 0.4 0.023 14.7 0.3 1.3 1 0 0 1 1 1 0 YjcQ protein PadR PF03551.9 CCC68153.1 - 0.016 14.9 0.4 0.016 14.9 0.3 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family DUF1975 PF09318.5 CCC68153.1 - 0.019 14.5 3.5 0.023 14.3 2.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1975) HTH_45 PF14947.1 CCC68153.1 - 0.026 14.3 0.3 0.049 13.4 0.2 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix RRS1 PF04939.7 CCC68154.1 - 6.5e-65 217.5 3.4 7.5e-65 217.3 2.3 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) SWIB PF02201.13 CCC68155.1 - 2.6e-15 55.8 0.0 4.6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 SWIB/MDM2 domain DUF3450 PF11932.3 CCC68155.1 - 0.082 12.1 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) C2 PF00168.25 CCC68156.1 - 1.8e-09 37.3 0.0 4.7e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.4 CCC68156.1 - 6.4e-08 32.4 0.6 4e-07 29.8 0.0 2.7 3 1 0 3 3 3 1 Munc13 (mammalian uncoordinated) homology domain Oxidored_FMN PF00724.15 CCC68157.1 - 2.5e-125 417.9 0.0 2.9e-125 417.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Cauli_VI PF01693.11 CCC68158.1 - 1.7e-27 95.1 4.0 8.9e-20 70.4 1.1 2.5 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 CCC68158.1 - 1.2e-25 90.3 0.1 3.7e-25 88.7 0.0 1.8 2 0 0 2 2 2 1 RNase H CybS PF05328.7 CCC68159.1 - 1.6e-39 134.5 0.0 2.1e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 CybS Acyltransferase PF01553.16 CCC68160.1 - 0.00016 21.1 0.3 0.013 14.8 0.1 2.7 1 1 1 2 2 2 2 Acyltransferase Ssl1 PF04056.9 CCC68160.1 - 0.0099 15.4 0.7 0.022 14.3 0.5 1.5 1 0 0 1 1 1 1 Ssl1-like YbaJ PF10757.4 CCC68160.1 - 1.2 9.2 6.3 2 8.5 0.0 3.5 2 2 1 3 3 3 0 Biofilm formation regulator YbaJ ChAPs PF09295.5 CCC68161.1 - 9e-167 554.7 2.6 1.1e-166 554.4 1.8 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 CCC68161.1 - 3.2e-05 23.5 2.5 0.42 10.3 0.2 3.3 3 0 0 3 3 3 2 TPR repeat TPR_8 PF13181.1 CCC68161.1 - 0.00014 21.3 0.1 2.1 8.3 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCC68161.1 - 0.0047 17.4 0.4 26 5.8 0.0 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCC68161.1 - 0.0092 15.8 4.7 0.05 13.5 0.1 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCC68161.1 - 0.01 16.4 0.1 3.6 8.3 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 CCC68161.1 - 0.021 15.1 0.5 7.8 6.9 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CCC68161.1 - 0.038 14.1 6.6 2.2 8.4 0.1 3.8 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCC68161.1 - 0.065 13.7 0.5 45 4.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCC68161.1 - 0.12 12.0 0.3 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RGS PF00615.14 CCC68162.1 - 0.00035 20.6 1.1 0.0026 17.8 0.2 2.3 2 0 0 2 2 2 1 Regulator of G protein signaling domain DUF2628 PF10947.3 CCC68162.1 - 0.55 10.0 4.4 0.95 9.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2628) Leader_CPA1 PF08252.6 CCC68163.1 - 1.7e-15 55.8 3.0 1.8e-15 55.7 2.1 1.0 1 0 0 1 1 1 1 arg-2/CPA1 leader peptide GATase PF00117.23 CCC68164.1 - 1.2e-46 158.6 0.0 1.6e-46 158.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 CCC68164.1 - 6.3e-45 151.8 0.0 9.4e-45 151.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 CCC68164.1 - 3.5e-05 23.3 0.1 0.00091 18.7 0.1 2.5 2 1 0 2 2 2 1 Peptidase C26 SNF2_N PF00176.18 CCC68165.1 - 3.2e-82 275.6 1.0 7.1e-82 274.5 0.7 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CCC68165.1 - 6.2e-44 148.5 4.0 6.2e-44 148.5 2.8 3.8 5 0 0 5 5 5 1 SLIDE HAND PF09110.6 CCC68165.1 - 4.5e-33 114.0 18.5 4.5e-33 114.0 12.8 4.3 3 1 0 3 3 3 1 HAND Helicase_C PF00271.26 CCC68165.1 - 3.3e-16 58.9 0.0 1.8e-15 56.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCC68165.1 - 4.4e-07 29.5 0.0 1.1e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCC68165.1 - 0.048 13.8 1.8 0.22 11.6 0.0 3.1 4 0 0 4 4 4 0 AAA domain Laminin_II PF06009.7 CCC68166.1 - 0.00029 20.6 3.4 0.00036 20.3 2.4 1.0 1 0 0 1 1 1 1 Laminin Domain II SF-assemblin PF06705.6 CCC68166.1 - 0.014 14.5 2.3 0.014 14.5 1.6 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin Dor1 PF04124.7 CCC68166.1 - 0.029 12.8 0.7 0.03 12.8 0.5 1.0 1 0 0 1 1 1 0 Dor1-like family RmuC PF02646.11 CCC68166.1 - 0.045 12.5 0.8 0.048 12.4 0.6 1.0 1 0 0 1 1 1 0 RmuC family Transposase_22 PF02994.9 CCC68166.1 - 0.064 11.7 2.2 0.066 11.7 1.5 1.1 1 0 0 1 1 1 0 L1 transposable element Baculo_PEP_C PF04513.7 CCC68166.1 - 0.077 12.8 1.1 0.099 12.4 0.8 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus NYD-SP28 PF14772.1 CCC68166.1 - 0.12 12.4 2.0 0.24 11.4 1.4 1.6 1 1 0 1 1 1 0 Sperm tail Streptin-Immun PF11083.3 CCC68166.1 - 0.14 12.1 4.2 0.94 9.5 0.6 2.0 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein DUF4618 PF15397.1 CCC68166.1 - 0.14 11.4 2.8 0.15 11.3 2.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4559 PF15112.1 CCC68166.1 - 0.42 9.7 2.8 0.42 9.7 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Sipho_Gp157 PF05565.6 CCC68166.1 - 0.45 10.0 4.8 0.46 10.0 3.3 1.0 1 0 0 1 1 1 0 Siphovirus Gp157 Syntaxin PF00804.20 CCC68166.1 - 0.64 10.2 4.4 1.2 9.3 3.0 1.6 1 1 0 1 1 1 0 Syntaxin XhlA PF10779.4 CCC68166.1 - 0.68 9.8 4.2 3.1 7.7 2.9 2.0 1 1 0 1 1 1 0 Haemolysin XhlA DUF2034 PF10356.4 CCC68167.1 - 8.7e-53 178.2 0.0 1.1e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 CCC68167.1 - 0.0015 18.3 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 2 Restriction endonuclease Pollen_Ole_e_I PF01190.12 CCC68167.1 - 0.16 11.8 0.0 0.52 10.1 0.0 1.7 2 0 0 2 2 2 0 Pollen proteins Ole e I like MFS_1 PF07690.11 CCC68168.1 - 1.1e-28 100.0 47.2 2.1e-23 82.6 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCC68168.1 - 3e-10 39.2 30.0 3.9e-09 35.6 20.8 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 CCC68168.1 - 5.6e-10 38.1 6.7 5.6e-10 38.1 4.6 2.7 1 1 0 2 2 2 2 MFS/sugar transport protein ATP_synth_reg PF14960.1 CCC68168.1 - 0.12 11.5 0.8 0.27 10.4 0.1 2.0 2 0 0 2 2 2 0 ATP synthase regulation TPT PF03151.11 CCC68169.1 - 3.7e-20 72.1 8.6 3.7e-20 72.1 5.9 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CCC68169.1 - 9.8e-05 22.4 31.1 0.023 14.7 4.2 4.0 2 1 2 4 4 4 3 EamA-like transporter family PIRT PF15099.1 CCC68169.1 - 0.036 13.2 3.0 1.1 8.5 0.1 2.5 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Beta-TrCP_D PF12125.3 CCC68169.1 - 0.053 13.1 0.1 5.7 6.6 0.2 2.8 2 0 0 2 2 2 0 D domain of beta-TrCP UAA PF08449.6 CCC68169.1 - 0.16 10.8 25.4 1.5 7.6 17.6 2.4 1 1 0 1 1 1 0 UAA transporter family SART-1 PF03343.8 CCC68170.1 - 2.6e-55 187.9 60.7 2.5e-50 171.4 37.4 3.4 1 1 1 2 2 2 2 SART-1 family Nop PF01798.13 CCC68171.1 - 1.8e-58 196.1 2.1 3.2e-58 195.2 0.7 2.0 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 CCC68171.1 - 3e-27 94.1 0.5 6.7e-27 93.0 0.0 1.9 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 CCC68171.1 - 5.5e-19 68.0 1.8 5.5e-19 68.0 1.3 3.1 2 1 1 3 3 3 1 NOP5NT (NUC127) domain DUF4604 PF15377.1 CCC68171.1 - 0.17 12.0 46.0 0.34 11.1 31.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) GAGA_bind PF06217.7 CCC68171.1 - 7.1 6.5 26.2 2 8.2 16.0 1.7 2 0 0 2 2 2 0 GAGA binding protein-like family CTP_transf_1 PF01148.15 CCC68172.1 - 2.4e-19 69.9 15.4 2.2e-16 60.2 5.9 2.1 1 1 1 2 2 2 2 Cytidylyltransferase family DUF1212 PF06738.7 CCC68172.1 - 2.8 7.3 5.4 0.8 9.1 0.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1212) Ribosomal_L18ae PF01775.12 CCC68173.1 - 3.4e-45 152.9 4.0 3.4e-45 152.9 2.7 1.4 2 0 0 2 2 2 1 Ribosomal L18ae/LX protein domain DUF1057 PF06342.7 CCC68173.1 - 0.055 12.2 0.4 0.11 11.2 0.1 1.5 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) R3H-assoc PF13902.1 CCC68174.1 - 0.68 9.9 5.6 0.27 11.1 0.4 2.6 2 0 0 2 2 2 0 R3H-associated N-terminal domain Cation_efflux PF01545.16 CCC68176.1 - 3.8e-79 265.7 6.0 5.2e-79 265.2 4.2 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 CCC68176.1 - 0.00081 18.4 6.3 0.0058 15.6 4.4 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter Bac_rhodopsin PF01036.13 CCC68177.1 - 9.9e-58 195.0 20.2 1.2e-57 194.8 14.0 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 CCC68177.1 - 0.02 14.3 11.5 0.42 9.9 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2370 PF10176.4 CCC68177.1 - 0.063 12.6 0.1 0.063 12.6 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2370) Sulfate_transp PF00916.15 CCC68177.1 - 0.89 8.5 11.2 0.074 12.0 0.7 2.2 1 1 1 2 2 2 0 Sulfate transporter family RRM_1 PF00076.17 CCC68179.1 - 7.9e-23 79.8 1.6 7.8e-13 47.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC68179.1 - 7.8e-19 67.4 0.2 5.6e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC68179.1 - 2.5e-12 46.4 2.4 1.7e-05 24.5 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_transf_8 PF01501.15 CCC68180.1 - 5.1e-08 32.5 12.3 1.7e-06 27.5 8.5 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 zf-C3HC4_4 PF15227.1 CCC68183.1 - 5.2e-10 39.0 9.8 5.2e-10 39.0 6.8 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CCC68183.1 - 1.6e-08 34.0 9.4 1.6e-08 34.0 6.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCC68183.1 - 2.5e-07 30.3 7.4 2.5e-07 30.3 5.1 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 CCC68183.1 - 4.7e-07 29.4 3.2 1.1e-06 28.2 2.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 CCC68183.1 - 5.2e-07 29.2 5.9 5.2e-07 29.2 4.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC68183.1 - 1.9e-06 27.7 9.4 1.9e-06 27.7 6.5 2.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC68183.1 - 9.6e-06 25.2 7.3 9.6e-06 25.2 5.0 2.7 2 1 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 CCC68183.1 - 0.0058 16.4 1.7 0.0058 16.4 1.2 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 CCC68183.1 - 0.0086 15.8 10.5 0.28 11.0 0.2 2.7 2 1 0 2 2 2 2 Double zinc ribbon zf-rbx1 PF12678.2 CCC68183.1 - 0.0087 16.1 5.6 0.0087 16.1 3.9 2.4 2 1 0 2 2 2 1 RING-H2 zinc finger zf-ribbon_3 PF13248.1 CCC68183.1 - 0.028 13.6 0.6 0.028 13.6 0.4 2.9 3 0 0 3 3 2 0 zinc-ribbon domain zf-RING_3 PF14369.1 CCC68183.1 - 0.05 13.5 1.4 0.05 13.5 1.0 3.2 3 1 1 4 4 3 0 zinc-finger RRN7 PF11781.3 CCC68183.1 - 0.087 12.3 4.5 5.1 6.6 0.0 4.2 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-RING_4 PF14570.1 CCC68183.1 - 0.59 9.7 17.4 0.57 9.8 4.5 2.9 2 2 0 2 2 2 0 RING/Ubox like zinc-binding domain RNHCP PF12647.2 CCC68183.1 - 1.1 9.1 10.9 0.79 9.5 0.5 3.1 2 1 1 3 3 3 0 RNHCP domain Zn-ribbon_8 PF09723.5 CCC68183.1 - 3.4 7.6 12.0 9.3 6.3 1.2 3.5 2 1 1 3 3 3 0 Zinc ribbon domain zf-CHY PF05495.7 CCC68183.1 - 4.9 7.3 13.0 3.6 7.8 0.3 3.3 2 1 0 2 2 2 0 CHY zinc finger Glyco_transf_20 PF00982.16 CCC68184.1 - 1.7e-168 560.9 1.9 1.7e-168 560.9 1.3 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCC68184.1 - 1.2e-41 142.2 0.1 3.4e-41 140.7 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase CUE PF02845.11 CCC68185.1 - 1.7e-07 30.5 0.0 2.6e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 CUE domain SICA_C PF12879.2 CCC68185.1 - 0.069 13.0 1.4 0.078 12.8 1.0 1.2 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain WD40 PF00400.27 CCC68186.1 - 1.9e-32 109.9 3.2 5.4e-07 29.2 0.1 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CCC68186.1 - 2.9e-05 23.8 0.3 0.11 12.1 0.0 3.5 3 0 0 3 3 3 3 Eukaryotic translation initiation factor eIF2A Bac_rhodopsin PF01036.13 CCC68187.1 - 1.8e-59 200.7 15.6 2.1e-59 200.5 10.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 CCC68187.1 - 0.99 8.7 12.3 0.79 9.1 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Nup188 PF10487.4 CCC68188.1 - 2e-204 681.3 61.2 7e-203 676.2 29.1 2.3 1 1 1 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 PXA PF02194.10 CCC68189.1 - 3.7e-37 127.6 2.1 3.7e-37 127.6 1.4 2.2 3 0 0 3 3 3 1 PXA domain Nexin_C PF08628.7 CCC68189.1 - 1.2e-25 89.7 0.1 1.2e-25 89.7 0.1 2.2 2 0 0 2 2 2 1 Sorting nexin C terminal PX PF00787.19 CCC68189.1 - 6.8e-14 51.6 3.2 6.8e-14 51.6 2.2 2.9 3 0 0 3 3 3 1 PX domain SRP19 PF01922.12 CCC68190.1 - 1.6e-28 99.1 0.0 3.2e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 SRP19 protein Pribosyltran PF00156.22 CCC68191.1 - 6.2e-17 61.4 0.3 1.4e-16 60.3 0.2 1.6 2 0 0 2 2 2 1 Phosphoribosyl transferase domain zf-C3HC PF07967.8 CCC68192.1 - 1.5e-10 40.9 2.0 1.5e-10 40.9 1.4 2.7 2 2 1 3 3 3 1 C3HC zinc finger-like Rsm1 PF08600.5 CCC68192.1 - 4e-05 23.3 3.5 0.0012 18.6 0.1 3.4 3 0 0 3 3 3 1 Rsm1-like Sgf11 PF08209.6 CCC68192.1 - 0.079 12.2 1.9 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Oxidored_FMN PF00724.15 CCC68193.1 - 7.8e-123 409.8 0.0 8.9e-123 409.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF1892 PF08987.5 CCC68194.1 - 4e-42 142.8 6.5 4.4e-42 142.7 4.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1892) Zds_C PF08632.5 CCC68195.1 - 5.4e-33 112.1 1.7 1e-32 111.2 1.2 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term Ubie_methyltran PF01209.13 CCC68196.1 - 1.4e-96 322.0 0.3 1.7e-96 321.8 0.2 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 CCC68196.1 - 2.9e-11 43.1 0.0 3.9e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCC68196.1 - 4e-08 33.6 0.0 7.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC68196.1 - 2.7e-07 30.4 0.0 6.1e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC68196.1 - 8.2e-07 29.3 0.0 1.3e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCC68196.1 - 5.2e-06 26.8 0.0 8.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC68196.1 - 8.3e-05 23.1 0.0 0.00014 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CCC68196.1 - 0.0022 17.6 0.0 0.16 11.5 0.0 2.4 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 CCC68196.1 - 0.0049 16.5 0.0 0.0074 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Bul1_N PF04425.7 CCC68197.1 - 4.2e-171 569.3 5.7 4.2e-171 569.3 3.9 3.1 2 2 1 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 CCC68197.1 - 6.1e-102 340.4 18.6 6.1e-102 340.4 12.9 4.3 4 1 0 4 4 4 1 Bul1 C terminus Hexapep PF00132.19 CCC68198.1 - 1.5e-05 24.2 0.7 0.014 14.9 0.2 3.3 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CCC68198.1 - 0.00032 20.8 0.0 0.00053 20.1 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 CCC68198.1 - 0.014 13.9 1.4 0.21 10.1 0.1 2.0 1 1 1 2 2 2 0 L-fucokinase Synapsin PF02078.11 CCC68198.1 - 0.14 12.2 0.0 3.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Synapsin, N-terminal domain AAA PF00004.24 CCC68199.1 - 1.9e-42 144.6 0.0 3.4e-42 143.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCC68199.1 - 8.4e-07 29.1 0.1 6.3e-05 23.0 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 CCC68199.1 - 2.3e-06 27.3 0.1 6.3e-05 22.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCC68199.1 - 1.2e-05 25.2 0.0 2.6e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 CCC68199.1 - 3.7e-05 23.8 0.1 0.003 17.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCC68199.1 - 4.4e-05 22.6 0.0 8.9e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCC68199.1 - 0.00016 21.3 0.1 0.00034 20.3 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 CCC68199.1 - 0.00052 20.8 0.7 0.0013 19.5 0.1 2.1 2 1 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CCC68199.1 - 0.0012 18.4 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 CCC68199.1 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase TIP49 PF06068.8 CCC68199.1 - 0.0021 16.8 0.1 0.0038 15.9 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Mg_chelatase PF01078.16 CCC68199.1 - 0.0054 15.9 0.2 0.011 14.9 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CCC68199.1 - 0.0065 16.3 0.1 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCC68199.1 - 0.0067 16.7 0.1 0.049 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCC68199.1 - 0.0074 15.7 0.1 0.0074 15.7 0.1 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCC68199.1 - 0.0076 16.1 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 CCC68199.1 - 0.009 15.9 0.0 0.02 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CCC68199.1 - 0.01 15.4 0.3 0.021 14.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 CCC68199.1 - 0.013 14.5 0.1 0.086 11.9 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_25 PF13481.1 CCC68199.1 - 0.024 14.0 3.9 0.033 13.5 0.3 2.6 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.7 CCC68199.1 - 0.028 13.5 0.8 0.12 11.5 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin PhoH PF02562.11 CCC68199.1 - 0.034 13.3 0.2 0.068 12.3 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein Parvo_NS1 PF01057.12 CCC68199.1 - 0.063 12.1 0.1 0.13 11.1 0.1 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 CCC68199.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCC68199.1 - 0.098 12.3 0.1 0.34 10.5 0.0 1.9 1 1 1 2 2 2 0 NACHT domain AAA_11 PF13086.1 CCC68199.1 - 0.11 12.0 0.6 0.84 9.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CCC68199.1 - 0.12 11.8 0.1 0.57 9.6 0.0 2.0 2 1 0 2 2 2 0 Sigma-54 interaction domain NB-ARC PF00931.17 CCC68199.1 - 0.15 10.9 0.9 0.82 8.4 0.0 2.1 2 0 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.1 CCC68199.1 - 0.32 11.2 7.1 5.1 7.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain HIT PF01230.18 CCC68200.1 - 2.4e-21 76.0 0.1 5.7e-21 74.8 0.1 1.6 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 CCC68200.1 - 2.7e-14 53.3 2.0 8.6e-14 51.7 1.4 1.7 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding zf-C2H2_4 PF13894.1 CCC68200.1 - 0.0085 16.3 2.5 0.014 15.6 0.2 2.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CCC68200.1 - 0.067 13.3 2.0 0.11 12.5 0.7 2.0 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) HTH_16 PF12645.2 CCC68200.1 - 0.093 12.6 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF1882 PF08966.6 CCC68200.1 - 0.12 12.4 4.5 0.31 11.0 1.1 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF1882) TFR_dimer PF04253.10 CCC68201.1 - 2.2e-28 98.3 0.5 4e-28 97.4 0.3 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Rbsn PF11464.3 CCC68201.1 - 0.0023 17.4 0.2 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 Rabenosyn Rab binding domain Acetyltransf_1 PF00583.19 CCC68202.1 - 3.7e-13 49.3 0.0 5e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCC68202.1 - 1.5e-07 31.4 0.1 2.1e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCC68202.1 - 4.2e-06 26.8 0.0 4.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCC68202.1 - 5.9e-05 23.1 0.0 7.7e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCC68202.1 - 0.00061 19.7 0.0 0.00073 19.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCC68202.1 - 0.0023 17.6 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 CCC68202.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain EppA_BapA PF07268.6 CCC68202.1 - 0.032 13.9 0.4 0.062 12.9 0.3 1.6 1 0 0 1 1 1 0 Exported protein precursor (EppA/BapA) DUF3780 PF12635.2 CCC68202.1 - 0.13 11.7 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3780) DUF2962 PF11176.3 CCC68203.1 - 1.7e-48 164.1 4.8 2e-48 163.8 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Rhodanese PF00581.15 CCC68204.1 - 1.1e-19 70.8 0.0 1.3e-10 41.6 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain HAD_2 PF13419.1 CCC68204.1 - 0.016 15.4 0.0 0.041 14.0 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase ROK PF00480.15 CCC68204.1 - 0.089 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 ROK family Clp1 PF06807.9 CCC68205.1 - 2.9e-21 76.1 0.0 4.8e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 CCC68205.1 - 1e-08 34.9 0.0 2e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 CCC68205.1 - 0.00067 19.5 0.1 0.0094 15.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 CCC68205.1 - 0.00079 18.9 0.0 0.0017 17.8 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 CCC68205.1 - 0.0026 18.5 0.0 0.0082 16.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain ATP_bind_1 PF03029.12 CCC68205.1 - 0.0028 17.2 0.1 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 CCC68205.1 - 0.0061 16.4 0.2 0.02 14.8 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 CCC68205.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 CCC68205.1 - 0.024 14.7 0.4 0.24 11.5 0.2 2.4 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 CCC68205.1 - 0.028 13.4 0.0 0.6 9.0 0.0 2.2 2 0 0 2 2 2 0 Septin AAA PF00004.24 CCC68205.1 - 0.039 14.1 0.1 1 9.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 CCC68205.1 - 0.039 13.5 0.1 0.13 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCC68205.1 - 0.052 13.8 0.1 0.16 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CCC68205.1 - 0.062 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family FeoB_N PF02421.13 CCC68205.1 - 0.11 11.7 0.4 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B Apc5 PF12862.2 CCC68206.1 - 5.6e-26 90.2 5.4 5.6e-26 90.2 3.7 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 NAD_binding_9 PF13454.1 CCC68206.1 - 0.098 12.4 0.0 0.34 10.6 0.0 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding SWI-SNF_Ssr4 PF08549.5 CCC68207.1 - 0.96 7.6 10.0 1.3 7.1 6.9 1.2 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) adh_short PF00106.20 CCC68209.1 - 2.9e-12 46.8 0.0 3.7e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCC68209.1 - 1.3e-06 28.3 0.0 5.8e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 CCC68209.1 - 0.0017 17.8 0.0 0.0027 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 CCC68209.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 KR domain NAD_binding_10 PF13460.1 CCC68209.1 - 0.055 13.4 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding tRNA-synt_1 PF00133.17 CCC68210.1 - 3.8e-45 154.0 0.0 1.4e-35 122.4 0.0 2.5 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CCC68210.1 - 7.2e-21 74.2 0.5 5.3e-11 41.7 0.0 4.2 4 0 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CCC68210.1 - 1.5e-13 50.8 0.0 4.3e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CCC68210.1 - 4.3e-07 29.3 1.4 1e-06 28.0 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain YEATS PF03366.11 CCC68212.1 - 2.8e-24 84.6 0.0 4.4e-24 84.0 0.0 1.3 1 0 0 1 1 1 1 YEATS family Alpha_L_fucos PF01120.12 CCC68213.1 - 0.00074 18.5 0.3 0.00091 18.2 0.2 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase DUF2815 PF10991.3 CCC68213.1 - 0.043 13.3 0.1 0.056 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2815) YqeY PF09424.5 CCC68214.1 - 7.5e-20 71.2 5.6 9.8e-20 70.8 3.9 1.2 1 0 0 1 1 1 1 Yqey-like protein Rapamycin_bind PF08771.6 CCC68214.1 - 0.03 14.4 2.3 0.059 13.4 1.3 1.7 1 1 0 1 1 1 0 Rapamycin binding domain PRANC PF09372.5 CCC68214.1 - 0.037 14.0 3.6 0.67 9.9 0.6 2.4 1 1 1 2 2 2 0 PRANC domain tRNA_NucTran2_2 PF13735.1 CCC68214.1 - 0.17 11.6 4.3 0.11 12.3 1.3 1.8 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Pox_A3L PF05288.6 CCC68214.1 - 0.23 11.1 2.0 0.79 9.5 0.1 2.4 2 0 0 2 2 2 0 Poxvirus A3L Protein RFC1 PF08519.7 CCC68214.1 - 0.95 9.2 5.9 0.57 9.9 2.5 1.7 1 1 1 2 2 2 0 Replication factor RFC1 C terminal domain GRAB PF10375.4 CCC68215.1 - 1e-06 28.1 1.2 2.4e-06 26.9 0.8 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain CENP-F_leu_zip PF10473.4 CCC68215.1 - 0.0012 18.6 54.5 0.003 17.4 20.9 5.1 1 1 4 5 5 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Imm42 PF15601.1 CCC68215.1 - 0.0019 17.6 3.7 0.0019 17.6 2.6 3.1 3 1 1 4 4 4 1 Immunity protein 42 IncA PF04156.9 CCC68215.1 - 0.0032 17.0 24.2 0.0032 17.0 16.7 4.6 1 1 3 4 4 4 2 IncA protein TMF_DNA_bd PF12329.3 CCC68215.1 - 0.005 16.6 13.7 0.005 16.6 9.5 7.4 4 3 3 7 7 7 3 TATA element modulatory factor 1 DNA binding CENP-Q PF13094.1 CCC68215.1 - 0.016 15.2 5.9 0.016 15.2 4.1 5.0 1 1 4 5 5 5 0 CENP-Q, a CENPA-CAD centromere complex subunit GAS PF13851.1 CCC68215.1 - 0.17 11.0 97.4 0.1 11.7 15.1 4.7 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding DUF3407 PF11887.3 CCC68215.1 - 0.99 8.6 6.2 0.87 8.8 2.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3407) Filament PF00038.16 CCC68215.1 - 2 7.7 76.5 0.17 11.3 12.3 4.0 1 1 2 3 3 3 0 Intermediate filament protein Rootletin PF15035.1 CCC68215.1 - 2.7 7.9 70.6 0.06 13.3 21.4 4.5 1 1 3 4 4 4 0 Ciliary rootlet component, centrosome cohesion DASH_Dam1 PF08653.5 CCC68215.1 - 3.6 7.4 19.0 0.42 10.4 0.8 5.1 5 1 0 5 5 5 0 DASH complex subunit Dam1 Reo_sigmaC PF04582.7 CCC68215.1 - 7.9 5.5 32.6 0.34 10.0 4.9 3.9 1 1 3 4 4 4 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 CCC68215.1 - 9.2 3.4 79.6 0.029 11.7 38.6 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) RFC1 PF08519.7 CCC68216.1 - 1.5e-62 209.9 0.3 1.5e-62 209.9 0.2 2.6 3 0 0 3 3 3 1 Replication factor RFC1 C terminal domain AAA PF00004.24 CCC68216.1 - 1.6e-12 47.7 0.0 6.8e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 CCC68216.1 - 1.5e-10 41.0 0.1 1.6e-09 37.7 0.0 2.7 3 0 0 3 3 2 1 BRCA1 C Terminus (BRCT) domain Rad17 PF03215.10 CCC68216.1 - 1.7e-09 36.9 0.1 1.4e-06 27.2 0.0 2.2 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 CCC68216.1 - 1.8e-06 28.1 0.0 1.5e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCC68216.1 - 4.6e-06 27.4 0.0 5e-05 24.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCC68216.1 - 1.3e-05 24.4 0.0 2.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCC68216.1 - 0.0018 17.9 0.0 0.0046 16.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 CCC68216.1 - 0.0019 18.1 0.0 0.034 14.1 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 CCC68216.1 - 0.0021 17.9 0.0 0.0056 16.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCC68216.1 - 0.0022 18.3 0.4 0.012 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCC68216.1 - 0.0028 17.7 0.0 0.0097 16.0 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 CCC68216.1 - 0.0066 16.3 0.0 0.063 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain PTCB-BRCT PF12738.2 CCC68216.1 - 0.0078 16.0 0.0 0.029 14.2 0.0 2.0 1 0 0 1 1 1 1 twin BRCT domain NACHT PF05729.7 CCC68216.1 - 0.072 12.7 0.0 0.45 10.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 CCC68216.1 - 0.098 12.3 0.0 0.35 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PPP5 PF08321.7 CCC68217.1 - 0.00097 19.1 0.1 1 9.4 0.0 2.2 2 0 0 2 2 2 2 PPP5 TPR repeat region Acyl_transf_1 PF00698.16 CCC68219.1 - 0.0033 16.8 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain Mito_carr PF00153.22 CCC68220.1 - 3.1e-68 225.5 1.1 4.2e-25 87.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 CCC68220.1 - 0.084 12.9 0.0 2 8.4 0.0 2.7 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF2407_C PF13373.1 CCC68221.1 - 1.1e-43 148.5 1.8 2e-43 147.6 1.2 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 CCC68221.1 - 1.1e-20 73.5 0.2 2e-20 72.7 0.1 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Syntaxin PF00804.20 CCC68221.1 - 0.037 14.1 0.1 0.083 13.0 0.1 1.6 1 0 0 1 1 1 0 Syntaxin SICA_alpha PF12887.2 CCC68221.1 - 0.13 12.0 0.0 0.63 9.7 0.0 2.0 2 0 0 2 2 2 0 SICA extracellular alpha domain RNA_pol_Rpb8 PF03870.10 CCC68222.1 - 2.5e-47 160.5 0.1 2.8e-47 160.3 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 NifU_N PF01592.11 CCC68223.1 - 1.9e-52 176.5 0.2 2.2e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain LRR_4 PF12799.2 CCC68224.1 - 0.0044 16.6 20.3 0.011 15.3 2.9 5.9 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CCC68224.1 - 0.62 10.2 9.6 89 3.6 0.2 6.6 6 0 0 6 6 6 0 Leucine Rich repeat DUF1691 PF07950.6 CCC68225.1 - 8.1e-20 70.8 6.8 1.3e-11 44.4 1.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) Sdh_cyt PF01127.17 CCC68225.1 - 0.045 13.5 6.2 0.03 14.1 1.7 2.2 2 0 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Mmp37 PF09139.6 CCC68226.1 - 3.2e-106 355.1 7.5 7.9e-97 324.2 1.1 2.1 1 1 1 2 2 2 2 Mitochondrial matrix Mmp37 WD40 PF00400.27 CCC68227.1 - 4.6e-07 29.4 5.4 0.0042 16.9 0.2 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40 PF00400.27 CCC68228.1 - 2.4e-07 30.3 10.3 0.0041 16.9 0.2 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Pkinase PF00069.20 CCC68229.1 - 1.7e-68 230.5 0.0 2.6e-68 230.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68229.1 - 4e-35 121.1 0.0 8.3e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC68229.1 - 2.9e-09 36.3 0.0 5.1e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CCC68229.1 - 0.023 13.5 0.0 0.043 12.6 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 CCC68229.1 - 0.033 13.9 0.0 0.075 12.7 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 CCC68229.1 - 0.035 13.1 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GrpE PF01025.14 CCC68230.1 - 1.4e-49 167.8 9.9 1.8e-49 167.4 6.9 1.1 1 0 0 1 1 1 1 GrpE Uds1 PF15456.1 CCC68230.1 - 0.0013 18.7 4.9 0.0025 17.7 3.4 1.5 1 0 0 1 1 1 1 Up-regulated During Septation Atg14 PF10186.4 CCC68230.1 - 0.054 12.4 4.0 0.075 11.9 2.7 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 V_ATPase_I PF01496.14 CCC68230.1 - 0.11 10.3 4.4 0.11 10.3 3.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.3 CCC68230.1 - 0.11 11.1 4.6 0.14 10.7 3.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Toxin_trans PF07952.7 CCC68230.1 - 0.28 10.0 4.9 0.36 9.6 3.4 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain YqfQ PF14181.1 CCC68230.1 - 1.2 9.1 5.1 2 8.4 3.5 1.4 1 0 0 1 1 1 0 YqfQ-like protein OmpH PF03938.9 CCC68230.1 - 3.2 7.6 12.7 5.1 7.0 8.8 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) IncA PF04156.9 CCC68230.1 - 3.9 7.0 13.3 8.2 5.9 9.2 1.6 1 1 0 1 1 1 0 IncA protein ARD PF03079.9 CCC68230.1 - 6.3 6.7 9.2 17 5.3 6.4 1.7 1 1 0 1 1 1 0 ARD/ARD' family Pkinase PF00069.20 CCC68231.1 - 1.6e-65 220.8 0.0 2.8e-65 220.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68231.1 - 1.8e-38 132.0 0.0 2.9e-38 131.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC68231.1 - 8e-08 31.5 0.0 2.5e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCC68231.1 - 0.0038 16.3 0.1 0.0097 14.9 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCC68231.1 - 0.006 15.9 0.0 0.024 13.9 0.0 2.0 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 CCC68231.1 - 0.017 14.8 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1899 PF08953.6 CCC68231.1 - 0.14 11.8 1.6 7.8 6.2 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1899) Ribosomal_L35Ae PF01247.13 CCC68232.1 - 1.8e-41 139.8 1.0 2e-41 139.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CCC68232.1 - 0.008 16.0 0.0 3.6 7.5 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain chaperone_DMP PF10448.4 CCC68233.1 - 5.5e-16 58.7 1.4 6.3e-16 58.5 1.0 1.1 1 0 0 1 1 1 1 20S proteasome chaperone DHFR_1 PF00186.14 CCC68234.1 - 2.8e-29 101.7 0.0 4.8e-29 101.0 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase Trm56 PF01994.11 CCC68234.1 - 0.083 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 tRNA ribose 2'-O-methyltransferase, aTrm56 Oxysterol_BP PF01237.13 CCC68235.1 - 4.7e-84 281.8 0.9 5.9e-84 281.5 0.6 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein MA3 PF02847.12 CCC68236.1 - 0.012 15.3 0.1 0.023 14.3 0.1 1.5 1 0 0 1 1 1 0 MA3 domain ABC_membrane_2 PF06472.10 CCC68237.1 - 2e-85 286.3 6.8 3.2e-85 285.6 4.7 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 CCC68237.1 - 1.4e-13 51.3 0.0 4.5e-13 49.6 0.0 1.9 1 1 0 1 1 1 1 ABC transporter bPH_3 PF14470.1 CCC68237.1 - 0.0023 18.1 1.6 0.82 9.9 0.1 3.0 3 0 0 3 3 3 2 Bacterial PH domain SMC_N PF02463.14 CCC68237.1 - 0.0039 16.4 0.0 0.058 12.6 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 CCC68237.1 - 0.071 13.0 0.3 0.65 9.9 0.2 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 CCC68237.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain DUF1749 PF08538.5 CCC68238.1 - 1.3e-96 323.0 0.0 1.4e-96 322.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 CCC68238.1 - 1.6e-11 44.5 0.0 1.9e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCC68238.1 - 8e-08 32.1 0.0 9.2e-07 28.7 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC68238.1 - 0.00016 21.3 0.1 0.00031 20.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCC68238.1 - 0.00034 19.9 0.0 0.00094 18.4 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Ndr PF03096.9 CCC68238.1 - 0.0018 16.8 0.0 0.0025 16.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF2305 PF10230.4 CCC68238.1 - 0.0037 16.7 1.0 0.013 14.9 0.1 2.0 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 CCC68238.1 - 0.0084 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase SPA PF08616.5 CCC68238.1 - 0.015 14.9 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Stabilization of polarity axis Abhydrolase_2 PF02230.11 CCC68238.1 - 0.038 13.4 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase COesterase PF00135.23 CCC68238.1 - 0.05 12.3 0.0 0.072 11.7 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family LCAT PF02450.10 CCC68238.1 - 0.075 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.7 CCC68238.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF2023 PF09633.5 CCC68240.1 - 0.019 14.8 1.4 0.53 10.2 0.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2023) Utp11 PF03998.8 CCC68240.1 - 0.067 13.0 0.4 0.067 13.0 0.3 1.9 1 1 1 2 2 2 0 Utp11 protein BCDHK_Adom3 PF10436.4 CCC68240.1 - 0.074 12.5 1.4 0.11 12.0 0.9 1.3 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase DUF1250 PF06855.7 CCC68240.1 - 0.085 12.3 0.1 0.25 10.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1250) DASH_Dad3 PF08656.5 CCC68240.1 - 0.1 12.2 2.2 1 9.0 0.2 2.5 1 1 1 2 2 2 0 DASH complex subunit Dad3 DASH_Duo1 PF08651.5 CCC68240.1 - 0.18 11.4 4.6 0.5 9.9 0.4 2.5 1 1 1 2 2 2 0 DASH complex subunit Duo1 Mur_ligase_M PF08245.7 CCC68243.1 - 2.3e-05 24.5 2.3 6.2e-05 23.1 0.2 2.7 2 2 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.16 CCC68243.1 - 0.028 14.4 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Mur ligase family, glutamate ligase domain UXS1_N PF11803.3 CCC68243.1 - 0.087 12.6 0.8 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 UDP-glucuronate decarboxylase N-terminal TruD PF01142.13 CCC68245.1 - 1.1e-62 211.9 0.6 1.4e-58 198.4 0.0 4.3 3 1 0 3 3 3 2 tRNA pseudouridine synthase D (TruD) MOZ_SAS PF01853.13 CCC68246.1 - 4.1e-89 296.8 0.5 6.1e-89 296.2 0.3 1.3 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 CCC68246.1 - 2.1e-22 78.5 0.2 4.7e-22 77.4 0.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 CCC68246.1 - 0.031 14.2 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family DAGAT PF03982.8 CCC68247.1 - 3.8e-83 278.5 1.9 2.5e-72 243.1 0.1 2.1 2 0 0 2 2 2 2 Diacylglycerol acyltransferase Rer1 PF03248.8 CCC68247.1 - 0.0048 16.5 0.5 0.04 13.5 0.1 2.1 2 0 0 2 2 2 1 Rer1 family Glutaredoxin PF00462.19 CCC68248.1 - 0.014 15.3 0.0 0.031 14.2 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin UbiA PF01040.13 CCC68248.1 - 0.05 12.8 0.1 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 UbiA prenyltransferase family YEATS PF03366.11 CCC68249.1 - 1.6e-21 75.8 0.1 2.9e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 YEATS family WD40 PF00400.27 CCC68250.1 - 3.8e-38 127.9 21.5 1.7e-08 34.0 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Dynamin_N PF00350.18 CCC68251.1 - 1.5e-42 145.2 1.7 2.4e-42 144.6 0.1 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 CCC68251.1 - 1.8e-05 24.6 0.2 0.0017 18.3 0.2 3.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCC68251.1 - 0.00093 19.6 0.0 0.0039 17.6 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 CCC68251.1 - 0.019 14.9 0.1 0.088 12.7 0.1 2.2 1 1 0 1 1 1 0 AAA ATPase domain Bd3614_N PF14442.1 CCC68251.1 - 1.7 8.6 4.1 3 7.8 2.8 1.4 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal NOA36 PF06524.7 CCC68251.1 - 3.6 6.7 5.6 6.5 5.9 3.9 1.3 1 0 0 1 1 1 0 NOA36 protein RNA_pol_N PF01194.12 CCC68252.1 - 2.1e-29 101.3 0.5 2.4e-29 101.1 0.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit YhfH PF14149.1 CCC68252.1 - 0.068 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 YhfH-like protein Chordopox_RPO7 PF05864.7 CCC68252.1 - 0.086 12.9 0.4 0.11 12.5 0.3 1.3 1 1 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) NAPRTase PF04095.11 CCC68253.1 - 1.1e-63 214.8 0.0 1.4e-63 214.4 0.0 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family RNA_pol_Rpb2_6 PF00562.23 CCC68254.1 - 5.2e-121 404.0 0.4 5.2e-121 404.0 0.3 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCC68254.1 - 1.2e-61 207.1 1.4 2.4e-61 206.1 1.0 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCC68254.1 - 9.9e-42 142.5 2.8 2.5e-41 141.2 2.0 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCC68254.1 - 2.1e-30 104.7 0.1 6.6e-30 103.2 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CCC68254.1 - 1e-26 92.5 0.2 3.9e-26 90.6 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CCC68254.1 - 6.8e-19 67.3 0.0 1.8e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CCC68254.1 - 4.6e-12 45.7 0.1 1.4e-11 44.1 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Baculo_Y142 PF04913.7 CCC68254.1 - 0.00097 17.6 0.1 0.0022 16.4 0.1 1.5 1 0 0 1 1 1 1 Baculovirus Y142 protein Noc2 PF03715.8 CCC68255.1 - 4.9e-128 426.1 9.9 5.2e-128 426.0 4.3 2.4 2 0 0 2 2 2 1 Noc2p family DUF2765 PF10963.3 CCC68255.1 - 0.0093 15.8 0.5 0.044 13.7 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2765) MMR_HSR1 PF01926.18 CCC68256.1 - 4.8e-09 36.1 2.1 1.6e-08 34.5 1.5 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCC68256.1 - 5.7e-06 25.6 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCC68256.1 - 0.0028 17.0 0.3 0.65 9.3 0.0 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CCC68256.1 - 0.0039 16.4 0.1 0.02 14.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B ABC_tran PF00005.22 CCC68256.1 - 0.0071 16.6 0.1 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 CCC68256.1 - 0.0084 15.6 0.1 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Miro PF08477.8 CCC68256.1 - 0.0099 16.3 0.2 0.037 14.5 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 CCC68256.1 - 0.01 15.6 1.8 0.21 11.3 0.1 3.0 3 0 0 3 3 3 0 Dynamin family AAA_17 PF13207.1 CCC68256.1 - 0.14 13.0 0.8 0.74 10.6 0.1 2.5 2 2 0 2 2 2 0 AAA domain DEAD PF00270.24 CCC68257.1 - 2.3e-46 157.3 0.0 6.4e-45 152.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC68257.1 - 2.3e-27 94.6 0.2 5.1e-27 93.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CCC68257.1 - 0.038 13.0 0.0 0.079 12.0 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 CCC68257.1 - 0.076 11.4 0.0 0.22 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1253) IGPD PF00475.13 CCC68258.1 - 3.3e-60 202.1 0.5 8.9e-60 200.7 0.3 1.6 2 0 0 2 2 2 1 Imidazoleglycerol-phosphate dehydratase SpoU_methylase PF00588.14 CCC68259.1 - 4.3e-26 91.4 0.0 7.2e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 CCC68259.1 - 4.2e-14 52.4 0.0 7.8e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Zip PF02535.17 CCC68259.1 - 0.26 10.2 0.5 0.36 9.8 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Col_cuticle_N PF01484.12 CCC68260.1 - 0.2 11.3 0.2 0.45 10.2 0.1 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain Peptidase_C14 PF00656.17 CCC68261.1 - 1.1e-70 238.2 0.1 1.4e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Radical_SAM PF04055.16 CCC68262.1 - 1e-13 51.7 0.0 1.9e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily DUF4131 PF13567.1 CCC68263.1 - 0.0059 16.0 0.4 0.0083 15.5 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) OST3_OST6 PF04756.8 CCC68263.1 - 0.021 14.3 0.2 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 OST3 / OST6 family Kinetocho_Slk19 PF12709.2 CCC68264.1 - 6.4e-29 99.8 15.5 6.4e-29 99.8 10.7 10.2 1 1 6 9 9 9 2 Central kinetochore-associated IncA PF04156.9 CCC68264.1 - 0.4 10.2 100.6 0.04 13.4 14.3 5.7 1 1 4 5 5 5 0 IncA protein Reo_sigmaC PF04582.7 CCC68264.1 - 0.43 9.7 34.7 0.054 12.6 6.1 4.3 1 1 3 4 4 4 0 Reovirus sigma C capsid protein DUF869 PF05911.6 CCC68264.1 - 0.72 8.0 99.9 0.86 7.7 28.2 3.2 1 1 2 3 3 3 0 Plant protein of unknown function (DUF869) Myosin_tail_1 PF01576.14 CCC68264.1 - 0.78 7.3 113.9 1.3 6.6 31.9 2.5 1 1 1 2 2 2 0 Myosin tail Filament PF00038.16 CCC68264.1 - 2.8 7.3 95.8 0.21 11.0 31.7 3.9 1 1 2 3 3 3 0 Intermediate filament protein PEX11 PF05648.9 CCC68265.1 - 2.7e-06 26.8 3.2 1e-05 24.9 2.2 1.9 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) PDH PF02153.12 CCC68267.1 - 1.3e-07 30.7 0.0 1.8e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase 2-Hacid_dh_C PF02826.14 CCC68267.1 - 0.00017 20.8 0.0 0.00032 19.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CCC68267.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CCC68267.1 - 0.0011 19.3 0.0 0.0021 18.4 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 CCC68267.1 - 0.0034 16.8 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 CCC68267.1 - 0.0066 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CCC68267.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.7 CCC68267.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Rpp20 PF12328.3 CCC68268.1 - 4.8e-29 100.8 5.1 3.7e-27 94.7 3.6 2.1 1 1 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 CCC68268.1 - 6.7e-17 60.8 0.2 1.1e-16 60.2 0.1 1.3 1 0 0 1 1 1 1 Alba Pex24p PF06398.6 CCC68269.1 - 7.9e-38 130.1 16.7 9.8e-38 129.8 11.6 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin HSP70 PF00012.15 CCC68270.1 - 3.7e-178 593.2 3.5 3.7e-178 593.2 2.4 1.8 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 CCC68270.1 - 2.3e-10 39.5 0.1 4.3e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 CCC68270.1 - 0.0002 21.1 5.1 0.0011 18.7 0.5 3.4 2 2 0 2 2 2 1 Cell division protein FtsA Trans_reg_C PF00486.23 CCC68270.1 - 0.037 13.9 0.0 0.17 11.8 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal AHS1 PF02682.11 CCC68270.1 - 0.071 12.5 0.0 0.24 10.8 0.0 1.9 1 0 0 1 1 1 0 Allophanate hydrolase subunit 1 Ribosomal_60s PF00428.14 CCC68270.1 - 2.1 8.8 18.5 0.92 9.9 10.2 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein NPL4 PF05021.10 CCC68271.1 - 2.9e-124 414.1 0.0 3.8e-124 413.8 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 CCC68271.1 - 1.1e-73 245.7 1.1 1.7e-73 245.0 0.8 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 CCC68271.1 - 1.1e-06 28.8 0.0 3.4e-06 27.2 0.0 1.9 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Sec66 PF09802.4 CCC68272.1 - 1.4e-72 243.1 2.6 1.6e-72 242.9 1.8 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 Tubulin_3 PF14881.1 CCC68272.1 - 0.051 13.0 0.1 0.11 11.9 0.0 1.5 1 1 0 1 1 1 0 Tubulin domain GYF PF02213.11 CCC68273.1 - 1.3e-18 66.3 0.2 3.5e-18 64.9 0.1 1.8 1 0 0 1 1 1 1 GYF domain Pyrid_oxidase_2 PF13883.1 CCC68273.1 - 0.65 9.7 7.6 0.035 13.8 1.0 2.0 2 0 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase Asp-B-Hydro_N PF05279.6 CCC68273.1 - 0.83 9.4 26.6 1.2 8.9 18.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region MAP7 PF05672.6 CCC68273.1 - 1 8.7 36.5 1.6 8.0 25.3 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family UMP1 PF05348.6 CCC68274.1 - 2.8e-37 127.5 0.4 3.5e-37 127.2 0.2 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 WD40 PF00400.27 CCC68275.1 - 4.8e-37 124.5 16.3 1.1e-08 34.6 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 CCC68275.1 - 0.00011 21.9 0.0 0.79 9.4 0.0 3.3 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 CCC68275.1 - 0.00042 19.2 0.0 0.0073 15.1 0.0 2.7 2 1 0 3 3 3 1 Coatomer WD associated region PD40 PF07676.7 CCC68275.1 - 0.00065 19.3 0.1 7.1 6.4 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 CCC68275.1 - 0.0044 15.3 0.0 1.3 7.2 0.0 2.4 1 1 1 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 CCC68275.1 - 0.023 12.8 0.2 1.4 6.9 0.0 2.5 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Hira PF07569.6 CCC68275.1 - 0.035 13.3 2.7 10 5.2 0.2 3.8 3 1 1 4 4 4 0 TUP1-like enhancer of split SUKH_6 PF14568.1 CCC68275.1 - 0.14 12.6 0.4 1.6 9.2 0.0 2.5 2 1 1 3 3 3 0 SMI1-KNR4 cell-wall Proteasome_A_N PF10584.4 CCC68275.1 - 0.16 11.3 0.1 2.9 7.2 0.0 2.5 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature Pantoate_transf PF02548.10 CCC68276.1 - 2.6e-95 318.4 0.0 3.2e-95 318.1 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 CCC68276.1 - 8.6e-07 28.4 0.0 1.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase DUF433 PF04255.9 CCC68276.1 - 0.093 12.1 0.0 0.4 10.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF433) PAXNEB PF05625.6 CCC68277.1 - 5.4e-106 354.4 0.3 6.7e-106 354.1 0.2 1.1 1 0 0 1 1 1 1 PAXNEB protein Romo1 PF10247.4 CCC68278.1 - 3.6e-27 94.3 9.2 4.5e-27 94.0 6.3 1.1 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 tRNA-synt_1b PF00579.20 CCC68279.1 - 1.1e-76 257.7 0.0 1.7e-76 257.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TelA PF05816.6 CCC68279.1 - 0.042 12.5 0.4 0.089 11.4 0.1 1.6 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) Radical_SAM_N PF08497.5 CCC68279.1 - 0.077 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Radical SAM N-terminal ABC2_membrane_4 PF12730.2 CCC68280.1 - 0.049 12.7 5.7 0.058 12.5 3.9 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2207 PF09972.4 CCC68280.1 - 0.1 11.1 0.7 0.1 11.1 0.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CbiQ PF02361.11 CCC68280.1 - 0.11 11.9 1.7 0.12 11.9 1.2 1.0 1 0 0 1 1 1 0 Cobalt transport protein DUF4131 PF13567.1 CCC68280.1 - 0.12 11.8 1.2 0.13 11.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) 2TM PF13239.1 CCC68280.1 - 0.15 12.1 3.4 0.17 11.9 2.3 1.1 1 0 0 1 1 1 0 2TM domain Phlebovirus_G1 PF07243.6 CCC68280.1 - 1.1 7.2 2.8 1.2 7.1 1.9 1.0 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 Novirhabdo_Nv PF05554.6 CCC68281.1 - 0.036 13.6 0.3 0.32 10.5 0.0 2.1 2 0 0 2 2 2 0 Viral hemorrhagic septicemia virus non-virion protein Abhydrolase_1 PF00561.15 CCC68282.1 - 5.8e-31 107.8 0.0 9.2e-31 107.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCC68282.1 - 4.3e-14 52.9 0.0 6.5e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCC68282.1 - 5.7e-10 39.1 0.0 2.8e-09 36.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 CCC68282.1 - 0.0042 16.3 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Peptidase_S9 PF00326.16 CCC68282.1 - 0.0086 15.3 0.0 1.5 8.0 0.0 2.4 2 0 0 2 2 2 2 Prolyl oligopeptidase family Cutinase PF01083.17 CCC68282.1 - 0.014 15.0 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase Dynamin_N PF00350.18 CCC68283.1 - 6e-17 61.9 0.4 6e-17 61.9 0.3 2.7 4 0 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.18 CCC68283.1 - 9.4e-08 32.0 1.7 4.2e-07 29.9 0.1 2.9 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCC68283.1 - 1.1e-06 28.2 2.2 1e-05 25.0 0.2 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PPV_E1_C PF00519.12 CCC68283.1 - 0.0077 14.8 0.1 0.017 13.7 0.1 1.5 1 1 0 1 1 1 1 Papillomavirus helicase Miro PF08477.8 CCC68283.1 - 0.021 15.3 0.2 0.17 12.3 0.0 2.7 2 1 1 3 3 3 0 Miro-like protein AAA_17 PF13207.1 CCC68283.1 - 0.21 12.4 2.9 3.2 8.5 0.0 3.6 4 1 0 4 4 4 0 AAA domain NOGCT PF08155.6 CCC68284.1 - 1e-27 95.5 2.0 2.6e-27 94.2 1.4 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 CCC68284.1 - 2.6e-27 94.4 0.4 5.9e-27 93.3 0.3 1.7 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 CCC68284.1 - 4.1e-16 58.9 0.0 1.1e-15 57.5 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCC68284.1 - 1.4e-07 30.9 0.0 3.3e-07 29.7 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 CCC68284.1 - 0.00037 19.7 0.3 0.0016 17.6 0.0 2.1 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCC68284.1 - 0.0029 18.0 0.3 0.0085 16.5 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 CCC68284.1 - 0.021 14.6 0.0 10 5.9 0.0 2.8 1 1 1 2 2 2 0 Dynamin family AAA_29 PF13555.1 CCC68284.1 - 0.061 12.8 0.0 14 5.3 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain MFS_1 PF07690.11 CCC68285.1 - 9.2e-48 162.7 25.2 9.2e-48 162.7 17.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCC68285.1 - 1.9e-19 69.5 3.8 1.9e-19 69.5 2.6 2.5 3 0 0 3 3 3 2 Sugar (and other) transporter Ribosomal_S6e PF01092.14 CCC68286.1 - 6.3e-26 90.5 0.1 1.5e-25 89.3 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e Cadherin_C PF01049.12 CCC68286.1 - 0.089 12.8 0.2 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic region SRF-TF PF00319.13 CCC68287.1 - 6.4e-22 76.5 0.1 1.1e-21 75.7 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ceramidase PF05875.7 CCC68288.1 - 3.8e-89 298.3 13.2 4.4e-89 298.0 9.1 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.6 CCC68288.1 - 0.057 13.0 1.3 0.23 11.2 0.9 2.1 1 0 0 1 1 1 0 Trp-operon Leader Peptide Radical_SAM PF04055.16 CCC68289.1 - 2.6e-15 56.9 0.3 7.7e-15 55.4 0.0 1.9 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 CCC68289.1 - 2.1e-12 46.8 0.1 7.9e-12 45.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family MBA1 PF07961.6 CCC68291.1 - 1.5e-95 318.5 0.2 1.9e-95 318.1 0.1 1.0 1 0 0 1 1 1 1 MBA1-like protein Glyco_transf_20 PF00982.16 CCC68291.1 - 0.03 12.7 0.0 0.042 12.3 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 20 BRO1 PF03097.13 CCC68292.1 - 1.6e-91 306.9 11.2 1.6e-91 306.9 7.7 2.0 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 CCC68292.1 - 8.4e-43 146.4 13.4 8.4e-43 146.4 9.3 1.9 2 1 0 2 2 2 1 ALIX V-shaped domain binding to HIV tRNA_int_end_N2 PF12928.2 CCC68293.1 - 1.2e-18 66.3 0.0 2e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term UPF0016 PF01169.14 CCC68294.1 - 2.8e-38 129.9 18.6 1.2e-20 73.3 2.7 2.4 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 TerC PF03741.11 CCC68294.1 - 1.6 8.1 10.5 0.077 12.4 1.2 2.3 2 0 0 2 2 2 0 Integral membrane protein TerC family cwf18 PF08315.7 CCC68295.1 - 0.0088 16.5 12.8 0.017 15.6 8.9 1.5 1 1 0 1 1 1 1 cwf18 pre-mRNA splicing factor Glyco_hydro_77 PF02446.12 CCC68295.1 - 0.063 11.8 0.4 0.072 11.6 0.3 1.1 1 0 0 1 1 1 0 4-alpha-glucanotransferase DUF3731 PF12531.3 CCC68295.1 - 0.42 10.1 4.1 0.15 11.5 1.2 1.4 2 0 0 2 2 2 0 DNA-K related protein ELH PF02323.10 CCC68295.1 - 2.4 7.2 9.7 4.2 6.4 0.9 2.1 2 0 0 2 2 2 0 Egg-laying hormone precursor Ribosomal_S4 PF00163.14 CCC68296.1 - 5.3e-26 90.8 1.1 8.7e-26 90.1 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCC68296.1 - 6.1e-14 51.1 0.3 2.2e-13 49.3 0.2 2.0 1 0 0 1 1 1 1 S4 domain Ribosomal_L21e PF01157.13 CCC68297.1 - 1.3e-45 153.2 5.9 1.8e-45 152.8 3.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.4 CCC68297.1 - 0.0022 17.3 0.0 0.0027 17.1 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Mito_carr PF00153.22 CCC68298.1 - 3.4e-78 257.4 3.2 2.4e-29 100.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Med8 PF10232.4 CCC68299.1 - 1.3e-47 162.2 5.8 1.3e-47 162.1 4.0 1.0 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 NPV_P10 PF05531.7 CCC68299.1 - 0.0019 18.3 1.2 0.11 12.7 0.0 2.6 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein DUF2421 PF10334.4 CCC68299.1 - 0.0059 16.2 0.1 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) NpwBP PF12622.2 CCC68300.1 - 3.6e-06 27.3 0.3 8.1e-06 26.2 0.2 1.6 1 0 0 1 1 1 1 mRNA biogenesis factor Tox-REase-9 PF15650.1 CCC68300.1 - 0.16 12.1 1.5 0.22 11.7 0.9 1.4 1 1 0 1 1 1 0 Restriction endonuclease fold toxin 9 WD40 PF00400.27 CCC68301.1 - 4.4e-21 73.9 13.3 5.1e-05 22.9 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCC68301.1 - 1.6e-16 59.9 0.7 2.8e-16 59.1 0.5 1.4 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 CCC68301.1 - 3.4e-08 33.4 0.7 2.1e-05 24.3 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PGI PF00342.14 CCC68302.1 - 8.3e-226 750.0 3.1 9.8e-226 749.8 2.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase SAP30_Sin3_bdg PF13867.1 CCC68302.1 - 0.041 13.7 0.6 17 5.4 0.2 3.1 3 0 0 3 3 3 0 Sin3 binding region of histone deacetylase complex subunit SAP30 WD40 PF00400.27 CCC68304.1 - 8.9e-62 202.9 18.9 7.9e-12 44.5 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 CCC68304.1 - 2.9e-49 166.8 0.7 5.3e-49 165.9 0.5 1.4 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 CCC68304.1 - 1.1e-06 28.2 0.1 3.1e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 LisH Nup160 PF11715.3 CCC68304.1 - 3.9e-05 22.0 2.1 0.19 9.8 0.1 3.7 2 2 0 3 3 3 2 Nucleoporin Nup120/160 SGT1 PF07093.6 CCC68304.1 - 0.00012 20.6 2.2 0.00018 20.0 1.5 1.1 1 0 0 1 1 1 1 SGT1 protein Peptidase_S30 PF01577.11 CCC68304.1 - 7.6 5.8 8.3 51 3.1 3.9 2.3 2 0 0 2 2 2 0 Potyvirus P1 protease Glyco_transf_15 PF01793.11 CCC68305.1 - 4.1e-120 400.7 12.9 4.1e-120 400.7 9.0 1.4 2 0 0 2 2 2 1 Glycolipid 2-alpha-mannosyltransferase zf-HYPF PF07503.7 CCC68305.1 - 0.64 9.4 4.7 3.6 7.0 1.2 2.4 2 0 0 2 2 2 0 HypF finger SH3_1 PF00018.23 CCC68306.1 - 1.6e-24 85.0 0.0 4.1e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 SH3 domain PX PF00787.19 CCC68306.1 - 6.7e-15 54.8 0.1 2.1e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 PX domain SH3_9 PF14604.1 CCC68306.1 - 3.8e-13 48.8 0.2 7.2e-10 38.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PB1 PF00564.19 CCC68306.1 - 2e-11 43.4 0.5 4e-11 42.4 0.3 1.5 1 0 0 1 1 1 1 PB1 domain SH3_2 PF07653.12 CCC68306.1 - 1.4e-08 34.0 0.1 1e-07 31.3 0.0 2.3 2 0 0 2 2 2 1 Variant SH3 domain DER1 PF04511.10 CCC68307.1 - 9.3e-35 119.9 15.5 1.1e-34 119.7 10.7 1.0 1 0 0 1 1 1 1 Der1-like family MCM PF00493.18 CCC68308.1 - 1e-133 445.2 0.1 6.4e-133 442.6 0.0 1.9 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 CCC68308.1 - 2.5e-26 92.5 1.8 6e-26 91.3 0.3 2.3 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCC68308.1 - 1.1e-07 31.2 0.1 1.6e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCC68308.1 - 1.8e-06 27.7 0.0 1.8e-05 24.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 CCC68308.1 - 0.00014 22.1 0.1 0.00058 20.2 0.0 2.1 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCC68308.1 - 0.03 13.8 0.0 0.71 9.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.6 CCC68308.1 - 0.065 12.8 0.0 0.24 11.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ECIST_Cterm PF14784.1 CCC68309.1 - 0.0074 16.2 0.1 0.03 14.2 0.0 2.1 1 0 0 1 1 1 1 C-terminal domain of the ECSIT protein F-box-like PF12937.2 CCC68309.1 - 0.012 15.3 0.0 0.027 14.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like Abhydrolase_6 PF12697.2 CCC68310.1 - 7.1e-24 84.9 0.0 9.3e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCC68310.1 - 1.9e-14 53.6 0.0 3.7e-14 52.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC68310.1 - 1.5e-13 50.8 0.0 2.9e-13 49.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 CCC68310.1 - 7.5e-08 32.1 0.0 2e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Ser_hydrolase PF06821.8 CCC68310.1 - 0.002 17.7 0.0 0.0044 16.6 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase PGAP1 PF07819.8 CCC68310.1 - 0.0051 16.4 0.0 0.03 13.9 0.0 2.2 2 1 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.3 CCC68310.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase FSH1 PF03959.8 CCC68310.1 - 0.03 13.7 0.0 0.18 11.1 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) LCAT PF02450.10 CCC68310.1 - 0.035 13.0 0.0 0.066 12.1 0.0 1.4 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF1749 PF08538.5 CCC68310.1 - 0.061 12.2 0.1 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Glyco_transf_15 PF01793.11 CCC68311.1 - 3.7e-135 450.1 11.3 4.9e-135 449.7 7.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Amidase PF01425.16 CCC68312.1 - 6.3e-93 312.0 0.0 8.6e-93 311.5 0.0 1.2 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 CCC68312.1 - 1.5e-80 270.4 0.0 2.3e-80 269.8 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 CCC68312.1 - 8.8e-63 211.3 0.1 1.7e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 CCC68312.1 - 2.9e-44 150.9 0.0 5.7e-44 150.0 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 CCC68312.1 - 1.5e-37 128.0 0.0 3.3e-37 126.9 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCC68312.1 - 2.9e-31 107.6 0.0 9.5e-31 105.9 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 CCC68312.1 - 5.2e-18 65.4 0.0 1.4e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 CCC68312.1 - 2e-15 56.2 0.5 1.3e-14 53.5 0.3 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 CCC68312.1 - 3.7e-13 49.3 0.0 8.2e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.6 CCC68312.1 - 7e-06 25.6 0.4 4.7e-05 22.9 0.0 2.5 2 1 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 CCC68312.1 - 7.6e-06 25.3 0.1 1.8e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 CCC68312.1 - 4.9e-05 23.2 0.0 8.7e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CCC68312.1 - 0.063 12.9 0.0 0.62 9.7 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like DUF3182 PF11379.3 CCC68312.1 - 0.33 9.6 0.0 0.58 8.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3182) Glutaredoxin PF00462.19 CCC68313.1 - 5.9e-17 61.3 0.0 1.7e-16 59.9 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin Exo5 PF09810.4 CCC68314.1 - 2e-29 102.8 0.0 8.7e-28 97.4 0.0 2.3 1 1 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease Cas_Cas4 PF01930.12 CCC68314.1 - 0.0084 16.0 0.2 4.2 7.2 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF83 PDDEXK_1 PF12705.2 CCC68314.1 - 0.014 14.7 0.7 0.16 11.3 0.5 2.5 1 1 0 1 1 1 0 PD-(D/E)XK nuclease superfamily RAMP4 PF06624.7 CCC68315.1 - 2e-07 30.4 0.0 2.4e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF2401 PF10287.4 CCC68316.1 - 6.3e-96 320.4 2.6 6.3e-96 320.4 1.8 2.6 3 0 0 3 3 3 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CCC68316.1 - 3.1e-29 100.9 3.7 3.3e-29 100.8 0.1 2.7 3 0 0 3 3 3 1 Glycine-rich protein domain (DUF2403) DUF515 PF04415.7 CCC68316.1 - 1 7.5 8.2 1.9 6.6 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Macoilin PF09726.4 CCC68316.1 - 5.9 5.0 9.5 8.6 4.5 6.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Gly_transf_sug PF04488.10 CCC68317.1 - 1.2e-22 80.2 0.1 3e-22 78.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 CCC68317.1 - 0.031 12.7 4.6 0.19 10.1 0.5 2.3 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain FtsX PF02687.16 CCC68317.1 - 0.17 11.6 0.2 0.17 11.6 0.2 1.7 2 0 0 2 2 2 0 FtsX-like permease family Dimer_Tnp_hAT PF05699.9 CCC68318.1 - 0.00029 20.4 0.1 0.0011 18.5 0.0 2.0 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region TFCD_C PF12612.3 CCC68318.1 - 0.02 14.2 1.7 2.2 7.6 0.0 2.8 3 0 0 3 3 3 0 Tubulin folding cofactor D C terminal Pkinase PF00069.20 CCC68319.1 - 4.3e-73 245.6 0.0 4.9e-73 245.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68319.1 - 4.2e-33 114.5 0.0 5.2e-33 114.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC68319.1 - 6.2e-06 25.3 0.0 1.2e-05 24.3 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCC68319.1 - 0.0033 17.2 0.1 0.049 13.3 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 CCC68319.1 - 0.026 13.5 0.3 0.09 11.8 0.1 1.9 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 CCC68319.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pox_ser-thr_kin PF05445.6 CCC68319.1 - 0.34 9.6 2.0 5.4 5.7 0.1 2.2 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase adh_short PF00106.20 CCC68320.1 - 3.6e-22 79.0 0.0 4.9e-22 78.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCC68320.1 - 5.2e-11 42.7 0.0 8.9e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCC68320.1 - 3.2e-07 30.1 0.0 4.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCC68320.1 - 0.003 17.5 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 CCC68320.1 - 0.0058 15.6 0.0 0.0083 15.1 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 CCC68320.1 - 0.03 13.2 0.1 0.049 12.5 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LRR_4 PF12799.2 CCC68321.1 - 0.0038 16.7 13.9 0.03 13.9 0.4 4.5 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCC68321.1 - 0.0057 16.5 5.4 4.3 7.7 0.6 4.5 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_6 PF13516.1 CCC68321.1 - 0.025 14.5 12.2 4.6 7.6 0.0 5.8 5 0 0 5 5 5 0 Leucine Rich repeat LRR_8 PF13855.1 CCC68321.1 - 1.5 8.6 12.7 1.5 8.6 0.8 4.1 3 2 2 5 5 5 0 Leucine rich repeat LRR_7 PF13504.1 CCC68321.1 - 9.3 6.9 12.1 2.9 8.4 0.2 5.0 5 1 0 5 5 5 0 Leucine rich repeat INCENP_ARK-bind PF03941.10 CCC68323.1 - 4.1e-19 68.1 0.3 1.1e-18 66.7 0.2 1.8 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region TPR_11 PF13414.1 CCC68324.1 - 4.8e-16 58.1 6.1 2.7e-13 49.3 0.9 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCC68324.1 - 1e-11 43.9 8.3 3.7e-05 23.1 0.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCC68324.1 - 1e-09 37.5 3.8 0.014 15.2 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCC68324.1 - 9.8e-05 22.2 0.7 0.12 12.2 0.3 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCC68324.1 - 0.00023 20.7 1.8 0.95 9.4 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3808 PF10300.4 CCC68324.1 - 0.00042 18.9 0.9 0.0006 18.4 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 CCC68324.1 - 0.00079 20.0 0.0 0.087 13.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCC68324.1 - 0.0015 18.5 2.3 0.0026 17.8 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCC68324.1 - 0.0021 18.3 0.1 0.056 13.7 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CCC68324.1 - 0.0032 17.5 4.3 0.0089 16.1 3.0 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 ThiS PF02597.15 CCC68324.1 - 0.076 13.4 0.6 3.6 8.0 0.0 2.6 2 0 0 2 2 2 0 ThiS family Glyco_transf_15 PF01793.11 CCC68325.1 - 1.9e-139 464.2 10.1 2.4e-139 463.9 7.0 1.2 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase cwf21 PF08312.7 CCC68326.1 - 1e-13 50.8 6.1 2.1e-13 49.8 4.3 1.5 1 0 0 1 1 1 1 cwf21 domain HD_4 PF13328.1 CCC68326.1 - 0.025 14.2 1.1 0.041 13.6 0.8 1.4 1 0 0 1 1 1 0 HD domain Mrr_N PF14338.1 CCC68326.1 - 0.027 14.5 0.4 0.062 13.3 0.2 1.6 1 1 0 1 1 1 0 Mrr N-terminal domain DUF258 PF03193.11 CCC68326.1 - 0.049 12.8 1.5 0.06 12.5 1.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 FKBP_N PF01346.13 CCC68326.1 - 0.81 9.7 4.8 0.18 11.8 0.9 1.7 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase PRP1_N PF06424.7 CCC68326.1 - 6.5 7.0 8.4 1.9 8.8 3.7 1.6 1 1 1 2 2 2 0 PRP1 splicing factor, N-terminal Alk_phosphatase PF00245.15 CCC68327.1 - 4.8e-121 404.3 0.0 5.8e-121 404.1 0.0 1.0 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 CCC68327.1 - 0.00014 21.3 0.1 0.00023 20.6 0.1 1.5 1 1 0 1 1 1 1 Metalloenzyme superfamily Peptidase_M10_C PF08548.6 CCC68327.1 - 0.044 13.3 0.1 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal Anp1 PF03452.9 CCC68328.1 - 6.3e-93 310.8 0.0 7.7e-93 310.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 CCC68328.1 - 0.023 14.3 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 2 Tox-REase-7 PF15649.1 CCC68328.1 - 0.044 13.9 0.2 0.083 13.0 0.1 1.4 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 7 DUF2905 PF11146.3 CCC68329.1 - 0.039 13.8 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) TRAP_alpha PF03896.11 CCC68329.1 - 1.5 7.7 5.5 2.5 7.0 3.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Catalase PF00199.14 CCC68330.1 - 4.9e-171 568.6 1.5 6.2e-171 568.2 1.0 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CCC68330.1 - 6.9e-13 48.2 0.4 7.1e-12 45.0 0.0 2.5 2 0 0 2 2 2 1 Catalase-related immune-responsive zf-RING_UBOX PF13445.1 CCC68331.1 - 4.2e-16 58.3 1.1 2.5e-15 55.9 0.8 2.5 1 0 0 1 1 1 1 RING-type zinc-finger CLTH PF10607.4 CCC68331.1 - 7.2e-12 45.2 1.2 7.2e-12 45.2 0.8 3.0 2 2 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_2 PF13639.1 CCC68331.1 - 0.022 14.5 2.3 0.028 14.2 0.3 2.2 2 0 0 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 CCC68331.1 - 0.086 12.5 0.7 0.34 10.6 0.5 2.0 1 0 0 1 1 1 0 zinc-RING finger domain zf-C2H2 PF00096.21 CCC68332.1 - 5.7e-08 32.6 5.4 0.00023 21.3 1.4 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC68332.1 - 1.1e-06 28.5 3.6 0.0049 17.1 0.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCC68332.1 - 0.024 14.8 5.0 0.34 11.2 0.8 2.7 2 1 0 2 2 2 0 Zinc-finger double domain zf-AN1 PF01428.11 CCC68332.1 - 0.08 12.8 1.1 12 5.8 0.1 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger zf-H2C2_5 PF13909.1 CCC68332.1 - 0.083 13.1 1.4 0.083 13.1 1.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain TFIIS_C PF01096.13 CCC68332.1 - 0.1 12.2 0.9 0.75 9.4 0.0 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) RRN7 PF11781.3 CCC68332.1 - 0.1 12.0 1.6 3.8 7.0 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 RIG-I_C-RD PF11648.3 CCC68332.1 - 0.12 12.2 0.4 0.22 11.4 0.2 1.4 1 0 0 1 1 1 0 C-terminal domain of RIG-I zf-C2H2_jaz PF12171.3 CCC68332.1 - 0.13 12.4 2.5 1.3 9.2 0.6 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NAC PF01849.13 CCC68333.1 - 4.3e-16 58.1 0.1 8.9e-16 57.1 0.0 1.6 1 0 0 1 1 1 1 NAC domain Ribosomal_60s PF00428.14 CCC68333.1 - 0.021 15.2 2.1 0.33 11.3 0.1 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein Glyco_hydro_20b PF02838.10 CCC68333.1 - 0.046 14.2 0.7 0.14 12.6 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase family 20, domain 2 DUF4657 PF15552.1 CCC68333.1 - 0.076 12.2 1.7 0.15 11.3 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4657) NOGCT PF08155.6 CCC68333.1 - 0.091 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NOGCT (NUC087) domain Bac_rhodopsin PF01036.13 CCC68334.1 - 1.8e-58 197.5 18.7 2e-58 197.3 12.9 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 CCC68334.1 - 0.53 9.6 10.9 0.45 9.8 2.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ApbA PF02558.11 CCC68335.1 - 0.00021 20.7 0.0 0.00055 19.3 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA IncA PF04156.9 CCC68335.1 - 1 8.9 25.1 0.37 10.3 8.6 2.8 3 0 0 3 3 3 0 IncA protein AAA_18 PF13238.1 CCC68336.1 - 3.6e-09 36.9 0.0 6.4e-09 36.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CCC68336.1 - 2.9e-07 30.2 0.0 3.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 CCC68336.1 - 3.2e-06 27.0 0.0 4.1e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCC68336.1 - 3.5e-06 27.8 0.0 4.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 CCC68336.1 - 4.9e-06 26.4 0.0 6.3e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase Zeta_toxin PF06414.7 CCC68336.1 - 0.00012 21.2 0.0 0.00018 20.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 CCC68336.1 - 0.00089 19.5 0.0 0.0016 18.7 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_19 PF13245.1 CCC68336.1 - 0.0019 17.9 0.0 0.0038 16.9 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain DUF258 PF03193.11 CCC68336.1 - 0.0021 17.2 0.0 0.012 14.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCC68336.1 - 0.0049 16.8 0.0 0.0063 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCC68336.1 - 0.0056 16.8 0.0 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 CCC68336.1 - 0.014 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain CPT PF07931.7 CCC68336.1 - 0.027 14.1 0.0 0.071 12.7 0.0 1.8 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein TrwB_AAD_bind PF10412.4 CCC68336.1 - 0.052 12.1 0.0 0.1 11.1 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.1 CCC68336.1 - 0.057 12.9 0.0 0.092 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 CCC68336.1 - 0.058 12.8 0.0 0.22 10.9 0.0 1.8 2 0 0 2 2 2 0 Guanylate kinase AAA_14 PF13173.1 CCC68336.1 - 0.065 13.1 0.0 0.18 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 CCC68336.1 - 0.066 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 Torsin T2SE PF00437.15 CCC68336.1 - 0.075 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF815 PF05673.8 CCC68336.1 - 0.081 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.24 CCC68336.1 - 0.082 13.1 0.0 0.16 12.1 0.0 1.5 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCC68336.1 - 0.084 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 CCC68336.1 - 0.099 11.4 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 CCC68336.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Pkinase PF00069.20 CCC68337.1 - 4.7e-46 157.0 6.6 1.8e-45 155.1 0.7 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68337.1 - 2.3e-22 79.3 0.1 5.2e-19 68.3 0.0 2.2 1 1 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCC68337.1 - 6.2e-06 25.3 0.0 9.4e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCC68337.1 - 0.0016 18.2 0.4 0.0033 17.1 0.3 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Clp1 PF06807.9 CCC68337.1 - 0.066 12.9 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA cleavage complex II protein Clp1 Kdo PF06293.9 CCC68337.1 - 0.068 12.2 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4296 PF14129.1 CCC68337.1 - 0.32 11.1 8.2 0.3 11.2 3.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4296) Sybindin PF04099.7 CCC68338.1 - 5.3e-35 120.2 2.9 1.2e-14 54.2 0.3 3.1 3 0 0 3 3 3 3 Sybindin-like family Sedlin_N PF04628.8 CCC68338.1 - 4.1e-08 33.1 0.4 1.5e-07 31.3 0.1 1.9 2 0 0 2 2 2 1 Sedlin, N-terminal conserved region Glyco_transf_34 PF05637.7 CCC68339.1 - 3.8e-73 245.9 1.4 4.1e-73 245.7 0.1 1.6 2 0 0 2 2 2 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 CCC68339.1 - 0.012 14.9 0.3 0.17 11.2 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function, DUF273 TPR_11 PF13414.1 CCC68340.1 - 8e-24 83.0 9.2 4.7e-13 48.5 0.2 4.3 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 CCC68340.1 - 2e-18 65.1 7.7 2.2e-06 27.0 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCC68340.1 - 1.2e-16 59.1 9.7 0.00012 21.7 0.0 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCC68340.1 - 2e-14 52.4 5.3 0.00054 19.9 0.0 4.8 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCC68340.1 - 5.2e-13 48.3 0.3 0.00094 19.6 0.1 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCC68340.1 - 1.4e-12 47.7 1.4 0.0038 17.5 0.0 4.4 2 2 2 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 CCC68340.1 - 8.9e-12 45.3 1.9 0.00027 21.5 0.1 4.2 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 CCC68340.1 - 2.7e-08 33.8 0.1 0.0028 17.7 0.0 4.2 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCC68340.1 - 2.6e-07 30.5 4.0 6.9e-05 22.7 0.0 4.1 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCC68340.1 - 9.5e-07 28.5 0.1 0.062 13.1 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCC68340.1 - 2.8e-05 23.5 8.4 0.027 14.2 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCC68340.1 - 3.8e-05 23.8 1.3 7.9 7.1 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCC68340.1 - 0.00022 20.7 0.1 0.84 9.5 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 CCC68340.1 - 0.00022 21.2 1.1 0.011 15.7 0.0 3.1 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 CCC68340.1 - 0.002 17.2 0.1 0.038 13.0 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat DEAD PF00270.24 CCC68341.1 - 6.5e-42 142.8 0.1 1.3e-38 132.1 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC68341.1 - 3.4e-27 94.1 0.1 1e-26 92.6 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC68341.1 - 0.00027 20.8 0.5 0.00098 18.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2404 PF10296.4 CCC68341.1 - 0.21 11.7 1.5 3.8 7.7 0.0 3.4 4 0 0 4 4 4 0 Putative integral membrane protein conserved region (DUF2404) DUF2986 PF11661.3 CCC68341.1 - 1.3 9.4 4.1 0.42 10.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2986) Amidase PF01425.16 CCC68342.1 - 1.9e-84 284.0 0.0 2.3e-84 283.8 0.0 1.1 1 0 0 1 1 1 1 Amidase MAM1 PF10434.4 CCC68342.1 - 0.0029 16.8 0.6 0.005 16.0 0.4 1.3 1 0 0 1 1 1 1 Monopolin complex protein MAM1 Ribosomal_L7Ae PF01248.21 CCC68343.1 - 2.5e-27 94.2 0.4 4.3e-27 93.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Abhydrolase_7 PF12715.2 CCC68343.1 - 0.073 11.9 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Abhydrolase family DUF3692 PF12469.3 CCC68343.1 - 0.13 12.4 1.6 0.47 10.6 1.1 1.9 1 1 0 1 1 1 0 CRISPR-associated protein Adaptin_N PF01602.15 CCC68346.1 - 2.5e-113 379.1 10.2 3.7e-113 378.6 7.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 CCC68346.1 - 1.5e-55 186.4 0.8 4.3e-55 184.9 0.0 2.2 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 CCC68346.1 - 2.1e-49 166.8 0.5 5.6e-49 165.4 0.3 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 CCC68346.1 - 1e-06 28.9 4.2 0.0003 21.0 0.0 3.8 2 1 1 4 4 4 1 HEAT repeats Cnd1 PF12717.2 CCC68346.1 - 5.5e-05 23.0 2.2 0.9 9.3 0.1 4.7 1 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CCC68346.1 - 0.0062 16.8 0.1 0.039 14.3 0.1 2.4 1 0 0 1 1 1 1 Vacuolar 14 Fab1-binding region Ribosomal_L5_C PF00673.16 CCC68347.1 - 6.8e-22 77.0 0.0 2.5e-21 75.2 0.0 1.9 2 0 0 2 2 2 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 CCC68347.1 - 1.1e-06 28.2 0.3 3.3e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 Flavokinase PF01687.12 CCC68348.1 - 1.4e-29 102.5 0.0 1.7e-29 102.2 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase GKAP PF03359.8 CCC68349.1 - 0.31 10.6 0.6 0.49 9.9 0.4 1.2 1 0 0 1 1 1 0 Guanylate-kinase-associated protein (GKAP) protein Aconitase PF00330.15 CCC68350.1 - 9.1e-71 238.7 0.5 5.6e-47 160.2 0.0 2.1 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCC68350.1 - 1.3e-29 102.9 0.6 6.3e-29 100.7 0.0 2.2 2 0 0 2 2 2 1 Aconitase C-terminal domain Reticulon PF02453.12 CCC68351.1 - 5e-37 127.0 3.3 7.7e-37 126.4 2.3 1.3 1 0 0 1 1 1 1 Reticulon Aminotran_1_2 PF00155.16 CCC68352.1 - 6e-72 242.5 0.0 6e-72 242.5 0.0 1.4 2 0 0 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 CCC68352.1 - 6.5e-09 34.5 0.0 1.1e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CCC68352.1 - 2.5e-06 26.5 0.0 1.7e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCC68352.1 - 0.00028 20.1 0.0 0.0007 18.8 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CCC68352.1 - 0.0017 17.4 1.2 0.11 11.5 0.0 2.3 2 0 0 2 2 2 2 DegT/DnrJ/EryC1/StrS aminotransferase family DUF3767 PF12597.3 CCC68353.1 - 5e-38 129.3 0.1 1e-37 128.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) YrhK PF14145.1 CCC68353.1 - 0.048 13.3 0.5 0.085 12.5 0.3 1.3 1 0 0 1 1 1 0 YrhK-like protein DUF3353 PF11833.3 CCC68353.1 - 2.6 7.4 5.3 1 8.7 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3353) CENP-T PF15511.1 CCC68354.1 - 1 8.5 23.3 2.2 7.4 16.1 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CFIA_Pcf11 PF11526.3 CCC68355.1 - 1.5e-23 82.7 12.9 8.8e-23 80.2 9.0 2.4 1 1 0 1 1 1 1 Subunit of cleavage factor IA Pcf11 VHS PF00790.14 CCC68355.1 - 0.00075 19.1 1.1 0.017 14.7 0.0 3.1 3 0 0 3 3 3 1 VHS domain DUF2314 PF10077.4 CCC68355.1 - 0.051 13.6 0.0 0.26 11.3 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2314) zf-H2C2_2 PF13465.1 CCC68355.1 - 0.091 13.0 1.3 10 6.6 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double domain COG2 PF06148.6 CCC68357.1 - 0.00085 19.1 6.1 0.0029 17.4 4.2 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 ADK PF00406.17 CCC68358.1 - 4.2e-61 205.2 0.0 5e-61 205.0 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CCC68358.1 - 5.3e-16 57.9 0.0 1.4e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CCC68358.1 - 1.3e-08 34.8 0.0 2.9e-08 33.6 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCC68358.1 - 8.6e-06 26.5 0.0 1.4e-05 25.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCC68358.1 - 0.00026 21.2 0.0 0.00046 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCC68358.1 - 0.0037 16.3 0.0 0.0071 15.4 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.12 CCC68358.1 - 0.063 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA PF00004.24 CCC68358.1 - 0.14 12.3 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Histone PF00125.19 CCC68359.1 - 6.5e-26 90.2 0.0 8.8e-26 89.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCC68359.1 - 9.8e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCC68360.1 - 1.4e-21 76.3 0.3 1.9e-21 75.9 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCC68360.1 - 6e-06 26.2 0.1 1.3e-05 25.0 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 CCC68360.1 - 0.0013 19.0 0.0 0.0022 18.2 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A HC2 PF07382.6 CCC68360.1 - 7.2 6.4 14.7 12 5.6 10.2 1.7 1 1 0 1 1 1 0 Histone H1-like nucleoprotein HC2 VIT1 PF01988.14 CCC68361.1 - 8.7e-57 192.0 0.4 1.2e-56 191.5 0.3 1.2 1 0 0 1 1 1 1 VIT family CRF1 PF10380.4 CCC68362.1 - 1.1e-15 58.0 1.8 4.4e-15 56.0 1.3 1.9 1 1 0 1 1 1 1 Transcription factor CRF1 Svf1 PF08622.5 CCC68363.1 - 1.2e-90 303.8 2.1 1.4e-90 303.5 1.5 1.1 1 0 0 1 1 1 1 Svf1-like PRKCSH-like PF12999.2 CCC68364.1 - 3.2e-36 124.5 10.5 3.2e-36 124.5 7.3 2.7 2 1 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 CCC68364.1 - 3e-16 59.2 3.9 1.4e-15 57.0 1.7 2.8 1 1 1 2 2 2 1 Glucosidase II beta subunit-like protein F-box-like PF12937.2 CCC68365.1 - 0.0019 17.8 0.4 0.0054 16.4 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCC68365.1 - 0.007 15.9 1.1 0.019 14.6 0.1 2.1 2 0 0 2 2 2 1 F-box domain Septin PF00735.13 CCC68366.1 - 1.9e-66 223.9 4.3 2.5e-66 223.5 3.0 1.1 1 0 0 1 1 1 1 Septin Pox_A32 PF04665.7 CCC68366.1 - 0.00035 19.9 0.0 0.00077 18.8 0.0 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein G-alpha PF00503.15 CCC68366.1 - 0.00051 18.8 0.2 0.00051 18.8 0.1 1.6 2 0 0 2 2 2 1 G-protein alpha subunit ABC_tran PF00005.22 CCC68366.1 - 0.0014 18.9 0.4 0.0037 17.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 CCC68366.1 - 0.0036 16.8 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain T2SE PF00437.15 CCC68366.1 - 0.0054 15.6 0.0 0.0091 14.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CCC68366.1 - 0.0055 16.2 0.0 0.0089 15.5 0.0 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family NACHT PF05729.7 CCC68366.1 - 0.0067 16.0 0.0 0.014 15.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF258 PF03193.11 CCC68366.1 - 0.008 15.3 0.1 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCC68366.1 - 0.01 15.9 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCC68366.1 - 0.012 15.7 0.0 0.038 14.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 CCC68366.1 - 0.016 14.9 1.3 0.025 14.2 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase Bac_DnaA PF00308.13 CCC68366.1 - 0.018 14.7 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein Ras PF00071.17 CCC68366.1 - 0.021 14.2 0.0 0.04 13.2 0.0 1.5 1 0 0 1 1 1 0 Ras family Miro PF08477.8 CCC68366.1 - 0.022 15.2 0.0 0.072 13.5 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 CCC68366.1 - 0.024 14.5 2.1 0.032 14.1 0.3 2.1 2 1 1 3 3 3 0 50S ribosome-binding GTPase DBI_PRT PF02277.12 CCC68366.1 - 0.031 13.3 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Phosphoribosyltransferase AAA_16 PF13191.1 CCC68366.1 - 0.033 14.1 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 CCC68366.1 - 0.038 13.4 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.14 CCC68366.1 - 0.042 13.2 0.1 0.087 12.2 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CCC68366.1 - 0.043 13.5 0.1 0.33 10.6 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 CCC68366.1 - 0.064 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 CCC68366.1 - 0.079 12.6 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad9_Rad53_bind PF08605.5 CCC68367.1 - 1.1e-40 138.4 0.1 2.3e-40 137.3 0.0 1.6 1 0 0 1 1 1 1 Fungal Rad9-like Rad53-binding BRCT PF00533.21 CCC68367.1 - 2.8e-10 40.1 0.9 9.6e-10 38.4 0.1 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain zf-C2H2 PF00096.21 CCC68368.1 - 6e-11 42.0 6.7 8.5e-05 22.6 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC68368.1 - 4.2e-09 36.2 8.4 3.9e-07 30.0 1.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC68368.1 - 1.4e-08 34.5 7.1 0.00068 19.7 0.3 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CCC68368.1 - 0.00018 21.6 1.5 0.12 12.5 0.2 3.1 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CCC68368.1 - 0.2 11.6 2.9 9.7 6.2 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Aha1_N PF09229.6 CCC68369.1 - 1.4e-36 125.3 1.0 3.2e-36 124.1 0.2 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 CCC68369.1 - 8.3e-10 38.8 0.1 1.5e-09 38.0 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Pox_A12 PF04651.8 CCC68369.1 - 0.047 13.8 0.1 0.076 13.1 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Fungal_trans_2 PF11951.3 CCC68370.1 - 3e-12 45.8 0.2 3e-12 45.8 0.2 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC68370.1 - 8e-10 38.4 10.8 1.3e-09 37.8 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cpn60_TCP1 PF00118.19 CCC68371.1 - 2.6e-144 481.4 13.5 3e-144 481.2 9.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ras PF00071.17 CCC68372.1 - 4.6e-50 169.1 0.0 5.2e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC68372.1 - 9.9e-12 45.4 0.0 1.3e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC68372.1 - 1.3e-05 24.5 0.0 1.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Dimer_Tnp_hAT PF05699.9 CCC68373.1 - 7e-09 35.1 0.2 3e-08 33.1 0.1 2.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 CCC68373.1 - 0.023 14.4 0.6 0.052 13.3 0.4 1.7 1 0 0 1 1 1 0 BED zinc finger W2 PF02020.13 CCC68374.1 - 5.9e-15 54.9 6.0 5.9e-15 54.9 4.1 2.1 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 CCC68374.1 - 8.2e-12 44.0 16.9 0.00085 18.7 1.9 4.0 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 CCC68374.1 - 6.6e-10 38.6 0.0 1.5e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 CCC68374.1 - 0.005 16.9 0.0 0.01 15.9 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CCC68374.1 - 0.029 13.9 16.8 0.4 10.2 1.9 3.7 1 1 2 3 3 3 0 Hexapeptide repeat of succinyl-transferase CYSTM PF12734.2 CCC68375.1 - 2.9e-05 24.0 68.4 0.0064 16.5 28.7 4.9 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance Pro-rich PF15240.1 CCC68375.1 - 0.12 12.4 24.0 0.15 12.1 16.6 1.1 1 0 0 1 1 1 0 Proline-rich Ofd1_CTDD PF10637.4 CCC68375.1 - 0.23 10.5 1.4 0.26 10.3 1.0 1.2 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Extensin_2 PF04554.8 CCC68375.1 - 2.2 8.2 15.4 3.8 7.4 10.7 1.4 1 1 0 1 1 1 0 Extensin-like region PAT1 PF09770.4 CCC68375.1 - 2.9 6.0 19.5 3 5.9 13.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Bindin PF02084.10 CCC68375.1 - 7.6 6.5 9.1 8.2 6.3 6.3 1.1 1 0 0 1 1 1 0 Bindin PIP5K PF01504.13 CCC68376.1 - 4.2e-86 288.1 4.5 1.2e-85 286.6 3.1 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Zn_clus PF00172.13 CCC68377.1 - 1.8e-09 37.3 7.4 3.2e-09 36.5 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF106 PF01956.11 CCC68377.1 - 2.1 7.8 5.0 4.8 6.6 3.5 1.6 1 0 0 1 1 1 0 Integral membrane protein DUF106 EST1_DNA_bind PF10373.4 CCC68378.1 - 4.8e-41 140.8 6.7 1e-40 139.7 4.6 1.6 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CCC68378.1 - 6.4e-25 87.6 1.2 6.4e-25 87.6 0.9 2.6 3 0 0 3 3 3 1 Telomerase activating protein Est1 Nop14 PF04147.7 CCC68378.1 - 0.0054 14.7 0.3 0.012 13.6 0.2 1.5 1 0 0 1 1 1 1 Nop14-like family Cation_efflux PF01545.16 CCC68379.1 - 1.2e-54 185.3 10.9 1.2e-54 185.3 7.5 3.4 2 2 1 3 3 3 1 Cation efflux family CPSF73-100_C PF11718.3 CCC68379.1 - 0.73 9.1 7.8 0.44 9.8 2.1 2.3 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF4131 PF13567.1 CCC68379.1 - 6 6.2 7.4 2.8 7.2 0.6 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Coq4 PF05019.8 CCC68380.1 - 4.4e-93 310.2 0.0 5.6e-93 309.9 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Toprim_4 PF13662.1 CCC68380.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Toprim domain SMI1_KNR4 PF09346.5 CCC68380.1 - 0.13 12.2 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) Myc-LZ PF02344.10 CCC68380.1 - 0.16 11.5 2.4 0.68 9.5 1.6 2.1 1 0 0 1 1 1 0 Myc leucine zipper domain DASH_Spc19 PF08287.6 CCC68381.1 - 1.3e-37 128.7 13.2 1.5e-37 128.6 9.2 1.0 1 0 0 1 1 1 1 Spc19 TBCA PF02970.11 CCC68381.1 - 0.0037 17.3 9.5 0.31 11.1 2.6 2.8 2 1 1 3 3 3 2 Tubulin binding cofactor A RNA_pol_Rpb5_C PF01191.14 CCC68381.1 - 0.025 14.1 0.2 0.025 14.1 0.1 1.7 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain APG6 PF04111.7 CCC68381.1 - 0.08 11.9 12.0 0.12 11.3 8.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 UPF0231 PF06062.6 CCC68381.1 - 0.27 11.1 3.0 0.13 12.1 0.6 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0231) NPV_P10 PF05531.7 CCC68381.1 - 0.67 10.2 4.8 5.1 7.4 0.0 2.7 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Mnd1 PF03962.10 CCC68381.1 - 1.3 8.6 11.2 12 5.5 0.1 2.0 1 1 1 2 2 2 0 Mnd1 family DUF342 PF03961.8 CCC68381.1 - 1.4 7.2 7.9 0.69 8.2 3.8 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF4355 PF14265.1 CCC68381.1 - 1.6 8.6 7.3 0.85 9.5 3.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) Fib_alpha PF08702.5 CCC68381.1 - 2.1 8.4 10.9 7.6 6.6 4.1 2.1 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family FHA PF00498.21 CCC68382.1 - 5.3e-16 58.5 0.2 3.2e-15 55.9 0.2 2.2 2 0 0 2 2 2 1 FHA domain Phage_GPO PF05929.6 CCC68382.1 - 0.055 12.7 4.5 0.088 12.0 3.1 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2894 PF11445.3 CCC68382.1 - 0.31 11.2 6.5 0.71 10.1 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DUF3650 PF12368.3 CCC68382.1 - 0.41 10.1 1.8 0.79 9.2 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3650) IncA PF04156.9 CCC68382.1 - 1.8 8.1 19.2 0.39 10.2 6.0 2.4 1 1 1 2 2 2 0 IncA protein SET PF00856.23 CCC68383.1 - 0.00095 19.5 0.2 0.0039 17.5 0.2 2.0 1 1 1 2 2 2 1 SET domain ApbA_C PF08546.6 CCC68384.1 - 3.1e-12 46.5 0.0 8.5e-12 45.1 0.0 1.7 1 1 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal CoaE PF01121.15 CCC68385.1 - 8.8e-63 210.9 0.0 1.1e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_17 PF13207.1 CCC68385.1 - 3.9e-07 30.9 0.0 5.1e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCC68385.1 - 0.00021 21.2 0.1 0.0012 18.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCC68385.1 - 0.00024 21.4 0.1 0.0006 20.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 CCC68385.1 - 0.0047 16.8 0.0 0.22 11.4 0.0 2.2 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_28 PF13521.1 CCC68385.1 - 0.0066 16.4 0.1 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain SKI PF01202.17 CCC68385.1 - 0.016 15.0 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase DEAD PF00270.24 CCC68387.1 - 7.4e-38 129.6 0.2 1.9e-37 128.3 0.1 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC68387.1 - 3.1e-19 68.5 0.1 6.4e-19 67.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC68387.1 - 5.6e-05 23.0 0.1 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-CCCH PF00642.19 CCC68388.1 - 8.7e-08 31.6 3.8 1.5e-07 30.9 2.6 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nucleoporin_FG PF13634.1 CCC68388.1 - 0.068 13.4 173.9 4.5e+02 1.1 36.5 5.5 1 1 2 3 3 3 0 Nucleoporin FG repeat region zf-CCCH_2 PF14608.1 CCC68388.1 - 0.08 12.9 4.0 0.17 11.9 2.8 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type SIR2 PF02146.12 CCC68389.1 - 3.2e-30 105.1 0.0 4.7e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family BLOC1_2 PF10046.4 CCC68389.1 - 0.025 14.6 0.6 0.07 13.2 0.4 1.7 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 UCH PF00443.24 CCC68389.1 - 0.03 13.4 0.1 0.05 12.7 0.1 1.3 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Proteasom_PSMB PF10508.4 CCC68389.1 - 0.045 12.0 0.0 0.065 11.4 0.0 1.2 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Mak16 PF04874.9 CCC68390.1 - 2.9 8.0 20.1 0.26 11.3 7.0 3.1 3 0 0 3 3 3 0 Mak16 protein C-terminal region CENP-B_dimeris PF09026.5 CCC68390.1 - 4 7.7 13.5 9.7 6.4 9.4 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 CCC68390.1 - 6.1 7.2 10.0 31 4.9 7.0 2.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal HALZ PF02183.13 CCC68391.1 - 0.028 14.1 2.9 0.037 13.7 0.7 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF972 PF06156.8 CCC68391.1 - 0.033 14.5 2.8 0.12 12.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Phosducin PF02114.11 CCC68392.1 - 1.7e-07 30.2 0.1 1.8e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 CCC68392.1 - 2.7e-05 23.7 0.0 4.6e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AHSP PF09236.5 CCC68392.1 - 0.046 13.9 1.2 0.13 12.5 0.4 2.0 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein Metallophos PF00149.23 CCC68393.1 - 9.4e-14 51.2 2.3 1.5e-13 50.5 1.6 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF912 PF06024.7 CCC68393.1 - 0.021 14.8 0.1 3.1 7.8 0.0 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) SAS4 PF15460.1 CCC68394.1 - 3e-32 110.5 2.2 3e-32 110.5 1.5 2.8 3 0 0 3 3 3 1 Something about silencing, SAS, complex subunit 4 Nipped-B_C PF12830.2 CCC68395.1 - 4.5e-36 124.2 3.0 4.1e-35 121.1 1.0 3.0 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 CCC68395.1 - 3.3e-12 46.0 1.0 1.3e-11 44.1 0.3 2.5 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 CCC68395.1 - 0.066 13.5 0.1 2.4 8.5 0.0 3.0 2 0 0 2 2 2 0 HEAT repeats PXA PF02194.10 CCC68396.1 - 3.8e-14 52.6 4.9 1.1e-13 51.2 0.0 2.6 1 1 1 2 2 2 2 PXA domain DUF1371 PF07115.6 CCC68397.1 - 0.094 12.8 0.8 0.12 12.5 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1371) CybS PF05328.7 CCC68398.1 - 1.7e-43 147.4 0.0 2.2e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 CybS UQ_con PF00179.21 CCC68399.1 - 2.5e-43 146.8 0.0 3.2e-43 146.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 CCC68399.1 - 1.2e-27 95.2 1.1 2.1e-27 94.4 0.7 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UPF0054 PF02130.12 CCC68399.1 - 0.11 11.8 0.0 0.7 9.1 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 Ada3 PF10198.4 CCC68400.1 - 2.2e-45 153.6 3.2 2.2e-45 153.6 2.2 2.7 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 MRP-S28 PF10213.4 CCC68402.1 - 5.7e-46 155.7 3.8 5.7e-46 155.7 2.6 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein HMG_box PF00505.14 CCC68403.1 - 1.1e-10 41.5 3.2 1.1e-10 41.5 2.2 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCC68403.1 - 1.4e-08 34.9 1.7 1.4e-08 34.9 1.2 2.1 2 0 0 2 2 2 1 HMG-box domain DUF3086 PF11285.3 CCC68403.1 - 0.0063 15.3 0.2 0.013 14.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) PsiA PF06952.6 CCC68403.1 - 0.007 15.4 2.0 0.007 15.4 1.4 1.8 2 1 0 2 2 2 1 PsiA protein ERAP1_C PF11838.3 CCC68403.1 - 0.012 14.8 0.1 0.022 14.0 0.1 1.3 1 0 0 1 1 1 0 ERAP1-like C-terminal domain IPK PF03770.11 CCC68404.1 - 3.2e-55 186.8 2.0 4.3e-55 186.4 1.0 1.5 2 0 0 2 2 2 1 Inositol polyphosphate kinase GTP_EFTU PF00009.22 CCC68405.1 - 7.3e-47 159.2 0.0 3.1e-46 157.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCC68405.1 - 4e-25 87.8 1.5 4e-25 87.8 1.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCC68405.1 - 3e-08 33.6 0.9 8.4e-08 32.2 0.6 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCC68405.1 - 0.00033 20.5 0.0 0.0014 18.5 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Med15 PF09606.5 CCC68405.1 - 1.5 6.9 61.8 1.9 6.5 42.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HSP20 PF00011.16 CCC68406.1 - 8.1e-09 35.2 0.0 8.1e-09 35.2 0.0 2.2 2 0 0 2 2 2 1 Hsp20/alpha crystallin family Bromo_MP PF01573.11 CCC68406.1 - 0.66 8.8 3.2 0.95 8.3 2.2 1.2 1 0 0 1 1 1 0 Bromovirus movement protein Sec7 PF01369.15 CCC68407.1 - 2.5e-67 226.2 0.1 8.7e-67 224.4 0.0 2.0 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 CCC68407.1 - 1.7e-52 177.2 0.7 1.7e-52 177.2 0.5 3.4 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 CCC68407.1 - 4.4e-29 99.8 1.9 2.4e-27 94.2 0.1 4.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) AMP-binding PF00501.23 CCC68408.1 - 1.4e-87 293.8 0.0 1.7e-87 293.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCC68408.1 - 3.1e-18 66.5 0.0 8e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mem_trans PF03547.13 CCC68409.1 - 1.3e-54 185.0 0.0 1.3e-53 181.7 0.0 2.0 1 1 0 1 1 1 1 Membrane transport protein Stm1_N PF09598.5 CCC68410.1 - 2.2e-17 63.4 5.4 2.2e-17 63.4 3.7 4.0 4 1 0 4 4 4 1 Stm1 DUF4604 PF15377.1 CCC68410.1 - 0.38 10.9 22.0 0.19 11.9 4.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) RCR PF12273.3 CCC68411.1 - 1.8e-09 38.2 0.0 2.9e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red Peptidase_C42 PF05533.7 CCC68411.1 - 0.074 12.8 0.1 3.1 7.7 0.0 2.2 1 1 1 2 2 2 0 Beet yellows virus-type papain-like endopeptidase C42 DUF3893 PF13032.1 CCC68412.1 - 0.061 13.4 0.4 0.14 12.2 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3893) Stb3 PF10330.4 CCC68413.1 - 4.8e-31 106.3 0.0 1.1e-30 105.1 0.0 1.6 1 0 0 1 1 1 1 Putative Sin3 binding protein Prothymosin PF03247.9 CCC68413.1 - 0.0059 16.7 15.3 0.0059 16.7 10.6 3.0 3 0 0 3 3 3 1 Prothymosin/parathymosin family Senescence_reg PF04520.8 CCC68413.1 - 0.65 10.4 17.8 0.18 12.3 9.8 2.0 2 0 0 2 2 2 0 Senescence regulator DUF4613 PF15390.1 CCC68413.1 - 1.3 7.1 15.5 2.3 6.3 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) CDC37_N PF03234.9 CCC68414.1 - 8.4e-66 221.6 15.1 8.4e-66 221.6 10.4 3.2 2 1 0 2 2 2 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 CCC68414.1 - 3e-46 157.0 7.8 3e-46 157.0 5.4 2.8 4 0 0 4 4 4 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 CCC68414.1 - 3.6e-21 74.8 4.5 3.6e-21 74.8 3.1 2.6 3 0 0 3 3 3 1 Cdc37 C terminal domain TFIID_30kDa PF03540.8 CCC68415.1 - 3.3e-26 90.8 0.1 5.9e-26 90.0 0.1 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit NapB PF03892.9 CCC68415.1 - 0.057 13.0 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) Sec5 PF15469.1 CCC68416.1 - 3e-49 167.2 10.1 3e-49 167.2 7.0 3.9 4 0 0 4 4 4 1 Exocyst complex component Sec5 Vps51 PF08700.6 CCC68416.1 - 0.0032 17.2 2.0 0.0032 17.2 1.4 3.0 3 0 0 3 3 3 1 Vps51/Vps67 WD40 PF00400.27 CCC68417.1 - 0.57 10.1 5.1 8.9 6.3 0.9 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Sec1 PF00995.18 CCC68418.1 - 9.8e-87 291.8 0.0 1.1e-86 291.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Cwf_Cwc_15 PF04889.7 CCC68419.1 - 3.4e-23 82.6 35.3 2.4e-13 50.3 19.5 2.3 1 1 1 2 2 2 2 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 CCC68419.1 - 0.01 13.8 14.9 0.011 13.6 10.3 1.2 1 0 0 1 1 1 0 Nop14-like family SGT1 PF07093.6 CCC68419.1 - 0.069 11.5 12.9 0.081 11.3 8.9 1.1 1 0 0 1 1 1 0 SGT1 protein PCRF PF03462.13 CCC68419.1 - 0.14 11.8 5.3 0.28 10.8 3.7 1.4 1 0 0 1 1 1 0 PCRF domain Daxx PF03344.10 CCC68419.1 - 0.18 10.2 17.2 0.2 10.0 12.0 1.0 1 0 0 1 1 1 0 Daxx Family NOA36 PF06524.7 CCC68419.1 - 1.7 7.7 7.2 2.9 7.0 5.0 1.4 1 0 0 1 1 1 0 NOA36 protein Spt5_N PF11942.3 CCC68419.1 - 2.4 8.8 21.8 9.5 6.9 15.1 2.0 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal DNA_pol_phi PF04931.8 CCC68419.1 - 7.1 4.2 17.5 10 3.7 12.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF506 PF04720.7 CCC68419.1 - 7.3 6.1 13.4 61 3.1 9.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF506) SH3_1 PF00018.23 CCC68420.1 - 4.6e-13 48.3 1.5 3.4e-12 45.5 0.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CCC68420.1 - 4.4e-11 42.1 0.4 1.2e-10 40.7 0.0 1.9 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CCC68420.1 - 8.9e-06 25.1 0.0 1.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TPR_19 PF14559.1 CCC68421.1 - 6.5e-06 26.3 0.3 0.05 13.9 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CCC68421.1 - 0.00014 21.9 0.3 0.28 11.3 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 CCC68421.1 - 0.00015 21.4 0.8 1.8 8.6 0.0 4.1 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCC68421.1 - 0.00027 20.5 0.3 0.17 11.5 0.0 3.0 3 1 0 3 3 3 2 TPR repeat TPR_14 PF13428.1 CCC68421.1 - 0.005 17.3 0.0 16 6.4 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCC68421.1 - 0.0092 15.7 0.1 18 5.4 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCC68421.1 - 0.0096 16.0 0.0 1.7 9.0 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCC68421.1 - 0.012 16.3 0.0 1.9 9.2 0.0 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCC68421.1 - 0.016 15.1 0.1 11 6.0 0.0 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 CCC68421.1 - 0.02 14.4 0.0 9.3 6.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 CCC68421.1 - 0.031 13.3 0.1 0.16 11.0 0.0 2.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCC68421.1 - 0.047 13.4 0.2 3.8 7.4 0.0 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TBPIP PF07106.8 CCC68421.1 - 0.33 10.4 0.1 0.33 10.4 0.0 2.2 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) AA_permease PF00324.16 CCC68422.1 - 7.4e-73 245.4 40.3 1.1e-72 244.9 27.9 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC68422.1 - 7e-33 113.7 46.2 1.7e-32 112.5 32.0 1.5 1 1 0 1 1 1 1 Amino acid permease SAC3_GANP PF03399.11 CCC68423.1 - 4.2e-56 189.7 0.4 4.2e-56 189.7 0.3 2.4 3 0 0 3 3 3 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family SAC3 PF12209.3 CCC68423.1 - 6.3e-13 48.6 0.6 6.3e-13 48.6 0.4 2.8 2 0 0 2 2 2 1 Leucine permease transcriptional regulator helical domain Semialdhyde_dhC PF02774.13 CCC68424.1 - 1.3e-44 152.3 0.0 1.9e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 CCC68424.1 - 1.7e-30 105.7 0.0 3.2e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 CCC68424.1 - 0.04 14.4 0.0 0.099 13.1 0.0 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Saccharop_dh PF03435.13 CCC68424.1 - 0.094 11.6 0.2 0.16 10.9 0.0 1.5 2 0 0 2 2 2 0 Saccharopine dehydrogenase DapB_N PF01113.15 CCC68424.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 CCC68424.1 - 0.12 12.3 0.8 0.33 10.9 0.0 2.1 2 0 0 2 2 2 0 NADH(P)-binding RNA_polI_A14 PF08203.6 CCC68425.1 - 5.7e-24 84.1 0.8 8.8e-24 83.5 0.0 1.7 2 0 0 2 2 2 1 Yeast RNA polymerase I subunit RPA14 MTBP_C PF14920.1 CCC68425.1 - 0.0095 15.4 0.2 0.013 15.0 0.2 1.2 1 0 0 1 1 1 1 MDM2-binding Pro_isomerase PF00160.16 CCC68426.1 - 9.2e-47 159.1 0.0 1e-46 158.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 CCC68426.1 - 0.036 13.8 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin domain RCR PF12273.3 CCC68427.1 - 0.00011 22.7 1.2 0.00011 22.7 0.9 2.0 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red F-box-like PF12937.2 CCC68428.1 - 1.9e-05 24.2 0.0 4.6e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCC68428.1 - 0.00086 18.9 0.0 0.0025 17.4 0.0 1.8 1 0 0 1 1 1 1 F-box domain BTB_2 PF02214.17 CCC68429.1 - 1.8e-07 31.2 0.6 0.0028 17.8 0.1 3.2 2 2 0 2 2 2 2 BTB/POZ domain Flocculin_t3 PF13928.1 CCC68430.1 - 2.8e-09 36.9 19.6 2.8e-09 36.9 13.6 4.3 1 1 2 3 3 3 1 Flocculin type 3 repeat ABC_membrane PF00664.18 CCC68431.1 - 4.2e-92 308.4 36.3 6.9e-55 186.3 6.5 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCC68431.1 - 2.8e-50 170.1 0.3 4.4e-31 107.9 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCC68431.1 - 5.6e-09 35.5 8.6 0.002 17.3 1.0 4.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCC68431.1 - 1e-08 35.3 0.0 0.0027 17.7 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 CCC68431.1 - 4.7e-07 29.4 0.1 0.033 13.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CCC68431.1 - 4.7e-06 27.0 0.6 0.0027 18.0 0.0 2.9 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.1 CCC68431.1 - 1.6e-05 24.3 0.6 0.12 11.9 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CCC68431.1 - 1.7e-05 24.9 2.3 0.72 9.7 0.3 4.7 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CCC68431.1 - 4.5e-05 23.3 0.1 0.14 12.1 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 CCC68431.1 - 0.00026 21.4 0.3 0.78 10.2 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 CCC68431.1 - 0.00038 19.6 0.1 0.43 9.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 CCC68431.1 - 0.0018 17.2 0.6 0.2 10.5 0.0 3.1 3 0 0 3 3 3 1 Type II/IV secretion system protein DUF87 PF01935.12 CCC68431.1 - 0.0046 16.8 2.8 0.27 11.0 0.1 3.0 2 0 0 2 2 2 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 CCC68431.1 - 0.0062 16.0 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AIG1 PF04548.11 CCC68431.1 - 0.011 14.8 2.1 0.13 11.3 0.0 3.0 3 0 0 3 3 3 0 AIG1 family Arch_ATPase PF01637.13 CCC68431.1 - 0.014 15.1 0.5 0.09 12.4 0.0 2.6 3 0 0 3 3 3 0 Archaeal ATPase AAA_10 PF12846.2 CCC68431.1 - 0.016 14.6 5.2 4.8 6.5 0.1 3.4 2 1 0 3 3 3 0 AAA-like domain HK PF02110.10 CCC68431.1 - 0.02 14.1 0.9 0.96 8.5 0.0 2.4 2 0 0 2 2 2 0 Hydroxyethylthiazole kinase family TrwB_AAD_bind PF10412.4 CCC68431.1 - 0.027 13.1 0.7 2.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Root_cap PF06830.6 CCC68431.1 - 0.054 13.3 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Root cap ArgK PF03308.11 CCC68431.1 - 0.063 12.0 0.0 5.1 5.7 0.0 2.3 2 0 0 2 2 2 0 ArgK protein Zeta_toxin PF06414.7 CCC68431.1 - 0.072 12.1 0.2 12 4.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Sigma54_activat PF00158.21 CCC68431.1 - 0.072 12.5 0.0 7.1 6.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_17 PF13207.1 CCC68431.1 - 0.081 13.7 0.1 8.4 7.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 CCC68431.1 - 0.083 13.1 0.1 4.7 7.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3007 PF11460.3 CCC68431.1 - 0.12 12.4 2.2 0.33 11.0 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) MobB PF03205.9 CCC68431.1 - 0.19 11.3 3.4 8.6 6.0 0.1 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 CCC68431.1 - 0.22 11.0 0.9 18 4.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 CCC68431.1 - 0.35 10.5 3.1 3.7 7.1 0.0 3.2 3 0 0 3 3 3 0 NACHT domain Dynamin_N PF00350.18 CCC68431.1 - 0.36 10.6 4.4 1.4 8.6 0.0 3.0 3 0 0 3 3 3 0 Dynamin family Rgp1 PF08737.5 CCC68433.1 - 4.2e-86 289.6 14.8 4.2e-86 289.6 10.3 1.6 2 0 0 2 2 2 1 Rgp1 efThoc1 PF11957.3 CCC68434.1 - 2.1e-80 270.6 31.2 2.9e-80 270.1 21.6 1.1 1 0 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Methyltransf_26 PF13659.1 CCC68437.1 - 5.4e-15 55.4 0.0 7.5e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCC68437.1 - 3.6e-11 42.7 0.0 4.5e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CCC68437.1 - 6.1e-07 29.1 0.0 8.9e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCC68437.1 - 0.0004 19.6 0.0 0.0008 18.6 0.0 1.4 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Met_10 PF02475.11 CCC68437.1 - 0.02 14.4 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.13 CCC68437.1 - 0.043 13.4 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 CCC68437.1 - 0.098 13.0 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Dopey_N PF04118.9 CCC68438.1 - 3.9e-114 380.5 1.6 3.9e-114 380.5 1.1 3.2 3 0 0 3 3 3 1 Dopey, N-terminal WD40 PF00400.27 CCC68439.1 - 2.7e-26 90.4 16.5 6.3e-06 25.8 0.1 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat Asp PF00026.18 CCC68440.1 - 1.6e-69 234.5 10.5 4e-69 233.2 7.3 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCC68440.1 - 2.9e-05 24.0 1.5 0.12 12.3 0.0 2.7 2 0 0 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCC68440.1 - 0.0004 20.8 1.0 8 7.0 0.0 3.8 3 0 0 3 3 3 2 Aspartyl protease RVP PF00077.15 CCC68440.1 - 0.0065 16.3 0.0 5.1 7.0 0.0 2.8 2 0 0 2 2 2 2 Retroviral aspartyl protease TAXi_C PF14541.1 CCC68440.1 - 0.023 14.2 0.1 0.38 10.2 0.1 2.3 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal TFIID_20kDa PF03847.8 CCC68441.1 - 7.9e-32 109.3 0.5 7.9e-32 109.3 0.4 2.3 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 CCC68441.1 - 0.00064 19.8 0.0 0.0016 18.4 0.0 1.7 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCC68441.1 - 0.017 15.1 0.0 0.071 13.1 0.0 2.1 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone KfrA_N PF11740.3 CCC68441.1 - 3.9 7.9 0.0 3.9 7.9 0.0 3.7 4 0 0 4 4 4 0 Plasmid replication region DNA-binding N-term Zip PF02535.17 CCC68442.1 - 6.9e-64 215.8 2.5 7.8e-64 215.6 1.7 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter zf-DHHC PF01529.15 CCC68443.1 - 4.6e-31 107.5 17.9 4.6e-31 107.5 12.4 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase Colicin_V PF02674.11 CCC68443.1 - 0.47 10.2 6.7 0.51 10.1 0.3 2.3 2 0 0 2 2 2 0 Colicin V production protein zf-C2H2 PF00096.21 CCC68444.1 - 6.4e-10 38.7 14.7 0.0025 18.0 0.6 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC68444.1 - 5.4e-07 29.5 14.1 0.0012 18.9 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC68444.1 - 0.00074 19.6 12.2 0.45 10.9 0.5 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger CASP_C PF08172.7 CCC68444.1 - 0.0021 17.1 4.5 0.004 16.2 3.1 1.5 1 0 0 1 1 1 1 CASP C terminal zf-C2H2_6 PF13912.1 CCC68444.1 - 0.013 15.4 0.5 0.61 10.0 0.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Bunya_G2 PF03563.8 CCC68444.1 - 0.026 13.4 0.5 0.043 12.7 0.3 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 AAA_23 PF13476.1 CCC68444.1 - 0.17 12.1 9.2 0.36 11.1 6.4 1.4 1 0 0 1 1 1 0 AAA domain AT_hook PF02178.14 CCC68444.1 - 0.19 11.5 5.7 0.49 10.2 3.9 1.8 1 0 0 1 1 1 0 AT hook motif DUF641 PF04859.7 CCC68444.1 - 0.2 11.3 7.4 0.44 10.3 5.1 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) zf-C2H2_jaz PF12171.3 CCC68444.1 - 0.23 11.6 7.2 25 5.1 0.2 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding Choline_kinase PF01633.15 CCC68445.1 - 7.3e-49 166.1 3.8 1.1e-48 165.6 2.6 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CCC68445.1 - 0.00072 19.3 0.0 0.0066 16.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family 2-oxoacid_dh PF00198.18 CCC68446.1 - 4.2e-81 271.5 0.0 6.2e-81 271.0 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCC68446.1 - 1.3e-16 60.0 0.8 2.3e-16 59.1 0.6 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.1 CCC68446.1 - 0.00055 20.2 0.2 0.0015 18.8 0.1 1.8 1 1 0 1 1 1 1 HlyD family secretion protein GCV_H PF01597.14 CCC68446.1 - 0.00075 19.1 0.1 0.0019 17.8 0.1 1.7 1 1 0 1 1 1 1 Glycine cleavage H-protein HlyD_2 PF12700.2 CCC68446.1 - 0.0011 18.2 0.1 0.002 17.3 0.0 1.5 1 1 0 1 1 1 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 CCC68446.1 - 0.0015 18.1 0.2 0.032 13.9 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD PF00529.15 CCC68446.1 - 0.0029 16.9 0.6 0.015 14.6 0.2 2.1 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.1 CCC68446.1 - 0.0073 16.0 0.2 0.027 14.2 0.0 2.1 2 1 0 2 2 2 1 RnfC Barrel sandwich hybrid domain DUF2360 PF10152.4 CCC68446.1 - 0.28 11.4 6.4 0.59 10.4 4.4 1.5 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Mcp5_PH PF12814.2 CCC68447.1 - 5.2e-39 132.9 0.0 5.2e-39 132.9 0.0 3.3 3 0 0 3 3 3 1 Meiotic cell cortex C-terminal pleckstrin homology zf-CCCH PF00642.19 CCC68448.1 - 5.2e-17 61.0 18.8 1.3e-09 37.5 3.1 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) BAF1_ABF1 PF04684.8 CCC68448.1 - 0.0041 16.0 9.9 0.0041 16.0 6.9 1.5 2 0 0 2 2 2 1 BAF1 / ABF1 chromatin reorganising factor zf-CCCH_2 PF14608.1 CCC68448.1 - 0.039 13.9 3.0 0.039 13.9 2.1 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Zip PF02535.17 CCC68448.1 - 0.039 12.9 3.0 0.043 12.8 2.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2946 PF11162.3 CCC68448.1 - 0.93 9.7 4.3 2 8.6 3.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) DUF2407_C PF13373.1 CCC68448.1 - 5.2 6.9 6.4 0.61 10.0 0.3 2.2 2 1 0 2 2 2 0 DUF2407 C-terminal domain RWD PF05773.17 CCC68449.1 - 2.4e-21 75.7 5.9 1.8e-20 72.8 4.1 2.2 1 1 0 1 1 1 1 RWD domain DUF4390 PF14334.1 CCC68449.1 - 0.0033 16.6 0.0 0.0076 15.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4390) UEV PF05743.8 CCC68449.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 UEV domain ENTH PF01417.15 CCC68450.1 - 2.7e-31 108.0 0.7 1.2e-30 105.8 0.0 2.3 2 0 0 2 2 2 1 ENTH domain ApoO PF09769.4 CCC68450.1 - 0.013 15.1 1.8 0.021 14.5 0.2 2.1 2 0 0 2 2 2 0 Apolipoprotein O DUF1189 PF06691.6 CCC68450.1 - 0.053 12.8 0.1 0.086 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) CDK5_activator PF03261.10 CCC68450.1 - 1.6 7.9 6.9 3.1 7.0 4.8 1.5 1 1 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein HSBP1 PF06825.7 CCC68451.1 - 0.0018 17.8 0.9 0.0036 16.8 0.6 1.5 1 0 0 1 1 1 1 Heat shock factor binding protein 1 WD40_alt PF14077.1 CCC68451.1 - 0.01 15.4 0.2 0.44 10.2 0.0 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif HLH PF00010.21 CCC68451.1 - 0.012 15.2 0.5 0.035 13.7 0.3 1.8 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain UPF0184 PF03670.8 CCC68451.1 - 0.1 12.7 1.7 0.18 11.9 0.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) Snapin_Pallidin PF14712.1 CCC68451.1 - 0.29 11.4 0.3 0.29 11.4 0.2 2.3 3 0 0 3 3 3 0 Snapin/Pallidin WD40 PF00400.27 CCC68453.1 - 9.8e-15 53.8 25.2 1.8e-07 30.7 0.3 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat zf-rbx1 PF12678.2 CCC68453.1 - 0.0077 16.3 6.6 0.02 14.9 4.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger RWD PF05773.17 CCC68453.1 - 0.01 15.7 0.0 0.037 13.9 0.0 1.9 1 0 0 1 1 1 0 RWD domain zf-RING_2 PF13639.1 CCC68453.1 - 0.018 14.8 8.9 0.043 13.6 6.2 1.6 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 CCC68453.1 - 0.12 12.4 11.3 0.27 11.3 7.8 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) C1_3 PF07649.7 CCC68453.1 - 0.15 12.1 5.6 0.32 11.0 3.9 1.6 1 0 0 1 1 1 0 C1-like domain EPSP_synthase PF00275.15 CCC68454.1 - 5e-139 463.3 0.1 7.3e-139 462.7 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CCC68454.1 - 4.7e-98 327.2 0.0 7.6e-98 326.5 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 CCC68454.1 - 1.9e-06 27.4 0.1 3.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Abhydrolase_6 PF12697.2 CCC68455.1 - 1.5e-18 67.4 0.0 2.5e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC68455.1 - 4.7e-13 49.2 0.0 2.4e-11 43.6 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCC68455.1 - 1e-09 38.3 0.0 4.7e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CCC68455.1 - 1.9e-07 30.4 1.5 9.4e-07 28.1 1.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 CCC68455.1 - 0.00025 20.5 0.0 0.0006 19.3 0.0 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_3 PF07859.8 CCC68455.1 - 0.0013 18.3 0.0 0.014 15.0 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CCC68455.1 - 0.002 17.7 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Esterase PF00756.15 CCC68455.1 - 0.0021 17.5 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.15 CCC68455.1 - 0.0035 17.5 0.0 0.016 15.4 0.0 1.9 2 0 0 2 2 2 1 Thioesterase domain Ser_hydrolase PF06821.8 CCC68455.1 - 0.0073 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.6 CCC68455.1 - 0.019 14.6 0.0 0.69 9.5 0.0 2.4 2 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Nucleopor_Nup85 PF07575.8 CCC68455.1 - 0.021 13.0 0.2 0.032 12.4 0.1 1.2 1 0 0 1 1 1 0 Nup85 Nucleoporin Ndr PF03096.9 CCC68455.1 - 0.042 12.3 0.0 0.14 10.6 0.0 1.9 2 0 0 2 2 2 0 Ndr family Chlorophyllase PF07224.6 CCC68455.1 - 0.05 12.3 0.0 0.083 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 CCC68455.1 - 0.096 11.5 0.0 0.26 10.1 0.0 1.7 2 0 0 2 2 2 0 Chlorophyllase enzyme DUF2841 PF11001.3 CCC68456.1 - 3.1e-35 120.7 1.8 3.1e-35 120.7 1.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2841) HLH PF00010.21 CCC68457.1 - 0.012 15.3 0.6 0.02 14.5 0.4 1.4 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Pkinase PF00069.20 CCC68458.1 - 1.7e-70 237.1 2.9 1.9e-69 233.6 2.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68458.1 - 2.3e-38 131.7 0.5 8.5e-37 126.6 0.4 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 CCC68458.1 - 1.1e-16 59.9 0.4 3.6e-16 58.3 0.0 2.0 2 0 0 2 2 2 1 Kinase associated domain 1 Kinase-like PF14531.1 CCC68458.1 - 2.2e-08 33.4 0.0 4.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCC68458.1 - 4.4e-06 25.9 0.1 1.1e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC68458.1 - 0.0062 16.2 0.1 0.024 14.3 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CCC68458.1 - 0.02 14.2 0.8 0.18 11.1 0.0 2.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL CBFD_NFYB_HMF PF00808.18 CCC68459.1 - 1.1e-05 25.4 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCC68459.1 - 0.0017 18.4 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Topo_Zn_Ribbon PF08272.6 CCC68459.1 - 0.041 13.2 0.1 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like DUF2052 PF09747.4 CCC68459.1 - 0.055 13.3 4.7 0.081 12.8 3.3 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TRM PF02005.11 CCC68460.1 - 4.9e-144 479.9 0.2 6.2e-144 479.5 0.1 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.11 CCC68460.1 - 0.00058 19.5 0.1 0.0025 17.4 0.0 2.1 2 0 0 2 2 2 1 Met-10+ like-protein CpXC PF14353.1 CCC68460.1 - 0.12 12.3 0.3 0.49 10.3 0.0 2.0 1 1 1 2 2 2 0 CpXC protein PrmA PF06325.8 CCC68460.1 - 0.13 11.3 0.5 0.22 10.6 0.4 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Apc4 PF12896.2 CCC68463.1 - 4.1e-19 68.7 4.6 4.1e-19 68.7 3.2 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 SUI1 PF01253.17 CCC68464.1 - 4.3e-15 55.2 0.0 1.4e-14 53.6 0.0 1.9 1 0 0 1 1 1 1 Translation initiation factor SUI1 SWIB PF02201.13 CCC68464.1 - 0.0011 18.6 0.1 0.0043 16.6 0.0 2.1 2 0 0 2 2 2 1 SWIB/MDM2 domain DUF506 PF04720.7 CCC68464.1 - 0.05 13.2 3.3 0.088 12.4 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Ribosomal_L1 PF00687.16 CCC68465.1 - 6.6e-23 81.2 0.1 8.6e-23 80.8 0.0 1.3 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Ribosomal_L34 PF00468.12 CCC68466.1 - 3.2e-16 58.7 4.3 3.2e-16 58.7 3.0 1.6 1 1 1 2 2 2 1 Ribosomal protein L34 Securin PF04856.8 CCC68467.1 - 7.7e-25 87.9 14.3 2.7e-13 50.1 1.2 2.1 2 0 0 2 2 2 2 Securin sister-chromatid separation inhibitor Aminotran_1_2 PF00155.16 CCC68468.1 - 4.8e-35 121.1 0.0 6.9e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCC68468.1 - 0.00036 19.7 0.0 0.00092 18.4 0.0 1.6 2 0 0 2 2 2 1 Beta-eliminating lyase Ribosomal_S13_N PF08069.7 CCC68468.1 - 0.025 14.4 0.2 0.073 12.9 0.1 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain TP53IP5 PF15331.1 CCC68469.1 - 0.54 10.1 4.7 1.1 9.1 2.7 1.9 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 Gaa1 PF04114.9 CCC68470.1 - 8.9e-126 420.5 12.9 1.7e-116 389.9 2.8 2.2 1 1 1 2 2 2 2 Gaa1-like, GPI transamidase component DUF3353 PF11833.3 CCC68470.1 - 3.4 7.0 7.5 4.1 6.8 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) FGGY_C PF02782.11 CCC68471.1 - 1.5e-45 155.2 0.0 2.3e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CCC68471.1 - 1.5e-22 80.1 0.1 2.1e-21 76.3 0.0 2.5 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Hexokinase_1 PF00349.16 CCC68471.1 - 0.00022 20.5 0.0 0.00039 19.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase UPF0075 PF03702.9 CCC68471.1 - 0.048 12.5 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) BcrAD_BadFG PF01869.15 CCC68471.1 - 0.077 12.2 0.8 2.2 7.5 0.2 2.3 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family TRAPPC-Trs85 PF12739.2 CCC68472.1 - 6.8e-97 324.7 1.7 8.9e-97 324.3 1.2 1.1 1 0 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit EMP70 PF02990.11 CCC68473.1 - 4.8e-189 629.1 15.0 4.8e-189 629.1 10.4 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 ERCC4 PF02732.10 CCC68473.1 - 0.013 15.2 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 ERCC4 domain Actin PF00022.14 CCC68474.1 - 2.5e-11 42.6 0.1 8.4e-09 34.3 0.0 2.2 1 1 0 2 2 2 2 Actin Y_phosphatase PF00102.22 CCC68474.1 - 0.15 11.3 0.2 0.22 10.8 0.1 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Serinc PF03348.10 CCC68475.1 - 2.7e-152 507.4 14.5 3.2e-152 507.1 10.0 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) PH_4 PF15404.1 CCC68476.1 - 4.4e-76 254.5 1.6 5.1e-76 254.3 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Spo7_2_N PF15407.1 CCC68476.1 - 1.8e-24 85.0 1.9 2e-24 84.8 0.1 2.2 2 0 0 2 2 2 1 Sporulation protein family 7 PH PF00169.24 CCC68476.1 - 0.0063 16.6 12.5 0.052 13.7 0.1 5.5 4 2 0 4 4 4 1 PH domain Ste5_C PF12194.3 CCC68477.1 - 2.6e-77 258.8 0.5 5.5e-77 257.7 0.3 1.5 1 0 0 1 1 1 1 Protein kinase Fus3-binding zf-RING_2 PF13639.1 CCC68477.1 - 2.5e-05 24.0 4.2 4.6e-05 23.1 2.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCC68477.1 - 0.23 11.4 2.7 0.34 10.9 1.3 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC68477.1 - 6.9 6.4 6.5 22 4.8 4.5 1.9 1 1 0 1 1 1 0 zinc-RING finger domain Peptidase_M24 PF00557.19 CCC68478.1 - 9e-08 31.9 0.1 4.1e-07 29.7 0.0 2.1 2 1 0 2 2 2 1 Metallopeptidase family M24 COPI_assoc PF08507.5 CCC68479.1 - 2e-28 98.8 3.9 2.1e-28 98.6 2.7 1.0 1 0 0 1 1 1 1 COPI associated protein 14-3-3 PF00244.15 CCC68480.1 - 6.2e-115 382.2 5.3 7.9e-115 381.8 3.7 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF885 PF05960.6 CCC68480.1 - 0.011 14.8 0.5 0.011 14.8 0.3 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) Glutaredoxin PF00462.19 CCC68481.1 - 1.5e-17 63.3 0.0 1.4e-16 60.2 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 CCC68481.1 - 3.5e-14 52.3 0.0 8.1e-14 51.1 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 CCC68481.1 - 5.8e-05 23.1 0.2 0.0085 16.1 0.0 2.6 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 CCC68481.1 - 0.00043 19.9 0.0 0.0029 17.2 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_2 PF13098.1 CCC68481.1 - 0.0076 16.4 0.2 0.45 10.7 0.0 2.7 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 CCC68481.1 - 0.057 13.4 0.0 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin-like ArsC PF03960.10 CCC68481.1 - 0.075 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 ArsC family MutS_V PF00488.16 CCC68482.1 - 1.8e-77 259.9 0.0 1.3e-76 257.1 0.0 2.0 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 CCC68482.1 - 4.8e-43 147.3 0.3 9.1e-43 146.4 0.2 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CCC68482.1 - 7.9e-33 112.8 0.1 2.6e-32 111.1 0.0 2.0 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 CCC68482.1 - 7.2e-14 51.7 0.9 2e-13 50.3 0.7 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 CCC68482.1 - 3.7e-12 46.4 0.0 1.3e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 MutS domain II AAA_29 PF13555.1 CCC68482.1 - 0.047 13.2 0.0 0.16 11.5 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain E1-E2_ATPase PF00122.15 CCC68484.1 - 3.6e-16 58.9 0.0 3.6e-16 58.9 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 CCC68484.1 - 9.8e-15 54.2 0.0 2.6e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCC68484.1 - 2.6e-13 50.5 0.0 7.1e-13 49.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC68484.1 - 1.1e-10 42.2 0.9 2e-08 34.9 0.7 3.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCC68484.1 - 0.0022 17.6 0.2 0.0053 16.3 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UQ_con PF00179.21 CCC68485.1 - 2.1e-46 156.8 0.0 2.4e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCC68485.1 - 0.00075 19.2 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 CCC68485.1 - 0.011 15.3 0.1 0.024 14.3 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 CCC68485.1 - 0.022 14.6 0.1 0.026 14.4 0.1 1.4 1 1 0 1 1 1 0 RWD domain zf-C2H2_jaz PF12171.3 CCC68486.1 - 9.5e-06 25.6 7.5 0.00052 20.0 0.5 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CCC68486.1 - 6.8e-05 22.9 14.6 0.0032 17.6 1.4 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCC68486.1 - 0.0021 18.2 14.5 0.014 15.6 2.0 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-Di19 PF05605.7 CCC68486.1 - 0.0034 17.4 6.3 0.0062 16.6 4.4 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 CCC68486.1 - 0.014 15.7 15.2 0.03 14.6 1.3 2.9 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.2 CCC68486.1 - 0.3 11.3 4.3 6.4 7.1 0.2 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCC68486.1 - 0.71 10.0 9.0 3.1 7.9 0.3 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) ABC_tran PF00005.22 CCC68487.1 - 1.2e-35 122.7 0.1 1.3e-16 61.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 CCC68487.1 - 1.8e-15 56.2 4.9 4.5e-15 54.9 3.4 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 CCC68487.1 - 9.4e-14 52.0 8.7 0.0039 17.1 1.4 4.3 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 CCC68487.1 - 1.9e-09 37.0 2.8 0.018 14.2 0.0 3.9 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 CCC68487.1 - 2.3e-07 30.1 2.8 0.11 11.4 0.0 4.3 4 1 1 5 5 5 2 AAA ATPase domain Fer4 PF00037.22 CCC68487.1 - 2.4e-07 30.0 3.8 2.4e-07 30.0 2.6 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.24 CCC68487.1 - 1.4e-05 25.2 0.1 0.074 13.2 0.0 2.7 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 CCC68487.1 - 1.9e-05 24.1 0.6 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CCC68487.1 - 2.8e-05 24.2 0.0 0.015 15.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCC68487.1 - 6.2e-05 22.2 4.3 0.048 12.8 0.0 3.0 3 0 0 3 3 2 2 Protein of unknown function, DUF258 Fer4_7 PF12838.2 CCC68487.1 - 0.00018 21.8 6.9 0.00019 21.7 0.2 2.6 2 0 0 2 2 2 1 4Fe-4S dicluster domain Miro PF08477.8 CCC68487.1 - 0.00018 21.9 0.0 0.35 11.3 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein NB-ARC PF00931.17 CCC68487.1 - 0.00029 19.7 0.0 0.078 11.8 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Fer4_6 PF12837.2 CCC68487.1 - 0.00038 20.2 3.3 0.00038 20.2 2.3 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_18 PF13238.1 CCC68487.1 - 0.00062 20.0 0.2 1.1 9.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 CCC68487.1 - 0.00071 19.6 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain Fer4_21 PF14697.1 CCC68487.1 - 0.0011 18.7 12.0 0.0023 17.7 8.3 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.6 CCC68487.1 - 0.0017 17.8 0.0 0.62 9.4 0.0 2.4 2 0 0 2 2 2 1 Virulence-associated protein E NACHT PF05729.7 CCC68487.1 - 0.0018 17.9 1.5 0.2 11.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain RNA_helicase PF00910.17 CCC68487.1 - 0.0018 18.4 0.1 0.5 10.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Fer4_2 PF12797.2 CCC68487.1 - 0.0026 17.5 2.4 0.0026 17.5 1.7 2.6 2 0 0 2 2 2 1 4Fe-4S binding domain SRP54 PF00448.17 CCC68487.1 - 0.0031 16.9 3.3 0.097 12.1 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_14 PF13173.1 CCC68487.1 - 0.0032 17.3 0.1 3.7 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 CCC68487.1 - 0.004 17.4 2.1 0.004 17.4 1.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain AAA_17 PF13207.1 CCC68487.1 - 0.0041 17.9 2.5 1.9 9.3 0.2 2.9 2 2 0 2 2 2 1 AAA domain MobB PF03205.9 CCC68487.1 - 0.0044 16.7 1.7 0.59 9.8 0.1 2.7 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 CCC68487.1 - 0.0054 16.1 0.1 2.7 7.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 CCC68487.1 - 0.0057 16.5 0.2 9.6 6.2 0.0 3.8 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Fer4_3 PF12798.2 CCC68487.1 - 0.0058 17.1 4.2 0.0058 17.1 2.9 2.4 2 0 0 2 2 1 1 4Fe-4S binding domain Rad17 PF03215.10 CCC68487.1 - 0.0059 15.3 0.0 1.1 7.9 0.0 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein Fer4_16 PF13484.1 CCC68487.1 - 0.0067 17.1 0.1 0.0067 17.1 0.1 2.6 2 1 1 3 3 1 1 4Fe-4S double cluster binding domain AAA_33 PF13671.1 CCC68487.1 - 0.0077 16.1 0.2 1.2 9.0 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CCC68487.1 - 0.0081 16.1 0.1 2.1 8.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain Fer4_10 PF13237.1 CCC68487.1 - 0.0098 15.6 1.5 0.0098 15.6 1.1 2.1 1 1 1 2 2 2 1 4Fe-4S dicluster domain AAA_30 PF13604.1 CCC68487.1 - 0.016 14.7 0.2 0.39 10.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CCC68487.1 - 0.021 14.5 1.5 0.14 11.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 CCC68487.1 - 0.027 14.0 0.2 0.72 9.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CCC68487.1 - 0.028 14.0 0.3 0.36 10.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 CCC68487.1 - 0.033 14.5 4.7 0.12 12.6 0.0 2.7 2 1 0 2 2 2 0 AAA domain Fer4_4 PF12800.2 CCC68487.1 - 0.042 14.2 2.2 0.042 14.2 1.5 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Septin PF00735.13 CCC68487.1 - 0.047 12.7 0.1 0.83 8.6 0.1 2.2 2 0 0 2 2 2 0 Septin PduV-EutP PF10662.4 CCC68487.1 - 0.08 12.4 2.1 0.13 11.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Fer4_17 PF13534.1 CCC68487.1 - 0.088 13.1 0.2 0.088 13.1 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S dicluster domain Thymidylate_kin PF02223.12 CCC68487.1 - 0.13 11.6 0.7 16 4.8 0.1 2.9 3 0 0 3 3 3 0 Thymidylate kinase Mg_chelatase PF01078.16 CCC68487.1 - 0.16 11.1 1.1 0.22 10.6 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI AAA_13 PF13166.1 CCC68487.1 - 0.16 10.4 0.0 0.16 10.4 0.0 2.2 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.8 CCC68487.1 - 0.16 10.8 0.1 6.3 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_19 PF13245.1 CCC68487.1 - 0.24 11.1 0.5 1.1 9.0 0.0 2.2 2 0 0 2 2 1 0 Part of AAA domain NTPase_1 PF03266.10 CCC68487.1 - 0.47 10.1 2.8 2.9 7.5 0.1 2.6 3 0 0 3 3 2 0 NTPase Fer4_8 PF13183.1 CCC68487.1 - 0.48 10.4 9.7 0.11 12.5 0.8 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain PQ-loop PF04193.9 CCC68488.1 - 7.7e-24 83.0 7.7 2.4e-19 68.6 1.2 2.6 2 0 0 2 2 2 2 PQ loop repeat SPW PF03779.9 CCC68488.1 - 0.0059 15.9 4.6 0.31 10.4 1.7 2.6 2 0 0 2 2 2 2 SPW repeat MMR_HSR1_C PF08438.5 CCC68488.1 - 0.055 13.7 0.1 0.093 12.9 0.1 1.3 1 0 0 1 1 1 0 GTPase of unknown function C-terminal DUF2104 PF09877.4 CCC68488.1 - 0.48 10.4 5.4 2.8 7.9 0.2 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2104) ABC2_membrane_5 PF13346.1 CCC68488.1 - 3.2 6.9 21.3 0.13 11.5 7.9 2.2 1 1 2 3 3 3 0 ABC-2 family transporter protein YfhO PF09586.5 CCC68488.1 - 5.9 4.7 7.3 4.2 5.2 0.4 2.0 2 0 0 2 2 2 0 Bacterial membrane protein YfhO GLYCAM-1 PF05242.6 CCC68489.1 - 0.012 15.5 1.0 0.045 13.6 0.7 1.9 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) WSK PF03832.8 CCC68489.1 - 0.78 9.1 3.6 1.5 8.2 2.5 1.4 1 0 0 1 1 1 0 WSK motif SPX PF03105.14 CCC68489.1 - 7 6.3 28.8 14 5.3 13.8 4.9 2 1 0 2 2 2 0 SPX domain Slu7 PF11708.3 CCC68490.1 - 2.3e-41 142.1 11.7 2.3e-41 142.1 8.1 1.9 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC PF00098.18 CCC68490.1 - 1.1e-05 25.1 1.5 1.7e-05 24.4 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CCC68490.1 - 0.0024 17.4 1.0 0.0068 16.0 0.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_6 PF15288.1 CCC68490.1 - 0.026 14.1 2.7 0.071 12.7 1.9 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF234 PF03008.9 CCC68490.1 - 0.044 13.9 1.1 0.11 12.6 0.8 1.7 1 0 0 1 1 1 0 Archaea bacterial proteins of unknown function Nop52 PF05997.7 CCC68491.1 - 5.9e-64 215.4 5.4 7e-64 215.2 3.7 1.0 1 0 0 1 1 1 1 Nucleolar protein,Nop52 HSNSD PF12062.3 CCC68491.1 - 0.1 10.9 1.1 0.13 10.6 0.1 1.6 2 0 0 2 2 2 0 heparan sulfate-N-deacetylase SecE PF00584.15 CCC68492.1 - 2.4e-10 39.8 0.0 2.6e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex ASFV_p27 PF06556.6 CCC68492.1 - 0.04 13.8 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 IAP-like protein p27 C-terminus Coiled-coil_56 PF09813.4 CCC68492.1 - 0.075 13.0 0.0 0.085 12.8 0.0 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 56 DUF846 PF05832.7 CCC68494.1 - 1.3e-46 157.8 4.6 1.6e-46 157.5 3.2 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Methyltransf_8 PF05148.10 CCC68495.1 - 5.5e-62 209.2 0.0 1.6e-61 207.7 0.0 1.7 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CCC68495.1 - 9.3e-09 35.6 0.2 8.1e-07 29.4 0.0 3.2 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC68495.1 - 0.00072 19.1 0.6 0.0077 15.8 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC68495.1 - 0.031 14.6 0.2 0.21 11.9 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 CCC68495.1 - 0.08 12.3 0.0 3 7.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.1 CCC68495.1 - 0.091 12.4 0.9 0.23 11.1 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Ndc1_Nup PF09531.5 CCC68495.1 - 7.6 4.8 6.1 11 4.3 4.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Stn1 PF10451.4 CCC68496.1 - 4.8e-51 173.0 0.4 7.5e-51 172.4 0.1 1.5 2 0 0 2 2 2 1 Telomere regulation protein Stn1 Stn1_C PF12659.2 CCC68496.1 - 9.6e-31 106.2 4.8 2.1e-30 105.1 3.3 1.6 1 0 0 1 1 1 1 Telomere capping C-terminal wHTH DDE_1 PF03184.14 CCC68497.1 - 2.8e-74 248.9 4.1 5.6e-74 247.9 2.9 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 CCC68497.1 - 8.6e-14 51.1 0.2 8.6e-14 51.1 0.1 2.6 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain HTH_32 PF13565.1 CCC68497.1 - 0.07 13.9 0.0 0.55 11.0 0.1 2.4 2 0 0 2 2 2 0 Homeodomain-like domain Clathrin PF00637.15 CCC68498.1 - 1.1e-22 80.1 0.2 1.1e-22 80.1 0.2 3.0 3 0 0 3 3 3 1 Region in Clathrin and VPS WD40 PF00400.27 CCC68498.1 - 5.2e-05 22.9 0.7 0.00049 19.8 0.5 2.4 2 0 0 2 2 2 1 WD domain, G-beta repeat CENP-B_dimeris PF09026.5 CCC68498.1 - 9.1 6.5 12.1 0.56 10.4 4.2 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Tbf5 PF06331.7 CCC68499.1 - 3.6e-30 103.5 0.2 4.1e-30 103.3 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 YokU PF14122.1 CCC68499.1 - 0.065 12.9 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 YokU-like protein DUF3738 PF12543.3 CCC68500.1 - 0.0036 16.8 0.1 0.0046 16.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3738) GvpL_GvpF PF06386.6 CCC68500.1 - 0.12 11.9 0.1 0.13 11.7 0.1 1.0 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Histone_HNS PF00816.16 CCC68500.1 - 0.13 12.7 2.1 0.18 12.3 1.4 1.2 1 0 0 1 1 1 0 H-NS histone family Cwf_Cwc_15 PF04889.7 CCC68500.1 - 0.28 10.8 4.8 0.36 10.5 3.3 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Methyltransf_23 PF13489.1 CCC68501.1 - 1.8e-21 76.5 0.0 2.7e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC68501.1 - 3e-15 56.1 0.0 4.5e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCC68501.1 - 5.4e-13 49.2 0.0 9.1e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC68501.1 - 2.1e-11 44.3 0.0 3.6e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCC68501.1 - 5.1e-11 42.9 0.0 1.6e-10 41.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCC68501.1 - 1.9e-07 30.4 0.0 2.8e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 CCC68501.1 - 1.3e-06 28.6 0.0 2.5e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 CCC68501.1 - 1.8e-05 24.0 0.0 2.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 CCC68501.1 - 2.2e-05 23.9 0.0 3.7e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 CCC68501.1 - 3e-05 23.4 0.0 6.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DREV PF05219.7 CCC68501.1 - 0.00019 20.4 0.0 0.0003 19.7 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_26 PF13659.1 CCC68501.1 - 0.00042 20.3 0.0 0.0011 18.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CCC68501.1 - 0.00097 18.5 0.0 0.0017 17.8 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 CCC68501.1 - 0.001 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCC68501.1 - 0.0024 16.6 0.0 0.0043 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CheR PF01739.13 CCC68501.1 - 0.0058 15.9 0.0 0.073 12.3 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain RrnaAD PF00398.15 CCC68501.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CCDC-167 PF15188.1 CCC68502.1 - 0.044 13.7 0.3 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SWIM PF04434.12 CCC68502.1 - 0.21 11.1 4.7 0.63 9.5 0.0 2.4 2 0 0 2 2 2 0 SWIM zinc finger KaiC PF06745.8 CCC68504.1 - 6.3e-07 28.7 0.0 1.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 KaiC Arch_ATPase PF01637.13 CCC68504.1 - 5.2e-05 23.0 0.2 0.00012 21.9 0.1 1.7 2 1 0 2 2 2 1 Archaeal ATPase Rad51 PF08423.6 CCC68504.1 - 0.0003 19.8 0.0 0.00055 18.9 0.0 1.4 1 0 0 1 1 1 1 Rad51 AAA_18 PF13238.1 CCC68504.1 - 0.0024 18.2 0.1 0.0059 16.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCC68504.1 - 0.005 16.2 0.0 0.034 13.5 0.0 2.3 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_17 PF13207.1 CCC68504.1 - 0.0075 17.0 0.2 0.018 15.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.10 CCC68504.1 - 0.009 14.9 0.0 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_24 PF13479.1 CCC68504.1 - 0.01 15.3 0.0 0.028 13.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 CCC68504.1 - 0.011 15.1 0.0 0.027 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCC68504.1 - 0.017 15.2 0.1 0.21 11.7 0.1 2.5 1 1 0 1 1 1 0 AAA domain Glyco_transf_20 PF00982.16 CCC68505.1 - 3.4e-149 497.3 0.5 1.3e-148 495.4 0.4 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 CCC68505.1 - 7e-82 273.8 0.0 1.2e-81 273.1 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase PAP2 PF01569.16 CCC68507.1 - 4.6e-09 36.0 6.0 4.6e-09 36.0 4.2 2.7 2 1 0 2 2 2 1 PAP2 superfamily Acetyltransf_7 PF13508.1 CCC68508.1 - 2.9e-09 36.9 0.0 4.1e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCC68508.1 - 5.3e-09 35.9 0.0 9.6e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CCC68508.1 - 3.2e-06 27.0 0.0 1.6e-05 24.7 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCC68508.1 - 0.00057 19.8 0.0 0.00096 19.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCC68508.1 - 0.036 13.9 0.0 0.47 10.4 0.0 2.2 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCC68508.1 - 0.046 13.8 0.0 0.069 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCC68508.1 - 0.047 13.4 0.0 0.078 12.7 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein PRP1_N PF06424.7 CCC68510.1 - 0.12 12.7 3.0 0.12 12.6 2.1 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF1851 PF08906.6 CCC68510.1 - 0.13 12.2 0.1 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1851) UCH PF00443.24 CCC68512.1 - 1.1e-67 228.0 0.8 1.1e-67 228.0 0.6 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC68512.1 - 1.4e-27 96.9 0.1 1.4e-27 96.9 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 CCC68512.1 - 9.2e-07 29.2 0.0 1.9e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Zn-ribbon_8 PF09723.5 CCC68512.1 - 0.053 13.4 1.4 1.1 9.3 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-MIZ PF02891.15 CCC68512.1 - 0.12 11.8 0.1 0.12 11.8 0.1 2.1 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger BSD PF03909.12 CCC68513.1 - 5.1e-15 54.9 0.0 1.3e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 BSD domain hDGE_amylase PF14701.1 CCC68513.1 - 4.3 6.1 10.8 0.091 11.6 2.5 1.7 2 0 0 2 2 2 0 glucanotransferase domain of human glycogen debranching enzyme Y_phosphatase2 PF03162.8 CCC68514.1 - 6.4e-56 188.2 1.5 9.5e-56 187.6 1.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 CCC68514.1 - 0.027 14.0 0.1 0.081 12.5 0.1 1.8 1 1 0 1 1 1 0 Dual specificity phosphatase, catalytic domain RPAP2_Rtr1 PF04181.8 CCC68515.1 - 3.5e-12 46.2 2.6 1.3e-11 44.4 1.8 2.0 1 1 0 1 1 1 1 Rtr1/RPAP2 family Ferritin PF00210.19 CCC68516.1 - 0.016 14.9 0.0 0.072 12.8 0.0 2.1 2 0 0 2 2 2 0 Ferritin-like domain Complex1_LYR PF05347.10 CCC68516.1 - 0.019 14.7 3.0 0.038 13.7 0.7 2.5 2 0 0 2 2 2 0 Complex 1 protein (LYR family) CENP-H PF05837.7 CCC68516.1 - 0.56 10.3 4.0 2.9 8.1 2.0 2.4 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Complex1_LYR_1 PF13232.1 CCC68516.1 - 1.6 8.9 6.1 0.45 10.7 0.5 2.7 2 1 0 2 2 2 0 Complex1_LYR-like Cofilin_ADF PF00241.15 CCC68517.1 - 1.3e-07 31.5 0.0 1.5e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Myb_Cef PF11831.3 CCC68517.1 - 0.13 11.4 0.2 0.21 10.7 0.2 1.4 1 0 0 1 1 1 0 pre-mRNA splicing factor component Aminotran_1_2 PF00155.16 CCC68518.1 - 4e-67 226.7 0.0 4.8e-67 226.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II ABC_tran PF00005.22 CCC68519.1 - 1.1e-23 84.0 0.0 6.9e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 CCC68519.1 - 1.4e-05 25.2 7.6 0.038 13.9 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCC68519.1 - 0.0015 18.0 0.0 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 CCC68519.1 - 0.0044 16.8 0.1 0.56 10.1 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 CCC68519.1 - 0.0086 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Miro PF08477.8 CCC68519.1 - 0.021 15.3 0.0 0.075 13.5 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 CCC68519.1 - 0.085 12.9 0.1 3.2 7.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 CCC68519.1 - 0.11 11.6 0.0 0.27 10.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 CCC68519.1 - 0.35 11.1 0.1 0.35 11.1 0.0 2.7 3 1 0 3 3 3 0 AAA domain zf-C2H2_jaz PF12171.3 CCC68520.1 - 1.2e-05 25.3 5.6 0.0019 18.2 0.2 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CCC68520.1 - 0.00079 19.5 5.5 0.0015 18.6 3.8 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_2 PF13465.1 CCC68520.1 - 0.0038 17.4 16.6 0.014 15.6 2.0 3.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC68520.1 - 0.0039 17.4 18.4 0.019 15.2 1.0 3.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CCC68520.1 - 0.66 10.1 7.5 8.5 6.5 0.1 2.7 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 CCC68520.1 - 1.4 9.3 18.5 0.52 10.7 1.0 3.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type Acid_PPase PF12689.2 CCC68521.1 - 3.4e-44 150.4 0.0 4.1e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase zf-UBR PF02207.15 CCC68522.1 - 4.9e-12 45.3 12.4 4.9e-12 45.3 8.6 2.6 3 0 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) UAF_Rrn10 PF05234.6 CCC68524.1 - 3.1e-45 153.0 0.1 3.8e-45 152.7 0.1 1.1 1 0 0 1 1 1 1 UAF complex subunit Rrn10 Cep57_MT_bd PF06657.8 CCC68525.1 - 0.006 16.4 0.3 0.08 12.8 0.1 2.2 2 0 0 2 2 2 1 Centrosome microtubule-binding domain of Cep57 zf-CCHC_4 PF14392.1 CCC68525.1 - 0.057 13.0 2.5 0.36 10.5 1.3 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 CCC68525.1 - 0.7 9.9 4.3 0.91 9.5 1.5 2.0 2 0 0 2 2 2 0 Zinc knuckle LSM PF01423.17 CCC68526.1 - 2.4e-16 59.0 0.3 3.3e-16 58.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain DUF4443 PF14544.1 CCC68527.1 - 3.5e-05 23.6 0.2 5.3e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4443) EMP24_GP25L PF01105.19 CCC68528.1 - 3.8e-41 140.8 0.1 4.4e-41 140.6 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD chaperone_DMP PF10448.4 CCC68528.1 - 0.012 15.4 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 20S proteasome chaperone zf-SNAP50_C PF12251.3 CCC68528.1 - 0.11 11.8 0.1 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal Metallophos PF00149.23 CCC68529.1 - 2.6e-44 151.0 0.1 3.1e-44 150.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_6 PF13964.1 CCC68530.1 - 8e-17 60.6 3.6 2e-07 30.9 0.0 5.5 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CCC68530.1 - 1.4e-14 53.5 0.2 0.00013 21.6 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CCC68530.1 - 2.2e-12 46.3 3.2 6.2e-05 22.4 0.0 3.6 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 CCC68530.1 - 1.8e-10 40.6 0.0 0.0035 17.4 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CCC68530.1 - 1.5e-08 34.0 0.2 0.0029 17.3 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.1 CCC68530.1 - 0.0011 18.8 0.0 0.058 13.3 0.0 3.3 3 0 0 3 3 3 1 Kelch motif BIR PF00653.16 CCC68530.1 - 0.084 13.3 0.3 0.25 11.8 0.2 1.8 1 0 0 1 1 1 0 Inhibitor of Apoptosis domain WD40 PF00400.27 CCC68531.1 - 6.9e-17 60.6 1.2 0.0012 18.6 0.1 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Ribosomal_S26e PF01283.14 CCC68532.1 - 2.5e-50 169.4 8.7 3e-50 169.2 6.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1101 PF06503.6 CCC68532.1 - 0.029 13.2 0.1 0.031 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) Pkinase PF00069.20 CCC68533.1 - 6.1e-75 251.7 0.1 7.6e-75 251.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68533.1 - 2.8e-50 170.7 0.0 3.6e-50 170.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC68533.1 - 6.4e-10 38.4 0.0 1e-08 34.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CCC68533.1 - 0.004 16.2 0.0 0.0079 15.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC68533.1 - 0.025 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CCC68533.1 - 0.11 11.8 0.6 0.4 9.9 0.0 2.1 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL Fungal_trans PF04082.13 CCC68534.1 - 1.2e-63 214.4 2.5 3.7e-63 212.8 1.8 1.9 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 CCC68534.1 - 9.6e-10 38.2 9.7 0.0002 21.4 2.5 3.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC68534.1 - 2e-08 33.9 9.3 0.0003 20.9 2.2 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCC68534.1 - 0.096 12.6 2.9 6.6 6.7 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger MRG PF05712.8 CCC68535.1 - 9.8e-50 168.1 3.2 9.8e-50 168.1 2.2 1.7 2 0 0 2 2 2 1 MRG Tudor-knot PF11717.3 CCC68535.1 - 4.9e-07 29.3 0.1 4e-06 26.4 0.0 2.4 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain CMV_1a PF12467.3 CCC68535.1 - 0.0069 16.7 5.3 0.017 15.5 3.7 1.6 1 0 0 1 1 1 1 Cucumber mosaic virus 1a protein family Bap31 PF05529.7 CCC68535.1 - 0.076 12.4 3.7 1.7 8.0 0.5 2.5 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Neur_chan_memb PF02932.11 CCC68535.1 - 0.77 9.5 5.0 1.2 8.9 3.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.20 CCC68536.1 - 4.7e-31 107.8 0.0 8.1e-31 107.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68536.1 - 1.8e-11 43.6 0.0 2.6e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Imm15 PF15590.1 CCC68536.1 - 0.0059 15.6 1.3 0.015 14.3 0.1 2.4 3 0 0 3 3 3 1 Immunity protein 15 APH PF01636.18 CCC68536.1 - 0.16 11.7 0.0 2.5 7.7 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family HECT PF00632.20 CCC68538.1 - 5.5e-90 301.7 0.0 7.8e-90 301.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 CCC68538.1 - 5.5e-34 115.6 19.7 6.9e-11 41.7 1.0 3.9 3 0 0 3 3 3 3 WW domain C2 PF00168.25 CCC68538.1 - 1.1e-15 57.1 0.1 3.1e-15 55.7 0.1 1.8 1 0 0 1 1 1 1 C2 domain Endonuclea_NS_2 PF13930.1 CCC68538.1 - 2.7 8.0 9.7 1.2 9.1 1.3 2.8 2 1 1 3 3 3 0 DNA/RNA non-specific endonuclease Ribosomal_S8e PF01201.17 CCC68539.1 - 3.7e-40 137.1 7.2 1.6e-39 135.0 5.0 1.9 1 1 0 1 1 1 1 Ribosomal protein S8e Sas10_Utp3 PF04000.10 CCC68540.1 - 6.6e-13 48.6 1.8 6.6e-13 48.6 1.2 2.0 2 0 0 2 2 2 1 Sas10/Utp3/C1D family DUF4407 PF14362.1 CCC68540.1 - 0.21 10.5 9.2 0.018 14.0 2.8 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Vpu PF00558.14 CCC68540.1 - 0.89 9.1 4.2 3.3 7.3 2.9 2.0 1 0 0 1 1 1 0 Vpu protein Syntaxin_2 PF14523.1 CCC68540.1 - 2.5 8.1 7.2 4.7 7.3 0.3 3.4 3 1 0 3 3 3 0 Syntaxin-like protein Vfa1 PF08432.5 CCC68541.1 - 5.4e-44 150.3 6.9 6.5e-44 150.1 4.8 1.1 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DinB_2 PF12867.2 CCC68541.1 - 0.14 12.4 0.2 0.46 10.8 0.0 1.8 1 1 1 2 2 2 0 DinB superfamily DUF904 PF06005.7 CCC68541.1 - 0.23 11.7 8.3 0.68 10.2 5.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Pkinase PF00069.20 CCC68542.1 - 5.8e-53 179.6 0.0 8.9e-52 175.7 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68542.1 - 2.8e-25 88.8 0.5 2.7e-24 85.6 0.2 2.3 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC68542.1 - 1.6e-06 27.2 0.0 0.00034 19.6 0.0 2.6 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CCC68542.1 - 0.02 14.6 0.0 0.36 10.5 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family ArfGap PF01412.13 CCC68543.1 - 1.1e-22 79.9 1.7 1.1e-22 79.9 1.2 2.4 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf UBA PF00627.26 CCC68543.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain zf-C2H2 PF00096.21 CCC68544.1 - 5.2e-13 48.5 13.3 8.9e-07 28.9 1.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC68544.1 - 1.8e-11 43.5 11.3 7.8e-06 25.8 0.6 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCC68544.1 - 3.4e-08 33.4 8.7 0.0011 19.0 1.3 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CCC68544.1 - 1.7e-07 31.2 13.7 2.6e-06 27.4 1.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-BED PF02892.10 CCC68544.1 - 8.4e-05 22.2 5.2 0.061 13.0 0.9 3.0 2 0 0 2 2 2 2 BED zinc finger zf-Di19 PF05605.7 CCC68544.1 - 0.00011 22.2 3.0 0.00021 21.3 2.1 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-met PF12874.2 CCC68544.1 - 0.0017 18.5 7.2 0.49 10.6 1.6 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CCC68544.1 - 0.002 17.9 0.9 0.002 17.9 0.6 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger PyrI_C PF02748.10 CCC68544.1 - 0.015 14.7 0.5 0.19 11.1 0.1 2.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2_2 PF12756.2 CCC68544.1 - 0.03 14.4 6.2 1.1 9.4 0.4 2.9 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 CCC68544.1 - 6.2 6.6 6.8 11 5.7 1.2 2.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Mito_carr PF00153.22 CCC68546.1 - 9.9e-72 236.7 1.1 3.8e-25 87.4 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CCC68546.1 - 0.0016 18.5 4.9 0.16 12.0 0.1 4.6 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.1 CCC68546.1 - 0.0052 16.3 0.1 0.63 9.7 0.0 3.6 3 0 0 3 3 3 1 EF-hand domain pair DEAD PF00270.24 CCC68547.1 - 1.8e-42 144.7 0.2 5.1e-42 143.2 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC68547.1 - 1.2e-25 89.1 0.1 4.4e-25 87.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC68547.1 - 0.00027 20.8 0.0 0.00027 20.8 0.0 2.7 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCC68547.1 - 0.15 12.1 1.1 1.3 9.1 0.8 2.3 1 1 0 1 1 1 0 AAA domain Mss4 PF04421.8 CCC68548.1 - 9.1e-15 54.2 0.3 6.4e-10 38.7 0.1 2.2 2 0 0 2 2 2 2 Mss4 protein eIF-6 PF01912.13 CCC68549.1 - 7.8e-85 282.9 0.3 9.9e-85 282.6 0.2 1.1 1 0 0 1 1 1 1 eIF-6 family zf-C2H2 PF00096.21 CCC68550.1 - 0.00033 20.8 1.5 0.00033 20.8 1.0 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC68550.1 - 0.00062 19.9 2.9 0.00062 19.9 2.0 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 CCC68550.1 - 0.0045 17.1 0.4 0.0045 17.1 0.3 3.3 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 CCC68550.1 - 0.0062 16.7 15.9 0.0068 16.6 0.6 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCC68551.1 - 4.1e-09 36.2 6.2 0.00092 19.4 0.5 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC68551.1 - 6.7e-05 22.9 9.0 0.00017 21.6 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC68551.1 - 7e-05 22.8 7.3 0.07 13.4 0.5 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 CCC68551.1 - 0.0043 17.1 4.8 0.0083 16.3 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCC68551.1 - 0.11 12.6 3.7 0.15 12.2 0.0 2.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CCC68551.1 - 0.18 12.0 6.1 10 6.5 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc-finger domain zf-BED PF02892.10 CCC68551.1 - 4 7.2 8.8 3.4 7.5 0.6 2.8 2 1 0 3 3 3 0 BED zinc finger B12D PF06522.6 CCC68552.1 - 1.7e-05 24.4 0.0 2e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit MmgE_PrpD PF03972.9 CCC68553.1 - 1e-150 501.8 0.0 1.2e-150 501.5 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Nic96 PF04097.9 CCC68554.1 - 4.7e-207 688.9 13.4 5.6e-207 688.6 9.3 1.1 1 0 0 1 1 1 1 Nup93/Nic96 ERCC4 PF02732.10 CCC68554.1 - 0.017 14.9 0.4 8.3 6.1 0.0 3.5 2 1 1 3 3 3 0 ERCC4 domain PPI_Ypi1 PF07491.6 CCC68555.1 - 1.7e-21 75.5 11.0 5.4e-21 73.9 7.6 1.9 1 1 0 1 1 1 1 Protein phosphatase inhibitor SR-25 PF10500.4 CCC68555.1 - 0.00052 19.5 13.0 0.00064 19.2 9.0 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Cwf_Cwc_15 PF04889.7 CCC68555.1 - 0.0071 16.0 11.4 0.01 15.5 7.9 1.3 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 CCC68555.1 - 0.067 11.2 12.1 0.076 11.0 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SRP-alpha_N PF04086.8 CCC68555.1 - 0.088 12.1 6.9 0.11 11.9 4.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Host_attach PF10116.4 CCC68555.1 - 0.41 10.8 2.8 0.51 10.5 1.6 1.6 1 1 0 1 1 1 0 Protein required for attachment to host cells Herpes_DNAp_acc PF04929.7 CCC68555.1 - 2.8 6.7 7.2 3.3 6.5 5.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Nucleo_P87 PF07267.6 CCC68555.1 - 5.6 5.5 9.6 6.4 5.3 6.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 JAB PF01398.16 CCC68556.1 - 7.6e-34 115.8 0.2 7.6e-34 115.8 0.1 1.7 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 CCC68556.1 - 1.1e-25 89.9 4.8 3.1e-25 88.5 3.3 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 CCC68556.1 - 1.1e-08 34.6 0.0 2.1e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CCC68556.1 - 0.12 11.8 2.6 0.3 10.5 0.0 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0172) zf-UBP PF02148.14 CCC68557.1 - 7.1e-09 35.6 0.2 2e-08 34.2 0.1 1.7 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH PF00443.24 CCC68557.1 - 1.7e-06 27.3 5.1 1.8e-05 23.9 3.5 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_M24 PF00557.19 CCC68558.1 - 9.8e-55 185.3 0.0 1.3e-54 184.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CCC68558.1 - 2.4e-24 85.2 0.0 6.3e-24 83.8 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Citrate_synt PF00285.16 CCC68559.1 - 2e-92 309.6 0.0 2.3e-92 309.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Hat1_N PF10394.4 CCC68561.1 - 1e-35 123.1 1.1 2e-35 122.2 0.8 1.5 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_3 PF13302.1 CCC68561.1 - 0.00029 21.0 0.0 0.00054 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCC68561.1 - 0.00041 20.4 0.1 0.00076 19.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCC68561.1 - 0.00063 19.7 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCC68561.1 - 0.0042 17.2 0.0 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain EAP30 PF04157.11 CCC68562.1 - 6.8e-53 179.1 0.0 7.6e-53 178.9 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family PseudoU_synth_1 PF01416.15 CCC68563.1 - 5.5e-26 91.0 0.0 1e-16 61.2 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase Sulfate_transp PF00916.15 CCC68564.1 - 5.6e-60 202.7 7.0 1.1e-59 201.7 4.8 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CCC68564.1 - 7.2e-29 99.2 3.0 2.5e-28 97.5 2.0 2.0 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CCC68564.1 - 7.4e-21 73.7 0.1 6.1e-20 70.7 0.0 2.2 2 0 0 2 2 2 1 STAS domain ETF_alpha PF00766.14 CCC68565.1 - 2.8e-31 106.9 0.1 4.8e-31 106.2 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 CCC68565.1 - 1.3e-30 106.2 0.0 2.2e-30 105.5 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain EF-hand_5 PF13202.1 CCC68565.1 - 0.064 12.6 0.0 2 7.8 0.0 2.6 2 0 0 2 2 2 0 EF hand DUF4047 PF13256.1 CCC68566.1 - 0.075 12.9 2.0 0.32 10.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) PolyA_pol PF01743.15 CCC68567.1 - 1.5e-30 105.9 0.0 3.2e-30 104.9 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 CCC68567.1 - 7.3e-07 28.6 0.0 2.4e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 CCC68567.1 - 0.0066 16.2 2.8 0.01 15.6 0.2 2.6 3 1 0 3 3 3 1 tRNA nucleotidyltransferase domain 2 putative SEP PF08059.8 CCC68567.1 - 0.083 13.2 0.2 1.2 9.5 0.0 2.7 3 0 0 3 3 3 0 SEP domain AP2 PF00847.15 CCC68567.1 - 0.15 12.2 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 AP2 domain JmjC PF02373.17 CCC68568.1 - 3.6e-40 136.7 4.0 5.9e-40 136.0 0.4 2.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.12 CCC68568.1 - 3.7e-13 48.7 2.6 3.7e-13 48.7 1.8 2.4 2 0 0 2 2 2 1 jmjN domain zf-H2C2_2 PF13465.1 CCC68568.1 - 6.1e-07 29.4 12.2 6.3e-07 29.3 5.0 2.8 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCC68568.1 - 1.5e-06 28.1 16.5 0.0016 18.6 2.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC68568.1 - 1.1e-05 25.3 12.3 0.0013 18.9 0.9 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCC68568.1 - 0.019 14.8 8.6 0.056 13.3 1.9 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 CCC68568.1 - 0.3 11.0 5.4 1.9 8.4 3.7 2.3 1 1 0 1 1 1 0 Zinc ribbon domain zf-C2H2_jaz PF12171.3 CCC68568.1 - 0.37 11.0 10.4 0.18 12.0 2.3 2.5 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding ADK PF00406.17 CCC68569.1 - 7.8e-43 145.9 0.0 9.7e-43 145.6 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 CCC68569.1 - 2.5e-13 49.4 0.0 4.6e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 CCC68569.1 - 7.1e-07 29.2 0.0 2e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCC68569.1 - 1.8e-05 25.0 0.0 3.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCC68569.1 - 0.0025 18.6 0.0 0.0042 17.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 CCC68569.1 - 0.0095 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI 6PF2K PF01591.13 CCC68569.1 - 0.026 13.6 0.3 6.4 5.7 0.0 2.6 3 0 0 3 3 3 0 6-phosphofructo-2-kinase Zeta_toxin PF06414.7 CCC68569.1 - 0.048 12.7 0.0 0.27 10.3 0.0 2.0 1 1 0 1 1 1 0 Zeta toxin dNK PF01712.14 CCC68569.1 - 0.053 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase DUF1227 PF06777.6 CCC68570.1 - 2e-58 196.2 0.6 5.2e-58 194.8 0.4 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 CCC68570.1 - 1.6e-51 174.1 3.1 2.7e-51 173.4 2.1 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CCC68570.1 - 1.7e-45 154.9 0.0 6.5e-45 153.0 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 CCC68570.1 - 0.0032 16.9 0.1 0.94 8.9 0.0 2.7 3 0 0 3 3 3 2 DEAD/DEAH box helicase SNF2_N PF00176.18 CCC68570.1 - 0.0075 15.1 0.2 0.37 9.5 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain ResIII PF04851.10 CCC68570.1 - 0.034 13.9 0.1 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Sec63 PF02889.11 CCC68571.1 - 1.1e-171 570.1 4.7 8.1e-89 297.9 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CCC68571.1 - 8.5e-49 165.2 0.1 2.5e-30 105.1 0.0 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CCC68571.1 - 2.1e-17 63.5 0.4 3.3e-09 36.8 0.0 2.8 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCC68571.1 - 4.3e-09 36.1 0.1 4.2e-08 32.9 0.0 2.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCC68571.1 - 6.9e-07 29.4 0.4 0.08 13.0 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 CCC68571.1 - 2.3e-05 24.6 0.2 0.019 15.1 0.0 3.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCC68571.1 - 3.7e-05 23.7 0.1 0.0011 18.9 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_19 PF13245.1 CCC68571.1 - 7e-05 22.5 0.0 0.029 14.1 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CCC68571.1 - 0.0019 17.7 0.0 0.052 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CCC68571.1 - 0.018 14.2 0.0 2.7 7.1 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein IstB_IS21 PF01695.12 CCC68571.1 - 0.029 13.7 0.0 3.2 7.1 0.0 3.3 4 0 0 4 4 4 0 IstB-like ATP binding protein Rad17 PF03215.10 CCC68572.1 - 1.2e-104 350.9 5.9 5.5e-75 253.0 0.4 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 CCC68572.1 - 2.6e-06 27.5 0.1 2.9e-05 24.1 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CCC68572.1 - 0.022 15.5 2.3 0.27 12.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCC68572.1 - 0.059 12.8 0.0 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 CCC68572.1 - 0.06 13.0 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCC68572.1 - 0.076 13.1 0.6 0.46 10.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CCC68572.1 - 0.097 12.3 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 NTPase Glutaredoxin PF00462.19 CCC68573.1 - 4.1e-17 61.9 0.0 3.3e-16 58.9 0.0 2.2 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 CCC68573.1 - 1.5e-13 50.2 0.0 5.4e-13 48.5 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin AhpC-TSA PF00578.16 CCC68573.1 - 1.1e-05 25.1 0.1 3.8e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.1 CCC68573.1 - 2.7e-05 24.1 0.7 0.00062 19.8 0.1 3.0 2 1 1 3 3 3 2 Thioredoxin-like SH3BGR PF04908.10 CCC68573.1 - 0.0073 16.2 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein DIM1 PF02966.11 CCC68573.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Mitosis protein DIM1 ArsC PF03960.10 CCC68573.1 - 0.049 13.7 0.0 0.17 11.9 0.0 1.9 2 0 0 2 2 2 0 ArsC family Methyltransf_11 PF08241.7 CCC68574.1 - 5.4e-12 46.0 0.0 9.1e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC68574.1 - 2.7e-11 43.7 0.3 5.7e-11 42.6 0.1 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCC68574.1 - 3.3e-11 43.5 0.0 8.4e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC68574.1 - 6e-11 42.1 0.0 9.1e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC68574.1 - 3.3e-10 40.5 0.0 7.5e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC68574.1 - 7.4e-09 35.5 0.0 1.1e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCC68574.1 - 2.1e-06 27.0 0.0 3.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 CCC68574.1 - 0.0031 16.5 0.0 0.0059 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 CCC68574.1 - 0.0038 16.3 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 CCC68574.1 - 0.0048 16.9 0.0 0.06 13.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCC68574.1 - 0.0067 16.1 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCC68574.1 - 0.01 15.1 0.0 0.032 13.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 CCC68574.1 - 0.065 12.3 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 CCC68574.1 - 0.067 12.7 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AAA_12 PF13087.1 CCC68575.1 - 4e-61 205.8 0.1 1.3e-60 204.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCC68575.1 - 6.4e-44 150.2 0.3 6.4e-44 150.2 0.2 2.9 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.1 CCC68575.1 - 7.3e-11 42.0 0.0 1.2e-09 38.0 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCC68575.1 - 1.2e-10 40.9 0.0 2.5e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 CCC68575.1 - 1.8e-07 30.9 2.4 0.17 11.4 0.0 4.4 4 0 0 4 4 4 3 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 CCC68575.1 - 0.0007 19.7 0.0 0.0026 17.8 0.0 2.0 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Arch_ATPase PF01637.13 CCC68575.1 - 0.0018 18.0 0.1 0.018 14.7 0.0 2.7 2 2 0 2 2 2 1 Archaeal ATPase PhoH PF02562.11 CCC68575.1 - 0.0023 17.1 0.1 0.011 14.9 0.1 2.2 1 1 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.1 CCC68575.1 - 0.0027 17.8 0.0 0.01 15.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC68575.1 - 0.0038 17.2 0.0 0.0086 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 CCC68575.1 - 0.0065 16.6 0.0 0.027 14.6 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) 14-3-3 PF00244.15 CCC68576.1 - 4.2e-115 382.7 4.6 4.2e-115 382.7 3.2 1.3 1 1 0 1 1 1 1 14-3-3 protein DUF885 PF05960.6 CCC68576.1 - 0.019 14.1 0.4 0.019 14.1 0.3 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) FlaF PF07309.6 CCC68576.1 - 0.027 14.3 0.6 0.072 12.9 0.4 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF E1_dh PF00676.15 CCC68577.1 - 9e-121 402.1 0.0 1.1e-120 401.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 CCC68577.1 - 0.0096 14.8 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase KRTAP7 PF15034.1 CCC68577.1 - 0.13 12.9 4.8 0.28 11.8 0.1 2.9 2 2 0 2 2 2 0 KRTAP type 7 family Rad51 PF08423.6 CCC68578.1 - 1.7e-112 374.5 0.0 1.9e-112 374.3 0.0 1.0 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 CCC68578.1 - 2.3e-10 40.2 0.0 3.1e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCC68578.1 - 0.00017 21.7 0.1 0.00038 20.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain RecA PF00154.16 CCC68578.1 - 0.00018 20.6 0.0 0.00024 20.2 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DUF2205 PF10224.4 CCC68580.1 - 1.2e-08 34.3 4.9 1.3e-08 34.2 3.4 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) CRM1_C PF08767.6 CCC68580.1 - 0.011 14.7 0.1 0.012 14.5 0.1 1.0 1 0 0 1 1 1 0 CRM1 C terminal TSC22 PF01166.13 CCC68580.1 - 0.15 12.0 2.4 0.32 10.9 0.3 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family Kinesin-relat_1 PF12711.2 CCC68580.1 - 0.37 11.2 4.9 2.6 8.5 3.4 1.9 1 1 0 1 1 1 0 Kinesin motor EMP70 PF02990.11 CCC68581.1 - 1.8e-210 699.8 13.5 2.5e-210 699.3 9.4 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Rax2 PF12768.2 CCC68582.1 - 6.8e-60 202.6 4.9 6.8e-60 202.6 3.4 5.6 4 1 2 6 6 6 4 Cortical protein marker for cell polarity Actin PF00022.14 CCC68583.1 - 3.8e-52 177.0 0.0 4.9e-52 176.6 0.0 1.1 1 0 0 1 1 1 1 Actin SMC_N PF02463.14 CCC68584.1 - 6.5e-69 231.5 50.4 5.2e-68 228.5 34.9 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCC68584.1 - 3.4e-28 98.0 1.9 6.3e-28 97.1 0.0 2.5 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCC68584.1 - 3.7e-07 30.4 57.3 0.00092 19.2 8.7 5.7 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.1 CCC68584.1 - 2.7e-05 23.6 0.0 5.8e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 CCC68584.1 - 0.0027 16.9 44.3 0.047 12.8 2.9 5.7 3 2 2 5 5 5 4 Reovirus sigma C capsid protein Aminotran_1_2 PF00155.16 CCC68586.1 - 2.7e-39 135.1 0.0 3.9e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCC68586.1 - 0.00095 18.3 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DnaJ PF00226.26 CCC68587.1 - 3e-26 90.9 1.0 4.6e-25 87.1 1.4 2.2 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 CCC68587.1 - 4e-19 68.2 0.2 1.8e-16 59.7 0.0 3.0 2 1 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCC68587.1 - 2.5e-10 40.2 15.5 3.8e-08 33.2 11.6 2.7 1 1 2 3 3 3 3 DnaJ central domain Cytochrom_c3_2 PF14537.1 CCC68587.1 - 0.0051 17.1 1.6 0.0051 17.1 1.1 2.3 2 0 0 2 2 2 1 Cytochrome c3 Cytochrome_C7 PF14522.1 CCC68587.1 - 0.92 9.1 12.4 0.29 10.7 6.4 1.9 1 1 0 1 1 1 0 Cytochrome c7 Sulfate_transp PF00916.15 CCC68589.1 - 7.7e-84 281.0 2.7 7.7e-84 281.0 1.9 1.8 2 1 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 CCC68589.1 - 1.7e-31 107.7 2.3 6.1e-31 105.9 1.6 2.0 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 CCC68589.1 - 3.5e-06 26.4 0.0 6.8e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 CCC68589.1 - 0.0017 18.3 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain Nyv1_N PF09426.5 CCC68590.1 - 4.2e-57 191.6 0.8 4.9e-57 191.4 0.1 1.4 2 0 0 2 2 2 1 Vacuolar R-SNARE Nyv1 N terminal Synaptobrevin PF00957.16 CCC68590.1 - 5.5e-27 93.2 3.6 8.7e-27 92.5 2.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Fzo_mitofusin PF04799.8 CCC68590.1 - 0.048 13.0 1.1 0.073 12.4 0.8 1.3 1 0 0 1 1 1 0 fzo-like conserved region PHD PF00628.24 CCC68592.1 - 0.013 15.1 1.9 0.049 13.3 1.3 1.9 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.20 CCC68593.1 - 3.2e-72 242.8 0.9 2.8e-71 239.7 0.6 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68593.1 - 1.2e-40 139.1 0.5 9.7e-39 132.9 0.3 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 CCC68593.1 - 2.1e-19 68.7 0.0 4.2e-19 67.7 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 CCC68593.1 - 1.7e-05 23.9 0.1 5e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCC68593.1 - 0.00013 21.1 0.1 0.00024 20.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC68593.1 - 0.013 15.1 0.0 0.073 12.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 CCC68593.1 - 0.019 14.2 1.7 0.14 11.5 0.0 2.8 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL WaaY PF06176.6 CCC68593.1 - 0.06 12.5 0.2 0.11 11.6 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) F-box-like PF12937.2 CCC68594.1 - 6.2e-06 25.8 0.1 1.1e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCC68594.1 - 6.6e-05 22.4 0.8 0.00014 21.4 0.6 1.4 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 CCC68594.1 - 0.01 15.6 0.1 0.02 14.7 0.1 1.5 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Fungal_trans PF04082.13 CCC68595.1 - 6.6e-35 120.2 2.9 1.7e-34 118.8 2.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC68595.1 - 4e-09 36.2 8.2 6.8e-09 35.4 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_6 PF12697.2 CCC68596.1 - 4.3e-21 75.8 0.0 5.9e-21 75.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC68596.1 - 3.5e-15 56.1 0.0 2.3e-10 40.4 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCC68596.1 - 2.1e-13 50.2 0.0 7e-13 48.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 CCC68596.1 - 5.3e-08 32.2 1.3 3e-06 26.5 0.9 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 CCC68596.1 - 5.3e-05 23.5 0.0 0.022 14.9 0.0 2.2 2 0 0 2 2 2 2 Thioesterase domain Ndr PF03096.9 CCC68596.1 - 0.00079 17.9 0.0 0.041 12.3 0.0 2.4 1 1 0 2 2 2 1 Ndr family Esterase PF00756.15 CCC68596.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 CCC68596.1 - 0.015 14.9 0.0 0.061 12.8 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.6 CCC68596.1 - 0.017 14.8 0.0 4.1 7.0 0.0 2.5 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 CCC68596.1 - 0.044 12.9 0.1 2.7 7.1 0.0 2.6 3 0 0 3 3 3 0 Prolyl oligopeptidase family Chlorophyllase PF07224.6 CCC68596.1 - 0.074 11.8 0.0 0.13 10.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase Ser_hydrolase PF06821.8 CCC68596.1 - 0.083 12.4 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase Chlorophyllase2 PF12740.2 CCC68596.1 - 0.087 11.6 0.0 0.41 9.4 0.0 2.1 2 1 0 2 2 2 0 Chlorophyllase enzyme DUF706 PF05153.10 CCC68596.1 - 0.15 11.3 4.2 0.071 12.4 0.8 1.9 2 1 0 2 2 2 0 Family of unknown function (DUF706) Prp18 PF02840.10 CCC68597.1 - 0.0076 16.0 0.1 0.016 15.0 0.1 1.5 1 0 0 1 1 1 1 Prp18 domain Tub_2 PF04525.7 CCC68598.1 - 0.075 12.4 0.0 0.075 12.4 0.0 1.0 1 0 0 1 1 1 0 Tubby C 2 SKIP_SNW PF02731.10 CCC68599.1 - 6.7e-41 139.3 9.1 1.2e-40 138.5 6.3 1.4 1 0 0 1 1 1 1 SKIP/SNW domain DUF327 PF03885.8 CCC68599.1 - 4.5 7.0 8.4 1.2 8.9 2.5 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF327) Prophage_tail PF06605.6 CCC68600.1 - 0.077 11.9 1.5 0.095 11.6 1.0 1.0 1 0 0 1 1 1 0 Prophage endopeptidase tail TMCO5 PF14992.1 CCC68600.1 - 0.14 11.3 11.0 0.16 11.0 7.6 1.1 1 0 0 1 1 1 0 TMCO5 family FTA4 PF13093.1 CCC68600.1 - 0.19 11.1 2.7 0.24 10.8 1.8 1.0 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 EST1_DNA_bind PF10373.4 CCC68600.1 - 0.22 10.7 1.7 0.34 10.0 1.2 1.3 1 0 0 1 1 1 0 Est1 DNA/RNA binding domain RNA_pol_3_Rpc31 PF11705.3 CCC68600.1 - 0.26 11.1 12.4 0.3 10.9 8.6 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Laps PF10169.4 CCC68600.1 - 0.42 10.8 2.5 0.52 10.5 1.7 1.3 1 0 0 1 1 1 0 Learning-associated protein AAA_23 PF13476.1 CCC68600.1 - 2.6 8.3 8.8 3.1 8.0 6.1 1.1 1 0 0 1 1 1 0 AAA domain Daxx PF03344.10 CCC68600.1 - 3.1 6.1 7.6 3.3 6.1 5.3 1.0 1 0 0 1 1 1 0 Daxx Family XhlA PF10779.4 CCC68600.1 - 3.3 7.6 6.1 11 6.0 4.2 2.0 1 1 0 1 1 1 0 Haemolysin XhlA RTX PF02382.10 CCC68600.1 - 4.1 5.5 5.2 4.8 5.3 3.6 1.1 1 0 0 1 1 1 0 RTX N-terminal domain DUF778 PF05608.7 CCC68600.1 - 8.6 6.2 6.7 9.5 6.1 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF778) EPSP_synthase PF00275.15 CCC68601.1 - 2.4e-134 447.9 0.0 3.6e-134 447.3 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 CCC68601.1 - 5.5e-99 330.3 0.0 8.3e-99 329.7 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 CCC68601.1 - 9.3e-66 221.6 0.0 1.5e-65 220.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 CCC68601.1 - 3.7e-38 130.8 0.0 1.6e-36 125.5 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 CCC68601.1 - 2.7e-21 75.3 0.1 1.1e-20 73.4 0.0 2.1 2 0 0 2 2 2 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 CCC68601.1 - 1.1e-15 57.8 0.0 3.9e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 CCC68601.1 - 2.7e-07 30.1 0.0 6.2e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase AAA_17 PF13207.1 CCC68601.1 - 1.8e-06 28.8 0.0 5.6e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCC68601.1 - 0.0072 16.2 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCC68601.1 - 0.022 14.6 0.0 0.11 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain adh_short PF00106.20 CCC68602.1 - 9e-05 22.4 0.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase CH PF00307.26 CCC68603.1 - 1.5e-74 246.9 0.2 2.9e-20 72.2 0.2 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 CCC68603.1 - 4.1e-08 32.7 0.0 0.038 13.6 0.0 4.3 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.1 CCC68603.1 - 6.2e-05 23.0 1.1 0.00032 20.7 0.2 2.5 2 0 0 2 2 2 1 EF-hand domain pair BMF PF15185.1 CCC68603.1 - 0.055 12.7 0.0 4.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Bcl-2-modifying factor, apoptosis EF-hand_1 PF00036.27 CCC68603.1 - 0.11 11.8 0.1 13 5.3 0.0 3.3 3 0 0 3 3 3 0 EF hand Apc9 PF12856.2 CCC68604.1 - 3.8e-15 55.8 0.7 7.6e-15 54.8 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 9 CDC45 PF02724.9 CCC68605.1 - 4.2e-213 708.8 0.1 4.8e-213 708.6 0.1 1.0 1 0 0 1 1 1 1 CDC45-like protein Sigma70_ner PF04546.8 CCC68605.1 - 0.21 11.1 10.1 0.42 10.1 7.0 1.4 1 0 0 1 1 1 0 Sigma-70, non-essential region PBP1_TM PF14812.1 CCC68605.1 - 5.7 7.3 12.5 18 5.7 8.6 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sporozoite_P67 PF05642.6 CCC68605.1 - 5.8 4.6 5.5 8.9 4.0 3.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 CCC68605.1 - 6.3 4.5 15.7 8.7 4.1 10.9 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2413 PF10310.4 CCC68605.1 - 6.7 5.4 10.2 10 4.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Sdh5 PF03937.11 CCC68606.1 - 1.1e-24 85.9 0.5 1.6e-24 85.3 0.3 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase PCI PF01399.22 CCC68607.1 - 2.2e-09 37.5 0.3 9.3e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 PCI domain Smg4_UPF3 PF03467.10 CCC68608.1 - 5.2e-20 72.1 1.6 5.2e-20 72.1 1.1 2.2 1 1 1 2 2 2 1 Smg-4/UPF3 family LSM PF01423.17 CCC68609.1 - 8e-19 66.9 0.3 1.4e-18 66.1 0.0 1.5 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.1 CCC68609.1 - 0.0018 18.1 0.1 0.0034 17.2 0.1 1.7 1 1 0 1 1 1 1 Ataxin 2 SM domain ABC_tran PF00005.22 CCC68614.1 - 2.9e-52 176.6 0.5 4.6e-25 88.4 0.1 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 CCC68614.1 - 3.4e-39 134.2 31.2 2.2e-24 85.7 7.6 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_21 PF13304.1 CCC68614.1 - 4e-16 59.8 8.4 6.1e-07 29.6 3.2 4.9 4 1 0 4 4 3 3 AAA domain DUF258 PF03193.11 CCC68614.1 - 3e-09 36.2 0.4 0.00035 19.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 CCC68614.1 - 4.1e-09 36.0 5.7 0.00013 21.2 0.3 3.6 3 1 0 3 3 2 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCC68614.1 - 2.6e-08 34.6 0.0 0.018 15.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCC68614.1 - 3.1e-08 33.8 0.0 0.0062 16.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 CCC68614.1 - 3.1e-08 33.0 5.4 0.0061 15.6 0.0 4.9 5 1 0 5 5 5 2 AAA ATPase domain AAA_18 PF13238.1 CCC68614.1 - 1.6e-07 31.7 0.2 0.0087 16.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 CCC68614.1 - 4.3e-07 29.5 0.0 0.0054 16.1 0.0 3.8 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 CCC68614.1 - 9e-07 28.3 4.4 0.0079 15.6 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 CCC68614.1 - 1.3e-06 28.6 0.6 0.018 15.1 0.0 3.4 3 1 0 3 3 2 2 AAA domain T2SE PF00437.15 CCC68614.1 - 7.2e-06 25.1 0.3 0.03 13.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.7 CCC68614.1 - 2.1e-05 24.2 0.0 0.013 15.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.1 CCC68614.1 - 5.1e-05 23.2 0.0 0.049 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CCC68614.1 - 0.0001 21.8 2.7 0.23 10.8 0.1 2.6 3 0 0 3 3 2 2 AAA-like domain Arch_ATPase PF01637.13 CCC68614.1 - 0.00011 22.0 0.1 0.11 12.1 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase MMR_HSR1 PF01926.18 CCC68614.1 - 0.00015 21.7 0.0 0.36 10.8 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_19 PF13245.1 CCC68614.1 - 0.00016 21.3 0.4 0.06 13.1 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain FtsK_SpoIIIE PF01580.13 CCC68614.1 - 0.00026 20.5 1.0 0.019 14.4 0.1 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 CCC68614.1 - 0.00026 20.8 0.1 1.7 8.6 0.0 3.4 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 CCC68614.1 - 0.00036 20.4 0.0 1.1 9.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 CCC68614.1 - 0.00037 20.6 0.1 0.87 9.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase cobW PF02492.14 CCC68614.1 - 0.00048 19.6 0.1 0.35 10.3 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CCC68614.1 - 0.0014 18.3 1.6 1.6 8.4 0.4 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.9 CCC68614.1 - 0.0021 17.1 0.0 0.39 9.6 0.0 2.4 2 0 0 2 2 2 1 KAP family P-loop domain AAA_33 PF13671.1 CCC68614.1 - 0.0025 17.6 0.2 3.4 7.5 0.1 2.5 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 CCC68614.1 - 0.0031 17.2 0.2 6.2 6.4 0.0 3.2 3 0 0 3 3 3 0 NTPase Pox_A32 PF04665.7 CCC68614.1 - 0.0044 16.3 0.6 0.15 11.3 0.0 2.8 3 0 0 3 3 3 1 Poxvirus A32 protein AAA_30 PF13604.1 CCC68614.1 - 0.0046 16.5 1.1 2.7 7.5 0.2 2.3 2 0 0 2 2 2 2 AAA domain DUF87 PF01935.12 CCC68614.1 - 0.0048 16.7 4.1 1.2 8.9 0.4 3.7 3 0 0 3 3 3 1 Domain of unknown function DUF87 Adeno_IVa2 PF02456.10 CCC68614.1 - 0.005 15.5 0.2 0.016 13.8 0.0 1.8 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_23 PF13476.1 CCC68614.1 - 0.0055 17.0 10.1 0.035 14.4 0.2 3.6 2 2 1 3 3 3 1 AAA domain AAA PF00004.24 CCC68614.1 - 0.0083 16.3 0.0 9.4 6.4 0.0 3.4 4 0 0 4 4 2 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.13 CCC68614.1 - 0.01 15.4 0.2 2.7 7.5 0.0 3.2 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family Miro PF08477.8 CCC68614.1 - 0.012 16.1 0.0 2.9 8.3 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein NB-ARC PF00931.17 CCC68614.1 - 0.014 14.2 1.3 3.3 6.4 0.0 2.6 3 0 0 3 3 2 0 NB-ARC domain KaiC PF06745.8 CCC68614.1 - 0.025 13.7 0.4 1 8.4 0.0 3.1 3 0 0 3 3 3 0 KaiC ABC_ATPase PF09818.4 CCC68614.1 - 0.035 12.6 0.3 1 7.8 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class UPF0079 PF02367.12 CCC68614.1 - 0.04 13.5 0.7 0.87 9.2 0.2 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 CCC68614.1 - 0.041 13.4 0.1 7.4 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 CCC68614.1 - 0.054 13.2 0.3 2.3 7.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 CCC68614.1 - 0.075 12.5 0.5 4.5 6.7 0.2 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 CCC68614.1 - 0.095 12.2 3.8 5.1 6.5 0.0 2.8 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein DUF2075 PF09848.4 CCC68614.1 - 0.099 11.6 0.1 0.38 9.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Dynamin_N PF00350.18 CCC68614.1 - 1.1 9.0 6.3 21 4.8 0.2 3.6 4 0 0 4 4 4 0 Dynamin family Brix PF04427.13 CCC68615.1 - 6.9e-40 136.7 0.6 9.1e-40 136.3 0.4 1.1 1 0 0 1 1 1 1 Brix domain DUF468 PF04318.7 CCC68615.1 - 0.01 16.3 0.0 0.035 14.6 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF468) DUF2611 PF11022.3 CCC68616.1 - 3.4e-18 65.4 0.0 3.7e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) Transgly_assoc PF04226.8 CCC68616.1 - 0.13 12.3 0.1 0.17 12.0 0.1 1.1 1 0 0 1 1 1 0 Transglycosylase associated protein SIN1 PF05422.7 CCC68617.1 - 6.3e-29 100.8 5.0 1.1e-13 50.6 1.3 2.6 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 CCC68617.1 - 0.013 15.4 0.1 0.04 13.8 0.0 1.9 1 0 0 1 1 1 0 GLUT4 regulating protein TUG RBD PF02196.10 CCC68617.1 - 0.02 14.6 0.0 0.065 13.0 0.0 1.8 1 0 0 1 1 1 0 Raf-like Ras-binding domain RNase_T PF00929.19 CCC68618.1 - 6.9e-32 110.9 0.1 1.1e-30 107.0 0.0 2.1 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 CCC68618.1 - 0.0018 17.7 0.0 0.0056 16.1 0.0 1.9 1 1 0 1 1 1 1 3'-5' exonuclease RasGAP PF00616.14 CCC68619.1 - 3.8e-37 127.8 3.8 1.4e-35 122.7 1.1 3.5 2 1 0 2 2 2 2 GTPase-activator protein for Ras-like GTPase DUF3876 PF12992.2 CCC68620.1 - 0.032 14.1 0.8 0.078 12.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3876) DUF2623 PF11115.3 CCC68620.1 - 0.18 11.7 1.0 4 7.4 0.0 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF2623) ATG19_autophagy PF12744.2 CCC68621.1 - 5.1e-20 71.7 8.0 7.4e-20 71.2 5.6 1.3 1 0 0 1 1 1 1 Autophagy protein Atg19, Atg8-binding DUF221 PF02714.10 CCC68622.1 - 8.9e-103 343.5 17.4 1.7e-102 342.6 12.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCC68622.1 - 1.5e-39 135.0 3.0 1.5e-39 135.0 2.1 2.6 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CCC68622.1 - 1.3e-27 95.5 0.1 3.4e-27 94.1 0.1 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 CCC68622.1 - 9.8e-11 42.0 1.3 6.2e-10 39.4 0.9 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) ARHGEF5_35 PF15441.1 CCC68622.1 - 0.047 12.4 1.8 0.068 11.9 1.3 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 DUF2236 PF09995.4 CCC68622.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2236) ADH_zinc_N_2 PF13602.1 CCC68623.1 - 0.11 13.3 0.0 0.61 10.9 0.0 2.0 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Spore_YhaL PF14147.1 CCC68623.1 - 0.16 11.4 0.4 0.26 10.7 0.3 1.3 1 0 0 1 1 1 0 Sporulation protein YhaL CENP-S PF15630.1 CCC68624.1 - 3e-27 94.5 0.0 3.8e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CCC68624.1 - 2.3e-05 23.8 0.0 2.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CCC68624.1 - 0.0017 18.0 0.1 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 CCC68624.1 - 0.0024 17.9 0.0 0.0049 16.9 0.0 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 PCP_red PF08369.5 CCC68624.1 - 0.027 14.3 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Proto-chlorophyllide reductase 57 kD subunit TFIID-18kDa PF02269.11 CCC68624.1 - 0.091 12.5 0.0 0.13 12.0 0.0 1.4 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit DUF3337 PF11816.3 CCC68625.1 - 7.9e-65 219.4 6.6 7.9e-65 219.4 4.6 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3337) WD40 PF00400.27 CCC68625.1 - 1.9e-11 43.3 3.3 0.00033 20.4 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat E1-E2_ATPase PF00122.15 CCC68626.1 - 3.1e-61 206.3 6.4 3.1e-61 206.3 4.5 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCC68626.1 - 2.9e-23 83.4 0.0 7.8e-23 82.0 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCC68626.1 - 9.8e-14 51.9 0.0 2.7e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCC68626.1 - 3.5e-11 42.3 0.0 8.2e-11 41.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCC68626.1 - 0.0015 18.2 0.1 0.0035 16.9 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Phage_fiber_C PF06820.7 CCC68626.1 - 0.033 14.3 0.1 0.13 12.3 0.0 2.0 1 0 0 1 1 1 0 Putative prophage tail fibre C-terminus Hydrolase_like2 PF13246.1 CCC68626.1 - 0.054 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Kelch_6 PF13964.1 CCC68628.1 - 8.4e-15 54.2 5.8 1.5e-08 34.4 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CCC68628.1 - 4.7e-14 51.8 5.8 0.00045 19.9 0.0 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 CCC68628.1 - 1.7e-12 46.7 1.4 9.3e-05 21.9 0.0 4.8 4 1 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 CCC68628.1 - 4.8e-11 42.4 2.0 0.0017 18.4 0.0 5.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.10 CCC68628.1 - 8e-08 31.7 0.4 0.00069 19.2 0.0 4.4 4 0 0 4 4 4 1 Kelch motif Kelch_5 PF13854.1 CCC68628.1 - 7.5e-06 25.7 0.1 0.0094 15.8 0.0 3.8 3 0 0 3 3 3 1 Kelch motif D-ser_dehydrat PF14031.1 CCC68629.1 - 1.4e-20 73.2 0.0 3.4e-20 72.0 0.0 1.7 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 CCC68629.1 - 2.7e-08 33.6 0.0 4.7e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3554 PF12074.3 CCC68630.1 - 6e-44 150.8 19.6 1.4e-27 96.9 3.5 6.0 3 3 2 5 5 5 2 Domain of unknown function (DUF3554) HEAT_2 PF13646.1 CCC68630.1 - 1.4e-36 124.6 20.8 1.8e-09 37.7 0.0 12.4 7 3 8 15 15 15 10 HEAT repeats HEAT PF02985.17 CCC68630.1 - 4.1e-30 101.1 18.8 0.0012 18.7 0.0 18.5 25 0 0 25 25 25 7 HEAT repeat HEAT_EZ PF13513.1 CCC68630.1 - 2.3e-27 94.7 20.9 0.012 16.0 0.0 16.4 12 4 5 18 18 18 7 HEAT-like repeat CLASP_N PF12348.3 CCC68630.1 - 2.3e-20 72.9 0.0 8.8e-05 21.9 0.0 7.5 5 1 1 8 8 8 4 CLASP N terminal Vac14_Fab1_bd PF12755.2 CCC68630.1 - 2.7e-11 43.6 3.2 2.7 8.4 0.0 10.3 9 4 0 10 10 10 3 Vacuolar 14 Fab1-binding region Ipi1_N PF12333.3 CCC68630.1 - 9.4e-05 22.3 0.0 1.3 9.0 0.0 5.4 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation MCR_alpha_N PF02745.10 CCC68630.1 - 0.093 11.9 4.0 0.2 10.7 1.6 2.4 3 0 0 3 3 3 0 Methyl-coenzyme M reductase alpha subunit, N-terminal domain Hist_deacetyl PF00850.14 CCC68632.1 - 2.7e-81 273.2 0.0 3.5e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain MT-A70 PF05063.9 CCC68633.1 - 4e-56 189.3 0.2 8.3e-56 188.3 0.1 1.6 1 0 0 1 1 1 1 MT-A70 COX6A PF02046.10 CCC68634.1 - 5.9e-41 139.0 1.2 6.7e-41 138.8 0.8 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa WD40 PF00400.27 CCC68635.1 - 3.1e-16 58.5 0.2 0.0015 18.3 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCC68635.1 - 0.006 15.3 2.3 0.054 12.2 0.4 2.7 1 1 0 2 2 2 1 Nup133 N terminal like COX5B PF01215.14 CCC68636.1 - 6e-56 187.8 0.0 6.8e-56 187.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Transp_cyt_pur PF02133.10 CCC68638.1 - 3.1e-15 55.6 28.7 3.1e-15 55.6 19.9 2.0 2 0 0 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4579 PF15158.1 CCC68638.1 - 8.7 5.8 7.7 1.4 8.3 1.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4579) AcetylCoA_hydro PF02550.10 CCC68639.1 - 5.8e-73 244.8 0.1 1.6e-72 243.4 0.0 1.7 2 0 0 2 2 2 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 CCC68639.1 - 7e-39 132.9 0.0 1.2e-38 132.2 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain CitF PF04223.7 CCC68639.1 - 0.03 13.0 0.1 0.061 11.9 0.1 1.4 1 1 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) CoA_trans PF01144.18 CCC68639.1 - 0.067 12.3 0.0 0.22 10.6 0.0 2.0 2 0 0 2 2 2 0 Coenzyme A transferase Pkinase PF00069.20 CCC68640.1 - 1.1e-70 237.7 0.0 1.3e-70 237.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68640.1 - 4.6e-32 111.1 0.0 5.9e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC68640.1 - 0.0061 15.5 0.0 0.031 13.2 0.0 2.0 1 1 1 3 3 3 1 Kinase-like Kdo PF06293.9 CCC68640.1 - 0.078 12.0 0.1 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC68640.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BNR PF02012.15 CCC68641.1 - 4.4e-14 49.9 48.2 0.5 10.4 0.2 13.0 12 0 0 12 12 12 9 BNR/Asp-box repeat Mo-co_dimer PF03404.11 CCC68641.1 - 0.0095 15.5 1.0 26 4.4 0.0 4.9 5 0 0 5 5 5 1 Mo-co oxidoreductase dimerisation domain PSII_BNR PF14870.1 CCC68641.1 - 0.021 13.8 7.4 2.3 7.1 0.0 4.9 7 0 0 7 7 7 0 Photosynthesis system II assembly factor YCF48 Exo_endo_phos PF03372.18 CCC68643.1 - 8.4e-14 52.0 0.0 1.2e-13 51.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 CCC68643.1 - 2.4e-13 49.7 0.2 1.6e-11 43.8 0.0 3.0 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 CCC68643.1 - 4.7e-09 36.0 0.5 1e-08 34.9 0.3 1.6 1 0 0 1 1 1 1 GRF zinc finger Rft-1 PF04506.8 CCC68644.1 - 2.3e-176 587.4 42.8 2.6e-176 587.2 29.7 1.0 1 0 0 1 1 1 1 Rft protein CBFD_NFYB_HMF PF00808.18 CCC68645.1 - 7.6e-26 89.9 0.0 1e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCC68645.1 - 7.3e-06 26.0 0.0 1.2e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID_20kDa PF03847.8 CCC68645.1 - 0.013 15.7 0.2 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 Transcription initiation factor TFIID subunit A Bromo_TP PF07524.8 CCC68645.1 - 0.014 15.1 0.0 0.025 14.3 0.0 1.4 1 1 0 1 1 1 0 Bromodomain associated Lon_C PF05362.8 CCC68646.1 - 1.3e-65 220.5 0.0 3.6e-65 219.1 0.0 1.8 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 CCC68646.1 - 5.2e-34 117.7 8.1 5.2e-34 117.7 5.6 2.5 3 1 0 3 3 3 1 ATP-dependent protease La (LON) domain AAA PF00004.24 CCC68646.1 - 2.9e-23 82.5 0.0 8.2e-23 81.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCC68646.1 - 1.6e-07 31.4 0.0 6e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 CCC68646.1 - 1.3e-06 28.1 0.0 3.5e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 CCC68646.1 - 3.2e-06 26.6 0.0 7.4e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_17 PF13207.1 CCC68646.1 - 5.5e-06 27.2 0.3 0.00017 22.4 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.1 CCC68646.1 - 3.4e-05 23.9 0.3 0.001 19.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCC68646.1 - 9.2e-05 22.5 0.1 0.0023 17.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.6 CCC68646.1 - 0.0005 18.8 0.0 0.001 17.8 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_14 PF13173.1 CCC68646.1 - 0.00065 19.5 0.0 0.0025 17.6 0.0 2.1 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCC68646.1 - 0.0011 18.0 0.0 0.016 14.2 0.0 2.5 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 CCC68646.1 - 0.0029 17.7 0.0 0.071 13.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 CCC68646.1 - 0.0031 17.7 3.7 0.0073 16.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain SKI PF01202.17 CCC68646.1 - 0.013 15.4 0.5 0.038 13.8 0.0 2.1 2 0 0 2 2 2 0 Shikimate kinase NTPase_1 PF03266.10 CCC68646.1 - 0.019 14.6 0.4 0.55 9.9 0.0 3.0 2 1 1 3 3 3 0 NTPase IstB_IS21 PF01695.12 CCC68646.1 - 0.025 14.0 0.0 0.05 13.0 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 CCC68646.1 - 0.049 12.8 0.2 0.18 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MCM PF00493.18 CCC68647.1 - 2.7e-141 470.1 0.0 3.8e-141 469.6 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 CCC68647.1 - 1.1e-28 100.1 31.4 1.1e-28 100.1 21.8 3.6 5 0 0 5 5 5 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 CCC68647.1 - 9.1e-14 51.9 0.0 2.4e-13 50.6 0.0 1.8 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCC68647.1 - 2.5e-09 36.5 0.0 2.4e-07 30.1 0.0 2.5 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 CCC68647.1 - 2.2e-07 30.7 0.0 5.1e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCC68647.1 - 0.00071 19.1 0.0 0.004 16.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCC68647.1 - 0.0013 18.2 0.1 0.0079 15.6 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.24 CCC68647.1 - 0.015 15.5 0.0 0.043 14.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Cut8_N PF14482.1 CCC68647.1 - 1.5 8.8 7.6 0.35 10.8 1.0 2.6 2 0 0 2 2 2 0 Cut8 proteasome-binding domain Nol1_Nop2_Fmu PF01189.12 CCC68648.1 - 4.5e-76 255.9 0.0 2.1e-60 204.4 0.0 2.1 1 1 1 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 CCC68648.1 - 7.8e-05 22.7 0.1 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 CCC68648.1 - 0.0052 16.8 0.0 0.01 15.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC68648.1 - 0.0062 17.1 0.0 0.025 15.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Gag_spuma PF03276.9 CCC68649.1 - 0.037 12.3 0.2 0.05 11.9 0.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein HhH-GPD PF00730.20 CCC68651.1 - 2.6e-12 46.9 0.0 4.1e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein COX15-CtaA PF02628.10 CCC68652.1 - 3.6e-99 331.4 8.9 4.3e-99 331.1 6.2 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein DUF747 PF05346.6 CCC68653.1 - 5.3e-90 301.8 24.5 7.1e-90 301.4 17.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF4131 PF13567.1 CCC68653.1 - 0.17 11.2 3.0 0.29 10.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) RPAP2_Rtr1 PF04181.8 CCC68654.1 - 5.7e-19 67.9 0.2 1.1e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family Ribosomal_S13_N PF08069.7 CCC68655.1 - 4e-28 97.0 0.1 8.5e-28 95.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 CCC68655.1 - 4.8e-23 80.7 0.1 1.2e-22 79.3 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S15 GDI PF00996.13 CCC68656.1 - 5e-212 703.9 0.0 6.3e-212 703.6 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 CCC68656.1 - 0.0054 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Copper-fist PF00649.13 CCC68657.1 - 1.6e-22 78.4 1.1 4.7e-22 76.8 0.8 1.9 1 0 0 1 1 1 1 Copper fist DNA binding domain Zn_clus PF00172.13 CCC68658.1 - 6.4e-09 35.5 25.9 0.00032 20.5 1.3 4.3 4 0 0 4 4 4 3 Fungal Zn(2)-Cys(6) binuclear cluster domain PDDEXK_1 PF12705.2 CCC68658.1 - 1.2 8.4 6.1 1.6 8.0 0.0 2.7 4 0 0 4 4 4 0 PD-(D/E)XK nuclease superfamily zf-C2H2 PF00096.21 CCC68659.1 - 9.2e-08 31.9 11.4 0.00081 19.5 0.4 3.1 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC68659.1 - 3.2e-06 27.0 6.1 0.0021 18.2 0.1 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCC68659.1 - 2.9e-05 24.1 7.4 0.00071 19.7 0.1 3.6 3 0 0 3 3 3 1 Zinc-finger double domain zf-BED PF02892.10 CCC68659.1 - 0.0081 15.8 7.5 0.023 14.4 0.4 2.5 2 0 0 2 2 2 1 BED zinc finger FYVE PF01363.16 CCC68659.1 - 0.25 11.2 2.8 0.63 9.9 1.9 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-met PF12874.2 CCC68659.1 - 0.34 11.1 7.6 0.7 10.1 0.3 3.1 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCC68659.1 - 0.91 9.7 0.0 0.91 9.7 0.0 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CCC68659.1 - 1.4 9.2 9.5 15 6.0 0.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain Cryptochrome_C PF12546.3 CCC68659.1 - 4.9 7.8 15.1 0.64 10.7 6.3 2.6 2 0 0 2 2 2 0 Blue/Ultraviolet sensing protein C terminal rve PF00665.21 CCC68660.1 - 2.5e-17 63.1 0.0 3.5e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain zf-H2C2 PF09337.5 CCC68660.1 - 0.074 12.4 0.6 0.52 9.7 0.0 2.2 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger MUG113 PF13455.1 CCC68662.1 - 1.4e-08 35.0 0.1 7.9e-07 29.4 0.1 2.3 1 1 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 CCC68662.1 - 1.1e-07 32.0 0.1 2e-05 24.9 0.1 2.3 1 1 0 1 1 1 1 T5orf172 domain LUC7 PF03194.10 CCC68664.1 - 2.7e-69 233.5 11.2 3.3e-69 233.2 7.8 1.0 1 0 0 1 1 1 1 LUC7 N_terminus BioW PF03744.8 CCC68664.1 - 0.026 13.9 0.9 0.04 13.3 0.6 1.4 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase KLRAQ PF10205.4 CCC68664.1 - 0.054 13.5 4.0 0.14 12.2 2.8 1.6 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein AAA_23 PF13476.1 CCC68664.1 - 0.44 10.8 6.3 0.61 10.3 4.4 1.2 1 0 0 1 1 1 0 AAA domain Seryl_tRNA_N PF02403.17 CCC68664.1 - 0.71 9.9 8.2 2.9 7.9 2.1 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF2418 PF10332.4 CCC68665.1 - 5.3e-22 77.9 4.2 1.6e-21 76.4 2.9 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) Prenyltrans PF00432.16 CCC68666.1 - 8.7e-43 143.5 7.0 6.7e-12 44.7 0.2 5.2 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCC68666.1 - 6.3e-18 65.2 0.0 7.9e-13 48.8 0.0 3.0 1 1 2 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 CCC68666.1 - 0.0036 17.3 0.0 2.2 8.3 0.0 2.5 1 1 1 2 2 2 2 Prenyltransferase-like UBX PF00789.15 CCC68667.1 - 2.5e-15 56.2 0.0 5.3e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain SRP14 PF02290.10 CCC68668.1 - 1.4e-20 72.9 0.3 1.4e-20 72.9 0.2 1.7 1 1 1 2 2 2 1 Signal recognition particle 14kD protein PMT PF02366.13 CCC68669.1 - 5e-63 212.7 19.7 5e-63 212.7 13.7 2.2 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCC68669.1 - 2.8e-46 157.4 1.4 4.3e-46 156.8 0.0 1.9 2 0 0 2 2 2 1 MIR domain Fibrinogen_BP PF08017.6 CCC68669.1 - 0.0036 15.5 6.0 0.0054 15.0 4.1 1.1 1 0 0 1 1 1 1 Fibrinogen binding protein DMP1 PF07263.6 CCC68669.1 - 0.021 13.5 12.3 0.03 13.0 8.6 1.1 1 0 0 1 1 1 0 Dentin matrix protein 1 (DMP1) SDA1 PF05285.7 CCC68669.1 - 0.96 8.6 11.9 1.5 8.0 8.2 1.1 1 0 0 1 1 1 0 SDA1 PMT PF02366.13 CCC68670.1 - 2.5e-84 282.4 20.5 2.5e-84 282.4 14.2 1.8 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCC68670.1 - 2.5e-47 160.9 0.2 3.5e-47 160.3 0.1 1.2 1 0 0 1 1 1 1 MIR domain PCI PF01399.22 CCC68671.1 - 1.1e-18 67.5 0.2 7.5e-18 64.7 0.0 2.5 2 0 0 2 2 2 1 PCI domain TPR_16 PF13432.1 CCC68671.1 - 3.4e-06 27.5 0.4 0.097 13.3 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_15 PF13429.1 CCC68671.1 - 0.0014 17.7 1.9 0.0032 16.5 1.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat DDRGK PF09756.4 CCC68671.1 - 0.0022 17.4 0.1 0.0022 17.4 0.0 2.2 2 0 0 2 2 2 1 DDRGK domain TPR_12 PF13424.1 CCC68671.1 - 0.0036 17.1 5.6 0.24 11.3 0.5 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CCC68671.1 - 0.0037 17.3 11.3 0.015 15.4 0.8 4.1 4 1 0 4 4 3 1 Anaphase-promoting complex, cyclosome, subunit 3 DehI PF10778.4 CCC68671.1 - 0.0073 15.8 0.1 0.019 14.5 0.1 1.6 1 0 0 1 1 1 1 Halocarboxylic acid dehydrogenase DehI SNAP PF14938.1 CCC68671.1 - 0.023 13.8 11.6 0.077 12.1 0.8 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 CCC68671.1 - 0.025 14.2 5.6 3 7.5 0.1 3.8 5 0 0 5 5 5 0 TPR repeat DFF40 PF09230.5 CCC68671.1 - 0.22 10.8 9.5 0.16 11.3 1.6 2.7 3 0 0 3 3 3 0 DNA fragmentation factor 40 kDa TPR_19 PF14559.1 CCC68671.1 - 0.24 11.7 3.4 11 6.4 0.2 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.4 CCC68671.1 - 0.31 10.9 3.8 3.5 7.5 0.0 3.3 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCC68671.1 - 2 9.0 6.3 16 6.2 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DLD PF14878.1 CCC68671.1 - 2.1 8.4 9.0 0.2 11.7 1.1 2.9 1 1 1 3 3 3 0 Death-like domain of SPT6 Rapamycin_bind PF08771.6 CCC68671.1 - 2.4 8.3 7.7 16 5.6 0.0 4.0 5 1 1 6 6 5 0 Rapamycin binding domain TPR_2 PF07719.12 CCC68671.1 - 2.6 8.1 13.3 7.4 6.7 0.1 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat zf-met PF12874.2 CCC68672.1 - 3.6e-07 30.1 0.7 7.1e-07 29.2 0.5 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCC68672.1 - 8.1e-05 22.6 1.3 0.00017 21.6 0.9 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.7 CCC68672.1 - 0.0086 15.7 1.0 0.021 14.4 0.7 1.6 1 0 0 1 1 1 1 DBF zinc finger MAAL_C PF07476.6 CCC68672.1 - 0.011 14.7 0.1 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus P2_Phage_GpR PF06891.6 CCC68672.1 - 0.075 12.8 0.2 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) zf-C2H2 PF00096.21 CCC68672.1 - 0.13 12.7 1.3 0.28 11.6 0.9 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 CCC68672.1 - 0.13 12.2 1.4 0.31 10.9 1.0 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger KGK PF08872.5 CCC68672.1 - 0.87 9.7 5.6 0.24 11.5 0.1 2.3 1 1 0 2 2 2 0 KGK domain FlxA PF14282.1 CCC68673.1 - 0.0033 17.3 15.1 0.0033 17.3 10.5 3.7 4 0 0 4 4 4 1 FlxA-like protein Striatin PF08232.7 CCC68673.1 - 0.0074 16.6 6.7 0.0074 16.6 4.6 3.2 2 1 0 2 2 2 1 Striatin family Reo_sigmaC PF04582.7 CCC68673.1 - 0.28 10.3 4.3 0.4 9.8 3.0 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Mitofilin PF09731.4 CCC68673.1 - 0.48 9.0 48.2 0.63 8.6 33.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Pox_A_type_inc PF04508.7 CCC68673.1 - 5.6 7.0 14.9 1.1 9.2 1.0 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat ArsA_ATPase PF02374.10 CCC68674.1 - 1.7e-115 385.2 0.1 2e-115 385.0 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 CCC68674.1 - 4.5e-12 45.7 0.7 9.6e-12 44.7 0.4 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Fer4_NifH PF00142.13 CCC68674.1 - 0.00066 18.9 0.1 0.0013 18.0 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_31 PF13614.1 CCC68674.1 - 0.0022 17.9 0.0 0.01 15.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 CCC68674.1 - 0.015 14.7 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CCC68674.1 - 0.022 14.1 0.1 0.048 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Plasmodium_Vir PF05795.6 CCC68674.1 - 0.051 12.7 2.7 0.081 12.1 1.8 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein PhoH PF02562.11 CCC68674.1 - 0.055 12.7 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 CCC68674.1 - 0.18 10.9 0.1 0.63 9.1 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Pkinase PF00069.20 CCC68675.1 - 7.2e-72 241.6 0.0 9.7e-72 241.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68675.1 - 1.6e-35 122.4 0.0 2.2e-35 122.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CCC68675.1 - 3.4e-17 62.3 2.0 5.5e-17 61.6 0.7 1.9 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 CCC68675.1 - 0.0071 15.3 1.2 4.9 6.0 0.0 3.2 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.9 CCC68675.1 - 0.036 13.1 0.1 0.059 12.4 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DNA_pol_B PF00136.16 CCC68676.1 - 2.4e-135 451.9 3.5 3.2e-135 451.5 2.4 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CCC68676.1 - 2e-88 296.4 0.0 3.1e-88 295.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CCC68676.1 - 4.6e-23 81.0 3.8 8.7e-23 80.1 2.6 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 CCC68676.1 - 2.7e-05 23.0 5.5 0.00019 20.2 0.7 2.3 2 0 0 2 2 2 2 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.1 CCC68676.1 - 0.0023 17.7 0.5 0.012 15.4 0.4 2.2 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 CCC68676.1 - 0.0028 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB UDPGP PF01704.13 CCC68677.1 - 8.4e-48 162.8 0.0 1.2e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 CCC68677.1 - 0.095 12.7 0.0 0.26 11.3 0.0 1.8 1 0 0 1 1 1 0 MobA-like NTP transferase domain TFIIA PF03153.8 CCC68678.1 - 0.29 11.0 18.4 0.4 10.5 12.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3835 PF12927.2 CCC68678.1 - 6.2 7.8 6.3 1.5 9.7 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3835) MCPVI PF02993.9 CCC68678.1 - 6.3 6.8 8.9 8.2 6.4 6.1 1.1 1 0 0 1 1 1 0 Minor capsid protein VI LisH PF08513.6 CCC68679.1 - 0.0004 20.0 3.4 0.00076 19.1 2.3 1.5 1 0 0 1 1 1 1 LisH Peptidase_M22 PF00814.20 CCC68680.1 - 4.5e-70 236.2 0.0 5.6e-70 235.8 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 CCC68680.1 - 0.028 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Carbamoyltransferase BcrAD_BadFG PF01869.15 CCC68680.1 - 0.079 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Nse4_C PF08743.5 CCC68681.1 - 6.8e-24 83.7 2.9 3.1e-23 81.6 0.8 2.8 2 1 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 CCC68681.1 - 1.4e-09 37.6 0.0 3.4e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF1178 PF06676.6 CCC68681.1 - 0.015 15.5 0.6 0.052 13.7 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1178) DUF1053 PF06327.9 CCC68681.1 - 0.85 10.0 7.7 0.5 10.7 1.8 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1053) Homeobox PF00046.24 CCC68682.1 - 7.2e-17 60.7 1.4 1.2e-16 60.0 1.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCC68682.1 - 0.0046 16.6 0.1 0.013 15.1 0.0 1.8 1 0 0 1 1 1 1 Homeobox KN domain TPR_11 PF13414.1 CCC68683.1 - 0.0026 17.3 0.2 0.47 10.1 0.0 3.2 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 CCC68683.1 - 0.0079 16.0 1.7 27 5.0 0.0 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCC68683.1 - 0.039 14.6 0.0 13 6.6 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 CCC68684.1 - 5.8e-72 241.9 0.0 6.6e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68684.1 - 1.7e-31 109.2 0.0 3.1e-31 108.3 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC68684.1 - 0.0012 17.8 0.0 0.0027 16.7 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CCC68684.1 - 0.011 15.4 0.1 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF676 PF05057.9 CCC68685.1 - 5.8e-55 185.9 0.6 1.1e-54 185.0 0.4 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 CCC68685.1 - 0.0013 17.7 0.1 0.0013 17.7 0.1 2.2 3 0 0 3 3 3 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 CCC68685.1 - 0.0047 16.5 0.1 0.012 15.2 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CCC68685.1 - 0.011 15.3 0.2 0.035 13.7 0.1 1.9 1 1 0 1 1 1 0 PGAP1-like protein SH3_9 PF14604.1 CCC68686.1 - 2.5e-06 26.9 0.1 5.7e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCC68686.1 - 4.9e-06 25.8 0.2 3.7e-05 23.0 0.0 2.5 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 CCC68686.1 - 0.00021 20.6 0.1 0.00043 19.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Nup84_Nup100 PF04121.8 CCC68687.1 - 3.3e-215 715.9 14.9 3.8e-215 715.6 10.3 1.0 1 0 0 1 1 1 1 Nuclear pore protein 84 / 107 DUF1340 PF07067.6 CCC68687.1 - 0.037 13.1 0.1 0.071 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1340) DUF1762 PF08574.5 CCC68688.1 - 4.3e-21 75.1 16.1 4.3e-21 75.1 11.2 3.8 3 1 0 3 3 3 1 Protein of unknown function (DUF1762) adh_short PF00106.20 CCC68689.1 - 1.9e-28 99.4 0.0 3.4e-28 98.6 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCC68689.1 - 1.1e-13 51.2 0.0 2.2e-12 47.0 0.0 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 CCC68689.1 - 1.8e-08 34.4 0.0 2.5e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 CCC68689.1 - 0.00098 17.8 0.0 0.0014 17.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCC68689.1 - 0.0058 16.6 0.0 0.0087 16.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCC68689.1 - 0.08 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Actin PF00022.14 CCC68690.1 - 5.1e-94 314.8 0.0 5.2e-93 311.5 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCC68690.1 - 0.00015 20.4 0.0 0.23 9.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein ADH_zinc_N_2 PF13602.1 CCC68691.1 - 1.7e-13 51.5 0.0 3.5e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCC68691.1 - 1.3e-07 31.2 0.0 2.4e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCC68691.1 - 3.1e-05 23.6 0.0 7.2e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 CCC68691.1 - 0.079 13.2 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PX PF00787.19 CCC68692.1 - 3.8e-22 78.2 0.2 4.7e-21 74.7 0.0 2.4 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 CCC68692.1 - 4.1e-08 32.7 11.2 7.1e-08 31.9 1.8 2.4 2 0 0 2 2 2 2 Vps5 C terminal like CCDC-167 PF15188.1 CCC68692.1 - 0.0027 17.6 1.1 0.0027 17.6 0.8 3.0 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 167 SpoU_methylase PF00588.14 CCC68693.1 - 5.7e-26 91.0 0.0 1.2e-25 90.0 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family APG6 PF04111.7 CCC68694.1 - 0.0085 15.1 5.9 0.01 14.9 4.1 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 ISG65-75 PF11727.3 CCC68694.1 - 0.0089 15.1 2.0 0.0099 14.9 1.4 1.1 1 0 0 1 1 1 1 Invariant surface glycoprotein Filament PF00038.16 CCC68694.1 - 0.012 15.0 4.8 0.014 14.8 3.3 1.0 1 0 0 1 1 1 0 Intermediate filament protein SNARE PF05739.14 CCC68694.1 - 0.013 15.1 0.6 0.042 13.5 0.1 2.1 2 0 0 2 2 2 0 SNARE domain BLOC1_2 PF10046.4 CCC68694.1 - 0.016 15.3 1.0 0.016 15.3 0.7 2.2 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3086 PF11285.3 CCC68694.1 - 0.027 13.2 1.3 0.032 13.0 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) IncA PF04156.9 CCC68694.1 - 0.036 13.6 3.5 0.05 13.1 2.4 1.3 1 0 0 1 1 1 0 IncA protein Spc7 PF08317.6 CCC68694.1 - 0.039 12.6 4.4 0.053 12.1 3.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein RmuC PF02646.11 CCC68694.1 - 0.054 12.3 1.7 0.071 11.9 0.7 1.5 1 1 0 1 1 1 0 RmuC family zf-C4H2 PF10146.4 CCC68694.1 - 0.063 13.2 7.7 0.15 12.0 3.7 1.9 1 1 1 2 2 2 0 Zinc finger-containing protein CENP-F_leu_zip PF10473.4 CCC68694.1 - 0.091 12.6 6.0 0.11 12.3 4.2 1.1 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3922 PF13059.1 CCC68694.1 - 0.093 12.9 0.6 0.22 11.7 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3992) Atg14 PF10186.4 CCC68694.1 - 0.094 11.6 2.0 0.1 11.5 1.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Streptin-Immun PF11083.3 CCC68694.1 - 0.11 12.4 3.7 0.078 12.9 1.3 1.7 1 1 1 2 2 2 0 Lantibiotic streptin immunity protein YlqD PF11068.3 CCC68694.1 - 0.12 12.3 3.4 0.17 11.9 2.4 1.4 1 1 0 1 1 1 0 YlqD protein TMCO5 PF14992.1 CCC68694.1 - 0.16 11.0 6.5 0.21 10.6 4.5 1.1 1 0 0 1 1 1 0 TMCO5 family Phage_GP20 PF06810.6 CCC68694.1 - 0.2 11.0 8.6 0.64 9.4 5.9 1.8 1 1 0 1 1 1 0 Phage minor structural protein GP20 K-box PF01486.12 CCC68694.1 - 0.26 11.0 4.3 0.24 11.2 2.1 1.6 1 1 0 1 1 1 0 K-box region CENP-Q PF13094.1 CCC68694.1 - 0.26 11.2 5.4 0.36 10.8 3.6 1.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TBCA PF02970.11 CCC68694.1 - 0.28 11.2 5.5 0.32 11.0 2.8 1.8 1 1 1 2 2 2 0 Tubulin binding cofactor A TMPIT PF07851.8 CCC68694.1 - 0.3 10.0 3.2 0.3 10.1 1.0 1.6 1 1 1 2 2 2 0 TMPIT-like protein DegQ PF08181.6 CCC68694.1 - 0.36 10.5 9.8 1.6 8.4 0.2 2.6 3 0 0 3 3 3 0 DegQ (SacQ) family Exonuc_VII_L PF02601.10 CCC68694.1 - 0.47 9.6 3.4 0.53 9.4 2.3 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2115 PF09888.4 CCC68694.1 - 0.78 9.8 3.1 2.7 8.0 2.3 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) TMF_DNA_bd PF12329.3 CCC68694.1 - 2 8.2 9.7 1.9 8.3 4.6 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Ribosomal_S13 PF00416.17 CCC68694.1 - 2.1 8.8 4.2 13 6.2 2.9 2.1 1 1 0 1 1 1 0 Ribosomal protein S13/S18 Mito_carr PF00153.22 CCC68695.1 - 2.3e-51 171.4 4.7 5.9e-21 73.9 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein Frataxin_Cyay PF01491.11 CCC68696.1 - 2.1e-32 111.1 0.0 2.8e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain UCH PF00443.24 CCC68697.1 - 2e-50 171.3 0.2 3.1e-50 170.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC68697.1 - 6.1e-14 52.1 0.1 1.3e-10 41.2 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Frataxin_Cyay PF01491.11 CCC68697.1 - 0.26 11.0 0.0 0.26 11.0 0.0 3.8 5 0 0 5 5 5 0 Frataxin-like domain RRM_1 PF00076.17 CCC68698.1 - 6.2e-55 182.7 0.2 1.2e-18 66.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC68698.1 - 1.7e-29 101.5 0.2 1.8e-10 40.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC68698.1 - 6.7e-26 89.9 1.4 4.8e-09 35.9 0.2 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCC68698.1 - 0.0011 18.7 0.2 0.11 12.2 0.0 3.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif DUF1987 PF09345.5 CCC68698.1 - 0.047 13.4 1.0 1.7 8.4 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) DUF3421 PF11901.3 CCC68698.1 - 0.069 12.8 0.1 13 5.5 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3421) DFP PF04127.10 CCC68699.1 - 1.5e-15 57.2 0.0 7.3e-06 25.7 0.0 3.2 2 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Sds3 PF08598.6 CCC68700.1 - 2.3e-59 200.4 4.9 2.8e-59 200.1 3.4 1.1 1 0 0 1 1 1 1 Sds3-like Tim44 PF04280.10 CCC68700.1 - 0.075 13.0 0.9 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 Tim44-like domain Glyco_transf_15 PF01793.11 CCC68701.1 - 2.4e-120 401.4 12.7 3.3e-120 401.0 8.8 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Histone PF00125.19 CCC68702.1 - 2.5e-15 56.3 0.2 3.1e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCC68702.1 - 3.2e-05 23.8 0.1 5.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CCC68702.1 - 4.4e-05 23.3 0.2 6.2e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CCC68702.1 - 5e-05 23.3 0.1 7e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CCC68702.1 - 0.0012 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CCC68702.1 - 0.0042 16.7 0.0 0.0052 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 CCC68702.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 CCC68702.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 CCC68703.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCC68703.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCC68703.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCC68703.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DUF2416 PF10315.4 CCC68704.1 - 5.9e-34 116.5 1.3 9.5e-34 115.9 0.9 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) Dfp1_Him1_M PF08630.5 CCC68704.1 - 0.12 12.2 0.1 0.2 11.4 0.1 1.3 1 0 0 1 1 1 0 Dfp1/Him1, central region Aa_trans PF01490.13 CCC68705.1 - 2.6e-113 378.5 17.5 3e-113 378.4 12.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ICE2 PF08426.5 CCC68706.1 - 1.2e-163 544.5 32.9 1.4e-163 544.3 22.8 1.0 1 0 0 1 1 1 1 ICE2 DUF1253 PF06862.7 CCC68707.1 - 1.8e-163 544.0 7.7 2.8e-163 543.4 5.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) MRP-S25 PF13741.1 CCC68708.1 - 7.7e-90 300.3 7.2 8.9e-90 300.1 5.0 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 CCC68708.1 - 0.0011 18.8 2.6 0.01 15.7 0.1 2.7 2 1 1 3 3 3 1 Mitochondrial ribosomal protein S23 Iso_dh PF00180.15 CCC68709.1 - 5.1e-112 374.2 0.1 5.8e-112 374.0 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Pkinase PF00069.20 CCC68710.1 - 6.5e-38 130.3 0.0 1.1e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68710.1 - 1.5e-30 106.1 0.0 2.2e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC68710.1 - 6.4e-05 22.0 0.0 0.0001 21.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCC68710.1 - 0.016 14.9 0.0 0.078 12.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2431 PF10354.4 CCC68711.1 - 1.5e-57 194.1 0.1 2.7e-57 193.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) CLTH PF10607.4 CCC68712.1 - 1.3e-26 93.0 6.4 1.3e-26 93.0 4.4 2.7 2 2 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Nudix_N PF12535.3 CCC68712.1 - 0.034 13.5 0.0 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal Rad50_zn_hook PF04423.9 CCC68712.1 - 0.92 9.0 0.0 0.92 9.0 0.0 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif Iso_dh PF00180.15 CCC68713.1 - 1.2e-74 251.3 0.5 1.5e-74 251.0 0.3 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Complex1_LYR_2 PF13233.1 CCC68714.1 - 4.7e-13 49.5 3.1 8.9e-13 48.6 2.2 1.4 1 1 0 1 1 1 1 Complex1_LYR-like TBPIP PF07106.8 CCC68714.1 - 0.017 14.7 0.7 0.017 14.7 0.5 1.8 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Diphthamide_syn PF01866.12 CCC68716.1 - 6.4e-113 377.0 0.1 7.9e-113 376.7 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein SHQ1 PF04925.10 CCC68717.1 - 2e-65 219.7 0.8 3.2e-65 219.1 0.6 1.2 1 0 0 1 1 1 1 SHQ1 protein PIH1 PF08190.7 CCC68717.1 - 0.0052 16.2 0.0 0.0093 15.4 0.0 1.3 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 PH PF00169.24 CCC68718.1 - 1.1e-17 64.0 0.9 3.7e-17 62.4 0.6 1.9 1 0 0 1 1 1 1 PH domain Mob1_phocein PF03637.12 CCC68719.1 - 2.9e-70 235.4 0.0 3.8e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family 6PF2K PF01591.13 CCC68720.1 - 4.6e-83 277.6 0.4 7.9e-83 276.9 0.3 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCC68720.1 - 5.6e-32 111.0 0.5 2e-30 105.9 0.1 2.5 2 1 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 CCC68720.1 - 8e-09 35.5 0.0 3.3e-08 33.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCC68720.1 - 3e-06 28.0 0.0 1.2e-05 26.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCC68720.1 - 0.0026 16.8 0.0 0.0058 15.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.18 CCC68720.1 - 0.0043 16.9 0.2 0.11 12.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase APS_kinase PF01583.15 CCC68720.1 - 0.0095 15.5 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 CCC68720.1 - 0.0097 15.1 0.0 0.022 13.9 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Pox_A28 PF04584.9 CCC68720.1 - 0.01 15.7 0.6 0.028 14.3 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A28 family AAA_5 PF07728.9 CCC68720.1 - 0.016 14.9 0.1 2.5 7.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Metallopep PF12044.3 CCC68721.1 - 2.1e-165 550.3 0.0 2.6e-165 550.0 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 CCC68721.1 - 0.00069 19.5 0.1 0.0027 17.5 0.0 2.1 2 0 0 2 2 2 1 Jacalin-like lectin domain Reprolysin_3 PF13582.1 CCC68721.1 - 0.015 15.7 0.0 0.04 14.4 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 CCC68721.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 CCC68721.1 - 0.037 13.9 0.0 0.061 13.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12 Sec23_trunk PF04811.10 CCC68722.1 - 1.6e-67 227.4 0.1 3.1e-67 226.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCC68722.1 - 5.1e-23 80.4 0.3 1.3e-22 79.1 0.2 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCC68722.1 - 2.7e-16 59.8 0.0 6.1e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCC68722.1 - 7e-15 54.3 5.3 1.6e-14 53.2 3.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCC68722.1 - 5.8e-05 22.7 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 Gelsolin repeat AMP_N PF05195.11 CCC68722.1 - 0.051 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain DUF2756 PF10956.3 CCC68722.1 - 0.086 13.0 9.0 0.27 11.5 5.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2756) HisG PF01634.13 CCC68722.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 ATP phosphoribosyltransferase Methyltransf_12 PF08242.7 CCC68723.1 - 0.028 14.8 0.0 0.079 13.4 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 CCC68723.1 - 0.062 12.7 0.1 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase COX4 PF02936.9 CCC68724.1 - 6.3e-42 142.6 1.8 6.8e-42 142.5 1.3 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV DUF1289 PF06945.8 CCC68724.1 - 1.4 8.4 7.9 0.6 9.6 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1289) Ank_2 PF12796.2 CCC68725.1 - 2.1e-59 197.8 10.5 6.1e-22 77.7 0.5 3.5 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CCC68725.1 - 5.1e-36 120.6 3.7 3.3e-10 39.2 0.3 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 CCC68725.1 - 1.8e-28 98.3 0.3 5.1e-11 42.7 0.0 5.2 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCC68725.1 - 1.2e-26 92.1 3.3 1.3e-06 28.4 0.0 5.1 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCC68725.1 - 8.4e-26 87.4 0.1 1.9e-07 30.6 0.3 6.0 5 0 0 5 5 5 4 Ankyrin repeat Porin_3 PF01459.17 CCC68726.1 - 1.3e-58 198.5 2.0 1.4e-58 198.3 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Aminotran_1_2 PF00155.16 CCC68728.1 - 5.1e-68 229.6 0.0 5.8e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.8 CCC68728.1 - 0.00017 20.3 0.0 0.00026 19.7 0.0 1.2 1 0 0 1 1 1 1 Allinase Aminotran_5 PF00266.14 CCC68728.1 - 0.1 11.2 0.1 0.26 9.9 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class-V Ras PF00071.17 CCC68730.1 - 1.5e-57 193.4 0.0 1.9e-57 193.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC68730.1 - 3.6e-16 59.7 0.0 6.4e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC68730.1 - 6.7e-09 35.2 0.0 1.1e-08 34.5 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCC68730.1 - 0.00021 21.2 0.0 0.0044 16.9 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCC68730.1 - 0.00053 19.2 0.0 0.00065 18.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCC68730.1 - 0.0014 17.8 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCC68730.1 - 0.0042 15.8 0.0 0.0045 15.7 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arch_ATPase PF01637.13 CCC68730.1 - 0.019 14.6 0.0 0.027 14.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 CCC68730.1 - 0.038 14.2 0.1 0.065 13.5 0.1 1.7 1 1 0 1 1 1 0 ABC transporter Myb_DNA-bind_4 PF13837.1 CCC68731.1 - 3.8e-05 23.7 0.1 9.5e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MFS_1 PF07690.11 CCC68732.1 - 6e-40 137.0 21.2 3.7e-35 121.2 7.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCC68732.1 - 0.0024 16.1 5.9 0.0038 15.5 4.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) RNA_pol_Rpb5_C PF01191.14 CCC68732.1 - 0.14 11.7 0.1 0.29 10.7 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain RasGAP_C PF03836.10 CCC68733.1 - 0.012 15.2 3.9 0.023 14.3 2.7 1.4 1 0 0 1 1 1 0 RasGAP C-terminus Rhabdo_M1 PF03342.8 CCC68733.1 - 0.028 13.5 0.6 0.056 12.5 0.4 1.4 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) SUN PF03856.8 CCC68734.1 - 2.6e-104 347.9 16.4 2.6e-104 347.9 11.3 1.5 2 0 0 2 2 2 1 Beta-glucosidase (SUN family) Macoilin PF09726.4 CCC68734.1 - 0.1 10.8 9.4 0.12 10.6 6.5 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 CCC68734.1 - 0.69 9.7 5.2 0.94 9.3 3.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PepSY_2 PF13670.1 CCC68734.1 - 1.4 8.8 4.2 12 5.8 1.8 2.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain adh_short PF00106.20 CCC68735.1 - 8.6e-28 97.3 0.0 1.1e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCC68735.1 - 1.6e-15 57.5 0.0 2e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCC68735.1 - 5.7e-08 32.6 0.0 8.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 CCC68735.1 - 0.0015 17.7 0.0 0.095 11.8 0.0 2.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 CCC68735.1 - 0.0018 18.2 0.0 0.0035 17.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 CCC68735.1 - 0.0021 17.5 0.0 0.0049 16.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CCC68735.1 - 0.013 14.3 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 CCC68735.1 - 0.075 12.8 0.0 0.65 9.8 0.0 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Transket_pyr PF02779.19 CCC68736.1 - 7.8e-65 217.6 0.0 1.4e-64 216.8 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 CCC68736.1 - 2.6e-53 180.6 0.0 3.6e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Ribosomal_L6 PF00347.18 CCC68737.1 - 1.1e-27 96.2 11.9 8.2e-14 51.8 3.1 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 YbbR PF07949.7 CCC68737.1 - 0.017 15.2 2.4 1.8 8.7 0.4 3.1 1 1 2 3 3 3 0 YbbR-like protein SNF2_N PF00176.18 CCC68738.1 - 1.3e-84 283.5 0.7 1.3e-84 283.5 0.5 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.20 CCC68738.1 - 2.9e-22 78.3 0.1 1.2e-21 76.4 0.1 2.1 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 CCC68738.1 - 4.8e-19 67.9 0.5 6.8e-17 61.1 0.0 3.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SnAC PF14619.1 CCC68738.1 - 1.8e-13 50.4 0.5 1.8e-13 50.4 0.4 5.1 4 2 1 5 5 5 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 CCC68738.1 - 1.2e-05 25.0 6.0 1.2e-05 25.0 4.1 4.5 5 1 0 5 5 5 1 HSA Fungal_trans PF04082.13 CCC68739.1 - 1.4e-33 115.9 0.6 3e-33 114.8 0.4 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC68739.1 - 1.8e-11 43.7 11.8 3e-11 43.0 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fork_head PF00250.13 CCC68740.1 - 1.5e-34 117.8 0.5 3e-34 116.9 0.3 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CCC68740.1 - 1.1e-08 35.0 0.0 4e-08 33.2 0.0 2.0 2 0 0 2 2 2 1 FHA domain DUF904 PF06005.7 CCC68741.1 - 0.067 13.4 4.2 0.15 12.3 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Ribosomal_L13 PF00572.13 CCC68742.1 - 8.3e-26 90.5 0.1 1.4e-25 89.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 MSP7_C PF12948.2 CCC68742.1 - 0.084 13.1 0.5 0.14 12.4 0.0 1.5 2 0 0 2 2 2 0 MSP7-like protein C-terminal domain Mito_carr PF00153.22 CCC68743.1 - 3e-61 203.1 0.1 3.7e-21 74.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PilJ PF13675.1 CCC68745.1 - 0.34 11.2 9.7 5 7.4 0.5 4.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term PMC2NT PF08066.7 CCC68745.1 - 0.39 11.0 5.6 0.64 10.3 1.7 2.9 2 1 0 2 2 2 0 PMC2NT (NUC016) domain TPR_12 PF13424.1 CCC68745.1 - 0.4 10.6 5.1 8.7 6.3 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCC68745.1 - 2.6 8.8 6.6 11 6.8 0.1 3.7 3 2 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M1 PF01433.15 CCC68746.1 - 2.4e-83 280.4 1.2 2.4e-83 280.4 0.8 1.5 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 CCC68746.1 - 3.1e-38 131.8 0.0 6.1e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CCC68746.1 - 9.6e-14 51.5 0.0 1.8e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Tropomyosin_1 PF12718.2 CCC68747.1 - 1.3e-45 154.8 40.8 1.5e-45 154.5 28.3 1.1 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 CCC68747.1 - 8.1e-07 28.3 38.5 0.00017 20.7 11.5 2.1 1 1 1 2 2 2 2 Tropomyosin Laminin_II PF06009.7 CCC68747.1 - 4.6e-06 26.4 22.2 0.00046 19.9 8.2 2.1 1 1 1 2 2 2 2 Laminin Domain II KLRAQ PF10205.4 CCC68747.1 - 0.00017 21.5 25.5 0.00061 19.7 10.7 2.2 1 1 1 2 2 2 1 Predicted coiled-coil domain-containing protein CENP-F_leu_zip PF10473.4 CCC68747.1 - 0.00022 21.1 43.3 0.0003 20.6 5.8 2.8 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 CCC68747.1 - 0.0003 20.6 25.9 1.1 9.2 2.7 4.4 2 1 2 4 4 4 3 Flagella accessory protein C (FlaC) APG6 PF04111.7 CCC68747.1 - 0.0028 16.7 39.7 0.1 11.6 13.3 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 MbeD_MobD PF04899.7 CCC68747.1 - 0.0038 17.0 3.1 0.0038 17.0 2.1 2.7 2 1 1 3 3 3 1 MbeD/MobD like Mod_r PF07200.8 CCC68747.1 - 0.0038 17.1 29.9 0.013 15.4 16.9 2.3 1 1 1 2 2 2 1 Modifier of rudimentary (Mod(r)) protein BLOC1_2 PF10046.4 CCC68747.1 - 0.0041 17.2 28.9 0.014 15.4 6.6 3.2 1 1 2 3 3 3 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 ATG16 PF08614.6 CCC68747.1 - 0.005 16.6 13.5 0.005 16.6 9.3 2.1 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) GAS PF13851.1 CCC68747.1 - 0.01 15.0 36.1 1.2 8.2 23.6 2.4 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding WXG100 PF06013.7 CCC68747.1 - 0.012 15.6 12.1 0.16 11.9 0.6 3.8 1 1 2 3 3 3 0 Proteins of 100 residues with WXG Rootletin PF15035.1 CCC68747.1 - 0.013 15.4 31.6 0.16 11.9 21.4 2.3 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Myosin_tail_1 PF01576.14 CCC68747.1 - 0.019 12.6 38.0 0.025 12.3 26.3 1.2 1 0 0 1 1 1 0 Myosin tail Filament PF00038.16 CCC68747.1 - 0.033 13.6 29.8 0.2 11.0 9.3 2.0 1 1 1 2 2 2 0 Intermediate filament protein Reo_sigmaC PF04582.7 CCC68747.1 - 0.034 13.3 5.6 0.54 9.3 0.5 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 CCC68747.1 - 0.038 11.3 29.4 0.043 11.1 20.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_I PF06008.9 CCC68747.1 - 0.05 12.9 25.7 0.6 9.3 17.4 2.0 1 1 0 1 1 1 0 Laminin Domain I ERM PF00769.14 CCC68747.1 - 0.056 12.9 36.4 0.044 13.3 18.2 2.0 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DivIVA PF05103.8 CCC68747.1 - 0.062 13.3 29.6 0.75 9.8 3.3 3.1 1 1 2 3 3 3 0 DivIVA protein DUF972 PF06156.8 CCC68747.1 - 0.063 13.6 29.6 1.7 9.0 12.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IFT57 PF10498.4 CCC68747.1 - 0.11 11.1 30.3 0.83 8.3 14.0 2.1 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Phage_GP20 PF06810.6 CCC68747.1 - 0.13 11.7 34.1 0.28 10.5 8.9 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 EzrA PF06160.7 CCC68747.1 - 0.13 10.4 28.0 0.31 9.1 19.4 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA ADIP PF11559.3 CCC68747.1 - 0.14 12.0 30.9 0.47 10.3 9.2 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF720 PF05302.6 CCC68747.1 - 0.14 11.8 5.0 0.24 11.1 3.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF720) DUF3573 PF12097.3 CCC68747.1 - 0.17 10.4 7.9 0.25 9.9 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Metal_resist PF13801.1 CCC68747.1 - 0.18 11.7 1.7 4 7.4 0.1 2.1 2 0 0 2 2 2 0 Heavy-metal resistance GOLGA2L5 PF15070.1 CCC68747.1 - 0.2 10.1 26.0 0.26 9.7 18.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 CENP-K PF11802.3 CCC68747.1 - 0.21 10.7 27.0 0.011 15.0 5.7 2.1 1 1 1 2 2 2 0 Centromere-associated protein K DUF904 PF06005.7 CCC68747.1 - 0.23 11.7 45.0 18 5.6 2.5 3.9 2 1 0 2 2 1 0 Protein of unknown function (DUF904) IncA PF04156.9 CCC68747.1 - 0.27 10.8 39.0 0.71 9.4 12.1 2.0 1 1 1 2 2 2 0 IncA protein HisKA_3 PF07730.8 CCC68747.1 - 0.29 11.5 8.1 0.87 9.9 0.1 3.6 1 1 2 3 3 3 0 Histidine kinase DUF4407 PF14362.1 CCC68747.1 - 0.29 10.0 16.3 0.37 9.6 11.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4201 PF13870.1 CCC68747.1 - 0.4 10.0 31.4 2.4 7.5 21.8 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) TUDOR PF00567.19 CCC68747.1 - 0.41 10.5 3.8 2.3 8.0 0.0 2.7 1 1 2 3 3 3 0 Tudor domain Nup54 PF13874.1 CCC68747.1 - 0.41 10.3 19.6 1.2 8.7 9.6 2.2 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 Sec2p PF06428.6 CCC68747.1 - 0.41 10.5 33.0 0.057 13.2 11.8 3.2 1 1 1 3 3 3 0 GDP/GTP exchange factor Sec2p bZIP_1 PF00170.16 CCC68747.1 - 0.5 10.3 37.3 2.1 8.3 5.4 4.8 2 2 2 4 4 4 0 bZIP transcription factor Vps5 PF09325.5 CCC68747.1 - 0.54 9.4 25.7 0.64 9.2 2.3 3.6 1 1 3 4 4 4 0 Vps5 C terminal like Sec20 PF03908.8 CCC68747.1 - 0.55 9.9 11.6 3 7.5 0.1 2.8 1 1 2 3 3 3 0 Sec20 NPV_P10 PF05531.7 CCC68747.1 - 0.65 10.2 14.0 9.9 6.5 2.3 3.6 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF869 PF05911.6 CCC68747.1 - 0.68 8.0 32.4 0.91 7.6 13.8 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF3287 PF11690.3 CCC68747.1 - 0.79 9.8 11.0 0.18 11.8 1.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF3287) Lectin_N PF03954.9 CCC68747.1 - 0.84 9.0 10.7 0.97 8.8 1.8 2.3 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Mnd1 PF03962.10 CCC68747.1 - 0.91 9.1 32.4 1.6 8.3 11.4 2.1 1 1 1 2 2 2 0 Mnd1 family AAA_13 PF13166.1 CCC68747.1 - 0.95 7.8 29.5 2.6 6.4 9.6 1.6 1 1 0 1 1 1 0 AAA domain DUF1640 PF07798.6 CCC68747.1 - 0.97 9.4 23.8 1.6 8.7 16.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Hormone_1 PF00103.15 CCC68747.1 - 0.99 8.7 13.4 0.6 9.4 2.5 2.4 1 1 2 3 3 3 0 Somatotropin hormone family DUF3450 PF11932.3 CCC68747.1 - 1 8.5 25.8 0.82 8.8 8.6 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Cast PF10174.4 CCC68747.1 - 1.3 7.0 36.8 2.8 5.8 25.5 1.5 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone HOOK PF05622.7 CCC68747.1 - 1.3 6.7 29.3 1.5 6.5 20.3 1.1 1 0 0 1 1 1 0 HOOK protein DUF4200 PF13863.1 CCC68747.1 - 1.5 8.7 40.3 14 5.6 11.8 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) TBPIP PF07106.8 CCC68747.1 - 1.6 8.2 33.9 3.8 7.0 10.3 2.7 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 CCC68747.1 - 1.6 7.6 27.6 0.66 8.8 14.7 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Seryl_tRNA_N PF02403.17 CCC68747.1 - 1.9 8.5 34.0 3.4 7.7 11.1 3.3 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.3 CCC68747.1 - 1.9 8.3 46.3 0.083 12.7 12.8 3.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Katanin_con80 PF13925.1 CCC68747.1 - 1.9 8.1 12.1 0.33 10.6 1.6 2.7 1 1 2 3 3 3 0 con80 domain of Katanin HGD-D PF06050.8 CCC68747.1 - 2 7.1 6.1 1.3 7.7 3.2 1.5 1 1 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Synaptobrevin PF00957.16 CCC68747.1 - 2.3 7.8 17.6 0.059 12.9 1.0 2.9 1 1 2 3 3 3 0 Synaptobrevin Fzo_mitofusin PF04799.8 CCC68747.1 - 2.5 7.4 18.9 1.4 8.2 7.5 2.4 1 1 1 2 2 2 0 fzo-like conserved region Fib_alpha PF08702.5 CCC68747.1 - 2.5 8.1 19.5 4.5 7.3 5.6 2.6 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fez1 PF06818.10 CCC68747.1 - 3 7.8 27.9 4 7.4 19.3 1.2 1 0 0 1 1 1 0 Fez1 DUF812 PF05667.6 CCC68747.1 - 3.7 5.9 28.9 2.9 6.2 8.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Hemerythrin PF01814.18 CCC68747.1 - 3.7 7.7 11.5 12 6.0 0.5 3.3 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain KxDL PF10241.4 CCC68747.1 - 3.8 7.4 10.5 3.7 7.5 4.9 2.5 1 1 2 3 3 3 0 Uncharacterized conserved protein CENP-Q PF13094.1 CCC68747.1 - 4.2 7.3 32.8 0.27 11.2 17.5 2.0 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3391 PF11871.3 CCC68747.1 - 4.4 7.5 14.4 4.6 7.4 3.3 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF3391) DUF342 PF03961.8 CCC68747.1 - 4.7 5.5 31.3 0.94 7.8 9.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CCDC155 PF14662.1 CCC68747.1 - 4.9 6.7 36.7 2.8 7.4 18.8 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 HALZ PF02183.13 CCC68747.1 - 5.1 6.8 29.6 1.6 8.5 3.4 4.1 2 1 2 4 4 3 0 Homeobox associated leucine zipper DUF651 PF04895.7 CCC68747.1 - 5.4 6.6 11.4 6.5 6.4 0.2 3.1 1 1 2 3 3 3 0 Archaeal protein of unknown function (DUF651) NTP_transf_5 PF14907.1 CCC68747.1 - 6.2 6.0 10.1 3 7.0 0.6 3.0 2 1 1 3 3 3 0 Uncharacterised nucleotidyltransferase RmuC PF02646.11 CCC68747.1 - 6.3 5.5 19.9 3.3 6.4 5.5 2.8 1 1 2 3 3 3 0 RmuC family Spc24 PF08286.6 CCC68747.1 - 6.5 6.4 35.0 2.6 7.7 2.5 4.0 1 1 2 3 3 2 0 Spc24 subunit of Ndc80 CALCOCO1 PF07888.6 CCC68747.1 - 6.6 4.8 27.4 8.4 4.5 19.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2935 PF11155.3 CCC68747.1 - 6.9 6.7 16.3 2.4 8.2 3.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Syntaxin-6_N PF09177.6 CCC68747.1 - 7.5 7.0 23.8 9 6.7 4.9 3.2 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 CCC68747.1 - 8.9 6.1 18.7 3.5 7.4 3.3 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) AATF-Che1 PF13339.1 CCC68747.1 - 9.2 6.4 22.4 36 4.5 6.4 2.8 1 1 0 2 2 2 0 Apoptosis antagonizing transcription factor Prefoldin_2 PF01920.15 CCC68747.1 - 9.6 6.0 42.4 6.9 6.4 3.2 3.7 1 1 2 3 3 3 0 Prefoldin subunit FTO_CTD PF12934.2 CCC68747.1 - 10 5.6 13.3 3.3 7.2 3.1 2.2 1 1 1 2 2 2 0 FTO C-terminal domain HORMA PF02301.13 CCC68748.1 - 1.7e-19 70.1 1.5 2e-19 69.9 1.0 1.1 1 0 0 1 1 1 1 HORMA domain SKG6 PF08693.5 CCC68749.1 - 3e-13 48.8 0.2 1e-12 47.1 0.1 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain He_PIG PF05345.7 CCC68749.1 - 8.9e-08 32.0 17.4 0.00023 21.1 0.0 5.1 5 0 0 5 5 4 2 Putative Ig domain Mid2 PF04478.7 CCC68749.1 - 0.00014 21.2 2.5 0.00048 19.5 1.8 2.0 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor DUF4448 PF14610.1 CCC68749.1 - 0.00021 20.8 0.7 0.00075 19.0 0.5 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 CCC68749.1 - 0.0016 18.1 1.9 0.0049 16.5 1.3 1.8 1 0 0 1 1 1 1 TMEM154 protein family Pox_A14 PF05767.7 CCC68749.1 - 0.0097 15.8 0.0 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 Adeno_E3_CR2 PF02439.10 CCC68749.1 - 0.013 15.0 0.1 0.024 14.1 0.1 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1180 PF06679.7 CCC68749.1 - 0.024 14.5 0.9 0.049 13.5 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Rifin_STEVOR PF02009.11 CCC68749.1 - 0.042 13.4 1.4 0.074 12.6 1.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 CCC68749.1 - 0.11 12.8 0.0 0.63 10.4 0.0 2.3 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Peptidase_M56 PF05569.6 CCC68749.1 - 0.21 10.5 0.3 0.38 9.6 0.2 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 Podoplanin PF05808.6 CCC68749.1 - 6.6 6.2 10.2 1 8.9 2.7 2.2 2 0 0 2 2 2 0 Podoplanin EF-hand_4 PF12763.2 CCC68750.1 - 1.7e-48 162.6 5.7 6.5e-48 160.7 2.0 2.7 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand End3 PF12761.2 CCC68750.1 - 8.2e-33 113.6 8.0 2.1e-32 112.3 5.5 1.7 1 1 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_1 PF00036.27 CCC68750.1 - 0.0035 16.5 1.9 0.0083 15.3 1.3 1.7 1 0 0 1 1 1 1 EF hand FlaC_arch PF05377.6 CCC68750.1 - 0.004 17.0 8.3 0.019 14.8 0.5 3.0 3 0 0 3 3 2 1 Flagella accessory protein C (FlaC) NPV_P10 PF05531.7 CCC68750.1 - 0.027 14.6 9.7 0.46 10.7 0.1 3.5 3 1 0 4 4 3 0 Nucleopolyhedrovirus P10 protein EF-hand_8 PF13833.1 CCC68750.1 - 0.03 13.9 0.9 0.063 12.9 0.6 1.6 1 0 0 1 1 1 0 EF-hand domain pair vATP-synt_E PF01991.13 CCC68750.1 - 0.087 12.0 6.2 0.19 11.0 4.3 1.5 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit EMP24_GP25L PF01105.19 CCC68750.1 - 0.14 11.8 1.7 9.9 5.8 0.0 2.4 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD KSR1-SAM PF13543.1 CCC68750.1 - 0.22 11.3 2.5 4 7.2 1.7 2.4 1 1 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 IncA PF04156.9 CCC68750.1 - 0.4 10.2 11.0 20 4.7 7.8 2.3 1 1 0 1 1 1 0 IncA protein TcdB_N PF12918.2 CCC68750.1 - 0.41 10.7 6.4 0.48 10.5 1.8 2.7 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Spc24 PF08286.6 CCC68750.1 - 0.84 9.3 10.3 1 9.0 0.7 2.8 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Adeno_PIX PF03955.9 CCC68750.1 - 2 8.9 6.1 8.9 6.8 0.9 2.3 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Erp_C PF06780.6 CCC68750.1 - 2.4 7.9 12.9 0.1 12.4 0.7 3.4 2 1 2 4 4 4 0 Erp protein C-terminus Allexi_40kDa PF05549.6 CCC68750.1 - 3.1 7.0 9.9 1.4 8.1 3.4 2.1 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF948 PF06103.6 CCC68750.1 - 3.4 7.6 5.5 1.3 8.9 0.5 2.4 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 CCC68750.1 - 3.5 6.7 8.9 7.3 5.6 0.2 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3450 PF11932.3 CCC68750.1 - 3.7 6.7 14.8 0.14 11.4 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) ATG16 PF08614.6 CCC68750.1 - 6.2 6.5 17.7 21 4.8 10.3 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.7 CCC68750.1 - 9.2 6.0 9.6 7.3 6.4 4.6 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Sugarporin_N PF11471.3 CCC68750.1 - 9.9 5.8 10.8 0.077 12.6 1.2 2.2 3 0 0 3 3 2 0 Maltoporin periplasmic N-terminal extension Cpn60_TCP1 PF00118.19 CCC68751.1 - 5.3e-139 463.9 11.5 6.3e-139 463.7 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Transposase_23 PF03017.9 CCC68751.1 - 0.019 14.4 0.2 0.11 11.9 0.0 2.2 2 0 0 2 2 2 0 TNP1/EN/SPM transposase MKT1_C PF12246.3 CCC68752.1 - 6.8e-63 211.8 6.5 1.2e-62 211.1 4.5 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 CCC68752.1 - 7.9e-31 106.2 0.4 3e-30 104.3 0.0 2.3 2 0 0 2 2 2 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 CCC68752.1 - 2.2e-20 72.8 0.0 5.7e-20 71.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCC68752.1 - 2.2e-09 37.2 0.0 5.4e-09 36.0 0.0 1.7 1 0 0 1 1 1 1 XPG I-region OST3_OST6 PF04756.8 CCC68753.1 - 4.6e-27 94.5 11.0 1e-26 93.4 7.6 1.6 1 0 0 1 1 1 1 OST3 / OST6 family Thioredoxin PF00085.15 CCC68753.1 - 0.0022 17.6 0.0 0.0051 16.4 0.0 1.6 1 1 0 1 1 1 1 Thioredoxin MFS_1 PF07690.11 CCC68753.1 - 0.055 12.1 7.9 0.13 10.9 5.5 1.6 1 1 0 1 1 1 0 Major Facilitator Superfamily Voltage_CLC PF00654.15 CCC68753.1 - 0.14 11.1 5.7 0.13 11.2 2.6 1.8 1 1 0 1 1 1 0 Voltage gated chloride channel C2 PF00168.25 CCC68754.1 - 4e-55 183.6 5.6 7.9e-19 67.2 0.0 4.5 4 0 0 4 4 4 4 C2 domain Ni_hydr_CYTB PF01292.15 CCC68754.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 Ion_trans PF00520.26 CCC68755.1 - 0.012 14.8 25.5 0.011 15.0 15.3 2.5 2 1 0 2 2 2 0 Ion transport protein PKD_channel PF08016.7 CCC68755.1 - 0.038 12.4 18.2 0.074 11.4 10.1 2.7 2 1 0 2 2 2 0 Polycystin cation channel DUF2116 PF09889.4 CCC68755.1 - 1.4 8.7 4.5 7.1 6.5 0.0 3.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ras PF00071.17 CCC68756.1 - 9.6e-60 200.6 0.1 1.2e-59 200.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC68756.1 - 9e-20 71.3 0.0 1.6e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC68756.1 - 1.6e-17 63.2 0.1 1.9e-17 63.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCC68756.1 - 3.7e-09 36.0 0.0 4.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCC68756.1 - 3.6e-06 26.5 0.0 6.6e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCC68756.1 - 8.8e-06 25.6 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PP2C PF00481.16 CCC68757.1 - 1.2e-45 155.8 0.0 3.4e-45 154.4 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Mem_trans PF03547.13 CCC68758.1 - 4.4e-87 291.8 0.0 7.8e-87 291.0 0.0 1.4 1 1 0 1 1 1 1 Membrane transport protein KdpC PF02669.10 CCC68758.1 - 0.035 13.8 3.5 0.11 12.1 0.4 2.4 1 1 1 2 2 2 0 K+-transporting ATPase, c chain DUF966 PF06136.8 CCC68758.1 - 2.8 7.2 10.3 3.9 6.8 7.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) AMP-binding PF00501.23 CCC68759.1 - 2.2e-31 108.6 0.0 3.3e-18 65.2 0.0 4.9 4 1 0 4 4 4 4 AMP-binding enzyme DMAP_binding PF06464.6 CCC68759.1 - 2.7e-12 47.2 0.2 2.7e-12 47.2 0.2 2.4 2 0 0 2 2 2 1 DMAP1-binding Domain OHA PF14418.1 CCC68759.1 - 0.026 14.0 0.2 0.12 11.8 0.2 2.2 1 0 0 1 1 1 0 OST-HTH Associated domain Arf PF00025.16 CCC68760.1 - 1.7e-71 239.0 0.4 2e-71 238.7 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCC68760.1 - 8.9e-16 57.6 0.1 1.1e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 CCC68760.1 - 6.2e-14 51.7 0.0 7.3e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 CCC68760.1 - 4.7e-13 48.5 1.4 2.8e-09 36.1 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCC68760.1 - 8.2e-11 41.4 0.0 9.5e-11 41.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCC68760.1 - 1.1e-10 42.0 0.0 1.5e-10 41.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCC68760.1 - 9.5e-07 28.7 0.1 1.2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 CCC68760.1 - 0.1 11.6 0.2 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase Rib_5-P_isom_A PF06026.9 CCC68761.1 - 9.8e-57 191.0 0.1 1.2e-56 190.7 0.1 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 CCC68761.1 - 0.0019 17.8 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 2 DeoR C terminal sensor domain Ribosomal_S7e PF01251.13 CCC68762.1 - 1.5e-80 269.1 3.0 1.8e-80 268.9 2.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e HMA PF00403.21 CCC68762.1 - 0.11 12.6 0.2 17 5.6 0.0 2.7 3 0 0 3 3 3 0 Heavy-metal-associated domain DUF2951 PF11166.3 CCC68763.1 - 0.052 13.4 0.5 0.13 12.0 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Acyltransferase PF01553.16 CCC68765.1 - 1.1e-09 37.8 0.0 6.7e-09 35.2 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Formyl_trans_N PF00551.14 CCC68766.1 - 1.8e-28 99.3 0.0 2.8e-28 98.6 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 CCC68766.1 - 6.3e-07 29.4 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Glyco_transf_15 PF01793.11 CCC68767.1 - 3.4e-144 479.8 11.9 4.1e-144 479.5 8.2 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Mito_carr PF00153.22 CCC68768.1 - 2.7e-60 200.0 4.9 2.1e-20 72.1 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein GTP1_OBG PF01018.17 CCC68768.1 - 0.024 14.2 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 GTP1/OBG Ras PF00071.17 CCC68769.1 - 2.3e-56 189.6 0.2 4.1e-56 188.8 0.2 1.4 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC68769.1 - 8.1e-20 71.5 0.7 2.5e-19 69.8 0.1 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCC68769.1 - 1.7e-08 33.8 0.1 2.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCC68769.1 - 4.8e-05 23.2 0.8 8.4e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCC68769.1 - 5.4e-05 22.6 1.4 0.00018 20.9 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 CCC68769.1 - 0.076 12.4 0.1 0.16 11.3 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCC68769.1 - 0.12 11.6 1.3 0.26 10.4 0.1 2.1 2 2 0 2 2 2 0 Protein of unknown function, DUF258 SNARE PF05739.14 CCC68771.1 - 5.4e-15 54.8 6.6 5.4e-15 54.8 4.6 1.8 2 0 0 2 2 1 1 SNARE domain Synaptobrevin PF00957.16 CCC68771.1 - 7.8e-05 22.2 1.7 7.8e-05 22.2 1.2 2.1 3 0 0 3 3 3 1 Synaptobrevin TMPIT PF07851.8 CCC68771.1 - 0.00022 20.4 5.0 0.00029 20.0 3.5 1.2 1 0 0 1 1 1 1 TMPIT-like protein MCPsignal PF00015.16 CCC68771.1 - 0.008 15.7 7.7 0.012 15.1 5.3 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Herpes_US9 PF06072.6 CCC68771.1 - 0.016 15.0 0.4 0.032 14.0 0.3 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF912 PF06024.7 CCC68771.1 - 0.064 13.3 0.4 0.064 13.3 0.3 2.5 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EIIBC-GUT_N PF03612.9 CCC68771.1 - 0.2 11.2 4.0 0.44 10.1 2.8 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Phostensin_N PF13916.1 CCC68771.1 - 0.22 11.4 6.1 0.07 13.1 1.4 2.3 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF3708 PF12501.3 CCC68771.1 - 2 8.2 4.1 0.79 9.5 0.4 1.9 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter DUF4519 PF15012.1 CCC68771.1 - 2.3 8.1 0.0 2.2 8.2 0.1 3.3 4 0 0 4 4 3 0 Domain of unknown function (DUF4519) TPR_MLP1_2 PF07926.7 CCC68771.1 - 6.4 6.5 20.2 5.7 6.6 12.8 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein OppC_N PF12911.2 CCC68771.1 - 6.4 6.2 7.7 0.39 10.1 1.5 1.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF2116 PF09889.4 CCC68771.1 - 9.9 6.0 8.8 0.55 10.0 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PspB PF06667.7 CCC68772.1 - 0.15 11.9 0.9 0.49 10.3 0.6 1.8 1 0 0 1 1 1 0 Phage shock protein B bZIP_2 PF07716.10 CCC68772.1 - 2.5 7.9 13.5 0.024 14.4 2.9 2.6 3 0 0 3 3 3 0 Basic region leucine zipper Syntaxin PF00804.20 CCC68772.1 - 5.8 7.1 12.7 1.3e+02 2.8 8.8 2.9 1 1 0 1 1 1 0 Syntaxin RGS PF00615.14 CCC68773.1 - 3.4e-09 36.8 1.4 3.4e-09 36.8 0.9 2.0 2 1 0 2 2 2 1 Regulator of G protein signaling domain HMGL-like PF00682.14 CCC68774.1 - 5.4e-75 252.0 0.0 8.9e-75 251.3 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 CCC68774.1 - 6.8e-29 100.3 1.7 2.1e-28 98.7 1.2 1.9 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Syja_N PF02383.13 CCC68775.1 - 8.2e-92 307.3 0.1 1.1e-91 306.9 0.1 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CCC68775.1 - 3.2e-27 96.0 0.0 5.5e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YEATS PF03366.11 CCC68776.1 - 1.1e-34 118.0 1.5 1.6e-34 117.4 1.1 1.3 1 0 0 1 1 1 1 YEATS family Osmo_CC PF08946.5 CCC68776.1 - 0.22 11.5 2.6 0.54 10.3 1.8 1.6 1 0 0 1 1 1 0 Osmosensory transporter coiled coil His_Phos_1 PF00300.17 CCC68777.1 - 2e-22 79.9 0.0 7.4e-22 78.1 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) TFIIIC_sub6 PF10419.4 CCC68777.1 - 1.6e-15 56.2 0.5 6.1e-15 54.3 0.0 2.2 2 0 0 2 2 2 1 TFIIIC subunit UL73_N PF12522.3 CCC68777.1 - 0.54 9.8 3.3 1.3 8.5 2.3 1.6 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal Maf PF02545.9 CCC68778.1 - 2.3e-51 173.6 0.0 2.8e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein HEAT PF02985.17 CCC68779.1 - 0.00019 21.2 0.1 1.6 9.0 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat CLASP_N PF12348.3 CCC68779.1 - 0.01 15.2 0.2 1.3 8.3 0.0 2.7 2 1 1 3 3 3 0 CLASP N terminal Vac14_Fab1_bd PF12755.2 CCC68779.1 - 0.025 14.9 0.2 22 5.4 0.0 3.3 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 CCC68779.1 - 0.053 13.8 0.0 0.95 9.7 0.0 2.5 1 1 1 2 2 2 0 HEAT repeats HEAT_EZ PF13513.1 CCC68779.1 - 0.11 13.0 0.2 1.4e+02 3.1 0.0 4.2 3 1 0 3 3 3 0 HEAT-like repeat zf-H2C2_2 PF13465.1 CCC68780.1 - 2.6e-23 81.1 24.1 1.2e-09 37.9 1.1 4.5 4 0 0 4 4 4 4 Zinc-finger double domain zf-C2H2 PF00096.21 CCC68780.1 - 1.2e-20 72.5 26.1 4.7e-06 26.6 0.5 4.7 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC68780.1 - 2e-15 55.9 23.7 0.00028 21.0 0.3 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-met PF12874.2 CCC68780.1 - 0.00014 21.9 14.7 0.00053 20.0 0.2 4.8 4 1 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCC68780.1 - 0.00026 21.0 13.3 0.03 14.4 0.1 4.3 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 CCC68780.1 - 0.00052 20.0 5.4 0.015 15.4 0.2 2.6 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 CCC68780.1 - 0.0022 17.8 19.1 0.0069 16.2 0.7 4.2 4 0 0 4 4 4 2 C2H2-type zinc finger zf-CHCC PF10276.4 CCC68780.1 - 0.0036 17.1 9.1 0.34 10.7 0.6 3.3 3 0 0 3 3 3 2 Zinc-finger domain zf-BED PF02892.10 CCC68780.1 - 0.056 13.2 14.8 1.5 8.6 0.3 3.7 2 1 1 3 3 3 0 BED zinc finger zf-C2HC_2 PF13913.1 CCC68780.1 - 0.57 9.9 10.5 1.2 8.9 0.1 4.2 4 0 0 4 4 4 0 zinc-finger of a C2HC-type TSGP1 PF07771.6 CCC68780.1 - 9.9 6.0 10.0 0.47 10.3 1.7 2.7 2 0 0 2 2 2 0 Tick salivary peptide group 1 TRAPP PF04051.11 CCC68781.1 - 5.9e-33 113.5 0.2 1.2e-32 112.5 0.2 1.5 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component SH3_9 PF14604.1 CCC68782.1 - 2.5e-26 90.9 0.1 1.7e-14 53.1 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 CCC68782.1 - 2.5e-24 84.4 0.1 3.4e-11 42.3 0.0 2.5 2 0 0 2 2 2 2 SH3 domain FCH PF00611.18 CCC68782.1 - 1.3e-23 82.9 0.2 1.3e-23 82.9 0.1 2.7 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_2 PF07653.12 CCC68782.1 - 5.2e-13 48.2 0.0 3e-08 33.0 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain DUF948 PF06103.6 CCC68782.1 - 1.2 9.0 4.7 5.3 6.9 0.2 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) FHA PF00498.21 CCC68783.1 - 1.7e-11 44.0 0.0 4e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CCC68783.1 - 1.1e-06 28.3 6.1 2.5e-06 27.2 4.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCC68783.1 - 0.0003 20.7 8.0 0.0007 19.5 5.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 CCC68783.1 - 0.0008 19.4 1.7 0.0019 18.2 1.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CCC68783.1 - 0.0021 17.6 6.6 0.0055 16.3 4.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC68783.1 - 0.0063 16.2 6.0 0.016 14.9 4.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 CCC68783.1 - 0.015 15.1 3.0 0.05 13.4 2.1 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 CCC68783.1 - 0.037 13.7 7.2 0.044 13.4 3.1 2.5 2 0 0 2 2 2 0 PHD-finger zf-RING-like PF08746.6 CCC68783.1 - 0.13 12.3 5.8 0.13 12.2 2.3 2.3 2 0 0 2 2 2 0 RING-like domain zf-RING_4 PF14570.1 CCC68783.1 - 0.31 10.6 4.5 0.73 9.4 3.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CHCH PF06747.8 CCC68784.1 - 1.2e-05 25.0 4.9 2.4e-05 24.0 3.4 1.6 1 1 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 CCC68784.1 - 0.00041 20.4 6.2 0.00057 19.9 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) UPF0203 PF05254.7 CCC68784.1 - 0.07 12.9 8.2 0.19 11.5 1.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Toxin_17 PF08086.6 CCC68784.1 - 1.7 8.8 7.6 1.4 9.0 0.3 2.4 2 0 0 2 2 2 0 Ergtoxin family TPR_11 PF13414.1 CCC68785.1 - 1e-35 121.1 21.8 2.4e-12 46.3 0.2 6.9 4 2 2 7 7 7 6 TPR repeat TPR_2 PF07719.12 CCC68785.1 - 1.5e-25 87.0 25.7 9.5e-05 22.0 0.0 10.7 10 1 1 11 11 11 7 Tetratricopeptide repeat TPR_1 PF00515.23 CCC68785.1 - 4.6e-23 79.8 26.8 1.9e-05 24.0 1.3 9.6 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.1 CCC68785.1 - 1.1e-18 67.3 7.0 0.00013 22.4 0.0 5.9 5 1 1 6 6 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCC68785.1 - 1.8e-17 62.0 9.3 0.00076 19.4 0.0 8.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 CCC68785.1 - 2.2e-17 61.4 26.5 0.00034 20.1 0.0 9.1 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.1 CCC68785.1 - 6.5e-16 58.0 13.9 2.6e-05 24.0 0.0 6.6 2 2 4 7 7 7 6 Tetratricopeptide repeat TPR_19 PF14559.1 CCC68785.1 - 1.3e-14 54.2 13.2 0.0055 17.0 0.7 5.8 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCC68785.1 - 3.6e-14 51.9 4.7 0.49 11.1 0.0 8.4 4 3 5 9 9 8 3 Tetratricopeptide repeat Apc3 PF12895.2 CCC68785.1 - 6e-11 42.3 13.6 0.0043 17.1 1.0 4.9 4 1 1 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CCC68785.1 - 1.4e-05 24.8 0.0 0.66 9.8 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat NARP1 PF12569.3 CCC68785.1 - 0.00049 18.9 14.4 0.046 12.4 0.1 3.8 2 2 1 4 4 4 2 NMDA receptor-regulated protein 1 SPO22 PF08631.5 CCC68785.1 - 0.0012 17.9 2.3 0.048 12.7 0.1 3.2 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like DUF3808 PF10300.4 CCC68785.1 - 0.0047 15.5 6.2 0.14 10.7 0.0 3.2 2 1 2 4 4 4 2 Protein of unknown function (DUF3808) TPR_6 PF13174.1 CCC68785.1 - 0.017 15.5 20.1 9.5 6.9 0.1 8.2 9 0 0 9 9 8 0 Tetratricopeptide repeat RPN7 PF10602.4 CCC68785.1 - 0.028 13.8 2.5 0.3 10.4 0.1 3.3 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_7 PF13176.1 CCC68785.1 - 0.13 12.1 16.3 4.2 7.3 0.0 6.6 9 0 0 9 9 6 0 Tetratricopeptide repeat Sel1 PF08238.7 CCC68785.1 - 0.15 12.7 6.9 20 5.9 0.0 5.3 6 0 0 6 6 5 0 Sel1 repeat Fis1_TPR_C PF14853.1 CCC68785.1 - 0.82 9.5 6.5 20 5.1 0.0 4.3 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat ORC6 PF05460.8 CCC68786.1 - 5.2e-90 302.0 1.1 6.2e-90 301.8 0.7 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) N-SET PF11764.3 CCC68787.1 - 1e-38 132.8 1.9 3.2e-38 131.2 1.3 1.8 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component N SET PF00856.23 CCC68787.1 - 6.4e-23 81.8 4.3 7.7e-23 81.5 0.1 3.1 3 1 0 3 3 3 1 SET domain SET_assoc PF11767.3 CCC68787.1 - 5e-18 64.1 0.3 1.2e-17 62.9 0.2 1.7 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated MutS_V PF00488.16 CCC68788.1 - 6.3e-77 258.1 0.0 1.1e-76 257.3 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCC68788.1 - 7.6e-35 120.5 2.7 1.8e-34 119.3 1.9 1.7 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 CCC68788.1 - 3.8e-24 84.8 0.0 1e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 CCC68788.1 - 4e-10 39.8 0.0 4e-10 39.8 0.0 2.3 3 0 0 3 3 3 1 MutS domain II Urm1 PF09138.6 CCC68788.1 - 0.03 14.4 1.7 2.1 8.5 0.0 3.5 3 0 0 3 3 3 0 Urm1 (Ubiquitin related modifier) ComX PF05952.7 CCC68788.1 - 0.034 13.6 0.5 0.14 11.7 0.1 2.3 2 0 0 2 2 2 0 Bacillus competence pheromone ComX DUF59 PF01883.14 CCC68789.1 - 9.4e-05 22.3 0.0 0.00024 21.0 0.0 1.7 1 1 1 2 2 2 1 Domain of unknown function DUF59 CDP-OH_P_transf PF01066.16 CCC68790.1 - 2.1e-16 60.0 2.0 2.1e-16 60.0 1.4 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase NDT80_PhoG PF05224.7 CCC68791.1 - 4.8e-59 199.4 0.5 4.8e-59 199.4 0.3 2.0 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family DUF3605 PF12239.3 CCC68792.1 - 1.1e-34 119.6 2.7 1.8e-33 115.6 1.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) RRM_6 PF14259.1 CCC68793.1 - 0.019 14.9 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) CAP_GLY PF01302.20 CCC68794.1 - 1.5e-18 66.1 0.3 2.4e-18 65.5 0.2 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 CCC68794.1 - 2e-08 34.3 0.1 4.7e-08 33.1 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain ORC2 PF04084.9 CCC68794.1 - 0.021 13.6 0.5 0.029 13.2 0.3 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 2 Aegerolysin PF06355.8 CCC68794.1 - 0.16 11.8 1.6 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Aegerolysin LSM PF01423.17 CCC68795.1 - 1.3e-12 47.0 0.0 1.7e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain UPRTase PF14681.1 CCC68796.1 - 2.1e-76 255.7 0.0 2.6e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 CCC68796.1 - 0.0028 17.3 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 CCC68796.1 - 0.063 13.0 0.1 0.1 12.3 0.1 1.3 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Actin PF00022.14 CCC68797.1 - 1.8e-114 382.2 0.0 2.4e-114 381.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCC68797.1 - 0.11 11.1 0.0 7.4 5.0 0.0 2.5 2 1 0 2 2 2 0 MreB/Mbl protein PH_9 PF15410.1 CCC68799.1 - 0.15 12.1 1.5 0.58 10.3 1.0 1.9 1 1 0 1 1 1 0 Pleckstrin homology domain CENP-B_dimeris PF09026.5 CCC68799.1 - 4.7 7.5 13.5 13 6.1 9.3 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Peptidase_M14 PF00246.19 CCC68800.1 - 5.5e-67 226.3 0.1 1.1e-66 225.3 0.0 1.5 2 0 0 2 2 2 1 Zinc carboxypeptidase Endosulfine PF04667.12 CCC68801.1 - 4.4e-32 109.8 0.3 6.5e-32 109.3 0.2 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF4570 PF15134.1 CCC68801.1 - 0.097 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) INSIG PF07281.7 CCC68802.1 - 1.4e-10 40.8 0.8 2.5e-10 40.0 0.6 1.4 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) WLM PF08325.5 CCC68803.1 - 1.1e-54 185.1 0.0 1.4e-54 184.7 0.0 1.1 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.12 CCC68803.1 - 0.025 14.3 0.1 0.051 13.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF45 Pkinase PF00069.20 CCC68804.1 - 3.6e-34 118.0 0.0 8.1e-34 116.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68804.1 - 6.7e-13 48.2 0.0 1.4e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 CCC68804.1 - 0.78 8.4 3.7 1.2 7.8 0.0 2.1 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase RNA_pol_3_Rpc31 PF11705.3 CCC68805.1 - 0.0086 16.0 4.1 0.011 15.6 2.8 1.1 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Aminotran_1_2 PF00155.16 CCC68806.1 - 1.3e-18 67.0 0.0 2.3e-18 66.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3860 PF12976.2 CCC68806.1 - 0.057 13.2 0.0 0.23 11.2 0.0 2.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3860) DUF711 PF05167.7 CCC68806.1 - 0.059 12.0 0.1 0.1 11.3 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) DegT_DnrJ_EryC1 PF01041.12 CCC68806.1 - 0.073 12.0 0.2 0.37 9.7 0.1 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CCC68806.1 - 0.19 10.8 0.0 0.35 9.9 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Inhibitor_I9 PF05922.11 CCC68807.1 - 0.0074 16.8 0.1 0.065 13.8 0.1 2.1 1 1 0 1 1 1 1 Peptidase inhibitor I9 DUF2365 PF10157.4 CCC68807.1 - 0.013 15.3 0.1 0.015 15.1 0.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) CagZ PF09053.5 CCC68807.1 - 0.039 13.2 0.1 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 CagZ UBN2_2 PF14227.1 CCC68807.1 - 0.089 12.3 0.5 0.11 12.0 0.3 1.3 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type RRM_1 PF00076.17 CCC68808.1 - 6.8e-41 137.7 10.0 5.1e-16 58.0 0.1 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC68808.1 - 2.5e-29 101.0 5.6 2.3e-09 37.1 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC68808.1 - 7.3e-25 86.5 7.2 3.3e-08 33.2 0.4 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCC68808.1 - 7.3e-07 28.8 1.8 0.019 14.6 0.1 3.4 3 1 1 4 4 4 2 Limkain b1 Nup35_RRM_2 PF14605.1 CCC68808.1 - 3.1e-06 26.8 1.0 0.0088 15.7 0.0 3.6 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CCC68808.1 - 3.8e-06 26.6 4.3 0.093 12.5 0.2 4.2 4 0 0 4 4 4 2 RNA binding motif DUF500 PF04366.7 CCC68809.1 - 2.8e-44 149.6 0.1 4.8e-44 148.8 0.1 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 CCC68809.1 - 3.5e-17 61.4 0.0 6.5e-17 60.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCC68809.1 - 2.8e-14 52.4 0.1 5.1e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCC68809.1 - 9.7e-13 47.3 0.0 1.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PHP PF02811.14 CCC68810.1 - 1.2e-20 74.0 0.7 3.3e-20 72.6 0.5 1.7 1 1 0 1 1 1 1 PHP domain Acetyltransf_13 PF13880.1 CCC68811.1 - 1.7e-21 75.7 0.1 3.5e-21 74.7 0.0 1.5 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 CCC68811.1 - 9e-11 41.1 0.4 1.5e-10 40.4 0.2 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 CCC68811.1 - 0.0059 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCC68811.1 - 0.061 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DSPn PF14671.1 CCC68812.1 - 6.2e-50 168.8 0.1 1.9e-49 167.2 0.1 1.8 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 CCC68812.1 - 2.7e-24 85.2 0.0 1.9e-22 79.2 0.0 2.6 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCC68812.1 - 7.4e-05 22.2 0.0 0.00013 21.4 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 CCC68812.1 - 0.00075 18.9 0.6 0.0026 17.2 0.1 1.9 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 CCC68812.1 - 0.0054 16.7 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CCC68812.1 - 0.16 12.2 1.5 0.45 10.7 0.2 2.1 2 1 0 2 2 2 0 Tyrosine phosphatase family WD40 PF00400.27 CCC68813.1 - 0.061 13.2 1.4 1.1 9.2 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat COMPASS-Shg1 PF05205.7 CCC68814.1 - 7e-21 74.5 2.8 8.9e-21 74.1 1.9 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 HTH_27 PF13463.1 CCC68815.1 - 0.044 14.1 0.0 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 Winged helix DNA-binding domain RhoGAP PF00620.22 CCC68816.1 - 7.1e-42 142.5 0.4 2.5e-40 137.5 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 CCC68816.1 - 8.7e-15 54.6 7.3 2e-14 53.5 0.5 2.6 1 1 1 2 2 2 2 Fes/CIP4, and EFC/F-BAR homology domain ACPS PF01648.15 CCC68816.1 - 0.13 12.0 0.3 0.35 10.7 0.2 1.7 1 0 0 1 1 1 0 4'-phosphopantetheinyl transferase superfamily Methyltransf_PK PF05891.7 CCC68817.1 - 1.1e-91 306.0 0.0 1.2e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 CCC68817.1 - 3.7e-06 26.7 0.0 7e-06 25.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC68817.1 - 0.0005 20.6 0.0 0.00084 19.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 CCC68817.1 - 0.0031 16.7 0.1 0.0093 15.1 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_11 PF08241.7 CCC68817.1 - 0.0056 17.1 0.0 0.015 15.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC68817.1 - 0.029 14.7 0.0 0.068 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain MSC PF09402.5 CCC68818.1 - 0.01 14.5 0.8 0.011 14.4 0.6 1.0 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain COX7a PF02238.10 CCC68818.1 - 0.023 14.4 0.6 0.045 13.4 0.1 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIa PolyA_pol_arg_C PF12626.2 CCC68818.1 - 0.072 12.7 0.2 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 Polymerase A arginine-rich C-terminus DUF607 PF04678.8 CCC68818.1 - 0.092 12.6 0.4 0.13 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 SHMT PF00464.14 CCC68819.1 - 1.5e-204 678.8 0.0 1.8e-204 678.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CCC68819.1 - 0.16 11.0 0.0 0.31 10.1 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Ras PF00071.17 CCC68820.1 - 1.3e-45 154.6 0.1 1.8e-45 154.2 0.1 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC68820.1 - 2.5e-18 66.6 0.0 4.9e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC68820.1 - 1e-16 60.6 0.1 1.5e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCC68820.1 - 3.5e-07 29.6 0.0 4.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCC68820.1 - 2.1e-05 24.4 0.1 4.7e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCC68820.1 - 6.9e-05 22.1 0.0 0.00013 21.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCC68820.1 - 0.0024 16.6 0.4 0.45 9.1 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit AAA_14 PF13173.1 CCC68820.1 - 0.0068 16.2 0.4 0.021 14.7 0.3 1.7 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.22 CCC68820.1 - 0.0085 15.5 0.0 0.23 10.8 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CCC68820.1 - 0.062 12.4 0.0 0.74 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Rif1_N PF12231.3 CCC68821.1 - 1e-38 133.2 11.1 2.4e-38 132.0 7.7 1.6 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Pkinase PF00069.20 CCC68822.1 - 4.7e-60 202.9 0.0 6.7e-60 202.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68822.1 - 2.3e-34 118.6 0.0 3.1e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC68822.1 - 4.1e-09 35.8 0.0 6.9e-09 35.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CCC68822.1 - 0.00036 19.4 0.1 0.0047 15.7 0.0 2.1 2 0 0 2 2 2 1 Seadornavirus VP7 Choline_kinase PF01633.15 CCC68822.1 - 0.019 14.5 0.0 0.065 12.8 0.0 1.8 2 0 0 2 2 2 0 Choline/ethanolamine kinase Kdo PF06293.9 CCC68822.1 - 0.021 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UBX PF00789.15 CCC68823.1 - 1.2e-16 60.5 0.0 2.5e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 UBX domain SID-1_RNA_chan PF13965.1 CCC68823.1 - 0.14 10.2 2.9 0.35 8.9 0.2 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 Methyltransf_16 PF10294.4 CCC68825.1 - 2e-25 89.2 0.0 3e-25 88.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 CCC68825.1 - 4.4e-09 36.1 0.0 8.7e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC68825.1 - 8.7e-08 32.0 0.0 1.8e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC68825.1 - 2e-06 28.3 0.0 5.1e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCC68825.1 - 0.00055 19.3 0.0 0.001 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 CCC68825.1 - 0.00082 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCC68825.1 - 0.00091 19.6 0.0 0.0024 18.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 CCC68825.1 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.7 CCC68825.1 - 0.0015 18.9 0.0 0.0038 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain HbrB PF08539.6 CCC68826.1 - 2.8e-41 140.9 1.1 5.6e-41 140.0 0.8 1.5 1 0 0 1 1 1 1 HbrB-like DAP PF15228.1 CCC68826.1 - 0.1 13.3 1.0 0.43 11.3 0.9 1.9 2 0 0 2 2 2 0 Death-associated protein DUF1674 PF07896.7 CCC68827.1 - 3.3e-16 59.2 2.6 5e-16 58.6 1.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) Vma12 PF11712.3 CCC68827.1 - 0.2 11.3 0.8 0.23 11.1 0.5 1.1 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Ribosomal_L37 PF08561.5 CCC68828.1 - 1.5e-27 94.9 3.4 1.9e-27 94.6 2.4 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 zf-C2H2_2 PF12756.2 CCC68829.1 - 3.4e-35 120.1 6.6 9.7e-32 109.0 1.6 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CCC68829.1 - 0.011 15.9 4.8 0.059 13.5 0.7 2.9 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CCC68829.1 - 0.93 9.9 8.2 5 7.6 0.4 3.3 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 CCC68829.1 - 2.7 8.5 11.5 0.67 10.4 0.7 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF3505 PF12013.3 CCC68829.1 - 3 8.1 6.0 80 3.5 0.6 3.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3505) AKAP95 PF04988.7 CCC68829.1 - 7 6.3 13.7 4 7.1 3.1 3.3 2 1 1 3 3 3 0 A-kinase anchoring protein 95 (AKAP95) adh_short PF00106.20 CCC68830.1 - 2e-18 66.8 0.0 4.3e-18 65.7 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCC68830.1 - 2.7e-13 49.9 0.0 3.9e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CCC68830.1 - 0.0085 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Ribosomal_L17 PF01196.14 CCC68832.1 - 6.4e-28 97.1 0.8 1.9e-27 95.6 0.0 2.0 2 1 0 2 2 2 1 Ribosomal protein L17 Nop25 PF09805.4 CCC68832.1 - 6.4 6.8 9.6 0.42 10.6 2.8 1.8 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DSPc PF00782.15 CCC68833.1 - 1.1e-26 92.9 0.0 1.8e-21 76.1 0.0 3.6 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCC68833.1 - 1.6e-05 24.4 0.1 3.5e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase RE_SinI PF09570.5 CCC68833.1 - 0.024 13.6 0.0 0.059 12.3 0.0 1.6 1 0 0 1 1 1 0 SinI restriction endonuclease Peptidase_M1 PF01433.15 CCC68834.1 - 2.6e-06 26.7 3.6 0.23 10.4 0.1 3.6 3 1 1 4 4 4 3 Peptidase family M1 Mso1_Sec1_bdg PF14475.1 CCC68834.1 - 0.015 14.6 0.2 0.086 12.2 0.0 2.3 2 0 0 2 2 2 0 Sec1-binding region of Mso1 CBFD_NFYB_HMF PF00808.18 CCC68835.1 - 0.21 11.6 1.6 1.2 9.2 0.1 2.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Paf1 PF03985.8 CCC68836.1 - 5e-145 483.5 13.6 5.6e-145 483.4 9.4 1.0 1 0 0 1 1 1 1 Paf1 DUF2951 PF11166.3 CCC68836.1 - 9.1 6.2 11.2 0.088 12.6 0.9 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) RCC1_2 PF13540.1 CCC68837.1 - 1.1e-15 56.7 3.2 5.8e-05 22.5 0.0 5.3 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 CCC68837.1 - 4.3e-14 52.4 0.8 0.00036 20.6 0.4 5.5 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Peptidase_M20 PF01546.23 CCC68838.1 - 2.7e-24 85.7 0.0 4.2e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCC68838.1 - 1.9e-12 46.8 0.0 3.7e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain WD40 PF00400.27 CCC68838.1 - 1.6e-11 43.6 10.5 0.00053 19.7 0.1 6.1 5 1 0 5 5 5 4 WD domain, G-beta repeat Peptidase_M42 PF05343.9 CCC68838.1 - 0.063 12.0 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase MRP-L27 PF09809.4 CCC68839.1 - 3.9e-31 107.0 1.4 6.3e-31 106.3 1.0 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 SecY PF00344.15 CCC68840.1 - 2.3e-50 171.4 23.6 3.1e-50 171.0 16.4 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CCC68840.1 - 2.8e-07 29.9 0.3 2.8e-07 29.9 0.2 2.7 2 0 0 2 2 2 1 Plug domain of Sec61p A_deaminase PF00962.17 CCC68841.1 - 2.6e-18 66.0 0.0 5.9e-09 35.2 0.0 3.7 4 0 0 4 4 4 3 Adenosine/AMP deaminase Peptidase_M28 PF04389.12 CCC68842.1 - 2.5e-33 115.3 0.1 3.8e-33 114.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CCC68842.1 - 3.9e-08 32.9 0.0 8e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 CCC68842.1 - 0.0012 18.3 0.0 0.0018 17.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 CCC68842.1 - 0.0041 15.9 0.0 0.01 14.6 0.0 1.6 2 0 0 2 2 2 1 M42 glutamyl aminopeptidase Mem_trans PF03547.13 CCC68843.1 - 2.5e-63 213.6 16.8 4.3e-63 212.9 11.6 1.3 1 1 0 1 1 1 1 Membrane transport protein Cytokin_check_N PF10407.4 CCC68844.1 - 3.1e-29 100.4 1.6 1e-28 98.7 1.1 2.0 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus CAP PF00188.21 CCC68846.1 - 3.7e-20 72.6 5.5 7.4e-20 71.6 3.8 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TFIIA PF03153.8 CCC68846.1 - 8.6 6.1 14.0 13 5.5 9.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ras PF00071.17 CCC68847.1 - 4.1e-55 185.5 0.5 5e-55 185.2 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC68847.1 - 3.1e-22 79.3 0.2 5.9e-22 78.4 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC68847.1 - 8.5e-15 54.4 0.2 1.2e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCC68847.1 - 8.3e-08 31.6 0.1 1.2e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCC68847.1 - 2e-06 27.3 0.1 5.1e-06 26.0 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCC68847.1 - 2e-05 24.5 0.0 3.6e-05 23.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 CCC68847.1 - 0.0096 14.9 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Septin AAA_16 PF13191.1 CCC68847.1 - 0.01 15.8 0.8 0.064 13.2 0.5 2.1 1 1 1 2 2 2 0 AAA ATPase domain Polyoma_agno PF01736.11 CCC68847.1 - 0.072 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Polyomavirus agnoprotein DUF258 PF03193.11 CCC68847.1 - 0.1 11.7 0.3 0.29 10.3 0.1 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 Mitofilin PF09731.4 CCC68848.1 - 3.3e-88 296.8 25.1 2e-84 284.3 14.4 2.0 1 1 1 2 2 2 2 Mitochondrial inner membrane protein BAR PF03114.13 CCC68848.1 - 0.00045 19.8 3.0 0.00045 19.8 2.1 2.2 1 1 2 3 3 3 1 BAR domain IBR PF01485.16 CCC68849.1 - 2.9e-18 65.5 40.9 2.7e-10 39.9 2.8 3.9 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 CCC68849.1 - 8.7e-06 25.2 13.5 8.7e-06 25.2 9.4 5.0 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCC68849.1 - 3.3e-05 23.4 38.3 7.9e-05 22.2 6.2 4.6 4 1 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC68849.1 - 0.0052 16.7 12.1 0.0052 16.7 8.4 5.4 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) YL1 PF05764.8 CCC68849.1 - 2.6 7.6 4.4 4.3 6.8 3.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein DUF3808 PF10300.4 CCC68850.1 - 1.1e-169 564.9 2.9 1.4e-169 564.6 2.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_16 PF13432.1 CCC68850.1 - 0.049 14.3 2.0 0.45 11.2 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCC68850.1 - 0.078 12.9 0.4 1.5 8.8 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCC68850.1 - 0.081 12.8 0.4 20 5.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 CCC68850.1 - 0.36 11.3 8.8 2.1 8.9 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat EF-hand_4 PF12763.2 CCC68851.1 - 0.0013 18.3 0.7 0.0075 15.9 0.0 2.5 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF1932 PF09130.6 CCC68851.1 - 0.073 12.8 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1932) Vps51 PF08700.6 CCC68852.1 - 8.1e-12 44.8 1.2 1.9e-11 43.6 0.8 1.7 1 0 0 1 1 1 1 Vps51/Vps67 HBS1_N PF08938.5 CCC68852.1 - 0.025 14.6 0.3 0.025 14.6 0.2 2.6 2 1 1 3 3 3 0 HBS1 N-terminus Trypan_PARP PF05887.6 CCC68852.1 - 0.14 11.9 4.2 0.18 11.5 2.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Arrestin_C PF02752.17 CCC68853.1 - 4.4e-13 49.5 3.8 8.3e-13 48.6 0.0 3.0 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCC68853.1 - 1.4e-09 37.8 0.1 1.6e-05 24.7 0.1 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain NTR2 PF15458.1 CCC68854.1 - 1.8e-38 132.2 32.1 1.8e-38 132.2 22.3 1.3 2 0 0 2 2 2 1 Nineteen complex-related protein 2 Thioredoxin_5 PF13743.1 CCC68854.1 - 0.06 12.9 3.8 0.097 12.2 0.9 2.3 2 0 0 2 2 2 0 Thioredoxin SAPS PF04499.10 CCC68855.1 - 7.3e-164 545.8 7.6 7.3e-164 545.8 5.3 2.9 3 1 0 3 3 3 1 SIT4 phosphatase-associated protein ChAPs PF09295.5 CCC68856.1 - 1.1e-40 139.6 4.8 2.6e-31 108.7 0.8 2.2 2 0 0 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_11 PF13414.1 CCC68856.1 - 8.4e-07 28.5 0.1 3.1e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 CCC68856.1 - 7.8e-06 25.4 3.6 0.06 13.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCC68856.1 - 0.0037 17.1 0.4 0.23 11.4 0.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 CCC68856.1 - 0.0049 16.9 0.2 0.033 14.3 0.0 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCC68856.1 - 0.012 15.3 1.3 0.13 12.0 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCC68856.1 - 0.032 14.0 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat CytoC_RC PF02276.13 CCC68856.1 - 0.26 10.3 0.0 0.52 9.3 0.0 1.4 1 0 0 1 1 1 0 Photosynthetic reaction centre cytochrome C subunit GCS PF03074.11 CCC68857.1 - 1.8e-145 484.6 1.2 2.3e-145 484.3 0.8 1.1 1 0 0 1 1 1 1 Glutamate-cysteine ligase IF-2B PF01008.12 CCC68858.1 - 1.8e-77 260.0 0.0 2.2e-77 259.8 0.0 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 CCC68858.1 - 0.048 13.3 0.1 4.5 6.8 0.0 2.5 2 0 0 2 2 2 0 DeoR C terminal sensor domain Sin_N PF04801.8 CCC68859.1 - 5.2e-19 68.4 0.5 9e-19 67.6 0.4 1.3 1 1 0 1 1 1 1 Sin-like protein conserved region DEAD PF00270.24 CCC68860.1 - 2.4e-36 124.7 0.0 4.3e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 CCC68860.1 - 1.1e-17 63.3 0.0 2.6e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 CCC68860.1 - 1.4e-16 60.1 0.0 3.2e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC68860.1 - 0.00054 19.8 0.0 0.00054 19.8 0.0 3.0 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit zf-C2HC5 PF06221.8 CCC68861.1 - 5.1e-21 74.1 5.6 9e-21 73.3 3.8 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type zf-ribbon_3 PF13248.1 CCC68861.1 - 0.062 12.5 3.6 0.12 11.6 2.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain SET PF00856.23 CCC68862.1 - 6.5e-09 36.2 1.1 3.7e-08 33.8 0.0 2.7 3 0 0 3 3 3 1 SET domain PHD PF00628.24 CCC68862.1 - 2e-08 33.8 9.2 4.4e-08 32.7 6.4 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCC68862.1 - 0.016 14.4 4.2 0.032 13.5 2.9 1.4 1 0 0 1 1 1 0 PHD-finger UNC-50 PF05216.8 CCC68863.1 - 3.8e-91 304.4 19.6 4.5e-91 304.1 13.6 1.0 1 0 0 1 1 1 1 UNC-50 family PLDc PF00614.17 CCC68864.1 - 9.3e-18 63.4 4.1 8.2e-10 38.1 0.5 3.4 4 0 0 4 4 4 2 Phospholipase D Active site motif PLDc_2 PF13091.1 CCC68864.1 - 5.3e-12 45.5 0.2 2.4e-07 30.5 0.1 3.1 2 1 0 2 2 2 2 PLD-like domain PX PF00787.19 CCC68864.1 - 1.9e-05 24.4 5.0 0.0019 17.9 0.2 4.1 3 0 0 3 3 3 1 PX domain PH_2 PF08458.5 CCC68864.1 - 0.019 14.9 0.5 0.063 13.2 0.3 1.9 1 0 0 1 1 1 0 Plant pleckstrin homology-like region GATA PF00320.22 CCC68865.1 - 5.3e-14 51.2 3.0 9.3e-14 50.4 2.1 1.4 1 0 0 1 1 1 1 GATA zinc finger Auto_anti-p27 PF06677.7 CCC68865.1 - 0.024 14.3 0.1 0.046 13.4 0.1 1.4 1 0 0 1 1 1 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) eIF-5_eIF-2B PF01873.12 CCC68865.1 - 0.41 10.3 2.2 0.8 9.3 0.2 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Snf7 PF03357.16 CCC68866.1 - 2.9e-14 52.8 22.2 2.9e-14 52.8 15.4 1.3 1 1 0 1 1 1 1 Snf7 GrpE PF01025.14 CCC68866.1 - 0.26 10.8 12.6 0.014 14.9 4.9 1.6 2 0 0 2 2 2 0 GrpE SYCE1 PF15233.1 CCC68866.1 - 4.8 7.1 16.9 10 6.0 11.7 1.8 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 Cpn60_TCP1 PF00118.19 CCC68867.1 - 2.3e-146 488.2 4.7 2.6e-146 488.0 3.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Herpes_U59 PF04529.7 CCC68867.1 - 0.083 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus U59 protein WD40 PF00400.27 CCC68868.1 - 1.5e-34 116.6 11.4 4.6e-09 35.8 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 CCC68868.1 - 8e-05 22.2 1.1 0.0011 18.5 0.0 2.7 1 1 1 3 3 3 1 PQQ-like domain Nup160 PF11715.3 CCC68868.1 - 0.0004 18.6 5.6 0.0013 17.0 0.2 3.1 1 1 2 3 3 3 1 Nucleoporin Nup120/160 DUF3249 PF11615.3 CCC68868.1 - 0.092 12.4 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3249) DUF4614 PF15391.1 CCC68868.1 - 6.5 6.4 12.2 0.58 9.9 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4614) 5-FTHF_cyc-lig PF01812.15 CCC68869.1 - 3.3e-42 144.3 0.0 3.7e-42 144.1 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF2454 PF10521.4 CCC68869.1 - 0.064 12.2 0.3 0.15 11.0 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2454) FtsK_SpoIIIE_N PF12538.3 CCC68869.1 - 0.11 12.6 0.1 0.74 9.9 0.0 2.1 2 0 0 2 2 2 0 DNA transporter DASH_Spc34 PF08657.5 CCC68870.1 - 4.5e-63 213.3 7.2 5.1e-63 213.1 5.0 1.0 1 0 0 1 1 1 1 DASH complex subunit Spc34 Bacillus_HBL PF05791.6 CCC68870.1 - 0.001 18.5 6.5 0.0044 16.4 2.9 2.2 2 0 0 2 2 2 1 Bacillus haemolytic enterotoxin (HBL) DRIM PF07539.7 CCC68870.1 - 0.0054 16.1 0.9 0.012 15.0 0.1 1.9 2 0 0 2 2 2 1 Down-regulated in metastasis ATG16 PF08614.6 CCC68870.1 - 0.012 15.4 7.0 0.012 15.4 4.8 1.8 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DASH_Hsk3 PF08227.6 CCC68870.1 - 0.084 13.0 0.6 0.72 10.0 0.5 2.4 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like IncA PF04156.9 CCC68870.1 - 0.1 12.1 5.8 0.086 12.4 2.8 1.7 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 CCC68870.1 - 0.13 11.1 7.0 0.023 13.6 2.1 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 OmpH PF03938.9 CCC68870.1 - 0.45 10.4 4.2 0.81 9.6 2.9 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) TMF_DNA_bd PF12329.3 CCC68870.1 - 0.95 9.3 12.2 6.5 6.6 3.9 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 CCC68870.1 - 1.6 8.2 8.1 18 4.9 1.1 3.0 1 1 2 3 3 3 0 Septum formation initiator Occludin_ELL PF07303.8 CCC68870.1 - 1.8 9.3 8.0 0.22 12.2 1.9 2.1 2 0 0 2 2 2 0 Occludin homology domain Peptidase_M22 PF00814.20 CCC68871.1 - 4e-83 278.9 0.0 5e-83 278.6 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CmcH_NodU PF02543.10 CCC68871.1 - 0.01 15.0 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 0 Carbamoyltransferase F1F0-ATPsyn_F PF10791.4 CCC68872.1 - 6.7e-05 23.0 5.6 0.5 10.6 0.0 4.3 1 1 4 5 5 5 2 Mitochondrial F1-F0 ATP synthase subunit F of fungi NTF2 PF02136.15 CCC68872.1 - 0.0051 17.1 0.1 0.97 9.8 0.0 3.2 2 1 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain AA_permease PF00324.16 CCC68874.1 - 2.1e-143 478.1 39.7 2.4e-143 477.9 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC68874.1 - 1.2e-35 122.8 41.6 1.6e-35 122.5 28.8 1.1 1 0 0 1 1 1 1 Amino acid permease SUN PF03856.8 CCC68875.1 - 5.9e-104 346.7 15.6 9.4e-104 346.1 10.8 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF1869 PF08956.5 CCC68875.1 - 0.71 9.5 5.4 0.54 9.9 1.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1869) His_Phos_1 PF00300.17 CCC68876.1 - 1.3e-29 103.3 0.1 1.7e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 CCC68876.1 - 0.00014 21.3 0.0 0.00021 20.7 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Lectin_leg-like PF03388.8 CCC68877.1 - 9.1e-05 21.6 0.1 0.00044 19.4 0.0 1.9 2 0 0 2 2 2 1 Legume-like lectin family Lectin_legB PF00139.14 CCC68877.1 - 0.0042 16.4 0.8 0.019 14.3 0.6 1.8 1 1 0 1 1 1 1 Legume lectin domain MRAP PF15183.1 CCC68877.1 - 0.68 9.5 4.2 9.3 5.9 0.0 2.8 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family TrkH PF02386.11 CCC68880.1 - 3.5e-134 446.8 8.1 4.7e-132 439.8 1.4 2.1 2 0 0 2 2 2 2 Cation transport protein LSM PF01423.17 CCC68882.1 - 7e-14 51.1 0.1 1.2e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 LSM domain PUF PF00806.14 CCC68882.1 - 0.12 11.8 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Dimer_Tnp_hAT PF05699.9 CCC68883.1 - 7.6e-09 35.0 0.2 3.2e-08 33.0 0.1 2.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 CCC68883.1 - 0.0079 15.9 3.4 0.019 14.6 2.4 1.7 1 0 0 1 1 1 1 BED zinc finger zinc_ribbon_5 PF13719.1 CCC68883.1 - 0.018 14.5 0.3 0.041 13.4 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Terminase_GpA PF05876.7 CCC68883.1 - 0.022 13.1 0.1 0.032 12.5 0.1 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zinc_ribbon_4 PF13717.1 CCC68883.1 - 0.072 12.7 0.8 0.18 11.5 0.5 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DUF1687 PF07955.6 CCC68884.1 - 7.4e-30 103.6 0.1 8.6e-30 103.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1687) TPR_16 PF13432.1 CCC68885.1 - 7.5e-17 61.5 10.7 0.00019 22.0 0.0 5.9 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 CCC68885.1 - 7.5e-15 54.3 19.6 0.00036 20.1 0.1 6.9 6 1 0 7 7 6 4 TPR repeat TPR_19 PF14559.1 CCC68885.1 - 2.4e-13 50.2 11.2 3.9e-07 30.3 0.2 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCC68885.1 - 5.7e-13 48.6 17.1 0.00048 19.9 0.0 6.2 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 CCC68885.1 - 2.5e-12 45.6 20.7 0.027 14.3 0.1 10.3 11 0 0 11 11 11 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCC68885.1 - 3.9e-12 45.0 30.1 0.0037 16.9 0.1 8.8 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_1 PF00515.23 CCC68885.1 - 6.6e-12 44.5 19.8 0.0038 16.7 0.1 9.0 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCC68885.1 - 7.9e-10 38.1 11.8 0.048 13.8 0.0 6.2 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCC68885.1 - 1.3e-09 37.8 14.2 0.012 16.0 0.0 7.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCC68885.1 - 1.3e-08 34.7 1.6 0.055 14.1 0.0 6.8 6 2 2 8 8 7 1 Tetratricopeptide repeat Apc3 PF12895.2 CCC68885.1 - 3.8e-07 30.1 16.0 0.02 15.0 0.8 5.6 5 1 2 7 7 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CCC68885.1 - 0.00032 20.4 0.1 9 6.2 0.0 4.3 3 1 2 5 5 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCC68885.1 - 0.00055 19.0 0.5 1.9 7.4 0.0 3.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.1 CCC68885.1 - 0.0026 17.8 0.3 14 5.8 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 CCC68885.1 - 0.01 15.5 10.0 2.6 8.0 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat UFD1 PF03152.9 CCC68886.1 - 1.1e-73 246.1 0.0 1.4e-73 245.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 DUF2422 PF10337.4 CCC68887.1 - 3.3e-46 158.0 1.3 3.3e-46 158.0 0.9 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 CCC68887.1 - 3e-10 40.1 17.6 3e-10 40.1 12.2 3.2 3 1 0 3 3 3 1 Fusaric acid resistance protein-like ALMT PF11744.3 CCC68887.1 - 1e-06 27.6 11.9 2.6e-05 23.0 5.3 2.5 2 0 0 2 2 2 2 Aluminium activated malate transporter DUF2421 PF10334.4 CCC68887.1 - 8.2e-05 22.3 0.0 0.00019 21.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) NAP PF00956.13 CCC68888.1 - 9.9e-79 263.8 7.2 9.9e-79 263.8 5.0 2.1 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Ribosomal_L6 PF00347.18 CCC68888.1 - 0.032 14.7 0.0 0.078 13.4 0.0 1.6 1 0 0 1 1 1 0 Ribosomal protein L6 RLL PF10036.4 CCC68888.1 - 0.19 11.1 6.2 0.099 12.0 2.4 2.0 2 0 0 2 2 2 0 Putative carnitine deficiency-associated protein Nucleoplasmin PF03066.10 CCC68888.1 - 0.41 10.1 40.4 0.59 9.6 13.0 3.4 3 0 0 3 3 3 0 Nucleoplasmin CENP-B_dimeris PF09026.5 CCC68888.1 - 2.7 8.2 49.3 0.11 12.7 3.0 3.4 3 0 0 3 3 3 0 Centromere protein B dimerisation domain Solute_trans_a PF03619.11 CCC68889.1 - 2.7e-81 272.8 14.5 3.3e-81 272.6 10.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha FixP_N PF14715.1 CCC68889.1 - 0.21 11.0 5.4 0.93 8.9 1.9 2.9 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Mito_carr PF00153.22 CCC68890.1 - 6.8e-65 214.8 5.6 4.1e-22 77.7 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PAP2 PF01569.16 CCC68891.1 - 2.5e-12 46.5 2.0 3.4e-12 46.1 0.5 1.9 2 1 0 2 2 2 1 PAP2 superfamily DUF1772 PF08592.6 CCC68891.1 - 0.12 12.0 0.2 1.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DHC_N2 PF08393.8 CCC68892.1 - 5.5e-92 308.3 11.5 5.5e-92 308.3 7.9 5.6 7 0 0 7 7 6 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.7 CCC68892.1 - 7.3e-79 265.6 30.8 7.3e-79 265.6 21.3 4.8 5 0 0 5 5 5 1 Dynein heavy chain, N-terminal region 1 AAA_6 PF12774.2 CCC68892.1 - 2.4e-58 197.3 0.0 6.1e-58 196.0 0.0 1.7 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 Dynein_heavy PF03028.10 CCC68892.1 - 7.9e-39 133.2 0.0 7.9e-39 133.2 0.0 2.9 3 0 0 3 3 3 1 Dynein heavy chain and region D6 of dynein motor MT PF12777.2 CCC68892.1 - 1.8e-29 102.5 3.8 4e-29 101.4 2.6 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.2 CCC68892.1 - 3.7e-29 101.1 1.8 1.6e-28 99.1 1.2 2.1 1 0 0 1 1 1 1 ATP-binding dynein motor region D5 AAA_5 PF07728.9 CCC68892.1 - 5.2e-26 91.0 0.6 7.6e-10 38.6 0.0 5.9 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_8 PF12780.2 CCC68892.1 - 1.3e-23 83.3 0.1 3.9e-23 81.7 0.1 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.2 CCC68892.1 - 4.4e-17 62.0 0.1 8.5e-16 57.8 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA PF00004.24 CCC68892.1 - 2.1e-14 53.8 0.8 0.0018 18.5 0.0 6.7 7 0 0 7 7 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCC68892.1 - 2e-11 44.1 6.9 0.00012 22.1 0.0 6.8 7 0 0 7 7 5 2 AAA domain AAA_17 PF13207.1 CCC68892.1 - 1.8e-09 38.4 0.0 0.12 13.2 0.0 6.3 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 CCC68892.1 - 2.4e-09 37.2 0.0 0.0012 18.7 0.0 4.7 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 CCC68892.1 - 7.4e-09 35.8 0.0 0.38 10.7 0.0 4.7 4 0 0 4 4 4 3 AAA ATPase domain Zeta_toxin PF06414.7 CCC68892.1 - 9.9e-06 24.7 0.0 0.017 14.2 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin cobW PF02492.14 CCC68892.1 - 1.6e-05 24.4 0.5 0.01 15.2 0.0 3.1 3 0 0 3 3 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 CCC68892.1 - 3.5e-05 23.9 0.4 2.3 8.4 0.0 4.4 4 0 0 4 4 3 1 RNA helicase AAA_28 PF13521.1 CCC68892.1 - 4.8e-05 23.3 0.9 3.5 7.5 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 CCC68892.1 - 4.9e-05 23.6 9.2 3.1 8.1 0.0 7.0 6 0 0 6 6 5 2 AAA domain AAA_30 PF13604.1 CCC68892.1 - 0.0001 21.9 0.3 13 5.2 0.0 4.4 4 0 0 4 4 4 0 AAA domain NACHT PF05729.7 CCC68892.1 - 0.0002 21.0 0.2 0.9 9.1 0.0 3.7 3 0 0 3 3 3 2 NACHT domain Miro PF08477.8 CCC68892.1 - 0.00069 20.1 0.1 3.2 8.2 0.0 3.8 3 0 0 3 3 2 1 Miro-like protein IstB_IS21 PF01695.12 CCC68892.1 - 0.011 15.2 0.4 7.4 5.9 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 CCC68892.1 - 0.023 14.1 0.5 5.3 6.4 0.1 3.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Mg_chelatase PF01078.16 CCC68892.1 - 0.031 13.4 2.5 0.33 10.0 0.0 3.6 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 CCC68892.1 - 0.031 14.0 5.1 8.1 6.2 0.0 3.4 3 0 0 3 3 3 0 Part of AAA domain AAA_25 PF13481.1 CCC68892.1 - 0.19 11.1 0.3 51 3.1 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 CCC68892.1 - 0.26 10.8 2.6 4.8 6.7 0.1 3.7 4 0 0 4 4 4 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 CCC68892.1 - 0.3 10.5 0.1 27 4.1 0.0 3.0 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_10 PF12846.2 CCC68892.1 - 0.43 9.9 11.3 0.59 9.5 0.0 5.6 6 0 0 6 6 6 0 AAA-like domain Ras PF00071.17 CCC68893.1 - 5.1e-48 162.5 0.0 6.5e-48 162.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC68893.1 - 5.7e-15 55.8 0.0 1.4e-14 54.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCC68893.1 - 0.00014 21.1 0.0 0.00021 20.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.1 CCC68893.1 - 0.032 13.8 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CCC68893.1 - 0.094 11.8 0.0 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCC68893.1 - 0.11 12.6 0.1 0.45 10.6 0.0 2.1 2 1 0 2 2 2 0 AAA domain tRNA_U5-meth_tr PF05958.6 CCC68894.1 - 9.5e-23 80.4 0.1 3.4e-21 75.3 0.0 2.8 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase TRAM PF01938.15 CCC68894.1 - 6.4e-12 45.0 0.1 1.4e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 TRAM domain Methyltransf_31 PF13847.1 CCC68894.1 - 3.3e-11 43.0 0.2 1.3e-10 41.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.5 CCC68894.1 - 2.4e-06 27.2 0.1 0.00011 21.8 0.0 2.4 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 CCC68894.1 - 3.1e-06 27.7 0.0 1e-05 26.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCC68894.1 - 7.5e-06 25.4 0.0 1.9e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 CCC68894.1 - 1.1e-05 24.8 0.0 2.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.8 CCC68894.1 - 1.4e-05 24.4 0.0 2.9e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 CCC68894.1 - 0.00017 21.6 0.0 0.00034 20.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCC68894.1 - 0.00022 20.4 0.0 0.0046 16.0 0.0 2.4 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Met_10 PF02475.11 CCC68894.1 - 0.0013 18.3 0.1 0.025 14.1 0.0 2.5 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_25 PF13649.1 CCC68894.1 - 0.0014 18.9 0.0 0.0096 16.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 CCC68894.1 - 0.0059 15.6 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 CCC68894.1 - 0.0063 16.9 0.0 0.02 15.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_S21e PF01249.13 CCC68895.1 - 4.6e-39 132.2 0.0 5.1e-39 132.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Glyco_transf_8 PF01501.15 CCC68896.1 - 5.5e-28 97.9 0.2 1.6e-27 96.4 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 8 Retrotrans_gag PF03732.12 CCC68896.1 - 0.061 13.3 1.1 0.23 11.5 0.6 2.1 1 1 0 1 1 1 0 Retrotransposon gag protein DEAD PF00270.24 CCC68897.1 - 1.9e-42 144.6 1.7 3.8e-42 143.6 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC68897.1 - 7.3e-28 96.2 0.1 3.5e-27 94.0 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC68897.1 - 5.2e-05 23.1 0.0 0.00015 21.6 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 CCC68897.1 - 0.0032 17.2 0.1 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain DUF1253 PF06862.7 CCC68897.1 - 0.0036 15.7 0.2 0.63 8.3 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 CCC68897.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain AAA_30 PF13604.1 CCC68897.1 - 0.075 12.6 0.1 0.35 10.4 0.1 2.0 2 1 0 2 2 2 0 AAA domain Ribosomal_L1 PF00687.16 CCC68898.1 - 6.5e-45 153.1 2.0 7.8e-45 152.8 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Crust_neurohorm PF01147.12 CCC68898.1 - 0.057 12.7 0.7 0.2 10.9 0.5 1.9 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family Glyco_transf_15 PF01793.11 CCC68899.1 - 3.6e-128 427.1 13.9 4.2e-128 426.9 9.6 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase RNA_pol_Rpb4 PF03874.11 CCC68900.1 - 7.4e-36 122.7 12.0 2e-33 114.8 8.3 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb4 Daxx PF03344.10 CCC68900.1 - 0.0029 16.2 9.5 0.0037 15.8 6.6 1.2 1 0 0 1 1 1 1 Daxx Family IncFII_repA PF02387.10 CCC68900.1 - 0.26 10.3 8.9 0.46 9.5 6.2 1.4 1 0 0 1 1 1 0 IncFII RepA protein family BLVR PF06375.6 CCC68900.1 - 0.3 10.8 15.3 0.61 9.9 10.6 1.5 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Rtf2 PF04641.7 CCC68900.1 - 0.44 9.6 9.7 0.63 9.1 6.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger MRI PF15325.1 CCC68900.1 - 0.64 11.0 9.5 0.64 11.0 5.6 1.8 1 1 0 1 1 1 0 Modulator of retrovirus infection NOA36 PF06524.7 CCC68900.1 - 6.5 5.9 10.4 10 5.2 7.2 1.2 1 0 0 1 1 1 0 NOA36 protein TFIIE_beta PF02186.10 CCC68901.1 - 3.3e-20 71.8 0.9 7.8e-20 70.6 0.6 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain RNA_polI_A34 PF08208.6 CCC68902.1 - 2.1e-36 125.5 15.6 3.4e-36 124.7 10.8 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Peptidase_S49_N PF08496.5 CCC68902.1 - 3 7.6 12.7 16 5.2 6.9 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Las1 PF04031.8 CCC68903.1 - 4.7e-51 172.5 0.8 1.2e-50 171.1 0.6 1.7 1 0 0 1 1 1 1 Las1-like Zn_clus PF00172.13 CCC68904.1 - 3.1e-08 33.3 8.9 7e-08 32.2 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pam17 PF08566.5 CCC68905.1 - 3.2e-73 245.1 0.0 4e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 peroxidase PF00141.18 CCC68906.1 - 1.6e-40 139.0 0.0 2.7e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 Peroxidase Vps35 PF03635.12 CCC68907.1 - 3.8e-260 865.2 30.1 4.5e-260 865.0 20.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 PIR PF00399.14 CCC68908.1 - 4.6e-57 187.5 132.4 1.6e-07 30.4 3.9 10.4 5 4 5 10 10 10 9 Yeast PIR protein repeat HTH_37 PF13744.1 CCC68908.1 - 0.63 9.8 5.6 15 5.5 0.1 3.2 1 1 1 2 2 2 0 Helix-turn-helix domain GerPB PF10803.3 CCC68908.1 - 1.3 8.8 10.3 5.4 6.8 0.2 3.6 3 1 1 4 4 4 0 Spore germination GerPB PIR PF00399.14 CCC68909.1 - 1e-58 192.8 90.6 1e-08 34.2 1.7 7.8 7 0 0 7 7 7 7 Yeast PIR protein repeat HCV_NS5a_1a PF08300.8 CCC68909.1 - 0.017 15.0 2.3 23 4.9 0.1 3.6 1 1 4 5 5 5 0 Hepatitis C virus non-structural 5a zinc finger domain DUF2807 PF10988.3 CCC68909.1 - 0.13 11.7 16.7 0.28 10.7 7.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2807) Macoilin PF09726.4 CCC68909.1 - 3.3 5.8 8.5 4.1 5.5 5.9 1.0 1 0 0 1 1 1 0 Transmembrane protein PigN PF04987.9 CCC68910.1 - 1.6e-132 442.3 48.9 2.2e-132 441.8 33.9 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 CCC68910.1 - 4.4e-13 49.2 2.5 4.5e-10 39.4 0.2 2.1 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 CCC68910.1 - 2.7e-10 39.9 0.2 5.1e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 CCC68910.1 - 0.00028 20.3 0.1 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily MFS_1 PF07690.11 CCC68911.1 - 1.1e-21 77.0 8.1 3.8e-16 58.7 1.0 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2304 PF10066.4 CCC68911.1 - 6.1 6.7 10.8 0.16 11.8 2.2 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Pkinase PF00069.20 CCC68912.1 - 2.1e-68 230.2 0.0 3.6e-68 229.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68912.1 - 6.8e-37 126.9 0.0 9.4e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC68912.1 - 0.00019 20.4 0.0 0.0003 19.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCC68912.1 - 0.015 15.0 0.0 0.04 13.6 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family L51_S25_CI-B8 PF05047.11 CCC68913.1 - 1.6e-12 46.9 0.4 3.1e-12 46.0 0.1 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Arf PF00025.16 CCC68913.1 - 0.018 14.3 0.0 0.023 13.9 0.0 1.3 1 1 0 1 1 1 0 ADP-ribosylation factor family PMC2NT PF08066.7 CCC68913.1 - 0.028 14.7 0.2 0.043 14.1 0.1 1.3 1 0 0 1 1 1 0 PMC2NT (NUC016) domain Pkinase PF00069.20 CCC68914.1 - 7.1e-49 166.2 0.0 1.9e-48 164.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68914.1 - 1.1e-18 67.2 0.0 3.1e-18 65.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CCC68914.1 - 0.0033 17.0 4.3 0.015 14.8 0.1 2.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 CCC68914.1 - 0.0043 16.1 0.1 0.008 15.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCC68914.1 - 0.079 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CCC68914.1 - 0.14 11.8 0.1 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L14 PF00238.14 CCC68915.1 - 4.1e-42 142.7 1.2 4.6e-42 142.6 0.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Pkinase PF00069.20 CCC68916.1 - 3.5e-44 150.8 0.0 9.5e-29 100.3 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68916.1 - 1.8e-23 82.9 0.0 4.1e-18 65.3 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCC68916.1 - 0.0056 15.6 0.0 2 7.2 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 CCC68916.1 - 0.044 12.8 0.0 0.087 11.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family polyprenyl_synt PF00348.12 CCC68917.1 - 5.5e-85 284.3 0.1 6.5e-85 284.1 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase SdrG_C_C PF10425.4 CCC68917.1 - 0.0035 17.3 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 C-terminus of bacterial fibrinogen-binding adhesin GTP_EFTU PF00009.22 CCC68918.1 - 3e-38 131.1 0.0 4.8e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCC68918.1 - 1.8e-15 56.5 0.0 3.2e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 CCC68918.1 - 5.4e-15 55.0 0.0 1.7e-14 53.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCC68918.1 - 7.9e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 CCC68918.1 - 0.00015 21.5 0.0 0.00034 20.4 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 CCC68918.1 - 0.00068 20.1 0.1 0.0018 18.7 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCC68918.1 - 0.0015 18.4 0.2 0.0032 17.4 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 CCC68918.1 - 0.0024 17.2 0.2 0.012 15.0 0.2 2.1 1 1 0 1 1 1 1 Ras family AAA_16 PF13191.1 CCC68918.1 - 0.082 12.8 0.0 0.47 10.4 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AA_permease PF00324.16 CCC68919.1 - 4.5e-79 265.9 44.0 5.4e-79 265.7 30.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC68919.1 - 8.1e-39 133.3 50.5 1e-38 133.0 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease Zip PF02535.17 CCC68920.1 - 2.6e-24 85.8 14.3 4.3e-14 52.2 3.1 2.7 2 1 0 2 2 2 2 ZIP Zinc transporter Basic PF01586.11 CCC68920.1 - 0.11 13.2 2.7 0.53 11.0 0.5 2.7 2 0 0 2 2 2 0 Myogenic Basic domain DUF2401 PF10287.4 CCC68922.1 - 4.3e-93 311.1 3.5 6.5e-93 310.5 2.4 1.3 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 CCC68922.1 - 3.3e-26 91.2 0.3 1e-25 89.6 0.0 2.0 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) STE3 PF02076.10 CCC68923.1 - 2.1e-97 325.5 18.1 2.7e-97 325.2 12.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF2516 PF10724.4 CCC68923.1 - 0.12 12.3 0.2 0.12 12.3 0.1 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2516) CASP_C PF08172.7 CCC68924.1 - 6.9e-72 241.4 4.9 6.9e-72 241.4 3.4 5.1 2 1 2 4 4 4 1 CASP C terminal Lipoprotein_20 PF13942.1 CCC68924.1 - 0.0027 17.2 6.0 0.0027 17.2 4.1 5.8 4 2 2 6 6 6 1 YfhG lipoprotein Ribosomal_L22 PF00237.14 CCC68925.1 - 2e-33 114.4 0.1 2e-33 114.4 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e CRT10 PF08728.5 CCC68925.1 - 0.077 10.9 0.2 0.082 10.8 0.1 1.0 1 0 0 1 1 1 0 CRT10 Fis1_TPR_C PF14853.1 CCC68925.1 - 0.11 12.3 0.0 9.9 6.1 0.0 2.6 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MFS_1 PF07690.11 CCC68927.1 - 1.3e-26 93.1 17.3 1.3e-26 93.1 11.5 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily VIT1 PF01988.14 CCC68927.1 - 0.41 10.1 5.7 0.92 8.9 0.1 3.0 3 0 0 3 3 3 0 VIT family SSB PF00436.20 CCC68928.1 - 5.8e-18 64.6 0.1 6.9e-18 64.4 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family Mannosyl_trans3 PF11051.3 CCC68929.1 - 2e-85 286.4 0.0 2.9e-85 285.8 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 CCC68929.1 - 0.0018 17.6 0.3 0.0018 17.6 0.2 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 8 Ribosomal_L39 PF00832.15 CCC68930.1 - 1.5e-23 82.0 11.2 1.7e-23 81.7 7.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Gas_vesicle_C PF01304.12 CCC68930.1 - 0.067 12.8 1.4 0.099 12.2 1.0 1.2 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Ribosomal_S11 PF00411.14 CCC68931.1 - 2.4e-40 137.1 0.8 2.9e-40 136.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Beach PF02138.13 CCC68932.1 - 8.3e-111 369.7 0.2 2e-110 368.5 0.1 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 CCC68932.1 - 2.1e-12 46.8 0.0 9.3e-12 44.7 0.0 2.2 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 CCC68932.1 - 0.0079 16.4 0.4 0.017 15.3 0.0 1.7 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF1088 PF06469.6 CCC68932.1 - 0.025 13.9 0.1 0.063 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) Myb_DNA-binding PF00249.26 CCC68933.1 - 4.7e-16 58.5 0.0 1.5e-08 34.5 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCC68933.1 - 2.3e-06 27.6 0.3 0.027 14.5 0.1 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Neur_chan_memb PF02932.11 CCC68933.1 - 0.17 11.7 0.0 0.17 11.7 0.0 4.7 1 1 3 4 4 4 0 Neurotransmitter-gated ion-channel transmembrane region ELO PF01151.13 CCC68934.1 - 7.8e-62 208.8 22.4 9.5e-62 208.5 15.5 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Polysacc_synt_C PF14667.1 CCC68934.1 - 6.9 6.4 17.0 0.03 14.1 1.4 3.0 2 1 1 3 3 3 0 Polysaccharide biosynthesis C-terminal domain RNase_PH PF01138.16 CCC68935.1 - 1.8e-26 93.0 2.2 1e-25 90.5 0.5 2.6 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 PfkB PF00294.19 CCC68936.1 - 8.5e-45 153.1 0.3 4.6e-44 150.7 0.2 1.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF3369 PF11849.3 CCC68936.1 - 0.091 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3369) Phos_pyr_kin PF08543.7 CCC68936.1 - 0.12 11.5 0.7 2.3 7.3 0.1 2.7 2 1 0 2 2 2 0 Phosphomethylpyrimidine kinase NuA4 PF09340.5 CCC68936.1 - 0.13 11.8 0.4 0.27 10.9 0.3 1.4 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 DUF1205 PF06722.7 CCC68936.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1205) SPX PF03105.14 CCC68937.1 - 4.9e-42 144.6 19.1 4.9e-42 144.6 13.2 1.6 1 1 0 1 1 1 1 SPX domain CitMHS PF03600.11 CCC68937.1 - 3.7e-16 58.6 39.0 5.5e-14 51.5 14.1 2.1 1 1 1 2 2 2 2 Citrate transporter ATPase_gene1 PF09527.5 CCC68937.1 - 6.1 6.7 17.0 0.29 10.9 4.6 3.8 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) RasGEF PF00617.14 CCC68938.1 - 5.3e-46 156.7 1.8 5.3e-46 156.7 1.3 2.7 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CCC68938.1 - 3.6e-17 62.3 3.8 7.7e-16 58.0 0.4 3.6 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_1 PF00018.23 CCC68938.1 - 0.0018 17.6 0.1 0.004 16.5 0.1 1.6 1 0 0 1 1 1 1 SH3 domain RNase_H2_suC PF08615.6 CCC68939.1 - 2e-08 34.1 1.7 5e-08 32.8 1.2 1.6 1 1 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Lipoprotein_10 PF03202.8 CCC68939.1 - 0.02 14.8 2.6 0.027 14.4 1.8 1.1 1 0 0 1 1 1 0 Putative mycoplasma lipoprotein, C-terminal region DUF1366 PF07104.6 CCC68939.1 - 0.023 14.3 0.1 0.046 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) PG_binding_4 PF12229.3 CCC68939.1 - 0.07 13.3 0.3 0.07 13.3 0.2 1.8 2 0 0 2 2 2 0 Putative peptidoglycan binding domain His_kinase PF06580.8 CCC68939.1 - 0.1 12.5 0.2 0.15 12.0 0.2 1.3 1 0 0 1 1 1 0 Histidine kinase Homeobox PF00046.24 CCC68940.1 - 4.6e-12 45.3 1.4 7.4e-12 44.6 1.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCC68940.1 - 7.2e-05 22.4 0.3 0.0001 21.8 0.2 1.6 1 1 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 CCC68940.1 - 0.0064 15.5 0.0 0.0099 14.9 0.0 1.4 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez HTH_28 PF13518.1 CCC68940.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain AA_permease PF00324.16 CCC68942.1 - 4.4e-124 414.4 30.6 5e-124 414.2 21.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC68942.1 - 4.2e-31 107.9 30.5 5.3e-31 107.5 21.1 1.0 1 0 0 1 1 1 1 Amino acid permease Colicin_im PF03857.8 CCC68942.1 - 0.86 9.3 6.3 0.083 12.6 0.6 2.1 2 0 0 2 2 2 0 Colicin immunity protein DUF2416 PF10315.4 CCC68942.1 - 1.4 9.2 4.8 0.41 10.9 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2416) Rad60-SLD PF11976.3 CCC68943.1 - 2.7e-19 68.6 0.3 5.1e-19 67.7 0.1 1.5 1 1 1 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 CCC68943.1 - 1.4e-11 43.6 0.0 1.9e-11 43.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Pkinase PF00069.20 CCC68944.1 - 3.3e-73 246.0 0.0 1.1e-72 244.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC68944.1 - 3e-35 121.5 0.0 1.4e-34 119.3 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC68944.1 - 2.8e-06 26.5 0.6 2.9e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCC68944.1 - 0.19 11.4 0.1 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family PSP1 PF04468.7 CCC68945.1 - 4.2e-36 122.7 0.0 1.2e-35 121.3 0.0 1.9 1 0 0 1 1 1 1 PSP1 C-terminal conserved region PBP PF01161.15 CCC68946.1 - 1.3e-29 102.9 0.1 1.6e-29 102.6 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein E2R135 PF11570.3 CCC68946.1 - 0.036 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 PBP PF01161.15 CCC68947.1 - 2.9e-27 95.3 0.1 3.4e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF605 PF04652.11 CCC68948.1 - 3.3e-55 188.0 13.7 7.1e-55 186.9 9.5 1.5 1 1 0 1 1 1 1 Vta1 like PV-1 PF06637.6 CCC68948.1 - 0.18 10.3 10.2 0.31 9.5 7.1 1.3 1 0 0 1 1 1 0 PV-1 protein (PLVAP) S-AdoMet_synt_C PF02773.11 CCC68949.1 - 5.7e-75 249.6 0.2 9.8e-75 248.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 CCC68949.1 - 6.6e-47 158.3 0.0 1.4e-46 157.3 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 CCC68949.1 - 1.4e-44 150.4 0.1 3.1e-44 149.2 0.1 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain Ank_5 PF13857.1 CCC68950.1 - 8.3e-14 51.2 5.6 2.4e-07 30.7 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCC68950.1 - 4.6e-13 49.3 0.1 9.6e-06 25.8 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CCC68950.1 - 5.1e-13 47.8 2.0 1.6e-05 24.6 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 CCC68950.1 - 1.7e-12 46.4 0.9 9.3e-06 25.2 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 CCC68950.1 - 5.5e-11 42.6 2.7 2.5e-05 24.6 0.0 4.4 4 2 2 6 6 6 4 Ankyrin repeats (many copies) TEX13 PF15186.1 CCC68950.1 - 0.024 14.2 4.3 0.56 9.7 0.1 2.7 3 0 0 3 3 3 0 Testis-expressed sequence 13 protein family Atg14 PF10186.4 CCC68950.1 - 6.8 5.5 20.0 0.69 8.8 5.4 3.1 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 FHA PF00498.21 CCC68951.1 - 1.5e-08 34.6 0.0 4e-08 33.2 0.0 1.8 1 0 0 1 1 1 1 FHA domain TMPIT PF07851.8 CCC68951.1 - 0.96 8.4 4.0 1.7 7.6 2.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein RP-C_C PF11800.3 CCC68951.1 - 2.9 7.5 5.3 6.9 6.3 3.7 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region Ribosomal_L37e PF01907.14 CCC68952.1 - 6.8e-27 93.0 11.5 6.8e-27 93.0 7.9 1.6 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 CCC68952.1 - 0.00047 19.9 2.3 0.00068 19.4 1.6 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 CCC68952.1 - 0.0096 15.6 0.5 0.012 15.3 0.3 1.3 1 1 0 1 1 1 1 SelR domain C1_1 PF00130.17 CCC68952.1 - 0.04 13.6 2.3 0.066 12.9 1.6 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_5 PF14634.1 CCC68952.1 - 0.046 13.4 3.2 0.07 12.8 2.2 1.3 1 0 0 1 1 1 0 zinc-RING finger domain GATA PF00320.22 CCC68952.1 - 0.088 12.1 6.4 0.52 9.7 0.9 2.4 1 1 1 2 2 2 0 GATA zinc finger zinc_ribbon_6 PF14599.1 CCC68952.1 - 0.12 12.1 1.8 0.18 11.6 1.2 1.2 1 0 0 1 1 1 0 Zinc-ribbon C1_3 PF07649.7 CCC68952.1 - 0.22 11.5 1.5 3.1 7.9 0.1 2.2 2 0 0 2 2 2 0 C1-like domain zf-C3HC4_3 PF13920.1 CCC68952.1 - 0.22 11.1 2.6 0.31 10.7 1.8 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 CCC68952.1 - 0.35 10.1 5.0 0.75 9.0 0.6 2.1 1 1 2 3 3 3 0 zinc-ribbon domain GCC2_GCC3 PF07699.8 CCC68952.1 - 0.68 9.5 4.8 1.2 8.7 3.3 1.6 1 1 0 1 1 1 0 GCC2 and GCC3 zf-C3HC4_2 PF13923.1 CCC68952.1 - 0.91 9.6 4.8 1.4 8.9 3.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCC68952.1 - 1.2 8.8 4.9 1.9 8.2 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_2 PF13240.1 CCC68952.1 - 1.6 8.2 5.7 38 3.9 0.2 2.2 1 1 1 2 2 2 0 zinc-ribbon domain DUF2256 PF10013.4 CCC68952.1 - 5.8 6.7 8.9 3.3 7.5 1.6 2.6 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) PH PF00169.24 CCC68953.1 - 2.7e-07 30.7 0.2 5.5e-05 23.3 0.0 3.0 2 0 0 2 2 2 2 PH domain ABC_membrane PF00664.18 CCC68954.1 - 2e-58 197.9 7.2 2.6e-58 197.6 5.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CCC68954.1 - 2.1e-32 112.2 0.0 5.4e-32 110.9 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CCC68954.1 - 7e-08 31.9 0.6 6.8e-05 22.2 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCC68954.1 - 2.3e-06 27.7 0.1 5.4e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 CCC68954.1 - 7.2e-06 26.8 0.0 1.7e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.1 CCC68954.1 - 0.00023 21.2 0.2 0.11 12.4 0.1 2.4 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCC68954.1 - 0.0004 20.5 0.1 0.0031 17.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 CCC68954.1 - 0.00043 19.4 0.0 0.00083 18.5 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 CCC68954.1 - 0.00092 19.5 0.0 0.018 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 CCC68954.1 - 0.0011 18.1 0.1 0.0042 16.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 CCC68954.1 - 0.003 17.0 0.1 0.0082 15.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 CCC68954.1 - 0.0074 16.1 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCC68954.1 - 0.015 15.0 0.0 0.068 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 CCC68954.1 - 0.023 14.5 0.0 0.095 12.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_25 PF13481.1 CCC68954.1 - 0.029 13.7 0.0 0.16 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain 6PF2K PF01591.13 CCC68954.1 - 0.031 13.3 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase FtsK_SpoIIIE PF01580.13 CCC68954.1 - 0.033 13.6 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_10 PF12846.2 CCC68954.1 - 0.035 13.5 0.3 0.16 11.3 0.1 2.1 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 CCC68954.1 - 0.046 13.6 0.1 0.25 11.2 0.0 2.3 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.1 CCC68954.1 - 0.052 13.4 0.3 0.24 11.3 0.2 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Baculo_gp64 PF03273.8 CCC68954.1 - 0.052 11.7 0.1 0.074 11.2 0.1 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family AAA PF00004.24 CCC68954.1 - 0.058 13.5 0.2 2.7 8.2 0.0 3.4 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Glyco_transf_28 PF03033.15 CCC68955.1 - 2.2e-27 95.5 0.0 4.4e-27 94.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 CCC68955.1 - 9.3e-21 73.1 1.5 1.7e-13 49.8 0.1 3.5 3 0 0 3 3 3 2 GRAM domain UDPGT PF00201.13 CCC68955.1 - 1.7e-08 33.4 0.0 3.5e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH PF00169.24 CCC68955.1 - 1.9e-08 34.4 3.5 2.5e-07 30.8 0.3 3.7 3 0 0 3 3 3 1 PH domain Exo_endo_phos PF03372.18 CCC68956.1 - 4.5e-19 69.3 0.0 5.8e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family 2TM PF13239.1 CCC68956.1 - 0.14 12.2 1.3 0.32 11.1 0.9 1.5 1 0 0 1 1 1 0 2TM domain IncA PF04156.9 CCC68956.1 - 0.19 11.3 0.3 0.35 10.4 0.2 1.5 1 0 0 1 1 1 0 IncA protein PLDc_N PF13396.1 CCC68956.1 - 0.57 9.9 6.4 1.2 8.8 4.5 1.6 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal PepSY_TM_1 PF13172.1 CCC68956.1 - 8.6 6.2 13.7 8.7 6.2 0.0 3.4 3 0 0 3 3 3 0 PepSY-associated TM helix Spindle_Spc25 PF08234.7 CCC68957.1 - 8.8e-14 51.2 0.9 1.7e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 phiKZ_IP PF12699.2 CCC68957.1 - 0.0045 15.9 3.3 0.0057 15.6 2.3 1.2 1 0 0 1 1 1 1 phiKZ-like phage internal head proteins Seryl_tRNA_N PF02403.17 CCC68957.1 - 0.012 15.6 14.9 0.013 15.5 2.0 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain APG6 PF04111.7 CCC68957.1 - 0.012 14.7 20.0 0.015 14.3 13.2 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 CCC68957.1 - 0.02 14.6 17.8 0.37 10.6 2.2 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.6 CCC68957.1 - 0.021 14.6 5.4 0.021 14.6 3.7 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CCDC144C PF14915.1 CCC68957.1 - 0.033 13.1 18.6 0.11 11.3 12.0 1.9 1 1 1 2 2 2 0 CCDC144C protein coiled-coil region Exonuc_VII_L PF02601.10 CCC68957.1 - 0.047 12.8 8.8 0.052 12.7 6.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Circo_capsid PF02443.10 CCC68957.1 - 0.064 12.6 0.4 0.086 12.1 0.3 1.2 1 0 0 1 1 1 0 Circovirus capsid protein HR1 PF02185.11 CCC68957.1 - 0.094 12.4 12.9 1.6 8.5 2.9 3.2 2 1 0 2 2 2 0 Hr1 repeat Filament PF00038.16 CCC68957.1 - 0.12 11.8 19.2 0.58 9.5 13.2 1.9 1 1 0 1 1 1 0 Intermediate filament protein Myosin_tail_1 PF01576.14 CCC68957.1 - 0.12 10.0 18.1 0.17 9.5 12.5 1.2 1 0 0 1 1 1 0 Myosin tail DUF869 PF05911.6 CCC68957.1 - 0.23 9.6 14.5 0.29 9.3 10.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Laminin_II PF06009.7 CCC68957.1 - 0.26 11.0 8.2 0.049 13.3 1.8 2.1 1 1 1 2 2 2 0 Laminin Domain II Snapin_Pallidin PF14712.1 CCC68957.1 - 0.28 11.5 15.7 0.055 13.7 2.1 2.4 2 0 0 2 2 2 0 Snapin/Pallidin DUF1090 PF06476.7 CCC68957.1 - 0.45 10.1 8.8 0.82 9.3 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) CENP-F_leu_zip PF10473.4 CCC68957.1 - 0.55 10.0 20.7 0.26 11.1 7.5 2.2 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.3 CCC68957.1 - 0.72 9.6 16.1 0.27 10.9 8.5 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding GAS PF13851.1 CCC68957.1 - 1.6 7.8 22.3 0.44 9.7 9.3 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 CCC68957.1 - 2.4 7.7 22.2 5.9 6.4 12.6 2.0 1 1 1 2 2 2 0 IncA protein DUF4407 PF14362.1 CCC68957.1 - 3.4 6.5 6.2 4.5 6.1 4.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.7 CCC68957.1 - 3.7 7.3 17.9 4.5 7.0 3.4 2.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein Cep57_CLD_2 PF14197.1 CCC68957.1 - 3.7 7.5 12.4 3.7 7.5 0.9 2.8 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Atg14 PF10186.4 CCC68957.1 - 6.4 5.6 14.2 10 4.9 9.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin_2 PF01920.15 CCC68957.1 - 7.2 6.4 24.1 9.6 6.0 4.4 3.5 1 1 1 2 2 2 0 Prefoldin subunit DUF972 PF06156.8 CCC68957.1 - 7.8 6.8 19.0 8.7 6.7 6.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) AKNA PF12443.3 CCC68957.1 - 9.9 6.2 20.0 1.7 8.7 0.1 3.7 2 1 1 4 4 3 0 AT-hook-containing transcription factor Per1 PF04080.8 CCC68958.1 - 4.3e-94 314.8 20.6 4.3e-94 314.8 14.3 1.3 2 0 0 2 2 2 1 Per1-like DUF3753 PF12575.3 CCC68959.1 - 0.2 11.4 0.9 0.31 10.8 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) Nitroreductase PF00881.19 CCC68960.1 - 1.1e-06 28.5 0.0 1.9e-06 27.8 0.0 1.4 1 1 0 1 1 1 1 Nitroreductase family DUF512 PF04459.7 CCC68960.1 - 0.083 11.9 0.0 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF512) Nitroreductase PF00881.19 CCC68961.1 - 2.7e-05 24.0 0.1 4.2e-05 23.4 0.1 1.3 1 1 0 1 1 1 1 Nitroreductase family Nitroreductase PF00881.19 CCC68962.1 - 7.1e-10 38.9 0.0 9.1e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family SH3_9 PF14604.1 CCC68963.1 - 0.00012 21.5 0.0 0.00033 20.1 0.0 1.7 2 0 0 2 2 2 1 Variant SH3 domain SKG6 PF08693.5 CCC68963.1 - 0.0013 18.0 0.0 0.0024 17.1 0.0 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain SH3_1 PF00018.23 CCC68963.1 - 0.014 14.8 0.4 0.036 13.4 0.0 2.0 2 0 0 2 2 2 0 SH3 domain DUF4448 PF14610.1 CCC68963.1 - 0.049 13.1 0.6 0.25 10.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) SH3_2 PF07653.12 CCC68963.1 - 0.11 12.0 0.1 0.27 10.7 0.1 1.7 1 1 0 1 1 1 0 Variant SH3 domain MIP-T3 PF10243.4 CCC68964.1 - 5.6 5.3 92.4 10 4.4 64.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CAP_GLY PF01302.20 CCC68965.1 - 7.2e-18 64.0 0.4 2.2e-17 62.4 0.2 1.8 2 0 0 2 2 2 1 CAP-Gly domain Fez1 PF06818.10 CCC68965.1 - 0.066 13.2 29.2 0.51 10.3 5.5 2.4 1 1 1 2 2 2 0 Fez1 DUF948 PF06103.6 CCC68965.1 - 0.86 9.4 11.6 2.5 8.0 1.2 3.6 2 1 2 4 4 4 0 Bacterial protein of unknown function (DUF948) YlqD PF11068.3 CCC68965.1 - 0.99 9.4 29.0 0.52 10.3 4.0 2.8 2 1 1 3 3 3 0 YlqD protein Allexi_40kDa PF05549.6 CCC68965.1 - 1.2 8.4 23.1 0.16 11.2 2.8 2.7 1 1 1 3 3 3 0 Allexivirus 40kDa protein Pox_A_type_inc PF04508.7 CCC68965.1 - 1.4 8.8 15.6 2.1 8.3 1.5 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat CorA PF01544.13 CCC68965.1 - 3.5 6.5 16.5 5 6.0 3.9 2.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein DUF3584 PF12128.3 CCC68965.1 - 5.4 4.2 33.5 18 2.4 22.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Histidinol_dh PF00815.15 CCC68966.1 - 1.4e-184 613.4 2.0 2.4e-184 612.7 1.4 1.4 1 0 0 1 1 1 1 Histidinol dehydrogenase PRA-CH PF01502.13 CCC68966.1 - 4.2e-28 96.7 0.1 8.9e-28 95.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 CCC68966.1 - 9.2e-11 41.8 0.8 2.5e-10 40.4 0.5 1.8 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase RRP7 PF12923.2 CCC68967.1 - 9.3e-31 106.5 10.4 2e-30 105.4 7.2 1.6 1 0 0 1 1 1 1 Ribosomal RNA-processing protein 7 (RRP7) z-alpha PF02295.12 CCC68967.1 - 0.11 12.2 3.5 5 6.9 0.4 2.8 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain DUF45 PF01863.12 CCC68967.1 - 0.21 11.3 4.4 0.39 10.4 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF45 Ribosomal_L14e PF01929.12 CCC68967.1 - 0.83 10.0 10.9 0.16 12.3 1.8 3.0 2 1 1 3 3 3 0 Ribosomal protein L14 Ste50p-SAM PF09235.5 CCC68968.1 - 6e-28 96.6 3.5 1.7e-27 95.2 2.4 1.8 1 0 0 1 1 1 1 Ste50p, sterile alpha motif RA PF00788.18 CCC68968.1 - 8.5e-16 58.2 0.0 1.9e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SPX PF03105.14 CCC68968.1 - 0.06 13.1 8.2 0.16 11.7 5.7 1.7 1 1 0 1 1 1 0 SPX domain SelR PF01641.13 CCC68969.1 - 9.4e-50 167.4 0.5 1.1e-49 167.2 0.4 1.1 1 0 0 1 1 1 1 SelR domain GFA PF04828.9 CCC68969.1 - 0.0011 18.8 1.0 0.12 12.3 0.1 2.3 1 1 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme TF_Zn_Ribbon PF08271.7 CCC68969.1 - 0.013 14.7 0.8 0.39 10.0 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding HECT_2 PF09814.4 CCC68969.1 - 0.023 13.4 0.9 1.9 7.0 0.1 2.0 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF2296 PF10058.4 CCC68969.1 - 0.03 14.0 0.9 4.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) zf-ribbon_3 PF13248.1 CCC68969.1 - 0.035 13.3 5.3 0.77 9.0 1.0 2.6 2 1 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 CCC68969.1 - 0.046 13.5 3.1 0.28 11.0 2.2 2.0 1 1 1 2 2 2 0 Double zinc ribbon Ribosomal_L37e PF01907.14 CCC68969.1 - 0.057 13.2 5.0 0.092 12.5 0.4 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e zf-C4_Topoisom PF01396.14 CCC68969.1 - 0.064 12.7 1.3 7.1 6.2 0.1 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger NinF PF05810.7 CCC68969.1 - 0.067 13.0 0.2 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 NinF protein TFIIS_C PF01096.13 CCC68969.1 - 0.076 12.6 1.8 2.8 7.6 0.1 2.4 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) Zn_ribbon_recom PF13408.1 CCC68969.1 - 0.1 12.8 2.3 1.1 9.5 0.1 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DNA_RNApol_7kD PF03604.8 CCC68969.1 - 0.26 10.7 3.8 18 4.9 0.4 3.1 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zf-Mss51 PF13824.1 CCC68969.1 - 0.27 11.1 4.3 4.2 7.2 0.4 3.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 A2L_zn_ribbon PF08792.5 CCC68969.1 - 0.29 10.6 2.0 8.8 5.9 0.1 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain GCC2_GCC3 PF07699.8 CCC68969.1 - 0.56 9.8 3.8 2.7 7.6 1.2 2.3 2 0 0 2 2 2 0 GCC2 and GCC3 zinc_ribbon_2 PF13240.1 CCC68969.1 - 0.8 9.2 6.7 5.7 6.5 0.2 2.8 2 1 1 3 3 3 0 zinc-ribbon domain DUF1610 PF07754.6 CCC68969.1 - 6.1 7.0 6.4 8.2 6.6 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1610) GAT PF03127.9 CCC68970.1 - 0.00021 21.1 0.0 0.00055 19.8 0.0 1.7 1 0 0 1 1 1 1 GAT domain VHS PF00790.14 CCC68970.1 - 0.0034 17.0 0.6 0.0084 15.7 0.4 1.7 1 1 0 1 1 1 1 VHS domain Glutaredoxin PF00462.19 CCC68971.1 - 4.8e-15 55.2 0.0 7.4e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.1 CCC68971.1 - 7.5e-05 22.4 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 CCC68971.1 - 0.00036 20.1 0.0 0.0004 19.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin MafB19-deam PF14437.1 CCC68971.1 - 0.025 14.1 0.1 0.57 9.7 0.0 2.1 1 1 1 2 2 2 0 MafB19-like deaminase Thioredoxin_4 PF13462.1 CCC68971.1 - 0.03 14.3 1.1 0.22 11.5 0.0 1.9 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.1 CCC68971.1 - 0.032 14.4 0.2 0.043 14.0 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin-like domain S4 PF01479.20 CCC68971.1 - 0.088 12.2 0.6 3.3 7.2 0.0 2.7 2 1 1 3 3 3 0 S4 domain DSBA PF01323.15 CCC68971.1 - 0.14 11.7 0.1 0.69 9.4 0.1 1.9 1 1 0 1 1 1 0 DSBA-like thioredoxin domain NPR3 PF03666.8 CCC68972.1 - 0.00025 19.7 2.7 0.00025 19.7 1.9 2.3 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 DDHD PF02862.12 CCC68972.1 - 0.34 10.6 14.5 1.3 8.7 3.3 2.5 2 0 0 2 2 2 0 DDHD domain RP-C_C PF11800.3 CCC68972.1 - 0.42 10.2 8.0 0.2 11.3 0.3 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region Vfa1 PF08432.5 CCC68972.1 - 1.1 9.2 35.1 0.18 11.7 8.1 3.0 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 FAM60A PF15396.1 CCC68972.1 - 2.5 7.8 14.8 2.3 7.9 3.6 2.6 2 0 0 2 2 2 0 Protein Family FAM60A UPF0564 PF10595.4 CCC68972.1 - 3.9 6.2 30.8 0.072 11.9 4.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0564 Tom37_C PF11801.3 CCC68972.1 - 8.5 6.2 18.7 0.92 9.3 2.8 2.7 3 0 0 3 3 3 0 Tom37 C-terminal domain La PF05383.12 CCC68973.1 - 1.6e-17 63.0 0.1 4.2e-17 61.6 0.0 1.8 2 0 0 2 2 2 1 La domain Hid1 PF12722.2 CCC68973.1 - 0.35 8.5 29.7 0.03 12.0 17.0 1.7 1 1 1 2 2 2 0 High-temperature-induced dauer-formation protein ATG22 PF11700.3 CCC68974.1 - 5e-162 539.7 19.0 5.6e-162 539.5 13.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 CCC68974.1 - 2.4e-08 33.0 31.9 4.6e-08 32.1 11.0 3.0 2 2 1 3 3 3 3 Major Facilitator Superfamily WD40 PF00400.27 CCC68975.1 - 1.6e-22 78.5 3.8 0.00011 21.9 0.0 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat Hom_end PF05204.9 CCC68976.1 - 1.7e-14 53.7 0.0 2.2e-11 43.7 0.0 2.5 2 0 0 2 2 2 2 Homing endonuclease Hom_end_hint PF05203.11 CCC68976.1 - 5.4e-11 42.6 0.0 5.8e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Hom_end-associated Hint Hint_2 PF13403.1 CCC68976.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Hint domain Hexokinase_2 PF03727.11 CCC68977.1 - 3.5e-88 294.9 0.0 5e-88 294.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCC68977.1 - 9.4e-76 253.7 0.0 2.2e-75 252.4 0.0 1.6 2 0 0 2 2 2 1 Hexokinase Thioredoxin PF00085.15 CCC68978.1 - 1.7e-58 194.6 3.0 2.3e-30 104.3 0.1 3.5 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 CCC68978.1 - 1.9e-29 102.8 8.7 1.1e-22 80.7 0.3 4.5 3 1 2 5 5 5 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 CCC68978.1 - 1.7e-09 37.8 2.8 0.0022 18.1 0.3 4.1 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCC68978.1 - 3.2e-09 36.7 1.8 0.022 14.8 0.1 4.3 3 2 2 5 5 5 2 Thioredoxin-like Thioredoxin_7 PF13899.1 CCC68978.1 - 2.4e-08 33.8 0.1 0.00053 19.9 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like AhpC-TSA PF00578.16 CCC68978.1 - 4e-07 29.7 0.8 0.0048 16.5 0.0 3.5 3 1 1 4 4 4 2 AhpC/TSA family Redoxin PF08534.5 CCC68978.1 - 3.9e-05 23.2 2.4 0.047 13.2 0.0 3.0 4 0 0 4 4 4 2 Redoxin Thioredoxin_9 PF14595.1 CCC68978.1 - 0.0017 17.8 0.4 0.95 9.0 0.1 2.7 2 0 0 2 2 2 2 Thioredoxin Calsequestrin PF01216.12 CCC68978.1 - 0.002 16.9 0.0 0.0048 15.7 0.0 1.6 1 0 0 1 1 1 1 Calsequestrin Thioredoxin_4 PF13462.1 CCC68978.1 - 0.071 13.1 5.5 8.4 6.3 0.0 4.0 2 2 2 4 4 4 0 Thioredoxin DUF1539 PF07560.6 CCC68978.1 - 0.077 12.8 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) INTS5_N PF14837.1 CCC68978.1 - 0.13 11.6 0.8 0.45 9.9 0.1 2.0 2 0 0 2 2 2 0 Integrator complex subunit 5 N-terminus Mu-like_Com PF10122.4 CCC68978.1 - 0.29 10.2 0.6 10 5.2 0.0 2.5 2 0 0 2 2 2 0 Mu-like prophage protein Com Mgr1 PF08602.5 CCC68979.1 - 9.1e-133 442.7 0.3 1.1e-132 442.4 0.2 1.1 1 0 0 1 1 1 1 Mgr1-like, i-AAA protease complex subunit DUF1620 PF07774.8 CCC68980.1 - 2.7e-71 239.3 0.4 4.9e-71 238.4 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 CCC68980.1 - 0.01 15.2 0.2 0.042 13.3 0.1 2.1 2 1 1 3 3 3 0 PQQ-like domain DUF2645 PF10840.3 CCC68980.1 - 0.045 13.9 2.4 0.081 13.1 0.4 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2645) CTP_transf_2 PF01467.21 CCC68981.1 - 3.9e-06 26.9 0.0 8.1e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase QCR10 PF09796.4 CCC68983.1 - 0.036 13.7 3.6 0.036 13.7 2.5 2.1 2 1 1 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF3450 PF11932.3 CCC68983.1 - 0.14 11.4 0.7 0.16 11.2 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SSP160 PF06933.6 CCC68983.1 - 0.76 7.6 11.0 0.81 7.5 7.6 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 ATP_transf PF09830.4 CCC68984.1 - 5.6e-17 61.2 0.0 1e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 CCC68984.1 - 0.095 13.2 0.0 0.23 12.0 0.0 1.6 1 0 0 1 1 1 0 HIT domain PIG-X PF08320.7 CCC68986.1 - 6.9e-49 165.9 1.0 1.2e-48 165.1 0.7 1.4 1 0 0 1 1 1 1 PIG-X / PBN1 Spb1_C PF07780.7 CCC68987.1 - 4.4e-75 251.8 31.1 4.4e-75 251.8 21.6 3.9 2 1 2 4 4 4 1 Spb1 C-terminal domain DUF3381 PF11861.3 CCC68987.1 - 1.7e-53 180.3 22.0 1.7e-53 180.3 15.3 5.5 5 1 1 6 6 6 1 Domain of unknown function (DUF3381) FtsJ PF01728.14 CCC68987.1 - 3.3e-52 177.1 0.3 1.2e-51 175.3 0.1 2.1 2 0 0 2 2 2 1 FtsJ-like methyltransferase MT-A70 PF05063.9 CCC68988.1 - 2.1e-13 50.2 0.1 3.2e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 MT-A70 CHAP PF05257.11 CCC68989.1 - 0.043 13.4 0.0 0.081 12.5 0.0 1.4 1 0 0 1 1 1 0 CHAP domain Peptidase_M3 PF01432.15 CCC68991.1 - 8.6e-146 486.5 2.0 1.3e-145 485.9 1.4 1.3 1 0 0 1 1 1 1 Peptidase family M3 DUF543 PF04418.7 CCC68992.1 - 5.7e-30 103.0 0.0 6.2e-30 102.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Borrelia_orfA PF02414.10 CCC68993.1 - 0.021 13.9 19.3 0.025 13.7 13.4 1.2 1 0 0 1 1 1 0 Borrelia ORF-A Protamine_3 PF08188.6 CCC68993.1 - 0.39 10.7 13.3 0.2 11.6 5.5 2.6 2 1 0 2 2 2 0 Spermatozal protamine family DUF2361 PF10153.4 CCC68993.1 - 2.3 8.4 17.3 22 5.2 12.0 2.0 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) KH_1 PF00013.24 CCC68994.1 - 0.00037 20.0 0.0 0.00073 19.1 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CCC68994.1 - 0.04 13.5 0.0 0.081 12.6 0.0 1.5 1 0 0 1 1 1 0 KH domain ATP-synt_B PF00430.13 CCC68994.1 - 0.66 9.7 6.9 1.1 9.0 4.8 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) MRC1 PF09444.5 CCC68995.1 - 2e-47 161.1 13.3 2e-47 161.1 9.3 6.7 4 1 2 7 7 7 1 MRC1-like domain DGF-1_C PF11040.3 CCC68995.1 - 0.12 12.2 7.0 0.045 13.6 1.4 3.0 2 0 0 2 2 2 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus PALP PF00291.20 CCC68997.1 - 7.7e-64 215.8 0.0 8.8e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DAGK_cat PF00781.19 CCC68997.1 - 0.03 13.7 0.2 0.089 12.2 0.0 1.9 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain Peripla_BP_4 PF13407.1 CCC68997.1 - 0.032 13.5 0.1 0.08 12.2 0.0 1.6 2 0 0 2 2 2 0 Periplasmic binding protein domain Homeobox_KN PF05920.6 CCC68998.1 - 1.1e-07 31.4 0.1 2.9e-07 30.0 0.1 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CCC68998.1 - 4.4e-07 29.4 0.7 4.4e-07 29.4 0.5 2.1 2 1 0 2 2 2 1 Homeobox domain Homez PF11569.3 CCC68998.1 - 0.0024 16.8 0.8 0.005 15.8 0.5 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez DUF3573 PF12097.3 CCC68998.1 - 0.048 12.2 1.4 0.079 11.5 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ER PF01133.12 CCC68998.1 - 0.079 12.6 0.8 1.6 8.4 0.0 2.5 2 1 1 3 3 3 0 Enhancer of rudimentary MAT_Alpha1 PF04769.7 CCC68999.1 - 2e-08 33.8 0.4 2.6e-08 33.4 0.2 1.1 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 Sir1 PF11603.3 CCC69001.1 - 2.7e-05 24.2 0.0 5.2e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Regulatory protein Sir1 ALO PF04030.9 CCC69003.1 - 2.5e-93 312.4 2.1 3.4e-93 311.9 1.5 1.2 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 CCC69003.1 - 5.8e-28 97.1 0.1 8.4e-28 96.5 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 CCC69003.1 - 0.034 14.0 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 Berberine and berberine like Pyr_redox_3 PF13738.1 CCC69003.1 - 0.034 14.1 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SIS_2 PF13580.1 CCC69003.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 SIS domain F-box-like PF12937.2 CCC69004.1 - 3.6e-09 36.1 0.1 8.2e-09 35.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCC69004.1 - 1e-06 28.2 0.4 2.3e-06 27.0 0.3 1.7 1 0 0 1 1 1 1 F-box domain UIM PF02809.15 CCC69004.1 - 0.005 16.3 3.3 0.005 16.3 2.3 5.3 5 0 0 5 5 5 1 Ubiquitin interaction motif BEX PF04538.7 CCC69004.1 - 5.1 7.3 10.1 14 5.9 7.0 1.7 1 1 0 1 1 1 0 Brain expressed X-linked like family HMG_CoA_synt_C PF08540.5 CCC69005.1 - 1.7e-109 365.6 1.7 2.2e-109 365.3 1.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 CCC69005.1 - 1.6e-95 317.5 0.6 2.7e-95 316.8 0.4 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal RPM2 PF08579.6 CCC69006.1 - 4.7e-43 146.1 3.5 4.7e-43 146.1 2.4 4.1 5 0 0 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) PPR_2 PF13041.1 CCC69006.1 - 0.00015 21.6 0.7 2.3 8.2 0.1 4.5 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.15 CCC69006.1 - 0.017 15.0 0.1 10 6.3 0.0 4.1 3 0 0 3 3 3 0 PPR repeat Prefoldin PF02996.12 CCC69007.1 - 2.3e-25 88.5 2.3 2.9e-25 88.2 1.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit Peptidase_M13_N PF05649.8 CCC69007.1 - 0.038 13.0 4.1 0.047 12.7 2.8 1.2 1 0 0 1 1 1 0 Peptidase family M13 Omptin PF01278.15 CCC69007.1 - 0.055 12.5 0.1 0.072 12.1 0.1 1.1 1 0 0 1 1 1 0 Omptin family DUF3150 PF11348.3 CCC69007.1 - 0.061 12.4 4.2 1.6 7.8 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3150) NblA PF04485.7 CCC69007.1 - 4.1 7.3 10.1 2.3 8.1 0.8 3.4 3 0 0 3 3 3 0 Phycobilisome degradation protein nblA Rotamase_2 PF13145.1 CCC69007.1 - 7.6 7.1 9.1 0.97 10.0 2.5 2.0 2 1 0 2 2 2 0 PPIC-type PPIASE domain Rad10 PF03834.9 CCC69008.1 - 6.6e-27 92.9 1.8 1e-26 92.3 1.2 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Asn_synthase PF00733.16 CCC69009.1 - 1.1e-44 152.9 0.0 2e-44 152.0 0.0 1.5 1 1 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CCC69009.1 - 2.5e-14 53.0 0.0 2.8e-12 46.4 0.0 3.0 2 1 1 3 3 3 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CCC69009.1 - 7.2e-08 32.4 0.0 2.3e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CCC69009.1 - 0.027 13.6 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 Aluminium induced protein DUF3730 PF12530.3 CCC69009.1 - 0.033 14.0 0.0 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) VPS9 PF02204.13 CCC69010.1 - 9e-27 93.1 0.2 2.5e-26 91.6 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 CCC69010.1 - 8.4e-12 44.3 0.0 1.6e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 CUE domain ERO1 PF04137.10 CCC69011.1 - 2.4e-107 359.0 7.0 3.3e-107 358.5 4.9 1.2 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Fungal_trans_2 PF11951.3 CCC69012.1 - 6.1e-109 364.1 1.7 7.8e-109 363.7 1.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC69012.1 - 2.6e-11 43.2 6.1 2.6e-11 43.2 4.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2363 PF10155.4 CCC69012.1 - 0.00055 19.8 0.6 0.2 11.6 0.0 3.0 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2363) Ribonuclease_3 PF00636.21 CCC69013.1 - 2e-21 76.5 1.2 9.7e-21 74.3 0.0 2.7 3 0 0 3 3 3 1 Ribonuclease III domain dsrm PF00035.20 CCC69013.1 - 1.4e-15 57.6 0.0 1.2e-07 32.1 0.0 2.6 2 0 0 2 2 2 2 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 CCC69013.1 - 1.1e-14 54.4 0.1 2.3e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like SRP1_TIP1 PF00660.12 CCC69014.1 - 1.1e-06 28.4 10.6 0.0005 19.8 0.2 4.1 3 2 0 3 3 3 2 Seripauperin and TIP1 family zf-CCHC PF00098.18 CCC69015.1 - 0.00015 21.5 3.1 0.00024 20.8 2.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 CCC69015.1 - 0.023 14.3 1.2 0.045 13.4 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle AbiH PF14253.1 CCC69015.1 - 0.029 13.9 3.9 0.015 14.9 0.8 1.8 2 0 0 2 2 2 0 Bacteriophage abortive infection AbiH Tubulin PF00091.20 CCC69016.1 - 3.2e-70 236.2 0.0 4.3e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCC69016.1 - 1.4e-49 167.3 0.1 2.2e-49 166.7 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Sugar_tr PF00083.19 CCC69017.1 - 1.3e-42 145.9 19.2 2e-42 145.3 13.3 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC69017.1 - 2.9e-19 68.9 14.5 1.7e-11 43.4 7.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BRI3BP PF14965.1 CCC69017.1 - 0.027 13.8 0.4 0.11 11.8 0.3 2.1 1 0 0 1 1 1 0 Negative regulator of p53/TP53 SQS_PSY PF00494.14 CCC69018.1 - 1.1e-41 142.9 0.0 1.3e-41 142.6 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Pept_tRNA_hydro PF01195.14 CCC69019.1 - 1.5e-40 138.6 0.0 1.8e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase RNB PF00773.14 CCC69020.1 - 4.2e-67 226.7 0.1 4.2e-67 226.7 0.1 1.7 2 0 0 2 2 2 1 RNB domain Exo_endo_phos PF03372.18 CCC69021.1 - 5.6e-25 88.7 0.1 7.1e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ku PF02735.11 CCC69022.1 - 2.9e-34 118.2 0.4 8.5e-34 116.7 0.3 1.7 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CCC69022.1 - 1.1e-31 109.9 0.9 2.7e-31 108.7 0.6 1.7 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 CCC69022.1 - 1.8e-09 38.0 0.2 6.9e-09 36.1 0.2 2.1 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm DUF1767 PF08585.7 CCC69023.1 - 0.092 13.0 0.1 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1767) DUF1767 PF08585.7 CCC69024.1 - 0.092 13.0 0.1 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1767) Init_tRNA_PT PF04179.7 CCC69025.1 - 2.7e-149 497.8 0.0 3.1e-149 497.7 0.0 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase PRP38 PF03371.10 CCC69026.1 - 1.2e-47 161.7 3.8 1.5e-47 161.4 2.7 1.0 1 0 0 1 1 1 1 PRP38 family ATP13 PF12921.2 CCC69027.1 - 1.6e-19 69.5 1.2 1.5e-18 66.3 0.1 2.7 2 0 0 2 2 2 1 Mitochondrial ATPase expression PIG-L PF02585.12 CCC69028.1 - 5.6e-17 62.4 0.1 9.1e-17 61.7 0.1 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Fungal_trans PF04082.13 CCC69029.1 - 4.8e-34 117.4 6.0 1.2e-33 116.1 4.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC69029.1 - 2.3e-10 40.2 13.3 2.3e-10 40.2 9.2 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 CCC69030.1 - 1.8e-33 115.7 56.2 3e-33 114.9 36.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCC69030.1 - 4.9e-05 22.0 41.6 0.0028 16.2 10.1 3.3 1 1 3 4 4 4 2 Sugar (and other) transporter MFS_2 PF13347.1 CCC69030.1 - 0.0048 15.3 5.6 0.0048 15.3 3.9 3.5 1 1 2 3 3 3 1 MFS/sugar transport protein DUF998 PF06197.8 CCC69030.1 - 0.87 8.8 35.6 0.043 13.1 5.5 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF998) PGM_PMM_I PF02878.11 CCC69031.1 - 1.2e-37 128.4 0.0 2.1e-37 127.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 CCC69031.1 - 2.9e-20 72.5 0.0 7.6e-20 71.1 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 CCC69031.1 - 7.1e-14 51.8 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 CCC69031.1 - 3e-07 30.3 0.0 7e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain NIF PF03031.13 CCC69032.1 - 8.2e-26 90.5 1.2 8.5e-25 87.2 0.0 2.7 1 1 1 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 CCC69032.1 - 4.8e-13 49.0 0.1 1.4e-12 47.5 0.1 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCC69032.1 - 5.1e-06 26.2 0.0 9.7e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain ATP-synt_J PF04911.7 CCC69032.1 - 0.026 13.9 0.1 0.051 13.0 0.1 1.4 1 0 0 1 1 1 0 ATP synthase j chain ubiquitin PF00240.18 CCC69033.1 - 3e-18 64.9 0.1 4.8e-18 64.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCC69033.1 - 8.9e-10 38.1 0.1 1.4e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 CCC69033.1 - 9e-09 34.9 0.0 2.1e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Ubiquitin_2 PF14560.1 CCC69033.1 - 0.0016 18.6 0.1 0.0038 17.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-like domain CUE PF02845.11 CCC69033.1 - 0.022 14.2 0.1 0.044 13.2 0.1 1.5 1 0 0 1 1 1 0 CUE domain Rad60-SLD_2 PF13881.1 CCC69033.1 - 0.022 14.6 0.0 0.05 13.4 0.0 1.6 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCC69033.1 - 0.036 14.2 0.0 0.071 13.3 0.0 1.5 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Auxin_repressed PF05564.7 CCC69033.1 - 2 9.0 11.4 1.2 9.6 2.7 2.7 2 2 0 2 2 2 0 Dormancy/auxin associated protein Bul1_N PF04425.7 CCC69034.1 - 8.7e-152 505.6 0.1 8.7e-152 505.6 0.0 3.0 3 0 0 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 CCC69034.1 - 9.3e-105 349.6 18.0 9.3e-105 349.6 12.5 2.4 2 0 0 2 2 2 1 Bul1 C terminus Bul1_N PF04425.7 CCC69035.1 - 4.4e-165 549.5 0.1 4.4e-165 549.5 0.0 2.4 2 1 1 3 3 3 1 Bul1 N terminus Bul1_C PF04426.7 CCC69035.1 - 1.1e-118 395.3 11.8 1.1e-118 395.3 8.2 2.2 2 0 0 2 2 2 1 Bul1 C terminus Abi PF02517.11 CCC69036.1 - 6.4e-12 45.4 4.4 6.4e-12 45.4 3.1 2.1 3 0 0 3 3 3 1 CAAX protease self-immunity DUF543 PF04418.7 CCC69036.1 - 0.075 13.0 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF543) DUF3799 PF12684.2 CCC69036.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 PDDEXK-like domain of unknown function (DUF3799) Cyt-b5 PF00173.23 CCC69037.1 - 2.8e-20 71.8 0.3 7.7e-20 70.4 0.2 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 CCC69037.1 - 1.4e-11 44.8 18.7 1.4e-11 44.8 12.9 2.3 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 CCC69037.1 - 0.078 12.9 0.2 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Pribosyltran PF00156.22 CCC69038.1 - 5.5e-17 61.6 0.5 1e-16 60.7 0.4 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain RRN9 PF10680.4 CCC69039.1 - 2.5e-15 55.9 0.2 5.5e-15 54.8 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase I specific transcription initiation factor Cupredoxin_1 PF13473.1 CCC69039.1 - 0.044 13.6 1.3 1.3 8.9 0.9 2.6 1 1 0 1 1 1 0 Cupredoxin-like domain DUF4325 PF14213.1 CCC69039.1 - 0.4 10.3 6.3 2.1 8.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4325) DUF1043 PF06295.7 CCC69039.1 - 4.5 6.9 8.3 14 5.3 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) G-patch PF01585.18 CCC69040.1 - 0.0016 18.2 0.4 0.0062 16.2 0.3 2.1 1 0 0 1 1 1 1 G-patch domain DDHD PF02862.12 CCC69040.1 - 0.0065 16.2 8.7 0.0074 16.1 6.0 1.3 1 0 0 1 1 1 1 DDHD domain Zip PF02535.17 CCC69040.1 - 0.84 8.5 9.7 0.96 8.3 6.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter U79_P34 PF03064.11 CCC69040.1 - 1.4 8.3 25.1 2 7.8 17.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 GAGA_bind PF06217.7 CCC69040.1 - 1.6 8.6 17.8 2.4 8.0 12.4 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4604 PF15377.1 CCC69040.1 - 2.1 8.5 35.7 3.8 7.6 24.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) RR_TM4-6 PF06459.7 CCC69040.1 - 2.2 8.0 16.0 2.8 7.7 11.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hid1 PF12722.2 CCC69040.1 - 4 4.9 12.6 4.4 4.8 8.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2201_N PF13203.1 CCC69040.1 - 5.8 5.9 14.3 7.6 5.6 9.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain RP-C_C PF11800.3 CCC69040.1 - 8.8 5.9 9.5 13 5.4 6.6 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region RRM_1 PF00076.17 CCC69041.1 - 3e-39 132.5 1.9 1.1e-14 53.7 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC69041.1 - 1.4e-33 114.7 0.9 1.6e-09 37.5 0.0 4.4 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC69041.1 - 1.5e-10 40.7 4.4 9.1e-05 22.2 0.0 4.0 5 0 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.6 CCC69041.1 - 8.1e-07 28.1 3.8 2.6e-06 26.5 2.7 2.0 1 0 0 1 1 1 1 Lsm interaction motif Nup35_RRM_2 PF14605.1 CCC69041.1 - 0.012 15.3 0.0 2.8 7.8 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 CCC69041.1 - 0.02 14.6 0.1 2.7 7.7 0.0 2.7 2 0 0 2 2 2 0 Limkain b1 Pyrophosphatase PF00719.14 CCC69042.1 - 6.1e-49 165.4 0.0 8.2e-49 165.0 0.0 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase SNAP PF14938.1 CCC69043.1 - 5.2e-106 353.9 8.1 5.8e-106 353.7 5.6 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 CCC69043.1 - 7.8e-07 28.9 6.6 0.0032 17.3 0.7 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 CCC69043.1 - 3.3e-05 24.0 3.1 10 6.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 CCC69043.1 - 0.00041 19.9 0.8 0.11 12.3 0.1 4.1 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCC69043.1 - 0.00049 19.8 1.1 3 7.9 0.1 4.7 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCC69043.1 - 0.00058 19.3 2.7 0.94 9.2 0.1 5.0 4 2 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCC69043.1 - 0.0051 16.4 9.8 0.03 13.9 0.1 3.6 1 1 3 4 4 4 2 TPR repeat TPR_19 PF14559.1 CCC69043.1 - 0.0054 17.0 5.4 0.23 11.8 0.3 4.0 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCC69043.1 - 0.0066 17.0 0.9 0.48 11.1 0.0 3.0 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCC69043.1 - 0.012 15.2 3.9 0.52 10.2 0.1 4.0 2 2 1 4 4 4 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 CCC69043.1 - 0.016 14.6 0.2 0.051 13.0 0.1 1.6 1 1 0 1 1 1 0 Foie gras liver health family 1 Spatacsin_C PF14649.1 CCC69043.1 - 0.052 12.4 0.6 0.33 9.8 0.1 2.1 1 1 0 2 2 2 0 Spatacsin C-terminus DUF2225 PF09986.4 CCC69043.1 - 0.2 11.0 4.8 1.3 8.4 0.8 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) DUF221 PF02714.10 CCC69044.1 - 9.2e-113 376.3 26.1 9.2e-113 376.3 18.1 1.8 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCC69044.1 - 3.3e-41 140.4 1.6 3.3e-41 140.4 1.1 2.8 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 CCC69044.1 - 4.2e-27 93.8 0.0 1.1e-26 92.5 0.0 1.7 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 CCC69044.1 - 2.3e-09 37.6 0.2 4.1e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF2410 PF10307.4 CCC69045.1 - 1.7e-47 161.4 0.8 2.5e-47 160.8 0.6 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) CUE PF02845.11 CCC69046.1 - 7.5e-11 41.3 0.1 1.2e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 CUE domain SAP30_Sin3_bdg PF13867.1 CCC69047.1 - 4.5e-12 45.6 0.2 7.8e-10 38.4 0.1 2.5 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 HTH_19 PF12844.2 CCC69047.1 - 0.12 12.4 0.1 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain KMP11 PF03037.11 CCC69047.1 - 0.87 10.2 5.3 0.41 11.2 1.9 1.8 2 0 0 2 2 2 0 Kinetoplastid membrane protein 11 TatD_DNase PF01026.16 CCC69048.1 - 1.2e-34 119.6 0.0 1.5e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase eIF-1a PF01176.14 CCC69049.1 - 1.6e-26 91.4 0.2 2.2e-26 91.0 0.2 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 CCC69049.1 - 0.027 14.5 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain DUF1018 PF06252.7 CCC69052.1 - 1.8 9.0 7.5 4.3 7.8 5.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) EamA PF00892.15 CCC69053.1 - 2.6e-29 101.8 26.0 1.3e-16 60.7 3.3 2.4 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 CCC69053.1 - 2e-07 31.2 8.9 2e-07 31.2 6.2 3.5 3 1 0 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 CCC69053.1 - 8.7e-07 28.0 15.2 2.4e-05 23.3 10.5 2.0 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 CCC69053.1 - 0.00092 18.2 14.3 0.0022 16.9 0.1 2.6 2 1 1 3 3 3 1 UAA transporter family TPT PF03151.11 CCC69053.1 - 0.0021 17.6 5.5 0.0021 17.6 3.8 2.5 2 0 0 2 2 2 1 Triose-phosphate Transporter family Frag1 PF10277.4 CCC69053.1 - 0.013 15.0 7.5 0.044 13.2 5.2 2.0 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family RseC_MucC PF04246.7 CCC69053.1 - 0.41 10.2 9.1 1.2 8.6 1.0 3.5 2 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC UPF0060 PF02694.10 CCC69053.1 - 5.1 7.1 13.2 7.6 6.6 0.6 2.8 2 1 0 2 2 2 0 Uncharacterised BCR, YnfA/UPF0060 family Regulator_TrmB PF11495.3 CCC69054.1 - 0.1 11.5 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB HMG_box PF00505.14 CCC69054.1 - 0.7 10.1 4.6 0.36 11.1 1.0 2.1 2 1 0 2 2 2 0 HMG (high mobility group) box Pyridoxal_deC PF00282.14 CCC69056.1 - 2.9e-55 187.2 0.0 4.5e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Homeobox_KN PF05920.6 CCC69056.1 - 0.094 12.4 0.2 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 Homeobox KN domain SAM_decarbox PF01536.11 CCC69057.1 - 1.7e-114 381.9 8.1 1.9e-114 381.7 5.6 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase CBM-like PF14683.1 CCC69057.1 - 0.02 14.5 0.6 0.047 13.3 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain III zf-RING_2 PF13639.1 CCC69058.1 - 1e-08 34.8 6.8 2.6e-08 33.5 4.7 1.8 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCC69058.1 - 3.8e-07 30.1 3.3 9.7e-07 28.8 2.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 CCC69058.1 - 1.8e-05 24.5 5.2 7.1e-05 22.6 3.6 2.0 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 CCC69058.1 - 0.00061 19.5 1.8 0.0014 18.4 1.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CCC69058.1 - 0.011 15.3 7.9 0.032 13.8 5.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 CCC69058.1 - 0.021 14.8 6.3 0.067 13.2 4.4 2.0 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 CCC69058.1 - 0.043 13.8 8.1 0.16 12.0 5.6 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 CCC69058.1 - 0.092 12.3 5.7 0.53 9.9 0.7 2.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CCC69058.1 - 0.11 12.2 6.3 2.4 7.8 4.3 2.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 CCC69058.1 - 0.2 11.4 2.4 7.1 6.4 0.5 2.5 1 1 1 2 2 2 0 Zinc-binding RING-finger zf-RING-like PF08746.6 CCC69058.1 - 0.25 11.3 6.4 0.58 10.2 4.5 1.7 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 CCC69058.1 - 4.1 7.1 6.0 8.3 6.1 4.1 1.6 1 0 0 1 1 1 0 PHD-finger Glyco_transf_8 PF01501.15 CCC69059.1 - 5.8e-07 29.0 12.2 1.4e-06 27.8 6.4 2.9 2 1 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 CCC69059.1 - 0.0026 17.1 0.3 0.0053 16.1 0.2 1.5 1 0 0 1 1 1 1 Mannosyltransferase putative AMP-binding PF00501.23 CCC69060.1 - 5.4e-75 252.3 0.0 7.5e-75 251.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCC69060.1 - 0.072 14.0 0.0 0.19 12.7 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain COX6B PF02297.12 CCC69061.1 - 5.3e-22 77.6 2.9 7.3e-22 77.1 2.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Bac_rhodopsin PF01036.13 CCC69062.1 - 1.2e-56 191.5 17.9 1.4e-56 191.3 12.4 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein DUF4131 PF13567.1 CCC69062.1 - 0.079 12.3 10.8 0.28 10.5 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Cation_efflux PF01545.16 CCC69064.1 - 1.1e-80 270.8 3.6 1.3e-80 270.4 2.5 1.0 1 0 0 1 1 1 1 Cation efflux family TcpE PF12648.2 CCC69064.1 - 3.1 7.9 5.7 14 5.9 0.3 2.6 2 1 1 3 3 3 0 TcpE family Ribosomal_L18ae PF01775.12 CCC69065.1 - 3.4e-45 152.9 4.0 3.4e-45 152.9 2.7 1.4 2 0 0 2 2 2 1 Ribosomal L18ae/LX protein domain DUF1057 PF06342.7 CCC69065.1 - 0.055 12.2 0.4 0.11 11.2 0.1 1.5 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Mito_carr PF00153.22 CCC69066.1 - 2.5e-32 110.4 5.7 1.4e-12 47.0 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein UPF0444 PF15475.1 CCC69066.1 - 2.8 8.0 6.7 36 4.4 2.1 3.4 3 1 0 3 3 3 0 Transmembrane protein C12orf23, UPF0444 UBACT PF02134.16 CCC69067.1 - 0.12 11.9 0.2 0.3 10.7 0.0 1.7 2 0 0 2 2 2 0 Repeat in ubiquitin-activating (UBA) protein DUF382 PF04037.8 CCC69068.1 - 2e-49 166.6 0.1 2e-49 166.6 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF382) PSP PF04046.11 CCC69068.1 - 1.4e-19 69.2 1.3 2.4e-19 68.4 0.9 1.4 1 0 0 1 1 1 1 PSP Ribonuclease_3 PF00636.21 CCC69069.1 - 4.2e-15 56.1 0.0 4.2e-15 56.1 0.0 4.2 3 1 0 3 3 3 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 CCC69069.1 - 2.7e-12 46.7 0.5 1e-11 44.9 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease-III-like dsrm PF00035.20 CCC69069.1 - 0.00013 22.4 0.0 0.00013 22.4 0.0 3.5 3 0 0 3 3 3 1 Double-stranded RNA binding motif RCC1 PF00415.13 CCC69070.1 - 1.9e-17 63.1 0.6 1.8e-06 28.0 0.0 5.0 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 CCC69070.1 - 3.4e-12 46.3 14.6 7.6e-09 35.5 0.1 4.7 3 2 1 4 4 4 3 BTB/POZ domain RCC1_2 PF13540.1 CCC69070.1 - 2.2e-09 36.6 9.1 0.015 14.9 0.0 3.6 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat NFRKB_winged PF14465.1 CCC69070.1 - 0.004 16.9 0.3 0.013 15.2 0.2 1.9 1 0 0 1 1 1 1 NFRKB Winged Helix-like TFIID-31kDa PF02291.10 CCC69072.1 - 2e-51 173.1 0.0 3.2e-51 172.4 0.0 1.3 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit MBF1 PF08523.5 CCC69073.1 - 2.8e-27 94.5 1.7 2.8e-27 94.5 1.2 2.0 2 1 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 CCC69073.1 - 8.6e-14 51.1 0.3 1.4e-13 50.4 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.1 CCC69073.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 CCC69073.1 - 1.2e-05 25.2 0.1 1.9e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain LRR_6 PF13516.1 CCC69074.1 - 6.7e-15 53.4 13.0 0.061 13.4 0.1 8.5 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.2 CCC69074.1 - 6.8e-14 51.1 22.8 0.00058 19.4 1.0 5.9 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 CCC69074.1 - 1.1e-10 39.9 13.0 4.6 7.6 0.0 8.1 8 0 0 8 8 8 6 Leucine Rich Repeat LRR_8 PF13855.1 CCC69074.1 - 1.3e-08 34.4 16.4 0.0058 16.3 0.6 5.2 3 2 1 4 4 4 3 Leucine rich repeat LRR_7 PF13504.1 CCC69074.1 - 9.1e-06 25.0 14.2 29 5.4 0.0 7.9 7 0 0 7 7 7 1 Leucine rich repeat Cauli_VI PF01693.11 CCC69075.1 - 1.6e-26 92.0 6.0 3.2e-18 65.4 1.3 2.6 2 0 0 2 2 2 2 Caulimovirus viroplasmin RNase_H PF00075.19 CCC69075.1 - 5e-25 88.3 0.0 8.1e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 RNase H Ribosomal_L34e PF01199.13 CCC69075.1 - 0.12 12.6 0.0 8.3 6.7 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein L34e NTS_2 PF15448.1 CCC69075.1 - 0.35 11.2 0.1 0.35 11.2 0.1 2.9 2 1 1 3 3 3 0 N-terminal segments of P. falciparum erythrocyte membrane protein SWIB PF02201.13 CCC69076.1 - 1.3e-23 82.5 0.2 2.5e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 CCC69076.1 - 2.2e-12 46.5 0.1 6.1e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 DEK C terminal domain GAGA_bind PF06217.7 CCC69076.1 - 0.66 9.8 6.7 0.93 9.3 4.6 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family NARP1 PF12569.3 CCC69076.1 - 0.79 8.4 10.4 1 8.0 7.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BAR PF03114.13 CCC69077.1 - 0.13 11.7 6.0 0.11 12.0 2.3 2.2 2 1 0 2 2 2 0 BAR domain VPS11_C PF12451.3 CCC69078.1 - 1.1e-05 25.1 0.1 1.1e-05 25.1 0.0 2.7 3 0 0 3 3 3 1 Vacuolar protein sorting protein 11 C terminal zf-C3HC4_2 PF13923.1 CCC69078.1 - 0.00053 19.9 4.5 0.0015 18.5 3.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCC69078.1 - 0.00067 19.4 4.5 0.002 17.9 3.1 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCC69078.1 - 0.00097 18.8 5.0 0.0029 17.3 3.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCC69078.1 - 0.0017 18.1 3.7 0.0048 16.6 2.5 1.9 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.24 CCC69078.1 - 0.012 15.2 3.4 0.027 14.1 2.4 1.6 1 0 0 1 1 1 0 PHD-finger zf-C3HC4 PF00097.20 CCC69078.1 - 0.019 14.6 3.8 0.048 13.3 2.7 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCC69078.1 - 0.11 12.2 1.2 0.33 10.6 0.8 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 CCC69078.1 - 0.18 11.9 2.2 0.42 10.7 1.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-Apc11 PF12861.2 CCC69078.1 - 0.22 11.3 1.0 0.44 10.4 0.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 CCC69078.1 - 0.52 10.0 3.1 0.28 10.9 0.3 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 S10_plectin PF03501.10 CCC69079.1 - 2e-42 142.9 0.9 2.4e-42 142.7 0.6 1.0 1 0 0 1 1 1 1 Plectin/S10 domain DUF505 PF04458.7 CCC69079.1 - 0.01 14.0 0.5 0.012 13.7 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF505) PadR PF03551.9 CCC69079.1 - 0.021 14.5 0.3 0.021 14.5 0.2 1.9 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family YjcQ PF09639.5 CCC69079.1 - 0.022 14.8 0.3 0.035 14.2 0.2 1.3 1 0 0 1 1 1 0 YjcQ protein HTH_45 PF14947.1 CCC69079.1 - 0.028 14.2 0.3 0.051 13.4 0.2 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DUF1975 PF09318.5 CCC69079.1 - 0.054 13.0 3.8 0.058 13.0 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1975) DUF2977 PF11192.3 CCC69079.1 - 0.44 10.4 1.9 0.49 10.2 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2977) S1 PF00575.18 CCC69080.1 - 2.5e-51 171.6 34.0 1.2e-13 50.9 0.3 12.8 11 2 1 12 12 12 8 S1 RNA binding domain TPR_16 PF13432.1 CCC69080.1 - 4.1e-06 27.3 0.0 0.34 11.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCC69080.1 - 1.3e-05 25.4 0.0 0.25 11.7 0.0 3.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCC69080.1 - 2.8e-05 24.3 0.0 0.68 10.7 0.0 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat Suf PF05843.9 CCC69080.1 - 3.3e-05 23.7 26.2 0.00026 20.8 2.9 4.6 3 1 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_15 PF13429.1 CCC69080.1 - 0.012 14.6 0.9 0.059 12.4 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCC69080.1 - 0.028 14.3 0.0 10 6.1 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_3 PF07720.7 CCC69080.1 - 0.083 12.7 0.1 0.52 10.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RrnaAD PF00398.15 CCC69081.1 - 6.4e-59 199.1 0.2 7.9e-59 198.8 0.2 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase TAFII55_N PF04658.8 CCC69082.1 - 4e-55 185.7 0.2 4e-55 185.7 0.1 2.8 3 0 0 3 3 3 1 TAFII55 protein conserved region SNF2_N PF00176.18 CCC69083.1 - 3.5e-84 282.1 1.3 6.5e-84 281.2 0.9 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCC69083.1 - 2.3e-16 59.3 0.1 2.6e-15 56.0 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.20 CCC69083.1 - 3.2e-16 59.0 0.6 9e-16 57.5 0.4 1.8 1 0 0 1 1 1 1 Bromodomain SnAC PF14619.1 CCC69083.1 - 9.2e-16 57.7 2.4 9.2e-16 57.7 1.7 3.6 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 CCC69083.1 - 7.6e-11 41.2 1.3 7.6e-11 41.2 0.9 2.1 2 0 0 2 2 2 1 QLQ VIT1 PF01988.14 CCC69083.1 - 0.21 11.0 0.1 0.63 9.4 0.1 1.8 1 0 0 1 1 1 0 VIT family HSA PF07529.8 CCC69083.1 - 3.9 7.3 12.6 0.048 13.4 1.9 3.1 3 0 0 3 3 3 0 HSA MFS_1 PF07690.11 CCC69084.1 - 1.9e-11 43.2 30.7 2.6e-11 42.8 19.3 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily FSH1 PF03959.8 CCC69085.1 - 9.7e-60 201.6 0.0 1.1e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CCC69085.1 - 1.3e-12 47.7 0.0 1.5e-12 47.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCC69085.1 - 3.9e-09 36.7 0.0 2.7e-05 24.1 0.0 2.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 CCC69085.1 - 0.00021 20.7 0.0 0.0011 18.4 0.0 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Esterase_phd PF10503.4 CCC69085.1 - 0.15 11.2 0.0 2.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Esterase PHB depolymerase Mre11_DNA_bind PF04152.9 CCC69086.1 - 1.2e-52 178.2 0.2 2.7e-52 177.1 0.2 1.6 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 CCC69086.1 - 9.1e-26 90.4 2.1 1.4e-25 89.9 1.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCC69086.1 - 0.00096 19.0 0.0 0.0029 17.4 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain MRP_L53 PF10780.4 CCC69087.1 - 3.6e-19 68.4 0.1 6.6e-19 67.6 0.1 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 adh_short PF00106.20 CCC69088.1 - 5.9e-30 104.3 0.0 7.6e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCC69088.1 - 2.8e-13 50.2 0.0 3.5e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCC69088.1 - 1.5e-08 34.5 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 CCC69088.1 - 0.0085 15.8 0.0 0.017 14.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 CCC69088.1 - 0.017 14.6 0.0 0.031 13.7 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GHMP_kinases_N PF00288.21 CCC69090.1 - 2.3e-14 53.1 1.6 1.2e-13 50.9 0.4 2.4 2 1 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCC69090.1 - 3.7e-05 23.8 0.0 7.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal TRAPPC10 PF12584.3 CCC69092.1 - 5.8e-16 58.3 0.0 1.1e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Prefoldin_3 PF13758.1 CCC69092.1 - 0.058 13.1 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 Prefoldin subunit Foie-gras_1 PF11817.3 CCC69092.1 - 0.095 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Foie gras liver health family 1 Pkinase PF00069.20 CCC69093.1 - 1.7e-42 145.4 1.0 1.7e-22 79.8 0.4 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69093.1 - 1.2e-11 44.2 1.1 4.2e-08 32.5 0.2 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Glyco_hydro_72 PF03198.9 CCC69094.1 - 1.1e-126 422.1 4.7 1.6e-126 421.5 3.3 1.2 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 CCC69094.1 - 1.8e-06 27.0 0.0 3.5e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 CCC69094.1 - 0.00057 19.1 0.1 0.0031 16.7 0.1 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) HGTP_anticodon PF03129.15 CCC69094.1 - 0.083 12.8 0.0 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Anticodon binding domain DUF1117 PF06547.7 CCC69094.1 - 1.7 8.7 5.4 4.8 7.3 3.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) Tmemb_cc2 PF10267.4 CCC69094.1 - 3.7 6.0 5.9 5.8 5.4 4.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Myb_DNA-binding PF00249.26 CCC69095.1 - 3.3e-20 71.8 4.8 5.5e-10 39.1 0.2 3.3 4 0 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCC69095.1 - 1.7e-18 66.4 2.8 6.8e-13 48.5 0.6 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain MCM_N PF14551.1 CCC69095.1 - 0.044 14.2 2.8 0.94 9.9 0.1 2.9 3 0 0 3 3 3 0 MCM N-terminal domain RICH PF05062.7 CCC69095.1 - 0.075 13.1 9.6 0.026 14.6 3.9 2.4 2 0 0 2 2 2 0 RICH domain Tubulin_3 PF14881.1 CCC69097.1 - 5e-26 91.2 0.1 1.1e-25 90.1 0.1 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CCC69097.1 - 1.1e-17 64.1 0.2 3e-17 62.7 0.1 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 CCC69097.1 - 6.8e-05 22.7 0.0 0.00029 20.7 0.0 2.0 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Abhydrolase_1 PF00561.15 CCC69098.1 - 2.1e-12 47.0 0.0 3.7e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 CCC69098.1 - 6.8e-11 42.4 0.0 1.3e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCC69098.1 - 1.3e-06 28.1 0.0 3.5e-06 26.8 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF915 PF06028.6 CCC69098.1 - 0.00011 21.4 0.1 0.00018 20.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Cutinase PF01083.17 CCC69098.1 - 0.0011 18.7 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Cutinase Lipase_3 PF01764.20 CCC69098.1 - 0.003 17.1 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF4375 PF14300.1 CCC69098.1 - 0.0089 16.0 0.0 1.8 8.5 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4375) VirJ PF06057.6 CCC69098.1 - 0.024 14.4 0.0 0.058 13.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) N2227 PF07942.7 CCC69099.1 - 8.7e-64 215.0 0.7 1.5e-63 214.2 0.5 1.4 1 0 0 1 1 1 1 N2227-like protein GHMP_kinases_N PF00288.21 CCC69100.1 - 6.8e-20 70.9 0.2 1.4e-19 69.9 0.1 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCC69100.1 - 8.3e-05 22.7 0.0 0.00018 21.6 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Pkinase PF00069.20 CCC69101.1 - 4.2e-53 180.1 1.8 5.9e-53 179.6 0.1 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69101.1 - 7.3e-25 87.5 0.0 1.5e-24 86.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase MitMem_reg PF13012.1 CCC69102.1 - 1.6e-40 137.7 1.5 3.1e-40 136.8 0.3 2.0 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 CCC69102.1 - 1.6e-28 98.6 0.1 3.3e-28 97.7 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UbiA PF01040.13 CCC69103.1 - 3.3e-24 85.5 12.8 4.2e-24 85.1 8.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family KOW PF00467.24 CCC69104.1 - 0.18 11.5 3.5 0.11 12.2 1.1 1.7 2 0 0 2 2 2 0 KOW motif EF-hand_1 PF00036.27 CCC69105.1 - 4.9e-23 78.6 16.0 1.8e-07 29.9 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCC69105.1 - 1.1e-22 79.9 14.7 2.3e-13 50.0 1.9 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCC69105.1 - 5.9e-19 66.1 15.6 7.5e-07 28.5 0.1 4.4 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.1 CCC69105.1 - 3.1e-17 61.9 15.5 1.5e-10 40.4 0.7 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CCC69105.1 - 6.9e-12 44.1 17.3 3.6e-06 26.0 0.0 4.2 4 1 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CCC69105.1 - 5.2e-09 35.8 0.4 0.00011 22.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 CCC69105.1 - 1.5e-05 24.6 4.2 0.0035 17.0 0.1 2.3 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand MgtE_N PF03448.12 CCC69105.1 - 0.015 15.6 4.7 0.051 13.8 0.5 2.7 3 0 0 3 3 3 0 MgtE intracellular N domain VCBS PF13517.1 CCC69105.1 - 0.033 14.5 0.0 0.29 11.5 0.0 2.2 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Caleosin PF05042.8 CCC69105.1 - 0.049 13.1 0.0 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.4 CCC69105.1 - 0.065 13.2 5.4 1.7 8.6 0.4 2.2 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Ribosomal_L11 PF00298.14 CCC69105.1 - 0.1 12.7 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11, RNA binding domain EF-hand_like PF09279.6 CCC69105.1 - 0.12 12.4 3.9 0.63 10.0 0.3 2.6 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like CAP_GLY PF01302.20 CCC69106.1 - 1.9e-19 69.1 1.6 3.4e-19 68.2 1.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain CENP-F_leu_zip PF10473.4 CCC69106.1 - 0.0085 15.9 18.0 0.0085 15.9 12.5 5.9 3 2 5 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PIGA PF08288.7 CCC69107.1 - 2.7e-43 146.2 2.2 2.7e-43 146.2 1.5 2.1 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 CCC69107.1 - 1.2e-27 96.3 0.0 2e-27 95.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCC69107.1 - 7.4e-21 74.6 2.0 1.4e-20 73.7 1.4 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 CCC69107.1 - 2.6e-18 66.6 0.0 4.8e-18 65.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 CCC69107.1 - 5e-12 46.1 0.0 1.4e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_2 PF13477.1 CCC69107.1 - 4.3e-05 23.3 0.3 0.0001 22.1 0.2 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 CCC69107.1 - 0.0094 16.2 0.0 0.023 14.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 CCC69107.1 - 0.17 11.3 1.3 0.83 9.0 0.0 2.3 1 1 1 2 2 2 0 Starch synthase catalytic domain TFR_dimer PF04253.10 CCC69108.1 - 6.9e-35 119.3 0.0 1.2e-34 118.5 0.0 1.4 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 CCC69108.1 - 0.00074 19.1 0.0 0.0024 17.5 0.0 1.8 2 0 0 2 2 2 1 PA domain Peptidase_M28 PF04389.12 CCC69108.1 - 0.018 14.8 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M28 Cyt-b5 PF00173.23 CCC69109.1 - 2.1e-12 46.6 0.0 3.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PH_BEACH PF14844.1 CCC69110.1 - 0.17 11.7 0.2 0.17 11.7 0.1 1.9 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH TAP_C PF03943.8 CCC69111.1 - 3.7e-16 58.2 0.0 9.3e-16 56.9 0.0 1.7 1 0 0 1 1 1 1 TAP C-terminal domain LRR_9 PF14580.1 CCC69111.1 - 2.7e-06 27.0 0.7 5.1e-06 26.1 0.5 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 CCC69111.1 - 8e-06 25.3 6.2 0.00014 21.4 0.6 3.4 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 CCC69111.1 - 0.00081 19.2 1.8 2.3 8.5 0.1 3.8 3 0 0 3 3 3 2 Leucine Rich repeat NTF2 PF02136.15 CCC69111.1 - 0.0043 17.4 0.5 0.56 10.6 0.3 3.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_7 PF13504.1 CCC69111.1 - 1.4 9.4 5.8 14 6.4 0.4 4.4 3 1 1 4 4 4 0 Leucine rich repeat Sec63 PF02889.11 CCC69112.1 - 1.7e-18 66.9 0.1 1.8e-16 60.2 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 CCC69112.1 - 6.6e-18 64.1 0.4 1.7e-17 62.8 0.3 1.8 1 0 0 1 1 1 1 DnaJ domain Sporozoite_P67 PF05642.6 CCC69112.1 - 0.029 12.2 1.0 0.056 11.3 0.7 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Acetyltransf_1 PF00583.19 CCC69113.1 - 5.7e-12 45.4 0.0 8.4e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCC69113.1 - 6.4e-07 29.4 0.1 1.3e-06 28.4 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCC69113.1 - 1.7e-05 24.8 0.0 3.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 CCC69113.1 - 0.00031 20.6 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 CCC69113.1 - 0.0021 18.1 0.0 0.003 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCC69113.1 - 0.05 13.3 0.0 0.081 12.6 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein FolB PF02152.13 CCC69114.1 - 0.017 15.2 0.2 0.09 12.9 0.1 2.2 2 0 0 2 2 2 0 Dihydroneopterin aldolase DNA_pol_B PF00136.16 CCC69115.1 - 6.4e-97 325.2 2.8 1.3e-96 324.2 2.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 CCC69115.1 - 2.1e-19 69.5 10.5 7.4e-10 38.1 1.4 3.1 3 1 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 CCC69115.1 - 9.5e-11 41.5 6.1 2.4e-10 40.2 4.3 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DCR PF14047.1 CCC69115.1 - 0.034 14.4 0.1 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 Dppa2/4 conserved region HypA PF01155.14 CCC69115.1 - 0.82 9.3 3.1 3.3 7.4 0.2 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family CENP-Q PF13094.1 CCC69116.1 - 2.1 8.3 8.0 3.7 7.5 5.5 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SET PF00856.23 CCC69117.1 - 3.6e-08 33.8 0.1 8.4e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 SET domain YHS PF04945.8 CCC69117.1 - 0.0062 16.3 0.3 0.024 14.5 0.2 2.0 1 0 0 1 1 1 1 YHS domain HATPase_c_3 PF13589.1 CCC69118.1 - 3e-10 39.8 0.1 5.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 CCC69118.1 - 5.4e-10 39.0 0.1 9.8e-09 34.9 0.1 2.3 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 CCC69118.1 - 1.7e-06 27.7 0.0 3.3e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF3661 PF12400.3 CCC69120.1 - 3.5e-45 153.2 5.4 3.5e-45 153.2 3.7 2.5 3 0 0 3 3 3 1 Vaculolar membrane protein DUF2208 PF09973.4 CCC69120.1 - 0.16 11.1 2.3 0.92 8.7 0.3 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) Pet20 PF08692.5 CCC69121.1 - 2.2e-24 85.9 6.4 1.1e-23 83.6 0.9 2.9 2 1 0 2 2 2 1 Mitochondrial protein Pet20 Methyltransf_15 PF09445.5 CCC69123.1 - 1.6e-61 206.6 0.1 2.9e-61 205.8 0.1 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase UPF0020 PF01170.13 CCC69123.1 - 5.7e-10 39.0 0.0 1e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CCC69123.1 - 1.4e-08 34.8 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC69123.1 - 1.7e-08 34.1 0.1 3.6e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC69123.1 - 2.9e-05 24.3 0.0 7e-05 23.1 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC69123.1 - 0.00012 22.6 0.0 0.00018 22.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CCC69123.1 - 0.0015 18.0 2.7 0.0079 15.6 0.0 2.7 1 1 1 2 2 2 1 DNA methylase MethyltransfD12 PF02086.10 CCC69123.1 - 0.0046 16.4 0.5 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 D12 class N6 adenine-specific DNA methyltransferase MTS PF05175.9 CCC69123.1 - 0.013 14.8 0.0 0.031 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain tRNA_U5-meth_tr PF05958.6 CCC69123.1 - 0.015 14.0 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase VTC PF09359.5 CCC69123.1 - 0.024 13.6 1.7 0.024 13.6 1.2 1.7 2 0 0 2 2 2 0 VTC domain Methyltransf_23 PF13489.1 CCC69123.1 - 0.046 13.4 0.0 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CBF PF03914.12 CCC69123.1 - 0.22 10.9 1.4 1.4 8.3 1.0 2.1 1 1 0 1 1 1 0 CBF/Mak21 family BCA_ABC_TP_C PF12399.3 CCC69124.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Branched-chain amino acid ATP-binding cassette transporter Kinesin PF00225.18 CCC69125.1 - 4.5e-104 347.7 0.1 6.7e-104 347.2 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Lectin_N PF03954.9 CCC69125.1 - 0.0093 15.3 6.4 0.44 9.9 0.5 2.5 2 1 0 2 2 2 2 Hepatic lectin, N-terminal domain GTP-bdg_N PF13167.1 CCC69125.1 - 0.032 14.3 0.0 0.089 12.9 0.0 1.7 1 0 0 1 1 1 0 GTP-binding GTPase N-terminal UPF0227 PF05728.7 CCC69125.1 - 0.12 12.0 0.2 10 5.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Het-C PF07217.6 CCC69125.1 - 0.2 9.8 2.9 0.069 11.3 0.2 1.4 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C Fib_alpha PF08702.5 CCC69125.1 - 1.6 8.8 11.0 2 8.5 0.7 3.1 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family IncA PF04156.9 CCC69125.1 - 1.8 8.1 9.4 1 8.9 3.6 2.2 2 0 0 2 2 2 0 IncA protein Asp PF00026.18 CCC69126.1 - 1.3e-107 359.7 0.0 1.6e-107 359.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCC69126.1 - 7.5e-11 42.2 0.0 1.3e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 CCC69126.1 - 3e-05 24.4 0.1 0.0053 17.2 0.0 2.9 3 0 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 CCC69126.1 - 0.00014 21.4 0.0 0.0016 18.0 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Pkinase PF00069.20 CCC69127.1 - 8.3e-79 264.3 0.0 1.4e-78 263.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69127.1 - 3.8e-39 134.3 0.0 8.7e-39 133.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CCC69127.1 - 1.5e-24 85.8 1.4 1.9e-12 47.1 0.1 2.9 2 0 0 2 2 2 2 FHA domain Kinase-like PF14531.1 CCC69127.1 - 1.4e-08 34.1 0.0 2.5e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCC69127.1 - 3.9e-05 22.8 0.0 7.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC69127.1 - 0.00015 21.6 0.0 0.012 15.3 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 CCC69127.1 - 0.0074 15.6 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Mei5 PF10376.4 CCC69128.1 - 1e-28 100.3 26.7 1.8e-28 99.6 18.3 1.4 1 1 0 1 1 1 1 Double-strand recombination repair protein Tfb2 PF03849.9 CCC69129.1 - 7.2e-155 515.1 1.7 1.1e-154 514.5 1.2 1.2 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 CCC69129.1 - 1.5e-06 27.9 0.1 6.4e-06 25.9 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Ribonuclease_T2 PF00445.13 CCC69130.1 - 3.8e-39 134.2 0.4 6.3e-39 133.5 0.3 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family CENP-F_leu_zip PF10473.4 CCC69131.1 - 0.0065 16.3 4.6 0.0065 16.3 3.2 1.9 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MalF_P2 PF14785.1 CCC69131.1 - 0.019 14.8 0.6 0.033 14.0 0.4 1.3 1 0 0 1 1 1 0 Maltose transport system permease protein MalF P2 domain MAD PF05557.8 CCC69131.1 - 0.029 12.4 8.5 0.0074 14.4 3.8 1.4 2 0 0 2 2 2 0 Mitotic checkpoint protein V_ATPase_I PF01496.14 CCC69131.1 - 0.031 12.1 0.5 0.041 11.7 0.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 CCC69131.1 - 0.24 10.9 0.9 0.54 9.8 0.1 1.8 2 0 0 2 2 2 0 IncA protein Pox_A3L PF05288.6 CCC69131.1 - 0.25 11.1 2.6 0.54 10.0 1.8 1.5 1 0 0 1 1 1 0 Poxvirus A3L Protein DUF972 PF06156.8 CCC69131.1 - 0.29 11.5 3.0 0.67 10.3 2.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Y_phosphatase PF00102.22 CCC69132.1 - 2.9e-57 193.7 3.7 6.7e-52 176.1 0.8 2.5 2 0 0 2 2 2 2 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 CCC69132.1 - 0.00099 19.3 0.0 0.0034 17.6 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 CCC69132.1 - 0.0037 16.8 0.0 0.028 13.9 0.0 2.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 CCC69132.1 - 0.034 14.1 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate IBN_N PF03810.14 CCC69133.1 - 3.3e-15 55.7 0.3 1.3e-14 53.8 0.2 2.1 1 0 0 1 1 1 1 Importin-beta N-terminal domain Mog1 PF04603.7 CCC69133.1 - 0.037 13.9 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 Ran-interacting Mog1 protein NAPRTase PF04095.11 CCC69134.1 - 7.2e-69 231.7 0.2 9.1e-69 231.4 0.1 1.1 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family WD40 PF00400.27 CCC69135.1 - 1.9e-06 27.5 1.8 0.00078 19.2 0.0 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Linker_histone PF00538.14 CCC69136.1 - 4.1e-43 145.3 9.7 3.8e-22 78.1 0.4 2.9 3 0 0 3 3 3 2 linker histone H1 and H5 family Pex19 PF04614.7 CCC69136.1 - 1.1 8.8 6.5 1 8.9 0.5 2.1 2 0 0 2 2 2 0 Pex19 protein family FliE PF02049.13 CCC69136.1 - 2 8.5 6.7 0.77 9.8 0.1 3.0 2 2 2 4 4 4 0 Flagellar hook-basal body complex protein FliE Mucin PF01456.12 CCC69136.1 - 5.3 6.8 13.3 0.41 10.4 3.9 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein TRF PF08558.5 CCC69137.1 - 4.9e-74 248.6 0.0 7.3e-74 248.1 0.0 1.2 1 0 0 1 1 1 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 CCC69137.1 - 1.7e-07 31.2 0.3 3.2e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCC69137.1 - 0.00078 19.5 0.1 0.0021 18.0 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain YEATS PF03366.11 CCC69138.1 - 1.3e-24 85.7 0.2 2e-24 85.1 0.1 1.3 1 0 0 1 1 1 1 YEATS family Mucin PF01456.12 CCC69139.1 - 0.005 16.6 8.8 0.005 16.6 6.1 1.5 2 0 0 2 2 2 1 Mucin-like glycoprotein SSP160 PF06933.6 CCC69139.1 - 0.9 7.4 11.5 1.2 7.0 8.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Sporozoite_P67 PF05642.6 CCC69139.1 - 6.9 4.4 15.0 25 2.5 10.4 1.7 1 1 0 1 1 1 0 Sporozoite P67 surface antigen CDC45 PF02724.9 CCC69139.1 - 8.2 4.3 11.5 10 4.0 8.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DPPIV_N PF00930.16 CCC69140.1 - 1.5e-84 283.6 0.6 2.2e-84 283.0 0.4 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 CCC69140.1 - 5e-49 166.4 0.5 8e-49 165.7 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 CCC69140.1 - 2.9e-08 33.5 0.0 5.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCC69140.1 - 0.0001 22.3 0.0 0.0019 18.1 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 CCC69140.1 - 0.0012 17.1 0.0 0.0026 16.1 0.0 1.5 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_2 PF02230.11 CCC69140.1 - 0.0053 16.2 0.1 0.5 9.7 0.1 2.3 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Esterase PF00756.15 CCC69140.1 - 0.012 15.0 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 CCC69140.1 - 0.017 14.7 0.1 0.28 10.6 0.0 2.4 1 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 CCC69140.1 - 0.1 11.9 0.9 0.7 9.2 0.2 2.2 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) OAD_gamma PF04277.8 CCC69140.1 - 0.23 11.8 0.0 0.45 10.9 0.0 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Ribosomal_L18p PF00861.17 CCC69141.1 - 2.7e-46 156.6 1.5 3.3e-46 156.3 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 CCC69141.1 - 1.6e-32 111.8 2.1 1.6e-32 111.8 1.4 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 CCC69141.1 - 0.023 14.7 0.4 1.5 8.8 0.0 2.8 3 0 0 3 3 3 0 Threonine synthase N terminus CtaG_Cox11 PF04442.9 CCC69142.1 - 3.2e-58 195.8 0.0 5.9e-58 194.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 Zn_clus PF00172.13 CCC69143.1 - 2e-06 27.6 9.5 4.4e-06 26.5 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 CCC69143.1 - 0.34 10.2 10.3 0.39 10.0 7.2 1.1 1 0 0 1 1 1 0 Vta1 like NifU_N PF01592.11 CCC69144.1 - 1.9e-52 176.5 0.1 2.2e-52 176.3 0.1 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain LRR_4 PF12799.2 CCC69145.1 - 0.00088 18.8 13.0 0.0014 18.2 1.9 4.7 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) PHD PF00628.24 CCC69146.1 - 3.5e-12 45.8 5.4 8.1e-12 44.6 3.7 1.7 1 0 0 1 1 1 1 PHD-finger Response_reg PF00072.19 CCC69146.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Response regulator receiver domain Bunya_NS-S PF01104.12 CCC69146.1 - 0.019 14.4 0.2 0.033 13.6 0.1 1.3 1 0 0 1 1 1 0 Bunyavirus non-structural protein NS-s zf-RING_2 PF13639.1 CCC69146.1 - 1.4 8.7 6.2 5 7.0 4.3 2.0 1 0 0 1 1 1 0 Ring finger domain WD40 PF00400.27 CCC69147.1 - 2.1e-05 24.2 5.0 0.19 11.6 0.2 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat Rrn6 PF10214.4 CCC69147.1 - 0.0021 16.2 1.1 0.027 12.6 0.0 2.2 1 1 1 2 2 2 2 RNA polymerase I-specific transcription-initiation factor CAF1C_H4-bd PF12265.3 CCC69147.1 - 0.017 14.9 0.3 0.043 13.7 0.2 1.7 1 0 0 1 1 1 0 Histone-binding protein RBBP4 or subunit C of CAF1 complex Pkinase PF00069.20 CCC69148.1 - 1.1e-67 227.8 0.0 1.9e-67 227.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69148.1 - 8.8e-37 126.5 0.0 1.9e-36 125.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC69148.1 - 5.9e-10 38.5 0.0 1.1e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCC69148.1 - 0.0019 17.2 0.0 0.0031 16.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC69148.1 - 0.023 14.4 0.0 0.096 12.4 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 CCC69149.1 - 4.6e-64 216.0 0.0 8.6e-64 215.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69149.1 - 8.5e-37 126.6 0.0 1.4e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC69149.1 - 3.9e-08 32.5 0.0 7e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCC69149.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 CCC69149.1 - 0.044 13.1 0.1 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 CCC69149.1 - 0.17 10.8 0.2 0.51 9.3 0.2 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L35Ae PF01247.13 CCC69150.1 - 1.8e-41 139.8 1.0 2e-41 139.6 0.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 CCC69150.1 - 0.008 16.0 0.0 3.6 7.5 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain Oxysterol_BP PF01237.13 CCC69151.1 - 1.6e-92 309.7 0.2 1.8e-92 309.5 0.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DUF2971 PF11185.3 CCC69151.1 - 0.037 14.7 0.1 0.12 13.0 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2971) Nop53 PF07767.6 CCC69152.1 - 1.8e-86 290.5 59.2 2.9e-86 289.8 41.0 1.3 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) DUF3439 PF11921.3 CCC69152.1 - 0.0041 16.8 4.6 0.0084 15.8 3.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Ndc1_Nup PF09531.5 CCC69152.1 - 1.1 7.6 8.5 2.3 6.5 5.9 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ACPS PF01648.15 CCC69153.1 - 9.4e-14 51.2 0.0 1.6e-13 50.4 0.0 1.4 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily APG5 PF04106.7 CCC69155.1 - 4.2e-37 127.5 0.2 5.4e-37 127.1 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 SGT1 PF07093.6 CCC69156.1 - 3.3e-37 128.1 17.7 6.2e-34 117.3 0.0 2.1 1 1 0 2 2 2 2 SGT1 protein Plasmid_parti PF01672.11 CCC69156.1 - 0.052 13.9 1.8 0.096 13.1 0.2 2.3 2 0 0 2 2 2 0 Putative plasmid partition protein WD40 PF00400.27 CCC69158.1 - 2.9e-45 150.5 19.8 4.9e-09 35.7 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 CCC69158.1 - 0.00025 19.9 1.6 0.33 9.6 0.0 4.4 1 1 2 3 3 3 2 Nup133 N terminal like DUF1258 PF06869.7 CCC69158.1 - 0.0035 16.4 0.1 0.0071 15.4 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) PQQ_2 PF13360.1 CCC69158.1 - 0.012 15.1 0.4 0.79 9.1 0.0 2.6 2 1 1 3 3 3 0 PQQ-like domain PTPA PF03095.10 CCC69159.1 - 2.8e-116 387.9 0.2 3.2e-116 387.7 0.2 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein F_actin_bind PF08919.5 CCC69159.1 - 0.06 13.0 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 F-actin binding EXS PF03124.9 CCC69160.1 - 1.3e-91 307.1 24.4 1.8e-91 306.7 16.9 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.14 CCC69160.1 - 5.3e-39 134.6 13.4 8.1e-39 134.0 9.3 1.3 1 0 0 1 1 1 1 SPX domain APG6 PF04111.7 CCC69161.1 - 7.9e-99 330.6 12.1 1.3e-98 329.9 8.4 1.4 1 0 0 1 1 1 1 Autophagy protein Apg6 Ax_dynein_light PF10211.4 CCC69161.1 - 0.0011 18.8 10.2 0.0011 18.8 7.1 2.5 3 0 0 3 3 3 1 Axonemal dynein light chain DEAD PF00270.24 CCC69162.1 - 9.3e-47 158.6 0.0 3.7e-45 153.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC69162.1 - 2.7e-28 97.6 0.2 8.1e-28 96.1 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC69162.1 - 0.0028 17.4 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CCC69162.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain CMS1 PF14617.1 CCC69162.1 - 0.18 10.8 0.4 0.38 9.7 0.0 1.6 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Gly_rich PF12810.2 CCC69162.1 - 1 8.9 60.4 0.94 9.0 15.3 2.3 2 0 0 2 2 2 0 Glycine rich protein Mit_ribos_Mrp51 PF11709.3 CCC69163.1 - 2e-77 260.5 2.8 2.5e-77 260.1 1.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit NUDIX PF00293.23 CCC69164.1 - 4.3e-28 97.6 0.0 5.9e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Peptidase_C14 PF00656.17 CCC69165.1 - 7.4e-64 215.8 0.0 9.5e-64 215.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Hist_deacetyl PF00850.14 CCC69166.1 - 1.1e-63 215.4 0.1 1.7e-63 214.8 0.1 1.3 1 0 0 1 1 1 1 Histone deacetylase domain RhoGAP PF00620.22 CCC69167.1 - 2.5e-34 118.0 0.1 7.2e-34 116.6 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 CCC69167.1 - 1.3e-06 28.5 1.0 1.3e-05 25.3 0.1 2.8 2 0 0 2 2 2 1 PH domain PX PF00787.19 CCC69167.1 - 3.7e-05 23.4 2.6 7.1e-05 22.5 0.7 2.3 2 0 0 2 2 2 1 PX domain TFIIA PF03153.8 CCC69168.1 - 2.5e-61 208.6 21.2 6e-35 121.8 8.0 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Polyhedrin PF00738.13 CCC69168.1 - 0.1 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Polyhedrin 2-Hacid_dh_C PF02826.14 CCC69169.1 - 7e-38 129.5 0.0 1.1e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 CCC69169.1 - 5.8e-05 23.0 0.0 0.00012 22.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 CCC69169.1 - 0.0053 16.1 0.0 0.0091 15.3 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain Semialdhyde_dh PF01118.19 CCC69169.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 CCC69169.1 - 0.044 14.2 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent PEX11 PF05648.9 CCC69170.1 - 3.9e-07 29.5 4.8 3.9e-07 29.5 3.3 1.9 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) DUF4508 PF14969.1 CCC69170.1 - 0.025 14.6 0.1 0.025 14.6 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4508) M PF02370.11 CCC69170.1 - 0.065 13.5 2.1 0.34 11.4 1.4 2.3 1 0 0 1 1 1 0 M protein repeat DUF3318 PF11780.3 CCC69170.1 - 0.18 11.3 1.0 14 5.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) Arginase PF00491.16 CCC69171.1 - 4.1e-73 246.0 0.0 4.7e-73 245.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family GDPD PF03009.12 CCC69172.1 - 8.9e-77 258.0 0.0 1.7e-76 257.1 0.0 1.5 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 CCC69172.1 - 1.5e-33 114.9 1.8 5.5e-18 65.0 0.2 4.1 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCC69172.1 - 1.9e-20 71.5 2.3 8.7e-08 31.6 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 CCC69172.1 - 2.1e-16 59.9 0.2 5.6e-09 36.2 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCC69172.1 - 1.5e-15 56.8 2.2 3.6e-09 36.5 0.2 4.0 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCC69172.1 - 3.7e-13 48.3 0.7 7.9e-05 22.5 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat NanE PF04131.9 CCC69172.1 - 0.0063 15.5 0.4 0.12 11.3 0.0 2.7 4 0 0 4 4 4 1 Putative N-acetylmannosamine-6-phosphate epimerase ABC1 PF03109.11 CCC69173.1 - 2.8e-23 82.1 0.0 5.9e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 CCC69173.1 - 0.037 13.3 0.6 0.082 12.2 0.1 1.7 2 0 0 2 2 2 0 RIO1 family Arf PF00025.16 CCC69174.1 - 6.1e-76 253.5 0.1 6.9e-76 253.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCC69174.1 - 7.2e-11 41.7 0.0 8.2e-11 41.5 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCC69174.1 - 7.4e-11 41.5 0.0 8.7e-11 41.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CCC69174.1 - 5.4e-10 38.8 0.0 6.6e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 CCC69174.1 - 1.2e-09 37.4 0.5 4e-06 25.7 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 CCC69174.1 - 7.1e-09 36.1 0.0 1e-08 35.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 CCC69174.1 - 1.7e-05 24.3 0.1 0.00029 20.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCC69174.1 - 0.00037 20.4 0.1 0.00053 19.9 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 CCC69174.1 - 0.00073 19.8 0.4 0.0029 17.9 0.3 1.8 1 1 0 1 1 1 1 ABC transporter ArgK PF03308.11 CCC69174.1 - 0.0056 15.4 0.7 0.26 10.0 0.1 2.7 2 1 0 2 2 2 1 ArgK protein cobW PF02492.14 CCC69174.1 - 0.084 12.3 0.5 4.5 6.6 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Oxidored-like PF09791.4 CCC69176.1 - 2.2e-25 87.8 2.8 4.1e-25 86.9 2.0 1.5 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal DUF2951 PF11166.3 CCC69176.1 - 6.8 6.6 7.5 0.58 10.0 1.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) HSP70 PF00012.15 CCC69177.1 - 8.2e-174 578.8 1.4 1e-173 578.5 0.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCC69177.1 - 4.7e-12 45.1 0.2 2.2e-11 42.9 0.1 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 CCC69177.1 - 1.5e-05 24.8 5.0 8.1e-05 22.4 0.4 3.2 2 2 0 2 2 2 1 Cell division protein FtsA GYF PF02213.11 CCC69178.1 - 1.7e-20 72.3 1.1 1.7e-20 72.3 0.8 1.8 2 0 0 2 2 2 1 GYF domain tRNA-synt_2 PF00152.15 CCC69179.1 - 1.1e-109 366.2 0.0 1.8e-109 365.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 CCC69179.1 - 1.6e-08 34.2 0.3 3.5e-08 33.2 0.2 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CCC69179.1 - 0.00025 20.6 0.1 0.018 14.6 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.15 CCC69179.1 - 0.0014 17.9 0.6 0.01 15.0 0.0 2.4 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) S4_2 PF13275.1 CCC69179.1 - 0.068 12.7 0.2 0.72 9.5 0.1 2.4 2 0 0 2 2 2 0 S4 domain Lactamase_B_2 PF12706.2 CCC69180.1 - 2e-32 112.3 0.1 2.9e-32 111.7 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CCC69180.1 - 8.8e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain WD40 PF00400.27 CCC69181.1 - 0.0013 18.5 0.0 0.016 15.0 0.1 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Peptidase_M56 PF05569.6 CCC69182.1 - 0.12 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 BlaR1 peptidase M56 Rad4 PF03835.10 CCC69183.1 - 1.6e-10 40.5 3.5 3.6e-10 39.4 2.3 1.6 1 1 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 CCC69183.1 - 3.7e-10 39.9 0.5 1.2e-09 38.3 0.1 1.9 2 0 0 2 2 2 1 Transglutaminase-like superfamily Zn_Tnp_IS1595 PF12760.2 CCC69183.1 - 6.3 6.6 8.6 18 5.2 5.2 2.2 1 1 1 2 2 2 0 Transposase zinc-ribbon domain Sec62 PF03839.11 CCC69184.1 - 5.7e-62 209.0 0.1 6.8e-62 208.8 0.1 1.0 1 0 0 1 1 1 1 Translocation protein Sec62 Baculo_11_kDa PF06143.6 CCC69184.1 - 6 6.3 6.6 22 4.4 2.4 2.5 2 0 0 2 2 2 0 Baculovirus 11 kDa family SLAC1 PF03595.12 CCC69185.1 - 3.1e-76 256.1 35.9 3.6e-76 255.9 24.9 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Pyr_redox_2 PF07992.9 CCC69186.1 - 4.8e-42 144.1 1.0 8.5e-42 143.3 0.7 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 CCC69186.1 - 5.4e-35 119.7 7.0 5.9e-35 119.6 0.3 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 CCC69186.1 - 3.4e-19 69.0 2.2 3.4e-19 69.0 1.6 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCC69186.1 - 1.4e-09 38.3 0.6 2e-07 31.2 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCC69186.1 - 1.3e-07 31.0 0.2 1.3e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 CCC69186.1 - 3.1e-05 23.5 2.0 0.00059 19.4 0.2 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.1 CCC69186.1 - 7.7e-05 21.7 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 CCC69186.1 - 8e-05 21.2 7.8 0.3 9.5 0.4 3.9 2 1 2 4 4 4 3 HI0933-like protein GIDA PF01134.17 CCC69186.1 - 0.00028 19.8 3.4 0.0043 15.9 0.6 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 CCC69186.1 - 0.0091 15.6 0.3 0.0091 15.6 0.2 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 CCC69186.1 - 0.015 14.6 0.9 0.035 13.4 0.6 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 CCC69186.1 - 0.019 14.1 1.5 1.3 8.1 0.0 3.1 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 CCC69186.1 - 0.068 13.4 0.3 9.6 6.5 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 CCC69186.1 - 0.08 11.9 2.0 6.8 5.6 0.1 2.5 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 CCC69186.1 - 1.7 7.4 14.3 0.029 13.2 0.6 3.1 3 1 1 4 4 4 0 FAD dependent oxidoreductase Thi4 PF01946.12 CCC69186.1 - 3.8 6.5 7.9 0.26 10.3 0.4 2.5 3 1 0 3 3 3 0 Thi4 family Ribosomal_S6e PF01092.14 CCC69187.1 - 1e-60 202.9 0.6 2e-60 202.0 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e SRF-TF PF00319.13 CCC69188.1 - 1.2e-23 82.0 0.0 2.3e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Aldo_ket_red PF00248.16 CCC69189.1 - 2.2e-60 203.9 0.0 2.5e-60 203.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.7 CCC69189.1 - 0.0051 16.2 0.0 0.011 15.1 0.0 1.5 2 0 0 2 2 2 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) DUF3686 PF12458.3 CCC69189.1 - 0.027 12.7 0.0 0.049 11.8 0.0 1.3 1 0 0 1 1 1 0 ATPase involved in DNA repair Ceramidase PF05875.7 CCC69190.1 - 7.2e-96 320.3 18.4 8.4e-96 320.1 12.8 1.0 1 0 0 1 1 1 1 Ceramidase DUF1056 PF06341.6 CCC69190.1 - 0.053 13.5 1.2 0.053 13.5 0.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1056) DUF1129 PF06570.6 CCC69190.1 - 1.1 8.4 11.3 0.28 10.4 2.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1129) Sec16_C PF12931.2 CCC69191.1 - 2.9e-82 276.6 0.1 5.1e-82 275.8 0.0 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 CCC69191.1 - 3.2e-19 69.0 0.1 1.5e-18 66.8 0.1 2.3 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region AAA PF00004.24 CCC69192.1 - 2.1e-33 115.3 0.0 4.6e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCC69192.1 - 9.1e-08 32.3 0.1 4.7e-07 30.0 0.0 2.2 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 CCC69192.1 - 2.9e-06 28.1 0.1 9.9e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CCC69192.1 - 3.3e-06 26.9 0.8 2.6e-05 24.0 0.5 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 CCC69192.1 - 4.3e-06 26.8 0.0 6.8e-05 22.9 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 CCC69192.1 - 0.00018 21.8 0.2 0.00068 19.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 CCC69192.1 - 0.00025 21.1 0.8 0.014 15.5 0.0 3.1 4 0 0 4 4 2 1 RNA helicase AAA_11 PF13086.1 CCC69192.1 - 0.00067 19.2 0.1 0.0022 17.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCC69192.1 - 0.00072 19.2 0.1 0.0037 17.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCC69192.1 - 0.001 18.7 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_24 PF13479.1 CCC69192.1 - 0.0017 17.9 0.0 0.0036 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 CCC69192.1 - 0.0024 16.9 0.0 0.0054 15.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA_23 PF13476.1 CCC69192.1 - 0.0026 18.1 1.5 0.0026 18.1 1.1 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.12 CCC69192.1 - 0.0033 16.8 0.0 0.009 15.4 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCC69192.1 - 0.0052 16.6 0.2 0.021 14.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain Rad51 PF08423.6 CCC69192.1 - 0.0061 15.4 0.1 0.9 8.3 0.0 2.2 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CCC69192.1 - 0.012 15.0 0.0 0.043 13.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 CCC69192.1 - 0.014 14.8 0.0 5.6 6.2 0.0 2.4 1 1 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 CCC69192.1 - 0.018 14.9 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CCC69192.1 - 0.018 15.0 0.1 0.15 12.1 0.0 2.6 1 1 0 1 1 1 0 Sigma-54 interaction domain UPF0079 PF02367.12 CCC69192.1 - 0.02 14.4 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF3887 PF13026.1 CCC69192.1 - 0.022 15.0 0.2 0.057 13.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) AAA_30 PF13604.1 CCC69192.1 - 0.039 13.5 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.9 CCC69192.1 - 0.048 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) T2SE PF00437.15 CCC69192.1 - 0.058 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.9 CCC69192.1 - 0.067 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 CCC69192.1 - 0.079 13.2 0.1 0.31 11.3 0.0 2.1 2 0 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.7 CCC69192.1 - 0.098 11.7 0.0 0.19 10.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 CCC69192.1 - 0.12 11.3 0.0 0.25 10.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF3535 PF12054.3 CCC69193.1 - 6.4e-148 493.0 0.1 7.8e-146 486.1 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF3535) SNF2_N PF00176.18 CCC69193.1 - 5e-79 265.1 0.0 9.5e-79 264.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCC69193.1 - 1.4e-13 50.4 0.0 4.9e-13 48.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 CCC69193.1 - 5.9e-12 44.6 4.4 0.066 13.3 0.0 8.4 8 0 0 8 8 8 2 HEAT repeat Vac14_Fab1_bd PF12755.2 CCC69193.1 - 5.6e-06 26.6 0.1 0.5 10.7 0.0 4.8 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCC69193.1 - 4.4e-05 23.8 1.6 74 4.0 0.0 7.7 8 0 0 8 8 8 0 HEAT-like repeat Ribosomal_S4 PF00163.14 CCC69194.1 - 5.4e-26 90.8 1.1 8.7e-26 90.1 0.8 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCC69194.1 - 6.1e-14 51.1 0.3 2.2e-13 49.3 0.2 2.0 1 0 0 1 1 1 1 S4 domain Ribosomal_L21e PF01157.13 CCC69195.1 - 1.3e-45 153.2 5.9 1.8e-45 152.8 3.5 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.4 CCC69195.1 - 0.0022 17.3 0.0 0.0027 17.1 0.0 1.1 1 0 0 1 1 1 1 Monopolin complex subunit LRS4 Mt_ATP-synt_B PF05405.9 CCC69196.1 - 6.2e-54 181.8 9.0 7.4e-54 181.6 6.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) SRX PF09201.5 CCC69196.1 - 0.0012 18.5 2.0 0.0017 18.0 1.4 1.3 1 0 0 1 1 1 1 SRX Gastrin PF00918.12 CCC69196.1 - 0.19 12.5 2.8 0.27 12.0 1.5 1.5 1 1 0 1 1 1 0 Gastrin/cholecystokinin family Mer2 PF09074.5 CCC69197.1 - 0.4 10.5 3.2 0.85 9.5 0.1 2.2 2 0 0 2 2 2 0 Mer2 GPI2 PF06432.6 CCC69198.1 - 1.9e-57 194.7 21.6 2.2e-57 194.5 15.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF1204 PF06721.6 CCC69198.1 - 0.068 12.4 0.1 0.09 12.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) GCR1_C PF12550.3 CCC69199.1 - 1.2e-21 76.3 1.2 1.2e-21 76.3 0.8 2.3 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes AAA PF00004.24 CCC69200.1 - 5.2e-39 133.4 0.6 1.5e-38 131.9 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCC69200.1 - 2.5e-06 26.7 0.0 4.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 CCC69200.1 - 3.4e-05 23.9 0.2 0.0043 17.2 0.1 3.1 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.5 CCC69200.1 - 7.5e-05 22.5 1.6 0.012 15.4 0.0 3.4 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.9 CCC69200.1 - 0.00013 21.9 0.0 0.00013 21.9 0.0 3.5 5 1 0 5 5 3 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 CCC69200.1 - 0.00015 20.6 0.0 0.00015 20.6 0.0 1.8 2 0 0 2 2 1 1 TIP49 C-terminus AAA_18 PF13238.1 CCC69200.1 - 0.00064 20.0 0.5 0.00064 20.0 0.3 4.2 2 2 0 2 2 1 1 AAA domain AAA_14 PF13173.1 CCC69200.1 - 0.0015 18.4 0.0 0.0077 16.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCC69200.1 - 0.0018 17.7 0.0 0.0061 15.9 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 CCC69200.1 - 0.002 18.9 0.0 0.002 18.9 0.0 3.4 2 2 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CCC69200.1 - 0.004 16.8 0.0 0.018 14.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCC69200.1 - 0.005 16.5 0.4 0.017 14.8 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 CCC69200.1 - 0.0074 15.7 0.2 0.52 9.6 0.1 2.4 1 1 1 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCC69200.1 - 0.02 14.0 0.0 0.047 12.8 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 CCC69200.1 - 0.037 13.9 4.6 0.046 13.7 0.1 3.2 2 1 1 3 3 3 0 AAA ATPase domain RNA_helicase PF00910.17 CCC69200.1 - 0.044 13.9 0.1 0.35 11.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 CCC69200.1 - 0.076 12.8 0.0 0.076 12.8 0.0 2.6 2 2 0 2 2 2 0 AAA domain UCH PF00443.24 CCC69201.1 - 6.3e-37 127.1 6.5 8.5e-37 126.7 4.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC69201.1 - 2.9e-12 46.6 5.1 6.2e-12 45.5 3.5 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase VPS9 PF02204.13 CCC69203.1 - 1.6e-15 56.9 1.3 5.1e-15 55.3 0.9 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain polyprenyl_synt PF00348.12 CCC69204.1 - 1.9e-39 135.0 0.0 2.5e-39 134.6 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Arrestin_C PF02752.17 CCC69207.1 - 1.8e-06 28.1 0.1 0.00022 21.3 0.0 2.8 2 2 1 3 3 3 3 Arrestin (or S-antigen), C-terminal domain VPS28 PF03997.7 CCC69209.1 - 7.1e-67 224.6 1.6 8.1e-67 224.4 1.1 1.0 1 0 0 1 1 1 1 VPS28 protein DUF3417 PF11897.3 CCC69209.1 - 0.02 14.8 0.4 0.051 13.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) DUF3890 PF13029.1 CCC69209.1 - 0.05 13.6 1.0 0.84 9.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3890) RVT_3 PF13456.1 CCC69209.1 - 0.071 12.9 0.1 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Reverse transcriptase-like POT1 PF02765.12 CCC69209.1 - 0.074 12.9 0.1 0.094 12.6 0.1 1.3 1 1 0 1 1 1 0 Telomeric single stranded DNA binding POT1/CDC13 DnaG_DnaB_bind PF08278.6 CCC69209.1 - 0.089 13.0 0.3 0.31 11.2 0.0 1.9 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding DUF1759 PF03564.10 CCC69209.1 - 0.11 12.2 5.2 0.31 10.8 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) Imm3 PF14425.1 CCC69209.1 - 0.38 10.7 2.9 0.37 10.7 0.1 2.2 2 1 0 2 2 2 0 Immunity protein Imm3 Pro_isomerase PF00160.16 CCC69210.1 - 4.3e-09 36.7 0.5 1.9e-08 34.6 0.0 2.1 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD NIF PF03031.13 CCC69211.1 - 3.9e-42 143.6 0.1 6.4e-42 142.9 0.1 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Aldedh PF00171.17 CCC69212.1 - 6.9e-175 581.8 0.0 7.9e-175 581.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCC69212.1 - 0.18 10.4 0.0 0.42 9.2 0.0 1.6 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Glutaredoxin PF00462.19 CCC69214.1 - 3e-18 65.5 0.0 6.6e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin Nit_Regul_Hom PF10126.4 CCC69214.1 - 0.14 11.9 0.0 3.7 7.3 0.0 2.1 1 1 1 2 2 2 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII ABC2_membrane PF01061.19 CCC69215.1 - 1.1e-65 220.7 50.1 7.5e-36 123.2 8.7 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CCC69215.1 - 4.8e-36 124.0 0.0 2e-17 63.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCC69215.1 - 3.9e-35 119.6 4.3 6.7e-31 106.0 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 CCC69215.1 - 1.3e-08 34.8 0.0 2.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 CCC69215.1 - 9.3e-07 28.1 0.1 0.00025 20.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 CCC69215.1 - 8.7e-06 25.2 0.2 0.0011 18.4 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 CCC69215.1 - 2.4e-05 23.8 0.0 0.015 14.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCC69215.1 - 0.00012 21.4 0.4 0.015 14.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CCC69215.1 - 0.00039 20.4 0.1 0.012 15.5 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 CCC69215.1 - 0.00042 20.4 0.0 0.036 14.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 CCC69215.1 - 0.00046 19.3 11.3 0.00046 19.3 7.8 2.9 2 1 0 2 2 2 1 ABC-2 family transporter protein SMC_N PF02463.14 CCC69215.1 - 0.00046 19.4 0.0 2.5 7.2 0.0 3.1 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 CCC69215.1 - 0.0006 18.9 0.0 1.2 8.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_17 PF13207.1 CCC69215.1 - 0.0013 19.4 0.0 0.031 15.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCC69215.1 - 0.0014 18.3 0.0 0.06 13.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain MMR_HSR1 PF01926.18 CCC69215.1 - 0.0021 18.0 0.0 1.6 8.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase UPF0079 PF02367.12 CCC69215.1 - 0.0025 17.4 1.1 0.017 14.7 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 CCC69215.1 - 0.0045 17.2 0.0 0.14 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CCC69215.1 - 0.005 16.8 0.0 0.079 12.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CCC69215.1 - 0.0075 15.9 0.1 14 5.3 0.0 3.2 3 0 0 3 3 3 0 NTPase RNA_helicase PF00910.17 CCC69215.1 - 0.0085 16.2 0.0 1.5 8.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_19 PF13245.1 CCC69215.1 - 0.01 15.5 0.3 0.2 11.4 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain Miro PF08477.8 CCC69215.1 - 0.032 14.7 0.0 15 6.1 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 CCC69215.1 - 0.06 12.9 0.5 2.5 7.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CCC69215.1 - 0.063 13.1 0.2 1.7 8.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 CCC69215.1 - 0.068 13.3 0.0 2.7 8.2 0.0 3.0 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.1 CCC69215.1 - 0.089 12.7 0.1 3.3 7.7 0.0 3.3 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 CCC69215.1 - 0.11 11.9 1.7 4.8 6.5 0.3 2.6 2 0 0 2 2 2 0 AAA-like domain PduV-EutP PF10662.4 CCC69215.1 - 0.12 11.8 0.9 1.2 8.6 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Retinin_C PF04527.7 CCC69215.1 - 0.25 11.3 0.0 0.49 10.4 0.0 1.5 1 0 0 1 1 1 0 Drosophila Retinin like protein Oxidored_FMN PF00724.15 CCC69216.1 - 1.8e-128 428.3 0.0 2.1e-128 428.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Gly_transf_sug PF04488.10 CCC69217.1 - 1.3e-20 73.7 0.1 6.6e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DinB PF05163.7 CCC69217.1 - 0.013 15.1 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 DinB family TcdA_TcdB PF12919.2 CCC69217.1 - 0.022 13.2 5.7 1 7.7 0.2 2.3 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Lge1 PF11488.3 CCC69218.1 - 6.2e-15 55.1 0.4 9.6e-15 54.5 0.3 1.2 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 Mito_fiss_reg PF05308.6 CCC69218.1 - 0.0026 17.1 0.4 0.0035 16.7 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial fission regulator Beta-Casp PF10996.3 CCC69218.1 - 0.011 15.6 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Beta-Casp domain CAP_N PF01213.14 CCC69218.1 - 0.11 11.7 0.7 0.14 11.4 0.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-CCCH PF00642.19 CCC69219.1 - 7.7e-10 38.2 11.1 8e-06 25.4 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 CCC69219.1 - 0.032 14.2 18.8 0.23 11.5 3.7 2.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Glyco_transf_15 PF01793.11 CCC69220.1 - 7.4e-96 320.9 13.0 9.5e-96 320.6 9.0 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PTRF_SDPR PF15237.1 CCC69220.1 - 0.18 11.1 0.0 0.29 10.5 0.0 1.2 1 0 0 1 1 1 0 PTRF/SDPR family ODC_AZ PF02100.12 CCC69221.1 - 8.7e-07 28.4 0.0 1.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Arf PF00025.16 CCC69222.1 - 1.1e-48 164.7 0.2 1.4e-48 164.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCC69222.1 - 2.7e-17 62.6 0.0 3.3e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC69222.1 - 2.5e-15 57.0 0.1 3.5e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CCC69222.1 - 6.9e-13 48.2 0.0 8.7e-13 47.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CCC69222.1 - 5.5e-11 42.2 0.1 3.1e-10 39.8 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 CCC69222.1 - 2.4e-09 36.3 0.9 3.3e-06 26.0 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCC69222.1 - 1.4e-07 30.8 0.1 1.8e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 CCC69222.1 - 2.3e-06 27.5 0.1 3.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CCC69222.1 - 0.022 14.9 0.0 0.12 12.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain Anp1 PF03452.9 CCC69223.1 - 6e-109 363.3 0.0 7.3e-109 363.0 0.0 1.1 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 CCC69223.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 EF1G PF00647.14 CCC69224.1 - 1.3e-47 159.8 0.1 2.4e-47 159.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CCC69224.1 - 1.2e-10 41.2 0.1 1.2e-10 41.2 0.0 2.0 3 0 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCC69224.1 - 1.7e-08 34.4 0.0 4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCC69224.1 - 7e-08 32.2 0.1 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCC69224.1 - 1.9e-06 28.2 1.6 2.5e-06 27.8 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCC69224.1 - 0.00051 20.2 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Sgf11 PF08209.6 CCC69225.1 - 1.3e-16 59.5 4.8 1.9e-16 59.0 3.3 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-CpG_bind_C PF12269.3 CCC69225.1 - 0.0006 19.3 0.0 0.00062 19.3 0.0 1.2 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain zf-C2HC_2 PF13913.1 CCC69225.1 - 0.34 10.6 1.6 0.48 10.1 1.1 1.2 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Skp1_POZ PF03931.10 CCC69226.1 - 1.1e-08 35.0 0.1 1.5e-08 34.5 0.1 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Vps16_N PF04841.8 CCC69227.1 - 4.3e-78 262.6 0.1 5.7e-78 262.2 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 CCC69227.1 - 1.6e-74 250.7 5.7 2.4e-74 250.1 3.9 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region RRM_1 PF00076.17 CCC69228.1 - 1.3e-54 181.7 0.8 2.5e-17 62.2 0.1 5.7 5 1 1 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC69228.1 - 8.2e-41 137.8 0.4 3.7e-12 46.0 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC69228.1 - 8.1e-18 64.0 1.5 4.2e-07 29.7 0.0 5.3 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 CCC69228.1 - 0.00039 18.6 11.6 0.00039 18.6 8.1 2.4 2 0 0 2 2 2 1 CDC45-like protein SAPS PF04499.10 CCC69228.1 - 8.9 4.8 18.4 0.19 10.3 3.5 2.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein Pkinase PF00069.20 CCC69229.1 - 1.5e-55 188.1 0.0 3.8e-53 180.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69229.1 - 8.2e-26 90.6 0.1 1.1e-24 86.9 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase FLILHELTA PF10306.4 CCC69230.1 - 1e-21 76.7 0.0 1.6e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA tRNA-synt_1 PF00133.17 CCC69231.1 - 1.2e-166 555.2 0.0 2.1e-166 554.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 CCC69231.1 - 2.7e-24 85.5 4.4 2.5e-12 46.1 0.0 4.2 4 1 0 4 4 4 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 CCC69231.1 - 7.1e-19 68.0 0.4 1.6e-18 66.9 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 CCC69231.1 - 0.0061 16.1 5.9 0.013 15.1 4.1 1.6 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.1 CCC69231.1 - 0.053 12.8 0.0 0.13 11.4 0.0 1.6 1 0 0 1 1 1 0 Leucyl-tRNA synthetase, Domain 2 DZR PF12773.2 CCC69231.1 - 0.26 11.1 2.3 0.44 10.4 1.6 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_4 PF13894.1 CCC69233.1 - 4.4e-08 32.8 9.6 0.00055 20.0 0.2 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCC69233.1 - 1.2e-06 28.5 14.2 0.001 19.3 1.2 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC69233.1 - 0.00014 22.0 5.4 0.018 15.2 0.1 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCC69233.1 - 0.0087 16.1 1.1 0.1 12.7 0.1 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 CCC69233.1 - 0.11 12.4 2.0 1.1 9.2 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Nudix_N_2 PF14803.1 CCC69233.1 - 0.21 11.2 1.1 18 5.1 0.0 2.4 2 0 0 2 2 2 0 Nudix N-terminal C1_4 PF07975.7 CCC69233.1 - 0.23 11.5 0.1 0.23 11.5 0.1 2.2 2 0 0 2 2 2 0 TFIIH C1-like domain XPA_N PF01286.13 CCC69233.1 - 0.48 10.1 3.4 0.71 9.5 0.3 2.4 2 1 0 2 2 2 0 XPA protein N-terminal Ribosomal_L37e PF01907.14 CCC69233.1 - 6.1 6.7 6.9 3.8 7.3 0.6 2.4 1 1 1 2 2 2 0 Ribosomal protein L37e NAC PF01849.13 CCC69234.1 - 1.6e-15 56.3 0.2 3.5e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 NAC domain Glyco_hydro_20b PF02838.10 CCC69234.1 - 0.1 13.1 0.7 0.25 11.8 0.1 1.8 1 1 0 2 2 2 0 Glycosyl hydrolase family 20, domain 2 Aldo_ket_red PF00248.16 CCC69235.1 - 3.4e-58 196.7 0.1 3.9e-58 196.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.7 CCC69235.1 - 0.0023 17.4 0.1 0.021 14.2 0.0 2.0 2 0 0 2 2 2 1 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) PspC PF04024.7 CCC69235.1 - 0.13 11.7 0.1 0.4 10.1 0.0 1.8 2 0 0 2 2 2 0 PspC domain ApbA_C PF08546.6 CCC69236.1 - 7.9e-05 22.6 0.0 0.00018 21.5 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Pkinase PF00069.20 CCC69237.1 - 2.4e-77 259.5 0.0 2.8e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69237.1 - 5.6e-38 130.5 0.0 7.9e-38 130.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC69237.1 - 0.00056 18.9 0.0 0.0014 17.6 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCC69237.1 - 0.039 13.6 0.0 0.52 10.0 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 CCC69237.1 - 0.065 12.0 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DUF1573 PF07610.6 CCC69237.1 - 0.085 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) AdoMet_MTase PF07757.8 CCC69238.1 - 1.3e-41 141.2 0.1 2.1e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.1 CCC69238.1 - 0.0035 16.9 0.1 0.0077 15.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 CCC69238.1 - 0.04 13.5 0.1 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 CCC69238.1 - 0.052 13.2 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SUV3_C PF12513.3 CCC69239.1 - 5.2e-15 54.6 1.7 1.3e-14 53.3 1.2 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 CCC69239.1 - 2.1e-12 46.7 0.0 5.1e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Clathrin-link PF09268.5 CCC69239.1 - 4.8 6.3 6.2 0.72 8.9 1.2 1.9 2 0 0 2 2 2 0 Clathrin, heavy-chain linker Thiolase_N PF00108.18 CCC69240.1 - 1.8e-102 341.8 3.1 2.4e-102 341.4 2.2 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 CCC69240.1 - 1.8e-45 153.3 3.6 3.8e-45 152.2 0.1 2.8 3 1 0 3 3 3 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 CCC69240.1 - 5.6e-06 26.0 0.9 1.2e-05 24.9 0.6 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 CCC69240.1 - 0.059 13.0 0.5 2.9 7.6 0.2 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pkinase PF00069.20 CCC69241.1 - 8.1e-52 175.9 0.5 3.8e-50 170.4 0.4 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69241.1 - 4.5e-23 81.6 0.1 1.5e-19 70.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCC69241.1 - 5.4e-07 28.8 0.0 1.2e-06 27.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCC69241.1 - 0.01 15.5 0.0 0.015 15.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3684 PF12449.3 CCC69242.1 - 0.0024 15.5 0.1 0.0029 15.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) Spo7_2_N PF15407.1 CCC69242.1 - 0.04 13.3 0.0 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 Sporulation protein family 7 MTHFR PF02219.12 CCC69243.1 - 9.5e-111 369.4 0.0 1.2e-110 369.1 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ERCC4 PF02732.10 CCC69244.1 - 4.2e-23 81.6 0.0 1.3e-22 80.1 0.0 1.9 1 0 0 1 1 1 1 ERCC4 domain ARID PF01388.16 CCC69245.1 - 4.4e-20 71.3 1.0 4.4e-20 71.3 0.7 5.7 7 2 0 7 7 7 1 ARID/BRIGHT DNA binding domain RRM_1 PF00076.17 CCC69246.1 - 3.6e-07 29.7 0.0 7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC69246.1 - 0.0024 17.8 0.0 0.0052 16.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC69246.1 - 0.011 15.5 0.1 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GLE1 PF07817.8 CCC69247.1 - 1.4e-88 296.1 0.1 1.4e-88 296.1 0.1 2.3 2 0 0 2 2 2 1 GLE1-like protein Asp-B-Hydro_N PF05279.6 CCC69247.1 - 6.8 6.4 22.3 12 5.6 15.5 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Na_Ca_ex PF01699.19 CCC69248.1 - 2e-52 176.5 23.4 1e-27 96.4 4.9 3.4 2 2 1 3 3 3 2 Sodium/calcium exchanger protein Orbi_NS3 PF01616.11 CCC69248.1 - 6.8 5.5 5.2 20 4.0 0.2 3.2 3 1 0 3 3 3 0 Orbivirus NS3 Porphobil_deam PF01379.15 CCC69249.1 - 5.9e-84 280.2 0.0 7.8e-84 279.8 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 CCC69249.1 - 7.4e-21 74.0 0.4 1.3e-20 73.3 0.3 1.4 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain CEP1-DNA_bind PF09287.5 CCC69249.1 - 0.0088 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 CEP-1, DNA binding Reticulon PF02453.12 CCC69250.1 - 3.6e-19 68.9 0.1 5.1e-19 68.5 0.1 1.1 1 0 0 1 1 1 1 Reticulon DUF4389 PF14333.1 CCC69250.1 - 2.7 7.7 5.4 13 5.5 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Sel1 PF08238.7 CCC69251.1 - 6.5e-28 96.5 9.7 1.6e-05 25.3 0.0 7.9 7 1 0 7 7 7 7 Sel1 repeat TMC PF07810.8 CCC69251.1 - 0.074 13.4 0.1 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 TMC domain Ribosomal_L10 PF00466.15 CCC69252.1 - 1.7e-11 43.8 0.0 2.7e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Methyltransf_4 PF02390.12 CCC69253.1 - 1.5e-61 206.9 0.2 2.3e-61 206.3 0.1 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCC69253.1 - 8.4e-05 23.1 0.0 0.00013 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC69253.1 - 8.4e-05 22.2 0.0 0.00017 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCC69253.1 - 0.0006 19.8 0.0 0.001 19.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCC69253.1 - 0.0015 19.0 0.1 0.0051 17.2 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain DUF2431 PF10354.4 CCC69253.1 - 0.004 17.1 0.2 0.007 16.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) MTS PF05175.9 CCC69253.1 - 0.0057 16.0 0.0 0.024 14.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 CCC69253.1 - 0.046 14.0 0.0 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain FmrO PF07091.6 CCC69253.1 - 0.064 12.2 0.0 0.099 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_11 PF08241.7 CCC69253.1 - 0.095 13.2 0.0 2.6 8.6 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain DUF3958 PF13125.1 CCC69253.1 - 0.12 12.3 2.4 0.16 11.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) DNA_binding_1 PF01035.15 CCC69254.1 - 3.4e-21 74.7 0.0 5e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Lipocalin PF00061.18 CCC69254.1 - 0.17 11.8 1.0 0.28 11.1 0.3 1.6 2 0 0 2 2 2 0 Lipocalin / cytosolic fatty-acid binding protein family Mito_carr PF00153.22 CCC69255.1 - 1.3e-31 108.0 0.2 6.7e-15 54.5 0.0 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein VIT1 PF01988.14 CCC69259.1 - 5.2e-56 189.4 0.5 6.2e-56 189.2 0.3 1.1 1 0 0 1 1 1 1 VIT family Rsa3 PF14615.1 CCC69260.1 - 6.2e-20 70.2 0.2 1e-19 69.5 0.1 1.4 1 0 0 1 1 1 1 Ribosome-assembly protein 3 PLRV_ORF5 PF01690.12 CCC69260.1 - 0.041 13.0 13.7 0.043 12.9 9.5 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF4357 PF14267.1 CCC69260.1 - 0.054 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) NST1 PF13945.1 CCC69260.1 - 1.5 8.8 23.2 0.36 10.8 8.0 2.1 2 0 0 2 2 2 0 Salt tolerance down-regulator SOBP PF15279.1 CCC69260.1 - 3.2 8.0 6.2 4.2 7.6 4.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Macoilin PF09726.4 CCC69260.1 - 7.9 4.6 20.5 9.7 4.3 14.2 1.0 1 0 0 1 1 1 0 Transmembrane protein WD40 PF00400.27 CCC69261.1 - 1.8e-57 189.2 19.3 1.1e-09 37.7 0.0 11.7 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp13 PF08625.6 CCC69261.1 - 1.6e-48 163.9 0.7 3.4e-48 162.8 0.5 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 CCC69261.1 - 5.7e-07 28.0 4.7 2 6.4 0.0 5.2 2 1 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCC69261.1 - 0.061 12.0 4.8 0.7 8.5 0.1 3.9 2 1 1 4 4 4 0 Nup133 N terminal like PIP5K PF01504.13 CCC69262.1 - 6e-79 264.7 4.9 9.3e-79 264.0 3.4 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Fungal_trans_2 PF11951.3 CCC69263.1 - 1.5e-11 43.5 0.2 1.5e-11 43.5 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC69263.1 - 4.7e-10 39.2 10.8 7.2e-10 38.6 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF16 PF01519.11 CCC69263.1 - 0.012 15.8 10.0 0.012 15.8 6.9 2.0 2 0 0 2 2 2 0 Protein of unknown function DUF16 Activator_LAG-3 PF11498.3 CCC69263.1 - 1.4 7.6 33.5 0.88 8.2 0.2 2.4 2 0 0 2 2 2 0 Transcriptional activator LAG-3 DUF2547 PF10818.3 CCC69263.1 - 5.6 7.6 17.3 5.2 7.7 9.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) CRF1 PF10380.4 CCC69266.1 - 1.8e-35 121.9 3.8 1.8e-35 121.9 2.7 4.9 4 1 0 4 4 4 1 Transcription factor CRF1 EST1_DNA_bind PF10373.4 CCC69267.1 - 7.4e-31 107.3 8.0 1.2e-30 106.7 5.5 1.3 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 CCC69267.1 - 1.7e-08 34.4 0.6 1.7e-08 34.4 0.4 2.6 2 0 0 2 2 2 1 Telomerase activating protein Est1 Topoisom_bac PF01131.15 CCC69268.1 - 6.5e-92 308.4 0.0 9.7e-92 307.8 0.0 1.3 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 CCC69268.1 - 2.9e-21 75.3 0.0 8.8e-21 73.7 0.0 1.9 2 0 0 2 2 2 1 Toprim domain Transp_cyt_pur PF02133.10 CCC69269.1 - 2.7e-74 250.3 36.9 3.5e-74 249.9 25.6 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Rogdi_lz PF10259.4 CCC69270.1 - 8.5e-78 261.2 3.6 9.7e-78 261.0 2.5 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein HSP9_HSP12 PF04119.7 CCC69270.1 - 0.087 12.9 1.1 0.18 11.9 0.7 1.5 1 0 0 1 1 1 0 Heat shock protein 9/12 FHA PF00498.21 CCC69271.1 - 1.6e-17 63.3 1.3 1.6e-15 56.9 0.3 3.1 3 0 0 3 3 3 2 FHA domain BPL_LplA_LipB PF03099.14 CCC69272.1 - 1.5e-18 67.0 0.0 2.5e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family YcgR PF07317.7 CCC69272.1 - 0.0019 17.8 0.1 0.0039 16.9 0.0 1.5 1 0 0 1 1 1 1 Flagellar regulator YcgR PI3Ka PF00613.15 CCC69273.1 - 2.3e-73 245.3 1.5 3.4e-73 244.7 1.1 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 CCC69273.1 - 4.8e-47 160.4 0.0 3.6e-46 157.5 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 CCC69273.1 - 2.4e-23 82.4 0.5 7.9e-23 80.8 0.4 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 Kinesin PF00225.18 CCC69273.1 - 0.0012 17.6 0.7 0.0019 16.9 0.5 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF221 PF02714.10 CCC69274.1 - 4.3e-100 334.7 18.2 4.3e-100 334.7 12.6 1.7 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 CCC69274.1 - 1.8e-37 128.3 2.1 1.8e-37 128.3 1.5 2.3 2 1 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 CCC69274.1 - 7.8e-14 51.9 0.0 1.6e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) Arv1 PF04161.8 CCC69275.1 - 8.6e-74 247.9 24.1 1.3e-73 247.3 16.7 1.3 1 0 0 1 1 1 1 Arv1-like family ATP_bind_1 PF03029.12 CCC69276.1 - 2.3e-85 285.9 0.0 2.6e-85 285.7 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CCC69276.1 - 0.00016 21.2 0.0 0.00036 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_17 PF13207.1 CCC69276.1 - 0.00019 22.2 0.1 0.00062 20.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 CCC69276.1 - 0.00062 18.6 0.1 0.0016 17.3 0.0 1.5 2 0 0 2 2 2 1 ArgK protein MMR_HSR1 PF01926.18 CCC69276.1 - 0.0016 18.3 0.0 0.0032 17.3 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCC69276.1 - 0.0066 15.9 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 CCC69276.1 - 0.0084 16.4 0.0 0.015 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter DUF87 PF01935.12 CCC69276.1 - 0.0086 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function DUF87 RNA_helicase PF00910.17 CCC69276.1 - 0.0097 16.0 0.0 0.027 14.6 0.0 1.8 2 0 0 2 2 1 1 RNA helicase T2SE PF00437.15 CCC69276.1 - 0.012 14.5 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 CCC69276.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 CCC69276.1 - 0.016 14.9 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KAP_NTPase PF07693.9 CCC69276.1 - 0.017 14.1 0.0 0.025 13.5 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_24 PF13479.1 CCC69276.1 - 0.019 14.5 0.0 0.045 13.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain FtsK_SpoIIIE PF01580.13 CCC69276.1 - 0.029 13.8 0.1 0.048 13.1 0.1 1.8 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 CCC69276.1 - 0.031 14.1 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCC69276.1 - 0.039 14.1 0.0 0.064 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCC69276.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 CCC69276.1 - 0.051 12.7 0.0 0.095 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA PF00004.24 CCC69276.1 - 0.052 13.7 0.0 0.15 12.3 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 CCC69276.1 - 0.061 13.6 0.1 0.26 11.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCC69276.1 - 0.063 13.0 0.1 0.12 12.1 0.1 1.3 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 CCC69276.1 - 0.072 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 CCC69276.1 - 0.087 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 CCC69276.1 - 0.09 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 CCC69276.1 - 0.12 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin Viral_helicase1 PF01443.13 CCC69276.1 - 0.13 11.7 0.0 0.31 10.5 0.0 1.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 CCC69276.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.9 CCC69276.1 - 0.14 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.14 CCC69276.1 - 0.15 11.5 0.0 1.2 8.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PPV_E1_C PF00519.12 CCC69276.1 - 0.15 10.6 0.0 0.23 10.0 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AIG1 PF04548.11 CCC69276.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.4 1 0 0 1 1 1 0 AIG1 family TIP49 PF06068.8 CCC69277.1 - 2.9e-188 625.5 0.4 3.5e-188 625.3 0.3 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CCC69277.1 - 1.6e-08 34.8 0.1 6.3e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCC69277.1 - 2.6e-08 33.2 1.4 0.00015 20.8 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 CCC69277.1 - 0.0011 18.9 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC69277.1 - 0.0019 18.1 0.0 0.3 11.0 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 CCC69277.1 - 0.006 16.3 0.0 0.02 14.6 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 CCC69277.1 - 0.0099 15.7 0.0 0.77 9.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCC69277.1 - 0.012 14.6 0.1 0.029 13.4 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_5 PF07728.9 CCC69277.1 - 0.023 14.3 0.2 0.9 9.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF4295 PF14128.1 CCC69277.1 - 0.026 14.1 0.5 0.098 12.2 0.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4295) DnaB_C PF03796.10 CCC69277.1 - 0.029 13.2 0.0 0.053 12.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain Mg_chelatase PF01078.16 CCC69277.1 - 0.037 13.1 0.1 4.5 6.3 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCC69277.1 - 0.043 13.2 0.0 5.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain CPT PF07931.7 CCC69277.1 - 0.046 13.3 0.0 0.096 12.2 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sec1 PF00995.18 CCC69278.1 - 5.5e-146 487.4 7.9 6.2e-146 487.3 5.5 1.0 1 0 0 1 1 1 1 Sec1 family PNPase PF03726.9 CCC69278.1 - 0.11 12.7 0.2 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Cpn60_TCP1 PF00118.19 CCC69279.1 - 8.1e-145 483.1 0.9 9.1e-145 482.9 0.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_M24 PF00557.19 CCC69280.1 - 1.1e-47 162.3 0.1 1.5e-47 161.8 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 ATP-cone PF03477.11 CCC69280.1 - 0.042 14.2 0.0 8.9 6.8 0.0 2.3 2 0 0 2 2 2 0 ATP cone domain zf-MYND PF01753.13 CCC69280.1 - 1.9 8.4 12.1 0.047 13.5 2.6 2.5 3 0 0 3 3 3 0 MYND finger dCMP_cyt_deam_1 PF00383.17 CCC69281.1 - 1.1e-16 60.2 0.3 1.4e-16 60.0 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 CCC69281.1 - 1.7e-12 47.4 0.1 2.1e-10 40.6 0.0 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 CCC69281.1 - 0.00045 19.6 0.7 0.4 10.0 0.0 2.1 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases zf-DHHC PF01529.15 CCC69282.1 - 4.1e-36 123.9 8.7 4.1e-36 123.9 6.1 2.0 1 1 1 2 2 2 1 DHHC palmitoyltransferase PRELI PF04707.9 CCC69283.1 - 5.4e-54 182.0 0.0 1e-53 181.0 0.0 1.5 1 1 0 1 1 1 1 PRELI-like family COG2 PF06148.6 CCC69283.1 - 0.0096 15.7 0.1 0.015 15.1 0.0 1.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 ubiquitin PF00240.18 CCC69284.1 - 1.4e-34 117.2 0.9 2.7e-34 116.3 0.6 1.5 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 CCC69284.1 - 7.3e-26 89.7 4.2 1.3e-25 88.9 2.9 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 CCC69284.1 - 1e-19 69.9 0.7 1e-19 69.9 0.5 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCC69284.1 - 8.5e-06 25.9 0.2 3.9e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCC69284.1 - 0.00012 21.8 0.0 0.00017 21.3 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCC69284.1 - 0.0012 18.7 0.4 0.0025 17.6 0.3 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCC69284.1 - 0.0045 17.1 0.4 0.0058 16.7 0.3 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain IBR PF01485.16 CCC69284.1 - 0.06 13.2 0.3 0.091 12.6 0.2 1.3 1 0 0 1 1 1 0 IBR domain DUF2870 PF11069.3 CCC69284.1 - 0.068 13.2 0.1 0.14 12.2 0.0 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 CCC69284.1 - 0.16 10.2 2.1 5 5.3 0.1 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain Sec10 PF07393.6 CCC69285.1 - 7.6e-195 649.1 24.3 7.6e-195 649.1 16.8 1.3 2 0 0 2 2 2 1 Exocyst complex component Sec10 Occludin_ELL PF07303.8 CCC69285.1 - 0.27 11.9 7.0 0.28 11.9 0.9 3.0 1 1 1 2 2 2 0 Occludin homology domain PseudoU_synth_2 PF00849.17 CCC69286.1 - 6.7e-19 68.3 0.0 1.8e-18 66.9 0.0 1.7 1 1 0 1 1 1 1 RNA pseudouridylate synthase OmdA PF13376.1 CCC69286.1 - 0.13 11.9 0.0 1.1 8.9 0.0 2.3 3 0 0 3 3 3 0 Bacteriocin-protection, YdeI or OmpD-Associated Peptidase_M16 PF00675.15 CCC69287.1 - 9.3e-53 177.9 0.0 2.3e-52 176.7 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCC69287.1 - 3.4e-38 131.1 0.0 1.6e-37 128.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain BHD_1 PF10403.4 CCC69288.1 - 3.9e-10 39.0 0.0 8.9e-10 37.9 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 Rad4 PF03835.10 CCC69288.1 - 2.3e-09 36.8 0.9 8.4e-09 34.9 0.2 2.3 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_2 PF10404.4 CCC69288.1 - 4.1e-08 33.4 1.0 1.8e-07 31.3 0.7 2.2 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 2 BHD_3 PF10405.4 CCC69288.1 - 2.4e-05 23.9 0.2 4.8e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Sugar_tr PF00083.19 CCC69289.1 - 4.1e-168 559.6 32.6 4.8e-168 559.4 22.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC69289.1 - 2.1e-27 95.7 26.6 4e-25 88.2 11.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCC69289.1 - 0.0082 14.3 3.0 0.019 13.0 0.8 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector GST_N PF02798.15 CCC69290.1 - 9.8e-10 38.4 0.0 1.8e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 CCC69290.1 - 2.4e-09 37.0 0.0 4.7e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCC69290.1 - 3.3e-06 27.2 0.0 6.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCC69290.1 - 4.8e-05 23.1 0.0 8.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 CCC69290.1 - 0.00053 20.4 0.0 0.0011 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 CCC69290.1 - 0.0019 18.1 0.0 0.0033 17.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF21 PF01595.15 CCC69291.1 - 1.4e-32 112.5 0.2 2.2e-32 111.8 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 CCC69291.1 - 1e-05 25.1 0.0 0.027 14.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain ADH_N PF08240.7 CCC69292.1 - 2.3e-26 91.6 2.9 4e-26 90.9 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCC69292.1 - 1.5e-17 63.4 0.0 2.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCC69292.1 - 3.5e-06 26.2 0.2 1.3e-05 24.4 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CCC69292.1 - 0.034 13.7 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 CCC69292.1 - 0.049 13.4 0.0 0.075 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 CCC69292.1 - 0.083 13.1 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DUP PF00674.13 CCC69293.1 - 9.1e-15 54.5 1.0 2.1e-13 50.1 0.1 2.2 2 0 0 2 2 2 1 DUP family DUF4634 PF15465.1 CCC69293.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) AgrB PF04647.10 CCC69293.1 - 0.047 12.7 3.2 0.094 11.7 0.2 2.0 2 0 0 2 2 2 0 Accessory gene regulator B AMP-binding PF00501.23 CCC69294.1 - 2.5e-89 299.5 0.0 3.2e-89 299.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCC69294.1 - 2.5e-16 60.3 0.0 7.3e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain NUDIX PF00293.23 CCC69295.1 - 1.6e-16 60.1 0.1 6.1e-16 58.2 0.0 1.9 1 1 0 1 1 1 1 NUDIX domain Stb3 PF10330.4 CCC69296.1 - 1.1e-30 105.1 0.0 2e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Putative Sin3 binding protein DUF2415 PF10313.4 CCC69297.1 - 1.3e-20 72.7 0.8 4.9e-20 70.9 0.4 2.1 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) Str_synth PF03088.11 CCC69297.1 - 0.01 15.8 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 Strictosidine synthase Pep3_Vps18 PF05131.9 CCC69298.1 - 7.6e-37 125.9 0.8 7.6e-37 125.9 0.5 2.5 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 CCC69298.1 - 3.5e-08 33.1 5.5 3.5e-08 33.1 3.8 3.0 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.4 CCC69298.1 - 2.9e-05 24.1 1.3 2.9e-05 24.1 0.9 2.6 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 zf-RING_2 PF13639.1 CCC69298.1 - 0.00032 20.4 5.7 0.00032 20.4 4.0 2.3 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 CCC69298.1 - 0.15 11.8 12.3 0.5 10.1 8.6 2.0 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCC69298.1 - 3.3 7.8 12.5 0.034 14.1 2.5 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LSM PF01423.17 CCC69299.1 - 3.1e-15 55.4 1.0 3.7e-15 55.2 0.7 1.1 1 0 0 1 1 1 1 LSM domain PAP1 PF08601.5 CCC69300.1 - 0.0077 15.9 0.1 0.0083 15.8 0.1 1.1 1 0 0 1 1 1 1 Transcription factor PAP1 EF-hand_4 PF12763.2 CCC69300.1 - 0.011 15.4 0.1 0.012 15.2 0.1 1.0 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand Orthopox_F14 PF06076.7 CCC69300.1 - 0.028 14.4 0.1 0.032 14.2 0.1 1.2 1 0 0 1 1 1 0 Orthopoxvirus F14 protein Spermine_synth PF01564.12 CCC69301.1 - 6.2e-87 290.5 0.9 9e-87 290.0 0.6 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 CCC69301.1 - 0.00043 20.8 0.0 0.00076 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC69301.1 - 0.00077 19.2 0.0 0.0022 17.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCC69301.1 - 0.0013 18.7 0.0 0.0025 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 CCC69301.1 - 0.0046 15.9 0.0 0.0068 15.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_3 PF01596.12 CCC69301.1 - 0.0086 15.1 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 CCC69301.1 - 0.11 12.9 0.1 0.32 11.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DUF4477 PF14780.1 CCC69302.1 - 0.025 13.9 6.1 0.12 11.6 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4477) Glyco_hydro_81 PF03639.8 CCC69303.1 - 9.9e-227 754.2 12.9 1.3e-226 753.9 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Pro_dh PF01619.13 CCC69306.1 - 5.1e-62 209.6 0.0 6.7e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase GTP-bdg_N PF13167.1 CCC69306.1 - 0.0059 16.7 0.0 0.023 14.8 0.0 2.0 2 0 0 2 2 2 1 GTP-binding GTPase N-terminal SLS PF14611.1 CCC69308.1 - 1.3e-16 60.6 10.9 5.1e-16 58.7 5.7 3.1 2 1 0 2 2 2 1 Mitochondrial inner-membrane-bound regulator SR-25 PF10500.4 CCC69308.1 - 0.056 12.9 12.0 0.11 11.9 8.4 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WRKY PF03106.10 CCC69308.1 - 0.61 9.9 2.8 0.45 10.4 0.1 2.1 2 0 0 2 2 2 0 WRKY DNA -binding domain Na_H_Exchanger PF00999.16 CCC69309.1 - 3e-78 262.9 28.0 3.6e-78 262.7 19.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Nha1_C PF08619.5 CCC69309.1 - 8.5e-77 259.2 44.8 8.5e-77 259.2 31.1 1.6 1 1 1 2 2 2 1 Alkali metal cation/H+ antiporter Nha1 C terminus Methyltransf_16 PF10294.4 CCC69310.1 - 2.6e-09 36.7 1.9 4.5e-06 26.2 1.3 2.1 1 1 0 1 1 1 1 Putative methyltransferase 2OG-FeII_Oxy PF03171.15 CCC69310.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Slx4 PF09494.5 CCC69311.1 - 1.6e-13 50.1 0.1 3.6e-13 49.0 0.1 1.6 1 0 0 1 1 1 1 Slx4 endonuclease DUF4066 PF13278.1 CCC69311.1 - 0.063 12.5 0.0 0.15 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative amidotransferase Choline_kinase PF01633.15 CCC69312.1 - 5.4e-65 218.9 0.0 8.3e-65 218.3 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 CCC69312.1 - 3.3e-14 52.0 1.2 5.3e-14 51.4 0.1 1.9 2 0 0 2 2 2 1 Choline kinase N terminus APH PF01636.18 CCC69312.1 - 1.3e-07 31.6 0.0 0.015 15.0 0.0 2.5 2 1 0 2 2 2 2 Phosphotransferase enzyme family Corona_nucleoca PF00937.13 CCC69312.1 - 0.33 9.8 1.7 0.59 9.0 1.2 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein HVSL PF09749.4 CCC69313.1 - 2.5e-27 95.4 0.1 3.1e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.1 CCC69313.1 - 0.00055 19.6 0.4 0.0011 18.6 0.3 1.5 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily Tautomerase_2 PF14552.1 CCC69313.1 - 0.039 13.9 0.0 0.27 11.2 0.0 2.2 2 0 0 2 2 2 0 Tautomerase enzyme zf-C2H2 PF00096.21 CCC69314.1 - 4.4e-09 36.1 6.9 0.00013 22.0 0.5 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC69314.1 - 1.8e-05 24.7 5.0 0.03 14.6 0.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCC69314.1 - 0.00018 21.5 6.9 0.0007 19.7 0.1 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-TRAF PF02176.13 CCC69314.1 - 0.012 16.0 0.5 0.022 15.1 0.4 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger Acyl_transf_2 PF02273.10 CCC69314.1 - 0.086 11.8 0.7 0.13 11.2 0.5 1.2 1 0 0 1 1 1 0 Acyl transferase zf-C2H2_jaz PF12171.3 CCC69314.1 - 0.38 10.9 3.4 11 6.3 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding AAA_23 PF13476.1 CCC69314.1 - 0.48 10.7 12.4 5.3 7.3 6.3 2.3 2 0 0 2 2 2 0 AAA domain Zip PF02535.17 CCC69315.1 - 1.3e-65 221.4 2.3 5.9e-65 219.3 1.6 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3295 PF11702.3 CCC69315.1 - 1.2 8.0 8.9 1.5 7.6 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) WD40 PF00400.27 CCC69316.1 - 2.5e-68 223.6 33.1 7.7e-09 35.1 0.1 11.9 13 0 0 13 13 13 10 WD domain, G-beta repeat Utp12 PF04003.7 CCC69316.1 - 3.2e-23 81.7 0.5 5.8e-23 80.8 0.4 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 CCC69316.1 - 3.4e-06 25.4 6.9 0.0052 14.9 0.0 4.9 3 2 1 4 4 4 3 Nucleoporin Nup120/160 SynMuv_product PF06047.6 CCC69316.1 - 0.044 13.5 1.1 0.16 11.7 0.2 2.3 2 0 0 2 2 2 0 Ras-induced vulval development antagonist Cullin_binding PF03556.10 CCC69317.1 - 1.2e-29 102.8 5.3 1.6e-29 102.3 3.7 1.2 1 0 0 1 1 1 1 Cullin binding Cullin PF00888.17 CCC69318.1 - 1.1e-27 96.8 10.5 1.1e-27 96.8 7.3 1.9 2 0 0 2 2 2 1 Cullin family APC2 PF08672.6 CCC69318.1 - 2.8e-17 62.7 5.3 6e-16 58.4 0.1 4.3 4 0 0 4 4 4 1 Anaphase promoting complex (APC) subunit 2 FeoC PF09012.5 CCC69318.1 - 0.00086 18.9 0.1 0.0052 16.4 0.0 2.2 2 0 0 2 2 2 1 FeoC like transcriptional regulator DUF746 PF05344.6 CCC69318.1 - 0.037 13.5 0.0 16 5.0 0.0 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF746) GATase PF00117.23 CCC69319.1 - 2.6e-12 46.5 0.0 3.5e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCC69319.1 - 0.0031 16.9 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 STb_secrete PF09075.5 CCC69319.1 - 0.15 11.9 0.7 0.3 10.9 0.5 1.5 1 0 0 1 1 1 0 Heat-stable enterotoxin B, secretory Asp PF00026.18 CCC69320.1 - 1.6e-75 254.3 13.6 1.6e-75 254.3 9.4 1.9 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCC69320.1 - 6.8e-08 32.6 0.9 6.8e-08 32.6 0.6 3.3 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 CCC69320.1 - 0.00064 19.2 1.5 0.043 13.3 0.5 3.5 3 1 0 3 3 3 1 Xylanase inhibitor C-terminal Siva PF05458.7 CCC69320.1 - 0.023 14.2 0.7 0.036 13.6 0.5 1.2 1 0 0 1 1 1 0 Cd27 binding protein (Siva) Asp_protease_2 PF13650.1 CCC69320.1 - 1.4 9.4 11.8 37 4.9 0.2 4.6 4 1 0 4 4 4 0 Aspartyl protease Plasmodium_Vir PF05795.6 CCC69320.1 - 1.4 7.9 7.6 2.4 7.2 5.3 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein TMEM154 PF15102.1 CCC69320.1 - 7.9 6.1 9.7 0.58 9.8 2.4 2.1 1 1 1 2 2 2 0 TMEM154 protein family zf-RING_2 PF13639.1 CCC69321.1 - 1.2e-10 41.0 8.6 8.3e-10 38.3 3.4 2.3 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 CCC69321.1 - 6.3e-06 26.2 5.4 5.6e-05 23.1 3.7 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CCC69321.1 - 5.3e-05 22.8 0.9 5.3e-05 22.8 0.6 2.7 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CCC69321.1 - 5.4e-05 23.1 8.8 5.9e-05 23.0 3.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCC69321.1 - 5.8e-05 22.6 5.4 8.1e-05 22.2 1.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC69321.1 - 0.00017 21.2 6.4 0.0028 17.3 2.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 CCC69321.1 - 0.0006 19.6 3.8 0.0006 19.6 2.7 1.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 CCC69321.1 - 0.0017 17.9 7.9 0.0031 17.1 2.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF912 PF06024.7 CCC69321.1 - 0.043 13.8 0.5 0.043 13.8 0.3 3.7 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) zf-Apc11 PF12861.2 CCC69321.1 - 0.052 13.3 1.0 0.14 11.9 0.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Mod_r PF07200.8 CCC69322.1 - 1.7e-23 83.2 18.1 2e-23 82.9 12.6 1.0 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein DUF2959 PF11172.3 CCC69322.1 - 0.0067 16.1 5.6 0.0085 15.8 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2959) AKNA PF12443.3 CCC69322.1 - 0.009 16.0 2.0 0.009 16.0 1.4 2.4 1 1 1 2 2 2 1 AT-hook-containing transcription factor CENP-F_leu_zip PF10473.4 CCC69322.1 - 0.011 15.6 15.5 0.066 13.0 4.7 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF724 PF05266.9 CCC69322.1 - 0.011 15.3 5.2 0.011 15.3 3.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DASH_Spc34 PF08657.5 CCC69322.1 - 0.016 14.9 10.8 0.018 14.7 7.2 1.3 1 1 0 1 1 1 0 DASH complex subunit Spc34 TBPIP PF07106.8 CCC69322.1 - 0.018 14.5 5.5 0.018 14.5 3.8 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 CCC69322.1 - 0.02 14.7 3.6 0.02 14.7 2.5 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG6 PF04111.7 CCC69322.1 - 0.023 13.7 13.8 0.032 13.3 9.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 CCC69322.1 - 0.065 12.8 20.9 0.066 12.8 13.7 1.5 1 1 0 1 1 1 0 IncA protein 4HB_MCP_1 PF12729.2 CCC69322.1 - 0.069 12.4 7.2 0.076 12.3 4.5 1.4 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction DUF904 PF06005.7 CCC69322.1 - 0.074 13.3 16.3 0.23 11.7 10.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Seryl_tRNA_N PF02403.17 CCC69322.1 - 0.097 12.6 10.0 0.2 11.6 5.4 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.7 CCC69322.1 - 0.11 12.8 4.0 0.4 10.9 0.2 2.4 1 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein AbiH PF14253.1 CCC69322.1 - 0.14 11.7 5.8 0.17 11.4 4.0 1.1 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH GAS PF13851.1 CCC69322.1 - 0.15 11.2 15.3 0.27 10.4 10.5 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding PilJ PF13675.1 CCC69322.1 - 0.15 12.3 4.1 1.2 9.4 0.7 2.2 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DivIC PF04977.10 CCC69322.1 - 0.25 10.8 11.7 0.4 10.2 4.9 2.9 1 1 1 2 2 2 0 Septum formation initiator PCRF PF03462.13 CCC69322.1 - 0.26 10.9 5.7 2.2 8.0 0.2 2.4 2 0 0 2 2 2 0 PCRF domain Prefoldin PF02996.12 CCC69322.1 - 0.26 10.9 9.5 0.24 11.0 1.4 2.9 1 1 2 3 3 3 0 Prefoldin subunit DUF4140 PF13600.1 CCC69322.1 - 0.27 11.7 5.0 0.21 12.0 1.3 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 CCC69322.1 - 0.3 10.7 13.1 0.69 9.5 8.4 1.9 1 1 0 1 1 1 0 Mnd1 family Spc24 PF08286.6 CCC69322.1 - 0.37 10.4 12.9 0.35 10.5 4.1 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Occludin_ELL PF07303.8 CCC69322.1 - 0.38 11.5 12.9 0.95 10.2 4.0 2.2 1 1 1 2 2 2 0 Occludin homology domain Ax_dynein_light PF10211.4 CCC69322.1 - 0.46 10.2 14.9 0.57 9.9 4.5 2.2 1 1 1 2 2 2 0 Axonemal dynein light chain V_ATPase_I PF01496.14 CCC69322.1 - 0.47 8.2 10.2 1 7.1 7.1 1.5 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.6 CCC69322.1 - 0.76 9.6 8.9 8.4 6.2 5.1 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3373 PF11853.3 CCC69322.1 - 0.83 8.1 3.6 1 7.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Vps51 PF08700.6 CCC69322.1 - 1.2 8.9 6.8 4.2 7.2 0.1 3.6 1 1 1 3 3 3 0 Vps51/Vps67 FlxA PF14282.1 CCC69322.1 - 1.3 8.9 13.5 24 4.9 9.3 2.2 1 1 0 1 1 1 0 FlxA-like protein DUF972 PF06156.8 CCC69322.1 - 1.4 9.2 13.2 10 6.5 9.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Lge1 PF11488.3 CCC69322.1 - 1.7 8.9 13.2 1.9 8.7 0.4 2.8 3 1 0 3 3 2 0 Transcriptional regulatory protein LGE1 Retrotrans_gag PF03732.12 CCC69322.1 - 2.1 8.4 7.7 1.7 8.7 0.3 2.9 1 1 2 3 3 3 0 Retrotransposon gag protein Nup54 PF13874.1 CCC69322.1 - 2.2 7.9 9.4 4.1 7.0 6.5 1.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Viral_P18 PF04521.8 CCC69322.1 - 2.3 7.6 10.0 0.3 10.5 2.4 2.3 2 1 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein Tropomyosin_1 PF12718.2 CCC69322.1 - 2.4 7.9 18.1 21 4.9 12.6 2.1 1 1 0 1 1 1 0 Tropomyosin like YlqD PF11068.3 CCC69322.1 - 2.4 8.1 16.2 0.27 11.2 1.5 2.3 1 1 1 2 2 2 0 YlqD protein bZIP_1 PF00170.16 CCC69322.1 - 2.4 8.1 10.1 0.91 9.5 3.1 3.0 2 1 0 2 2 2 0 bZIP transcription factor Syntaxin PF00804.20 CCC69322.1 - 2.7 8.2 10.9 11 6.2 7.5 2.0 1 1 0 1 1 1 0 Syntaxin H-kinase_dim PF02895.9 CCC69322.1 - 2.9 8.2 7.1 1.5 9.1 1.3 2.3 1 1 1 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Laminin_II PF06009.7 CCC69322.1 - 3.2 7.4 7.5 2.8 7.6 0.5 2.2 1 1 1 2 2 2 0 Laminin Domain II DUF2968 PF11180.3 CCC69322.1 - 3.4 7.0 10.8 0.7 9.2 2.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Med4 PF10018.4 CCC69322.1 - 4.6 6.6 11.0 2.1 7.7 5.4 1.8 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF641 PF04859.7 CCC69322.1 - 4.9 6.9 8.8 1.2 8.8 2.2 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) UPF0449 PF15136.1 CCC69322.1 - 5.4 7.3 7.9 0.47 10.6 1.1 2.3 2 1 0 2 2 2 0 Uncharacterised protein family UPF0449 OmpH PF03938.9 CCC69322.1 - 5.8 6.8 10.6 11 5.8 7.4 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin-6_N PF09177.6 CCC69322.1 - 5.9 7.3 10.1 11 6.4 1.1 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF3166 PF11365.3 CCC69322.1 - 7.7 7.0 8.5 3.2 8.2 4.1 1.8 2 1 0 2 2 1 0 Protein of unknown function (DUF3166) ACCA PF03255.9 CCC69322.1 - 8.2 5.9 7.3 2.6 7.5 2.1 1.9 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit P4Ha_N PF08336.6 CCC69322.1 - 8.6 6.1 10.5 4.6 7.0 4.3 2.5 1 1 1 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region DUF342 PF03961.8 CCC69322.1 - 8.7 4.6 11.0 13 4.0 6.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF342) CENP-Q PF13094.1 CCC69322.1 - 9.4 6.2 16.8 47 3.9 11.4 2.3 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Abhydrolase_2 PF02230.11 CCC69323.1 - 8.3e-52 175.7 0.0 9.2e-52 175.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.8 CCC69323.1 - 1.1e-09 38.1 0.0 7e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 CCC69323.1 - 8.8e-09 35.2 0.0 1.4e-08 34.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCC69323.1 - 0.00043 20.2 0.0 0.00098 19.0 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 CCC69323.1 - 0.00044 19.5 0.8 0.36 10.0 0.0 2.8 2 1 1 3 3 3 2 Prolyl oligopeptidase family Cutinase PF01083.17 CCC69323.1 - 0.019 14.7 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Cutinase tRNA-synt_1e PF01406.14 CCC69323.1 - 0.12 11.5 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain TPR_14 PF13428.1 CCC69324.1 - 1.2e-18 65.8 0.0 0.0011 19.4 0.0 9.3 6 2 4 10 10 10 3 Tetratricopeptide repeat HAT PF02184.11 CCC69324.1 - 6.1e-13 48.2 34.7 3.3e-05 23.5 0.4 9.6 10 0 0 10 10 10 4 HAT (Half-A-TPR) repeat TPR_16 PF13432.1 CCC69324.1 - 3.6e-09 37.0 0.5 0.058 14.0 0.0 6.9 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCC69324.1 - 2.2e-08 34.3 0.1 0.16 12.3 0.0 5.6 6 1 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCC69324.1 - 5.3e-05 23.0 3.0 0.0026 17.8 0.1 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 CCC69324.1 - 7.6e-05 22.4 20.7 0.011 15.4 0.6 6.5 5 2 2 7 7 7 3 U3 small nucleolar RNA-associated protein 6 TPR_2 PF07719.12 CCC69324.1 - 0.0093 15.8 7.6 43 4.3 0.0 6.7 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_11 PF13414.1 CCC69324.1 - 0.049 13.2 6.8 3.3 7.4 0.0 4.8 5 0 0 5 5 5 0 TPR repeat TPR_6 PF13174.1 CCC69324.1 - 0.23 12.0 7.4 18 6.0 0.0 6.2 8 0 0 8 8 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCC69324.1 - 0.24 11.2 2.6 19 5.2 0.0 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat G10 PF01125.12 CCC69324.1 - 0.31 10.5 2.9 4.7 6.7 0.2 3.2 3 0 0 3 3 3 0 G10 protein TPR_8 PF13181.1 CCC69324.1 - 0.76 9.7 8.4 25 4.9 0.1 5.6 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCC69324.1 - 1.4 8.9 8.5 21 5.1 0.0 5.2 6 0 0 6 6 5 0 Tetratricopeptide repeat KH_1 PF00013.24 CCC69325.1 - 2.5e-06 27.0 0.1 4.9e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CCC69325.1 - 6.6e-06 25.6 0.0 1.5e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.18 CCC69325.1 - 8.9e-06 25.3 8.9 0.00018 21.2 0.5 2.3 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 CCC69325.1 - 0.014 15.1 9.2 0.1 12.3 2.0 2.4 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 CCC69325.1 - 0.018 14.6 6.5 1 9.0 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_6 PF15288.1 CCC69325.1 - 0.73 9.5 7.8 1.7 8.3 1.3 2.8 1 1 1 2 2 2 0 Zinc knuckle eIF3g PF12353.3 CCC69325.1 - 1.9 8.3 7.5 5.1 7.0 1.8 2.5 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G Prim_Zn_Ribbon PF08273.7 CCC69325.1 - 3 7.9 6.4 1.1 9.4 2.4 1.7 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase CPSF100_C PF13299.1 CCC69326.1 - 5.4e-28 98.1 0.3 5.4e-28 98.1 0.2 3.6 3 1 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 CCC69326.1 - 2.1e-08 34.1 0.1 8.4e-08 32.2 0.0 2.1 2 0 0 2 2 2 1 Beta-Casp domain Avl9 PF09794.4 CCC69327.1 - 7.4e-149 495.3 0.2 1.2e-148 494.6 0.1 1.4 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 CCC69327.1 - 2e-09 37.1 0.6 7.4e-07 28.8 0.2 2.9 2 1 0 2 2 2 1 Stabilization of polarity axis DENN PF02141.16 CCC69327.1 - 0.0091 15.7 1.6 0.2 11.3 0.5 2.9 2 1 0 2 2 2 1 DENN (AEX-3) domain DUF4288 PF14119.1 CCC69327.1 - 0.069 13.2 2.0 0.15 12.1 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4288) Pkinase PF00069.20 CCC69328.1 - 1.3e-69 234.2 0.0 1.8e-69 233.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69328.1 - 1.9e-30 105.7 0.0 2.8e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCC69328.1 - 3e-05 23.1 0.1 0.0001 21.4 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC69328.1 - 0.00047 19.9 0.7 0.0046 16.7 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 CCC69328.1 - 0.0033 16.4 0.0 0.1 11.5 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Flocculin_t3 PF13928.1 CCC69329.1 - 6.5e-14 51.8 17.7 6.5e-14 51.8 12.3 3.2 3 0 0 3 3 3 1 Flocculin type 3 repeat zf-piccolo PF05715.8 CCC69329.1 - 4.1 7.4 7.0 5.1 7.1 0.3 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger Redoxin PF08534.5 CCC69330.1 - 1.1e-27 96.3 0.3 1.3e-27 96.1 0.2 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 CCC69330.1 - 1.4e-08 34.4 0.1 2e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family DUF1462 PF07315.6 CCC69330.1 - 0.0092 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1462) BTB_2 PF02214.17 CCC69331.1 - 1.8e-08 34.4 2.3 0.00057 20.0 0.2 3.0 2 1 0 2 2 2 2 BTB/POZ domain RNase_T PF00929.19 CCC69332.1 - 8.6e-22 78.1 0.8 6.9e-20 71.9 0.2 2.4 2 0 0 2 2 2 2 Exonuclease CHORD PF04968.7 CCC69332.1 - 0.0036 17.5 4.0 0.0094 16.1 2.8 1.7 1 0 0 1 1 1 1 CHORD DNA_pol_A_exo1 PF01612.15 CCC69332.1 - 0.0075 15.7 0.8 0.033 13.6 0.1 2.4 2 1 0 2 2 2 1 3'-5' exonuclease AAA_5 PF07728.9 CCC69333.1 - 1.9e-126 416.4 1.5 6.9e-21 74.4 0.0 9.7 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCC69333.1 - 4.9e-32 110.2 0.0 1.7e-10 40.6 0.0 7.9 8 0 0 8 8 8 4 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 CCC69333.1 - 1.6e-25 89.8 3.7 6.5e-05 23.1 0.1 7.8 7 0 0 7 7 7 4 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCC69333.1 - 1.5e-18 66.8 0.1 0.0076 15.7 0.0 6.5 6 0 0 6 6 5 5 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 CCC69333.1 - 9.1e-18 64.6 0.3 0.0035 17.4 0.0 7.2 7 0 0 7 7 7 3 Sigma-54 interaction domain AAA_16 PF13191.1 CCC69333.1 - 2.9e-16 60.0 5.7 0.0078 16.2 0.0 7.6 7 1 0 7 7 6 4 AAA ATPase domain T2SE PF00437.15 CCC69333.1 - 3.1e-16 59.0 2.2 0.0091 14.9 0.2 6.4 6 0 0 6 6 6 5 Type II/IV secretion system protein AAA_22 PF13401.1 CCC69333.1 - 8.6e-15 55.0 4.1 0.038 14.1 0.0 8.3 8 0 0 8 8 7 3 AAA domain UPF0079 PF02367.12 CCC69333.1 - 1.4e-12 47.2 5.9 0.031 13.8 0.0 6.3 6 0 0 6 6 6 3 Uncharacterised P-loop hydrolase UPF0079 AAA_33 PF13671.1 CCC69333.1 - 1.1e-11 44.8 1.5 0.24 11.2 0.3 6.7 6 2 0 6 6 6 2 AAA domain AAA_17 PF13207.1 CCC69333.1 - 2.8e-11 44.2 32.6 0.05 14.4 0.0 9.3 8 1 0 9 9 6 5 AAA domain PduV-EutP PF10662.4 CCC69333.1 - 1.7e-10 40.5 2.9 0.073 12.5 0.0 6.2 6 0 0 6 6 6 2 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 CCC69333.1 - 5.1e-10 39.7 29.5 0.0054 17.0 0.0 8.6 8 1 0 8 8 7 3 ABC transporter DUF258 PF03193.11 CCC69333.1 - 5.8e-10 38.5 8.1 0.098 11.8 0.7 5.8 6 0 0 6 6 6 3 Protein of unknown function, DUF258 Miro PF08477.8 CCC69333.1 - 1.2e-09 38.7 7.8 0.092 13.2 0.1 7.5 7 0 0 7 7 6 2 Miro-like protein AAA_19 PF13245.1 CCC69333.1 - 1.6e-09 37.3 5.0 1.2 8.9 0.1 6.2 6 0 0 6 6 6 3 Part of AAA domain RNA_helicase PF00910.17 CCC69333.1 - 2.8e-09 37.0 8.6 0.54 10.4 0.0 7.9 8 0 0 8 8 6 2 RNA helicase Mg_chelatase PF01078.16 CCC69333.1 - 5.2e-09 35.5 1.9 3.6 6.6 0.0 8.8 9 1 1 10 10 10 1 Magnesium chelatase, subunit ChlI AAA_29 PF13555.1 CCC69333.1 - 3.8e-08 32.7 1.3 0.59 9.7 0.0 6.2 6 0 0 6 6 6 1 P-loop containing region of AAA domain MobB PF03205.9 CCC69333.1 - 8.8e-08 31.9 8.8 0.34 10.5 0.1 6.7 6 0 0 6 6 6 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 CCC69333.1 - 9.8e-08 31.6 3.7 0.21 10.9 0.0 5.7 6 0 0 6 6 4 2 AAA domain MMR_HSR1 PF01926.18 CCC69333.1 - 1.7e-07 31.2 2.8 4.1 7.3 0.0 6.9 6 0 0 6 6 6 1 50S ribosome-binding GTPase IstB_IS21 PF01695.12 CCC69333.1 - 3.2e-07 29.9 0.1 1.1 8.6 0.0 5.8 6 0 0 6 6 6 1 IstB-like ATP binding protein NACHT PF05729.7 CCC69333.1 - 3.6e-07 29.9 5.2 0.95 9.0 0.1 5.6 5 0 0 5 5 5 1 NACHT domain RuvB_N PF05496.7 CCC69333.1 - 8.8e-07 28.2 1.2 2.2 7.2 0.1 5.8 6 0 0 6 6 6 1 Holliday junction DNA helicase ruvB N-terminus AAA_7 PF12775.2 CCC69333.1 - 2.7e-06 26.6 1.8 2.1 7.3 0.0 4.5 5 0 0 5 5 5 3 P-loop containing dynein motor region D3 PhoH PF02562.11 CCC69333.1 - 8.6e-06 25.1 1.0 3.9 6.6 0.0 4.9 5 0 0 5 5 5 1 PhoH-like protein AAA_28 PF13521.1 CCC69333.1 - 1.8e-05 24.7 9.2 2.5 8.0 0.1 6.0 5 0 0 5 5 5 1 AAA domain ATP-synt_ab PF00006.20 CCC69333.1 - 6.5e-05 22.5 1.5 1.6 8.2 0.0 4.1 5 0 0 5 5 3 2 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.17 CCC69333.1 - 0.00017 21.0 9.9 0.54 9.6 0.4 5.3 6 0 0 6 6 5 1 SRP54-type protein, GTPase domain AAA_18 PF13238.1 CCC69333.1 - 0.0012 19.2 47.2 0.032 14.5 0.0 10.6 8 2 0 9 9 6 3 AAA domain FtsK_SpoIIIE PF01580.13 CCC69333.1 - 8.2 5.8 11.1 11 5.4 0.0 4.9 6 0 0 6 6 4 0 FtsK/SpoIIIE family tRNA_int_endo PF01974.12 CCC69334.1 - 1.4e-23 82.4 0.2 3e-23 81.4 0.1 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 CCC69334.1 - 0.029 13.9 0.3 0.21 11.1 0.0 2.4 3 0 0 3 3 3 0 tRNA intron endonuclease, N-terminal domain DUF2208 PF09973.4 CCC69334.1 - 0.034 13.3 0.1 0.058 12.6 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) DUF743 PF05332.6 CCC69335.1 - 0.032 14.1 0.1 0.076 12.9 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF743) MFS_1 PF07690.11 CCC69336.1 - 1.1e-36 126.3 51.9 4.4e-34 117.7 23.1 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCC69336.1 - 3.3e-11 42.4 13.2 3.3e-11 42.4 9.2 3.5 4 0 0 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 CCC69336.1 - 4.8e-11 41.5 8.2 4.8e-11 41.5 5.7 3.1 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Nuf2 PF03800.9 CCC69338.1 - 4.3e-43 146.8 1.4 4.3e-43 146.8 1.0 3.0 2 1 1 3 3 3 1 Nuf2 family MscS_porin PF12795.2 CCC69338.1 - 0.023 14.0 38.5 0.64 9.2 25.3 2.9 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Cyclin_C PF02984.14 CCC69338.1 - 1.1 9.2 9.4 1.8 8.5 0.9 3.0 2 1 0 2 2 2 0 Cyclin, C-terminal domain Reo_sigmaC PF04582.7 CCC69338.1 - 7.8 5.5 16.4 0.16 11.1 3.5 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF592 PF04574.8 CCC69339.1 - 5.7e-70 233.8 2.2 1e-69 232.9 1.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF592) SIR2 PF02146.12 CCC69339.1 - 1.1e-66 223.8 0.0 1.9e-66 223.1 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CCC69339.1 - 0.00057 19.6 0.0 0.26 11.0 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain PseudoU_synth_2 PF00849.17 CCC69340.1 - 3.6e-32 111.4 0.0 6.9e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.17 CCC69340.1 - 5.6e-17 61.2 0.0 1.1e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region S4 PF01479.20 CCC69340.1 - 0.00079 18.8 0.1 0.0028 17.0 0.0 2.0 2 0 0 2 2 2 1 S4 domain PQQ PF01011.16 CCC69340.1 - 0.0062 16.0 0.1 0.021 14.3 0.1 1.9 1 0 0 1 1 1 1 PQQ enzyme repeat Exo_endo_phos PF03372.18 CCC69341.1 - 2.7e-13 50.4 0.0 3.2e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF1187 PF06688.6 CCC69341.1 - 0.15 12.2 0.1 4.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1187) Inositol_P PF00459.20 CCC69342.1 - 2.5e-56 190.9 0.1 8.8e-56 189.1 0.1 1.7 1 1 0 1 1 1 1 Inositol monophosphatase family DEAD PF00270.24 CCC69343.1 - 4.8e-46 156.3 0.7 5.1e-45 152.9 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase DBP10CT PF08147.7 CCC69343.1 - 1.7e-21 75.7 6.2 1.7e-21 75.7 4.3 2.4 2 0 0 2 2 2 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 CCC69343.1 - 2.2e-21 75.4 0.1 6.6e-21 73.9 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3449 PF11931.3 CCC69344.1 - 2.7e-63 213.0 0.5 2.7e-63 213.0 0.4 2.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3449) zf-C2H2_jaz PF12171.3 CCC69344.1 - 3.3e-10 39.8 6.8 9.8e-09 35.1 0.2 3.5 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCC69344.1 - 3.4e-06 27.0 4.0 0.0035 17.4 0.3 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 CCC69344.1 - 0.00053 20.0 3.8 0.058 13.5 0.7 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-U1 PF06220.7 CCC69344.1 - 0.0011 18.4 0.2 0.003 17.0 0.1 1.7 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_4 PF13894.1 CCC69344.1 - 0.019 15.2 3.6 2.2 8.8 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Actin PF00022.14 CCC69345.1 - 6.3e-116 387.0 0.0 7.7e-116 386.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 CCC69345.1 - 0.004 15.7 0.0 0.025 13.1 0.0 2.0 1 1 0 1 1 1 1 MreB/Mbl protein Pkinase PF00069.20 CCC69346.1 - 2.1e-49 168.0 0.0 4.4e-49 166.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69346.1 - 7.3e-26 90.7 0.0 1.5e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCC69346.1 - 0.00035 20.3 0.0 0.1 12.2 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 CCC69346.1 - 0.006 15.9 1.1 0.006 15.9 0.8 2.3 2 1 0 2 2 2 1 RIO1 family CRT10 PF08728.5 CCC69347.1 - 3.2e-142 475.0 1.0 2.4e-141 472.1 0.7 1.9 1 1 0 1 1 1 1 CRT10 Adap_comp_sub PF00928.16 CCC69348.1 - 3.8e-75 252.3 0.4 5.6e-75 251.8 0.3 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Pribosyl_synth PF14572.1 CCC69349.1 - 5.6e-42 143.5 0.5 1.3e-41 142.3 0.3 1.7 1 1 0 1 1 1 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 CCC69349.1 - 7.9e-33 112.6 0.0 4.9e-32 110.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 CCC69349.1 - 1.6e-13 50.4 0.0 3.8e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCC69349.1 - 0.068 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase MFS_1 PF07690.11 CCC69350.1 - 2.6e-43 148.1 25.1 2.8e-37 128.2 9.9 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Gly-zipper_Omp PF13488.1 CCC69350.1 - 0.13 11.9 1.9 0.3 10.7 1.3 1.6 1 0 0 1 1 1 0 Glycine zipper NAD_Gly3P_dh_N PF01210.18 CCC69352.1 - 3.6e-52 176.2 0.2 5.9e-52 175.5 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CCC69352.1 - 1.7e-47 160.9 0.1 3.3e-47 159.9 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 CCC69352.1 - 0.0025 18.2 0.2 0.049 14.0 0.1 2.4 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Rogdi_lz PF10259.4 CCC69352.1 - 0.0033 16.5 0.3 0.005 15.9 0.2 1.2 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Semialdhyde_dh PF01118.19 CCC69352.1 - 0.0085 16.3 0.2 0.073 13.3 0.1 2.2 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 CCC69352.1 - 0.074 12.6 0.1 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Arginosuc_synth PF00764.14 CCC69353.1 - 2e-163 543.9 0.0 2.3e-163 543.7 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 CCC69353.1 - 4.6e-05 23.0 0.0 6.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 CCC69353.1 - 0.00017 20.9 0.0 0.0003 20.1 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 CCC69353.1 - 0.0039 15.7 0.0 0.0056 15.2 0.0 1.2 1 0 0 1 1 1 1 tRNA methyl transferase Peptidase_M49 PF03571.10 CCC69354.1 - 9.1e-227 753.4 0.0 1.4e-226 752.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M49 His_Phos_1 PF00300.17 CCC69355.1 - 5.6e-42 143.5 0.0 1.2e-41 142.4 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Tir_receptor_M PF03549.9 CCC69355.1 - 0.11 12.5 0.0 0.36 10.9 0.0 1.9 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) intimin-binding domain zf-C2H2 PF00096.21 CCC69356.1 - 0.00038 20.6 12.4 0.038 14.3 0.1 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC69356.1 - 0.024 14.9 11.0 0.49 10.8 0.0 3.4 4 0 0 4 4 4 0 C2H2-type zinc finger Pex16 PF08610.5 CCC69356.1 - 1 8.2 7.1 0.76 8.7 0.5 2.6 3 0 0 3 3 3 0 Peroxisomal membrane protein (Pex16) Phos_pyr_kin PF08543.7 CCC69357.1 - 1.9e-77 259.7 0.4 2.5e-77 259.4 0.3 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 CCC69357.1 - 6.1e-63 212.3 0.9 8.2e-63 211.9 0.6 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family UPF0158 PF03682.8 CCC69357.1 - 0.076 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0158) PfkB PF00294.19 CCC69357.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Oxysterol_BP PF01237.13 CCC69358.1 - 1.7e-129 431.3 0.1 3.9e-129 430.1 0.0 1.7 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 CCC69358.1 - 4.7e-14 52.4 0.2 2e-07 31.2 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCC69358.1 - 5.1e-13 48.7 0.1 5.2e-05 23.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCC69358.1 - 6.1e-12 45.7 0.1 2e-05 24.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CCC69358.1 - 4.6e-11 41.9 0.0 0.00031 20.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 CCC69358.1 - 2.9e-10 39.3 0.1 0.00015 21.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.1 CCC69358.1 - 2e-08 34.1 0.5 2.6e-07 30.6 0.1 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 CCC69358.1 - 1.4e-06 28.4 0.1 1.4e-06 28.4 0.0 2.7 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 CCC69358.1 - 1.8e-05 24.9 0.3 1.8e-05 24.9 0.2 3.4 3 0 0 3 3 3 1 Pleckstrin homology domain Pkinase PF00069.20 CCC69359.1 - 3.2e-71 239.5 0.1 7.7e-71 238.2 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69359.1 - 2.4e-52 177.5 0.0 4e-52 176.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC69359.1 - 0.00035 19.6 0.0 0.0055 15.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Actin PF00022.14 CCC69360.1 - 4.4e-161 535.7 0.0 4.9e-161 535.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 CCC69360.1 - 0.044 14.1 0.0 0.18 12.1 0.0 2.0 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Ras PF00071.17 CCC69361.1 - 1.6e-64 216.1 0.5 1.9e-64 215.9 0.4 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC69361.1 - 9.6e-20 71.2 0.1 1.5e-19 70.6 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC69361.1 - 4e-17 61.9 0.2 5.3e-17 61.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCC69361.1 - 1.5e-06 27.5 0.1 2.2e-06 27.0 0.1 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCC69361.1 - 3.6e-06 26.5 0.1 7e-06 25.5 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCC69361.1 - 7e-05 22.7 0.1 0.0001 22.2 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCC69361.1 - 0.002 17.3 0.1 0.0029 16.8 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CCC69361.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 CCC69361.1 - 0.02 14.0 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 YTH PF04146.10 CCC69361.1 - 0.037 13.6 0.2 0.051 13.1 0.1 1.2 1 0 0 1 1 1 0 YT521-B-like domain FeoB_N PF02421.13 CCC69361.1 - 0.045 13.0 0.2 0.3 10.3 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_5 PF07728.9 CCC69361.1 - 0.047 13.4 0.1 0.1 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 CCC69361.1 - 0.05 13.1 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 CCC69361.1 - 0.07 12.1 0.2 0.13 11.2 0.0 1.4 2 0 0 2 2 2 0 Septin AAA PF00004.24 CCC69361.1 - 0.079 13.1 0.1 0.47 10.6 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCC69361.1 - 0.081 12.8 0.1 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 CCC69361.1 - 0.082 13.2 0.3 0.18 12.1 0.2 1.8 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.15 CCC69361.1 - 1.5 7.4 5.5 11 4.5 0.2 2.7 1 1 1 2 2 2 0 G-protein alpha subunit RNA_pol PF00940.14 CCC69362.1 - 5.4e-163 542.1 0.0 1e-162 541.2 0.0 1.5 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 CCC69362.1 - 1.3e-86 290.7 0.1 2.3e-86 289.9 0.1 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal Mob1_phocein PF03637.12 CCC69363.1 - 1.2e-72 243.2 1.4 1.6e-72 242.8 1.0 1.2 1 0 0 1 1 1 1 Mob1/phocein family Ribosomal_L22e PF01776.12 CCC69364.1 - 4.5e-42 142.5 0.5 5.4e-42 142.3 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family DUF726 PF05277.7 CCC69365.1 - 2.2e-138 460.8 1.5 3.4e-138 460.2 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF726) B3_4 PF03483.12 CCC69366.1 - 9.3e-28 96.8 0.1 1.6e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 CCC69366.1 - 1.4e-17 63.2 0.0 3.8e-15 55.4 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetase B5 domain SLS PF14611.1 CCC69366.1 - 0.064 12.6 0.0 0.39 10.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator Pkinase PF00069.20 CCC69367.1 - 7e-59 199.0 0.0 5.5e-36 124.0 0.1 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69367.1 - 3.6e-24 85.2 0.0 3.1e-19 69.0 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 CCC69367.1 - 1.3e-07 31.5 0.0 2.7e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 CCC69367.1 - 0.001 18.0 0.0 0.011 14.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 CCC69367.1 - 0.0021 17.8 0.1 1.2 8.8 0.8 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CCC69367.1 - 0.071 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family bZIP_2 PF07716.10 CCC69368.1 - 0.0014 18.3 7.3 0.0014 18.3 5.1 1.9 1 1 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 CCC69368.1 - 0.006 16.5 9.5 0.015 15.2 6.6 1.7 1 0 0 1 1 1 1 bZIP transcription factor Qn_am_d_aIV PF09100.5 CCC69368.1 - 0.027 14.1 0.1 0.045 13.4 0.1 1.3 1 0 0 1 1 1 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain IV Aminotran_5 PF00266.14 CCC69369.1 - 3.9e-27 94.9 0.0 5e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 CCC69369.1 - 0.13 11.2 0.0 0.18 10.6 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II SHMT PF00464.14 CCC69370.1 - 7.2e-207 686.4 0.0 8.4e-207 686.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 CCC69370.1 - 0.00019 20.6 0.0 0.00036 19.7 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CCC69370.1 - 0.00096 17.9 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cut12 PF11500.3 CCC69370.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Spindle pole body formation-associated protein DUF4559 PF15112.1 CCC69370.1 - 0.16 11.1 0.4 0.28 10.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Pkinase PF00069.20 CCC69371.1 - 1.6e-24 86.5 0.0 5.6e-23 81.4 0.0 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69371.1 - 6.6e-09 35.2 0.0 7.9e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCC69371.1 - 0.0088 15.7 0.0 0.27 10.9 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family ABC_tran PF00005.22 CCC69372.1 - 6e-18 65.4 0.0 1.2e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCC69372.1 - 5.7e-10 39.6 3.9 0.00044 20.3 0.0 2.5 2 1 1 3 3 2 2 AAA domain AAA_15 PF13175.1 CCC69372.1 - 1.1e-05 24.7 0.0 0.077 12.0 0.0 2.3 1 1 1 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 CCC69372.1 - 1.1e-05 24.8 0.0 0.06 12.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 CCC69372.1 - 0.00015 21.3 0.0 0.00031 20.2 0.0 1.5 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 CCC69372.1 - 0.00043 19.7 0.0 0.0009 18.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 CCC69372.1 - 0.00077 20.2 0.3 0.0022 18.8 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 CCC69372.1 - 0.0043 17.4 0.1 0.0077 16.5 0.0 1.5 2 0 0 2 2 1 1 AAA domain Dynamin_N PF00350.18 CCC69372.1 - 0.0098 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin family FtsK_SpoIIIE PF01580.13 CCC69372.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 CCC69372.1 - 0.016 14.4 0.0 0.025 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 CCC69372.1 - 0.019 15.2 0.1 0.056 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 CCC69372.1 - 0.046 13.8 1.5 0.69 10.0 1.1 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCC69372.1 - 0.048 13.6 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 CCC69372.1 - 0.053 13.7 0.2 4.5 7.4 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CCC69372.1 - 0.056 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCC69372.1 - 0.062 13.2 0.0 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 CCC69372.1 - 0.076 12.5 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCC69372.1 - 0.076 12.8 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 CCC69372.1 - 0.083 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF3584 PF12128.3 CCC69372.1 - 0.086 10.1 0.1 0.11 9.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Miro PF08477.8 CCC69372.1 - 0.12 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Zeta_toxin PF06414.7 CCC69372.1 - 0.15 11.1 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 CCC69372.1 - 0.17 11.8 0.3 0.36 10.7 0.2 1.5 1 0 0 1 1 1 0 AAA domain RabGAP-TBC PF00566.13 CCC69373.1 - 6.8e-20 71.4 4.2 2.1e-19 69.8 2.9 1.9 1 1 0 1 1 1 1 Rab-GTPase-TBC domain STE2 PF02116.10 CCC69374.1 - 6.8e-105 350.1 25.5 8.2e-105 349.8 17.7 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF2976 PF11190.3 CCC69374.1 - 0.0073 15.8 6.3 0.0092 15.4 1.4 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2976) DUF2975 PF11188.3 CCC69374.1 - 2.9 7.6 20.6 0.21 11.2 3.5 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2975) PGAP1 PF07819.8 CCC69375.1 - 8.1e-86 287.2 0.0 1.4e-85 286.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 CCC69375.1 - 0.023 14.5 0.0 0.046 13.5 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCC69375.1 - 0.028 14.1 0.0 0.077 12.7 0.0 1.8 1 0 0 1 1 1 0 Alpha/beta hydrolase family EPL1 PF10513.4 CCC69376.1 - 1.1e-31 110.2 3.7 1.1e-31 110.2 2.6 3.9 3 1 0 3 3 3 1 Enhancer of polycomb-like DUF3835 PF12927.2 CCC69377.1 - 2.9e-17 63.3 0.3 2.9e-17 63.3 0.2 8.2 6 2 0 7 7 7 3 Domain of unknown function (DUF3835) Prefoldin PF02996.12 CCC69377.1 - 1e-14 54.1 3.8 1e-14 54.1 2.6 3.5 3 0 0 3 3 3 1 Prefoldin subunit GCR1_C PF12550.3 CCC69378.1 - 6.6e-11 41.9 1.1 2.3e-09 36.9 0.2 2.7 1 1 0 2 2 2 2 Transcriptional activator of glycolytic enzymes GATA PF00320.22 CCC69382.1 - 7.4e-16 57.2 3.4 1.7e-15 56.0 2.4 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 CCC69382.1 - 1.1e-07 31.2 2.3 5.6e-07 29.0 1.5 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 CCC69382.1 - 0.015 14.6 1.1 0.045 13.0 0.8 1.8 1 1 1 2 2 2 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 CCC69382.1 - 0.12 12.0 0.6 0.26 10.9 0.4 1.5 1 0 0 1 1 1 0 Putative transposase DNA-binding domain LSM PF01423.17 CCC69383.1 - 8.6e-17 60.4 0.2 9.6e-17 60.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain Acetyltransf_1 PF00583.19 CCC69384.1 - 2.2e-13 50.0 0.0 3.7e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 CCC69384.1 - 2.7e-06 27.4 0.1 3.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Cys_rich_CPXG PF14255.1 CCC69384.1 - 0.12 12.2 0.7 6 6.7 0.0 2.3 2 0 0 2 2 2 0 Cysteine-rich CPXCG Acetyltransf_10 PF13673.1 CCC69384.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DnaJ PF00226.26 CCC69385.1 - 1.9e-24 85.1 5.0 3.5e-24 84.3 3.5 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCC69385.1 - 1.8e-21 75.7 1.1 1.6e-15 56.7 0.1 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCC69385.1 - 7.8e-13 48.2 18.2 1.4e-12 47.4 12.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Cytochrom_c3_2 PF14537.1 CCC69385.1 - 0.00053 20.2 14.1 0.00053 20.2 9.7 2.0 2 0 0 2 2 2 1 Cytochrome c3 HypA PF01155.14 CCC69385.1 - 0.0078 15.8 8.4 0.023 14.3 0.5 2.4 1 1 1 2 2 2 2 Hydrogenase expression/synthesis hypA family PADR1 PF08063.7 CCC69385.1 - 0.069 12.5 9.7 0.46 9.9 0.7 2.6 2 1 0 2 2 2 0 PADR1 (NUC008) domain HSP9_HSP12 PF04119.7 CCC69386.1 - 2e-28 98.2 8.1 6.3e-28 96.6 1.3 2.3 2 1 0 2 2 2 2 Heat shock protein 9/12 ARHGEF5_35 PF15441.1 CCC69386.1 - 0.016 14.0 0.5 0.018 13.8 0.4 1.0 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 Polysacc_syn_2C PF08485.5 CCC69386.1 - 0.28 10.7 2.2 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal Claudin_3 PF06653.6 CCC69388.1 - 0.0019 17.9 3.1 0.0023 17.6 2.2 1.1 1 0 0 1 1 1 1 Tight junction protein, Claudin-like DUF3981 PF13139.1 CCC69388.1 - 0.099 12.6 1.1 0.13 12.3 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3981) WD40 PF00400.27 CCC69389.1 - 3.4e-49 163.0 13.5 6.2e-11 41.7 0.4 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 CCC69389.1 - 6.4e-12 45.0 2.3 6.9e-12 44.8 0.5 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 CCC69389.1 - 8.3e-09 34.8 1.0 2.6e-08 33.3 0.3 2.1 2 0 0 2 2 2 1 F-box domain PRANC PF09372.5 CCC69389.1 - 0.00016 21.5 2.3 0.00016 21.5 1.6 2.6 3 0 0 3 3 3 1 PRANC domain PQQ_2 PF13360.1 CCC69389.1 - 0.0063 16.0 0.2 0.26 10.7 0.0 3.2 3 0 0 3 3 3 1 PQQ-like domain SMC_N PF02463.14 CCC69390.1 - 7.2e-68 228.1 0.8 4e-67 225.6 0.5 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCC69390.1 - 3.4e-25 88.3 0.0 9.4e-25 86.9 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 CCC69390.1 - 5.3e-11 43.2 39.0 5.3e-11 43.2 27.0 6.8 2 2 1 3 3 3 1 AAA domain AAA_29 PF13555.1 CCC69390.1 - 2.7e-08 33.2 0.1 6.3e-08 32.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CCC69390.1 - 4.1e-07 30.2 48.9 4.9e-06 26.7 3.4 4.7 2 2 1 3 3 3 2 AAA domain ERM PF00769.14 CCC69390.1 - 0.0042 16.6 16.8 0.0042 16.6 11.7 6.9 3 2 3 6 6 6 1 Ezrin/radixin/moesin family ABC_tran PF00005.22 CCC69390.1 - 0.098 12.9 0.0 0.098 12.9 0.0 6.6 4 3 0 4 4 4 0 ABC transporter Reo_sigmaC PF04582.7 CCC69390.1 - 0.84 8.7 31.3 0.1 11.7 4.1 4.6 2 2 1 4 4 4 0 Reovirus sigma C capsid protein FUSC PF04632.7 CCC69390.1 - 2.1 6.6 3.6 4.1 5.7 0.4 2.1 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF3437 PF11919.3 CCC69391.1 - 7.8e-29 99.2 0.0 3.3e-28 97.2 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) HEAT PF02985.17 CCC69391.1 - 0.066 13.3 0.0 12 6.2 0.0 3.4 2 0 0 2 2 2 0 HEAT repeat Ras PF00071.17 CCC69392.1 - 1e-63 213.5 0.4 1.2e-63 213.3 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC69392.1 - 3.7e-20 72.5 0.1 5.6e-20 72.0 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC69392.1 - 2.9e-19 68.9 0.1 3.5e-19 68.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 CCC69392.1 - 1.3e-07 31.0 0.2 1.6e-07 30.7 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 CCC69392.1 - 2.1e-07 30.3 0.1 2.4e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 CCC69392.1 - 3.6e-06 26.5 0.1 6.1e-05 22.5 0.1 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCC69392.1 - 1e-05 25.4 0.2 1.6e-05 24.8 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 CCC69392.1 - 0.0055 16.8 0.0 0.013 15.6 0.0 1.7 1 1 1 2 2 2 1 AAA domain FeoB_N PF02421.13 CCC69392.1 - 0.008 15.4 0.1 0.15 11.3 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 CCC69392.1 - 0.015 14.5 0.0 0.023 13.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCC69392.1 - 0.017 15.1 0.2 0.033 14.1 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 CCC69392.1 - 0.023 14.1 0.2 0.078 12.5 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain MCM PF00493.18 CCC69392.1 - 0.053 12.3 0.0 0.081 11.7 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family PduV-EutP PF10662.4 CCC69392.1 - 0.075 12.5 0.0 0.48 9.9 0.0 2.0 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 CCC69392.1 - 0.09 11.6 0.1 0.2 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.24 CCC69392.1 - 0.095 12.8 0.0 0.54 10.4 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 CCC69392.1 - 0.16 10.6 1.0 2.5 6.6 0.0 2.5 1 1 1 2 2 2 0 G-protein alpha subunit VTC PF09359.5 CCC69393.1 - 4e-99 331.2 0.1 4e-99 331.2 0.0 2.3 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 CCC69393.1 - 1e-27 97.6 16.8 9.4e-17 61.6 5.4 3.8 2 1 1 3 3 3 2 SPX domain DUF202 PF02656.10 CCC69393.1 - 6.5e-10 39.0 0.6 6.5e-10 39.0 0.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1033 PF06279.6 CCC69393.1 - 0.0088 15.8 1.2 0.036 13.8 0.8 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1033) DUF4149 PF13664.1 CCC69393.1 - 0.032 14.3 1.6 0.1 12.6 1.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Bax1-I PF01027.15 CCC69393.1 - 0.059 12.9 0.7 0.089 12.3 0.5 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 MutS_V PF00488.16 CCC69394.1 - 1.1e-56 191.9 0.1 2.2e-56 190.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCC69394.1 - 1.6e-31 109.6 0.2 2.5e-30 105.7 0.1 2.4 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.12 CCC69394.1 - 3.1e-11 43.4 1.0 7.3e-11 42.2 0.1 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 CCC69394.1 - 4.2e-11 42.8 0.6 4.2e-11 42.8 0.4 2.3 2 0 0 2 2 2 1 MutS family domain IV AAA_14 PF13173.1 CCC69394.1 - 0.37 10.6 6.0 0.26 11.1 0.1 3.6 3 1 0 3 3 3 0 AAA domain DUF3441 PF11923.3 CCC69395.1 - 2.1e-34 117.4 0.6 2.1e-34 117.4 0.4 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3441) FbpA PF05833.6 CCC69395.1 - 2e-23 82.6 42.9 8.9e-23 80.5 22.3 3.8 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 CCC69395.1 - 2.3e-10 40.2 0.1 5.8e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF814) 2-Hacid_dh_C PF02826.14 CCC69396.1 - 1.1e-29 102.7 0.0 2.6e-29 101.6 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCC69396.1 - 3.1e-07 29.9 0.0 1.1e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 CCC69396.1 - 0.002 18.0 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 CCC69396.1 - 0.045 13.1 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-C2H2 PF00096.21 CCC69397.1 - 2e-09 37.2 20.5 1.3e-05 25.2 1.7 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC69397.1 - 3.7e-07 29.9 18.5 0.00095 19.3 1.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCC69397.1 - 2.9e-06 27.2 18.5 1.8e-05 24.7 3.7 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 CCC69397.1 - 4.7e-06 26.6 11.0 0.012 15.7 0.9 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCC69397.1 - 2.1e-05 24.5 12.5 0.0093 16.0 4.4 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 CCC69397.1 - 0.00047 19.8 7.6 0.12 12.1 1.8 2.5 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_6 PF13912.1 CCC69397.1 - 0.0047 16.7 6.7 0.033 14.0 0.3 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CCC69397.1 - 0.39 10.8 9.6 0.98 9.5 0.5 2.3 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Mnd1 PF03962.10 CCC69398.1 - 3.7e-29 101.7 10.0 4.1e-29 101.5 6.9 1.0 1 0 0 1 1 1 1 Mnd1 family HAUS5 PF14817.1 CCC69398.1 - 0.017 13.7 2.4 0.02 13.4 1.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Phage_GP20 PF06810.6 CCC69398.1 - 0.12 11.7 3.8 0.25 10.7 2.6 1.6 1 1 0 1 1 1 0 Phage minor structural protein GP20 Seadorna_VP6 PF07407.6 CCC69398.1 - 0.27 9.9 4.9 0.35 9.5 3.4 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF2681 PF10883.3 CCC69398.1 - 0.46 10.7 4.5 0.12 12.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ArfGap PF01412.13 CCC69399.1 - 3.2e-29 101.1 0.0 5.6e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf UBA PF00627.26 CCC69399.1 - 0.00012 21.8 0.0 0.00028 20.6 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Effector_1 PF04518.7 CCC69399.1 - 0.02 13.8 8.8 0.037 13.0 6.1 1.4 1 0 0 1 1 1 0 Effector from type III secretion system Kri1_C PF12936.2 CCC69399.1 - 0.093 12.6 0.5 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 KRI1-like family C-terminal zf-C2H2_6 PF13912.1 CCC69399.1 - 4 7.4 5.2 4.6 7.2 0.7 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3543 PF12063.3 CCC69400.1 - 3.8e-69 232.5 3.0 6.7e-69 231.7 2.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 CCC69400.1 - 4.7e-58 196.3 0.0 2e-57 194.2 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69400.1 - 1.3e-41 142.3 0.0 2.3e-41 141.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.13 CCC69400.1 - 0.062 13.1 0.2 0.31 10.9 0.0 2.3 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain APH PF01636.18 CCC69400.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Oxidored_FMN PF00724.15 CCC69401.1 - 4.8e-114 380.9 0.0 5.5e-114 380.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pkinase PF00069.20 CCC69402.1 - 5.9e-59 199.3 0.0 1e-58 198.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69402.1 - 2.4e-29 102.2 0.0 4.5e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC69402.1 - 1.1e-08 34.4 0.0 2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 CCC69402.1 - 0.00029 19.8 0.3 0.0012 17.7 0.0 2.2 2 1 1 3 3 3 1 Seadornavirus VP7 APH PF01636.18 CCC69402.1 - 0.031 14.0 0.2 0.1 12.3 0.0 1.9 2 1 0 2 2 2 0 Phosphotransferase enzyme family PUF PF00806.14 CCC69403.1 - 9.4e-57 185.4 29.1 3.8e-08 32.3 1.0 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CNH PF00780.17 CCC69404.1 - 0.0054 16.1 0.0 0.73 9.2 0.0 2.2 1 1 1 2 2 2 2 CNH domain UPF0262 PF06793.7 CCC69404.1 - 0.021 14.5 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0262) Bud13 PF09736.4 CCC69406.1 - 2.5e-24 86.1 6.0 2.5e-24 86.1 4.1 3.2 2 2 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex XRN_N PF03159.13 CCC69407.1 - 6.5e-100 333.3 0.2 1.4e-99 332.2 0.2 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Nucleoporin_FG PF13634.1 CCC69408.1 - 2.8e-36 124.1 158.9 1.4e-11 44.6 27.7 4.7 2 1 3 5 5 5 4 Nucleoporin FG repeat region zf-C4H2 PF10146.4 CCC69408.1 - 0.11 12.5 0.2 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein ATP-synt_G PF04718.10 CCC69409.1 - 5.3e-30 104.1 0.1 6.4e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit MCM PF00493.18 CCC69410.1 - 1.7e-138 460.9 0.1 2.3e-138 460.5 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCC69410.1 - 6.9e-24 84.6 4.3 1.4e-23 83.7 0.9 2.7 3 0 0 3 3 3 1 MCM N-terminal domain AAA_5 PF07728.9 CCC69410.1 - 3.2e-06 26.9 0.0 7.8e-05 22.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCC69410.1 - 1.6e-05 24.2 0.0 0.00062 18.9 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCC69410.1 - 0.0016 18.0 0.0 0.013 15.1 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) EnY2 PF10163.4 CCC69410.1 - 0.018 14.9 2.9 1.7 8.6 0.2 3.0 2 0 0 2 2 2 0 Transcription factor e(y)2 Sigma54_activat PF00158.21 CCC69410.1 - 0.07 12.5 0.1 4 6.8 0.0 3.2 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF334 PF03904.8 CCC69410.1 - 3.6 6.8 9.8 2.5 7.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF334) CAF1A PF12253.3 CCC69411.1 - 8.8e-21 73.8 13.3 8.8e-21 73.8 9.2 3.5 4 1 0 4 4 4 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 CCC69411.1 - 7.5e-15 54.8 72.1 7.5e-15 54.8 50.0 2.4 2 1 1 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-C2H2 PF00096.21 CCC69413.1 - 2.4e-09 36.9 10.1 0.00028 21.0 0.9 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC69413.1 - 3.2e-06 27.1 9.5 0.0071 16.6 0.6 2.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCC69413.1 - 9e-05 22.5 12.4 0.00017 21.6 0.3 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-met PF12874.2 CCC69413.1 - 0.0003 20.8 8.9 0.0061 16.7 0.3 2.5 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCC69413.1 - 0.0064 16.6 5.2 0.46 10.7 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CCC69413.1 - 0.15 12.3 7.6 2.4 8.5 0.4 2.7 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-BED PF02892.10 CCC69413.1 - 0.9 9.3 8.2 1.8 8.3 0.7 2.3 1 1 1 2 2 2 0 BED zinc finger RNA_pol_Rpb2_6 PF00562.23 CCC69414.1 - 4.1e-114 381.3 0.0 7.5e-114 380.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCC69414.1 - 1.3e-48 164.6 0.0 1.9e-48 164.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCC69414.1 - 5.7e-38 130.2 0.0 2.2e-37 128.3 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 CCC69414.1 - 1.8e-24 85.2 0.0 8.7e-24 83.0 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 CCC69414.1 - 8.9e-23 80.0 0.0 1.8e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 CCC69414.1 - 9.2e-16 57.8 0.0 8.9e-15 54.7 0.0 2.4 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 CCC69414.1 - 9.4e-06 25.5 0.2 2.2e-05 24.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 E1-E2_ATPase PF00122.15 CCC69415.1 - 2.6e-78 262.2 0.2 2.6e-78 262.2 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 CCC69415.1 - 9.6e-48 162.1 2.5 9.6e-48 162.1 1.7 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 CCC69415.1 - 1.2e-31 110.7 0.0 3.5e-31 109.3 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCC69415.1 - 7.7e-22 77.0 0.1 2e-21 75.7 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 CCC69415.1 - 5.8e-16 59.2 0.0 1.3e-15 58.0 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 CCC69415.1 - 1.4e-15 56.4 0.0 5e-15 54.7 0.0 2.0 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 CCC69415.1 - 1.6e-05 24.6 0.4 0.0011 18.6 0.3 2.5 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sua5_yciO_yrdC PF01300.13 CCC69416.1 - 4.9e-47 159.4 0.1 8.3e-47 158.7 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 CCC69416.1 - 4.6e-29 101.0 0.0 7.5e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding COX7C PF02935.11 CCC69417.1 - 0.1 12.4 1.1 0.26 11.0 0.8 1.6 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Zn_clus PF00172.13 CCC69418.1 - 0.0027 17.5 3.7 0.0027 17.5 2.5 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4606 PF15379.1 CCC69418.1 - 9.7 6.3 8.2 3.8 7.6 0.1 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4606) DCP1 PF06058.8 CCC69419.1 - 4.7e-16 58.9 5.3 1.6e-09 37.8 0.1 3.0 1 1 2 3 3 3 3 Dcp1-like decapping family Kelch_4 PF13418.1 CCC69419.1 - 0.083 12.6 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 Galactose oxidase, central domain Spt20 PF12090.3 CCC69420.1 - 2.1e-57 193.3 3.2 2.1e-57 193.3 2.2 3.7 3 1 0 3 3 3 1 Spt20 family Med15 PF09606.5 CCC69420.1 - 2 6.4 50.1 0.0065 14.7 7.5 2.2 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hist_deacetyl PF00850.14 CCC69422.1 - 5.4e-81 272.2 0.0 7.7e-81 271.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DMRL_synthase PF00885.14 CCC69423.1 - 2.1e-45 153.9 0.2 2.4e-45 153.7 0.1 1.0 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase RRM_5 PF13893.1 CCC69424.1 - 7.8e-08 32.0 0.3 1.7e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCC69424.1 - 8.7e-05 22.0 1.8 0.00016 21.2 0.3 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_11 PF13414.1 CCC69425.1 - 5.4e-29 99.6 31.4 1e-05 25.1 0.3 10.2 7 1 3 11 11 11 9 TPR repeat TPR_2 PF07719.12 CCC69425.1 - 6.4e-25 85.0 36.7 0.0064 16.3 0.0 13.1 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_1 PF00515.23 CCC69425.1 - 6.8e-22 76.1 47.0 0.00039 19.9 0.0 13.0 14 0 0 14 14 14 7 Tetratricopeptide repeat TPR_12 PF13424.1 CCC69425.1 - 7.8e-22 77.0 30.2 0.002 18.0 0.0 10.8 9 3 1 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.1 CCC69425.1 - 2.6e-21 75.7 20.2 0.00021 21.5 0.0 9.5 7 2 3 10 10 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 CCC69425.1 - 1.3e-19 70.3 7.3 0.0015 19.1 0.0 8.9 6 3 5 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.1 CCC69425.1 - 5.7e-18 63.7 8.0 0.012 16.2 0.1 12.4 11 2 3 14 14 12 3 Tetratricopeptide repeat Apc3 PF12895.2 CCC69425.1 - 6.5e-17 61.4 23.4 0.001 19.1 0.0 7.6 5 3 1 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCC69425.1 - 2.3e-14 51.9 40.1 0.0066 16.1 0.1 13.0 13 1 0 13 13 13 6 Tetratricopeptide repeat TPR_6 PF13174.1 CCC69425.1 - 5.5e-10 39.0 30.5 0.53 10.8 0.0 12.5 15 0 0 15 15 13 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCC69425.1 - 0.00022 20.7 26.7 0.74 9.7 0.1 10.4 12 1 0 12 12 11 2 Tetratricopeptide repeat TPR_10 PF13374.1 CCC69425.1 - 0.00053 19.8 12.4 4.3 7.3 0.1 8.0 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCC69425.1 - 0.00093 19.2 17.1 4.7 7.6 0.0 9.8 12 0 0 12 12 9 1 Tetratricopeptide repeat PEX11 PF05648.9 CCC69426.1 - 2.3e-58 197.0 2.9 2.7e-58 196.8 2.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) DUF2765 PF10963.3 CCC69426.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2765) LCM PF04072.9 CCC69427.1 - 6.5e-27 94.2 0.0 1.1e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_3 PF13415.1 CCC69427.1 - 3.8e-11 42.8 0.0 0.00097 19.2 0.0 4.2 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.1 CCC69427.1 - 4.1e-09 36.2 2.8 0.00045 20.2 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 CCC69427.1 - 5.2e-08 32.5 0.0 0.03 14.0 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 CCC69427.1 - 2.3e-07 30.2 0.1 0.0026 17.2 0.0 3.9 4 0 0 4 4 4 2 Kelch motif Kelch_5 PF13854.1 CCC69427.1 - 8.3e-07 28.8 0.2 0.0024 17.8 0.0 4.5 4 1 0 4 4 4 1 Kelch motif Kelch_2 PF07646.10 CCC69427.1 - 0.0044 16.7 2.8 1.6 8.5 0.0 4.1 4 0 0 4 4 4 1 Kelch motif CDC50 PF03381.10 CCC69428.1 - 1.9e-87 293.0 0.4 2.8e-87 292.4 0.3 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Aminotran_3 PF00202.16 CCC69429.1 - 6.3e-109 363.9 0.1 7.7e-109 363.6 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III PucR PF07905.6 CCC69429.1 - 0.031 13.8 0.0 0.17 11.4 0.0 2.2 3 0 0 3 3 3 0 Purine catabolism regulatory protein-like family Mito_carr PF00153.22 CCC69430.1 - 3.3e-68 225.4 2.9 2.6e-26 91.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Romo1 PF10247.4 CCC69430.1 - 0.13 12.4 1.5 1 9.6 0.3 2.9 2 1 1 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 BATS PF06968.8 CCC69431.1 - 1.7e-26 91.8 0.0 6.8e-26 89.9 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 CCC69431.1 - 4.8e-16 59.3 0.3 2.2e-15 57.2 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily IF4E PF01652.13 CCC69432.1 - 1.7e-57 193.5 0.2 2e-57 193.3 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E WD40 PF00400.27 CCC69433.1 - 1.7e-19 68.8 2.2 3.5e-08 33.0 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat zf-rbx1 PF12678.2 CCC69433.1 - 0.00014 21.9 3.5 0.00034 20.6 2.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CCC69433.1 - 0.014 15.4 2.1 0.014 15.4 1.5 2.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCC69433.1 - 0.015 14.9 1.0 0.015 14.9 0.7 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCC69433.1 - 0.018 14.8 6.7 0.02 14.6 3.0 2.3 2 0 0 2 2 2 0 Ring finger domain MFS_1 PF07690.11 CCC69434.1 - 8.4e-20 70.7 45.1 4.6e-13 48.6 8.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 CCC69434.1 - 0.43 10.6 7.9 0.8 9.7 0.2 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) WD40 PF00400.27 CCC69435.1 - 1.4e-42 142.0 13.5 7.8e-10 38.2 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CCC69435.1 - 2.4e-07 30.6 2.3 6.1e-05 22.8 1.0 2.9 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CCC69435.1 - 0.00045 19.0 0.4 1.6 7.3 0.1 3.7 1 1 1 2 2 2 2 Nup133 N terminal like Apc4_WD40 PF12894.2 CCC69435.1 - 0.0039 16.6 0.0 3.7 7.1 0.0 3.1 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 CCC69435.1 - 0.0064 14.6 0.6 0.76 7.8 0.1 2.4 1 1 1 2 2 2 2 Nucleoporin Nup120/160 6PF2K PF01591.13 CCC69436.1 - 5.4e-41 140.0 0.1 9.7e-41 139.2 0.1 1.4 1 0 0 1 1 1 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 CCC69436.1 - 2.6e-06 27.3 0.0 5.1e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 CCC69436.1 - 1.1e-05 24.7 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 CCC69436.1 - 0.0011 19.8 0.0 0.0028 18.4 0.0 1.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCC69436.1 - 0.0016 17.5 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin MMR_HSR1 PF01926.18 CCC69436.1 - 0.02 14.8 0.1 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 CCC69436.1 - 0.042 14.1 0.0 0.094 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 CCC69436.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCC69436.1 - 0.087 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain Med7 PF05983.6 CCC69437.1 - 1.7e-66 223.0 7.1 2e-66 222.7 4.9 1.0 1 0 0 1 1 1 1 MED7 protein YqzE PF14038.1 CCC69437.1 - 0.002 17.8 0.7 0.0096 15.6 0.3 2.2 2 0 0 2 2 2 1 YqzE-like protein cwf21 PF08312.7 CCC69437.1 - 0.017 14.9 3.8 0.017 14.9 2.6 2.4 3 1 0 3 3 3 0 cwf21 domain zf-rbx1 PF12678.2 CCC69438.1 - 1.8e-32 111.2 14.1 2.3e-32 110.9 9.8 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCC69438.1 - 1.5e-17 63.1 10.3 2e-17 62.8 7.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 CCC69438.1 - 3.7e-07 29.8 12.4 2.9e-06 27.0 8.6 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCC69438.1 - 0.00043 19.8 12.3 0.0027 17.3 8.5 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC69438.1 - 0.0098 15.9 2.6 0.0098 15.9 1.8 2.5 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCC69438.1 - 0.02 14.5 10.2 1.1 8.9 7.2 2.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 CCC69438.1 - 0.028 13.9 3.1 0.049 13.1 2.2 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CCC69438.1 - 0.036 13.7 6.1 0.32 10.7 4.2 2.5 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCC69438.1 - 0.13 12.2 0.5 0.13 12.2 0.3 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCC69438.1 - 0.13 11.9 10.9 0.92 9.2 7.6 2.3 1 1 1 2 2 2 0 zinc-RING finger domain FANCL_C PF11793.3 CCC69438.1 - 0.45 10.5 9.6 2.6 8.0 6.8 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 CCC69438.1 - 0.79 9.9 10.3 53 4.0 6.9 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 CCC69438.1 - 2.1 8.3 10.6 5.5 7.0 7.4 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain TPR_11 PF13414.1 CCC69439.1 - 3.8e-16 58.4 3.3 3.5e-11 42.5 0.1 4.4 3 1 0 3 3 3 3 TPR repeat TPR_14 PF13428.1 CCC69439.1 - 1.4e-08 34.6 0.1 0.044 14.4 0.0 5.3 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCC69439.1 - 1.3e-07 31.0 5.1 0.025 14.4 0.0 4.8 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCC69439.1 - 1.4e-06 28.1 0.3 0.041 13.8 0.0 4.6 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCC69439.1 - 4.4e-06 26.9 0.1 0.07 13.4 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCC69439.1 - 5.2e-06 26.2 7.6 0.0026 17.8 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 CCC69439.1 - 1.8e-05 25.2 3.3 0.17 12.6 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCC69439.1 - 5.9e-05 22.5 2.2 3.2 7.7 0.0 5.3 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCC69439.1 - 0.00021 20.7 2.3 1.4 8.6 0.1 4.9 4 0 0 4 4 4 1 Tetratricopeptide repeat ChAPs PF09295.5 CCC69439.1 - 0.011 14.5 0.8 0.069 11.9 0.1 2.4 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_7 PF13176.1 CCC69439.1 - 0.025 14.3 1.8 3.3 7.7 0.0 4.5 5 1 0 5 5 4 0 Tetratricopeptide repeat TPR_9 PF13371.1 CCC69439.1 - 0.027 14.2 0.4 0.34 10.7 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CCC69439.1 - 0.23 11.6 6.7 0.98 9.5 0.6 3.8 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 tRNA_anti-codon PF01336.20 CCC69440.1 - 2.2e-10 40.2 0.2 3.7e-10 39.5 0.2 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RPA_C PF08784.6 CCC69440.1 - 8e-08 32.6 0.4 4.7e-07 30.1 0.0 2.3 3 0 0 3 3 3 1 Replication protein A C terminal HTH_IclR PF09339.5 CCC69440.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 IclR helix-turn-helix domain tRNA_anti_2 PF13742.1 CCC69440.1 - 0.022 14.5 0.1 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Glyco_hydro_72 PF03198.9 CCC69441.1 - 3.4e-131 436.9 0.4 4.4e-131 436.5 0.3 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_cc PF11790.3 CCC69441.1 - 0.021 14.2 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core DNA_pol3_a_NII PF11490.3 CCC69441.1 - 0.036 13.6 0.7 1.1 8.8 0.1 2.4 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II CorA PF01544.13 CCC69442.1 - 8.6e-42 143.1 6.3 2.3e-26 92.5 0.0 2.9 2 1 1 3 3 3 2 CorA-like Mg2+ transporter protein DUF2231 PF09990.4 CCC69442.1 - 0.066 13.5 0.4 0.12 12.7 0.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2231) DUF1469 PF07332.6 CCC69442.1 - 0.15 11.8 0.2 0.28 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) UPF0220 PF05255.6 CCC69443.1 - 2.8e-67 225.0 3.3 3.2e-67 224.9 2.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF1430 PF07242.6 CCC69443.1 - 0.42 10.7 0.1 0.42 10.7 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1430) Pkinase PF00069.20 CCC69444.1 - 2.2e-57 194.2 0.0 2.8e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69444.1 - 3.2e-30 105.0 0.0 4.2e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC69444.1 - 2.3e-05 23.5 0.0 3.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCC69444.1 - 0.00046 19.9 0.0 0.00076 19.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCC69444.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 CCC69444.1 - 0.012 14.6 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L23 PF00276.15 CCC69445.1 - 1.9e-21 75.8 1.8 1.9e-21 75.8 1.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.8 CCC69445.1 - 1.8e-19 69.4 9.9 1.8e-19 69.4 6.9 2.3 2 1 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Lipoprotein_1 PF00820.14 CCC69445.1 - 0.014 14.5 0.3 0.021 13.9 0.2 1.3 1 0 0 1 1 1 0 Borrelia lipoprotein Ldh_1_N PF00056.18 CCC69446.1 - 1.3e-41 141.6 0.1 2.1e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 CCC69446.1 - 7.4e-39 133.2 0.0 1.1e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Semialdhyde_dh PF01118.19 CCC69446.1 - 0.0058 16.9 0.0 0.22 11.8 0.0 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GATA PF00320.22 CCC69447.1 - 2.9e-10 39.3 3.4 4.8e-10 38.6 2.4 1.4 1 0 0 1 1 1 1 GATA zinc finger TRM13 PF05206.9 CCC69448.1 - 4.8e-79 265.2 3.9 6.9e-79 264.7 2.7 1.2 1 0 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 CCC69448.1 - 3.3e-13 48.7 2.2 9.3e-13 47.2 1.5 1.8 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 CCC69448.1 - 7.1e-12 44.7 1.8 7.1e-12 44.7 1.3 2.2 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger UPF0020 PF01170.13 CCC69449.1 - 2.8e-13 49.8 0.0 6.5e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 CCC69449.1 - 2.5e-07 30.7 0.0 4.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 CCC69449.1 - 0.0011 18.5 0.0 0.053 12.9 0.0 2.6 2 1 0 2 2 2 1 DNA methylase RRM_1 PF00076.17 CCC69450.1 - 1.3e-36 124.0 0.8 7.2e-19 67.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC69450.1 - 2.1e-32 110.9 0.1 1.3e-15 57.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC69450.1 - 1.4e-14 53.6 0.1 6.8e-07 29.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 CCC69450.1 - 0.023 14.2 0.3 3.4 7.2 0.1 2.5 2 0 0 2 2 2 0 Ribonuclease B OB domain Nramp PF01566.13 CCC69451.1 - 2.4e-92 309.4 19.4 2.4e-92 309.4 13.4 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Dimer_Tnp_hAT PF05699.9 CCC69452.1 - 4.2e-06 26.2 0.1 1.9e-05 24.2 0.1 2.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 CCC69452.1 - 0.0095 15.6 2.2 0.023 14.4 1.5 1.7 1 0 0 1 1 1 1 BED zinc finger zinc_ribbon_5 PF13719.1 CCC69452.1 - 0.018 14.6 0.3 0.039 13.5 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Terminase_GpA PF05876.7 CCC69452.1 - 0.056 11.7 0.1 0.082 11.2 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zinc_ribbon_4 PF13717.1 CCC69452.1 - 0.07 12.8 0.8 0.17 11.6 0.5 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Ribosomal_S19e PF01090.14 CCC69453.1 - 1.9e-54 182.8 0.1 2.1e-54 182.7 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e Ribosomal_L18e PF00828.14 CCC69454.1 - 2.4e-15 57.0 0.2 4.3e-15 56.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 GCR1_C PF12550.3 CCC69456.1 - 4.5e-26 90.5 0.2 8.3e-26 89.6 0.1 1.5 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes FadA PF09403.5 CCC69456.1 - 0.059 13.3 2.2 0.064 13.2 0.0 2.0 2 0 0 2 2 2 0 Adhesion protein FadA NTP_transf_2 PF01909.18 CCC69457.1 - 3.5e-18 65.7 0.2 1.4e-17 63.7 0.0 2.2 2 0 0 2 2 2 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 CCC69457.1 - 7.3e-15 54.6 0.0 7.3e-15 54.6 0.0 2.3 2 0 0 2 2 2 1 Cid1 family poly A polymerase DNA_pol_B_palm PF14792.1 CCC69457.1 - 0.0023 17.9 0.0 0.0068 16.4 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase beta palm RF-1 PF00472.15 CCC69458.1 - 1.4e-14 53.8 0.5 2e-14 53.3 0.3 1.2 1 0 0 1 1 1 1 RF-1 domain PBD PF00786.23 CCC69459.1 - 4.4e-12 46.2 0.8 8.4e-12 45.3 0.5 1.5 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 CCC69459.1 - 7.6e-06 26.0 0.1 1.2e-05 25.4 0.1 1.3 1 0 0 1 1 1 1 PH domain FPN1 PF06963.7 CCC69459.1 - 0.045 12.1 0.0 0.048 12.0 0.0 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) STN1_2 PF09170.5 CCC69459.1 - 0.048 13.4 0.0 0.059 13.1 0.0 1.1 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 DUF348 PF03990.9 CCC69459.1 - 0.054 13.0 0.3 0.091 12.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF348) RabGAP-TBC PF00566.13 CCC69460.1 - 4.3e-45 153.8 3.2 5.9e-32 110.8 0.1 2.4 2 0 0 2 2 2 2 Rab-GTPase-TBC domain ubiquitin PF00240.18 CCC69461.1 - 5.7e-06 25.6 1.6 1.3e-05 24.4 0.1 2.0 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.1 CCC69461.1 - 0.00036 20.3 0.1 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CLU_N PF15044.1 CCC69461.1 - 0.0035 17.4 0.1 0.0067 16.5 0.1 1.5 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term DUF2407 PF10302.4 CCC69461.1 - 0.1 12.8 0.4 0.14 12.3 0.3 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Erf4 PF10256.4 CCC69462.1 - 9.2e-28 96.4 0.0 1.2e-27 96.1 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Cyclin_N PF00134.18 CCC69463.1 - 2e-12 46.8 0.1 2.9e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCC69463.1 - 2.9e-10 40.7 0.1 4.7e-10 40.0 0.1 1.3 1 0 0 1 1 1 1 Cyclin HLH PF00010.21 CCC69464.1 - 0.0015 18.1 3.7 0.014 15.0 0.3 2.5 2 0 0 2 2 2 2 Helix-loop-helix DNA-binding domain DUF1751 PF08551.5 CCC69465.1 - 1e-25 89.9 2.3 1e-25 89.9 1.6 2.5 3 0 0 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) DUF3566 PF12089.3 CCC69465.1 - 0.034 14.1 0.4 0.034 14.1 0.3 2.6 3 0 0 3 3 3 0 Transmembrane domain of unknown function (DUF3566) RseC_MucC PF04246.7 CCC69465.1 - 1.1 8.7 3.1 13 5.3 0.3 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC TadE PF07811.7 CCC69465.1 - 4.6 7.2 5.3 8.3 6.3 1.8 2.5 2 1 0 2 2 2 0 TadE-like protein Sugar_tr PF00083.19 CCC69466.1 - 5.5e-147 489.9 28.1 6.5e-147 489.7 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC69466.1 - 7.4e-31 107.1 32.5 9e-29 100.2 16.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCC69466.1 - 7.3e-06 24.4 5.2 7.3e-06 24.4 3.6 1.6 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CCC69466.1 - 0.00025 19.3 0.6 0.0005 18.3 0.4 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector DUF1673 PF07895.6 CCC69466.1 - 0.25 10.8 5.5 1.2 8.5 1.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) PTS_2-RNA PF01885.11 CCC69467.1 - 1.7e-57 193.7 1.0 2.1e-57 193.4 0.7 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family PARP PF00644.15 CCC69467.1 - 0.0049 16.3 0.8 0.01 15.2 0.5 1.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain La PF05383.12 CCC69467.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 La domain Fungal_trans PF04082.13 CCC69468.1 - 5.7e-24 84.3 4.3 5.7e-24 84.3 3.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC69468.1 - 3.4e-10 39.6 14.0 6.1e-10 38.8 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HeLo PF14479.1 CCC69468.1 - 0.11 12.2 1.5 6 6.5 0.0 2.5 2 0 0 2 2 2 0 Prion-inhibition and propagation Vps23_core PF09454.5 CCC69470.1 - 1e-22 79.4 0.4 2.8e-22 78.0 0.1 1.9 2 0 0 2 2 2 1 Vps23 core domain DUF605 PF04652.11 CCC69470.1 - 1.2 8.4 13.6 1.4 8.2 9.5 1.2 1 0 0 1 1 1 0 Vta1 like DUF4145 PF13643.1 CCC69470.1 - 1.9 8.4 4.0 2.9 7.7 1.5 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4145) ALS_ss_C PF10369.4 CCC69471.1 - 1.9e-19 69.1 0.0 7.9e-19 67.1 0.0 2.1 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 CCC69471.1 - 8.1e-12 44.3 0.6 1.7e-11 43.3 0.1 1.9 2 0 0 2 2 2 1 ACT domain ACT_5 PF13710.1 CCC69471.1 - 6.4e-09 35.5 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain Limkain-b1 PF11608.3 CCC69471.1 - 0.017 14.8 0.0 0.12 12.1 0.0 2.3 3 0 0 3 3 3 0 Limkain b1 ACT_4 PF13291.1 CCC69471.1 - 0.03 14.6 0.1 0.48 10.8 0.0 2.3 2 0 0 2 2 2 0 ACT domain DUF1325 PF07039.6 CCC69472.1 - 4.4e-34 116.9 0.0 8.2e-34 116.0 0.0 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain PilZ PF07238.9 CCC69472.1 - 0.018 15.0 0.0 0.059 13.3 0.0 1.9 1 1 0 1 1 1 0 PilZ domain DUF4537 PF15057.1 CCC69472.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Rabaptin PF03528.10 CCC69472.1 - 0.064 13.1 0.2 0.1 12.4 0.2 1.3 1 0 0 1 1 1 0 Rabaptin RRM_1 PF00076.17 CCC69473.1 - 1.2e-61 204.3 0.1 5.5e-22 77.1 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC69473.1 - 2e-39 133.4 0.0 2.5e-16 59.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC69473.1 - 1e-24 86.1 0.0 7.6e-08 32.0 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCC69473.1 - 0.0055 16.4 0.0 0.065 13.0 0.0 2.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CCC69473.1 - 0.0091 15.8 0.0 0.25 11.1 0.0 2.7 3 0 0 3 3 3 1 RNA binding motif DUF3507 PF12015.3 CCC69474.1 - 1.3e-53 181.2 0.2 2.8e-53 180.1 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3507) DUF2036 PF09724.4 CCC69475.1 - 7.9e-76 255.2 0.0 1.1e-75 254.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) Aminotran_5 PF00266.14 CCC69476.1 - 2.9e-100 335.6 0.0 3.8e-100 335.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 CCC69476.1 - 1.3e-11 44.1 0.0 2e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 CCC69476.1 - 3.4e-08 32.8 0.0 5.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CCC69476.1 - 9.9e-08 31.4 0.3 3.4e-07 29.6 0.1 1.9 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 CCC69476.1 - 2.7e-05 22.8 0.1 4.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 CCC69476.1 - 8e-05 21.0 0.1 0.00014 20.2 0.1 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Iso_dh PF00180.15 CCC69477.1 - 3.4e-129 430.7 0.0 3.8e-129 430.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RFX_DNA_binding PF02257.10 CCC69478.1 - 8.1e-35 118.8 0.1 1.7e-34 117.7 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain Pox_D5 PF03288.11 CCC69478.1 - 0.013 15.7 0.6 0.056 13.7 0.0 2.4 2 0 0 2 2 2 0 Poxvirus D5 protein-like Chorion_S16 PF05836.7 CCC69478.1 - 9.6 6.1 8.0 6.3 6.7 0.0 2.6 2 0 0 2 2 2 0 Chorion protein S16 CTDII PF01556.13 CCC69479.1 - 3.7e-24 84.4 1.3 1.1e-20 73.2 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 CCC69479.1 - 3.9e-23 80.9 1.2 6.1e-23 80.3 0.9 1.3 1 0 0 1 1 1 1 DnaJ domain DKCLD PF08068.7 CCC69480.1 - 1.3e-29 101.8 0.1 7.5e-29 99.4 0.1 2.3 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 CCC69480.1 - 2.2e-21 76.5 6.7 6.6e-20 71.7 0.0 4.0 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 CCC69480.1 - 1.5e-19 69.4 1.1 3.1e-19 68.4 0.7 1.5 1 0 0 1 1 1 1 PUA domain GAGA_bind PF06217.7 CCC69480.1 - 0.19 11.6 21.6 0.27 11.1 15.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 CCC69480.1 - 1.9 8.3 35.0 2.8 7.7 24.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 CCC69480.1 - 4.8 6.9 17.8 8.3 6.1 12.3 1.4 1 0 0 1 1 1 0 DDHD domain UvrD_C PF13361.1 CCC69481.1 - 4.9e-48 164.3 6.0 1.2e-46 159.8 0.0 3.0 2 2 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 CCC69481.1 - 4.3e-39 134.6 3.6 1.2e-20 74.1 1.4 2.8 2 2 0 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_11 PF13086.1 CCC69481.1 - 7.8e-12 45.2 0.7 4.5e-11 42.7 0.5 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCC69481.1 - 2.4e-10 40.0 0.0 1.4e-09 37.5 0.0 2.3 3 0 0 3 3 3 1 Part of AAA domain UvrD_C_2 PF13538.1 CCC69481.1 - 8.9e-10 38.6 0.0 2.9e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.13 CCC69481.1 - 9.2e-10 38.4 0.0 2.9e-05 23.6 0.0 3.2 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 CCC69481.1 - 0.0013 18.6 2.3 0.19 11.5 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCC69481.1 - 0.0061 16.7 1.6 1.8 8.7 0.1 3.0 3 1 0 3 3 3 2 AAA domain PBC PF03792.8 CCC69481.1 - 0.061 13.0 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 PBC domain AAA PF00004.24 CCC69481.1 - 3 8.0 5.1 42 4.3 0.2 3.7 2 2 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) HlyIII PF03006.15 CCC69482.1 - 1.7e-19 70.1 19.9 2.1e-19 69.8 13.8 1.1 1 0 0 1 1 1 1 Haemolysin-III related Pkinase PF00069.20 CCC69484.1 - 2.1e-64 217.1 0.0 3.5e-64 216.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69484.1 - 1.5e-35 122.5 0.0 2.4e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC69484.1 - 1.9e-08 33.6 0.0 2e-07 30.2 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 CCC69484.1 - 0.0032 16.5 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC69484.1 - 0.026 14.2 0.0 0.049 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 CCC69484.1 - 0.032 13.5 0.2 0.13 11.5 0.0 1.9 1 1 0 2 2 2 0 RIO1 family Peptidase_M16_C PF05193.16 CCC69485.1 - 4.7e-14 52.4 0.0 2.8e-12 46.6 0.0 2.8 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCC69485.1 - 5.5e-08 32.7 0.0 2.1e-07 30.8 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) tRNA-synt_1b PF00579.20 CCC69486.1 - 8e-19 67.8 0.0 1.3e-12 47.4 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) AAA_33 PF13671.1 CCC69487.1 - 1.2e-08 34.9 0.0 0.0001 22.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CCC69487.1 - 1.5e-08 35.4 0.2 1.4e-07 32.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 CCC69487.1 - 7.2e-07 29.5 0.2 3.1e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCC69487.1 - 3.6e-06 26.7 0.1 9.8e-06 25.3 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCC69487.1 - 2.6e-05 24.3 0.0 7.4e-05 22.9 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 CCC69487.1 - 5e-05 23.3 0.0 9.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 CCC69487.1 - 0.00029 20.9 0.2 0.00076 19.6 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA PF00004.24 CCC69487.1 - 0.0003 21.0 0.0 0.00058 20.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 CCC69487.1 - 0.00035 19.7 0.0 0.00068 18.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activ_2 PF14532.1 CCC69487.1 - 0.0006 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Rad17 PF03215.10 CCC69487.1 - 0.00073 18.3 0.1 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein MobB PF03205.9 CCC69487.1 - 0.0016 18.1 0.1 0.0077 15.9 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 CCC69487.1 - 0.0021 17.3 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 PRK PF00485.13 CCC69487.1 - 0.0021 17.6 0.0 0.75 9.3 0.0 2.3 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_11 PF13086.1 CCC69487.1 - 0.0026 17.4 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 CCC69487.1 - 0.0044 17.3 0.2 0.011 16.0 0.1 1.7 1 1 0 1 1 1 1 ABC transporter AAA_25 PF13481.1 CCC69487.1 - 0.0044 16.4 0.0 0.0096 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 CCC69487.1 - 0.0056 16.5 0.1 0.18 11.6 0.0 2.4 2 0 0 2 2 2 1 Adenylate kinase NB-ARC PF00931.17 CCC69487.1 - 0.0066 15.3 0.0 0.0094 14.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Sigma54_activat PF00158.21 CCC69487.1 - 0.0067 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 CCC69487.1 - 0.0075 15.0 0.0 0.014 14.1 0.0 1.4 1 1 0 1 1 1 1 TIP49 C-terminus AAA_29 PF13555.1 CCC69487.1 - 0.013 15.0 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 CCC69487.1 - 0.013 14.4 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 CCC69487.1 - 0.013 15.2 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain SRPRB PF09439.5 CCC69487.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 CCC69487.1 - 0.014 15.0 0.0 0.023 14.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 CCC69487.1 - 0.017 15.0 0.1 0.036 14.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase Mg_chelatase PF01078.16 CCC69487.1 - 0.018 14.2 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 CCC69487.1 - 0.02 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CCC69487.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 CCC69487.1 - 0.024 13.6 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Septin DNA_pol3_delta2 PF13177.1 CCC69487.1 - 0.025 14.2 0.0 0.029 14.0 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase III, delta subunit NTPase_1 PF03266.10 CCC69487.1 - 0.026 14.2 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 NTPase PPV_E1_C PF00519.12 CCC69487.1 - 0.027 13.0 0.0 0.04 12.5 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase RuvB_N PF05496.7 CCC69487.1 - 0.028 13.4 0.0 0.056 12.4 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 CCC69487.1 - 0.038 13.6 0.0 0.099 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF3987 PF13148.1 CCC69487.1 - 0.039 12.5 0.0 0.053 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) AAA_24 PF13479.1 CCC69487.1 - 0.041 13.4 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CCC69487.1 - 0.042 13.8 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CCC69487.1 - 0.051 13.0 0.0 0.095 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain APS_kinase PF01583.15 CCC69487.1 - 0.052 13.2 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_PrkA PF08298.6 CCC69487.1 - 0.053 12.2 0.0 0.1 11.2 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain DUF258 PF03193.11 CCC69487.1 - 0.054 12.6 0.1 0.13 11.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 CCC69487.1 - 0.059 12.7 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 CCC69487.1 - 0.067 12.6 0.1 0.32 10.4 0.1 1.9 1 1 1 2 2 2 0 FtsK/SpoIIIE family CobU PF02283.11 CCC69487.1 - 0.067 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase 6PF2K PF01591.13 CCC69487.1 - 0.072 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase cobW PF02492.14 CCC69487.1 - 0.074 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 CCC69487.1 - 0.087 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 ArgK protein DUF2075 PF09848.4 CCC69487.1 - 0.092 11.6 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Miro PF08477.8 CCC69487.1 - 0.1 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein Thioredoxin PF00085.15 CCC69488.1 - 5e-12 45.4 0.2 2.3e-11 43.2 0.1 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 CCC69488.1 - 0.0015 18.6 0.1 0.0041 17.1 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CCC69488.1 - 0.015 15.5 0.7 0.033 14.3 0.5 1.5 1 0 0 1 1 1 0 Thioredoxin-like domain PLDc_2 PF13091.1 CCC69489.1 - 1.3e-14 53.9 0.0 3.3e-06 26.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 CCC69489.1 - 3.2e-07 29.9 3.7 0.0036 17.0 0.2 2.8 2 1 0 2 2 2 2 Phospholipase D Active site motif PQ-loop PF04193.9 CCC69490.1 - 5.5e-05 22.6 17.2 0.0007 19.0 2.4 3.8 3 1 0 3 3 3 2 PQ loop repeat DUF3989 PF13150.1 CCC69490.1 - 0.12 11.8 0.2 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Rer1 PF03248.8 CCC69491.1 - 2.8e-73 245.2 7.4 3.1e-73 245.1 5.1 1.0 1 0 0 1 1 1 1 Rer1 family eRF1_2 PF03464.10 CCC69492.1 - 3.5e-31 108.2 0.4 6.6e-31 107.3 0.3 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CCC69492.1 - 1.6e-22 79.8 0.0 5.1e-22 78.2 0.0 1.9 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CCC69492.1 - 1.7e-11 43.7 0.7 4.1e-11 42.5 0.5 1.7 1 0 0 1 1 1 1 eRF1 domain 1 Ribosomal_L32p PF01783.18 CCC69493.1 - 3.1e-11 43.2 4.4 5.9e-11 42.3 3.0 1.5 1 0 0 1 1 1 1 Ribosomal L32p protein family RecR PF02132.10 CCC69493.1 - 0.034 13.5 1.1 0.055 12.9 0.4 1.6 2 0 0 2 2 2 0 RecR protein FMN_red PF03358.10 CCC69494.1 - 3.6e-08 33.0 0.0 5.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 CCC69494.1 - 6.1e-08 32.7 0.7 1.3e-07 31.6 0.2 1.9 2 1 0 2 2 2 1 Flavodoxin Flavodoxin_2 PF02525.12 CCC69494.1 - 0.0041 16.6 0.3 0.0087 15.5 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin-like fold Citrate_synt PF00285.16 CCC69495.1 - 9.5e-102 340.3 0.0 1.2e-101 340.0 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase DSPc PF00782.15 CCC69496.1 - 1.3e-24 86.3 1.2 5.4e-23 81.0 0.8 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCC69496.1 - 0.00053 19.3 0.0 0.00089 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCC69496.1 - 0.00081 19.4 0.0 0.0018 18.3 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Yippee-Mis18 PF03226.9 CCC69496.1 - 0.0073 16.3 1.4 0.04 13.9 0.5 2.4 2 1 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HECT_2 PF09814.4 CCC69496.1 - 0.011 14.4 0.5 0.11 11.1 0.0 2.2 2 0 0 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Eapp_C PF10238.4 CCC69496.1 - 0.027 14.3 0.1 5.7 6.8 0.0 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Elf1 PF05129.8 CCC69496.1 - 0.045 13.4 0.3 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zinc_ribbon_4 PF13717.1 CCC69496.1 - 0.25 11.0 1.9 3.3 7.4 0.1 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 CCC69496.1 - 3.8 7.1 6.0 2.7 7.6 0.0 2.7 3 0 0 3 3 3 0 zinc-ribbon domain Apc15p PF05841.6 CCC69497.1 - 2.5e-12 47.6 0.1 2.5e-12 47.6 0.0 2.5 1 1 0 2 2 2 1 Apc15p protein RNA_pol_3_Rpc31 PF11705.3 CCC69497.1 - 0.02 14.8 3.9 0.038 13.9 2.7 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF4465 PF14717.1 CCC69497.1 - 0.04 14.3 0.6 0.08 13.3 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4465) Npa1 PF11707.3 CCC69498.1 - 8e-85 284.7 3.5 8e-85 284.7 2.4 2.7 3 0 0 3 3 3 1 Ribosome 60S biogenesis N-terminal Fungal_trans PF04082.13 CCC69500.1 - 1e-27 96.6 1.1 2.2e-27 95.5 0.8 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC69500.1 - 0.0046 16.8 6.2 0.0093 15.8 4.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mmp37 PF09139.6 CCC69500.1 - 0.094 11.7 6.4 0.021 13.8 1.1 2.0 2 0 0 2 2 2 0 Mitochondrial matrix Mmp37 FF PF01846.14 CCC69501.1 - 1.2e-33 114.8 32.5 1.4e-13 50.5 0.8 7.2 6 1 1 7 7 7 4 FF domain WW PF00397.21 CCC69501.1 - 1.4e-16 59.9 10.4 2.2e-09 37.0 1.2 2.7 2 0 0 2 2 2 2 WW domain Glyco_hydro_4C PF11975.3 CCC69502.1 - 0.27 10.9 2.9 0.86 9.3 2.0 1.8 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain zf-Tim10_DDP PF02953.10 CCC69504.1 - 1.2e-23 82.1 4.6 1.4e-23 81.9 3.2 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 CCC69504.1 - 0.0026 17.2 3.5 0.0033 16.8 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Phage_connect_1 PF05135.8 CCC69504.1 - 0.077 13.1 0.1 0.096 12.8 0.1 1.1 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein G-alpha PF00503.15 CCC69505.1 - 1.1e-120 402.9 10.9 1.2e-120 402.7 7.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 CCC69505.1 - 3.5e-15 55.6 0.6 7.9e-10 38.2 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 CCC69505.1 - 0.00044 20.7 0.1 0.85 10.1 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 CCC69505.1 - 0.0013 17.8 0.5 0.2 10.7 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 CCC69505.1 - 0.085 12.4 0.1 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Ank_2 PF12796.2 CCC69506.1 - 4.3e-24 84.6 4.1 3.2e-15 56.2 0.2 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCC69506.1 - 1.9e-22 79.1 2.8 1.5e-08 34.9 0.1 3.6 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 CCC69506.1 - 2.1e-22 77.7 8.9 8.1e-07 28.5 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 CCC69506.1 - 3.3e-16 57.7 7.8 0.01 15.9 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 CCC69506.1 - 5.9e-13 48.5 2.3 1.3e-08 34.7 0.0 4.4 2 2 1 4 4 4 3 Ankyrin repeats (many copies) TUG-UBL1 PF11470.3 CCC69507.1 - 1.6e-18 66.3 0.2 8.1e-18 64.1 0.1 2.3 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 CCC69507.1 - 4.8e-14 52.1 0.7 1.9e-13 50.2 0.1 2.3 2 0 0 2 2 2 1 UBX domain PPR_2 PF13041.1 CCC69508.1 - 0.015 15.2 1.1 11 6.1 0.0 4.3 6 0 0 6 6 6 0 PPR repeat family PPR_3 PF13812.1 CCC69508.1 - 0.029 14.6 0.1 14 6.2 0.0 4.5 4 0 0 4 4 4 0 Pentatricopeptide repeat domain SURF6 PF04935.7 CCC69509.1 - 7.7e-52 175.6 61.7 7.7e-52 175.6 42.7 3.1 3 0 0 3 3 3 1 Surfeit locus protein 6 RRP14 PF15459.1 CCC69509.1 - 1.2e-18 66.9 4.4 1.2e-18 66.9 3.1 8.2 5 3 2 7 7 7 1 60S ribosome biogenesis protein Rrp14 DUF4224 PF13986.1 CCC69509.1 - 0.061 12.8 0.9 0.2 11.2 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) Kinesin PF00225.18 CCC69510.1 - 1.7e-18 66.4 8.8 7.8e-14 51.1 0.0 3.4 2 2 2 4 4 4 2 Kinesin motor domain Tht1 PF04163.7 CCC69511.1 - 4.2e-52 177.2 25.8 7.5e-52 176.4 17.9 1.3 1 1 0 1 1 1 1 Tht1-like nuclear fusion protein S_100 PF01023.14 CCC69511.1 - 0.039 13.2 0.2 0.15 11.4 0.1 2.1 2 0 0 2 2 2 0 S-100/ICaBP type calcium binding domain Latarcin PF10279.4 CCC69511.1 - 0.1 12.7 1.0 1.1 9.5 0.2 2.7 2 1 1 3 3 3 0 Latarcin precursor DUF4113 PF13438.1 CCC69512.1 - 0.14 11.7 0.3 21 4.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4113) SUR7 PF06687.7 CCC69513.1 - 1.1e-19 70.8 18.6 1.4e-19 70.4 12.9 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fasciclin PF02469.17 CCC69515.1 - 0.0017 18.3 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 Fasciclin domain XPG_N PF00752.12 CCC69516.1 - 2.6e-24 85.3 0.0 5.9e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCC69516.1 - 5.1e-20 71.3 0.0 1.5e-19 69.8 0.0 1.8 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 CCC69516.1 - 0.0012 19.0 0.0 0.005 17.0 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 CCC69516.1 - 0.0043 16.9 0.0 0.061 13.2 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif XPG_I_2 PF12813.2 CCC69516.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 XPG domain containing DUF3217 PF11506.3 CCC69516.1 - 0.032 13.9 0.4 0.17 11.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3217) NeuB PF03102.9 CCC69516.1 - 0.035 13.2 0.0 0.068 12.2 0.0 1.4 1 0 0 1 1 1 0 NeuB family Epimerase PF01370.16 CCC69517.1 - 5.5e-18 65.2 0.0 7.5e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCC69517.1 - 2.3e-11 42.9 0.0 3.1e-11 42.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCC69517.1 - 9.8e-11 41.0 0.0 2.7e-10 39.6 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CCC69517.1 - 1e-09 38.6 0.1 7e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CCC69517.1 - 1.1e-07 31.9 0.0 4.1e-07 30.0 0.0 1.9 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCC69517.1 - 0.00011 21.2 0.0 0.00042 19.3 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 CCC69517.1 - 0.0006 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 CCC69517.1 - 0.0074 15.5 0.0 0.047 12.9 0.0 2.1 2 1 1 3 3 3 1 NmrA-like family RmlD_sub_bind PF04321.12 CCC69517.1 - 0.013 14.3 0.0 1.8 7.3 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain DUF1617 PF07761.7 CCC69517.1 - 0.076 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) Ank_2 PF12796.2 CCC69518.1 - 1.1e-47 160.2 0.7 2.2e-20 72.7 0.1 3.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CCC69518.1 - 1.5e-35 119.1 0.9 5.8e-08 32.1 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 CCC69518.1 - 5.4e-30 102.7 0.4 6.9e-09 35.6 0.3 5.6 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCC69518.1 - 5.8e-26 87.9 0.1 0.00013 21.9 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 CCC69518.1 - 1.3e-25 89.2 4.2 1.1e-10 41.6 0.1 5.2 2 1 3 5 5 5 5 Ankyrin repeats (many copies) zf-DHHC PF01529.15 CCC69518.1 - 2.8e-25 88.7 1.3 2.8e-25 88.7 0.9 2.4 1 1 1 2 2 2 1 DHHC palmitoyltransferase Pex2_Pex12 PF04757.9 CCC69519.1 - 4.3e-33 114.6 6.9 9.3e-33 113.5 4.8 1.5 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 CCC69519.1 - 2.7e-08 33.5 16.2 4.9e-08 32.6 11.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCC69519.1 - 7.1e-08 32.3 17.2 1.5e-07 31.3 11.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCC69519.1 - 7.9e-07 28.6 15.4 1.4e-06 27.8 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCC69519.1 - 2.1e-06 27.2 15.4 4.5e-06 26.2 10.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCC69519.1 - 3.6e-05 23.5 17.3 8.2e-05 22.3 12.0 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 CCC69519.1 - 9e-05 22.1 12.5 0.00021 20.9 8.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CCC69519.1 - 0.00032 20.7 8.4 0.0007 19.6 5.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 CCC69519.1 - 0.00094 18.8 4.9 0.00094 18.8 3.4 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 CCC69519.1 - 0.038 13.7 10.1 0.078 12.7 7.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein U-box PF04564.10 CCC69519.1 - 0.056 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 U-box domain Katanin_con80 PF13925.1 CCC69519.1 - 0.13 12.0 0.2 0.35 10.5 0.1 1.7 2 0 0 2 2 2 0 con80 domain of Katanin zf-Apc11 PF12861.2 CCC69519.1 - 0.15 11.9 7.1 0.26 11.1 4.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 CCC69520.1 - 9e-08 31.6 7.1 9e-08 31.6 4.9 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCC69520.1 - 0.015 14.9 12.1 0.015 14.9 8.4 3.6 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) P22_Cro PF14549.1 CCC69520.1 - 0.036 13.7 0.0 0.084 12.5 0.0 1.6 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro WD40 PF00400.27 CCC69521.1 - 2e-53 176.4 24.0 1.7e-10 40.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat IKI3 PF04762.7 CCC69521.1 - 0.061 11.1 1.8 0.45 8.2 1.3 2.0 1 1 0 1 1 1 0 IKI3 family Coatomer_WDAD PF04053.9 CCC69521.1 - 0.21 10.3 3.5 0.99 8.1 0.3 2.7 2 1 1 3 3 3 0 Coatomer WD associated region tRNA-synt_1b PF00579.20 CCC69522.1 - 5.2e-71 239.1 0.0 6.6e-71 238.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) E1-E2_ATPase PF00122.15 CCC69523.1 - 3.9e-51 173.3 0.9 3.9e-51 173.3 0.7 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 CCC69523.1 - 3.1e-36 125.7 0.1 5.2e-36 125.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 CCC69523.1 - 2.6e-14 53.0 2.1 1e-12 47.9 0.7 2.5 2 0 0 2 2 2 1 Heavy-metal-associated domain HAD PF12710.2 CCC69523.1 - 6.6e-13 49.2 0.2 1.7e-12 47.9 0.1 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 CCC69523.1 - 2.5e-05 23.9 3.9 0.0012 18.4 0.1 3.1 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase CUE PF02845.11 CCC69524.1 - 0.0031 16.9 0.0 0.0075 15.7 0.0 1.7 1 0 0 1 1 1 1 CUE domain Pmp3 PF01679.12 CCC69526.1 - 2e-21 75.4 6.6 2.1e-21 75.3 4.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BTP PF05232.7 CCC69526.1 - 0.097 12.4 3.8 0.12 12.1 2.6 1.1 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family DUF2628 PF10947.3 CCC69526.1 - 0.63 9.8 3.2 0.88 9.3 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) TM2 PF05154.11 CCC69526.1 - 2.1 8.6 5.4 22 5.3 3.8 2.3 1 1 0 1 1 1 0 TM2 domain Methyltransf_28 PF02636.12 CCC69528.1 - 2.3e-05 23.8 0.0 9e-05 21.9 0.0 2.0 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Acyltransferase PF01553.16 CCC69529.1 - 5.7e-09 35.5 0.0 6e-08 32.2 0.0 2.3 1 1 0 1 1 1 1 Acyltransferase CD34_antigen PF06365.7 CCC69529.1 - 0.027 14.1 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family TRAPP PF04051.11 CCC69530.1 - 5.7e-38 129.8 0.0 7.1e-38 129.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Dsl1_N PF11988.3 CCC69530.1 - 0.034 13.0 0.4 0.052 12.4 0.0 1.6 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 N terminal TP_methylase PF00590.15 CCC69531.1 - 3.2e-37 128.2 0.1 4.8e-37 127.6 0.0 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 CCC69531.1 - 3e-05 24.1 0.0 7.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_M PF14824.1 CCC69531.1 - 0.0006 18.7 0.1 0.0014 17.5 0.0 1.7 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Sirohm_synth_C PF14823.1 CCC69531.1 - 0.018 14.3 0.0 0.77 9.1 0.0 2.5 2 0 0 2 2 2 0 Sirohaem biosynthesis protein C-terminal Hydrolase_like PF13242.1 CCC69532.1 - 4e-25 87.3 0.0 7.4e-25 86.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 CCC69532.1 - 6.3e-24 83.8 0.0 1e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 CCC69532.1 - 5.2e-05 23.5 0.1 0.26 11.5 0.0 3.1 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC69532.1 - 0.0033 17.8 0.0 0.2 12.0 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CTP_transf_2 PF01467.21 CCC69532.1 - 0.046 13.7 0.0 0.077 13.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase CIAPIN1 PF05093.8 CCC69533.1 - 1.8e-35 120.9 4.8 4.9e-35 119.6 3.3 1.7 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF2989 PF11207.3 CCC69533.1 - 0.056 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) Flavoprotein PF02441.14 CCC69534.1 - 2.7e-44 149.9 0.1 5.8e-44 148.8 0.1 1.6 1 0 0 1 1 1 1 Flavoprotein DUF674 PF05056.7 CCC69534.1 - 0.1 11.2 4.2 0.032 12.8 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF674) SOBP PF15279.1 CCC69534.1 - 5.3 7.3 20.6 1.1 9.5 11.5 1.8 2 0 0 2 2 2 0 Sine oculis-binding protein NOB1_Zn_bind PF08772.6 CCC69535.1 - 2.5e-27 94.4 0.5 5.4e-27 93.4 0.3 1.6 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN PF01850.16 CCC69535.1 - 0.0019 18.5 0.4 0.011 16.1 0.0 2.1 2 0 0 2 2 2 1 PIN domain AF1Q PF15017.1 CCC69535.1 - 0.0095 15.8 7.2 0.0095 15.8 5.0 2.4 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator zf-FCS PF06467.9 CCC69535.1 - 0.021 14.4 0.8 0.047 13.3 0.2 1.9 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-RING_3 PF14369.1 CCC69535.1 - 0.072 13.1 0.4 0.15 12.0 0.3 1.5 1 0 0 1 1 1 0 zinc-finger SGS PF05002.10 CCC69537.1 - 2.9e-29 100.6 1.3 2.9e-29 100.6 0.9 3.2 3 0 0 3 3 3 1 SGS domain CS PF04969.11 CCC69537.1 - 3.1e-15 56.4 2.0 5.6e-15 55.6 0.4 2.2 2 0 0 2 2 2 1 CS domain TPR_12 PF13424.1 CCC69537.1 - 0.0007 19.4 1.2 0.016 15.1 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCC69537.1 - 0.0032 17.0 1.3 0.047 13.3 0.4 2.3 1 1 1 2 2 2 1 TPR repeat TPR_19 PF14559.1 CCC69537.1 - 0.024 14.9 0.9 0.88 9.9 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 CCC69537.1 - 0.088 13.4 0.1 1.6 9.6 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 CCC69537.1 - 0.09 12.9 2.5 0.96 9.6 0.4 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TraS PF10624.4 CCC69537.1 - 0.16 11.5 0.2 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Plasmid conjugative transfer entry exclusion protein TraS MAP65_ASE1 PF03999.7 CCC69538.1 - 5.7e-26 91.2 15.8 7.1e-26 90.9 11.0 1.2 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Pkinase PF00069.20 CCC69539.1 - 9.9e-53 178.9 0.0 1.2e-52 178.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69539.1 - 4.9e-17 61.8 0.0 7.8e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCC69539.1 - 5.2e-07 29.6 0.0 2.9e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCC69539.1 - 0.0072 15.9 0.1 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Zip PF02535.17 CCC69540.1 - 0.041 12.8 4.8 0.051 12.5 3.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Innate_immun PF12782.2 CCC69540.1 - 0.6 9.2 8.8 1 8.5 6.1 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Ribosomal_L3 PF00297.17 CCC69541.1 - 1.2e-121 405.1 9.7 1.4e-121 404.8 6.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Trp_syntA PF00290.15 CCC69542.1 - 7.3e-95 316.3 0.3 1.1e-94 315.7 0.2 1.2 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 CCC69542.1 - 1.2e-45 156.0 1.0 1.2e-45 156.0 0.7 1.8 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 CCC69542.1 - 0.0048 16.1 0.0 0.011 14.9 0.0 1.6 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.12 CCC69542.1 - 0.044 13.0 0.5 0.39 9.9 0.1 2.5 3 0 0 3 3 3 0 PcrB family Rrn6 PF10214.4 CCC69543.1 - 3.9e-117 392.3 19.5 4.9e-117 392.0 13.5 1.0 1 0 0 1 1 1 1 RNA polymerase I-specific transcription-initiation factor Cgr1 PF03879.9 CCC69544.1 - 2.6e-37 127.3 37.7 2.9e-37 127.1 26.2 1.0 1 0 0 1 1 1 1 Cgr1 family DUF2048 PF09752.4 CCC69544.1 - 0.23 10.3 2.9 0.24 10.2 2.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) PRP1_N PF06424.7 CCC69544.1 - 0.6 10.4 13.3 0.76 10.0 9.2 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DRY_EERY PF09750.4 CCC69544.1 - 2.3 8.3 13.8 3 7.9 9.6 1.3 1 1 0 1 1 1 0 Alternative splicing regulator SprA-related PF12118.3 CCC69544.1 - 4.2 6.6 12.5 5.2 6.3 8.7 1.0 1 0 0 1 1 1 0 SprA-related family AAA_23 PF13476.1 CCC69544.1 - 5.1 7.3 14.1 6 7.1 9.8 1.3 1 0 0 1 1 1 0 AAA domain PPR_2 PF13041.1 CCC69545.1 - 4.2e-14 52.2 0.3 3e-08 33.5 0.0 3.6 2 1 1 3 3 3 2 PPR repeat family PPR PF01535.15 CCC69545.1 - 0.00034 20.4 0.0 0.21 11.6 0.0 3.2 2 0 0 2 2 2 2 PPR repeat PPR_1 PF12854.2 CCC69545.1 - 0.0028 17.1 0.0 3.5 7.1 0.0 3.6 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.1 CCC69545.1 - 0.0037 17.4 0.2 3.9 7.9 0.0 3.9 4 0 0 4 4 4 1 Pentatricopeptide repeat domain DUF2838 PF10998.3 CCC69546.1 - 1.6e-42 143.8 15.9 1.6e-42 143.8 11.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF2838) NPV_P10 PF05531.7 CCC69546.1 - 0.089 13.0 5.9 0.33 11.2 0.1 2.6 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Ribosomal_L24e PF01246.15 CCC69547.1 - 2.8e-34 116.8 0.4 2.8e-34 116.8 0.3 2.2 2 1 0 2 2 2 1 Ribosomal protein L24e RR_TM4-6 PF06459.7 CCC69547.1 - 0.83 9.4 7.6 0.96 9.2 5.2 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 U79_P34 PF03064.11 CCC69547.1 - 4.1 6.8 10.9 4.9 6.6 7.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF1279 PF06916.8 CCC69548.1 - 1.9e-27 95.3 0.1 3.3e-27 94.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) SNARE PF05739.14 CCC69549.1 - 0.00011 21.7 3.1 0.00011 21.7 2.2 3.5 4 0 0 4 4 4 1 SNARE domain DUF3153 PF11353.3 CCC69549.1 - 0.59 9.5 6.8 1.5 8.1 4.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) RVT_3 PF13456.1 CCC69550.1 - 0.014 15.1 0.0 0.56 10.0 0.0 2.8 2 1 0 2 2 2 0 Reverse transcriptase-like 5_3_exonuc_N PF02739.11 CCC69550.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain DUF2428 PF10350.4 CCC69551.1 - 9.3e-58 195.2 0.2 4e-57 193.1 0.0 2.2 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 CCC69551.1 - 0.005 16.8 0.1 0.2 11.8 0.0 3.8 5 0 0 5 5 5 1 HEAT repeat PALP PF00291.20 CCC69552.1 - 2.4e-58 197.8 0.0 3e-58 197.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 CCC69552.1 - 4.8e-12 45.4 0.0 1.3e-07 31.2 0.1 2.6 2 0 0 2 2 2 2 CBS domain Tim17 PF02466.14 CCC69552.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Enolase_C PF00113.17 CCC69553.1 - 4.1e-141 469.1 0.0 5.9e-141 468.6 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CCC69553.1 - 1.4e-55 186.7 0.2 2.2e-55 186.1 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 CCC69553.1 - 0.00011 22.1 0.1 0.00034 20.5 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 CCC69553.1 - 0.00014 20.8 0.0 0.00031 19.7 0.0 1.6 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus CSTF2_hinge PF14327.1 CCC69554.1 - 4.3e-25 87.6 1.0 4.3e-25 87.6 0.7 3.4 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 CCC69554.1 - 0.00091 18.4 4.2 0.0021 17.2 2.9 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal PEMT PF04191.8 CCC69555.1 - 3e-56 188.0 9.3 4.6e-33 113.5 0.9 3.7 4 0 0 4 4 4 2 Phospholipid methyltransferase Spt4 PF06093.8 CCC69556.1 - 0.021 14.7 0.9 3.5 7.5 0.0 3.0 1 1 1 2 2 2 0 Spt4/RpoE2 zinc finger DUF2296 PF10058.4 CCC69556.1 - 0.21 11.3 0.3 16 5.2 0.0 2.3 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) Herpes_BLRF2 PF05812.7 CCC69557.1 - 0.0018 18.0 2.7 0.0035 17.1 1.9 1.5 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein LURAP PF14854.1 CCC69557.1 - 0.0042 16.7 0.4 0.0059 16.3 0.3 1.2 1 0 0 1 1 1 1 Leucine rich adaptor protein Prp19 PF08606.6 CCC69557.1 - 0.02 14.5 2.2 0.052 13.2 1.0 2.0 2 1 0 2 2 2 0 Prp19/Pso4-like DUF4510 PF14971.1 CCC69557.1 - 0.037 14.1 0.9 0.052 13.7 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) B3_4 PF03483.12 CCC69557.1 - 0.077 12.4 0.8 0.11 11.9 0.6 1.2 1 0 0 1 1 1 0 B3/4 domain Glyco_tran_28_C PF04101.11 CCC69558.1 - 3.3e-27 95.1 0.0 2.8e-26 92.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 CCC69558.1 - 0.0015 17.7 0.0 0.002 17.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 Cmc1 PF08583.5 CCC69558.1 - 0.032 14.0 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like MIF4G PF02854.14 CCC69559.1 - 2.3e-50 170.9 0.0 3.6e-50 170.2 0.0 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 CCC69559.1 - 3e-25 87.8 0.8 3e-25 87.8 0.6 2.9 2 1 0 2 2 2 1 Eukaryotic translation initiation factor 4G1 DUF1574 PF07611.6 CCC69559.1 - 0.17 10.6 0.1 2.3 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1574) Gtr1_RagA PF04670.7 CCC69560.1 - 6.1e-56 189.1 1.0 7.9e-56 188.7 0.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SOG2 PF10428.4 CCC69560.1 - 0.12 11.0 0.0 0.16 10.6 0.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein RasGEF PF00617.14 CCC69561.1 - 7.7e-58 195.3 0.5 7.7e-58 195.3 0.4 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 CCC69561.1 - 8.7e-18 64.3 0.1 8.7e-18 64.3 0.1 3.7 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.23 CCC69561.1 - 1.6e-10 40.1 0.2 4.2e-10 38.8 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCC69561.1 - 7e-10 38.3 0.0 1.7e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCC69561.1 - 1.6e-07 30.7 0.0 3.1e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Neisseria_TspB PF05616.8 CCC69562.1 - 0.015 13.6 0.4 0.025 12.9 0.3 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Ribonucleas_3_3 PF14622.1 CCC69563.1 - 2.2e-21 76.1 0.0 2.9e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 CCC69563.1 - 0.0068 16.8 0.0 0.018 15.5 0.0 1.7 2 0 0 2 2 2 1 Ribonuclease III domain GIT_SHD PF08518.6 CCC69564.1 - 2.7e-17 61.7 1.3 7.7e-09 34.7 0.2 2.8 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Septin PF00735.13 CCC69565.1 - 4.8e-109 363.7 4.1 4.8e-109 363.7 2.9 2.1 2 0 0 2 2 2 1 Septin GTP_EFTU PF00009.22 CCC69565.1 - 9.8e-06 25.1 1.5 2.3e-05 23.9 0.3 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 CCC69565.1 - 1.5e-05 24.9 0.1 4.7e-05 23.3 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCC69565.1 - 0.00014 21.0 0.1 0.00035 19.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCC69565.1 - 0.0006 19.9 0.3 0.004 17.2 0.0 2.5 2 1 1 3 3 3 1 AAA domain AAA_29 PF13555.1 CCC69565.1 - 0.0019 17.6 0.0 0.0038 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 CCC69565.1 - 0.0023 17.9 0.1 0.0098 15.9 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Ras PF00071.17 CCC69565.1 - 0.0032 16.8 0.5 0.045 13.1 0.2 2.6 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CCC69565.1 - 0.0037 17.7 1.9 0.0048 17.3 0.0 2.2 2 1 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 CCC69565.1 - 0.0056 16.1 0.1 0.025 14.0 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_33 PF13671.1 CCC69565.1 - 0.017 15.0 0.0 0.09 12.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCC69565.1 - 0.034 14.4 0.1 0.034 14.4 0.1 2.7 3 0 0 3 3 2 0 ABC transporter Dynamin_N PF00350.18 CCC69565.1 - 1.2 8.9 15.2 0.074 12.8 1.8 3.4 2 2 0 2 2 2 0 Dynamin family IncA PF04156.9 CCC69565.1 - 3 7.3 14.6 4 6.9 9.2 1.8 2 0 0 2 2 2 0 IncA protein Exonuc_VII_L PF02601.10 CCC69565.1 - 6.4 5.8 16.0 20 4.2 10.6 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit HSP70 PF00012.15 CCC69566.1 - 3.7e-272 903.6 7.6 4.2e-272 903.4 5.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCC69566.1 - 1.1e-17 63.6 0.0 1.9e-16 59.5 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CCC69566.1 - 0.0031 17.1 0.0 0.018 14.6 0.0 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CCC69566.1 - 0.0062 15.4 1.5 0.045 12.5 0.1 2.4 3 0 0 3 3 3 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CCC69566.1 - 0.019 14.0 2.4 0.036 13.1 0.0 2.5 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase FtsA PF14450.1 CCC69566.1 - 0.051 13.4 4.0 5.7 6.8 0.4 4.2 3 1 0 3 3 3 0 Cell division protein FtsA NPR3 PF03666.8 CCC69567.1 - 1.7e-141 471.8 12.7 1.7e-141 471.8 8.8 1.7 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 MFS_1 PF07690.11 CCC69568.1 - 2.9e-40 138.0 32.9 2.9e-40 138.0 22.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 CCC69568.1 - 3.6e-09 35.3 7.2 5.9e-09 34.6 5.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.1 CCC69568.1 - 0.039 13.3 0.4 0.039 13.3 0.3 3.8 3 1 0 4 4 4 0 Domain of unknown function (DUF4131) Peptidase_M24 PF00557.19 CCC69569.1 - 7.9e-40 136.6 0.0 1.1e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 CCC69569.1 - 3e-10 40.7 0.0 9.1e-10 39.1 0.0 1.8 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain TDH PF03347.8 CCC69569.1 - 0.001 18.6 0.1 0.0022 17.5 0.1 1.4 1 0 0 1 1 1 1 Vibrio thermostable direct hemolysin Phosphodiest PF01663.17 CCC69570.1 - 7.3e-13 48.5 0.1 1.1e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.13 CCC69570.1 - 7.2e-05 22.2 1.7 0.00016 21.1 1.2 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.18 CCC69570.1 - 0.068 12.3 0.1 0.12 11.5 0.1 1.3 1 0 0 1 1 1 0 Sulfatase Myc_target_1 PF15179.1 CCC69571.1 - 8.5 5.9 9.2 0.24 10.9 0.2 2.3 2 0 0 2 2 2 0 Myc target protein 1 zf-C2H2 PF00096.21 CCC69572.1 - 3.9e-06 26.8 24.7 1.4e-05 25.1 2.3 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC69572.1 - 0.00069 19.7 13.6 0.0023 18.1 3.3 3.5 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC69572.1 - 0.00086 19.4 1.4 0.00086 19.4 0.9 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger TFIIA PF03153.8 CCC69572.1 - 0.012 15.5 37.5 0.032 14.1 10.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit U-box PF04564.10 CCC69572.1 - 0.092 12.7 1.8 18 5.3 0.1 3.3 3 0 0 3 3 3 0 U-box domain RabGAP-TBC PF00566.13 CCC69573.1 - 7.3e-05 22.3 16.0 0.0059 16.0 0.1 3.9 3 1 0 3 3 3 2 Rab-GTPase-TBC domain ENTH PF01417.15 CCC69574.1 - 7.4e-33 113.0 0.8 1.1e-32 112.5 0.6 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 CCC69574.1 - 0.00029 19.6 0.1 0.0006 18.6 0.1 1.4 1 1 0 1 1 1 1 ANTH domain VHS PF00790.14 CCC69574.1 - 0.011 15.3 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 VHS domain SAP18 PF06487.7 CCC69574.1 - 0.076 12.8 0.1 0.77 9.5 0.0 2.2 2 0 0 2 2 2 0 Sin3 associated polypeptide p18 (SAP18) ubiquitin PF00240.18 CCC69575.1 - 3.5e-169 548.5 31.3 1.6e-33 113.8 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 CCC69575.1 - 4.1e-97 317.9 28.4 6.4e-19 67.4 0.5 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCC69575.1 - 1.7e-29 101.8 15.7 0.00022 21.4 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCC69575.1 - 9.8e-27 93.6 3.0 0.0015 18.2 0.0 5.0 5 0 0 5 5 5 5 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCC69575.1 - 7.1e-17 61.2 5.2 0.16 11.8 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCC69575.1 - 1.5e-16 60.3 5.1 0.18 11.9 0.0 5.2 1 1 2 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 CCC69575.1 - 2.4e-13 49.9 0.0 2.1 8.4 0.0 5.9 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.9 CCC69575.1 - 7.7e-08 31.7 1.4 2.9 6.9 0.0 4.3 4 0 0 4 4 4 4 RNA methyltransferase TUG-UBL1 PF11470.3 CCC69575.1 - 2.2e-07 30.6 9.3 6.5 6.7 0.0 5.2 5 0 0 5 5 5 5 GLUT4 regulating protein TUG FlgD_ig PF13860.1 CCC69575.1 - 1.8e-05 24.3 8.5 19 5.0 0.0 5.3 5 0 0 5 5 5 0 FlgD Ig-like domain Big_3_3 PF13750.1 CCC69575.1 - 0.00015 21.2 0.0 67 2.8 0.0 4.9 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 CCC69575.1 - 0.0003 19.2 19.7 3.2 5.9 0.2 6.9 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain ACT_4 PF13291.1 CCC69575.1 - 0.00042 20.5 1.5 1.4e+02 2.8 0.0 5.1 5 0 0 5 5 5 0 ACT domain CTDII PF01556.13 CCC69575.1 - 0.02 14.7 19.8 11 6.0 0.2 5.4 1 1 4 5 5 5 0 DnaJ C terminal domain Tash_PEST PF07708.6 CCC69575.1 - 0.028 14.3 38.3 4.6 7.3 1.2 5.4 5 0 0 5 5 5 0 Tash protein PEST motif GABP-alpha PF11620.3 CCC69575.1 - 0.17 11.8 13.4 55 3.8 0.1 5.0 5 0 0 5 5 5 0 GA-binding protein alpha chain FERM_N PF09379.5 CCC69575.1 - 0.2 11.7 17.5 59 3.8 0.1 7.0 5 5 0 5 5 5 0 FERM N-terminal domain DUF3781 PF12636.2 CCC69575.1 - 0.85 9.6 11.2 1.4e+02 2.5 0.1 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) Ecm29 PF13001.2 CCC69576.1 - 4.8e-134 447.5 3.3 4.8e-134 447.5 2.3 1.9 2 0 0 2 2 2 1 Proteasome stabiliser HEAT PF02985.17 CCC69576.1 - 3.2e-16 57.9 14.6 0.0036 17.2 0.0 10.3 10 0 0 10 10 10 4 HEAT repeat HEAT_2 PF13646.1 CCC69576.1 - 1.6e-10 41.1 2.7 2.6 8.3 0.0 8.1 6 2 2 8 8 8 4 HEAT repeats Vac14_Fab1_bd PF12755.2 CCC69576.1 - 2.5e-07 31.0 0.3 0.037 14.4 0.0 6.3 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCC69576.1 - 2.4e-06 27.8 1.0 11 6.6 0.0 6.8 7 1 1 8 8 8 1 HEAT-like repeat Ipi1_N PF12333.3 CCC69576.1 - 0.77 9.7 6.7 2.6 8.0 0.0 4.8 5 1 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Fer2_3 PF13085.1 CCC69577.1 - 5.1e-34 116.3 0.1 9.4e-34 115.5 0.1 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 CCC69577.1 - 3.4e-10 40.1 7.9 3.4e-10 40.1 5.5 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 CCC69577.1 - 6.4e-09 35.7 6.1 6.4e-09 35.7 4.2 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 CCC69577.1 - 4e-05 23.9 3.2 4e-05 23.9 2.2 2.7 1 1 2 3 3 3 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 CCC69577.1 - 5.4e-05 23.3 5.4 0.042 14.1 0.3 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 CCC69577.1 - 0.00015 21.4 5.3 0.00015 21.4 3.7 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 CCC69577.1 - 0.002 18.4 6.3 0.002 18.4 4.4 2.4 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 CCC69577.1 - 0.0061 16.2 1.2 0.0061 16.2 0.8 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 CCC69577.1 - 6.1 7.4 8.5 1.4 9.5 0.2 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain V-SNARE_C PF12352.3 CCC69578.1 - 2.4e-15 56.3 6.1 2.4e-15 56.3 4.2 2.4 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Phage_tail_U PF06141.6 CCC69578.1 - 0.0004 20.4 0.2 1.1 9.3 0.0 2.2 2 0 0 2 2 2 2 Phage minor tail protein U RseA_N PF03872.8 CCC69578.1 - 0.0025 18.0 1.0 0.0057 16.9 0.7 1.7 1 0 0 1 1 1 1 Anti sigma-E protein RseA, N-terminal domain DUF349 PF03993.7 CCC69578.1 - 0.0038 17.3 0.7 0.014 15.5 0.3 2.1 1 1 1 2 2 2 1 Domain of Unknown Function (DUF349) SMN PF06003.7 CCC69578.1 - 0.39 9.7 2.3 0.54 9.3 1.6 1.3 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) DUF87 PF01935.12 CCC69578.1 - 2.1 8.1 11.7 3.2 7.5 4.1 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF87 Sec20 PF03908.8 CCC69578.1 - 5.9 6.6 11.5 0.26 11.0 0.8 2.9 1 1 1 3 3 3 0 Sec20 MIP PF00230.15 CCC69579.1 - 9.3e-62 208.4 5.6 1.3e-61 207.9 3.9 1.1 1 0 0 1 1 1 1 Major intrinsic protein Sigma_reg_N PF13800.1 CCC69579.1 - 7.5 6.6 6.9 1.1 9.2 0.1 3.0 3 1 1 4 4 4 0 Sigma factor regulator N-terminal FGGY_C PF02782.11 CCC69580.1 - 1.8e-70 236.5 0.2 4.9e-70 235.1 0.1 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 CCC69580.1 - 1.8e-47 161.7 0.0 2.1e-39 135.3 0.0 2.7 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain Ribosomal_L7Ae PF01248.21 CCC69581.1 - 2.9e-23 81.1 0.6 4.8e-23 80.5 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RRM_1 PF00076.17 CCC69582.1 - 1.1e-17 63.4 1.2 2.6e-08 33.3 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC69582.1 - 8.5e-08 32.0 0.1 0.0024 17.8 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CCC69582.1 - 0.47 10.9 6.6 1.2 9.6 4.5 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 DUF3628 PF12300.3 CCC69582.1 - 0.87 9.6 7.0 1.6 8.7 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3628) ABC_tran PF00005.22 CCC69583.1 - 6.3e-56 188.4 0.1 3.6e-32 111.5 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 CCC69583.1 - 4e-48 164.2 41.4 4.1e-33 114.9 7.6 4.1 4 0 0 4 4 4 3 ABC transporter transmembrane region AAA_23 PF13476.1 CCC69583.1 - 6.3e-12 46.2 4.5 3.4e-05 24.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain SMC_N PF02463.14 CCC69583.1 - 2.2e-10 40.1 2.7 1.3e-05 24.5 1.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCC69583.1 - 1.5e-07 30.8 0.1 0.0023 17.4 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CCC69583.1 - 2e-07 31.2 22.3 5.8e-07 29.7 0.3 5.3 4 3 0 4 4 2 2 AAA domain T2SE PF00437.15 CCC69583.1 - 5.5e-06 25.4 0.0 0.027 13.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 CCC69583.1 - 8.8e-06 25.6 0.2 0.063 13.2 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 CCC69583.1 - 1.2e-05 24.7 0.0 0.016 14.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCC69583.1 - 2.3e-05 24.4 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 CCC69583.1 - 2.6e-05 23.4 0.0 0.1 11.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 CCC69583.1 - 2.7e-05 24.6 0.0 0.27 11.7 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 CCC69583.1 - 4.2e-05 24.3 0.0 0.47 11.2 0.0 3.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCC69583.1 - 0.00058 20.0 0.2 2.9 8.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 CCC69583.1 - 0.00067 19.1 0.0 0.59 9.5 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 CCC69583.1 - 0.001 18.6 0.0 14 5.1 0.0 3.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein Zeta_toxin PF06414.7 CCC69583.1 - 0.0016 17.6 0.1 1.5 7.8 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_10 PF12846.2 CCC69583.1 - 0.0019 17.6 0.0 0.25 10.7 0.0 2.6 2 0 0 2 2 2 1 AAA-like domain MobB PF03205.9 CCC69583.1 - 0.0025 17.5 0.3 2.9 7.5 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 CCC69583.1 - 0.0026 17.6 3.0 0.13 12.1 0.0 3.0 3 0 0 3 3 2 1 Dynamin family Adeno_IVa2 PF02456.10 CCC69583.1 - 0.0051 15.5 0.0 0.039 12.6 0.0 2.2 2 0 0 2 2 2 1 Adenovirus IVa2 protein AAA_18 PF13238.1 CCC69583.1 - 0.0062 16.8 0.1 5.4 7.3 0.0 3.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCC69583.1 - 0.0087 16.2 1.3 6.3 7.0 0.0 3.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 CCC69583.1 - 0.012 15.0 0.5 1.2 8.6 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 CCC69583.1 - 0.023 14.5 6.0 0.67 9.7 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 TrwB_AAD_bind PF10412.4 CCC69583.1 - 0.028 13.0 0.0 7.2 5.1 0.0 2.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_19 PF13245.1 CCC69583.1 - 0.034 13.8 0.2 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 CCC69583.1 - 0.05 13.1 0.0 7.9 5.9 0.0 2.5 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 CCC69583.1 - 0.051 13.0 0.0 0.16 11.4 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_33 PF13671.1 CCC69583.1 - 0.12 12.2 0.0 11 5.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain AA_permease_2 PF13520.1 CCC69584.1 - 3.9e-60 203.5 44.0 4.9e-60 203.2 30.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCC69584.1 - 1.6e-13 49.8 39.9 2.2e-13 49.3 27.6 1.1 1 0 0 1 1 1 1 Amino acid permease TRIQK PF15168.1 CCC69584.1 - 0.58 10.1 3.6 0.74 9.7 0.0 3.0 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Cofilin_ADF PF00241.15 CCC69586.1 - 3.1e-44 149.9 0.3 3.4e-44 149.7 0.2 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein tRNA_anti-codon PF01336.20 CCC69586.1 - 0.13 12.1 0.1 0.71 9.7 0.0 2.0 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain SET PF00856.23 CCC69587.1 - 9e-06 26.0 0.0 3.6e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 SET domain AvrPto PF11592.3 CCC69587.1 - 0.086 12.6 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Central core of the bacterial effector protein AvrPto Epimerase PF01370.16 CCC69588.1 - 9.7e-15 54.6 0.0 1.3e-14 54.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCC69588.1 - 1.5e-09 36.9 0.0 2.2e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCC69588.1 - 2e-06 27.9 0.0 3.4e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Sir1 PF11603.3 CCC69590.1 - 3.4e-05 24.0 0.1 5.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Regulatory protein Sir1 Pex2_Pex12 PF04757.9 CCC69593.1 - 1.2e-14 54.2 7.0 3.3e-14 52.8 4.9 1.6 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 CCC69593.1 - 0.0012 18.5 13.7 0.0028 17.2 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ADK_lid PF05191.9 CCC69593.1 - 0.0053 16.3 1.1 0.033 13.8 0.1 2.4 2 0 0 2 2 2 1 Adenylate kinase, active site lid zf-C3HC4_2 PF13923.1 CCC69593.1 - 7.1 6.7 22.2 1.8 8.6 12.8 2.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) RhoGAP PF00620.22 CCC69594.1 - 4.7e-38 130.1 0.8 4.7e-38 130.1 0.6 2.5 3 0 0 3 3 3 1 RhoGAP domain LIM PF00412.17 CCC69594.1 - 5.1e-34 116.1 50.5 6.1e-12 45.4 4.2 4.5 4 0 0 4 4 4 4 LIM domain SID PF11778.3 CCC69595.1 - 3.7e-37 127.3 8.9 3.7e-37 127.3 6.2 3.0 3 2 0 3 3 3 1 Septation initiation DUF972 PF06156.8 CCC69595.1 - 0.49 10.7 50.4 0.25 11.7 5.2 5.9 1 1 3 4 4 4 0 Protein of unknown function (DUF972) DivIVA PF05103.8 CCC69595.1 - 0.76 9.8 40.5 0.76 9.8 4.0 3.9 2 1 1 3 3 3 0 DivIVA protein AviRa PF11599.3 CCC69595.1 - 1 8.2 6.3 5.1 6.0 0.1 2.8 2 1 2 4 4 4 0 RRNA methyltransferase AviRa DUF2797 PF10977.3 CCC69595.1 - 1.4 8.5 11.9 0.026 14.1 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2797) Herpes_BLRF2 PF05812.7 CCC69595.1 - 3 7.6 42.6 0.97 9.2 2.9 5.6 4 1 0 5 5 5 0 Herpesvirus BLRF2 protein Amidohydro_1 PF01979.15 CCC69596.1 - 6.5e-43 147.6 0.0 7.6e-43 147.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 CCC69596.1 - 1.5e-05 24.7 0.0 3.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 CCC69596.1 - 0.00068 18.9 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Hydrolase_6 PF13344.1 CCC69598.1 - 6.1e-28 96.6 0.0 1.2e-27 95.7 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC69598.1 - 1.1e-14 55.4 0.0 4.9e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCC69598.1 - 4.7e-11 42.2 0.0 9.5e-11 41.2 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.1 CCC69598.1 - 0.00029 21.1 0.1 0.12 12.6 0.1 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hpt PF01627.18 CCC69599.1 - 5.4e-13 48.7 0.2 9.6e-13 47.9 0.1 1.5 1 1 0 1 1 1 1 Hpt domain Hexokinase_2 PF03727.11 CCC69599.1 - 0.016 14.3 0.0 0.02 14.1 0.0 1.1 1 0 0 1 1 1 0 Hexokinase RabGAP-TBC PF00566.13 CCC69600.1 - 1.1e-29 103.4 19.8 1.2e-28 100.0 7.7 2.5 2 0 0 2 2 2 2 Rab-GTPase-TBC domain PAPA-1 PF04795.7 CCC69601.1 - 4.4e-13 49.7 5.7 4.4e-13 49.7 4.0 2.8 3 0 0 3 3 3 1 PAPA-1-like conserved region LIM_bind PF01803.11 CCC69602.1 - 1.3e-49 168.5 0.9 1.3e-49 168.5 0.6 2.6 3 1 0 3 3 3 1 LIM-domain binding protein FUSC_2 PF13515.1 CCC69603.1 - 9e-08 32.1 22.8 1.3e-06 28.3 4.5 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein-like ALMT PF11744.3 CCC69603.1 - 1e-07 30.9 3.4 1.5e-05 23.8 0.1 3.0 3 0 0 3 3 3 2 Aluminium activated malate transporter DUF2422 PF10337.4 CCC69603.1 - 1.9e-06 26.9 6.3 4.1e-06 25.8 3.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 CCC69603.1 - 6.8e-05 22.5 0.1 0.00015 21.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) Y_phosphatase PF00102.22 CCC69604.1 - 9.7e-55 185.4 1.3 2.7e-54 183.9 0.9 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 CCC69604.1 - 9.5e-05 21.9 0.0 0.00022 20.8 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 CCC69604.1 - 0.0099 16.1 0.0 0.027 14.7 0.0 1.8 1 1 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 CCC69604.1 - 0.066 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate HSP70 PF00012.15 CCC69605.1 - 3e-235 781.7 7.3 3.4e-235 781.5 5.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCC69605.1 - 1.3e-16 60.1 0.2 5e-15 54.9 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CCC69605.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 CCC69605.1 - 0.02 13.8 0.0 0.12 11.3 0.0 2.1 2 0 0 2 2 2 0 StbA protein Hydantoinase_A PF01968.13 CCC69605.1 - 0.022 13.8 1.4 0.88 8.6 0.1 2.9 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase DUF2603 PF10788.4 CCC69605.1 - 0.065 12.9 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) Glyco_hydro_38C PF07748.8 CCC69605.1 - 0.099 11.4 0.8 0.66 8.7 0.1 2.0 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain DUF1539 PF07560.6 CCC69605.1 - 0.15 11.9 0.3 8.2 6.3 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1539) EAP30 PF04157.11 CCC69605.1 - 0.23 10.5 3.6 0.091 11.9 0.6 1.7 2 0 0 2 2 2 0 EAP30/Vps36 family Hom_end PF05204.9 CCC69606.1 - 4.3e-41 139.2 0.0 4.7e-34 116.6 0.0 2.5 2 0 0 2 2 2 2 Homing endonuclease Hom_end_hint PF05203.11 CCC69606.1 - 3.2e-37 128.3 0.0 4.1e-37 128.0 0.0 1.1 1 0 0 1 1 1 1 Hom_end-associated Hint LAGLIDADG_3 PF14528.1 CCC69606.1 - 1.9e-08 34.3 0.0 2e-05 24.7 0.0 2.8 2 0 0 2 2 2 2 LAGLIDADG-like domain ArfGap PF01412.13 CCC69607.1 - 2.5e-34 117.5 1.0 4.8e-34 116.6 0.0 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf Septin PF00735.13 CCC69609.1 - 1.4e-73 247.3 3.4 1.4e-73 247.3 2.4 2.8 2 1 0 2 2 2 1 Septin AAA_22 PF13401.1 CCC69609.1 - 0.0012 19.0 0.0 0.0044 17.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 CCC69609.1 - 0.0024 17.7 0.1 0.016 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_32 PF13654.1 CCC69609.1 - 0.0045 15.7 8.7 0.21 10.1 4.6 2.3 2 0 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 CCC69609.1 - 0.013 15.0 0.1 0.055 12.9 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF4611 PF15387.1 CCC69609.1 - 0.022 14.8 1.3 0.022 14.8 0.9 2.1 2 0 0 2 2 1 0 Domain of unknown function (DUF4611) AAA PF00004.24 CCC69609.1 - 0.027 14.6 0.2 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 CCC69609.1 - 0.028 14.2 0.0 0.028 14.2 0.0 3.5 3 1 0 3 3 2 0 Dynamin family AIG1 PF04548.11 CCC69609.1 - 0.033 13.2 2.8 0.054 12.6 0.0 2.3 2 0 0 2 2 2 0 AIG1 family GTP_EFTU PF00009.22 CCC69609.1 - 0.038 13.4 0.1 0.43 9.9 0.0 2.8 2 2 1 3 3 3 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 CCC69609.1 - 0.039 14.2 0.0 0.039 14.2 0.0 3.1 3 1 1 4 4 4 0 AAA domain AAA_17 PF13207.1 CCC69609.1 - 0.054 14.3 3.7 0.078 13.8 0.6 3.0 2 1 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 CCC69609.1 - 0.071 12.2 0.2 0.29 10.2 0.0 2.0 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 CCC69609.1 - 0.1 12.7 0.1 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 CCC69609.1 - 0.84 9.5 0.0 0.84 9.5 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain Synaptobrevin PF00957.16 CCC69609.1 - 3.4 7.3 7.4 0.25 10.9 1.0 2.2 2 0 0 2 2 2 0 Synaptobrevin RRM_1 PF00076.17 CCC69610.1 - 1.1e-17 63.4 0.0 6.9e-16 57.6 0.0 2.9 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC69610.1 - 1.7e-08 34.3 0.0 5.3e-07 29.5 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) SUR7 PF06687.7 CCC69612.1 - 1.3e-40 139.2 12.3 1.6e-40 138.9 8.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 CCC69612.1 - 0.00016 21.6 7.6 0.0003 20.7 5.2 1.4 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 UPF0233 PF06781.7 CCC69612.1 - 0.00095 18.7 2.3 0.0042 16.6 1.6 2.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0233) Hum_adeno_E3A PF05393.6 CCC69612.1 - 0.0031 17.1 2.6 0.46 10.1 0.0 2.6 2 0 0 2 2 2 2 Human adenovirus early E3A glycoprotein Claudin_2 PF13903.1 CCC69612.1 - 0.06 13.0 12.1 0.011 15.4 5.5 1.9 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction EphA2_TM PF14575.1 CCC69612.1 - 0.25 11.7 2.3 0.9 9.9 0.0 2.6 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Tyr_Deacylase PF02580.11 CCC69614.1 - 1.6e-42 144.9 0.1 1.8e-42 144.7 0.1 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase MARVEL PF01284.18 CCC69615.1 - 2.4e-25 89.0 13.1 3.3e-25 88.5 9.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain MMPL PF03176.10 CCC69615.1 - 1.1 7.8 4.7 6 5.4 0.8 2.2 2 0 0 2 2 2 0 MMPL family Tic20 PF09685.5 CCC69615.1 - 7.6 6.5 10.4 4.6 7.2 3.6 2.1 2 0 0 2 2 2 0 Tic20-like protein Arm PF00514.18 CCC69617.1 - 1.1e-86 282.0 11.2 2.4e-14 52.5 0.1 8.3 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 CCC69617.1 - 6.6e-23 80.7 4.1 1.3e-22 79.7 2.9 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 CCC69617.1 - 1.3e-21 76.6 0.1 3.3e-06 27.2 0.0 4.9 2 2 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 CCC69617.1 - 1.3e-18 66.9 1.7 2.9e-06 27.5 0.0 5.6 4 3 2 6 6 6 3 HEAT-like repeat HEAT PF02985.17 CCC69617.1 - 7.2e-11 41.2 0.5 0.074 13.1 0.0 6.7 7 0 0 7 7 7 2 HEAT repeat Arm_2 PF04826.8 CCC69617.1 - 2e-08 33.6 0.1 0.44 9.6 0.0 4.9 1 1 3 5 5 5 4 Armadillo-like Proteasom_PSMB PF10508.4 CCC69617.1 - 4.9e-05 21.7 0.3 0.083 11.1 0.0 2.5 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 CCC69617.1 - 0.00017 21.5 0.0 0.26 11.1 0.0 3.9 4 0 0 4 4 4 1 V-ATPase subunit H HEAT_PBS PF03130.11 CCC69617.1 - 0.011 16.1 3.8 1.5 9.4 0.0 5.0 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Tim17 PF02466.14 CCC69618.1 - 8.4e-48 161.6 5.7 1e-47 161.3 3.9 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.13 CCC69618.1 - 0.066 12.4 1.2 0.18 11.0 0.0 2.0 2 1 1 3 3 3 0 Dienelactone hydrolase family JAB PF01398.16 CCC69619.1 - 1.1e-29 102.4 0.1 3.4e-29 100.9 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 CCC69619.1 - 1.3e-08 34.3 0.0 2e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 CCC69619.1 - 0.016 14.7 0.1 0.035 13.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) ELFV_dehydrog PF00208.16 CCC69620.1 - 6e-58 196.2 0.0 1.1e-57 195.3 0.0 1.5 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 CCC69620.1 - 1.2e-18 66.1 0.2 4.8e-13 47.5 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase Cadherin_2 PF08266.7 CCC69620.1 - 0.012 15.1 0.0 0.48 10.0 0.0 2.6 2 0 0 2 2 2 0 Cadherin-like ELFV_dehydrog_N PF02812.13 CCC69620.1 - 0.047 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Pkinase PF00069.20 CCC69621.1 - 3.4e-60 203.4 0.0 5.8e-60 202.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69621.1 - 1.2e-19 70.3 0.0 2.2e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCC69621.1 - 0.058 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.17 CCC69622.1 - 1.8e-05 24.2 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC69622.1 - 2.1e-05 24.4 0.0 3.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2423 PF10338.4 CCC69622.1 - 6.5 6.8 9.9 17 5.4 2.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2423) Ras PF00071.17 CCC69623.1 - 5.2e-42 142.9 0.0 7.1e-42 142.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC69623.1 - 4.1e-13 49.8 0.0 4.8e-12 46.4 0.0 2.4 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC69623.1 - 2.3e-06 26.9 0.1 5.1e-06 25.8 0.0 1.6 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCC69623.1 - 0.0057 16.1 0.0 0.033 13.6 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SHR3_chaperone PF08229.6 CCC69624.1 - 1.9e-77 258.6 2.6 2.3e-77 258.4 1.8 1.1 1 0 0 1 1 1 1 ER membrane protein SH3 DUF4231 PF14015.1 CCC69624.1 - 0.12 12.3 0.1 0.81 9.6 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Pox_A28 PF04584.9 CCC69624.1 - 0.26 11.1 1.4 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A28 family COX14 PF14880.1 CCC69624.1 - 0.92 9.1 5.1 3.5 7.3 0.0 2.8 3 0 0 3 3 3 0 Cytochrome oxidase c assembly DUF2628 PF10947.3 CCC69624.1 - 8.1 6.2 9.4 20 5.0 0.2 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2628) Vpu PF00558.14 CCC69625.1 - 0.16 11.5 0.1 0.27 10.8 0.1 1.3 1 0 0 1 1 1 0 Vpu protein Beta-APP PF03494.8 CCC69625.1 - 0.33 10.4 1.7 0.69 9.4 1.1 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) dCMP_cyt_deam_1 PF00383.17 CCC69627.1 - 2.1e-27 94.7 1.9 3.2e-27 94.1 1.3 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region TPR_20 PF14561.1 CCC69627.1 - 0.017 15.1 0.3 0.034 14.2 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat 7TMR-HDED PF07697.6 CCC69627.1 - 0.096 12.4 1.9 0.16 11.6 1.3 1.3 1 0 0 1 1 1 0 7TM-HD extracellular TPR_8 PF13181.1 CCC69627.1 - 0.1 12.4 0.2 0.24 11.2 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DNA_RNApol_7kD PF03604.8 CCC69628.1 - 1.9e-16 59.2 1.8 2.5e-16 58.8 1.3 1.2 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.2 CCC69628.1 - 0.003 17.3 0.4 0.0041 16.9 0.3 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 CCC69628.1 - 0.0049 16.5 0.2 0.0049 16.5 0.1 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family TFIIS_C PF01096.13 CCC69628.1 - 0.0061 16.1 0.8 2.9 7.6 0.1 2.3 2 0 0 2 2 2 2 Transcription factor S-II (TFIIS) Prok-RING_1 PF14446.1 CCC69628.1 - 0.007 16.0 0.7 0.0092 15.6 0.5 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 1 NCD3G PF07562.9 CCC69628.1 - 0.025 14.2 0.2 0.032 13.9 0.2 1.2 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR FYDLN_acid PF09538.5 CCC69628.1 - 0.028 14.9 0.4 0.034 14.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) C1_1 PF00130.17 CCC69628.1 - 0.037 13.7 0.4 0.053 13.2 0.3 1.2 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) A2L_zn_ribbon PF08792.5 CCC69628.1 - 0.062 12.7 0.9 0.94 9.0 0.0 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain DUF951 PF06107.6 CCC69628.1 - 0.063 12.7 1.5 1.5 8.3 0.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF951) DUF4428 PF14471.1 CCC69628.1 - 0.069 12.9 1.6 1.5 8.6 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) FYVE_2 PF02318.11 CCC69628.1 - 0.069 13.0 0.3 0.075 12.9 0.2 1.1 1 0 0 1 1 1 0 FYVE-type zinc finger DUF2318 PF10080.4 CCC69628.1 - 0.073 12.8 0.1 0.082 12.6 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) DUF2197 PF09963.4 CCC69628.1 - 0.077 12.9 2.3 6.8 6.7 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Gin PF10764.4 CCC69628.1 - 0.12 12.0 0.2 1.4 8.7 0.0 2.2 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin Zn_ribbon_recom PF13408.1 CCC69628.1 - 0.21 11.8 3.2 3.4 8.0 0.5 2.1 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain Ribosomal_L40e PF01020.12 CCC69628.1 - 0.3 10.6 2.7 0.4 10.3 1.9 1.2 1 0 0 1 1 1 0 Ribosomal L40e family Zn-ribbon_8 PF09723.5 CCC69628.1 - 0.36 10.8 3.4 1.2 9.2 2.3 1.8 1 1 0 1 1 1 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 CCC69628.1 - 0.37 10.6 2.9 1.8 8.4 2.3 1.8 1 1 1 2 2 2 0 Transposase zinc-ribbon domain TF_Zn_Ribbon PF08271.7 CCC69628.1 - 0.6 9.4 2.6 8.2 5.8 2.1 2.0 1 1 1 2 2 2 0 TFIIB zinc-binding Ribosomal_L44 PF00935.14 CCC69628.1 - 2 8.4 4.9 11 6.0 0.5 2.1 1 1 1 2 2 2 0 Ribosomal protein L44 Chs3p PF12271.3 CCC69630.1 - 2.2e-99 332.1 21.6 4.8e-99 331.0 15.0 1.4 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit Ribosomal_L44 PF00935.14 CCC69631.1 - 4.2e-34 116.3 10.7 6.1e-34 115.8 7.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Far-17a_AIG1 PF04750.9 CCC69632.1 - 4.7e-13 48.7 1.2 5.6e-13 48.5 0.8 1.1 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein SecY PF00344.15 CCC69632.1 - 0.094 11.6 1.1 0.12 11.2 0.8 1.1 1 0 0 1 1 1 0 SecY translocase Asparaginase PF00710.15 CCC69633.1 - 1e-16 60.7 4.6 6.2e-16 58.1 3.2 2.0 1 1 0 1 1 1 1 Asparaginase Arrestin_C PF02752.17 CCC69634.1 - 6.1e-22 78.1 1.1 1.8e-21 76.6 0.1 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 CCC69634.1 - 3.7e-09 36.5 0.1 2e-07 30.9 0.0 2.6 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 CCC69634.1 - 0.001 18.6 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Cryptochrome_C PF12546.3 CCC69634.1 - 2.5 8.7 6.8 2.4 8.8 0.3 2.5 2 0 0 2 2 2 0 Blue/Ultraviolet sensing protein C terminal WD40 PF00400.27 CCC69635.1 - 1.6e-07 30.9 0.5 0.00098 18.9 0.0 3.2 4 0 0 4 4 4 2 WD domain, G-beta repeat CNH PF00780.17 CCC69635.1 - 0.076 12.4 0.1 0.22 10.9 0.0 1.8 1 1 0 1 1 1 0 CNH domain DUF2457 PF10446.4 CCC69635.1 - 8 5.0 15.2 4.9 5.7 6.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) PIP5K PF01504.13 CCC69636.1 - 2.6e-65 220.0 0.4 2.6e-65 220.0 0.3 2.2 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 CCC69636.1 - 1.4e-26 93.1 0.2 1.4e-26 93.1 0.1 1.5 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 CCC69636.1 - 1.5e-16 60.0 9.6 1.5e-16 60.0 6.7 2.0 2 0 0 2 2 2 1 FYVE zinc finger Peptidase_M28 PF04389.12 CCC69637.1 - 1.1e-38 132.7 0.2 2.6e-38 131.5 0.1 1.6 2 0 0 2 2 2 1 Peptidase family M28 MAGE_N PF12440.3 CCC69638.1 - 0.21 11.9 7.0 0.094 13.0 2.7 1.9 2 0 0 2 2 2 0 Melanoma associated antigen family N terminal ABC_tran PF00005.22 CCC69639.1 - 6.5e-47 159.2 0.9 2.8e-23 82.7 0.0 3.2 3 0 0 3 3 2 2 ABC transporter ABC_tran_2 PF12848.2 CCC69639.1 - 1.9e-20 72.4 9.2 1.9e-20 72.4 6.4 2.6 3 0 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 CCC69639.1 - 4.4e-17 62.9 15.2 2.3e-06 27.8 0.0 5.3 3 2 2 5 5 4 3 AAA domain SMC_N PF02463.14 CCC69639.1 - 5.6e-11 42.0 0.0 0.00063 19.0 0.0 3.5 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCC69639.1 - 3.1e-09 37.6 1.6 0.00018 22.2 0.1 3.1 4 0 0 4 4 2 2 AAA domain AAA_16 PF13191.1 CCC69639.1 - 1.3e-07 31.8 0.2 0.0088 16.0 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 CCC69639.1 - 2.2e-07 31.2 5.8 0.039 14.2 0.1 4.7 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.1 CCC69639.1 - 5.3e-07 29.0 0.0 0.055 13.0 0.0 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain NACHT PF05729.7 CCC69639.1 - 6.7e-07 29.1 0.0 0.0051 16.4 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_15 PF13175.1 CCC69639.1 - 7.1e-07 28.6 15.8 0.061 12.3 0.0 5.5 4 1 1 6 6 6 3 AAA ATPase domain AAA_28 PF13521.1 CCC69639.1 - 1.4e-06 28.4 1.6 0.053 13.4 0.0 3.1 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 CCC69639.1 - 2e-06 27.1 0.0 0.04 13.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 CCC69639.1 - 3.1e-06 27.6 0.0 0.081 13.4 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 CCC69639.1 - 1e-05 25.7 0.5 0.35 11.0 0.1 3.4 3 1 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 CCC69639.1 - 1.2e-05 25.2 0.0 0.13 12.2 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_14 PF13173.1 CCC69639.1 - 2e-05 24.4 0.2 0.15 11.9 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA PF00004.24 CCC69639.1 - 3.9e-05 23.8 0.0 0.077 13.1 0.0 3.5 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 CCC69639.1 - 4.7e-05 22.9 0.0 0.017 14.6 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 CCC69639.1 - 5.9e-05 22.5 0.1 0.11 11.9 0.0 2.8 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CCC69639.1 - 0.0001 22.0 0.0 0.51 10.0 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 CCC69639.1 - 0.00011 21.9 0.0 0.25 11.0 0.0 2.7 2 0 0 2 2 2 2 NTPase AAA_33 PF13671.1 CCC69639.1 - 0.00014 21.7 0.0 0.2 11.5 0.0 3.0 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 CCC69639.1 - 0.00032 20.5 2.9 0.12 12.2 0.0 3.7 4 0 0 4 4 3 1 Dynamin family SbcCD_C PF13558.1 CCC69639.1 - 0.00048 19.9 0.1 2.4 8.1 0.0 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.17 CCC69639.1 - 0.00051 20.1 0.0 0.5 10.5 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.1 CCC69639.1 - 0.00059 20.2 26.5 0.4 10.9 0.0 5.1 5 0 0 5 5 5 2 AAA domain ArgK PF03308.11 CCC69639.1 - 0.00095 18.0 0.0 0.2 10.3 0.0 2.6 2 0 0 2 2 2 1 ArgK protein NB-ARC PF00931.17 CCC69639.1 - 0.0014 17.5 0.0 0.87 8.3 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_5 PF07728.9 CCC69639.1 - 0.0022 17.7 0.1 3.1 7.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CCC69639.1 - 0.0052 15.9 0.1 0.88 8.6 0.0 2.7 3 0 0 3 3 2 1 Zeta toxin AAA_25 PF13481.1 CCC69639.1 - 0.0064 15.9 0.0 4 6.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 CCC69639.1 - 0.0089 15.3 1.0 0.15 11.3 0.0 2.7 3 0 0 3 3 3 1 Poxvirus A32 protein AAA_10 PF12846.2 CCC69639.1 - 0.0094 15.4 1.5 2.1 7.6 0.0 3.0 2 2 0 2 2 2 1 AAA-like domain cobW PF02492.14 CCC69639.1 - 0.012 15.0 0.1 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 CCC69639.1 - 0.015 14.2 0.0 0.14 11.0 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein FeoB_N PF02421.13 CCC69639.1 - 0.021 14.1 0.0 5.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 CCC69639.1 - 0.029 14.0 10.1 0.046 13.4 0.0 3.2 4 0 0 4 4 3 0 Archaeal ATPase SRP54 PF00448.17 CCC69639.1 - 0.035 13.5 0.0 2.2 7.6 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 CCC69639.1 - 0.044 13.2 3.5 0.86 9.0 0.0 3.3 3 1 1 4 4 4 0 FtsK/SpoIIIE family Ras PF00071.17 CCC69639.1 - 0.062 12.6 0.8 7 6.0 0.0 3.2 3 0 0 3 3 3 0 Ras family UPF0079 PF02367.12 CCC69639.1 - 0.093 12.3 0.1 1 8.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2813 PF11398.3 CCC69639.1 - 0.15 11.1 6.0 0.51 9.3 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2813) DUF87 PF01935.12 CCC69639.1 - 0.61 9.8 0.0 0.61 9.8 0.0 4.5 4 1 1 5 5 5 0 Domain of unknown function DUF87 RNB PF00773.14 CCC69640.1 - 5.6e-92 308.4 0.2 2.5e-91 306.3 0.0 1.9 2 0 0 2 2 2 1 RNB domain PIN_4 PF13638.1 CCC69640.1 - 1.9e-13 50.6 1.2 4.7e-13 49.3 0.9 1.6 1 0 0 1 1 1 1 PIN domain OB_RNB PF08206.6 CCC69640.1 - 0.099 12.1 0.0 0.34 10.4 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease B OB domain UCH PF00443.24 CCC69641.1 - 3.9e-52 176.9 5.6 5.2e-52 176.6 3.9 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC69641.1 - 1.1e-18 67.6 10.2 2e-18 66.8 7.1 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 CCC69641.1 - 7.2e-05 22.1 0.1 0.0004 19.7 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin family DUF1690 PF07956.6 CCC69642.1 - 2.7e-36 124.6 14.1 3.1e-36 124.4 9.8 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) InvH PF04741.7 CCC69642.1 - 0.017 15.0 2.0 0.021 14.6 1.4 1.2 1 0 0 1 1 1 0 InvH outer membrane lipoprotein DUF3510 PF12022.3 CCC69642.1 - 0.052 13.6 3.0 0.071 13.2 1.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3510) AKNA PF12443.3 CCC69642.1 - 0.34 10.9 5.7 0.37 10.8 3.2 1.8 1 1 0 1 1 1 0 AT-hook-containing transcription factor WHIM1 PF15612.1 CCC69643.1 - 0.00081 19.2 0.0 0.0029 17.4 0.0 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DUF349 PF03993.7 CCC69643.1 - 0.0019 18.2 1.9 0.0085 16.2 1.3 2.1 1 0 0 1 1 1 1 Domain of Unknown Function (DUF349) FAD_oxidored PF12831.2 CCC69643.1 - 0.23 10.5 0.3 0.37 9.7 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pkinase PF00069.20 CCC69644.1 - 7.7e-71 238.2 0.0 1.2e-70 237.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69644.1 - 3.8e-39 134.3 0.0 6.9e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CCC69644.1 - 0.0068 15.7 0.2 0.016 14.5 0.0 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 CCC69644.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCC69644.1 - 0.025 13.5 0.0 0.15 10.9 0.0 2.1 1 1 1 2 2 2 0 Kinase-like ABC1 PF03109.11 CCC69644.1 - 0.033 14.1 0.0 0.1 12.5 0.0 1.8 2 0 0 2 2 2 0 ABC1 family Glycogen_syn PF05693.8 CCC69645.1 - 0 1110.6 0.0 0 1110.5 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 CCC69645.1 - 1.2e-08 34.5 0.0 7.2e-06 25.5 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 CCC69645.1 - 5.5e-05 23.3 0.0 0.0001 22.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_transf_5 PF08323.6 CCC69645.1 - 0.00013 21.5 0.0 0.00024 20.6 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain SH3BGR PF04908.10 CCC69646.1 - 0.00037 20.3 0.0 0.018 14.9 0.0 3.5 2 0 0 2 2 2 1 SH3-binding, glutamic acid-rich protein Ferric_reduct PF01794.14 CCC69647.1 - 4e-16 59.2 9.4 4e-16 59.2 6.5 2.3 1 1 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CCC69647.1 - 1.5e-09 37.9 0.0 3e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CCC69647.1 - 0.0012 18.6 0.1 0.0027 17.5 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain OCD_Mu_crystall PF02423.10 CCC69648.1 - 2.2e-06 26.6 0.0 7.2e-06 24.9 0.0 1.7 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family RF-1 PF00472.15 CCC69650.1 - 2.3e-39 133.6 4.2 6e-39 132.3 2.9 1.6 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 CCC69650.1 - 2.1e-30 104.8 2.1 2.2e-30 104.7 0.0 2.1 3 0 0 3 3 3 1 PCRF domain FTA4 PF13093.1 CCC69650.1 - 0.0058 16.0 6.3 0.3 10.4 1.5 2.5 2 1 0 2 2 2 2 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Mating_N PF12731.2 CCC69650.1 - 0.12 12.2 2.9 0.14 12.0 1.0 1.9 2 1 0 2 2 2 0 Mating-type protein beta 1 Erp_C PF06780.6 CCC69650.1 - 0.39 10.5 3.4 12 5.7 0.0 2.5 2 0 0 2 2 2 0 Erp protein C-terminus XhlA PF10779.4 CCC69650.1 - 2.2 8.2 5.0 2.4 8.1 2.2 2.1 2 0 0 2 2 2 0 Haemolysin XhlA AAA_23 PF13476.1 CCC69650.1 - 2.2 8.5 8.7 6.7 6.9 2.9 2.2 2 0 0 2 2 2 0 AAA domain Atg14 PF10186.4 CCC69650.1 - 3.8 6.3 9.1 2.3 7.1 1.1 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 UPF0029 PF01205.14 CCC69651.1 - 4.7e-31 106.7 0.0 7.4e-31 106.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Pkinase PF00069.20 CCC69652.1 - 1.8e-62 210.8 0.5 2.9e-62 210.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69652.1 - 9.1e-25 87.2 0.0 3.2e-24 85.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC69652.1 - 4e-05 22.7 0.2 0.11 11.4 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 CCC69652.1 - 0.005 15.9 1.0 0.0078 15.2 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC69652.1 - 0.026 14.2 0.2 0.071 12.8 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family LT-IIB PF06453.6 CCC69652.1 - 0.057 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) Glyco_hydro_38 PF01074.17 CCC69653.1 - 9.5e-84 280.8 0.1 1.6e-83 280.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 CCC69653.1 - 2.9e-63 214.2 4.4 4.1e-63 213.7 3.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 CCC69653.1 - 3.4e-24 84.8 0.0 6.6e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Prenyltrans PF00432.16 CCC69654.1 - 1.3e-28 98.2 5.5 1.4e-07 30.9 0.0 5.6 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 CCC69654.1 - 1.1e-15 58.0 0.0 9.9e-05 22.7 0.0 3.8 1 1 2 4 4 4 4 Prenyltransferase-like A2M_comp PF07678.9 CCC69654.1 - 0.00071 18.8 0.0 0.12 11.5 0.0 3.0 2 2 1 3 3 3 1 A-macroglobulin complement component Prenyltrans_1 PF13243.1 CCC69654.1 - 0.084 12.8 0.0 0.56 10.2 0.0 2.4 2 1 1 3 3 3 0 Prenyltransferase-like ACPS PF01648.15 CCC69655.1 - 2.4e-12 46.7 0.0 3.5e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily DUF4105 PF13387.1 CCC69655.1 - 0.04 13.0 0.1 0.084 12.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4105) DUF3874 PF12990.2 CCC69655.1 - 0.12 12.4 0.2 6.7 6.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknonw function from B. Theta Gene description (DUF3874) Pex14_N PF04695.8 CCC69656.1 - 1.6e-34 118.8 0.0 1.6e-34 118.8 0.0 2.6 3 0 0 3 3 3 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Baculo_PEP_C PF04513.7 CCC69656.1 - 0.00013 21.8 9.5 0.00026 20.8 6.6 1.5 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 CCC69656.1 - 0.00061 19.5 0.9 0.00061 19.5 0.7 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1664) Phage_GPO PF05929.6 CCC69656.1 - 0.0057 15.9 1.0 0.01 15.0 0.7 1.5 1 0 0 1 1 1 1 Phage capsid scaffolding protein (GPO) serine peptidase Reo_sigmaC PF04582.7 CCC69656.1 - 0.016 14.3 4.6 0.029 13.5 3.2 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Exonuc_VII_L PF02601.10 CCC69656.1 - 0.022 13.9 4.6 0.036 13.2 3.2 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF342 PF03961.8 CCC69656.1 - 0.029 12.8 7.6 0.047 12.1 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) V_ATPase_I PF01496.14 CCC69656.1 - 0.057 11.2 7.0 0.082 10.7 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nsp1_C PF05064.8 CCC69656.1 - 0.078 12.6 11.2 1.5 8.4 2.0 2.7 1 1 1 2 2 2 0 Nsp1-like C-terminal region Prominin PF05478.6 CCC69656.1 - 0.092 10.2 3.9 0.13 9.8 2.7 1.1 1 0 0 1 1 1 0 Prominin Vps51 PF08700.6 CCC69656.1 - 0.14 11.9 9.6 0.063 13.1 4.4 2.2 2 0 0 2 2 2 0 Vps51/Vps67 IFT57 PF10498.4 CCC69656.1 - 0.19 10.4 15.2 0.34 9.6 10.5 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 LUC7 PF03194.10 CCC69656.1 - 0.22 11.0 5.3 0.32 10.4 3.7 1.3 1 0 0 1 1 1 0 LUC7 N_terminus CCDC-167 PF15188.1 CCC69656.1 - 0.29 11.1 12.5 1.3 9.0 0.2 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Atg14 PF10186.4 CCC69656.1 - 0.4 9.5 7.8 0.3 9.9 4.2 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Vps53_N PF04100.7 CCC69656.1 - 0.42 9.3 10.9 0.62 8.7 7.6 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal IF-2B PF01008.12 CCC69656.1 - 0.45 9.4 5.4 0.82 8.6 3.7 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family CHD5 PF04420.9 CCC69656.1 - 0.52 9.9 6.3 0.26 10.9 1.8 2.1 1 1 1 2 2 2 0 CHD5-like protein FlgN PF05130.7 CCC69656.1 - 0.54 10.5 11.5 1.1 9.5 7.9 1.5 1 0 0 1 1 1 0 FlgN protein zf-C4H2 PF10146.4 CCC69656.1 - 0.73 9.8 10.5 0.26 11.2 5.6 1.5 2 0 0 2 2 1 0 Zinc finger-containing protein DUF1043 PF06295.7 CCC69656.1 - 1.1 8.9 9.3 0.94 9.1 0.2 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1043) APG6 PF04111.7 CCC69656.1 - 1.2 8.0 16.0 2.3 7.2 11.1 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF3573 PF12097.3 CCC69656.1 - 1.9 6.9 7.4 2.9 6.3 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Syntaxin-6_N PF09177.6 CCC69656.1 - 2.1 8.7 8.6 3.7 8.0 4.5 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Tup_N PF08581.5 CCC69656.1 - 2.5 8.3 12.9 2.3 8.4 7.5 2.1 2 0 0 2 2 2 0 Tup N-terminal NPV_P10 PF05531.7 CCC69656.1 - 4.8 7.4 11.1 8.2 6.7 2.6 2.8 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4200 PF13863.1 CCC69656.1 - 7.1 6.6 17.3 4.5 7.2 9.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) LMBR1 PF04791.11 CCC69656.1 - 7.6 4.9 5.4 9.8 4.6 3.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Allexi_40kDa PF05549.6 CCC69656.1 - 9.3 5.4 15.6 3.6 6.8 7.3 2.6 3 1 0 3 3 3 0 Allexivirus 40kDa protein Cep57_CLD_2 PF14197.1 CCC69656.1 - 9.8 6.2 13.7 19 5.2 2.8 3.2 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 Med5 PF08689.5 CCC69657.1 - 5.5e-248 825.4 45.3 6.2e-248 825.2 31.4 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 SNF2_N PF00176.18 CCC69658.1 - 2.6e-71 239.8 3.6 2.6e-71 239.8 2.5 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 CCC69658.1 - 9.2e-51 171.5 23.8 9.2e-51 171.5 16.5 3.6 3 1 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 CCC69658.1 - 1.3e-13 50.5 0.0 4.1e-13 49.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chorismate_synt PF01264.16 CCC69659.1 - 4.6e-133 442.9 0.0 5.3e-133 442.7 0.0 1.0 1 0 0 1 1 1 1 Chorismate synthase Ribosomal_L6 PF00347.18 CCC69660.1 - 4.9e-28 97.4 12.0 3.5e-14 53.0 3.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 YbbR PF07949.7 CCC69660.1 - 0.013 15.5 1.7 2.2 8.4 0.4 3.1 1 1 2 3 3 3 0 YbbR-like protein RNase_PH PF01138.16 CCC69661.1 - 8.7e-12 45.4 0.1 1.3e-11 44.9 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 EMP24_GP25L PF01105.19 CCC69662.1 - 1.1e-07 31.8 0.1 1.6e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD RINT1_TIP1 PF04437.8 CCC69663.1 - 6.4e-101 338.3 24.6 6.4e-101 338.3 17.0 2.3 2 1 1 3 3 3 1 RINT-1 / TIP-1 family DUF676 PF05057.9 CCC69664.1 - 3e-57 193.4 0.0 5.2e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) LCAT PF02450.10 CCC69664.1 - 0.0015 17.5 0.6 0.0041 16.1 0.0 1.8 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.20 CCC69664.1 - 0.0084 15.7 0.0 0.024 14.2 0.0 1.8 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 CCC69664.1 - 0.016 14.7 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein PP2C PF00481.16 CCC69665.1 - 2.2e-59 200.9 0.1 3.9e-59 200.0 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 CCC69665.1 - 2.6e-42 141.8 77.5 1.8e-06 27.4 1.2 13.2 5 4 6 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCC69665.1 - 3.9e-41 138.6 64.1 2.9e-08 33.3 6.0 10.0 8 1 1 9 9 9 8 Leucine rich repeat Guanylate_cyc PF00211.15 CCC69665.1 - 2.1e-28 98.9 0.0 4.4e-28 97.9 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 CCC69665.1 - 6.5e-14 49.8 71.3 0.64 10.2 0.7 19.0 16 3 3 19 19 19 5 Leucine Rich Repeat RA PF00788.18 CCC69665.1 - 1.9e-07 31.4 0.0 5.7e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain LRR_7 PF13504.1 CCC69665.1 - 1.3e-05 24.6 52.9 0.74 10.2 0.1 16.8 19 0 0 19 19 19 2 Leucine rich repeat LRR_6 PF13516.1 CCC69665.1 - 0.00022 20.9 59.9 2.4 8.4 0.2 15.6 15 1 1 16 16 16 3 Leucine Rich repeat PP2C_2 PF13672.1 CCC69665.1 - 0.0012 18.3 0.9 0.0076 15.6 0.0 2.3 2 0 0 2 2 2 1 Protein phosphatase 2C Ad_cyc_g-alpha PF08509.6 CCC69665.1 - 0.0064 15.7 0.2 0.0064 15.7 0.1 3.3 3 0 0 3 3 3 1 Adenylate cyclase G-alpha binding domain HECT PF00632.20 CCC69666.1 - 9.8e-86 287.7 1.7 1.7e-85 286.9 1.2 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 CCC69666.1 - 0.00096 18.5 0.2 0.0021 17.5 0.1 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif Glyco_transf_22 PF03901.12 CCC69667.1 - 2.2e-108 362.9 35.7 2.6e-108 362.7 24.8 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF228 PF02989.9 CCC69667.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.5 1 0 0 1 1 1 0 Lyme disease proteins of unknown function SPRY PF00622.23 CCC69668.1 - 2e-12 47.2 0.0 4e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 SPRY domain DUF912 PF06024.7 CCC69668.1 - 0.015 15.3 0.4 0.015 15.3 0.3 3.2 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Myc_target_1 PF15179.1 CCC69668.1 - 0.14 11.7 0.9 0.19 11.2 0.1 1.6 2 0 0 2 2 2 0 Myc target protein 1 IncA PF04156.9 CCC69668.1 - 4 6.9 4.1 30 4.1 0.0 2.9 3 0 0 3 3 3 0 IncA protein Aldedh PF00171.17 CCC69669.1 - 6.8e-161 535.6 0.0 7.8e-161 535.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Saccharop_dh PF03435.13 CCC69669.1 - 0.074 12.0 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Zn_clus PF00172.13 CCC69670.1 - 3.4e-07 30.0 8.6 7.5e-07 28.9 6.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DNA_mis_repair PF01119.14 CCC69671.1 - 1.1e-30 105.5 2.9 1.6e-30 104.9 0.7 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 CCC69671.1 - 1.6e-14 53.7 0.3 4.9e-14 52.1 0.2 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCC69671.1 - 8.2e-11 41.6 0.1 2.5e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Mito_carr PF00153.22 CCC69672.1 - 3.8e-64 212.4 2.3 6.7e-22 77.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein LNS2 PF08235.8 CCC69673.1 - 5.8e-68 227.4 0.0 7.3e-54 181.5 0.0 2.3 2 0 0 2 2 2 2 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 CCC69673.1 - 6.9e-45 151.2 0.0 1.9e-44 149.8 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region Hydrolase_4 PF12146.3 CCC69673.1 - 0.086 12.7 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Vezatin PF12632.2 CCC69675.1 - 1.6e-21 76.5 11.5 7.1e-21 74.4 8.0 2.0 1 1 0 1 1 1 1 Mysoin-binding motif of peroxisomes E1-E2_ATPase PF00122.15 CCC69676.1 - 4.5e-22 78.2 0.3 1.5e-20 73.2 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 CCC69676.1 - 3.4e-15 57.0 0.4 6.9e-12 46.2 0.3 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 CCC69676.1 - 3.1e-13 50.3 1.1 9.9e-12 45.4 0.7 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCC69676.1 - 4.8e-12 45.6 0.0 1.9e-11 43.7 0.0 2.1 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCC69676.1 - 0.00082 19.0 1.5 0.0054 16.3 0.2 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DnaJ PF00226.26 CCC69677.1 - 4.6e-26 90.3 1.8 7.1e-26 89.7 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain DUF633 PF04816.7 CCC69677.1 - 0.011 15.0 0.5 0.016 14.5 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF633) ATG16 PF08614.6 CCC69679.1 - 2e-21 76.7 15.4 1.6e-19 70.5 8.8 2.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) TMF_TATA_bd PF12325.3 CCC69679.1 - 1.6e-05 24.6 8.1 3.3e-05 23.6 5.6 1.6 1 1 0 1 1 1 1 TATA element modulatory factor 1 TATA binding Mitofilin PF09731.4 CCC69679.1 - 0.002 16.8 8.4 0.0023 16.6 5.8 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DUF724 PF05266.9 CCC69679.1 - 0.0074 15.9 2.7 0.0095 15.5 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Fib_alpha PF08702.5 CCC69679.1 - 0.0084 16.2 1.8 0.0084 16.2 1.2 1.8 1 1 0 2 2 2 1 Fibrinogen alpha/beta chain family Syntaxin-6_N PF09177.6 CCC69679.1 - 0.011 16.0 2.8 0.013 15.8 0.7 1.8 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Spectrin PF00435.16 CCC69679.1 - 0.013 15.7 5.5 0.021 15.0 3.8 1.4 1 1 0 1 1 1 0 Spectrin repeat GAS PF13851.1 CCC69679.1 - 0.014 14.5 11.2 0.026 13.6 7.7 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding IQ-like PF15157.1 CCC69679.1 - 0.017 15.2 2.6 0.03 14.5 1.8 1.3 1 0 0 1 1 1 0 IQ-like Atg14 PF10186.4 CCC69679.1 - 0.018 13.9 4.0 0.019 13.8 2.8 1.0 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4201 PF13870.1 CCC69679.1 - 0.024 14.0 8.7 0.044 13.2 6.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) IncA PF04156.9 CCC69679.1 - 0.041 13.4 6.9 0.046 13.3 4.8 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 CCC69679.1 - 0.051 12.6 6.7 0.055 12.5 4.7 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 CCC69679.1 - 0.11 10.8 5.4 0.13 10.6 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) TMF_DNA_bd PF12329.3 CCC69679.1 - 0.11 12.2 13.8 0.22 11.3 9.5 1.5 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding RUN PF02759.14 CCC69679.1 - 0.13 12.0 0.2 0.16 11.6 0.2 1.3 1 0 0 1 1 1 0 RUN domain Phage_lysis PF03245.8 CCC69679.1 - 0.29 11.1 2.9 0.28 11.1 0.7 1.7 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Cep57_MT_bd PF06657.8 CCC69679.1 - 0.33 10.9 5.0 4.8 7.2 0.2 2.8 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 SYCE1 PF15233.1 CCC69679.1 - 0.46 10.4 8.6 0.72 9.7 6.0 1.3 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 DUF4200 PF13863.1 CCC69679.1 - 0.84 9.5 8.8 0.68 9.8 4.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Nsp1_C PF05064.8 CCC69679.1 - 0.9 9.2 9.8 0.48 10.0 1.8 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region TBPIP PF07106.8 CCC69679.1 - 1.1 8.7 12.3 2.1 7.8 2.0 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TPD52 PF04201.10 CCC69679.1 - 1.1 8.9 9.4 2 8.0 3.4 2.1 1 1 1 2 2 2 0 Tumour protein D52 family Kinesin-relat_1 PF12711.2 CCC69679.1 - 1.3 9.5 10.0 1.6 9.1 3.9 2.6 1 1 1 2 2 2 0 Kinesin motor Ly49 PF08391.5 CCC69679.1 - 1.4 9.0 5.0 2.2 8.4 3.5 1.4 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region DUF972 PF06156.8 CCC69679.1 - 2.5 8.5 8.5 4.8 7.5 5.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF641 PF04859.7 CCC69679.1 - 2.6 7.7 8.3 1.2 8.9 3.1 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Spc42p PF11544.3 CCC69679.1 - 2.8 7.9 10.1 6.3 6.8 5.9 2.4 1 1 0 1 1 1 0 Spindle pole body component Spc42p DUF1664 PF07889.7 CCC69679.1 - 3 7.6 7.8 2.5 7.9 3.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HR1 PF02185.11 CCC69679.1 - 4.8 6.9 10.5 4.5 7.0 2.8 2.3 1 1 0 2 2 2 0 Hr1 repeat Ribosomal_S8 PF00410.14 CCC69680.1 - 2.3e-25 88.9 0.0 3.4e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S8 Ehbp PF10622.4 CCC69681.1 - 0.11 12.4 0.2 0.29 11.0 0.0 1.8 2 0 0 2 2 2 0 Energy-converting hydrogenase B subunit P (EhbP) PNK3P PF08645.6 CCC69682.1 - 5.5e-44 149.4 0.8 6.5e-44 149.1 0.6 1.0 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase MFS_1 PF07690.11 CCC69683.1 - 1.1e-11 44.0 16.2 1.1e-11 44.0 11.2 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Nodulin-like PF06813.8 CCC69683.1 - 2.2e-08 33.7 12.8 2.6e-08 33.4 5.3 2.4 2 0 0 2 2 2 1 Nodulin-like TMEM138 PF14935.1 CCC69683.1 - 0.27 11.5 3.2 2.4 8.5 0.2 2.7 2 0 0 2 2 2 0 Transmembrane protein 138 Nup35_RRM PF05172.8 CCC69685.1 - 1.9e-35 120.6 0.0 5.7e-35 119.1 0.0 1.8 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 CCC69685.1 - 1.8e-05 24.4 0.0 6.3e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif ADH_zinc_N_2 PF13602.1 CCC69686.1 - 3.1e-12 47.4 0.0 6.5e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCC69686.1 - 4.4e-10 39.2 0.0 9e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCC69686.1 - 2.7e-06 27.0 0.0 1.5e-05 24.6 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 CCC69686.1 - 0.046 14.0 0.0 0.091 13.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 CCC69688.1 - 1.9e-12 48.1 0.0 4e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCC69688.1 - 1e-05 25.0 0.0 1.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCC69688.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain NAGLU PF05089.7 CCC69688.1 - 0.13 10.9 0.1 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain ADH_zinc_N_2 PF13602.1 CCC69689.1 - 6e-11 43.3 0.0 2.2e-10 41.5 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 CCC69689.1 - 8.2e-08 31.8 0.0 1.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCC69689.1 - 3.2e-06 26.8 0.0 0.00013 21.6 0.0 2.3 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 CCC69689.1 - 0.017 15.4 0.0 0.04 14.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Baculo_gp41 PF04700.7 CCC69689.1 - 0.049 13.0 0.1 0.098 12.0 0.0 1.5 1 0 0 1 1 1 0 Structural glycoprotein p40/gp41 conserved region Peptidase_S24 PF00717.18 CCC69690.1 - 1.8e-07 30.6 0.0 8.8e-07 28.4 0.0 2.1 2 1 1 3 3 3 1 Peptidase S24-like Peptidase_S26 PF10502.4 CCC69690.1 - 0.0046 16.4 0.0 0.027 13.9 0.0 2.0 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Ribophorin_II PF05817.9 CCC69691.1 - 2e-07 29.6 0.5 2.4e-07 29.3 0.4 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II DUF1700 PF08006.6 CCC69691.1 - 0.25 10.6 4.9 0.56 9.4 3.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Pex24p PF06398.6 CCC69692.1 - 0.0072 15.1 0.3 0.0079 15.0 0.2 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin CAAD PF14159.1 CCC69692.1 - 0.12 12.0 2.4 0.2 11.3 1.7 1.4 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase FANCI_HD2 PF14680.1 CCC69693.1 - 0.021 13.9 0.2 0.026 13.6 0.1 1.2 1 0 0 1 1 1 0 FANCI helical domain 2 OHCU_decarbox PF09349.5 CCC69693.1 - 0.038 14.2 0.0 0.052 13.8 0.0 1.1 1 0 0 1 1 1 0 OHCU decarboxylase WD40 PF00400.27 CCC69694.1 - 5.2e-31 105.3 3.1 5.4e-08 32.4 0.1 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 CCC69694.1 - 3.6e-06 26.8 0.1 0.05 13.3 0.1 3.5 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 CCC69694.1 - 0.0017 17.2 0.2 0.88 8.2 0.0 2.2 2 0 0 2 2 2 2 Nup133 N terminal like 4F5 PF04419.9 CCC69695.1 - 1.1e-07 32.4 9.0 1.1e-07 32.4 6.2 2.2 2 0 0 2 2 2 1 4F5 protein family PP28 PF10252.4 CCC69695.1 - 0.016 15.2 2.3 0.016 15.2 1.6 2.2 1 1 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 DUF1843 PF08898.5 CCC69695.1 - 0.3 11.1 9.8 0.7 9.9 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Pyr_redox_2 PF07992.9 CCC69696.1 - 2.7e-29 102.5 0.0 1.6e-19 70.6 0.0 4.1 3 1 1 4 4 4 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCC69696.1 - 1.4e-11 44.6 0.0 1.8e-10 41.0 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCC69696.1 - 2.7e-07 30.8 0.0 0.00092 19.3 0.0 3.4 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCC69696.1 - 0.0034 17.1 0.0 0.82 9.4 0.0 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding Tropomyosin PF00261.15 CCC69696.1 - 0.025 13.6 1.0 0.052 12.6 0.7 1.5 1 0 0 1 1 1 0 Tropomyosin CR6_interact PF10147.4 CCC69696.1 - 0.072 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF3373 PF11853.3 CCC69697.1 - 0.013 14.1 1.7 0.017 13.7 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) 7kD_DNA_binding PF02294.13 CCC69697.1 - 0.053 13.2 0.4 0.13 11.9 0.1 1.8 2 0 0 2 2 2 0 7kD DNA-binding domain WEMBL PF05701.6 CCC69697.1 - 0.091 11.2 7.2 0.49 8.8 2.8 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Spc7 PF08317.6 CCC69697.1 - 0.14 10.7 9.2 2.3 6.7 0.5 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 CCC69697.1 - 0.19 10.8 2.2 0.4 9.8 1.2 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein FlxA PF14282.1 CCC69697.1 - 2.1 8.3 7.8 0.12 12.3 0.7 2.3 1 1 1 2 2 2 0 FlxA-like protein FliJ PF02050.11 CCC69697.1 - 2.3 8.2 11.6 6.6 6.7 5.5 2.4 1 1 2 3 3 3 0 Flagellar FliJ protein DUF2051 PF09738.4 CCC69697.1 - 2.6 7.2 12.2 4.4 6.5 8.3 1.5 1 1 0 1 1 1 0 Double stranded RNA binding protein (DUF2051) TMF_DNA_bd PF12329.3 CCC69697.1 - 5.8 6.7 10.3 28 4.6 0.0 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Ribosomal_S9 PF00380.14 CCC69698.1 - 6.7e-39 132.8 0.2 7.6e-39 132.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Glyco_trans_1_3 PF13528.1 CCC69698.1 - 0.032 13.4 0.0 0.04 13.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferase family 1 Ribosomal_L13e PF01294.13 CCC69699.1 - 3.5e-72 241.6 4.7 4.6e-72 241.2 3.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e 4HBT_3 PF13622.1 CCC69699.1 - 0.052 13.2 0.1 0.068 12.9 0.1 1.3 1 0 0 1 1 1 0 Thioesterase-like superfamily Ribosomal_60s PF00428.14 CCC69700.1 - 1.1e-20 73.7 8.7 1.4e-20 73.4 6.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein zf-C3HC4_2 PF13923.1 CCC69701.1 - 1.6 8.8 8.4 9.7 6.3 5.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Dimer_Tnp_hAT PF05699.9 CCC69702.1 - 6e-06 25.7 1.2 1.6e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 CCC69702.1 - 0.0014 18.3 5.7 0.0014 18.3 3.9 2.2 2 0 0 2 2 2 1 BED zinc finger ADH_N PF08240.7 CCC69703.1 - 7.1e-28 96.5 5.6 1.5e-27 95.5 3.8 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCC69703.1 - 1.1e-14 54.0 0.0 1.7e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 CCC69703.1 - 1.1e-05 24.6 0.4 1.9e-05 23.8 0.3 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 CCC69703.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pkinase PF00069.20 CCC69704.1 - 1.7e-60 204.3 0.0 2.6e-60 203.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69704.1 - 2.2e-21 76.0 0.0 4e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.15 CCC69704.1 - 8.8e-05 22.1 0.2 0.00016 21.3 0.1 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 CCC69704.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Arf PF00025.16 CCC69705.1 - 1.6e-42 144.7 0.1 1.9e-42 144.4 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 CCC69705.1 - 1.5e-13 50.2 3.3 1e-08 34.3 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 CCC69705.1 - 3.7e-10 39.4 0.0 4.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 CCC69705.1 - 3.6e-09 36.5 0.0 5.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCC69705.1 - 2.4e-08 33.4 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCC69705.1 - 5.7e-08 33.2 0.0 7.8e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 CCC69705.1 - 1.2e-05 24.6 0.0 1.5e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CCC69705.1 - 0.0003 20.2 0.0 0.046 13.1 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CCC69705.1 - 0.00083 18.6 0.3 0.015 14.5 0.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_29 PF13555.1 CCC69705.1 - 0.0045 16.4 0.2 0.29 10.6 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 CCC69705.1 - 0.024 14.1 0.0 4.4 6.7 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 CCC69705.1 - 0.038 13.1 0.0 0.096 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MobB PF03205.9 CCC69705.1 - 0.057 13.1 0.0 0.14 11.8 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CCC69705.1 - 0.079 12.9 0.0 0.21 11.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Arch_ATPase PF01637.13 CCC69705.1 - 0.091 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 Archaeal ATPase DAP3 PF10236.4 CCC69705.1 - 0.16 10.8 0.2 0.21 10.4 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DRMBL PF07522.9 CCC69706.1 - 3e-26 91.6 0.2 1e-25 89.8 0.0 2.1 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 CCC69706.1 - 2.2e-07 30.5 0.1 6.1e-07 29.1 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BNR_assoc_N PF14873.1 CCC69706.1 - 0.15 11.8 2.1 0.36 10.5 1.5 1.7 1 1 0 1 1 1 0 N-terminal domain of BNR-repeat neuraminidase GATA PF00320.22 CCC69707.1 - 1.5e-15 56.2 4.1 2.7e-15 55.3 2.8 1.4 1 0 0 1 1 1 1 GATA zinc finger Erv26 PF04148.8 CCC69708.1 - 1.4e-84 282.6 3.8 1.6e-84 282.5 2.7 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Oxidored_FMN PF00724.15 CCC69709.1 - 2.3e-131 437.8 0.0 2.7e-131 437.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.13 CCC69710.1 - 1e-31 109.8 0.2 1.7e-31 109.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC69710.1 - 3.2e-07 30.1 12.3 5.2e-07 29.4 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.14 CCC69711.1 - 1.2e-41 142.5 0.2 4.9e-33 114.1 0.1 2.0 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 CCC69711.1 - 4.3e-20 72.6 0.0 1.5e-19 70.9 0.0 1.8 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCC69711.1 - 7.3e-16 58.3 0.0 7.5e-14 51.7 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 CCC69711.1 - 8.6e-12 45.3 0.0 1.4e-11 44.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 CCC69711.1 - 2.1e-10 40.0 0.7 6.9e-09 35.0 0.0 2.6 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 CCC69711.1 - 1.5e-07 31.3 0.0 4e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCC69711.1 - 3.4e-07 29.5 0.0 0.019 13.8 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 CCC69711.1 - 8e-06 26.1 0.3 2.9 8.3 0.0 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCC69711.1 - 2.3e-05 23.6 0.1 0.0049 15.9 0.0 2.4 2 0 0 2 2 2 2 Thi4 family NAD_Gly3P_dh_N PF01210.18 CCC69711.1 - 0.008 15.9 0.0 2.3 7.9 0.1 2.4 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 CCC69711.1 - 0.013 13.9 0.1 0.37 9.1 0.1 2.6 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_7 PF13241.1 CCC69711.1 - 0.074 13.3 0.0 4.4 7.6 0.0 2.6 2 1 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.7 CCC69711.1 - 0.089 12.1 0.0 3.8 6.8 0.0 2.3 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain FAD_binding_3 PF01494.14 CCC69711.1 - 0.15 11.0 0.1 2.6 7.0 0.0 2.5 3 0 0 3 3 3 0 FAD binding domain Ctr PF04145.10 CCC69712.1 - 1.2e-28 99.9 16.6 3.1e-26 92.1 11.5 2.1 1 1 0 1 1 1 1 Ctr copper transporter family Bestrophin PF01062.16 CCC69712.1 - 0.017 14.0 6.5 0.097 11.5 0.1 2.1 1 1 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel DUF3329 PF11808.3 CCC69712.1 - 9.9 6.3 8.5 5 7.2 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3329) Enolase_C PF00113.17 CCC69713.1 - 2.2e-151 502.9 0.0 3e-151 502.4 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 CCC69713.1 - 7.2e-57 190.9 0.7 1.2e-56 190.2 0.5 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 CCC69713.1 - 0.0034 17.3 0.2 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.6 CCC69713.1 - 0.024 13.5 0.7 0.1 11.5 0.1 2.0 2 0 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 CCC69713.1 - 0.073 13.6 0.0 0.29 11.6 0.0 2.1 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Spc97_Spc98 PF04130.8 CCC69714.1 - 8.9e-75 252.0 25.9 1.1e-74 251.7 18.0 1.1 1 0 0 1 1 1 1 Spc97 / Spc98 family Proteasome PF00227.21 CCC69715.1 - 1.6e-53 180.8 0.0 2.2e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCC69715.1 - 2e-13 49.3 0.1 4e-13 48.4 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ThiF PF00899.16 CCC69716.1 - 2e-32 111.8 0.0 3.9e-32 110.9 0.0 1.5 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 CCC69716.1 - 0.0006 19.9 0.0 0.0075 16.3 0.0 2.6 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 CCC69716.1 - 0.022 13.8 0.0 1.7 7.7 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain VWA PF00092.23 CCC69716.1 - 0.04 13.6 0.1 0.16 11.6 0.1 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain NMD3 PF04981.8 CCC69717.1 - 7.1e-77 257.7 1.4 1.3e-76 256.8 1.0 1.4 1 0 0 1 1 1 1 NMD3 family Phage_int_SAM_4 PF13495.1 CCC69717.1 - 0.52 10.6 4.1 2.2 8.6 0.8 2.6 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DZR PF12773.2 CCC69717.1 - 0.78 9.6 7.9 3.9 7.3 3.8 2.7 2 1 0 2 2 2 0 Double zinc ribbon NinF PF05810.7 CCC69717.1 - 1.1 9.1 5.4 7.4 6.4 0.5 3.2 3 0 0 3 3 3 0 NinF protein HypA PF01155.14 CCC69717.1 - 1.6 8.4 6.1 21 4.8 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FYVE PF01363.16 CCC69717.1 - 1.8 8.4 7.1 3.3 7.6 2.7 2.4 2 0 0 2 2 2 0 FYVE zinc finger zinc_ribbon_6 PF14599.1 CCC69717.1 - 4.9 7.0 9.9 0.63 9.8 0.1 3.4 2 1 0 2 2 2 0 Zinc-ribbon GTP1_OBG PF01018.17 CCC69718.1 - 1e-32 112.9 1.6 1.9e-22 79.6 0.8 2.2 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 CCC69718.1 - 5.5e-19 68.2 0.0 1.2e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCC69718.1 - 3e-13 49.3 0.0 4.5e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Arf PF00025.16 CCC69718.1 - 0.00018 20.7 0.0 0.00045 19.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 CCC69718.1 - 0.0008 19.8 0.0 0.0018 18.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CCC69718.1 - 0.0011 18.3 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 Ras family GTP_EFTU PF00009.22 CCC69718.1 - 0.0036 16.7 0.0 0.43 9.9 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CCC69718.1 - 0.022 13.9 0.0 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ArgK PF03308.11 CCC69718.1 - 0.14 10.8 0.1 1.1 8.0 0.0 2.0 2 0 0 2 2 2 0 ArgK protein THP2 PF09432.5 CCC69719.1 - 3.3e-48 162.8 2.6 3.3e-48 162.8 1.8 1.7 2 1 0 2 2 2 1 Tho complex subunit THP2 LUC7 PF03194.10 CCC69719.1 - 0.015 14.8 1.4 0.015 14.8 1.0 2.2 2 1 0 2 2 2 0 LUC7 N_terminus Mating_N PF12731.2 CCC69719.1 - 0.12 12.2 2.6 1.6 8.6 0.2 2.7 1 1 1 2 2 2 0 Mating-type protein beta 1 Hist_deacetyl PF00850.14 CCC69719.1 - 0.21 10.8 1.7 0.5 9.5 1.2 1.9 1 1 0 1 1 1 0 Histone deacetylase domain AATF-Che1 PF13339.1 CCC69719.1 - 0.45 10.6 10.9 1.3 9.1 3.2 2.7 2 2 0 2 2 2 0 Apoptosis antagonizing transcription factor DUF2408 PF10303.4 CCC69719.1 - 2.3 8.3 7.9 11 6.0 0.2 3.2 2 2 0 2 2 2 0 Protein of unknown function (DUF2408) DUF342 PF03961.8 CCC69719.1 - 9.5 4.5 10.2 1 7.6 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF342) APC8 PF04049.8 CCC69720.1 - 1.5e-39 134.9 2.4 3.8e-39 133.6 1.7 1.6 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.1 CCC69720.1 - 1.6e-21 75.7 14.9 1e-07 31.4 0.1 5.7 4 1 1 5 5 5 3 TPR repeat TPR_1 PF00515.23 CCC69720.1 - 3.3e-21 73.9 22.1 3.8e-06 26.2 0.0 8.0 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCC69720.1 - 4.3e-18 63.6 20.6 0.00053 19.5 0.0 8.7 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.12 CCC69720.1 - 5.9e-17 60.1 19.5 2.6e-05 23.7 0.0 8.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCC69720.1 - 2.8e-12 46.4 19.5 2.8e-06 27.1 0.2 6.0 3 1 4 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCC69720.1 - 3.3e-12 45.8 0.0 0.18 12.5 0.0 6.5 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCC69720.1 - 1.2e-09 38.5 0.5 0.0023 18.5 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCC69720.1 - 4.5e-09 35.4 8.9 0.044 13.5 0.0 6.8 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCC69720.1 - 5.7e-07 29.5 16.1 0.54 10.8 0.0 9.0 10 0 0 10 10 9 2 Tetratricopeptide repeat Apc3 PF12895.2 CCC69720.1 - 7.1e-07 29.2 20.8 0.051 13.7 0.7 6.3 2 1 5 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CCC69720.1 - 3.2e-06 26.8 12.5 0.52 10.6 0.0 6.2 7 0 0 7 7 5 3 Tetratricopeptide repeat RPN7 PF10602.4 CCC69720.1 - 1.3e-05 24.6 0.6 1.3e-05 24.6 0.4 2.1 2 1 1 3 3 2 1 26S proteasome subunit RPN7 TPR_9 PF13371.1 CCC69720.1 - 2.2e-05 24.2 0.1 0.031 14.1 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCC69720.1 - 5.3e-05 22.4 1.1 0.1 11.6 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat ChAPs PF09295.5 CCC69720.1 - 7.9e-05 21.5 1.5 0.026 13.2 0.1 2.3 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_19 PF14559.1 CCC69720.1 - 0.0059 16.9 3.9 0.66 10.3 0.2 4.7 5 1 1 6 6 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 CCC69720.1 - 0.011 15.5 1.2 1.1 9.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 CCC69720.1 - 0.037 13.8 0.1 5.3 7.0 0.0 3.8 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain NSF PF02071.15 CCC69720.1 - 0.044 14.2 0.4 68 4.7 0.0 4.9 4 0 0 4 4 3 0 Aromatic-di-Alanine (AdAR) repeat BTAD PF03704.12 CCC69720.1 - 0.076 13.3 0.4 0.24 11.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial transcriptional activator domain PROCN PF08083.6 CCC69721.1 - 9.4e-221 732.4 9.9 1.5e-220 731.8 6.9 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 CCC69721.1 - 3e-122 406.2 1.8 6.4e-122 405.2 1.2 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 CCC69721.1 - 7.6e-88 291.9 0.6 1.6e-87 290.8 0.4 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 CCC69721.1 - 7.4e-76 252.9 3.6 1.7e-75 251.7 2.5 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 CCC69721.1 - 1.3e-63 212.5 0.1 1.2e-62 209.5 0.0 2.3 1 1 1 2 2 2 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 CCC69721.1 - 1.2e-45 154.2 0.1 2.9e-45 153.0 0.1 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.4 CCC69721.1 - 3.1e-45 151.9 0.2 1.1e-44 150.2 0.2 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 CCC69721.1 - 6.9e-05 22.5 0.0 0.00036 20.2 0.0 2.3 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FAM60A PF15396.1 CCC69722.1 - 0.02 14.6 1.3 0.02 14.6 0.9 4.7 4 1 0 4 4 4 0 Protein Family FAM60A Dna2 PF08696.6 CCC69723.1 - 3.5e-64 215.9 0.4 9.7e-64 214.5 0.1 2.0 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 CCC69723.1 - 5.3e-49 166.3 1.0 1.1e-48 165.2 0.7 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCC69723.1 - 2.7e-37 128.5 5.6 2.3e-20 73.2 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 CCC69723.1 - 1e-11 44.7 0.0 2.6e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 CCC69723.1 - 7.5e-09 35.3 0.0 2e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 CCC69723.1 - 3.4e-08 33.3 1.0 0.06 12.8 0.0 4.5 3 1 1 4 4 4 3 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 CCC69723.1 - 8.6e-08 31.8 0.0 1.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain Cas_Cas4 PF01930.12 CCC69723.1 - 2.5e-07 30.7 0.0 7.8e-07 29.1 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function DUF83 UvrD-helicase PF00580.16 CCC69723.1 - 4.3e-05 22.9 6.0 6e-05 22.4 0.0 2.8 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain Helicase_RecD PF05127.9 CCC69723.1 - 0.00065 19.3 0.0 0.0018 17.9 0.0 1.8 1 0 0 1 1 1 1 Helicase SRP54 PF00448.17 CCC69723.1 - 0.001 18.5 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain MobB PF03205.9 CCC69723.1 - 0.0018 17.9 0.1 0.0049 16.5 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CCC69723.1 - 0.0028 17.6 0.0 0.0084 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 CCC69723.1 - 0.01 14.7 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein CbiA PF01656.18 CCC69723.1 - 0.016 14.5 0.1 0.081 12.3 0.0 2.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 CCC69723.1 - 0.017 14.6 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 CCC69723.1 - 0.025 14.2 0.1 0.1 12.3 0.1 2.0 1 0 0 1 1 1 0 NTPase Arch_ATPase PF01637.13 CCC69723.1 - 0.028 14.1 0.0 0.028 14.1 0.0 3.0 4 0 0 4 4 3 0 Archaeal ATPase AAA_18 PF13238.1 CCC69723.1 - 0.044 14.0 0.0 0.044 14.0 0.0 3.0 3 1 0 3 3 3 0 AAA domain UvrD_C_2 PF13538.1 CCC69723.1 - 0.055 13.6 0.0 0.18 11.9 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Mg_chelatase PF01078.16 CCC69723.1 - 0.067 12.3 0.0 0.13 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CCC69723.1 - 0.13 12.1 0.0 0.38 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain Glucosamine_iso PF01182.15 CCC69724.1 - 7.3e-54 182.5 0.0 1.5e-53 181.5 0.0 1.5 2 0 0 2 2 2 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DDE_1 PF03184.14 CCC69725.1 - 2.9e-06 26.5 0.0 7.9e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 DDE superfamily endonuclease NUMOD1 PF07453.8 CCC69725.1 - 0.00028 20.5 0.1 0.28 11.1 0.0 3.8 4 0 0 4 4 4 1 NUMOD1 domain HTH_23 PF13384.1 CCC69725.1 - 0.016 14.8 0.2 15 5.3 0.0 3.4 3 0 0 3 3 3 0 Homeodomain-like domain HTH_28 PF13518.1 CCC69725.1 - 0.036 14.0 0.0 4.6 7.3 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_10 PF04967.7 CCC69725.1 - 0.065 12.8 0.0 18 5.0 0.0 2.7 2 0 0 2 2 2 0 HTH DNA binding domain HTH_psq PF05225.11 CCC69725.1 - 0.13 11.8 0.1 15 5.2 0.0 2.6 2 0 0 2 2 2 0 helix-turn-helix, Psq domain MPC PF03650.8 CCC69726.1 - 9.5e-49 164.3 0.1 1.1e-48 164.1 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ANTH PF07651.11 CCC69727.1 - 4.1e-65 219.2 0.6 4.1e-65 219.2 0.4 2.0 2 0 0 2 2 2 1 ANTH domain ENTH PF01417.15 CCC69727.1 - 3.6e-06 26.8 0.0 1.1e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 ENTH domain zf-C4H2 PF10146.4 CCC69728.1 - 6.1 6.7 8.6 2.1 8.3 3.7 1.8 2 0 0 2 2 2 0 Zinc finger-containing protein HrcA PF01628.16 CCC69729.1 - 0.019 14.5 0.2 0.019 14.5 0.1 1.7 2 1 0 2 2 2 0 HrcA protein C terminal domain IncA PF04156.9 CCC69729.1 - 3.2 7.2 6.7 0.33 10.5 0.4 2.1 2 0 0 2 2 2 0 IncA protein PTCB-BRCT PF12738.2 CCC69732.1 - 2.8e-19 68.7 1.1 2.5e-13 49.6 0.0 3.7 4 0 0 4 4 4 2 twin BRCT domain BRCT PF00533.21 CCC69732.1 - 1.4e-16 60.3 15.3 3.6e-06 27.0 0.0 5.7 6 0 0 6 6 6 3 BRCA1 C Terminus (BRCT) domain TMV_coat PF00721.16 CCC69733.1 - 0.052 13.4 0.0 0.078 12.9 0.0 1.3 1 0 0 1 1 1 0 Virus coat protein (TMV like) Spo12 PF05032.7 CCC69734.1 - 6.4e-16 57.6 4.3 6.4e-16 57.6 3.0 2.0 2 0 0 2 2 2 1 Spo12 family Pex24p PF06398.6 CCC69736.1 - 3.7e-66 223.3 0.9 5.4e-66 222.8 0.6 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin SKG6 PF08693.5 CCC69737.1 - 8.2e-12 44.2 3.7 1.8e-11 43.1 2.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Shisa PF13908.1 CCC69737.1 - 0.00023 21.3 3.9 0.00023 21.3 2.7 4.4 3 1 1 5 5 5 1 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 CCC69737.1 - 0.00088 18.9 0.9 0.012 15.3 0.0 2.9 2 0 0 2 2 2 1 TMEM154 protein family DUF4448 PF14610.1 CCC69737.1 - 0.0017 17.8 0.0 0.0045 16.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF912 PF06024.7 CCC69737.1 - 0.67 10.0 0.0 0.67 10.0 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Ribosomal_S4 PF00163.14 CCC69738.1 - 1.9e-26 92.2 1.4 2.9e-26 91.6 1.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 CCC69738.1 - 7.7e-13 47.6 0.0 9.8e-12 44.1 0.0 2.2 2 0 0 2 2 2 1 S4 domain Herpes_LAMP2 PF06126.6 CCC69738.1 - 0.0056 15.1 0.1 0.0068 14.8 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus Latent membrane protein 2 Ribosomal_L6 PF00347.18 CCC69739.1 - 5.4e-22 78.0 0.2 3.8e-10 40.1 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L6 CRM1_C PF08767.6 CCC69740.1 - 3.2e-71 239.8 15.3 3.2e-71 239.8 10.6 2.6 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.7 CCC69740.1 - 4.3e-30 104.5 6.7 4.3e-30 104.5 4.7 3.9 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 CCC69740.1 - 5e-12 45.5 0.0 2.9e-11 43.1 0.0 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain AA_permease_2 PF13520.1 CCC69741.1 - 1.6e-64 218.0 43.2 2e-64 217.7 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCC69741.1 - 4.5e-21 74.7 29.4 4.5e-21 74.7 20.4 1.7 1 1 0 2 2 2 1 Amino acid permease DPM2 PF07297.7 CCC69743.1 - 1.2e-08 35.0 8.9 1.4e-08 34.9 6.2 1.1 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DctQ PF04290.7 CCC69743.1 - 0.89 9.3 6.4 1 9.0 4.4 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Ribosomal_S2 PF00318.15 CCC69744.1 - 4.3e-41 140.4 0.0 5.6e-21 74.7 0.0 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 Ferric_reduct PF01794.14 CCC69745.1 - 9.6e-17 61.2 11.0 9.6e-17 61.2 7.6 1.7 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 CCC69745.1 - 0.0023 17.8 0.0 0.018 14.9 0.0 2.3 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 CCC69745.1 - 0.0081 16.0 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Glyco_hydro_16 PF00722.16 CCC69746.1 - 1.5e-20 73.2 5.2 2.9e-20 72.3 3.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.1 CCC69746.1 - 0.0003 21.0 3.1 0.0003 21.0 2.1 2.1 1 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Macoilin PF09726.4 CCC69746.1 - 3.8 5.6 9.3 5.3 5.1 6.4 1.1 1 0 0 1 1 1 0 Transmembrane protein TPP_enzyme_N PF02776.13 CCC69747.1 - 4.6e-34 117.3 0.0 7e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCC69747.1 - 6.6e-34 116.6 0.0 2.5e-33 114.7 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCC69747.1 - 1.7e-12 47.1 0.0 3e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DUF2893 PF11459.3 CCC69748.1 - 0.0045 16.7 0.4 0.023 14.4 0.1 2.3 2 0 0 2 2 2 1 Protein of unknwon function (DUF2893) HEAT PF02985.17 CCC69748.1 - 0.0064 16.4 1.1 9.2 6.6 0.0 4.8 5 1 1 6 6 6 1 HEAT repeat Vac14_Fab1_bd PF12755.2 CCC69748.1 - 0.048 14.0 0.0 6.6 7.2 0.0 3.1 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region ATG22 PF11700.3 CCC69748.1 - 0.18 10.2 0.0 0.27 9.6 0.0 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like CcdA PF07362.7 CCC69748.1 - 0.2 11.5 11.4 0.043 13.6 2.0 2.9 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Aldolase_II PF00596.16 CCC69749.1 - 9.9e-40 136.1 0.0 1.3e-39 135.7 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain LSM PF01423.17 CCC69750.1 - 9.6e-11 41.0 2.4 1e-10 41.0 0.8 1.7 1 1 0 1 1 1 1 LSM domain Mer2 PF09074.5 CCC69751.1 - 1.5e-25 90.2 18.0 2.3e-25 89.6 12.4 1.2 1 0 0 1 1 1 1 Mer2 CagE_TrbE_VirB PF03135.9 CCC69751.1 - 0.014 15.2 1.7 0.027 14.2 1.2 1.4 1 0 0 1 1 1 0 CagE, TrbE, VirB family, component of type IV transporter system Syntaxin-6_N PF09177.6 CCC69751.1 - 4.8 7.6 7.4 1.6 9.1 1.7 2.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Acyl_CoA_thio PF02551.10 CCC69752.1 - 1.3e-44 151.0 2.4 2.2e-32 111.4 0.4 3.2 2 1 0 2 2 2 2 Acyl-CoA thioesterase 4HBT_3 PF13622.1 CCC69752.1 - 3.6e-27 95.7 0.0 5.6e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Rotamase PF00639.16 CCC69753.1 - 8.1e-29 100.2 0.2 1.2e-28 99.6 0.1 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 CCC69753.1 - 2.5e-21 76.0 0.0 3.8e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 CCC69753.1 - 2.6e-11 44.2 0.3 6e-11 43.0 0.0 1.6 2 0 0 2 2 2 1 PPIC-type PPIASE domain WW PF00397.21 CCC69753.1 - 1e-07 31.6 1.4 1.6e-07 31.0 1.0 1.3 1 0 0 1 1 1 1 WW domain CTP_transf_2 PF01467.21 CCC69754.1 - 5.2e-25 88.3 0.8 8.9e-25 87.5 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase DUF3360 PF11840.3 CCC69754.1 - 0.48 8.6 1.0 0.74 8.0 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) CobT PF06213.7 CCC69754.1 - 7 5.6 23.9 0.045 12.8 4.7 2.3 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT ILVD_EDD PF00920.16 CCC69755.1 - 7.3e-205 681.3 0.6 8.4e-205 681.1 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family Thi4 PF01946.12 CCC69756.1 - 1.3e-95 318.8 0.3 1.6e-95 318.6 0.2 1.0 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 CCC69756.1 - 9.2e-08 31.3 1.2 7.1e-07 28.4 0.3 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCC69756.1 - 3.1e-06 27.0 0.1 9e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 CCC69756.1 - 5.2e-05 22.2 2.7 0.00081 18.3 0.4 2.7 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 CCC69756.1 - 0.0001 22.2 0.1 0.00013 21.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 CCC69756.1 - 0.00011 21.3 0.2 0.00016 20.7 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 CCC69756.1 - 0.00016 21.4 0.0 0.00035 20.3 0.0 1.6 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CCC69756.1 - 0.0068 16.4 0.0 0.0095 16.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCC69756.1 - 0.0069 14.9 0.2 0.0069 14.9 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 CCC69756.1 - 0.0094 15.0 0.2 0.015 14.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 CCC69756.1 - 0.018 13.9 0.1 0.053 12.3 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CCC69756.1 - 0.089 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 CCC69756.1 - 0.11 11.1 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Pribosyltran PF00156.22 CCC69756.1 - 0.25 11.0 1.1 2.4 7.8 0.2 2.8 2 1 0 2 2 2 0 Phosphoribosyl transferase domain DUF3533 PF12051.3 CCC69757.1 - 5.5e-121 403.8 22.0 6.5e-121 403.6 15.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) SUI1 PF01253.17 CCC69758.1 - 3.7e-21 74.7 4.4 7.6e-21 73.7 3.1 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 IF-2 PF11987.3 CCC69758.1 - 0.034 14.0 0.6 0.11 12.4 0.2 1.9 2 0 0 2 2 2 0 Translation-initiation factor 2 DUF3922 PF13059.1 CCC69758.1 - 0.039 14.1 0.7 0.085 13.0 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3992) Cgr1 PF03879.9 CCC69758.1 - 1.4 9.1 11.0 0.39 10.9 4.2 2.1 2 0 0 2 2 2 0 Cgr1 family RNase_PH PF01138.16 CCC69759.1 - 2.7e-27 95.6 0.1 3.8e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCC69759.1 - 5.1e-06 26.3 0.1 1.3e-05 25.0 0.1 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Mannosyl_trans PF05007.8 CCC69760.1 - 3.3e-87 292.4 25.5 4.7e-87 291.9 17.7 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 CCC69760.1 - 5.7e-10 38.6 29.1 3.3e-09 36.0 20.2 1.9 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 CCC69760.1 - 1.5e-09 37.7 3.5 1.5e-09 37.7 2.4 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF2029) PRESAN PF09687.5 CCC69762.1 - 0.13 12.2 2.5 0.2 11.7 0.5 2.2 2 1 0 2 2 2 0 Plasmodium RESA N-terminal SPC12 PF06645.8 CCC69763.1 - 4.7e-24 83.9 0.9 5.8e-24 83.7 0.6 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF443 PF04276.7 CCC69763.1 - 0.013 14.9 0.6 0.014 14.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF443) ATP-sulfurylase PF01747.12 CCC69764.1 - 5.8e-88 293.7 0.0 7.8e-88 293.3 0.0 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 CCC69764.1 - 2.4e-49 166.8 0.0 3.7e-49 166.2 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain Gp_dh_C PF02800.15 CCC69765.1 - 1.1e-74 249.0 0.3 1.9e-74 248.3 0.2 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CCC69765.1 - 7.2e-60 201.3 0.2 1.6e-59 200.1 0.0 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 CCC69765.1 - 0.022 14.6 0.5 0.064 13.1 0.1 2.2 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Memo PF01875.12 CCC69766.1 - 1.8e-92 309.1 0.6 2.1e-92 308.9 0.4 1.0 1 0 0 1 1 1 1 Memo-like protein PTS_EIIA_2 PF00359.17 CCC69766.1 - 0.073 12.7 0.1 2 8.1 0.1 2.4 2 0 0 2 2 2 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 EIF_2_alpha PF07541.7 CCC69767.1 - 9.9e-41 138.0 1.6 1.9e-40 137.1 0.2 1.9 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 CCC69767.1 - 5.8e-14 51.9 1.0 1.6e-13 50.5 0.7 1.7 1 0 0 1 1 1 1 S1 RNA binding domain EXOSC1 PF10447.4 CCC69767.1 - 0.053 13.4 0.2 0.14 12.1 0.1 1.8 1 1 0 1 1 1 0 Exosome component EXOSC1/CSL4 RcsC PF09456.5 CCC69767.1 - 0.13 11.9 0.1 1.8 8.2 0.0 2.3 2 0 0 2 2 2 0 RcsC Alpha-Beta-Loop (ABL) AAA_23 PF13476.1 CCC69767.1 - 0.66 10.2 3.7 1.1 9.4 2.6 1.4 1 0 0 1 1 1 0 AAA domain YbaB_DNA_bd PF02575.11 CCC69767.1 - 0.99 9.3 5.3 10 6.0 0.1 2.9 3 1 0 3 3 3 0 YbaB/EbfC DNA-binding family AA_permease PF00324.16 CCC69768.1 - 3.5e-134 447.7 34.0 4.4e-134 447.4 23.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC69768.1 - 2.9e-39 134.8 35.0 3.5e-39 134.5 24.3 1.0 1 0 0 1 1 1 1 Amino acid permease Glyco_hydro_16 PF00722.16 CCC69770.1 - 1.9e-45 154.4 3.2 1.9e-45 154.4 2.2 2.1 2 1 1 3 3 3 1 Glycosyl hydrolases family 16 Daxx PF03344.10 CCC69770.1 - 2.7 6.3 13.4 3.4 6.0 9.3 1.1 1 0 0 1 1 1 0 Daxx Family RNA_pol_Rpb4 PF03874.11 CCC69771.1 - 5.1e-32 110.3 6.2 7.2e-32 109.8 4.3 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 CMV_1a PF12467.3 CCC69771.1 - 0.0077 16.6 0.2 0.011 16.0 0.2 1.2 1 0 0 1 1 1 1 Cucumber mosaic virus 1a protein family Gag_p10 PF02337.12 CCC69771.1 - 0.07 12.8 0.1 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Retroviral GAG p10 protein LMSTEN PF07988.7 CCC69771.1 - 0.15 11.3 0.3 0.15 11.3 0.2 1.9 2 0 0 2 2 2 0 LMSTEN motif VTC PF09359.5 CCC69772.1 - 3.6e-104 347.7 0.3 5.9e-104 347.0 0.0 1.5 2 0 0 2 2 2 1 VTC domain SPX PF03105.14 CCC69772.1 - 1.9e-23 83.6 11.2 5.3e-11 42.8 0.2 3.8 2 2 1 3 3 3 2 SPX domain DUF202 PF02656.10 CCC69772.1 - 6.2e-08 32.7 6.5 6.2e-08 32.7 3.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Mad3_BUB1_I PF08311.7 CCC69773.1 - 4.9e-36 123.3 1.7 1.1e-35 122.1 1.2 1.6 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_II PF08171.6 CCC69773.1 - 3e-23 81.5 1.0 3.1e-22 78.2 0.1 2.7 2 0 0 2 2 2 1 Mad3/BUB1 homology region 2 Sad1_UNC PF07738.8 CCC69775.1 - 1.3e-05 24.9 2.6 0.053 13.3 0.1 3.0 2 1 1 3 3 3 2 Sad1 / UNC-like C-terminal SH3_1 PF00018.23 CCC69776.1 - 1.7e-10 40.1 0.9 5.3e-10 38.5 0.6 1.9 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCC69776.1 - 1.3e-09 37.3 0.1 3.6e-09 35.9 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 CCC69776.1 - 2.6e-08 33.3 0.4 7.5e-08 31.8 0.3 1.9 1 0 0 1 1 1 1 Variant SH3 domain Bud13 PF09736.4 CCC69778.1 - 1 9.6 12.7 1.2 9.3 8.8 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex GBP_C PF02841.9 CCC69778.1 - 1.7 7.7 13.6 1.9 7.6 9.4 1.0 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain CAF-1_p150 PF11600.3 CCC69778.1 - 3.5 6.9 27.6 4 6.7 19.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BTV_NS2 PF04514.7 CCC69778.1 - 4.1 6.1 10.1 4.6 6.0 7.0 1.0 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF4355 PF14265.1 CCC69778.1 - 5 7.1 22.6 6.5 6.7 15.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DDRGK PF09756.4 CCC69778.1 - 6.5 6.1 20.6 7.7 5.8 14.3 1.1 1 0 0 1 1 1 0 DDRGK domain Tom37_C PF11801.3 CCC69778.1 - 7.5 6.3 7.8 8.3 6.2 5.4 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain DUF1764 PF08576.5 CCC69778.1 - 8.9 7.1 11.3 12 6.7 7.8 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) DNA_pol_E_B PF04042.11 CCC69779.1 - 2.2e-47 161.0 0.1 3.2e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B HSP20 PF00011.16 CCC69780.1 - 3.7e-16 58.8 0.3 4.9e-16 58.4 0.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Ribonuc_red_sm PF00268.16 CCC69781.1 - 6.1e-120 399.4 3.2 7.9e-120 399.0 2.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain zf-RING_2 PF13639.1 CCC69782.1 - 2.9e-13 49.4 5.9 4.7e-13 48.7 4.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCC69782.1 - 6.6e-09 35.3 4.0 1.1e-08 34.5 2.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC69782.1 - 2.4e-08 33.5 4.8 4e-08 32.8 3.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 CCC69782.1 - 4.1e-08 33.2 2.7 7.9e-08 32.2 1.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 CCC69782.1 - 3.1e-07 30.2 6.4 6.3e-07 29.3 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCC69782.1 - 5.1e-05 22.8 6.5 0.00012 21.6 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCC69782.1 - 0.0044 16.7 2.0 0.0044 16.7 1.4 2.5 2 1 1 3 3 3 1 RING-type zinc-finger Prok-RING_4 PF14447.1 CCC69782.1 - 0.0086 15.5 0.7 0.018 14.5 0.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-P11 PF03854.9 CCC69782.1 - 0.02 14.3 1.5 0.02 14.3 1.0 1.9 2 0 0 2 2 2 0 P-11 zinc finger zf-Apc11 PF12861.2 CCC69782.1 - 0.022 14.5 0.8 0.055 13.3 0.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 CCC69782.1 - 0.057 13.0 3.1 0.14 11.8 2.1 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 CCC69782.1 - 0.2 11.6 4.8 0.64 10.0 3.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 CCC69782.1 - 0.53 10.3 6.8 1.1 9.3 4.7 1.6 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 CCC69782.1 - 0.69 9.8 6.6 15 5.5 4.7 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Histone PF00125.19 CCC69783.1 - 1.1e-22 79.8 0.0 1.4e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCC69783.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PLA2_B PF01735.13 CCC69784.1 - 1.9e-221 735.4 0.4 2.8e-221 734.9 0.3 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain RTC PF01137.16 CCC69785.1 - 1.6e-60 203.7 0.0 2e-60 203.4 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 CCC69785.1 - 3.9e-32 110.3 0.0 7.2e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain PX PF00787.19 CCC69786.1 - 4e-21 74.9 0.2 1.2e-20 73.3 0.1 1.8 1 0 0 1 1 1 1 PX domain DUF2404 PF10296.4 CCC69787.1 - 3.3e-05 23.9 0.0 0.00017 21.6 0.0 2.2 1 1 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Polyketide_cyc PF03364.15 CCC69788.1 - 5.4e-18 65.2 0.0 7e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 CCC69788.1 - 5.1e-05 23.4 0.0 6.6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Herpes_gE PF02480.11 CCC69789.1 - 0.018 13.3 0.3 0.044 12.0 0.0 1.6 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 CCC69789.1 - 0.071 12.8 17.5 2.9 7.5 10.4 2.8 1 1 1 2 2 2 0 TMEM154 protein family Vpu PF00558.14 CCC69789.1 - 0.3 10.6 2.7 0.77 9.3 1.9 1.7 1 1 0 1 1 1 0 Vpu protein Topoisom_I_N PF02919.10 CCC69790.1 - 8.7e-100 332.4 0.7 8.7e-100 332.4 0.5 3.6 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 CCC69790.1 - 3.4e-86 288.1 2.8 3.4e-86 288.1 2.0 2.7 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 CCC69790.1 - 3e-33 113.2 1.0 3e-33 113.2 0.7 2.6 3 0 0 3 3 3 1 C-terminal topoisomerase domain Pkinase PF00069.20 CCC69791.1 - 8.8e-74 247.9 0.1 1.9e-73 246.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69791.1 - 7.7e-40 136.5 0.0 1.3e-39 135.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 CCC69791.1 - 2.6e-33 113.8 0.0 1.4e-17 63.3 0.0 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 CCC69791.1 - 1.3e-09 37.4 0.0 3.8e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 CCC69791.1 - 0.0083 15.2 0.0 0.016 14.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SH3_3 PF08239.6 CCC69791.1 - 0.022 14.9 0.1 0.043 14.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial SH3 domain DUF4179 PF13786.1 CCC69792.1 - 0.14 12.4 0.0 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) RNA_pol_L_2 PF13656.1 CCC69793.1 - 4.2e-25 86.9 0.0 5.3e-25 86.6 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CCC69793.1 - 5.3e-12 44.6 0.0 7e-12 44.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Thymidylate_kin PF02223.12 CCC69793.1 - 0.14 11.4 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Thymidylate kinase PAH PF02671.16 CCC69794.1 - 2.3e-46 155.1 6.7 4.5e-18 64.5 0.4 3.9 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 CCC69794.1 - 5.3e-44 148.1 0.4 2e-43 146.2 0.2 2.1 1 0 0 1 1 1 1 Sin3 family co-repressor zf-DHHC PF01529.15 CCC69795.1 - 3.3e-32 111.2 9.9 3.3e-32 111.2 6.8 1.8 1 1 0 1 1 1 1 DHHC palmitoyltransferase UXS1_N PF11803.3 CCC69795.1 - 0.075 12.7 0.2 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal Cyclin PF08613.6 CCC69796.1 - 2.7e-32 112.2 2.6 4.9e-32 111.3 1.8 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCC69796.1 - 0.0039 16.7 0.1 0.0068 15.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Alg6_Alg8 PF03155.10 CCC69797.1 - 1.2e-159 532.0 32.7 1.5e-159 531.8 22.7 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Pirin PF02678.11 CCC69798.1 - 6.1e-27 93.6 0.6 1.3e-26 92.5 0.2 1.7 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 CCC69798.1 - 1e-16 60.8 0.0 6.3e-16 58.3 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 CCC69798.1 - 7.9e-05 22.0 0.3 0.00035 20.0 0.2 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.7 CCC69798.1 - 0.0058 15.9 0.1 0.87 9.0 0.0 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF861) Kelch_3 PF13415.1 CCC69800.1 - 7.2e-33 112.0 4.6 1.1e-07 31.7 0.0 7.2 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CCC69800.1 - 1.3e-26 92.0 8.4 6.5e-05 22.6 0.1 7.0 5 2 1 6 6 6 5 Galactose oxidase, central domain DUF4110 PF13422.1 CCC69800.1 - 5.7e-26 90.1 0.0 5.7e-26 90.1 0.0 5.4 3 1 1 4 4 4 1 Domain of unknown function (DUF4110) Kelch_6 PF13964.1 CCC69800.1 - 1.4e-18 66.1 11.3 9.3e-06 25.6 0.2 5.7 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.1 CCC69800.1 - 6.8e-13 48.2 9.2 0.00093 19.0 0.2 6.0 7 1 0 7 7 7 3 Kelch motif Kelch_1 PF01344.20 CCC69800.1 - 5.4e-11 41.8 19.8 0.0043 16.5 0.2 6.5 7 0 0 7 7 7 4 Kelch motif Kelch_2 PF07646.10 CCC69800.1 - 1.1e-07 31.2 17.9 0.01 15.5 0.0 5.7 6 1 0 6 6 6 3 Kelch motif Nop25 PF09805.4 CCC69800.1 - 0.9 9.6 43.1 0.086 12.9 6.0 3.3 3 0 0 3 3 3 0 Nucleolar protein 12 (25kDa) ATP-synt_Eps PF04627.8 CCC69801.1 - 3.4e-14 52.1 0.5 4.3e-14 51.7 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain ABC_membrane PF00664.18 CCC69802.1 - 1.1e-46 159.4 8.0 1.5e-46 159.0 5.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CCC69802.1 - 2.8e-35 121.5 0.0 9e-35 119.9 0.0 1.9 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 CCC69802.1 - 1.8e-05 24.1 0.0 0.001 18.3 0.0 2.4 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.12 CCC69802.1 - 0.00067 19.1 0.1 0.06 12.7 0.0 2.9 2 1 1 3 3 3 1 IstB-like ATP binding protein ABC_ATPase PF09818.4 CCC69802.1 - 0.0018 16.9 0.1 0.0037 15.9 0.0 1.5 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_29 PF13555.1 CCC69802.1 - 0.0032 16.9 0.1 0.013 14.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 CCC69802.1 - 0.0079 15.6 0.0 0.043 13.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCC69802.1 - 0.011 15.7 0.0 0.036 14.0 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 CCC69802.1 - 0.012 15.2 0.0 0.051 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_23 PF13476.1 CCC69802.1 - 0.018 15.3 0.9 0.29 11.4 0.1 2.6 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 CCC69802.1 - 0.019 15.1 0.0 0.093 12.9 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 CCC69802.1 - 0.02 14.0 0.0 0.044 12.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCC69802.1 - 0.055 13.6 0.2 0.71 10.0 0.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 CCC69802.1 - 0.083 13.7 0.0 0.18 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 CCC69802.1 - 0.091 12.1 0.2 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain KAR9 PF08580.5 CCC69803.1 - 3.1e-105 352.9 31.4 3.3e-104 349.5 16.0 2.0 1 1 1 2 2 2 2 Yeast cortical protein KAR9 DUF4559 PF15112.1 CCC69803.1 - 0.22 10.6 7.6 1.4 8.0 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4559) PI-PLC-X PF00388.14 CCC69804.1 - 3.9e-49 165.7 0.0 8.8e-49 164.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 CCC69804.1 - 3.8e-36 123.6 0.1 1.3e-35 121.8 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 CCC69804.1 - 1.2e-05 25.2 0.4 1.2e-05 25.2 0.3 1.9 2 0 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_1 PF00036.27 CCC69804.1 - 0.0003 19.8 0.3 0.003 16.7 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 CCC69804.1 - 0.0034 17.4 0.4 0.0034 17.4 0.3 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_10 PF14788.1 CCC69804.1 - 0.023 14.3 1.3 0.062 12.9 0.9 1.8 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.1 CCC69804.1 - 0.043 13.7 1.0 0.38 10.7 0.2 2.9 2 0 0 2 2 2 0 EF-hand domain C2 PF00168.25 CCC69804.1 - 0.074 12.9 0.0 0.3 10.9 0.0 2.1 2 1 0 2 2 2 0 C2 domain RrnaAD PF00398.15 CCC69806.1 - 4.7e-67 225.7 0.0 5.6e-67 225.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 CCC69806.1 - 7e-10 38.9 0.0 1.2e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC69806.1 - 5.6e-06 26.9 0.0 1.1e-05 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 CCC69806.1 - 0.00023 20.7 0.0 0.00039 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 CCC69806.1 - 0.00034 19.7 0.0 0.0012 17.9 0.0 1.7 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 CCC69806.1 - 0.00082 18.7 0.0 0.0014 17.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 CCC69806.1 - 0.0018 17.8 0.0 0.0028 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CCC69806.1 - 0.0023 17.5 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 CCC69806.1 - 0.0029 17.3 0.0 0.0053 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCC69806.1 - 0.0056 17.1 0.0 0.014 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 CCC69806.1 - 0.016 14.1 0.1 0.56 9.0 0.0 2.1 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase Methyltransf_2 PF00891.13 CCC69806.1 - 0.02 14.0 0.1 0.12 11.5 0.0 2.1 3 0 0 3 3 3 0 O-methyltransferase Ubie_methyltran PF01209.13 CCC69806.1 - 0.04 13.0 0.1 0.18 10.9 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 CCC69806.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase AA_permease PF00324.16 CCC69807.1 - 7.2e-118 393.9 43.0 8.7e-118 393.6 29.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC69807.1 - 7.6e-33 113.6 45.0 1e-32 113.2 31.2 1.1 1 0 0 1 1 1 1 Amino acid permease HEAT PF02985.17 CCC69808.1 - 1.4e-22 77.6 5.5 0.0012 18.7 0.0 10.2 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 CCC69808.1 - 1.1e-20 73.6 0.5 1.4e-09 38.0 0.0 6.5 4 2 2 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 CCC69808.1 - 1.1e-17 63.9 10.5 8.3e-07 29.3 0.0 9.6 10 1 1 11 11 11 3 HEAT-like repeat MMS19_C PF12460.3 CCC69808.1 - 1.6e-06 27.1 8.1 0.048 12.3 0.0 4.7 3 1 1 4 4 4 2 RNAPII transcription regulator C-terminal Arm PF00514.18 CCC69808.1 - 2.1e-06 27.3 2.3 2.7 7.9 0.1 5.5 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 CCC69808.1 - 3.2e-06 27.4 0.1 0.11 12.9 0.0 5.5 5 2 2 7 7 7 1 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 CCC69808.1 - 0.00014 21.2 1.0 0.11 11.7 0.3 4.6 5 2 2 7 7 7 1 CLASP N terminal Cnd1 PF12717.2 CCC69808.1 - 0.00019 21.3 5.1 3.3 7.5 0.0 4.9 4 2 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.6 CCC69808.1 - 0.0014 18.1 0.0 0.0093 15.4 0.0 2.4 2 0 0 2 2 2 1 DNA alkylation repair enzyme DUF3385 PF11865.3 CCC69808.1 - 0.017 15.0 0.4 0.27 11.1 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3385) DnaJ-X PF14308.1 CCC69808.1 - 0.03 13.6 0.0 1.2 8.3 0.0 2.3 2 0 0 2 2 2 0 X-domain of DnaJ-containing eIF-3c_N PF05470.7 CCC69809.1 - 1e-163 545.6 19.1 1.5e-127 426.1 4.1 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 CCC69809.1 - 3.9e-09 36.7 3.3 8.8e-09 35.6 0.2 3.1 3 0 0 3 3 3 1 PCI domain DUF3404 PF11884.3 CCC69809.1 - 0.016 14.0 0.0 0.033 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3404) Methyltrn_RNA_3 PF02598.12 CCC69810.1 - 1.3e-99 333.2 0.6 1.7e-99 332.8 0.4 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase IPP-2 PF04979.9 CCC69811.1 - 7.4e-06 26.2 25.2 2.9e-05 24.3 11.7 3.0 1 1 1 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) Proteasome PF00227.21 CCC69812.1 - 2.2e-45 154.2 0.0 2.7e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCC69812.1 - 1.1e-12 47.0 0.2 1.9e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Flg_hook PF02120.11 CCC69812.1 - 0.0063 16.1 0.0 0.52 10.0 0.0 2.2 2 0 0 2 2 2 1 Flagellar hook-length control protein FliK AFOR_N PF02730.10 CCC69812.1 - 0.11 11.8 0.2 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Aldehyde ferredoxin oxidoreductase, N-terminal domain DUF3336 PF11815.3 CCC69813.1 - 2.7e-28 98.3 0.0 5.5e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CCC69813.1 - 4.9e-08 33.1 0.0 9.3e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase DUF2348 PF09807.4 CCC69814.1 - 0.029 13.4 0.0 0.055 12.5 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2348) SURF4 PF02077.10 CCC69815.1 - 3.3e-99 331.6 13.9 3.7e-99 331.4 9.6 1.0 1 0 0 1 1 1 1 SURF4 family MFS_1 PF07690.11 CCC69816.1 - 5.4e-10 38.5 44.2 6.5e-08 31.6 30.4 2.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_72 PF03198.9 CCC69817.1 - 1.2e-144 481.1 9.4 1.2e-144 481.1 6.5 1.7 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.8 CCC69817.1 - 9.3e-26 90.1 8.0 2.6e-25 88.7 5.5 1.8 1 0 0 1 1 1 1 X8 domain Glucan_synthase PF02364.10 CCC69818.1 - 0 1305.1 9.7 0 1304.5 6.7 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCC69818.1 - 1.1e-39 134.9 0.4 2.9e-39 133.6 0.3 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Glyco_hydro_17 PF00332.13 CCC69819.1 - 1.6e-09 37.2 0.4 1.6e-09 37.2 0.3 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 DUF2217 PF10265.4 CCC69819.1 - 0.18 10.5 6.6 0.29 9.8 4.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF4653 PF15546.1 CCC69819.1 - 3.3 6.9 10.2 8 5.6 5.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4653) Macoilin PF09726.4 CCC69819.1 - 3.7 5.7 10.0 4.9 5.3 6.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Nab2 PF11517.3 CCC69819.1 - 4.8 7.3 7.4 5.1 7.2 2.5 2.2 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) RAP1 PF07218.6 CCC69819.1 - 5 5.0 10.7 6.8 4.6 7.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) SR-25 PF10500.4 CCC69819.1 - 5.3 6.4 16.3 9.6 5.5 11.3 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.8 CCC69819.1 - 5.5 4.7 14.8 7.4 4.2 10.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein UCH PF00443.24 CCC69820.1 - 1.4e-53 181.7 3.9 3.2e-53 180.5 2.7 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.1 CCC69820.1 - 8e-49 165.9 7.7 8e-49 165.9 5.3 3.3 3 1 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 CCC69820.1 - 8.2e-34 117.3 2.3 1.7e-33 116.3 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 CCC69820.1 - 8.5e-30 103.8 5.9 3e-29 102.0 1.1 2.8 3 0 0 3 3 3 1 ICP0-binding domain of Ubiquitin-specific protease 7 UN_NPL4 PF11543.3 CCC69820.1 - 0.025 14.8 2.2 6.2 7.1 0.1 3.6 4 0 0 4 4 4 0 Nuclear pore localisation protein NPL4 RNA12 PF10443.4 CCC69821.1 - 1.2e-167 557.8 2.6 8.5e-167 555.0 0.6 2.1 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 CCC69821.1 - 6e-07 29.0 0.0 1.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_14 PF13173.1 CCC69821.1 - 0.00011 22.0 0.4 0.0043 16.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCC69821.1 - 0.0013 18.4 0.4 0.0075 15.9 0.1 2.4 1 1 1 2 2 2 1 Archaeal ATPase DUF3589 PF12141.3 CCC69822.1 - 4.4e-85 285.7 2.6 4.4e-85 285.7 1.8 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3589) Epimerase PF01370.16 CCC69823.1 - 1.8e-16 60.3 0.0 2.7e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCC69823.1 - 1.1e-12 47.2 0.0 1.5e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCC69823.1 - 1.6e-08 34.7 0.0 6e-08 32.8 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 CCC69823.1 - 9.4e-07 27.9 0.0 1.9e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CCC69823.1 - 4.6e-06 26.6 0.2 1.2e-05 25.2 0.0 1.8 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCC69823.1 - 0.0018 17.2 0.1 0.012 14.5 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 CCC69823.1 - 0.003 17.2 0.0 0.0052 16.4 0.0 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 CCC69823.1 - 0.0047 16.2 0.0 0.069 12.3 0.0 2.1 2 0 0 2 2 2 1 NmrA-like family DUF1617 PF07761.7 CCC69823.1 - 0.021 14.8 0.1 0.062 13.3 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1617) ABC_membrane PF00664.18 CCC69824.1 - 7.9e-36 123.8 12.5 1e-35 123.5 8.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 CCC69824.1 - 4.2e-33 114.5 0.0 7.8e-33 113.6 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 CCC69824.1 - 2.8e-08 34.0 0.1 0.0017 18.3 0.0 3.4 2 2 1 3 3 3 2 AAA domain SMC_N PF02463.14 CCC69824.1 - 2.5e-07 30.1 0.1 0.00053 19.2 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 CCC69824.1 - 0.00023 21.2 0.0 0.00053 20.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.4 CCC69824.1 - 0.0003 19.5 0.2 0.0057 15.2 0.0 2.1 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_17 PF13207.1 CCC69824.1 - 0.00088 20.0 0.0 0.002 18.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 CCC69824.1 - 0.00092 18.6 0.2 0.0024 17.3 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCC69824.1 - 0.0018 18.4 0.0 0.015 15.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 CCC69824.1 - 0.003 16.7 0.0 0.0074 15.4 0.0 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_10 PF12846.2 CCC69824.1 - 0.0048 16.3 0.1 0.016 14.6 0.0 1.7 1 1 0 1 1 1 1 AAA-like domain AAA PF00004.24 CCC69824.1 - 0.055 13.6 0.0 0.41 10.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 CCC69824.1 - 0.061 12.9 0.0 0.13 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 CCC69824.1 - 0.063 13.1 0.5 0.34 10.8 0.3 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DUF815 PF05673.8 CCC69824.1 - 0.064 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 CCC69824.1 - 0.11 12.7 0.0 0.53 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 CCC69824.1 - 0.17 11.0 0.0 0.41 9.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 CCC69824.1 - 0.41 10.9 7.9 0.28 11.4 0.5 2.9 2 1 0 3 3 3 0 AAA domain GATase_2 PF00310.16 CCC69825.1 - 7e-24 84.1 0.2 5.8e-18 64.7 0.0 2.5 2 1 0 3 3 3 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCC69825.1 - 1.6e-13 50.7 0.1 4.6e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 CCC69825.1 - 1.8e-11 43.8 0.1 3.1e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_7 PF13537.1 CCC69825.1 - 9.3e-11 41.5 0.0 1.6e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 CCC69825.1 - 2.5e-05 23.1 0.0 4.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II XLF PF09302.6 CCC69827.1 - 1.3e-06 28.3 2.3 4.2e-06 26.6 1.6 1.9 1 1 0 1 1 1 1 XLF (XRCC4-like factor) Ribosomal_S28e PF01200.13 CCC69828.1 - 1e-33 114.8 3.3 1.1e-33 114.7 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Red1 PF07964.6 CCC69829.1 - 1e-87 294.9 62.5 1.9e-86 290.8 33.8 2.6 3 0 0 3 3 3 2 Rec10 / Red1 DUF2280 PF10045.4 CCC69829.1 - 0.073 12.9 0.5 1.6 8.6 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) Myb_DNA-bind_6 PF13921.1 CCC69829.1 - 0.13 12.3 1.8 12 6.1 0.1 3.2 2 1 0 2 2 2 0 Myb-like DNA-binding domain TMA7 PF09072.5 CCC69830.1 - 7.2e-25 87.2 18.4 7.9e-25 87.1 12.8 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 Ras PF00071.17 CCC69831.1 - 9.1e-57 190.9 0.5 1.1e-56 190.7 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC69831.1 - 3.2e-22 79.2 0.2 6.8e-22 78.1 0.1 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCC69831.1 - 1.8e-15 56.6 0.5 2e-15 56.4 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCC69831.1 - 3.7e-06 26.8 0.0 1.5e-05 24.9 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCC69831.1 - 7.2e-06 25.3 0.2 9.2e-06 24.9 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCC69831.1 - 1.6e-05 24.1 0.0 3.3e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 CCC69831.1 - 0.0001 21.8 0.1 0.00067 19.1 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arch_ATPase PF01637.13 CCC69831.1 - 0.00019 21.1 0.3 0.00059 19.6 0.0 1.7 1 1 1 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 CCC69831.1 - 0.0028 17.8 0.0 0.015 15.4 0.0 2.0 1 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CCC69831.1 - 0.0065 15.9 0.6 0.044 13.2 0.4 2.1 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 CCC69831.1 - 0.015 14.4 0.0 0.049 12.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 CCC69831.1 - 0.018 14.6 0.1 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCC69831.1 - 0.045 13.7 0.0 0.069 13.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.12 CCC69831.1 - 0.078 12.5 0.3 2.7 7.4 0.0 2.3 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NACHT PF05729.7 CCC69831.1 - 0.092 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 CCC69831.1 - 0.097 12.3 0.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B KaiC PF06745.8 CCC69831.1 - 0.11 11.5 0.7 10 5.1 0.0 2.4 2 1 1 3 3 3 0 KaiC DAGK_cat PF00781.19 CCC69832.1 - 3.2e-24 84.8 0.0 5.9e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain SOBP PF15279.1 CCC69832.1 - 0.33 11.2 14.1 0.51 10.6 9.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein zf-C2H2 PF00096.21 CCC69833.1 - 6.1e-10 38.8 13.7 6e-05 23.1 2.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC69833.1 - 9.6e-09 35.1 4.6 9.6e-09 35.1 3.2 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC69833.1 - 2.1e-07 30.7 10.1 0.0026 17.9 1.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCC69833.1 - 0.021 14.7 1.1 0.021 14.7 0.7 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger BolA PF01722.13 CCC69833.1 - 0.072 13.0 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 BolA-like protein gag_pre-integrs PF13976.1 CCC69833.1 - 0.45 10.1 7.5 0.088 12.4 2.0 2.3 2 0 0 2 2 2 0 GAG-pre-integrase domain Pyocin_S PF06958.7 CCC69833.1 - 2 8.7 8.0 0.24 11.7 1.5 2.0 2 0 0 2 2 2 0 S-type Pyocin CAP_N PF01213.14 CCC69833.1 - 3.7 6.7 6.7 6 6.0 4.6 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-met PF12874.2 CCC69833.1 - 5 7.4 6.8 0.74 10.1 0.7 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type CBM_21 PF03370.8 CCC69834.1 - 6.3e-25 87.3 6.3 2e-24 85.7 4.4 1.9 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Fungal_trans PF04082.13 CCC69835.1 - 2e-43 148.1 0.3 3.8e-43 147.2 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC69835.1 - 7.3e-09 35.4 10.6 1.3e-08 34.5 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SCO1-SenC PF02630.9 CCC69835.1 - 0.019 14.6 0.0 0.07 12.7 0.0 1.9 1 0 0 1 1 1 0 SCO1/SenC SPRY PF00622.23 CCC69836.1 - 0.00031 20.8 0.1 0.0096 16.0 0.0 2.8 2 1 0 2 2 2 1 SPRY domain RRN7 PF11781.3 CCC69837.1 - 7.3e-10 38.1 0.3 1.2e-09 37.4 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Clat_adaptor_s PF01217.15 CCC69838.1 - 5.4e-57 191.4 2.2 6.5e-57 191.2 1.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Sulfate_transp PF00916.15 CCC69838.1 - 0.00011 21.2 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 Sulfate transporter family zf-UBR PF02207.15 CCC69839.1 - 8.3e-11 41.4 11.8 8.3e-11 41.4 8.2 1.9 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 CCC69839.1 - 5.5 6.9 13.7 0.04 13.7 1.6 3.2 3 0 0 3 3 3 0 Ring finger domain tRNA-synt_1b PF00579.20 CCC69840.1 - 8.7e-75 251.5 0.0 1.1e-74 251.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) HlyIII PF03006.15 CCC69841.1 - 4.9e-68 228.8 17.6 6.3e-68 228.5 12.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related CBM_21 PF03370.8 CCC69842.1 - 1.8e-24 85.9 6.6 4.7e-24 84.5 4.6 1.8 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Serglycin PF04360.7 CCC69842.1 - 0.0079 15.9 2.2 0.02 14.6 0.4 2.3 2 0 0 2 2 2 1 Serglycin Lyase_1 PF00206.15 CCC69843.1 - 1.6e-115 385.6 0.0 2.3e-115 385.1 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 CCC69843.1 - 3e-25 88.0 0.1 2.6e-24 85.0 0.1 2.3 2 0 0 2 2 2 1 Fumarase C C-terminus Peptidase_S8 PF00082.17 CCC69844.1 - 1.1e-50 172.3 0.5 1.5e-50 171.9 0.3 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CCC69844.1 - 3e-08 34.0 0.0 6.5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Acetyltransf_1 PF00583.19 CCC69845.1 - 4.5e-09 36.2 0.0 8.3e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 CCC69845.1 - 0.00077 19.1 0.1 0.18 11.5 0.0 3.1 2 1 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 CCC69845.1 - 0.0033 17.5 0.0 0.0082 16.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DNA_ligase_A_M PF01068.16 CCC69846.1 - 6.5e-49 166.0 0.1 1.2e-48 165.1 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 CCC69846.1 - 9.2e-14 51.6 0.0 1.5e-13 50.9 0.0 1.3 1 0 0 1 1 1 1 DNA ligase N terminus BRCT PF00533.21 CCC69846.1 - 1.2e-09 38.1 0.2 3.3e-05 23.9 0.0 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.10 CCC69846.1 - 1.3e-05 25.4 0.0 2.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region mRNA_cap_enzyme PF01331.14 CCC69846.1 - 0.002 17.8 2.4 0.18 11.4 1.6 2.7 1 1 0 1 1 1 1 mRNA capping enzyme, catalytic domain Fcf1 PF04900.7 CCC69847.1 - 2.2e-30 104.7 1.0 2.2e-30 104.7 0.7 2.0 2 0 0 2 2 2 1 Fcf1 TPR_11 PF13414.1 CCC69848.1 - 1.2e-20 72.9 7.0 1.5e-13 50.1 0.4 3.1 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 CCC69848.1 - 5.2e-14 50.9 5.2 0.0029 17.4 0.0 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCC69848.1 - 1.9e-09 36.7 7.1 0.002 17.6 0.4 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCC69848.1 - 1e-08 35.5 0.4 0.0084 16.7 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCC69848.1 - 4.8e-06 25.9 1.0 0.069 12.9 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCC69848.1 - 4.9e-06 26.3 4.2 0.017 15.0 0.4 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCC69848.1 - 0.00023 21.5 0.4 5.8 7.8 0.0 4.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 CCC69848.1 - 0.00033 20.2 2.2 0.15 11.9 0.7 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 CCC69848.1 - 0.00064 18.9 0.3 0.085 12.1 0.0 3.6 4 0 0 4 4 4 1 SHNi-TPR TPR_19 PF14559.1 CCC69848.1 - 0.0011 19.2 2.6 0.39 11.0 0.6 3.9 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 CCC69848.1 - 0.0031 17.5 0.7 0.097 12.9 0.0 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 CCC69848.1 - 0.0034 17.4 0.7 1.7 8.8 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 CCC69848.1 - 0.0066 16.5 0.8 0.055 13.5 0.4 2.5 2 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCC69848.1 - 0.018 15.4 4.8 6.6 7.4 0.2 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 CCC69848.1 - 0.019 14.9 1.3 24 5.0 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCC69848.1 - 0.032 14.0 2.0 3 7.8 0.0 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 CCC69848.1 - 0.043 13.7 5.3 0.33 10.8 0.2 3.4 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain Cnd1 PF12717.2 CCC69849.1 - 6.4e-50 169.4 1.5 6.4e-50 169.4 1.1 5.5 5 2 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 CCC69849.1 - 4.2e-43 146.9 2.2 9.3e-43 145.8 1.5 1.7 1 0 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 CCC69849.1 - 1.1e-11 44.7 0.0 0.00053 20.2 0.0 3.8 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.17 CCC69849.1 - 3.8e-10 38.9 1.2 0.2 11.8 0.0 5.8 5 0 0 5 5 5 3 HEAT repeat HEAT_EZ PF13513.1 CCC69849.1 - 0.00093 19.6 0.1 2.3 8.7 0.0 4.3 4 0 0 4 4 4 1 HEAT-like repeat DUF4187 PF13821.1 CCC69850.1 - 1.2e-17 63.2 1.4 2e-17 62.4 0.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) DUF1247 PF06851.6 CCC69850.1 - 0.00078 19.1 0.6 0.0011 18.6 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1247) zf-C2H2_jaz PF12171.3 CCC69850.1 - 0.017 15.2 1.2 0.032 14.3 0.9 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Flu_PB1 PF00602.12 CCC69850.1 - 0.067 10.9 0.0 0.074 10.7 0.0 1.1 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PB1 zf-C2H2_4 PF13894.1 CCC69850.1 - 0.13 12.6 0.6 0.29 11.5 0.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger DcpS PF05652.7 CCC69851.1 - 2e-41 140.8 0.0 2.9e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 CCC69851.1 - 6.2e-33 113.4 0.0 1.7e-32 112.0 0.0 1.8 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CCC69851.1 - 0.13 12.8 0.1 1.4 9.5 0.1 2.5 3 0 0 3 3 3 0 HIT domain Longin PF13774.1 CCC69852.1 - 6.4e-24 83.3 0.8 1.1e-23 82.5 0.6 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 CCC69852.1 - 1.4e-16 59.8 0.2 3.3e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 CCC69852.1 - 0.039 13.7 0.2 0.063 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3139 PF11337.3 CCC69852.1 - 0.3 11.3 2.1 0.36 11.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Zn_clus PF00172.13 CCC69853.1 - 1.4e-05 24.8 9.6 2.9e-05 23.8 6.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 CCC69854.1 - 8.1e-36 120.6 2.4 1.8e-08 33.9 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 CCC69854.1 - 3.5e-28 97.4 13.6 7.9e-28 96.3 9.4 1.6 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 CCC69854.1 - 0.00025 20.7 0.7 0.014 15.2 0.0 3.5 2 2 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region NIF PF03031.13 CCC69855.1 - 4.5e-50 169.4 0.2 1e-49 168.2 0.2 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NPCC PF08058.6 CCC69856.1 - 2.9e-31 108.2 6.1 7.7e-31 106.8 2.8 2.1 2 0 0 2 2 2 1 Nuclear pore complex component PNP_UDP_1 PF01048.15 CCC69857.1 - 3.8e-34 117.6 0.0 4.7e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily SYS1 PF09801.4 CCC69858.1 - 4.6e-48 162.8 11.7 5.5e-48 162.6 8.1 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DLIC PF05783.6 CCC69859.1 - 6.6e-07 28.3 0.2 8.9e-07 27.9 0.2 1.2 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) DUF1967 PF09269.6 CCC69859.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) COX16 PF14138.1 CCC69860.1 - 4.4e-30 103.6 1.9 5.3e-30 103.4 0.2 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase assembly protein COX16 SBDS_C PF09377.5 CCC69861.1 - 5.2e-35 119.8 0.9 5.2e-35 119.8 0.6 2.0 1 1 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 CCC69861.1 - 2.8e-33 113.5 2.6 4.6e-33 112.8 1.8 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein MoeZ_MoeB PF05237.8 CCC69861.1 - 0.05 13.2 0.1 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 MoeZ/MoeB domain chaperone_DMP PF10448.4 CCC69862.1 - 3e-29 101.7 0.4 3.4e-29 101.5 0.3 1.0 1 0 0 1 1 1 1 20S proteasome chaperone Abhydro_lipase PF04083.11 CCC69863.1 - 2.7e-17 61.8 0.0 5.4e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 CCC69863.1 - 8.1e-05 22.5 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCC69863.1 - 0.00072 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC69863.1 - 0.0054 16.3 0.1 0.063 12.8 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Adaptin_N PF01602.15 CCC69864.1 - 1.5e-96 323.8 19.9 1.9e-96 323.4 13.8 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CCC69864.1 - 4.8e-06 26.7 0.0 0.13 12.5 0.0 4.1 2 1 3 5 5 5 3 HEAT repeats Rib_hydrolayse PF02267.12 CCC69864.1 - 0.061 12.6 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 ADP-ribosyl cyclase LAGLIDADG_WhiA PF14527.1 CCC69866.1 - 0.029 14.2 0.2 0.072 12.9 0.2 1.6 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Mpp10 PF04006.7 CCC69867.1 - 3.4e-127 425.3 69.4 4.2e-127 425.0 48.1 1.0 1 0 0 1 1 1 1 Mpp10 protein Aa_trans PF01490.13 CCC69868.1 - 4.9e-81 272.3 29.1 5.9e-81 272.0 20.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein MFS_1 PF07690.11 CCC69869.1 - 2.6e-36 125.0 22.1 5.5e-36 124.0 15.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily CRPA PF05745.6 CCC69869.1 - 0.1 12.3 3.9 3.2 7.5 0.1 2.8 2 0 0 2 2 2 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Ssl1 PF04056.9 CCC69870.1 - 7.8e-90 299.6 0.1 1.1e-89 299.1 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 CCC69870.1 - 2.3e-21 75.5 11.2 2.3e-21 75.5 7.8 2.7 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 CCC69870.1 - 8.9e-13 48.7 0.0 1.2e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 CCC69870.1 - 0.019 14.7 0.0 0.035 13.8 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Taeniidae_ag PF05596.6 CCC69870.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Taeniidae antigen Ebola_NP PF05505.7 CCC69870.1 - 0.2 9.6 4.7 0.34 8.9 3.2 1.3 1 0 0 1 1 1 0 Ebola nucleoprotein CDC45 PF02724.9 CCC69870.1 - 0.59 8.0 6.0 0.8 7.6 4.1 1.1 1 0 0 1 1 1 0 CDC45-like protein IBR PF01485.16 CCC69870.1 - 2.1 8.3 17.4 0.03 14.2 3.8 2.8 2 0 0 2 2 2 0 IBR domain Tfb4 PF03850.9 CCC69870.1 - 5.1 6.2 8.7 9.2 5.4 6.0 1.4 1 0 0 1 1 1 0 Transcription factor Tfb4 zf-HIT PF04438.11 CCC69870.1 - 6.6 6.4 22.1 1.8 8.2 4.8 3.2 3 0 0 3 3 3 0 HIT zinc finger Response_reg PF00072.19 CCC69871.1 - 2.5e-20 72.5 0.0 1.2e-18 67.1 0.0 2.4 1 1 0 1 1 1 1 Response regulator receiver domain Pam16 PF03656.8 CCC69872.1 - 1.5e-06 27.9 0.1 1.9e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 CCC69872.1 - 1e-05 25.1 0.4 1.5e-05 24.6 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain BAAT_C PF08840.6 CCC69872.1 - 0.025 14.3 0.0 0.041 13.5 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal MCM PF00493.18 CCC69873.1 - 5.4e-142 472.4 0.7 8.8e-142 471.7 0.5 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCC69873.1 - 6.3e-19 68.6 0.5 2.1e-18 66.9 0.3 1.9 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.9 CCC69873.1 - 3e-06 27.0 0.1 1.3e-05 24.9 0.0 2.2 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 CCC69873.1 - 3.3e-06 26.4 0.0 0.00057 19.0 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCC69873.1 - 0.00048 19.7 0.1 0.0029 17.2 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCC69873.1 - 0.011 15.2 0.0 1.2 8.6 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF1822 PF08852.6 CCC69873.1 - 0.054 12.3 3.8 0.5 9.1 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1822) HTH_41 PF14502.1 CCC69873.1 - 0.11 12.0 0.0 0.27 10.8 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain LSM PF01423.17 CCC69874.1 - 6.2e-18 64.1 0.8 8.3e-18 63.7 0.6 1.1 1 0 0 1 1 1 1 LSM domain DEAD PF00270.24 CCC69875.1 - 2.5e-41 140.9 1.4 4.8e-41 140.0 1.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC69875.1 - 4.3e-23 80.9 0.0 1.6e-11 43.8 0.0 2.9 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 CCC69875.1 - 3.3e-06 27.0 3.3 1.4e-05 25.0 0.1 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DnaI_N PF07319.6 CCC69875.1 - 0.14 12.4 6.3 0.91 9.8 0.1 3.4 3 1 0 3 3 3 0 Primosomal protein DnaI N-terminus CPSF73-100_C PF11718.3 CCC69876.1 - 6e-62 208.8 5.1 1e-61 208.0 3.5 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 CCC69876.1 - 5.8e-33 113.5 0.1 2e-32 111.7 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 CCC69876.1 - 8.2e-18 64.7 0.7 1.5e-17 63.9 0.5 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCC69876.1 - 1.8e-13 50.4 1.0 1.2e-12 47.7 0.3 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 CCC69876.1 - 1.1e-09 38.0 0.0 2.1e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 CCC69876.1 - 4.1e-07 29.8 0.3 2e-06 27.6 0.0 2.2 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Fungal_trans PF04082.13 CCC69877.1 - 5.6e-17 61.4 6.7 1.4e-16 60.1 4.6 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC69877.1 - 2.5e-06 27.2 10.2 6.3e-06 25.9 7.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RF-1 PF00472.15 CCC69878.1 - 1.5e-19 69.8 6.6 3.3e-19 68.7 4.6 1.6 1 1 0 1 1 1 1 RF-1 domain tRNA-Thr_ED PF08915.6 CCC69879.1 - 0.079 12.9 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase Sex_peptide PF08138.6 CCC69879.1 - 0.12 12.2 0.1 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Sex peptide (SP) family DsrC PF04358.8 CCC69879.1 - 0.24 11.6 1.2 0.34 11.1 0.1 1.8 2 0 0 2 2 2 0 DsrC like protein CHD5 PF04420.9 CCC69879.1 - 4.2 6.9 7.3 0.45 10.1 0.9 2.3 3 0 0 3 3 3 0 CHD5-like protein ECH PF00378.15 CCC69880.1 - 1.6e-15 56.9 0.0 2.4e-07 30.1 0.0 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase family Syndecan PF01034.15 CCC69880.1 - 0.022 14.3 0.0 0.041 13.5 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Colipase_C PF02740.9 CCC69880.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Colipase, C-terminal domain Methyltransf_16 PF10294.4 CCC69881.1 - 2.3e-15 56.4 0.0 3.1e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 CCC69881.1 - 0.00018 21.2 0.0 0.00028 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC69881.1 - 0.0025 18.3 0.0 0.0042 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC69881.1 - 0.065 12.8 0.1 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 CCC69881.1 - 0.09 13.2 0.1 0.13 12.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Glyco_hydro_18 PF00704.23 CCC69882.1 - 3.9e-23 82.4 2.8 6.6e-23 81.7 2.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_19 PF03427.8 CCC69882.1 - 3.1e-06 26.8 3.0 3.1e-06 26.8 2.1 4.1 4 0 0 4 4 4 1 Carbohydrate binding domain (family 19) Baculo_PEP_C PF04513.7 CCC69883.1 - 0.064 13.0 8.4 1.3 8.8 2.0 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Maelstrom PF13017.1 CCC69883.1 - 0.14 11.6 1.2 0.29 10.5 0.2 2.0 2 0 0 2 2 2 0 piRNA pathway germ-plasm component Ribosomal_S30 PF04758.9 CCC69884.1 - 1.1e-29 101.9 5.0 1.2e-29 101.8 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 Hus1 PF04005.7 CCC69885.1 - 5.7e-21 74.7 0.8 7.9e-17 61.1 0.1 2.3 2 0 0 2 2 2 2 Hus1-like protein GTP_EFTU PF00009.22 CCC69886.1 - 5e-45 153.2 0.3 1e-44 152.2 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 CCC69886.1 - 1.9e-39 133.9 7.7 4.3e-39 132.7 5.3 1.7 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 CCC69886.1 - 9.7e-17 60.6 0.0 3.9e-16 58.6 0.0 2.1 2 0 0 2 2 2 1 Elongation factor G C-terminus MMR_HSR1 PF01926.18 CCC69886.1 - 0.00018 21.4 0.0 0.00056 19.8 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 CCC69886.1 - 0.00021 21.3 0.9 0.0006 19.8 0.6 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 CCC69886.1 - 0.00033 21.1 0.1 0.00096 19.6 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 CCC69886.1 - 0.00072 18.9 0.8 0.0012 18.2 0.0 1.8 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 CCC69886.1 - 0.0014 17.8 0.1 0.0065 15.7 0.0 2.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit EFG_II PF14492.1 CCC69886.1 - 0.041 13.7 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 Elongation Factor G, domain II FeoB_N PF02421.13 CCC69886.1 - 0.095 11.9 2.2 0.24 10.6 0.2 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B NAD_binding_10 PF13460.1 CCC69887.1 - 2e-08 34.4 0.0 1.6e-05 24.9 0.0 2.5 2 1 1 3 3 3 2 NADH(P)-binding Epimerase PF01370.16 CCC69887.1 - 1.2e-07 31.3 0.0 1.9e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCC69887.1 - 0.0063 15.4 0.1 0.078 11.8 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CCC69887.1 - 0.042 13.7 0.0 0.061 13.2 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 CCC69887.1 - 0.06 12.2 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 CCC69887.1 - 0.13 10.9 0.0 0.25 9.9 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TPR_1 PF00515.23 CCC69888.1 - 3.3e-05 23.2 0.7 0.15 11.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 CCC69888.1 - 0.00046 19.8 0.2 0.56 10.2 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 CCC69888.1 - 0.00072 19.1 0.4 1.6 8.4 0.0 3.2 3 0 0 3 3 3 2 TPR repeat DUF1542 PF07564.6 CCC69888.1 - 0.0094 15.9 0.6 0.032 14.2 0.0 2.1 1 1 1 2 2 2 1 Domain of Unknown Function (DUF1542) LOH1CR12 PF10158.4 CCC69888.1 - 0.014 15.2 0.1 0.027 14.2 0.1 1.4 1 0 0 1 1 1 0 Tumour suppressor protein TPR_19 PF14559.1 CCC69888.1 - 0.034 14.4 0.5 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4559 PF15112.1 CCC69888.1 - 0.1 11.7 1.1 0.14 11.2 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF4083 PF13314.1 CCC69889.1 - 0.0018 18.0 1.2 0.0036 17.0 0.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) ABC2_membrane_3 PF12698.2 CCC69889.1 - 0.0087 15.1 1.0 0.029 13.4 0.3 1.7 1 1 1 2 2 2 2 ABC-2 family transporter protein DUF975 PF06161.6 CCC69889.1 - 0.012 15.3 0.3 0.014 15.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF975) TRP PF06011.7 CCC69889.1 - 0.015 13.8 0.3 0.019 13.5 0.2 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel Baculo_11_kDa PF06143.6 CCC69889.1 - 0.047 13.0 1.5 0.079 12.3 1.0 1.4 1 0 0 1 1 1 0 Baculovirus 11 kDa family Ninjurin PF04923.7 CCC69889.1 - 0.061 13.0 0.1 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Ninjurin ATP-synt_8 PF00895.15 CCC69889.1 - 2.8 8.1 4.6 0.66 10.2 0.6 1.9 2 0 0 2 2 2 0 ATP synthase protein 8 zf-U1 PF06220.7 CCC69890.1 - 2.1e-18 65.5 5.2 5.9e-18 64.1 3.6 1.8 1 0 0 1 1 1 1 U1 zinc finger ARD PF03079.9 CCC69890.1 - 0.25 11.2 1.9 0.47 10.3 1.3 1.4 1 0 0 1 1 1 0 ARD/ARD' family G_glu_transpept PF01019.16 CCC69891.1 - 2.6e-131 438.5 0.0 3.2e-131 438.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Cellulase PF00150.13 CCC69892.1 - 2.2e-14 53.3 0.4 5e-14 52.1 0.2 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cornichon PF03311.9 CCC69894.1 - 4.6e-49 165.8 7.4 5.2e-49 165.6 5.1 1.0 1 0 0 1 1 1 1 Cornichon protein DUF1634 PF07843.6 CCC69894.1 - 0.06 12.9 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) DUF1673 PF07895.6 CCC69894.1 - 1.1 8.7 4.7 1.6 8.2 3.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) MTHFR PF02219.12 CCC69895.1 - 2.9e-122 407.2 0.0 3.9e-122 406.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Aldo_ket_red PF00248.16 CCC69896.1 - 5.2e-57 192.8 0.0 5.8e-57 192.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family T4_Gp59_C PF08994.5 CCC69896.1 - 0.014 15.5 0.1 0.03 14.4 0.0 1.5 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term CNPase PF05881.7 CCC69896.1 - 0.15 11.4 0.0 0.3 10.4 0.0 1.5 1 1 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) Scs3p PF10261.4 CCC69897.1 - 1.9e-68 230.0 9.3 2.5e-68 229.6 6.4 1.1 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM Med31 PF05669.7 CCC69898.1 - 1.7e-34 117.6 0.4 1.9e-34 117.4 0.3 1.1 1 0 0 1 1 1 1 SOH1 CPSase_L_D2 PF02786.12 CCC69899.1 - 1.7e-84 282.3 0.1 3.4e-84 281.3 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CCC69899.1 - 7.3e-66 221.3 0.0 1.2e-65 220.6 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CCC69899.1 - 4.1e-36 123.4 0.0 9.7e-36 122.2 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCC69899.1 - 1.2e-31 108.7 0.0 2.5e-30 104.5 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CCC69899.1 - 3.6e-29 102.0 0.1 9.4e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 HMGL-like ATPgrasp_Ter PF15632.1 CCC69899.1 - 2.5e-18 65.9 0.0 1.5e-17 63.3 0.0 2.2 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 CCC69899.1 - 7.7e-18 63.9 3.1 7.7e-18 63.9 2.1 2.2 3 0 0 3 3 3 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 CCC69899.1 - 5.4e-17 62.1 0.1 1e-16 61.2 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCC69899.1 - 7.1e-08 32.0 0.0 1.5e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CCC69899.1 - 9.3e-08 31.6 0.0 1.9e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CCC69899.1 - 5.3e-07 29.2 1.4 0.0028 17.2 0.2 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 CCC69899.1 - 1.5e-06 28.1 0.0 8.1e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain RimK PF08443.6 CCC69899.1 - 9.2e-06 25.2 0.0 3.1e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 CCC69899.1 - 0.0033 17.7 0.9 0.51 10.7 0.0 3.3 3 0 0 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 CCC69899.1 - 0.0043 16.4 0.5 0.45 9.7 0.1 2.6 2 0 0 2 2 2 1 HlyD family secretion protein GCV_H PF01597.14 CCC69899.1 - 0.15 11.7 0.9 0.44 10.2 0.6 1.8 1 0 0 1 1 1 0 Glycine cleavage H-protein DASH_Duo1 PF08651.5 CCC69900.1 - 1.3e-26 92.0 1.4 1.3e-26 92.0 1.0 2.2 3 0 0 3 3 3 1 DASH complex subunit Duo1 Uds1 PF15456.1 CCC69900.1 - 0.0059 16.5 5.2 0.0083 16.1 1.0 2.2 2 0 0 2 2 2 1 Up-regulated During Septation DUF1690 PF07956.6 CCC69900.1 - 0.025 14.5 12.5 0.045 13.7 0.8 2.2 2 0 0 2 2 2 0 Protein of Unknown function (DUF1690) Phage_HK97_TLTM PF06120.6 CCC69900.1 - 0.025 13.9 2.9 0.031 13.6 2.0 1.2 1 0 0 1 1 1 0 Tail length tape measure protein Lzipper-MIP1 PF14389.1 CCC69900.1 - 0.034 14.2 5.6 0.088 12.9 1.6 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Filo_VP35 PF02097.10 CCC69900.1 - 0.076 12.1 2.0 4.3 6.4 0.1 2.1 2 0 0 2 2 2 0 Filoviridae VP35 DUF4121 PF13497.1 CCC69900.1 - 0.096 11.6 0.8 0.54 9.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4121) FAM110_C PF14160.1 CCC69900.1 - 0.22 12.4 4.7 2 9.3 0.4 2.3 2 0 0 2 2 2 0 Centrosome-associated C terminus Pol_alpha_B_N PF08418.5 CCC69900.1 - 0.88 9.0 9.9 0.1 12.0 1.7 2.1 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal APC_CDC26 PF10471.4 CCC69900.1 - 1.3 9.8 9.8 0.17 12.6 2.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Kinetochor_Ybp2 PF08568.5 CCC69901.1 - 2.2e-142 475.5 24.5 2.4e-142 475.3 17.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin MCM_N PF14551.1 CCC69901.1 - 0.26 11.7 2.3 6.7 7.2 0.1 3.3 2 1 0 2 2 2 0 MCM N-terminal domain BCDHK_Adom3 PF10436.4 CCC69902.1 - 3.5e-36 124.2 1.2 7.1e-36 123.1 0.8 1.5 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 CCC69902.1 - 8e-08 31.9 0.0 0.0045 16.7 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UQ_con PF00179.21 CCC69903.1 - 3.2e-50 169.1 0.1 3.8e-50 168.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCC69903.1 - 5.1e-06 26.2 0.0 6.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 CCC69903.1 - 0.021 14.7 0.3 0.092 12.6 0.2 1.8 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 CCC69903.1 - 0.031 13.9 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 UEV domain Nucleoplasmin PF03066.10 CCC69903.1 - 5.7 6.4 13.1 7.6 6.0 9.1 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 CCC69903.1 - 6.4 6.9 9.2 11 6.2 6.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 CCC69903.1 - 7 6.4 7.4 10 5.8 5.2 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF2457 PF10446.4 CCC69903.1 - 8.9 4.9 15.0 12 4.5 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CBS PF00571.23 CCC69905.1 - 2.2e-23 81.7 0.8 3.4e-06 26.7 0.0 5.3 5 0 0 5 5 5 5 CBS domain ASCH PF04266.9 CCC69905.1 - 0.027 14.8 0.0 2.1 8.7 0.0 3.0 3 0 0 3 3 3 0 ASCH domain FA_desaturase PF00487.19 CCC69906.1 - 8.1e-18 64.7 15.1 8.1e-18 64.7 10.5 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 CCC69906.1 - 2.2e-15 56.2 0.0 4.4e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Mon1 PF03164.9 CCC69907.1 - 2.2e-125 418.5 1.2 2.8e-125 418.1 0.8 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 TMEM171 PF15471.1 CCC69907.1 - 0.0055 15.5 0.3 0.0083 14.9 0.2 1.2 1 0 0 1 1 1 1 Transmembrane protein family 171 Ribosomal_S5 PF00333.15 CCC69908.1 - 4.9e-29 99.8 2.3 4.9e-29 99.8 1.6 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CCC69908.1 - 1.2e-21 75.7 0.1 2e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Nab2 PF11517.3 CCC69909.1 - 8e-44 148.1 0.6 1.3e-43 147.4 0.4 1.3 1 0 0 1 1 1 1 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) zf-CCCH_2 PF14608.1 CCC69909.1 - 1.6e-19 69.0 68.6 8.6e-06 25.5 2.2 7.5 7 0 0 7 7 7 7 Zinc finger C-x8-C-x5-C-x3-H type DUF2508 PF10704.4 CCC69909.1 - 0.0085 16.2 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2508) DUF4051 PF13260.1 CCC69909.1 - 0.018 14.3 0.1 0.037 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4051) Shadoo PF14999.1 CCC69909.1 - 9.7 6.0 20.3 76 3.1 14.1 2.3 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective HA2 PF04408.18 CCC69911.1 - 1.1e-26 92.7 0.1 2.6e-26 91.6 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCC69911.1 - 1.4e-25 89.2 0.0 3.7e-25 87.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCC69911.1 - 5.2e-12 45.4 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCC69911.1 - 5.1e-09 35.8 0.3 8.8e-09 35.0 0.2 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCC69911.1 - 1.9e-06 28.0 0.1 6.9e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 CCC69911.1 - 6.4e-05 22.8 0.1 0.0023 17.7 0.1 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SRP54 PF00448.17 CCC69911.1 - 0.00015 21.2 0.1 0.00036 20.0 0.1 1.6 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain Flavi_DEAD PF07652.9 CCC69911.1 - 0.00037 20.2 0.1 0.00079 19.2 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain T2SE PF00437.15 CCC69911.1 - 0.0043 15.9 0.0 0.0089 14.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 CCC69911.1 - 0.0055 17.0 0.1 0.072 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 CCC69911.1 - 0.016 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 CCC69911.1 - 0.16 11.5 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC1 PF03109.11 CCC69912.1 - 6.1e-36 123.0 0.0 1.1e-35 122.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family DUF2408 PF10303.4 CCC69913.1 - 0.0009 19.3 0.2 0.0088 16.1 0.0 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2408) TcdB_N PF12918.2 CCC69913.1 - 0.11 12.6 0.7 16 5.6 0.0 2.7 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain WD40 PF00400.27 CCC69914.1 - 1e-19 69.5 18.9 2.5e-06 27.1 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat CBS PF00571.23 CCC69915.1 - 4.1e-30 103.2 4.2 3.2e-13 49.2 0.1 4.2 4 0 0 4 4 4 4 CBS domain PerB PF06590.6 CCC69915.1 - 0.047 13.9 0.0 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 PerB protein HTH_9 PF08221.6 CCC69915.1 - 0.26 11.1 3.2 1.2 9.0 0.1 3.1 4 0 0 4 4 4 0 RNA polymerase III subunit RPC82 helix-turn-helix domain OPT PF03169.10 CCC69916.1 - 2.3e-155 518.5 18.4 2.5e-155 518.4 12.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein KH_1 PF00013.24 CCC69917.1 - 7.6e-37 124.7 5.7 5.9e-12 45.0 1.0 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCC69917.1 - 3e-28 96.9 11.2 5.9e-10 38.5 1.1 3.8 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CCC69917.1 - 2.3e-10 39.9 1.0 0.037 13.5 0.0 3.6 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 CCC69917.1 - 6.6e-08 32.0 2.1 0.0059 16.2 0.1 3.5 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 CCC69917.1 - 0.03 14.1 3.0 23 4.9 0.1 3.7 3 0 0 3 3 3 0 NusA-like KH domain SLD3 PF08639.5 CCC69918.1 - 4.1e-78 263.2 29.8 7.7e-78 262.3 20.7 1.4 1 1 0 1 1 1 1 DNA replication regulator SLD3 DUF1546 PF07571.8 CCC69919.1 - 1.3e-30 105.3 0.0 2.6e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 CCC69919.1 - 1.8e-27 95.0 0.3 3.8e-27 94.0 0.2 1.6 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 CCC69919.1 - 0.00035 20.6 0.2 0.0011 18.9 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.9 CCC69919.1 - 0.0025 17.1 0.1 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family CENP-S PF15630.1 CCC69919.1 - 0.011 15.9 0.8 0.38 10.9 0.0 3.1 4 0 0 4 4 4 0 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCC69919.1 - 0.015 15.3 1.6 0.041 13.9 0.1 2.4 2 1 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DASH_Dad3 PF08656.5 CCC69920.1 - 3.5e-24 84.2 2.4 3.5e-24 84.2 1.6 1.4 2 0 0 2 2 2 1 DASH complex subunit Dad3 ING PF12998.2 CCC69920.1 - 0.0013 19.0 0.5 0.0018 18.5 0.2 1.4 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding Baculo_gp64 PF03273.8 CCC69920.1 - 0.036 12.2 0.3 0.043 12.0 0.2 1.1 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family FtsQ PF03799.10 CCC69920.1 - 0.039 14.1 0.2 0.052 13.7 0.1 1.3 1 0 0 1 1 1 0 Cell division protein FtsQ DUF1664 PF07889.7 CCC69920.1 - 0.06 13.1 0.3 0.077 12.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) WD40 PF00400.27 CCC69921.1 - 3.5e-17 61.5 9.5 1.7e-05 24.5 0.2 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Rax2 PF12768.2 CCC69921.1 - 0.0037 16.5 0.2 0.0066 15.6 0.1 1.3 1 0 0 1 1 1 1 Cortical protein marker for cell polarity eIF2A PF08662.6 CCC69921.1 - 0.0044 16.7 0.1 0.05 13.3 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A CUE PF02845.11 CCC69922.1 - 4.3e-07 29.2 0.1 1.2e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 CUE domain CAF-1_p150 PF11600.3 CCC69923.1 - 0.019 14.3 15.7 0.025 13.9 10.9 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Clathrin_H_link PF13838.1 CCC69923.1 - 0.033 14.0 3.0 0.11 12.4 0.2 2.2 2 0 0 2 2 2 0 Clathrin-H-link MAP7 PF05672.6 CCC69923.1 - 0.47 9.8 12.7 0.022 14.1 5.1 1.5 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family EF-hand_7 PF13499.1 CCC69925.1 - 1.6e-14 53.7 0.7 1.8e-09 37.5 0.2 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 CCC69925.1 - 6.3e-10 38.5 3.1 2.6e-06 26.9 0.3 3.7 1 1 3 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 CCC69925.1 - 1e-08 34.3 4.1 0.0017 18.0 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 CCC69925.1 - 3.1e-08 32.3 7.2 0.00066 18.8 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 CCC69925.1 - 2.5e-07 30.5 0.0 0.0007 19.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain FDX-ACB PF03147.9 CCC69925.1 - 0.017 15.2 0.2 0.041 14.0 0.1 1.5 1 1 0 1 1 1 0 Ferredoxin-fold anticodon binding domain EF-hand_5 PF13202.1 CCC69925.1 - 0.017 14.4 5.5 0.63 9.4 0.1 2.9 3 0 0 3 3 3 0 EF hand UPF0154 PF03672.8 CCC69925.1 - 0.033 13.8 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) p25-alpha PF05517.7 CCC69925.1 - 0.061 13.5 0.1 9.8 6.4 0.0 2.2 1 1 1 2 2 2 0 p25-alpha FliG_N PF14842.1 CCC69925.1 - 0.067 13.3 0.2 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 FliG N-terminal domain DUF4473 PF14747.1 CCC69925.1 - 0.13 12.5 0.4 0.36 11.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DUF4497 PF14924.1 CCC69925.1 - 0.14 12.5 0.1 9.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4497) Sugar_tr PF00083.19 CCC69926.1 - 7.1e-81 272.0 22.5 9e-81 271.7 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC69926.1 - 1.7e-26 92.7 18.3 1.7e-26 92.7 12.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCC69926.1 - 1.4e-09 36.6 3.9 1.4e-09 36.6 2.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Ribosomal_L18e PF00828.14 CCC69927.1 - 1.9e-34 118.8 0.2 2.7e-34 118.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 HD_3 PF13023.1 CCC69928.1 - 1.9e-36 125.2 0.0 2.4e-36 124.9 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 CCC69928.1 - 0.00048 20.1 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 HD domain CAAP1 PF15335.1 CCC69928.1 - 0.35 11.1 1.9 4.7 7.5 0.5 2.3 1 1 1 2 2 2 0 Caspase activity and apoptosis inhibitor 1 Epimerase PF01370.16 CCC69929.1 - 1.5e-18 67.1 0.0 2e-18 66.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 CCC69929.1 - 7.2e-13 48.0 0.0 3.1e-12 45.9 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.14 CCC69929.1 - 2e-11 43.1 0.0 2.6e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCC69929.1 - 5.7e-07 29.7 0.0 1.4e-06 28.4 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 CCC69929.1 - 0.00017 20.5 0.8 0.0015 17.4 0.1 2.0 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CCC69929.1 - 0.0002 20.6 0.0 0.003 16.8 0.0 2.2 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 CCC69929.1 - 0.008 16.1 0.1 0.026 14.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase F420_oxidored PF03807.12 CCC69929.1 - 0.036 14.4 0.0 0.079 13.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.16 CCC69929.1 - 0.064 12.8 0.5 0.35 10.4 0.0 2.1 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Semialdhyde_dh PF01118.19 CCC69929.1 - 0.074 13.3 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 CCC69929.1 - 0.11 12.3 0.1 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus WD40 PF00400.27 CCC69930.1 - 3.3e-35 118.7 18.2 3.4e-08 33.0 0.7 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat Apc4_WD40 PF12894.2 CCC69930.1 - 0.034 13.6 0.1 0.84 9.1 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SNF2_N PF00176.18 CCC69931.1 - 2e-81 273.0 0.8 2e-81 273.0 0.5 2.0 3 0 0 3 3 3 1 SNF2 family N-terminal domain SLIDE PF09111.5 CCC69931.1 - 2.7e-38 130.3 1.1 2.7e-38 130.3 0.7 4.1 5 2 1 6 6 6 1 SLIDE HAND PF09110.6 CCC69931.1 - 1.4e-25 89.8 3.7 1.4e-25 89.8 2.6 3.6 3 0 0 3 3 3 1 HAND Helicase_C PF00271.26 CCC69931.1 - 3.3e-16 58.8 0.0 2.3e-15 56.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC69931.1 - 5e-09 36.2 0.0 5e-09 36.2 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCC69931.1 - 1.6e-05 24.4 0.0 4.1e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 CCC69931.1 - 0.00086 18.7 0.1 0.002 17.5 0.0 1.6 1 0 0 1 1 1 1 DEAD_2 AAA_14 PF13173.1 CCC69931.1 - 0.008 16.0 0.3 0.054 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Use1 PF09753.4 CCC69932.1 - 2.1e-05 24.1 0.6 5.5e-05 22.7 0.4 1.8 1 1 0 1 1 1 1 Membrane fusion protein Use1 HAUS6_N PF14661.1 CCC69932.1 - 0.035 13.4 2.5 0.041 13.2 0.2 1.8 1 1 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus SMAP PF15477.1 CCC69932.1 - 0.82 9.9 3.4 6.3 7.1 0.2 2.5 2 0 0 2 2 2 0 Small acidic protein family DHO_dh PF01180.16 CCC69933.1 - 3.3e-93 311.8 0.0 3.7e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 CCC69933.1 - 3.3e-07 29.5 0.0 5e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 CCC69933.1 - 0.00081 18.6 0.1 0.0013 17.9 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase Polysacc_deac_1 PF01522.16 CCC69933.1 - 0.0021 17.6 0.0 0.049 13.2 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase Glu_synthase PF01645.12 CCC69933.1 - 0.0049 15.8 0.0 0.0074 15.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 CCC69933.1 - 0.0098 14.8 0.1 0.019 13.8 0.0 1.4 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 CCC69933.1 - 0.033 13.4 0.0 0.063 12.5 0.0 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein adh_short PF00106.20 CCC69934.1 - 6e-14 52.3 0.0 8e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCC69934.1 - 1.3e-06 28.1 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCC69934.1 - 0.0031 16.9 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 CCC69934.1 - 0.0068 16.2 0.0 0.0095 15.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.21 CCC69934.1 - 0.024 14.1 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 CCC69934.1 - 0.058 13.3 0.0 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding adh_short PF00106.20 CCC69935.1 - 5.3e-16 58.9 0.0 8.1e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCC69935.1 - 1.2e-07 31.5 0.0 1.8e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCC69935.1 - 0.00015 21.3 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 CCC69935.1 - 0.016 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 CCC69935.1 - 0.021 14.8 0.0 0.099 12.6 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding MTTB PF06253.6 CCC69935.1 - 0.043 11.5 0.0 0.061 11.0 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Papilloma_E5 PF03025.9 CCC69936.1 - 0.18 11.7 0.3 0.18 11.7 0.2 2.6 2 1 0 2 2 2 0 Papillomavirus E5 RCC1 PF00415.13 CCC69937.1 - 1.3e-59 198.2 0.2 2e-08 34.3 0.2 7.7 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCC69937.1 - 1.6e-34 116.7 15.0 1.1e-05 24.9 0.0 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Homeobox_KN PF05920.6 CCC69938.1 - 6.6e-16 57.7 0.2 1.3e-15 56.8 0.1 1.5 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CCC69938.1 - 0.00032 20.2 0.1 0.00073 19.1 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain RRM_1 PF00076.17 CCC69939.1 - 1.7e-13 49.9 0.1 2.8e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC69939.1 - 2.9e-12 46.3 0.0 4.8e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC69939.1 - 2.1e-09 37.0 0.1 3.6e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHD PF00628.24 CCC69940.1 - 3.5e-10 39.4 6.1 6.4e-10 38.5 4.2 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCC69940.1 - 0.024 13.9 4.7 0.039 13.2 3.3 1.4 1 0 0 1 1 1 0 PHD-finger UCH_1 PF13423.1 CCC69941.1 - 2e-45 155.5 11.5 3.8e-45 154.5 8.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 CCC69941.1 - 2e-26 93.2 0.0 1.1e-25 90.8 0.0 2.2 2 0 0 2 2 2 1 Exonuclease Spc7 PF08317.6 CCC69942.1 - 2.6e-71 239.9 16.1 2.6e-71 239.9 11.1 1.9 2 0 0 2 2 2 1 Spc7 kinetochore protein Nup96 PF12110.3 CCC69943.1 - 5.6e-52 176.6 0.2 1.1e-51 175.6 0.2 1.5 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 CCC69943.1 - 7.9e-48 161.8 0.0 1.8e-47 160.6 0.0 1.7 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 CCC69943.1 - 9.5e-14 51.6 98.6 1.3e-10 41.5 34.2 4.0 2 1 2 4 4 4 2 Nucleoporin FG repeat region ParA PF10609.4 CCC69944.1 - 5.9e-36 122.2 0.1 1.2e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCC69944.1 - 8.1e-16 58.0 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CCC69944.1 - 5.9e-06 25.5 0.0 9.1e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ AAA_31 PF13614.1 CCC69944.1 - 2.1e-05 24.5 0.0 0.0001 22.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 CCC69944.1 - 0.00054 19.0 1.3 0.0055 15.7 0.1 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase DUF258 PF03193.11 CCC69944.1 - 0.0065 15.6 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCC69944.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_26 PF13500.1 CCC69944.1 - 0.046 13.3 0.0 0.68 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain TF_Zn_Ribbon PF08271.7 CCC69944.1 - 0.06 12.6 0.3 0.16 11.2 0.2 1.8 1 0 0 1 1 1 0 TFIIB zinc-binding YhjQ PF06564.7 CCC69944.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein XLF PF09302.6 CCC69945.1 - 4.6e-15 55.8 1.6 7.5e-15 55.1 1.1 1.3 1 0 0 1 1 1 1 XLF (XRCC4-like factor) SYCE1 PF15233.1 CCC69945.1 - 0.0025 17.7 1.0 0.0068 16.3 0.7 1.8 1 0 0 1 1 1 1 Synaptonemal complex central element protein 1 MF_alpha_N PF05436.6 CCC69946.1 - 1.1e-29 101.8 0.9 1.7e-29 101.3 0.6 1.2 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus MF_alpha PF04648.7 CCC69946.1 - 2.8e-25 86.8 45.6 9.4e-05 22.3 2.0 5.2 5 0 0 5 5 5 5 Yeast mating factor alpha hormone HmuY PF14064.1 CCC69946.1 - 0.11 12.5 7.2 7.1 6.6 0.2 3.1 3 0 0 3 3 3 0 HmuY protein UQ_con PF00179.21 CCC69947.1 - 1e-17 63.8 0.0 1.1e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCC69947.1 - 0.0054 16.5 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain MAD PF05557.8 CCC69948.1 - 1.2e-30 106.3 77.9 1.4e-30 106.0 54.0 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein IncA PF04156.9 CCC69948.1 - 0.0033 17.0 16.4 0.0033 17.0 11.4 5.1 1 1 3 4 4 4 1 IncA protein DUF883 PF05957.8 CCC69948.1 - 2 8.8 8.6 0.83 10.0 0.9 3.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Clp1 PF06807.9 CCC69948.1 - 7.3 6.3 10.8 0.6 9.8 2.4 2.7 2 1 1 3 3 3 0 Pre-mRNA cleavage complex II protein Clp1 SNase PF00565.12 CCC69949.1 - 1.7e-26 92.5 0.0 2.7e-26 91.9 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Pkinase PF00069.20 CCC69950.1 - 3.4e-22 78.8 0.6 5.5e-22 78.1 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69950.1 - 4.5e-13 48.8 0.0 7.7e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF544 PF04424.8 CCC69951.1 - 6.2e-27 93.8 1.6 7e-27 93.6 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF544) Lipoprotein_17 PF04200.7 CCC69952.1 - 0.042 13.9 2.5 0.07 13.2 1.7 1.6 1 1 0 1 1 1 0 Lipoprotein associated domain Secretin PF00263.16 CCC69952.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 Bacterial type II and III secretion system protein MPC PF03650.8 CCC69953.1 - 8.2e-43 145.1 0.0 1e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) KxDL PF10241.4 CCC69954.1 - 7.6e-07 28.9 1.2 1.2e-06 28.2 0.8 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein Prp19 PF08606.6 CCC69954.1 - 0.017 14.8 0.4 0.03 14.0 0.3 1.4 1 0 0 1 1 1 0 Prp19/Pso4-like DEAD PF00270.24 CCC69955.1 - 6.2e-49 165.7 0.0 2.1e-47 160.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC69955.1 - 2.7e-29 100.8 0.0 5.5e-28 96.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 CCC69955.1 - 0.00072 18.6 15.1 0.0029 16.7 0.0 2.6 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 CCC69955.1 - 0.00093 17.7 0.1 0.00093 17.7 0.1 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF1253) AAA_19 PF13245.1 CCC69955.1 - 0.014 15.0 0.0 0.095 12.4 0.0 2.4 2 1 0 2 2 2 0 Part of AAA domain AA_permease_2 PF13520.1 CCC69956.1 - 8.9e-49 166.1 48.3 1.1e-48 165.9 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCC69956.1 - 1.6e-22 79.5 39.7 2e-22 79.1 27.5 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1129 PF06570.6 CCC69956.1 - 0.36 10.0 7.5 1.2 8.3 3.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Ribosomal_L30 PF00327.15 CCC69957.1 - 9.1e-20 69.9 2.1 1.8e-19 69.0 1.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_L30_N PF08079.7 CCC69957.1 - 7.4e-19 67.5 18.5 1.2e-18 66.8 12.8 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain DUF3035 PF11233.3 CCC69957.1 - 0.32 11.0 4.6 0.44 10.5 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) Phage_Gp23 PF10669.4 CCC69958.1 - 0.0031 17.6 3.5 0.0031 17.6 2.4 2.4 3 0 0 3 3 3 1 Protein gp23 (Bacteriophage A118) DUF2077 PF09850.4 CCC69958.1 - 0.02 14.3 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2077) HSF_DNA-bind PF00447.12 CCC69959.1 - 3.9e-33 113.7 0.3 1e-32 112.4 0.2 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding AFT PF08731.6 CCC69960.1 - 3.9e-47 159.0 4.0 2e-46 156.7 2.8 2.3 1 0 0 1 1 1 1 Transcription factor AFT DBD_Tnp_Mut PF03108.10 CCC69960.1 - 5.7e-05 22.6 0.6 0.022 14.3 0.0 2.5 2 0 0 2 2 2 2 MuDR family transposase FAR1 PF03101.10 CCC69960.1 - 0.0013 19.1 0.6 0.0082 16.6 0.4 2.4 1 0 0 1 1 1 1 FAR1 DNA-binding domain RNA_POL_M_15KD PF02150.11 CCC69961.1 - 1.3e-16 59.9 4.0 1.3e-16 59.9 2.8 2.6 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 CCC69961.1 - 1.6e-13 49.9 15.5 1.7e-13 49.9 2.1 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 CCC69961.1 - 0.00044 20.5 2.3 0.0099 16.1 0.1 2.2 2 0 0 2 2 2 1 Restriction alleviation protein Lar DUF2387 PF09526.5 CCC69961.1 - 0.0013 18.5 3.3 0.059 13.2 0.3 2.3 2 0 0 2 2 2 1 Probable metal-binding protein (DUF2387) Rubredoxin PF00301.15 CCC69961.1 - 0.008 16.0 4.2 18 5.3 0.1 4.0 4 0 0 4 4 4 0 Rubredoxin DZR PF12773.2 CCC69961.1 - 0.013 15.3 8.3 0.18 11.6 0.3 2.5 2 1 0 2 2 2 0 Double zinc ribbon zf-UBP PF02148.14 CCC69961.1 - 0.03 14.4 3.4 0.61 10.2 0.2 2.3 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein zf-CHY PF05495.7 CCC69961.1 - 0.043 13.9 5.5 0.38 10.9 0.8 2.3 2 0 0 2 2 2 0 CHY zinc finger Zn-ribbon_8 PF09723.5 CCC69961.1 - 0.081 12.8 8.4 3.3 7.7 0.2 3.9 4 0 0 4 4 4 0 Zinc ribbon domain C1_4 PF07975.7 CCC69961.1 - 0.083 12.9 10.9 0.28 11.1 0.7 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain IBR PF01485.16 CCC69961.1 - 0.13 12.1 6.2 1.1 9.1 0.3 2.5 2 1 0 2 2 2 0 IBR domain Cytochrom_c3_2 PF14537.1 CCC69961.1 - 0.15 12.4 2.7 0.29 11.5 0.3 2.1 2 0 0 2 2 2 0 Cytochrome c3 Zn_Tnp_IS1595 PF12760.2 CCC69961.1 - 0.16 11.8 11.4 5.1 6.9 0.6 3.1 2 1 1 3 3 3 0 Transposase zinc-ribbon domain zf-CSL PF05207.8 CCC69961.1 - 0.2 11.1 4.7 2 8.0 0.2 2.3 2 0 0 2 2 2 0 CSL zinc finger Cytochrome_C7 PF14522.1 CCC69961.1 - 0.48 10.0 4.2 0.59 9.8 0.2 2.3 2 1 0 2 2 2 0 Cytochrome c7 GFA PF04828.9 CCC69961.1 - 1.9 8.5 6.1 5.8 6.9 0.8 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Rpr2 PF04032.11 CCC69961.1 - 1.9 8.4 7.1 1.1e+02 2.8 4.9 2.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Nudix_N_2 PF14803.1 CCC69961.1 - 3.2 7.5 9.8 3.2 7.5 0.6 3.2 3 0 0 3 3 3 0 Nudix N-terminal HypA PF01155.14 CCC69961.1 - 5.1 6.8 8.0 33 4.2 2.8 3.0 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Cytochrom_NNT PF03264.9 CCC69961.1 - 7.7 5.9 7.7 0.21 11.0 0.4 2.0 2 1 0 2 2 2 0 NapC/NirT cytochrome c family, N-terminal region Ribosomal_L12 PF00542.14 CCC69962.1 - 8.8e-20 70.4 8.3 8.8e-20 70.4 5.7 1.6 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_60s PF00428.14 CCC69962.1 - 0.029 14.7 4.4 0.029 14.7 3.0 2.6 1 1 2 3 3 3 0 60s Acidic ribosomal protein Enoyl_reductase PF12241.3 CCC69962.1 - 0.053 12.4 0.2 0.078 11.9 0.1 1.2 1 0 0 1 1 1 0 Trans-2-enoyl-CoA reductase catalytic region Bindin PF02084.10 CCC69962.1 - 0.067 13.2 0.4 0.095 12.7 0.2 1.1 1 0 0 1 1 1 0 Bindin Pkinase PF00069.20 CCC69963.1 - 1.7e-41 142.1 0.0 2.9e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC69963.1 - 4.2e-15 55.5 0.0 6.8e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCC69963.1 - 0.014 15.1 0.0 0.074 12.7 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family GDC-P PF02347.11 CCC69964.1 - 9.8e-190 630.7 0.0 1.3e-179 597.4 0.0 2.5 2 1 0 2 2 2 2 Glycine cleavage system P-protein Cys_Met_Meta_PP PF01053.15 CCC69964.1 - 0.00016 20.0 0.0 0.00026 19.4 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ribosomal_S17 PF00366.15 CCC69965.1 - 3.3e-15 55.8 0.4 6.9e-15 54.8 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 DUF4099 PF13351.1 CCC69965.1 - 0.034 14.0 1.4 7.3 6.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4099) DNA_topoisoIV PF00521.15 CCC69965.1 - 0.1 11.3 9.7 0.13 11.1 6.7 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Fib_alpha PF08702.5 CCC69965.1 - 2 8.5 8.9 6.5 6.8 6.1 1.9 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Glyco_hydro_16 PF00722.16 CCC69966.1 - 1.4e-22 79.9 2.2 3.3e-22 78.6 1.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PAP1 PF08601.5 CCC69966.1 - 5.2 6.6 16.6 8.6 5.9 11.5 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 RINGv PF12906.2 CCC69967.1 - 0.00014 21.7 5.3 0.0003 20.7 3.7 1.5 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 CCC69967.1 - 0.083 12.7 7.1 0.12 12.1 3.0 2.2 2 0 0 2 2 2 0 Ring finger domain zf-RING_4 PF14570.1 CCC69967.1 - 0.69 9.5 6.4 11 5.6 1.9 2.4 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain HSP90 PF00183.13 CCC69968.1 - 3.3e-255 847.5 37.3 3.9e-255 847.2 25.9 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 CCC69968.1 - 5.5e-11 42.2 0.0 1.9e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCC69968.1 - 7.5e-11 41.7 0.0 1.4e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_S10 PF00450.17 CCC69968.1 - 0.064 12.4 0.2 0.15 11.1 0.0 1.6 2 0 0 2 2 2 0 Serine carboxypeptidase DUF2435 PF10363.4 CCC69969.1 - 3.6e-28 97.2 5.5 1.6e-27 95.2 0.4 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 CCC69969.1 - 1.6e-09 37.0 3.0 4.9e-09 35.4 2.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) GLTSCR1 PF15249.1 CCC69969.1 - 0.33 11.0 4.7 7.7 6.6 1.5 2.7 2 0 0 2 2 2 0 Glioma tumor suppressor candidate region SNARE PF05739.14 CCC69971.1 - 2.2e-15 56.0 8.6 2.2e-15 56.0 5.9 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 CCC69971.1 - 2.5e-07 30.8 8.1 2.5e-07 30.8 5.6 2.9 2 1 1 3 3 3 1 Syntaxin Synaptobrevin PF00957.16 CCC69971.1 - 0.00019 20.9 1.4 0.00019 20.9 1.0 2.5 2 0 0 2 2 2 1 Synaptobrevin Rifin_STEVOR PF02009.11 CCC69971.1 - 0.0033 17.1 5.0 0.0033 17.1 3.4 1.6 1 1 0 1 1 1 1 Rifin/stevor family DUF4094 PF13334.1 CCC69971.1 - 0.014 15.8 0.8 0.014 15.8 0.5 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4094) T2SF PF00482.18 CCC69971.1 - 0.073 12.9 2.6 0.25 11.2 1.8 1.8 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF2730 PF10805.3 CCC69971.1 - 0.1 12.3 5.1 0.18 11.5 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) DUF2562 PF10814.3 CCC69971.1 - 0.11 12.4 2.6 0.24 11.3 1.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2562) Allexi_40kDa PF05549.6 CCC69971.1 - 0.3 10.3 12.9 0.11 11.7 2.5 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Reo_sigmaC PF04582.7 CCC69971.1 - 0.37 9.9 3.9 2.9 6.9 0.3 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF2277 PF10041.4 CCC69971.1 - 0.55 10.2 4.4 9.7 6.2 0.0 3.3 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2277) DUF3332 PF11810.3 CCC69971.1 - 2.9 7.5 11.0 0.25 10.9 1.4 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF3332) DUF2116 PF09889.4 CCC69971.1 - 3.1 7.6 4.4 2.2 8.1 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) YecM PF06185.7 CCC69971.1 - 5 6.2 7.8 1.2 8.2 0.8 2.6 2 1 1 3 3 3 0 YecM protein zf-C2H2 PF00096.21 CCC69972.1 - 1.5e-08 34.4 12.8 0.00028 21.0 2.1 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC69972.1 - 8.2e-08 32.1 2.9 8.2e-08 32.1 2.0 2.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC69972.1 - 8.3e-08 32.0 10.8 0.00034 20.7 1.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger DUF1586 PF07625.6 CCC69972.1 - 0.16 11.7 0.4 0.16 11.7 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1586) zf-met PF12874.2 CCC69972.1 - 3.2 8.1 4.9 2.8 8.2 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type mRNA_triPase PF02940.10 CCC69974.1 - 5.5e-13 49.1 2.4 4.1e-11 43.0 1.2 2.2 1 1 1 2 2 2 2 mRNA capping enzyme, beta chain XLF PF09302.6 CCC69974.1 - 0.096 12.4 1.1 3.5 7.3 0.0 2.3 1 1 1 2 2 2 0 XLF (XRCC4-like factor) LpxC PF03331.8 CCC69975.1 - 0.0075 15.2 1.2 0.013 14.4 0.8 1.2 1 0 0 1 1 1 1 UDP-3-O-acyl N-acetylglycosamine deacetylase ABC_tran PF00005.22 CCC69976.1 - 2.3e-49 167.2 0.0 8.6e-26 90.8 0.0 3.8 2 2 0 2 2 2 2 ABC transporter SMC_N PF02463.14 CCC69976.1 - 3.6e-13 49.2 0.1 0.00084 18.6 0.0 3.5 3 0 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCC69976.1 - 1.4e-12 48.1 12.0 0.00015 21.8 0.2 4.4 3 2 1 4 4 3 3 AAA domain Chromo PF00385.19 CCC69976.1 - 6e-09 35.4 2.7 1.3e-08 34.3 1.8 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_29 PF13555.1 CCC69976.1 - 5.8e-08 32.1 0.1 0.015 14.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 CCC69976.1 - 5.9e-08 33.2 0.9 0.006 16.9 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 CCC69976.1 - 1.4e-07 31.2 0.3 0.24 10.7 0.0 4.3 4 1 0 4 4 4 2 AAA-like domain AAA_15 PF13175.1 CCC69976.1 - 5.5e-07 28.9 1.0 0.067 12.2 0.0 4.3 3 1 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 CCC69976.1 - 8.6e-07 29.7 0.0 0.055 14.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 CCC69976.1 - 1.8e-06 27.8 0.0 0.044 13.7 0.0 3.5 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 CCC69976.1 - 2.4e-06 26.8 0.0 0.013 14.6 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCC69976.1 - 1.2e-05 25.4 0.1 0.1 12.7 0.0 3.5 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 CCC69976.1 - 2.4e-05 24.8 0.0 0.1 13.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein ArgK PF03308.11 CCC69976.1 - 0.00024 19.9 0.1 0.55 8.9 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_33 PF13671.1 CCC69976.1 - 0.0003 20.6 0.0 0.89 9.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CCC69976.1 - 0.00041 20.0 0.0 0.28 10.8 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 CCC69976.1 - 0.00047 20.1 0.0 0.39 10.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCC69976.1 - 0.00048 20.2 0.0 1.3 9.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase DUF87 PF01935.12 CCC69976.1 - 0.00058 19.7 3.3 0.043 13.6 0.0 3.6 4 0 0 4 4 3 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 CCC69976.1 - 0.00075 19.3 0.0 0.23 11.2 0.0 3.5 2 1 0 2 2 2 1 Dynamin family NACHT PF05729.7 CCC69976.1 - 0.00077 19.1 0.1 0.89 9.1 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 CCC69976.1 - 0.0011 19.2 0.1 0.47 10.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 CCC69976.1 - 0.0013 18.5 0.2 3.3 7.6 0.0 3.6 2 2 1 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 CCC69976.1 - 0.0018 18.4 0.0 3.1 7.9 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 CCC69976.1 - 0.0025 17.4 1.8 2.4 7.6 0.2 3.3 3 1 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 CCC69976.1 - 0.0049 16.6 0.0 2.7 7.6 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 CCC69976.1 - 0.013 14.5 0.1 4 6.4 0.0 2.8 3 0 0 3 3 3 0 Zeta toxin AAA_14 PF13173.1 CCC69976.1 - 0.015 15.2 0.2 3.7 7.4 0.0 3.2 3 1 0 3 3 2 0 AAA domain DUF815 PF05673.8 CCC69976.1 - 0.017 14.0 0.1 2.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_ATPase PF09818.4 CCC69976.1 - 0.023 13.2 0.8 0.093 11.2 0.0 2.3 2 1 0 2 2 2 0 Predicted ATPase of the ABC class DUF3580 PF12117.3 CCC69976.1 - 0.031 14.2 3.1 0.73 9.7 0.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3580) FtsK_SpoIIIE PF01580.13 CCC69976.1 - 0.034 13.6 0.2 3.3 7.1 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 CCC69976.1 - 0.047 13.6 2.8 0.7 9.8 0.2 3.2 3 1 0 3 3 3 0 AAA ATPase domain AAA_25 PF13481.1 CCC69976.1 - 0.055 12.8 0.0 7.4 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 CCC69976.1 - 0.061 12.6 0.2 0.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Thymidylate kinase NTPase_1 PF03266.10 CCC69976.1 - 0.072 12.7 0.1 9.8 5.8 0.0 2.8 3 0 0 3 3 3 0 NTPase PduV-EutP PF10662.4 CCC69976.1 - 0.087 12.3 0.0 11 5.4 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MutS_V PF00488.16 CCC69976.1 - 0.15 11.4 0.1 12 5.2 0.0 2.3 2 0 0 2 2 2 0 MutS domain V Polysacc_synt_4 PF04669.8 CCC69977.1 - 6.5e-22 77.8 1.8 4.1e-21 75.2 1.2 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis Cation_efflux PF01545.16 CCC69978.1 - 4.2e-44 150.7 3.5 5.7e-44 150.2 2.5 1.2 1 0 0 1 1 1 1 Cation efflux family DUF2416 PF10315.4 CCC69978.1 - 0.083 13.1 0.1 0.28 11.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2416) ARID PF01388.16 CCC69979.1 - 5.9e-25 86.9 0.0 3.3e-24 84.5 0.0 2.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjC PF02373.17 CCC69979.1 - 7.5e-13 48.7 0.2 8.7e-08 32.4 0.0 3.1 1 1 1 2 2 2 2 JmjC domain, hydroxylase PHD PF00628.24 CCC69979.1 - 1.4e-07 31.1 6.1 3.4e-07 29.8 4.2 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CCC69979.1 - 0.11 12.6 1.6 0.29 11.2 1.1 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.17 CCC69979.1 - 9.9 5.9 7.5 0.85 9.4 1.6 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_L19 PF01245.15 CCC69980.1 - 1.3e-11 44.2 0.3 1.8e-11 43.7 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 DUF4548 PF15081.1 CCC69980.1 - 0.052 13.0 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) Inhibitor_I34 PF10466.4 CCC69981.1 - 3.3e-10 39.9 7.8 4.5e-10 39.4 5.4 1.3 1 0 0 1 1 1 1 Saccharopepsin inhibitor I34 DUF3552 PF12072.3 CCC69981.1 - 0.25 10.5 8.1 0.28 10.3 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) DUF3560 PF12083.3 CCC69981.1 - 0.25 11.3 5.6 0.4 10.7 3.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3560) DUF3810 PF12725.2 CCC69981.1 - 0.77 8.5 3.3 0.74 8.6 2.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ALMS_motif PF15309.1 CCC69981.1 - 2 8.2 8.2 2.4 8.0 5.7 1.1 1 0 0 1 1 1 0 ALMS motif DUF4573 PF15140.1 CCC69982.1 - 8.3e-13 48.2 0.0 0.41 10.2 0.0 6.0 1 1 6 7 7 7 7 Domain of unknown function (DUF4573) GCR1_C PF12550.3 CCC69983.1 - 5.3e-24 83.9 0.8 1.1e-23 82.8 0.6 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes SDA1 PF05285.7 CCC69983.1 - 0.29 10.3 23.3 0.66 9.2 16.1 1.5 1 0 0 1 1 1 0 SDA1 DUF2890 PF11081.3 CCC69983.1 - 9 6.3 16.0 4 7.4 8.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) TRP PF06011.7 CCC69984.1 - 7e-149 496.1 37.4 1.1e-148 495.4 26.0 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 CCC69984.1 - 1.2e-44 151.7 0.8 2.1e-44 151.0 0.5 1.4 1 0 0 1 1 1 1 ML-like domain TMEMspv1-c74-12 PF11044.3 CCC69984.1 - 0.072 12.6 1.2 0.16 11.5 0.0 2.3 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF2721 PF11026.3 CCC69984.1 - 0.079 12.5 0.1 0.079 12.5 0.1 4.9 4 1 1 5 5 5 0 Protein of unknown function (DUF2721) Coatomer_WDAD PF04053.9 CCC69986.1 - 3.2e-164 546.9 2.8 4.3e-164 546.5 1.9 1.2 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 CCC69986.1 - 8.8e-25 85.6 4.6 6.3e-09 35.3 0.0 5.7 6 0 0 6 6 6 3 WD domain, G-beta repeat TPR_11 PF13414.1 CCC69986.1 - 0.031 13.9 0.3 0.36 10.4 0.0 2.5 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 CCC69986.1 - 0.048 13.5 1.7 7.9 6.6 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat FtsJ PF01728.14 CCC69987.1 - 1.6e-54 184.6 0.0 2e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 CCC69987.1 - 0.0028 17.3 0.0 0.0088 15.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC69987.1 - 0.024 14.2 0.0 5.9 6.4 0.1 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 CCC69987.1 - 0.045 14.3 0.0 0.17 12.4 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Cyclin PF08613.6 CCC69988.1 - 1.3e-19 71.0 0.5 2.9e-19 69.9 0.4 1.6 1 0 0 1 1 1 1 Cyclin Ku_PK_bind PF08785.6 CCC69988.1 - 0.0027 17.6 0.6 0.039 13.8 0.2 2.4 2 0 0 2 2 2 1 Ku C terminal domain like Cyclin_N PF00134.18 CCC69988.1 - 0.11 12.0 1.4 0.36 10.3 1.0 1.9 1 1 0 1 1 1 0 Cyclin, N-terminal domain WAC_Acf1_DNA_bd PF10537.4 CCC69989.1 - 9.5e-38 128.4 0.4 4.9e-37 126.1 0.3 2.3 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 CCC69989.1 - 2.2e-16 59.3 0.1 7.6e-16 57.6 0.1 1.9 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 CCC69989.1 - 8.7e-07 28.6 0.2 2.8e-06 27.0 0.1 2.0 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 CCC69989.1 - 0.038 13.9 0.1 0.11 12.4 0.1 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 BAH PF01426.13 CCC69990.1 - 1.5e-16 60.2 0.2 7.1e-16 58.0 0.1 2.3 1 0 0 1 1 1 1 BAH domain zf-HC5HC2H_2 PF13832.1 CCC69990.1 - 6.4e-15 55.1 26.3 5.1e-12 45.7 2.3 4.3 4 0 0 4 4 4 3 PHD-zinc-finger like domain PHD PF00628.24 CCC69990.1 - 1.4e-13 50.3 53.3 6.9e-07 28.8 9.8 5.3 4 1 0 4 4 4 3 PHD-finger zf-HC5HC2H PF13771.1 CCC69990.1 - 1.4e-11 44.3 23.1 7e-08 32.5 0.7 4.2 3 0 0 3 3 3 3 PHD-like zinc-binding domain C1_1 PF00130.17 CCC69990.1 - 1.1e-05 25.0 4.9 1.1e-05 25.0 3.4 6.6 7 0 0 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.1 CCC69990.1 - 1.9e-05 23.8 22.3 6.6e-05 22.1 2.8 4.8 3 1 0 3 3 3 2 PHD-finger mRNA_cap_enzyme PF01331.14 CCC69991.1 - 5.1e-60 202.4 0.2 9.2e-60 201.6 0.1 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 CCC69991.1 - 2.5e-22 79.1 0.2 2.9e-21 75.7 0.1 2.3 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 CCC69991.1 - 6.4e-09 35.4 0.0 6.2e-08 32.2 0.0 2.5 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DAP3 PF10236.4 CCC69992.1 - 5.5e-79 265.3 1.0 7.3e-79 264.8 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 CCC69992.1 - 1.9e-05 24.7 0.0 3.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CCC69992.1 - 0.002 18.3 0.0 0.0049 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CCC69992.1 - 0.0044 16.6 0.0 0.029 14.0 0.0 2.4 4 0 0 4 4 4 1 NACHT domain AAA_22 PF13401.1 CCC69992.1 - 0.0071 16.4 0.1 0.029 14.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 CCC69992.1 - 0.01 15.5 0.2 0.081 12.6 0.0 2.5 2 0 0 2 2 2 1 NTPase IstB_IS21 PF01695.12 CCC69992.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 CCC69992.1 - 0.047 13.4 0.0 0.12 12.0 0.0 1.7 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 CCC69992.1 - 0.057 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCC69992.1 - 0.065 12.9 0.1 0.21 11.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 CCC69992.1 - 0.11 12.2 1.5 0.23 11.1 0.2 2.1 2 1 0 2 2 2 0 Archaeal ATPase AAA_25 PF13481.1 CCC69992.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PseudoU_synth_1 PF01416.15 CCC69993.1 - 2.2e-22 79.4 0.0 2.8e-10 40.5 0.0 2.3 2 0 0 2 2 2 2 tRNA pseudouridine synthase DEAD PF00270.24 CCC69994.1 - 6e-32 110.4 0.2 1.3e-31 109.3 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC69994.1 - 9.2e-16 57.4 0.0 2.5e-15 56.1 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC69994.1 - 3.8e-09 36.6 0.2 1.1e-08 35.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCC69994.1 - 1.5e-08 33.8 0.2 2.4e-08 33.1 0.2 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 CCC69994.1 - 0.0063 16.6 0.1 0.037 14.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain CobA_CobO_BtuR PF02572.10 CCC69994.1 - 0.1 12.2 0.1 5.8 6.5 0.0 2.3 2 0 0 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Glycos_transf_1 PF00534.15 CCC69995.1 - 3.8e-29 101.2 0.0 5.6e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 CCC69995.1 - 4.4e-07 29.7 0.0 1.2e-06 28.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 CCC69995.1 - 0.00027 21.0 0.0 0.0018 18.4 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 DUF3524 PF12038.3 CCC69995.1 - 0.14 11.7 1.3 0.54 9.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3524) Toxin_22 PF08092.6 CCC69995.1 - 0.16 11.8 0.3 0.36 10.7 0.2 1.6 1 0 0 1 1 1 0 Magi peptide toxin family SCA7 PF08313.7 CCC69996.1 - 2.4e-33 113.5 1.2 2.4e-33 113.5 0.8 2.3 2 0 0 2 2 2 1 SCA7, zinc-binding domain DUF2457 PF10446.4 CCC69996.1 - 0.0014 17.4 24.4 0.0014 17.4 16.9 3.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2457) Bud13 PF09736.4 CCC69996.1 - 0.0053 17.0 7.6 0.0053 17.0 5.3 4.1 3 1 1 4 4 4 1 Pre-mRNA-splicing factor of RES complex Nucleoplasmin PF03066.10 CCC69996.1 - 0.66 9.4 19.6 2.3 7.7 13.6 2.0 1 0 0 1 1 1 0 Nucleoplasmin NUDIX PF00293.23 CCC69998.1 - 5.4e-11 42.2 0.1 1.3e-10 41.0 0.1 1.6 1 1 0 1 1 1 1 NUDIX domain zf-NADH-PPase PF09297.6 CCC69998.1 - 0.00016 21.1 0.7 0.00087 18.7 0.0 2.4 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain DUF3323 PF11796.3 CCC69998.1 - 0.083 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) Helicase_Sgs1 PF11408.3 CCC69999.1 - 1.1e-26 92.5 0.1 2.8e-26 91.1 0.1 1.8 1 0 0 1 1 1 1 Sgs1 RecQ helicase RQC PF09382.5 CCC69999.1 - 1e-24 86.3 0.2 2.5e-24 85.0 0.1 1.7 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 CCC69999.1 - 6.9e-22 77.7 0.1 1.1e-20 73.8 0.0 2.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC69999.1 - 3.7e-21 74.7 0.0 4.1e-19 68.2 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HRDC PF00570.18 CCC69999.1 - 0.00024 20.7 0.0 0.00057 19.5 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Fungal_trans PF04082.13 CCC70000.1 - 1.1e-27 96.5 6.8 1.1e-27 96.5 4.7 2.2 2 1 1 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC70000.1 - 9.3e-10 38.2 13.8 1.7e-09 37.4 9.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 CCC70000.1 - 2.1e-08 33.9 2.2 5.8e-08 32.5 1.6 1.8 1 0 0 1 1 1 1 Gal4-like dimerisation domain MscS_porin PF12795.2 CCC70001.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain gpW PF02831.10 CCC70001.1 - 0.064 12.8 0.2 17 5.0 0.0 2.8 3 0 0 3 3 3 0 gpW RabGAP-TBC PF00566.13 CCC70002.1 - 5.9e-18 65.1 1.4 5.9e-18 65.1 1.0 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Macoilin PF09726.4 CCC70002.1 - 0.038 12.2 7.9 0.064 11.5 5.5 1.3 1 0 0 1 1 1 0 Transmembrane protein Ribosomal_L28 PF00830.14 CCC70003.1 - 2.3e-21 75.3 1.4 5.8e-21 74.0 1.0 1.7 1 0 0 1 1 1 1 Ribosomal L28 family Ribosomal_L36e PF01158.13 CCC70004.1 - 3.2e-37 126.4 4.8 3.6e-37 126.2 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DUF1903 PF08991.5 CCC70005.1 - 1.8e-20 72.8 1.8 2e-20 72.6 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) CHCH PF06747.8 CCC70005.1 - 0.085 12.7 5.8 0.15 11.9 1.2 2.3 2 0 0 2 2 2 0 CHCH domain FAM176 PF14851.1 CCC70006.1 - 1.5 8.4 4.8 1.3 8.6 2.6 1.4 1 1 0 1 1 1 0 FAM176 family Oxidored_FMN PF00724.15 CCC70007.1 - 8e-106 353.8 0.0 9.2e-106 353.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glyco_hydro_63 PF03200.11 CCC70008.1 - 1.1e-05 23.5 12.6 8.8e-05 20.5 0.5 4.2 4 1 0 4 4 4 3 Mannosyl oligosaccharide glucosidase V-SNARE_C PF12352.3 CCC70009.1 - 3.3e-19 68.7 4.7 7.4e-19 67.5 2.0 2.3 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 CCC70009.1 - 1.2e-18 66.9 2.7 1.2e-18 66.9 1.9 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus ICA69 PF04629.9 CCC70009.1 - 0.038 13.9 1.9 0.047 13.6 1.3 1.3 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain Sec20 PF03908.8 CCC70009.1 - 0.039 13.6 0.7 0.039 13.6 0.5 2.2 2 1 1 3 3 3 0 Sec20 DUF1744 PF08490.7 CCC70009.1 - 0.055 12.0 0.5 0.12 10.8 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1744) Snapin_Pallidin PF14712.1 CCC70009.1 - 0.17 12.2 7.9 0.057 13.7 2.0 2.3 2 1 0 2 2 2 0 Snapin/Pallidin GP41 PF00517.12 CCC70009.1 - 0.21 11.1 1.9 0.28 10.7 0.0 2.0 2 1 0 2 2 2 0 Retroviral envelope protein YqjK PF13997.1 CCC70009.1 - 0.48 10.6 3.2 0.81 9.9 0.0 2.5 3 0 0 3 3 3 0 YqjK-like protein CENP-F_leu_zip PF10473.4 CCC70009.1 - 0.51 10.1 9.9 0.04 13.7 1.9 2.2 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cyclin_N PF00134.18 CCC70011.1 - 2.2e-38 130.6 0.0 4.8e-38 129.5 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain RXT2_N PF08595.6 CCC70011.1 - 3.5 7.4 8.0 0.95 9.2 1.4 2.4 3 0 0 3 3 3 0 RXT2-like, N-terminal Rot1 PF10681.4 CCC70012.1 - 8.9e-95 316.0 0.1 1e-94 315.8 0.1 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal XPA_C PF05181.7 CCC70013.1 - 2.3e-26 91.1 0.2 2.3e-26 91.1 0.1 1.8 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 CCC70013.1 - 0.011 15.3 0.7 0.011 15.3 0.5 1.9 2 0 0 2 2 2 0 XPA protein N-terminal ERG2_Sigma1R PF04622.7 CCC70014.1 - 9.4e-92 306.1 0.9 1.1e-91 305.8 0.6 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Porin_3 PF01459.17 CCC70015.1 - 2.2e-82 276.4 0.2 2.5e-82 276.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic porin Inp1 PF12634.2 CCC70016.1 - 3e-41 140.4 0.3 3e-41 140.4 0.2 2.8 2 0 0 2 2 2 1 Inheritance of peroxisomes protein 1 Pox_RNA_Pol_19 PF05320.7 CCC70016.1 - 0.59 9.8 17.1 0.098 12.4 1.0 3.0 2 2 0 3 3 3 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PFK PF00365.15 CCC70017.1 - 3.1e-167 554.6 2.5 1e-123 411.8 1.7 2.5 3 0 0 3 3 3 2 Phosphofructokinase DUF1767 PF08585.7 CCC70018.1 - 0.058 13.6 0.2 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1767) ACC_central PF08326.7 CCC70019.1 - 4.2e-260 864.7 0.0 6.4e-260 864.1 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 CCC70019.1 - 1.7e-177 590.6 0.0 2.5e-177 590.1 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 CCC70019.1 - 1.3e-53 181.4 0.0 2.6e-53 180.4 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 CCC70019.1 - 1.2e-26 93.0 0.1 2.6e-26 91.8 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCC70019.1 - 3e-20 72.2 0.0 1.1e-19 70.3 0.0 2.1 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 CCC70019.1 - 6.2e-18 64.2 0.1 1.5e-17 62.9 0.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CCC70019.1 - 9.9e-09 34.3 0.0 0.0068 15.1 0.0 3.0 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CCC70019.1 - 1.1e-08 35.0 0.0 2.8e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCC70019.1 - 0.00074 18.9 0.0 0.0019 17.6 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 CCC70019.1 - 0.005 16.4 0.0 0.21 11.2 0.0 2.6 2 0 0 2 2 2 1 Biotin-lipoyl like ATP-grasp_3 PF02655.9 CCC70019.1 - 0.01 15.7 0.0 0.042 13.7 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain Peptidase_S8 PF00082.17 CCC70020.1 - 2.7e-43 148.1 0.6 3.8e-43 147.6 0.4 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CCC70020.1 - 2.6e-07 31.1 0.0 7.3e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I9 ADH_zinc_N PF00107.21 CCC70021.1 - 1.8e-12 46.9 0.0 3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCC70021.1 - 0.0038 16.9 0.2 0.12 12.0 0.1 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain WBS_methylT PF12589.3 CCC70022.1 - 5.7e-18 65.1 6.8 1.2e-17 64.1 4.7 1.6 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 CCC70022.1 - 1.8e-12 47.5 0.0 3.6e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC70022.1 - 1.7e-08 34.1 0.0 3.2e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC70022.1 - 2e-07 30.8 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC70022.1 - 6.4e-07 29.6 0.0 1.7e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCC70022.1 - 1.5e-06 28.6 0.0 6.2e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC70022.1 - 1e-05 26.0 0.0 2.5e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCC70022.1 - 5.6e-05 23.1 0.0 0.00013 22.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 CCC70022.1 - 0.00034 20.0 0.0 0.00054 19.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PCMT PF01135.14 CCC70022.1 - 0.0013 18.3 0.0 0.0027 17.2 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 CCC70022.1 - 0.0017 17.4 0.0 0.0053 15.8 0.0 1.7 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 CCC70022.1 - 0.022 13.8 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) AdoMet_MTase PF07757.8 CCC70022.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase MBOAT PF03062.14 CCC70023.1 - 1.8e-45 155.4 38.8 3.6e-37 128.2 14.3 2.5 2 1 0 2 2 2 2 MBOAT, membrane-bound O-acyltransferase family Ank_5 PF13857.1 CCC70024.1 - 2.6e-16 59.2 0.3 2e-13 50.0 0.1 3.2 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 CCC70024.1 - 5.1e-11 42.7 0.0 2.1e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCC70024.1 - 6e-11 42.5 0.7 5.7e-07 29.8 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CCC70024.1 - 1.5e-09 37.1 0.8 6.8e-07 28.7 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 CCC70024.1 - 6.7e-07 28.9 0.3 0.00023 21.1 0.1 3.3 3 0 0 3 3 3 1 Ankyrin repeat DUF1682 PF07946.9 CCC70025.1 - 1.3e-74 250.9 8.7 1.6e-74 250.6 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) HCV_NS4b PF01001.14 CCC70025.1 - 0.089 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4b ACCA PF03255.9 CCC70026.1 - 0.13 11.8 0.6 3.1 7.3 0.0 2.8 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3439 PF11921.3 CCC70026.1 - 7.2 6.3 6.1 0.51 10.1 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Thr_synth_N PF14821.1 CCC70027.1 - 1.5e-28 98.6 0.0 5.4e-28 96.8 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 CCC70027.1 - 1e-18 67.6 0.0 1.7e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Atx10homo_assoc PF09759.4 CCC70028.1 - 2.4e-36 123.5 1.9 3.5e-36 123.0 0.3 2.1 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain WD40 PF00400.27 CCC70029.1 - 1.2e-61 202.5 9.0 2.9e-13 49.1 0.1 12.8 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 CCC70029.1 - 1.4e-27 95.8 0.0 2.3e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 CCC70029.1 - 9.7e-10 38.4 3.1 0.00086 19.0 0.0 5.3 4 1 2 6 6 6 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCC70029.1 - 6.4e-05 21.2 8.6 0.32 9.0 0.2 4.8 2 2 3 5 5 5 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 CCC70029.1 - 0.0011 18.5 0.8 0.064 12.7 0.3 3.2 2 1 1 3 3 3 1 PQQ-like domain SGL PF08450.7 CCC70029.1 - 0.004 16.5 0.4 2.1 7.6 0.0 4.0 3 1 1 4 4 4 1 SMP-30/Gluconolaconase/LRE-like region Apc4_WD40 PF12894.2 CCC70029.1 - 0.04 13.4 0.0 15 5.2 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.10 CCC70029.1 - 0.06 12.4 0.3 2.4 7.1 0.0 3.1 2 1 2 4 4 4 0 CPSF A subunit region Proteasome_A_N PF10584.4 CCC70029.1 - 0.11 11.8 2.4 2.5 7.4 0.2 3.4 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Utp13 PF08625.6 CCC70029.1 - 0.13 11.9 0.1 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain UPF0029 PF01205.14 CCC70030.1 - 2.8e-32 110.6 0.1 4.7e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 CCC70030.1 - 1.6e-11 44.1 0.1 3.6e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 RWD domain TPR_11 PF13414.1 CCC70031.1 - 3.7e-11 42.5 0.0 5.5e-11 41.9 0.0 1.2 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 CCC70031.1 - 8.1e-07 28.4 0.0 0.021 14.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCC70031.1 - 4.8e-05 23.6 0.0 6.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCC70031.1 - 0.00011 21.6 0.0 0.035 13.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCC70031.1 - 0.0076 16.1 0.0 0.055 13.3 0.0 2.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat 4HB_MCP_1 PF12729.2 CCC70031.1 - 0.009 15.3 0.1 0.015 14.6 0.1 1.3 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction TPR_16 PF13432.1 CCC70031.1 - 0.032 14.9 0.0 3.8 8.3 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCC70031.1 - 0.086 12.7 0.1 13 5.8 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat Ytp1 PF10355.4 CCC70032.1 - 1.5e-109 365.3 10.0 2.2e-109 364.8 7.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 CCC70032.1 - 3.6e-23 81.1 10.4 3.6e-23 81.1 7.2 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) G10 PF01125.12 CCC70033.1 - 1.3e-59 199.8 7.1 1.5e-59 199.7 4.9 1.0 1 0 0 1 1 1 1 G10 protein Fork_head PF00250.13 CCC70034.1 - 3.1e-35 120.0 0.3 7.2e-35 118.9 0.2 1.6 1 0 0 1 1 1 1 Fork head domain zf-C3HC4 PF00097.20 CCC70035.1 - 4e-10 39.1 11.5 4e-10 39.1 8.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC70035.1 - 3.5e-09 36.5 15.2 2.5e-08 33.7 8.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCC70035.1 - 1.1e-07 31.5 15.6 6.1e-07 29.1 7.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 CCC70035.1 - 4.4e-07 29.4 11.8 1.9e-06 27.4 4.9 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC70035.1 - 8.8e-07 28.5 16.7 3.1e-06 26.7 6.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 CCC70035.1 - 1.1e-06 28.2 4.7 1.1e-06 28.2 3.2 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 CCC70035.1 - 1.9e-06 27.6 15.2 2.1e-06 27.4 7.6 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 CCC70035.1 - 3.4e-05 23.8 6.8 0.00024 21.1 2.6 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger SAP PF02037.22 CCC70035.1 - 5.1e-05 22.6 0.0 0.00016 21.0 0.0 2.0 1 0 0 1 1 1 1 SAP domain U-box PF04564.10 CCC70035.1 - 0.00052 19.9 0.1 0.01 15.7 0.0 2.9 3 0 0 3 3 2 1 U-box domain zf-RING_UBOX PF13445.1 CCC70035.1 - 0.0013 18.4 8.3 0.0013 18.4 5.8 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 CCC70035.1 - 0.043 13.3 7.3 0.16 11.5 1.3 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 CCC70035.1 - 0.1 12.1 8.1 0.053 13.0 1.9 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Mob_synth_C PF06463.8 CCC70035.1 - 0.34 10.6 4.3 0.39 10.4 1.3 2.3 2 0 0 2 2 2 0 Molybdenum Cofactor Synthesis C zf-MIZ PF02891.15 CCC70035.1 - 0.54 9.8 13.6 5.8 6.5 6.3 2.6 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger zf-Apc11 PF12861.2 CCC70035.1 - 0.85 9.5 6.0 0.75 9.6 1.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 CCC70035.1 - 5.3 6.6 15.5 0.41 10.1 4.8 3.0 2 1 2 4 4 4 0 Zinc-finger of the MIZ type in Nse subunit Stap_Strp_toxin PF01123.15 CCC70035.1 - 7.3 7.1 7.5 1.5 9.3 0.8 2.9 3 0 0 3 3 3 0 Staphylococcal/Streptococcal toxin, OB-fold domain WD40 PF00400.27 CCC70036.1 - 4.7e-05 23.0 0.1 0.13 12.1 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat PDR_assoc PF08370.6 CCC70036.1 - 0.21 11.1 0.7 0.44 10.0 0.5 1.5 1 0 0 1 1 1 0 Plant PDR ABC transporter associated Dimer_Tnp_hAT PF05699.9 CCC70037.1 - 1.4e-08 34.1 0.2 4.8e-08 32.5 0.2 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 CCC70037.1 - 0.011 15.4 2.2 0.025 14.3 1.5 1.6 1 0 0 1 1 1 0 BED zinc finger zinc_ribbon_5 PF13719.1 CCC70037.1 - 0.019 14.5 0.3 0.041 13.4 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CCC70037.1 - 0.074 12.7 0.8 0.18 11.5 0.5 1.6 1 0 0 1 1 1 0 zinc-ribbon domain Terminase_GpA PF05876.7 CCC70037.1 - 0.16 10.2 0.1 0.23 9.7 0.1 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Lipase_3 PF01764.20 CCC70038.1 - 9e-09 35.0 0.0 2.1e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 CCC70038.1 - 0.022 14.6 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCC70038.1 - 0.033 13.9 0.0 0.062 13.0 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Pro_isomerase PF00160.16 CCC70039.1 - 3.7e-23 82.4 0.0 5.3e-23 81.9 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Img2 PF05046.9 CCC70040.1 - 1.8e-27 95.3 0.1 2.7e-27 94.8 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 CCC70040.1 - 0.049 13.4 0.9 0.36 10.6 0.6 2.1 1 1 0 1 1 1 0 Translation initiation factor SUI1 Pkinase PF00069.20 CCC70041.1 - 5.5e-63 212.5 0.0 1.3e-62 211.2 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC70041.1 - 3.6e-37 127.8 0.1 2.3e-36 125.1 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC70041.1 - 2.2e-06 26.8 0.0 1.7e-05 23.9 0.0 2.4 2 1 0 2 2 2 1 Kinase-like Chordopox_A30L PF06015.7 CCC70041.1 - 0.0062 16.1 2.3 0.045 13.3 0.0 3.3 3 0 0 3 3 3 1 Chordopoxvirus A30L protein APH PF01636.18 CCC70041.1 - 0.084 12.5 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.27 CCC70042.1 - 5.1e-86 279.7 31.2 1.3e-13 50.2 0.1 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 CCC70042.1 - 1.3e-08 34.7 0.6 0.00014 21.5 0.0 3.9 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A NLE PF08154.7 CCC70042.1 - 2.9e-08 33.5 0.0 5.3e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 CCC70042.1 - 3.5e-07 28.7 13.4 0.13 10.3 0.3 5.6 4 2 2 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCC70042.1 - 0.00024 19.9 0.8 2.1 6.9 0.0 3.4 2 1 1 3 3 3 2 Nup133 N terminal like Nbas_N PF15492.1 CCC70042.1 - 0.0064 15.6 0.6 0.75 8.8 0.1 2.7 2 1 1 3 3 3 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 CCC70042.1 - 0.01 14.1 0.1 0.13 10.5 0.0 2.6 3 1 0 3 3 3 0 Cytochrome D1 heme domain Gmad1 PF10647.4 CCC70042.1 - 0.022 14.1 0.0 0.059 12.7 0.0 1.7 1 0 0 1 1 1 0 Lipoprotein LpqB beta-propeller domain Apc4_WD40 PF12894.2 CCC70042.1 - 0.096 12.2 0.1 0.79 9.2 0.0 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Glucosamine_iso PF01182.15 CCC70043.1 - 5e-46 156.9 0.0 6.7e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF515 PF04415.7 CCC70043.1 - 2.2 6.4 8.4 3 5.9 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SR-25 PF10500.4 CCC70043.1 - 7.7 5.9 10.7 13 5.1 7.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PQ-loop PF04193.9 CCC70044.1 - 3.6e-22 77.6 15.6 9.5e-12 44.2 0.2 3.5 2 1 1 3 3 3 2 PQ loop repeat DUF3215 PF11503.3 CCC70045.1 - 8.9e-17 60.4 0.0 1e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3215) PI31_Prot_C PF08577.6 CCC70046.1 - 5.7e-13 49.3 11.0 5.7e-13 49.3 7.6 2.0 2 0 0 2 2 2 1 PI31 proteasome regulator DUF2665 PF11654.3 CCC70047.1 - 8.7e-17 60.4 0.3 8.7e-17 60.4 0.2 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2665) Y_phosphatase2 PF03162.8 CCC70048.1 - 6.1e-36 123.2 2.2 4.9e-24 84.5 0.5 2.5 1 1 1 2 2 2 2 Tyrosine phosphatase family DNA_pol3_delta2 PF13177.1 CCC70048.1 - 0.13 11.8 10.0 0.019 14.6 3.8 1.8 2 0 0 2 2 2 0 DNA polymerase III, delta subunit CDC50 PF03381.10 CCC70049.1 - 5.6e-95 317.6 0.3 6.7e-95 317.4 0.2 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Not1 PF04054.10 CCC70050.1 - 5.1e-135 450.1 9.0 5.1e-135 450.1 6.2 2.8 3 0 0 3 3 3 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 CCC70050.1 - 6.7e-38 129.6 2.3 6.7e-38 129.6 1.6 3.1 4 0 0 4 4 4 1 Domain of unknown function (DUF3819) MutS_V PF00488.16 CCC70051.1 - 7.4e-74 248.0 0.0 1.5e-73 247.1 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 CCC70051.1 - 1.4e-38 132.7 2.4 2e-38 132.2 0.8 1.9 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 CCC70051.1 - 3.8e-28 97.7 0.1 1e-27 96.4 0.1 1.8 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 CCC70051.1 - 8.6e-11 41.8 2.0 2.2e-10 40.5 0.2 2.7 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 CCC70051.1 - 1.9e-05 24.7 1.2 0.00012 22.1 0.1 2.9 3 0 0 3 3 3 1 MutS domain II Baculo_PEP_C PF04513.7 CCC70051.1 - 0.69 9.7 9.5 3.2 7.5 0.0 4.4 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pkinase PF00069.20 CCC70052.1 - 1.6e-72 243.7 0.2 3.4e-72 242.7 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC70052.1 - 1.5e-31 109.4 0.0 5.2e-21 74.8 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCC70052.1 - 8.6e-08 31.4 0.5 1.1e-05 24.5 0.1 3.1 1 1 1 2 2 2 1 Kinase-like MCR_beta PF02241.13 CCC70052.1 - 0.16 11.1 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain DUF866 PF05907.8 CCC70053.1 - 4.3e-27 94.5 8.4 2.9e-15 56.1 0.2 2.0 1 1 1 2 2 2 2 Eukaryotic protein of unknown function (DUF866) GFA PF04828.9 CCC70053.1 - 0.2 11.5 1.7 0.51 10.3 0.2 2.3 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DUF581 PF04570.9 CCC70053.1 - 5 6.4 7.2 0.25 10.6 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF581) Flocculin_t3 PF13928.1 CCC70054.1 - 1.9e-12 47.1 76.9 2e-06 27.8 9.6 22.2 14 4 6 20 20 20 4 Flocculin type 3 repeat MRP-S31 PF15433.1 CCC70054.1 - 7.2 5.9 8.0 0.38 10.1 1.5 1.8 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 Cofilin_ADF PF00241.15 CCC70055.1 - 2.2e-24 85.7 0.0 6.1e-24 84.3 0.0 1.8 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.23 CCC70055.1 - 6.2e-16 57.5 0.7 6.2e-16 57.5 0.5 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 CCC70055.1 - 2.1e-15 56.0 0.3 7.8e-15 54.1 0.2 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 CCC70055.1 - 3.7e-06 26.3 0.0 8.1e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Glyco_hydro_16 PF00722.16 CCC70056.1 - 9.2e-20 70.6 3.5 2e-19 69.5 2.5 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 zf-LYAR PF08790.6 CCC70057.1 - 2.5e-15 55.8 7.6 5.4e-15 54.7 5.3 1.6 1 0 0 1 1 1 1 LYAR-type C2HC zinc finger DUF2072 PF09845.4 CCC70057.1 - 0.015 15.2 7.8 0.021 14.7 5.4 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) zf-TRAF PF02176.13 CCC70057.1 - 0.11 12.9 3.0 0.21 12.0 2.1 1.6 1 0 0 1 1 1 0 TRAF-type zinc finger DUF3306 PF11748.3 CCC70057.1 - 0.12 13.0 5.9 0.17 12.5 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) DUF4557 PF15101.1 CCC70057.1 - 0.13 12.0 7.1 0.16 11.8 4.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF2201_N PF13203.1 CCC70057.1 - 0.17 11.0 6.1 0.19 10.8 4.2 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain zf-C2H2_jaz PF12171.3 CCC70057.1 - 0.2 11.8 5.5 0.27 11.4 0.4 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-GRF PF06839.7 CCC70057.1 - 0.34 10.8 4.3 1.5 8.8 3.0 2.2 1 0 0 1 1 1 0 GRF zinc finger Gemini_AL2 PF01440.11 CCC70057.1 - 0.4 10.7 11.3 6.1 6.9 7.8 2.2 1 1 0 1 1 1 0 Geminivirus AL2 protein XPA_N PF01286.13 CCC70057.1 - 0.43 10.2 5.4 1.9 8.2 0.2 2.3 2 0 0 2 2 2 0 XPA protein N-terminal Ycf1 PF05758.7 CCC70057.1 - 1.1 6.8 13.2 1.2 6.7 9.1 1.0 1 0 0 1 1 1 0 Ycf1 zf-C2H2 PF00096.21 CCC70057.1 - 1.2 9.5 6.3 0.66 10.4 0.7 2.6 1 1 1 2 2 2 0 Zinc finger, C2H2 type A2L_zn_ribbon PF08792.5 CCC70057.1 - 1.2 8.6 8.7 0.28 10.6 0.5 3.1 1 1 1 2 2 2 0 A2L zinc ribbon domain zf-C2H2_4 PF13894.1 CCC70057.1 - 1.5 9.3 4.2 1.2e+02 3.3 2.9 2.5 1 1 0 1 1 1 0 C2H2-type zinc finger Neur_chan_memb PF02932.11 CCC70057.1 - 1.7 8.4 5.6 2.1 8.1 3.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region zf-met PF12874.2 CCC70057.1 - 1.9 8.8 5.5 12 6.2 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 CCC70057.1 - 2.1 8.3 6.2 1.1 9.3 1.0 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger RNHCP PF12647.2 CCC70057.1 - 2.2 8.1 7.2 4.3 7.2 2.8 2.5 1 1 1 3 3 3 0 RNHCP domain FHIPEP PF00771.15 CCC70057.1 - 3 6.0 6.2 3.5 5.8 4.3 1.1 1 0 0 1 1 1 0 FHIPEP family C1_4 PF07975.7 CCC70057.1 - 5 7.2 9.9 1.1 9.3 3.4 2.5 1 1 1 2 2 2 0 TFIIH C1-like domain Ndc1_Nup PF09531.5 CCC70057.1 - 9.7 4.4 6.9 11 4.2 4.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Csm1 PF12539.3 CCC70058.1 - 2.6e-33 114.3 0.1 2.6e-33 114.3 0.1 1.6 2 0 0 2 2 2 1 Chromosome segregation protein Csm1/Pcs1 Rota_NSP4 PF01452.11 CCC70058.1 - 0.002 17.5 0.7 0.0034 16.7 0.5 1.4 1 0 0 1 1 1 1 Rotavirus non structural protein Complex1_49kDa PF00346.14 CCC70058.1 - 0.1 11.5 0.1 0.19 10.6 0.0 1.5 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit IncA PF04156.9 CCC70058.1 - 0.16 11.5 10.7 0.087 12.4 5.7 1.6 2 0 0 2 2 2 0 IncA protein Syntaxin-6_N PF09177.6 CCC70058.1 - 0.19 12.1 2.2 0.47 10.8 1.5 1.7 1 0 0 1 1 1 0 Syntaxin 6, N-terminal Phage_GP20 PF06810.6 CCC70058.1 - 1.3 8.4 7.7 2.7 7.4 5.4 1.5 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF972 PF06156.8 CCC70058.1 - 1.9 8.8 6.2 1.1 9.6 2.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF3450 PF11932.3 CCC70058.1 - 2.7 7.1 9.4 0.55 9.4 4.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) ADIP PF11559.3 CCC70058.1 - 5.7 6.8 11.6 2.4 8.0 6.2 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding WD40 PF00400.27 CCC70059.1 - 1.5e-68 224.3 12.5 5.1e-11 42.0 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 CCC70059.1 - 4.8e-27 93.9 13.2 8.1e-27 93.2 9.2 1.4 1 0 0 1 1 1 1 Tup N-terminal Nup160 PF11715.3 CCC70059.1 - 2.4e-05 22.6 1.6 0.74 7.8 0.0 4.1 1 1 3 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCC70059.1 - 0.0031 16.3 2.8 0.013 14.2 0.3 2.9 2 1 0 2 2 2 1 Nup133 N terminal like FadA PF09403.5 CCC70059.1 - 0.16 11.9 6.7 0.28 11.1 4.6 1.3 1 0 0 1 1 1 0 Adhesion protein FadA Thioredoxin PF00085.15 CCC70060.1 - 1.5e-27 95.2 0.1 1.9e-27 94.9 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 CCC70060.1 - 1.8e-07 30.7 0.0 2.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 CCC70060.1 - 5.5e-07 29.7 0.3 3.1e-06 27.3 0.2 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 CCC70060.1 - 1.2e-06 28.5 0.2 9.4e-06 25.6 0.1 2.2 1 1 1 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 CCC70060.1 - 0.00022 20.8 0.1 0.00043 19.9 0.1 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCC70060.1 - 0.00086 18.8 0.1 0.0082 15.6 0.1 1.9 1 1 1 2 2 2 1 Redoxin TraF PF13728.1 CCC70060.1 - 0.0027 17.2 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.1 CCC70060.1 - 0.0033 17.2 0.1 0.0059 16.3 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin domain HyaE PF07449.6 CCC70060.1 - 0.0043 16.9 0.0 0.0073 16.1 0.0 1.3 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE TrbC_Ftype PF09673.5 CCC70060.1 - 0.032 13.8 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Phosducin PF02114.11 CCC70060.1 - 0.061 12.0 0.0 0.066 11.9 0.0 1.1 1 0 0 1 1 1 0 Phosducin KaiB PF07689.7 CCC70060.1 - 0.073 12.5 0.0 0.16 11.4 0.0 1.6 1 1 0 1 1 1 0 KaiB domain DUF953 PF06110.6 CCC70060.1 - 0.081 12.3 0.4 0.16 11.4 0.3 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) RE_Eco29kI PF09517.5 CCC70060.1 - 0.11 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Eco29kI restriction endonuclease DSBA PF01323.15 CCC70060.1 - 0.13 11.8 0.3 4.6 6.7 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Lipoprotein_7 PF01540.11 CCC70061.1 - 0.068 12.2 0.1 0.077 12.0 0.1 1.1 1 0 0 1 1 1 0 Adhesin lipoprotein Med12 PF09497.5 CCC70062.1 - 1.1e-23 82.9 0.2 2.7e-23 81.7 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 PP2C PF00481.16 CCC70063.1 - 4.2e-30 104.9 0.0 5.8e-29 101.2 0.0 2.4 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 CCC70063.1 - 0.022 14.1 0.0 0.077 12.3 0.0 1.8 1 1 0 1 1 1 0 Protein phosphatase 2C P34-Arc PF04045.9 CCC70064.1 - 8.2e-94 313.4 0.8 1e-93 313.0 0.5 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF1132 PF06575.7 CCC70064.1 - 0.033 14.4 0.1 0.088 13.0 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) PAT1 PF09770.4 CCC70065.1 - 2e-234 780.4 70.2 4.1e-207 690.1 20.3 2.0 1 1 1 2 2 2 2 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 CCC70065.1 - 1.5 8.6 50.1 0.089 12.6 26.7 2.4 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Epimerase PF01370.16 CCC70066.1 - 1.8e-18 66.8 0.0 2.5e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCC70066.1 - 1.6e-10 41.2 0.0 3.5e-10 40.1 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 CCC70066.1 - 1.8e-08 33.4 0.0 2.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCC70066.1 - 7.7e-08 31.5 0.0 1.9e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 CCC70066.1 - 1.4e-05 25.0 0.2 2.8e-05 24.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 CCC70066.1 - 2.2e-05 24.1 0.0 3.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 CCC70066.1 - 0.0049 15.8 0.0 0.12 11.2 0.1 2.3 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 CCC70066.1 - 0.0088 15.3 0.0 0.041 13.1 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family DXP_redisom_C PF08436.7 CCC70066.1 - 0.019 14.8 0.1 0.18 11.7 0.0 2.3 1 1 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal Zn_clus PF00172.13 CCC70067.1 - 2.3e-08 33.7 9.5 5.3e-08 32.6 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 CCC70067.1 - 0.00023 20.1 3.0 0.00023 20.1 2.0 2.4 2 1 0 2 2 2 1 Fungal specific transcription factor domain MFS_1 PF07690.11 CCC70068.1 - 3.2e-18 65.5 22.3 3.2e-18 65.5 15.4 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3353 PF11833.3 CCC70068.1 - 5.9 6.2 6.9 1.8 7.9 0.3 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3353) Ureidogly_hydro PF04115.7 CCC70069.1 - 2.5e-44 150.5 0.0 3.1e-44 150.2 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Malate_synthase PF01274.17 CCC70070.1 - 7.3e-217 720.5 0.0 8.7e-217 720.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DUF1870 PF08965.5 CCC70070.1 - 0.049 13.2 0.0 3.7 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1870) Asp_Glu_race PF01177.17 CCC70071.1 - 2.9e-17 63.3 0.0 3.4e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Peptidase_C3 PF00548.15 CCC70071.1 - 0.02 14.7 0.1 0.031 14.0 0.0 1.2 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Amidohydro_1 PF01979.15 CCC70072.1 - 2.7e-32 112.7 0.0 6.8e-32 111.4 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 CCC70072.1 - 7.6e-28 98.3 0.0 2.6e-16 60.4 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 CCC70072.1 - 2.1e-08 33.7 0.1 1.8e-05 24.1 0.0 2.4 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 CCC70072.1 - 6.2e-08 32.3 0.2 1.6e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase Transp_cyt_pur PF02133.10 CCC70073.1 - 5.7e-178 591.9 38.4 6.6e-178 591.7 26.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Allantoicase PF03561.10 CCC70074.1 - 2.7e-94 312.6 1.2 2.2e-50 170.0 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat S-methyl_trans PF02574.11 CCC70075.1 - 4.1e-96 321.8 0.0 4.7e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Kelch_1 PF01344.20 CCC70075.1 - 0.026 14.0 0.2 0.33 10.5 0.0 2.5 2 0 0 2 2 2 0 Kelch motif PEP_mutase PF13714.1 CCC70075.1 - 0.18 11.0 0.0 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Flo11 PF10182.4 CCC70076.1 - 5.6e-33 113.6 0.3 6.8e-33 113.3 0.2 1.1 1 0 0 1 1 1 1 Flo11 domain FMN_dh PF01070.13 CCC70077.1 - 3.6e-114 381.3 0.0 4.2e-114 381.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 CCC70077.1 - 2.2e-07 30.1 0.0 3.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase NMO PF03060.10 CCC70077.1 - 0.0053 15.9 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 CCC70077.1 - 0.051 12.4 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 CCC70077.1 - 0.077 12.0 0.0 11 5.0 0.0 2.7 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 CCC70077.1 - 0.099 11.8 0.1 3 7.0 0.0 2.6 3 0 0 3 3 3 0 Histidine biosynthesis protein MFS_1 PF07690.11 CCC70078.1 - 1.8e-22 79.5 11.7 5.4e-22 77.9 7.7 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sir1 PF11603.3 CCC70079.1 - 1.9e-05 24.8 0.0 3.1e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Regulatory protein Sir1 Sir1 PF11603.3 CCC70082.1 - 4.5e-05 23.5 0.0 8.6e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Regulatory protein Sir1 Pex2_Pex12 PF04757.9 CCC70084.1 - 1.2e-14 54.2 7.5 3.5e-14 52.7 5.2 1.7 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 CCC70084.1 - 0.0044 16.6 15.6 0.0091 15.6 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Peptidase_C21 PF05381.7 CCC70084.1 - 0.093 12.8 0.1 0.35 10.9 0.0 1.9 2 0 0 2 2 2 0 Tymovirus endopeptidase zf-C3HC4_2 PF13923.1 CCC70084.1 - 0.72 9.9 20.7 0.73 9.9 13.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Sugar_tr PF00083.19 CCC70086.1 - 5e-163 542.8 33.6 5.7e-163 542.6 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC70086.1 - 5.8e-34 117.3 44.0 2.1e-29 102.3 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCC70086.1 - 0.00014 20.2 2.0 0.00024 19.4 0.8 1.8 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-C2H2 PF00096.21 CCC70087.1 - 5.2e-09 35.9 28.1 0.0023 18.1 0.5 5.3 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC70087.1 - 1.4e-07 31.4 7.1 0.00024 21.2 0.2 5.0 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCC70087.1 - 0.00029 20.8 0.5 0.00029 20.8 0.4 3.3 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 CCC70087.1 - 0.00088 19.4 30.4 0.16 12.3 0.3 4.6 5 0 0 5 5 5 3 C2H2-type zinc finger zf-C2H2_2 PF12756.2 CCC70087.1 - 0.016 15.3 3.2 0.42 10.7 0.8 2.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RNA_pol_Rpb2_2 PF04561.9 CCC70087.1 - 0.05 13.0 0.1 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase Rpb2, domain 2 zf-met PF12874.2 CCC70087.1 - 0.099 12.8 0.4 0.099 12.8 0.3 4.7 5 0 0 5 5 5 0 Zinc-finger of C2H2 type Hexokinase_2 PF03727.11 CCC70088.1 - 8e-94 313.3 0.0 1.2e-93 312.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCC70088.1 - 9.6e-85 283.0 0.0 1.3e-84 282.6 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 CCC70088.1 - 0.089 12.0 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain Ppx-GppA PF02541.11 CCC70089.1 - 1.7e-64 217.8 0.0 2.2e-64 217.3 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Sec63 PF02889.11 CCC70090.1 - 8e-47 159.9 0.6 1.3e-46 159.3 0.4 1.3 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 CCC70090.1 - 1e-27 96.7 0.0 3.2e-27 95.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 CCC70090.1 - 1.7e-11 44.2 0.1 4.1e-11 43.0 0.1 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCC70090.1 - 3.3e-11 42.8 0.0 9.1e-11 41.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 CCC70090.1 - 0.00067 19.8 0.4 0.0053 16.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain UvrD-helicase PF00580.16 CCC70090.1 - 0.088 12.0 2.0 0.27 10.4 0.0 2.5 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain T2SE PF00437.15 CCC70090.1 - 0.09 11.6 0.0 0.21 10.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2420 PF10336.4 CCC70091.1 - 7.1e-34 115.8 0.4 1.1e-33 115.1 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) PDEase_II PF02112.10 CCC70093.1 - 4.5e-60 203.3 0.8 6.4e-60 202.8 0.5 1.2 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 CCC70093.1 - 0.00011 21.8 0.0 0.00018 21.1 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF1765 PF08578.5 CCC70093.1 - 0.027 14.5 0.0 0.068 13.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) RAI1 PF08652.6 CCC70094.1 - 1.1e-26 92.3 0.1 2.6e-26 91.2 0.1 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease SecB PF02556.9 CCC70094.1 - 0.086 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Preprotein translocase subunit SecB tRNA-synt_1c PF00749.16 CCC70095.1 - 1.4e-117 391.8 0.1 1.9e-117 391.4 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 CCC70095.1 - 7.1e-38 129.9 0.8 9.6e-37 126.3 0.1 2.5 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 CCC70095.1 - 4e-06 27.2 0.0 1.2e-05 25.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCC70095.1 - 0.0017 18.2 0.0 0.0068 16.3 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCC70095.1 - 0.0032 17.3 0.0 0.0086 15.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 CCC70095.1 - 0.2 10.7 2.6 0.13 11.3 0.1 1.9 2 1 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Plus-3 PF03126.13 CCC70096.1 - 3.9e-33 113.7 0.1 1.5e-32 111.8 0.0 2.1 1 0 0 1 1 1 1 Plus-3 domain A_deamin PF02137.13 CCC70097.1 - 1.4e-61 208.6 0.1 1.8e-61 208.3 0.1 1.1 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain UPF0150 PF03681.10 CCC70097.1 - 0.055 13.0 0.0 0.093 12.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) APC10 PF03256.11 CCC70098.1 - 6.3e-52 175.9 0.0 7.7e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 CCC70098.1 - 5.9e-07 29.3 0.0 9.1e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain Cse1 PF08506.5 CCC70099.1 - 2.6e-168 559.3 7.5 4.4e-168 558.5 5.2 1.4 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 CCC70099.1 - 5e-106 354.5 6.8 9e-106 353.7 2.8 2.3 2 0 0 2 2 2 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 CCC70099.1 - 4.7e-16 58.4 0.2 1.8e-14 53.3 0.0 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 CCC70099.1 - 0.0016 18.3 2.2 0.034 14.0 0.0 3.9 3 1 0 3 3 3 1 Exportin 1-like protein HEAT_EZ PF13513.1 CCC70099.1 - 0.053 14.0 0.8 36 5.0 0.0 4.6 5 0 0 5 5 5 0 HEAT-like repeat CBFB_NFYA PF02045.10 CCC70100.1 - 6.6e-28 97.0 7.7 1.5e-27 95.8 5.3 1.7 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B GIDA PF01134.17 CCC70101.1 - 4.5e-156 519.6 0.0 5.8e-156 519.2 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 CCC70101.1 - 3.3e-21 75.1 0.3 1e-20 73.5 0.2 1.9 1 0 0 1 1 1 1 GidA associated domain 3 DAO PF01266.19 CCC70101.1 - 4.6e-07 29.0 0.9 0.00069 18.6 0.0 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCC70101.1 - 1.4e-06 28.3 0.3 3.9e-06 26.8 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCC70101.1 - 6.7e-05 22.1 0.1 0.00011 21.4 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCC70101.1 - 0.00015 20.7 0.9 0.0018 17.1 0.3 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 CCC70101.1 - 0.033 14.5 0.1 0.11 12.9 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCC70101.1 - 0.1 11.0 0.9 0.91 7.9 0.2 2.2 2 0 0 2 2 2 0 HI0933-like protein GARS_A PF01071.14 CCC70102.1 - 8.2e-82 273.4 0.0 1.5e-81 272.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 CCC70102.1 - 5.2e-34 116.7 0.0 3.1e-33 114.2 0.0 2.4 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 CCC70102.1 - 1.2e-30 106.5 0.0 2.8e-30 105.3 0.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 CCC70102.1 - 2.3e-27 94.9 0.1 6e-27 93.6 0.1 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 CCC70102.1 - 7e-17 61.4 1.1 3.3e-16 59.2 0.6 2.3 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 CCC70102.1 - 3.3e-12 46.5 0.0 1.2e-11 44.6 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCC70102.1 - 1.5e-10 40.3 0.0 3.7e-10 39.0 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 CCC70102.1 - 4.5e-07 29.8 0.1 1.5e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 CCC70102.1 - 1.1e-06 28.0 0.0 2.2e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CCC70102.1 - 0.00087 18.6 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 CCC70102.1 - 0.049 13.0 0.0 0.15 11.5 0.0 1.8 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Sec15 PF04091.7 CCC70103.1 - 1.2e-100 336.8 7.8 1.2e-100 336.8 5.4 2.4 2 1 1 3 3 3 1 Exocyst complex subunit Sec15-like THUMP PF02926.12 CCC70104.1 - 4.6e-27 94.6 0.9 4.6e-27 94.6 0.6 1.6 2 0 0 2 2 2 1 THUMP domain DUF1077 PF06417.7 CCC70105.1 - 4e-43 145.7 6.5 5.2e-43 145.3 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) CDC50 PF03381.10 CCC70106.1 - 0.012 14.7 0.4 0.018 14.2 0.2 1.2 1 0 0 1 1 1 0 LEM3 (ligand-effect modulator 3) family / CDC50 family Herpes_UL17 PF04559.7 CCC70106.1 - 0.058 11.9 0.0 0.069 11.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL17 protein RAI1 PF08652.6 CCC70106.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease SAPS PF04499.10 CCC70107.1 - 6.3e-147 490.0 16.5 6.3e-147 490.0 11.4 1.7 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein ADK_lid PF05191.9 CCC70108.1 - 0.092 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid SPRY PF00622.23 CCC70109.1 - 1.4e-19 70.3 0.0 4.8e-19 68.6 0.0 1.9 1 1 0 1 1 1 1 SPRY domain CLTH PF10607.4 CCC70109.1 - 2.9e-13 49.7 2.2 6.2e-13 48.6 1.5 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 CCC70109.1 - 0.013 15.2 0.1 0.034 13.9 0.0 1.8 1 0 0 1 1 1 0 LisH Nop14 PF04147.7 CCC70109.1 - 5.8 4.7 18.7 0.29 8.9 3.6 2.1 2 0 0 2 2 2 0 Nop14-like family CD20 PF04103.10 CCC70110.1 - 0.00059 19.7 2.2 0.00066 19.6 1.6 1.1 1 0 0 1 1 1 1 CD20-like family UPF0197 PF05251.7 CCC70110.1 - 0.037 14.3 2.6 0.044 14.0 1.8 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0197) DUF2628 PF10947.3 CCC70110.1 - 0.048 13.4 1.0 0.06 13.1 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) DUF939 PF06081.6 CCC70110.1 - 0.054 13.3 1.5 0.059 13.2 1.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF939) VIT1 PF01988.14 CCC70110.1 - 0.1 12.1 3.5 0.11 11.9 2.1 1.3 1 1 0 1 1 1 0 VIT family Sulf_transp PF04143.9 CCC70110.1 - 0.52 10.3 3.4 1.3 9.0 0.5 2.1 2 0 0 2 2 2 0 Sulphur transport COX4 PF02936.9 CCC70111.1 - 2.4e-09 37.0 0.1 2.8e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV CytB6-F_Fe-S PF08802.5 CCC70111.1 - 0.15 12.0 0.9 0.28 11.1 0.6 1.4 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit UAA PF08449.6 CCC70112.1 - 2.3e-16 59.5 24.1 2.9e-16 59.2 16.7 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CCC70112.1 - 2.4e-09 37.0 8.7 2.4e-09 37.0 6.0 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CCC70112.1 - 0.013 15.5 32.7 0.34 10.9 7.2 2.3 2 0 0 2 2 2 0 EamA-like transporter family PHO4 PF01384.15 CCC70112.1 - 0.16 10.5 10.7 0.034 12.8 1.3 2.8 3 1 0 3 3 3 0 Phosphate transporter family Multi_Drug_Res PF00893.14 CCC70112.1 - 0.97 9.9 12.6 2.6 8.5 4.3 2.6 2 0 0 2 2 2 0 Small Multidrug Resistance protein HAD_2 PF13419.1 CCC70113.1 - 4e-20 72.7 0.0 5.1e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC70113.1 - 0.12 12.8 0.0 3.5 7.9 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Vps51 PF08700.6 CCC70114.1 - 0.083 12.7 9.6 0.042 13.6 1.9 3.5 2 1 0 3 3 3 0 Vps51/Vps67 BUD22 PF09073.5 CCC70114.1 - 4 6.3 33.0 8.8 5.2 22.8 1.5 1 0 0 1 1 1 0 BUD22 Flavodoxin_2 PF02525.12 CCC70115.1 - 2.4e-54 183.8 0.0 2.9e-54 183.6 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCC70115.1 - 1e-11 44.5 0.0 1.8e-11 43.7 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CCC70115.1 - 0.0025 17.1 0.1 0.0044 16.3 0.1 1.5 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_2 PF02525.12 CCC70116.1 - 3.9e-55 186.4 0.1 4.5e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCC70116.1 - 3.6e-12 46.0 0.0 8.3e-12 44.8 0.0 1.6 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CCC70116.1 - 0.0052 16.1 4.3 0.0065 15.8 1.1 2.5 2 2 1 3 3 3 1 Flavodoxin zf-HIT PF04438.11 CCC70117.1 - 0.00056 19.4 11.5 0.00056 19.4 8.0 1.7 2 0 0 2 2 2 1 HIT zinc finger Dor1 PF04124.7 CCC70117.1 - 0.021 13.3 0.6 0.028 12.8 0.4 1.2 1 0 0 1 1 1 0 Dor1-like family Fmp27_GFWDK PF10347.4 CCC70117.1 - 0.082 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain ABC_tran PF00005.22 CCC70118.1 - 5.4e-50 169.2 0.0 5.3e-25 88.2 0.0 2.7 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 CCC70118.1 - 1.1e-22 81.3 1.6 1.7e-06 28.2 0.0 4.3 2 2 1 3 3 3 3 AAA domain ABC_tran_2 PF12848.2 CCC70118.1 - 2.4e-20 72.1 3.7 2.4e-20 72.1 2.5 3.3 4 0 0 4 4 2 1 ABC transporter SMC_N PF02463.14 CCC70118.1 - 3.8e-10 39.3 0.3 0.39 9.9 0.0 4.4 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCC70118.1 - 6.1e-09 35.2 0.0 0.00087 18.7 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CCC70118.1 - 1e-08 35.9 0.0 0.00086 20.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCC70118.1 - 5.9e-08 32.9 0.0 0.011 15.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 CCC70118.1 - 9.4e-08 32.5 0.0 0.0042 17.5 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_18 PF13238.1 CCC70118.1 - 1.3e-07 31.9 0.0 0.0052 17.0 0.0 3.2 3 1 0 3 3 2 2 AAA domain DUF258 PF03193.11 CCC70118.1 - 2.2e-07 30.2 0.0 0.00024 20.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 CCC70118.1 - 1.1e-06 29.0 10.7 0.0021 18.4 0.0 3.8 5 0 0 5 5 3 2 AAA domain MMR_HSR1 PF01926.18 CCC70118.1 - 4.5e-06 26.5 0.4 0.034 14.1 0.2 3.5 3 2 0 3 3 3 2 50S ribosome-binding GTPase NACHT PF05729.7 CCC70118.1 - 1.4e-05 24.8 0.8 0.16 11.6 0.0 2.8 3 0 0 3 3 2 2 NACHT domain RNA_helicase PF00910.17 CCC70118.1 - 2.3e-05 24.5 0.0 0.24 11.5 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.1 CCC70118.1 - 2.8e-05 23.3 0.3 0.77 8.7 0.0 4.0 4 2 0 5 5 4 2 AAA ATPase domain AAA PF00004.24 CCC70118.1 - 4.1e-05 23.7 0.1 0.17 12.0 0.0 3.0 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 CCC70118.1 - 5.3e-05 23.2 0.0 0.3 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CCC70118.1 - 6e-05 22.9 0.0 0.18 11.6 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.1 CCC70118.1 - 9.1e-05 22.3 0.0 0.48 10.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCC70118.1 - 0.00011 22.2 0.0 0.61 10.0 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 CCC70118.1 - 0.00017 21.1 0.0 0.78 9.1 0.1 3.3 3 0 0 3 3 3 2 AAA-like domain MobB PF03205.9 CCC70118.1 - 0.00026 20.6 0.2 0.0069 16.0 0.1 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B VirE PF05272.6 CCC70118.1 - 0.00051 19.5 0.1 0.39 10.1 0.0 2.7 3 0 0 3 3 3 1 Virulence-associated protein E Arch_ATPase PF01637.13 CCC70118.1 - 0.00069 19.3 0.3 1.6 8.3 0.0 3.0 3 0 0 3 3 3 2 Archaeal ATPase Dynamin_N PF00350.18 CCC70118.1 - 0.00071 19.4 0.7 1.3 8.7 0.0 3.6 2 1 1 3 3 3 1 Dynamin family AAA_25 PF13481.1 CCC70118.1 - 0.00081 18.8 0.1 1.8 7.9 0.0 3.3 3 1 0 3 3 3 1 AAA domain MCM PF00493.18 CCC70118.1 - 0.0016 17.2 1.1 3.2 6.4 0.0 3.1 3 0 0 3 3 3 1 MCM2/3/5 family Rad17 PF03215.10 CCC70118.1 - 0.0031 16.2 0.1 1.1 7.8 0.0 2.7 3 0 0 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_5 PF07728.9 CCC70118.1 - 0.004 16.8 0.0 2.6 7.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ArgK PF03308.11 CCC70118.1 - 0.0074 15.0 0.1 2 7.0 0.0 2.8 3 0 0 3 3 3 1 ArgK protein T2SE PF00437.15 CCC70118.1 - 0.0092 14.9 0.0 0.19 10.6 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.17 CCC70118.1 - 0.0097 14.7 0.0 3.1 6.5 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain PduV-EutP PF10662.4 CCC70118.1 - 0.012 15.0 0.1 6.8 6.1 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF815 PF05673.8 CCC70118.1 - 0.015 14.2 0.0 5.3 5.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) DAP3 PF10236.4 CCC70118.1 - 0.016 14.1 0.9 5.4 5.8 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 SbcCD_C PF13558.1 CCC70118.1 - 0.018 14.9 0.6 1.5 8.7 0.0 3.4 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.12 CCC70118.1 - 0.019 14.8 1.0 14 5.3 0.0 3.4 3 1 1 4 4 4 0 Domain of unknown function DUF87 DUF2813 PF11398.3 CCC70118.1 - 0.042 12.9 0.4 3.8 6.4 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2813) NTPase_1 PF03266.10 CCC70118.1 - 0.049 13.3 0.1 1.8 8.2 0.1 2.5 2 0 0 2 2 2 0 NTPase FtsK_SpoIIIE PF01580.13 CCC70118.1 - 0.092 12.2 0.0 3.1 7.2 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family FeoB_N PF02421.13 CCC70118.1 - 0.095 11.9 0.0 2.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.15 CCC70118.1 - 0.73 8.4 5.1 2.8 6.5 0.0 2.6 3 1 0 3 3 2 0 G-protein alpha subunit SRR1 PF07985.7 CCC70119.1 - 4.7e-16 58.4 0.0 1e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 SRR1 NIF3 PF01784.13 CCC70121.1 - 2.5e-64 217.1 0.1 3e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) DUF1442 PF07279.6 CCC70121.1 - 0.05 12.6 0.1 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1442) Autophagy_act_C PF03987.10 CCC70121.1 - 0.086 13.0 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 Autophagocytosis associated protein, active-site domain SNARE PF05739.14 CCC70122.1 - 1.5e-10 40.5 5.3 1.5e-10 40.5 3.7 2.1 2 0 0 2 2 2 1 SNARE domain PX PF00787.19 CCC70122.1 - 2.9e-10 39.9 2.1 4e-10 39.4 0.2 2.1 2 0 0 2 2 2 1 PX domain SlyX PF04102.7 CCC70122.1 - 0.63 10.4 8.0 3.7 8.0 5.6 2.4 1 0 0 1 1 1 0 SlyX WD40 PF00400.27 CCC70123.1 - 3.9e-16 58.2 18.4 7.7e-08 31.9 0.2 6.5 6 1 0 6 6 6 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCC70123.1 - 0.0035 17.1 0.1 0.2 11.4 0.0 3.0 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region IKI3 PF04762.7 CCC70123.1 - 0.0079 14.0 0.0 0.012 13.4 0.0 1.2 1 0 0 1 1 1 1 IKI3 family Cyclin PF08613.6 CCC70124.1 - 0.00033 21.0 0.1 0.00069 20.0 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCC70124.1 - 0.036 13.6 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain Kinesin PF00225.18 CCC70125.1 - 6.3e-113 376.8 1.2 1.1e-112 376.0 0.8 1.5 1 1 0 1 1 1 1 Kinesin motor domain BolA PF01722.13 CCC70127.1 - 2.9e-20 72.0 0.0 3.5e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein Fucose_iso_N1 PF07881.7 CCC70127.1 - 0.086 12.3 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 L-fucose isomerase, first N-terminal domain FAD_binding_3 PF01494.14 CCC70128.1 - 7.5e-20 71.2 0.0 6.9e-09 35.2 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 CCC70128.1 - 0.00018 20.5 0.0 0.023 13.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCC70128.1 - 0.00083 18.3 0.0 0.034 13.0 0.0 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 CCC70128.1 - 0.0039 17.0 0.0 0.02 14.7 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 CCC70128.1 - 0.0094 14.8 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_3 PF13738.1 CCC70128.1 - 0.011 15.7 0.0 0.24 11.4 0.0 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 CCC70128.1 - 0.018 15.0 0.0 0.044 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 CCC70128.1 - 0.021 13.4 0.0 0.23 10.0 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 CCC70128.1 - 0.025 13.6 0.0 0.059 12.4 0.0 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 CCC70128.1 - 0.036 14.4 0.1 6 7.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCC70128.1 - 0.042 13.6 0.0 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 CCC70128.1 - 0.077 11.8 0.1 0.13 11.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 CCC70128.1 - 0.21 10.0 0.0 0.38 9.1 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein ATP_bind_3 PF01171.15 CCC70129.1 - 3.2e-19 69.1 0.0 6.6e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 CCC70129.1 - 0.00014 22.1 0.0 0.00033 20.9 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) tRNA_Me_trans PF03054.11 CCC70129.1 - 0.003 16.1 0.0 0.0056 15.2 0.0 1.4 1 1 0 1 1 1 1 tRNA methyl transferase PAPS_reduct PF01507.14 CCC70129.1 - 0.082 12.7 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family MU117 PF15474.1 CCC70129.1 - 0.44 11.0 5.1 0.12 12.9 1.0 1.9 2 0 0 2 2 2 0 Meiotically up-regulated gene family DUF2616 PF11077.3 CCC70129.1 - 4.5 6.7 7.4 0.28 10.6 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) HIPIP PF01355.12 CCC70129.1 - 7 6.8 6.7 5 7.3 0.4 2.9 3 1 0 3 3 3 0 High potential iron-sulfur protein Ras PF00071.17 CCC70130.1 - 2.1e-60 202.7 0.2 2.5e-60 202.5 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC70130.1 - 3.5e-19 69.4 0.0 5.7e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC70130.1 - 3e-13 49.3 0.0 3.9e-13 49.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCC70130.1 - 2.5e-07 30.6 0.1 3.8e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_15 PF13175.1 CCC70130.1 - 4.7e-05 22.6 0.3 5.2e-05 22.4 0.2 1.2 1 0 0 1 1 1 1 AAA ATPase domain GTP_EFTU PF00009.22 CCC70130.1 - 8e-05 22.1 0.1 0.00026 20.4 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 CCC70130.1 - 0.00084 18.5 0.3 0.0021 17.2 0.1 1.7 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 CCC70130.1 - 0.0013 17.9 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.1 CCC70130.1 - 0.002 18.1 0.3 0.02 14.8 0.2 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCC70130.1 - 0.0042 17.2 0.2 0.015 15.4 0.0 1.9 1 1 1 2 2 2 1 AAA domain PduV-EutP PF10662.4 CCC70130.1 - 0.0057 16.1 0.0 0.0095 15.4 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation KAP_NTPase PF07693.9 CCC70130.1 - 0.0088 15.0 0.0 0.012 14.6 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain SRPRB PF09439.5 CCC70130.1 - 0.013 14.6 0.1 0.029 13.5 0.0 1.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 CCC70130.1 - 0.023 13.9 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B ABC_tran PF00005.22 CCC70130.1 - 0.028 14.7 0.4 0.039 14.2 0.3 1.5 1 1 0 1 1 1 0 ABC transporter Septin PF00735.13 CCC70130.1 - 0.038 13.0 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Septin TraG_N PF07916.6 CCC70130.1 - 0.044 12.2 0.1 0.054 11.9 0.1 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region AAA_14 PF13173.1 CCC70130.1 - 0.056 13.3 0.1 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF1128 PF06569.6 CCC70130.1 - 0.07 12.8 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) Formyl_trans_N PF00551.14 CCC70130.1 - 0.076 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Formyl transferase SpoIIID PF12116.3 CCC70130.1 - 0.092 12.6 0.0 3.1 7.7 0.0 2.2 2 0 0 2 2 2 0 Stage III sporulation protein D zf-H2C2_2 PF13465.1 CCC70131.1 - 1.4e-08 34.6 18.2 4.2e-06 26.7 3.5 3.6 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CCC70131.1 - 1.3e-06 28.3 16.4 0.00013 22.0 1.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC70131.1 - 0.0001 22.3 13.2 0.00074 19.6 0.9 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCC70131.1 - 0.00055 19.9 4.0 0.083 13.0 0.5 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding EKR PF10371.4 CCC70131.1 - 0.0057 16.2 0.1 0.016 14.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function AMPKBI PF04739.10 CCC70132.1 - 8e-32 109.1 4.0 8e-32 109.1 2.7 2.1 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain ACOX PF01756.14 CCC70133.1 - 1e-46 158.6 0.0 1.9e-46 157.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 CCC70133.1 - 2.1e-16 59.1 0.2 4.1e-16 58.2 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 CCC70133.1 - 2e-10 41.0 0.1 5e-10 39.7 0.1 1.6 1 1 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 CCC70133.1 - 0.0019 18.3 0.0 0.0061 16.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain CDP-OH_P_transf PF01066.16 CCC70134.1 - 1.8e-11 44.2 2.9 3.7e-11 43.2 2.0 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF2905 PF11146.3 CCC70134.1 - 0.046 13.6 0.4 0.13 12.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2905) Nefa_Nip30_N PF10187.4 CCC70135.1 - 2e-07 31.1 13.8 2e-07 31.1 9.5 1.7 1 1 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Peptidase_S46 PF10459.4 CCC70135.1 - 0.079 11.3 4.6 0.094 11.1 3.2 1.1 1 0 0 1 1 1 0 Peptidase S46 Nop25 PF09805.4 CCC70135.1 - 0.35 10.9 13.6 0.68 9.9 9.2 1.7 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF3347 PF11827.3 CCC70135.1 - 6.6 6.6 10.0 0.56 10.1 3.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3347) Peptidase_S10 PF00450.17 CCC70136.1 - 5.1e-101 338.8 1.6 7.2e-101 338.3 1.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase CDC45 PF02724.9 CCC70136.1 - 3.5e-05 22.0 17.4 4.9e-05 21.5 12.0 1.3 1 0 0 1 1 1 1 CDC45-like protein BUD22 PF09073.5 CCC70136.1 - 6.9e-05 22.1 27.9 0.00011 21.4 19.3 1.2 1 0 0 1 1 1 1 BUD22 CENP-T PF15511.1 CCC70136.1 - 0.32 10.2 23.2 0.019 14.2 12.3 1.6 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T SAPS PF04499.10 CCC70136.1 - 0.45 9.0 10.5 0.67 8.5 7.3 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2722 PF10846.3 CCC70136.1 - 0.62 9.0 11.5 1.1 8.1 7.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) PPP4R2 PF09184.6 CCC70136.1 - 0.69 9.4 30.7 3 7.3 21.3 2.2 1 0 0 1 1 1 0 PPP4R2 FLO_LFY PF01698.11 CCC70136.1 - 1.4 7.6 10.6 2.3 6.9 7.4 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein NPR3 PF03666.8 CCC70136.1 - 6 5.2 7.3 10 4.5 5.1 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Ycf1 PF05758.7 CCC70136.1 - 6.9 4.2 8.5 11 3.6 5.9 1.2 1 0 0 1 1 1 0 Ycf1 Astro_capsid PF03115.9 CCC70136.1 - 8 4.5 14.3 13 3.9 9.9 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Aminotran_1_2 PF00155.16 CCC70137.1 - 4.4e-21 75.2 0.0 5.7e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 CCC70137.1 - 0.018 14.0 0.2 0.095 11.7 0.1 2.0 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 CCC70137.1 - 0.21 10.6 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase MCM PF00493.18 CCC70138.1 - 4.9e-139 462.7 0.7 7.1e-139 462.2 0.5 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCC70138.1 - 3.9e-21 75.7 3.8 5.9e-21 75.1 0.1 2.9 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCC70138.1 - 3.3e-07 29.6 0.0 1.3e-06 27.7 0.0 2.0 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCC70138.1 - 0.0061 16.0 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 CCC70138.1 - 0.01 15.5 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 CCC70138.1 - 0.019 14.5 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RVT_2 PF07727.9 CCC70139.1 - 1.8e-20 73.0 0.0 2.4e-20 72.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EFhand_Ca_insen PF08726.5 CCC70139.1 - 0.028 14.3 0.0 0.058 13.3 0.0 1.5 1 0 0 1 1 1 0 Ca2+ insensitive EF hand SKN1 PF03935.10 CCC70140.1 - 1.1e-255 848.4 3.3 1.5e-255 848.0 2.3 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Asp-B-Hydro_N PF05279.6 CCC70141.1 - 0.99 9.1 28.5 1.8 8.3 19.7 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF946 PF06101.6 CCC70142.1 - 1e-05 23.7 1.2 1e-05 23.7 0.9 1.7 2 0 0 2 2 2 1 Plant protein of unknown function (DUF946) GCR1_C PF12550.3 CCC70143.1 - 4.6e-14 52.0 0.3 4.6e-14 52.0 0.2 2.0 2 0 0 2 2 2 1 Transcriptional activator of glycolytic enzymes DUF2406 PF10295.4 CCC70144.1 - 1e-19 70.7 0.2 2.6e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) MFS_1 PF07690.11 CCC70145.1 - 6.5e-32 110.6 29.6 6.5e-32 110.6 20.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 CCC70145.1 - 2.1e-13 49.6 22.9 5.2e-13 48.3 15.2 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter Proteasome PF00227.21 CCC70146.1 - 3.3e-58 196.1 0.7 4.3e-58 195.7 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCC70146.1 - 2.3e-13 49.1 0.2 4.2e-13 48.3 0.2 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Lipocalin_6 PF13944.1 CCC70146.1 - 0.023 14.8 4.1 2.4 8.2 1.4 2.1 2 0 0 2 2 2 0 Lipocalin-like domain Replic_Relax PF13814.1 CCC70146.1 - 0.051 13.4 0.0 0.087 12.6 0.0 1.3 1 0 0 1 1 1 0 Replication-relaxation UQ_con PF00179.21 CCC70148.1 - 1.7e-36 124.6 2.8 2.8e-36 124.0 1.9 1.3 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCC70148.1 - 0.00024 20.9 4.8 0.00073 19.4 3.5 1.7 1 1 0 1 1 1 1 RWD domain UFC1 PF08694.6 CCC70148.1 - 0.00025 20.5 0.1 0.00042 19.8 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 Prok-E2_B PF14461.1 CCC70148.1 - 0.059 13.1 0.9 0.11 12.2 0.4 1.5 1 1 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.8 CCC70148.1 - 0.059 13.0 1.0 0.091 12.4 0.7 1.4 1 0 0 1 1 1 0 UEV domain Band_7 PF01145.20 CCC70149.1 - 8.7e-28 97.4 1.3 1.5e-27 96.6 0.9 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 CCC70149.1 - 0.031 13.6 0.7 0.049 13.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Band_7_1 PF13421.1 CCC70149.1 - 0.084 12.3 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family MARVEL PF01284.18 CCC70150.1 - 1.2e-23 83.5 12.1 1.6e-23 83.1 8.4 1.1 1 0 0 1 1 1 1 Membrane-associating domain ketoacyl-synt PF00109.21 CCC70151.1 - 0.059 12.8 1.4 0.64 9.4 0.0 2.5 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain SYF2 PF08231.7 CCC70152.1 - 3.2e-10 40.3 21.3 3.2e-10 40.3 14.7 1.7 1 1 1 2 2 2 1 SYF2 splicing factor IF3_N PF05198.11 CCC70152.1 - 0.031 14.1 1.8 0.072 13.0 1.2 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-3, N-terminal domain UpxZ PF06603.6 CCC70152.1 - 0.075 13.0 0.2 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 UpxZ family of transcription anti-terminator antagonists NusA_N PF08529.6 CCC70152.1 - 0.24 11.3 10.7 0.18 11.8 0.6 2.3 2 0 0 2 2 2 0 NusA N-terminal domain UPF0515 PF15135.1 CCC70152.1 - 4.7 6.1 11.0 1.8 7.5 3.7 1.9 1 1 1 2 2 2 0 Uncharacterised protein UPF0515 Utp8 PF10395.4 CCC70153.1 - 6.2e-214 712.1 34.8 7e-214 711.9 24.1 1.0 1 0 0 1 1 1 1 Utp8 family NRDE PF05742.7 CCC70154.1 - 2e-57 194.5 0.0 2.3e-57 194.3 0.0 1.0 1 0 0 1 1 1 1 NRDE protein Abhydrolase_6 PF12697.2 CCC70156.1 - 7.3e-21 75.1 0.0 1e-20 74.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC70156.1 - 4.5e-18 65.6 0.3 6.8e-18 65.0 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 CCC70156.1 - 3.8e-07 29.9 0.0 1.5e-06 28.0 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 CCC70156.1 - 1.7e-05 24.5 0.0 3.8e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Acetyltransf_7 PF13508.1 CCC70157.1 - 3.5e-06 27.0 0.0 8.5e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCC70157.1 - 0.0003 20.7 0.1 0.0019 18.2 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 CCC70157.1 - 0.0049 16.7 0.1 0.041 13.7 0.0 2.4 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain DUF3954 PF13128.1 CCC70157.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) FR47 PF08445.5 CCC70157.1 - 0.041 13.6 0.0 0.13 12.0 0.0 1.9 1 1 0 1 1 1 0 FR47-like protein AMPKBI PF04739.10 CCC70157.1 - 0.074 12.9 0.2 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 5'-AMP-activated protein kinase beta subunit, interation domain TLD PF07534.11 CCC70157.1 - 0.097 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 TLD SURF1 PF02104.10 CCC70158.1 - 7.8e-63 212.1 0.1 1.2e-62 211.5 0.0 1.3 1 0 0 1 1 1 1 SURF1 family DASH_Dam1 PF08653.5 CCC70159.1 - 1.4e-28 98.3 0.1 2.8e-28 97.4 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Dam1 CD36 PF01130.16 CCC70159.1 - 0.019 13.3 0.2 0.026 12.8 0.1 1.2 1 0 0 1 1 1 0 CD36 family GnHR_trans PF12369.3 CCC70159.1 - 4.3 7.8 7.2 8.7 6.8 2.0 3.0 3 0 0 3 3 3 0 Gonadotropin hormone receptor transmembrane region LSM14 PF12701.2 CCC70160.1 - 5.7e-24 83.7 0.0 1.4e-23 82.5 0.0 1.7 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 CCC70160.1 - 4.9e-14 52.7 6.7 4.9e-14 52.7 4.6 2.2 2 0 0 2 2 2 1 FDF domain API5 PF05918.6 CCC70160.1 - 0.016 13.7 4.8 0.02 13.4 3.3 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SM-ATX PF14438.1 CCC70160.1 - 0.016 15.1 0.2 0.1 12.5 0.0 2.2 2 0 0 2 2 2 0 Ataxin 2 SM domain FXR1P_C PF12235.3 CCC70160.1 - 1.3 9.1 23.0 2.4 8.2 10.5 3.1 3 1 0 3 3 3 0 Fragile X-related 1 protein C terminal LisH PF08513.6 CCC70161.1 - 3.4e-05 23.4 0.2 8.5e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 LisH WD40 PF00400.27 CCC70161.1 - 0.001 18.8 0.1 0.15 12.0 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat PQQ_2 PF13360.1 CCC70161.1 - 0.074 12.5 0.0 0.69 9.3 0.0 2.4 1 1 1 3 3 3 0 PQQ-like domain Ribosom_S12_S23 PF00164.20 CCC70162.1 - 7.9e-41 138.3 0.5 9.3e-41 138.0 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Nup54 PF13874.1 CCC70163.1 - 6.9e-42 142.4 3.3 6.9e-42 142.4 2.3 2.6 2 1 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 CCC70163.1 - 6.2e-27 94.1 142.0 1.5e-11 44.4 31.4 4.3 1 1 2 3 3 3 3 Nucleoporin FG repeat region COG2 PF06148.6 CCC70164.1 - 6.3e-05 22.8 7.7 0.00022 21.0 4.0 2.7 1 1 1 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4208 PF13907.1 CCC70164.1 - 0.0016 18.6 1.1 0.0059 16.8 0.5 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF4208) Glu-tRNAGln PF02686.10 CCC70164.1 - 0.019 14.7 0.7 0.047 13.4 0.3 1.9 1 1 0 1 1 1 0 Glu-tRNAGln amidotransferase C subunit Sulfate_transp PF00916.15 CCC70165.1 - 3e-52 177.3 11.9 6.9e-52 176.1 8.2 1.6 1 0 0 1 1 1 1 Sulfate transporter family STAS PF01740.16 CCC70165.1 - 1e-14 53.9 0.9 2.2e-14 52.8 0.6 1.6 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 CCC70165.1 - 0.0051 16.6 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain zf-CCHC PF00098.18 CCC70166.1 - 5.5e-06 26.0 1.3 1.2e-05 24.9 0.9 1.6 1 0 0 1 1 1 1 Zinc knuckle Asp_protease_2 PF13650.1 CCC70166.1 - 0.0021 18.4 0.0 0.005 17.3 0.0 1.6 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 CCC70166.1 - 0.0058 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease eIF3g PF12353.3 CCC70166.1 - 0.018 14.9 0.3 0.035 14.0 0.2 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_2 PF13696.1 CCC70166.1 - 0.066 12.7 0.7 0.066 12.7 0.5 1.7 2 0 0 2 2 2 0 Zinc knuckle Cyclin_N PF00134.18 CCC70168.1 - 5.8e-38 129.3 0.1 1.5e-37 128.0 0.0 1.7 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCC70168.1 - 2.7e-18 66.0 0.0 7.9e-18 64.5 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Cyclin_N PF00134.18 CCC70169.1 - 3.5e-40 136.4 0.2 4.9e-39 132.7 0.1 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCC70169.1 - 8.6e-31 106.3 0.0 2.3e-30 104.9 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain ATP-synt_S1 PF05827.7 CCC70170.1 - 0.00055 19.3 0.1 0.0013 18.0 0.0 1.7 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) ODV-E18 PF10717.4 CCC70170.1 - 0.04 13.3 0.0 0.075 12.4 0.0 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF912 PF06024.7 CCC70170.1 - 0.046 13.7 0.1 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) VMA21 PF09446.5 CCC70171.1 - 2.3e-18 65.8 6.1 3e-18 65.4 4.2 1.2 1 0 0 1 1 1 1 VMA21-like domain MscS_TM PF12794.2 CCC70171.1 - 0.019 13.6 0.0 0.019 13.6 0.0 1.0 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF1118 PF06549.7 CCC70171.1 - 0.037 14.1 0.1 0.044 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) DUF3357 PF11837.3 CCC70171.1 - 0.22 11.3 0.7 11 5.9 0.4 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) ATG22 PF11700.3 CCC70171.1 - 0.27 9.6 2.1 0.3 9.5 1.5 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF1385 PF07136.6 CCC70171.1 - 0.33 9.9 1.8 0.36 9.8 1.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1385) Med18 PF09637.5 CCC70172.1 - 3.3e-64 216.8 0.7 3.7e-64 216.6 0.5 1.0 1 0 0 1 1 1 1 Med18 protein Pescadillo_N PF06732.6 CCC70173.1 - 1.7e-123 411.3 0.6 1.7e-123 411.3 0.4 2.8 3 1 1 4 4 4 1 Pescadillo N-terminus BRCT PF00533.21 CCC70173.1 - 4.6e-11 42.7 0.0 4.4e-10 39.5 0.0 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Rhomboid PF01694.17 CCC70175.1 - 2.1e-29 102.4 15.9 2.1e-29 102.4 11.0 1.6 2 0 0 2 2 2 1 Rhomboid family RabGAP-TBC PF00566.13 CCC70176.1 - 3.1e-52 177.1 0.3 3.1e-52 177.1 0.2 2.1 2 0 0 2 2 2 1 Rab-GTPase-TBC domain GRAM PF02893.15 CCC70176.1 - 3.5e-13 48.8 0.0 1.1e-12 47.2 0.0 2.0 1 0 0 1 1 1 1 GRAM domain EF-hand_7 PF13499.1 CCC70176.1 - 1.4e-05 25.1 1.6 5e-05 23.3 0.8 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 CCC70176.1 - 1.5e-05 24.4 0.5 0.0019 17.9 0.0 3.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 CCC70176.1 - 0.0083 15.3 0.3 0.043 13.1 0.0 2.4 2 0 0 2 2 2 1 EF hand Telomere_reg-2 PF10193.4 CCC70177.1 - 1.1e-27 96.6 1.1 2.8e-26 92.0 0.1 3.1 2 1 0 2 2 2 1 Telomere length regulation protein Peptidase_C50 PF03568.12 CCC70178.1 - 3.9e-124 414.2 0.1 3.9e-124 414.2 0.1 1.9 2 0 0 2 2 2 1 Peptidase family C50 Flavin_Reduct PF01613.13 CCC70179.1 - 3.3e-30 104.9 0.0 4.2e-30 104.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Mito_carr PF00153.22 CCC70181.1 - 5.9e-59 195.7 2.5 5e-19 67.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tape_meas_lam_C PF09718.5 CCC70181.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.6 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) RNase_PH PF01138.16 CCC70182.1 - 5.2e-18 65.6 0.1 8.2e-18 64.9 0.1 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCC70182.1 - 5.2e-06 26.3 2.1 7.6e-06 25.7 0.3 2.1 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 tRNA-synt_1 PF00133.17 CCC70183.1 - 8.1e-216 717.6 0.4 4.3e-215 715.2 0.3 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCC70183.1 - 2.1e-31 108.7 1.3 5.3e-31 107.4 0.9 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCC70183.1 - 1.4e-18 66.7 0.7 2.6e-09 36.2 0.0 5.1 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 CCC70183.1 - 2e-10 40.2 0.2 2.5e-07 30.2 0.1 2.8 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 CCC70183.1 - 1.9e-06 27.8 2.4 1.9e-06 27.8 1.6 2.3 2 0 0 2 2 2 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1e PF01406.14 CCC70183.1 - 0.0006 19.0 0.1 0.067 12.2 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 CCC70183.1 - 0.021 13.6 2.8 0.074 11.8 0.0 3.0 4 0 0 4 4 4 0 tRNA synthetases class I (R) DASH_Duo1 PF08651.5 CCC70183.1 - 0.79 9.3 6.3 5 6.7 2.9 3.1 3 0 0 3 3 3 0 DASH complex subunit Duo1 CwfJ_C_1 PF04677.10 CCC70184.1 - 2.6e-31 107.8 0.0 5.9e-31 106.6 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 CCC70184.1 - 2.3e-20 72.9 0.7 5.5e-20 71.6 0.5 1.7 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 Pkinase PF00069.20 CCC70185.1 - 2.2e-53 181.0 0.1 2.4e-52 177.6 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC70185.1 - 7e-28 97.3 0.5 9.3e-20 70.7 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 CCC70185.1 - 6.1e-05 23.4 2.2 0.00019 21.8 0.7 2.3 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCC70185.1 - 0.00021 20.3 0.1 0.0022 17.0 0.1 2.3 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCC70185.1 - 0.0093 15.0 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC70185.1 - 0.12 12.1 0.0 0.4 10.3 0.0 1.8 1 1 0 2 2 2 0 Phosphotransferase enzyme family Nop PF01798.13 CCC70186.1 - 1.8e-44 150.6 0.2 4.1e-44 149.5 0.1 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 CCC70186.1 - 1.4e-31 109.4 6.1 1.4e-31 109.4 4.2 2.1 3 0 0 3 3 3 1 Prp31 C terminal domain NOSIC PF08060.8 CCC70186.1 - 7.7e-08 32.0 0.2 1.9e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain Nrap PF03813.9 CCC70187.1 - 0 1226.3 5.4 0 1226.1 3.7 1.0 1 0 0 1 1 1 1 Nrap protein NOA36 PF06524.7 CCC70187.1 - 9.3 5.4 8.2 16 4.6 5.7 1.3 1 0 0 1 1 1 0 NOA36 protein Lipoprotein_20 PF13942.1 CCC70188.1 - 0.0068 15.9 0.5 0.0068 15.9 0.4 3.6 2 1 1 3 3 3 2 YfhG lipoprotein DUF1664 PF07889.7 CCC70188.1 - 0.18 11.6 27.5 0.24 11.1 2.7 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Catalase PF00199.14 CCC70189.1 - 1.8e-151 504.2 2.2 3.9e-150 499.7 1.5 2.1 1 1 0 1 1 1 1 Catalase Catalase-rel PF06628.7 CCC70189.1 - 2.4e-13 49.7 0.5 1.1e-12 47.5 0.0 2.4 3 0 0 3 3 3 1 Catalase-related immune-responsive Pil1 PF13805.1 CCC70190.1 - 3.5e-150 498.6 0.6 4.1e-150 498.3 0.4 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 DUF3660 PF12398.3 CCC70191.1 - 0.23 11.3 1.4 8.8 6.2 0.0 2.7 2 0 0 2 2 2 0 Receptor serine/threonine kinase IF-2B PF01008.12 CCC70192.1 - 2.4e-105 351.5 0.1 2.4e-105 351.5 0.1 2.1 2 0 0 2 2 2 1 Initiation factor 2 subunit family DeoRC PF00455.17 CCC70192.1 - 8.2e-05 22.2 0.9 0.0036 16.9 0.6 2.6 1 1 0 1 1 1 1 DeoR C terminal sensor domain STb_secrete PF09075.5 CCC70192.1 - 0.11 12.3 0.2 0.81 9.5 0.1 2.2 2 0 0 2 2 2 0 Heat-stable enterotoxin B, secretory Sulfotransfer_2 PF03567.9 CCC70192.1 - 1.4 8.5 7.2 0.13 11.9 0.9 2.1 2 0 0 2 2 2 0 Sulfotransferase family GAGA_bind PF06217.7 CCC70192.1 - 5.2 6.9 23.3 16 5.3 0.1 2.2 2 0 0 2 2 2 0 GAGA binding protein-like family SR-25 PF10500.4 CCC70192.1 - 5.2 6.4 39.1 2.1 7.7 18.7 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF1168 PF06658.7 CCC70192.1 - 7.6 6.0 39.1 1.5 8.3 16.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) MAS20 PF02064.10 CCC70193.1 - 3.7e-21 75.2 0.5 3.1e-20 72.2 0.4 2.0 1 1 0 1 1 1 1 MAS20 protein import receptor DUF2984 PF11203.3 CCC70193.1 - 0.035 14.2 0.1 0.051 13.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2984) DUF733 PF05306.6 CCC70193.1 - 0.037 14.2 1.1 0.1 12.8 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF733) DivIC PF04977.10 CCC70193.1 - 3.5 7.1 6.7 5 6.6 3.8 1.8 2 0 0 2 2 2 0 Septum formation initiator SLX9 PF15341.1 CCC70194.1 - 7.6e-23 81.2 12.2 1.3e-22 80.5 8.5 1.4 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 PEX11 PF05648.9 CCC70195.1 - 3.4e-58 196.5 4.0 3.8e-58 196.3 2.8 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) T4_baseplate PF12322.3 CCC70195.1 - 0.13 11.5 0.1 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 T4 bacteriophage base plate protein Sld5 PF05916.6 CCC70196.1 - 4.2e-14 52.7 0.0 5.4e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein AAA PF00004.24 CCC70197.1 - 1.1e-54 184.2 0.0 4.5e-45 153.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCC70197.1 - 2e-05 24.7 0.0 0.011 15.8 0.0 3.6 3 1 1 4 4 3 1 AAA domain AAA_17 PF13207.1 CCC70197.1 - 4e-05 24.4 0.2 0.0019 18.9 0.0 3.2 3 1 0 3 3 3 1 AAA domain AAA_2 PF07724.9 CCC70197.1 - 6.9e-05 22.8 0.0 0.00021 21.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 CCC70197.1 - 0.00019 20.9 0.1 0.024 14.0 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 CCC70197.1 - 0.00028 20.0 0.0 0.00071 18.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 CCC70197.1 - 0.00039 19.3 0.1 0.0011 17.9 0.0 1.7 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.17 CCC70197.1 - 0.0014 18.7 0.0 0.0053 16.9 0.0 2.1 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.12 CCC70197.1 - 0.0016 17.9 0.2 0.0065 15.9 0.0 2.1 3 0 0 3 3 2 1 IstB-like ATP binding protein AAA_5 PF07728.9 CCC70197.1 - 0.0023 17.6 0.0 0.011 15.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCC70197.1 - 0.0039 17.1 0.0 0.085 12.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CCC70197.1 - 0.0047 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CCC70197.1 - 0.0097 14.6 0.1 0.024 13.3 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus HIN PF02760.10 CCC70197.1 - 0.011 15.1 0.2 0.023 14.0 0.1 1.5 1 0 0 1 1 1 0 HIN-200/IF120x domain KaiC PF06745.8 CCC70197.1 - 0.012 14.6 0.0 0.031 13.3 0.0 1.6 1 0 0 1 1 1 0 KaiC Mg_chelatase PF01078.16 CCC70197.1 - 0.014 14.5 0.1 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Glu_cys_ligase PF04262.9 CCC70197.1 - 0.017 13.6 0.1 0.029 12.8 0.0 1.3 1 0 0 1 1 1 0 Glutamate-cysteine ligase AAA_19 PF13245.1 CCC70197.1 - 0.022 14.4 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 CCC70197.1 - 0.036 14.3 0.0 0.096 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 CCC70197.1 - 0.053 13.1 0.2 0.17 11.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 CCC70197.1 - 0.1 11.8 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_28 PF13521.1 CCC70197.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCC70197.1 - 0.18 11.6 0.0 0.67 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain DnaJ PF00226.26 CCC70198.1 - 4.4e-06 26.3 0.1 7e-06 25.6 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 CCC70198.1 - 0.0082 15.9 0.1 0.0095 15.7 0.1 1.2 1 0 0 1 1 1 1 Pam16 DUF2382 PF09557.5 CCC70199.1 - 0.11 12.4 0.4 9.5 6.1 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF2382) zf-DHHC PF01529.15 CCC70200.1 - 9.4e-40 135.8 9.3 9.4e-40 135.8 6.5 1.6 1 1 1 2 2 2 1 DHHC palmitoyltransferase TMEMspv1-c74-12 PF11044.3 CCC70200.1 - 0.11 12.1 0.3 0.11 12.1 0.2 2.5 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Pox_A14 PF05767.7 CCC70200.1 - 0.12 12.3 3.8 0.75 9.7 0.5 2.3 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Syja_N PF02383.13 CCC70201.1 - 3.3e-92 308.6 3.5 6.7e-92 307.6 0.0 2.5 3 0 0 3 3 3 2 SacI homology domain Na_Ca_ex PF01699.19 CCC70203.1 - 1.6e-26 92.5 26.3 1.3e-16 60.4 5.9 4.6 5 1 1 6 6 6 2 Sodium/calcium exchanger protein DUF307 PF03733.8 CCC70203.1 - 2.8e-15 56.4 7.7 2.8e-15 56.4 5.3 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF307) Abhydrolase_5 PF12695.2 CCC70204.1 - 6.5e-16 58.4 0.0 9.1e-16 57.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCC70204.1 - 1.2e-10 41.7 0.0 1.2e-08 35.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC70204.1 - 9e-09 35.2 0.0 2.2e-06 27.4 0.0 2.4 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 CCC70204.1 - 1.7e-08 33.9 0.0 1.1e-07 31.2 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family BAAT_C PF08840.6 CCC70204.1 - 4.7e-05 23.1 0.0 0.00069 19.3 0.0 2.1 1 1 1 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 CCC70204.1 - 0.00065 19.1 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DUF818 PF05677.7 CCC70204.1 - 0.013 14.2 0.4 0.02 13.6 0.3 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Peptidase_S15 PF02129.13 CCC70204.1 - 0.018 14.4 0.0 0.42 9.9 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1057 PF06342.7 CCC70204.1 - 0.019 13.8 0.0 0.029 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.3 CCC70204.1 - 0.029 14.1 0.0 0.053 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Esterase PF00756.15 CCC70204.1 - 0.088 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Putative esterase DUF1749 PF08538.5 CCC70204.1 - 0.13 11.0 0.0 0.35 9.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Sugar_tr PF00083.19 CCC70205.1 - 6.5e-116 387.5 36.1 7.5e-116 387.3 25.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC70205.1 - 3.1e-19 68.9 35.8 7.6e-17 61.0 17.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PDT PF00800.13 CCC70206.1 - 3.9e-55 186.2 0.3 5.1e-55 185.8 0.2 1.1 1 0 0 1 1 1 1 Prephenate dehydratase DUF436 PF04260.7 CCC70206.1 - 0.022 14.2 0.0 0.039 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF436) ACT PF01842.20 CCC70206.1 - 0.022 14.2 0.0 0.047 13.1 0.0 1.6 1 0 0 1 1 1 0 ACT domain DNA_pol_E_B PF04042.11 CCC70206.1 - 0.061 12.5 0.0 0.086 12.0 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B ATP11 PF06644.6 CCC70207.1 - 1.6e-90 303.2 2.4 1.9e-90 302.9 1.7 1.0 1 0 0 1 1 1 1 ATP11 protein Exonuc_X-T_C PF08411.5 CCC70207.1 - 0.0085 15.1 3.6 0.013 14.4 2.5 1.3 1 0 0 1 1 1 1 Exonuclease C-terminal DUF2115 PF09888.4 CCC70207.1 - 0.036 14.1 2.0 0.071 13.2 1.4 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) Sigma70_r1_1 PF03979.9 CCC70207.1 - 0.087 12.7 1.8 0.17 11.8 1.3 1.5 1 0 0 1 1 1 0 Sigma-70 factor, region 1.1 DUF3571 PF12095.3 CCC70207.1 - 0.12 12.5 1.5 0.3 11.3 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3571) Prenyltransf PF01255.14 CCC70208.1 - 6.6e-79 264.1 0.0 8.5e-79 263.7 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Pyrophosphatase PF00719.14 CCC70209.1 - 4.1e-53 179.0 0.3 5.6e-53 178.5 0.2 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase PRAI PF00697.17 CCC70210.1 - 2.8e-56 190.2 0.0 3.2e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase FMN_dh PF01070.13 CCC70210.1 - 0.0022 16.9 0.1 1.8 7.3 0.0 2.5 3 0 0 3 3 3 2 FMN-dependent dehydrogenase DeoC PF01791.4 CCC70210.1 - 0.015 14.5 0.3 9.8 5.3 0.0 3.3 3 0 0 3 3 3 0 DeoC/LacD family aldolase Histone PF00125.19 CCC70211.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCC70211.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCC70211.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCC70211.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CCC70212.1 - 2.5e-15 56.3 0.2 3.1e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCC70212.1 - 3.2e-05 23.8 0.1 5.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CCC70212.1 - 4.4e-05 23.3 0.2 6.2e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CCC70212.1 - 5e-05 23.3 0.1 7e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CCC70212.1 - 0.0012 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CCC70212.1 - 0.0042 16.7 0.0 0.0052 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 CCC70212.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 CCC70212.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Tcp11 PF05794.8 CCC70213.1 - 3.3e-84 283.1 7.7 6.3e-84 282.2 5.3 1.4 1 0 0 1 1 1 1 T-complex protein 11 Ribonuclease_3 PF00636.21 CCC70213.1 - 0.39 11.1 2.7 3.6 8.0 0.5 2.8 2 0 0 2 2 2 0 Ribonuclease III domain Sel1 PF08238.7 CCC70214.1 - 3.1e-10 40.3 3.5 4.2e-06 27.2 0.1 3.3 3 0 0 3 3 3 2 Sel1 repeat Aldedh PF00171.17 CCC70215.1 - 1.1e-157 525.0 0.1 1.3e-157 524.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 CCC70215.1 - 0.00095 18.4 0.0 0.0021 17.3 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) OmdA PF13376.1 CCC70215.1 - 0.049 13.3 0.3 0.049 13.3 0.2 2.0 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated RCR PF12273.3 CCC70216.1 - 0.059 13.9 0.1 0.059 13.9 0.1 2.2 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red DUF2365 PF10157.4 CCC70216.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) Mannosyl_trans2 PF04188.8 CCC70217.1 - 3.4e-77 260.2 33.0 9.9e-60 202.6 16.0 2.0 1 1 1 2 2 2 2 Mannosyltransferase (PIG-V)) Ran_BP1 PF00638.13 CCC70218.1 - 1.4e-53 180.1 1.8 2.2e-53 179.4 1.2 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 CCC70218.1 - 2.5e-06 27.2 1.3 1.4e-05 24.7 0.9 2.0 1 1 0 1 1 1 1 WH1 domain VID27 PF08553.5 CCC70218.1 - 3.1e-05 22.4 2.2 3.4e-05 22.3 1.5 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein SR-25 PF10500.4 CCC70218.1 - 0.16 11.4 6.7 0.23 10.8 4.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Trehalase PF01204.13 CCC70219.1 - 1.6e-186 620.9 0.0 2.4e-186 620.3 0.0 1.3 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 CCC70219.1 - 1.3e-15 56.3 2.2 2.3e-15 55.6 1.5 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Dicty_REP PF05086.7 CCC70219.1 - 1.7 6.3 7.4 2.5 5.7 5.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF1640 PF07798.6 CCC70220.1 - 4.5e-59 199.4 6.7 5.6e-59 199.1 4.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) TBPIP PF07106.8 CCC70220.1 - 0.0077 15.8 8.4 0.015 14.8 5.8 1.4 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF1732 PF08340.6 CCC70220.1 - 0.029 14.2 5.4 0.047 13.5 3.5 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1732) CENP-K PF11802.3 CCC70220.1 - 0.035 13.3 3.6 0.038 13.2 2.5 1.2 1 0 0 1 1 1 0 Centromere-associated protein K FTA4 PF13093.1 CCC70220.1 - 0.082 12.3 7.2 0.092 12.1 4.6 1.3 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Spore_GerAC PF05504.6 CCC70220.1 - 0.087 12.6 4.2 0.18 11.5 2.8 1.9 1 1 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal FlaC_arch PF05377.6 CCC70220.1 - 0.11 12.3 2.0 6.5 6.7 0.1 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF342 PF03961.8 CCC70220.1 - 0.13 10.6 7.4 0.16 10.3 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 CCC70220.1 - 0.33 10.7 4.4 4.7 7.0 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.7 CCC70220.1 - 0.37 10.6 2.6 12 5.7 1.8 2.3 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus YlqD PF11068.3 CCC70220.1 - 3.1 7.8 10.3 1.1 9.2 2.4 2.2 1 1 1 2 2 2 0 YlqD protein HALZ PF02183.13 CCC70220.1 - 3.7 7.3 7.2 1.7 8.4 0.6 3.2 4 1 0 4 4 4 0 Homeobox associated leucine zipper Phage_lysis PF03245.8 CCC70220.1 - 4.1 7.3 8.3 1.2 9.1 0.4 2.3 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein PMM PF03332.8 CCC70221.1 - 1.3e-113 377.9 0.4 1.5e-113 377.7 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 CCC70221.1 - 9.1e-05 22.1 0.0 0.0014 18.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TMPIT PF07851.8 CCC70221.1 - 0.0041 16.2 0.0 0.0054 15.8 0.0 1.1 1 0 0 1 1 1 1 TMPIT-like protein USP8_dimer PF08969.6 CCC70222.1 - 8.7e-09 35.3 2.6 1.2e-08 34.9 0.7 2.0 1 1 1 2 2 2 1 USP8 dimerisation domain Tbf5 PF06331.7 CCC70222.1 - 0.13 12.0 0.1 0.26 11.0 0.1 1.6 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 DUF3091 PF11291.3 CCC70222.1 - 0.83 9.6 7.5 0.41 10.6 3.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3091) GRAM PF02893.15 CCC70223.1 - 1e-14 53.7 0.1 2.6e-14 52.4 0.1 1.8 1 0 0 1 1 1 1 GRAM domain SPC22 PF04573.7 CCC70224.1 - 1.6e-52 177.2 2.4 2e-52 176.9 1.7 1.1 1 0 0 1 1 1 1 Signal peptidase subunit DUF2206 PF09971.4 CCC70224.1 - 0.016 14.0 1.9 0.023 13.5 1.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2206) Sugar_tr PF00083.19 CCC70225.1 - 2.7e-69 233.8 27.3 1.5e-68 231.4 18.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC70225.1 - 2.7e-22 78.9 31.5 3.4e-19 68.7 9.5 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 CCC70226.1 - 3.1e-57 193.7 0.1 4.7e-57 193.1 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC70226.1 - 3.8e-31 108.0 0.0 5.7e-30 104.2 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Phage_GPO PF05929.6 CCC70226.1 - 0.028 13.6 0.1 0.045 12.9 0.1 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Ldh_1_C PF02866.13 CCC70226.1 - 0.14 11.8 0.4 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain ACCA PF03255.9 CCC70226.1 - 0.16 11.5 1.3 0.39 10.2 0.9 1.6 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SH3_1 PF00018.23 CCC70227.1 - 7.6e-10 38.0 1.4 1.8e-09 36.8 0.0 2.4 2 1 1 3 3 3 1 SH3 domain SH3_9 PF14604.1 CCC70227.1 - 0.00074 19.0 0.0 0.0026 17.3 0.0 2.0 1 0 0 1 1 1 1 Variant SH3 domain HEAT_EZ PF13513.1 CCC70228.1 - 1.9e-19 69.5 0.0 4.8e-10 39.6 0.0 7.7 8 0 0 8 8 8 1 HEAT-like repeat HEAT PF02985.17 CCC70228.1 - 4.7e-18 63.5 5.3 0.014 15.4 0.0 7.8 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 CCC70228.1 - 4.3e-15 55.7 0.0 4.4e-06 26.8 0.0 6.0 4 3 1 5 5 5 3 HEAT repeats Cnd1 PF12717.2 CCC70228.1 - 2.2e-06 27.6 3.6 0.038 13.8 0.0 3.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 CCC70228.1 - 0.00053 20.3 0.0 0.39 11.1 0.0 4.4 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 CCC70228.1 - 0.0099 15.7 0.3 0.058 13.3 0.0 2.6 2 1 0 2 2 2 1 Importin-beta N-terminal domain Urb2 PF10441.4 CCC70228.1 - 0.039 13.5 0.1 0.74 9.3 0.1 2.9 2 1 1 3 3 3 0 Urb2/Npa2 family UME PF08064.8 CCC70228.1 - 0.33 10.9 8.1 4.3 7.3 0.1 4.2 5 0 0 5 5 5 0 UME (NUC010) domain Mannosyl_trans3 PF11051.3 CCC70229.1 - 1.3e-85 286.9 0.1 3.5e-85 285.6 0.0 1.7 2 0 0 2 2 2 1 Mannosyltransferase putative Glutaredoxin PF00462.19 CCC70230.1 - 2.4e-11 43.4 0.0 5e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_7 PF13899.1 CCC70230.1 - 0.0035 17.3 0.0 0.0082 16.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 CCC70230.1 - 0.13 12.4 0.1 1 9.5 0.0 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain EmrE PF13536.1 CCC70231.1 - 0.011 15.9 1.5 0.011 15.9 1.0 2.9 3 0 0 3 3 3 0 Multidrug resistance efflux transporter MerC PF03203.9 CCC70231.1 - 0.31 11.4 11.6 0.13 12.6 1.8 2.8 2 1 0 2 2 2 0 MerC mercury resistance protein SCO1-SenC PF02630.9 CCC70232.1 - 2.2e-69 232.4 0.1 3e-69 232.0 0.1 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 CCC70232.1 - 7.7e-06 25.6 0.2 0.00015 21.4 0.0 2.5 1 1 1 2 2 2 1 AhpC/TSA family Thioredoxin_8 PF13905.1 CCC70232.1 - 0.031 14.4 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.5 CCC70232.1 - 0.082 12.4 0.0 0.44 10.0 0.0 2.1 2 1 0 2 2 2 0 Redoxin ABC2_membrane PF01061.19 CCC70233.1 - 6e-66 221.5 64.5 1.9e-41 141.5 10.3 2.8 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 CCC70233.1 - 1.1e-38 132.6 0.0 4.9e-18 65.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 CCC70233.1 - 6.1e-37 125.4 5.1 3e-34 116.7 0.0 4.1 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 CCC70233.1 - 1.1e-12 47.8 0.0 9.7e-12 44.8 0.0 2.4 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 CCC70233.1 - 8.1e-09 34.9 5.2 8.1e-09 34.9 3.6 4.0 2 2 2 4 4 1 1 ABC-2 family transporter protein DUF258 PF03193.11 CCC70233.1 - 1.1e-05 24.6 0.0 0.00063 18.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCC70233.1 - 2.6e-05 23.7 0.0 0.0028 17.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCC70233.1 - 0.0001 22.3 0.2 0.0013 18.7 0.1 2.3 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 CCC70233.1 - 0.00014 21.3 0.1 0.00029 20.3 0.0 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 CCC70233.1 - 0.00058 19.9 0.0 0.89 9.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CCC70233.1 - 0.00093 19.5 0.4 0.01 16.1 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_29 PF13555.1 CCC70233.1 - 0.0013 18.2 0.0 0.072 12.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 CCC70233.1 - 0.0015 18.7 0.3 0.014 15.5 0.0 2.7 3 0 0 3 3 2 1 AAA domain Abi_2 PF07751.6 CCC70233.1 - 0.0015 18.7 1.1 0.0094 16.1 0.2 2.3 2 0 0 2 2 2 1 Abi-like protein UPF0079 PF02367.12 CCC70233.1 - 0.0062 16.1 0.5 0.31 10.6 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 CCC70233.1 - 0.0068 16.9 0.0 2.6 8.5 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein SMC_N PF02463.14 CCC70233.1 - 0.009 15.2 0.0 0.59 9.3 0.0 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 CCC70233.1 - 0.0097 16.7 0.0 0.072 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 CCC70233.1 - 0.011 15.2 0.0 1 8.7 0.0 2.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CCC70233.1 - 0.015 15.2 0.1 0.42 10.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase RNA_helicase PF00910.17 CCC70233.1 - 0.015 15.4 0.0 2.3 8.4 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_33 PF13671.1 CCC70233.1 - 0.016 15.0 0.5 0.045 13.6 0.0 2.0 3 0 0 3 3 1 0 AAA domain NACHT PF05729.7 CCC70233.1 - 0.056 13.1 0.3 0.47 10.1 0.1 2.2 2 0 0 2 2 2 0 NACHT domain ABC2_membrane PF01061.19 CCC70234.1 - 6.3e-69 231.3 58.8 2.3e-43 147.8 10.9 2.9 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 CCC70234.1 - 9.8e-40 134.3 10.3 3.1e-35 119.9 0.0 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 CCC70234.1 - 4.8e-38 130.5 0.0 5.7e-18 65.5 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 CCC70234.1 - 2.2e-11 43.7 0.0 5e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 CCC70234.1 - 1.1e-09 37.8 12.3 1.1e-09 37.8 8.6 3.2 2 2 1 3 3 3 1 ABC-2 family transporter protein DUF258 PF03193.11 CCC70234.1 - 4.2e-06 26.0 0.1 0.0008 18.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCC70234.1 - 0.00012 22.0 0.2 0.00091 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 CCC70234.1 - 0.00016 21.1 0.0 0.0045 16.4 0.0 2.5 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 CCC70234.1 - 0.00025 20.5 0.1 0.00058 19.3 0.1 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 CCC70234.1 - 0.00025 21.0 0.0 0.61 10.0 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.1 CCC70234.1 - 0.00042 19.7 0.1 0.024 14.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Miro PF08477.8 CCC70234.1 - 0.00094 19.6 0.0 0.43 11.0 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CCC70234.1 - 0.0014 18.7 0.3 0.014 15.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 CCC70234.1 - 0.0052 16.0 0.0 0.99 8.5 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 CCC70234.1 - 0.0075 16.5 0.0 0.042 14.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CCC70234.1 - 0.016 14.8 1.3 0.28 10.8 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 CCC70234.1 - 0.018 14.5 0.0 0.55 9.6 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CCC70234.1 - 0.022 14.7 0.2 0.29 11.1 0.1 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_17 PF13207.1 CCC70234.1 - 0.054 14.3 0.0 0.22 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 CCC70234.1 - 0.061 13.2 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 CCC70234.1 - 0.083 11.8 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.18 CCC70234.1 - 0.09 12.5 0.2 0.31 10.8 0.0 2.0 2 0 0 2 2 1 0 Dynamin family AAA_10 PF12846.2 CCC70234.1 - 0.17 11.2 1.4 0.92 8.8 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain NACHT PF05729.7 CCC70234.1 - 0.19 11.3 0.3 0.47 10.1 0.1 1.8 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 CCC70234.1 - 0.3 10.9 0.5 0.86 9.4 0.0 2.1 2 1 0 2 2 2 0 AAA domain ABC2_membrane PF01061.19 CCC70235.1 - 9.3e-63 211.1 61.4 5e-38 130.3 9.8 3.1 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 CCC70235.1 - 1.1e-38 130.9 9.3 3.8e-33 113.2 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 CCC70235.1 - 5.8e-36 123.8 0.0 2.5e-17 63.4 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 CCC70235.1 - 6.7e-12 45.3 0.1 6.7e-12 45.3 0.1 2.0 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 CCC70235.1 - 8.4e-09 34.9 2.5 8.4e-09 34.9 1.7 2.9 2 1 0 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 CCC70235.1 - 1.5e-05 24.2 0.0 0.0011 18.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCC70235.1 - 4.6e-05 22.9 0.0 0.0028 17.0 0.0 2.6 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 CCC70235.1 - 9.6e-05 22.4 0.5 0.0018 18.2 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain cobW PF02492.14 CCC70235.1 - 0.00033 20.1 0.1 0.00066 19.1 0.1 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 CCC70235.1 - 0.0018 18.2 0.0 0.49 10.3 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 CCC70235.1 - 0.0023 18.2 0.0 0.023 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 CCC70235.1 - 0.0024 18.3 0.0 0.16 12.4 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CCC70235.1 - 0.0042 17.2 0.4 0.021 14.9 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCC70235.1 - 0.0053 16.2 0.1 0.062 12.8 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CCC70235.1 - 0.026 14.4 0.0 0.32 10.9 0.0 2.7 3 0 0 3 3 2 0 50S ribosome-binding GTPase UPF0079 PF02367.12 CCC70235.1 - 0.031 13.9 0.7 0.45 10.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 CCC70235.1 - 0.039 13.1 0.0 1 8.5 0.0 2.7 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain Zeta_toxin PF06414.7 CCC70235.1 - 0.039 13.0 0.1 0.82 8.7 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 CCC70235.1 - 0.055 14.2 0.0 0.21 12.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCC70235.1 - 0.061 13.5 0.0 2.6 8.2 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 CCC70235.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 CCC70235.1 - 0.1 11.6 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Septin FtsK_SpoIIIE PF01580.13 CCC70235.1 - 0.11 11.9 0.0 2.5 7.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 CCC70235.1 - 0.2 11.5 0.2 0.71 9.7 0.0 2.0 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 CCC70235.1 - 0.21 11.2 0.7 0.39 10.3 0.1 1.8 2 0 0 2 2 1 0 NACHT domain GalKase_gal_bdg PF10509.4 CCC70236.1 - 2.7e-21 74.5 0.0 6.5e-21 73.3 0.0 1.7 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 CCC70236.1 - 5.5e-14 51.9 0.9 1.2e-13 50.9 0.6 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 CCC70236.1 - 1e-12 48.0 0.0 2.7e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Aldose_epim PF01263.15 CCC70237.1 - 2.3e-80 269.9 0.3 3e-80 269.5 0.2 1.2 1 0 0 1 1 1 1 Aldose 1-epimerase Epimerase PF01370.16 CCC70237.1 - 8.4e-54 182.4 0.0 1.7e-53 181.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 CCC70237.1 - 1.6e-23 82.4 0.1 2.9e-23 81.5 0.1 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 CCC70237.1 - 2.7e-17 62.5 0.0 1.9e-15 56.5 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 CCC70237.1 - 2.9e-15 55.7 0.0 9.3e-15 54.0 0.0 1.7 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 CCC70237.1 - 1.4e-12 47.1 0.0 2.3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 CCC70237.1 - 1.9e-09 37.6 0.0 3e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 CCC70237.1 - 1.6e-08 33.8 0.0 5.4e-08 32.0 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 CCC70237.1 - 1.2e-06 28.3 0.0 2.2e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 CCC70237.1 - 2.6e-06 27.5 0.0 4.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding GalP_UDP_transf PF01087.17 CCC70238.1 - 8.3e-67 224.7 0.2 1.2e-66 224.2 0.1 1.2 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 CCC70238.1 - 8.1e-65 217.4 0.3 2.3e-64 215.9 0.0 1.8 3 0 0 3 3 3 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 CCC70238.1 - 0.024 15.1 0.2 0.19 12.2 0.0 2.5 3 0 0 3 3 3 0 HIT domain ParA PF10609.4 CCC70239.1 - 2.1e-37 126.8 0.0 4e-37 125.9 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 CCC70239.1 - 1.2e-16 60.6 0.0 1.9e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 CCC70239.1 - 2e-08 33.6 0.0 7e-08 31.8 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 CCC70239.1 - 9.5e-06 24.8 0.1 5e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.1 CCC70239.1 - 2e-05 24.5 0.0 0.00042 20.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 CCC70239.1 - 0.0033 16.2 0.1 0.0065 15.2 0.1 1.4 1 0 0 1 1 1 1 ArgK protein YhjQ PF06564.7 CCC70239.1 - 0.017 14.5 0.0 0.048 13.0 0.0 1.8 1 1 0 1 1 1 0 YhjQ protein Fer4_NifH PF00142.13 CCC70239.1 - 0.025 13.7 0.0 0.27 10.3 0.0 2.0 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.15 CCC70239.1 - 0.038 13.6 0.0 0.062 12.9 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase MobB PF03205.9 CCC70239.1 - 0.05 13.3 0.3 0.19 11.4 0.1 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NUT_N PF12881.2 CCC70239.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 NUT protein N terminus AAA_25 PF13481.1 CCC70239.1 - 0.16 11.3 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gti1_Pac2 PF09729.4 CCC70240.1 - 1.6e-48 164.7 0.0 1.6e-48 164.7 0.0 4.4 2 1 0 2 2 2 1 Gti1/Pac2 family AAA PF00004.24 CCC70241.1 - 5.9e-40 136.5 0.0 1e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCC70241.1 - 8.3e-06 25.9 0.2 0.00021 21.4 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 CCC70241.1 - 1.5e-05 25.0 0.0 2.9e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CCC70241.1 - 2.7e-05 23.3 0.0 4.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Vps4_C PF09336.5 CCC70241.1 - 5.5e-05 22.9 0.4 0.00047 19.9 0.0 2.8 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.9 CCC70241.1 - 0.0001 22.0 0.0 0.00052 19.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 CCC70241.1 - 0.00033 20.1 0.2 0.086 12.2 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCC70241.1 - 0.00035 20.6 0.1 0.0045 16.9 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 CCC70241.1 - 0.0014 18.5 0.0 0.0041 17.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 CCC70241.1 - 0.0017 17.1 0.1 0.0028 16.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 C-terminus IstB_IS21 PF01695.12 CCC70241.1 - 0.0031 16.9 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 CCC70241.1 - 0.0033 16.6 0.2 0.0081 15.3 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 CCC70241.1 - 0.0057 17.4 0.1 0.045 14.5 0.0 2.6 3 1 0 3 3 2 1 AAA domain DUF815 PF05673.8 CCC70241.1 - 0.0079 15.1 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 CCC70241.1 - 0.008 16.0 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Guanylate_kin PF00625.16 CCC70241.1 - 0.01 15.2 0.4 0.46 9.8 0.0 3.1 3 0 0 3 3 3 0 Guanylate kinase AAA_19 PF13245.1 CCC70241.1 - 0.014 15.1 0.5 0.042 13.5 0.0 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_24 PF13479.1 CCC70241.1 - 0.018 14.5 0.0 0.044 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CCC70241.1 - 0.022 14.4 0.0 0.2 11.3 0.0 2.3 1 1 1 2 2 2 0 Archaeal ATPase Chromo PF00385.19 CCC70241.1 - 0.042 13.5 0.0 0.22 11.2 0.0 2.1 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain AAA_28 PF13521.1 CCC70241.1 - 0.057 13.3 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCC70241.1 - 0.057 13.7 0.0 0.18 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain NACHT PF05729.7 CCC70241.1 - 0.072 12.7 0.0 0.27 10.8 0.0 2.0 1 1 1 2 2 2 0 NACHT domain KaiC PF06745.8 CCC70241.1 - 0.091 11.8 0.2 3.7 6.5 0.0 2.3 1 1 1 2 2 2 0 KaiC PhoH PF02562.11 CCC70241.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activat PF00158.21 CCC70241.1 - 0.15 11.5 0.0 0.38 10.2 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain bZIP_1 PF00170.16 CCC70243.1 - 1.5e-08 34.4 10.1 1.5e-08 34.4 7.0 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CCC70243.1 - 1.5e-05 24.6 9.1 1.5e-05 24.6 6.3 1.7 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 CCC70243.1 - 0.023 15.0 10.5 0.029 14.6 6.6 1.8 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF3452 PF11934.3 CCC70243.1 - 0.035 13.4 1.2 0.1 11.9 0.9 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) Erg28 PF03694.8 CCC70245.1 - 1.3e-44 150.7 1.8 1.6e-44 150.4 1.2 1.1 1 0 0 1 1 1 1 Erg28 like protein MtN3_slv PF03083.11 CCC70245.1 - 0.01 15.6 1.2 0.01 15.6 0.8 1.8 1 1 0 1 1 1 0 Sugar efflux transporter for intercellular exchange Tmemb_18A PF09771.4 CCC70245.1 - 0.4 10.6 1.8 1.1 9.3 0.3 2.1 1 1 1 2 2 2 0 Transmembrane protein 188 TcpE PF12648.2 CCC70245.1 - 0.51 10.5 5.3 0.54 10.4 2.3 2.0 1 1 1 2 2 2 0 TcpE family SNF2_N PF00176.18 CCC70246.1 - 8.6e-71 238.1 0.3 1.4e-70 237.4 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCC70246.1 - 2.8e-15 55.9 0.0 1.3e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCC70246.1 - 2.1e-06 27.3 0.0 4.8e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase EF-hand_7 PF13499.1 CCC70246.1 - 0.049 13.7 0.3 0.049 13.7 0.2 3.9 3 0 0 3 3 3 0 EF-hand domain pair SWIRM PF04433.12 CCC70247.1 - 8.7e-31 105.9 0.1 2.7e-30 104.3 0.1 1.9 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 CCC70247.1 - 8.5e-14 50.8 3.8 1.3e-13 50.2 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 CCC70247.1 - 3.6e-06 26.9 0.0 6.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCC70247.1 - 8.1e-06 25.8 0.0 6.7e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Elf1 PF05129.8 CCC70247.1 - 0.047 13.3 0.2 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like STAG PF08514.6 CCC70248.1 - 1.3e-05 24.8 3.5 1.7e-05 24.4 0.4 2.8 2 1 0 2 2 2 1 STAG domain APC_CDC26 PF10471.4 CCC70249.1 - 1.2e-10 41.9 6.7 2.7e-10 40.8 4.7 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 AA_permease PF00324.16 CCC70251.1 - 8.3e-36 123.3 9.4 9.2e-36 123.1 6.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC70251.1 - 4.2e-11 42.0 8.5 5e-11 41.7 5.9 1.0 1 0 0 1 1 1 1 Amino acid permease RNA_pol_A_bac PF01000.21 CCC70253.1 - 6.4e-32 110.0 0.1 1.6e-31 108.7 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 CCC70253.1 - 7.3e-15 53.8 0.0 1e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GRP PF07172.6 CCC70255.1 - 0.56 10.7 19.2 0.34 11.4 11.4 2.1 2 0 0 2 2 2 0 Glycine rich protein family HLH PF00010.21 CCC70256.1 - 7.1e-14 51.2 0.6 2e-13 49.7 0.4 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain UCR_hinge PF02320.11 CCC70257.1 - 2e-24 85.2 3.4 3.3e-24 84.6 2.4 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 CCC70257.1 - 0.009 15.6 8.2 0.0099 15.5 5.7 1.2 1 0 0 1 1 1 1 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.7 CCC70257.1 - 0.047 13.3 12.7 0.058 13.1 8.8 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF506 PF04720.7 CCC70257.1 - 0.052 13.1 1.8 0.061 12.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) BSP_II PF05432.6 CCC70257.1 - 0.12 11.5 12.0 0.14 11.3 8.3 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Sporozoite_P67 PF05642.6 CCC70257.1 - 0.16 9.7 4.9 0.18 9.6 3.4 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nop14 PF04147.7 CCC70257.1 - 0.19 9.6 12.0 0.19 9.6 8.3 1.0 1 0 0 1 1 1 0 Nop14-like family CobT PF06213.7 CCC70257.1 - 0.2 10.7 11.9 0.24 10.4 8.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 CCC70257.1 - 0.22 9.5 4.9 0.2 9.6 3.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Myc_N PF01056.13 CCC70257.1 - 0.41 9.7 8.0 0.44 9.6 5.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF2457 PF10446.4 CCC70257.1 - 0.43 9.2 14.0 0.48 9.0 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Utp14 PF04615.8 CCC70257.1 - 0.53 8.3 9.5 0.63 8.1 6.6 1.0 1 0 0 1 1 1 0 Utp14 protein TLP-20 PF06088.6 CCC70257.1 - 0.61 9.7 3.5 0.75 9.4 2.5 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FAM176 PF14851.1 CCC70257.1 - 0.62 9.7 5.2 0.74 9.4 3.6 1.2 1 0 0 1 1 1 0 FAM176 family RRN3 PF05327.6 CCC70257.1 - 0.93 7.5 4.1 0.89 7.5 2.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1510 PF07423.6 CCC70257.1 - 0.99 8.7 6.6 1.1 8.6 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nucleoplasmin PF03066.10 CCC70257.1 - 1.6 8.2 16.6 2.9 7.4 11.5 1.4 1 0 0 1 1 1 0 Nucleoplasmin BUD22 PF09073.5 CCC70257.1 - 1.7 7.6 9.0 1.9 7.4 6.2 1.1 1 0 0 1 1 1 0 BUD22 PBP1_TM PF14812.1 CCC70257.1 - 1.8 8.8 10.8 3.3 8.0 7.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal IncA PF04156.9 CCC70257.1 - 2 7.9 4.7 2.5 7.6 3.3 1.2 1 0 0 1 1 1 0 IncA protein NOA36 PF06524.7 CCC70257.1 - 2 7.5 11.9 2.8 7.1 8.2 1.2 1 0 0 1 1 1 0 NOA36 protein Daxx PF03344.10 CCC70257.1 - 3 6.2 16.9 3.3 6.0 11.7 1.0 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 CCC70257.1 - 3.8 6.6 14.5 4.3 6.5 10.0 1.1 1 0 0 1 1 1 0 SDA1 VID27 PF08553.5 CCC70257.1 - 6.3 4.8 8.3 7 4.7 5.7 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein TRAP_alpha PF03896.11 CCC70257.1 - 6.4 5.6 8.7 7.2 5.5 6.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RXT2_N PF08595.6 CCC70257.1 - 9.1 6.0 10.6 15 5.4 7.3 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal Ribosomal_L29e PF01779.12 CCC70259.1 - 2.1e-24 85.1 8.8 3e-24 84.5 6.1 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family RRM_1 PF00076.17 CCC70260.1 - 9.4e-16 57.2 1.0 6.6e-07 28.8 0.1 3.9 2 2 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC70260.1 - 3.3e-14 52.5 0.0 9.1e-07 28.7 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC70260.1 - 1.6e-07 31.0 0.1 4.3e-05 23.2 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L2_C PF03947.13 CCC70261.1 - 1.9e-41 140.9 1.8 3e-41 140.2 1.3 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCC70261.1 - 2.4e-13 49.8 0.1 5.2e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SMC_N PF02463.14 CCC70262.1 - 1.4e-69 233.6 15.6 1.8e-67 226.7 10.8 2.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 CCC70262.1 - 1.2e-19 70.4 0.6 3.1e-19 69.1 0.2 2.0 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 CCC70262.1 - 1.4e-10 41.6 28.9 6.6e-07 29.5 0.4 4.1 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 CCC70262.1 - 2.1e-05 23.9 0.0 6.5e-05 22.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.1 CCC70262.1 - 0.0015 18.9 52.8 0.0015 18.9 36.6 6.9 2 2 0 2 2 2 1 AAA domain GAS PF13851.1 CCC70262.1 - 0.0017 17.5 7.4 0.0017 17.5 5.1 7.7 3 2 3 7 7 7 1 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 CCC70262.1 - 0.51 9.4 38.7 0.3 10.2 4.5 5.7 3 2 4 7 7 7 0 Reovirus sigma C capsid protein FAD_binding_1 PF00667.15 CCC70263.1 - 1.8e-65 220.4 0.0 3.7e-65 219.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 CCC70263.1 - 8.2e-10 39.2 0.0 6.1e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Lum_binding PF00677.12 CCC70264.1 - 8.2e-52 173.0 6.9 3.4e-26 90.9 0.2 2.3 2 0 0 2 2 2 2 Lumazine binding domain KbaA PF14089.1 CCC70264.1 - 0.085 12.3 0.1 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation Cut8_C PF08559.5 CCC70265.1 - 3.7e-39 133.8 1.8 3.7e-39 133.8 1.3 1.9 2 0 0 2 2 2 1 Cut8 six-helix bundle Cut8_M PF14483.1 CCC70265.1 - 0.0033 17.1 2.9 0.0076 16.0 2.0 1.6 1 0 0 1 1 1 1 Cut8 dimerisation domain DUF3169 PF11368.3 CCC70266.1 - 0.0081 15.3 0.0 0.0095 15.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) Sedlin_N PF04628.8 CCC70268.1 - 1.7e-45 154.0 0.0 2.7e-45 153.4 0.0 1.3 1 1 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 CCC70268.1 - 7.6e-05 22.4 0.5 0.0026 17.4 0.0 2.7 2 1 1 3 3 3 1 Sybindin-like family Med22 PF06179.7 CCC70269.1 - 3.6e-21 75.2 7.6 4.5e-21 74.9 5.2 1.0 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex CARD PF00619.16 CCC70269.1 - 0.072 12.9 1.2 0.11 12.3 0.8 1.3 1 0 0 1 1 1 0 Caspase recruitment domain DUF2973 PF11189.3 CCC70269.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) Ribosomal_S5 PF00333.15 CCC70270.1 - 2.9e-23 81.4 0.1 4.6e-23 80.7 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 CCC70270.1 - 1.3e-17 62.7 0.0 4.4e-17 61.1 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain HMG_box PF00505.14 CCC70271.1 - 2.6e-13 50.0 9.2 1.2e-12 47.8 6.4 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCC70271.1 - 0.0007 19.9 3.6 0.0017 18.6 2.5 1.6 1 1 0 1 1 1 1 HMG-box domain CblD PF07434.6 CCC70271.1 - 0.086 11.5 0.2 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 CblD like pilus biogenesis initiator DUF3724 PF12521.3 CCC70271.1 - 0.26 11.0 2.3 1.1 9.1 1.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3724) EB1 PF03271.12 CCC70273.1 - 1.5e-18 66.5 2.3 4.1e-18 65.1 1.6 1.8 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 CCC70273.1 - 8.1e-07 29.0 1.4 1.7e-06 28.0 0.9 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF4349 PF14257.1 CCC70273.1 - 0.014 14.6 0.3 2.1 7.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) zf-C4H2 PF10146.4 CCC70273.1 - 0.52 10.3 3.6 0.54 10.2 1.9 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein AMP-binding PF00501.23 CCC70274.1 - 7e-66 222.3 0.0 9e-66 221.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_8 PF13450.1 CCC70275.1 - 1.5e-06 28.1 0.0 3.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 CCC70275.1 - 0.00031 21.0 0.8 0.04 14.3 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCC70275.1 - 0.0048 15.8 0.0 0.01 14.7 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 CCC70275.1 - 0.018 14.1 0.0 0.14 11.2 0.0 1.9 1 1 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 CCC70275.1 - 0.03 14.1 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 CCC70275.1 - 0.06 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FCH PF00611.18 CCC70275.1 - 0.15 12.2 0.6 0.36 11.0 0.4 1.6 1 0 0 1 1 1 0 Fes/CIP4, and EFC/F-BAR homology domain HA2 PF04408.18 CCC70276.1 - 9.5e-28 96.2 0.4 2.7e-27 94.7 0.0 2.1 2 0 0 2 2 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 CCC70276.1 - 1.1e-24 86.5 0.4 3e-24 85.0 0.0 2.1 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 CCC70276.1 - 1.2e-12 47.5 0.0 5.8e-12 45.2 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain S1 PF00575.18 CCC70276.1 - 5.3e-11 42.4 0.7 5.3e-11 42.4 0.5 2.2 2 0 0 2 2 2 1 S1 RNA binding domain DEAD PF00270.24 CCC70276.1 - 4.4e-06 26.2 0.2 1.3e-05 24.8 0.2 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCC70276.1 - 4.4e-06 26.8 0.0 1.5e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 CCC70276.1 - 0.00031 19.7 0.0 0.0012 17.8 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein PWI PF01480.12 CCC70276.1 - 0.0031 17.5 1.7 1.5 8.9 0.1 3.0 2 0 0 2 2 2 2 PWI domain NB-ARC PF00931.17 CCC70276.1 - 0.0049 15.7 0.0 0.016 14.0 0.0 1.9 1 0 0 1 1 1 1 NB-ARC domain Sigma54_activ_2 PF14532.1 CCC70276.1 - 0.0078 16.2 0.0 0.028 14.4 0.0 2.0 1 0 0 1 1 1 1 Sigma-54 interaction domain ABC_tran PF00005.22 CCC70276.1 - 0.0088 16.3 7.1 0.35 11.1 0.1 3.7 3 1 0 4 4 4 2 ABC transporter SRP54 PF00448.17 CCC70276.1 - 0.023 14.1 0.0 0.057 12.8 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 CCC70276.1 - 0.024 14.2 0.0 0.048 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 CCC70276.1 - 0.029 14.2 2.4 0.17 11.7 0.1 3.2 2 2 1 3 3 3 0 AAA domain ATP11 PF06644.6 CCC70276.1 - 0.062 12.7 0.0 0.062 12.7 0.0 2.4 3 0 0 3 3 3 0 ATP11 protein Proteasome PF00227.21 CCC70277.1 - 3.2e-42 143.9 0.0 3.8e-42 143.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit HIM1 PF08732.5 CCC70278.1 - 1.3e-08 33.7 0.0 8.5e-07 27.7 0.0 2.1 2 0 0 2 2 2 2 HIM1 NAD_binding_10 PF13460.1 CCC70278.1 - 6e-08 32.9 0.0 8.4e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_10 PF13460.1 CCC70279.1 - 8.8e-09 35.6 0.0 1.3e-08 35.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding HIM1 PF08732.5 CCC70279.1 - 1.1e-06 27.4 0.0 3e-05 22.6 0.0 2.4 1 1 2 3 3 3 1 HIM1 Epimerase PF01370.16 CCC70279.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 CCC70279.1 - 0.016 14.4 0.0 0.027 13.7 0.0 1.4 1 1 0 1 1 1 0 NmrA-like family SRP1_TIP1 PF00660.12 CCC70280.1 - 3.1e-29 100.8 0.1 8.7e-29 99.4 0.1 1.8 1 0 0 1 1 1 1 Seripauperin and TIP1 family PIR PF00399.14 CCC70280.1 - 2e-06 26.9 9.0 2e-06 26.9 6.2 3.2 2 0 0 2 2 2 1 Yeast PIR protein repeat Macoilin PF09726.4 CCC70280.1 - 0.04 12.2 10.2 0.041 12.1 7.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Tmemb_cc2 PF10267.4 CCC70280.1 - 0.089 11.3 5.3 0.1 11.1 3.7 1.1 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2201_N PF13203.1 CCC70280.1 - 0.1 11.7 5.8 0.14 11.3 4.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain TFIIA PF03153.8 CCC70280.1 - 0.44 10.3 5.6 0.5 10.2 3.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DNA_pol_viral_N PF00242.12 CCC70280.1 - 0.65 8.9 9.9 0.8 8.6 6.8 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain CDC27 PF09507.5 CCC70280.1 - 1.7 7.8 10.0 1.9 7.5 6.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SRP1_TIP1 PF00660.12 CCC70281.1 - 3.4e-63 209.9 14.3 2.3e-20 72.3 0.5 4.1 3 0 0 3 3 3 3 Seripauperin and TIP1 family DUF257 PF03192.8 CCC70281.1 - 0.0047 16.2 0.0 23 4.1 0.0 3.2 3 0 0 3 3 3 3 Pyrococcus protein of unknown function, DUF257 HbrB PF08539.6 CCC70281.1 - 0.18 11.6 3.7 57 3.5 0.0 3.7 3 0 0 3 3 3 0 HbrB-like WSC PF01822.14 CCC70282.1 - 2.3e-12 46.6 14.7 2.3e-12 46.6 10.2 2.5 2 1 0 2 2 2 1 WSC domain Herpes_gE PF02480.11 CCC70282.1 - 0.0011 17.3 0.1 0.0011 17.3 0.1 1.5 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 CCC70282.1 - 0.0016 17.2 0.1 0.0025 16.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) DUF456 PF04306.8 CCC70282.1 - 0.01 15.8 0.1 0.017 15.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Bacteriocin_IIc PF10439.4 CCC70282.1 - 0.04 14.0 4.0 0.1 12.7 2.8 1.6 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 CCC70282.1 - 0.044 13.4 4.7 0.086 12.4 3.2 1.4 1 0 0 1 1 1 0 Glycine zipper Gly-zipper_OmpA PF13436.1 CCC70282.1 - 0.052 13.2 5.5 0.045 13.4 2.1 2.1 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Syndecan PF01034.15 CCC70282.1 - 0.073 12.7 0.6 0.15 11.7 0.4 1.5 1 0 0 1 1 1 0 Syndecan domain Colicin_V PF02674.11 CCC70282.1 - 0.074 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Colicin V production protein Gly-zipper_YMGG PF13441.1 CCC70282.1 - 0.16 11.5 4.0 0.28 10.7 2.8 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper DUF912 PF06024.7 CCC70282.1 - 0.39 10.7 1.5 0.79 9.8 0.0 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2408 PF10303.4 CCC70283.1 - 1.4e-75 251.8 22.8 5.8e-49 165.6 3.4 5.0 3 2 2 5 5 5 4 Protein of unknown function (DUF2408) Prominin PF05478.6 CCC70283.1 - 0.0022 15.6 12.5 0.12 9.8 9.1 2.1 2 0 0 2 2 2 2 Prominin PLAC9 PF15205.1 CCC70283.1 - 0.11 12.7 0.3 98 3.3 0.1 3.5 3 1 1 4 4 4 0 Placenta-specific protein 9 Adap_comp_sub PF00928.16 CCC70284.1 - 5.1e-91 304.3 2.7 7.1e-91 303.9 1.9 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 CCC70284.1 - 2e-05 24.3 1.7 4.6e-05 23.1 0.7 1.9 1 1 1 2 2 2 1 Clathrin adaptor complex small chain TPP1 PF10341.4 CCC70285.1 - 2.2e-27 95.0 0.1 2.9e-27 94.7 0.1 1.1 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD ETF_QO PF05187.8 CCC70286.1 - 1.8e-38 130.8 0.0 3e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 CCC70286.1 - 1.9e-09 36.8 0.4 0.00029 19.8 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCC70286.1 - 2.2e-08 34.0 0.0 5.7e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCC70286.1 - 2.7e-07 29.9 0.0 4.4e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 CCC70286.1 - 7.6e-07 28.3 0.2 0.00036 19.4 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 CCC70286.1 - 2.1e-06 27.9 0.0 3.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCC70286.1 - 6.3e-06 26.2 0.0 1.4e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 CCC70286.1 - 2.8e-05 22.7 0.2 0.00045 18.8 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 CCC70286.1 - 0.00013 22.3 0.3 0.27 11.6 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 CCC70286.1 - 0.00037 20.3 0.1 0.00071 19.3 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 CCC70286.1 - 0.00053 19.1 0.0 0.00077 18.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 CCC70286.1 - 0.00084 18.5 0.0 0.0015 17.6 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4_7 PF12838.2 CCC70286.1 - 0.0063 16.8 1.0 0.015 15.6 0.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Lycopene_cycl PF05834.7 CCC70286.1 - 0.01 14.7 0.2 0.014 14.3 0.1 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 CCC70286.1 - 0.032 13.1 0.0 0.055 12.3 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GMC_oxred_N PF00732.14 CCC70286.1 - 0.038 13.1 0.0 1.1 8.3 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Trp_halogenase PF04820.9 CCC70286.1 - 0.049 12.2 0.0 0.085 11.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Fer4_10 PF13237.1 CCC70286.1 - 0.14 11.9 0.7 0.27 11.0 0.5 1.4 1 0 0 1 1 1 0 4Fe-4S dicluster domain Cyclin_N PF00134.18 CCC70288.1 - 2.7e-27 94.8 2.2 7.6e-27 93.3 1.5 1.8 1 0 0 1 1 1 1 Cyclin, N-terminal domain PPR_3 PF13812.1 CCC70289.1 - 0.03 14.5 0.1 31 5.2 0.0 3.8 5 0 0 5 5 5 0 Pentatricopeptide repeat domain SOG2 PF10428.4 CCC70290.1 - 1.6e-115 386.3 22.4 1.6e-115 386.3 15.5 2.4 3 0 0 3 3 3 1 RAM signalling pathway protein LRR_4 PF12799.2 CCC70290.1 - 1.1e-16 60.0 21.8 4.5e-09 35.7 0.8 4.9 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCC70290.1 - 4e-16 58.4 26.6 8.4e-09 35.0 2.1 3.7 2 1 2 4 4 4 3 Leucine rich repeat LRR_1 PF00560.28 CCC70290.1 - 1.1e-09 36.9 19.6 0.077 13.0 0.1 7.7 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.1 CCC70290.1 - 3.6e-05 23.3 8.1 1.3 9.2 0.1 6.1 5 0 0 5 5 5 2 Leucine Rich repeat LRR_7 PF13504.1 CCC70290.1 - 0.00017 21.2 15.0 3.1 8.3 0.0 6.8 6 0 0 6 6 6 2 Leucine rich repeat SpecificRecomb PF10136.4 CCC70290.1 - 0.0046 15.0 0.3 0.0046 15.0 0.2 1.8 2 0 0 2 2 2 1 Site-specific recombinase PRD PF00874.15 CCC70290.1 - 0.042 13.9 2.5 0.16 12.1 0.9 2.5 2 0 0 2 2 2 0 PRD domain ADH_zinc_N PF00107.21 CCC70292.1 - 1.4e-12 47.2 0.0 2.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCC70292.1 - 1.2e-06 28.2 0.3 4e-05 23.3 0.2 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Pkinase PF00069.20 CCC70293.1 - 9.5e-66 221.5 0.0 1.3e-65 221.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC70293.1 - 2.2e-29 102.3 0.0 3.3e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 CCC70293.1 - 9.5e-16 57.6 0.1 8.6e-15 54.6 0.0 2.5 2 0 0 2 2 2 1 FHA domain Kdo PF06293.9 CCC70293.1 - 0.0085 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MNE1 PF13762.1 CCC70294.1 - 6.7e-13 48.9 10.4 1.8e-12 47.5 2.7 2.8 2 0 0 2 2 2 2 Mitochondrial splicing apparatus component AA_permease PF00324.16 CCC70296.1 - 1.1e-128 429.5 33.9 1.3e-128 429.3 23.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC70296.1 - 1.5e-26 92.9 38.1 2e-26 92.5 26.4 1.1 1 0 0 1 1 1 1 Amino acid permease DUF485 PF04341.7 CCC70296.1 - 5.8 6.7 0.0 5.8 6.7 0.0 4.5 6 0 0 6 6 6 0 Protein of unknown function, DUF485 DNA_pol_A PF00476.15 CCC70297.1 - 9.4e-109 363.5 0.0 1.6e-108 362.7 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A CorA PF01544.13 CCC70298.1 - 2.1e-09 36.8 4.6 3.5e-09 36.1 3.2 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF2312 PF10073.4 CCC70298.1 - 0.078 12.3 0.3 0.22 10.9 0.2 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) tRNA-synt_2c PF01411.14 CCC70299.1 - 1e-226 753.5 0.5 1.6e-226 752.9 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 CCC70299.1 - 3.2e-18 65.3 0.4 9.5e-18 63.8 0.2 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 CCC70299.1 - 1.3e-06 28.0 2.5 3.3e-06 26.7 1.8 1.7 1 0 0 1 1 1 1 DHHA1 domain UDP-g_GGTase PF06427.6 CCC70300.1 - 5e-10 39.0 0.2 1.3e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Fungal_trans PF04082.13 CCC70301.1 - 3.4e-35 121.1 1.9 3.4e-35 121.1 1.3 2.8 3 0 0 3 3 3 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC70301.1 - 2.9e-09 36.6 10.4 4.9e-09 35.9 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SWIRM PF04433.12 CCC70302.1 - 2.8e-13 49.7 0.0 6.1e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 SWIRM domain SHS2_Rpb7-N PF03876.12 CCC70303.1 - 5.3e-12 45.6 0.0 1.4e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GTP_EFTU PF00009.22 CCC70304.1 - 4.6e-32 110.9 0.0 4.6e-32 110.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 CCC70304.1 - 1.8e-21 76.0 0.0 5.7e-21 74.4 0.0 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 CCC70304.1 - 1.2e-12 47.7 3.7 1.2e-09 38.1 0.0 3.6 3 0 0 3 3 3 2 Elongation factor Tu domain 2 AAA_22 PF13401.1 CCC70304.1 - 0.026 14.6 0.2 0.17 11.9 0.1 2.4 1 1 0 1 1 1 0 AAA domain HLH PF00010.21 CCC70306.1 - 2.5e-20 71.8 0.1 8.9e-20 70.1 0.0 2.0 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF4611 PF15387.1 CCC70306.1 - 0.091 12.9 4.2 1.8 8.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) IMS PF00817.15 CCC70307.1 - 4.5e-28 97.9 0.0 8.7e-28 96.9 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family BRCT PF00533.21 CCC70307.1 - 1.5e-12 47.4 0.2 2.6e-11 43.5 0.1 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain IMS_C PF11799.3 CCC70307.1 - 3.7e-11 43.0 0.0 8.9e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain PTCB-BRCT PF12738.2 CCC70307.1 - 1e-07 31.6 0.0 1.1e-06 28.3 0.0 2.4 2 0 0 2 2 2 1 twin BRCT domain PK PF00224.16 CCC70308.1 - 4.6e-162 538.5 0.6 5.8e-162 538.1 0.4 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 CCC70308.1 - 7.5e-30 102.8 0.0 1.8e-29 101.6 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 CCC70308.1 - 4.2e-05 22.5 0.2 0.00012 21.0 0.1 1.7 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family ATP-synt_ab PF00006.20 CCC70309.1 - 6e-70 235.0 0.0 8.6e-70 234.5 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCC70309.1 - 5.2e-27 94.5 0.3 1.5e-26 93.0 0.2 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCC70309.1 - 1e-16 60.8 1.5 2.6e-16 59.5 1.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Tex_N PF09371.5 CCC70309.1 - 0.0049 16.1 0.0 0.011 15.0 0.0 1.5 1 0 0 1 1 1 1 Tex-like protein N-terminal domain HAS-barrel PF09378.5 CCC70309.1 - 0.011 15.6 0.5 0.028 14.3 0.3 1.8 1 0 0 1 1 1 0 HAS barrel domain AAA_25 PF13481.1 CCC70309.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cnd2 PF05786.9 CCC70310.1 - 1.6e-127 427.0 52.7 6.1e-126 421.7 36.6 2.0 1 1 0 1 1 1 1 Condensin complex subunit 2 ScpA_ScpB PF02616.9 CCC70310.1 - 0.042 13.4 8.0 1.5 8.3 1.3 2.9 2 2 0 2 2 2 0 ScpA/B protein 4HBT PF03061.17 CCC70311.1 - 5.5e-05 23.2 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Rox3 PF08633.5 CCC70312.1 - 1.6e-58 198.1 2.6 1.9e-58 198.0 1.8 1.0 1 0 0 1 1 1 1 Rox3 mediator complex subunit Ribosomal_L32e PF01655.13 CCC70313.1 - 4.9e-46 155.3 1.8 5.7e-46 155.1 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 DUF3437 PF11919.3 CCC70313.1 - 0.15 11.8 0.3 0.29 10.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) Aa_trans PF01490.13 CCC70314.1 - 2.7e-108 362.0 19.1 3.3e-108 361.7 13.2 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 CCC70314.1 - 2.5e-08 33.1 17.9 5.3e-08 32.0 12.4 1.6 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family tRNA_anti-like PF12869.2 CCC70314.1 - 0.054 12.9 0.8 0.17 11.3 0.0 2.2 2 0 0 2 2 2 0 tRNA_anti-like Abhydrolase_9_N PF15420.1 CCC70314.1 - 1.4 8.6 13.1 6.1 6.5 0.0 4.1 3 1 1 4 4 4 0 Alpha/beta-hydrolase family N-terminus PI3_PI4_kinase PF00454.22 CCC70315.1 - 5.9e-52 176.4 0.1 1.5e-51 175.1 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 CCC70315.1 - 9.9e-23 80.5 4.7 9.9e-23 80.5 3.2 2.9 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 CCC70315.1 - 5.7e-13 48.0 0.1 1.4e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 FATC domain Ribosomal_L14 PF00238.14 CCC70316.1 - 5.1e-31 106.9 0.0 5.7e-31 106.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e NT-C2 PF10358.4 CCC70317.1 - 2.4e-37 127.5 7.6 2.4e-37 127.5 5.3 2.4 2 1 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins PH PF00169.24 CCC70318.1 - 1e-12 48.1 0.1 7e-12 45.4 0.0 2.6 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.12 CCC70318.1 - 1.4e-12 47.2 0.0 3.3e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 CCC70318.1 - 2.7e-09 36.2 0.0 5.9e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCC70318.1 - 1.1e-08 34.4 0.0 3.1e-08 33.0 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SAM_1 PF00536.25 CCC70318.1 - 6.4e-07 29.4 0.0 1.7e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PH_11 PF15413.1 CCC70318.1 - 0.00023 21.3 0.0 0.00023 21.3 0.0 4.9 5 1 0 5 5 5 1 Pleckstrin homology domain SH3_2 PF07653.12 CCC70318.1 - 0.0003 20.2 0.0 0.00077 18.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 CCC70318.1 - 0.00099 19.1 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 Pleckstrin homology domain Ste50p-SAM PF09235.5 CCC70318.1 - 0.034 14.1 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 Ste50p, sterile alpha motif TPR_1 PF00515.23 CCC70319.1 - 5.2e-36 120.7 14.2 1.6e-09 36.9 0.1 8.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 CCC70319.1 - 3.8e-35 119.3 20.1 8.5e-13 47.7 0.6 6.7 4 1 4 8 8 8 5 TPR repeat TPR_2 PF07719.12 CCC70319.1 - 5.1e-34 113.4 15.0 3.8e-07 29.5 0.0 8.9 9 0 0 9 9 8 6 Tetratricopeptide repeat Apc3 PF12895.2 CCC70319.1 - 1.1e-24 86.4 29.9 3.7e-12 46.1 1.1 5.5 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCC70319.1 - 3.4e-24 82.7 13.1 7.6e-06 25.3 0.2 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 CCC70319.1 - 7.5e-22 77.4 0.0 3.6e-08 33.8 0.0 4.9 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCC70319.1 - 7.1e-20 70.7 10.3 1.7e-06 27.8 0.3 6.8 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCC70319.1 - 1.2e-15 56.5 0.0 0.012 16.1 0.1 6.8 2 1 5 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCC70319.1 - 2.5e-13 48.7 2.5 0.43 10.4 0.0 7.9 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_17 PF13431.1 CCC70319.1 - 3.2e-13 48.7 10.2 0.18 12.0 0.0 8.4 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_6 PF13174.1 CCC70319.1 - 3.8e-13 48.9 18.7 0.0021 18.3 0.0 9.2 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 CCC70319.1 - 4.5e-13 49.3 4.0 0.00011 22.5 0.0 5.8 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_9 PF13371.1 CCC70319.1 - 3.6e-07 29.9 0.3 0.00011 22.0 0.0 3.7 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCC70319.1 - 3.6e-07 29.5 1.7 0.0014 17.7 0.1 3.7 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_21 PF09976.4 CCC70319.1 - 0.0045 16.9 1.5 0.26 11.2 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCC70319.1 - 0.0052 16.6 9.7 1.6 8.7 0.1 5.6 6 0 0 6 6 5 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 CCC70319.1 - 0.0076 16.1 4.4 3.9 7.4 0.0 4.8 4 2 1 5 5 5 1 MIT (microtubule interacting and transport) domain Apc5 PF12862.2 CCC70319.1 - 0.011 15.5 4.9 0.064 13.1 0.7 4.0 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_10 PF13374.1 CCC70319.1 - 0.012 15.5 0.9 7.9 6.5 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.7 CCC70319.1 - 0.32 11.6 5.1 41 4.9 0.0 4.7 6 0 0 6 6 5 0 Sel1 repeat PAP2 PF01569.16 CCC70320.1 - 1.3e-12 47.5 7.1 1.3e-12 47.5 4.9 2.5 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 CCC70320.1 - 9.5e-05 21.9 7.0 9.5e-05 21.9 4.9 2.1 1 1 1 2 2 2 1 PAP2 superfamily Luteo_P1-P2 PF08467.5 CCC70320.1 - 0.043 12.6 2.3 0.063 12.0 1.6 1.1 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase ALG3 PF05208.8 CCC70321.1 - 1.3e-127 426.0 25.8 1.6e-127 425.7 17.9 1.1 1 0 0 1 1 1 1 ALG3 protein LisH PF08513.6 CCC70322.1 - 4.8e-06 26.1 0.1 9.4e-06 25.2 0.1 1.5 1 0 0 1 1 1 1 LisH GatB_N PF02934.10 CCC70324.1 - 6.7e-98 327.1 0.1 9.4e-98 326.6 0.1 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 CCC70324.1 - 1.9e-30 105.5 0.9 3.4e-30 104.7 0.6 1.4 1 0 0 1 1 1 1 GatB domain PurS PF02700.9 CCC70324.1 - 0.072 13.0 0.8 0.2 11.6 0.6 1.7 1 0 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Nucleoporin_C PF03177.9 CCC70325.1 - 3.6e-121 405.5 15.0 4.8e-121 405.1 10.4 1.2 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 CCC70325.1 - 9e-109 364.0 5.9 1.5e-108 363.3 4.1 1.4 1 0 0 1 1 1 1 Nup133 N terminal like Atg8 PF02991.11 CCC70326.1 - 2e-49 165.8 0.1 2.8e-49 165.3 0.1 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 CCC70326.1 - 2.5e-05 24.3 0.0 3.8e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 tRNA-synt_1 PF00133.17 CCC70327.1 - 1.7e-239 795.8 0.8 9.9e-239 793.3 0.1 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 CCC70327.1 - 3.2e-25 88.6 0.1 1.1e-24 86.9 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 CCC70327.1 - 8.8e-18 64.1 4.8 2.6e-06 26.3 0.6 4.7 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 CCC70327.1 - 0.001 18.2 0.0 0.003 16.7 0.0 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF1435 PF07256.7 CCC70327.1 - 0.1 12.5 0.0 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) HSP70 PF00012.15 CCC70328.1 - 7.9e-267 886.0 9.0 9e-267 885.8 6.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCC70328.1 - 1.7e-16 59.7 0.1 2.1e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CCC70328.1 - 0.00022 20.8 0.0 0.00049 19.7 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 CCC70328.1 - 0.0033 16.2 0.3 0.22 10.2 0.1 2.2 2 0 0 2 2 2 2 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 CCC70328.1 - 0.33 10.0 3.1 0.71 8.9 0.1 2.6 2 1 1 3 3 3 0 Hydantoinase/oxoprolinase Ribosomal_S8e PF01201.17 CCC70329.1 - 4.7e-50 169.1 2.8 5.4e-50 168.9 1.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S8e UQ_con PF00179.21 CCC70330.1 - 7.3e-29 99.9 0.1 1.1e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCC70330.1 - 0.004 17.0 0.2 0.009 15.9 0.1 1.6 1 0 0 1 1 1 1 RWD domain UCH PF00443.24 CCC70331.1 - 7e-71 238.4 13.1 1.6e-70 237.2 9.1 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC70331.1 - 7.4e-24 84.7 14.1 4.5e-21 75.5 0.6 3.0 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Fungal_trans PF04082.13 CCC70332.1 - 2.2e-25 89.0 3.4 4.3e-25 88.0 2.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC70332.1 - 1.1e-08 34.8 11.5 1.8e-08 34.1 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA PF00578.16 CCC70333.1 - 1.7e-32 111.6 0.0 2.3e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 CCC70333.1 - 9.6e-12 44.3 0.0 1.6e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 CCC70333.1 - 9e-10 38.2 0.0 1.3e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin Pribosyl_synth PF14572.1 CCC70333.1 - 0.073 12.8 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl synthetase-associated domain Kinesin PF00225.18 CCC70334.1 - 1.1e-107 359.6 1.1 1.1e-107 359.6 0.7 2.5 3 0 0 3 3 3 1 Kinesin motor domain Sel1 PF08238.7 CCC70335.1 - 1.3e-41 140.1 19.0 1.9e-08 34.6 0.2 7.9 7 0 0 7 7 7 7 Sel1 repeat Sec7 PF01369.15 CCC70336.1 - 8.6e-26 90.7 0.2 1.9e-25 89.6 0.2 1.6 1 0 0 1 1 1 1 Sec7 domain DUF3375 PF11855.3 CCC70336.1 - 0.099 11.3 0.0 0.2 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3375) Cmc1 PF08583.5 CCC70337.1 - 4.4e-17 61.6 6.4 6.7e-17 61.0 4.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 CCC70337.1 - 0.0061 16.4 2.0 1.1 9.2 0.1 2.3 2 0 0 2 2 2 2 CHCH domain HNOBA PF07701.9 CCC70337.1 - 0.068 12.3 0.3 0.078 12.1 0.2 1.1 1 0 0 1 1 1 0 Heme NO binding associated CBM_14 PF01607.19 CCC70337.1 - 0.15 11.9 0.4 0.23 11.4 0.3 1.2 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain ARD PF03079.9 CCC70337.1 - 0.25 11.2 1.4 0.3 11.0 1.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family NDUF_B7 PF05676.8 CCC70337.1 - 0.37 10.2 4.2 0.89 9.0 2.9 1.7 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) CCDC-167 PF15188.1 CCC70337.1 - 2.1 8.3 7.0 0.97 9.4 2.2 1.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 SEP PF08059.8 CCC70339.1 - 2.5e-26 91.7 0.2 6e-26 90.5 0.1 1.7 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 CCC70339.1 - 5e-17 61.7 0.1 9.2e-17 60.8 0.1 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CCC70339.1 - 3.2e-13 48.9 0.6 5.5e-13 48.2 0.4 1.4 1 0 0 1 1 1 1 UBA-like domain AHH PF14412.1 CCC70339.1 - 0.074 13.0 0.7 1 9.3 0.0 2.9 2 2 0 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Spindle_Spc25 PF08234.7 CCC70339.1 - 0.078 12.9 0.5 0.74 9.8 0.1 2.6 2 1 1 3 3 3 0 Chromosome segregation protein Spc25 PTH2 PF01981.11 CCC70340.1 - 2.9e-46 155.9 0.2 2.9e-46 155.9 0.1 1.4 2 0 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 PGA2 PF07543.7 CCC70340.1 - 0.087 12.6 2.4 0.14 11.9 1.7 1.3 1 0 0 1 1 1 0 Protein trafficking PGA2 Ycf1 PF05758.7 CCC70340.1 - 0.11 10.2 0.1 0.11 10.2 0.0 1.0 1 0 0 1 1 1 0 Ycf1 T2SM PF04612.7 CCC70340.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Nop25 PF09805.4 CCC70340.1 - 0.28 11.2 5.8 0.4 10.7 4.0 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2457 PF10446.4 CCC70340.1 - 1.3 7.7 10.3 1.8 7.1 7.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.7 CCC70340.1 - 1.6 7.8 8.5 2.3 7.2 5.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PP2C PF00481.16 CCC70342.1 - 5.3e-78 261.9 0.0 7.1e-78 261.5 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C TatD_DNase PF01026.16 CCC70343.1 - 4.2e-37 127.7 0.0 5.2e-37 127.4 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 CCC70343.1 - 0.077 12.5 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Amidohydrolase Myb_DNA-bind_6 PF13921.1 CCC70344.1 - 1.8e-10 40.7 5.8 1.8e-08 34.3 0.4 3.4 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCC70344.1 - 5.1e-07 29.6 4.0 2e-05 24.5 0.2 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 CCC70344.1 - 0.069 13.0 1.5 1.6 8.6 0.2 2.7 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain SelP_N PF04592.9 CCC70344.1 - 1.4 8.2 10.4 3.4 6.9 7.2 1.6 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MOZ_SAS PF01853.13 CCC70345.1 - 1.8e-75 252.3 1.3 3e-75 251.6 0.9 1.3 1 0 0 1 1 1 1 MOZ/SAS family UPF0564 PF10595.4 CCC70345.1 - 0.012 14.5 2.6 0.024 13.5 1.8 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 Pox_Ag35 PF03286.9 CCC70345.1 - 3.8 6.9 20.6 5 6.5 12.8 2.2 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Sec61_beta PF03911.11 CCC70346.1 - 2.9e-17 62.1 0.6 3.7e-17 61.8 0.4 1.1 1 0 0 1 1 1 1 Sec61beta family AAA_2 PF07724.9 CCC70347.1 - 0.041 13.7 0.2 0.055 13.3 0.1 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Ndc1_Nup PF09531.5 CCC70347.1 - 4.2 5.6 6.3 1.7 6.9 2.9 1.4 1 1 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MMR1 PF08505.5 CCC70348.1 - 3.6e-17 63.1 26.9 3.6e-17 63.1 18.6 3.7 2 1 0 2 2 2 1 Mitochondrial Myo2 receptor-related protein T2SM PF04612.7 CCC70348.1 - 2.8 7.7 4.4 17 5.1 0.2 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein M GerA PF03323.8 CCC70348.1 - 6 4.8 5.7 9 4.3 3.9 1.2 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Peroxin-13_N PF04088.8 CCC70349.1 - 2.6e-59 199.6 0.9 4.1e-59 199.0 0.7 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_9 PF14604.1 CCC70349.1 - 3.8e-08 32.7 0.0 6e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 CCC70349.1 - 1.1e-07 31.0 0.0 2e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 CCC70349.1 - 3.4e-06 26.4 0.0 6.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 CCC70349.1 - 0.0075 16.4 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Bacterial SH3 domain eIF3_subunit PF08597.5 CCC70350.1 - 1.6e-55 188.3 17.0 5e-55 186.7 11.8 1.6 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit PRELI PF04707.9 CCC70351.1 - 8e-45 152.2 0.4 9.7e-45 151.9 0.3 1.0 1 0 0 1 1 1 1 PRELI-like family NMT PF01233.14 CCC70353.1 - 2.2e-83 277.7 1.5 7.2e-83 276.0 0.1 2.2 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 CCC70353.1 - 3.4e-74 248.3 0.3 7.2e-74 247.2 0.2 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_3 PF13302.1 CCC70353.1 - 0.00017 21.8 0.1 0.038 14.1 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCC70353.1 - 0.00035 20.4 0.0 0.0021 17.8 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF1413 PF07205.6 CCC70353.1 - 0.023 14.2 2.3 0.23 11.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) Acetyltransf_7 PF13508.1 CCC70353.1 - 0.05 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.27 CCC70354.1 - 1.2e-13 50.3 9.2 6.5e-06 25.8 0.2 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 CCC70354.1 - 0.00027 19.2 0.8 0.0072 14.5 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 CCC70354.1 - 0.0074 16.5 0.1 0.99 9.7 0.0 3.7 5 0 0 5 5 5 1 PQQ-like domain POC1 PF10450.4 CCC70355.1 - 4.7e-91 304.3 1.6 5.3e-91 304.1 1.1 1.0 1 0 0 1 1 1 1 POC1 chaperone Prefoldin_2 PF01920.15 CCC70356.1 - 9.9e-25 86.3 12.1 1.1e-24 86.1 8.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 CCC70356.1 - 0.00065 19.4 4.6 0.00092 18.9 3.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit MIP-T3 PF10243.4 CCC70356.1 - 0.012 14.1 4.1 0.019 13.4 2.8 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AAA_13 PF13166.1 CCC70356.1 - 0.017 13.6 5.7 0.019 13.4 3.9 1.0 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 CCC70356.1 - 0.03 13.2 5.7 0.035 13.0 4.0 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Prefoldin PF02996.12 CCC70356.1 - 0.04 13.5 8.8 0.17 11.5 6.1 1.9 1 1 0 1 1 1 0 Prefoldin subunit Spc24 PF08286.6 CCC70356.1 - 0.045 13.4 8.0 0.68 9.6 0.3 2.0 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 End3 PF12761.2 CCC70356.1 - 0.06 12.9 7.6 0.065 12.8 5.2 1.0 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 HrpB7 PF09486.5 CCC70356.1 - 0.062 13.2 0.6 0.64 9.9 0.1 1.9 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) FliD_C PF07195.7 CCC70356.1 - 0.075 12.3 1.3 0.093 12.0 0.9 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF342 PF03961.8 CCC70356.1 - 0.1 10.9 8.3 0.11 10.8 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF883 PF05957.8 CCC70356.1 - 0.13 12.6 0.9 0.31 11.4 0.2 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CENP-F_leu_zip PF10473.4 CCC70356.1 - 0.18 11.6 12.7 1 9.1 0.9 2.0 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WASH-7_N PF14745.1 CCC70356.1 - 0.25 9.4 4.8 0.29 9.2 3.3 1.0 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal Bacillus_HBL PF05791.6 CCC70356.1 - 0.27 10.5 5.8 0.1 11.9 1.1 1.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF1192 PF06698.6 CCC70356.1 - 0.27 11.0 2.9 0.2 11.4 0.5 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF1192) YgaB PF14182.1 CCC70356.1 - 0.35 11.1 15.8 0.26 11.5 6.1 2.7 1 1 1 2 2 2 0 YgaB-like protein AHH PF14412.1 CCC70356.1 - 0.39 10.7 1.7 0.53 10.3 1.2 1.4 1 1 0 1 1 1 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH DUF4201 PF13870.1 CCC70356.1 - 0.45 9.9 11.1 0.1 12.0 2.5 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4201) DUF4164 PF13747.1 CCC70356.1 - 0.46 10.6 5.8 1.2 9.2 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF1640 PF07798.6 CCC70356.1 - 0.55 10.2 7.4 1.4 8.9 5.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Macoilin PF09726.4 CCC70356.1 - 0.58 8.3 7.7 0.68 8.1 5.4 1.0 1 0 0 1 1 1 0 Transmembrane protein DMPK_coil PF08826.5 CCC70356.1 - 0.66 9.9 10.1 0.45 10.4 0.9 2.6 2 1 0 2 2 2 0 DMPK coiled coil domain like DUF2247 PF10004.4 CCC70356.1 - 0.69 9.6 4.0 0.79 9.4 2.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) DUF641 PF04859.7 CCC70356.1 - 0.74 9.5 9.5 0.31 10.7 0.6 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Seryl_tRNA_N PF02403.17 CCC70356.1 - 1.2 9.2 11.3 1.2 9.1 4.2 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain zf-C4H2 PF10146.4 CCC70356.1 - 1.2 9.0 7.7 1.5 8.7 5.3 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Cortex-I_coil PF09304.5 CCC70356.1 - 1.3 9.1 10.9 8.2 6.5 7.5 2.0 1 1 0 1 1 1 0 Cortexillin I, coiled coil THOC7 PF05615.8 CCC70356.1 - 1.5 9.0 12.0 1.9 8.7 0.6 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 DivIC PF04977.10 CCC70356.1 - 1.8 8.1 8.3 1.1 8.8 1.1 2.4 2 0 0 2 2 2 0 Septum formation initiator FliJ PF02050.11 CCC70356.1 - 1.8 8.6 11.2 1.5 8.8 2.3 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein EAP30 PF04157.11 CCC70356.1 - 2.3 7.3 7.3 1.8 7.6 0.3 2.0 1 1 1 2 2 2 0 EAP30/Vps36 family IncA PF04156.9 CCC70356.1 - 2.9 7.4 13.8 8.1 5.9 1.5 1.8 1 1 0 1 1 1 0 IncA protein Snf7 PF03357.16 CCC70356.1 - 2.9 7.2 11.1 0.11 11.8 2.2 2.1 2 1 0 2 2 2 0 Snf7 DUF1664 PF07889.7 CCC70356.1 - 3.2 7.5 6.1 2.2 8.1 0.8 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.14 CCC70356.1 - 3.8 6.9 11.9 6.5 6.2 8.3 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Med9 PF07544.8 CCC70356.1 - 4.7 7.0 9.5 1.2 8.8 2.8 2.2 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ATG16 PF08614.6 CCC70356.1 - 5 6.8 10.2 6.1 6.6 2.2 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) ATP-synt_E_2 PF08112.6 CCC70356.1 - 5.8 7.0 8.5 0.53 10.3 1.7 2.2 2 1 0 2 2 2 0 ATP synthase epsilon subunit APG6 PF04111.7 CCC70356.1 - 6.1 5.7 10.1 4.7 6.1 6.0 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 ADIP PF11559.3 CCC70356.1 - 6.4 6.6 10.7 19 5.1 7.4 1.7 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding Occludin_ELL PF07303.8 CCC70356.1 - 7.1 7.4 7.7 11 6.8 0.6 2.1 1 1 0 2 2 2 0 Occludin homology domain GrpE PF01025.14 CCC70356.1 - 7.2 6.1 10.7 2.1 7.8 2.6 2.0 1 1 0 2 2 2 0 GrpE DUF4200 PF13863.1 CCC70356.1 - 8.8 6.2 14.4 5.9 6.8 4.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) COQ9 PF08511.6 CCC70357.1 - 1.7e-20 72.3 0.4 3.1e-20 71.4 0.3 1.4 1 0 0 1 1 1 1 COQ9 INTS5_C PF14838.1 CCC70357.1 - 0.021 13.1 0.0 0.029 12.6 0.0 1.1 1 0 0 1 1 1 0 Integrator complex subunit 5 C-terminus zf-Mss51 PF13824.1 CCC70358.1 - 4.3e-20 71.3 1.0 2.1e-19 69.1 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger of mitochondrial splicing suppressor 51 YL1_C PF08265.6 CCC70358.1 - 0.0015 18.0 0.0 0.0034 16.8 0.0 1.6 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Heme_oxygenase PF01126.15 CCC70359.1 - 3.5e-13 49.5 1.0 1.6e-12 47.4 0.7 2.1 1 1 0 1 1 1 1 Heme oxygenase DUF4380 PF14315.1 CCC70359.1 - 0.011 14.8 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4380) DUF910 PF06014.6 CCC70359.1 - 0.03 14.2 0.8 0.074 12.9 0.6 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) Ribosomal_S18 PF01084.15 CCC70360.1 - 1.1e-18 66.7 0.0 2.1e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Ofd1_CTDD PF10637.4 CCC70361.1 - 1.6e-84 283.2 6.5 1.1e-79 267.2 3.3 2.7 2 1 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 CCC70361.1 - 3.7e-16 59.4 0.1 1.4e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Complex1_LYR_1 PF13232.1 CCC70362.1 - 2.4e-17 62.8 1.5 3.1e-17 62.5 1.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 CCC70362.1 - 2e-15 56.3 1.3 2.6e-15 55.9 0.9 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF1851 PF08906.6 CCC70362.1 - 0.045 13.7 0.1 0.075 13.0 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1851) DnaJ-X PF14308.1 CCC70363.1 - 8.6e-60 201.5 8.9 8.6e-60 201.5 6.2 1.5 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 CCC70363.1 - 3.3e-26 90.7 0.1 3.3e-26 90.7 0.1 2.6 3 0 0 3 3 3 1 DnaJ domain Metal_resist PF13801.1 CCC70363.1 - 0.12 12.3 0.4 2.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Heavy-metal resistance PRKCSH-like PF12999.2 CCC70363.1 - 3.2 7.2 5.1 12 5.3 1.3 2.7 3 0 0 3 3 3 0 Glucosidase II beta subunit-like eIF3g PF12353.3 CCC70364.1 - 0.013 15.4 1.8 0.028 14.3 1.2 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G Arrestin_C PF02752.17 CCC70367.1 - 2.5e-15 56.7 0.4 2.5e-15 56.7 0.3 3.4 3 1 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain Got1 PF04178.7 CCC70368.1 - 1.8e-30 105.4 19.9 2.5e-30 104.9 13.8 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF2333 PF10095.4 CCC70368.1 - 0.033 12.8 0.4 0.048 12.3 0.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) HLH PF00010.21 CCC70369.1 - 7e-12 44.8 0.1 1.5e-11 43.8 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain WD40 PF00400.27 CCC70370.1 - 0.89 9.5 4.1 34 4.5 0.1 3.8 4 0 0 4 4 4 0 WD domain, G-beta repeat zf-RING_2 PF13639.1 CCC70370.1 - 1.2 9.0 11.1 1.5 8.7 2.8 3.1 3 0 0 3 3 3 0 Ring finger domain Pkinase PF00069.20 CCC70371.1 - 2.4e-63 213.6 0.0 6e-63 212.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC70371.1 - 4.5e-35 120.9 0.0 1.1e-34 119.7 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 CCC70371.1 - 5.9e-31 106.0 10.6 6.4e-16 57.8 2.1 2.7 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 CCC70371.1 - 1.3e-19 69.6 36.8 1.4e-10 40.7 10.2 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 CCC70371.1 - 5.4e-12 46.0 2.2 5.4e-12 46.0 1.5 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCC70371.1 - 0.0015 17.5 0.4 0.0059 15.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like zf-tcix PF14952.1 CCC70371.1 - 2.2 7.6 10.9 0.52 9.6 1.2 2.7 1 1 1 2 2 2 0 Putative treble-clef, zinc-finger, Zn-binding Lgl_C PF08596.5 CCC70372.1 - 1.2e-141 471.8 0.1 4.1e-141 470.0 0.0 1.9 2 0 0 2 2 2 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 CCC70372.1 - 0.0058 16.4 1.3 12 6.0 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat Ala_racemase_C PF00842.16 CCC70372.1 - 0.037 13.4 0.1 0.1 12.0 0.0 1.7 1 0 0 1 1 1 0 Alanine racemase, C-terminal domain Cid2 PF09774.4 CCC70373.1 - 7.3e-29 100.8 5.6 1.3e-28 100.0 3.9 1.4 1 0 0 1 1 1 1 Caffeine-induced death protein 2 AIM24 PF01987.12 CCC70374.1 - 7.9e-11 41.8 0.0 7.7e-10 38.5 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial biogenesis AIM24 Gemini_AL1_M PF08283.6 CCC70374.1 - 0.14 12.0 0.9 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Geminivirus rep protein central domain NuA4 PF09340.5 CCC70375.1 - 2.1e-24 84.9 1.4 2.1e-24 84.9 1.0 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 DUF972 PF06156.8 CCC70375.1 - 0.023 15.0 4.0 0.023 15.0 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Phage_prot_Gp6 PF05133.9 CCC70375.1 - 0.023 13.2 0.3 0.59 8.6 0.0 2.0 2 0 0 2 2 2 0 Phage portal protein, SPP1 Gp6-like DivIC PF04977.10 CCC70375.1 - 0.39 10.2 15.2 1.1 8.8 0.7 2.1 2 0 0 2 2 2 0 Septum formation initiator IncA PF04156.9 CCC70375.1 - 0.44 10.1 16.2 1.4 8.4 4.1 2.1 2 0 0 2 2 2 0 IncA protein Pinin_SDK_memA PF04696.8 CCC70375.1 - 0.72 9.4 10.3 0.38 10.3 2.0 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region Selenoprotein_S PF06936.6 CCC70375.1 - 1.1 8.7 5.2 0.34 10.4 0.7 1.9 2 0 0 2 2 2 0 Selenoprotein S (SelS) Tropomyosin_1 PF12718.2 CCC70375.1 - 1.3 8.8 15.0 0.26 11.1 5.5 2.1 2 0 0 2 2 2 0 Tropomyosin like DUF904 PF06005.7 CCC70375.1 - 2.2 8.6 12.1 0.43 10.9 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) YlqD PF11068.3 CCC70375.1 - 3 7.9 12.2 1.3 9.0 2.7 2.1 2 0 0 2 2 2 0 YlqD protein DUF2968 PF11180.3 CCC70375.1 - 3.4 7.0 10.4 2.1 7.7 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) APG6 PF04111.7 CCC70375.1 - 4.6 6.1 9.0 2.4 7.1 2.2 2.0 2 0 0 2 2 2 0 Autophagy protein Apg6 Spc42p PF11544.3 CCC70376.1 - 0.069 13.0 3.2 0.11 12.4 0.9 2.4 2 0 0 2 2 2 0 Spindle pole body component Spc42p PCI PF01399.22 CCC70377.1 - 8.2e-07 29.2 0.1 1.9e-06 28.0 0.1 1.6 1 0 0 1 1 1 1 PCI domain AAL_decarboxy PF03306.8 CCC70377.1 - 0.043 12.8 0.0 0.074 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase Yeast-kill-tox PF09207.6 CCC70377.1 - 0.056 13.8 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 Yeast killer toxin YmgB PF10798.3 CCC70377.1 - 0.1 12.4 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR TPR_2 PF07719.12 CCC70377.1 - 0.11 12.4 0.1 18 5.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Tmemb_14 PF03647.8 CCC70379.1 - 3.5e-12 46.5 3.0 3.7e-12 46.4 2.1 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF3096 PF11295.3 CCC70379.1 - 3.5 7.2 6.7 31 4.1 4.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3096) AA_kinase PF00696.23 CCC70381.1 - 3.8e-40 137.9 0.0 5.8e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 CCC70381.1 - 2.2e-14 52.5 0.3 6.1e-08 31.9 0.1 3.0 3 0 0 3 3 3 2 ACT domain ACT_7 PF13840.1 CCC70381.1 - 9.3e-09 34.6 1.9 1.9e-06 27.3 0.2 2.5 2 0 0 2 2 2 2 ACT domain Mito_carr PF00153.22 CCC70382.1 - 5.1e-47 157.5 3.3 2.9e-16 58.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ABC_membrane PF00664.18 CCC70383.1 - 0.074 12.4 0.3 0.074 12.4 0.2 1.0 1 0 0 1 1 1 0 ABC transporter transmembrane region Vma12 PF11712.3 CCC70383.1 - 0.1 12.2 0.7 0.11 12.2 0.5 1.0 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CBM_21 PF03370.8 CCC70384.1 - 9.3e-30 102.9 0.2 3.7e-29 100.9 0.2 2.0 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit HisG PF01634.13 CCC70385.1 - 5e-54 182.2 0.1 7.6e-54 181.6 0.1 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 CCC70385.1 - 6.6e-29 99.6 0.0 1e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 HisG, C-terminal domain Transp_cyt_pur PF02133.10 CCC70386.1 - 3.7e-89 299.2 35.4 4.3e-89 299.0 24.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 CCC70387.1 - 2.2e-94 316.5 35.5 2.5e-94 316.3 24.6 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Transp_cyt_pur PF02133.10 CCC70388.1 - 5.3e-75 252.6 37.1 6.2e-75 252.4 25.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ketoacyl-synt PF00109.21 CCC70389.1 - 2.5e-53 181.1 0.0 3.5e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 CCC70389.1 - 3.2e-31 107.6 0.0 5.5e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 CCC70389.1 - 0.012 14.6 0.1 0.024 13.5 0.1 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain HD_2 PF12917.2 CCC70389.1 - 0.054 13.2 0.0 0.12 12.1 0.0 1.5 1 1 0 1 1 1 0 HD containing hydrolase-like enzyme Sad1_UNC PF07738.8 CCC70389.1 - 0.061 13.1 0.0 3.4 7.4 0.0 2.4 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal Transp_cyt_pur PF02133.10 CCC70390.1 - 5.2e-97 325.1 38.1 6e-97 324.9 26.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Sugar_tr PF00083.19 CCC70391.1 - 1.1e-164 548.3 36.4 1.3e-164 548.1 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC70391.1 - 1.8e-31 109.1 42.9 4.1e-27 94.8 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCC70391.1 - 0.00097 17.3 3.1 0.00097 17.3 2.2 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.1 CCC70391.1 - 7.1 4.9 45.0 0.015 13.7 0.9 3.5 4 1 0 4 4 4 0 MFS/sugar transport protein Cyclin PF08613.6 CCC70392.1 - 2.5e-38 131.8 8.2 4.3e-38 131.0 2.9 2.6 2 1 0 2 2 2 1 Cyclin Sugar_tr PF00083.19 CCC70393.1 - 0.14 10.7 0.0 0.17 10.4 0.0 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter Ribonuc_L-PSP PF01042.16 CCC70394.1 - 5.8e-42 142.2 1.1 6.5e-42 142.1 0.8 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Ribosomal_L34e PF01199.13 CCC70395.1 - 5.2e-37 125.9 4.0 5.2e-37 125.9 2.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e EndIII_4Fe-2S PF10576.4 CCC70395.1 - 0.27 11.4 2.0 0.53 10.5 0.1 2.3 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Transp_cyt_pur PF02133.10 CCC70396.1 - 1e-74 251.7 37.9 1.2e-74 251.5 26.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF619 PF04768.8 CCC70397.1 - 1.4e-53 180.7 0.5 3.1e-53 179.6 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 CCC70397.1 - 6.6e-30 103.9 0.0 1.4e-29 102.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 CCC70397.1 - 9.6e-18 64.5 0.0 1.7e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 CCC70397.1 - 0.015 15.2 0.0 0.046 13.6 0.0 1.9 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus U1snRNP70_N PF12220.3 CCC70398.1 - 5.9e-19 68.1 1.9 1.1e-18 67.3 1.3 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 CCC70398.1 - 2.4e-17 62.3 0.0 5e-17 61.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC70398.1 - 2.9e-13 49.5 0.0 6.5e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC70398.1 - 4e-05 23.3 0.1 7.4e-05 22.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_M15_3 PF08291.6 CCC70398.1 - 0.14 11.9 1.1 0.39 10.5 0.8 1.7 1 0 0 1 1 1 0 Peptidase M15 zf-RING_4 PF14570.1 CCC70399.1 - 5.9e-20 70.5 13.5 1.1e-19 69.7 9.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 CCC70399.1 - 1.3e-07 31.2 4.1 2.2e-07 30.5 0.3 2.8 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 CCC70399.1 - 1.4e-06 27.7 0.5 1.4e-06 27.7 0.4 2.7 3 0 0 3 3 3 1 Rtf2 RING-finger RRM_1 PF00076.17 CCC70399.1 - 3e-06 26.7 0.1 6.5e-05 22.4 0.1 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 CCC70399.1 - 1.4e-05 24.6 7.0 3.1e-05 23.5 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.6 CCC70399.1 - 4.6e-05 23.1 2.7 0.00011 21.9 1.9 1.6 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) RRM_6 PF14259.1 CCC70399.1 - 0.0012 18.7 0.0 0.0034 17.3 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 CCC70399.1 - 0.0024 17.6 9.2 0.0049 16.6 6.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCC70399.1 - 0.0077 15.8 10.9 0.017 14.7 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PocR PF10114.4 CCC70399.1 - 0.014 14.5 1.6 0.3 10.2 0.5 2.6 2 0 0 2 2 2 0 Sensory domain found in PocR SET_assoc PF11767.3 CCC70399.1 - 0.022 14.0 0.0 0.063 12.5 0.0 1.7 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated zf-UDP PF14569.1 CCC70399.1 - 0.056 13.2 5.2 0.13 12.0 3.6 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-RING_5 PF14634.1 CCC70399.1 - 0.17 11.5 9.7 0.34 10.6 6.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCC70399.1 - 0.72 9.9 11.2 1.5 8.8 7.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCC70399.1 - 0.92 9.4 10.7 13 5.8 7.4 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Peptidase_S49_N PF08496.5 CCC70399.1 - 6.1 6.6 6.3 0.56 9.9 0.2 2.3 3 0 0 3 3 3 0 Peptidase family S49 N-terminal DUF2578 PF10843.3 CCC70400.1 - 4.6e-55 186.3 14.5 5.2e-55 186.1 10.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2578) GerPC PF10737.4 CCC70400.1 - 0.077 12.7 2.5 0.084 12.6 0.3 1.9 2 0 0 2 2 2 0 Spore germination protein GerPC DUF3942 PF13078.1 CCC70400.1 - 1.6 8.8 6.0 0.57 10.2 2.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3942) ICL PF00463.16 CCC70401.1 - 1.6e-273 907.6 1.6 1.9e-273 907.4 1.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 CCC70401.1 - 2.1e-11 43.4 0.0 8.9e-11 41.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Vhr1 PF04001.8 CCC70402.1 - 3e-48 161.6 3.9 5.6e-48 160.8 2.7 1.4 1 0 0 1 1 1 1 Transcription factor Vhr1 HAD_2 PF13419.1 CCC70403.1 - 2.5e-11 44.0 0.0 3.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC70403.1 - 2.8e-06 27.8 0.0 4.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCC70403.1 - 3e-06 26.8 0.0 5.8e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CCC70403.1 - 0.061 13.4 0.0 0.085 13.0 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase P16-Arc PF04699.9 CCC70404.1 - 3.7e-50 169.8 0.0 4.1e-50 169.7 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Ribonuc_red_lgC PF02867.10 CCC70405.1 - 1.7e-214 713.3 0.0 2.2e-214 712.9 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 CCC70405.1 - 7.6e-22 76.9 0.0 1.8e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 CCC70405.1 - 1.5e-17 63.7 0.0 7.6e-17 61.5 0.0 2.3 1 0 0 1 1 1 1 ATP cone domain Sec6 PF06046.8 CCC70406.1 - 3.8e-156 520.4 15.5 3.8e-156 520.4 10.8 1.5 2 0 0 2 2 2 1 Exocyst complex component Sec6 Tctex-1 PF03645.8 CCC70407.1 - 2.8e-09 36.7 0.1 3.2e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 Tctex-1 family DUF202 PF02656.10 CCC70408.1 - 6.9e-14 51.8 1.9 6.9e-14 51.8 1.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) LHC PF00556.15 CCC70408.1 - 0.0053 16.5 0.2 0.018 14.8 0.1 1.9 1 0 0 1 1 1 1 Antenna complex alpha/beta subunit DUF2207 PF09972.4 CCC70408.1 - 8.3 4.8 6.0 17 3.8 4.2 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Aldedh PF00171.17 CCC70409.1 - 2.1e-184 613.1 0.6 2.4e-184 612.9 0.4 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_S24e PF01282.14 CCC70410.1 - 7.1e-35 118.6 0.2 1.1e-34 118.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e Yos1 PF08571.5 CCC70411.1 - 5.3e-30 103.3 1.7 5.9e-30 103.2 1.2 1.0 1 0 0 1 1 1 1 Yos1-like Statherin PF03875.8 CCC70411.1 - 0.13 12.1 0.9 0.25 11.2 0.6 1.5 1 1 0 1 1 1 0 Statherin Y_phosphatase PF00102.22 CCC70412.1 - 2.4e-51 174.3 0.5 2.4e-51 174.3 0.3 2.0 3 0 0 3 3 3 1 Protein-tyrosine phosphatase Rhodanese PF00581.15 CCC70412.1 - 1.2e-12 48.1 0.1 2.6e-11 43.8 0.0 3.0 3 1 0 3 3 3 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 CCC70412.1 - 0.015 15.5 0.0 0.047 13.9 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 CCC70412.1 - 0.039 13.5 0.0 0.2 11.2 0.0 2.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain gp32 PF08804.5 CCC70413.1 - 0.078 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 gp32 DNA binding protein like PPR_2 PF13041.1 CCC70414.1 - 8.4e-15 54.4 1.1 4.4e-09 36.1 0.1 3.3 2 1 1 3 3 3 2 PPR repeat family Peptidase_M24 PF00557.19 CCC70415.1 - 3.1e-50 170.6 0.0 4.2e-50 170.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 CCC70415.1 - 5.7e-31 106.6 0.1 2.3e-30 104.6 0.0 2.0 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain DUF4611 PF15387.1 CCC70416.1 - 0.66 10.1 3.0 0.28 11.3 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) APH PF01636.18 CCC70417.1 - 2e-08 34.2 0.0 5.7e-08 32.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Sulfatase_C PF14707.1 CCC70417.1 - 0.027 14.7 0.1 0.096 12.9 0.1 1.9 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase 2-Hacid_dh_C PF02826.14 CCC70418.1 - 3e-53 179.6 0.0 4.7e-53 178.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 CCC70418.1 - 1e-37 128.5 0.1 1.3e-37 128.2 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 CCC70418.1 - 2.3e-05 24.2 0.1 5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 CCC70418.1 - 8.8e-05 22.3 0.3 0.00021 21.1 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Acetyltransf_1 PF00583.19 CCC70418.1 - 0.007 16.3 0.0 0.057 13.4 0.0 2.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family ACT PF01842.20 CCC70418.1 - 0.014 14.8 0.0 0.042 13.3 0.0 1.8 1 0 0 1 1 1 0 ACT domain IlvN PF07991.7 CCC70418.1 - 0.019 14.3 0.1 0.04 13.2 0.1 1.5 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF4367 PF14285.1 CCC70418.1 - 0.025 13.9 0.3 0.057 12.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4367) XdhC_C PF13478.1 CCC70418.1 - 0.038 14.2 0.0 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain Helicase_C PF00271.26 CCC70418.1 - 0.071 12.9 0.1 1.1 9.1 0.0 2.6 1 1 1 2 2 2 0 Helicase conserved C-terminal domain 3HCDH_N PF02737.13 CCC70418.1 - 0.13 11.8 0.7 0.86 9.2 0.4 2.1 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PC_rep PF01851.17 CCC70419.1 - 2.3e-37 125.1 20.0 3.5e-06 26.9 0.3 10.7 10 0 0 10 10 10 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 CCC70419.1 - 1.2e-15 57.5 7.0 1.4e-12 47.7 0.1 5.1 3 1 2 6 6 6 1 HEAT repeats HEAT_EZ PF13513.1 CCC70419.1 - 3.6e-09 36.8 3.6 0.032 14.7 0.1 5.4 4 2 2 6 6 6 2 HEAT-like repeat HEAT PF02985.17 CCC70419.1 - 3.7e-08 32.7 3.2 1.2 9.3 0.0 5.8 6 0 0 6 6 6 3 HEAT repeat Apc3 PF12895.2 CCC70419.1 - 0.002 18.2 1.1 0.91 9.7 0.1 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Arm PF00514.18 CCC70419.1 - 0.0021 17.8 0.5 19 5.2 0.0 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.1 CCC70419.1 - 0.0077 16.1 0.4 0.1 12.5 0.0 3.1 3 1 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 ERAP1_C PF11838.3 CCC70419.1 - 0.012 14.9 1.1 0.19 10.9 0.0 3.0 4 0 0 4 4 4 0 ERAP1-like C-terminal domain Telomere_reg-2 PF10193.4 CCC70419.1 - 0.47 10.7 5.7 22 5.3 0.0 3.7 3 1 0 3 3 3 0 Telomere length regulation protein NARP1 PF12569.3 CCC70419.1 - 5.6 5.5 14.7 12 4.5 10.2 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BING4CT PF08149.6 CCC70420.1 - 8.4e-37 124.5 0.0 2.7e-35 119.7 0.0 3.0 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 CCC70420.1 - 6e-05 22.7 0.0 0.00076 19.2 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat HIT PF01230.18 CCC70421.1 - 6.6e-19 68.2 0.0 9.7e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 CCC70421.1 - 4.2e-06 26.9 1.7 1.1e-05 25.6 0.4 2.1 1 1 1 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 CCC70421.1 - 0.019 14.6 0.6 0.04 13.5 0.4 1.7 1 1 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 FAD-oxidase_C PF02913.14 CCC70422.1 - 4e-59 199.9 0.0 1.2e-58 198.3 0.0 1.7 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCC70422.1 - 3.3e-31 107.5 0.5 5.4e-31 106.9 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain zf-CCHC PF00098.18 CCC70426.1 - 0.001 18.8 4.3 0.001 18.8 3.0 2.2 2 0 0 2 2 2 1 Zinc knuckle Tox-SGS PF15651.1 CCC70426.1 - 0.078 12.7 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin zf-CCHC_5 PF14787.1 CCC70426.1 - 0.55 9.7 12.0 1.7 8.1 1.6 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.1 CCC70426.1 - 0.81 9.4 4.3 0.35 10.6 0.3 2.1 2 0 0 2 2 2 0 Zinc knuckle IBR PF01485.16 CCC70426.1 - 5.9 6.8 11.0 5.6 6.9 2.0 2.4 2 0 0 2 2 2 0 IBR domain GET2 PF08690.5 CCC70427.1 - 1.2e-86 290.7 5.6 2.9e-86 289.4 3.9 1.5 1 1 0 1 1 1 1 GET complex subunit GET2 AAA PF00004.24 CCC70428.1 - 5.1e-99 327.6 0.0 3e-48 163.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCC70428.1 - 2.1e-14 53.8 0.0 3.3e-07 30.3 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 CCC70428.1 - 6.9e-14 51.4 0.0 1e-05 24.7 0.0 3.1 3 2 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCC70428.1 - 2.9e-12 46.9 0.0 0.00033 20.7 0.0 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 CCC70428.1 - 4.9e-12 45.7 2.6 3.9e-06 26.6 0.1 4.1 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCC70428.1 - 1.2e-11 44.9 0.7 0.00065 19.8 0.1 4.0 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CCC70428.1 - 1.6e-11 44.2 0.0 5.7e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 CCC70428.1 - 4.1e-11 43.7 0.0 0.00086 20.1 0.0 3.1 3 1 0 3 3 2 2 AAA domain TIP49 PF06068.8 CCC70428.1 - 1.4e-09 37.2 0.1 0.00073 18.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_14 PF13173.1 CCC70428.1 - 1.6e-08 34.5 0.0 0.0025 17.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 CCC70428.1 - 4.9e-08 32.5 0.1 0.0049 16.2 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 CCC70428.1 - 7.4e-08 32.0 6.8 0.0054 16.1 0.6 4.2 2 2 1 3 3 3 2 AAA domain RNA_helicase PF00910.17 CCC70428.1 - 8.8e-08 32.2 0.0 0.0048 17.0 0.0 2.9 3 0 0 3 3 2 2 RNA helicase Mg_chelatase PF01078.16 CCC70428.1 - 1.4e-07 30.9 0.5 0.015 14.4 0.0 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 CCC70428.1 - 1.5e-07 30.6 0.0 0.0061 15.6 0.0 3.0 3 1 0 3 3 2 2 Zeta toxin AAA_19 PF13245.1 CCC70428.1 - 1.6e-07 30.9 2.2 0.013 15.1 0.0 3.0 3 0 0 3 3 2 2 Part of AAA domain KaiC PF06745.8 CCC70428.1 - 2.2e-07 30.2 0.9 0.15 11.1 0.0 3.6 2 1 1 3 3 3 2 KaiC AAA_24 PF13479.1 CCC70428.1 - 1e-06 28.5 0.0 0.071 12.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain Sigma54_activat PF00158.21 CCC70428.1 - 3.9e-06 26.4 0.1 0.082 12.3 0.0 3.7 3 1 0 3 3 2 2 Sigma-54 interaction domain ResIII PF04851.10 CCC70428.1 - 4.5e-06 26.6 0.0 0.0054 16.5 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_18 PF13238.1 CCC70428.1 - 6.6e-06 26.4 0.0 0.13 12.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 CCC70428.1 - 6.8e-06 26.1 0.0 0.16 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 CCC70428.1 - 1.2e-05 24.6 0.5 0.074 12.2 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_11 PF13086.1 CCC70428.1 - 1.2e-05 25.0 0.0 0.031 13.8 0.0 2.5 2 1 0 2 2 2 2 AAA domain DUF815 PF05673.8 CCC70428.1 - 1.6e-05 24.0 0.0 0.045 12.6 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 CCC70428.1 - 1.7e-05 23.8 0.1 0.087 11.6 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 CCC70428.1 - 1.7e-05 24.8 0.0 0.1 12.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 CCC70428.1 - 1.8e-05 25.0 0.0 0.055 13.7 0.0 3.6 3 1 0 3 3 2 1 ABC transporter Arch_ATPase PF01637.13 CCC70428.1 - 4.2e-05 23.3 0.1 0.21 11.2 0.0 3.6 2 2 2 4 4 4 2 Archaeal ATPase NACHT PF05729.7 CCC70428.1 - 5.1e-05 22.9 0.1 1.1 8.8 0.0 3.6 4 0 0 4 4 3 1 NACHT domain Bac_DnaA PF00308.13 CCC70428.1 - 5.5e-05 22.9 0.0 0.071 12.7 0.0 2.4 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_3 PF07726.6 CCC70428.1 - 5.8e-05 22.7 0.0 0.45 10.1 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 CCC70428.1 - 0.00025 20.1 0.0 0.46 9.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 CCC70428.1 - 0.00042 19.9 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 CCC70428.1 - 0.003 16.4 0.1 1.2 7.8 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain NTPase_1 PF03266.10 CCC70428.1 - 0.006 16.3 1.5 2.3 7.8 0.0 3.9 4 1 1 5 5 3 1 NTPase IPT PF01745.11 CCC70428.1 - 0.0072 15.5 0.1 1.3 8.1 0.0 2.3 2 0 0 2 2 2 1 Isopentenyl transferase KAP_NTPase PF07693.9 CCC70428.1 - 0.0083 15.1 0.3 1.2 8.0 0.0 3.0 2 2 2 4 4 4 1 KAP family P-loop domain Zot PF05707.7 CCC70428.1 - 0.0084 15.6 0.3 3.7 6.9 0.1 3.5 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) UPF0079 PF02367.12 CCC70428.1 - 0.03 13.9 0.1 4.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 CCC70428.1 - 0.03 14.1 0.6 3.2 7.6 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase AAA_10 PF12846.2 CCC70428.1 - 0.035 13.5 1.7 22 4.3 0.0 3.9 3 1 0 3 3 3 0 AAA-like domain DEAD PF00270.24 CCC70428.1 - 0.039 13.4 0.2 16 4.9 0.0 3.5 3 1 1 4 4 4 0 DEAD/DEAH box helicase T2SE PF00437.15 CCC70428.1 - 0.045 12.6 0.0 2.1 7.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein KTI12 PF08433.5 CCC70428.1 - 0.066 12.4 0.2 8.4 5.5 0.0 2.7 2 1 0 2 2 2 0 Chromatin associated protein KTI12 Viral_helicase1 PF01443.13 CCC70428.1 - 0.22 10.9 0.0 10 5.5 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Cyclin_N PF00134.18 CCC70429.1 - 1e-15 57.4 0.2 1.6e-15 56.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 CCC70429.1 - 1e-09 39.0 0.2 1e-09 39.0 0.1 1.7 2 1 0 2 2 2 1 Cyclin PGC7_Stella PF15549.1 CCC70429.1 - 0.031 14.2 1.0 0.14 12.1 0.0 2.1 1 1 1 2 2 2 0 PGC7/Stella/Dppa3 domain Mlf1IP PF10248.4 CCC70429.1 - 0.14 11.8 1.9 0.2 11.2 1.3 1.4 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Na_Ca_ex PF01699.19 CCC70430.1 - 1.6e-49 167.1 38.5 8e-26 90.3 6.3 2.6 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Ribosomal_60s PF00428.14 CCC70432.1 - 1.5e-23 83.0 12.3 1.7e-23 82.7 8.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Sigma70_ner PF04546.8 CCC70432.1 - 0.035 13.7 1.2 0.044 13.4 0.8 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Treacle PF03546.9 CCC70432.1 - 0.48 9.1 6.9 0.62 8.7 4.8 1.1 1 0 0 1 1 1 0 Treacher Collins syndrome protein Treacle IATP PF04568.7 CCC70433.1 - 9.1e-17 60.9 0.1 9.8e-17 60.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP HMGL-like PF00682.14 CCC70434.1 - 3.3e-74 249.5 0.2 5.5e-74 248.8 0.1 1.4 1 0 0 1 1 1 1 HMGL-like Trp_syntA PF00290.15 CCC70434.1 - 0.066 11.7 0.0 7.6 4.9 0.0 2.4 2 0 0 2 2 2 0 Tryptophan synthase alpha chain Mit_KHE1 PF10173.4 CCC70435.1 - 2.3e-57 193.8 2.1 2.9e-57 193.5 1.5 1.1 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Ribosomal_L41 PF05162.8 CCC70436.1 - 3.4e-09 36.1 25.8 3.6e-09 36.1 17.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L41 DUF1601 PF07671.6 CCC70436.1 - 0.25 10.9 1.7 0.28 10.8 1.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1601) Metallophos PF00149.23 CCC70438.1 - 3.8e-41 140.6 0.4 5e-41 140.3 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase R3H PF01424.17 CCC70439.1 - 1.2e-09 37.7 0.0 2.7e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 R3H domain SUZ PF12752.2 CCC70439.1 - 0.27 11.7 3.4 0.76 10.3 2.3 1.8 1 1 0 1 1 1 0 SUZ domain Ufd2P_core PF10408.4 CCC70440.1 - 1.1e-178 595.4 16.9 1.5e-178 594.9 11.7 1.2 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 CCC70440.1 - 6.9e-29 99.6 1.0 2.1e-28 98.0 0.7 1.9 1 0 0 1 1 1 1 U-box domain Ribosomal_L29 PF00831.18 CCC70441.1 - 4e-17 61.6 3.3 4e-17 61.6 2.3 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein Hydantoinase_A PF01968.13 CCC70441.1 - 0.15 11.1 1.3 0.15 11.0 0.9 1.1 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase MRP-L47 PF06984.8 CCC70441.1 - 0.25 11.2 3.5 0.24 11.3 0.5 2.3 1 1 1 2 2 2 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) DUF4404 PF14357.1 CCC70441.1 - 0.34 11.3 3.3 1.1 9.7 1.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) EcoEI_R_C PF08463.5 CCC70441.1 - 1.4 8.7 10.1 9.7 6.0 7.0 1.8 1 1 0 1 1 1 0 EcoEI R protein C-terminal DUF4600 PF15372.1 CCC70441.1 - 2.4 8.3 11.2 13 5.9 7.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4600) Arf PF00025.16 CCC70442.1 - 3.1e-78 260.9 0.0 3.6e-78 260.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 CCC70442.1 - 2.6e-14 52.9 0.0 2.8e-14 52.8 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 CCC70442.1 - 6.2e-14 51.6 0.0 7.5e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 CCC70442.1 - 4.4e-11 42.0 0.5 4.8e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 CCC70442.1 - 8.8e-11 41.3 0.0 1.1e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 CCC70442.1 - 1.5e-10 41.6 0.0 2e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 CCC70442.1 - 8.4e-06 25.7 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 CCC70442.1 - 0.0057 16.1 0.0 0.027 13.8 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRP54 PF00448.17 CCC70442.1 - 0.006 16.0 0.2 0.011 15.1 0.1 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_33 PF13671.1 CCC70442.1 - 0.0069 16.2 0.1 0.011 15.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 CCC70442.1 - 0.021 14.5 0.5 2.5 7.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 CCC70442.1 - 0.032 14.5 0.1 0.059 13.6 0.1 1.5 1 1 0 1 1 1 0 ABC transporter 6PF2K PF01591.13 CCC70442.1 - 0.042 12.9 0.1 0.061 12.3 0.1 1.4 1 1 0 1 1 1 0 6-phosphofructo-2-kinase DBD_Tnp_Mut PF03108.10 CCC70442.1 - 0.072 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 MuDR family transposase cobW PF02492.14 CCC70442.1 - 0.075 12.4 0.1 6.3 6.2 0.1 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Prenyltransf PF01255.14 CCC70443.1 - 2.1e-05 23.7 0.0 3.7e-05 22.9 0.0 1.4 1 1 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Cas_TM1802 PF09484.5 CCC70443.1 - 0.017 13.6 1.0 0.028 12.9 0.7 1.2 1 0 0 1 1 1 0 CRISPR-associated protein TM1802 (cas_TM1802) Sugar_tr PF00083.19 CCC70444.1 - 3e-127 424.9 30.8 3.6e-127 424.6 21.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC70444.1 - 2.5e-20 72.4 34.2 8.1e-15 54.3 8.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily WD40 PF00400.27 CCC70445.1 - 2.5e-17 62.0 11.7 6.2e-05 22.7 0.0 8.2 8 0 0 8 8 8 3 WD domain, G-beta repeat Sec31 PF11549.3 CCC70445.1 - 3.4e-16 58.5 0.4 1.5e-15 56.5 0.3 2.2 1 0 0 1 1 1 1 Protein transport protein SEC31 SRA1 PF07304.6 CCC70445.1 - 1.5e-08 34.5 0.0 1.5e-08 34.5 0.0 3.2 4 0 0 4 4 4 1 Steroid receptor RNA activator (SRA1) P16-Arc PF04699.9 CCC70445.1 - 6.8e-05 22.9 1.8 0.00024 21.1 1.3 1.9 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) eIF2A PF08662.6 CCC70445.1 - 0.00032 20.4 3.5 0.028 14.1 0.1 3.4 1 1 3 4 4 4 1 Eukaryotic translation initiation factor eIF2A Sec16_C PF12931.2 CCC70445.1 - 0.00088 19.0 1.8 0.0019 18.0 1.2 1.5 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 CCC70445.1 - 0.0096 15.7 0.9 0.05 13.4 0.7 2.1 1 1 1 2 2 2 1 Prp18 domain CHCH PF06747.8 CCC70446.1 - 0.00039 20.2 6.6 0.00039 20.2 4.6 2.3 2 1 0 2 2 2 1 CHCH domain MttA_Hcf106 PF02416.11 CCC70446.1 - 0.099 11.7 1.7 0.12 11.5 0.6 1.5 1 1 0 1 1 1 0 mttA/Hcf106 family IncA PF04156.9 CCC70446.1 - 0.18 11.3 3.1 0.24 10.9 2.2 1.1 1 0 0 1 1 1 0 IncA protein Lin-8 PF03353.10 CCC70446.1 - 0.31 10.2 5.3 0.34 10.1 3.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3128 PF11326.3 CCC70446.1 - 8.2 6.6 8.0 5.2 7.2 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) Pro_isomerase PF00160.16 CCC70447.1 - 4.6e-44 150.3 0.4 8.2e-44 149.5 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 CCC70447.1 - 3e-05 23.5 2.5 0.16 11.6 0.2 2.5 2 1 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 CCC70447.1 - 6.4e-05 22.5 2.1 0.056 13.3 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 CCC70447.1 - 0.00082 18.8 8.8 0.0053 16.3 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Gas_vesicle_C PF01304.12 CCC70447.1 - 0.31 10.6 2.9 0.33 10.6 0.5 2.1 2 0 0 2 2 2 0 Gas vesicles protein GVPc repeated domain TPR_6 PF13174.1 CCC70447.1 - 0.4 11.2 2.8 4.7 7.8 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat CDP-OH_P_transf PF01066.16 CCC70448.1 - 7.7e-17 61.4 3.3 1.5e-16 60.5 2.3 1.6 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase SDA1 PF05285.7 CCC70449.1 - 2e-99 332.9 29.4 2e-99 332.9 20.4 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 CCC70449.1 - 7.4e-23 80.5 0.1 1.9e-22 79.3 0.1 1.8 1 0 0 1 1 1 1 NUC130/3NT domain ATP-grasp_2 PF08442.5 CCC70450.1 - 3.4e-72 242.0 1.8 5.3e-72 241.4 1.3 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 CCC70450.1 - 1.3e-25 89.7 0.2 2.5e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 CCC70450.1 - 1.2e-05 24.6 0.3 2.4e-05 23.6 0.2 1.6 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 CCC70450.1 - 0.0053 16.3 0.4 0.015 14.8 0.3 1.8 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 CCC70450.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp domain MPC PF03650.8 CCC70451.1 - 8.1e-49 164.5 0.1 9.6e-49 164.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ANTH PF07651.11 CCC70452.1 - 8.9e-55 185.3 0.6 8.9e-55 185.3 0.5 2.6 1 1 2 3 3 3 1 ANTH domain ENTH PF01417.15 CCC70452.1 - 1.4e-06 28.1 2.4 3.6e-06 26.8 0.1 2.7 2 1 1 3 3 3 1 ENTH domain DUF342 PF03961.8 CCC70452.1 - 0.04 12.3 5.5 0.063 11.6 3.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Muted PF14942.1 CCC70452.1 - 1.1 9.1 10.9 0.98 9.2 4.7 2.2 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein APG6 PF04111.7 CCC70452.1 - 1.9 7.4 14.4 0.07 12.1 5.5 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF2215 PF10225.4 CCC70452.1 - 2.8 7.3 7.1 8.8 5.6 0.3 2.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2215) D123 PF07065.9 CCC70453.1 - 3.5e-113 377.6 3.9 4.4e-113 377.3 2.7 1.1 1 0 0 1 1 1 1 D123 BP28CT PF08146.7 CCC70453.1 - 0.074 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 BP28CT (NUC211) domain TFIIB PF00382.14 CCC70454.1 - 8e-55 182.5 0.8 6.3e-27 93.1 0.1 2.6 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 CCC70454.1 - 3.8e-27 94.3 0.9 3.8e-27 94.3 0.6 2.4 3 0 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.7 CCC70454.1 - 2.4e-10 39.5 2.4 4.7e-10 38.6 1.7 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_N PF00134.18 CCC70454.1 - 1.4e-05 24.6 0.2 0.017 14.7 0.1 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Multi-haem_cyto PF13447.1 CCC70454.1 - 0.02 13.9 0.2 0.086 11.8 0.0 2.0 2 0 0 2 2 2 0 Seven times multi-haem cytochrome CxxCH CPDase PF07823.6 CCC70455.1 - 1.7e-63 213.6 0.0 2e-63 213.4 0.0 1.0 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 CCC70455.1 - 0.00015 21.5 0.0 0.00074 19.2 0.0 1.9 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily DUF3723 PF12520.3 CCC70455.1 - 0.057 11.9 0.1 0.49 8.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3723) Glucosamine_iso PF01182.15 CCC70456.1 - 1.3e-11 44.6 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HSF_DNA-bind PF00447.12 CCC70457.1 - 2.4e-29 101.5 3.9 5.1e-29 100.4 2.7 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding RRM_1 PF00076.17 CCC70458.1 - 1.2e-31 108.0 3.1 1.3e-11 43.9 0.1 6.2 6 1 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC70458.1 - 6e-22 77.4 0.1 2.2e-07 30.7 0.0 4.8 4 1 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC70458.1 - 3.6e-18 65.1 0.4 0.00011 22.0 0.0 4.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trypan_PARP PF05887.6 CCC70458.1 - 0.3 10.9 7.9 0.73 9.6 5.5 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Oxidored_FMN PF00724.15 CCC70459.1 - 2.2e-123 411.6 0.0 2.5e-123 411.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Bromodomain PF00439.20 CCC70460.1 - 1.7e-27 95.1 1.4 3.8e-27 94.0 1.0 1.6 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 CCC70460.1 - 5.2e-09 36.1 0.2 1.1e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 CCC70460.1 - 1.4e-08 34.6 0.0 2.4e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCC70460.1 - 0.00061 19.8 0.0 0.0012 18.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 CCC70460.1 - 0.0024 17.8 0.1 0.0053 16.7 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCC70460.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein DUF2702 PF10863.3 CCC70461.1 - 8.5e-54 181.1 12.3 8.5e-54 181.1 8.6 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2702) TT_ORF2 PF02957.10 CCC70461.1 - 0.27 11.9 6.0 5.4 7.7 0.2 2.2 2 0 0 2 2 2 0 TT viral ORF2 DUF3245 PF11595.3 CCC70461.1 - 0.35 11.1 24.0 2.7 8.2 4.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3245) DEAD PF00270.24 CCC70462.1 - 1.1e-40 138.8 0.2 1e-39 135.7 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC70462.1 - 3.7e-27 94.0 0.1 8e-27 92.9 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC70462.1 - 0.0021 17.8 0.5 0.0062 16.3 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Dynactin_p22 PF07426.6 CCC70462.1 - 0.022 14.0 1.7 0.13 11.5 0.0 2.3 2 0 0 2 2 2 0 Dynactin subunit p22 DUF1285 PF06938.6 CCC70462.1 - 0.11 12.4 0.3 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1285) DUF3231 PF11553.3 CCC70463.1 - 0.018 14.5 0.6 0.067 12.6 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3231) DUF2393 PF09624.5 CCC70463.1 - 0.099 12.1 1.0 0.18 11.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) XPG_N PF00752.12 CCC70465.1 - 5.9e-35 119.5 0.0 1.4e-34 118.3 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCC70465.1 - 1.7e-26 92.0 0.8 7.2e-26 90.0 0.0 2.6 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 CCC70465.1 - 0.0035 17.5 1.8 0.01 16.0 0.0 2.7 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold UPF0122 PF04297.9 CCC70466.1 - 0.27 11.2 5.4 0.78 9.7 3.7 1.8 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like HDAC4_Gln PF12203.3 CCC70466.1 - 1.5 8.8 8.9 0.18 11.7 2.9 1.9 2 0 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 MFS_1 PF07690.11 CCC70468.1 - 8.6e-31 106.9 26.8 8.6e-31 106.9 18.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Adaptin_N PF01602.15 CCC70469.1 - 4.2e-101 338.8 5.3 5.2e-101 338.5 3.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 CCC70469.1 - 8.7e-11 41.9 0.3 7e-06 26.2 0.0 4.7 4 2 0 4 4 4 2 HEAT repeats HEAT PF02985.17 CCC70469.1 - 3.6e-07 29.7 0.2 1.8 8.8 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat Cnd1 PF12717.2 CCC70469.1 - 0.00047 20.0 5.3 0.0046 16.8 0.0 3.9 3 1 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Cwf_Cwc_15 PF04889.7 CCC70469.1 - 1.6 8.3 14.4 2.6 7.6 10.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop14 PF04147.7 CCC70469.1 - 1.7 6.4 24.6 5.7 4.7 14.4 2.3 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.9 CCC70469.1 - 3.5 5.5 15.0 5.5 4.8 10.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Kdo PF06293.9 CCC70470.1 - 4.1e-09 35.7 0.0 8.6e-09 34.7 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCC70470.1 - 3e-05 23.4 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 CCC70470.1 - 5.6e-05 22.4 0.0 7.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 CCC70470.1 - 0.00075 19.2 0.0 0.0032 17.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 CCC70470.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.4 1 1 0 1 1 1 0 Ecdysteroid kinase Pkinase_Tyr PF07714.12 CCC70470.1 - 0.11 11.4 0.0 0.16 10.9 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CCC70470.1 - 0.12 11.6 0.1 0.28 10.4 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL DUF2424 PF10340.4 CCC70471.1 - 2.1e-90 303.0 2.1 1.6e-89 300.1 1.5 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 CCC70471.1 - 3e-18 66.1 0.0 1.6e-17 63.7 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 CCC70471.1 - 0.00064 18.5 0.0 0.49 9.0 0.0 2.3 2 0 0 2 2 2 2 Carboxylesterase family Chlorophyllase2 PF12740.2 CCC70471.1 - 0.13 11.1 0.1 3.6 6.4 0.0 2.1 1 1 1 2 2 2 0 Chlorophyllase enzyme PhoD PF09423.5 CCC70472.1 - 1.6e-06 27.0 0.0 2.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase GTP_cyclohydroI PF01227.17 CCC70473.1 - 5e-78 260.4 0.5 6e-78 260.2 0.4 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 CCC70473.1 - 8.9e-06 25.5 0.0 2.7e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 QueF-like protein DnaJ_CXXCXGXG PF00684.14 CCC70474.1 - 2.3e-05 24.3 7.0 0.021 14.8 0.5 2.5 2 1 0 2 2 2 2 DnaJ central domain DUF2082 PF09855.4 CCC70474.1 - 0.057 13.2 0.7 0.12 12.2 0.5 1.5 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF3821 PF12863.2 CCC70474.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) HypA PF01155.14 CCC70474.1 - 0.12 12.0 1.4 1.6 8.4 0.2 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF2318 PF10080.4 CCC70474.1 - 0.89 9.3 3.5 0.74 9.6 0.8 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) AAA PF00004.24 CCC70475.1 - 1e-51 174.5 0.0 1.2e-42 145.2 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 CCC70475.1 - 2.3e-07 30.9 0.7 3.3e-05 23.9 0.0 3.1 2 2 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 CCC70475.1 - 5.9e-07 29.5 0.0 2.2e-05 24.4 0.0 3.1 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) Sigma54_activ_2 PF14532.1 CCC70475.1 - 1.9e-06 27.9 0.2 0.093 12.7 0.0 3.1 3 0 0 3 3 3 2 Sigma-54 interaction domain IstB_IS21 PF01695.12 CCC70475.1 - 1.9e-05 24.1 0.0 0.00034 20.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.1 CCC70475.1 - 3.6e-05 23.9 0.1 0.00039 20.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCC70475.1 - 0.00011 21.9 0.0 0.00043 20.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCC70475.1 - 0.0002 21.0 0.0 0.026 14.2 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 CCC70475.1 - 0.00025 20.9 0.0 0.012 15.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCC70475.1 - 0.00028 21.7 5.3 0.012 16.3 0.0 4.7 4 0 0 4 4 4 1 AAA domain Bromodomain PF00439.20 CCC70475.1 - 0.00068 19.5 0.0 0.0029 17.4 0.0 2.1 1 0 0 1 1 1 1 Bromodomain TIP49 PF06068.8 CCC70475.1 - 0.0017 17.1 0.4 0.02 13.6 0.0 2.4 3 0 0 3 3 3 1 TIP49 C-terminus Sigma54_activat PF00158.21 CCC70475.1 - 0.0034 16.8 0.0 0.9 8.9 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 CCC70475.1 - 0.0046 16.3 0.1 0.031 13.6 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCC70475.1 - 0.0084 15.9 0.9 0.019 14.8 0.0 2.1 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 CCC70475.1 - 0.01 15.9 0.0 0.07 13.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ResIII PF04851.10 CCC70475.1 - 0.016 15.0 0.0 0.016 15.0 0.0 3.2 4 0 0 4 4 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 CCC70475.1 - 0.02 15.1 3.7 0.1 12.8 0.0 3.5 3 0 0 3 3 3 0 ABC transporter AAA_3 PF07726.6 CCC70475.1 - 0.023 14.3 0.0 0.055 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CCC70475.1 - 0.032 13.4 0.0 0.11 11.6 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 CCC70475.1 - 0.037 13.0 0.0 0.12 11.3 0.0 1.7 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 CCC70475.1 - 0.13 12.5 0.0 0.13 12.5 0.0 3.4 2 1 0 2 2 1 0 AAA domain Sec63 PF02889.11 CCC70476.1 - 3.7e-136 453.4 0.0 2.6e-92 309.4 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 CCC70476.1 - 1.8e-53 180.4 2.2 3.2e-28 98.3 0.4 4.2 5 0 0 5 5 5 2 DEAD/DEAH box helicase ResIII PF04851.10 CCC70476.1 - 3.9e-20 72.4 0.7 5.5e-09 36.1 0.0 3.1 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 CCC70476.1 - 2.2e-18 65.8 0.0 7.4e-08 32.1 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCC70476.1 - 1.4e-06 27.3 0.2 0.0028 16.4 0.1 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain PhoH PF02562.11 CCC70476.1 - 5.9e-05 22.4 0.0 0.022 13.9 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.1 CCC70476.1 - 8e-05 22.3 0.0 0.013 15.2 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 CCC70476.1 - 0.00018 21.6 6.5 0.077 13.1 0.1 4.3 4 2 0 4 4 4 2 AAA domain AAA PF00004.24 CCC70476.1 - 0.00028 21.0 6.3 0.46 10.6 0.0 4.3 4 1 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 CCC70476.1 - 0.00064 19.1 0.6 2 7.8 0.0 3.9 5 0 0 5 5 5 2 IstB-like ATP binding protein AAA_30 PF13604.1 CCC70476.1 - 0.0098 15.4 0.0 5.7 6.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain T2SE PF00437.15 CCC70476.1 - 0.026 13.4 0.0 3.5 6.4 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 CCC70476.1 - 0.044 13.2 3.3 21 4.4 0.0 4.4 4 1 1 5 5 5 0 AAA-like domain DUF2361 PF10153.4 CCC70477.1 - 9.4e-37 125.6 14.5 9.4e-37 125.6 10.0 2.0 2 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2361) PWWP PF00855.12 CCC70477.1 - 1.1 9.4 3.5 7.7 6.7 2.5 2.4 1 1 0 1 1 1 0 PWWP domain DDE_1 PF03184.14 CCC70479.1 - 0.00015 20.9 0.1 0.0008 18.6 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease Bd3614_N PF14442.1 CCC70479.1 - 0.78 9.7 4.2 1.8 8.5 2.9 1.5 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal Rtt102p PF09510.5 CCC70480.1 - 1.1e-13 51.3 0.3 1.1e-13 51.3 0.2 2.1 3 0 0 3 3 3 1 Rtt102p-like transcription regulator protein IER PF05760.7 CCC70480.1 - 0.045 13.6 1.2 0.053 13.4 0.8 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) RNase_T PF00929.19 CCC70481.1 - 2.4e-27 96.2 0.1 4.9e-27 95.2 0.1 1.5 1 0 0 1 1 1 1 Exonuclease CTP_transf_2 PF01467.21 CCC70482.1 - 1.5e-14 54.3 0.0 2.8e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase MA3 PF02847.12 CCC70483.1 - 1.6e-18 66.4 2.2 3.1e-18 65.5 0.0 2.7 3 1 0 3 3 3 1 MA3 domain MIF4G PF02854.14 CCC70483.1 - 3e-11 43.1 13.6 8.6e-11 41.6 9.4 1.9 1 0 0 1 1 1 1 MIF4G domain IlvGEDA_leader PF08046.6 CCC70483.1 - 0.016 14.3 0.0 0.035 13.2 0.0 1.6 1 0 0 1 1 1 0 IlvGEDA operon leader peptide Glyco_hydro_17 PF00332.13 CCC70484.1 - 2.6e-10 39.8 1.3 2.6e-10 39.8 0.9 1.8 2 1 0 2 2 2 1 Glycosyl hydrolases family 17 SR-25 PF10500.4 CCC70484.1 - 0.081 12.3 3.7 0.14 11.6 2.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Sclerostin PF05463.6 CCC70484.1 - 0.1 12.0 0.1 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Sclerostin (SOST) PAP1 PF08601.5 CCC70484.1 - 0.23 11.0 4.2 0.34 10.5 2.9 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 MSP1_C PF07462.6 CCC70484.1 - 1.8 6.8 8.8 2.4 6.4 6.1 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus RAP1 PF07218.6 CCC70484.1 - 1.8 6.5 10.2 2.4 6.1 7.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Ribosomal_60s PF00428.14 CCC70484.1 - 7 7.1 18.4 2.9 8.3 10.5 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein G-patch PF01585.18 CCC70485.1 - 1.9e-11 43.5 0.1 4.1e-11 42.4 0.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CCC70485.1 - 4.5e-05 23.2 0.1 4.5e-05 23.2 0.1 3.8 2 1 0 2 2 1 1 DExH-box splicing factor binding site DUF936 PF06075.7 CCC70485.1 - 0.02 13.8 20.7 0.026 13.4 14.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) MIP-T3 PF10243.4 CCC70485.1 - 0.02 13.3 39.5 0.028 12.9 27.4 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF2201_N PF13203.1 CCC70485.1 - 0.032 13.4 14.1 0.043 13.0 9.8 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1510 PF07423.6 CCC70485.1 - 0.043 13.1 28.4 0.083 12.2 19.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) RR_TM4-6 PF06459.7 CCC70485.1 - 0.11 12.3 23.5 0.17 11.7 16.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 CCC70485.1 - 0.13 10.2 26.3 0.17 9.9 18.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 CCC70485.1 - 0.92 7.1 18.2 1.1 6.9 12.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NAM-associated PF14303.1 CCC70485.1 - 1.3 9.3 39.8 0.47 10.7 24.9 1.9 2 0 0 2 2 2 0 No apical meristem-associated C-terminal domain SOBP PF15279.1 CCC70485.1 - 1.3 9.2 16.8 2 8.7 11.6 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein AAA_11 PF13086.1 CCC70485.1 - 1.7 8.1 12.0 2.5 7.6 8.3 1.4 1 0 0 1 1 1 0 AAA domain YL1 PF05764.8 CCC70485.1 - 2.6 7.5 45.7 4 6.9 31.4 1.4 1 1 0 1 1 1 0 YL1 nuclear protein ABC_membrane PF00664.18 CCC70486.1 - 1.3e-68 231.4 45.9 6.2e-39 134.0 8.1 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCC70486.1 - 1.2e-44 151.9 11.0 9.7e-29 100.4 0.1 5.0 5 1 0 5 5 4 2 ABC transporter AAA_23 PF13476.1 CCC70486.1 - 1.1e-08 35.7 4.2 3.6e-07 30.7 1.6 3.9 3 1 1 4 4 2 2 AAA domain SMC_N PF02463.14 CCC70486.1 - 1e-07 31.4 4.5 0.0071 15.5 0.1 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 CCC70486.1 - 1.8e-07 30.5 0.3 0.03 13.8 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 CCC70486.1 - 2.9e-06 27.4 17.2 0.00011 22.2 0.0 5.7 3 2 2 5 5 5 1 AAA domain DUF258 PF03193.11 CCC70486.1 - 1.6e-05 24.1 0.1 0.031 13.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 CCC70486.1 - 7.1e-05 21.8 0.0 0.035 13.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 CCC70486.1 - 8.2e-05 23.4 5.8 0.087 13.6 0.2 3.4 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.1 CCC70486.1 - 0.00018 21.6 2.9 1.6 8.8 0.6 3.6 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CCC70486.1 - 0.00026 20.1 0.1 0.044 12.8 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin Miro PF08477.8 CCC70486.1 - 0.00033 21.1 0.7 0.76 10.2 0.0 3.6 3 0 0 3 3 3 1 Miro-like protein MMR_HSR1 PF01926.18 CCC70486.1 - 0.0016 18.4 3.4 0.12 12.2 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_30 PF13604.1 CCC70486.1 - 0.0038 16.8 2.1 1.8 8.0 0.0 3.3 4 0 0 4 4 3 1 AAA domain IstB_IS21 PF01695.12 CCC70486.1 - 0.004 16.6 0.1 1 8.7 0.0 3.3 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_16 PF13191.1 CCC70486.1 - 0.0048 16.9 0.8 0.28 11.1 0.0 3.2 2 1 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 CCC70486.1 - 0.0072 16.0 0.4 0.7 9.6 0.0 3.8 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA PF00004.24 CCC70486.1 - 0.011 15.8 0.2 0.27 11.4 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 CCC70486.1 - 0.021 14.2 0.0 7.7 5.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 CCC70486.1 - 0.022 14.6 0.1 2.1 8.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CCC70486.1 - 0.026 13.9 0.5 0.18 11.2 0.0 2.5 3 0 0 3 3 2 0 FtsK/SpoIIIE family Vps51 PF08700.6 CCC70486.1 - 0.039 13.7 0.1 0.039 13.7 0.1 3.3 3 1 0 3 3 2 0 Vps51/Vps67 ATP-synt_ab PF00006.20 CCC70486.1 - 0.04 13.4 0.1 6.8 6.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.14 CCC70486.1 - 0.053 12.9 0.4 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.17 CCC70486.1 - 0.061 13.5 0.3 18 5.5 0.0 3.4 3 0 0 3 3 3 0 RNA helicase PduV-EutP PF10662.4 CCC70486.1 - 0.07 12.6 1.0 3.1 7.3 0.0 3.3 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation UPF0079 PF02367.12 CCC70486.1 - 0.087 12.4 0.4 0.86 9.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 CCC70486.1 - 0.089 12.7 0.2 3.9 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 CCC70486.1 - 0.1 12.4 0.1 0.1 12.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 AAA_18 PF13238.1 CCC70486.1 - 0.26 11.6 0.0 0.26 11.6 0.0 4.8 6 0 0 6 6 4 0 AAA domain Dynamin_N PF00350.18 CCC70486.1 - 0.27 11.0 8.2 4.1 7.1 0.1 3.9 4 0 0 4 4 4 0 Dynamin family TrwB_AAD_bind PF10412.4 CCC70486.1 - 4.5 5.7 8.3 0.83 8.2 0.1 2.6 3 0 0 3 3 2 0 Type IV secretion-system coupling protein DNA-binding domain Glyco_hydro_17 PF00332.13 CCC70487.1 - 9.8e-74 248.1 2.4 1.1e-73 247.9 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF1088 PF06469.6 CCC70487.1 - 0.05 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1088) SURF4 PF02077.10 CCC70488.1 - 7.7e-97 323.8 9.1 8.9e-97 323.6 6.3 1.0 1 0 0 1 1 1 1 SURF4 family DnaJ PF00226.26 CCC70489.1 - 4.2e-17 61.6 0.1 4.2e-17 61.6 0.1 2.6 3 0 0 3 3 3 1 DnaJ domain GCD14 PF08704.5 CCC70489.1 - 0.71 9.3 0.0 0.71 9.3 0.0 2.7 2 1 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit DEPP PF15343.1 CCC70489.1 - 0.78 9.3 6.4 1.7 8.1 4.5 1.6 1 0 0 1 1 1 0 Decidual protein induced by progesterone family StbA PF06406.6 CCC70490.1 - 0.25 10.2 1.6 15 4.4 0.0 2.3 2 0 0 2 2 2 0 StbA protein Ferrochelatase PF00762.14 CCC70492.1 - 9.1e-87 290.9 0.0 1e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase Dimer_Tnp_hAT PF05699.9 CCC70493.1 - 5.3e-09 35.5 0.2 1.6e-08 34.0 0.1 1.8 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region PI31_Prot_N PF11566.3 CCC70494.1 - 0.14 11.7 3.0 0.5 9.9 0.1 2.4 2 0 0 2 2 2 0 PI31 proteasome regulator N-terminal Flo11 PF10182.4 CCC70495.1 - 4e-50 169.3 5.4 4e-50 169.3 3.7 2.3 3 0 0 3 3 3 1 Flo11 domain WIF PF02019.13 CCC70495.1 - 0.11 11.9 1.9 1.4 8.4 0.0 2.9 3 0 0 3 3 3 0 WIF domain Sugar_tr PF00083.19 CCC70496.1 - 3.8e-166 553.1 31.8 4.3e-166 552.9 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC70496.1 - 1.6e-27 96.1 19.2 1.6e-27 96.1 13.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCC70496.1 - 0.0038 15.4 3.6 0.0053 14.9 0.6 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector G6PD_C PF02781.11 CCC70497.1 - 7.9e-104 346.6 0.0 1e-103 346.2 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CCC70497.1 - 4.7e-55 186.6 0.0 6.9e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Sir1 PF11603.3 CCC70498.1 - 6.2e-15 55.4 6.8 7.6e-08 32.5 0.4 3.8 3 1 0 3 3 3 3 Regulatory protein Sir1 RUN PF02759.14 CCC70498.1 - 0.046 13.4 0.3 5.7 6.7 0.0 2.6 2 0 0 2 2 2 0 RUN domain NDUF_C2 PF06374.6 CCC70498.1 - 0.054 13.4 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) CRAL_TRIO_2 PF13716.1 CCC70499.1 - 1.6e-31 109.2 1.6 2.9e-31 108.4 0.3 2.0 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 CCC70499.1 - 2.1e-08 33.9 0.8 5.1e-08 32.6 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain TFIID-18kDa PF02269.11 CCC70499.1 - 0.045 13.5 0.5 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Aconitase PF00330.15 CCC70500.1 - 4.5e-173 576.0 0.0 9.2e-173 574.9 0.0 1.5 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 CCC70500.1 - 5.5e-42 142.9 0.0 1.1e-41 142.0 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 CCC70500.1 - 0.072 11.6 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) DNA_pol_phi PF04931.8 CCC70502.1 - 4.3e-150 501.0 33.4 7e-150 500.3 23.1 1.3 1 0 0 1 1 1 1 DNA polymerase phi UME PF08064.8 CCC70502.1 - 0.44 10.5 8.5 0.045 13.6 0.5 3.3 3 0 0 3 3 3 0 UME (NUC010) domain CAF1C_H4-bd PF12265.3 CCC70503.1 - 2.7e-25 88.0 0.1 6.5e-25 86.8 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.27 CCC70503.1 - 7.9e-22 76.2 1.7 5.5e-05 22.8 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat PGM_PMM_I PF02878.11 CCC70504.1 - 4e-15 55.5 0.0 6.2e-08 32.2 0.0 2.6 2 0 0 2 2 2 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.15 CCC70504.1 - 7e-12 45.1 0.1 1.6e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_II PF02879.11 CCC70504.1 - 3.4e-10 40.1 0.0 4.9e-09 36.4 0.0 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II Mitochondr_Som1 PF11093.3 CCC70505.1 - 2e-14 53.1 0.1 2.5e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial export protein Som1 Peptidase_S8 PF00082.17 CCC70506.1 - 3.8e-55 187.0 3.4 7.6e-55 186.0 2.4 1.5 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 CCC70506.1 - 2.8e-13 50.2 0.0 2.8e-13 50.2 0.0 2.0 2 0 0 2 2 2 1 Peptidase inhibitor I9 ABC1 PF03109.11 CCC70506.1 - 0.11 12.4 0.2 0.71 9.8 0.1 2.1 2 0 0 2 2 2 0 ABC1 family DAGK_cat PF00781.19 CCC70507.1 - 3.4e-26 91.2 0.0 7.2e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain tRNA-synt_1c PF00749.16 CCC70508.1 - 3.3e-110 367.6 0.0 7.5e-110 366.4 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA_synt_1c_R1 PF04558.10 CCC70508.1 - 6.1e-56 188.4 1.3 9.9e-56 187.7 0.9 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.13 CCC70508.1 - 2.5e-31 108.6 0.1 2.4e-30 105.4 0.1 2.4 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R2 PF04557.10 CCC70508.1 - 2.8e-24 85.6 5.6 6.7e-24 84.3 3.9 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 Ribosomal_S28e PF01200.13 CCC70510.1 - 1e-33 114.8 3.3 1.1e-33 114.7 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e PIN_4 PF13638.1 CCC70511.1 - 1.8e-31 108.9 0.6 3.1e-31 108.2 0.0 1.7 2 0 0 2 2 2 1 PIN domain RHD3 PF05879.7 CCC70512.1 - 2.1e-247 822.8 27.9 3e-247 822.3 19.4 1.2 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.18 CCC70512.1 - 0.00042 20.2 0.9 0.0015 18.4 0.1 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCC70512.1 - 0.00067 19.5 0.0 0.00067 19.5 0.0 3.5 3 1 0 3 3 3 1 Dynamin family Miro PF08477.8 CCC70512.1 - 0.002 18.5 0.8 0.01 16.3 0.1 2.6 2 0 0 2 2 2 1 Miro-like protein Iron_permease PF04120.7 CCC70512.1 - 0.0034 16.9 0.9 0.0034 16.9 0.6 2.6 3 0 0 3 3 3 1 Low affinity iron permease DUF2254 PF10011.4 CCC70512.1 - 0.029 12.8 0.3 0.12 10.8 0.0 2.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2254) ABC_tran PF00005.22 CCC70512.1 - 0.086 13.1 1.3 0.65 10.2 0.0 2.6 2 0 0 2 2 2 0 ABC transporter DUF234 PF03008.9 CCC70512.1 - 0.18 11.9 6.0 2 8.6 0.2 3.2 3 0 0 3 3 3 0 Archaea bacterial proteins of unknown function ACDC PF14733.1 CCC70512.1 - 0.87 9.7 5.4 8.7 6.5 1.7 3.4 2 1 0 2 2 2 0 AP2-coincident C-terminal DUF410 PF04190.8 CCC70513.1 - 2.6e-75 253.3 2.5 3e-75 253.1 1.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF2802 PF10975.3 CCC70513.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) NUDIX PF00293.23 CCC70514.1 - 3.5e-17 62.3 0.1 4.1e-17 62.0 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain Zn_clus PF00172.13 CCC70515.1 - 1.7e-08 34.2 7.8 3.2e-08 33.3 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DcpS PF05652.7 CCC70516.1 - 1.5e-41 141.2 0.3 3e-41 140.2 0.2 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal DcpS_C PF11969.3 CCC70516.1 - 9.2e-32 109.7 1.1 3.4e-31 107.8 0.1 2.2 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 CCC70516.1 - 0.025 15.1 0.4 0.19 12.3 0.1 2.5 3 0 0 3 3 3 0 HIT domain Med4 PF10018.4 CCC70517.1 - 6.1e-39 133.3 5.2 7.8e-39 133.0 2.3 2.0 2 1 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Rrn6 PF10214.4 CCC70517.1 - 1.2 7.0 6.3 0.19 9.7 1.0 1.8 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor MBOAT PF03062.14 CCC70518.1 - 3.3e-60 203.9 12.9 3.3e-60 203.9 8.9 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Ferrochelatase PF00762.14 CCC70519.1 - 9.1e-87 290.9 0.0 1e-86 290.7 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase CBM_21 PF03370.8 CCC70520.1 - 2e-27 95.3 17.8 2.1e-27 95.3 5.9 3.4 2 0 0 2 2 2 2 Putative phosphatase regulatory subunit Fungal_trans PF04082.13 CCC70521.1 - 8e-18 64.2 2.1 8e-18 64.2 1.5 2.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC70521.1 - 1.4e-05 24.9 10.8 3.8e-05 23.5 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1840 PF08895.6 CCC70521.1 - 2.3 8.2 5.8 0.44 10.5 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) ECH PF00378.15 CCC70522.1 - 4.7e-17 61.9 0.0 7.8e-17 61.2 0.0 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SPA PF08616.5 CCC70522.1 - 0.077 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Stabilization of polarity axis WH1 PF00568.18 CCC70523.1 - 6.3e-36 122.4 0.0 9.9e-36 121.8 0.0 1.3 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 CCC70523.1 - 5.3e-06 25.8 0.8 1.2e-05 24.7 0.6 1.6 1 0 0 1 1 1 1 WH2 motif Ribosomal_S30 PF04758.9 CCC70524.1 - 1.1e-29 101.9 5.0 1.2e-29 101.8 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 ABC2_membrane PF01061.19 CCC70525.1 - 2.7e-83 278.2 52.7 1.1e-42 145.5 16.8 2.5 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 CCC70525.1 - 2.5e-40 136.3 5.4 7e-36 122.0 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 CCC70525.1 - 1.5e-38 132.2 0.0 3.4e-18 66.2 0.0 3.6 4 0 0 4 4 4 2 ABC transporter ABC_trans_N PF14510.1 CCC70525.1 - 4.4e-24 84.3 0.0 9.5e-24 83.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CCC70525.1 - 9e-09 35.0 0.0 3.7e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCC70525.1 - 1.1e-05 25.5 0.1 0.0012 18.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 CCC70525.1 - 4.5e-05 22.6 0.0 0.0032 16.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 CCC70525.1 - 0.00016 21.5 0.0 0.12 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCC70525.1 - 0.00019 21.1 0.2 0.26 10.9 0.0 2.9 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.1 CCC70525.1 - 0.00021 21.5 0.0 0.22 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 CCC70525.1 - 0.00024 20.5 2.2 0.0044 16.5 0.2 3.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_19 PF13245.1 CCC70525.1 - 0.00054 19.6 0.2 1.4 8.6 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain cobW PF02492.14 CCC70525.1 - 0.00075 18.9 2.7 0.19 11.1 0.3 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 CCC70525.1 - 0.00097 18.7 0.3 0.47 10.0 0.1 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 SMC_N PF02463.14 CCC70525.1 - 0.00099 18.4 0.1 0.087 12.0 0.0 2.9 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CCC70525.1 - 0.0016 18.5 0.1 0.46 10.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CCC70525.1 - 0.0023 18.2 0.0 0.078 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 CCC70525.1 - 0.0039 17.1 0.5 0.11 12.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCC70525.1 - 0.0059 17.4 0.0 5.1 7.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 CCC70525.1 - 0.0093 15.9 0.0 0.16 11.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 CCC70525.1 - 0.023 14.3 0.0 2.5 7.7 0.0 2.5 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 CCC70525.1 - 0.055 13.6 0.0 16 5.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 CCC70525.1 - 0.11 11.9 0.8 1.9 7.9 0.2 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 CCC70525.1 - 0.13 11.8 0.3 8.7 5.8 0.2 2.4 2 0 0 2 2 2 0 AAA domain OCD_Mu_crystall PF02423.10 CCC70525.1 - 0.24 10.1 0.0 2.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Ornithine cyclodeaminase/mu-crystallin family Aminotran_5 PF00266.14 CCC70526.1 - 9.6e-34 116.7 0.0 2.4e-33 115.4 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V IF-2B PF01008.12 CCC70527.1 - 1e-85 287.1 0.0 1.9e-85 286.3 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family ABC_sub_bind PF04392.7 CCC70527.1 - 0.032 13.1 0.1 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 ABC transporter substrate binding protein Ras PF00071.17 CCC70528.1 - 3.7e-50 169.4 0.0 4.6e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC70528.1 - 8.5e-17 61.7 0.0 1.8e-16 60.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCC70528.1 - 2.8e-11 42.9 0.0 3.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 CCC70528.1 - 0.00066 19.8 0.2 0.0066 16.6 0.1 2.2 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 CCC70528.1 - 0.0039 16.3 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 CCC70528.1 - 0.025 13.8 0.1 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 CCC70528.1 - 0.025 13.2 2.1 0.63 8.6 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit SRPRB PF09439.5 CCC70528.1 - 0.037 13.2 0.0 0.063 12.4 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 CCC70528.1 - 0.045 13.8 0.1 0.15 12.2 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCC70528.1 - 0.055 13.3 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CCC70528.1 - 0.13 11.9 0.1 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATP_sub_h PF10775.4 CCC70529.1 - 8.7e-15 54.2 0.0 1.3e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h GTP_EFTU PF00009.22 CCC70530.1 - 2.1e-61 206.6 0.3 2.9e-61 206.2 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCC70530.1 - 9.1e-27 93.1 0.1 2.2e-26 91.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCC70530.1 - 1.3e-21 76.4 1.3 3.9e-21 74.9 0.6 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCC70530.1 - 1.5e-05 24.5 0.1 3.9e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCC70530.1 - 2e-05 24.5 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 CCC70530.1 - 0.002 18.6 0.0 0.0035 17.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 CCC70530.1 - 0.023 14.1 0.2 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CbiA PF01656.18 CCC70530.1 - 0.026 13.9 1.0 5 6.4 0.0 2.3 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1708 PF08101.6 CCC70531.1 - 2e-157 524.3 7.7 6.7e-157 522.6 5.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1708) RhoGAP PF00620.22 CCC70531.1 - 0.006 16.1 0.2 0.018 14.6 0.0 1.8 2 0 0 2 2 2 1 RhoGAP domain eIF3g PF12353.3 CCC70532.1 - 0.0013 18.6 1.0 0.0015 18.4 0.7 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G INO80_Ies4 PF08193.6 CCC70532.1 - 0.024 14.5 0.2 0.038 13.9 0.0 1.4 1 1 0 1 1 1 0 INO80 complex subunit Ies4 PFK PF00365.15 CCC70533.1 - 6.5e-168 556.8 4.9 8.3e-126 418.6 1.1 2.1 2 0 0 2 2 2 2 Phosphofructokinase DUF3519 PF12033.3 CCC70535.1 - 0.098 12.8 0.0 0.26 11.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3519) Kelch_5 PF13854.1 CCC70536.1 - 2.2e-32 110.4 1.4 5.6e-05 23.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 CCC70536.1 - 2.5e-32 110.3 1.5 5.1e-07 29.6 0.0 5.8 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 CCC70536.1 - 3.6e-28 97.0 11.2 0.00017 21.3 0.0 6.6 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 CCC70536.1 - 4.9e-24 83.4 1.8 0.00011 22.1 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 CCC70536.1 - 8.8e-19 66.7 2.2 4.9e-06 25.9 0.1 5.9 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 CCC70536.1 - 9.9e-12 44.1 3.7 0.25 11.1 0.0 6.1 6 0 0 6 6 6 4 Kelch motif HALZ PF02183.13 CCC70536.1 - 0.0092 15.6 1.9 0.0092 15.6 1.3 6.1 6 0 0 6 6 6 1 Homeobox associated leucine zipper T2SM PF04612.7 CCC70536.1 - 1.6 8.4 4.4 1.7 8.4 0.1 2.5 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M bZIP_1 PF00170.16 CCC70536.1 - 9.8 6.2 41.6 0.57 10.1 1.0 6.7 7 0 0 7 7 7 0 bZIP transcription factor ApoO PF09769.4 CCC70539.1 - 1.3e-29 102.9 0.2 2.4e-29 102.0 0.0 1.5 2 0 0 2 2 2 1 Apolipoprotein O FAD_binding_6 PF00970.19 CCC70540.1 - 1.2e-10 41.3 0.0 2.1e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 CCC70540.1 - 6.9e-10 39.2 0.0 1.8e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Globin NAD_binding_1 PF00175.16 CCC70540.1 - 7.3e-07 29.7 0.0 1.8e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Protoglobin PF11563.3 CCC70540.1 - 0.00081 19.0 0.3 0.0022 17.6 0.1 1.8 2 1 0 2 2 2 1 Protoglobin NAD_binding_6 PF08030.7 CCC70540.1 - 0.06 13.2 0.1 1.4 8.7 0.1 2.4 1 1 1 2 2 2 0 Ferric reductase NAD binding domain BRCT PF00533.21 CCC70541.1 - 9.6e-20 70.5 1.3 6.5e-05 23.0 0.0 5.6 5 1 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCC70541.1 - 1.1e-07 31.5 0.0 1.5e-06 27.9 0.0 2.9 3 0 0 3 3 3 1 twin BRCT domain Endotoxin_C PF03944.9 CCC70541.1 - 0.22 11.6 0.0 0.22 11.6 0.0 2.7 3 0 0 3 3 3 0 delta endotoxin Ank_2 PF12796.2 CCC70542.1 - 1e-32 112.3 4.2 7.4e-13 48.6 0.0 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 CCC70542.1 - 3e-30 102.5 8.2 4.4e-07 29.3 0.0 6.7 6 0 0 6 6 6 5 Ankyrin repeat SPX PF03105.14 CCC70542.1 - 7.2e-30 104.6 19.2 1.1e-28 100.7 7.6 3.3 2 1 0 2 2 2 1 SPX domain Ank_4 PF13637.1 CCC70542.1 - 2.3e-25 88.4 5.9 1.2e-06 28.8 0.0 5.0 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCC70542.1 - 6.4e-23 78.5 4.2 0.00048 20.1 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 CCC70542.1 - 2.1e-21 75.4 7.9 1.9e-06 27.9 0.0 5.9 2 2 3 5 5 5 5 Ankyrin repeats (many copies) GDPD PF03009.12 CCC70542.1 - 1.3e-05 24.8 0.0 0.00011 21.8 0.0 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 CCC70543.1 - 2.6e-49 165.4 1.5 1.2e-16 60.7 0.0 3.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCC70543.1 - 8.1e-39 131.3 0.7 6.9e-09 35.9 0.0 4.9 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 CCC70543.1 - 1.1e-33 113.4 0.1 1.8e-07 30.5 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 CCC70543.1 - 1e-31 108.1 0.1 1.8e-09 37.5 0.0 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCC70543.1 - 9.1e-28 93.5 0.0 0.00027 20.8 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Band_7 PF01145.20 CCC70544.1 - 1.8e-22 80.0 0.8 2.7e-22 79.5 0.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Spo12 PF05032.7 CCC70545.1 - 1.3e-16 59.9 6.6 3.5e-16 58.5 4.6 1.8 1 0 0 1 1 1 1 Spo12 family SMI1_KNR4 PF09346.5 CCC70546.1 - 5.3e-35 120.2 0.0 5.3e-35 120.2 0.0 2.6 3 1 0 3 3 3 1 SMI1 / KNR4 family (SUKH-1) DIE2_ALG10 PF04922.7 CCC70547.1 - 2.1e-125 418.7 39.4 3e-125 418.1 27.3 1.2 1 0 0 1 1 1 1 DIE2/ALG10 family WD40 PF00400.27 CCC70548.1 - 1.9e-16 59.2 5.8 6.5e-05 22.6 0.1 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCC70548.1 - 0.00093 18.9 0.1 2.5 7.9 0.0 3.9 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region ESPR PF13018.1 CCC70548.1 - 0.069 12.7 1.9 0.95 9.1 0.1 2.8 3 0 0 3 3 3 0 Extended Signal Peptide of Type V secretion system DUF3312 PF11768.3 CCC70548.1 - 0.074 11.2 0.0 0.33 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) GSHPx PF00255.14 CCC70549.1 - 4.8e-49 164.2 0.3 6.3e-49 163.8 0.2 1.2 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CCC70549.1 - 3.4e-06 26.7 0.1 1.5e-05 24.6 0.1 1.9 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCC70549.1 - 3.2e-05 23.4 0.1 0.00017 21.1 0.1 2.0 1 1 0 1 1 1 1 Redoxin PA PF02225.17 CCC70549.1 - 0.011 15.4 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 PA domain DUF4174 PF13778.1 CCC70549.1 - 0.04 14.0 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Collagen PF01391.13 CCC70550.1 - 4.2e-08 32.6 52.5 4.6e-07 29.2 20.6 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) DUF3822 PF12864.2 CCC70551.1 - 0.0075 15.5 0.2 0.06 12.5 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3822) WD40 PF00400.27 CCC70551.1 - 0.012 15.4 0.0 4.7 7.2 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat BetR PF08667.5 CCC70551.1 - 0.015 15.2 0.1 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 BetR domain Smg4_UPF3 PF03467.10 CCC70552.1 - 0.15 12.0 6.1 0.06 13.3 0.6 2.5 2 1 1 3 3 3 0 Smg-4/UPF3 family SKG6 PF08693.5 CCC70553.1 - 0.0015 17.8 0.7 0.0035 16.6 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Rax2 PF12768.2 CCC70553.1 - 0.0021 17.3 0.0 0.0021 17.3 0.0 2.0 2 0 0 2 2 2 1 Cortical protein marker for cell polarity EphA2_TM PF14575.1 CCC70553.1 - 0.12 12.8 0.0 0.35 11.3 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.1 CCC70553.1 - 0.8 9.8 0.0 0.8 9.8 0.0 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator EF-hand_like PF09279.6 CCC70554.1 - 0.047 13.7 0.6 0.95 9.5 0.1 2.6 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like HLH PF00010.21 CCC70555.1 - 5.7e-22 77.1 0.7 1.2e-21 76.1 0.5 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain HALZ PF02183.13 CCC70555.1 - 2.5 7.8 7.6 0.16 11.7 1.1 2.2 2 0 0 2 2 2 0 Homeobox associated leucine zipper TGS PF02824.16 CCC70556.1 - 1.5e-21 75.9 0.1 2.9e-21 75.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 CCC70556.1 - 1.1e-17 64.0 0.1 2.5e-17 62.8 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCC70556.1 - 4.3e-10 39.0 0.1 1.2e-09 37.6 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCC70556.1 - 0.0011 18.7 0.5 1 9.1 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 CCC70556.1 - 0.0049 16.3 0.1 11 5.3 0.0 3.7 2 2 1 3 3 3 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CCC70556.1 - 0.0065 16.9 0.0 0.016 15.6 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 CCC70556.1 - 0.0066 15.2 0.2 0.015 14.0 0.1 1.6 1 0 0 1 1 1 1 ArgK protein AAA_22 PF13401.1 CCC70556.1 - 0.027 14.6 0.3 1.3 9.1 0.2 2.7 2 1 0 2 2 2 0 AAA domain Arf PF00025.16 CCC70556.1 - 0.052 12.7 0.2 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_28 PF13521.1 CCC70556.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_pol_Rpb1_5 PF04998.12 CCC70557.1 - 3.3e-100 334.9 2.5 1.5e-99 332.7 0.1 3.0 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 CCC70557.1 - 1.8e-65 219.9 0.2 7.7e-65 217.8 0.1 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CCC70557.1 - 8.9e-41 139.2 0.1 6.4e-39 133.2 0.0 3.4 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CCC70557.1 - 5.2e-24 84.0 2.7 8.8e-24 83.3 0.0 3.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_1 PF04997.7 CCC70557.1 - 2.2e-20 73.2 0.5 2.2e-20 73.2 0.3 5.0 4 1 0 4 4 4 1 RNA polymerase Rpb1, domain 1 FYDLN_acid PF09538.5 CCC70557.1 - 0.31 11.6 16.5 5.6 7.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Mis12 PF05859.7 CCC70558.1 - 2.9e-45 153.6 4.2 2.9e-45 153.6 2.9 1.8 2 1 0 2 2 2 1 Mis12 protein PRTase_3 PF15610.1 CCC70558.1 - 0.022 13.6 0.1 0.03 13.2 0.1 1.2 1 0 0 1 1 1 0 PRTase ComF-like SWIRM PF04433.12 CCC70559.1 - 1.2e-14 54.2 0.0 3.2e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 SWIRM domain NT-C2 PF10358.4 CCC70559.1 - 0.0091 15.4 0.0 0.024 14.1 0.0 1.7 2 0 0 2 2 2 1 N-terminal C2 in EEIG1 and EHBP1 proteins bZIP_2 PF07716.10 CCC70561.1 - 9.5e-10 38.1 7.4 9.5e-10 38.1 5.1 3.2 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.16 CCC70561.1 - 0.00013 21.8 13.0 0.00013 21.8 9.0 3.4 3 1 1 4 4 4 2 bZIP transcription factor TSC22 PF01166.13 CCC70561.1 - 0.12 12.3 0.3 0.12 12.3 0.2 3.2 3 1 0 3 3 3 0 TSC-22/dip/bun family bZIP_Maf PF03131.12 CCC70561.1 - 0.49 10.7 14.9 0.16 12.2 8.4 1.7 2 1 0 2 2 2 0 bZIP Maf transcription factor Allexi_40kDa PF05549.6 CCC70561.1 - 2.3 7.4 10.4 4.8 6.3 7.1 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein FlaC_arch PF05377.6 CCC70561.1 - 5.4 6.9 8.7 2.9 7.8 0.6 3.1 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Mu-like_Pro PF10123.4 CCC70561.1 - 8.2 5.7 10.1 6.1 6.2 5.4 1.7 1 1 1 2 2 2 0 Mu-like prophage I protein DUF2681 PF10883.3 CCC70561.1 - 9.2 6.5 19.5 7.3 6.8 3.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) Mannosyl_trans3 PF11051.3 CCC70562.1 - 1.6e-66 224.4 0.1 2.8e-66 223.6 0.1 1.4 1 0 0 1 1 1 1 Mannosyltransferase putative ABC2_membrane PF01061.19 CCC70563.1 - 2.3e-66 222.9 66.8 3.5e-35 121.0 20.6 3.2 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 CCC70563.1 - 4.2e-28 97.0 13.0 5.7e-24 83.7 0.1 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 CCC70563.1 - 1.7e-27 96.3 0.0 6.4e-15 55.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 CCC70563.1 - 5e-05 22.5 0.1 0.00011 21.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 CCC70563.1 - 0.00032 19.8 64.1 0.0055 15.7 11.2 4.1 2 2 1 3 3 3 2 ABC-2 family transporter protein SMC_N PF02463.14 CCC70563.1 - 0.0031 16.7 0.1 0.32 10.2 0.0 2.5 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCC70563.1 - 0.0044 17.3 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCC70563.1 - 0.0077 16.3 0.1 0.023 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCC70563.1 - 0.027 14.7 0.0 0.098 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 CCC70563.1 - 0.028 14.3 0.6 0.083 12.8 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 CCC70563.1 - 0.037 13.5 0.3 0.11 12.0 0.2 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 CCC70563.1 - 0.037 13.4 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 CCC70563.1 - 0.16 11.7 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 CCC70563.1 - 0.46 10.3 28.3 0.18 11.7 0.1 5.5 5 1 1 6 6 6 0 AAA domain SRP1_TIP1 PF00660.12 CCC70564.1 - 6.1e-35 119.1 2.1 2e-34 117.5 1.4 1.9 1 0 0 1 1 1 1 Seripauperin and TIP1 family DDHD PF02862.12 CCC70564.1 - 0.00026 20.8 9.4 0.00036 20.4 6.5 1.3 1 0 0 1 1 1 1 DDHD domain CDC27 PF09507.5 CCC70564.1 - 0.064 12.4 18.0 0.075 12.2 12.5 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Hex_IIIa PF02455.11 CCC70564.1 - 0.58 8.7 6.6 0.67 8.5 4.6 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) PTS_EIIC PF02378.13 CCC70564.1 - 1.3 7.7 9.2 3 6.5 6.4 1.7 1 1 0 1 1 1 0 Phosphotransferase system, EIIC Macoilin PF09726.4 CCC70564.1 - 1.8 6.7 33.6 2.3 6.3 23.3 1.1 1 0 0 1 1 1 0 Transmembrane protein SRP-alpha_N PF04086.8 CCC70564.1 - 4.4 6.6 15.6 6 6.1 10.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF936 PF06075.7 CCC70564.1 - 5.3 5.8 25.6 6.4 5.5 17.7 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) AhpC-TSA PF00578.16 CCC70565.1 - 3.9e-27 94.4 0.0 5.7e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCC70565.1 - 3.7e-18 65.4 0.0 5.9e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Redoxin DUF1644 PF07800.7 CCC70565.1 - 0.03 14.1 0.1 0.042 13.6 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) DUF1372 PF07116.6 CCC70565.1 - 0.099 12.6 0.6 0.21 11.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1372) AAA PF00004.24 CCC70566.1 - 2.2e-10 40.8 0.2 1.6e-09 38.0 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 CCC70566.1 - 3.3e-07 29.3 7.3 2.2e-05 23.3 0.0 3.2 4 0 0 4 4 4 2 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 CCC70566.1 - 1.3e-05 25.9 0.1 0.00011 22.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCC70566.1 - 4.6e-05 23.5 0.3 0.00091 19.3 0.2 3.1 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 CCC70566.1 - 9.2e-05 22.3 0.0 9.2e-05 22.3 0.0 2.5 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 CCC70566.1 - 0.00037 19.6 0.0 0.001 18.2 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCC70566.1 - 0.0008 19.4 0.0 0.0022 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CCC70566.1 - 0.002 18.4 0.4 0.026 14.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 CCC70566.1 - 0.0022 17.6 0.2 0.02 14.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCC70566.1 - 0.0045 16.8 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCC70566.1 - 0.0078 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 CCC70566.1 - 0.015 15.4 0.0 0.075 13.2 0.0 2.3 2 0 0 2 2 2 0 RNA helicase IPT PF01745.11 CCC70566.1 - 0.024 13.7 0.1 0.077 12.1 0.0 1.8 2 0 0 2 2 2 0 Isopentenyl transferase DUF258 PF03193.11 CCC70566.1 - 0.026 13.6 0.0 0.076 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 CCC70566.1 - 0.061 12.7 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein CRAL_TRIO PF00650.15 CCC70567.1 - 5.7e-35 120.1 0.0 7.1e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 CCC70567.1 - 0.02 14.7 0.0 0.049 13.5 0.0 1.6 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain HEAT PF02985.17 CCC70568.1 - 7e-06 25.6 0.0 0.45 10.7 0.0 5.6 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 CCC70568.1 - 0.00068 19.8 0.0 0.56 10.5 0.0 4.4 4 2 0 4 4 4 1 HEAT repeats PHD PF00628.24 CCC70569.1 - 1.6e-13 50.0 19.3 2.8e-10 39.7 6.1 2.8 2 1 1 3 3 3 2 PHD-finger zf-HC5HC2H PF13771.1 CCC70569.1 - 0.025 14.7 6.6 0.079 13.1 1.0 2.6 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.1 CCC70569.1 - 0.026 13.8 4.5 0.66 9.2 0.1 3.0 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 CCC70569.1 - 0.055 13.2 9.7 0.27 10.9 0.4 2.6 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RanBP PF00641.13 CCC70569.1 - 0.083 12.0 2.2 0.31 10.1 0.3 2.9 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others dsDNA_bind PF01984.15 CCC70570.1 - 8.1e-29 99.7 0.1 9.7e-29 99.5 0.1 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain Pfg27 PF09216.5 CCC70570.1 - 0.038 13.5 0.2 0.047 13.2 0.1 1.1 1 0 0 1 1 1 0 Pfg27 Cyt-b5 PF00173.23 CCC70571.1 - 7.9e-18 64.0 0.0 1.1e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HMG_box PF00505.14 CCC70572.1 - 1.8e-36 124.2 11.7 2.9e-19 69.0 3.6 2.5 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_2 PF09011.5 CCC70572.1 - 9e-23 80.4 4.4 8.4e-14 51.6 2.8 2.2 2 0 0 2 2 2 2 HMG-box domain CHDNT PF08073.7 CCC70572.1 - 5.2e-06 26.0 0.0 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 2 CHDNT (NUC034) domain Tol_Tol_Ttg2 PF05494.7 CCC70572.1 - 0.088 12.3 0.1 12 5.3 0.0 2.5 2 1 0 2 2 2 0 Toluene tolerance, Ttg2 Cg6151-P PF10233.4 CCC70573.1 - 1.3e-39 134.6 15.4 1.6e-39 134.3 10.7 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P zf-C2H2 PF00096.21 CCC70574.1 - 1.2e-06 28.4 14.3 1.6e-05 24.9 2.3 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC70574.1 - 2.9e-05 24.0 3.1 2.9e-05 24.0 2.1 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 CCC70574.1 - 0.003 17.6 2.8 0.0068 16.5 1.9 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-FCS PF06467.9 CCC70574.1 - 0.14 11.8 2.2 0.34 10.5 1.6 1.6 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif zf-RING_2 PF13639.1 CCC70574.1 - 0.61 9.9 3.5 1.1 9.0 2.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-H2C2_2 PF13465.1 CCC70574.1 - 5.1 7.5 13.8 7.4 7.0 2.7 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-H2C2_2 PF13465.1 CCC70575.1 - 0.00014 22.0 5.8 0.0011 19.1 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC70575.1 - 0.00015 21.8 5.5 0.0019 18.3 0.2 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 CCC70575.1 - 0.00015 21.9 10.4 0.00089 19.4 0.5 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type SR-25 PF10500.4 CCC70575.1 - 0.0012 18.3 9.2 0.0012 18.3 6.4 1.6 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein zf-C2H2_jaz PF12171.3 CCC70575.1 - 0.019 15.1 0.5 0.11 12.7 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCC70575.1 - 0.029 14.5 4.2 0.14 12.3 0.3 2.6 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF2180 PF09947.4 CCC70575.1 - 0.031 14.0 0.1 0.064 13.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2180) zf-BED PF02892.10 CCC70575.1 - 3.4 7.5 8.7 2.4 7.9 1.9 2.5 2 0 0 2 2 2 0 BED zinc finger zf-H2C2_2 PF13465.1 CCC70576.1 - 4.6e-07 29.8 8.0 4.9e-05 23.4 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CCC70576.1 - 1.5e-06 28.1 7.5 0.0013 18.9 0.5 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC70576.1 - 0.00089 19.4 8.8 0.0023 18.1 0.3 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger PRP21_like_P PF12230.3 CCC70576.1 - 0.0033 16.9 2.9 0.0033 16.9 2.0 1.9 2 1 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein GAGA PF09237.6 CCC70576.1 - 0.0048 16.4 0.3 0.013 15.1 0.2 1.7 1 0 0 1 1 1 1 GAGA factor zf-met PF12874.2 CCC70576.1 - 0.0052 16.9 5.0 0.01 16.0 0.2 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 CCC70576.1 - 0.036 14.2 1.2 0.24 11.5 0.0 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Trypan_PARP PF05887.6 CCC70576.1 - 0.54 10.0 4.0 1.1 9.0 2.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Neisseria_TspB PF05616.8 CCC70576.1 - 1.4 7.1 10.3 2.5 6.3 7.2 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein zf-H2C2_5 PF13909.1 CCC70576.1 - 2.3 8.6 6.9 11 6.5 0.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Mito_carr PF00153.22 CCC70578.1 - 8.5e-61 201.6 0.4 1.9e-20 72.3 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L14e PF01929.12 CCC70579.1 - 5.6e-31 106.7 0.7 9e-31 106.0 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 CCC70579.1 - 4.4e-05 23.0 0.4 8.8e-05 22.0 0.3 1.5 1 0 0 1 1 1 1 KOW motif Oxysterol_BP PF01237.13 CCC70580.1 - 2.2e-88 296.1 0.0 2.8e-88 295.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein CENP-O PF09496.5 CCC70580.1 - 0.054 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component TRAM_LAG1_CLN8 PF03798.11 CCC70581.1 - 5.7e-35 120.6 24.9 5.7e-35 120.6 17.3 2.4 2 1 0 2 2 2 1 TLC domain TRAM1 PF08390.6 CCC70581.1 - 3.6e-25 87.2 1.1 3.6e-25 87.2 0.8 2.3 2 0 0 2 2 2 1 TRAM1-like protein PQ-loop PF04193.9 CCC70582.1 - 4.7e-08 32.4 8.1 1e-07 31.3 1.9 4.3 4 1 1 5 5 5 2 PQ loop repeat ARD PF03079.9 CCC70583.1 - 1.4e-42 145.2 0.4 1.7e-42 145.0 0.3 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 CCC70583.1 - 1.7e-10 40.2 0.0 3.2e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 CCC70583.1 - 2.5e-06 27.1 0.0 3.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 CCC70583.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_8 PF13621.1 CCC70583.1 - 0.018 14.5 0.0 0.058 12.8 0.0 1.6 1 1 1 2 2 2 0 Cupin-like domain JmjC PF02373.17 CCC70583.1 - 0.091 13.0 0.1 0.35 11.1 0.0 1.9 1 1 0 1 1 1 0 JmjC domain, hydroxylase bZIP_1 PF00170.16 CCC70584.1 - 0.00014 21.7 13.6 0.00014 21.7 9.4 3.4 2 1 1 3 3 3 1 bZIP transcription factor Hap4_Hap_bind PF10297.4 CCC70584.1 - 0.0012 18.6 3.8 0.0026 17.5 0.6 2.5 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_Maf PF03131.12 CCC70584.1 - 0.019 15.2 9.6 0.062 13.6 6.6 1.9 1 0 0 1 1 1 0 bZIP Maf transcription factor Phage_Orf51 PF06194.6 CCC70584.1 - 0.05 13.6 0.7 0.11 12.6 0.2 1.8 2 0 0 2 2 2 0 Phage Conserved Open Reading Frame 51 DUF3584 PF12128.3 CCC70584.1 - 0.21 8.8 8.4 0.31 8.3 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 CCC70584.1 - 0.28 10.9 2.4 0.42 10.4 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) NBP1 PF08537.5 CCC70584.1 - 2.3 7.3 15.8 0.13 11.4 6.9 1.8 2 0 0 2 2 2 0 Fungal Nap binding protein NBP1 V_ATPase_I PF01496.14 CCC70584.1 - 3.2 5.4 4.6 5.1 4.8 3.2 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Renin_r PF07850.9 CCC70585.1 - 0.084 13.2 0.7 0.084 13.2 0.5 1.9 2 0 0 2 2 2 0 Renin receptor-like protein Rpr2 PF04032.11 CCC70586.1 - 2.6e-18 65.6 3.1 3.8e-18 65.1 2.1 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain TSC22 PF01166.13 CCC70586.1 - 0.098 12.6 0.2 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family Proteasome PF00227.21 CCC70587.1 - 9.6e-56 188.0 0.0 1.2e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCC70587.1 - 7.1e-14 50.8 0.1 1.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature APC_CDC26 PF10471.4 CCC70587.1 - 0.0098 16.6 3.9 0.02 15.5 2.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 Helicase_C_3 PF13625.1 CCC70587.1 - 0.089 12.5 0.1 0.46 10.2 0.0 2.1 3 0 0 3 3 3 0 Helicase conserved C-terminal domain RNase_P_Rpp14 PF01900.14 CCC70588.1 - 9.5e-32 109.0 0.1 1.3e-31 108.7 0.1 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Cellulase PF00150.13 CCC70589.1 - 3.1e-15 56.1 0.3 4.2e-10 39.3 0.1 3.1 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 CCC70589.1 - 0.019 14.3 0.0 0.043 13.1 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 DNA_primase_S PF01896.14 CCC70590.1 - 1.5e-52 177.2 0.3 2.8e-52 176.3 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit Zn_clus PF00172.13 CCC70591.1 - 5.6e-08 32.5 7.3 1.1e-07 31.6 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AMPKBI PF04739.10 CCC70593.1 - 2e-26 91.8 7.4 2.7e-26 91.3 1.9 3.3 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain PAP1 PF08601.5 CCC70594.1 - 6.3e-11 42.5 50.9 2.5e-08 34.0 34.6 3.3 1 1 0 1 1 1 1 Transcription factor PAP1 bZIP_1 PF00170.16 CCC70594.1 - 1.1e-06 28.4 7.3 2.7e-06 27.2 5.1 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCC70594.1 - 0.0028 17.4 10.3 0.0067 16.2 7.2 1.7 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CCC70594.1 - 1.3 9.4 10.4 0.04 14.1 2.5 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor Dynein_light PF01221.13 CCC70595.1 - 6.7e-35 118.9 0.0 8.1e-35 118.6 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 CCC70595.1 - 0.00044 20.5 0.0 0.00058 20.1 0.0 1.1 1 0 0 1 1 1 1 Ground-like domain PCI PF01399.22 CCC70596.1 - 5.1e-13 49.2 3.6 5.4e-13 49.1 0.3 2.3 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 CCC70596.1 - 0.0018 18.0 3.7 0.011 15.5 0.3 2.5 2 0 0 2 2 2 2 COP9 signalosome, subunit CSN8 EMP24_GP25L PF01105.19 CCC70597.1 - 3.5e-42 144.2 0.0 4.2e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD M16C_assoc PF08367.6 CCC70598.1 - 1.6e-75 253.1 1.2 2.9e-75 252.3 0.8 1.4 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 CCC70598.1 - 1.5e-31 109.5 0.2 1.1e-16 61.0 0.0 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 CCC70598.1 - 1.2e-07 31.6 0.1 9.3e-07 28.7 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) RRM_1 PF00076.17 CCC70599.1 - 3.3e-30 103.5 0.6 1.1e-17 63.3 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC70599.1 - 6.6e-17 61.2 0.0 2e-11 43.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC70599.1 - 2.7e-14 52.7 0.0 4e-10 39.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WWbp PF10349.4 CCC70599.1 - 0.0015 19.4 3.7 0.0015 19.4 2.5 3.8 2 2 1 3 3 3 2 WW-domain ligand protein RNA_bind PF08675.6 CCC70599.1 - 0.053 13.4 0.0 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 RNA binding domain PIG-S PF10510.4 CCC70600.1 - 4.9e-138 461.0 11.2 6.3e-138 460.6 7.7 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein TAFII28 PF04719.9 CCC70601.1 - 2.7e-25 87.9 0.1 2.1e-23 81.9 0.1 2.5 2 0 0 2 2 2 2 hTAFII28-like protein conserved region LCM PF04072.9 CCC70602.1 - 4.7e-25 88.2 0.0 6.5e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF2529 PF10740.4 CCC70602.1 - 0.1 12.0 0.1 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2529) PIG-P PF08510.7 CCC70603.1 - 9.3e-29 99.6 3.6 1.4e-28 99.0 2.5 1.3 1 0 0 1 1 1 1 PIG-P CCSMST1 PF15013.1 CCC70603.1 - 0.077 12.9 0.3 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 CCSMST1 family DUF624 PF04854.9 CCC70603.1 - 3.7 7.4 6.5 0.23 11.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF624 TPT PF03151.11 CCC70604.1 - 4.3e-10 39.4 29.6 4.8e-07 29.5 6.5 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 CCC70604.1 - 3.3e-09 36.8 40.0 7e-07 29.3 6.0 3.2 2 1 1 3 3 3 3 EamA-like transporter family UAA PF08449.6 CCC70604.1 - 8.1e-08 31.5 25.2 7.9e-06 24.9 13.8 2.0 1 1 1 2 2 2 2 UAA transporter family DUF914 PF06027.7 CCC70604.1 - 7.2e-06 25.0 7.9 7.2e-06 25.0 5.5 1.5 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 CCC70604.1 - 0.005 17.0 3.4 0.005 17.0 2.3 3.8 2 2 2 4 4 4 1 Multidrug resistance efflux transporter LRS4 PF10422.4 CCC70605.1 - 2.3e-22 79.5 26.8 9.6e-20 70.9 18.5 2.4 1 1 0 1 1 1 1 Monopolin complex subunit LRS4 FlxA PF14282.1 CCC70605.1 - 0.00084 19.2 15.9 0.00084 19.2 11.0 1.8 2 0 0 2 2 2 1 FlxA-like protein Dsl1_C PF11989.3 CCC70605.1 - 0.0053 15.9 1.9 0.0053 15.9 1.3 1.6 2 0 0 2 2 2 1 Retrograde transport protein Dsl1 C terminal FlgN PF05130.7 CCC70605.1 - 0.013 15.6 5.5 0.023 14.9 3.8 1.4 1 0 0 1 1 1 0 FlgN protein DUF2509 PF10713.4 CCC70605.1 - 0.063 13.0 0.6 0.1 12.3 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2509) TBCA PF02970.11 CCC70605.1 - 0.08 13.0 6.6 0.22 11.6 4.6 1.8 1 0 0 1 1 1 0 Tubulin binding cofactor A Allexi_40kDa PF05549.6 CCC70605.1 - 0.17 11.1 6.7 0.27 10.4 4.7 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein PUD PF03714.9 CCC70605.1 - 0.19 11.8 0.2 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 Bacterial pullanase-associated domain DUF4110 PF13422.1 CCC70605.1 - 0.21 11.4 5.6 0.17 11.7 2.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) DUF3573 PF12097.3 CCC70605.1 - 0.47 9.0 4.9 0.59 8.6 3.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Lipase PF00151.14 CCC70605.1 - 0.52 9.4 3.8 0.75 8.9 2.7 1.2 1 0 0 1 1 1 0 Lipase Poty_PP PF08440.5 CCC70605.1 - 0.64 9.0 7.2 0.86 8.6 5.0 1.2 1 0 0 1 1 1 0 Potyviridae polyprotein TSC22 PF01166.13 CCC70605.1 - 0.65 10.0 7.6 0.25 11.3 2.8 2.2 2 1 0 2 2 2 0 TSC-22/dip/bun family IncA PF04156.9 CCC70605.1 - 1.9 8.0 11.7 0.29 10.6 5.6 1.5 2 0 0 2 2 2 0 IncA protein DOT1 PF08123.8 CCC70606.1 - 1e-84 282.9 0.4 1.7e-84 282.2 0.3 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Med13_C PF06333.7 CCC70607.1 - 4.5e-89 298.9 0.9 2.6e-57 194.2 0.6 2.4 1 1 1 2 2 2 2 Mediator complex subunit 13 C-terminal DUF676 PF05057.9 CCC70608.1 - 1.3e-54 184.7 0.0 2.2e-54 184.0 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 CCC70608.1 - 1.3e-05 24.7 0.0 5.8e-05 22.7 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) DUF915 PF06028.6 CCC70608.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) ECM11 PF15463.1 CCC70611.1 - 1.1e-29 103.5 0.0 1.1e-29 103.5 0.0 2.8 1 1 1 2 2 2 1 Extracellular mutant protein 11 Ribosomal_S17e PF00833.13 CCC70612.1 - 9.7e-57 190.0 0.3 1.2e-56 189.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 ZZ PF00569.12 CCC70613.1 - 8.8e-16 57.1 11.7 9.9e-16 57.0 5.6 2.3 2 0 0 2 2 2 1 Zinc finger, ZZ type SWIRM PF04433.12 CCC70613.1 - 2.2e-08 34.0 0.1 6.3e-07 29.4 0.0 2.6 2 0 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.26 CCC70613.1 - 5.1e-07 29.6 0.0 1.4e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCC70613.1 - 0.00056 19.9 0.5 0.0026 17.8 0.0 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain U3_assoc_6 PF08640.6 CCC70614.1 - 2.3e-32 110.5 1.0 2.3e-32 110.5 0.7 3.3 3 1 0 3 3 3 2 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 CCC70614.1 - 0.00026 19.9 6.7 0.0028 16.5 0.9 3.2 2 1 1 3 3 3 2 NRDE-2, necessary for RNA interference DUF2250 PF10007.4 CCC70614.1 - 0.0013 18.5 2.7 0.24 11.3 0.0 3.6 3 0 0 3 3 3 1 Uncharacterized protein conserved in archaea (DUF2250) Suf PF05843.9 CCC70614.1 - 0.0026 17.5 4.4 0.0026 17.5 3.1 3.4 1 1 0 2 2 2 1 Suppressor of forked protein (Suf) TPR_14 PF13428.1 CCC70614.1 - 0.048 14.3 0.0 7.6 7.4 0.0 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCC70614.1 - 0.057 13.6 0.9 4.3 7.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat HAT PF02184.11 CCC70614.1 - 0.14 11.8 0.9 0.89 9.3 0.1 2.4 2 0 0 2 2 2 0 HAT (Half-A-TPR) repeat Ribosomal_S13 PF00416.17 CCC70615.1 - 1.7e-42 144.2 2.2 2e-42 143.9 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CCC70615.1 - 0.00062 18.4 0.0 0.0008 18.0 0.0 1.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 CCC70615.1 - 0.085 12.9 0.3 0.6 10.2 0.1 2.2 2 1 0 2 2 2 0 Helix-hairpin-helix motif Metallophos PF00149.23 CCC70616.1 - 3.2e-11 42.9 1.0 9.3e-11 41.4 0.6 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AhpC-TSA PF00578.16 CCC70617.1 - 1.5e-34 118.3 0.0 4.1e-33 113.7 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CCC70617.1 - 7.4e-18 64.4 0.0 1.3e-17 63.6 0.0 1.4 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.4 CCC70617.1 - 9.6e-09 34.7 0.3 1.8e-08 33.8 0.2 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Guanylate_kin PF00625.16 CCC70618.1 - 1.1e-69 233.5 0.0 1.2e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 CCC70618.1 - 1e-07 31.9 0.0 6.1e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCC70618.1 - 3.4e-07 30.4 0.1 4.4e-05 23.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCC70618.1 - 1.1e-06 29.4 0.1 3.1e-06 28.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCC70618.1 - 2.4e-06 27.8 0.1 7.1e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC70618.1 - 2.8e-06 27.4 0.2 1.8e-05 24.8 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 CCC70618.1 - 0.00012 22.3 0.0 0.00027 21.2 0.0 1.6 1 1 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 CCC70618.1 - 0.0004 20.5 0.0 0.0015 18.7 0.0 1.9 2 1 0 2 2 2 1 RNA helicase AAA_14 PF13173.1 CCC70618.1 - 0.0004 20.2 0.0 0.001 18.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.1 CCC70618.1 - 0.00043 19.9 0.3 0.019 14.5 0.0 2.1 1 1 1 2 2 2 1 AAA domain Miro PF08477.8 CCC70618.1 - 0.00044 20.7 0.0 0.0012 19.3 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein AAA_28 PF13521.1 CCC70618.1 - 0.00055 19.9 0.0 0.0013 18.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 CCC70618.1 - 0.00066 18.8 0.0 0.00098 18.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 CCC70618.1 - 0.00075 19.4 0.0 0.0023 17.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 CCC70618.1 - 0.00092 18.9 0.2 0.0029 17.3 0.1 2.0 1 1 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 CCC70618.1 - 0.0012 18.4 0.0 0.0035 17.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 CCC70618.1 - 0.0017 17.3 0.0 0.007 15.3 0.0 1.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 CCC70618.1 - 0.0031 17.6 0.4 0.015 15.5 0.0 2.0 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCC70618.1 - 0.004 16.8 0.0 0.0097 15.5 0.0 1.6 2 0 0 2 2 2 1 NACHT domain T2SE PF00437.15 CCC70618.1 - 0.0053 15.6 0.4 0.0096 14.8 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 CCC70618.1 - 0.0054 16.2 0.1 0.011 15.1 0.1 1.5 1 0 0 1 1 1 1 AAA-like domain AAA_2 PF07724.9 CCC70618.1 - 0.0056 16.6 0.1 0.34 10.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) KAP_NTPase PF07693.9 CCC70618.1 - 0.0063 15.5 0.0 0.013 14.4 0.0 1.5 1 1 0 1 1 1 1 KAP family P-loop domain AAA_25 PF13481.1 CCC70618.1 - 0.007 15.7 0.1 0.027 13.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 CCC70618.1 - 0.0083 15.6 0.0 0.03 13.8 0.0 1.8 1 1 1 2 2 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 CCC70618.1 - 0.011 15.4 0.1 0.023 14.3 0.0 1.6 2 0 0 2 2 1 0 NTPase AAA_29 PF13555.1 CCC70618.1 - 0.011 15.1 0.5 0.011 15.1 0.4 2.2 2 1 0 2 2 2 0 P-loop containing region of AAA domain AAA_30 PF13604.1 CCC70618.1 - 0.012 15.1 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CCC70618.1 - 0.02 14.3 0.1 0.076 12.4 0.0 1.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 CCC70618.1 - 0.033 13.8 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 CCC70618.1 - 0.041 12.5 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_21 PF13304.1 CCC70618.1 - 0.054 13.4 0.0 0.1 12.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain VirE PF05272.6 CCC70618.1 - 0.074 12.5 0.5 0.5 9.8 0.1 2.3 2 1 0 2 2 1 0 Virulence-associated protein E AAA_23 PF13476.1 CCC70618.1 - 0.083 13.2 4.5 0.21 11.9 3.1 2.0 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 CCC70618.1 - 0.093 12.0 0.0 0.52 9.6 0.0 1.9 1 1 1 2 2 2 0 Thymidylate kinase UPF0079 PF02367.12 CCC70618.1 - 0.095 12.3 0.3 0.26 10.9 0.0 1.8 2 1 1 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 CCC70618.1 - 0.1 11.4 0.0 0.2 10.4 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 CCC70618.1 - 0.13 12.0 0.1 0.5 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) FeoB_N PF02421.13 CCC70618.1 - 0.13 11.4 0.0 7.6 5.8 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B Na_H_Exchanger PF00999.16 CCC70619.1 - 8.4e-68 228.6 34.5 1.1e-67 228.2 23.9 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Myc_target_1 PF15179.1 CCC70619.1 - 3.9 7.0 9.4 0.19 11.3 0.6 2.8 3 0 0 3 3 3 0 Myc target protein 1 HECT PF00632.20 CCC70620.1 - 9.9e-94 314.0 0.0 9.9e-94 314.0 0.0 2.4 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 CCC70620.1 - 3.4e-68 230.3 1.4 3.4e-68 230.3 1.0 3.3 3 0 0 3 3 3 1 Domain of Unknown Function (DUF908) DUF913 PF06025.7 CCC70620.1 - 7.2e-36 123.7 5.7 2.3e-35 122.0 0.5 3.1 3 0 0 3 3 3 1 Domain of Unknown Function (DUF913) DUF4414 PF14377.1 CCC70620.1 - 1e-15 57.5 1.1 4.2e-15 55.5 0.7 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4414) zf-C2H2 PF00096.21 CCC70621.1 - 5e-07 29.6 9.8 0.0027 17.9 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC70621.1 - 9.3e-06 25.6 5.0 0.002 18.3 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 CCC70621.1 - 1.3e-05 25.2 8.8 0.0069 16.6 2.4 2.5 2 0 0 2 2 2 2 Zinc-finger double domain DUF629 PF04780.7 CCC70621.1 - 0.0017 16.9 1.2 0.002 16.7 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF629) zf-TRAF PF02176.13 CCC70621.1 - 0.02 15.2 5.1 0.033 14.5 3.5 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_jaz PF12171.3 CCC70621.1 - 0.044 13.9 1.1 0.044 13.9 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Succ_DH_flav_C PF02910.15 CCC70621.1 - 0.073 12.9 0.1 0.094 12.5 0.1 1.1 1 0 0 1 1 1 0 Fumarate reductase flavoprotein C-term DUF1570 PF07607.6 CCC70621.1 - 0.096 12.6 0.1 0.19 11.6 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1570) CXCL17 PF15211.1 CCC70621.1 - 0.22 11.9 4.0 0.32 11.4 2.8 1.3 1 0 0 1 1 1 0 VEGF co-regulated chemokine 1 MSC PF09402.5 CCC70622.1 - 4.7e-73 245.8 5.3 4.7e-73 245.8 3.7 2.6 3 0 0 3 3 3 1 Man1-Src1p-C-terminal domain HeH PF12949.2 CCC70622.1 - 8.7e-14 50.7 1.7 2e-13 49.6 1.2 1.7 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.22 CCC70622.1 - 0.017 14.6 0.2 0.039 13.4 0.1 1.6 1 0 0 1 1 1 0 SAP domain zf-DHHC PF01529.15 CCC70623.1 - 1.8e-26 92.5 8.1 1.8e-26 92.5 5.6 2.5 2 1 0 3 3 3 1 DHHC palmitoyltransferase BAF1_ABF1 PF04684.8 CCC70624.1 - 1.6e-83 281.2 83.7 1.1e-51 176.2 18.6 5.8 2 1 2 5 5 5 3 BAF1 / ABF1 chromatin reorganising factor DBD_Tnp_Mut PF03108.10 CCC70624.1 - 0.017 14.7 0.6 0.04 13.4 0.4 1.6 1 0 0 1 1 1 0 MuDR family transposase YebO PF13974.1 CCC70624.1 - 0.6 9.9 6.4 0.91 9.3 0.0 3.8 2 1 1 3 3 3 0 YebO-like protein XPG_N PF00752.12 CCC70625.1 - 2.4e-39 133.6 0.0 4.8e-39 132.6 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 CCC70625.1 - 2.1e-28 98.1 0.0 4.9e-28 97.0 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 CCC70625.1 - 5.8e-08 32.8 0.6 4.5e-07 30.0 0.0 2.5 2 1 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 CCC70625.1 - 0.00042 19.7 0.1 0.0028 17.0 0.0 2.1 1 1 1 2 2 2 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_2 PF12826.2 CCC70625.1 - 0.098 12.5 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH_5 PF14520.1 CCC70625.1 - 0.67 10.1 3.4 1.1 9.4 0.6 2.7 2 1 0 2 2 2 0 Helix-hairpin-helix domain Aldose_epim PF01263.15 CCC70626.1 - 3.2e-48 164.3 0.3 3.8e-48 164.1 0.2 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase iPGM_N PF06415.8 CCC70626.1 - 0.028 13.7 0.1 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 BPG-independent PGAM N-terminus (iPGM_N) zf-MYND PF01753.13 CCC70627.1 - 4.5e-07 29.6 21.7 1.3e-06 28.1 15.0 1.8 1 1 0 1 1 1 1 MYND finger Prenyltransf PF01255.14 CCC70628.1 - 9.5e-70 234.1 0.2 1.4e-69 233.6 0.1 1.2 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase WD40 PF00400.27 CCC70629.1 - 1.7e-21 75.2 25.8 5.6e-09 35.5 0.2 7.3 7 1 0 7 7 7 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCC70629.1 - 0.021 14.6 0.7 2.7 7.8 0.0 3.7 3 2 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF1900 PF08954.6 CCC70629.1 - 0.024 14.1 0.0 0.066 12.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) Pkinase PF00069.20 CCC70630.1 - 4.8e-70 235.6 0.0 7.1e-70 235.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC70630.1 - 3.8e-30 104.8 0.0 5.3e-30 104.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 CCC70630.1 - 3.4e-09 37.0 0.1 9.8e-09 35.6 0.1 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 CCC70630.1 - 0.001 18.1 0.0 0.0021 17.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCC70630.1 - 0.066 12.2 0.1 0.13 11.2 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PGM_PMM_I PF02878.11 CCC70631.1 - 9.7e-37 125.5 0.2 1.9e-36 124.6 0.1 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 CCC70631.1 - 1.1e-25 89.8 0.0 2e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 CCC70631.1 - 1.1e-13 51.4 0.0 2.5e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 CCC70631.1 - 3.5e-11 42.9 0.0 7.5e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Ku PF02735.11 CCC70632.1 - 8.5e-34 116.7 0.0 2e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 CCC70632.1 - 5.5e-18 65.2 3.3 9.2e-18 64.4 2.3 1.3 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain TP6A_N PF04406.9 CCC70633.1 - 5e-12 45.3 0.1 1.1e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase DUF436 PF04260.7 CCC70633.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF436) TPP_enzyme_N PF02776.13 CCC70634.1 - 2.4e-59 199.6 0.8 4.3e-58 195.6 0.1 2.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 CCC70634.1 - 1.5e-49 167.5 0.3 2.7e-48 163.4 0.0 2.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCC70634.1 - 6.8e-38 129.5 2.0 4.3e-37 126.9 0.1 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, central domain Aldedh PF00171.17 CCC70635.1 - 5.4e-79 265.6 0.0 6.6e-79 265.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3447 PF11929.3 CCC70635.1 - 0.0072 16.1 0.6 0.027 14.2 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3447) Cys_Met_Meta_PP PF01053.15 CCC70636.1 - 3.5e-146 486.4 0.0 4e-146 486.2 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.6 CCC70636.1 - 8.5e-06 24.3 0.0 1.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.16 CCC70636.1 - 0.00012 21.1 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.11 CCC70636.1 - 0.011 14.5 0.0 0.017 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Phage_int_SAM_3 PF14659.1 CCC70636.1 - 0.053 13.7 0.2 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain Ribosomal_S19 PF00203.16 CCC70637.1 - 5.5e-32 109.2 0.0 8.7e-32 108.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 CCC70637.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Flagellar assembly protein FliH Sds3 PF08598.6 CCC70638.1 - 1.2e-45 155.5 2.8 1.2e-45 155.5 1.9 2.4 2 0 0 2 2 2 1 Sds3-like SNARE PF05739.14 CCC70639.1 - 2.9e-10 39.6 1.6 8.4e-10 38.2 1.1 1.9 1 0 0 1 1 1 1 SNARE domain SHP PF03579.8 CCC70639.1 - 1.1 8.6 4.9 11 5.4 1.6 2.5 2 0 0 2 2 2 0 Small hydrophobic protein FliT PF05400.8 CCC70639.1 - 4.3 7.8 7.5 4.4 7.7 0.1 3.5 4 1 0 4 4 4 0 Flagellar protein FliT HhH-GPD PF00730.20 CCC70640.1 - 2.1e-24 85.8 0.0 4.3e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 CCC70640.1 - 3.4e-06 26.4 0.4 3.2e-05 23.3 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix motif Ribosomal_L6e PF01159.14 CCC70640.1 - 1.2 9.4 8.4 0.26 11.5 2.8 2.1 2 0 0 2 2 2 0 Ribosomal protein L6e HEAT PF02985.17 CCC70641.1 - 7.5e-41 134.5 16.1 0.0045 16.9 0.0 13.1 12 1 0 12 12 12 11 HEAT repeat HEAT_2 PF13646.1 CCC70641.1 - 2.5e-31 107.7 0.4 2.3e-07 31.0 0.0 8.3 1 1 4 7 7 7 5 HEAT repeats Vac14_Fab1_bd PF12755.2 CCC70641.1 - 7.1e-13 48.7 6.0 0.015 15.6 0.0 8.4 3 3 5 9 9 9 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 CCC70641.1 - 1.8e-05 25.0 15.5 6 7.4 0.0 9.5 8 3 3 11 11 11 2 HEAT-like repeat DNA_alkylation PF08713.6 CCC70641.1 - 0.028 13.9 0.2 1.6 8.1 0.0 3.5 4 1 1 5 5 5 0 DNA alkylation repair enzyme Pkinase PF00069.20 CCC70642.1 - 1.1e-62 211.5 0.0 2e-62 210.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC70642.1 - 3.5e-22 78.7 0.0 6.8e-22 77.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC70642.1 - 1.7e-09 37.0 0.0 4.7e-09 35.6 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCC70642.1 - 0.003 17.3 0.0 0.0057 16.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 CCC70642.1 - 0.012 14.6 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 CCC70642.1 - 0.022 14.1 0.1 0.054 12.8 0.1 1.6 1 0 0 1 1 1 0 RIO1 family PAS_9 PF13426.1 CCC70642.1 - 0.034 14.5 0.0 1.8 8.9 0.0 2.7 2 0 0 2 2 2 0 PAS domain PAS PF00989.19 CCC70642.1 - 0.043 13.6 0.0 2.4 7.9 0.0 3.2 3 0 0 3 3 3 0 PAS fold Ycf4 PF02392.11 CCC70643.1 - 0.017 14.4 1.4 0.044 13.0 0.9 1.6 1 0 0 1 1 1 0 Ycf4 Med15_fungi PF05397.7 CCC70644.1 - 4.2e-39 133.0 2.5 4.2e-39 133.0 1.7 6.2 5 1 1 7 7 7 1 Mediator complex subunit 15 NAD_Gly3P_dh_C PF07479.9 CCC70644.1 - 0.017 14.8 0.2 0.053 13.2 0.1 1.8 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SNF2_N PF00176.18 CCC70646.1 - 7.5e-69 231.7 2.5 1.5e-68 230.7 0.4 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCC70646.1 - 4.9e-16 58.3 0.0 1.2e-14 53.9 0.0 3.2 4 0 0 4 4 4 1 Helicase conserved C-terminal domain CUE PF02845.11 CCC70646.1 - 4.1e-05 22.9 0.1 0.0001 21.6 0.0 1.7 1 0 0 1 1 1 1 CUE domain AAA_22 PF13401.1 CCC70646.1 - 0.0052 16.9 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain PBP1_TM PF14812.1 CCC70646.1 - 0.013 15.7 5.5 0.013 15.7 3.8 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RCC1 PF00415.13 CCC70647.1 - 4.9e-19 68.2 4.5 3.5e-08 33.5 0.0 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCC70647.1 - 3.2e-17 61.6 11.0 1.3e-07 31.0 0.1 6.4 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Exo_endo_phos PF03372.18 CCC70648.1 - 7e-23 81.8 0.2 1e-22 81.2 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 CCC70648.1 - 2.7e-14 52.3 18.0 6.1e-08 32.1 4.4 3.4 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCC70648.1 - 1.1e-08 34.7 11.2 3.1e-08 33.2 4.1 2.9 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 CCC70648.1 - 1.7e-05 24.1 23.7 0.018 15.0 0.1 5.9 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 CCC70648.1 - 0.00057 19.6 12.0 1 9.8 0.1 5.6 4 0 0 4 4 4 2 Leucine rich repeat Nucleoside_tran PF01733.13 CCC70649.1 - 5.6e-70 235.9 12.0 5.6e-70 235.9 8.3 1.5 2 0 0 2 2 2 1 Nucleoside transporter PMT PF02366.13 CCC70650.1 - 1.1e-92 309.9 20.6 1.1e-92 309.9 14.2 2.7 2 1 1 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCC70650.1 - 8.6e-25 87.3 0.3 1.5e-24 86.6 0.2 1.4 1 0 0 1 1 1 1 MIR domain RasGEF PF00617.14 CCC70651.1 - 1.5e-42 145.4 2.4 5.3e-42 143.6 1.7 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 CCC70651.1 - 1.6e-11 44.2 1.5 1.6e-11 44.2 1.0 3.0 3 0 0 3 3 3 1 RasGEF N-terminal motif Rad33 PF08730.5 CCC70652.1 - 0.028 13.9 0.1 0.064 12.7 0.0 1.6 1 0 0 1 1 1 0 Rad33 T4_tail_cap PF11091.3 CCC70654.1 - 0.029 13.1 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 Tail-tube assembly protein E1-E2_ATPase PF00122.15 CCC70655.1 - 1.5e-18 66.6 0.2 2.7e-18 65.8 0.1 1.3 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 CCC70655.1 - 1e-17 64.9 0.1 2.9e-17 63.4 0.1 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC70655.1 - 6.7e-14 52.8 0.4 4.1e-12 46.9 0.3 3.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 CCC70655.1 - 7.1e-11 41.9 0.0 3.1e-10 39.8 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 CCC70655.1 - 0.0009 18.8 1.0 0.017 14.7 0.7 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Saw1 PF11561.3 CCC70656.1 - 4.9e-49 166.6 4.5 5.6e-49 166.4 3.1 1.0 1 0 0 1 1 1 1 Single strand annealing-weakened 1 bPH_5 PF10882.3 CCC70656.1 - 0.096 12.4 0.1 0.23 11.2 0.0 1.7 1 1 0 1 1 1 0 Bacterial PH domain Hph PF13694.1 CCC70657.1 - 2.9e-15 56.8 15.0 2.9e-15 56.8 10.4 4.0 2 1 1 3 3 3 1 Sec63/Sec62 complex-interacting family Fib_alpha PF08702.5 CCC70657.1 - 6.7 6.8 10.8 22 5.1 7.5 1.9 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Myosin_head PF00063.16 CCC70658.1 - 1.5e-250 833.0 15.8 2.3e-250 832.4 11.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 CCC70658.1 - 1.5e-27 95.5 5.6 1.5e-27 95.5 3.9 2.5 2 0 0 2 2 2 1 DIL domain AAA_22 PF13401.1 CCC70658.1 - 0.00081 19.5 1.0 0.019 15.1 0.0 3.4 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 CCC70658.1 - 0.0027 17.9 0.2 0.04 14.1 0.0 3.0 2 0 0 2 2 2 1 ABC transporter IQ PF00612.22 CCC70658.1 - 0.0097 15.4 16.4 2.5 7.9 0.1 6.4 7 0 0 7 7 7 2 IQ calmodulin-binding motif RNA_helicase PF00910.17 CCC70658.1 - 0.012 15.7 0.1 3.9 7.6 0.0 3.1 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 CCC70658.1 - 0.035 14.1 0.2 0.43 10.5 0.0 2.8 2 1 1 3 3 3 0 AAA ATPase domain AAA_19 PF13245.1 CCC70658.1 - 0.055 13.2 0.0 0.43 10.3 0.0 2.4 3 0 0 3 3 3 0 Part of AAA domain vATP-synt_E PF01991.13 CCC70659.1 - 3.3e-57 192.9 19.8 3.9e-57 192.7 13.7 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Phlebovirus_NSM PF07246.6 CCC70659.1 - 0.0025 17.0 7.7 0.004 16.3 5.3 1.3 1 0 0 1 1 1 1 Phlebovirus nonstructural protein NS-M Polysacc_deac_1 PF01522.16 CCC70659.1 - 0.0059 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase EMP24_GP25L PF01105.19 CCC70661.1 - 1e-35 123.1 0.3 1.2e-35 122.8 0.2 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Kisspeptin PF15152.1 CCC70661.1 - 0.085 13.5 0.0 0.21 12.3 0.0 1.7 1 0 0 1 1 1 0 Kisspeptin GHL13 PF14883.1 CCC70661.1 - 0.098 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 13 FUN14 PF04930.10 CCC70662.1 - 0.082 13.1 10.2 0.042 14.1 4.6 2.3 2 1 0 2 2 2 0 FUN14 family Spo7 PF03907.8 CCC70663.1 - 1.7e-81 272.8 4.4 2.2e-81 272.4 3.0 1.1 1 0 0 1 1 1 1 Spo7-like protein DUF2207 PF09972.4 CCC70663.1 - 0.002 16.7 0.0 0.0027 16.3 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF3722 PF12519.3 CCC70664.1 - 1.1e-71 241.0 13.1 1.6e-71 240.6 7.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3722) GCR1_C PF12550.3 CCC70666.1 - 4.2e-23 81.0 0.3 1e-22 79.7 0.2 1.7 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes SR-25 PF10500.4 CCC70666.1 - 0.0016 17.9 5.1 0.0016 17.9 3.5 3.0 3 0 0 3 3 3 1 Nuclear RNA-splicing-associated protein FliJ PF02050.11 CCC70666.1 - 0.0067 16.4 1.8 0.019 15.0 1.2 1.7 1 0 0 1 1 1 1 Flagellar FliJ protein DsrC PF04358.8 CCC70666.1 - 0.027 14.7 0.1 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 DsrC like protein DUF4061 PF13270.1 CCC70666.1 - 0.11 12.6 2.8 0.46 10.6 2.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) DUF159 PF02586.9 CCC70667.1 - 4.6e-58 196.1 0.6 5.6e-58 195.8 0.4 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 TPR_12 PF13424.1 CCC70668.1 - 5.1e-05 23.1 1.9 0.5 10.3 0.0 3.7 3 1 0 3 3 3 2 Tetratricopeptide repeat Cep57_CLD_2 PF14197.1 CCC70668.1 - 0.0039 17.1 0.1 0.0094 15.8 0.1 1.7 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 WD40 PF00400.27 CCC70669.1 - 1.8e-55 182.9 10.6 9.8e-09 34.7 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 CCC70669.1 - 1.7e-05 24.6 0.5 0.0024 17.6 0.1 3.0 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 CCC70669.1 - 2.8e-05 22.4 5.2 0.099 10.7 0.1 3.8 1 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 CCC70669.1 - 0.00038 19.3 0.2 0.9 8.2 0.2 2.9 2 2 1 3 3 3 2 Nup133 N terminal like Spc24 PF08286.6 CCC70670.1 - 6.9e-19 67.6 3.5 6.9e-19 67.6 2.4 2.6 1 1 1 2 2 2 1 Spc24 subunit of Ndc80 LemA PF04011.7 CCC70670.1 - 0.021 13.9 0.4 0.031 13.3 0.3 1.2 1 0 0 1 1 1 0 LemA family GLE1 PF07817.8 CCC70670.1 - 0.033 13.1 1.3 0.047 12.6 0.9 1.3 1 0 0 1 1 1 0 GLE1-like protein APG6 PF04111.7 CCC70670.1 - 0.039 13.0 4.0 0.054 12.5 2.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 GrpE PF01025.14 CCC70670.1 - 0.062 12.8 1.5 0.092 12.2 1.1 1.3 1 0 0 1 1 1 0 GrpE Allexi_40kDa PF05549.6 CCC70670.1 - 0.081 12.2 2.9 0.11 11.7 2.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein End_N_terminal PF12218.3 CCC70670.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase zf-C4H2 PF10146.4 CCC70670.1 - 0.1 12.6 3.5 0.13 12.2 2.5 1.1 1 0 0 1 1 1 0 Zinc finger-containing protein CpXC PF14353.1 CCC70670.1 - 0.12 12.3 0.2 0.21 11.5 0.2 1.4 1 0 0 1 1 1 0 CpXC protein Rabaptin PF03528.10 CCC70670.1 - 0.18 11.7 4.9 0.28 11.1 2.4 2.0 1 1 1 2 2 2 0 Rabaptin TMPIT PF07851.8 CCC70670.1 - 0.2 10.7 2.8 0.25 10.3 1.9 1.1 1 0 0 1 1 1 0 TMPIT-like protein IncA PF04156.9 CCC70670.1 - 0.26 10.8 3.8 0.43 10.1 2.6 1.4 1 0 0 1 1 1 0 IncA protein DUF2935 PF11155.3 CCC70670.1 - 0.27 11.3 2.7 2.2 8.3 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) zf-C3HC4_3 PF13920.1 CCC70671.1 - 4.5e-08 32.6 12.8 9e-08 31.6 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF997 PF06196.7 CCC70671.1 - 0.026 14.0 0.3 0.066 12.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF997) zf-C3HC4_2 PF13923.1 CCC70671.1 - 3.1 7.8 15.8 8.9 6.4 10.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) AICARFT_IMPCHas PF01808.13 CCC70672.1 - 6.1e-118 393.4 0.0 8e-118 393.0 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 CCC70672.1 - 1.3e-23 82.7 0.2 2.9e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 MGS-like domain Pkr1 PF08636.5 CCC70674.1 - 2.3e-33 114.0 10.6 2.7e-33 113.8 7.3 1.1 1 0 0 1 1 1 1 ER protein Pkr1 MIF4G_like PF09088.6 CCC70676.1 - 2.8e-58 196.5 1.9 7.6e-58 195.1 1.3 1.7 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 CCC70676.1 - 2e-49 168.1 1.4 2e-49 168.1 0.9 2.6 2 0 0 2 2 2 1 MIF4G like MIF4G PF02854.14 CCC70676.1 - 5.4e-15 55.3 3.9 5.4e-15 55.3 2.7 2.7 3 1 0 3 3 3 1 MIF4G domain DUF805 PF05656.9 CCC70677.1 - 0.67 9.7 3.2 1.2 9.0 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) OppC_N PF12911.2 CCC70677.1 - 5.4 6.4 6.1 2.6 7.4 0.5 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C MOZ_SAS PF01853.13 CCC70678.1 - 1.1e-61 207.4 1.3 1.5e-61 206.9 0.9 1.2 1 0 0 1 1 1 1 MOZ/SAS family DUF1168 PF06658.7 CCC70678.1 - 0.087 12.3 2.5 0.15 11.6 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) HAD_2 PF13419.1 CCC70680.1 - 2.6e-16 60.3 0.0 3.9e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCC70680.1 - 9.7e-08 31.6 0.0 2.2e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCC70680.1 - 7e-06 26.6 0.0 8.4e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Polysacc_deac_1 PF01522.16 CCC70680.1 - 0.14 11.8 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide deacetylase WD40 PF00400.27 CCC70681.1 - 3.1e-20 71.2 7.9 4e-07 29.6 0.0 5.0 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 CCC70681.1 - 1.7e-18 66.2 0.0 3.8e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF814 PF05670.8 CCC70682.1 - 1.4e-19 69.7 0.0 2.3e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Meiotic_rec114 PF03525.9 CCC70683.1 - 5.1e-13 48.2 4.6 5.1e-13 48.2 3.2 1.8 1 1 1 2 2 2 1 Meiotic recombination protein rec114 CLTH PF10607.4 CCC70685.1 - 1.8e-21 76.3 5.8 1.8e-21 76.3 4.0 2.3 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain RhoGAP PF00620.22 CCC70686.1 - 0.0006 19.4 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RNA_pol_Rpb1_6 PF04992.9 CCC70686.1 - 0.01 15.6 0.2 0.027 14.2 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 6 6PGD PF00393.14 CCC70687.1 - 1.3e-132 441.4 0.0 1.5e-132 441.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 CCC70687.1 - 5.2e-52 175.9 0.0 7.4e-52 175.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 CCC70687.1 - 0.023 15.1 0.0 0.044 14.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_11 PF14833.1 CCC70687.1 - 0.037 14.0 0.0 0.17 11.9 0.0 2.1 3 0 0 3 3 3 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 2-Hacid_dh_C PF02826.14 CCC70687.1 - 0.12 11.5 0.0 0.25 10.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Raptor_N PF14538.1 CCC70689.1 - 1.4e-66 223.1 3.4 1.6e-66 222.8 0.0 2.6 2 0 0 2 2 2 1 Raptor N-terminal CASPase like domain HEAT PF02985.17 CCC70689.1 - 3e-06 26.8 2.0 0.042 13.9 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat BBS2_Mid PF14783.1 CCC70689.1 - 0.00039 20.1 3.3 0.034 13.9 0.1 3.1 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 CCC70689.1 - 0.0006 19.6 3.8 1.6 8.7 0.0 5.8 7 0 0 7 7 7 1 WD domain, G-beta repeat Cpn60_TCP1 PF00118.19 CCC70690.1 - 1.2e-133 446.2 5.9 1.4e-133 446.0 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Vps53_N PF04100.7 CCC70691.1 - 6.5e-83 278.6 17.5 1.4e-82 277.5 12.1 1.6 1 0 0 1 1 1 1 Vps53-like, N-terminal TcdB_N PF12918.2 CCC70691.1 - 0.014 15.4 0.3 0.014 15.4 0.2 3.3 4 0 0 4 4 4 0 TcdB toxin N-terminal helical domain DivIVA PF05103.8 CCC70691.1 - 0.99 9.4 7.1 0.26 11.3 0.3 3.3 3 1 1 4 4 4 0 DivIVA protein PPTA PF01239.17 CCC70692.1 - 2.3e-37 124.8 20.9 4.1e-08 32.2 0.1 6.0 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat ESAG1 PF03238.8 CCC70692.1 - 0.0056 16.0 0.5 0.052 12.8 0.1 2.1 2 0 0 2 2 2 1 ESAG protein Coatomer_b_Cpla PF14806.1 CCC70692.1 - 6.9 6.3 9.6 0.86 9.3 1.9 2.6 2 1 1 3 3 3 0 Coatomer beta subunit appendage platform Cyclin_N PF00134.18 CCC70693.1 - 2.7e-10 39.8 3.7 2.7e-10 39.8 2.6 1.9 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 CCC70693.1 - 0.007 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Methyltransf_11 PF08241.7 CCC70693.1 - 0.14 12.6 0.0 0.36 11.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF3591 PF12157.3 CCC70694.1 - 5.1e-194 644.9 1.5 5.1e-194 644.9 1.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 CCC70694.1 - 2.5e-05 23.8 0.4 5.3e-05 22.8 0.2 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF3135 PF11333.3 CCC70694.1 - 0.029 14.5 0.1 0.082 13.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) zf-CCHC PF00098.18 CCC70694.1 - 0.24 11.3 0.3 0.58 10.1 0.2 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF1840 PF08895.6 CCC70694.1 - 6.3 6.8 8.4 6.6 6.8 2.1 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF1840) Peptidase_S10 PF00450.17 CCC70696.1 - 9.5e-128 426.8 0.2 1.2e-127 426.5 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 CCC70696.1 - 3.2e-19 69.1 0.2 5.4e-19 68.4 0.1 1.4 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Aminotran_1_2 PF00155.16 CCC70697.1 - 9.4e-63 212.3 0.0 1.1e-62 212.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2406 PF10295.4 CCC70698.1 - 3.3e-27 94.8 1.1 4.2e-27 94.4 0.2 1.6 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) Dynamitin PF04912.9 CCC70699.1 - 4.5e-07 29.0 27.4 4.5e-07 29.0 19.0 2.4 1 1 1 2 2 2 1 Dynamitin Reovirus_cap PF00979.12 CCC70699.1 - 0.099 11.5 0.1 0.18 10.7 0.1 1.3 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 Sulfatase_C PF14707.1 CCC70699.1 - 0.45 10.8 2.6 0.64 10.3 0.2 2.4 2 1 0 2 2 2 0 C-terminal region of aryl-sulfatase Reo_sigmaC PF04582.7 CCC70699.1 - 0.57 9.3 4.6 7 5.7 0.2 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF2443 PF10398.4 CCC70699.1 - 0.63 9.8 6.9 0.089 12.6 0.6 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2443) V-ATPase_G PF03179.10 CCC70699.1 - 1.7 9.0 14.7 1.5 9.1 0.4 3.8 3 1 0 3 3 3 0 Vacuolar (H+)-ATPase G subunit DUF1664 PF07889.7 CCC70699.1 - 2.8 7.7 20.0 0.22 11.3 2.5 4.4 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) PspB PF06667.7 CCC70699.1 - 4.8 7.1 8.4 8.1 6.4 0.1 3.7 3 1 1 4 4 4 0 Phage shock protein B Amidase PF01425.16 CCC70700.1 - 3.8e-106 355.6 0.0 4.5e-106 355.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Got1 PF04178.7 CCC70701.1 - 2.4e-17 63.1 7.0 2.7e-17 62.9 4.9 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 CCC70701.1 - 0.015 14.2 5.7 0.023 13.6 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF973) PEMT PF04191.8 CCC70701.1 - 0.055 13.5 2.3 0.29 11.2 0.7 2.1 2 0 0 2 2 2 0 Phospholipid methyltransferase COX4_pro_2 PF07835.7 CCC70701.1 - 0.069 13.1 0.1 0.23 11.4 0.1 1.9 1 1 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV YrhK PF14145.1 CCC70701.1 - 0.17 11.5 3.3 0.76 9.4 2.1 2.1 1 1 0 1 1 1 0 YrhK-like protein DUF872 PF05915.7 CCC70701.1 - 0.55 10.0 2.9 0.42 10.4 0.8 1.7 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Prp19 PF08606.6 CCC70702.1 - 1.4e-29 101.6 1.2 2.1e-29 101.0 0.8 1.3 1 0 0 1 1 1 1 Prp19/Pso4-like zf-Nse PF11789.3 CCC70702.1 - 0.00043 19.7 0.0 0.001 18.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 CCC70702.1 - 0.0015 18.4 0.0 0.0042 17.0 0.0 1.8 1 0 0 1 1 1 1 U-box domain DUF1635 PF07795.6 CCC70702.1 - 0.0033 16.8 1.3 0.0078 15.6 0.9 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) NUDIX_2 PF13869.1 CCC70702.1 - 0.11 11.8 0.3 0.16 11.2 0.2 1.4 1 1 0 1 1 1 0 Nucleotide hydrolase DUF972 PF06156.8 CCC70702.1 - 2.5 8.5 4.7 8.9 6.7 2.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) Pkinase PF00069.20 CCC70703.1 - 6.4e-50 169.7 0.7 1e-48 165.7 0.5 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC70703.1 - 1e-20 73.9 0.1 5.6e-18 64.9 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCC70703.1 - 0.0036 16.2 2.5 0.14 11.1 0.0 2.6 3 0 0 3 3 3 2 Kinase-like Paramyxo_C PF01692.13 CCC70703.1 - 1.4 8.4 8.6 1.2 8.6 3.5 2.4 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c DEAD PF00270.24 CCC70704.1 - 6.1e-44 149.4 0.7 2e-43 147.8 0.0 2.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC70704.1 - 1.9e-21 75.6 0.0 5.2e-21 74.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCC70704.1 - 8.1e-21 73.3 0.4 1.6e-20 72.4 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CCC70704.1 - 0.009 15.8 0.0 0.031 14.1 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 CCC70704.1 - 0.011 15.0 0.0 0.035 13.3 0.0 1.7 1 1 0 1 1 1 0 SecA DEAD-like domain AAA_22 PF13401.1 CCC70704.1 - 0.032 14.3 1.2 0.18 11.9 0.6 2.4 2 1 0 2 2 2 0 AAA domain tRNA-synt_1g PF09334.6 CCC70705.1 - 3.8e-146 486.7 0.0 5.3e-146 486.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) MetRS-N PF09635.5 CCC70705.1 - 1.2e-29 103.1 5.2 4.3e-29 101.3 3.6 2.0 1 0 0 1 1 1 1 MetRS-N binding domain tRNA-synt_1 PF00133.17 CCC70705.1 - 9.8e-10 37.0 0.4 0.00031 18.8 0.0 2.9 1 1 1 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 CCC70705.1 - 0.0096 15.0 0.0 0.048 12.7 0.0 2.1 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 CCC70705.1 - 0.028 14.2 0.5 0.11 12.2 0.0 2.2 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA Aminotran_4 PF01063.14 CCC70706.1 - 2.1e-22 79.7 0.0 2.9e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV HEAT_2 PF13646.1 CCC70707.1 - 5.6e-16 58.6 0.1 0.014 15.6 0.0 7.9 4 2 4 8 8 8 4 HEAT repeats HEAT PF02985.17 CCC70707.1 - 3.4e-13 48.4 7.9 1.3 9.2 0.1 10.5 11 0 0 11 11 11 4 HEAT repeat HEAT_EZ PF13513.1 CCC70707.1 - 4e-12 46.2 0.0 1.4 9.5 0.0 8.8 8 1 2 10 10 10 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 CCC70707.1 - 4.9e-06 26.8 1.8 0.055 13.8 0.0 5.9 7 1 0 7 7 7 1 Vacuolar 14 Fab1-binding region Gpi16 PF04113.9 CCC70708.1 - 3.9e-189 629.3 0.0 4.8e-189 629.0 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Elong_Iki1 PF10483.4 CCC70709.1 - 1.2e-84 284.0 9.7 1.3e-84 283.8 6.7 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 NACHT PF05729.7 CCC70709.1 - 0.035 13.7 0.1 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Utp13 PF08625.6 CCC70709.1 - 0.22 11.1 2.2 0.32 10.6 0.2 2.1 2 1 1 3 3 3 0 Utp13 specific WD40 associated domain PUF PF00806.14 CCC70710.1 - 9.7e-35 116.1 9.3 4.9e-06 25.7 0.0 9.5 9 0 0 9 9 9 8 Pumilio-family RNA binding repeat DUF3294 PF07957.6 CCC70711.1 - 3.9e-73 245.5 3.7 4.3e-73 245.4 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3294) DUF2959 PF11172.3 CCC70711.1 - 0.026 14.2 2.1 0.046 13.4 0.4 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2959) Tricorn_C1 PF14684.1 CCC70711.1 - 0.074 12.9 0.2 22 5.0 0.0 3.1 3 0 0 3 3 3 0 Tricorn protease C1 domain Rotavirus_VP7 PF05868.6 CCC70711.1 - 0.096 11.8 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Rotavirus major outer capsid protein VP7 CcdA PF07362.7 CCC70711.1 - 0.23 11.3 1.9 13 5.7 0.1 3.0 3 0 0 3 3 3 0 Post-segregation antitoxin CcdA BRE1 PF08647.6 CCC70711.1 - 0.86 9.6 5.0 13 5.8 0.4 2.8 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase LTV PF04180.9 CCC70712.1 - 4.3e-124 415.2 35.0 5e-124 415.0 24.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein DUF3804 PF12707.2 CCC70712.1 - 0.05 13.1 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3804) RNA_pol_Rbc25 PF08292.7 CCC70713.1 - 1e-43 148.4 3.7 2.6e-43 147.1 2.6 1.6 1 1 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 CCC70713.1 - 3.5e-21 75.1 0.0 5.1e-21 74.5 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 CCC70713.1 - 0.015 15.3 2.1 0.05 13.7 0.0 2.5 1 1 1 2 2 2 0 S1 RNA binding domain AAA PF00004.24 CCC70714.1 - 1.4e-40 138.5 0.0 2.6e-40 137.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCC70714.1 - 4.9e-06 26.7 0.0 0.00096 19.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 CCC70714.1 - 2.4e-05 24.0 0.0 0.00011 21.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 CCC70714.1 - 0.00013 21.8 0.0 0.00032 20.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCC70714.1 - 0.00013 21.9 0.0 0.0013 18.7 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 CCC70714.1 - 0.0011 19.7 0.7 0.0028 18.4 0.1 2.2 2 1 0 2 2 1 1 AAA domain DUF815 PF05673.8 CCC70714.1 - 0.0011 17.8 0.0 0.0021 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.7 CCC70714.1 - 0.0032 16.5 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 CCC70714.1 - 0.0066 16.1 0.2 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_28 PF13521.1 CCC70714.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 CCC70714.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 CCC70714.1 - 0.014 15.6 0.0 0.063 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 CCC70714.1 - 0.016 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 CCC70714.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 CCC70714.1 - 0.024 14.7 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 CCC70714.1 - 0.028 14.4 0.0 0.065 13.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 CCC70714.1 - 0.032 13.6 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 CCC70714.1 - 0.035 13.6 0.0 0.066 12.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.16 CCC70714.1 - 0.042 12.9 0.0 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 CCC70714.1 - 0.047 12.4 0.0 0.084 11.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_24 PF13479.1 CCC70714.1 - 0.082 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 CCC70714.1 - 0.13 11.8 1.8 4.7 6.8 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase SF-assemblin PF06705.6 CCC70714.1 - 0.27 10.3 3.4 0.21 10.6 0.2 2.1 1 1 1 2 2 2 0 SF-assemblin/beta giardin Aa_trans PF01490.13 CCC70715.1 - 2.2e-96 322.8 34.6 2.7e-96 322.5 24.0 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 CCC70715.1 - 0.19 10.2 39.5 0.081 11.4 19.9 2.2 1 1 1 2 2 2 0 Amino acid permease FAD_binding_2 PF00890.19 CCC70716.1 - 5.7e-122 407.5 3.2 7e-122 407.2 2.2 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 CCC70716.1 - 7.3e-49 164.9 0.4 1.1e-48 164.3 0.2 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.12 CCC70716.1 - 1.8e-05 23.9 0.1 0.003 16.6 0.0 2.5 3 0 0 3 3 3 2 Thi4 family Pyr_redox_2 PF07992.9 CCC70716.1 - 0.00013 21.8 0.7 0.0026 17.6 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 CCC70716.1 - 0.00027 19.9 0.5 0.013 14.4 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 CCC70716.1 - 0.00061 18.7 1.9 0.029 13.2 1.2 2.4 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 CCC70716.1 - 0.013 14.5 0.7 0.047 12.7 0.1 2.0 2 0 0 2 2 2 0 FAD binding domain DBR1 PF05011.8 CCC70717.1 - 1.2e-11 44.6 0.8 3.2e-11 43.3 0.1 1.9 1 1 1 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 CCC70717.1 - 3.1e-09 36.5 1.9 7.7e-09 35.2 1.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCC70717.1 - 0.058 13.2 0.0 0.098 12.4 0.0 1.5 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain FAD_binding_6 PF00970.19 CCC70718.1 - 2.2e-24 85.4 0.0 4.5e-24 84.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 CCC70718.1 - 4.3e-24 85.1 0.0 6.6e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 CCC70718.1 - 0.00028 20.8 0.0 0.0057 16.5 0.0 2.3 2 0 0 2 2 2 1 Ferric reductase NAD binding domain DUF4465 PF14717.1 CCC70718.1 - 0.0034 17.8 0.0 0.0059 17.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4465) FAD_binding_9 PF08021.6 CCC70718.1 - 0.065 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain DUF3242 PF11586.3 CCC70718.1 - 0.097 12.2 0.2 0.2 11.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Carb_kinase PF01256.12 CCC70719.1 - 2.5e-68 229.9 0.0 2.8e-67 226.5 0.0 1.9 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.7 CCC70719.1 - 3.5e-05 23.1 0.0 4.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase HK PF02110.10 CCC70719.1 - 0.02 14.0 0.0 0.034 13.3 0.0 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family DUF1792 PF08759.6 CCC70719.1 - 0.17 11.4 0.0 0.57 9.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1792) PA14 PF07691.7 CCC70720.1 - 7.5e-21 74.3 3.4 8.1e-10 38.5 0.0 2.9 3 0 0 3 3 3 2 PA14 domain PA14_2 PF10528.4 CCC70720.1 - 7.5e-16 58.0 23.4 1.6e-08 34.4 1.4 4.2 3 0 0 3 3 3 2 GLEYA domain Flocculin PF00624.13 CCC70720.1 - 0.00013 21.6 27.7 0.00069 19.3 5.3 12.3 13 1 1 14 14 14 2 Flocculin repeat His_Phos_1 PF00300.17 CCC70721.1 - 1.7e-43 148.4 0.0 2.2e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SRPRB PF09439.5 CCC70722.1 - 8.1e-58 194.6 1.5 1.1e-57 194.2 1.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 CCC70722.1 - 1e-12 47.6 0.1 1.4e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 CCC70722.1 - 1.5e-09 37.8 0.2 3.7e-09 36.5 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 CCC70722.1 - 5.8e-07 28.8 0.3 7e-07 28.6 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 CCC70722.1 - 6.5e-06 25.5 0.1 1.2e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 CCC70722.1 - 0.00013 21.4 0.1 0.0029 17.0 0.1 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CCC70722.1 - 0.00017 22.0 0.1 0.00045 20.6 0.0 1.8 1 1 1 2 2 2 1 Miro-like protein ATP_bind_1 PF03029.12 CCC70722.1 - 0.00017 21.1 0.5 0.00027 20.5 0.4 1.4 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 CCC70722.1 - 0.0065 15.9 0.0 0.018 14.5 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 CCC70722.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 CCC70722.1 - 0.031 13.9 0.3 0.11 12.1 0.2 2.0 1 1 0 1 1 1 0 Archaeal ATPase SRP54 PF00448.17 CCC70722.1 - 0.085 12.2 0.1 0.19 11.1 0.0 1.6 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 CCC70722.1 - 0.11 12.8 5.3 1 9.6 3.7 2.1 1 1 0 1 1 1 0 AAA domain DUF4611 PF15387.1 CCC70722.1 - 0.44 10.7 3.1 5.1 7.3 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Rsm22 PF09243.5 CCC70723.1 - 6.2e-30 104.1 2.0 1.9e-10 40.2 0.0 4.4 4 1 0 4 4 4 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_11 PF08241.7 CCC70723.1 - 0.0065 16.9 0.1 3.5 8.1 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC70723.1 - 0.007 16.1 0.0 0.015 15.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC70723.1 - 0.0078 16.7 0.4 0.2 12.2 0.1 3.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCC70723.1 - 0.071 13.5 3.3 0.15 12.5 0.0 2.9 3 0 0 3 3 3 0 Methyltransferase domain NodS PF05401.6 CCC70723.1 - 0.1 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) Ribosomal_S27e PF01667.12 CCC70724.1 - 1e-29 101.7 3.5 1.4e-29 101.3 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 CCC70724.1 - 8.1e-05 22.4 0.6 0.0001 22.1 0.4 1.1 1 0 0 1 1 1 1 IBR domain TF_Zn_Ribbon PF08271.7 CCC70724.1 - 0.051 12.9 3.8 0.074 12.3 2.6 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding zinc_ribbon_5 PF13719.1 CCC70724.1 - 0.13 11.8 1.3 6.2 6.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 CCC70724.1 - 0.14 11.8 1.3 6.3 6.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Pkinase PF00069.20 CCC70725.1 - 1.5e-55 188.1 0.1 2e-55 187.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC70725.1 - 1.4e-26 93.1 0.0 2.4e-26 92.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase KH_5 PF13184.1 CCC70725.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.5 1 0 0 1 1 1 0 NusA-like KH domain Kinase-like PF14531.1 CCC70725.1 - 0.11 11.3 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Calcipressin PF04847.7 CCC70726.1 - 1.6e-25 89.7 0.2 2e-25 89.4 0.1 1.1 1 0 0 1 1 1 1 Calcipressin Peptidase_M1 PF01433.15 CCC70727.1 - 3.8e-145 483.8 1.7 3.8e-145 483.8 1.2 1.8 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 CCC70727.1 - 3.9e-88 295.8 0.3 9.8e-88 294.5 0.1 1.8 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 CCC70727.1 - 1.3e-20 73.7 0.4 3e-20 72.5 0.3 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily HEAT_2 PF13646.1 CCC70727.1 - 0.037 14.2 0.1 2.3 8.5 0.0 2.5 1 1 1 2 2 2 0 HEAT repeats RNase_H2-Ydr279 PF09468.5 CCC70728.1 - 2.5e-51 174.6 8.7 3e-51 174.4 6.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) adh_short PF00106.20 CCC70729.1 - 1.1e-07 31.8 0.0 2.2e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 CCC70729.1 - 1.5e-05 25.1 0.0 2.8e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 CCC70729.1 - 0.00025 20.7 0.0 0.00048 19.8 0.0 1.5 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 CCC70729.1 - 0.00035 19.7 0.0 0.00055 19.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.16 CCC70729.1 - 0.0022 17.4 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 CCC70729.1 - 0.012 14.5 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 CCC70729.1 - 0.014 14.6 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family F420_oxidored PF03807.12 CCC70729.1 - 0.058 13.8 0.0 0.16 12.3 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Oxidored_nitro PF00148.14 CCC70729.1 - 0.12 11.0 0.0 0.13 10.8 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase adh_short_C2 PF13561.1 CCC70729.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase FAD_binding_1 PF00667.15 CCC70730.1 - 6.6e-65 218.6 0.0 9.9e-65 218.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCC70730.1 - 1.2e-29 103.1 0.7 2.1e-29 102.3 0.5 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCC70730.1 - 2.6e-19 69.8 0.0 6.5e-19 68.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain MAGE PF01454.14 CCC70731.1 - 5.6e-34 117.2 1.6 7e-34 116.8 1.1 1.1 1 0 0 1 1 1 1 MAGE family Inositol_P PF00459.20 CCC70732.1 - 3.7e-72 242.8 0.0 4.1e-72 242.7 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF836 PF05768.9 CCC70733.1 - 2.8e-18 65.9 0.7 3.4e-18 65.6 0.5 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_2 PF13098.1 CCC70733.1 - 0.00032 20.8 0.1 0.00038 20.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Glutaredoxin PF00462.19 CCC70733.1 - 0.00067 19.6 0.1 0.0019 18.1 0.1 1.9 1 1 0 1 1 1 1 Glutaredoxin Thioredoxin_4 PF13462.1 CCC70733.1 - 0.074 13.0 0.1 0.47 10.4 0.0 1.8 1 1 1 2 2 2 0 Thioredoxin RTP PF02334.11 CCC70733.1 - 0.081 12.8 0.3 0.099 12.6 0.2 1.2 1 0 0 1 1 1 0 Replication terminator protein RseA_N PF03872.8 CCC70733.1 - 0.082 13.2 0.6 0.12 12.7 0.4 1.2 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain GerA PF03323.8 CCC70733.1 - 0.14 10.2 0.0 0.16 10.0 0.0 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein Reo_sigmaC PF04582.7 CCC70734.1 - 0.0037 16.5 0.5 0.0037 16.5 0.4 4.5 1 1 2 5 5 5 2 Reovirus sigma C capsid protein PAP2 PF01569.16 CCC70735.1 - 6.3e-22 77.6 2.3 6.3e-22 77.6 1.6 1.6 2 0 0 2 2 2 1 PAP2 superfamily KdpA PF03814.10 CCC70735.1 - 0.016 13.2 0.1 0.023 12.7 0.0 1.2 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit DUF4064 PF13273.1 CCC70735.1 - 0.027 14.5 0.9 0.054 13.5 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) RELT PF12606.3 CCC70735.1 - 0.32 10.1 1.7 0.59 9.3 0.0 2.3 2 0 0 2 2 2 0 Tumour necrosis factor receptor superfamily member 19 RseC_MucC PF04246.7 CCC70735.1 - 3.5 7.2 5.1 3.9 7.0 0.8 2.3 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC HGTP_anticodon2 PF12745.2 CCC70736.1 - 1.1e-95 319.9 2.7 1.1e-95 319.9 1.9 3.2 4 0 0 4 4 4 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 CCC70736.1 - 6.7e-67 225.3 0.6 6.9e-44 149.9 0.1 4.0 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CCC70736.1 - 1.4e-35 122.6 0.1 1.7e-22 79.7 0.0 3.5 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 CCC70736.1 - 1.8e-17 63.2 0.8 1.8e-17 63.2 0.6 2.5 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.1 CCC70736.1 - 5.1e-14 52.0 0.0 1.7e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 Histidyl-tRNA synthetase Kinase-like PF14531.1 CCC70736.1 - 8.6e-05 21.6 0.0 0.12 11.3 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 CCC70736.1 - 0.045 13.4 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family CTD_bind PF04818.8 CCC70737.1 - 6.6e-20 71.1 0.2 5.2e-19 68.2 0.0 2.5 3 0 0 3 3 3 1 RNA polymerase II-binding domain. CTK3 PF12243.3 CCC70737.1 - 0.0015 18.2 0.2 0.0038 16.8 0.0 1.8 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 Carbpep_Y_N PF05388.6 CCC70737.1 - 0.037 14.1 0.1 0.25 11.4 0.0 2.4 2 1 0 2 2 2 0 Carboxypeptidase Y pro-peptide PA14 PF07691.7 CCC70738.1 - 2e-34 118.3 1.7 1e-11 44.6 0.0 3.8 3 0 0 3 3 3 3 PA14 domain PA14_2 PF10528.4 CCC70738.1 - 2e-24 85.7 30.5 2.1e-09 37.3 1.4 4.5 4 0 0 4 4 4 3 GLEYA domain Flocculin PF00624.13 CCC70738.1 - 0.00058 19.6 42.2 0.00066 19.4 13.8 13.5 14 1 0 14 14 14 2 Flocculin repeat PA14_2 PF10528.4 CCC70739.1 - 2.2e-13 50.1 7.2 3.5e-08 33.3 2.2 3.3 2 0 0 2 2 2 2 GLEYA domain PA14 PF07691.7 CCC70739.1 - 1e-11 44.6 0.1 1.2e-08 34.7 0.0 2.6 2 0 0 2 2 2 2 PA14 domain Flocculin PF00624.13 CCC70739.1 - 2.3e-05 24.1 24.1 0.00053 19.7 5.3 8.8 10 0 0 10 10 10 3 Flocculin repeat Pyridoxal_deC PF00282.14 CCC70740.1 - 2.4e-21 75.5 0.0 2.7e-20 72.1 0.0 2.1 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain DegT_DnrJ_EryC1 PF01041.12 CCC70740.1 - 4.3e-06 26.0 0.0 6.7e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 CCC70740.1 - 6.8e-06 25.0 0.0 0.002 16.9 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V RNB PF00773.14 CCC70741.1 - 4e-56 190.6 2.2 4e-56 190.6 1.5 2.5 2 0 0 2 2 2 1 RNB domain OB_RNB PF08206.6 CCC70741.1 - 0.00042 19.7 0.1 0.39 10.2 0.0 2.9 3 0 0 3 3 3 2 Ribonuclease B OB domain zf-HIT PF04438.11 CCC70742.1 - 1.3e-09 37.5 10.8 2.4e-09 36.6 7.5 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-H2C2_2 PF13465.1 CCC70742.1 - 0.7 10.2 9.8 0.88 9.9 5.3 2.3 2 1 0 2 2 2 0 Zinc-finger double domain SRX PF09201.5 CCC70743.1 - 1.6e-51 173.8 2.7 3.6e-51 172.7 1.9 1.6 1 0 0 1 1 1 1 SRX SRP54 PF00448.17 CCC70743.1 - 6.2e-48 162.8 0.2 1e-45 155.5 0.1 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 CCC70743.1 - 2.3e-06 27.1 0.0 6.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 CCC70743.1 - 2.8e-06 27.3 0.3 8e-06 25.8 0.2 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 CCC70743.1 - 9.6e-05 21.2 0.1 0.00032 19.5 0.0 2.0 2 1 0 2 2 2 1 ArgK protein ArsA_ATPase PF02374.10 CCC70743.1 - 0.0019 17.3 0.0 0.2 10.6 0.0 2.7 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.13 CCC70743.1 - 0.0043 16.2 0.1 0.012 14.8 0.0 1.7 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_22 PF13401.1 CCC70743.1 - 0.0062 16.6 0.0 0.044 13.9 0.0 2.5 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 CCC70743.1 - 0.0071 16.0 0.0 0.021 14.5 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 CCC70743.1 - 0.012 15.4 0.0 0.42 10.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 CCC70743.1 - 0.045 13.7 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 CCC70743.1 - 5.7 6.6 9.3 1.2 8.9 0.2 3.4 4 0 0 4 4 4 0 Domain of unknown function DUF87 DEAD PF00270.24 CCC70744.1 - 2.1e-22 79.3 0.0 5.6e-22 78.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1998 PF09369.5 CCC70744.1 - 2e-14 53.8 0.1 5.4e-14 52.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 CCC70744.1 - 2.3e-12 46.5 0.0 7.7e-12 44.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CDT1 PF08839.6 CCC70744.1 - 1.6e-06 28.1 0.8 5.6e-06 26.3 0.5 2.0 1 0 0 1 1 1 1 DNA replication factor CDT1 like PA14 PF07691.7 CCC70746.1 - 3.3e-21 75.4 9.8 1.9e-11 43.7 0.1 4.1 4 0 0 4 4 4 2 PA14 domain PA14_2 PF10528.4 CCC70746.1 - 3.7e-21 75.1 11.3 4.5e-12 45.9 3.6 3.6 2 0 0 2 2 2 2 GLEYA domain OSCP PF00213.13 CCC70747.1 - 3.2e-36 124.7 3.8 3.7e-36 124.5 2.6 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Mhr1 PF12829.2 CCC70748.1 - 1.3e-26 92.2 2.0 2.6e-26 91.2 1.4 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination DUF3105 PF11303.3 CCC70748.1 - 0.0013 18.5 0.0 0.058 13.2 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3105) HDA2-3 PF11496.3 CCC70749.1 - 3.5e-67 226.3 12.8 3.5e-67 226.3 8.9 2.7 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 AATF-Che1 PF13339.1 CCC70750.1 - 1e-29 103.3 4.2 1e-29 103.3 2.9 3.7 3 1 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 CCC70750.1 - 2.3e-27 94.9 5.0 5.3e-27 93.7 0.0 3.4 3 0 0 3 3 3 1 Apoptosis-antagonizing transcription factor, C-terminal AA_kinase PF00696.23 CCC70751.1 - 1.6e-35 122.7 0.6 2.6e-35 122.1 0.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 CCC70751.1 - 9.2e-20 70.1 0.0 1.9e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 PUA domain DUF4224 PF13986.1 CCC70751.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) CPSF_A PF03178.10 CCC70752.1 - 1.3e-83 280.7 0.8 1.4e-81 274.0 0.0 3.3 3 0 0 3 3 3 2 CPSF A subunit region PIG-F PF06699.6 CCC70753.1 - 9.1e-43 146.4 21.3 5.2e-42 143.9 14.7 1.9 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F TauE PF01925.14 CCC70753.1 - 1 8.7 9.3 7 6.0 6.4 2.1 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE Zn_clus PF00172.13 CCC70754.1 - 1.9e-07 30.8 8.1 3.6e-07 29.9 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_isomerase PF00160.16 CCC70755.1 - 5.8e-30 104.5 0.1 7.2e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HIT PF01230.18 CCC70756.1 - 1.7e-08 34.9 0.2 5.5e-08 33.2 0.1 1.7 2 0 0 2 2 2 1 HIT domain CM1 PF03026.10 CCC70757.1 - 0.046 12.8 0.0 0.069 12.2 0.0 1.2 1 0 0 1 1 1 0 Influenza C virus M1 protein LRR_5 PF13306.1 CCC70758.1 - 0.014 15.1 1.4 0.22 11.1 0.0 3.3 2 1 1 3 3 3 0 Leucine rich repeats (6 copies) LRR_8 PF13855.1 CCC70758.1 - 8 6.3 8.6 4.6 7.0 0.3 4.3 5 1 0 5 5 5 0 Leucine rich repeat PMT PF02366.13 CCC70759.1 - 2.8e-22 79.2 20.3 6.9e-22 77.9 14.1 1.7 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCC70759.1 - 4.3e-06 26.3 0.0 3.5e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 MIR domain DUF569 PF04601.8 CCC70759.1 - 0.11 11.8 0.0 0.31 10.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF569) Med21 PF11221.3 CCC70760.1 - 5.8e-50 169.0 2.9 6.8e-50 168.7 2.0 1.1 1 0 0 1 1 1 1 Subunit 21 of Mediator complex DUF2200 PF09966.4 CCC70760.1 - 0.00039 20.2 0.1 0.069 13.0 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2200) Med9 PF07544.8 CCC70760.1 - 0.0018 17.9 2.8 0.0076 15.9 1.9 2.0 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 TMCO5 PF14992.1 CCC70760.1 - 0.02 14.0 2.5 0.022 13.8 1.7 1.2 1 0 0 1 1 1 0 TMCO5 family DUF948 PF06103.6 CCC70760.1 - 0.32 10.8 4.3 10 6.0 1.0 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FYVE PF01363.16 CCC70761.1 - 2.6e-18 65.6 11.5 2.6e-18 65.6 8.0 3.0 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 CCC70761.1 - 1.6e-10 40.6 3.8 1.6e-10 40.6 2.6 3.9 2 1 1 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 CCC70761.1 - 0.00035 20.2 1.7 0.00035 20.2 1.2 4.1 5 0 0 5 5 5 1 RING-type zinc-finger zf-C3HC4 PF00097.20 CCC70761.1 - 0.00085 18.9 3.4 0.00085 18.9 2.4 4.9 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC70761.1 - 0.0056 16.6 5.2 0.0056 16.6 3.6 4.5 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Brix PF04427.13 CCC70762.1 - 5.9e-59 198.9 3.6 9.3e-59 198.2 2.5 1.3 1 0 0 1 1 1 1 Brix domain DEAD PF00270.24 CCC70763.1 - 2.8e-47 160.3 0.0 6.5e-47 159.1 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC70763.1 - 9e-27 92.7 0.0 3.3e-26 90.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC70763.1 - 5.5e-06 26.3 0.3 8.5e-05 22.4 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit RP-C_C PF11800.3 CCC70763.1 - 0.085 12.5 7.3 0.16 11.6 5.1 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Vfa1 PF08432.5 CCC70763.1 - 3.9 7.4 14.0 6.8 6.6 9.7 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 PBD PF00786.23 CCC70764.1 - 0.00052 20.3 0.0 0.0023 18.2 0.0 2.3 1 0 0 1 1 1 1 P21-Rho-binding domain Ins_P5_2-kin PF06090.7 CCC70766.1 - 1.4e-37 129.3 2.4 1.8e-37 129.0 1.6 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Methyltransf_23 PF13489.1 CCC70767.1 - 1.4e-17 63.9 0.0 2.2e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCC70767.1 - 1e-13 50.9 1.4 1.1e-09 37.7 0.1 2.5 2 1 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 CCC70767.1 - 2.1e-13 50.5 0.1 4.9e-12 46.1 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC70767.1 - 4.1e-10 39.4 0.1 1e-09 38.1 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC70767.1 - 3.8e-09 37.0 0.0 9e-08 32.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCC70767.1 - 9.4e-09 35.6 0.0 1.7e-07 31.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC70767.1 - 2.1e-07 31.2 0.0 4.9e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 CCC70767.1 - 0.0092 15.1 0.1 0.22 10.6 0.0 2.4 1 1 1 2 2 2 1 Tellurite resistance protein TehB MttA_Hcf106 PF02416.11 CCC70767.1 - 0.086 11.9 0.1 0.19 10.8 0.0 1.6 1 0 0 1 1 1 0 mttA/Hcf106 family Cyclin PF08613.6 CCC70768.1 - 2.9e-09 37.5 0.2 4.4e-09 36.9 0.2 1.4 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCC70768.1 - 1.7e-07 30.8 0.3 6.8e-07 28.8 0.2 1.9 1 1 0 1 1 1 1 Cyclin, N-terminal domain CENP-O PF09496.5 CCC70769.1 - 1.4e-11 44.4 1.2 2.3e-11 43.7 0.1 1.9 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component DivIC PF04977.10 CCC70769.1 - 0.019 14.4 0.7 0.019 14.4 0.5 2.9 3 0 0 3 3 3 0 Septum formation initiator Syntaxin_2 PF14523.1 CCC70769.1 - 0.021 14.8 5.1 0.14 12.2 3.9 2.0 2 0 0 2 2 2 0 Syntaxin-like protein HeLo PF14479.1 CCC70769.1 - 0.037 13.7 3.7 0.072 12.8 2.4 1.6 1 1 0 1 1 1 0 Prion-inhibition and propagation FlxA PF14282.1 CCC70769.1 - 1.8 8.5 9.9 1.6 8.6 4.6 2.2 1 1 1 2 2 2 0 FlxA-like protein U1snRNP70_N PF12220.3 CCC70769.1 - 2.9 8.2 8.0 0.71 10.2 2.9 1.9 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Scs3p PF10261.4 CCC70770.1 - 4.1e-37 127.5 17.5 2.2e-36 125.1 12.1 2.1 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM PAP2 PF01569.16 CCC70770.1 - 0.12 12.1 4.8 0.31 10.7 2.8 2.1 1 1 1 2 2 2 0 PAP2 superfamily Caveolin PF01146.12 CCC70770.1 - 0.58 9.7 4.3 0.27 10.7 0.4 2.2 2 1 0 2 2 2 0 Caveolin Ubiq-assoc PF09145.5 CCC70771.1 - 5.8e-21 74.0 2.5 8.9e-21 73.4 0.8 2.1 2 0 0 2 2 2 1 Ubiquitin-associated TPR_11 PF13414.1 CCC70771.1 - 2.4e-06 27.0 0.5 3e-05 23.5 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 CCC70771.1 - 1.1e-05 25.2 0.0 0.0001 22.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat DnaJ PF00226.26 CCC70771.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain TPR_1 PF00515.23 CCC70771.1 - 0.016 14.7 0.6 6.8 6.4 0.0 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 CCC70771.1 - 0.028 14.3 0.1 2.6 8.1 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DASH_Dad4 PF08650.5 CCC70772.1 - 7.1e-36 121.9 8.8 7.7e-36 121.8 6.1 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DUF3251 PF11622.3 CCC70772.1 - 0.019 14.3 0.8 0.021 14.2 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) Nsp1_C PF05064.8 CCC70772.1 - 0.021 14.4 1.9 0.025 14.2 1.3 1.1 1 0 0 1 1 1 0 Nsp1-like C-terminal region NPV_P10 PF05531.7 CCC70772.1 - 0.022 14.9 0.6 0.027 14.7 0.4 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.3 CCC70772.1 - 0.03 14.0 0.8 0.031 13.9 0.6 1.1 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding FAM117 PF15388.1 CCC70772.1 - 0.035 13.3 0.9 0.037 13.2 0.6 1.1 1 0 0 1 1 1 0 Protein Family FAM117 DUF2335 PF10097.4 CCC70772.1 - 0.039 13.5 0.1 0.056 13.0 0.0 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2335) Snapin_Pallidin PF14712.1 CCC70772.1 - 0.067 13.5 0.8 0.074 13.3 0.5 1.2 1 0 0 1 1 1 0 Snapin/Pallidin Tropomyosin PF00261.15 CCC70772.1 - 0.082 11.9 0.5 0.088 11.8 0.3 1.1 1 0 0 1 1 1 0 Tropomyosin UPF0122 PF04297.9 CCC70772.1 - 0.099 12.6 0.9 0.12 12.4 0.6 1.1 1 0 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like DUF4047 PF13256.1 CCC70772.1 - 0.22 11.5 2.3 0.42 10.5 1.6 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) DASH_Dad1 PF08649.5 CCC70772.1 - 0.74 9.5 6.9 18 5.1 4.8 2.1 1 1 0 1 1 1 0 DASH complex subunit Dad1 Asparaginase PF00710.15 CCC70773.1 - 2.1e-72 243.6 0.0 2.5e-72 243.4 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ribosomal_L19 PF01245.15 CCC70773.1 - 0.026 14.2 0.0 4.5 7.0 0.0 3.0 3 0 0 3 3 3 0 Ribosomal protein L19 HMG_box PF00505.14 CCC70774.1 - 3.4e-06 27.2 12.5 8.6e-06 25.9 0.3 3.9 3 1 0 3 3 3 2 HMG (high mobility group) box PsbU PF06514.6 CCC70774.1 - 3.4 7.5 7.9 0.16 11.8 0.4 2.6 3 0 0 3 3 3 0 Photosystem II 12 kDa extrinsic protein (PsbU) DUF2481 PF10654.4 CCC70774.1 - 8.5 6.0 14.4 0.058 13.0 2.4 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2481) ATP-synt_E PF05680.7 CCC70776.1 - 6.1e-12 45.3 0.0 6.5e-12 45.2 0.0 1.1 1 0 0 1 1 1 1 ATP synthase E chain Cas_NE0113 PF09623.5 CCC70776.1 - 0.14 11.6 0.1 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) FYVE PF01363.16 CCC70777.1 - 1.7e-20 72.7 24.5 9.8e-17 60.6 1.4 3.3 3 0 0 3 3 3 2 FYVE zinc finger Rbsn PF11464.3 CCC70777.1 - 1.1e-05 24.8 0.1 1.1e-05 24.8 0.1 2.2 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-Di19 PF05605.7 CCC70777.1 - 0.0037 17.3 0.2 0.0037 17.3 0.1 2.0 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 CCC70777.1 - 0.068 13.5 0.5 0.068 13.5 0.3 4.5 4 1 0 4 4 4 0 C2H2-type zinc finger WD40 PF00400.27 CCC70778.1 - 1.3e-16 59.7 16.6 0.011 15.5 0.1 8.4 9 0 0 9 9 9 6 WD domain, G-beta repeat IKI3 PF04762.7 CCC70778.1 - 0.0045 14.8 2.3 0.15 9.7 0.3 2.4 2 1 0 2 2 2 2 IKI3 family Cnd3 PF12719.2 CCC70779.1 - 7.4e-99 330.5 3.0 7.4e-99 330.5 2.1 3.0 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 CCC70779.1 - 3.8e-10 39.8 0.0 1.9e-06 28.0 0.0 3.7 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 CCC70779.1 - 1.4e-06 27.8 0.1 0.4 10.9 0.0 4.4 3 0 0 3 3 3 2 HEAT repeat HEAT_EZ PF13513.1 CCC70779.1 - 0.00035 20.9 0.1 0.1 13.1 0.0 3.4 2 1 1 3 3 3 1 HEAT-like repeat DUF4042 PF13251.1 CCC70779.1 - 0.0096 15.4 0.8 0.71 9.3 0.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4042) GRAM PF02893.15 CCC70780.1 - 3.4e-17 61.7 0.0 7.5e-17 60.6 0.0 1.6 1 0 0 1 1 1 1 GRAM domain Skp1 PF01466.14 CCC70781.1 - 1.3e-36 124.4 0.3 1.3e-36 124.4 0.2 1.9 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 CCC70781.1 - 4.6e-14 52.2 0.2 3.4e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Skp1 family, tetramerisation domain TRM13 PF05206.9 CCC70781.1 - 0.097 11.8 0.5 0.17 11.0 0.3 1.4 1 0 0 1 1 1 0 Methyltransferase TRM13 DNA_pol_phi PF04931.8 CCC70781.1 - 0.29 8.8 11.4 0.35 8.5 7.9 1.1 1 0 0 1 1 1 0 DNA polymerase phi Peroxin-3 PF04882.7 CCC70782.1 - 1.6e-83 280.8 17.9 9.5e-69 232.1 7.9 2.0 1 1 1 2 2 2 2 Peroxin-3 Nnf1 PF03980.9 CCC70782.1 - 0.071 13.1 5.8 0.23 11.4 0.4 3.0 3 0 0 3 3 3 0 Nnf1 3-PAP PF12578.3 CCC70782.1 - 0.23 11.3 6.7 0.08 12.7 0.5 2.8 4 0 0 4 4 4 0 Myotubularin-associated protein CcmD PF04995.9 CCC70782.1 - 5.5 6.7 6.1 31 4.4 1.3 2.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Thioredoxin_7 PF13899.1 CCC70783.1 - 1e-18 67.1 0.0 2.4e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 CCC70783.1 - 1.3e-15 57.2 0.0 2.5e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 CCC70783.1 - 3.6e-14 52.0 1.6 8.2e-14 50.8 1.1 1.7 1 0 0 1 1 1 1 UBA-like domain C2-set PF05790.10 CCC70783.1 - 8.1e-05 22.5 0.1 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 Immunoglobulin C2-set domain Thioredox_DsbH PF03190.10 CCC70783.1 - 0.0041 16.8 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF255 CDC45 PF02724.9 CCC70783.1 - 1.7 6.5 10.6 0.2 9.6 1.1 2.2 2 0 0 2 2 2 0 CDC45-like protein Nop14 PF04147.7 CCC70783.1 - 1.9 6.3 21.2 0.18 9.6 6.0 2.1 2 0 0 2 2 2 0 Nop14-like family Peptidase_C13 PF01650.13 CCC70784.1 - 4.7e-47 160.4 1.2 6.8e-47 159.9 0.8 1.2 1 0 0 1 1 1 1 Peptidase C13 family ResIII PF04851.10 CCC70785.1 - 1e-23 84.1 1.3 4.1e-23 82.1 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCC70785.1 - 2.8e-14 52.9 0.1 8.7e-14 51.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC70785.1 - 4.1e-11 42.5 0.1 2.8e-10 39.9 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF2075 PF09848.4 CCC70785.1 - 0.0045 16.0 0.0 0.013 14.5 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CCC70785.1 - 0.046 13.8 0.0 0.17 12.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain STE PF02200.11 CCC70786.1 - 3.5e-59 197.7 2.9 5.8e-59 197.0 2.0 1.4 1 0 0 1 1 1 1 STE like transcription factor Tcf25 PF04910.9 CCC70787.1 - 3.8e-80 269.5 0.1 3.8e-80 269.5 0.1 1.9 2 0 0 2 2 2 1 Transcriptional repressor TCF25 Rotamase PF00639.16 CCC70787.1 - 0.12 13.1 4.5 2 9.1 3.2 2.7 2 0 0 2 2 2 0 PPIC-type PPIASE domain ARD PF03079.9 CCC70787.1 - 0.26 11.2 7.6 0.76 9.7 5.3 1.8 1 0 0 1 1 1 0 ARD/ARD' family NST1 PF13945.1 CCC70787.1 - 0.35 10.9 14.9 0.81 9.7 10.4 1.6 1 0 0 1 1 1 0 Salt tolerance down-regulator Ipi1_N PF12333.3 CCC70788.1 - 2.3e-25 88.5 1.0 1.6e-24 85.8 0.1 2.6 2 1 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation HEAT PF02985.17 CCC70788.1 - 0.025 14.6 0.5 1.3 9.2 0.0 3.2 3 0 0 3 3 3 0 HEAT repeat SNF2_N PF00176.18 CCC70789.1 - 5e-77 258.6 0.8 5e-77 258.6 0.5 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCC70789.1 - 5.6e-14 51.7 0.0 1.9e-13 50.0 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.8 CCC70789.1 - 5.6e-13 48.4 3.2 5.6e-13 48.4 2.2 2.6 1 1 1 2 2 2 1 HSA DEAD PF00270.24 CCC70789.1 - 1.3e-07 31.2 0.0 4.9e-07 29.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase MMR_HSR1 PF01926.18 CCC70790.1 - 1e-14 54.4 0.0 1.9e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCC70790.1 - 5.7e-05 22.3 0.0 9.4e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCC70790.1 - 8.3e-05 22.0 0.0 0.00067 19.1 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 CCC70790.1 - 9e-05 21.8 0.0 0.00016 21.0 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCC70790.1 - 0.00037 20.3 0.1 0.2 11.4 0.0 2.6 2 1 1 3 3 3 2 Dynamin family SRPRB PF09439.5 CCC70790.1 - 0.00054 19.2 0.0 0.00085 18.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 CCC70790.1 - 0.0023 17.4 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AIG1 PF04548.11 CCC70790.1 - 0.018 14.1 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 AIG1 family AAA_23 PF13476.1 CCC70790.1 - 0.053 13.8 0.1 0.082 13.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 CCC70790.1 - 0.072 11.9 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 CCC70790.1 - 0.079 13.2 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_21 PF13304.1 CCC70790.1 - 5.3 6.9 8.1 5.9 6.7 1.1 2.3 2 1 0 2 2 2 0 AAA domain Ribosomal_S15 PF00312.17 CCC70791.1 - 2.7e-28 97.5 0.4 5.4e-28 96.5 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S15 MatE PF01554.13 CCC70792.1 - 1.2e-60 203.7 31.9 6.9e-34 116.8 5.5 2.8 3 0 0 3 3 3 2 MatE Fcf1 PF04900.7 CCC70793.1 - 1.9e-37 127.3 0.6 3e-37 126.7 0.1 1.6 2 0 0 2 2 2 1 Fcf1 Sugar_tr PF00083.19 CCC70794.1 - 2.1e-173 577.0 36.3 2.5e-173 576.7 25.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC70794.1 - 3.9e-31 108.0 36.7 1.5e-27 96.2 14.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCC70794.1 - 0.74 7.8 6.8 0.31 9.1 3.0 1.6 2 0 0 2 2 2 0 Transmembrane secretion effector Sugar_tr PF00083.19 CCC70795.1 - 4.1e-174 579.4 35.0 4.7e-174 579.2 24.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC70795.1 - 3.7e-31 108.1 32.5 4e-30 104.7 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Svf1 PF08622.5 CCC70796.1 - 6.4e-135 449.3 5.5 8e-135 448.9 3.8 1.1 1 0 0 1 1 1 1 Svf1-like Spore_coat_CotO PF14153.1 CCC70796.1 - 0.00093 18.6 4.9 0.0014 18.1 3.4 1.3 1 0 0 1 1 1 1 Spore coat protein CotO Ycf1 PF05758.7 CCC70796.1 - 0.043 11.5 4.0 0.052 11.2 2.8 1.1 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 CCC70796.1 - 0.057 11.3 12.5 0.073 10.9 8.7 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 CCC70796.1 - 0.14 10.5 16.4 0.2 10.1 11.4 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 CCC70796.1 - 0.18 9.8 9.4 0.23 9.4 6.5 1.1 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.8 CCC70796.1 - 1.3 7.5 5.9 1.9 6.9 4.1 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.17 CCC70796.1 - 2.2 7.2 4.6 4.1 6.3 1.6 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter eIF-3c_N PF05470.7 CCC70796.1 - 6.7 4.6 14.6 5.3 5.0 9.0 1.5 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sod_Fe_C PF02777.13 CCC70797.1 - 3.2e-10 39.8 1.8 0.00014 21.6 0.1 2.9 2 1 1 3 3 3 2 Iron/manganese superoxide dismutases, C-terminal domain Pal1 PF08316.6 CCC70798.1 - 6.7e-53 178.9 3.3 6.7e-53 178.9 2.3 3.1 2 2 1 3 3 3 1 Pal1 cell morphology protein Asp PF00026.18 CCC70799.1 - 2.2e-19 69.8 2.6 7e-19 68.2 0.1 2.8 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 CCC70799.1 - 8.6e-05 22.5 2.6 0.00011 22.1 0.1 2.4 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal FAT PF02259.18 CCC70800.1 - 3.6e-71 239.9 6.8 8.3e-71 238.8 4.7 1.7 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 CCC70800.1 - 4.4e-37 127.8 2.8 8e-37 126.9 0.7 2.5 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 CCC70800.1 - 2.8e-07 29.8 0.0 7.5e-07 28.4 0.0 1.8 1 0 0 1 1 1 1 FATC domain PQ-loop PF04193.9 CCC70803.1 - 7e-37 124.7 9.5 5.8e-19 67.4 0.8 2.5 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 CCC70803.1 - 0.07 13.0 9.2 0.092 12.6 0.1 3.4 2 2 1 3 3 3 0 Sugar efflux transporter for intercellular exchange Pyr_redox_2 PF07992.9 CCC70804.1 - 9.1e-28 97.5 0.0 2.8e-27 95.9 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCC70804.1 - 1.2e-19 70.4 0.1 3e-16 59.6 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCC70804.1 - 2.1e-10 40.9 0.0 4.8e-07 30.0 0.0 2.4 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCC70804.1 - 1.1e-05 24.5 0.7 0.48 9.2 0.1 3.9 4 0 0 4 4 4 2 Glucose inhibited division protein A Thi4 PF01946.12 CCC70804.1 - 6.4e-05 22.1 0.2 0.0013 17.9 0.0 2.4 2 1 0 2 2 2 1 Thi4 family NAD_binding_7 PF13241.1 CCC70804.1 - 7.1e-05 23.0 0.0 0.022 15.0 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 CCC70804.1 - 0.00029 20.9 0.1 0.36 10.9 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 CCC70804.1 - 0.00059 19.8 0.1 0.031 14.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 CCC70804.1 - 0.00067 18.6 0.1 0.33 9.8 0.0 3.2 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 CCC70804.1 - 0.0032 16.4 0.0 4 6.2 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 CCC70804.1 - 0.014 14.4 0.1 4.1 6.3 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_Gly3P_dh_N PF01210.18 CCC70804.1 - 0.015 15.0 0.1 7 6.3 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_binding_2 PF00890.19 CCC70804.1 - 0.015 14.1 1.2 2.1 7.1 0.2 2.8 2 1 1 3 3 3 0 FAD binding domain HI0933_like PF03486.9 CCC70804.1 - 0.056 11.9 0.3 1.5 7.2 0.1 2.6 2 1 1 3 3 3 0 HI0933-like protein Glycos_transf_3 PF00591.16 CCC70805.1 - 1.1e-82 277.2 0.0 1.4e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 CCC70805.1 - 1.8e-11 43.4 0.1 5.7e-11 41.8 0.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase family, helical bundle domain NumbF PF06311.7 CCC70806.1 - 0.0014 18.7 0.2 0.0085 16.1 0.2 2.4 1 0 0 1 1 1 1 NUMB domain PACT_coil_coil PF10495.4 CCC70806.1 - 0.002 17.9 0.7 0.011 15.6 0.5 2.3 1 1 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein Reo_sigmaC PF04582.7 CCC70806.1 - 0.006 15.8 2.3 0.006 15.8 1.6 5.5 2 1 4 6 6 6 1 Reovirus sigma C capsid protein DUF2365 PF10157.4 CCC70807.1 - 0.061 13.2 0.5 0.072 12.9 0.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2365) DASH_Dam1 PF08653.5 CCC70807.1 - 0.066 12.9 2.0 2.1 8.1 0.3 2.2 2 0 0 2 2 2 0 DASH complex subunit Dam1 VHS PF00790.14 CCC70808.1 - 1.5e-48 163.9 0.1 8.9e-48 161.5 0.0 2.2 2 0 0 2 2 2 1 VHS domain Alpha_adaptinC2 PF02883.15 CCC70808.1 - 4.7e-21 75.2 0.1 9e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain GAT PF03127.9 CCC70808.1 - 2.1e-14 53.2 2.7 7e-14 51.6 1.9 1.9 1 0 0 1 1 1 1 GAT domain DUF3783 PF12646.2 CCC70808.1 - 0.19 11.5 1.9 0.56 10.0 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) HSA PF07529.8 CCC70809.1 - 7.2e-19 67.3 0.0 7.2e-19 67.3 0.0 2.9 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.1 CCC70809.1 - 1e-08 35.1 0.1 3.6e-08 33.3 0.1 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain BCIP PF13862.1 CCC70810.1 - 6.9e-50 169.2 0.6 9.5e-50 168.8 0.4 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein RRN3 PF05327.6 CCC70810.1 - 7.2 4.5 8.2 0.34 8.9 1.0 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 ThiF PF00899.16 CCC70811.1 - 7.4e-43 145.6 0.0 1.3e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 CCC70811.1 - 4.5e-26 90.2 0.2 8e-26 89.4 0.1 1.4 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 CCC70811.1 - 8.2e-14 51.9 0.0 1.7e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 CCC70811.1 - 5.2e-05 23.3 0.0 0.00017 21.7 0.0 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Herpes_BLRF2 PF05812.7 CCC70811.1 - 0.0017 18.1 0.2 0.0033 17.2 0.2 1.4 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein MscS_porin PF12795.2 CCC70811.1 - 0.033 13.4 0.2 0.063 12.5 0.1 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain WD40 PF00400.27 CCC70812.1 - 0.091 12.6 5.1 0.52 10.2 0.3 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Cys_Met_Meta_PP PF01053.15 CCC70813.1 - 1.1e-66 224.6 0.0 3.2e-66 223.1 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 CCC70813.1 - 5e-06 25.5 0.0 7.9e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V gag_pre-integrs PF13976.1 CCC70813.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 GAG-pre-integrase domain Shisa PF13908.1 CCC70814.1 - 3.7e-06 27.2 3.9 3.7e-06 27.2 2.7 1.5 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator TMEM51 PF15345.1 CCC70814.1 - 0.00057 19.6 0.2 0.0007 19.3 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 Tetraspannin PF00335.15 CCC70814.1 - 0.00077 18.7 1.5 0.0019 17.5 1.1 1.5 1 1 0 1 1 1 1 Tetraspanin family Chordopox_A33R PF05966.7 CCC70814.1 - 0.012 14.3 0.1 0.02 13.6 0.1 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Zip PF02535.17 CCC70814.1 - 0.024 13.6 0.2 0.031 13.2 0.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Bul1_N PF04425.7 CCC70814.1 - 0.18 10.3 8.3 0.24 9.9 5.7 1.2 1 0 0 1 1 1 0 Bul1 N terminus Rad60-SLD PF11976.3 CCC70815.1 - 4.5e-26 90.3 1.7 3.5e-25 87.4 0.6 2.7 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like DSS1_SEM1 PF05160.8 CCC70816.1 - 1.8e-19 69.2 17.1 1.8e-19 69.2 11.9 1.4 1 1 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.7 CCC70816.1 - 0.12 12.0 9.1 0.14 11.8 6.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Y_phosphatase PF00102.22 CCC70816.1 - 1.2 8.4 4.6 1.8 7.8 3.2 1.4 1 1 0 1 1 1 0 Protein-tyrosine phosphatase AAA PF00004.24 CCC70817.1 - 1.3e-41 141.8 0.0 3.2e-41 140.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 CCC70817.1 - 6.5e-06 26.1 0.1 0.00017 21.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 CCC70817.1 - 4.2e-05 23.6 0.5 0.01 15.8 0.0 2.7 2 1 1 3 3 2 1 AAA ATPase domain AAA_5 PF07728.9 CCC70817.1 - 6e-05 22.7 1.6 0.00021 21.0 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCC70817.1 - 0.00061 19.9 1.8 0.0078 16.3 0.2 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 CCC70817.1 - 0.00066 18.7 0.0 0.0015 17.6 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CCC70817.1 - 0.0018 18.1 0.0 0.017 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CCC70817.1 - 0.0041 16.3 0.2 0.035 13.3 0.1 2.2 2 0 0 2 2 2 1 PhoH-like protein AAA_17 PF13207.1 CCC70817.1 - 0.006 17.4 0.0 0.021 15.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 CCC70817.1 - 0.0084 15.5 0.0 0.017 14.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 CCC70817.1 - 0.0096 15.6 0.2 0.024 14.3 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain Mg_chelatase PF01078.16 CCC70817.1 - 0.011 14.8 0.1 0.031 13.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 CCC70817.1 - 0.015 14.1 0.0 0.03 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 CCC70817.1 - 0.021 14.7 0.4 0.09 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 CCC70817.1 - 0.029 13.7 0.8 0.24 10.7 0.1 2.2 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 CCC70817.1 - 0.07 12.6 1.2 0.14 11.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 CCC70817.1 - 0.082 13.0 0.1 0.53 10.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase BLOC1_2 PF10046.4 CCC70817.1 - 0.17 12.0 5.1 0.08 13.0 1.2 2.3 3 0 0 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 KaiC PF06745.8 CCC70817.1 - 0.22 10.6 2.2 0.35 9.9 0.0 2.3 3 0 0 3 3 3 0 KaiC ThylakoidFormat PF11264.3 CCC70817.1 - 0.31 10.6 4.6 0.43 10.1 2.5 1.7 2 0 0 2 2 2 0 Thylakoid formation protein WD40 PF00400.27 CCC70818.1 - 2.3e-39 131.8 12.1 1.2e-10 40.8 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 CCC70818.1 - 0.15 10.7 0.6 0.89 8.2 0.0 2.1 1 1 2 3 3 3 0 Coatomer WD associated region NUC153 PF08159.7 CCC70819.1 - 1e-13 50.6 14.9 4.1e-13 48.6 3.9 3.0 3 0 0 3 3 3 2 NUC153 domain RIO1 PF01163.17 CCC70820.1 - 1.7e-74 249.2 2.5 1.7e-74 249.2 1.7 2.9 3 0 0 3 3 3 1 RIO1 family Pkinase PF00069.20 CCC70820.1 - 1.2e-05 24.5 0.4 1.2e-05 24.5 0.2 2.5 4 0 0 4 4 4 1 Protein kinase domain APH PF01636.18 CCC70820.1 - 0.0017 18.1 0.1 0.21 11.3 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family EBV-NA3 PF05009.7 CCC70820.1 - 8.8 5.5 9.6 1.1 8.4 0.3 2.3 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Kei1 PF08552.6 CCC70821.1 - 4.1e-50 170.0 16.0 6.4e-41 140.0 7.0 2.0 1 1 1 2 2 2 2 Inositolphosphorylceramide synthase subunit Kei1 Aldo_ket_red PF00248.16 CCC70822.1 - 2.5e-47 161.0 0.0 3.1e-47 160.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FHA PF00498.21 CCC70823.1 - 3.8e-06 26.9 0.3 1.4e-05 25.0 0.2 2.0 1 0 0 1 1 1 1 FHA domain RAI1 PF08652.6 CCC70824.1 - 1.7e-05 24.5 0.1 6.4e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease YCII PF03795.9 CCC70825.1 - 1.2e-06 28.5 0.0 1.6e-06 28.2 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain GPP34 PF05719.6 CCC70827.1 - 1.5e-59 201.5 0.0 1.9e-59 201.2 0.0 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) EF-hand_7 PF13499.1 CCC70828.1 - 1.1e-28 99.0 12.4 1.9e-14 53.5 0.7 3.4 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.27 CCC70828.1 - 1.1e-26 90.0 5.9 3.8e-07 28.9 0.3 4.6 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 CCC70828.1 - 2.3e-23 79.9 4.7 7.4e-06 25.4 0.1 4.8 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 CCC70828.1 - 2.3e-23 81.5 4.9 9.4e-12 44.3 0.0 3.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 CCC70828.1 - 1.2e-18 65.4 3.4 3.7e-05 22.8 0.2 4.5 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 CCC70828.1 - 4.3e-05 23.1 3.5 1.7 8.4 0.0 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 CCC70828.1 - 0.00041 20.1 0.4 0.025 14.4 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 CCC70828.1 - 0.00044 20.2 1.0 0.094 12.7 0.1 3.1 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 CCC70828.1 - 0.025 14.2 0.3 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 EF hand S10_plectin PF03501.10 CCC70828.1 - 0.054 13.3 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 Plectin/S10 domain Tenui_NCP PF04876.7 CCC70828.1 - 0.099 12.1 0.0 0.56 9.7 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein EF-hand_2 PF09068.6 CCC70828.1 - 0.11 12.5 0.0 5 7.2 0.0 2.2 2 0 0 2 2 2 0 EF hand Acyltransferase PF01553.16 CCC70829.1 - 0.0025 17.2 0.0 0.01 15.2 0.0 1.9 1 1 0 1 1 1 1 Acyltransferase Acyltransferase PF01553.16 CCC70830.1 - 1.2e-12 47.4 0.0 2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Kinesin PF00225.18 CCC70831.1 - 1.4e-102 342.8 3.3 1.4e-102 342.8 2.3 2.4 2 1 1 3 3 3 1 Kinesin motor domain IncA PF04156.9 CCC70831.1 - 0.15 11.6 60.7 0.92 9.0 12.0 3.3 1 1 2 3 3 3 0 IncA protein Rrp15p PF07890.7 CCC70832.1 - 5.3e-32 110.6 14.7 5.3e-32 110.6 10.2 2.2 2 1 0 2 2 2 1 Rrp15p Metallophos PF00149.23 CCC70833.1 - 1.7e-37 128.7 0.0 2.8e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TPR_11 PF13414.1 CCC70833.1 - 3.8e-21 74.5 1.3 3.6e-18 64.9 0.2 3.0 1 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 CCC70833.1 - 9.8e-14 50.2 3.7 1.7e-08 33.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat PPP5 PF08321.7 CCC70833.1 - 7.6e-13 48.3 0.5 1.1e-05 25.3 0.0 3.1 2 1 1 3 3 3 2 PPP5 TPR repeat region TPR_2 PF07719.12 CCC70833.1 - 2.4e-12 45.7 0.1 7.3e-05 22.3 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 CCC70833.1 - 3.1e-06 26.9 1.1 0.081 13.1 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCC70833.1 - 3.8e-06 27.1 1.7 6.4e-05 23.2 0.1 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 CCC70833.1 - 4e-06 26.5 0.1 0.00095 18.9 0.1 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCC70833.1 - 0.00048 20.7 0.1 0.19 12.4 0.0 2.9 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 CCC70833.1 - 0.0054 17.2 0.2 5 8.0 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat TFIIB PF00382.14 CCC70833.1 - 0.01 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Transcription factor TFIIB repeat NBP1 PF08537.5 CCC70833.1 - 0.016 14.3 0.2 0.03 13.5 0.2 1.3 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Fis1_TPR_C PF14853.1 CCC70833.1 - 0.031 14.1 1.8 0.35 10.7 0.0 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 CCC70833.1 - 0.034 13.9 0.1 0.17 11.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 CCC70833.1 - 0.064 13.0 0.3 0.32 10.8 0.2 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 CCC70833.1 - 0.1 12.5 2.9 0.19 11.6 0.2 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_15 PF13429.1 CCC70833.1 - 0.18 10.8 0.5 6.9 5.6 0.0 2.7 1 1 2 3 3 3 0 Tetratricopeptide repeat CBF PF03914.12 CCC70834.1 - 1.2e-45 154.9 0.8 9.1e-45 152.0 0.8 2.1 2 1 0 2 2 2 1 CBF/Mak21 family Asn_synthase PF00733.16 CCC70835.1 - 1.6e-69 234.2 0.0 2.3e-69 233.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 CCC70835.1 - 3.8e-35 120.3 0.0 6.3e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 CCC70835.1 - 1.6e-28 99.2 0.0 5.4e-28 97.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 CCC70835.1 - 1.8e-07 30.6 0.0 3.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 CCC70835.1 - 0.00013 20.8 0.0 0.25 10.0 0.0 3.0 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 CCC70835.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD synthase DUF2305 PF10230.4 CCC70837.1 - 7.1e-69 232.1 1.3 8.1e-69 231.9 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 CCC70837.1 - 0.035 13.7 0.1 0.066 12.8 0.0 1.5 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_5 PF12695.2 CCC70837.1 - 0.083 12.6 0.0 0.085 12.6 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family BAR_2 PF10455.4 CCC70838.1 - 4.9e-82 275.0 54.4 3e-79 265.9 37.7 3.3 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Mlf1IP PF10248.4 CCC70839.1 - 0.024 14.2 0.4 0.061 12.9 0.3 1.7 1 0 0 1 1 1 0 Myelodysplasia-myeloid leukemia factor 1-interacting protein Cytochrom_C PF00034.16 CCC70839.1 - 0.31 11.8 1.8 1.3 9.9 0.0 2.9 2 1 0 2 2 2 0 Cytochrome c IncA PF04156.9 CCC70839.1 - 5.4 6.5 11.8 0.58 9.7 3.7 2.5 2 0 0 2 2 2 0 IncA protein MARVEL PF01284.18 CCC70840.1 - 5.1e-24 84.7 15.9 6.5e-24 84.3 11.1 1.1 1 0 0 1 1 1 1 Membrane-associating domain MerC PF03203.9 CCC70840.1 - 0.0039 17.5 3.8 0.03 14.6 0.4 2.3 2 1 0 2 2 2 1 MerC mercury resistance protein DUF4345 PF14248.1 CCC70840.1 - 0.012 15.0 0.7 0.012 15.0 0.5 2.4 2 1 0 3 3 3 0 Domain of unknown function (DUF4345) Tetraspannin PF00335.15 CCC70840.1 - 0.71 9.1 16.4 0.18 11.0 7.4 2.0 1 1 1 2 2 2 0 Tetraspanin family Pet20 PF08692.5 CCC70841.1 - 2e-26 92.5 7.4 3.3e-24 85.3 3.2 2.5 2 1 0 2 2 2 1 Mitochondrial protein Pet20 WW PF00397.21 CCC70842.1 - 6e-09 35.6 4.6 6e-09 35.6 3.2 2.7 3 0 0 3 3 3 1 WW domain FF PF01846.14 CCC70842.1 - 6e-06 26.1 1.7 6e-06 26.1 1.2 2.6 2 0 0 2 2 2 1 FF domain DUF1635 PF07795.6 CCC70842.1 - 0.55 9.5 5.0 0.8 9.0 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Tmemb_170 PF10190.4 CCC70843.1 - 0.0003 20.8 6.4 0.00035 20.6 4.4 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 DUF457 PF04307.9 CCC70843.1 - 0.97 8.7 7.8 0.17 11.2 1.9 2.0 1 1 1 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) Gly-zipper_YMGG PF13441.1 CCC70843.1 - 8.2 6.0 9.1 0.37 10.3 2.2 1.7 2 0 0 2 2 2 0 YMGG-like Gly-zipper SH3_1 PF00018.23 CCC70844.1 - 1.1e-15 56.6 0.0 2.3e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 CCC70844.1 - 6.9e-15 54.3 0.0 1.1e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 CCC70844.1 - 1.6e-09 37.1 0.0 2.4e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF4496 PF14908.1 CCC70844.1 - 0.2 11.5 3.1 0.35 10.7 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4496) PAT1 PF09770.4 CCC70844.1 - 0.68 8.0 30.1 0.86 7.7 20.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 NCA2 PF08637.5 CCC70845.1 - 2.3e-94 315.5 7.4 4.3e-94 314.6 5.1 1.5 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 MFS_1 PF07690.11 CCC70846.1 - 6.9e-32 110.5 31.8 6.9e-32 110.5 22.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF946 PF06101.6 CCC70847.1 - 2.7e-08 32.2 3.4 2.6e-07 29.0 2.3 2.0 1 1 0 1 1 1 1 Plant protein of unknown function (DUF946) SKN1 PF03935.10 CCC70849.1 - 3.9e-257 853.3 6.9 5.3e-257 852.8 4.8 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Anophelin PF10731.4 CCC70849.1 - 0.38 10.8 2.0 1.4 9.0 1.4 2.0 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito Phosphorylase PF00343.15 CCC70850.1 - 0 1043.1 2.5 0 1042.9 1.8 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase CDP-OH_P_transf PF01066.16 CCC70851.1 - 7.4e-11 42.2 3.4 1.4e-10 41.3 2.4 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Clathrin PF00637.15 CCC70852.1 - 4.2e-192 629.4 62.2 1.1e-33 115.8 1.7 8.0 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.1 CCC70852.1 - 7e-25 86.6 1.9 1.5e-24 85.6 0.3 2.5 2 0 0 2 2 2 1 Clathrin-H-link Clathrin_propel PF01394.15 CCC70852.1 - 1.5e-15 56.3 7.0 0.00099 19.2 0.1 6.7 6 0 0 6 6 6 5 Clathrin propeller repeat Clathrin-link PF09268.5 CCC70852.1 - 2.6e-09 35.8 0.4 2.6e-09 35.8 0.2 3.0 4 0 0 4 4 4 1 Clathrin, heavy-chain linker V-set PF07686.12 CCC70853.1 - 0.14 12.0 1.1 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Immunoglobulin V-set domain SPT16 PF08644.6 CCC70856.1 - 9.1e-51 171.6 0.1 2.7e-50 170.1 0.1 1.9 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 CCC70856.1 - 1.1e-48 164.8 2.7 1.7e-48 164.1 0.1 2.7 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 CCC70856.1 - 5.1e-24 85.0 0.0 9.9e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 CCC70856.1 - 1.1e-18 67.0 0.2 1.3e-17 63.5 0.1 2.9 2 0 0 2 2 2 1 Histone chaperone Rttp106-like AMPKBI PF04739.10 CCC70857.1 - 1.5e-32 111.4 4.1 1.5e-32 111.4 2.8 2.8 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Ndc1_Nup PF09531.5 CCC70857.1 - 0.45 8.8 3.5 0.63 8.4 2.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CENP-T PF15511.1 CCC70857.1 - 0.98 8.5 17.9 8.8 5.4 0.1 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T zf-H2C2_2 PF13465.1 CCC70858.1 - 2.1e-09 37.2 18.6 1.4e-06 28.2 4.5 3.4 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 CCC70858.1 - 1.3e-08 34.6 14.9 1.7e-05 24.8 1.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC70858.1 - 2.5e-06 27.4 15.3 0.00041 20.4 0.7 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCC70858.1 - 0.0047 17.0 1.3 0.5 10.5 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding LSM PF01423.17 CCC70859.1 - 5.5e-19 67.4 0.7 1e-18 66.6 0.5 1.4 1 0 0 1 1 1 1 LSM domain CHZ PF09649.5 CCC70860.1 - 8.4e-20 69.7 2.1 8.4e-20 69.7 1.5 3.1 3 0 0 3 3 3 1 Histone chaperone domain CHZ Astro_capsid PF03115.9 CCC70860.1 - 4.8 5.3 10.0 5 5.2 6.9 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Hid1 PF12722.2 CCC70863.1 - 8.2 3.9 11.5 9.5 3.7 7.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FAM60A PF15396.1 CCC70864.1 - 0.38 10.4 11.1 0.13 12.0 5.8 1.5 1 1 1 2 2 2 0 Protein Family FAM60A HAD_2 PF13419.1 CCC70865.1 - 2.5e-24 86.4 0.1 3.5e-24 85.9 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC70865.1 - 6.4e-06 26.7 0.0 0.0022 18.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCC70865.1 - 0.00098 18.7 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Nse5 PF08691.5 CCC70866.1 - 5e-24 84.6 19.0 5e-24 84.6 13.2 1.3 1 1 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 UAA PF08449.6 CCC70867.1 - 2.6e-12 46.3 24.3 3.3e-12 45.9 16.8 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CCC70867.1 - 1.3e-10 41.1 8.1 1.3e-10 41.1 5.6 2.7 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 CCC70867.1 - 3.3e-06 27.1 33.9 0.00095 19.2 5.6 2.3 2 0 0 2 2 2 2 EamA-like transporter family Multi_Drug_Res PF00893.14 CCC70867.1 - 7.3 7.1 14.7 24 5.4 5.1 3.0 2 1 1 3 3 3 0 Small Multidrug Resistance protein GATA PF00320.22 CCC70868.1 - 2.1e-16 58.9 2.8 4.6e-16 57.8 2.0 1.6 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 CCC70868.1 - 0.16 11.3 0.4 0.35 10.2 0.3 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding XPG_I PF00867.13 CCC70869.1 - 4.4e-18 65.1 0.0 1.9e-17 63.1 0.0 2.2 2 1 0 2 2 2 1 XPG I-region XPG_N PF00752.12 CCC70869.1 - 0.0058 16.8 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain PMSR PF01625.16 CCC70870.1 - 2e-49 167.4 1.6 2.6e-49 167.0 1.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF4298 PF14131.1 CCC70870.1 - 0.019 14.7 0.8 0.048 13.5 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) AdoHcyase PF05221.12 CCC70871.1 - 1.3e-139 463.6 0.1 1.5e-139 463.4 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 CCC70871.1 - 2.4e-85 284.3 2.1 3.8e-85 283.6 1.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 CCC70871.1 - 2.2e-07 30.1 0.1 4.1e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 CCC70871.1 - 0.0014 18.0 0.3 0.0025 17.1 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 CCC70871.1 - 0.009 16.0 0.1 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 CCC70871.1 - 0.036 13.6 0.1 0.058 12.9 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.16 CCC70871.1 - 0.044 13.3 0.3 0.09 12.3 0.2 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Urocanase PF01175.13 CCC70871.1 - 0.063 11.3 0.2 0.086 10.8 0.1 1.2 1 0 0 1 1 1 0 Urocanase RPM2 PF08579.6 CCC70871.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial ribonuclease P subunit (RPM2) SAPS PF04499.10 CCC70873.1 - 2.5e-157 524.3 10.9 2.5e-157 524.3 7.5 2.0 2 0 0 2 2 2 1 SIT4 phosphatase-associated protein DnaJ PF00226.26 CCC70874.1 - 3.5e-12 45.8 3.9 8.1e-12 44.7 2.4 1.9 2 0 0 2 2 2 1 DnaJ domain Peptidase_M20 PF01546.23 CCC70876.1 - 2.3e-28 98.9 0.0 4.4e-28 98.0 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCC70876.1 - 2.9e-13 49.5 0.0 6e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Mito_carr PF00153.22 CCC70877.1 - 1.4e-45 152.9 4.6 5.8e-20 70.8 0.0 4.6 3 2 0 3 3 3 3 Mitochondrial carrier protein IBN_N PF03810.14 CCC70879.1 - 1.9e-12 46.9 1.6 1.6e-11 43.9 0.1 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Ank PF00023.25 CCC70880.1 - 2.4e-12 45.9 0.2 0.00026 20.6 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 CCC70880.1 - 5.1e-10 39.5 0.1 3.5e-08 33.6 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 CCC70880.1 - 1.5e-08 34.0 0.0 0.0016 18.5 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CCC70880.1 - 1.7e-08 34.7 0.8 4.6e-05 23.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 CCC70880.1 - 2.2e-08 34.0 0.1 3.5e-05 23.9 0.0 3.8 3 1 1 4 4 4 1 Ankyrin repeats (many copies) DUF155 PF02582.9 CCC70881.1 - 2.9e-58 196.6 0.2 4.8e-58 195.9 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Brr6_like_C_C PF10104.4 CCC70882.1 - 1.3e-41 141.2 3.2 1.7e-41 140.8 2.2 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF3671 PF12420.3 CCC70882.1 - 0.085 12.8 0.4 0.3 11.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function DUF2638 PF10937.3 CCC70883.1 - 4.4e-28 98.5 0.0 5.5e-28 98.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) Proteasome PF00227.21 CCC70884.1 - 2.9e-24 85.4 0.0 3.9e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Clat_adaptor_s PF01217.15 CCC70885.1 - 3.4e-08 33.3 1.2 7.2e-08 32.2 0.8 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Adap_comp_sub PF00928.16 CCC70885.1 - 3.8e-08 32.7 0.1 6e-08 32.0 0.1 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Ppx-GppA PF02541.11 CCC70886.1 - 5.3e-67 225.9 0.0 7.5e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Ppx/GppA phosphatase family SAC3_GANP PF03399.11 CCC70887.1 - 3.3e-29 101.9 0.4 4.6e-29 101.4 0.3 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 CCC70887.1 - 1.2e-20 73.7 0.9 2.1e-20 72.9 0.3 1.6 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 MFS_1 PF07690.11 CCC70888.1 - 7.1e-29 100.6 23.4 7.1e-29 100.6 16.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily BrkDBD PF09607.5 CCC70888.1 - 0.035 13.6 0.2 0.081 12.4 0.1 1.5 1 0 0 1 1 1 0 Brinker DNA-binding domain Sugar_tr PF00083.19 CCC70890.1 - 2.3e-168 560.4 32.5 2.7e-168 560.2 22.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC70890.1 - 6.4e-27 94.1 26.7 1.2e-26 93.3 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 CCC70890.1 - 3.1 6.1 30.1 0.095 11.1 6.3 3.5 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like Aldo_ket_red PF00248.16 CCC70891.1 - 6.7e-66 221.9 0.0 7.6e-66 221.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliD_C PF07195.7 CCC70891.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Hexokinase_2 PF03727.11 CCC70892.1 - 1.5e-94 315.7 0.0 2e-94 315.3 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 CCC70892.1 - 2.5e-82 275.1 0.0 3.4e-82 274.7 0.0 1.2 1 0 0 1 1 1 1 Hexokinase FGGY_N PF00370.16 CCC70892.1 - 0.011 15.0 0.0 0.025 13.8 0.0 1.5 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain GalP_UDP_transf PF01087.17 CCC70893.1 - 0.049 13.6 0.7 0.062 13.3 0.5 1.1 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF1691 PF07950.6 CCC70894.1 - 0.002 18.0 0.0 0.009 15.9 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1691) UPF0370 PF13980.1 CCC70894.1 - 0.096 12.5 0.3 0.58 10.0 0.2 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0370) Integrase_Zn PF02022.14 CCC70894.1 - 6.2 6.3 9.0 0.15 11.5 0.7 2.4 3 0 0 3 3 3 0 Integrase Zinc binding domain Gp_dh_C PF02800.15 CCC70895.1 - 2.3e-71 238.3 0.1 6e-71 236.9 0.1 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 CCC70895.1 - 1.6e-38 132.0 0.2 3.3e-38 131.0 0.0 1.6 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GST_C PF00043.20 CCC70897.1 - 1.6e-08 34.4 0.1 2.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 CCC70897.1 - 0.0019 18.0 0.0 0.0053 16.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCC70897.1 - 0.01 16.0 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCC70897.1 - 0.074 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pox_D5 PF03288.11 CCC70897.1 - 0.11 12.8 0.6 0.26 11.5 0.4 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like FH2 PF02181.18 CCC70899.1 - 2.8e-69 233.7 11.4 2.8e-69 233.7 7.9 2.7 3 0 0 3 3 3 1 Formin Homology 2 Domain SKG6 PF08693.5 CCC70900.1 - 0.00018 20.7 0.6 0.00038 19.6 0.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Sensor PF13796.1 CCC70900.1 - 0.042 13.4 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Putative sensor Coa1 PF08695.5 CCC70901.1 - 1.7e-37 127.4 0.0 2.4e-37 126.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 DUF1748 PF08520.5 CCC70902.1 - 3.5e-31 106.6 0.1 3.9e-31 106.5 0.1 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) UPF0242 PF06785.6 CCC70902.1 - 0.031 12.9 0.0 0.031 12.9 0.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) MOR2-PAG1_N PF14222.1 CCC70903.1 - 7.7e-188 625.6 15.2 7.7e-188 625.6 10.5 2.5 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 CCC70903.1 - 3.4e-95 318.7 7.2 3.7e-95 318.6 2.1 3.1 2 0 0 2 2 2 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 CCC70903.1 - 7.9e-27 93.3 11.8 2.3e-11 42.1 0.7 4.1 2 2 1 3 3 3 3 Cell morphogenesis central region UCH PF00443.24 CCC70904.1 - 2.7e-58 197.1 3.7 2.7e-58 197.1 2.5 2.0 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC70904.1 - 9.5e-30 104.0 4.4 4.1e-29 101.9 3.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DAO PF01266.19 CCC70905.1 - 6.1e-53 179.9 0.0 7.7e-53 179.6 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 CCC70905.1 - 1.5e-11 43.8 2.9 1.1e-10 40.9 2.0 2.0 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 CCC70905.1 - 4.7e-10 39.1 4.8 7.9e-09 35.0 3.3 2.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 CCC70905.1 - 1.2e-05 25.3 0.1 0.00017 21.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCC70905.1 - 3.2e-05 22.9 1.0 0.0013 17.7 0.1 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 CCC70905.1 - 5.8e-05 22.2 0.6 0.0077 15.3 0.0 2.2 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 CCC70905.1 - 8.4e-05 21.2 0.4 0.00016 20.2 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 CCC70905.1 - 0.00046 20.1 0.5 0.0013 18.7 0.2 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CCC70905.1 - 0.0044 16.1 0.0 0.079 11.9 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 CCC70905.1 - 0.0087 15.7 1.6 0.033 13.8 1.1 2.0 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 CCC70905.1 - 0.026 14.9 0.9 0.073 13.4 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 CCC70905.1 - 0.075 13.0 0.3 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding Lycopene_cycl PF05834.7 CCC70905.1 - 0.09 11.6 0.2 0.16 10.8 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pox_Ag35 PF03286.9 CCC70906.1 - 0.0056 16.2 10.4 0.0056 16.2 7.2 1.7 2 0 0 2 2 2 1 Pox virus Ag35 surface protein BUD22 PF09073.5 CCC70906.1 - 0.012 14.6 13.2 0.021 13.9 9.1 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 CCC70906.1 - 0.02 12.8 19.8 0.027 12.4 13.7 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 CCC70906.1 - 0.036 13.9 15.1 0.046 13.6 10.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Radial_spoke PF04712.7 CCC70906.1 - 0.31 9.7 9.9 0.44 9.2 6.9 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein RXT2_N PF08595.6 CCC70906.1 - 0.35 10.6 12.0 0.77 9.5 8.3 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal Cwf_Cwc_15 PF04889.7 CCC70906.1 - 0.41 10.3 19.6 0.68 9.5 13.6 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.3 CCC70906.1 - 0.41 10.5 18.9 0.75 9.6 13.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 Vfa1 PF08432.5 CCC70906.1 - 0.51 10.3 12.8 0.92 9.4 8.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC27 PF09507.5 CCC70906.1 - 0.67 9.1 21.2 0.85 8.7 14.7 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Usp PF00582.21 CCC70906.1 - 1.1 9.4 4.6 29 4.8 0.0 2.4 2 0 0 2 2 2 0 Universal stress protein family NOA36 PF06524.7 CCC70906.1 - 1.1 8.4 12.8 1.9 7.7 8.9 1.2 1 0 0 1 1 1 0 NOA36 protein SPT16 PF08644.6 CCC70906.1 - 1.2 8.9 3.7 1 9.1 1.6 1.6 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) DUF3306 PF11748.3 CCC70906.1 - 2.4 8.8 11.7 0.6 10.7 5.8 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3306) CENP-B_dimeris PF09026.5 CCC70906.1 - 2.6 8.3 20.5 7.4 6.8 14.2 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TRAP_alpha PF03896.11 CCC70906.1 - 3.5 6.5 12.5 6.3 5.7 8.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Paf1 PF03985.8 CCC70906.1 - 6.4 5.4 19.5 9 4.9 13.5 1.2 1 0 0 1 1 1 0 Paf1 PTPA PF03095.10 CCC70907.1 - 1.4e-111 372.5 0.0 1.7e-111 372.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein GspH PF12019.3 CCC70908.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Type II transport protein GspH zf-primase PF09329.6 CCC70909.1 - 7.1e-16 57.5 1.2 1.4e-15 56.5 0.9 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 CCC70909.1 - 0.033 14.0 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 OB-fold nucleic acid binding domain TPR_MLP1_2 PF07926.7 CCC70910.1 - 0.00015 21.4 16.1 0.00015 21.4 11.2 17.6 4 4 11 16 16 16 4 TPR/MLP1/MLP2-like protein Mnd1 PF03962.10 CCC70910.1 - 0.00097 18.8 13.5 0.00097 18.8 9.4 15.5 3 3 10 14 14 14 5 Mnd1 family ubiquitin PF00240.18 CCC70911.1 - 1.3e-34 117.3 0.9 1.7e-34 117.0 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.12 CCC70911.1 - 3.2e-31 106.6 10.7 5.1e-31 106.0 7.4 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.3 CCC70911.1 - 4.7e-20 71.0 0.7 6.5e-20 70.5 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 CCC70911.1 - 7.1e-06 26.1 0.2 2.6e-05 24.4 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 CCC70911.1 - 0.00011 21.9 0.0 0.00015 21.4 0.0 1.2 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 CCC70911.1 - 0.0079 16.0 0.1 0.015 15.1 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 CCC70911.1 - 0.013 15.6 0.1 0.013 15.6 0.0 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Fer2_3 PF13085.1 CCC70911.1 - 0.28 11.0 1.7 1.2 8.9 1.1 2.0 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain HATPase_c PF02518.21 CCC70912.1 - 8.1e-29 99.5 1.3 1.6e-27 95.4 0.9 2.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 CCC70912.1 - 3.5e-27 94.6 0.3 8.4e-27 93.3 0.2 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 CCC70912.1 - 2.4e-10 40.2 0.2 6.2e-10 38.9 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 CCC70912.1 - 0.0013 18.9 7.8 0.098 12.8 0.0 2.9 3 0 0 3 3 3 2 HAMP domain HCO3_cotransp PF00955.16 CCC70913.1 - 0.0064 15.2 0.7 0.011 14.4 0.5 1.3 1 0 0 1 1 1 1 HCO3- transporter family TMEM190 PF15431.1 CCC70913.1 - 0.39 10.6 3.2 0.45 10.4 0.0 2.6 3 1 0 3 3 3 0 Transmembrane protein 190 Pheromone PF08015.6 CCC70913.1 - 5.7 7.8 8.9 47 4.9 1.1 4.0 4 0 0 4 4 4 0 Fungal mating-type pheromone Pantoate_ligase PF02569.10 CCC70914.1 - 4.5e-106 353.6 0.1 5.1e-106 353.5 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase Ndc80_HEC PF03801.8 CCC70915.1 - 2.9e-53 179.5 5.0 2.9e-53 179.5 3.4 2.4 2 0 0 2 2 2 1 HEC/Ndc80p family TMF_DNA_bd PF12329.3 CCC70915.1 - 0.0045 16.7 5.7 0.0045 16.7 3.9 5.4 4 2 1 5 5 5 1 TATA element modulatory factor 1 DNA binding Atg14 PF10186.4 CCC70915.1 - 0.056 12.3 38.6 0.014 14.3 8.4 3.2 2 1 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 CCC70915.1 - 0.067 12.7 45.7 0.024 14.2 12.7 3.7 2 1 2 4 4 4 0 IncA protein Helicase_C_3 PF13625.1 CCC70916.1 - 7.5e-26 90.4 0.0 2e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC70916.1 - 6.1e-14 52.2 0.0 1.5e-13 50.9 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCC70916.1 - 7.8e-12 44.5 0.1 1.3e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCC70916.1 - 1.4e-10 40.8 0.0 3.2e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCC70916.1 - 3.4e-07 29.9 0.0 6.5e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SBP_bac_6 PF13343.1 CCC70916.1 - 0.04 13.2 0.0 0.088 12.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Abhydrolase_6 PF12697.2 CCC70917.1 - 4e-22 79.2 0.0 5.2e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCC70917.1 - 3.5e-05 23.5 0.0 6.1e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC70917.1 - 0.00051 19.6 0.0 0.00079 19.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 CCC70917.1 - 0.0015 17.9 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 CCC70917.1 - 0.078 12.5 0.3 0.18 11.3 0.1 1.6 1 1 0 1 1 1 0 PGAP1-like protein Whi5 PF08528.6 CCC70918.1 - 6e-11 41.6 0.4 1e-10 40.9 0.3 1.4 1 0 0 1 1 1 1 Whi5 like LIM PF00412.17 CCC70920.1 - 6.9e-09 35.6 9.0 6.9e-09 35.6 6.2 2.4 2 0 0 2 2 2 2 LIM domain DUF664 PF04978.7 CCC70920.1 - 0.012 15.8 0.1 0.025 14.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF664) DUF3336 PF11815.3 CCC70921.1 - 6.7e-40 135.9 7.1 3e-39 133.8 4.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 CCC70921.1 - 4.7e-30 105.0 0.0 1e-29 103.9 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_11 PF13414.1 CCC70922.1 - 6.5e-14 51.3 6.2 1.7e-09 37.1 0.6 2.9 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCC70922.1 - 6.5e-11 41.3 6.0 0.00019 20.8 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCC70922.1 - 5.4e-10 38.4 6.3 0.0015 18.3 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCC70922.1 - 6.5e-09 35.6 4.7 0.0042 16.9 1.3 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCC70922.1 - 2.9e-07 29.7 3.7 0.0036 16.9 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCC70922.1 - 4.2e-06 26.1 4.6 0.013 15.2 0.1 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat LRR_4 PF12799.2 CCC70922.1 - 2.8e-05 23.5 16.6 0.064 12.8 0.3 5.4 3 2 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 CCC70922.1 - 0.00018 21.1 0.0 0.00046 19.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCC70922.1 - 0.0018 17.9 0.2 0.0093 15.5 0.1 2.3 2 0 0 2 2 2 1 F-box domain TPR_14 PF13428.1 CCC70922.1 - 0.0028 18.1 0.0 12 6.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 CCC70922.1 - 0.0072 16.9 0.2 8.3 7.2 0.3 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat LRR_7 PF13504.1 CCC70922.1 - 0.014 15.4 9.8 10 6.8 0.0 7.5 7 1 0 7 7 6 0 Leucine rich repeat TPR_9 PF13371.1 CCC70922.1 - 0.017 14.9 0.0 0.55 10.1 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 CCC70922.1 - 0.031 14.4 5.9 0.037 14.1 0.6 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.7 CCC70922.1 - 0.039 13.7 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 CCC70922.1 - 0.075 13.2 1.9 34 4.9 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.13 CCC70922.1 - 0.076 12.9 3.2 1.3 8.9 0.1 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 CCC70922.1 - 0.097 13.1 5.1 2.1 8.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.2 CCC70922.1 - 0.17 11.7 0.1 4.7 7.0 0.1 2.8 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) LRR_6 PF13516.1 CCC70922.1 - 1.8 8.8 23.5 0.32 11.2 0.3 6.7 6 1 1 7 7 5 0 Leucine Rich repeat LRR_8 PF13855.1 CCC70922.1 - 8 6.3 18.5 4 7.2 0.1 5.7 4 2 2 6 6 6 0 Leucine rich repeat Zip PF02535.17 CCC70923.1 - 3.1e-38 131.5 10.4 2.1e-36 125.5 7.2 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3112 PF11309.3 CCC70923.1 - 0.018 14.8 2.6 3 7.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3112) U3_snoRNA_assoc PF08297.6 CCC70924.1 - 4.6e-18 65.2 3.7 4.6e-18 65.2 2.6 3.4 2 1 1 3 3 3 1 U3 snoRNA associated Amino_oxidase PF01593.19 CCC70924.1 - 0.009 15.1 0.7 0.0095 15.0 0.5 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase eIF3_subunit PF08597.5 CCC70924.1 - 0.12 11.9 26.0 0.17 11.3 18.0 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Oxysterol_BP PF01237.13 CCC70924.1 - 0.76 8.1 11.6 0.84 8.0 8.0 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein CAML PF14963.1 CCC70924.1 - 0.77 9.0 10.1 0.092 12.0 3.7 1.8 1 1 1 2 2 2 0 Calcium signal-modulating cyclophilin ligand U79_P34 PF03064.11 CCC70924.1 - 2 7.8 14.7 3.4 7.1 10.2 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 BTV_NS2 PF04514.7 CCC70924.1 - 2 7.1 17.5 2.5 6.9 12.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF1266 PF06889.6 CCC70924.1 - 2.1 8.1 6.3 3.7 7.3 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1266) DUF3153 PF11353.3 CCC70924.1 - 4.4 6.6 8.0 6 6.2 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) DUF2201_N PF13203.1 CCC70924.1 - 8.6 5.4 11.7 11 5.0 8.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Kin17_mid PF10357.4 CCC70925.1 - 2.4e-39 133.8 7.1 4.8e-39 132.9 4.9 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 CCC70925.1 - 9.9e-05 22.3 4.2 9.9e-05 22.3 2.9 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCC70925.1 - 0.00017 21.6 2.5 0.00046 20.2 1.7 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type C1q PF00386.16 CCC70925.1 - 0.004 17.1 0.6 0.004 17.1 0.4 1.7 2 0 0 2 2 2 1 C1q domain zf-C2H2_2 PF12756.2 CCC70925.1 - 0.012 15.6 0.7 0.012 15.6 0.5 2.4 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 CCC70925.1 - 0.13 12.6 3.0 0.29 11.5 2.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger AKAP95 PF04988.7 CCC70925.1 - 0.27 10.9 8.3 0.049 13.4 3.0 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) TFIID_90kDa PF04494.10 CCC70925.1 - 0.48 10.4 5.3 0.19 11.7 1.2 2.1 2 1 0 2 2 2 0 WD40 associated region in TFIID subunit DUF2175 PF09943.4 CCC70925.1 - 3.2 7.8 6.4 1.1 9.3 0.9 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) GTP_EFTU PF00009.22 CCC70926.1 - 9.6e-21 74.0 0.0 1.7e-20 73.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 CCC70926.1 - 0.00015 22.2 0.3 0.00015 22.2 0.2 2.6 4 0 0 4 4 4 1 Miro-like protein MMR_HSR1 PF01926.18 CCC70926.1 - 0.00049 20.0 0.1 0.0015 18.4 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.16 CCC70926.1 - 0.015 14.5 0.1 1.6 7.9 0.0 2.5 2 0 0 2 2 2 0 ADP-ribosylation factor family Thymidylat_synt PF00303.14 CCC70927.1 - 4.3e-117 389.9 0.0 4.8e-117 389.7 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase DIT1_PvcA PF05141.7 CCC70927.1 - 0.12 11.7 0.1 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein Shugoshin_N PF07558.6 CCC70928.1 - 1.8e-11 43.5 10.8 3.8e-11 42.5 5.3 2.8 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region Shugoshin_C PF07557.6 CCC70928.1 - 2.1e-09 36.7 4.9 2.1e-09 36.7 3.4 2.5 2 1 0 2 2 2 1 Shugoshin C terminus CHZ PF09649.5 CCC70928.1 - 0.019 14.1 0.0 0.083 12.1 0.0 2.1 1 0 0 1 1 1 0 Histone chaperone domain CHZ TSC22 PF01166.13 CCC70928.1 - 3.9 7.5 8.7 0.48 10.4 2.0 2.6 2 1 1 3 3 3 0 TSC-22/dip/bun family Brix PF04427.13 CCC70929.1 - 2.5e-37 128.3 1.3 3.3e-37 128.0 0.9 1.1 1 0 0 1 1 1 1 Brix domain RabGAP-TBC PF00566.13 CCC70930.1 - 1.6e-47 161.7 4.5 1.6e-47 161.7 3.1 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Vps5 PF09325.5 CCC70931.1 - 8.4e-59 198.6 7.6 1.5e-58 197.8 5.3 1.4 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CCC70931.1 - 1.3e-20 73.2 0.0 4e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 PX domain FAM180 PF15173.1 CCC70931.1 - 0.045 13.5 0.5 2.1 8.1 0.2 2.4 2 0 0 2 2 2 0 FAM180 family CENP-F_leu_zip PF10473.4 CCC70931.1 - 0.061 13.1 7.7 0.044 13.6 2.7 2.6 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 CCC70931.1 - 0.14 11.9 6.2 0.37 10.5 1.4 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus ING PF12998.2 CCC70931.1 - 0.39 11.0 6.6 0.17 12.2 1.4 2.7 3 0 0 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Alg6_Alg8 PF03155.10 CCC70932.1 - 4.1e-156 520.4 43.1 4.8e-156 520.2 29.8 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Cytochrom_C1 PF02167.10 CCC70934.1 - 1.1e-84 283.5 0.0 1.3e-84 283.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 CCC70934.1 - 0.0008 19.5 0.0 0.0017 18.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 CCC70934.1 - 0.0023 18.7 0.1 0.0067 17.2 0.0 1.9 2 0 0 2 2 2 1 Cytochrome c Zip PF02535.17 CCC70935.1 - 0.0007 18.6 6.7 0.00084 18.4 4.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter SelP_N PF04592.9 CCC70935.1 - 0.28 10.5 13.5 0.43 9.9 9.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region NicO PF03824.11 CCC70935.1 - 5.1 6.3 7.3 6.6 5.9 5.1 1.1 1 0 0 1 1 1 0 High-affinity nickel-transport protein Pkinase PF00069.20 CCC70936.1 - 1.2e-51 175.3 0.0 1.5e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC70936.1 - 9.2e-16 57.6 0.0 1.3e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCC70936.1 - 6.2e-07 29.3 0.1 1.6e-06 28.0 0.1 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 CCC70936.1 - 0.012 15.1 0.0 0.019 14.5 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RepA_C PF04796.7 CCC70937.1 - 0.068 12.7 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 Plasmid encoded RepA protein DUF3644 PF12358.3 CCC70937.1 - 0.25 11.6 2.0 0.58 10.4 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3644) DUF676 PF05057.9 CCC70938.1 - 8.4e-48 162.5 0.1 1.2e-47 162.0 0.1 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 CCC70938.1 - 1.4e-08 34.6 0.0 2.8e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 CCC70938.1 - 0.025 13.6 0.1 0.18 10.8 0.0 2.3 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.20 CCC70938.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.2 CCC70938.1 - 0.062 13.0 0.0 0.21 11.3 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2340 PF10209.4 CCC70939.1 - 2.3e-53 179.5 2.0 2.7e-53 179.2 1.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) MAP65_ASE1 PF03999.7 CCC70940.1 - 3e-76 257.3 50.1 5.1e-76 256.6 34.7 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) YlqD PF11068.3 CCC70940.1 - 9.9 6.2 30.2 1.5 8.8 1.7 4.6 2 1 0 4 4 4 0 YlqD protein SRP1_TIP1 PF00660.12 CCC70941.1 - 7.6e-05 22.4 3.0 0.00014 21.5 1.3 2.0 2 0 0 2 2 2 1 Seripauperin and TIP1 family Flavoprotein PF02441.14 CCC70942.1 - 6.2e-41 139.0 0.1 1.2e-40 138.1 0.1 1.5 1 0 0 1 1 1 1 Flavoprotein BUD22 PF09073.5 CCC70942.1 - 0.0046 16.1 27.1 0.0081 15.2 18.8 1.5 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 CCC70942.1 - 0.026 12.4 43.4 0.034 12.0 30.1 1.1 1 0 0 1 1 1 0 Nop14-like family DUF1510 PF07423.6 CCC70942.1 - 0.57 9.5 30.8 1.1 8.5 21.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) PPP4R2 PF09184.6 CCC70942.1 - 1.9 7.9 38.5 0.35 10.3 23.2 2.2 2 0 0 2 2 2 0 PPP4R2 Trypan_PARP PF05887.6 CCC70942.1 - 2.3 8.0 18.1 5.9 6.7 12.6 1.6 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC45 PF02724.9 CCC70942.1 - 2.5 6.0 33.0 4.2 5.2 22.9 1.3 1 0 0 1 1 1 0 CDC45-like protein NPR3 PF03666.8 CCC70942.1 - 9.9 4.5 8.4 19 3.6 5.8 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-AN1 PF01428.11 CCC70943.1 - 3.1e-10 39.7 11.0 5e-10 39.0 7.6 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger Transp_Tc5_C PF04236.10 CCC70943.1 - 0.17 12.0 5.3 0.32 11.2 3.7 1.4 1 0 0 1 1 1 0 Tc5 transposase C-terminal domain Nro1 PF12753.2 CCC70944.1 - 4.6e-133 444.0 23.5 5.3e-133 443.8 16.3 1.0 1 0 0 1 1 1 1 Nuclear pore complex subunit Nro1 FAST_1 PF06743.10 CCC70944.1 - 0.00037 20.1 0.2 0.0028 17.3 0.3 2.3 2 0 0 2 2 2 1 FAST kinase-like protein, subdomain 1 TPR_11 PF13414.1 CCC70944.1 - 0.031 13.9 0.6 0.14 11.8 0.2 2.2 2 1 0 2 2 2 0 TPR repeat DUF3698 PF12479.3 CCC70944.1 - 0.089 12.8 1.9 5.7 7.0 0.3 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3698) RTA1 PF04479.8 CCC70945.1 - 8.6e-79 264.1 4.7 1.1e-78 263.8 3.3 1.1 1 0 0 1 1 1 1 RTA1 like protein zf-DHHC PF01529.15 CCC70945.1 - 0.0093 15.3 4.5 0.72 9.2 0.3 2.8 2 1 0 2 2 2 2 DHHC palmitoyltransferase XRN_N PF03159.13 CCC70946.1 - 2.3e-107 357.8 0.1 8e-107 356.0 0.0 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus DEAD PF00270.24 CCC70948.1 - 4.6e-35 120.6 0.4 1.6e-34 118.8 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC70948.1 - 2.6e-26 91.2 0.1 4.7e-26 90.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC70948.1 - 0.00042 20.2 0.0 0.0025 17.7 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 CCC70948.1 - 0.043 13.7 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Helicase C-terminal domain AAA_30 PF13604.1 CCC70948.1 - 0.043 13.3 0.0 0.18 11.3 0.0 2.0 2 1 0 2 2 2 0 AAA domain CMS1 PF14617.1 CCC70948.1 - 0.23 10.4 10.5 5.2 6.0 5.2 2.8 2 1 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Pmp3 PF01679.12 CCC70949.1 - 1e-19 69.9 5.6 1.1e-19 69.8 3.9 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator BTP PF05232.7 CCC70949.1 - 0.15 11.8 1.7 0.18 11.5 1.2 1.1 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family CoxIIa PF08113.6 CCC70949.1 - 0.35 10.6 3.3 0.17 11.6 0.7 1.6 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family DUF1426 PF07234.6 CCC70951.1 - 0.027 14.1 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1426) CUE PF02845.11 CCC70953.1 - 3.7e-11 42.2 0.1 1.2e-10 40.6 0.0 1.9 2 0 0 2 2 2 1 CUE domain Lactamase_B PF00753.22 CCC70954.1 - 2e-19 69.9 0.1 4.5e-19 68.8 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 CCC70954.1 - 7.4e-06 25.6 0.1 1.1e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CCC70954.1 - 0.0091 15.7 0.1 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain CK_II_beta PF01214.13 CCC70955.1 - 7.7e-72 240.6 0.2 9.4e-72 240.3 0.2 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit AAA-ATPase_like PF09820.4 CCC70955.1 - 0.019 14.1 0.3 0.027 13.6 0.2 1.2 1 0 0 1 1 1 0 Predicted AAA-ATPase DUF2652 PF10851.3 CCC70955.1 - 0.049 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) Hira PF07569.6 CCC70956.1 - 2.6e-84 281.8 1.4 2.5e-81 272.0 0.1 3.5 3 0 0 3 3 3 2 TUP1-like enhancer of split WD40 PF00400.27 CCC70956.1 - 0.03 14.1 2.2 5.2 7.1 0.0 3.1 3 0 0 3 3 3 0 WD domain, G-beta repeat FAD_binding_6 PF00970.19 CCC70957.1 - 1.3e-06 28.4 0.0 8e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain SNARE PF05739.14 CCC70958.1 - 4e-18 64.8 4.6 4e-18 64.8 3.2 3.1 3 0 0 3 3 3 1 SNARE domain Syntaxin_2 PF14523.1 CCC70958.1 - 3.6e-16 59.0 9.5 3.6e-16 59.0 6.6 2.7 1 1 2 3 3 3 1 Syntaxin-like protein Peptidase_C6 PF00851.13 CCC70958.1 - 0.054 12.1 20.2 0.0065 15.1 8.7 2.0 1 1 1 2 2 2 0 Helper component proteinase Ferritin_2 PF13668.1 CCC70958.1 - 0.068 13.1 1.1 0.2 11.6 0.8 1.8 1 1 0 1 1 1 0 Ferritin-like domain Vfa1 PF08432.5 CCC70958.1 - 0.17 11.9 9.2 0.34 10.9 6.4 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2077 PF09850.4 CCC70958.1 - 0.33 10.3 0.0 0.33 10.3 0.0 2.5 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2077) Adaptin_binding PF10199.4 CCC70959.1 - 0.087 13.1 0.7 15 5.8 0.0 2.4 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 zf-C3HC4_3 PF13920.1 CCC70961.1 - 2.1e-06 27.2 6.9 2.1e-06 27.2 4.8 3.9 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 CCC70961.1 - 0.037 14.3 2.7 0.037 14.3 1.9 7.2 7 0 0 7 7 7 0 Zinc finger, C2H2 type UNC45-central PF11701.3 CCC70962.1 - 1.1e-24 86.8 1.5 1.1e-24 86.8 1.1 2.9 3 1 0 3 3 3 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 CCC70962.1 - 0.00018 21.7 2.4 1.2 9.4 0.0 4.7 6 0 0 6 6 6 2 HEAT repeats Ank_2 PF12796.2 CCC70963.1 - 1.7e-48 162.9 7.9 1.6e-14 53.9 0.1 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 CCC70963.1 - 1.2e-26 91.1 4.2 7.7e-09 34.9 0.1 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 CCC70963.1 - 2.1e-21 75.8 11.9 8.1e-08 32.5 0.1 5.7 3 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCC70963.1 - 3.8e-19 66.8 6.6 3e-05 23.8 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 CCC70963.1 - 9.2e-19 67.0 1.1 5.2e-06 26.5 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) XPG_N PF00752.12 CCC70964.1 - 4.9e-32 110.2 0.2 7.2e-30 103.2 0.0 3.0 3 0 0 3 3 3 1 XPG N-terminal domain XPG_I PF00867.13 CCC70964.1 - 5e-22 77.7 0.0 1.5e-21 76.2 0.0 1.9 1 0 0 1 1 1 1 XPG I-region TPR_8 PF13181.1 CCC70964.1 - 0.054 13.3 0.2 0.43 10.4 0.0 2.5 2 1 1 3 3 3 0 Tetratricopeptide repeat XPG_I_2 PF12813.2 CCC70964.1 - 0.12 11.8 1.1 0.19 11.2 0.1 1.8 2 0 0 2 2 2 0 XPG domain containing HLH PF00010.21 CCC70965.1 - 2.3e-17 62.3 3.7 1.3e-16 59.9 2.6 2.2 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain PalH PF08733.5 CCC70966.1 - 8.1e-68 228.7 18.6 1.1e-67 228.3 12.9 1.2 1 0 0 1 1 1 1 PalH/RIM21 PGG PF13962.1 CCC70966.1 - 0.0042 16.6 2.4 1.7 8.2 0.1 2.9 2 0 0 2 2 2 2 Domain of unknown function DUF4191 PF13829.1 CCC70966.1 - 0.25 10.4 0.2 0.47 9.5 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) bZIP_1 PF00170.16 CCC70967.1 - 8.5e-10 38.4 12.7 1.7e-09 37.5 8.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 CCC70967.1 - 0.081 13.2 11.6 0.065 13.5 6.8 1.7 2 0 0 2 2 2 0 bZIP Maf transcription factor TFIIA PF03153.8 CCC70967.1 - 2.6 7.8 12.5 3.5 7.4 8.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TPR_11 PF13414.1 CCC70968.1 - 2.9e-56 187.0 28.4 2.3e-16 59.1 0.1 6.3 4 2 2 6 6 6 6 TPR repeat TPR_1 PF00515.23 CCC70968.1 - 2.2e-44 147.2 29.3 4.8e-08 32.2 0.1 9.4 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 CCC70968.1 - 1.6e-37 124.4 26.2 6.2e-06 25.7 0.1 9.4 9 0 0 9 9 9 9 Tetratricopeptide repeat TPR_12 PF13424.1 CCC70968.1 - 2.2e-27 94.7 17.0 3e-10 39.8 1.1 5.7 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCC70968.1 - 2.1e-23 82.4 8.8 0.00039 20.9 0.0 6.7 4 2 2 6 6 6 6 Tetratricopeptide repeat TPR_8 PF13181.1 CCC70968.1 - 5.7e-23 78.9 24.2 0.00048 19.7 0.3 9.3 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCC70968.1 - 2.2e-19 68.1 12.7 0.17 12.5 0.1 10.0 4 3 7 11 11 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 CCC70968.1 - 3e-15 56.2 20.6 9.6e-05 22.6 0.1 7.1 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 CCC70968.1 - 3.8e-15 54.7 12.2 0.0014 18.6 0.0 7.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCC70968.1 - 2.7e-14 51.7 14.5 0.00047 19.7 0.0 8.0 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_9 PF13371.1 CCC70968.1 - 7.6e-10 38.5 0.8 4.3e-05 23.2 0.0 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 CCC70968.1 - 1.8e-05 24.7 17.7 0.35 11.0 0.1 4.7 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 CCC70968.1 - 5.9e-05 22.8 1.2 4.2 7.4 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF3808 PF10300.4 CCC70968.1 - 0.00061 18.4 0.1 0.00061 18.4 0.0 3.0 3 1 0 3 3 3 1 Protein of unknown function (DUF3808) TPR_6 PF13174.1 CCC70968.1 - 0.001 19.4 28.3 0.32 11.5 0.1 8.9 10 0 0 10 10 9 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 CCC70968.1 - 0.0033 16.6 13.8 8.6 5.6 0.0 7.1 7 0 0 7 7 7 0 SHNi-TPR TPR_20 PF14561.1 CCC70968.1 - 0.007 16.4 0.6 0.007 16.4 0.4 4.7 5 1 0 5 5 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCC70968.1 - 0.013 15.3 4.6 24 4.8 0.0 4.7 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF3856 PF12968.2 CCC70968.1 - 0.044 13.6 11.3 2.3 8.0 0.5 4.7 3 2 1 4 4 4 0 Domain of Unknown Function (DUF3856) TPR_3 PF07720.7 CCC70968.1 - 0.61 9.9 5.0 35 4.3 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 CCC70968.1 - 0.62 10.1 4.5 8.1 6.6 0.0 4.8 6 0 0 6 6 5 0 PPR repeat OppC_N PF12911.2 CCC70969.1 - 0.068 12.5 2.5 7.2 6.0 0.1 2.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C BPD_transp_1 PF00528.17 CCC70969.1 - 1.3 8.4 8.2 1.8 8.0 5.2 1.6 1 1 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component SIR2 PF02146.12 CCC70971.1 - 2.5e-35 121.8 0.0 6.3e-22 78.1 0.0 2.5 1 1 1 2 2 2 2 Sir2 family Zn-ribbon_8 PF09723.5 CCC70971.1 - 0.4 10.6 1.9 2.4 8.1 1.6 2.1 1 1 1 2 2 2 0 Zinc ribbon domain DUF2256 PF10013.4 CCC70971.1 - 0.44 10.3 3.1 0.45 10.3 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) Cpn10 PF00166.16 CCC70973.1 - 6.5e-27 93.3 0.4 7.3e-27 93.1 0.3 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF2611 PF11022.3 CCC70974.1 - 3.8e-14 52.5 0.0 4.4e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) LIN37 PF15306.1 CCC70975.1 - 1.8 8.5 8.5 0.1 12.5 0.3 2.4 2 0 0 2 2 2 0 LIN37 Acetyltransf_1 PF00583.19 CCC70977.1 - 3.8e-16 58.8 0.0 5.7e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 CCC70977.1 - 1.6e-05 24.9 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 CCC70977.1 - 2.8e-05 24.1 0.0 4.8e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 CCC70977.1 - 4.1e-05 23.2 0.0 7.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 CCC70977.1 - 0.0031 17.7 0.0 0.0041 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 CCC70977.1 - 0.0034 17.2 0.0 0.005 16.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 CCC70977.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 CCC70977.1 - 0.068 13.0 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Metallophos_2 PF12850.2 CCC70978.1 - 5.5e-11 42.5 0.0 9.4e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GAGA_bind PF06217.7 CCC70978.1 - 0.049 13.5 5.8 0.071 13.0 4.0 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family XAP5 PF04921.9 CCC70978.1 - 0.24 10.9 8.9 0.35 10.3 6.2 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator CDC45 PF02724.9 CCC70978.1 - 0.32 8.9 12.1 0.4 8.6 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Podoplanin PF05808.6 CCC70978.1 - 0.59 9.6 5.4 1.1 8.8 3.8 1.4 1 0 0 1 1 1 0 Podoplanin Hid1 PF12722.2 CCC70978.1 - 0.67 7.5 12.1 0.88 7.1 8.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 CCC70978.1 - 7.7 4.0 11.4 10 3.7 7.9 1.0 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 CCC70978.1 - 9.7 5.9 11.1 15 5.3 7.7 1.3 1 0 0 1 1 1 0 DDHD domain tRNA-synt_2b PF00587.20 CCC70979.1 - 6.1e-20 71.5 0.0 1e-19 70.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 CCC70979.1 - 6.4e-06 26.1 3.7 1.3e-05 25.1 2.6 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Mnd1 PF03962.10 CCC70979.1 - 0.011 15.4 1.1 0.016 14.8 0.8 1.2 1 0 0 1 1 1 0 Mnd1 family DUF2031 PF09592.5 CCC70979.1 - 0.023 13.8 0.9 0.038 13.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) Ribosomal_L27e PF01777.13 CCC70980.1 - 1.4e-36 124.5 7.0 1.8e-36 124.0 4.8 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 CCC70980.1 - 0.00025 20.6 1.5 0.0005 19.6 1.0 1.6 1 0 0 1 1 1 1 KOW motif DUF1512 PF07431.7 CCC70980.1 - 0.093 11.4 0.2 0.16 10.7 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1512) DAO PF01266.19 CCC70981.1 - 3.8e-62 210.2 0.0 4.4e-61 206.7 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 CCC70981.1 - 7.9e-06 25.8 0.0 3.1e-05 23.8 0.0 2.0 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 CCC70981.1 - 0.0054 15.8 0.0 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Saccharop_dh PF03435.13 CCC70981.1 - 0.0084 15.1 0.1 0.016 14.1 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox PF00070.22 CCC70981.1 - 0.0091 16.3 0.1 0.024 15.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 CCC70981.1 - 0.0096 14.5 0.3 0.27 9.8 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 CCC70981.1 - 0.016 14.9 0.1 0.05 13.3 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 CCC70981.1 - 0.034 14.2 0.0 0.12 12.4 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Serglycin PF04360.7 CCC70981.1 - 0.044 13.5 2.8 0.078 12.7 1.9 1.3 1 0 0 1 1 1 0 Serglycin SR-25 PF10500.4 CCC70981.1 - 0.18 11.2 11.3 0.3 10.5 7.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein AF-4 PF05110.8 CCC70981.1 - 1.9 6.2 16.0 2.7 5.7 11.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sod_Fe_C PF02777.13 CCC70982.1 - 9.3e-37 125.1 0.3 1.7e-36 124.2 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 CCC70982.1 - 1.1e-25 89.7 0.4 2.2e-25 88.6 0.3 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HHH_2 PF12826.2 CCC70982.1 - 0.052 13.4 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Helix-hairpin-helix motif p450 PF00067.17 CCC70983.1 - 2.1e-101 339.7 0.1 2.4e-101 339.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3666 PF12408.3 CCC70983.1 - 0.28 10.3 2.4 7.3 5.7 0.0 2.8 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase Flo11 PF10182.4 CCC70984.1 - 8.1e-46 155.3 1.0 1e-45 155.0 0.7 1.1 1 0 0 1 1 1 1 Flo11 domain DUF605 PF04652.11 CCC70984.1 - 0.23 10.8 37.2 0.39 10.0 25.8 1.4 1 0 0 1 1 1 0 Vta1 like LCAT PF02450.10 CCC70985.1 - 2.5e-131 438.2 0.3 3.2e-131 437.8 0.2 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 CCC70985.1 - 0.00018 20.8 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 2) DUF1749 PF08538.5 CCC70985.1 - 0.001 18.0 0.0 0.002 17.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.2 CCC70985.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC70985.1 - 0.0046 16.5 0.0 0.13 11.7 0.0 2.7 3 0 0 3 3 3 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 CCC70985.1 - 0.019 14.5 0.0 0.064 12.8 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_6 PF12697.2 CCC70985.1 - 0.02 14.7 0.0 0.037 13.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.7 CCC70985.1 - 0.064 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PBP1_TM PF14812.1 CCC70985.1 - 0.092 13.0 0.8 0.21 11.9 0.6 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Autophagy_N PF03986.8 CCC70986.1 - 8.7e-42 142.3 0.2 8.7e-42 142.3 0.1 1.9 2 0 0 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 CCC70986.1 - 2.5e-22 78.8 0.5 1e-21 76.8 0.1 2.2 2 0 0 2 2 2 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 CCC70986.1 - 1.5e-15 55.9 2.0 3.1e-15 54.9 1.4 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal VHS PF00790.14 CCC70987.1 - 1.2e-37 128.7 0.2 1.2e-37 128.7 0.1 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 CCC70987.1 - 1.2e-19 69.9 4.5 2.8e-19 68.7 3.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 CCC70987.1 - 1.5e-06 27.2 8.0 0.00072 18.9 0.6 3.2 2 0 0 2 2 2 2 Ubiquitin interaction motif DUF892 PF05974.7 CCC70987.1 - 0.0047 16.7 2.4 0.014 15.1 0.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF892) zf-UDP PF14569.1 CCC70987.1 - 1.2 8.9 4.0 1.8 8.3 2.2 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger XPA_N PF01286.13 CCC70987.1 - 4.1 7.1 10.0 27 4.5 0.7 3.5 3 0 0 3 3 3 0 XPA protein N-terminal Cyclin_N PF00134.18 CCC70988.1 - 5e-34 116.6 0.0 1.1e-33 115.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain BBP1_C PF15272.1 CCC70989.1 - 4.7e-58 195.9 26.8 9.9e-58 194.9 18.6 1.5 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal BBP1_N PF15271.1 CCC70989.1 - 2.9e-38 131.4 5.8 2.9e-38 131.4 4.0 2.7 2 1 0 2 2 2 1 Spindle pole body component BBP1, Mps2-binding protein OEP PF02321.13 CCC70989.1 - 0.74 9.3 17.9 0.33 10.4 10.6 1.7 1 1 0 1 1 1 0 Outer membrane efflux protein DUF342 PF03961.8 CCC70989.1 - 2.4 6.4 13.5 0.3 9.4 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) TBPIP PF07106.8 CCC70989.1 - 5.6 6.4 19.3 0.23 10.9 5.7 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SAGA-Tad1 PF12767.2 CCC70990.1 - 1.1e-70 238.1 0.1 1.7e-70 237.6 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 CCC70990.1 - 0.00058 19.2 0.0 0.00095 18.5 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family Cob_adeno_trans PF01923.13 CCC70991.1 - 1 9.1 18.1 0.13 12.0 0.5 3.5 1 1 2 3 3 3 0 Cobalamin adenosyltransferase NPV_P10 PF05531.7 CCC70991.1 - 5.7 7.2 16.0 0.34 11.2 0.3 4.2 3 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Fer2 PF00111.22 CCC70992.1 - 4.5e-14 51.9 0.7 6.2e-14 51.5 0.5 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Glyco_hydro_63 PF03200.11 CCC70993.1 - 0.0023 15.8 0.4 0.0023 15.8 0.3 5.1 5 1 0 5 5 5 3 Mannosyl oligosaccharide glucosidase Ribosomal_L36e PF01158.13 CCC70995.1 - 2.2e-37 126.9 4.7 2.4e-37 126.8 3.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e RabGAP-TBC PF00566.13 CCC70996.1 - 3.7e-51 173.6 0.5 3.7e-51 173.6 0.3 3.2 3 0 0 3 3 3 2 Rab-GTPase-TBC domain WD40_alt PF14077.1 CCC70996.1 - 0.13 11.8 3.8 0.61 9.7 2.6 2.2 1 0 0 1 1 1 0 Alternative WD40 repeat motif Fungal_trans PF04082.13 CCC70997.1 - 2.6e-31 108.4 10.6 4.5e-31 107.6 4.7 2.9 3 0 0 3 3 3 1 Fungal specific transcription factor domain Gal4_dimer PF03902.8 CCC70997.1 - 3.7e-08 33.1 0.8 7.8e-07 28.9 0.0 2.5 2 0 0 2 2 2 1 Gal4-like dimerisation domain Zn_clus PF00172.13 CCC70997.1 - 8.8e-08 31.9 18.9 1.6e-07 31.1 13.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ISN1 PF06437.6 CCC70997.1 - 0.031 13.0 0.1 0.06 12.0 0.0 1.4 1 0 0 1 1 1 0 IMP-specific 5'-nucleotidase BRCA2 PF00634.13 CCC70997.1 - 0.036 13.3 0.0 0.075 12.3 0.0 1.5 1 0 0 1 1 1 0 BRCA2 repeat RQC PF09382.5 CCC70998.1 - 1.1e-24 86.1 0.3 2.8e-24 84.8 0.2 1.7 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 CCC70998.1 - 1.6e-22 79.8 0.0 4.5e-22 78.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC70998.1 - 9.5e-21 73.4 0.1 1.3e-18 66.6 0.0 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain WD40 PF00400.27 CCC70999.1 - 2e-22 78.1 11.3 1.3e-07 31.2 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat Rhomboid PF01694.17 CCC71000.1 - 1.5e-16 60.7 16.5 1.5e-16 60.7 11.4 1.4 2 0 0 2 2 2 1 Rhomboid family Antimicrobial12 PF08107.6 CCC71000.1 - 0.12 11.9 1.0 0.37 10.3 0.7 1.8 1 0 0 1 1 1 0 Pleurocidin family DUF2075 PF09848.4 CCC71001.1 - 3.7e-101 338.6 0.0 4.9e-101 338.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 CCC71001.1 - 1.4e-10 41.4 0.0 3.3e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 CCC71001.1 - 4.8e-05 23.5 0.0 0.00011 22.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 CCC71001.1 - 5.2e-05 23.1 0.3 0.21 11.4 0.0 2.5 1 1 1 2 2 2 2 Type III restriction enzyme, res subunit AAA_16 PF13191.1 CCC71001.1 - 0.00017 21.6 0.0 0.00029 20.8 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain PIF1 PF05970.9 CCC71001.1 - 0.0023 16.9 0.0 0.0031 16.5 0.0 1.3 1 0 0 1 1 1 1 PIF1-like helicase AAA_14 PF13173.1 CCC71001.1 - 0.005 16.7 0.6 0.017 15.0 0.4 1.9 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 CCC71001.1 - 0.012 15.2 0.4 0.13 11.9 0.1 2.3 1 1 1 2 2 2 0 Bacterial dnaA protein SNF2_N PF00176.18 CCC71001.1 - 0.013 14.3 0.2 0.12 11.1 0.0 2.1 1 1 1 2 2 2 0 SNF2 family N-terminal domain AAA_30 PF13604.1 CCC71001.1 - 0.02 14.4 0.0 0.13 11.7 0.0 2.2 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.4 CCC71001.1 - 0.023 13.6 0.0 0.052 12.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Arch_ATPase PF01637.13 CCC71001.1 - 0.026 14.2 0.2 0.17 11.5 0.2 2.3 1 1 0 1 1 1 0 Archaeal ATPase DUF815 PF05673.8 CCC71001.1 - 0.034 13.0 0.0 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 CCC71001.1 - 0.034 14.3 0.2 0.26 11.4 0.0 2.6 2 1 1 3 3 3 0 RNA helicase T2SE PF00437.15 CCC71001.1 - 0.051 12.4 0.1 0.082 11.7 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Zds_C PF08632.5 CCC71001.1 - 0.053 12.9 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Activator of mitotic machinery Cdc14 phosphatase activation C-term NACHT PF05729.7 CCC71001.1 - 0.06 13.0 0.1 0.16 11.6 0.0 1.8 1 1 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 CCC71001.1 - 0.11 12.4 0.5 0.25 11.2 0.3 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase UAA PF08449.6 CCC71002.1 - 3.2e-77 259.4 19.2 3.7e-77 259.2 13.3 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 CCC71002.1 - 1.1e-08 34.8 9.5 1.1e-08 34.8 6.6 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 CCC71002.1 - 2.4e-08 33.4 11.1 1.6e-06 27.4 2.8 2.2 1 1 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 CCC71002.1 - 7e-06 26.0 9.6 7e-06 26.0 6.7 3.5 4 1 0 4 4 4 2 EamA-like transporter family DUF1664 PF07889.7 CCC71002.1 - 0.086 12.6 2.1 0.094 12.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) EmrE PF13536.1 CCC71002.1 - 0.093 12.9 24.4 0.31 11.2 7.6 3.6 3 1 1 4 4 4 0 Multidrug resistance efflux transporter L31 PF09784.4 CCC71003.1 - 0.29 11.2 4.9 0.17 11.9 0.2 3.0 3 0 0 3 3 3 0 Mitochondrial ribosomal protein L31 RasGAP_C PF03836.10 CCC71004.1 - 1e-27 96.5 6.3 3.6e-27 94.7 4.4 2.0 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 CCC71004.1 - 3.3e-16 59.5 3.6 3.3e-16 59.5 2.5 2.9 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 CCC71004.1 - 6.2e-10 39.0 0.2 6.8e-09 35.7 0.0 2.9 2 0 0 2 2 2 1 Calponin homology (CH) domain NPV_P10 PF05531.7 CCC71004.1 - 0.0057 16.8 3.8 0.012 15.8 1.3 2.7 2 0 0 2 2 2 1 Nucleopolyhedrovirus P10 protein IQ PF00612.22 CCC71004.1 - 7.5 6.4 22.3 0.11 12.1 0.6 6.3 6 0 0 6 6 6 0 IQ calmodulin-binding motif TBCC PF07986.7 CCC71005.1 - 0.00021 20.7 1.3 0.001 18.4 0.9 2.1 1 1 0 1 1 1 1 Tubulin binding cofactor C Coat_X PF07552.6 CCC71005.1 - 0.0014 18.3 0.0 0.0046 16.7 0.0 1.9 1 0 0 1 1 1 1 Spore Coat Protein X and V domain HR1 PF02185.11 CCC71005.1 - 0.74 9.5 5.0 24 4.7 0.0 2.9 2 1 0 2 2 2 0 Hr1 repeat Ank_2 PF12796.2 CCC71006.1 - 2.9e-24 85.2 0.2 1.2e-15 57.6 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCC71006.1 - 3.5e-16 58.0 0.2 2e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 CCC71006.1 - 4.6e-15 55.2 1.1 1.3e-08 34.7 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 CCC71006.1 - 1.3e-13 51.0 0.0 4.6e-07 30.1 0.1 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCC71006.1 - 1.6e-12 46.3 0.1 4.7e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat PqqD PF05402.7 CCC71006.1 - 0.014 15.4 0.5 3.1 7.8 0.0 2.6 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) eIF-5_eIF-2B PF01873.12 CCC71007.1 - 6.6e-45 151.8 0.1 1.1e-44 151.1 0.1 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 IF2_N PF04760.10 CCC71007.1 - 0.012 15.2 0.0 0.093 12.3 0.0 2.5 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region TF_Zn_Ribbon PF08271.7 CCC71007.1 - 0.094 12.0 0.2 0.18 11.1 0.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding Pkinase PF00069.20 CCC71008.1 - 2.3e-22 79.4 0.0 1.1e-21 77.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71008.1 - 1.5e-10 40.5 0.0 5.6e-09 35.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCC71008.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Kinase-like TIP49 PF06068.8 CCC71009.1 - 8.8e-178 591.0 2.4 1.1e-177 590.7 1.7 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 CCC71009.1 - 6.4e-08 32.8 2.0 7.2e-05 23.0 0.0 2.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCC71009.1 - 2.7e-06 26.5 3.3 0.0025 16.8 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 CCC71009.1 - 1.1e-05 24.4 0.6 2.2e-05 23.4 0.1 1.7 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 CCC71009.1 - 2.6e-05 24.3 0.2 0.058 13.5 0.0 2.6 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 CCC71009.1 - 7e-05 22.8 0.1 0.00069 19.6 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 CCC71009.1 - 0.00078 19.3 0.4 1.9 8.4 0.0 3.2 4 0 0 4 4 4 2 AAA domain AAA_25 PF13481.1 CCC71009.1 - 0.0063 15.9 1.0 0.018 14.4 0.1 2.0 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 CCC71009.1 - 0.014 14.5 0.8 0.17 11.0 0.2 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 CCC71009.1 - 0.016 15.1 0.1 0.056 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 CCC71009.1 - 0.018 14.8 0.4 1.7 8.3 0.0 2.9 2 2 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 CCC71009.1 - 0.032 13.9 0.2 0.067 12.9 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain Sipho_tail PF05709.6 CCC71009.1 - 0.052 12.6 0.1 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 Phage tail protein ATP-synt_C PF00137.16 CCC71010.1 - 6.3e-28 96.4 26.4 3.8e-15 55.5 2.8 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Polysacc_synt_3 PF13440.1 CCC71010.1 - 0.014 14.8 1.2 0.014 14.8 0.9 1.9 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein Mis14 PF08641.7 CCC71011.1 - 1.1e-30 106.5 4.8 1.1e-30 106.5 3.3 1.5 2 0 0 2 2 2 1 Kinetochore protein Mis14 like APP_E2 PF12925.2 CCC71011.1 - 0.045 13.3 0.2 0.078 12.5 0.2 1.4 1 0 0 1 1 1 0 E2 domain of amyloid precursor protein HTH_Mga PF08280.6 CCC71011.1 - 0.09 12.5 0.0 0.26 11.0 0.0 1.7 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain GreA_GreB_N PF03449.10 CCC71011.1 - 0.11 12.5 0.5 0.11 12.5 0.4 2.2 3 0 0 3 3 3 0 Transcription elongation factor, N-terminal Fib_alpha PF08702.5 CCC71011.1 - 1.5 8.9 4.5 1.8 8.6 0.5 2.6 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family SNARE PF05739.14 CCC71012.1 - 3e-16 58.8 9.4 1.2e-15 56.9 6.5 2.1 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 CCC71012.1 - 4.3e-05 23.6 15.9 0.00011 22.2 3.0 2.4 2 0 0 2 2 2 2 Syntaxin Synaptobrevin PF00957.16 CCC71012.1 - 8.5e-05 22.0 2.1 8.5e-05 22.0 1.4 2.5 2 1 1 3 3 3 1 Synaptobrevin Rifin_STEVOR PF02009.11 CCC71012.1 - 0.0052 16.4 3.2 0.0052 16.4 2.2 1.4 1 1 0 1 1 1 1 Rifin/stevor family T2SF PF00482.18 CCC71012.1 - 0.065 13.1 2.8 0.18 11.7 1.9 1.7 1 1 0 1 1 1 0 Type II secretion system (T2SS), protein F Lsr2 PF11774.3 CCC71012.1 - 0.092 12.6 3.1 0.57 10.1 0.3 2.6 2 1 0 2 2 2 0 Lsr2 Hemerythrin PF01814.18 CCC71012.1 - 0.13 12.4 3.0 2.9 8.0 0.3 2.2 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain DUF3753 PF12575.3 CCC71012.1 - 0.18 11.6 2.7 1.2 8.9 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) DUF2562 PF10814.3 CCC71012.1 - 0.29 11.0 2.9 0.42 10.5 1.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2562) BLOC1_2 PF10046.4 CCC71012.1 - 0.52 10.4 12.6 1.9 8.6 0.1 3.3 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Hsk3 PF08227.6 CCC71012.1 - 1.1 9.5 5.0 30 4.9 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Hsk3 like DUF1664 PF07889.7 CCC71012.1 - 1.1 9.0 12.1 1.1 9.1 2.6 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) DUF2116 PF09889.4 CCC71012.1 - 1.5 8.6 4.1 0.84 9.4 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Baculo_PEP_C PF04513.7 CCC71012.1 - 1.9 8.3 14.7 0.56 10.0 1.8 2.5 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF883 PF05957.8 CCC71012.1 - 4.6 7.7 11.7 1.7 9.0 0.2 3.0 3 1 1 4 4 3 0 Bacterial protein of unknown function (DUF883) DUF755 PF05501.6 CCC71012.1 - 7.8 6.5 13.7 30 4.6 1.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF755) ketoacyl-synt PF00109.21 CCC71013.1 - 9.4e-19 67.8 0.0 1.9e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACPS PF01648.15 CCC71013.1 - 2.9e-17 62.5 0.0 7e-17 61.2 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 CCC71013.1 - 2.4e-11 43.5 0.4 5.6e-11 42.3 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain zf-H2C2_2 PF13465.1 CCC71014.1 - 2.2e-10 40.3 1.7 2.2e-10 40.3 1.2 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 CCC71014.1 - 3e-10 39.8 9.2 4.8e-05 23.4 1.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC71014.1 - 2.1e-09 37.0 7.7 0.0004 20.4 0.4 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCC71014.1 - 0.002 17.9 1.8 0.0021 17.9 0.1 1.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-met PF12874.2 CCC71014.1 - 0.01 16.0 3.3 0.043 14.0 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type BolA PF01722.13 CCC71014.1 - 0.24 11.3 2.1 1.1 9.3 0.6 2.3 2 0 0 2 2 2 0 BolA-like protein gag_pre-integrs PF13976.1 CCC71014.1 - 0.7 9.5 3.5 0.78 9.4 0.4 2.6 2 0 0 2 2 2 0 GAG-pre-integrase domain mRNA_triPase PF02940.10 CCC71015.1 - 2.7e-59 200.5 0.1 5.5e-59 199.4 0.1 1.5 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Glycos_transf_2 PF00535.21 CCC71016.1 - 4.8e-24 84.9 0.0 9.6e-24 83.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 CCC71016.1 - 9.3e-07 28.8 0.0 1.9e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 CCC71016.1 - 3.4e-05 23.0 0.0 4.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 CCC71016.1 - 0.0019 18.5 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Globin PF00042.17 CCC71017.1 - 0.011 16.0 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Globin DUF917 PF06032.7 CCC71018.1 - 0.2 10.1 0.0 0.41 9.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF917) EXOSC1 PF10447.4 CCC71019.1 - 1.1e-33 115.0 0.1 2.4e-33 113.9 0.0 1.6 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 Gemin7 PF11095.3 CCC71019.1 - 0.025 14.2 0.0 0.52 10.0 0.0 2.3 2 0 0 2 2 2 0 Gem-associated protein 7 (Gemin7) PI3K_1B_p101 PF10486.4 CCC71019.1 - 0.73 7.3 3.0 0.98 6.9 2.0 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CRAL_TRIO PF00650.15 CCC71020.1 - 1.9e-38 131.4 0.0 3.3e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCC71020.1 - 2.5e-11 43.5 0.3 8.9e-11 41.7 0.2 2.1 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain Elongin_A PF06881.6 CCC71021.1 - 3.5e-19 69.2 9.4 4.5e-17 62.4 0.3 2.4 1 1 1 2 2 2 2 RNA polymerase II transcription factor SIII (Elongin) subunit A Totivirus_coat PF05518.6 CCC71021.1 - 0.14 9.9 5.4 0.21 9.3 3.8 1.2 1 0 0 1 1 1 0 Totivirus coat protein GST_C PF00043.20 CCC71022.1 - 3.2e-22 78.3 0.0 7.8e-22 77.0 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCC71022.1 - 2.1e-16 59.8 0.0 4.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCC71022.1 - 1.1e-09 38.0 0.0 2.6e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 CCC71022.1 - 3.6e-09 36.6 0.0 7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCC71022.1 - 0.00019 21.2 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LMBR1 PF04791.11 CCC71022.1 - 0.0081 14.7 0.8 0.0082 14.7 0.6 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Y_phosphatase3 PF13350.1 CCC71022.1 - 0.043 14.0 0.1 0.073 13.3 0.1 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family GST_C_3 PF14497.1 CCC71022.1 - 0.052 14.0 1.1 0.077 13.4 0.0 1.9 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Pex14_N PF04695.8 CCC71022.1 - 0.059 13.4 13.6 0.11 12.4 9.4 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Rb_C PF08934.5 CCC71022.1 - 0.5 9.9 8.3 0.82 9.2 5.8 1.2 1 0 0 1 1 1 0 Rb C-terminal domain Suf PF05843.9 CCC71022.1 - 0.83 9.3 14.9 1.3 8.7 10.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CPSF100_C PF13299.1 CCC71022.1 - 2.3 8.4 10.2 4.1 7.5 7.1 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Macoilin PF09726.4 CCC71022.1 - 3.9 5.6 14.8 5.6 5.1 10.3 1.1 1 0 0 1 1 1 0 Transmembrane protein DnaJ PF00226.26 CCC71023.1 - 1.2e-24 85.8 0.2 1.2e-24 85.8 0.1 2.8 3 0 0 3 3 3 1 DnaJ domain zf-C2H2_2 PF12756.2 CCC71023.1 - 4.5e-09 36.3 2.6 0.00023 21.1 0.3 3.5 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 CCC71023.1 - 4.8e-08 32.9 4.7 4.8e-08 32.9 3.3 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CCC71023.1 - 0.00027 21.1 7.5 0.034 14.4 1.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 CCC71023.1 - 0.00031 20.8 3.0 0.00031 20.8 2.1 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type AKAP95 PF04988.7 CCC71023.1 - 0.0005 19.8 1.3 0.0005 19.8 0.9 3.0 3 1 0 3 3 3 1 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 CCC71023.1 - 0.0011 19.1 3.9 0.2 12.0 0.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCC71023.1 - 0.0024 17.7 5.0 0.51 10.3 0.2 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger SID PF11778.3 CCC71024.1 - 4.2e-28 97.9 0.4 4.2e-28 97.9 0.3 2.4 3 0 0 3 3 3 1 Septation initiation Spc7 PF08317.6 CCC71024.1 - 0.014 14.0 39.1 0.029 13.0 9.0 2.6 2 0 0 2 2 2 0 Spc7 kinetochore protein WEMBL PF05701.6 CCC71024.1 - 0.16 10.4 33.8 0.036 12.5 6.7 3.0 2 1 1 3 3 3 0 Weak chloroplast movement under blue light HOOK PF05622.7 CCC71024.1 - 0.2 9.4 35.6 0.056 11.2 12.8 2.1 2 0 0 2 2 2 0 HOOK protein DUF1664 PF07889.7 CCC71024.1 - 0.21 11.3 23.9 0.23 11.2 2.6 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) MCPsignal PF00015.16 CCC71024.1 - 0.42 10.1 8.1 0.034 13.6 1.8 1.9 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain KLRAQ PF10205.4 CCC71024.1 - 0.5 10.4 24.8 0.33 10.9 0.6 3.5 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein OmpH PF03938.9 CCC71024.1 - 0.65 9.9 19.5 2.4 8.0 6.7 2.5 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.4 CCC71024.1 - 0.75 8.6 28.8 0.71 8.7 11.7 2.9 2 1 1 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 IFT57 PF10498.4 CCC71024.1 - 0.82 8.3 30.3 0.31 9.7 9.0 2.4 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF2203 PF09969.4 CCC71024.1 - 1.1 9.4 12.8 0.33 11.1 3.7 2.8 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2968 PF11180.3 CCC71024.1 - 3.9 6.7 18.5 6.8 6.0 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) G-patch PF01585.18 CCC71025.1 - 3.2e-11 42.8 2.3 6.1e-11 41.9 1.6 1.5 1 0 0 1 1 1 1 G-patch domain Peptidase_C54 PF03416.14 CCC71026.1 - 1.2e-88 296.8 0.0 1.7e-88 296.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C54 Ssu72 PF04722.8 CCC71027.1 - 9.4e-89 295.9 0.0 1.1e-88 295.7 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein POP1 PF06978.6 CCC71029.1 - 6.1e-65 218.3 13.0 6.1e-65 218.3 9.0 2.1 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 CCC71029.1 - 6.6e-31 106.0 1.1 1.6e-30 104.8 0.8 1.7 1 0 0 1 1 1 1 POPLD (NUC188) domain Adenylsucc_synt PF00709.16 CCC71030.1 - 2.1e-163 543.8 0.0 2.4e-163 543.7 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Glyco_transf_22 PF03901.12 CCC71031.1 - 5.9e-90 302.2 37.5 1e-89 301.4 26.0 1.3 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family MgsA_C PF12002.3 CCC71032.1 - 2.5e-53 180.1 0.1 7e-53 178.7 0.1 1.7 2 0 0 2 2 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 CCC71032.1 - 2.6e-15 56.7 0.0 7.8e-15 55.2 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCC71032.1 - 1.5e-13 50.3 0.0 5e-13 48.6 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCC71032.1 - 1.5e-07 31.5 0.1 0.00058 19.9 0.0 2.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.1 CCC71032.1 - 2.3e-07 30.7 0.0 5.7e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 CCC71032.1 - 2.5e-06 27.2 0.0 6.3e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCC71032.1 - 1.1e-05 25.6 0.8 0.0012 18.9 0.3 2.9 2 1 0 2 2 1 1 AAA domain Sigma54_activat PF00158.21 CCC71032.1 - 1.4e-05 24.6 0.0 7.6e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 CCC71032.1 - 5.9e-05 22.3 0.2 0.35 9.9 0.0 2.3 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 CCC71032.1 - 0.0014 18.0 0.0 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_17 PF13207.1 CCC71032.1 - 0.0018 19.1 0.0 0.0058 17.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 CCC71032.1 - 0.0029 17.8 0.0 0.0071 16.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta2 PF13177.1 CCC71032.1 - 0.0045 16.6 0.0 0.097 12.3 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_2 PF07724.9 CCC71032.1 - 0.0067 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 CCC71032.1 - 0.012 15.7 0.1 0.046 13.8 0.0 2.1 2 0 0 2 2 1 0 RNA helicase AAA_10 PF12846.2 CCC71032.1 - 0.013 14.9 0.8 1 8.7 0.0 2.7 2 1 1 3 3 3 0 AAA-like domain MMR_HSR1 PF01926.18 CCC71032.1 - 0.022 14.7 0.0 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.1 CCC71032.1 - 0.025 14.1 0.0 0.051 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 CCC71032.1 - 0.044 13.8 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 CCC71032.1 - 0.047 13.9 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.8 CCC71032.1 - 0.072 12.0 0.0 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ResIII PF04851.10 CCC71032.1 - 0.072 12.9 0.2 1.1 8.9 0.0 2.2 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_3 PF07726.6 CCC71032.1 - 0.11 12.1 0.0 0.62 9.6 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Hpt PF01627.18 CCC71033.1 - 6.4e-12 45.3 0.0 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Hpt domain Metallophos PF00149.23 CCC71034.1 - 5.4e-10 39.0 0.9 6.4e-09 35.4 0.0 2.5 1 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCC71034.1 - 3e-06 27.1 0.0 4.2e-06 26.6 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos_3 PF14582.1 CCC71034.1 - 0.064 12.4 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Rap1-DNA-bind PF09197.5 CCC71035.1 - 6.5e-43 145.5 7.2 3.1e-39 133.7 0.1 3.7 3 0 0 3 3 3 2 Rap1, DNA-binding Rap1_C PF11626.3 CCC71035.1 - 8.8e-23 80.0 0.0 4.2e-22 77.8 0.0 2.3 1 0 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 CCC71035.1 - 4.3e-08 32.8 0.3 0.00015 21.5 0.0 3.0 3 0 0 3 3 3 2 Rap1 Myb domain Myb_DNA-binding PF00249.26 CCC71035.1 - 6.1e-08 32.6 0.0 7.9e-06 25.8 0.0 3.1 3 0 0 3 3 3 1 Myb-like DNA-binding domain Pox_D2 PF04701.8 CCC71035.1 - 0.0042 17.0 0.1 0.016 15.2 0.0 2.0 1 1 0 1 1 1 1 Pox virus D2 protein Myb_DNA-bind_6 PF13921.1 CCC71035.1 - 0.0077 16.3 1.4 0.87 9.7 0.0 3.6 4 0 0 4 4 4 1 Myb-like DNA-binding domain LIM_bind PF01803.11 CCC71036.1 - 1.5e-32 112.6 2.4 2.2e-32 112.0 1.6 1.3 1 0 0 1 1 1 1 LIM-domain binding protein DUF1204 PF06721.6 CCC71036.1 - 0.1 11.8 3.8 0.074 12.2 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1204) DUF812 PF05667.6 CCC71037.1 - 0.01 14.3 0.1 0.012 14.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Laminin_II PF06009.7 CCC71037.1 - 0.025 14.3 0.3 0.057 13.1 0.1 1.7 1 1 1 2 2 2 0 Laminin Domain II SH PF01445.12 CCC71037.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Viral small hydrophobic protein DUF1690 PF07956.6 CCC71037.1 - 0.15 12.0 0.6 0.31 11.0 0.3 1.6 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) Neugrin PF06413.6 CCC71038.1 - 5.5e-10 39.4 0.9 1.2e-09 38.3 0.6 1.5 1 1 0 1 1 1 1 Neugrin Sigma70_r4 PF04545.11 CCC71038.1 - 9.4e-05 21.6 1.5 0.00028 20.1 0.1 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_11 PF08279.7 CCC71038.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.6 1 0 0 1 1 1 1 HTH domain MarR_2 PF12802.2 CCC71038.1 - 0.0039 16.8 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 MarR family HTH_7 PF02796.10 CCC71038.1 - 0.034 13.9 0.6 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_32 PF13565.1 CCC71038.1 - 0.038 14.7 0.7 0.16 12.7 0.1 2.4 2 1 1 3 3 3 0 Homeodomain-like domain HTH_24 PF13412.1 CCC71038.1 - 0.048 13.0 0.0 0.1 12.0 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF3355 PF11835.3 CCC71038.1 - 0.051 13.3 0.4 0.083 12.6 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3355) HTH_23 PF13384.1 CCC71038.1 - 0.054 13.1 0.2 1 9.1 0.0 2.7 2 1 0 2 2 2 0 Homeodomain-like domain MarR PF01047.17 CCC71038.1 - 0.076 12.7 0.0 0.23 11.1 0.0 1.9 1 0 0 1 1 1 0 MarR family VID27 PF08553.5 CCC71039.1 - 6.7e-285 947.3 15.6 8.1e-285 947.0 10.8 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein DUF2697 PF10906.3 CCC71040.1 - 1.3e-26 92.3 0.9 1.5e-26 92.1 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2697) Ost4 PF10215.4 CCC71041.1 - 1.8e-12 46.4 1.5 1.9e-12 46.4 1.1 1.0 1 0 0 1 1 1 1 Oligosaccaryltransferase KH_1 PF00013.24 CCC71042.1 - 2.1e-05 24.0 0.0 4.6e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 CCC71042.1 - 0.014 14.9 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 KH domain Rhabdo_NV PF02484.10 CCC71042.1 - 0.084 12.7 0.1 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Rhabdovirus Non-virion protein HSP70 PF00012.15 CCC71043.1 - 1.6e-236 786.0 8.4 1.7e-236 785.8 5.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCC71043.1 - 3.3e-17 62.1 0.7 1e-15 57.1 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 CCC71043.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.6 CCC71043.1 - 0.032 13.1 0.0 0.21 10.5 0.0 2.2 2 0 0 2 2 2 0 StbA protein DUF2603 PF10788.4 CCC71043.1 - 0.063 13.0 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2603) FtsA PF14450.1 CCC71043.1 - 0.19 11.5 8.1 5.1 6.9 0.2 4.4 2 1 0 3 3 3 0 Cell division protein FtsA Rick_17kDa_Anti PF05433.10 CCC71044.1 - 1.8e-07 30.6 2.8 1.8e-07 30.6 1.9 1.9 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 CCC71044.1 - 0.0021 17.7 9.1 0.0021 17.7 6.3 1.8 2 1 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_Omp PF13488.1 CCC71044.1 - 0.017 14.7 5.9 0.033 13.8 0.4 2.6 1 1 0 2 2 2 0 Glycine zipper RIO1 PF01163.17 CCC71045.1 - 8.1e-43 145.9 0.4 1.3e-42 145.3 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 CCC71045.1 - 5.4e-31 106.5 0.1 1.1e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 CCC71045.1 - 5.1e-06 26.3 0.1 0.13 12.0 0.1 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CCC71045.1 - 0.0036 16.4 0.1 0.24 10.4 0.0 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CCC71045.1 - 0.067 12.3 0.1 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Daxx PF03344.10 CCC71045.1 - 1.6 7.0 16.1 2.2 6.6 11.2 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 CCC71045.1 - 1.8 6.4 13.9 2.7 5.9 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 CCC71045.1 - 2.3 6.0 17.8 3 5.6 12.4 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 CCC71045.1 - 3.6 7.2 14.3 5.6 6.5 9.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pox_Ag35 PF03286.9 CCC71045.1 - 5.7 6.4 8.9 10 5.5 6.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein NOA36 PF06524.7 CCC71045.1 - 7.7 5.6 11.3 12 4.9 7.8 1.3 1 0 0 1 1 1 0 NOA36 protein Rtt106 PF08512.7 CCC71046.1 - 1.2e-26 92.4 0.9 2.5e-26 91.4 0.6 1.6 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DUF4647 PF15504.1 CCC71046.1 - 0.041 12.7 6.5 0.066 12.0 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Daxx PF03344.10 CCC71046.1 - 1.7 7.0 35.1 2.9 6.2 24.3 1.3 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 CCC71046.1 - 7.4 4.3 35.7 11 3.7 24.8 1.1 1 0 0 1 1 1 0 Nop14-like family adh_short_C2 PF13561.1 CCC71047.1 - 1.5e-26 93.6 0.0 1.8e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 CCC71047.1 - 5.9e-17 62.0 0.0 9e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCC71047.1 - 0.00011 21.9 0.0 0.00019 21.1 0.0 1.3 1 0 0 1 1 1 1 KR domain SMK-1 PF04802.10 CCC71048.1 - 4.8e-63 212.1 10.7 4.8e-63 212.1 7.4 2.7 3 0 0 3 3 3 1 Component of IIS longevity pathway SMK-1 YjeF_N PF03853.10 CCC71050.1 - 1.5e-36 125.5 0.0 1.8e-36 125.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus Endotoxin_C PF03944.9 CCC71050.1 - 0.067 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 delta endotoxin NYD-SP28 PF14772.1 CCC71051.1 - 0.054 13.6 7.2 0.81 9.8 0.7 2.5 2 0 0 2 2 2 0 Sperm tail ADH_zinc_N PF00107.21 CCC71052.1 - 5e-15 55.1 0.0 8.1e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCC71052.1 - 6.1e-06 25.9 0.1 8.7e-05 22.2 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 CCC71052.1 - 0.054 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Pro-MCH PF05824.7 CCC71052.1 - 0.1 12.1 0.0 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Pro-melanin-concentrating hormone (Pro-MCH) RRM_1 PF00076.17 CCC71053.1 - 1.8e-14 53.1 0.0 3.8e-06 26.4 0.0 3.7 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC71053.1 - 0.002 18.0 0.0 0.028 14.3 0.0 2.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3213 PF11491.3 CCC71055.1 - 0.0042 16.9 0.1 0.0087 15.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3213) SUR7 PF06687.7 CCC71056.1 - 9.2e-27 93.9 18.4 1.1e-26 93.7 12.8 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 CCC71056.1 - 0.0022 17.7 10.3 0.0022 17.7 7.1 1.8 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF1218 PF06749.7 CCC71056.1 - 0.055 13.9 1.0 0.055 13.9 0.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1218) Chitin_synth_1 PF01644.12 CCC71059.1 - 1e-73 246.5 0.9 1.6e-73 245.8 0.6 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 CCC71059.1 - 9e-25 86.1 0.2 2e-24 85.0 0.1 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 CCC71059.1 - 4.9e-19 68.1 4.2 4e-14 51.9 0.4 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 CCC71059.1 - 4.8e-13 49.2 0.3 4.8e-13 49.2 0.2 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 CCC71059.1 - 1.7e-10 41.1 0.0 6.5e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 GATase_4 PF13230.1 CCC71060.1 - 5e-19 68.0 0.0 1.7e-18 66.3 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 CCC71060.1 - 2.1e-11 43.8 0.0 5e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_2 PF00310.16 CCC71060.1 - 1.1e-09 37.4 0.0 4.2e-08 32.3 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 CCC71060.1 - 0.0038 16.9 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF1651 PF07864.6 CCC71062.1 - 0.26 11.4 5.7 5.3 7.2 0.3 3.1 1 1 4 5 5 5 0 Protein of unknown function (DUF1651) Chordopox_A13L PF05961.6 CCC71062.1 - 0.42 10.5 9.4 8.7 6.3 0.2 3.6 1 1 4 5 5 5 0 Chordopoxvirus A13L protein Innate_immun PF12782.2 CCC71062.1 - 1.1 8.4 18.8 1.6 7.8 13.0 1.3 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Arm PF00514.18 CCC71063.1 - 2.4e-82 268.2 18.5 1.9e-13 49.6 0.0 9.0 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat IBB PF01749.15 CCC71063.1 - 1e-25 89.7 7.4 1.9e-25 88.8 5.1 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.1 CCC71063.1 - 9.8e-20 70.6 0.6 6.4e-06 26.3 0.0 5.1 1 1 3 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 CCC71063.1 - 1.4e-18 66.8 2.6 2e-05 24.9 0.1 6.3 5 2 2 7 7 7 4 HEAT-like repeat HEAT PF02985.17 CCC71063.1 - 1.4e-10 40.3 0.0 3.4 8.0 0.0 7.4 7 0 0 7 7 7 2 HEAT repeat Arm_2 PF04826.8 CCC71063.1 - 3.5e-05 23.0 0.0 1.2 8.1 0.0 3.8 3 2 0 3 3 3 2 Armadillo-like Proteasom_PSMB PF10508.4 CCC71063.1 - 5.9e-05 21.5 0.6 0.083 11.1 0.0 2.9 2 1 1 3 3 3 2 Proteasome non-ATPase 26S subunit V-ATPase_H_C PF11698.3 CCC71063.1 - 0.0016 18.3 0.8 2.7 7.9 0.0 4.3 3 1 3 6 6 6 2 V-ATPase subunit H HEAT_PBS PF03130.11 CCC71063.1 - 0.0025 18.1 3.1 8.8 7.1 0.0 4.8 5 0 0 5 5 4 1 PBS lyase HEAT-like repeat DUF3552 PF12072.3 CCC71063.1 - 0.15 11.2 7.6 0.27 10.4 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) SAPS PF04499.10 CCC71063.1 - 0.35 9.4 5.9 0.091 11.3 1.0 2.3 3 1 0 3 3 3 0 SIT4 phosphatase-associated protein Tim17 PF02466.14 CCC71065.1 - 3.5e-45 153.1 6.3 5.6e-45 152.5 4.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DLH PF01738.13 CCC71065.1 - 0.22 10.7 0.0 0.22 10.7 0.0 2.5 2 1 1 3 3 3 0 Dienelactone hydrolase family KH_3 PF13014.1 CCC71066.1 - 0.016 14.8 0.0 0.068 12.8 0.0 2.0 2 0 0 2 2 2 0 KH domain UCH PF00443.24 CCC71067.1 - 1.3e-55 188.3 3.3 1.3e-55 188.3 2.3 2.6 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC71067.1 - 1.2e-20 74.1 0.5 1.2e-20 74.1 0.3 3.4 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Prenyltrans PF00432.16 CCC71067.1 - 0.18 11.3 0.0 0.47 10.0 0.0 1.6 1 0 0 1 1 1 0 Prenyltransferase and squalene oxidase repeat Ribosomal_L11 PF00298.14 CCC71068.1 - 8.8e-27 93.0 0.3 1.4e-26 92.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L11_N PF03946.9 CCC71068.1 - 1.4e-24 85.2 0.4 2.3e-24 84.6 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Pkinase PF00069.20 CCC71069.1 - 2.1e-62 210.6 0.0 3.2e-62 210.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71069.1 - 6.3e-22 77.8 0.0 1.1e-21 77.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC71069.1 - 0.048 12.6 0.0 0.077 11.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.27 CCC71070.1 - 1.3e-10 40.7 0.6 0.00096 18.9 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat HPS3_N PF14761.1 CCC71070.1 - 0.048 13.0 0.2 2.6 7.3 0.0 2.7 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 DASH_Dam1 PF08653.5 CCC71070.1 - 0.05 13.3 0.3 0.14 11.9 0.2 1.7 1 0 0 1 1 1 0 DASH complex subunit Dam1 GAT PF03127.9 CCC71071.1 - 0.054 13.4 0.5 0.16 11.9 0.3 1.8 1 1 0 1 1 1 0 GAT domain DUF4114 PF13448.1 CCC71071.1 - 0.72 10.7 6.1 0.44 11.4 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4114) RuBisCO_small PF00101.15 CCC71075.1 - 0.14 12.0 0.5 15 5.5 0.2 2.4 2 0 0 2 2 2 0 Ribulose bisphosphate carboxylase, small chain FA_desaturase PF00487.19 CCC71076.1 - 0.068 12.5 0.1 0.088 12.2 0.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase adh_short PF00106.20 CCC71077.1 - 6e-07 29.5 0.0 1.1e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 CCC71077.1 - 6.5e-06 25.9 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Exo_endo_phos_2 PF14529.1 CCC71077.1 - 3.4e-05 23.4 0.0 0.13 11.8 0.0 2.3 2 0 0 2 2 2 2 Endonuclease-reverse transcriptase adh_short_C2 PF13561.1 CCC71077.1 - 0.04 13.6 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Bac_rhodopsin PF01036.13 CCC71077.1 - 0.057 12.7 0.2 0.057 12.7 0.1 1.5 2 0 0 2 2 2 0 Bacteriorhodopsin-like protein Ras PF00071.17 CCC71078.1 - 4e-45 153.1 0.0 7.6e-45 152.2 0.0 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 CCC71078.1 - 2.4e-15 57.0 0.4 2.5e-14 53.8 0.0 2.6 2 2 0 2 2 2 1 Miro-like protein Arf PF00025.16 CCC71078.1 - 4.8e-05 22.6 0.1 0.00042 19.6 0.1 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCC71078.1 - 0.0013 18.2 1.5 0.0023 17.3 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain LAM_C PF12544.3 CCC71078.1 - 0.032 14.2 1.3 0.032 14.2 0.9 2.0 2 0 0 2 2 2 0 Lysine-2,3-aminomutase Gtr1_RagA PF04670.7 CCC71078.1 - 0.042 12.9 1.2 0.24 10.4 0.0 2.6 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region Suf PF05843.9 CCC71078.1 - 0.048 13.3 8.4 0.065 12.9 5.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Zip PF02535.17 CCC71078.1 - 0.18 10.7 0.5 0.19 10.6 0.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Herpes_DNAp_acc PF04929.7 CCC71078.1 - 9 5.1 13.6 14 4.5 9.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Ribosomal_S3_C PF00189.15 CCC71079.1 - 1e-15 57.6 0.1 1.9e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 CCC71079.1 - 6.8e-12 44.7 0.1 2.4e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 KH domain Ribosomal_L22 PF00237.14 CCC71080.1 - 1.6e-20 72.9 0.0 3e-20 72.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Beta-APP PF03494.8 CCC71081.1 - 0.58 9.6 4.8 1.3 8.5 3.3 1.5 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) RRM_1 PF00076.17 CCC71082.1 - 1.4e-28 98.3 2.9 1.8e-17 62.6 0.0 3.4 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC71082.1 - 5.4e-22 77.5 0.3 2.9e-13 49.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC71082.1 - 4.3e-10 39.2 0.4 2.6e-05 23.9 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCC71082.1 - 0.0013 18.4 0.0 0.0035 17.0 0.0 1.7 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif C-term_anchor PF13461.1 CCC71082.1 - 3.7 8.0 5.7 19 5.8 0.5 2.8 1 1 1 2 2 2 0 Cell-wall surface anchor repeat Apc1 PF12859.2 CCC71084.1 - 2.1e-14 53.5 4.4 9.2e-14 51.5 1.0 3.6 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 CCC71084.1 - 0.91 9.8 7.9 12 6.3 0.3 4.3 3 0 0 3 3 3 0 Proteasome/cyclosome repeat PS_Dcarbxylase PF02666.10 CCC71085.1 - 2.6e-76 255.4 0.0 3.7e-76 254.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase FAA_hydrolase PF01557.13 CCC71086.1 - 2.8e-43 147.8 0.0 3.5e-43 147.5 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family bZIP_1 PF00170.16 CCC71087.1 - 1.6e-06 27.9 3.6 4.4e-06 26.5 2.5 1.7 1 0 0 1 1 1 1 bZIP transcription factor Aft1_OSA PF11785.3 CCC71087.1 - 1.8e-06 28.4 0.4 1.8e-06 28.4 0.3 4.3 6 0 0 6 6 6 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 CCC71087.1 - 0.0014 18.3 6.3 0.0031 17.2 4.4 1.5 1 0 0 1 1 1 1 Basic region leucine zipper PRTP PF01366.13 CCC71087.1 - 0.06 11.3 3.7 0.11 10.5 2.6 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein ABC_tran_2 PF12848.2 CCC71087.1 - 0.94 9.3 9.4 0.32 10.8 3.9 2.1 1 1 1 2 2 2 0 ABC transporter GTP_EFTU PF00009.22 CCC71091.1 - 4.5e-53 179.4 0.0 8.4e-53 178.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 CCC71091.1 - 2.5e-13 49.6 0.0 8.4e-13 48.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CCC71091.1 - 2.1e-08 33.8 0.0 5.2e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CCC71091.1 - 6.2e-08 32.6 0.0 1.7e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 CCC71091.1 - 0.0006 19.3 0.0 0.0023 17.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 CCC71091.1 - 0.0026 17.6 0.0 0.0069 16.3 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase OrfB_Zn_ribbon PF07282.6 CCC71092.1 - 0.041 13.5 0.8 0.056 13.1 0.6 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain UPF0547 PF10571.4 CCC71092.1 - 0.062 13.0 1.6 0.062 13.0 1.1 2.1 2 1 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.5 CCC71092.1 - 0.14 12.1 3.3 0.69 9.9 0.4 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DZR PF12773.2 CCC71092.1 - 0.21 11.4 1.9 0.34 10.7 1.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.16 CCC71092.1 - 0.35 10.7 3.4 2.6 7.9 2.3 2.0 1 1 0 1 1 1 0 IBR domain TF_Zn_Ribbon PF08271.7 CCC71092.1 - 0.85 8.9 3.2 0.52 9.6 0.3 2.0 1 1 0 1 1 1 0 TFIIB zinc-binding zf-C2H2 PF00096.21 CCC71092.1 - 1.1 9.7 3.6 8.1 7.0 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type Ribosomal_L44 PF00935.14 CCC71093.1 - 4.2e-34 116.3 10.7 6.1e-34 115.8 7.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 Pkinase PF00069.20 CCC71094.1 - 5.8e-59 199.3 0.3 2.7e-39 134.8 0.1 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71094.1 - 2.5e-26 92.3 0.3 8.9e-20 70.8 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 CCC71094.1 - 0.0012 17.9 0.2 0.017 14.2 0.0 2.4 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCC71094.1 - 0.0015 17.6 0.1 0.0064 15.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.19 CCC71094.1 - 0.0085 16.5 2.4 0.012 16.1 0.2 2.5 2 0 0 2 2 2 1 Protein kinase C terminal domain Seadorna_VP7 PF07387.6 CCC71094.1 - 0.021 13.6 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 CCC71094.1 - 0.04 13.6 0.1 0.75 9.4 0.1 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family Asparaginase PF00710.15 CCC71095.1 - 9.3e-15 54.2 6.7 3e-14 52.6 4.7 1.9 1 1 0 1 1 1 1 Asparaginase Ammonium_transp PF00909.16 CCC71096.1 - 2e-122 408.5 27.2 2.2e-122 408.3 18.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2207 PF09972.4 CCC71096.1 - 4.7 5.6 10.7 0.83 8.1 1.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Prefoldin_2 PF01920.15 CCC71097.1 - 3.6e-21 74.9 14.3 4.3e-21 74.6 9.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Nup54 PF13874.1 CCC71097.1 - 0.024 14.2 0.6 0.024 14.2 0.4 2.0 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF4164 PF13747.1 CCC71097.1 - 0.11 12.6 4.5 0.35 11.0 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) ATG16 PF08614.6 CCC71097.1 - 0.13 12.1 8.8 0.5 10.1 1.3 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Spc7 PF08317.6 CCC71097.1 - 0.17 10.4 12.0 0.22 10.1 8.3 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.10 CCC71097.1 - 0.39 10.2 14.0 0.19 11.1 1.3 2.2 1 1 1 2 2 2 0 Septum formation initiator Laminin_II PF06009.7 CCC71097.1 - 0.4 10.4 5.0 0.53 10.0 3.0 1.6 1 1 0 1 1 1 0 Laminin Domain II Enkurin PF13864.1 CCC71097.1 - 0.42 10.8 8.5 0.67 10.2 1.1 2.2 2 0 0 2 2 2 0 Calmodulin-binding CENP-F_leu_zip PF10473.4 CCC71097.1 - 2.3 8.0 14.8 1.8 8.4 1.4 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 CCC71097.1 - 4.4 7.3 10.8 2.3 8.2 1.3 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SlyX PF04102.7 CCC71097.1 - 4.7 7.6 9.7 0.63 10.4 0.3 2.7 2 1 1 3 3 3 0 SlyX DUF4140 PF13600.1 CCC71097.1 - 5.8 7.4 7.3 2.2 8.7 0.8 2.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) A_deaminase PF00962.17 CCC71098.1 - 1.6e-89 300.0 0.0 1.8e-89 299.9 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase Pkinase PF00069.20 CCC71099.1 - 3.9e-32 111.4 0.3 7.3e-32 110.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71099.1 - 1.3e-12 47.3 0.0 3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase YrbL-PhoP_reg PF10707.4 CCC71099.1 - 0.13 11.5 0.0 0.13 11.5 0.0 1.9 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL zf-AN1 PF01428.11 CCC71100.1 - 8e-12 44.8 10.9 8e-12 44.8 7.6 2.1 2 0 0 2 2 2 1 AN1-like Zinc finger INSIG PF07281.7 CCC71101.1 - 3.1e-09 36.4 7.1 1e-08 34.7 4.9 1.8 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) T_cell_tran_alt PF15128.1 CCC71101.1 - 2.4 7.6 4.6 10 5.6 0.3 2.7 2 1 1 3 3 3 0 T-cell leukemia translocation-altered Pga1 PF10333.4 CCC71102.1 - 5.9e-21 74.9 4.8 1.9e-20 73.2 3.4 1.7 1 1 0 1 1 1 1 GPI-Mannosyltransferase II co-activator CryBP1 PF07029.6 CCC71102.1 - 0.11 12.1 0.1 0.17 11.6 0.1 1.2 1 0 0 1 1 1 0 CryBP1 protein ERM PF00769.14 CCC71103.1 - 0.1 12.1 2.7 0.12 11.8 1.9 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family YGGT PF02325.12 CCC71103.1 - 9.2 6.2 8.7 9.1 6.3 1.0 3.3 3 0 0 3 3 3 0 YGGT family Tub_2 PF04525.7 CCC71105.1 - 0.098 12.0 0.0 0.098 12.0 0.0 1.0 1 0 0 1 1 1 0 Tubby C 2 DUF782 PF05614.6 CCC71106.1 - 0.02 15.0 0.0 0.025 14.7 0.0 1.2 1 0 0 1 1 1 0 Circovirus protein of unknown function (DUF782) DUF2009 PF09418.5 CCC71107.1 - 5.5e-224 744.0 3.8 5.5e-224 744.0 2.7 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 CCC71107.1 - 4.8e-07 29.5 4.6 8.3e-07 28.7 3.2 1.4 1 0 0 1 1 1 1 B-box zinc finger IBR PF01485.16 CCC71107.1 - 0.016 15.0 3.0 0.039 13.8 2.1 1.6 1 0 0 1 1 1 0 IBR domain eIF-4B PF06273.6 CCC71107.1 - 0.96 8.1 4.7 1.8 7.2 3.3 1.3 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B RPN7 PF10602.4 CCC71107.1 - 9.6 5.5 12.0 2.1 7.6 0.2 3.2 3 0 0 3 3 3 0 26S proteasome subunit RPN7 PGA2 PF07543.7 CCC71109.1 - 6.6e-16 58.3 10.6 1e-13 51.2 7.3 2.0 1 1 0 1 1 1 1 Protein trafficking PGA2 Ferritin PF00210.19 CCC71109.1 - 0.0088 15.8 2.4 0.011 15.4 1.6 1.1 1 0 0 1 1 1 1 Ferritin-like domain DUF3323 PF11796.3 CCC71109.1 - 0.086 12.1 0.2 0.088 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) DUF1378 PF07125.6 CCC71109.1 - 0.17 11.8 1.5 0.72 9.8 0.1 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1378) DivIC PF04977.10 CCC71109.1 - 0.58 9.6 8.2 6.2 6.3 0.1 2.3 1 1 1 2 2 2 0 Septum formation initiator COX16 PF14138.1 CCC71109.1 - 0.77 9.9 6.4 0.35 11.0 2.0 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein COX16 YqzH PF14164.1 CCC71109.1 - 1.1 9.2 6.5 1.6 8.7 1.3 2.7 2 1 1 3 3 3 0 YqzH-like protein CaMBD PF02888.11 CCC71109.1 - 1.6 8.6 7.4 2.1 8.2 1.3 2.3 1 1 1 2 2 2 0 Calmodulin binding domain DUF1049 PF06305.6 CCC71109.1 - 1.9 8.0 3.7 14 5.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF496 PF04363.7 CCC71109.1 - 3.4 7.5 8.9 0.41 10.4 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF496) RNA_pol_3_Rpc31 PF11705.3 CCC71110.1 - 7.3e-66 222.4 17.6 9.6e-66 222.0 12.2 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Cytomega_UL84 PF06284.6 CCC71110.1 - 0.47 8.7 2.0 0.6 8.4 1.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein C2 PF00168.25 CCC71111.1 - 0.00073 19.3 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 C2 domain DDA1 PF10172.4 CCC71111.1 - 0.022 14.5 0.7 0.091 12.5 0.0 2.4 3 0 0 3 3 3 0 Det1 complexing ubiquitin ligase Phage_F PF02305.12 CCC71111.1 - 0.031 12.8 0.4 0.044 12.3 0.3 1.2 1 0 0 1 1 1 0 Capsid protein (F protein) Tho2 PF11262.3 CCC71112.1 - 1.1e-55 188.8 8.2 1.1e-55 188.8 5.7 3.7 3 1 0 3 3 3 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 CCC71112.1 - 1.7e-27 94.9 0.4 5.5e-27 93.3 0.3 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit SF3b10 PF07189.6 CCC71113.1 - 4.6e-22 77.6 1.7 5.5e-22 77.3 1.2 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) DeoRC PF00455.17 CCC71113.1 - 0.045 13.3 0.1 0.052 13.1 0.1 1.1 1 0 0 1 1 1 0 DeoR C terminal sensor domain SYCE1 PF15233.1 CCC71113.1 - 0.17 11.8 3.8 0.21 11.4 2.6 1.0 1 0 0 1 1 1 0 Synaptonemal complex central element protein 1 CAP_N PF01213.14 CCC71115.1 - 3.3e-102 341.9 8.1 4.9e-102 341.4 5.6 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 CCC71115.1 - 1e-63 213.4 1.4 1.7e-63 212.7 0.7 1.6 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal Mito_fiss_reg PF05308.6 CCC71115.1 - 0.039 13.3 14.4 0.11 11.8 2.1 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator TBCC PF07986.7 CCC71115.1 - 0.042 13.2 2.2 1 8.8 0.6 2.5 2 0 0 2 2 2 0 Tubulin binding cofactor C S4 PF01479.20 CCC71116.1 - 3.2e-16 58.5 0.0 6.3e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 CCC71116.1 - 0.00075 19.0 0.0 0.0021 17.6 0.0 1.7 1 0 0 1 1 1 1 S4 domain KapB PF08810.5 CCC71116.1 - 0.031 14.3 5.6 0.066 13.2 0.1 2.8 2 0 0 2 2 2 0 Kinase associated protein B Eaf7 PF07904.8 CCC71117.1 - 1.2e-30 105.3 0.5 1.2e-30 105.3 0.3 3.2 2 2 0 2 2 2 1 Chromatin modification-related protein EAF7 FKBP_C PF00254.23 CCC71118.1 - 2.6e-32 110.7 0.0 3.1e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ADH_zinc_N PF00107.21 CCC71119.1 - 3.6e-14 52.4 0.0 5.9e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCC71119.1 - 2.2e-05 24.1 0.3 0.00041 20.0 0.1 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Semialdhyde_dh PF01118.19 CCC71119.1 - 0.053 13.8 0.0 0.093 13.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain rve PF00665.21 CCC71120.1 - 1.9e-18 66.6 0.1 1.1e-17 64.2 0.0 2.3 2 0 0 2 2 2 1 Integrase core domain Mucin PF01456.12 CCC71120.1 - 7.3 6.3 23.6 12 5.6 16.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RVT_1 PF00078.22 CCC71121.1 - 8.1e-16 58.0 0.1 8.2e-14 51.4 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_2 PF07727.9 CCC71121.1 - 0.078 11.9 0.4 0.28 10.1 0.3 1.8 1 1 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) GNAT_acetyltr_2 PF13718.1 CCC71122.1 - 1.4e-80 269.2 0.0 3.5e-80 267.9 0.0 1.7 2 0 0 2 2 2 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 CCC71122.1 - 4.8e-66 221.7 0.0 2e-65 219.7 0.0 2.0 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 CCC71122.1 - 1.3e-39 133.7 0.1 5.7e-39 131.7 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 CCC71122.1 - 8.2e-38 128.5 1.2 2.6e-37 126.9 0.9 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain Sigma70_r4_2 PF08281.7 CCC71122.1 - 0.0067 15.8 1.3 0.3 10.5 0.0 3.2 3 0 0 3 3 3 1 Sigma-70, region 4 Acetyltransf_7 PF13508.1 CCC71122.1 - 0.065 13.4 0.0 0.21 11.7 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tom22 PF04281.8 CCC71123.1 - 3.5e-49 165.8 0.9 4e-49 165.6 0.6 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 DUF349 PF03993.7 CCC71123.1 - 0.052 13.7 0.2 0.1 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF349) Adeno_terminal PF02459.10 CCC71123.1 - 0.074 11.2 0.1 0.091 10.9 0.1 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein CDP-OH_P_transf PF01066.16 CCC71124.1 - 4.4e-15 55.8 15.1 5.4e-14 52.3 10.5 2.9 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase VIT1 PF01988.14 CCC71124.1 - 3 7.2 5.3 0.6 9.5 1.0 1.8 2 0 0 2 2 2 0 VIT family AAA_18 PF13238.1 CCC71125.1 - 6.6e-07 29.6 0.0 6.1e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCC71125.1 - 4.1e-06 27.6 0.1 1.1e-05 26.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain tRNA_lig_kinase PF08303.6 CCC71125.1 - 0.032 14.1 0.3 0.38 10.6 0.2 2.1 1 1 0 1 1 1 0 tRNA ligase kinase domain AAA_33 PF13671.1 CCC71125.1 - 0.058 13.2 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 CCC71125.1 - 0.088 12.4 0.0 0.3 10.6 0.0 1.8 2 1 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.22 CCC71125.1 - 0.089 13.0 0.2 0.15 12.3 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 CCC71125.1 - 0.099 12.6 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF927 PF06048.6 CCC71125.1 - 0.11 11.7 0.0 0.43 9.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF927) DSPc PF00782.15 CCC71126.1 - 1.5e-09 37.5 0.0 3.6e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCC71126.1 - 0.002 17.4 0.0 0.0039 16.5 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCC71126.1 - 0.0033 17.4 0.1 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 CCC71126.1 - 0.058 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family AD PF09793.4 CCC71127.1 - 3.9e-23 81.0 0.1 6e-23 80.5 0.1 1.3 1 0 0 1 1 1 1 Anticodon-binding domain IL15 PF02372.10 CCC71127.1 - 0.019 14.7 0.2 0.025 14.3 0.2 1.3 1 0 0 1 1 1 0 Interleukin 15 DUF1967 PF09269.6 CCC71127.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) LSM14 PF12701.2 CCC71127.1 - 0.027 14.2 2.0 0.28 11.0 0.9 2.6 2 1 0 2 2 2 0 Scd6-like Sm domain DUF3402 PF11882.3 CCC71128.1 - 4.8e-85 286.0 12.3 1e-83 281.7 8.6 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 CCC71128.1 - 5.4e-58 196.1 2.5 5.4e-58 196.1 1.8 1.7 2 0 0 2 2 2 1 N1221-like protein MFS_1 PF07690.11 CCC71129.1 - 5.5e-21 74.6 43.5 1e-20 73.7 30.2 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Spc97_Spc98 PF04130.8 CCC71130.1 - 1.1e-64 218.7 25.4 1.7e-64 218.0 17.6 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family Gar1 PF04410.9 CCC71131.1 - 7.7e-48 161.8 0.3 7.7e-48 161.8 0.2 2.3 3 1 1 4 4 4 1 Gar1/Naf1 RNA binding region PIGA PF08288.7 CCC71131.1 - 0.043 14.1 0.0 0.068 13.5 0.0 1.3 1 0 0 1 1 1 0 PIGA (GPI anchor biosynthesis) Cyclin_N PF00134.18 CCC71132.1 - 7.8e-16 57.7 0.6 2.3e-15 56.2 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain PDZ_1 PF12812.2 CCC71133.1 - 5.6e-50 167.1 0.0 1.1e-35 121.3 0.0 3.1 3 0 0 3 3 3 2 PDZ-like domain PDZ_2 PF13180.1 CCC71133.1 - 1.2e-12 47.4 1.4 0.00076 19.3 0.3 4.6 4 0 0 4 4 4 2 PDZ domain Trypsin_2 PF13365.1 CCC71133.1 - 4.3e-12 46.0 0.1 1e-10 41.6 0.0 2.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 CCC71133.1 - 1.9e-08 34.3 0.0 0.00023 21.2 0.0 3.1 3 0 0 3 3 3 2 PDZ domain (Also known as DHR or GLGF) Trypsin PF00089.21 CCC71133.1 - 0.00013 21.6 0.0 0.00033 20.2 0.0 1.7 1 0 0 1 1 1 1 Trypsin Tricorn_PDZ PF14685.1 CCC71133.1 - 0.0016 18.2 0.1 0.95 9.2 0.0 3.2 3 0 0 3 3 3 1 Tricorn protease PDZ domain DUF31 PF01732.11 CCC71133.1 - 0.013 14.8 0.1 0.025 13.9 0.1 1.4 1 0 0 1 1 1 0 Putative peptidase (DUF31) Peptidase_S7 PF00949.16 CCC71133.1 - 0.037 13.4 0.1 0.1 12.0 0.1 1.7 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease ThiS PF02597.15 CCC71133.1 - 0.13 12.7 0.7 51 4.3 0.0 3.5 2 1 1 3 3 3 0 ThiS family Ribosomal_L35p PF01632.14 CCC71134.1 - 7.6e-06 25.7 3.0 9.6e-06 25.4 2.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 TPR_11 PF13414.1 CCC71135.1 - 1.6e-44 149.4 43.3 1.6e-16 59.6 0.8 6.5 3 2 6 9 9 9 9 TPR repeat TPR_1 PF00515.23 CCC71135.1 - 1e-31 107.2 33.5 3.1e-07 29.7 0.4 10.1 9 2 1 10 10 10 7 Tetratricopeptide repeat TPR_2 PF07719.12 CCC71135.1 - 3.8e-31 104.4 31.2 3.7e-06 26.4 0.4 10.8 11 1 0 11 11 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 CCC71135.1 - 1.8e-23 82.6 11.2 4.2e-07 30.4 0.0 6.7 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCC71135.1 - 1.9e-19 69.3 24.7 0.0002 21.2 0.3 7.5 2 2 7 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.1 CCC71135.1 - 2.6e-19 67.4 34.4 0.0015 18.1 0.2 9.6 8 2 2 10 10 10 5 Tetratricopeptide repeat TPR_17 PF13431.1 CCC71135.1 - 4e-19 67.1 15.0 0.012 15.7 0.0 8.9 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_19 PF14559.1 CCC71135.1 - 7.9e-17 61.3 15.8 6.8e-05 23.1 0.4 7.1 5 2 3 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 CCC71135.1 - 1.8e-16 59.1 10.4 0.029 14.9 0.2 10.2 4 3 6 10 10 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCC71135.1 - 2.4e-11 42.5 18.4 0.098 12.5 0.2 8.9 8 1 1 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 CCC71135.1 - 1.5e-09 37.8 17.2 0.0047 17.0 1.4 5.3 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 CCC71135.1 - 3.9e-07 29.8 2.4 2.6 7.9 0.0 5.9 6 0 0 6 6 5 2 Tetratricopeptide repeat DUF3808 PF10300.4 CCC71135.1 - 8.3e-05 21.3 12.3 0.00063 18.4 0.1 4.1 3 1 2 5 5 5 2 Protein of unknown function (DUF3808) DUF4230 PF14014.1 CCC71135.1 - 0.0018 18.1 1.7 0.0043 16.9 1.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4230) Exonuc_VII_S PF02609.11 CCC71135.1 - 0.0023 17.6 4.0 0.19 11.5 0.3 3.7 3 0 0 3 3 3 1 Exonuclease VII small subunit TPR_6 PF13174.1 CCC71135.1 - 0.0043 17.4 26.5 4 8.0 0.0 9.0 10 1 0 10 10 9 1 Tetratricopeptide repeat RPN7 PF10602.4 CCC71135.1 - 0.013 14.9 4.0 2.6 7.3 0.0 4.0 4 1 0 4 4 4 0 26S proteasome subunit RPN7 SHNi-TPR PF10516.4 CCC71135.1 - 0.097 11.9 5.1 1.3 8.3 0.1 4.8 5 0 0 5 5 4 0 SHNi-TPR TPR_20 PF14561.1 CCC71135.1 - 0.23 11.6 10.1 0.15 12.2 0.5 4.5 5 1 1 6 6 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 CCC71135.1 - 0.92 9.3 16.8 2.6 7.9 0.3 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2392 PF10288.4 CCC71136.1 - 1.3e-30 105.8 0.2 6.8e-30 103.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) Zn_Tnp_IS91 PF14319.1 CCC71136.1 - 0.0078 15.7 1.4 0.018 14.5 1.0 1.6 1 0 0 1 1 1 1 Transposase zinc-binding domain GLF PF03275.8 CCC71136.1 - 0.024 14.1 0.8 1.4 8.3 0.1 2.7 2 0 0 2 2 2 0 UDP-galactopyranose mutase Ribosomal_L17 PF01196.14 CCC71136.1 - 0.063 13.8 1.2 11 6.6 0.1 2.6 2 1 0 2 2 2 0 Ribosomal protein L17 CBF PF03914.12 CCC71136.1 - 0.077 12.4 0.2 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 CBF/Mak21 family zf-A20 PF01754.11 CCC71136.1 - 0.22 11.1 3.5 0.26 10.8 0.4 2.5 2 0 0 2 2 2 0 A20-like zinc finger GCC2_GCC3 PF07699.8 CCC71136.1 - 0.57 9.8 5.2 0.43 10.1 1.2 2.3 2 0 0 2 2 2 0 GCC2 and GCC3 DZR PF12773.2 CCC71136.1 - 1.2 8.9 5.3 0.43 10.4 1.1 2.1 3 0 0 3 3 3 0 Double zinc ribbon DCP2 PF05026.8 CCC71137.1 - 9.8e-33 111.9 0.6 2.3e-32 110.7 0.5 1.7 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 CCC71137.1 - 1.1e-13 50.9 0.0 2.3e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Malate_synthase PF01274.17 CCC71138.1 - 1.2e-218 726.4 0.0 1.4e-218 726.1 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.9 CCC71138.1 - 0.031 13.1 0.0 0.053 12.4 0.0 1.3 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family GHL6 PF14871.1 CCC71138.1 - 0.08 12.9 0.1 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 FHA PF00498.21 CCC71139.1 - 8.1e-15 54.6 0.1 2.1e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 CCC71139.1 - 7.4e-06 25.6 10.5 1.2e-05 25.0 7.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 CCC71139.1 - 1.1e-05 25.4 4.5 2.1e-05 24.5 3.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 CCC71139.1 - 0.0011 18.7 3.8 0.0023 17.7 2.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 CCC71139.1 - 0.003 17.1 10.1 0.0054 16.3 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC71139.1 - 0.0033 17.1 8.1 0.0054 16.4 5.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Sec_GG PF07549.9 CCC71139.1 - 0.026 13.7 0.4 0.15 11.3 0.4 2.2 2 0 0 2 2 2 0 SecD/SecF GG Motif zf-C3HC4_2 PF13923.1 CCC71139.1 - 0.061 13.3 12.1 0.1 12.6 8.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 CCC71139.1 - 1.8 8.6 7.1 3.7 7.6 4.9 1.5 1 0 0 1 1 1 0 RING-like domain adh_short PF00106.20 CCC71140.1 - 6.8e-15 55.3 0.0 8.8e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCC71140.1 - 0.0001 22.1 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCC71140.1 - 0.0018 17.9 0.0 0.0023 17.5 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF2417 PF10329.4 CCC71141.1 - 3.2e-54 183.8 6.7 4.5e-54 183.3 4.7 1.2 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 CCC71141.1 - 9.3e-09 35.4 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC71141.1 - 0.00029 20.4 0.0 0.00056 19.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold RNA_pol_L_2 PF13656.1 CCC71142.1 - 5.8e-31 105.7 0.0 9.7e-31 105.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 CCC71142.1 - 2.9e-13 48.7 0.0 4e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain TRAP_alpha PF03896.11 CCC71142.1 - 2 7.3 6.3 2.2 7.2 4.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 CCC71142.1 - 6.4 6.3 9.3 9.1 5.8 6.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 CCC71142.1 - 7.7 4.2 7.5 8.7 4.0 5.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 CCC71142.1 - 9.9 5.6 10.8 15 5.1 7.5 1.2 1 0 0 1 1 1 0 Nucleoplasmin DEAD PF00270.24 CCC71143.1 - 2.1e-44 151.0 0.0 3.2e-43 147.1 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC71143.1 - 1.4e-29 101.7 0.1 5e-29 99.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC71143.1 - 0.00073 19.4 0.0 0.0021 17.9 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 CCC71143.1 - 0.0026 16.2 0.0 0.022 13.1 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 CCC71143.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Helicase C-terminal domain Cyt-b5 PF00173.23 CCC71144.1 - 1.4e-25 88.9 0.1 1.9e-25 88.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RRM_1 PF00076.17 CCC71145.1 - 9.2e-20 70.0 0.0 2e-19 68.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC71145.1 - 1.1e-13 50.9 0.1 2.4e-13 49.8 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC71145.1 - 1.2e-09 37.8 0.7 1.9e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 CCC71145.1 - 0.00083 19.0 0.6 0.0033 17.1 0.0 2.3 2 1 0 2 2 2 1 Limkain b1 VitD-bind_III PF09164.5 CCC71145.1 - 0.12 12.0 0.8 0.4 10.3 0.4 2.1 2 0 0 2 2 2 0 Vitamin D binding protein, domain III His_Phos_1 PF00300.17 CCC71146.1 - 2.4e-21 76.4 0.0 6.6e-21 75.0 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) Syja_N PF02383.13 CCC71147.1 - 7.4e-93 310.8 0.0 1.2e-92 310.1 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 CCC71147.1 - 4.8e-27 95.4 0.0 1.1e-26 94.2 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DNA_pol_B PF00136.16 CCC71149.1 - 8.2e-116 387.5 9.3 1.5e-115 386.6 6.5 1.5 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 CCC71149.1 - 2.3e-66 222.7 3.2 5.3e-66 221.5 2.2 1.7 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 CCC71149.1 - 4.8e-43 147.2 0.0 1.4e-42 145.7 0.0 1.8 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 CCC71149.1 - 2e-21 75.5 9.1 9.6e-21 73.3 6.3 2.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal Aa_trans PF01490.13 CCC71150.1 - 1.5e-93 313.5 32.9 1.8e-93 313.2 22.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF202 PF02656.10 CCC71150.1 - 2.5 8.3 5.8 0.49 10.6 0.1 2.9 4 1 0 4 4 4 0 Domain of unknown function (DUF202) Y_phosphatase2 PF03162.8 CCC71152.1 - 3.4e-57 192.4 0.0 4.8e-57 191.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCC71152.1 - 1e-05 25.8 0.0 8.1e-05 22.9 0.0 2.1 1 1 1 2 2 2 1 Tyrosine phosphatase family Vps39_2 PF10367.4 CCC71152.1 - 0.027 14.6 0.2 0.044 13.9 0.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DSPc PF00782.15 CCC71152.1 - 0.065 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Myc_N PF01056.13 CCC71152.1 - 0.57 9.2 3.8 0.76 8.8 2.6 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_60s PF00428.14 CCC71152.1 - 0.74 10.2 4.6 1.5 9.2 3.2 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein DAD PF02109.11 CCC71153.1 - 9.6e-40 135.1 6.3 1.3e-39 134.7 4.4 1.1 1 0 0 1 1 1 1 DAD family DUF2207 PF09972.4 CCC71153.1 - 0.077 11.5 0.4 0.087 11.3 0.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF751 PF05421.6 CCC71153.1 - 9.2 6.6 8.0 2.1 8.6 1.1 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF751) ING PF12998.2 CCC71154.1 - 7.3e-20 71.2 0.3 7.3e-20 71.2 0.2 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CCC71154.1 - 1.2e-09 37.6 8.4 2e-09 36.9 5.8 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCC71154.1 - 0.0038 16.5 2.3 0.009 15.3 1.6 1.6 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CCC71154.1 - 0.041 14.0 1.5 0.087 12.9 1.0 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain Sp100 PF03172.8 CCC71154.1 - 0.054 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Sp100 domain Muted PF14942.1 CCC71154.1 - 0.084 12.7 2.2 0.083 12.7 0.6 1.6 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein Ribosomal_S7e PF01251.13 CCC71155.1 - 4.3e-23 81.7 0.1 4.6e-23 81.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Mem_trans PF03547.13 CCC71156.1 - 3.5e-89 298.8 4.1 4.6e-89 298.4 2.8 1.2 1 0 0 1 1 1 1 Membrane transport protein Macoilin PF09726.4 CCC71156.1 - 1.8 6.7 26.7 2.4 6.3 18.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF2183 PF09949.4 CCC71157.1 - 1.3e-30 105.2 0.0 6.8e-30 102.9 0.0 2.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) Erf4 PF10256.4 CCC71157.1 - 0.043 13.6 3.6 5.2 6.9 0.0 3.7 4 0 0 4 4 4 0 Golgin subfamily A member 7/ERF4 family zf-CCCH PF00642.19 CCC71158.1 - 0.00051 19.6 0.1 0.00051 19.6 0.1 2.1 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HTH_29 PF13551.1 CCC71158.1 - 0.07 13.2 0.8 2.1 8.4 0.2 2.8 3 0 0 3 3 3 0 Winged helix-turn helix NST1 PF13945.1 CCC71159.1 - 2.9e-07 30.7 18.6 2.9e-07 30.7 12.9 6.0 4 2 1 5 5 5 1 Salt tolerance down-regulator Ras PF00071.17 CCC71160.1 - 8.3e-51 171.5 0.0 9.5e-51 171.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC71160.1 - 4.8e-15 56.0 0.0 6.6e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC71160.1 - 6.3e-10 38.5 0.0 7.7e-10 38.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 CCC71160.1 - 0.00016 21.1 0.1 0.0049 16.3 0.1 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 CCC71160.1 - 0.0033 16.8 0.0 0.036 13.4 0.0 1.9 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 CCC71160.1 - 0.049 12.8 0.0 0.068 12.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_21 PF13304.1 CCC71160.1 - 0.078 12.9 0.0 0.11 12.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 CCC71160.1 - 0.085 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DNA_topoisoIV PF00521.15 CCC71161.1 - 1.1e-123 413.3 0.0 1.1e-123 413.3 0.0 2.6 3 0 0 3 3 3 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 CCC71161.1 - 1.2e-33 115.7 5.2 3e-33 114.4 3.6 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 CCC71161.1 - 3.6e-12 46.1 0.0 1.9e-11 43.8 0.0 2.3 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 CCC71161.1 - 1.3e-10 41.0 0.0 5.3e-10 38.9 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SNN_linker PF09050.5 CCC71161.1 - 0.19 11.2 2.6 1.3 8.6 0.2 2.8 2 0 0 2 2 2 0 Stannin unstructured linker C2 PF00168.25 CCC71162.1 - 4.9e-39 132.0 9.2 1.9e-17 62.8 0.1 4.8 5 0 0 5 5 5 4 C2 domain DUF2404 PF10296.4 CCC71162.1 - 0.0095 16.0 0.2 0.38 10.9 0.0 3.3 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) PA28_beta PF02252.13 CCC71162.1 - 0.022 14.2 0.0 0.078 12.4 0.0 1.9 2 0 0 2 2 2 0 Proteasome activator pa28 beta subunit MscS_porin PF12795.2 CCC71162.1 - 0.15 11.3 9.1 0.39 9.9 6.3 1.6 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Sec20 PF03908.8 CCC71162.1 - 0.39 10.4 3.9 6 6.6 1.5 2.8 2 0 0 2 2 2 0 Sec20 Snapin_Pallidin PF14712.1 CCC71163.1 - 2.4e-05 24.5 4.3 3.5e-05 24.0 3.0 1.3 1 0 0 1 1 1 1 Snapin/Pallidin LOH1CR12 PF10158.4 CCC71163.1 - 0.0019 17.9 0.6 0.0023 17.7 0.4 1.2 1 0 0 1 1 1 1 Tumour suppressor protein Filament PF00038.16 CCC71163.1 - 0.0027 17.2 2.1 0.0029 17.1 1.4 1.0 1 0 0 1 1 1 1 Intermediate filament protein TPR_MLP1_2 PF07926.7 CCC71163.1 - 0.013 15.1 2.5 0.018 14.7 1.7 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein YscO PF07321.7 CCC71163.1 - 0.015 15.0 0.6 0.02 14.7 0.4 1.2 1 0 0 1 1 1 0 Type III secretion protein YscO Herpes_U30 PF04523.8 CCC71163.1 - 0.025 12.0 1.0 0.029 11.8 0.7 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 Reo_sigmaC PF04582.7 CCC71163.1 - 0.073 12.2 0.5 0.075 12.2 0.4 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Sec8_exocyst PF04048.9 CCC71163.1 - 0.088 12.4 2.2 0.1 12.2 1.6 1.1 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain DASH_Dad3 PF08656.5 CCC71163.1 - 0.77 9.4 5.3 8.9 6.0 3.2 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad3 EMP24_GP25L PF01105.19 CCC71163.1 - 1.2 8.7 4.4 3.2 7.4 0.2 2.0 1 1 1 2 2 2 0 emp24/gp25L/p24 family/GOLD Mito_carr PF00153.22 CCC71164.1 - 6.6e-62 205.2 4.0 3e-20 71.7 0.2 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 CCC71164.1 - 4.5e-14 52.3 4.8 3e-10 40.0 1.3 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 CCC71164.1 - 7.4e-13 47.2 2.3 0.0016 18.1 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 CCC71164.1 - 1.6e-12 45.7 7.2 0.0019 17.3 0.2 4.9 5 0 0 5 5 5 3 EF hand EF-hand_5 PF13202.1 CCC71164.1 - 5.7e-09 34.9 8.4 0.015 14.6 0.1 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 CCC71164.1 - 6.5e-08 32.0 5.6 6.5e-07 28.8 1.2 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_9 PF14658.1 CCC71164.1 - 0.0016 18.2 0.0 1.3 9.0 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CCC71164.1 - 0.035 14.1 1.6 0.11 12.5 0.1 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DNA_mis_repair PF01119.14 CCC71165.1 - 1.4e-25 89.0 0.3 3.7e-25 87.7 0.1 1.8 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain MutL_C PF08676.6 CCC71165.1 - 2e-22 79.3 0.0 4.1e-22 78.3 0.0 1.5 1 0 0 1 1 1 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 CCC71165.1 - 1.1e-10 41.2 0.0 3.3e-10 39.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 CCC71165.1 - 4.5e-10 39.2 0.0 1.1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Flocculin PF00624.13 CCC71167.1 - 1.5e-10 40.6 6.8 1.5e-10 40.6 4.7 9.4 11 0 0 11 11 11 1 Flocculin repeat Ribosomal_S13 PF00416.17 CCC71168.1 - 3e-25 88.7 0.2 3.7e-25 88.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CCC71168.1 - 0.0033 16.0 0.0 0.0038 15.8 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) IMS_HHH PF11798.3 CCC71168.1 - 0.019 14.9 0.1 0.077 13.0 0.0 2.0 2 0 0 2 2 2 0 IMS family HHH motif EOS1 PF12326.3 CCC71169.1 - 2.3e-67 225.2 9.6 2.3e-67 225.2 6.7 2.1 2 1 0 2 2 2 1 N-glycosylation protein Med2 PF11214.3 CCC71169.1 - 0.025 14.6 1.2 0.66 10.0 0.2 2.8 3 0 0 3 3 3 0 Mediator complex subunit 2 SR-25 PF10500.4 CCC71169.1 - 0.046 13.1 9.9 0.073 12.5 6.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tropomyosin_1 PF12718.2 CCC71170.1 - 2.7e-47 160.2 57.5 5.1e-31 107.4 26.5 2.1 1 1 1 2 2 2 2 Tropomyosin like Tropomyosin PF00261.15 CCC71170.1 - 4.6e-10 38.9 49.5 7.7e-06 25.1 13.6 2.1 1 1 1 2 2 2 2 Tropomyosin KLRAQ PF10205.4 CCC71170.1 - 1.7e-07 31.2 33.5 0.00086 19.3 4.1 4.0 1 1 3 4 4 4 2 Predicted coiled-coil domain-containing protein ADIP PF11559.3 CCC71170.1 - 8.5e-07 28.9 44.0 0.00036 20.4 9.5 3.1 1 1 2 3 3 3 2 Afadin- and alpha -actinin-Binding Filament PF00038.16 CCC71170.1 - 2.2e-06 27.4 41.1 3.2e-06 26.8 28.5 1.4 1 0 0 1 1 1 1 Intermediate filament protein DUF3450 PF11932.3 CCC71170.1 - 1.7e-05 24.2 37.4 0.059 12.6 5.8 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3450) DUF4600 PF15372.1 CCC71170.1 - 3.5e-05 24.0 38.5 0.013 15.6 12.4 3.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4600) TMF_DNA_bd PF12329.3 CCC71170.1 - 6.1e-05 22.7 64.3 0.023 14.4 10.7 4.1 1 1 3 4 4 4 3 TATA element modulatory factor 1 DNA binding ERM PF00769.14 CCC71170.1 - 8.4e-05 22.2 50.0 0.002 17.7 16.5 2.1 1 1 1 2 2 2 2 Ezrin/radixin/moesin family GAS PF13851.1 CCC71170.1 - 9.1e-05 21.7 50.9 0.096 11.8 22.1 3.0 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding WXG100 PF06013.7 CCC71170.1 - 0.00021 21.2 19.6 0.13 12.2 0.2 4.7 2 1 1 3 3 3 2 Proteins of 100 residues with WXG ATG16 PF08614.6 CCC71170.1 - 0.00024 21.0 47.4 0.098 12.4 14.3 3.0 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Atg14 PF10186.4 CCC71170.1 - 0.00048 19.1 38.1 0.015 14.3 5.8 2.7 1 1 1 2 2 2 2 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 CCC71170.1 - 0.00081 18.6 11.7 0.011 14.9 1.2 2.4 1 1 1 2 2 2 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 CCC71170.1 - 0.0016 17.0 38.8 0.0026 16.2 26.9 1.3 1 0 0 1 1 1 1 AAA domain Myosin_tail_1 PF01576.14 CCC71170.1 - 0.0019 16.0 52.8 0.09 10.4 6.6 1.8 1 1 0 1 1 1 1 Myosin tail bZIP_1 PF00170.16 CCC71170.1 - 0.0038 17.1 48.9 0.23 11.4 4.9 5.6 1 1 5 6 6 6 2 bZIP transcription factor NPV_P10 PF05531.7 CCC71170.1 - 0.0045 17.2 25.9 1.5 9.0 0.0 4.7 1 1 3 4 4 4 1 Nucleopolyhedrovirus P10 protein DUF3287 PF11690.3 CCC71170.1 - 0.0046 17.0 2.1 0.0046 17.0 1.5 3.4 1 1 2 3 3 3 1 Protein of unknown function (DUF3287) DUF3584 PF12128.3 CCC71170.1 - 0.0056 14.0 39.1 0.0067 13.8 27.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Prefoldin_2 PF01920.15 CCC71170.1 - 0.0065 16.2 57.9 0.17 11.6 5.9 5.2 2 2 3 5 5 5 2 Prefoldin subunit LPP PF04728.8 CCC71170.1 - 0.0075 16.0 11.0 2 8.2 0.1 4.0 3 1 0 3 3 3 1 Lipoprotein leucine-zipper FTA4 PF13093.1 CCC71170.1 - 0.0079 15.6 6.2 0.0079 15.6 4.3 2.6 2 1 0 2 2 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4164 PF13747.1 CCC71170.1 - 0.0084 16.2 8.8 0.0084 16.2 6.1 3.3 1 1 2 3 3 3 1 Domain of unknown function (DUF4164) EzrA PF06160.7 CCC71170.1 - 0.0093 14.2 41.4 0.013 13.6 25.2 2.0 1 1 1 2 2 2 1 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 CCC71170.1 - 0.012 15.4 54.9 0.61 9.9 24.8 3.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.10 CCC71170.1 - 0.025 14.3 4.9 0.025 14.3 3.4 6.1 3 2 3 6 6 5 0 Basic region leucine zipper MbeD_MobD PF04899.7 CCC71170.1 - 0.031 14.1 0.8 0.031 14.1 0.5 4.0 3 1 1 4 4 4 0 MbeD/MobD like MscS_porin PF12795.2 CCC71170.1 - 0.035 13.4 38.8 0.74 9.0 2.7 2.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain IncA PF04156.9 CCC71170.1 - 0.041 13.4 52.1 0.15 11.6 14.0 3.0 1 1 2 3 3 3 0 IncA protein TPR_MLP1_2 PF07926.7 CCC71170.1 - 0.044 13.5 54.7 6.7 6.4 9.4 3.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DivIVA PF05103.8 CCC71170.1 - 0.048 13.7 43.5 0.24 11.4 10.9 3.9 1 1 3 4 4 4 0 DivIVA protein Laminin_II PF06009.7 CCC71170.1 - 0.05 13.3 34.1 0.78 9.4 4.7 3.3 1 1 2 3 3 3 0 Laminin Domain II BLOC1_2 PF10046.4 CCC71170.1 - 0.052 13.6 40.2 0.38 10.9 10.9 3.9 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 CCC71170.1 - 0.053 12.5 54.3 0.12 11.3 21.2 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF1664 PF07889.7 CCC71170.1 - 0.075 12.8 27.1 0.058 13.2 4.5 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) CCDC155 PF14662.1 CCC71170.1 - 0.091 12.3 50.1 0.39 10.3 7.5 2.9 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 DUF869 PF05911.6 CCC71170.1 - 0.12 10.5 43.7 0.3 9.2 13.8 2.1 1 1 1 2 2 2 0 Plant protein of unknown function (DUF869) DUF4201 PF13870.1 CCC71170.1 - 0.14 11.5 44.1 0.61 9.4 22.8 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Ax_dynein_light PF10211.4 CCC71170.1 - 0.17 11.7 48.4 0.71 9.6 6.5 3.5 2 1 1 3 3 2 0 Axonemal dynein light chain Snapin_Pallidin PF14712.1 CCC71170.1 - 0.23 11.8 34.3 0.066 13.5 8.8 4.2 1 1 3 4 4 4 0 Snapin/Pallidin Mod_r PF07200.8 CCC71170.1 - 0.28 11.0 42.6 7.9 6.3 1.8 3.9 1 1 2 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF479 PF04336.7 CCC71170.1 - 0.38 10.8 9.5 0.12 12.5 0.5 3.2 2 1 0 2 2 2 0 Protein of unknown function, DUF479 TBPIP PF07106.8 CCC71170.1 - 0.39 10.2 48.1 1.5 8.3 17.7 3.5 1 1 3 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fib_alpha PF08702.5 CCC71170.1 - 0.43 10.7 32.6 0.76 9.9 4.9 3.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF972 PF06156.8 CCC71170.1 - 0.5 10.7 42.6 0.62 10.4 7.1 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 CCC71170.1 - 0.59 10.0 51.5 0.71 9.8 15.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Taxilin PF09728.4 CCC71170.1 - 1.1 8.2 46.3 0.019 14.0 7.0 2.3 1 1 1 2 2 2 0 Myosin-like coiled-coil protein PilJ PF13675.1 CCC71170.1 - 1.4 9.2 16.8 1.6 9.0 1.0 3.2 1 1 2 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term HOOK PF05622.7 CCC71170.1 - 1.5 6.5 42.2 2.1 6.0 29.3 1.2 1 0 0 1 1 1 0 HOOK protein DUF904 PF06005.7 CCC71170.1 - 1.8 8.9 58.7 8.2e+03 -2.9 13.1 5.1 1 1 1 2 2 0 0 Protein of unknown function (DUF904) DivIC PF04977.10 CCC71170.1 - 1.8 8.1 53.9 0.16 11.4 5.0 5.3 2 2 3 5 5 5 0 Septum formation initiator DUF4559 PF15112.1 CCC71170.1 - 2.1 7.4 31.6 1.5 7.9 19.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) IFT57 PF10498.4 CCC71170.1 - 2.2 6.9 38.9 11 4.5 21.0 3.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Rootletin PF15035.1 CCC71170.1 - 2.6 7.9 46.0 0.85 9.5 15.9 3.0 1 1 2 3 3 3 0 Ciliary rootlet component, centrosome cohesion Mnd1 PF03962.10 CCC71170.1 - 3.1 7.4 46.5 3.9 7.1 9.0 3.1 1 1 2 3 3 3 0 Mnd1 family Laminin_I PF06008.9 CCC71170.1 - 3.2 7.0 39.6 4.5 6.5 27.4 1.3 1 0 0 1 1 1 0 Laminin Domain I Peptidase_S10 PF00450.17 CCC71170.1 - 3.3 6.7 14.4 6.9 5.7 10.0 1.6 1 1 0 1 1 1 0 Serine carboxypeptidase AAA_27 PF13514.1 CCC71170.1 - 3.3 5.2 36.4 15 3.0 25.2 1.9 1 1 0 1 1 1 0 AAA domain Spc7 PF08317.6 CCC71170.1 - 3.6 6.1 47.4 2.9 6.4 7.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein PspA_IM30 PF04012.7 CCC71170.1 - 3.7 6.8 38.9 2.1 7.6 12.5 2.7 1 1 1 2 2 2 0 PspA/IM30 family MCPsignal PF00015.16 CCC71170.1 - 3.9 6.9 15.6 0.69 9.4 2.1 2.3 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain MAD PF05557.8 CCC71170.1 - 4.1 5.3 47.7 7.9 4.4 33.0 1.5 1 1 0 1 1 1 0 Mitotic checkpoint protein Striatin PF08232.7 CCC71170.1 - 4.3 7.6 36.9 43 4.4 3.1 3.1 1 1 2 3 3 3 0 Striatin family Seryl_tRNA_N PF02403.17 CCC71170.1 - 4.9 7.2 46.7 0.093 12.7 11.0 3.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Syntaxin PF00804.20 CCC71170.1 - 5.5 7.2 38.4 3.3 7.9 4.8 3.5 1 1 2 3 3 3 0 Syntaxin DUF3552 PF12072.3 CCC71170.1 - 5.7 6.0 50.1 2.6 7.2 16.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3552) Lectin_N PF03954.9 CCC71170.1 - 6.7 6.1 20.3 6.9 6.0 5.2 3.1 1 1 2 3 3 3 0 Hepatic lectin, N-terminal domain TelA PF05816.6 CCC71170.1 - 7.5 5.1 33.0 1.1 7.9 0.0 3.0 1 1 2 3 3 3 0 Toxic anion resistance protein (TelA) Lebercilin PF15619.1 CCC71170.1 - 8.7 5.7 46.9 1.4e+02 1.7 32.0 2.3 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DnaJ PF00226.26 CCC71172.1 - 2.9e-22 78.1 2.7 5.6e-22 77.2 1.9 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCC71172.1 - 9.5e-14 51.0 0.6 1.1e-12 47.6 0.0 2.4 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCC71172.1 - 8.7e-11 41.7 15.1 2.1e-10 40.4 10.5 1.7 1 0 0 1 1 1 1 DnaJ central domain Gag_p17 PF00540.13 CCC71172.1 - 0.043 13.5 0.1 0.085 12.6 0.1 1.4 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) Nanovirus_coat PF04660.7 CCC71172.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Nanovirus coat protein U1snRNP70_N PF12220.3 CCC71172.1 - 7.6 6.9 9.6 5.7 7.3 1.4 2.5 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal zf-RING_3 PF14369.1 CCC71172.1 - 8.2 6.5 12.6 0.2 11.7 1.0 3.3 2 1 1 3 3 3 0 zinc-finger DUF1752 PF08550.5 CCC71173.1 - 1.4e-10 40.5 0.5 3.6e-10 39.2 0.4 1.8 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Brix PF04427.13 CCC71174.1 - 8.3e-48 162.5 0.2 1.1e-47 162.2 0.1 1.1 1 0 0 1 1 1 1 Brix domain RNase_HII PF01351.13 CCC71176.1 - 1.5e-60 204.2 0.0 1.8e-60 203.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII 2-oxoacid_dh PF00198.18 CCC71177.1 - 2.7e-74 249.3 0.1 4.2e-74 248.6 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 CCC71177.1 - 1.6e-17 62.8 0.2 6.7e-17 60.8 0.0 2.1 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 CCC71177.1 - 1.9e-14 53.0 0.3 4e-14 51.9 0.2 1.6 1 0 0 1 1 1 1 e3 binding domain DUF3614 PF12267.3 CCC71177.1 - 0.2 11.9 0.8 0.72 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) Tom7 PF08038.7 CCC71178.1 - 2.5e-20 71.6 0.1 3.2e-20 71.2 0.1 1.1 1 0 0 1 1 1 1 TOM7 family NUMOD3 PF07460.6 CCC71178.1 - 0.072 12.9 0.0 0.096 12.5 0.0 1.1 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) Ribosomal_L13 PF00572.13 CCC71179.1 - 2.5e-26 92.2 0.0 4.8e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L13 Fork_head PF00250.13 CCC71180.1 - 2.9e-36 123.3 0.4 7.4e-36 122.0 0.3 1.7 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 CCC71180.1 - 2e-12 47.0 0.8 7.7e-12 45.1 0.0 2.5 3 0 0 3 3 3 1 FHA domain MMS19_C PF12460.3 CCC71181.1 - 1.4e-94 317.1 19.3 1.4e-94 317.1 13.4 2.4 2 1 0 2 2 2 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 CCC71181.1 - 2.5e-90 302.2 11.3 4.4e-87 291.6 1.9 4.8 4 0 0 4 4 4 2 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.17 CCC71181.1 - 7e-05 22.5 4.0 0.025 14.6 0.0 5.0 6 0 0 6 6 6 1 HEAT repeat Ipi1_N PF12333.3 CCC71181.1 - 0.00023 21.0 5.2 4.4 7.3 0.0 5.2 5 0 0 5 5 5 2 Rix1 complex component involved in 60S ribosome maturation HEAT_2 PF13646.1 CCC71181.1 - 0.0013 18.9 0.0 7.4 6.9 0.0 4.2 3 2 1 5 5 5 2 HEAT repeats YobH PF13996.1 CCC71181.1 - 0.016 15.1 0.0 0.042 13.7 0.0 1.6 1 0 0 1 1 1 0 YobH-like protein HEAT_EZ PF13513.1 CCC71181.1 - 0.75 10.3 2.5 2.4 8.7 0.0 3.2 4 0 0 4 4 4 0 HEAT-like repeat DUF1018 PF06252.7 CCC71182.1 - 0.059 13.8 11.8 0.038 14.5 6.7 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1018) SLAC1 PF03595.12 CCC71183.1 - 7.5e-79 264.7 35.6 8.6e-79 264.5 24.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel SUN PF03856.8 CCC71184.1 - 2.8e-105 351.1 15.0 4.3e-105 350.4 10.4 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) Mucin PF01456.12 CCC71184.1 - 0.81 9.4 25.4 1.5 8.5 17.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 CCC71184.1 - 0.99 8.5 15.1 1.3 8.1 10.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Macoilin PF09726.4 CCC71184.1 - 1.4 7.1 4.8 1.5 6.9 3.3 1.0 1 0 0 1 1 1 0 Transmembrane protein MFS_1 PF07690.11 CCC71186.1 - 1.7e-37 128.9 21.4 1.7e-37 128.9 14.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCC71186.1 - 2.1e-17 62.8 16.0 2.3e-16 59.4 5.7 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter DUF791 PF05631.9 CCC71186.1 - 7.9e-05 21.5 0.1 0.00014 20.7 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF791) TRI12 PF06609.8 CCC71186.1 - 0.00036 18.8 4.2 0.00056 18.2 2.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ESSS PF10183.4 CCC71186.1 - 0.0058 17.0 3.1 2.6 8.4 0.0 3.1 3 0 0 3 3 3 2 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) MFS_1_like PF12832.2 CCC71186.1 - 0.018 14.8 1.4 0.11 12.2 0.0 2.9 3 0 0 3 3 3 0 MFS_1 like family SHR3_chaperone PF08229.6 CCC71186.1 - 0.046 12.6 0.0 0.1 11.5 0.0 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 DUF3353 PF11833.3 CCC71186.1 - 0.22 10.9 5.0 0.92 8.9 2.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) DUF788 PF05620.6 CCC71186.1 - 0.33 10.8 1.7 4.3 7.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF788) MFS_3 PF05977.8 CCC71186.1 - 0.36 8.8 4.9 0.63 8.0 3.4 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector DnaJ PF00226.26 CCC71187.1 - 8.8e-27 92.6 0.6 1.6e-26 91.8 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 CCC71187.1 - 1.5e-20 72.8 0.4 9.8e-18 63.8 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 CCC71187.1 - 6.9e-14 51.6 16.7 1.2e-13 50.9 11.6 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 CCC71187.1 - 0.014 15.1 10.5 0.15 11.7 1.2 2.3 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Methyltransf_31 PF13847.1 CCC71188.1 - 6.9e-12 45.1 0.0 1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCC71188.1 - 6.2e-11 42.3 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCC71188.1 - 2.5e-10 39.9 0.0 3.9e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CCC71188.1 - 7e-09 36.2 0.0 1.2e-08 35.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC71188.1 - 7.2e-08 32.7 0.0 1.4e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 CCC71188.1 - 6.8e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 CCC71188.1 - 3.6e-05 23.2 0.0 6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 N6_Mtase PF02384.11 CCC71188.1 - 0.00011 21.4 0.0 0.00014 21.0 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_32 PF13679.1 CCC71188.1 - 0.00061 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCC71188.1 - 0.0016 17.6 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) AviRa PF11599.3 CCC71188.1 - 0.01 14.8 0.2 0.022 13.7 0.0 1.6 2 1 0 2 2 2 0 RRNA methyltransferase AviRa Methyltransf_12 PF08242.7 CCC71188.1 - 0.011 16.1 0.0 0.019 15.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CCC71188.1 - 0.014 14.4 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TehB PF03848.9 CCC71188.1 - 0.018 14.2 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_11 PF08241.7 CCC71188.1 - 0.057 13.9 0.0 0.13 12.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Gcd10p PF04189.8 CCC71189.1 - 7.2e-102 340.5 0.9 1e-101 340.0 0.6 1.2 1 0 0 1 1 1 1 Gcd10p family Nol1_Nop2_Fmu PF01189.12 CCC71190.1 - 2.1e-109 365.2 0.0 3.4e-109 364.6 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family FtsJ PF01728.14 CCC71190.1 - 0.00096 19.1 0.1 0.0021 18.0 0.1 1.8 1 1 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.11 CCC71190.1 - 0.0012 18.4 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 CCC71190.1 - 0.0039 16.7 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Aldo_ket_red PF00248.16 CCC71191.1 - 4.1e-44 150.5 0.0 5.3e-44 150.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Actin PF00022.14 CCC71192.1 - 1e-44 152.5 0.0 9.9e-32 109.8 0.0 2.3 2 0 0 2 2 2 2 Actin Y_phosphatase2 PF03162.8 CCC71194.1 - 9.6e-54 181.1 0.0 1.2e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCC71194.1 - 4.1e-06 27.1 0.0 2.7e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Tyrosine phosphatase family Vac7 PF12751.2 CCC71195.1 - 1.7e-24 86.3 10.4 4e-19 68.7 0.2 4.2 2 2 2 4 4 4 2 Vacuolar segregation subunit 7 DSPc PF00782.15 CCC71196.1 - 2.5e-36 124.1 0.0 5.2e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCC71196.1 - 0.00044 19.6 0.0 0.001 18.4 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 CCC71196.1 - 0.0073 16.3 0.1 0.032 14.2 0.0 2.0 2 1 0 2 2 2 1 Inositol hexakisphosphate DSPn PF14671.1 CCC71196.1 - 0.028 14.3 0.1 0.069 13.1 0.0 1.6 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half COG5 PF10392.4 CCC71197.1 - 7.1e-41 139.2 1.5 7.1e-41 139.2 1.0 3.1 1 1 2 4 4 4 1 Golgi transport complex subunit 5 DUF2011 PF09428.5 CCC71198.1 - 8.4e-33 113.0 13.8 1.3e-32 112.4 9.6 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) Sec23_trunk PF04811.10 CCC71199.1 - 6e-66 222.2 0.3 1.2e-65 221.2 0.0 1.6 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCC71199.1 - 1.7e-24 85.2 0.1 4.4e-24 83.8 0.0 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 CCC71199.1 - 5.8e-17 60.9 7.2 1.2e-16 59.9 5.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 CCC71199.1 - 8.3e-15 55.0 0.2 2.5e-14 53.5 0.1 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 CCC71199.1 - 2.5e-11 43.1 1.8 3.4e-11 42.6 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat zf-RanBP PF00641.13 CCC71199.1 - 0.091 11.8 0.5 0.18 10.9 0.3 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others UQ_con PF00179.21 CCC71200.1 - 9.6e-39 132.0 0.1 1.3e-38 131.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 CCC71200.1 - 0.00066 19.5 0.1 0.0012 18.7 0.0 1.7 1 1 0 1 1 1 1 RWD domain TFIIA PF03153.8 CCC71200.1 - 5.2 6.8 18.8 6.8 6.4 13.0 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Alpha-amylase_C PF02806.13 CCC71201.1 - 1.4e-26 92.4 0.3 5.5e-26 90.5 0.1 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 CCC71201.1 - 9.8e-17 61.3 0.2 9.8e-17 61.3 0.2 3.4 4 1 0 4 4 4 1 Alpha amylase, catalytic domain CBM_48 PF02922.13 CCC71201.1 - 6e-14 51.8 0.1 1.5e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF2373 PF10180.4 CCC71202.1 - 0.028 13.9 0.1 0.063 12.8 0.1 1.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2373) DUF512 PF04459.7 CCC71202.1 - 0.051 12.6 0.2 0.067 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF512) DUF2373 PF10180.4 CCC71203.1 - 3.4e-28 96.9 0.9 5.9e-28 96.1 0.6 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) CENP-B_dimeris PF09026.5 CCC71203.1 - 0.19 11.9 4.6 0.39 10.9 3.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain HAD PF12710.2 CCC71204.1 - 2.8e-08 34.1 0.0 4.1e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGK PF00162.14 CCC71205.1 - 4.7e-152 506.0 0.1 5.3e-152 505.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.6 CCC71205.1 - 0.018 14.4 0.6 0.63 9.4 0.0 2.6 2 1 1 3 3 3 0 Propionate catabolism activator Grp1_Fun34_YaaH PF01184.14 CCC71206.1 - 2e-92 308.2 17.9 2.4e-92 307.9 12.4 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF997 PF06196.7 CCC71206.1 - 0.087 12.3 3.5 0.65 9.5 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF997) Rad9 PF04139.8 CCC71207.1 - 5.2e-11 42.1 1.5 3.8e-05 22.9 0.2 2.2 2 0 0 2 2 2 2 Rad9 SBP_bac_10 PF07596.6 CCC71207.1 - 0.036 14.0 0.4 0.063 13.2 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) PRA1 PF03208.14 CCC71208.1 - 1.9e-39 134.4 1.7 2.3e-39 134.2 1.2 1.1 1 0 0 1 1 1 1 PRA1 family protein IncA PF04156.9 CCC71208.1 - 0.075 12.6 0.1 0.075 12.6 0.1 2.6 3 0 0 3 3 3 0 IncA protein DUF4190 PF13828.1 CCC71208.1 - 4.5 6.8 6.6 1.5 8.4 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Peptidase_M1 PF01433.15 CCC71209.1 - 9.2e-81 271.8 0.1 1.3e-80 271.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 CCC71209.1 - 4.2e-46 156.0 0.4 8.3e-46 155.1 0.3 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 CCC71209.1 - 1.9e-15 57.0 0.0 3e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M64 PF09471.5 CCC71209.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 IgA Peptidase M64 Peptidase_M61 PF05299.7 CCC71209.1 - 0.22 11.5 2.0 1.5 8.8 1.4 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF2207 PF09972.4 CCC71210.1 - 0.054 12.0 1.3 0.078 11.5 0.9 1.2 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Sigma_reg_N PF13800.1 CCC71210.1 - 0.16 12.0 1.9 0.41 10.6 1.3 1.7 1 0 0 1 1 1 0 Sigma factor regulator N-terminal Glycos_transf_1 PF00534.15 CCC71211.1 - 6.7e-14 51.6 0.0 1.4e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 CCC71211.1 - 0.009 16.1 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Arm PF00514.18 CCC71212.1 - 8.4e-66 215.7 36.1 9.9e-12 44.2 0.0 11.2 12 0 0 12 12 12 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 CCC71212.1 - 3.5e-25 88.0 7.9 2.8e-07 30.7 0.1 7.7 2 2 4 6 6 6 6 HEAT repeats HEAT_EZ PF13513.1 CCC71212.1 - 1.6e-16 60.2 12.7 0.0005 20.4 0.3 8.2 6 1 3 9 9 9 4 HEAT-like repeat HEAT PF02985.17 CCC71212.1 - 2.2e-15 55.2 23.1 0.053 13.6 0.1 11.2 12 0 0 12 12 12 3 HEAT repeat Adaptin_N PF01602.15 CCC71212.1 - 6.2e-12 44.6 12.8 1.8e-07 29.9 1.2 2.9 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 CCC71212.1 - 1.3e-11 43.2 3.7 6.5e-06 24.3 0.2 3.0 1 1 2 3 3 3 2 Kinesin-associated protein (KAP) Arm_2 PF04826.8 CCC71212.1 - 6e-10 38.6 13.0 0.00028 20.0 0.3 4.2 4 1 1 5 5 5 3 Armadillo-like Vac14_Fab1_bd PF12755.2 CCC71212.1 - 8.1e-05 22.9 1.2 0.89 9.9 0.0 4.0 3 1 0 3 3 3 2 Vacuolar 14 Fab1-binding region V-ATPase_H_N PF03224.9 CCC71212.1 - 9.9e-05 21.5 5.9 0.052 12.6 3.2 3.2 1 1 1 2 2 2 1 V-ATPase subunit H DUF2454 PF10521.4 CCC71212.1 - 0.00012 21.1 1.7 0.0045 16.0 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2454) RIX1 PF08167.7 CCC71212.1 - 0.027 14.1 1.7 0.14 11.8 0.1 2.9 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis DUF1981 PF09324.5 CCC71212.1 - 0.055 12.9 0.2 37 3.9 0.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1981) DUF4611 PF15387.1 CCC71212.1 - 0.092 12.9 1.5 6 7.0 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) OapA PF04225.7 CCC71212.1 - 0.14 12.0 0.8 4.9 7.1 0.2 2.6 1 1 1 2 2 2 0 Opacity-associated protein A LysM-like domain YjeF_N PF03853.10 CCC71213.1 - 5.6e-19 68.3 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 CCC71213.1 - 0.0017 18.8 13.0 0.0017 18.8 9.0 3.0 3 0 0 3 3 3 1 FDF domain DUF4376 PF14301.1 CCC71213.1 - 0.9 9.6 5.9 33 4.6 4.1 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4376) eRF1_2 PF03464.10 CCC71214.1 - 3.1e-31 108.4 0.1 6.1e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CCC71214.1 - 9.3e-25 87.0 0.1 2.7e-24 85.6 0.0 1.8 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CCC71214.1 - 1e-10 41.3 0.1 1.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 EST1 PF10374.4 CCC71214.1 - 0.45 10.4 6.7 0.099 12.6 1.1 2.2 2 1 0 2 2 2 0 Telomerase activating protein Est1 Septin PF00735.13 CCC71215.1 - 4.3e-103 344.1 1.7 5.1e-103 343.9 1.2 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 CCC71215.1 - 4.2e-09 36.3 0.2 6.7e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCC71215.1 - 1.8e-07 30.4 0.0 3.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 CCC71215.1 - 1.5e-06 27.7 0.7 2.6e-05 23.7 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 CCC71215.1 - 8.1e-06 25.7 1.7 0.067 13.0 0.2 2.5 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 CCC71215.1 - 9.6e-06 24.8 0.3 1.8e-05 23.9 0.2 1.6 1 1 0 1 1 1 1 AIG1 family AAA_16 PF13191.1 CCC71215.1 - 0.0016 18.4 0.1 0.0024 17.8 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 CCC71215.1 - 0.0016 17.9 0.0 0.0034 16.8 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_24 PF13479.1 CCC71215.1 - 0.0027 17.3 0.0 0.0055 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 CCC71215.1 - 0.0028 18.1 0.2 0.0089 16.5 0.1 1.8 1 1 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 CCC71215.1 - 0.0034 17.5 0.1 0.011 15.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 CCC71215.1 - 0.0045 16.4 0.3 0.0081 15.6 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain AAA_33 PF13671.1 CCC71215.1 - 0.0048 16.7 0.2 0.044 13.6 0.1 2.5 3 1 0 3 3 3 1 AAA domain IIGP PF05049.8 CCC71215.1 - 0.0092 14.8 0.5 0.03 13.1 0.2 1.9 1 1 1 2 2 2 1 Interferon-inducible GTPase (IIGP) AAA_14 PF13173.1 CCC71215.1 - 0.012 15.5 0.3 0.037 13.9 0.0 2.0 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCC71215.1 - 0.012 15.8 2.4 0.024 14.9 1.5 1.7 1 1 0 1 1 1 0 ABC transporter Gtr1_RagA PF04670.7 CCC71215.1 - 0.013 14.6 0.8 0.1 11.7 0.6 2.1 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MobB PF03205.9 CCC71215.1 - 0.016 14.9 0.1 0.1 12.2 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 CCC71215.1 - 0.019 14.5 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 CCC71215.1 - 0.035 12.9 0.1 0.051 12.4 0.1 1.4 1 1 0 1 1 1 0 NB-ARC domain PduV-EutP PF10662.4 CCC71215.1 - 0.052 13.0 0.2 0.86 9.0 0.1 2.4 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 CCC71215.1 - 0.066 12.4 1.7 2.1 7.6 0.8 2.5 2 1 0 2 2 2 0 Ferrous iron transport protein B Flavodoxin_1 PF00258.20 CCC71216.1 - 2.6e-12 46.9 0.2 7.3e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Flavodoxin FMN_red PF03358.10 CCC71216.1 - 1e-06 28.3 0.2 3.2e-06 26.7 0.0 2.0 2 2 1 3 3 3 1 NADPH-dependent FMN reductase Flavodoxin_5 PF12724.2 CCC71216.1 - 0.0081 16.1 0.0 0.038 13.9 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_2 PF02525.12 CCC71216.1 - 0.0092 15.5 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin-like fold DUF4611 PF15387.1 CCC71218.1 - 0.029 14.5 3.8 27 5.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CN_hydrolase PF00795.17 CCC71219.1 - 8.2e-32 110.0 0.0 1.2e-31 109.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Gsf2 PF11055.3 CCC71220.1 - 2.2e-166 553.0 1.0 2.7e-166 552.7 0.7 1.0 1 0 0 1 1 1 1 Glucose signalling factor 2 CPSF_A PF03178.10 CCC71221.1 - 4.7e-58 196.7 5.3 2.8e-55 187.6 0.3 2.6 2 0 0 2 2 2 2 CPSF A subunit region MMS1_N PF10433.4 CCC71221.1 - 6.8e-21 73.9 16.2 1.4e-20 72.9 11.2 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nucleoplasmin PF03066.10 CCC71221.1 - 1.2 8.6 15.5 4.7 6.7 0.1 2.5 2 0 0 2 2 2 0 Nucleoplasmin PBP1_TM PF14812.1 CCC71221.1 - 4 7.7 12.7 6.4 7.1 4.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.5 CCC71221.1 - 7 6.9 15.7 3.7 7.8 5.0 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Suc_Fer-like PF06999.7 CCC71222.1 - 9.7e-32 110.8 0.0 1.3e-31 110.4 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like GFO_IDH_MocA PF01408.17 CCC71223.1 - 6e-08 33.2 0.0 8.7e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 CCC71223.1 - 0.016 15.0 0.0 0.042 13.6 0.0 1.7 2 0 0 2 2 2 0 Oxidoreductase family, C-terminal alpha/beta domain SUR7 PF06687.7 CCC71224.1 - 2.3e-37 128.6 10.1 2.8e-37 128.3 7.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 CCC71224.1 - 2.5e-05 24.2 2.3 3.8e-05 23.6 1.6 1.3 1 0 0 1 1 1 1 Ca2+ regulator and membrane fusion protein Fig1 DUF3661 PF12400.3 CCC71224.1 - 0.068 13.2 4.6 0.14 12.2 3.2 1.5 1 0 0 1 1 1 0 Vaculolar membrane protein YjgP_YjgQ PF03739.9 CCC71224.1 - 0.14 10.8 5.7 0.22 10.1 3.9 1.4 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF1077 PF06417.7 CCC71224.1 - 0.42 9.9 3.6 1.8 7.9 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1077) DUF805 PF05656.9 CCC71224.1 - 8.4 6.2 11.8 1.5 8.6 5.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Thymidylate_kin PF02223.12 CCC71226.1 - 2.8e-46 157.2 0.0 3.2e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 CCC71226.1 - 0.0049 16.8 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 CCC71226.1 - 0.0073 16.6 0.5 0.018 15.3 0.0 1.8 1 1 1 2 2 2 1 AAA domain KTI12 PF08433.5 CCC71226.1 - 0.023 13.9 0.7 0.08 12.1 0.5 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 DUF643 PF04867.7 CCC71226.1 - 0.053 13.9 0.4 0.35 11.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF643) Kinase-PPPase PF03618.9 CCC71226.1 - 0.067 12.6 0.2 0.18 11.2 0.0 1.8 2 0 0 2 2 2 0 Kinase/pyrophosphorylase Clat_adaptor_s PF01217.15 CCC71227.1 - 2.1e-52 176.6 2.5 3.1e-50 169.6 1.7 2.0 1 1 0 1 1 1 1 Clathrin adaptor complex small chain AAA PF00004.24 CCC71228.1 - 1.9e-53 180.2 0.0 6e-44 149.4 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 CCC71228.1 - 1.4e-21 76.3 0.8 1.4e-21 76.3 0.5 2.3 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 CCC71228.1 - 3.3e-11 43.5 0.3 0.00012 22.1 0.0 3.4 3 1 1 4 4 3 2 AAA ATPase domain AAA_17 PF13207.1 CCC71228.1 - 5.3e-11 43.4 0.0 0.0001 23.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 CCC71228.1 - 7.8e-10 38.7 0.0 0.00014 21.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCC71228.1 - 3e-08 34.0 2.0 0.0006 20.1 0.0 3.6 4 0 0 4 4 2 2 AAA domain NACHT PF05729.7 CCC71228.1 - 1.3e-07 31.4 1.8 0.0089 15.7 0.1 4.6 4 1 0 4 4 4 2 NACHT domain AAA_22 PF13401.1 CCC71228.1 - 1e-06 28.8 0.7 0.25 11.4 0.0 4.5 3 2 0 3 3 3 2 AAA domain TIP49 PF06068.8 CCC71228.1 - 4.8e-06 25.5 0.1 0.042 12.5 0.0 2.8 3 0 0 3 3 3 2 TIP49 C-terminus IstB_IS21 PF01695.12 CCC71228.1 - 6.2e-06 25.7 0.1 0.07 12.5 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_33 PF13671.1 CCC71228.1 - 6.6e-06 26.0 0.0 0.17 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CCC71228.1 - 9.3e-06 25.4 0.0 0.11 12.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 CCC71228.1 - 1.4e-05 24.2 0.0 0.0027 16.7 0.0 2.7 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 CCC71228.1 - 1.9e-05 24.3 0.0 0.17 11.4 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 CCC71228.1 - 2.4e-05 23.5 0.0 0.24 10.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_19 PF13245.1 CCC71228.1 - 2.8e-05 23.7 0.0 0.15 11.7 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain Arch_ATPase PF01637.13 CCC71228.1 - 4.6e-05 23.2 0.3 0.1 12.3 0.0 3.6 2 1 1 3 3 3 1 Archaeal ATPase AAA_25 PF13481.1 CCC71228.1 - 4.6e-05 22.9 1.3 0.56 9.5 0.1 4.1 3 2 1 5 5 5 1 AAA domain AAA_2 PF07724.9 CCC71228.1 - 5.1e-05 23.2 0.0 0.01 15.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 CCC71228.1 - 0.00013 21.2 0.1 0.53 9.4 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 CCC71228.1 - 0.00014 21.5 0.0 0.21 11.2 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 CCC71228.1 - 0.00023 21.3 0.0 0.37 10.9 0.0 3.2 2 0 0 2 2 2 1 RNA helicase T2SE PF00437.15 CCC71228.1 - 0.00025 20.0 0.2 0.015 14.2 0.1 2.7 2 1 1 3 3 3 1 Type II/IV secretion system protein AAA_28 PF13521.1 CCC71228.1 - 0.00035 20.5 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 CCC71228.1 - 0.00039 19.5 0.0 0.4 9.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 CCC71228.1 - 0.00058 20.1 0.2 0.82 9.9 0.0 3.2 3 0 0 3 3 2 1 ABC transporter NB-ARC PF00931.17 CCC71228.1 - 0.00095 18.1 0.0 1.2 7.8 0.0 2.8 2 0 0 2 2 2 2 NB-ARC domain ATP_bind_1 PF03029.12 CCC71228.1 - 0.00096 18.7 0.0 0.0033 17.0 0.0 1.9 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 CCC71228.1 - 0.0026 17.4 0.0 0.17 11.5 0.0 2.5 2 0 0 2 2 2 1 NTPase cobW PF02492.14 CCC71228.1 - 0.0036 16.7 0.4 0.34 10.3 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.21 CCC71228.1 - 0.0036 16.7 0.0 6.5 6.1 0.0 3.6 3 1 0 4 4 3 0 Sigma-54 interaction domain KaiC PF06745.8 CCC71228.1 - 0.0052 15.9 0.1 3 6.8 0.0 2.7 2 0 0 2 2 2 1 KaiC AAA_11 PF13086.1 CCC71228.1 - 0.0057 16.2 2.3 0.066 12.7 0.0 3.1 4 0 0 4 4 3 1 AAA domain AAA_30 PF13604.1 CCC71228.1 - 0.0064 16.0 0.0 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CCC71228.1 - 0.0067 16.0 1.0 3.6 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 CCC71228.1 - 0.0087 15.5 0.0 0.12 11.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain KTI12 PF08433.5 CCC71228.1 - 0.015 14.4 1.3 0.72 9.0 0.0 2.9 3 0 0 3 3 3 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 CCC71228.1 - 0.017 14.7 0.0 6.6 6.3 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Cytidylate_kin2 PF13189.1 CCC71228.1 - 0.019 14.8 0.4 0.25 11.2 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase-like family AAA_31 PF13614.1 CCC71228.1 - 0.021 14.7 0.0 5 7.0 0.0 2.9 2 1 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 CCC71228.1 - 0.032 13.7 0.0 3.9 6.9 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 CCC71228.1 - 0.068 12.6 0.1 7.9 5.8 0.0 2.8 3 0 0 3 3 2 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 CCC71228.1 - 0.077 13.0 0.1 1.2 9.1 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain Pkinase PF00069.20 CCC71229.1 - 1.2e-41 142.6 0.1 2.7e-41 141.4 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71229.1 - 8.6e-17 61.0 0.0 1.7e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCC71229.1 - 0.0002 20.5 0.0 0.00037 19.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCC71229.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like LicD PF04991.8 CCC71230.1 - 2e-53 181.5 4.2 2e-53 181.5 2.9 2.9 3 1 0 3 3 3 1 LicD family FAT PF02259.18 CCC71231.1 - 3e-133 444.1 0.9 8e-133 442.7 0.0 2.2 2 0 0 2 2 2 1 FAT domain DUF3385 PF11865.3 CCC71231.1 - 1e-65 220.5 1.5 6.3e-65 217.9 0.3 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 CCC71231.1 - 5.6e-61 205.9 0.1 1.1e-60 205.0 0.1 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 CCC71231.1 - 3.1e-41 139.4 3.7 1e-40 137.8 0.3 3.3 3 0 0 3 3 3 1 Rapamycin binding domain FATC PF02260.15 CCC71231.1 - 1.4e-18 65.9 0.1 3.5e-18 64.7 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 CCC71231.1 - 5.9e-15 55.3 3.9 0.00073 19.7 0.1 8.6 5 2 4 9 9 9 4 HEAT repeats HEAT_EZ PF13513.1 CCC71231.1 - 1e-09 38.5 10.6 3.1e-05 24.3 0.0 7.7 8 1 1 9 9 9 2 HEAT-like repeat HEAT PF02985.17 CCC71231.1 - 3e-06 26.8 10.6 0.062 13.4 0.0 7.4 9 0 0 9 9 9 2 HEAT repeat Vac14_Fab1_bd PF12755.2 CCC71231.1 - 0.014 15.8 0.9 1.4 9.3 0.0 4.4 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Xpo1 PF08389.7 CCC71232.1 - 6.4e-32 110.5 9.0 6.8e-32 110.4 1.2 3.9 3 1 0 4 4 4 1 Exportin 1-like protein Ham1p_like PF01725.11 CCC71233.1 - 2.1e-49 167.5 0.0 2.3e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Ham1 family HEAT_2 PF13646.1 CCC71234.1 - 1.8e-39 133.8 0.5 3.4e-18 65.7 0.0 3.4 3 1 2 5 5 5 3 HEAT repeats HEAT_PBS PF03130.11 CCC71234.1 - 1.6e-22 77.6 0.9 5.5e-06 26.3 0.3 6.4 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.17 CCC71234.1 - 4.9e-13 47.9 1.3 0.059 13.4 0.0 5.7 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.1 CCC71234.1 - 9.1e-12 45.0 4.6 0.00046 20.5 0.3 4.7 4 1 1 5 5 5 3 HEAT-like repeat Arm PF00514.18 CCC71234.1 - 0.018 14.8 0.4 20 5.2 0.0 4.1 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat TPR_21 PF09976.4 CCC71234.1 - 0.038 13.9 0.6 0.1 12.5 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Adaptin_N PF01602.15 CCC71234.1 - 0.04 12.2 0.4 0.99 7.6 0.0 2.5 2 1 0 2 2 2 0 Adaptin N terminal region ATP_bind_1 PF03029.12 CCC71235.1 - 4.8e-85 284.8 0.1 7.1e-85 284.3 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 CCC71235.1 - 1.9e-07 30.6 0.1 5.6e-07 29.1 0.0 1.8 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain GTP_EFTU PF00009.22 CCC71235.1 - 6.7e-06 25.6 0.5 0.00013 21.4 0.3 2.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 CCC71235.1 - 9.3e-05 22.5 0.1 0.00046 20.3 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 CCC71235.1 - 9.3e-05 22.3 0.0 0.00024 20.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 CCC71235.1 - 0.00021 22.0 3.3 0.00039 21.2 0.0 2.4 2 1 0 2 2 1 1 AAA domain AAA_10 PF12846.2 CCC71235.1 - 0.00023 20.7 1.2 0.0023 17.4 0.9 2.1 1 1 0 1 1 1 1 AAA-like domain MMR_HSR1 PF01926.18 CCC71235.1 - 0.0003 20.7 0.1 0.0012 18.7 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.7 CCC71235.1 - 0.00041 20.0 0.0 0.0008 19.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ArgK PF03308.11 CCC71235.1 - 0.00068 18.4 0.0 0.38 9.4 0.0 2.4 2 0 0 2 2 2 2 ArgK protein PduV-EutP PF10662.4 CCC71235.1 - 0.00092 18.7 0.0 0.03 13.8 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 CCC71235.1 - 0.0029 17.3 0.6 0.035 13.8 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 CCC71235.1 - 0.0033 16.6 0.0 0.066 12.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B cobW PF02492.14 CCC71235.1 - 0.0039 16.6 0.1 0.029 13.8 0.0 2.3 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 CCC71235.1 - 0.0043 16.5 0.0 0.041 13.3 0.0 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 CCC71235.1 - 0.0054 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain ATP-synt_E PF05680.7 CCC71235.1 - 0.0072 16.2 1.3 0.017 15.0 0.9 1.6 1 0 0 1 1 1 1 ATP synthase E chain AAA_24 PF13479.1 CCC71235.1 - 0.0082 15.7 0.0 0.02 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 CCC71235.1 - 0.0084 16.6 0.1 0.78 10.2 0.1 2.7 1 1 0 1 1 1 1 Miro-like protein KTI12 PF08433.5 CCC71235.1 - 0.014 14.5 0.0 0.035 13.3 0.0 1.7 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Arf PF00025.16 CCC71235.1 - 0.016 14.4 0.0 1.2 8.3 0.0 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family PRK PF00485.13 CCC71235.1 - 0.042 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 CCC71235.1 - 0.043 13.3 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCC71235.1 - 0.051 13.8 0.0 0.051 13.8 0.0 2.9 3 1 0 3 3 1 0 AAA domain DUF258 PF03193.11 CCC71235.1 - 0.052 12.7 0.0 0.76 8.9 0.0 2.5 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Glyco_tranf_2_3 PF13641.1 CCC71235.1 - 0.057 13.2 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family 2 SRPRB PF09439.5 CCC71235.1 - 0.11 11.6 3.7 0.53 9.4 0.0 2.6 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit DUF87 PF01935.12 CCC71235.1 - 0.16 11.7 3.7 3 7.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF87 DUF106 PF01956.11 CCC71236.1 - 3.2e-56 189.4 1.7 3.9e-56 189.1 1.2 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 ABC_membrane PF00664.18 CCC71238.1 - 1.7e-89 299.9 40.7 4.1e-47 160.9 11.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 CCC71238.1 - 2.3e-64 215.8 0.6 2.8e-31 108.6 0.0 3.1 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 CCC71238.1 - 3.6e-17 62.3 0.0 1.2e-05 24.6 0.7 4.8 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 CCC71238.1 - 1.2e-09 38.5 8.8 0.0012 18.8 0.1 5.1 2 2 1 4 4 4 2 AAA domain AAA_10 PF12846.2 CCC71238.1 - 7.9e-09 35.3 1.7 0.00088 18.7 0.0 4.2 4 0 0 4 4 4 2 AAA-like domain DUF258 PF03193.11 CCC71238.1 - 6.6e-08 31.8 0.0 0.0085 15.2 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 CCC71238.1 - 7e-08 32.6 2.0 0.0087 16.1 0.2 3.9 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCC71238.1 - 1.6e-07 30.7 8.0 0.0021 17.5 0.0 3.3 4 0 0 4 4 3 2 P-loop containing region of AAA domain AAA_17 PF13207.1 CCC71238.1 - 2.9e-07 31.3 0.0 0.011 16.5 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCC71238.1 - 1e-06 29.0 0.1 0.11 12.8 0.0 4.1 4 0 0 4 4 4 2 AAA domain ABC_ATPase PF09818.4 CCC71238.1 - 1.7e-06 26.9 0.0 0.012 14.1 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 CCC71238.1 - 5.5e-06 26.5 0.0 0.099 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 CCC71238.1 - 7.8e-06 25.8 0.2 0.11 12.4 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_14 PF13173.1 CCC71238.1 - 0.00016 21.5 1.9 3.7 7.4 0.0 4.8 4 1 1 5 5 5 1 AAA domain DUF3987 PF13148.1 CCC71238.1 - 0.0002 20.0 0.0 0.072 11.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_23 PF13476.1 CCC71238.1 - 0.00026 21.4 5.3 0.38 11.0 0.1 3.4 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 CCC71238.1 - 0.00035 20.7 0.0 1 9.5 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_5 PF07728.9 CCC71238.1 - 0.00035 20.3 0.1 2 8.1 0.0 3.5 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) T2SE PF00437.15 CCC71238.1 - 0.00048 19.1 0.1 0.11 11.4 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_33 PF13671.1 CCC71238.1 - 0.00064 19.6 0.0 0.3 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 CCC71238.1 - 0.00088 18.4 0.0 0.17 10.9 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin DUF87 PF01935.12 CCC71238.1 - 0.00092 19.0 2.9 1.2 8.8 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function DUF87 APS_kinase PF01583.15 CCC71238.1 - 0.00099 18.7 0.2 0.49 10.0 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase MobB PF03205.9 CCC71238.1 - 0.0011 18.7 0.4 1.8 8.2 0.1 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 CCC71238.1 - 0.003 16.9 0.0 1.8 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_13 PF13166.1 CCC71238.1 - 0.0036 15.8 0.6 0.0036 15.8 0.4 3.4 3 1 1 4 4 4 1 AAA domain NB-ARC PF00931.17 CCC71238.1 - 0.0094 14.8 0.0 1.8 7.3 0.0 2.6 2 0 0 2 2 2 1 NB-ARC domain AAA_30 PF13604.1 CCC71238.1 - 0.015 14.9 0.0 2.2 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CCC71238.1 - 0.017 14.6 0.8 8.6 5.8 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PRK PF00485.13 CCC71238.1 - 0.019 14.5 0.0 0.67 9.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CbiA PF01656.18 CCC71238.1 - 0.019 14.3 0.1 0.13 11.6 0.0 2.2 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 CCC71238.1 - 0.036 13.7 1.9 3.5 7.2 0.1 2.8 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 CCC71238.1 - 0.044 14.2 0.4 18 5.8 0.0 3.0 3 0 0 3 3 2 0 Miro-like protein Arch_ATPase PF01637.13 CCC71238.1 - 0.13 11.9 4.8 7 6.2 0.0 4.5 4 1 1 5 5 5 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 CCC71238.1 - 0.17 11.3 0.1 12 5.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 CCC71238.1 - 0.36 10.2 3.6 5.8 6.3 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MSG PF02349.10 CCC71238.1 - 0.78 9.7 4.0 0.27 11.2 0.1 2.1 2 0 0 2 2 1 0 Major surface glycoprotein SbcCD_C PF13558.1 CCC71238.1 - 0.79 9.6 2.9 18 5.3 0.0 3.6 4 2 0 4 4 2 0 Putative exonuclease SbcCD, C subunit GATA PF00320.22 CCC71239.1 - 1e-13 50.3 5.5 1.9e-13 49.5 3.8 1.4 1 0 0 1 1 1 1 GATA zinc finger ThiF PF00899.16 CCC71240.1 - 1.5e-51 173.7 1.9 5e-32 110.5 0.0 2.8 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 CCC71240.1 - 1.4e-45 154.4 0.7 6.1e-45 152.4 0.0 2.4 3 0 0 3 3 3 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 CCC71240.1 - 1.3e-31 107.9 4.6 4.1e-23 80.7 0.2 2.8 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 CCC71240.1 - 2.4e-26 90.8 0.3 1e-20 72.7 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Gly_transf_sug PF04488.10 CCC71241.1 - 4.7e-12 46.2 0.0 1.7e-11 44.3 0.0 2.0 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif SRP_SPB PF02978.14 CCC71241.1 - 0.064 13.5 3.7 0.17 12.1 2.6 1.7 1 0 0 1 1 1 0 Signal peptide binding domain Septin PF00735.13 CCC71242.1 - 8.1e-107 356.4 0.0 8.1e-107 356.4 0.0 1.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 CCC71242.1 - 1.9e-08 34.2 0.0 4.4e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 CCC71242.1 - 3.6e-06 26.8 8.8 0.00021 21.1 0.2 3.1 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 CCC71242.1 - 2.2e-05 23.6 0.7 9.8e-05 21.5 0.5 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CCC71242.1 - 3.6e-05 22.9 0.1 3.6e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 AIG1 family ABC_tran PF00005.22 CCC71242.1 - 0.00048 20.4 1.4 0.0008 19.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 CCC71242.1 - 0.00074 19.9 0.1 0.0019 18.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein IIGP PF05049.8 CCC71242.1 - 0.0017 17.2 0.1 0.0031 16.3 0.1 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 CCC71242.1 - 0.0041 16.3 0.6 0.047 12.9 0.4 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_10 PF12846.2 CCC71242.1 - 0.0084 15.5 0.2 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 CCC71242.1 - 0.056 14.2 0.8 0.32 11.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 CCC71242.1 - 0.057 12.9 0.4 1.1 8.6 0.1 2.2 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IGPS PF00218.16 CCC71243.1 - 5.9e-90 300.7 0.1 7.7e-90 300.3 0.1 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 CCC71243.1 - 2.1e-53 180.6 0.1 3.3e-53 179.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 CCC71243.1 - 1.7e-10 40.7 0.0 3.6e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 QRPTase_C PF01729.14 CCC71243.1 - 0.00026 20.5 0.1 0.00081 18.9 0.1 1.8 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain Syja_N PF02383.13 CCC71244.1 - 2.7e-85 285.9 2.6 3.8e-85 285.4 1.8 1.2 1 0 0 1 1 1 1 SacI homology domain InaF-motif PF15018.1 CCC71244.1 - 0.0014 18.0 0.2 0.0014 18.0 0.2 1.9 2 0 0 2 2 2 1 TRP-interacting helix Ribosomal_L30 PF00327.15 CCC71245.1 - 2.9e-15 55.5 0.4 1.1e-14 53.7 0.3 2.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Peptidase_C1_2 PF03051.10 CCC71246.1 - 6.2e-156 519.3 0.6 7e-156 519.1 0.4 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 CCC71246.1 - 1.2e-06 28.5 0.0 0.019 14.8 0.0 2.4 2 0 0 2 2 2 2 Papain family cysteine protease DMRL_synthase PF00885.14 CCC71246.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 6,7-dimethyl-8-ribityllumazine synthase WD40 PF00400.27 CCC71247.1 - 7.1e-50 165.1 13.7 6.6e-12 44.8 0.0 7.5 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 CCC71247.1 - 6.7e-08 31.1 11.8 0.012 13.8 0.1 4.9 3 1 2 5 5 5 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 CCC71247.1 - 9.4e-07 27.4 0.1 7.4e-06 24.5 0.1 2.0 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 CCC71247.1 - 1.6e-05 23.8 3.0 0.25 10.0 0.0 4.0 1 1 1 3 3 3 2 Nup133 N terminal like eIF2A PF08662.6 CCC71247.1 - 0.0032 17.1 3.3 0.06 13.0 0.1 3.0 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 CCC71247.1 - 0.0046 15.9 0.3 2.8 6.7 0.0 3.2 1 1 1 3 3 3 2 Protein of unknown function (DUF1513) DUF3312 PF11768.3 CCC71247.1 - 0.0077 14.5 0.0 0.021 13.0 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3312) DnaJ PF00226.26 CCC71248.1 - 4e-23 80.9 0.8 5.8e-23 80.3 0.2 1.6 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 CCC71248.1 - 4e-22 77.9 0.6 3.2e-19 68.5 0.0 2.6 2 1 0 2 2 2 2 DnaJ C terminal domain Iso_dh PF00180.15 CCC71249.1 - 6.3e-64 216.1 0.0 7.4e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase HAD PF12710.2 CCC71250.1 - 5.2e-14 52.8 0.1 7.3e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 CCC71250.1 - 3.8e-05 22.9 0.0 0.00025 20.2 0.0 1.9 1 1 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 CCC71250.1 - 3.8e-05 23.9 0.0 0.00058 20.1 0.0 2.3 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 CCC71250.1 - 0.00042 19.7 0.0 0.0014 17.9 0.0 1.8 1 1 1 2 2 2 1 Pyrimidine 5'-nucleotidase (UMPH-1) DUF4326 PF14216.1 CCC71250.1 - 0.032 14.7 0.0 0.072 13.6 0.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4326) UPF0052 PF01933.13 CCC71251.1 - 1.4e-70 238.0 0.0 2.3e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 PLA2_B PF01735.13 CCC71252.1 - 1.2e-80 271.0 17.9 2.6e-64 217.1 5.1 3.0 2 1 0 2 2 2 2 Lysophospholipase catalytic domain Inhibitor_I9 PF05922.11 CCC71253.1 - 4.7e-07 30.2 0.2 5.8e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I9 PurS PF02700.9 CCC71253.1 - 0.039 13.9 0.2 0.052 13.5 0.1 1.3 1 1 0 1 1 1 0 Phosphoribosylformylglycinamidine (FGAM) synthase Frataxin_Cyay PF01491.11 CCC71254.1 - 3.6e-28 97.5 0.0 4.7e-28 97.1 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain UCH PF00443.24 CCC71255.1 - 8.2e-43 146.4 6.6 1.1e-42 145.9 4.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC71255.1 - 4.1e-13 49.4 11.2 7.3e-12 45.3 7.7 2.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Y_phosphatase2 PF03162.8 CCC71256.1 - 9.5e-65 216.9 0.0 1.6e-64 216.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 CCC71256.1 - 1.7e-07 31.6 0.0 6.3e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 CCC71256.1 - 0.005 16.4 0.0 0.0091 15.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 CCC71256.1 - 0.0051 16.1 0.0 0.009 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Glyco_transf_25 PF01755.12 CCC71256.1 - 0.082 12.5 0.7 0.16 11.6 0.5 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) Histone PF00125.19 CCC71257.1 - 5.2e-30 103.3 0.7 8.5e-30 102.7 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCC71257.1 - 9.4e-07 28.9 0.0 1.4e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 CCC71257.1 - 0.002 18.1 1.0 0.0025 17.8 0.1 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 CCC71257.1 - 0.058 13.1 0.1 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.19 CCC71258.1 - 2.5e-15 56.3 0.2 3.1e-15 56.0 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 CCC71258.1 - 3.2e-05 23.8 0.1 5.6e-05 23.1 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAF PF02969.12 CCC71258.1 - 4.4e-05 23.3 0.2 6.2e-05 22.8 0.1 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 CCC71258.1 - 5e-05 23.3 0.1 7e-05 22.9 0.1 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 CCC71258.1 - 0.0012 18.1 0.0 0.0013 18.0 0.0 1.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 CCC71258.1 - 0.0042 16.7 0.0 0.0052 16.4 0.0 1.3 1 1 0 1 1 1 1 Bromodomain associated TFIID_20kDa PF03847.8 CCC71258.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.10 CCC71258.1 - 0.14 11.9 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Glyco_transf_15 PF01793.11 CCC71259.1 - 4e-121 403.9 14.6 1e-120 402.6 10.1 1.6 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase zf-H2C2_2 PF13465.1 CCC71260.1 - 4.9e-14 51.8 10.7 7.5e-09 35.4 0.3 4.1 3 1 0 3 3 3 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC71260.1 - 2.4e-11 43.1 10.1 6.8e-05 22.9 0.7 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 CCC71260.1 - 1.8e-09 37.3 28.0 4.7e-07 29.7 0.8 4.3 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCC71260.1 - 4.3e-07 29.9 7.6 0.00023 21.2 0.2 3.5 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 CCC71260.1 - 5.8e-07 29.5 5.5 1.5e-05 24.9 0.2 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type Zn_ribbon_recom PF13408.1 CCC71260.1 - 0.022 14.9 4.7 0.022 14.9 3.3 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain C1_4 PF07975.7 CCC71260.1 - 1.5 8.8 4.3 18 5.4 2.2 2.8 2 1 1 3 3 3 0 TFIIH C1-like domain Met_10 PF02475.11 CCC71261.1 - 1.7e-09 37.5 0.0 3.2e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 CCC71261.1 - 0.00018 21.1 0.1 0.00037 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 CCC71261.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain tRNA_U5-meth_tr PF05958.6 CCC71261.1 - 0.014 14.1 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_26 PF13659.1 CCC71261.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 CCC71261.1 - 0.029 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Bac_surface_Ag PF01103.18 CCC71262.1 - 1.8e-38 132.8 5.8 2.7e-38 132.2 4.0 1.3 1 0 0 1 1 1 1 Surface antigen DUF1242 PF06842.7 CCC71263.1 - 3.6e-18 64.7 0.4 4.7e-18 64.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Methyltransf_16 PF10294.4 CCC71264.1 - 4.2e-50 169.5 0.0 6.7e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 CCC71264.1 - 0.0048 16.2 0.0 0.0078 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CCC71264.1 - 0.053 14.0 0.0 0.11 13.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF1413 PF07205.6 CCC71264.1 - 0.074 12.5 1.0 0.13 11.8 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) R3H PF01424.17 CCC71265.1 - 5.7e-10 38.7 0.0 1.3e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 CCC71265.1 - 9e-08 31.9 58.3 2.7e-05 23.9 13.2 12.5 12 2 0 12 12 12 5 NF-X1 type zinc finger Nol1_Nop2_Fmu PF01189.12 CCC71266.1 - 1.8e-17 63.6 0.0 6.5e-12 45.4 0.0 2.2 2 0 0 2 2 2 2 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 CCC71266.1 - 0.00081 19.4 0.0 0.0024 17.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Hist_deacetyl PF00850.14 CCC71267.1 - 6.6e-96 321.2 0.0 8.8e-96 320.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 CCC71267.1 - 1.1e-53 181.3 0.6 1.7e-53 180.7 0.4 1.3 1 0 0 1 1 1 1 Arb2 domain Pkinase PF00069.20 CCC71268.1 - 2.8e-38 131.5 0.0 6.4e-38 130.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71268.1 - 2.9e-30 105.1 0.0 6.8e-30 104.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC71268.1 - 1.8e-06 27.1 0.4 1.6e-05 24.0 0.0 2.3 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCC71268.1 - 0.007 16.1 0.0 0.071 12.8 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Epimerase PF01370.16 CCC71269.1 - 4.9e-16 58.8 0.0 6.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCC71269.1 - 2e-11 43.1 0.0 2.8e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCC71269.1 - 2.5e-09 36.4 0.0 1.1e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CCC71269.1 - 2.3e-08 34.2 0.2 5.6e-08 32.9 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 CCC71269.1 - 2.1e-06 27.1 0.1 0.0028 16.9 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family adh_short PF00106.20 CCC71269.1 - 1.6e-05 24.9 0.4 3e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCC71269.1 - 6e-05 22.0 0.2 8.6e-05 21.5 0.1 1.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 CCC71269.1 - 0.0045 16.6 0.0 0.011 15.3 0.0 1.6 2 0 0 2 2 2 1 KR domain ELFV_dehydrog PF00208.16 CCC71269.1 - 0.016 14.8 0.5 0.06 12.9 0.1 1.9 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DapB_N PF01113.15 CCC71269.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_16 PF10294.4 CCC71272.1 - 4.2e-50 169.5 0.0 6.7e-50 168.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 CCC71272.1 - 0.0048 16.2 0.0 0.0078 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 CCC71272.1 - 0.053 14.0 0.0 0.11 13.1 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain DUF1413 PF07205.6 CCC71272.1 - 0.074 12.5 1.0 0.13 11.8 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1413) Bac_surface_Ag PF01103.18 CCC71273.1 - 1.8e-38 132.8 5.8 2.7e-38 132.2 4.0 1.3 1 0 0 1 1 1 1 Surface antigen WD40 PF00400.27 CCC71274.1 - 1.1e-11 44.1 0.9 9.4e-07 28.4 0.2 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat Myb_DNA-binding PF00249.26 CCC71275.1 - 3.6e-06 26.9 0.0 1.3e-05 25.1 0.0 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Complex1_LYR_1 PF13232.1 CCC71275.1 - 0.088 13.0 6.0 0.062 13.5 1.6 2.5 2 0 0 2 2 2 0 Complex1_LYR-like PIG-H PF10181.4 CCC71276.1 - 7.2e-19 67.1 0.7 5.2e-18 64.4 0.1 2.1 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component Glyco_hydro_15 PF00723.16 CCC71277.1 - 4.6e-52 177.0 0.0 5.6e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Pro_CA PF00484.14 CCC71278.1 - 4.5e-35 120.9 0.0 5.9e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase COG6 PF06419.6 CCC71280.1 - 7e-147 490.2 38.8 7e-147 490.2 26.9 1.6 2 1 0 2 2 2 1 Conserved oligomeric complex COG6 RTBV_P12 PF06361.6 CCC71280.1 - 0.013 15.7 5.0 3.5 7.8 0.1 3.7 4 0 0 4 4 4 0 Rice tungro bacilliform virus P12 protein DUF1269 PF06897.7 CCC71280.1 - 0.16 12.0 1.2 2.7 8.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1269) DUF2722 PF10846.3 CCC71281.1 - 4.5e-44 151.1 29.4 1e-43 149.9 20.4 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2722) zf-Nse PF11789.3 CCC71282.1 - 2.3e-21 75.0 0.2 5.5e-21 73.8 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_2 PF13639.1 CCC71282.1 - 4.8e-05 23.0 1.7 0.00016 21.4 0.9 2.1 2 0 0 2 2 2 1 Ring finger domain Rtf2 PF04641.7 CCC71282.1 - 0.00026 20.3 0.1 0.00026 20.3 0.1 1.7 2 0 0 2 2 2 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 CCC71282.1 - 0.0006 19.4 0.2 0.0015 18.1 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCC71282.1 - 0.00078 19.1 0.7 0.0022 17.6 0.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 CCC71282.1 - 0.002 18.0 1.7 0.0063 16.5 1.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 CCC71282.1 - 0.023 14.5 0.1 0.039 13.7 0.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 CCC71282.1 - 0.042 13.3 0.2 0.1 12.1 0.1 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 CCC71282.1 - 0.084 12.9 0.0 0.27 11.3 0.0 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_5 PF14634.1 CCC71282.1 - 0.5 10.1 4.8 0.098 12.4 0.8 1.9 2 0 0 2 2 2 0 zinc-RING finger domain TPP_enzyme_N PF02776.13 CCC71283.1 - 7.9e-42 142.6 0.0 1.2e-41 142.0 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 CCC71283.1 - 1.1e-21 77.0 0.0 1.9e-21 76.2 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 CCC71283.1 - 2.2e-20 72.7 0.2 8.3e-20 70.9 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MFS_1 PF07690.11 CCC71284.1 - 9.6e-29 100.1 4.5 9.6e-29 100.1 3.1 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCC71284.1 - 5.4e-11 41.7 2.2 5.4e-11 41.7 1.5 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 CCC71284.1 - 3.8e-05 22.2 1.5 3.8e-05 22.2 1.1 2.5 2 1 0 2 2 2 1 MFS/sugar transport protein TRI12 PF06609.8 CCC71284.1 - 0.0031 15.7 0.3 0.0031 15.7 0.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-Tim10_DDP PF02953.10 CCC71285.1 - 8.9e-21 72.9 5.8 1.2e-20 72.5 4.0 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Ku_PK_bind PF08785.6 CCC71285.1 - 0.02 14.7 2.1 0.023 14.6 1.5 1.1 1 0 0 1 1 1 0 Ku C terminal domain like Mmp37 PF09139.6 CCC71285.1 - 0.058 12.4 0.3 0.062 12.3 0.2 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 Phasin_2 PF09361.5 CCC71285.1 - 0.096 12.7 0.1 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 Phasin protein Pepsin-I3 PF06394.8 CCC71285.1 - 0.11 12.1 0.6 0.66 9.6 0.0 2.0 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain Vicilin_N PF04702.7 CCC71285.1 - 0.78 9.3 4.9 1 8.9 3.4 1.2 1 0 0 1 1 1 0 Vicilin N terminal region OMPdecase PF00215.19 CCC71286.1 - 7.6e-77 257.7 0.0 8.7e-77 257.5 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Sec7 PF01369.15 CCC71287.1 - 6.7e-63 211.8 0.6 2e-62 210.2 0.1 2.1 1 1 1 2 2 2 1 Sec7 domain DUF2235 PF09994.4 CCC71288.1 - 6.5e-79 265.1 0.0 8.4e-79 264.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) UCR_TM PF02921.9 CCC71289.1 - 3.5e-20 71.9 1.4 5.9e-20 71.2 1.0 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 CCC71289.1 - 2.1e-17 62.4 0.0 3.4e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Nucleopor_Nup85 PF07575.8 CCC71290.1 - 9.2e-164 545.7 5.0 1.1e-163 545.5 3.4 1.0 1 0 0 1 1 1 1 Nup85 Nucleoporin PfkB PF00294.19 CCC71291.1 - 4.8e-09 35.7 0.0 1.3e-07 31.0 0.0 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CCC71291.1 - 4.3e-08 32.6 0.0 5.1e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Aminotran_1_2 PF00155.16 CCC71292.1 - 1.6e-43 149.0 0.0 2.8e-43 148.2 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 CCC71292.1 - 2.3e-08 33.5 0.0 3.3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 CCC71292.1 - 4.3e-08 32.3 0.0 6.4e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 CCC71292.1 - 8.7e-07 27.5 0.0 1.2e-06 27.0 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 CCC71292.1 - 0.00027 20.0 0.0 0.0004 19.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 CCC71292.1 - 0.023 13.1 0.0 0.071 11.5 0.0 1.7 2 0 0 2 2 2 0 Pyridoxal-dependent decarboxylase conserved domain Aminotran_MocR PF12897.2 CCC71292.1 - 0.081 11.4 0.0 0.17 10.3 0.0 1.6 1 1 0 1 1 1 0 Alanine-glyoxylate amino-transferase MCM PF00493.18 CCC71294.1 - 2.6e-129 430.8 0.2 3.5e-129 430.3 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 CCC71294.1 - 1.8e-22 80.0 0.1 7.5e-22 78.0 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 CCC71294.1 - 1.5e-07 30.8 0.0 1.6e-06 27.4 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ORC6 PF05460.8 CCC71294.1 - 5.3e-05 22.4 5.8 0.0001 21.5 4.0 1.4 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) AAA_3 PF07726.6 CCC71294.1 - 0.0056 16.2 0.0 0.014 15.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 CCC71294.1 - 0.013 14.9 0.0 0.036 13.5 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain PBP1_TM PF14812.1 CCC71294.1 - 5.8 7.2 20.2 2.2 8.6 1.3 4.6 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3589 PF12141.3 CCC71295.1 - 4.6e-102 341.8 0.5 1.5e-101 340.0 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) eIF-5a PF01287.15 CCC71296.1 - 8.7e-27 92.8 0.3 1.3e-26 92.3 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 CCC71296.1 - 0.00035 20.1 0.7 0.00073 19.1 0.5 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 CCC71296.1 - 0.0013 18.5 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain IgaA PF07095.6 CCC71297.1 - 0.058 11.1 0.0 0.069 10.9 0.0 1.0 1 0 0 1 1 1 0 Intracellular growth attenuator protein IgaA Anp1 PF03452.9 CCC71298.1 - 2.6e-122 407.1 0.0 3.6e-122 406.7 0.0 1.1 1 0 0 1 1 1 1 Anp1 UBA PF00627.26 CCC71299.1 - 1.3e-22 78.9 2.6 2.5e-13 49.4 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 CCC71299.1 - 9.6e-17 60.1 0.7 5.8e-16 57.6 0.6 2.0 2 0 0 2 2 2 1 Ubiquitin family XPC-binding PF09280.6 CCC71299.1 - 5e-12 45.1 0.6 9.4e-12 44.2 0.4 1.4 1 0 0 1 1 1 1 XPC-binding domain Rad60-SLD PF11976.3 CCC71299.1 - 2.7e-09 36.5 0.9 6e-09 35.4 0.6 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 CCC71299.1 - 2.8e-06 27.1 0.2 5.6e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF1421 PF07223.6 CCC71299.1 - 5.7e-05 23.0 3.7 5.7e-05 23.0 2.6 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1421) DUF2407 PF10302.4 CCC71299.1 - 0.002 18.3 0.0 0.0036 17.4 0.0 1.5 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain CUE PF02845.11 CCC71299.1 - 0.0098 15.3 0.7 1.4 8.5 0.0 4.3 3 2 1 4 4 4 1 CUE domain YukD PF08817.5 CCC71299.1 - 0.025 15.1 0.0 0.065 13.7 0.0 1.8 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD UBA_3 PF09288.5 CCC71299.1 - 0.067 12.7 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Mitofilin PF09731.4 CCC71299.1 - 0.31 9.6 8.9 0.41 9.2 6.2 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DLIC PF05783.6 CCC71299.1 - 0.43 9.2 2.9 0.67 8.5 2.0 1.3 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) PRCC PF10253.4 CCC71299.1 - 2.8 8.6 10.7 1.6 9.4 3.7 2.3 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Mucin PF01456.12 CCC71299.1 - 3.3 7.4 32.5 2.1 8.1 14.7 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein HAD_2 PF13419.1 CCC71300.1 - 4.2e-19 69.4 0.0 5.4e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase SLD3 PF08639.5 CCC71300.1 - 0.068 11.8 0.0 0.092 11.3 0.0 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 Cytochrom_C PF00034.16 CCC71301.1 - 4.8e-10 40.1 0.0 7.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 CCC71301.1 - 1.6e-07 31.3 1.8 2e-06 27.8 1.3 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 CCC71301.1 - 0.019 14.4 0.4 0.12 11.7 0.1 2.0 2 0 0 2 2 2 0 Cytochrome c-550 domain Haem_bd PF14376.1 CCC71301.1 - 0.11 12.1 0.5 0.34 10.6 0.0 1.9 2 1 0 2 2 2 0 Haem-binding domain Glyco_hydro_16 PF00722.16 CCC71302.1 - 2.5e-43 147.4 5.5 2.5e-43 147.4 3.8 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Methylase_S PF01420.14 CCC71302.1 - 0.021 14.8 0.9 0.072 13.0 0.2 2.1 2 0 0 2 2 2 0 Type I restriction modification DNA specificity domain NPR3 PF03666.8 CCC71302.1 - 0.4 9.1 3.7 0.61 8.5 2.6 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Chitin_bind_1 PF00187.14 CCC71302.1 - 0.68 9.9 14.7 1.3 9.0 10.2 1.4 1 0 0 1 1 1 0 Chitin recognition protein KAR9 PF08580.5 CCC71302.1 - 0.75 7.9 14.4 1.1 7.4 10.0 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Menin PF05053.8 CCC71302.1 - 1.5 6.8 7.3 2.1 6.4 5.1 1.1 1 0 0 1 1 1 0 Menin DUF515 PF04415.7 CCC71302.1 - 8.6 4.4 28.9 12 3.9 20.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) DUF566 PF04484.7 CCC71302.1 - 9 5.6 17.3 13 5.1 12.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) NAD_kinase PF01513.16 CCC71303.1 - 2.8e-79 265.8 0.0 4.6e-79 265.1 0.0 1.3 1 0 0 1 1 1 1 ATP-NAD kinase GDA1_CD39 PF01150.12 CCC71304.1 - 8.5e-117 390.2 0.0 1.1e-116 389.9 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family YL1_C PF08265.6 CCC71306.1 - 6.5e-15 54.3 0.3 1.2e-14 53.5 0.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain FAD_binding_2 PF00890.19 CCC71307.1 - 1.1e-73 248.4 0.0 1.3e-73 248.2 0.0 1.0 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 CCC71307.1 - 4.7e-08 32.3 1.1 0.00024 20.1 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCC71307.1 - 1.5e-07 31.7 0.0 9e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 CCC71307.1 - 1.5e-06 28.2 1.9 8.7e-05 22.4 0.4 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 CCC71307.1 - 4.4e-06 25.9 1.0 0.0028 16.7 0.0 2.4 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 CCC71307.1 - 2.5e-05 24.1 0.1 0.00029 20.7 0.1 2.5 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 CCC71307.1 - 0.00035 20.3 0.1 0.0022 17.7 0.0 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 CCC71307.1 - 0.0096 15.0 0.1 0.12 11.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain GMC_oxred_N PF00732.14 CCC71307.1 - 0.024 13.8 1.0 0.35 9.9 0.0 2.6 3 0 0 3 3 3 0 GMC oxidoreductase FAD_oxidored PF12831.2 CCC71307.1 - 0.026 13.6 0.4 0.15 11.1 0.3 1.9 1 1 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 CCC71307.1 - 0.027 13.4 0.1 0.06 12.2 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 CCC71307.1 - 0.071 11.5 5.1 1.4 7.3 0.3 2.9 3 0 0 3 3 3 0 HI0933-like protein UPF0300 PF08594.5 CCC71307.1 - 0.087 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) DnaA_N PF11638.3 CCC71307.1 - 0.1 12.1 0.2 17 5.0 0.0 3.0 2 1 0 2 2 2 0 DnaA N-terminal domain Sedlin_N PF04628.8 CCC71308.1 - 1.3e-08 34.7 0.5 1.6e-08 34.5 0.3 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Ribosomal_L27 PF01016.14 CCC71311.1 - 3.8e-30 103.5 0.0 6.5e-30 102.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L27 protein Dimer_Tnp_hAT PF05699.9 CCC71312.1 - 3e-06 26.7 0.1 1e-05 25.0 0.1 1.9 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-BED PF02892.10 CCC71314.1 - 0.013 15.2 0.6 0.03 14.0 0.4 1.7 1 0 0 1 1 1 0 BED zinc finger RRM_1 PF00076.17 CCC71315.1 - 8.8e-63 207.8 0.0 8.5e-21 73.3 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC71315.1 - 4.1e-41 138.8 0.0 2.3e-13 49.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC71315.1 - 9.2e-16 57.4 0.0 1e-06 28.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCC71315.1 - 0.0073 16.0 0.0 3.6 7.4 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Mito_carr PF00153.22 CCC71316.1 - 2.2e-46 155.5 1.4 2.9e-15 55.7 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein Axin_b-cat_bind PF08833.5 CCC71316.1 - 0.11 12.1 0.5 0.21 11.3 0.4 1.4 1 0 0 1 1 1 0 Axin beta-catenin binding domain PUL PF08324.6 CCC71317.1 - 5.4e-56 189.3 6.1 8.3e-56 188.7 4.2 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.6 CCC71317.1 - 5.5e-44 148.8 0.2 1.8e-43 147.2 0.1 2.0 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 CCC71317.1 - 1.4e-38 129.3 20.0 8.8e-09 34.9 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 CCC71317.1 - 0.00025 20.7 3.1 1.2 8.9 0.0 4.0 2 1 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region VCBS PF13517.1 CCC71317.1 - 0.76 10.1 3.8 3 8.2 0.0 3.8 6 0 0 6 6 6 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella RRM_6 PF14259.1 CCC71318.1 - 0.00016 21.5 0.0 0.00029 20.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCC71318.1 - 0.0006 19.3 0.1 0.00099 18.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 CCC71318.1 - 0.004 17.5 13.1 0.039 14.4 9.1 2.2 1 1 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_5 PF13893.1 CCC71318.1 - 0.006 16.4 0.0 0.0095 15.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sir1 PF11603.3 CCC71320.1 - 6.7e-05 23.0 0.0 0.00013 22.0 0.0 1.4 1 0 0 1 1 1 1 Regulatory protein Sir1 DEAD PF00270.24 CCC71320.1 - 0.006 16.0 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF276 PF03434.8 CCC71322.1 - 0.002 17.1 0.2 0.0034 16.3 0.1 1.3 1 0 0 1 1 1 1 DUF276 Topo-VIb_trans PF09239.6 CCC71323.1 - 0.07 12.6 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Topoisomerase VI B subunit, transducer DUF4659 PF15558.1 CCC71324.1 - 0.021 13.4 2.4 0.028 13.0 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4659) Hexapep PF00132.19 CCC71325.1 - 3.2e-15 54.8 16.7 1e-10 40.6 3.7 3.5 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 CCC71325.1 - 6.2e-13 48.0 15.2 3.5e-09 36.0 1.7 2.7 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase DUF2602 PF10782.4 CCC71325.1 - 0.024 14.4 0.0 0.045 13.6 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2602) FAD-oxidase_C PF02913.14 CCC71326.1 - 3.1e-49 167.5 0.0 4.4e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 CCC71326.1 - 3.3e-35 120.5 0.0 5.9e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NBP1 PF08537.5 CCC71327.1 - 1e-39 136.6 33.8 2.2e-37 129.0 23.5 2.0 1 1 0 1 1 1 1 Fungal Nap binding protein NBP1 Pyridox_oxidase PF01243.15 CCC71328.1 - 1.6e-16 60.0 0.0 4.1e-15 55.5 0.0 2.6 2 1 1 3 3 3 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 CCC71328.1 - 4.6e-05 23.2 0.0 0.0016 18.2 0.0 2.1 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase AvrB_AvrC PF05394.6 CCC71328.1 - 0.02 13.8 0.2 0.026 13.4 0.1 1.1 1 0 0 1 1 1 0 Avirulence protein Pga1 PF10333.4 CCC71328.1 - 0.032 13.9 0.7 0.3 10.7 0.0 2.2 1 1 1 2 2 2 0 GPI-Mannosyltransferase II co-activator SpoU_methylase PF00588.14 CCC71328.1 - 0.1 12.4 0.1 4.6 7.1 0.0 2.1 2 0 0 2 2 2 0 SpoU rRNA Methylase family PWWP PF00855.12 CCC71329.1 - 4e-18 65.3 0.2 1e-17 64.0 0.1 1.7 1 0 0 1 1 1 1 PWWP domain DUF998 PF06197.8 CCC71330.1 - 0.063 12.5 0.6 0.078 12.2 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF4131 PF13567.1 CCC71330.1 - 0.085 12.2 0.2 0.1 12.0 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3810 PF12725.2 CCC71330.1 - 0.12 11.2 0.3 0.13 11.0 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Med10 PF09748.4 CCC71331.1 - 9.7e-45 151.5 0.2 1.2e-44 151.2 0.1 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PBS_linker_poly PF00427.16 CCC71331.1 - 0.051 13.2 0.0 0.08 12.6 0.0 1.4 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide Ras PF00071.17 CCC71332.1 - 3.8e-55 185.6 0.0 5e-55 185.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC71332.1 - 6.1e-16 58.9 0.0 9.4e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 CCC71332.1 - 8.3e-07 28.4 0.0 1.3e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 CCC71332.1 - 0.0092 15.1 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCC71332.1 - 0.062 12.5 0.0 0.089 12.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Fmp27 PF10344.4 CCC71333.1 - 1e-125 420.5 51.2 1.9e-125 419.6 35.5 1.4 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Fmp27_WPPW PF10359.4 CCC71333.1 - 8.4e-116 387.1 8.3 1.7e-115 386.2 5.7 1.5 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Apt1 PF10351.4 CCC71333.1 - 3.5e-89 299.7 14.0 6.3e-62 209.9 4.1 2.7 1 1 1 2 2 2 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.4 CCC71333.1 - 1.4e-54 184.2 0.2 4.1e-54 182.7 0.2 1.9 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 CCC71333.1 - 1.7e-48 164.3 2.0 1.7e-48 164.3 1.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 CCC71333.1 - 2.1e-31 108.3 0.5 4.2e-30 104.2 0.0 3.3 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain RRM_6 PF14259.1 CCC71334.1 - 2.2e-08 33.9 0.0 4.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCC71334.1 - 1.5e-05 24.5 0.0 3.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2559 PF10832.3 CCC71334.1 - 0.00074 19.2 12.7 2.7 7.8 0.0 5.8 5 1 1 6 6 6 3 Protein of unknown function (DUF2559) RRM_5 PF13893.1 CCC71334.1 - 0.042 13.6 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RGS PF00615.14 CCC71336.1 - 5e-17 62.1 1.2 5e-12 45.9 0.1 2.6 2 0 0 2 2 2 2 Regulator of G protein signaling domain DEP PF00610.16 CCC71336.1 - 4.7e-09 35.8 0.0 6.3e-08 32.2 0.0 2.4 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) LRRC37AB_C PF14914.1 CCC71336.1 - 0.0021 17.5 0.7 0.006 16.0 0.1 2.0 2 1 0 2 2 2 1 LRRC37A/B like protein 1 C-terminal domain Zn_clus PF00172.13 CCC71337.1 - 2e-08 34.0 10.4 4.1e-08 32.9 7.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 CCC71338.1 - 1.9e-26 92.6 34.6 6.3e-19 67.8 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 CCC71338.1 - 6e-10 38.1 18.0 8.1e-08 31.0 0.6 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.3 CCC71338.1 - 4.5e-06 25.4 5.7 4.5e-06 25.4 3.9 3.0 3 0 0 3 3 3 2 Vacuole effluxer Atg22 like OATP PF03137.15 CCC71338.1 - 0.0013 16.8 0.8 0.0013 16.8 0.6 2.6 3 1 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 CCC71338.1 - 0.0031 16.1 19.6 0.018 13.6 13.4 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 CCC71338.1 - 0.018 14.8 0.4 0.018 14.8 0.3 3.6 5 0 0 5 5 5 0 MFS_1 like family Ribosomal_S7 PF00177.16 CCC71339.1 - 2.9e-39 133.9 1.7 3.9e-39 133.5 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e GCV_T PF01571.16 CCC71340.1 - 2.5e-09 36.8 0.0 0.00088 18.7 0.0 3.2 3 0 0 3 3 3 3 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 CCC71340.1 - 0.032 14.2 0.0 0.084 12.9 0.0 1.7 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain ATP-synt_ab PF00006.20 CCC71341.1 - 5.1e-63 212.4 0.0 8e-63 211.8 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCC71341.1 - 2.7e-26 92.2 0.2 4.9e-26 91.4 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCC71341.1 - 4.4e-23 81.2 1.8 1.1e-22 79.9 1.3 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain KaiC PF06745.8 CCC71341.1 - 0.00029 20.0 0.1 0.00051 19.2 0.1 1.4 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.1 CCC71341.1 - 0.0063 15.9 0.1 0.02 14.2 0.1 1.9 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 CCC71341.1 - 0.0078 15.9 0.2 0.54 9.9 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 CCC71341.1 - 0.018 15.2 0.2 0.35 11.0 0.0 2.9 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 CCC71341.1 - 0.022 14.3 0.2 0.076 12.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.17 CCC71341.1 - 0.029 13.2 0.7 0.52 9.1 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain DUF258 PF03193.11 CCC71341.1 - 0.04 13.0 0.1 0.074 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 CCC71341.1 - 0.046 13.7 0.6 0.24 11.3 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 CCC71341.1 - 0.053 13.2 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 CCC71341.1 - 0.071 13.2 0.0 0.18 11.9 0.0 1.7 2 0 0 2 2 1 0 RNA helicase JmjC PF02373.17 CCC71342.1 - 3.9e-36 123.7 1.6 9.2e-36 122.5 1.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 CCC71342.1 - 9.5e-10 37.8 0.0 3.6e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 jmjN domain PHD PF00628.24 CCC71342.1 - 0.0004 20.0 8.8 0.0004 20.0 6.1 2.5 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.17 CCC71342.1 - 0.012 15.3 7.4 0.012 15.3 5.2 2.8 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-HC5HC2H PF13771.1 CCC71342.1 - 0.03 14.4 6.4 0.15 12.2 3.0 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain Zn_ribbon_recom PF13408.1 CCC71342.1 - 0.091 13.0 8.1 0.051 13.8 2.0 2.6 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Mating_N PF12731.2 CCC71342.1 - 0.1 12.4 0.2 5.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Mating-type protein beta 1 Lar_restr_allev PF14354.1 CCC71342.1 - 0.11 12.8 0.2 0.11 12.8 0.1 2.8 2 1 0 2 2 1 0 Restriction alleviation protein Lar PHD_2 PF13831.1 CCC71342.1 - 0.52 9.6 8.2 1.8 7.9 3.4 2.7 2 0 0 2 2 2 0 PHD-finger CENP-B_dimeris PF09026.5 CCC71342.1 - 0.6 10.3 3.5 13 6.0 0.1 2.7 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zf-RING_2 PF13639.1 CCC71342.1 - 2.8 7.8 8.9 13 5.7 5.0 2.8 2 0 0 2 2 2 0 Ring finger domain Ilm1 PF10311.4 CCC71343.1 - 6.5e-42 142.8 12.0 8.5e-42 142.4 8.3 1.1 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 COX2_TM PF02790.10 CCC71343.1 - 1.1 9.2 6.6 0.22 11.4 1.0 2.3 2 1 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain Rpn3_C PF08375.6 CCC71344.1 - 3.9e-19 68.8 2.0 7.9e-19 67.8 1.4 1.5 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 CCC71344.1 - 4.8e-19 68.6 0.4 1.8e-18 66.7 0.3 2.1 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 CCC71344.1 - 0.0043 16.8 0.1 0.011 15.4 0.1 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Peptidase_M48 PF01435.13 CCC71345.1 - 1.1e-45 156.0 0.0 1.5e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 CCC71345.1 - 0.0017 17.3 1.1 0.0029 16.6 0.8 1.3 1 0 0 1 1 1 1 BlaR1 peptidase M56 DUF2268 PF10026.4 CCC71345.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) TRAM_LAG1_CLN8 PF03798.11 CCC71346.1 - 4e-29 101.5 18.1 4e-29 101.5 12.6 1.5 2 0 0 2 2 2 1 TLC domain PfkB PF00294.19 CCC71347.1 - 1.5e-72 244.3 2.4 1.8e-72 244.0 1.6 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 CCC71347.1 - 6.2e-06 25.5 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Na_Ca_ex PF01699.19 CCC71348.1 - 1.7e-51 173.4 24.9 1.2e-31 109.1 5.7 2.7 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF1510 PF07423.6 CCC71348.1 - 1.5 8.1 5.7 0.15 11.3 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Lipase_3 PF01764.20 CCC71349.1 - 1.6e-35 121.8 0.0 3e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF1743 PF08489.6 CCC71349.1 - 0.0039 16.9 0.1 0.0092 15.7 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF1743) Cutinase PF01083.17 CCC71349.1 - 0.046 13.4 0.0 0.083 12.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase DUF2974 PF11187.3 CCC71349.1 - 0.061 12.6 0.1 0.42 9.9 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2974) CPSase_L_D2 PF02786.12 CCC71351.1 - 2.3e-110 366.8 0.0 5.2e-84 280.7 0.0 2.4 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 CCC71351.1 - 7.5e-38 129.0 0.1 1.5e-37 128.0 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 CCC71351.1 - 1.1e-35 122.0 0.0 5.1e-17 61.9 0.0 2.6 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 CCC71351.1 - 1.2e-35 122.9 0.0 4e-20 72.3 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 CCC71351.1 - 7e-22 77.5 0.0 1.3e-08 33.9 0.0 3.7 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 CCC71351.1 - 2.6e-18 65.9 0.0 5.2e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCC71351.1 - 6.9e-14 51.7 0.2 5e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 CCC71351.1 - 1.5e-09 37.5 0.1 0.00021 20.8 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain MGS PF02142.17 CCC71351.1 - 2.4e-06 27.3 0.0 8.9e-06 25.5 0.0 2.0 2 0 0 2 2 1 1 MGS-like domain ATP-grasp_3 PF02655.9 CCC71351.1 - 6.8e-06 26.0 0.1 0.04 13.7 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_5 PF13549.1 CCC71351.1 - 0.0058 15.8 0.0 0.12 11.5 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain Epimerase PF01370.16 CCC71351.1 - 0.01 15.2 0.0 0.86 8.9 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Yippee-Mis18 PF03226.9 CCC71352.1 - 1.8e-17 63.1 0.6 2.4e-17 62.7 0.4 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Myotub-related PF06602.9 CCC71353.1 - 1.8e-124 415.0 0.3 2.4e-124 414.7 0.2 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 CCC71353.1 - 0.0029 16.9 0.0 0.0062 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase GRAM PF02893.15 CCC71353.1 - 0.031 13.8 0.0 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 GRAM domain Y_phosphatase3 PF13350.1 CCC71353.1 - 0.037 14.2 0.0 0.089 13.0 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 CCC71353.1 - 0.051 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CMD PF02627.15 CCC71354.1 - 3.6e-05 23.5 0.0 9.9e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Nnf1 PF03980.9 CCC71355.1 - 6.5e-28 96.8 11.1 1.4e-27 95.7 7.7 1.6 1 0 0 1 1 1 1 Nnf1 GnsAB PF08178.6 CCC71355.1 - 0.13 11.9 2.0 3.3 7.4 0.0 2.8 2 1 1 3 3 3 0 GnsA/GnsB family DUF1759 PF03564.10 CCC71355.1 - 0.24 11.2 0.2 0.24 11.2 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) Elongin_A PF06881.6 CCC71355.1 - 0.62 10.4 5.6 0.39 11.1 1.3 2.5 1 1 1 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF342 PF03961.8 CCC71355.1 - 0.96 7.7 6.3 1.4 7.2 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) SlyX PF04102.7 CCC71355.1 - 1 9.7 7.0 3.4 8.0 0.2 3.4 2 1 1 3 3 3 0 SlyX IncA PF04156.9 CCC71355.1 - 1.6 8.2 11.9 2.3 7.7 8.1 1.6 1 1 0 1 1 1 0 IncA protein Ribosomal_S7 PF00177.16 CCC71356.1 - 1.4e-31 109.0 0.1 1.9e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e NDUF_B4 PF07225.7 CCC71356.1 - 0.00052 19.8 0.0 0.00088 19.0 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) rve PF00665.21 CCC71357.1 - 2.9e-16 59.6 0.2 1e-15 57.9 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.1 CCC71357.1 - 0.018 14.5 0.0 0.049 13.1 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Sod_Cu PF00080.15 CCC71359.1 - 6.6e-45 152.7 2.3 7.6e-45 152.5 1.6 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) ESCRT-II PF05871.7 CCC71360.1 - 2.4e-48 163.5 4.8 2.9e-48 163.3 3.3 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Sod_Fe_C PF02777.13 CCC71361.1 - 3.5e-07 30.0 0.2 0.0026 17.5 0.0 2.2 1 1 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Scramblase PF03803.10 CCC71362.1 - 4.5e-71 238.4 0.1 5.3e-71 238.2 0.1 1.0 1 0 0 1 1 1 1 Scramblase Peptidase_C12 PF01088.16 CCC71363.1 - 1.8e-50 171.0 0.0 2.2e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF3115 PF11312.3 CCC71363.1 - 0.016 14.0 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) LCAT PF02450.10 CCC71364.1 - 4.7e-08 32.4 0.1 1.2e-07 31.0 0.0 1.8 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CCC71364.1 - 4.4e-07 30.0 0.0 7.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 CCC71364.1 - 1.2e-06 28.2 0.0 2.7e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 CCC71364.1 - 1.9e-06 27.6 0.1 6.6e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 CCC71364.1 - 0.00023 20.9 0.0 0.00043 20.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 CCC71364.1 - 0.0011 18.3 0.0 0.0028 17.0 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Ser_hydrolase PF06821.8 CCC71364.1 - 0.0027 17.3 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase DUF2305 PF10230.4 CCC71364.1 - 0.058 12.7 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DnaJ PF00226.26 CCC71365.1 - 4e-18 64.9 0.4 6e-18 64.3 0.3 1.3 1 0 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 CCC71365.1 - 2.4e-17 62.1 0.4 3.5e-17 61.6 0.3 1.3 1 0 0 1 1 1 1 CSL zinc finger Aldo_ket_red PF00248.16 CCC71366.1 - 2.2e-48 164.5 0.1 2.7e-48 164.2 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Mito_carr PF00153.22 CCC71367.1 - 3.5e-74 244.6 1.5 1e-24 86.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L37ae PF01780.14 CCC71368.1 - 1.8e-38 130.2 10.5 2e-38 130.0 7.3 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Rep_fac-A_C PF08646.5 CCC71368.1 - 0.042 13.5 1.1 0.048 13.3 0.7 1.2 1 0 0 1 1 1 0 Replication factor-A C terminal domain DUF1364 PF07102.7 CCC71368.1 - 0.061 13.2 1.7 0.078 12.8 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1364) Lar_restr_allev PF14354.1 CCC71368.1 - 0.086 13.1 0.9 0.13 12.5 0.6 1.3 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-C4_ClpX PF06689.8 CCC71368.1 - 0.25 10.9 5.3 1.4 8.5 3.7 2.1 1 1 0 1 1 1 0 ClpX C4-type zinc finger Zn_Tnp_IS1595 PF12760.2 CCC71368.1 - 0.32 10.8 5.2 0.53 10.1 3.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain YyzF PF14116.1 CCC71368.1 - 0.44 10.5 0.2 0.44 10.5 0.1 1.8 2 0 0 2 2 2 0 YyzF-like protein Elf1 PF05129.8 CCC71368.1 - 0.87 9.3 4.1 2.2 8.0 2.9 1.7 1 1 0 1 1 1 0 Transcription elongation factor Elf1 like CarbpepA_inh PF02977.10 CCC71368.1 - 1.2 8.8 7.1 10 5.7 4.9 2.1 1 1 0 1 1 1 0 Carboxypeptidase A inhibitor Fip1 PF05182.8 CCC71370.1 - 1.7e-21 75.2 0.9 2.9e-21 74.4 0.6 1.4 1 0 0 1 1 1 1 Fip1 motif Anillin PF08174.6 CCC71371.1 - 3e-07 30.5 0.9 1.5e-06 28.3 0.1 2.6 2 0 0 2 2 2 1 Cell division protein anillin PH PF00169.24 CCC71371.1 - 1.2e-06 28.6 0.1 7.8e-06 26.0 0.0 2.5 1 1 0 1 1 1 1 PH domain DUF3399 PF11879.3 CCC71371.1 - 0.0045 17.2 0.1 0.029 14.5 0.1 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3399) PUF PF00806.14 CCC71372.1 - 4.6e-27 91.9 1.0 0.00017 20.9 0.0 6.4 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat RRM_5 PF13893.1 CCC71372.1 - 3.9e-09 36.2 0.0 1.3e-08 34.5 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCC71372.1 - 6.3e-06 25.7 0.0 1.8e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC71372.1 - 0.022 14.7 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) F-box-like PF12937.2 CCC71373.1 - 1.1e-06 28.2 1.4 3e-06 26.8 1.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCC71373.1 - 0.0006 19.3 1.8 0.0026 17.3 0.8 2.5 2 0 0 2 2 2 1 F-box domain BIR PF00653.16 CCC71374.1 - 1.6e-07 31.6 5.2 0.00069 19.9 0.6 2.6 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain Evr1_Alr PF04777.8 CCC71375.1 - 2.2e-25 88.3 1.0 3.5e-25 87.7 0.7 1.3 1 0 0 1 1 1 1 Erv1 / Alr family Herpes_UL69 PF05459.7 CCC71375.1 - 0.059 12.5 0.2 0.51 9.4 0.0 2.0 1 1 1 2 2 2 0 Herpesvirus transcriptional regulator family Toxin-deaminase PF14424.1 CCC71375.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases G-gamma PF00631.17 CCC71376.1 - 6.2e-25 86.7 0.1 8.1e-25 86.3 0.1 1.2 1 0 0 1 1 1 1 GGL domain DUF3750 PF12570.3 CCC71376.1 - 0.12 12.6 0.1 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3750) ENTH PF01417.15 CCC71377.1 - 2.3e-42 143.8 0.0 4.7e-42 142.7 0.0 1.6 1 0 0 1 1 1 1 ENTH domain Sel1 PF08238.7 CCC71378.1 - 5.5e-18 64.9 18.2 1.7e-05 25.2 0.8 9.0 10 0 0 10 10 10 4 Sel1 repeat TPR_11 PF13414.1 CCC71378.1 - 0.0086 15.7 0.9 0.0086 15.7 0.6 4.7 5 1 1 6 6 6 1 TPR repeat TPR_7 PF13176.1 CCC71378.1 - 0.019 14.7 5.1 0.39 10.6 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat MobA_MobL PF03389.10 CCC71378.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 MobA/MobL family TPR_16 PF13432.1 CCC71378.1 - 0.33 11.6 6.6 0.46 11.2 0.1 4.0 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 CCC71378.1 - 0.7 10.4 6.9 22 5.8 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.27 CCC71380.1 - 2e-43 144.7 19.7 4.2e-10 39.1 0.5 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat YmzC PF14157.1 CCC71380.1 - 0.031 14.0 0.1 6.8 6.6 0.0 3.5 4 0 0 4 4 4 0 YmzC-like protein GPS PF01825.16 CCC71380.1 - 0.26 11.4 4.1 0.7 10.0 0.2 2.7 2 0 0 2 2 2 0 Latrophilin/CL-1-like GPS domain PNP_UDP_1 PF01048.15 CCC71381.1 - 7.3e-43 146.2 0.0 8.8e-43 145.9 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily Cyclin_N PF00134.18 CCC71382.1 - 3.1e-42 143.1 1.0 9.4e-42 141.5 0.1 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 CCC71382.1 - 8.5e-26 90.2 0.0 2.2e-25 88.8 0.0 1.7 2 0 0 2 2 2 1 Cyclin, C-terminal domain DUF4498 PF14926.1 CCC71383.1 - 0.0006 19.0 0.5 0.012 14.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4498) DUF2216 PF10226.4 CCC71383.1 - 0.027 13.9 1.3 0.046 13.2 0.3 1.8 2 0 0 2 2 2 0 Uncharacterized conserved proteins (DUF2216) Spectrin PF00435.16 CCC71383.1 - 0.056 13.7 3.6 0.067 13.4 0.7 2.4 2 1 1 3 3 3 0 Spectrin repeat Rootletin PF15035.1 CCC71383.1 - 0.43 10.5 9.6 0.052 13.5 2.4 2.3 2 2 1 3 3 3 0 Ciliary rootlet component, centrosome cohesion DUF1640 PF07798.6 CCC71383.1 - 0.48 10.4 7.3 0.059 13.4 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) FlaC_arch PF05377.6 CCC71383.1 - 2.9 7.8 6.3 7.3 6.5 0.2 3.2 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF972 PF06156.8 CCC71383.1 - 7.3 6.9 9.7 0.88 9.9 0.7 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF972) Tubulin PF00091.20 CCC71384.1 - 5.5e-68 229.0 0.1 1.7e-67 227.4 0.0 1.7 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCC71384.1 - 2.8e-27 95.2 0.4 4.8e-27 94.4 0.3 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 CCC71384.1 - 3.8e-08 33.3 0.1 9e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Glyco_hydro_16 PF00722.16 CCC71385.1 - 9.9e-42 142.3 0.0 1.5e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 CCC71385.1 - 7 6.7 12.2 13 5.8 8.4 1.4 1 0 0 1 1 1 0 Chitin recognition protein Cellulase PF00150.13 CCC71386.1 - 7e-14 51.6 0.4 4.2e-13 49.1 0.0 2.0 1 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) SNF2_N PF00176.18 CCC71387.1 - 4.3e-60 203.0 0.0 9.7e-60 201.8 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCC71387.1 - 1.5e-11 44.0 0.0 4.7e-11 42.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 CCC71387.1 - 3.9e-06 26.4 3.8 7.8e-06 25.5 2.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCC71387.1 - 8.3e-05 22.3 4.1 0.00016 21.4 2.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCC71387.1 - 0.00036 20.5 1.4 0.00087 19.2 1.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCC71387.1 - 0.0023 17.5 2.6 0.0044 16.6 1.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCC71387.1 - 0.0045 16.6 5.4 0.0091 15.6 3.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCC71387.1 - 0.058 13.1 1.0 0.2 11.4 0.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Zn_clus PF00172.13 CCC71388.1 - 2.8e-09 36.7 8.6 4.5e-09 36.0 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 CCC71389.1 - 2.2e-19 69.8 0.0 3e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 CCC71389.1 - 1.1e-09 37.4 0.0 1.4e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 CCC71389.1 - 1.7e-08 33.7 0.2 7.6e-08 31.5 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 CCC71389.1 - 3.2e-08 33.7 0.0 9e-08 32.3 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 CCC71389.1 - 7.4e-08 32.4 0.1 3.4e-07 30.3 0.0 1.9 1 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 CCC71389.1 - 0.00015 20.7 0.2 0.00047 19.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 CCC71389.1 - 0.00093 18.8 0.1 0.0032 17.1 0.1 1.8 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 CCC71389.1 - 0.011 14.9 0.1 0.023 13.9 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 CCC71389.1 - 0.018 13.9 0.0 0.032 13.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Transferrin PF00405.12 CCC71389.1 - 0.039 12.8 0.1 3.3 6.4 0.0 2.1 1 1 0 2 2 2 0 Transferrin DUF3450 PF11932.3 CCC71390.1 - 0.023 13.9 6.1 0.045 13.0 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) WXG100 PF06013.7 CCC71390.1 - 0.15 12.0 3.0 10 6.2 0.1 2.6 2 0 0 2 2 2 0 Proteins of 100 residues with WXG APG6 PF04111.7 CCC71390.1 - 0.2 10.6 13.2 0.21 10.5 6.4 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF342 PF03961.8 CCC71390.1 - 1.2 7.4 9.4 1.9 6.8 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4337 PF14235.1 CCC71390.1 - 1.9 8.3 5.4 3.8 7.3 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) IncA PF04156.9 CCC71390.1 - 6.6 6.2 11.6 7 6.1 6.9 1.8 1 1 0 1 1 1 0 IncA protein DUF367 PF04034.8 CCC71391.1 - 1.8e-51 173.0 0.0 2.7e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 CCC71391.1 - 9.4e-14 50.7 0.2 1.5e-13 50.0 0.2 1.3 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI RHS_repeat PF05593.9 CCC71391.1 - 0.00022 21.2 0.0 0.044 13.9 0.0 2.6 2 0 0 2 2 2 2 RHS Repeat Spore_III_AB PF09548.5 CCC71391.1 - 0.05 13.3 1.7 0.09 12.5 0.5 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) Ank_5 PF13857.1 CCC71392.1 - 3.8e-06 26.9 0.0 0.00074 19.6 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) VPS9 PF02204.13 CCC71392.1 - 1.1e-05 25.3 1.0 1.1e-05 25.3 0.7 2.7 3 0 0 3 3 3 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 CCC71392.1 - 9e-05 22.7 0.0 0.058 13.7 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 CCC71392.1 - 0.0052 16.5 0.0 0.13 12.1 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat TPR_11 PF13414.1 CCC71393.1 - 1.1e-25 89.0 13.5 4.7e-17 61.3 2.4 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 CCC71393.1 - 2.4e-17 61.6 10.8 1.2e-07 31.0 0.6 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 CCC71393.1 - 2.6e-14 51.9 9.0 9.1e-05 22.0 0.4 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCC71393.1 - 3.5e-08 33.0 2.7 0.0052 16.8 0.1 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 CCC71393.1 - 8.9e-08 31.9 10.4 4.9e-07 29.5 1.2 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 CCC71393.1 - 2.2e-07 31.3 10.0 0.00024 21.6 1.9 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 CCC71393.1 - 1.4e-06 28.4 0.4 0.063 13.9 0.1 3.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 CCC71393.1 - 1.6e-06 27.4 13.0 0.00098 18.7 1.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCC71393.1 - 9.1e-06 25.9 5.5 0.00013 22.1 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 CCC71393.1 - 9.9e-05 21.8 2.3 0.3 10.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_15 PF13429.1 CCC71393.1 - 0.00038 19.6 0.9 0.00072 18.7 0.6 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat BTAD PF03704.12 CCC71393.1 - 0.0018 18.5 0.2 0.0077 16.5 0.0 2.0 1 1 1 2 2 2 1 Bacterial transcriptional activator domain Apc3 PF12895.2 CCC71393.1 - 0.0083 16.2 3.7 0.029 14.5 0.6 2.2 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 CCC71393.1 - 0.011 16.1 6.1 0.4 11.2 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1517 PF07466.6 CCC71393.1 - 0.02 13.8 0.1 0.033 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) TPR_10 PF13374.1 CCC71393.1 - 0.17 11.8 0.9 3.3 7.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCC71393.1 - 0.33 10.8 4.3 6.9 6.6 0.1 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 CCC71393.1 - 1.5 8.7 9.7 1.7 8.5 0.5 3.1 2 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain Pirin PF02678.11 CCC71394.1 - 1.4e-25 89.2 0.1 2.6e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 CCC71394.1 - 5.3e-17 61.7 0.1 1.3e-16 60.5 0.0 1.7 1 0 0 1 1 1 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 CCC71394.1 - 0.003 17.0 1.7 0.036 13.5 0.5 2.3 2 0 0 2 2 2 1 Cupin domain JSRP PF15312.1 CCC71394.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Junctional sarcoplasmic reticulum protein DNA_pol_A_exo1 PF01612.15 CCC71396.1 - 2.9e-45 153.8 0.2 7.9e-45 152.4 0.2 1.8 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 CCC71396.1 - 5.3e-27 93.9 5.3 5.9e-26 90.5 1.4 2.9 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 CCC71396.1 - 2.5e-11 43.1 0.0 6.5e-11 41.8 0.0 1.8 1 0 0 1 1 1 1 HRDC domain Ribonuclease_T2 PF00445.13 CCC71396.1 - 0.043 13.4 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 Ribonuclease T2 family NPR2 PF06218.6 CCC71397.1 - 1.2e-162 541.4 7.3 1.2e-162 541.4 5.1 1.9 2 0 0 2 2 2 1 Nitrogen permease regulator 2 HTH_23 PF13384.1 CCC71397.1 - 0.039 13.5 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Homeodomain-like domain NPR3 PF03666.8 CCC71397.1 - 0.047 12.2 10.7 0.054 12.0 0.2 3.0 3 1 0 3 3 3 0 Nitrogen Permease regulator of amino acid transport activity 3 HTH_28 PF13518.1 CCC71397.1 - 0.12 12.3 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain Kinesin PF00225.18 CCC71398.1 - 1.5e-95 319.7 11.0 2.2e-63 213.9 2.7 4.1 3 1 0 3 3 3 2 Kinesin motor domain Tweety PF04906.8 CCC71398.1 - 2.3 6.5 16.3 1 7.7 0.3 2.9 2 1 0 2 2 2 0 Tweety Cob_adeno_trans PF01923.13 CCC71398.1 - 8.9 6.0 12.8 1.4 8.6 0.9 3.4 1 1 0 2 2 2 0 Cobalamin adenosyltransferase Cpn60_TCP1 PF00118.19 CCC71399.1 - 1.3e-115 386.7 7.8 1.5e-115 386.6 5.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_I_TF PF04090.7 CCC71400.1 - 1.8e-65 219.9 0.4 3.3e-65 219.1 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase I specific initiation factor PLA2_B PF01735.13 CCC71401.1 - 1.4e-232 772.1 5.5 1.7e-232 771.8 3.8 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain TAF4 PF05236.9 CCC71402.1 - 1.1e-67 228.1 3.5 1.1e-67 228.1 2.4 1.7 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Histone PF00125.19 CCC71402.1 - 0.012 15.6 0.6 0.063 13.3 0.5 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 TFIID_30kDa PF03540.8 CCC71402.1 - 0.097 12.5 0.0 0.31 10.9 0.0 1.9 1 0 0 1 1 1 0 Transcription initiation factor TFIID 23-30kDa subunit NUFIP1 PF10453.4 CCC71403.1 - 2.1e-17 62.3 1.3 5.8e-17 60.9 0.9 1.8 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF544 PF04424.8 CCC71404.1 - 1.1e-25 89.7 0.4 1.1e-25 89.7 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF544) CCDC50_N PF15295.1 CCC71404.1 - 0.012 15.5 5.2 0.022 14.6 3.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus AlphaC_N PF08829.5 CCC71404.1 - 0.029 13.7 2.8 0.049 12.9 1.9 1.4 1 0 0 1 1 1 0 Alpha C protein N terminal RRM_1 PF00076.17 CCC71405.1 - 2.2e-10 39.9 0.1 6e-10 38.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC71405.1 - 2.1e-07 30.8 0.0 4.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC71405.1 - 0.033 14.0 0.0 0.058 13.2 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nop14 PF04147.7 CCC71405.1 - 1.4 6.7 47.5 2.8 5.7 32.9 1.4 1 0 0 1 1 1 0 Nop14-like family DUP PF00674.13 CCC71407.1 - 1.1e-20 73.5 4.6 1.1e-20 73.5 3.2 1.8 2 1 1 3 3 3 1 DUP family MBOAT PF03062.14 CCC71409.1 - 1.3e-57 195.4 20.1 2.3e-57 194.5 13.9 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family NAD_kinase PF01513.16 CCC71410.1 - 1.9e-52 177.8 0.0 2.6e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase MF_alpha_N PF05436.6 CCC71412.1 - 4.1e-22 77.6 0.1 5e-22 77.3 0.1 1.1 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus MF_alpha PF04648.7 CCC71412.1 - 1.5e-05 24.8 1.0 3.3e-05 23.8 0.7 1.6 1 0 0 1 1 1 1 Yeast mating factor alpha hormone V_ATPase_I PF01496.14 CCC71412.1 - 0.11 10.3 0.0 0.12 10.1 0.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Internalin_N PF12354.3 CCC71412.1 - 1.7 8.3 5.3 0.49 10.0 0.9 2.0 2 0 0 2 2 2 0 Bacterial adhesion/invasion protein N terminal SLY PF12485.3 CCC71413.1 - 5.7 7.1 13.6 0.34 11.1 4.6 2.2 2 0 0 2 2 2 0 Lymphocyte signaling adaptor protein RRM_1 PF00076.17 CCC71414.1 - 3e-29 100.4 0.4 2.5e-08 33.4 0.0 4.8 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC71414.1 - 4e-29 100.3 0.2 5.8e-06 26.1 0.0 4.6 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC71414.1 - 8.4e-23 79.9 0.3 2.5e-06 27.2 0.0 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 CCC71414.1 - 0.006 16.3 0.0 0.87 9.4 0.0 2.8 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 CCC71414.1 - 0.0091 15.8 0.0 0.3 10.9 0.0 2.6 2 0 0 2 2 2 1 RNA binding motif Ribosomal_L36 PF00444.13 CCC71415.1 - 4.4e-21 74.5 9.8 5.6e-21 74.2 6.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 Crust_neurohorm PF01147.12 CCC71415.1 - 0.013 14.7 1.4 0.019 14.2 1.0 1.2 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family WD40 PF00400.27 CCC71416.1 - 1.1e-23 82.1 17.0 8.5e-07 28.6 0.0 9.0 11 0 0 11 11 11 4 WD domain, G-beta repeat Nup160 PF11715.3 CCC71416.1 - 0.00073 17.8 6.7 0.098 10.7 0.1 4.1 3 1 1 4 4 4 2 Nucleoporin Nup120/160 YmzC PF14157.1 CCC71416.1 - 0.012 15.4 4.1 1.1 9.1 0.0 3.9 4 0 0 4 4 4 0 YmzC-like protein PrgU PF09627.5 CCC71416.1 - 0.043 13.4 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 PrgU-like protein TCO89 PF10452.4 CCC71417.1 - 3.3e-118 396.2 52.5 3.3e-118 396.2 36.4 2.8 2 1 0 2 2 2 1 TORC1 subunit TCO89 HMG_box PF00505.14 CCC71417.1 - 0.076 13.2 0.1 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 HMG (high mobility group) box Sec1 PF00995.18 CCC71418.1 - 1.9e-134 449.3 16.7 2.2e-134 449.1 11.6 1.0 1 0 0 1 1 1 1 Sec1 family PHD PF00628.24 CCC71419.1 - 1.1e-11 44.2 5.3 2.1e-11 43.3 3.7 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 CCC71419.1 - 0.67 9.3 4.7 1.2 8.4 3.3 1.5 1 0 0 1 1 1 0 PHD-finger FAM163 PF15069.1 CCC71419.1 - 2.8 8.5 8.9 0.47 11.0 0.3 2.9 2 2 0 2 2 2 0 FAM163 family Metallophos PF00149.23 CCC71420.1 - 3.6e-41 140.7 0.1 5.1e-41 140.2 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pterin_4a PF01329.14 CCC71421.1 - 0.1 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase Peptidase_A2B PF12384.3 CCC71422.1 - 1e-11 44.4 0.1 1.6e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 Ty3 transposon peptidase Retrotrans_gag PF03732.12 CCC71422.1 - 0.00054 19.9 0.0 0.00097 19.1 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 CCC71422.1 - 0.0031 17.3 1.4 0.0067 16.3 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle Phytoreo_P8 PF07124.6 CCC71422.1 - 0.064 11.9 0.0 0.083 11.5 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 Asp_protease_2 PF13650.1 CCC71422.1 - 0.14 12.6 0.0 0.26 11.8 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease Homeobox_KN PF05920.6 CCC71423.1 - 4.5e-18 64.6 0.5 1.2e-17 63.2 0.3 1.8 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 CCC71423.1 - 1.5e-05 24.5 1.4 1.5e-05 24.5 1.0 2.0 2 0 0 2 2 2 1 Homeobox domain DUF702 PF05142.7 CCC71423.1 - 5.2 7.2 5.9 11 6.1 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Arrestin_N PF00339.24 CCC71424.1 - 0.045 13.5 0.2 0.11 12.3 0.0 1.6 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain DAHP_synth_1 PF00793.15 CCC71425.1 - 1.6e-102 341.8 0.1 1.9e-102 341.5 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family His_biosynth PF00977.16 CCC71426.1 - 2.9e-47 160.8 0.1 1.3e-46 158.7 0.1 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 CCC71426.1 - 5.3e-28 97.7 0.0 1e-27 96.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 CCC71426.1 - 1.4e-06 28.0 0.0 3.4e-06 26.7 0.0 1.6 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 CCC71426.1 - 2.2e-05 24.2 0.0 0.00027 20.6 0.0 2.1 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 CCC71426.1 - 0.014 14.8 0.5 0.18 11.1 0.4 2.2 1 1 0 1 1 1 0 Peptidase C26 ThiG PF05690.9 CCC71426.1 - 0.02 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Dus PF01207.12 CCC71426.1 - 0.024 13.4 0.0 0.045 12.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) NMO PF03060.10 CCC71426.1 - 0.16 11.1 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase Bystin PF05291.6 CCC71427.1 - 1.1e-120 402.1 0.0 2.1e-120 401.2 0.0 1.3 1 0 0 1 1 1 1 Bystin Daxx PF03344.10 CCC71427.1 - 1.3 7.3 16.5 1.8 6.9 11.5 1.1 1 0 0 1 1 1 0 Daxx Family MMR_HSR1 PF01926.18 CCC71428.1 - 7e-17 61.4 0.3 2.2e-14 53.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCC71428.1 - 1.7e-08 33.8 0.2 2.1e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.18 CCC71428.1 - 0.00042 20.1 3.0 0.0063 16.3 0.7 3.2 2 1 0 2 2 2 1 Dynamin family DUF258 PF03193.11 CCC71428.1 - 0.0008 18.6 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 CCC71428.1 - 0.003 16.7 0.0 0.006 15.7 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 CCC71428.1 - 0.0042 17.5 0.3 0.11 13.0 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein WD40 PF00400.27 CCC71429.1 - 1.1e-05 25.0 7.2 3.4 7.7 0.1 5.4 6 0 0 6 6 6 4 WD domain, G-beta repeat SNF2_N PF00176.18 CCC71430.1 - 1.9e-81 273.1 1.0 3.5e-81 272.2 0.7 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 CCC71430.1 - 1.2e-38 131.4 2.3 1.2e-38 131.4 1.6 4.0 4 1 1 5 5 5 1 SLIDE HAND PF09110.6 CCC71430.1 - 3.1e-28 98.4 0.6 3.1e-28 98.4 0.4 4.5 5 0 0 5 5 5 1 HAND Helicase_C PF00271.26 CCC71430.1 - 1.2e-15 57.0 0.0 1e-14 54.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC71430.1 - 3.7e-08 33.4 0.0 3.7e-08 33.4 0.0 4.8 4 2 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCC71430.1 - 5e-05 22.8 0.0 0.00015 21.3 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DEAD_2 PF06733.10 CCC71430.1 - 0.02 14.2 0.3 0.02 14.2 0.2 1.9 2 0 0 2 2 2 0 DEAD_2 Glycos_transf_4 PF00953.16 CCC71431.1 - 2.7e-29 102.0 10.7 2.7e-29 102.0 7.4 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 4 Phtf-FEM1B_bdg PF12129.3 CCC71431.1 - 0.065 12.5 0.2 0.21 10.9 0.1 1.9 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor HD_3 PF13023.1 CCC71432.1 - 1.2e-34 119.4 0.3 1.6e-34 119.0 0.2 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 CCC71432.1 - 4.9e-06 26.5 0.1 9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 HD domain Sugar_tr PF00083.19 CCC71433.1 - 6.1e-95 318.4 25.1 8.2e-95 318.0 17.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC71433.1 - 1.9e-28 99.1 26.6 1.2e-22 80.1 4.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ceramidase PF05875.7 CCC71433.1 - 0.96 8.5 11.3 0.096 11.8 3.6 2.1 2 0 0 2 2 2 0 Ceramidase Zn_clus PF00172.13 CCC71434.1 - 6.3e-12 45.2 4.4 3.2e-11 42.9 3.1 2.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain tRNA_bind PF01588.15 CCC71435.1 - 3.7e-28 97.2 0.1 6.8e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.1 CCC71435.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1654 PF07867.6 CCC71435.1 - 0.097 12.0 0.1 12 5.3 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1654) PAS PF00989.19 CCC71436.1 - 8.6e-16 57.7 0.0 2.1e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 PAS fold Zn_clus PF00172.13 CCC71436.1 - 0.00031 20.5 18.3 0.00068 19.4 12.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_9 PF13426.1 CCC71436.1 - 0.0046 17.3 0.0 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 PAS domain CpeT PF06206.6 CCC71436.1 - 0.01 15.5 0.1 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 CpeT/CpcT family (DUF1001) DEAD PF00270.24 CCC71438.1 - 9.2e-43 145.6 2.1 5e-42 143.2 0.0 2.7 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC71438.1 - 2.6e-19 68.8 0.0 8.3e-19 67.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 CCC71438.1 - 4e-06 25.8 0.0 8.1e-06 24.8 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Fis1_TPR_N PF14852.1 CCC71438.1 - 0.0076 15.5 0.3 0.019 14.2 0.2 1.7 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat AAA PF00004.24 CCC71438.1 - 0.064 13.4 1.4 1.1 9.4 0.3 2.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pox_MCEL PF03291.11 CCC71439.1 - 1.9e-99 332.7 0.0 2.4e-99 332.3 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 CCC71439.1 - 4.3e-09 36.7 0.1 1.3e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCC71439.1 - 5.8e-07 29.9 0.0 1.3e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC71439.1 - 1.6e-06 27.9 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC71439.1 - 1.6e-06 27.8 0.5 3.2e-06 26.8 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC71439.1 - 2.3e-06 28.1 0.0 4e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC71439.1 - 5.9e-06 26.5 0.0 1e-05 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 CCC71439.1 - 0.00013 21.0 0.0 0.00027 20.0 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase NNMT_PNMT_TEMT PF01234.12 CCC71439.1 - 0.005 15.8 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 CCC71439.1 - 0.096 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 CCC71439.1 - 0.15 11.4 0.0 0.28 10.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AA_permease PF00324.16 CCC71440.1 - 2.8e-41 141.3 37.5 4e-41 140.8 26.0 1.2 1 0 0 1 1 1 1 Amino acid permease KH_1 PF00013.24 CCC71442.1 - 5.2e-27 93.2 0.0 2e-09 36.9 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCC71442.1 - 3.7e-20 71.1 4.5 7.2e-06 25.5 0.1 3.6 3 1 0 3 3 3 3 KH domain KH_2 PF07650.12 CCC71442.1 - 3.7e-08 32.7 1.4 0.0067 15.9 0.0 3.8 4 0 0 4 4 4 3 KH domain KH_4 PF13083.1 CCC71442.1 - 0.0055 16.3 0.0 0.34 10.5 0.0 2.5 2 0 0 2 2 2 1 KH domain dUTPase PF00692.14 CCC71442.1 - 0.098 12.1 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 dUTPase BCNT PF07572.7 CCC71443.1 - 4.1e-26 90.7 0.5 4.1e-26 90.7 0.3 2.4 3 0 0 3 3 3 1 Bucentaur or craniofacial development BtpA PF03437.10 CCC71444.1 - 0.048 12.9 0.1 0.067 12.4 0.0 1.3 1 0 0 1 1 1 0 BtpA family Glyco_hydro_31 PF01055.21 CCC71446.1 - 7.4e-136 453.4 0.1 1e-135 452.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 CCC71446.1 - 1.3e-21 76.1 0.0 4e-21 74.6 0.0 1.9 1 0 0 1 1 1 1 Galactose mutarotase-like GIY-YIG PF01541.19 CCC71447.1 - 5.4e-08 33.0 0.0 1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-rbx1 PF12678.2 CCC71447.1 - 0.065 13.3 3.1 0.16 12.1 2.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING-like PF08746.6 CCC71447.1 - 0.21 11.6 0.3 0.21 11.6 0.2 2.5 3 0 0 3 3 3 0 RING-like domain zf-RING_2 PF13639.1 CCC71447.1 - 0.45 10.3 8.4 0.1 12.4 3.1 2.0 2 1 0 2 2 2 0 Ring finger domain AAA_2 PF07724.9 CCC71448.1 - 7.3e-36 123.6 0.9 1.6e-35 122.5 0.6 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 CCC71448.1 - 1.6e-13 51.0 0.2 3.4e-13 49.9 0.2 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 CCC71448.1 - 5.7e-09 35.7 0.8 1.6e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 CCC71448.1 - 2.9e-07 30.3 0.0 7.3e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCC71448.1 - 4.6e-06 26.7 1.9 0.00015 21.8 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_17 PF13207.1 CCC71448.1 - 7.1e-06 26.8 2.1 5.7e-05 23.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 CCC71448.1 - 6.5e-05 22.9 1.1 0.00024 21.1 0.2 2.3 1 1 1 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 CCC71448.1 - 0.00015 21.0 0.0 0.01 14.9 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 CCC71448.1 - 0.00037 20.0 0.0 0.11 11.9 0.0 2.8 3 0 0 3 3 3 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 CCC71448.1 - 0.00075 18.9 0.0 0.002 17.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 CCC71448.1 - 0.0022 17.8 0.2 0.0075 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 CCC71448.1 - 0.0025 17.4 0.2 0.0062 16.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCC71448.1 - 0.0028 16.7 0.1 0.012 14.7 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 CCC71448.1 - 0.0052 16.6 0.0 0.019 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 CCC71448.1 - 0.016 14.7 0.8 0.61 9.5 0.0 3.1 2 1 2 4 4 4 0 DEAD/DEAH box helicase Sigma54_activ_2 PF14532.1 CCC71448.1 - 0.016 15.2 0.0 0.048 13.7 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 CCC71448.1 - 0.017 14.6 0.0 0.038 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 CCC71448.1 - 0.017 14.3 0.0 0.051 12.8 0.0 1.7 2 0 0 2 2 1 0 PhoH-like protein NACHT PF05729.7 CCC71448.1 - 0.019 14.6 0.1 0.14 11.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 CCC71448.1 - 0.027 14.2 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 CCC71448.1 - 0.048 12.5 0.0 0.08 11.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 CCC71448.1 - 0.063 13.5 2.2 0.082 13.2 0.0 2.2 2 1 0 2 2 2 0 ABC transporter DUF2458 PF10454.4 CCC71448.1 - 0.063 13.1 4.6 0.11 12.4 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) RNA_helicase PF00910.17 CCC71448.1 - 0.095 12.8 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 CCC71448.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 CCC71448.1 - 0.31 10.8 3.6 0.6 9.9 0.0 3.0 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 CCC71448.1 - 0.34 11.2 6.0 0.16 12.2 0.4 3.1 3 1 0 3 3 2 0 AAA domain Methyltransf_11 PF08241.7 CCC71449.1 - 0.054 13.9 0.0 0.3 11.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Tyr-DNA_phospho PF06087.7 CCC71450.1 - 3.9e-98 328.9 0.3 4.6e-98 328.7 0.2 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 CCC71450.1 - 0.0063 16.2 0.0 0.039 13.7 0.0 2.2 2 0 0 2 2 2 1 PLD-like domain AMP-binding PF00501.23 CCC71451.1 - 5.3e-70 235.9 0.0 6.7e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 CCC71451.1 - 4.7e-11 43.4 0.0 2.3e-10 41.2 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain GAF_3 PF13492.1 CCC71451.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 GAF domain Transket_pyr PF02779.19 CCC71452.1 - 1.9e-47 161.0 0.0 4.6e-47 159.8 0.0 1.6 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCC71452.1 - 2.1e-36 124.5 0.1 4.3e-36 123.5 0.1 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Acatn PF13000.2 CCC71453.1 - 7.2e-239 793.8 16.8 8.2e-239 793.6 11.7 1.0 1 0 0 1 1 1 1 Acetyl-coenzyme A transporter 1 HUN PF08729.5 CCC71454.1 - 8e-15 54.4 0.0 2.6e-14 52.8 0.0 1.9 1 0 0 1 1 1 1 HPC2 and ubinuclein domain NOA36 PF06524.7 CCC71454.1 - 6.8 5.8 9.7 14 4.8 6.7 1.4 1 0 0 1 1 1 0 NOA36 protein Kinetochor_Ybp2 PF08568.5 CCC71455.1 - 5.1e-141 471.0 14.3 6.2e-141 470.7 9.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Osmo_CC PF08946.5 CCC71455.1 - 0.81 9.7 6.0 0.16 12.0 0.7 2.6 3 0 0 3 3 3 0 Osmosensory transporter coiled coil APG12 PF04110.8 CCC71456.1 - 3.2e-31 107.3 0.1 4.8e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 CPSase_L_D2 PF02786.12 CCC71457.1 - 1.6e-81 272.5 0.1 2.9e-81 271.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 CCC71457.1 - 6.8e-65 218.1 0.0 1.2e-64 217.3 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 CCC71457.1 - 2.9e-36 123.8 0.0 6.1e-36 122.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 CCC71457.1 - 9.8e-32 109.1 0.0 1.3e-30 105.5 0.0 2.5 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 CCC71457.1 - 3.9e-29 101.9 0.0 7.4e-29 101.0 0.0 1.5 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.17 CCC71457.1 - 4.2e-19 67.9 4.7 4.2e-19 67.9 3.2 2.3 3 0 0 3 3 3 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 CCC71457.1 - 1.1e-17 63.7 0.0 2.8e-16 59.1 0.0 2.9 3 1 0 3 3 3 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 CCC71457.1 - 4.4e-15 55.9 0.1 8.2e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 CCC71457.1 - 4e-09 36.1 0.0 7.8e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 CCC71457.1 - 7.4e-09 35.1 0.0 1.6e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 CCC71457.1 - 6.9e-08 32.0 4.1 0.0033 17.0 0.2 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 CCC71457.1 - 5.2e-06 26.4 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 CCC71457.1 - 0.0003 20.3 0.0 0.0011 18.4 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_3 PF13437.1 CCC71457.1 - 0.00089 19.5 2.7 0.32 11.3 0.1 3.6 3 0 0 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 CCC71457.1 - 0.00093 18.5 3.7 0.29 10.3 0.1 2.9 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_2 PF12700.2 CCC71457.1 - 0.025 13.7 0.9 4.1 6.4 0.1 2.3 1 1 1 2 2 2 0 HlyD family secretion protein GCV_H PF01597.14 CCC71457.1 - 0.072 12.7 0.7 0.23 11.1 0.5 1.9 1 0 0 1 1 1 0 Glycine cleavage H-protein RnfC_N PF13375.1 CCC71457.1 - 0.082 12.6 3.4 0.95 9.2 0.9 2.8 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain CBS PF00571.23 CCC71458.1 - 5e-23 80.6 1.0 2.6e-06 27.1 0.1 5.4 5 0 0 5 5 5 5 CBS domain LIN37 PF15306.1 CCC71458.1 - 6 6.8 6.9 0.85 9.6 1.3 2.0 2 0 0 2 2 2 0 LIN37 NAD_binding_7 PF13241.1 CCC71459.1 - 1.2e-21 76.8 0.0 1.9e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 CCC71459.1 - 5.3e-15 54.4 0.1 1.1e-14 53.4 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 CCC71459.1 - 1.7e-10 39.6 0.1 3.9e-10 38.5 0.1 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Shikimate_DH PF01488.15 CCC71459.1 - 0.019 15.0 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF2076 PF09849.4 CCC71460.1 - 3.1e-06 27.4 7.3 3.8e-06 27.1 5.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 CCC71460.1 - 0.00037 20.3 4.5 0.00053 19.8 3.1 1.2 1 0 0 1 1 1 1 CHCH domain HlyIII PF03006.15 CCC71461.1 - 8e-53 179.1 20.4 9.7e-53 178.8 14.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4231 PF14015.1 CCC71461.1 - 0.0094 15.9 0.6 0.59 10.1 0.1 2.6 1 1 1 2 2 2 1 Protein of unknown function (DUF4231) DUF1180 PF06679.7 CCC71462.1 - 0.36 10.7 4.8 0.55 10.1 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) HSP70 PF00012.15 CCC71463.1 - 1.9e-76 257.3 4.0 2.8e-75 253.4 0.8 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 CCC71463.1 - 6.6e-10 38.0 0.0 1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein ApbA PF02558.11 CCC71464.1 - 5.3e-31 107.1 0.0 8.9e-31 106.3 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 CCC71464.1 - 7.7e-30 103.4 0.1 1.3e-29 102.7 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal NAD_Gly3P_dh_N PF01210.18 CCC71464.1 - 0.00064 19.4 0.0 0.0044 16.7 0.0 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sir1 PF11603.3 CCC71465.1 - 1.2e-06 28.6 0.2 4.3e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 Regulatory protein Sir1 RNase_P_p30 PF01876.11 CCC71467.1 - 7.6e-48 161.5 0.1 1e-47 161.1 0.1 1.2 1 0 0 1 1 1 1 RNase P subunit p30 RNase_PH PF01138.16 CCC71468.1 - 1.5e-18 67.3 0.0 3e-18 66.3 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 CCC71468.1 - 8.6e-12 44.8 0.0 1.9e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 CN_hydrolase PF00795.17 CCC71471.1 - 5.3e-27 94.3 0.0 8.2e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 CCC71471.1 - 1.2e-22 80.0 0.0 3.1e-22 78.6 0.0 1.6 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 CCC71471.1 - 0.00074 19.0 0.0 0.0015 18.0 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase Oxysterol_BP PF01237.13 CCC71472.1 - 2.6e-105 351.8 0.3 5.8e-105 350.6 0.2 1.6 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 CCC71472.1 - 1.8e-31 108.0 0.5 1.8e-31 108.0 0.3 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 CCC71472.1 - 0.024 14.8 5.7 0.74 10.0 3.9 3.1 1 1 0 1 1 1 0 Pleckstrin homology domain Nop10p PF04135.7 CCC71473.1 - 1.1e-22 79.5 0.2 1.2e-22 79.3 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Prenyltrans PF00432.16 CCC71474.1 - 1e-22 79.3 1.9 4.9e-07 29.1 0.0 4.4 5 0 0 5 5 5 3 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 CCC71474.1 - 2.3e-20 72.6 0.0 7.1e-10 38.8 0.1 5.2 3 3 2 5 5 5 3 Prenyltransferase-like Prenyltrans_2 PF13249.1 CCC71474.1 - 3.8e-20 72.3 0.0 2e-12 47.4 0.0 4.6 2 1 2 4 4 4 3 Prenyltransferase-like Cyclin PF08613.6 CCC71475.1 - 9.5e-13 48.8 0.4 1.2e-12 48.4 0.3 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 CCC71475.1 - 8.4e-09 35.0 0.5 2.2e-08 33.7 0.2 1.8 1 1 1 2 2 2 1 Cyclin, N-terminal domain Met_10 PF02475.11 CCC71476.1 - 1.8e-77 259.4 0.2 2.6e-77 258.9 0.2 1.2 1 0 0 1 1 1 1 Met-10+ like-protein PrmA PF06325.8 CCC71476.1 - 0.00059 19.0 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.11 CCC71476.1 - 0.0023 16.9 0.0 0.016 14.1 0.0 2.0 2 0 0 2 2 2 1 N2,N2-dimethylguanosine tRNA methyltransferase MethyltransfD12 PF02086.10 CCC71476.1 - 0.0063 16.0 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_18 PF12847.2 CCC71476.1 - 0.042 14.4 0.0 0.091 13.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF2570 PF10828.3 CCC71476.1 - 0.11 12.0 0.2 0.27 10.8 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) ECR1_N PF14382.1 CCC71477.1 - 2.6e-13 49.0 0.0 6e-13 47.8 0.0 1.7 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 CCC71477.1 - 0.031 14.2 0.0 0.53 10.2 0.0 2.7 2 1 0 2 2 2 0 Exosome component EXOSC1/CSL4 DS PF01916.12 CCC71478.1 - 1.2e-148 494.0 0.0 1.5e-148 493.7 0.0 1.1 1 0 0 1 1 1 1 Deoxyhypusine synthase VitD-bind_III PF09164.5 CCC71479.1 - 0.028 13.9 0.0 0.075 12.6 0.0 1.7 2 0 0 2 2 2 0 Vitamin D binding protein, domain III BSD PF03909.12 CCC71480.1 - 1.9e-25 88.3 1.4 1.8e-12 46.7 0.2 2.7 2 0 0 2 2 2 2 BSD domain TFIIH_BTF_p62_N PF08567.6 CCC71480.1 - 6.6e-23 80.1 0.4 1.6e-22 78.9 0.2 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain DUF2408 PF10303.4 CCC71480.1 - 0.55 10.3 8.0 0.16 12.1 2.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) SpoIIE PF07228.7 CCC71481.1 - 1.7e-30 106.1 0.0 2.5e-30 105.6 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 CCC71481.1 - 1.4e-10 41.0 1.4 3.5e-08 33.1 0.1 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CCC71481.1 - 2.4e-06 27.1 0.5 5.6e-06 25.9 0.3 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C MIF4G PF02854.14 CCC71482.1 - 1e-56 191.6 36.5 5.5e-30 104.3 4.0 3.6 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 CCC71482.1 - 4.3e-19 68.9 24.8 4.3e-19 68.9 17.2 2.5 1 1 1 2 2 2 1 Up-frameshift suppressor 2 Daxx PF03344.10 CCC71482.1 - 0.77 8.1 30.4 1.3 7.4 21.1 1.2 1 0 0 1 1 1 0 Daxx Family ABA_GPCR PF12430.3 CCC71483.1 - 1.9e-59 200.1 6.7 1.9e-59 200.1 4.6 2.6 2 1 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 CCC71483.1 - 1.2e-14 54.1 0.1 4.5e-14 52.2 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3735) Pkinase PF00069.20 CCC71484.1 - 9.9e-46 155.9 0.0 1.9e-45 155.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ribonuc_2-5A PF06479.7 CCC71484.1 - 7.8e-41 138.9 0.5 2.2e-40 137.4 0.3 1.9 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 CCC71484.1 - 4.1e-20 71.9 0.0 1.3e-18 67.0 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase PQQ_2 PF13360.1 CCC71484.1 - 3.9e-05 23.2 0.0 8.7e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 PQQ-like domain Kdo PF06293.9 CCC71484.1 - 0.0086 15.1 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PepSY PF03413.14 CCC71484.1 - 0.011 16.3 0.4 0.66 10.6 0.1 2.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Kinase-like PF14531.1 CCC71484.1 - 0.033 13.1 0.0 4.2 6.2 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Swi5 PF07061.6 CCC71485.1 - 2.9e-18 65.4 2.7 3.5e-18 65.1 1.8 1.2 1 0 0 1 1 1 1 Swi5 BUD22 PF09073.5 CCC71485.1 - 0.055 12.5 1.0 0.057 12.4 0.7 1.1 1 0 0 1 1 1 0 BUD22 DUF3135 PF11333.3 CCC71485.1 - 0.057 13.5 0.3 0.12 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) Spc24 PF08286.6 CCC71485.1 - 0.075 12.7 1.8 0.087 12.5 1.3 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF2458 PF10454.4 CCC71485.1 - 0.17 11.7 4.1 0.2 11.5 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) RBD-FIP PF09457.5 CCC71485.1 - 0.19 11.5 7.0 0.95 9.3 2.1 2.3 2 0 0 2 2 2 0 FIP domain Atg14 PF10186.4 CCC71485.1 - 0.64 8.8 4.6 0.81 8.5 3.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF342 PF03961.8 CCC71485.1 - 2.7 6.2 6.4 3 6.1 4.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF1497 PF07384.6 CCC71485.1 - 8 6.7 6.5 7.8 6.7 0.7 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1497) GRAM PF02893.15 CCC71486.1 - 5.9e-16 57.7 0.3 2e-15 56.0 0.0 2.1 2 0 0 2 2 2 1 GRAM domain Sas10_Utp3 PF04000.10 CCC71487.1 - 3.9e-08 33.3 0.4 3.9e-08 33.3 0.3 1.8 3 0 0 3 3 3 1 Sas10/Utp3/C1D family DUF1955 PF09205.5 CCC71487.1 - 0.85 9.1 5.4 6.1 6.3 0.5 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF1955) Pkinase PF00069.20 CCC71488.1 - 3.7e-48 163.9 0.3 2.7e-47 161.1 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71488.1 - 1.1e-23 83.6 0.2 4.4e-23 81.6 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC71488.1 - 0.032 13.2 0.0 0.058 12.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF2731 PF10806.3 CCC71489.1 - 1.7e-29 102.6 0.3 3.3e-29 101.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2731) STE PF02200.11 CCC71490.1 - 1.8e-59 198.6 3.0 3.8e-59 197.6 2.1 1.5 1 0 0 1 1 1 1 STE like transcription factor RNA_pol_3_Rpc31 PF11705.3 CCC71490.1 - 7.9e-06 25.9 5.5 2e-05 24.6 3.8 1.8 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2457 PF10446.4 CCC71490.1 - 1.8 7.2 17.2 3.7 6.1 11.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RRM_1 PF00076.17 CCC71491.1 - 1.4e-44 149.6 0.0 5.7e-16 57.9 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC71491.1 - 2.8e-27 94.4 0.0 7e-09 35.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC71491.1 - 6.4e-16 57.9 0.0 2.4e-09 36.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 CCC71491.1 - 0.0051 16.6 0.0 0.012 15.4 0.0 1.6 2 0 0 2 2 2 1 RNA binding motif SBDS PF01172.13 CCC71492.1 - 3.9e-11 42.5 0.1 4.7e-11 42.3 0.1 1.0 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Brix PF04427.13 CCC71493.1 - 6.2e-41 140.1 2.7 1.1e-40 139.3 1.9 1.4 1 0 0 1 1 1 1 Brix domain Pex19 PF04614.7 CCC71493.1 - 0.045 13.3 4.1 0.069 12.7 2.9 1.3 1 0 0 1 1 1 0 Pex19 protein family Xpo1 PF08389.7 CCC71494.1 - 5.2e-05 23.1 7.4 0.049 13.5 0.2 3.7 3 0 0 3 3 3 2 Exportin 1-like protein Gar1 PF04410.9 CCC71495.1 - 1.5e-42 144.6 5.5 1e-41 141.9 3.8 2.0 1 1 0 1 1 1 1 Gar1/Naf1 RNA binding region ING PF12998.2 CCC71496.1 - 8.5e-19 67.7 2.5 1.6e-18 66.9 1.8 1.5 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 CCC71496.1 - 4.1e-10 39.1 8.1 8.3e-10 38.2 5.6 1.5 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 CCC71496.1 - 0.0058 16.7 0.4 0.016 15.3 0.1 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-C4_Topoisom PF01396.14 CCC71496.1 - 0.15 11.5 5.3 2.8 7.5 0.4 2.6 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger tRNA-synt_1d PF00750.14 CCC71497.1 - 3.6e-105 351.6 4.8 4.7e-105 351.2 3.3 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 CCC71497.1 - 7.6e-30 103.3 0.3 1.6e-28 99.0 0.1 2.5 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 CCC71497.1 - 8.2e-09 35.8 0.0 5.2e-07 30.1 0.0 3.0 3 0 0 3 3 3 1 Arginyl tRNA synthetase N terminal domain Sugar_tr PF00083.19 CCC71498.1 - 2.2e-173 576.9 36.4 2.6e-173 576.7 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC71498.1 - 9.8e-25 86.9 32.9 2.7e-24 85.5 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2178 PF09946.4 CCC71498.1 - 0.065 12.9 3.2 2.9 7.6 1.3 2.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2178) Sugar_tr PF00083.19 CCC71499.1 - 8.8e-168 558.5 38.6 1e-167 558.3 26.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC71499.1 - 2.4e-32 112.0 47.2 2.9e-29 101.9 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pal1 PF08316.6 CCC71500.1 - 5.5e-26 91.6 0.2 5.5e-26 91.6 0.2 1.9 2 1 0 2 2 2 1 Pal1 cell morphology protein Sec23_trunk PF04811.10 CCC71501.1 - 6.2e-61 205.8 0.1 1.4e-60 204.7 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 CCC71501.1 - 6.6e-21 73.6 0.5 1.9e-20 72.2 0.4 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 CCC71501.1 - 2.3e-13 50.4 0.0 5.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 CCC71501.1 - 1e-11 44.2 6.4 2e-11 43.2 4.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 CCC71501.1 - 0.0079 15.8 0.0 0.027 14.1 0.0 1.9 2 0 0 2 2 2 1 Gelsolin repeat PGP_phosphatase PF09419.5 CCC71502.1 - 1.4e-73 245.7 0.0 1.6e-73 245.6 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 CCC71502.1 - 0.00046 19.8 0.0 0.00071 19.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 CCC71502.1 - 0.0019 18.6 0.0 0.0031 17.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1071 PF06378.6 CCC71502.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) ATP-synt_S1 PF05827.7 CCC71503.1 - 4.3e-45 154.2 0.8 6.2e-45 153.6 0.6 1.2 1 0 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Pkinase PF00069.20 CCC71504.1 - 1.1e-71 241.0 0.0 2.3e-71 239.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71504.1 - 5.3e-52 176.4 0.0 1.1e-51 175.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC71504.1 - 3.6e-07 29.4 0.1 6.7e-06 25.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 CCC71504.1 - 0.16 11.6 0.0 1.8 8.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pyr_redox_2 PF07992.9 CCC71508.1 - 7.5e-28 97.7 0.0 1.4e-27 96.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCC71508.1 - 4.9e-19 68.5 0.7 1.6e-16 60.4 0.1 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 CCC71508.1 - 1.5e-09 38.2 0.0 8.3e-07 29.2 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 CCC71508.1 - 6.3e-07 28.5 2.1 0.54 9.0 0.2 4.1 3 2 0 4 4 4 3 Glucose inhibited division protein A NAD_binding_7 PF13241.1 CCC71508.1 - 2.5e-05 24.4 0.0 0.0075 16.5 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 CCC71508.1 - 0.00012 21.3 0.2 0.0022 17.1 0.0 2.6 2 1 1 3 3 3 1 Thi4 family NAD_binding_8 PF13450.1 CCC71508.1 - 0.00024 21.0 0.0 0.029 14.3 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 CCC71508.1 - 0.00048 19.1 0.2 2.3 7.0 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase Shikimate_DH PF01488.15 CCC71508.1 - 0.0008 19.5 0.2 0.77 9.8 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 CCC71508.1 - 0.0022 16.9 0.3 1.6 7.5 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.1 CCC71508.1 - 0.0041 16.1 0.0 0.56 9.0 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 CCC71508.1 - 0.023 13.7 0.1 4.3 6.2 0.1 2.2 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 CCC71508.1 - 0.031 12.7 0.1 1.8 6.9 0.1 3.1 3 1 1 4 4 4 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 CCC71508.1 - 0.045 13.4 0.2 8.5 6.0 0.1 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Septin PF00735.13 CCC71509.1 - 6.2e-113 376.4 0.0 9.3e-113 375.9 0.0 1.3 1 0 0 1 1 1 1 Septin FtsK_SpoIIIE PF01580.13 CCC71509.1 - 4.3e-05 23.0 0.0 9.6e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 CCC71509.1 - 4.3e-05 23.4 0.0 8.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 CCC71509.1 - 0.0012 18.0 1.2 0.0031 16.7 0.1 2.2 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_24 PF13479.1 CCC71509.1 - 0.0024 17.4 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 CCC71509.1 - 0.0034 17.5 0.0 0.021 14.9 0.0 2.2 1 1 0 2 2 2 1 AAA domain NACHT PF05729.7 CCC71509.1 - 0.0035 17.0 0.0 0.0079 15.8 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 CCC71509.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain GTP_EFTU PF00009.22 CCC71509.1 - 0.018 14.4 1.3 0.14 11.5 0.0 2.7 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain Pox_A32 PF04665.7 CCC71509.1 - 0.027 13.7 0.1 0.047 12.9 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.17 CCC71509.1 - 0.028 14.5 0.0 0.064 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Miro PF08477.8 CCC71509.1 - 0.03 14.8 0.0 0.072 13.5 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_16 PF13191.1 CCC71509.1 - 0.031 14.2 0.1 0.14 12.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 CCC71509.1 - 0.088 12.2 0.1 0.84 9.1 0.0 2.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 CCC71509.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SET PF00856.23 CCC71510.1 - 0.14 12.4 0.1 0.39 10.9 0.0 1.8 2 0 0 2 2 2 0 SET domain EMP24_GP25L PF01105.19 CCC71511.1 - 2.1e-47 161.2 3.3 2.4e-47 161.0 2.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4140 PF13600.1 CCC71511.1 - 0.0033 17.8 0.1 0.005 17.2 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of unknown function (DUF4140) DUF4640 PF15480.1 CCC71511.1 - 0.039 13.5 0.5 0.36 10.3 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4640) Flavodoxin_2 PF02525.12 CCC71512.1 - 4e-52 176.6 0.0 4.6e-52 176.4 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCC71512.1 - 1.1e-10 41.1 0.0 2.7e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CCC71512.1 - 0.00021 20.6 0.0 0.00036 19.9 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin Peptidase_M18 PF02127.10 CCC71513.1 - 2.4e-175 583.2 0.0 2.7e-175 583.0 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 CCC71513.1 - 4.9e-09 35.3 0.0 1.2e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase CBM_2 PF00553.14 CCC71513.1 - 0.037 14.0 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 Cellulose binding domain RNA_pol_Rpb1_5 PF04998.12 CCC71514.1 - 1.8e-97 325.8 0.3 2.9e-97 325.2 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 CCC71514.1 - 1e-81 274.8 0.0 1.7e-81 274.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 CCC71514.1 - 6.8e-70 234.3 0.0 1.3e-69 233.3 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 CCC71514.1 - 1.7e-38 131.8 0.0 4.3e-38 130.5 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 CCC71514.1 - 5.7e-31 106.4 0.0 1.5e-30 105.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 NEP PF10167.4 CCC71514.1 - 0.064 12.9 0.0 0.2 11.3 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised conserved protein DUF2786 PF10979.3 CCC71514.1 - 0.16 11.6 0.1 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) TLD PF07534.11 CCC71515.1 - 2.4e-32 111.7 0.2 3.2e-31 108.1 0.1 2.2 1 1 0 1 1 1 1 TLD DUF4211 PF13926.1 CCC71515.1 - 0.15 11.4 0.8 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) Aldo_ket_red PF00248.16 CCC71516.1 - 3.1e-57 193.5 0.0 3.8e-57 193.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Profilin PF00235.14 CCC71517.1 - 1.9e-38 131.2 0.0 2.1e-38 131.1 0.0 1.0 1 0 0 1 1 1 1 Profilin Leo1 PF04004.8 CCC71518.1 - 4.7e-45 153.3 0.1 4.7e-45 153.3 0.1 2.8 3 0 0 3 3 3 1 Leo1-like protein GPP34 PF05719.6 CCC71519.1 - 3.4e-36 125.2 0.0 4.5e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) UCH PF00443.24 CCC71520.1 - 3.2e-61 206.8 4.9 4e-60 203.2 3.4 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 CCC71520.1 - 2.8e-40 135.5 3.3 1.2e-18 66.2 0.2 4.7 4 0 0 4 4 4 4 A repeated domain in UCH-protein UCH_1 PF13423.1 CCC71520.1 - 2.6e-10 40.2 2.5 3.3e-05 23.4 0.2 2.9 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase COQ7 PF03232.8 CCC71521.1 - 1.4e-72 242.7 0.1 1.8e-72 242.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 BCS1_N PF08740.6 CCC71522.1 - 6.5e-51 172.6 0.2 1.3e-50 171.5 0.1 1.5 1 1 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 CCC71522.1 - 4.9e-23 81.7 0.0 8.6e-23 80.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 CCC71522.1 - 0.00016 22.4 0.0 0.00033 21.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCC71522.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 CCC71522.1 - 0.0012 17.9 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_21 PF13304.1 CCC71522.1 - 0.0022 17.9 0.0 0.0036 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 CCC71522.1 - 0.0024 16.8 0.0 0.004 16.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 CCC71522.1 - 0.003 17.7 0.0 0.0097 16.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.9 CCC71522.1 - 0.003 17.2 0.0 0.012 15.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 CCC71522.1 - 0.0036 16.4 0.0 0.0081 15.2 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_14 PF13173.1 CCC71522.1 - 0.0042 16.9 0.0 0.013 15.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 CCC71522.1 - 0.0059 16.6 0.0 0.02 14.8 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 CCC71522.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 CCC71522.1 - 0.015 14.9 0.1 0.39 10.3 0.0 2.9 2 1 1 3 3 3 0 NACHT domain ABC_tran PF00005.22 CCC71522.1 - 0.016 15.5 0.0 0.038 14.2 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 CCC71522.1 - 0.017 14.8 0.0 0.059 13.0 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_29 PF13555.1 CCC71522.1 - 0.024 14.1 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 CCC71522.1 - 0.025 14.1 0.1 0.067 12.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 CCC71522.1 - 0.027 14.7 0.0 0.1 12.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CCC71522.1 - 0.034 13.9 0.0 0.11 12.2 0.0 1.9 1 1 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 CCC71522.1 - 0.039 14.1 0.0 0.16 12.1 0.0 2.1 1 0 0 1 1 1 0 RNA helicase KaiC PF06745.8 CCC71522.1 - 0.043 12.9 0.0 0.11 11.5 0.0 1.7 1 0 0 1 1 1 0 KaiC Miro PF08477.8 CCC71522.1 - 0.058 13.8 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_23 PF13476.1 CCC71522.1 - 0.09 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 CCC71522.1 - 0.11 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gram_pos_anchor PF00746.16 CCC71522.1 - 0.18 11.6 1.2 0.36 10.6 0.8 1.5 1 0 0 1 1 1 0 Gram positive anchor Lipase_GDSL_2 PF13472.1 CCC71523.1 - 1.1e-22 81.0 0.0 1.2e-22 80.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 CCC71523.1 - 1.5e-20 74.0 0.0 1.9e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RhoGAP PF00620.22 CCC71524.1 - 1.3e-41 141.7 0.4 3.7e-41 140.2 0.3 1.9 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 CCC71524.1 - 4.3e-13 49.1 28.5 1.9e-06 27.8 8.4 2.5 2 0 0 2 2 2 2 LIM domain IncA PF04156.9 CCC71524.1 - 1.3 8.5 9.0 0.97 9.0 2.5 2.6 2 0 0 2 2 2 0 IncA protein AIRC PF00731.15 CCC71525.1 - 1.7e-62 209.1 0.5 2.7e-62 208.4 0.3 1.3 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 CCC71525.1 - 8.2e-61 204.3 0.0 1.3e-60 203.6 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 CCC71525.1 - 8.8e-08 32.0 0.0 1.8e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 CCC71525.1 - 3.3e-05 23.2 0.0 6e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain 2-Hacid_dh_C PF02826.14 CCC71525.1 - 0.0012 17.9 0.0 0.0028 16.8 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Dala_Dala_lig_C PF07478.8 CCC71525.1 - 0.0027 17.1 0.0 0.018 14.4 0.0 2.2 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 CCC71525.1 - 0.022 14.6 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain TrkA_N PF02254.13 CCC71525.1 - 0.049 13.6 0.4 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Afi1 PF07792.7 CCC71526.1 - 4.1e-41 140.3 0.9 8e-41 139.4 0.1 2.0 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 CCC71526.1 - 1.5e-24 85.8 3.7 2.8e-24 84.9 0.3 2.6 2 0 0 2 2 2 1 Stabilization of polarity axis Lzipper-MIP1 PF14389.1 CCC71526.1 - 0.74 9.9 6.2 12 6.0 0.1 3.5 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Mito_carr PF00153.22 CCC71527.1 - 1.4e-61 204.1 0.2 2.6e-21 75.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_60s PF00428.14 CCC71528.1 - 6.7e-24 84.1 11.5 7.8e-24 83.8 8.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage_holin_5 PF06946.6 CCC71528.1 - 1.5 9.0 3.9 0.8 9.9 0.3 2.0 1 1 1 2 2 2 0 Phage holin HAD_2 PF13419.1 CCC71531.1 - 8.7e-16 58.6 0.0 2.3e-14 54.0 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 CCC71531.1 - 2.9e-11 44.2 0.0 5.1e-07 30.3 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 CCC71531.1 - 8.8e-10 38.1 0.0 1.7e-09 37.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 CCC71531.1 - 2.3e-05 24.6 0.0 3.6e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 CCC71531.1 - 0.011 15.1 0.0 0.66 9.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Hydrolase_3 PF08282.7 CCC71531.1 - 0.027 14.0 0.0 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NUC173 PF08161.7 CCC71531.1 - 0.12 11.7 0.3 0.57 9.4 0.2 1.9 1 1 1 2 2 2 0 NUC173 domain Vps5 PF09325.5 CCC71532.1 - 9.4e-07 28.3 10.5 2e-06 27.2 7.3 1.5 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 CCC71532.1 - 0.0025 17.5 1.1 0.0056 16.4 0.8 1.6 1 0 0 1 1 1 1 PX domain GTP_EFTU PF00009.22 CCC71533.1 - 3.6e-63 212.3 0.2 5.4e-63 211.8 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCC71533.1 - 2.1e-37 127.3 0.0 8.1e-37 125.4 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 CCC71533.1 - 3.2e-21 74.9 0.0 7.7e-21 73.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 CCC71533.1 - 2.6e-14 52.8 0.0 1.1e-13 50.8 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 CCC71533.1 - 9.4e-14 51.2 0.4 2.5e-12 46.7 0.0 3.4 4 0 0 4 4 4 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 CCC71533.1 - 2.3e-05 24.3 0.1 5.2e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SUKH-4 PF14435.1 CCC71533.1 - 0.12 12.0 0.0 0.45 10.2 0.0 2.0 1 0 0 1 1 1 0 SUKH-4 immunity protein RhoGAP PF00620.22 CCC71534.1 - 7.5e-34 116.5 0.4 1.1e-32 112.7 0.3 2.2 1 1 0 1 1 1 1 RhoGAP domain Iso_dh PF00180.15 CCC71535.1 - 7.8e-102 340.7 0.0 9.1e-102 340.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF2587 PF10759.4 CCC71535.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2587) Metallophos PF00149.23 CCC71536.1 - 2e-07 30.5 0.0 3.7e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UBA PF00627.26 CCC71537.1 - 7.2e-10 38.4 0.4 2.8e-09 36.5 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 CCC71537.1 - 0.07 12.6 0.0 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain HSF_DNA-bind PF00447.12 CCC71538.1 - 1.9e-34 117.9 4.3 1.9e-34 117.9 3.0 2.4 3 0 0 3 3 3 1 HSF-type DNA-binding Actin PF00022.14 CCC71539.1 - 4.1e-25 88.0 0.0 2.2e-19 69.1 0.0 3.3 2 1 0 2 2 2 2 Actin CPL PF08144.6 CCC71539.1 - 0.0084 15.9 0.1 0.021 14.6 0.1 1.6 1 0 0 1 1 1 1 CPL (NUC119) domain Nop14 PF04147.7 CCC71539.1 - 0.17 9.7 21.1 0.28 9.0 14.6 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 CCC71539.1 - 5.8 4.8 15.0 11 3.8 10.4 1.4 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 CCC71539.1 - 6.2 5.9 19.7 12 5.0 13.6 1.3 1 0 0 1 1 1 0 NOA36 protein CoA_binding PF02629.14 CCC71540.1 - 1.1e-25 89.9 1.6 9e-25 87.0 0.2 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 CCC71540.1 - 2.5e-23 82.3 0.4 4e-23 81.6 0.3 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 CCC71540.1 - 5.6e-07 29.2 0.0 1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 CCC71540.1 - 9.1e-05 22.6 0.0 0.00058 20.0 0.0 2.0 2 0 0 2 2 2 1 CoA binding domain Toprim_Crpt PF13342.1 CCC71540.1 - 0.067 12.8 0.1 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 C-terminal repeat of topoisomerase TPK_catalytic PF04263.11 CCC71541.1 - 2.3e-20 72.3 0.0 4.7e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 CCC71541.1 - 4.3e-14 51.9 0.1 9.3e-14 50.8 0.1 1.6 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain AAA PF00004.24 CCC71542.1 - 6.3e-05 23.1 1.5 0.00015 21.9 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 CCC71542.1 - 0.028 14.1 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Vps23_core PF09454.5 CCC71542.1 - 0.061 12.9 0.3 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Vps23 core domain Utp12 PF04003.7 CCC71543.1 - 6.9e-20 70.9 3.2 6.9e-20 70.9 2.2 1.8 2 0 0 2 2 2 1 Dip2/Utp12 Family YabP PF07873.6 CCC71543.1 - 0.0042 16.5 0.2 0.012 15.1 0.1 1.7 1 0 0 1 1 1 1 YabP family CBFD_NFYB_HMF PF00808.18 CCC71544.1 - 1.4e-12 47.4 0.4 2.3e-12 46.7 0.3 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone ICAT PF06384.6 CCC71544.1 - 0.035 13.8 0.3 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Beta-catenin-interacting protein ICAT Glyco_transf_22 PF03901.12 CCC71545.1 - 1.9e-74 251.1 35.7 2.3e-74 250.9 24.7 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family G-patch_2 PF12656.2 CCC71546.1 - 1.7e-21 75.8 0.2 1.7e-21 75.8 0.1 2.3 2 2 0 2 2 2 1 DExH-box splicing factor binding site FAM178 PF14816.1 CCC71547.1 - 0.016 13.8 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 MDM31_MDM32 PF08118.6 CCC71548.1 - 1.3e-45 155.8 18.7 1.3e-30 106.3 2.4 4.5 2 1 2 4 4 4 4 Yeast mitochondrial distribution and morphology (MDM) proteins Integrase_Zn PF02022.14 CCC71548.1 - 0.041 13.3 1.0 0.082 12.3 0.7 1.4 1 0 0 1 1 1 0 Integrase Zinc binding domain Ribosomal_L13 PF00572.13 CCC71549.1 - 2.5e-44 150.3 0.1 3e-44 150.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 RNA_pol_Rpb2_6 PF00562.23 CCC71550.1 - 9.3e-127 422.9 0.2 1.6e-126 422.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 CCC71550.1 - 1.5e-72 242.7 0.1 2.4e-72 242.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 CCC71550.1 - 9.5e-52 175.1 0.0 1.9e-51 174.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 CCC71550.1 - 6.2e-31 106.4 0.1 1.5e-30 105.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 CCC71550.1 - 2.8e-28 97.5 1.2 5.3e-28 96.6 0.3 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 CCC71550.1 - 7.5e-22 76.8 0.1 1.8e-21 75.6 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 CCC71550.1 - 1.7e-17 63.0 2.4 4.6e-17 61.7 1.7 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Zn_Tnp_IS1595 PF12760.2 CCC71550.1 - 0.23 11.2 0.1 0.46 10.3 0.1 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain TB2_DP1_HVA22 PF03134.14 CCC71551.1 - 0.015 14.9 3.6 0.062 13.0 2.5 2.0 1 1 0 1 1 1 0 TB2/DP1, HVA22 family ABC2_membrane PF01061.19 CCC71552.1 - 2.6e-86 288.1 61.0 1.5e-44 151.6 15.5 2.7 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 CCC71552.1 - 7.3e-40 136.4 0.0 9.5e-19 68.0 0.0 3.6 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 CCC71552.1 - 3.2e-39 132.7 9.2 3.2e-36 123.1 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 CCC71552.1 - 4.1e-23 81.2 0.0 9.3e-23 80.1 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 CCC71552.1 - 3.5e-08 33.1 0.0 0.00012 21.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 CCC71552.1 - 6e-07 29.6 0.8 2.7e-05 24.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain cobW PF02492.14 CCC71552.1 - 2.2e-05 23.9 1.8 0.015 14.7 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CCC71552.1 - 3.2e-05 24.2 0.2 0.042 14.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF258 PF03193.11 CCC71552.1 - 3.8e-05 22.9 0.1 0.003 16.7 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 CCC71552.1 - 4.7e-05 23.0 0.1 0.15 11.7 0.0 2.5 2 0 0 2 2 2 2 Part of AAA domain AAA_29 PF13555.1 CCC71552.1 - 0.00035 20.0 0.5 0.0049 16.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SMC_N PF02463.14 CCC71552.1 - 0.00039 19.7 0.0 0.0088 15.2 0.0 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC2_membrane_3 PF12698.2 CCC71552.1 - 0.00052 19.1 38.9 0.038 13.0 8.3 2.9 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 CCC71552.1 - 0.00075 19.3 0.0 0.036 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 CCC71552.1 - 0.0019 18.3 0.7 0.62 10.2 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 CCC71552.1 - 0.0021 18.0 1.8 0.14 12.1 0.2 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 CCC71552.1 - 0.0022 17.6 0.4 2.2 7.9 0.1 2.6 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 CCC71552.1 - 0.0023 18.7 0.0 0.63 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 CCC71552.1 - 0.0047 17.2 0.0 0.11 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 CCC71552.1 - 0.0064 16.1 0.4 0.77 9.4 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 CCC71552.1 - 0.0091 15.9 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 CCC71552.1 - 0.11 12.0 0.7 2.3 7.7 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 CCC71552.1 - 0.14 11.8 0.3 18 4.9 0.0 2.9 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.1 CCC71552.1 - 0.16 11.5 0.3 5.7 6.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 CCC71552.1 - 0.17 12.0 0.0 36 4.5 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) ISN1 PF06437.6 CCC71553.1 - 5.6e-181 601.6 0.0 6.4e-181 601.5 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase MTH865 PF07747.6 CCC71553.1 - 0.044 13.4 0.0 1.5 8.5 0.0 2.4 2 0 0 2 2 2 0 MTH865-like family Choline_transpo PF04515.7 CCC71554.1 - 3.1e-93 312.1 21.1 3.1e-93 312.1 14.6 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.8 CCC71554.1 - 0.082 12.9 1.7 0.23 11.4 1.2 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM190 PF15431.1 CCC71554.1 - 0.22 11.4 0.8 0.49 10.3 0.5 1.5 1 0 0 1 1 1 0 Transmembrane protein 190 Xpo1 PF08389.7 CCC71555.1 - 5.4e-23 81.5 3.5 5.4e-23 81.5 2.4 4.9 7 0 0 7 7 7 1 Exportin 1-like protein HEAT PF02985.17 CCC71555.1 - 0.017 15.1 0.0 6.4 7.1 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat LSM PF01423.17 CCC71556.1 - 5.8e-15 54.5 0.2 6.8e-15 54.3 0.2 1.1 1 0 0 1 1 1 1 LSM domain Peptidase_C34 PF05413.6 CCC71556.1 - 0.1 12.6 0.0 0.11 12.5 0.0 1.1 1 0 0 1 1 1 0 Putative closterovirus papain-like endopeptidase Proteasome PF00227.21 CCC71558.1 - 2.5e-47 160.6 0.1 3.6e-47 160.1 0.1 1.2 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 CCC71558.1 - 4.5e-15 54.6 0.0 9.4e-15 53.5 0.0 1.5 1 0 0 1 1 1 1 Proteasome beta subunits C terminal PINIT PF14324.1 CCC71559.1 - 8.2e-34 116.7 0.1 1.8e-33 115.6 0.0 1.6 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 CCC71559.1 - 3.7e-21 74.3 7.8 6.8e-21 73.5 5.4 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger SAP PF02037.22 CCC71559.1 - 2.5e-08 33.2 0.0 4.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-Nse PF11789.3 CCC71559.1 - 0.00016 21.1 0.6 0.00033 20.0 0.4 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 CCC71559.1 - 0.0029 17.3 0.1 0.0082 15.8 0.0 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Carn_acyltransf PF00755.15 CCC71560.1 - 1.4e-177 591.3 0.8 1.7e-177 591.1 0.6 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Ribosomal_L2_C PF03947.13 CCC71561.1 - 2.6e-48 163.0 3.5 4.8e-48 162.2 2.4 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 CCC71561.1 - 1.2e-26 92.4 0.3 3.3e-26 91.0 0.1 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain AFG1_ATPase PF03969.11 CCC71562.1 - 5.5e-73 245.8 0.0 2.8e-67 227.0 0.0 3.1 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 CCC71562.1 - 0.00065 19.7 0.5 0.13 12.2 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CCC71562.1 - 0.00096 19.3 0.0 0.0021 18.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCC71562.1 - 0.0079 16.3 0.2 0.026 14.6 0.1 1.9 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 CCC71562.1 - 0.017 14.8 0.0 0.053 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Tom37 PF10568.4 CCC71562.1 - 0.026 14.7 0.0 0.067 13.4 0.0 1.7 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein Arch_ATPase PF01637.13 CCC71562.1 - 0.026 14.2 0.1 0.14 11.8 0.1 2.1 1 1 0 1 1 1 0 Archaeal ATPase RNA_helicase PF00910.17 CCC71562.1 - 0.029 14.5 0.0 0.12 12.6 0.0 2.2 1 1 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 CCC71562.1 - 0.064 13.5 0.0 0.94 9.7 0.0 2.6 2 1 0 2 2 2 0 ABC transporter Mak10 PF04112.8 CCC71563.1 - 1.1e-39 135.3 0.0 3.8e-39 133.5 0.0 1.9 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Ribosomal_S2 PF00318.15 CCC71563.1 - 0.015 14.5 2.4 0.017 14.3 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S2 Ribosomal_L11_N PF03946.9 CCC71564.1 - 2.3e-17 62.1 0.6 6.6e-17 60.7 0.2 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 CCC71564.1 - 2.7e-11 43.4 1.1 5.4e-11 42.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain PAP1 PF08601.5 CCC71566.1 - 2.9e-47 162.0 75.1 2.1e-39 136.1 15.5 4.6 2 1 2 4 4 4 3 Transcription factor PAP1 bZIP_1 PF00170.16 CCC71566.1 - 6.7e-07 29.1 10.4 2.1e-06 27.5 7.2 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCC71566.1 - 0.0002 21.1 8.2 0.00062 19.5 5.7 1.9 1 0 0 1 1 1 1 Basic region leucine zipper Sterol_MT_C PF08498.5 CCC71567.1 - 1.3e-30 105.0 1.2 2.1e-30 104.4 0.8 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 CCC71567.1 - 7.4e-21 74.3 0.1 1.5e-20 73.3 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCC71567.1 - 7.6e-20 71.2 0.0 2.1e-19 69.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC71567.1 - 5.6e-14 52.1 0.1 1.3e-13 50.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 CCC71567.1 - 1.9e-13 50.1 0.3 2.7e-13 49.6 0.2 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 CCC71567.1 - 1.7e-12 47.6 0.1 9.9e-12 45.2 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC71567.1 - 1.4e-11 44.9 0.0 9.4e-11 42.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC71567.1 - 5.6e-10 39.4 0.0 2.3e-09 37.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 CCC71567.1 - 2.3e-09 36.6 0.0 3.8e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 CCC71567.1 - 8.6e-07 29.0 0.0 2.2e-06 27.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 CCC71567.1 - 1.4e-05 24.6 0.2 2.8e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 CCC71567.1 - 0.0013 18.4 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 CCC71567.1 - 0.0031 18.3 0.0 0.0083 16.9 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain PCMT PF01135.14 CCC71567.1 - 0.0041 16.6 0.0 0.0066 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 CCC71567.1 - 0.0048 16.0 0.0 0.028 13.5 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 CCC71567.1 - 0.0074 15.6 0.0 0.02 14.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 CCC71567.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MetW PF07021.7 CCC71567.1 - 0.084 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PX PF00787.19 CCC71568.1 - 2.4e-16 59.5 3.2 2.4e-16 59.5 0.1 2.6 3 0 0 3 3 3 1 PX domain BTV_NS2 PF04514.7 CCC71568.1 - 0.31 9.8 8.3 0.6 8.9 5.7 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Spore_III_AB PF09548.5 CCC71568.1 - 1.4 8.6 11.7 0.26 11.0 2.0 2.5 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) RNA_pol_Rpb1_5 PF04998.12 CCC71568.1 - 5.2 6.2 8.5 4.5 6.4 4.7 1.6 2 0 0 2 2 2 0 RNA polymerase Rpb1, domain 5 eIF3g PF12353.3 CCC71569.1 - 3.3e-42 143.4 5.4 4.7e-42 142.9 3.8 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 CCC71569.1 - 1.6e-12 46.8 0.0 3.7e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC71569.1 - 3.6e-08 33.1 0.1 8.7e-08 31.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC71569.1 - 6.8e-08 32.3 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L33 PF00471.15 CCC71570.1 - 0.0073 16.5 0.0 0.029 14.5 0.0 1.9 1 1 0 1 1 1 1 Ribosomal protein L33 Spt5-NGN PF03439.8 CCC71571.1 - 4.7e-21 74.3 0.0 1.5e-20 72.7 0.0 1.9 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section KOW PF00467.24 CCC71571.1 - 1.6e-19 68.7 8.6 0.0004 19.9 0.0 5.1 5 0 0 5 5 5 4 KOW motif Spt5_N PF11942.3 CCC71571.1 - 2.2e-19 69.8 11.4 2.2e-19 69.8 7.9 3.1 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal SPT6_acidic PF14632.1 CCC71571.1 - 0.0024 18.0 16.7 0.0024 18.0 11.6 2.5 1 1 1 2 2 2 1 Acidic N-terminal SPT6 SDA1 PF05285.7 CCC71571.1 - 0.0051 16.1 26.6 0.01 15.1 18.4 1.5 1 0 0 1 1 1 1 SDA1 CTD PF12815.2 CCC71571.1 - 0.024 15.0 45.0 9.3 6.7 23.4 3.7 2 1 0 2 2 2 0 Spt5 C-terminal nonapeptide repeat binding Spt4 Daxx PF03344.10 CCC71571.1 - 1.3 7.3 33.8 2.2 6.6 23.5 1.3 1 0 0 1 1 1 0 Daxx Family Nucleo_P87 PF07267.6 CCC71571.1 - 2.2 6.8 19.4 4.4 5.8 13.4 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Rad33 PF08730.5 CCC71572.1 - 6.8e-29 100.5 3.7 2.1e-16 59.8 0.1 2.1 1 1 1 2 2 2 2 Rad33 EF-hand_7 PF13499.1 CCC71572.1 - 0.0015 18.6 0.5 0.0094 16.0 0.0 2.3 2 1 0 2 2 2 1 EF-hand domain pair EMP24_GP25L PF01105.19 CCC71573.1 - 1.1e-41 142.5 0.0 1.3e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD UBA_4 PF14555.1 CCC71574.1 - 3.8e-11 42.3 0.2 9.6e-11 41.0 0.1 1.8 2 0 0 2 2 2 1 UBA-like domain UBX PF00789.15 CCC71574.1 - 8.9e-11 41.7 0.0 6.2e-10 38.9 0.0 2.3 2 1 0 2 2 2 1 UBX domain IncA PF04156.9 CCC71574.1 - 0.67 9.5 10.0 1.9 8.0 6.9 1.7 1 0 0 1 1 1 0 IncA protein Methyltransf_11 PF08241.7 CCC71575.1 - 1.9e-12 47.4 0.0 3.9e-12 46.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 CCC71575.1 - 2.6e-06 27.1 0.0 3.8e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCC71575.1 - 3.6e-06 27.3 0.4 1.1e-05 25.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC71575.1 - 5.9e-05 23.3 0.0 0.00011 22.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC71575.1 - 0.00011 22.0 1.2 0.00049 19.8 0.8 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC71575.1 - 0.0006 20.3 0.0 0.0011 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain RIC3 PF15361.1 CCC71575.1 - 0.13 12.5 1.5 0.19 11.9 1.0 1.2 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Herpes_DNAp_acc PF04929.7 CCC71575.1 - 0.23 10.4 4.3 0.3 10.0 3.0 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Fer4_18 PF13746.1 CCC71575.1 - 2.5 8.6 4.7 11 6.5 3.2 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Metallophos PF00149.23 CCC71576.1 - 5.1e-39 133.7 0.2 9.4e-39 132.8 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_1 PF00076.17 CCC71577.1 - 0.098 12.3 0.1 8.6 6.0 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EamA PF00892.15 CCC71578.1 - 1.5e-09 37.9 21.0 1.3e-07 31.7 1.2 3.6 3 1 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 CCC71578.1 - 1.3e-08 34.6 21.2 0.00025 20.7 6.5 3.1 3 0 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 CCC71578.1 - 8.2e-05 22.7 23.8 0.00024 21.2 0.7 3.2 3 0 0 3 3 3 2 Multidrug resistance efflux transporter UAA PF08449.6 CCC71578.1 - 0.00032 19.7 13.0 0.00032 19.7 9.0 1.8 2 0 0 2 2 2 1 UAA transporter family Internalin_N PF12354.3 CCC71578.1 - 1.6 8.4 4.4 31 4.2 0.0 3.9 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal OST3_OST6 PF04756.8 CCC71579.1 - 1e-19 70.6 10.4 1.6e-19 70.0 7.2 1.3 1 0 0 1 1 1 1 OST3 / OST6 family DUF3801 PF12687.2 CCC71579.1 - 0.23 11.0 0.0 4.5 6.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3801) UDG PF03167.14 CCC71581.1 - 4.7e-27 94.3 0.0 6.5e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Pribosyltran PF00156.22 CCC71582.1 - 4.3e-18 65.2 0.0 6.6e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 CCC71582.1 - 0.0038 16.4 0.0 0.0049 16.1 0.0 1.1 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Nse5 PF08691.5 CCC71583.1 - 8.4e-122 407.2 22.3 1e-121 406.9 15.5 1.0 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 Ribosomal_S17e PF00833.13 CCC71584.1 - 1e-56 189.9 0.4 1.2e-56 189.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal S17 Ribosomal_L4 PF00573.17 CCC71585.1 - 9.4e-47 158.8 0.0 1.2e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_S13 PF00416.17 CCC71586.1 - 1.7e-42 144.2 2.2 2e-42 143.9 1.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 CCC71586.1 - 0.00062 18.4 0.0 0.0008 18.0 0.0 1.2 1 1 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 CCC71586.1 - 0.085 12.9 0.3 0.6 10.2 0.1 2.2 2 1 0 2 2 2 0 Helix-hairpin-helix motif Homeobox PF00046.24 CCC71587.1 - 7.3e-18 63.9 3.9 1.8e-17 62.7 2.7 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 CCC71587.1 - 0.00073 19.1 0.1 0.0023 17.5 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Sad1_UNC PF07738.8 CCC71588.1 - 4.2e-32 110.7 0.1 8.9e-32 109.7 0.1 1.6 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal AhpC-TSA PF00578.16 CCC71589.1 - 3.1e-35 120.5 0.1 1.7e-34 118.1 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 CCC71589.1 - 2.1e-17 62.9 0.1 3.6e-17 62.2 0.0 1.3 2 0 0 2 2 2 1 Redoxin 1-cysPrx_C PF10417.4 CCC71589.1 - 1.2e-08 34.4 0.2 2.5e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin ubiquitin PF00240.18 CCC71590.1 - 0.00039 19.7 0.0 0.0011 18.2 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 CCC71590.1 - 0.0086 15.7 4.3 2.3 7.9 0.0 3.9 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like HIG_1_N PF04588.8 CCC71591.1 - 5.1e-21 74.1 1.9 6.9e-21 73.7 1.3 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region IncA PF04156.9 CCC71591.1 - 0.0015 18.1 3.5 0.0024 17.4 2.5 1.4 1 0 0 1 1 1 1 IncA protein M PF02370.11 CCC71591.1 - 0.03 14.6 0.6 0.03 14.6 0.4 3.7 3 1 0 3 3 3 0 M protein repeat DUF342 PF03961.8 CCC71591.1 - 0.11 10.9 3.7 0.12 10.7 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Vps5 PF09325.5 CCC71591.1 - 0.19 10.9 11.1 0.24 10.6 7.7 1.2 1 0 0 1 1 1 0 Vps5 C terminal like DUF4140 PF13600.1 CCC71591.1 - 0.26 11.7 7.2 0.56 10.6 5.0 1.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Cauli_AT PF03233.8 CCC71591.1 - 0.4 10.3 4.2 0.62 9.7 2.9 1.2 1 0 0 1 1 1 0 Aphid transmission protein DUF2361 PF10153.4 CCC71591.1 - 1.2 9.4 9.1 1.7 8.8 6.3 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) TMCO5 PF14992.1 CCC71591.1 - 3.6 6.6 11.2 4.6 6.3 7.8 1.1 1 0 0 1 1 1 0 TMCO5 family Atg14 PF10186.4 CCC71591.1 - 7.1 5.4 9.2 9 5.1 6.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ndc1_Nup PF09531.5 CCC71592.1 - 4e-97 326.0 19.0 1.3e-96 324.4 13.1 1.7 1 1 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Rad52_Rad22 PF04098.10 CCC71593.1 - 2.3e-55 186.5 0.0 3.9e-55 185.8 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein MSC PF09402.5 CCC71594.1 - 4.7e-102 341.1 6.4 2e-101 339.0 4.4 2.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 CCC71594.1 - 1.2e-12 47.1 0.2 3.3e-12 45.7 0.1 1.8 1 0 0 1 1 1 1 HeH/LEM domain MHC_I PF00129.13 CCC71594.1 - 0.0096 15.2 0.1 0.026 13.8 0.0 1.7 1 0 0 1 1 1 1 Class I Histocompatibility antigen, domains alpha 1 and 2 UPF0118 PF01594.11 CCC71594.1 - 0.14 11.0 1.3 4 6.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF20 A_deaminase PF00962.17 CCC71595.1 - 3.8e-120 400.7 0.1 5.5e-120 400.2 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase CGI-121 PF08617.5 CCC71596.1 - 1.5e-42 144.9 0.2 1.7e-42 144.8 0.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 TPT PF03151.11 CCC71598.1 - 2e-42 144.4 0.4 2e-42 144.4 0.3 2.6 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 CCC71598.1 - 2.7e-09 36.3 14.7 2.3e-08 33.3 4.7 2.7 2 1 0 2 2 2 2 UAA transporter family Nuc_sug_transp PF04142.10 CCC71598.1 - 1.4e-08 34.1 1.9 7.9e-05 21.8 0.9 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.15 CCC71598.1 - 9.1e-05 22.4 19.1 0.0018 18.2 4.5 3.3 4 0 0 4 4 4 2 EamA-like transporter family EmrE PF13536.1 CCC71598.1 - 0.00021 21.4 1.1 0.00021 21.4 0.7 3.1 4 1 0 4 4 4 1 Multidrug resistance efflux transporter S-antigen PF05756.6 CCC71598.1 - 0.014 15.3 0.7 0.17 11.8 0.2 2.8 2 0 0 2 2 2 0 S-antigen protein UPF0546 PF10639.4 CCC71598.1 - 0.15 11.8 12.0 1.4 8.8 0.5 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 DUF3753 PF12575.3 CCC71598.1 - 0.37 10.6 10.2 2.2 8.1 0.0 4.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3753) zf-C2H2_4 PF13894.1 CCC71599.1 - 2e-05 24.5 15.4 0.0043 17.2 0.8 4.3 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCC71599.1 - 2.5e-05 24.3 14.3 0.0023 18.1 1.6 4.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC71599.1 - 0.00044 20.4 13.1 0.0017 18.5 0.5 3.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-DHHC PF01529.15 CCC71599.1 - 0.091 12.1 2.9 0.16 11.3 0.3 2.4 2 0 0 2 2 2 0 DHHC palmitoyltransferase zf-C2H2_6 PF13912.1 CCC71599.1 - 0.22 11.4 3.1 1.6 8.7 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-BED PF02892.10 CCC71599.1 - 0.72 9.6 5.4 0.22 11.3 0.2 2.8 3 0 0 3 3 3 0 BED zinc finger HNH PF01844.18 CCC71599.1 - 1.5 8.7 6.8 16 5.4 0.2 3.0 2 1 0 2 2 2 0 HNH endonuclease Glyco_hydro_76 PF03663.9 CCC71600.1 - 4.6e-153 509.9 29.8 6e-153 509.5 20.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF2347 PF09804.4 CCC71601.1 - 1.4e-58 198.4 1.6 3.9e-57 193.6 1.1 2.1 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 CCC71601.1 - 2.7e-16 60.1 0.1 5.1e-08 33.2 0.0 2.8 1 1 1 2 2 2 2 Domain of unknown function (DUF4484) Avl9 PF09794.4 CCC71601.1 - 8.3e-13 47.5 0.3 3.6e-12 45.4 0.2 1.8 1 1 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 CCC71601.1 - 6e-06 25.9 0.4 1.1e-05 25.1 0.3 1.4 1 0 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.7 CCC71601.1 - 0.026 14.5 0.4 0.054 13.5 0.3 1.5 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking F_bP_aldolase PF01116.15 CCC71602.1 - 2.2e-95 319.0 0.1 2.5e-95 318.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Peptidase_C26 PF07722.8 CCC71602.1 - 0.097 12.0 0.0 0.66 9.3 0.0 2.0 2 0 0 2 2 2 0 Peptidase C26 DWNN PF08783.6 CCC71603.1 - 1.3e-32 111.5 0.8 1.7e-31 107.9 0.0 2.4 2 0 0 2 2 2 1 DWNN domain zf-Nse PF11789.3 CCC71603.1 - 3.7e-06 26.3 0.8 3.7e-06 26.3 0.6 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 CCC71603.1 - 0.00052 19.9 0.0 0.0014 18.5 0.0 1.8 1 0 0 1 1 1 1 U-box domain zf-CCHC_2 PF13696.1 CCC71603.1 - 0.00064 19.1 5.4 0.00078 18.8 2.7 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.18 CCC71603.1 - 0.0028 17.4 3.0 0.0028 17.4 2.0 2.6 3 0 0 3 3 3 1 Zinc knuckle Rubredoxin PF00301.15 CCC71603.1 - 0.0029 17.4 2.1 2.5 8.0 0.0 3.3 3 0 0 3 3 3 2 Rubredoxin Zn_Tnp_IS1595 PF12760.2 CCC71603.1 - 0.027 14.2 0.3 1.2 8.9 0.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-CCHC_3 PF13917.1 CCC71603.1 - 0.033 13.9 0.2 0.076 12.7 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle PYNP_C PF07831.8 CCC71603.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain TF_Zn_Ribbon PF08271.7 CCC71603.1 - 0.073 12.4 2.8 0.29 10.4 0.0 2.7 2 0 0 2 2 2 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.6 CCC71603.1 - 0.22 11.1 1.2 0.57 9.8 0.1 2.1 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zf-CCHC_5 PF14787.1 CCC71603.1 - 0.4 10.2 3.0 0.69 9.4 0.2 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF1610 PF07754.6 CCC71603.1 - 5.5 7.2 8.0 0.6 10.2 1.0 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF1610) TFIIA_gamma_C PF02751.9 CCC71604.1 - 1.1e-25 89.1 1.3 1.7e-25 88.6 0.9 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 CCC71604.1 - 2.4e-25 87.8 0.2 3.2e-25 87.4 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TCTP PF00838.12 CCC71605.1 - 1.8e-69 232.9 0.4 2.1e-69 232.7 0.3 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein adh_short PF00106.20 CCC71606.1 - 1.6e-15 57.4 0.0 3.8e-07 30.1 0.0 3.2 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 CCC71606.1 - 1e-08 35.2 0.0 1.9e-08 34.3 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCC71606.1 - 0.00024 20.8 0.0 0.97 9.0 0.0 3.3 3 0 0 3 3 3 1 KR domain Epimerase PF01370.16 CCC71606.1 - 0.046 13.1 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family HAD PF12710.2 CCC71606.1 - 0.062 13.4 0.2 0.096 12.8 0.1 1.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF161 PF02588.10 CCC71606.1 - 0.93 9.8 3.8 2.9 8.2 0.7 2.3 2 0 0 2 2 2 0 Uncharacterized BCR, YitT family COG1284 PGAP1 PF07819.8 CCC71607.1 - 5.1e-07 29.5 0.1 2.1e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 PGAP1-like protein DUF676 PF05057.9 CCC71607.1 - 2.6e-06 26.8 0.0 6.6e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.6 CCC71607.1 - 0.00017 20.7 0.2 0.0015 17.7 0.0 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_1 PF00561.15 CCC71607.1 - 0.00054 19.5 0.0 0.00074 19.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 CCC71607.1 - 0.003 16.5 0.0 0.0063 15.5 0.0 1.5 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 CCC71607.1 - 0.051 13.4 0.0 0.079 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 CCC71607.1 - 0.092 12.4 0.0 0.2 11.4 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family BLOC1_2 PF10046.4 CCC71608.1 - 0.0025 17.9 6.5 0.006 16.7 4.4 1.7 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Muted PF14942.1 CCC71608.1 - 0.0033 17.3 4.6 0.0033 17.3 3.2 1.7 1 1 1 2 2 2 2 Organelle biogenesis, Muted-like protein ALIX_LYPXL_bnd PF13949.1 CCC71608.1 - 0.0036 16.3 6.6 0.0043 16.0 4.6 1.1 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Tropomyosin_1 PF12718.2 CCC71608.1 - 0.028 14.2 8.3 0.04 13.7 5.8 1.2 1 0 0 1 1 1 0 Tropomyosin like AF0941-like PF14591.1 CCC71608.1 - 0.069 13.2 0.8 0.069 13.2 0.5 2.0 2 1 0 2 2 2 0 AF0941-like DrrA_P4M PF14860.1 CCC71608.1 - 0.081 12.6 3.1 0.29 10.8 2.2 1.8 1 1 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain DUF4463 PF14703.1 CCC71608.1 - 0.086 13.3 1.7 0.11 13.0 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4463) RICH PF05062.7 CCC71608.1 - 0.1 12.7 6.2 0.068 13.3 2.5 2.0 1 1 0 2 2 2 0 RICH domain NdhM PF10664.4 CCC71608.1 - 0.12 12.2 1.0 0.35 10.7 0.4 2.0 1 1 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M Brr6_like_C_C PF10104.4 CCC71608.1 - 0.13 11.7 1.9 0.58 9.6 0.1 2.0 1 1 1 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain STAT_alpha PF01017.15 CCC71608.1 - 0.39 10.4 6.6 0.29 10.8 3.1 1.7 1 1 1 2 2 2 0 STAT protein, all-alpha domain cwf21 PF08312.7 CCC71608.1 - 0.46 10.3 2.7 0.55 10.1 0.8 2.0 2 0 0 2 2 2 0 cwf21 domain V_ATPase_I PF01496.14 CCC71608.1 - 0.56 7.9 7.3 0.57 7.9 5.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Lebercilin PF15619.1 CCC71608.1 - 1.3 8.4 10.1 0.31 10.4 4.3 1.8 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF848 PF05852.6 CCC71608.1 - 1.6 8.5 7.4 2.5 7.9 3.0 2.1 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) SPX PF03105.14 CCC71608.1 - 2.1 8.0 7.4 2.5 7.8 5.1 1.2 1 0 0 1 1 1 0 SPX domain CUE PF02845.11 CCC71609.1 - 9.2e-06 25.0 0.0 1.9e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 CUE domain UPF0203 PF05254.7 CCC71610.1 - 3.2e-28 97.3 1.9 4.5e-28 96.9 1.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 CCC71610.1 - 0.16 11.7 1.8 5.6 6.8 0.5 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 CCC71610.1 - 0.36 10.9 1.6 19 5.3 0.1 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 UCR_hinge PF02320.11 CCC71610.1 - 0.52 10.2 2.8 3.4 7.6 2.0 2.0 1 1 0 1 1 1 0 Ubiquinol-cytochrome C reductase hinge protein DASH_Ask1 PF08655.5 CCC71611.1 - 4.7e-27 93.6 0.8 9.6e-27 92.6 0.6 1.6 1 0 0 1 1 1 1 DASH complex subunit Ask1 DUF1387 PF07139.6 CCC71611.1 - 0.047 13.2 14.8 0.086 12.4 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Frag1 PF10277.4 CCC71612.1 - 2e-78 262.7 24.5 2.5e-78 262.4 17.0 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3844 PF12955.2 CCC71612.1 - 0.11 12.6 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3844) EVC2_like PF12297.3 CCC71612.1 - 0.24 9.9 0.1 0.33 9.5 0.1 1.1 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein SOG2 PF10428.4 CCC71613.1 - 0.017 13.7 1.9 0.021 13.4 1.3 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein PI3K_1B_p101 PF10486.4 CCC71613.1 - 0.093 10.2 2.7 0.1 10.1 1.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DUF1682 PF07946.9 CCC71613.1 - 0.63 8.8 10.3 0.83 8.4 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Peptidase_S49_N PF08496.5 CCC71613.1 - 2 8.1 5.3 3.4 7.4 3.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4337 PF14235.1 CCC71613.1 - 2.8 7.7 5.8 4.2 7.1 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3812 PF12757.2 CCC71614.1 - 2.9e-15 56.3 7.0 2.9e-15 56.3 4.9 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF3812) Histone PF00125.19 CCC71615.1 - 9.7e-26 89.7 0.2 1.8e-25 88.8 0.2 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 CCC71615.1 - 0.033 14.3 0.5 0.093 12.9 0.1 1.9 2 0 0 2 2 2 0 Kinetochore component CENP-S Spt5_N PF11942.3 CCC71615.1 - 0.045 14.3 20.8 0.44 11.1 1.7 2.4 1 1 1 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Actin PF00022.14 CCC71616.1 - 7.2e-23 80.6 0.6 3.9e-21 74.9 0.1 2.8 2 1 0 2 2 2 1 Actin PilM_2 PF11104.3 CCC71616.1 - 5.2e-05 22.3 0.0 0.053 12.3 0.0 2.3 2 0 0 2 2 2 2 Type IV pilus assembly protein PilM; FtsA PF14450.1 CCC71616.1 - 0.017 14.9 0.1 0.035 13.9 0.1 1.6 1 0 0 1 1 1 0 Cell division protein FtsA MreB_Mbl PF06723.8 CCC71616.1 - 0.018 13.6 0.1 11 4.5 0.0 3.0 3 0 0 3 3 3 0 MreB/Mbl protein CMV_1a PF12467.3 CCC71616.1 - 0.03 14.7 0.3 0.06 13.7 0.2 1.4 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family BBS2_N PF14781.1 CCC71616.1 - 0.063 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Pkinase PF00069.20 CCC71617.1 - 2e-42 145.1 0.0 5.8e-42 143.6 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71617.1 - 3.8e-19 68.7 0.1 4.2e-15 55.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 CCC71617.1 - 8.9e-07 28.1 0.0 3.1e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 CCC71617.1 - 0.0012 18.5 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family zf-H2C2_2 PF13465.1 CCC71618.1 - 3e-09 36.7 13.8 1.2e-06 28.4 1.8 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 CCC71618.1 - 1.1e-08 34.9 12.3 0.00063 19.9 1.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC71618.1 - 4e-08 33.0 11.6 0.00049 20.2 1.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 CCC71618.1 - 0.00057 19.5 4.5 0.034 13.9 0.4 3.0 2 0 0 2 2 2 2 BED zinc finger zf-C2H2_jaz PF12171.3 CCC71618.1 - 0.0075 16.3 10.1 0.09 12.9 2.6 2.8 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding GAGA PF09237.6 CCC71618.1 - 0.051 13.1 1.9 0.95 9.0 0.2 2.6 1 1 1 2 2 2 0 GAGA factor zf-Di19 PF05605.7 CCC71618.1 - 0.22 11.6 4.0 0.42 10.7 2.8 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 CCC71618.1 - 0.55 10.3 7.5 1.1 9.4 1.4 2.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 CCC71618.1 - 0.84 9.6 7.4 0.64 10.0 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 CCC71618.1 - 2.4 8.4 7.3 1.5 9.1 1.4 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-H2C2_5 PF13909.1 CCC71618.1 - 6.8 7.1 11.2 7.2 7.0 1.6 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Serglycin PF04360.7 CCC71619.1 - 0.034 13.8 3.7 0.044 13.5 2.0 1.7 1 1 1 2 2 2 0 Serglycin DDHD PF02862.12 CCC71619.1 - 1.3 8.7 11.4 1.9 8.2 7.9 1.2 1 0 0 1 1 1 0 DDHD domain Period_C PF12114.3 CCC71619.1 - 2 7.9 13.2 0.74 9.3 0.7 2.1 1 1 1 2 2 2 0 Period protein 2/3C-terminal region Borrelia_P83 PF05262.6 CCC71619.1 - 2.6 6.1 18.1 2.9 6.0 12.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CorA PF01544.13 CCC71620.1 - 5.9e-39 133.8 3.5 1e-20 73.9 0.3 3.4 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein Bap31 PF05529.7 CCC71621.1 - 2.3e-45 154.4 1.1 2.7e-45 154.2 0.8 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Lip_prot_lig_C PF10437.4 CCC71621.1 - 0.0028 17.2 0.2 0.0046 16.6 0.1 1.3 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus Sec2p PF06428.6 CCC71621.1 - 0.008 16.0 3.1 0.012 15.4 2.2 1.3 1 0 0 1 1 1 1 GDP/GTP exchange factor Sec2p BMFP PF04380.8 CCC71621.1 - 0.072 13.2 0.1 0.11 12.6 0.1 1.3 1 0 0 1 1 1 0 Membrane fusogenic activity RBD-FIP PF09457.5 CCC71621.1 - 0.12 12.2 0.9 0.24 11.2 0.6 1.5 1 0 0 1 1 1 0 FIP domain HJURP_mid PF12346.3 CCC71621.1 - 0.12 12.5 0.4 0.18 11.9 0.3 1.3 1 0 0 1 1 1 0 Holliday junction recognition protein-associated repeat Arabinose_bd PF12625.2 CCC71621.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Arabinose-binding domain of AraC transcription regulator, N-term SHP PF03579.8 CCC71621.1 - 1.3 8.4 9.0 3.6 7.0 0.1 2.8 3 0 0 3 3 3 0 Small hydrophobic protein NDK PF00334.14 CCC71623.1 - 8.3e-55 184.2 0.0 9.5e-55 184.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase SRF-TF PF00319.13 CCC71624.1 - 1.7e-25 88.0 0.4 2.5e-25 87.4 0.2 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Nucleoporin_FG PF13634.1 CCC71625.1 - 1.9e-43 147.2 372.7 9.5e-11 41.9 36.4 10.4 1 1 8 10 10 10 8 Nucleoporin FG repeat region Nucleoporin2 PF04096.9 CCC71625.1 - 3.1e-39 134.0 0.0 6.2e-39 133.0 0.0 1.5 1 0 0 1 1 1 1 Nucleoporin autopeptidase DUF572 PF04502.8 CCC71625.1 - 0.84 8.7 9.9 2.2 7.4 6.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF572) zf-CCCH PF00642.19 CCC71626.1 - 1.1e-18 66.3 15.9 3.7e-09 36.0 1.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Nepo_coat_N PF03689.10 CCC71626.1 - 0.031 14.0 0.0 0.068 12.8 0.0 1.5 1 0 0 1 1 1 0 Nepovirus coat protein, N-terminal domain zf-CCCH_2 PF14608.1 CCC71626.1 - 0.11 12.4 12.5 0.51 10.4 0.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Siah-Interact_N PF09032.6 CCC71626.1 - 9.8 6.3 8.1 5.5 7.1 1.5 2.4 2 0 0 2 2 2 0 Siah interacting protein, N terminal V-ATPase_C PF03223.10 CCC71627.1 - 8e-120 400.1 1.7 9e-120 399.9 1.2 1.0 1 0 0 1 1 1 1 V-ATPase subunit C NUC130_3NT PF08158.7 CCC71627.1 - 0.0018 18.5 0.2 0.97 9.7 0.0 2.7 2 0 0 2 2 2 2 NUC130/3NT domain Kinesin PF00225.18 CCC71628.1 - 5.1e-45 153.6 2.9 5.1e-45 153.6 2.0 2.5 2 1 1 3 3 3 1 Kinesin motor domain Cep57_CLD_2 PF14197.1 CCC71628.1 - 0.023 14.6 1.5 0.023 14.6 1.1 3.9 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 OB_NTP_bind PF07717.11 CCC71629.1 - 3.7e-18 65.4 0.0 8.9e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 CCC71629.1 - 4e-18 65.3 0.0 8.9e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 CCC71629.1 - 2.6e-11 43.2 0.0 6.6e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCC71629.1 - 5.3e-08 32.5 0.1 9.5e-08 31.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 CCC71629.1 - 3.2e-06 27.3 0.0 8e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 CCC71629.1 - 0.00064 19.4 0.1 0.002 17.8 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_29 PF13555.1 CCC71629.1 - 0.006 16.0 0.9 0.01 15.3 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.17 CCC71629.1 - 0.0075 15.7 0.0 0.034 13.5 0.0 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_25 PF13481.1 CCC71629.1 - 0.049 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 CCC71629.1 - 0.059 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Septin T2SE PF00437.15 CCC71629.1 - 0.074 11.9 0.1 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.1 CCC71629.1 - 0.076 12.5 0.3 1.4 8.4 0.0 2.4 1 1 0 2 2 2 0 AAA domain DUF2075 PF09848.4 CCC71629.1 - 0.095 11.6 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 CCC71629.1 - 0.47 10.7 2.0 1 9.6 0.3 2.3 2 1 0 2 2 1 0 ABC transporter AAA_23 PF13476.1 CCC71629.1 - 0.51 10.6 3.2 0.28 11.4 0.6 1.9 1 1 1 2 2 2 0 AAA domain Sen15 PF09631.5 CCC71630.1 - 8.6e-28 96.5 0.1 9.9e-28 96.3 0.0 1.0 1 0 0 1 1 1 1 Sen15 protein DUF4448 PF14610.1 CCC71631.1 - 1.3e-58 197.6 0.5 1.9e-58 197.0 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Phage_holin_6 PF10746.4 CCC71631.1 - 0.075 12.7 0.5 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 Phage holin family 6 DUF3290 PF11694.3 CCC71631.1 - 0.11 12.2 0.1 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) RRM_5 PF13893.1 CCC71633.1 - 0.0011 18.7 0.0 0.016 15.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 CCC71633.1 - 0.079 12.5 0.1 0.74 9.4 0.0 2.6 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC71633.1 - 0.12 12.3 0.0 1 9.4 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HSP70 PF00012.15 CCC71634.1 - 1.8e-45 155.0 1.0 1.8e-45 155.0 0.7 3.2 3 0 0 3 3 3 2 Hsp70 protein DUF3135 PF11333.3 CCC71634.1 - 0.0032 17.5 1.2 1.1 9.5 0.0 4.3 4 0 0 4 4 4 1 Protein of unknown function (DUF3135) IncA PF04156.9 CCC71635.1 - 0.21 11.1 3.3 0.43 10.1 2.3 1.5 1 0 0 1 1 1 0 IncA protein GAF_2 PF13185.1 CCC71636.1 - 2.3e-05 24.9 0.0 3.3e-05 24.4 0.0 1.2 1 1 0 1 1 1 1 GAF domain BOP1NT PF08145.7 CCC71637.1 - 1.9e-101 339.2 7.7 3.5e-101 338.3 5.4 1.5 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 CCC71637.1 - 4e-27 93.0 6.2 3e-11 42.7 0.3 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat UCR_TM PF02921.9 CCC71638.1 - 0.16 12.2 0.5 0.23 11.6 0.4 1.3 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region EF1G PF00647.14 CCC71639.1 - 7.1e-48 160.7 0.1 1.4e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 CCC71639.1 - 3.7e-11 42.8 0.1 1.2e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 CCC71639.1 - 1.7e-09 37.7 0.0 4e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCC71639.1 - 9.3e-06 25.4 0.1 2e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCC71639.1 - 2.2e-05 24.6 0.0 4.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 CCC71639.1 - 0.01 15.7 0.0 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 CCC71639.1 - 0.026 14.9 0.1 0.058 13.8 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ank_2 PF12796.2 CCC71640.1 - 1.5e-19 70.0 0.6 6.6e-09 36.0 0.1 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 CCC71640.1 - 1.7e-19 69.8 17.3 9.6e-07 29.1 0.2 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 CCC71640.1 - 5.5e-17 60.6 6.9 2.6e-06 26.9 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 CCC71640.1 - 8.5e-12 44.9 0.8 5.8e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 CCC71640.1 - 3.9e-09 35.8 6.9 0.14 12.4 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat zf-CHY PF05495.7 CCC71641.1 - 3.5e-15 55.8 13.1 6.1e-15 55.1 9.1 1.4 1 0 0 1 1 1 1 CHY zinc finger zf-Sec23_Sec24 PF04810.10 CCC71641.1 - 0.03 13.8 0.5 0.03 13.8 0.4 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger HypA PF01155.14 CCC71641.1 - 0.93 9.2 4.9 1.9 8.2 3.2 1.8 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-RING_3 PF14369.1 CCC71641.1 - 2.9 7.9 11.0 1.5 8.9 2.3 2.9 3 1 0 3 3 3 0 zinc-finger Zn_ribbon_recom PF13408.1 CCC71641.1 - 5.9 7.2 10.7 0.26 11.5 1.1 2.3 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain Ldh_1_C PF02866.13 CCC71642.1 - 3.9e-48 163.4 0.2 5.8e-48 162.9 0.2 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 CCC71642.1 - 1.1e-44 151.7 0.0 1.6e-44 151.1 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 CCC71642.1 - 8.3e-05 21.4 0.0 0.00012 20.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 CCC71642.1 - 0.0034 17.6 0.2 0.056 13.7 0.0 2.6 2 1 1 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 CCC71642.1 - 0.0093 14.9 0.0 0.02 13.8 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase ParBc PF02195.13 CCC71643.1 - 7.8e-11 41.9 0.0 9.5e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain Cyto_heme_lyase PF01265.12 CCC71644.1 - 9.8e-69 231.8 15.7 1.9e-67 227.5 10.9 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Flavoprotein PF02441.14 CCC71645.1 - 1.3e-40 138.0 1.6 2.3e-40 137.2 0.1 2.2 2 0 0 2 2 2 1 Flavoprotein FTR_C PF02741.10 CCC71645.1 - 1 9.1 3.8 1.1 9.0 0.1 2.2 2 0 0 2 2 2 0 FTR, proximal lobe Peptidase_S24 PF00717.18 CCC71646.1 - 4.7e-09 35.7 0.0 8e-09 35.0 0.0 1.4 1 1 0 1 1 1 1 Peptidase S24-like Ydc2-catalyt PF09159.5 CCC71647.1 - 1.6e-51 175.3 0.6 2.3e-51 174.8 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 Pox_A22 PF04848.8 CCC71647.1 - 0.0039 17.0 0.5 0.44 10.3 0.0 3.2 2 2 0 2 2 2 1 Poxvirus A22 protein DUF4261 PF14080.1 CCC71647.1 - 0.024 14.4 0.0 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4261) DEAD PF00270.24 CCC71649.1 - 0.0088 15.5 0.0 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF3638 PF12340.3 CCC71649.1 - 0.042 12.8 0.0 0.055 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) MIP PF00230.15 CCC71650.1 - 7e-37 127.0 14.7 8e-37 126.8 10.2 1.0 1 0 0 1 1 1 1 Major intrinsic protein ARPC4 PF05856.7 CCC71651.1 - 5.4e-71 237.4 3.9 6e-71 237.3 2.7 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF3832 PF12909.2 CCC71651.1 - 0.029 14.4 0.2 0.07 13.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3832) Fungal_trans PF04082.13 CCC71652.1 - 4.2e-26 91.3 4.1 5.1e-26 91.1 1.6 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC71652.1 - 1.3e-10 40.9 7.8 2.7e-10 39.9 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mt_ATP-synt_D PF05873.7 CCC71653.1 - 1.6e-13 50.6 4.6 2e-13 50.3 3.2 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) DUF677 PF05055.7 CCC71653.1 - 0.00058 18.6 4.8 0.0011 17.7 3.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF677) EzrA PF06160.7 CCC71653.1 - 0.0053 15.0 2.4 0.0053 15.0 1.7 1.9 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA AAA_12 PF13087.1 CCC71654.1 - 9.3e-60 201.4 0.0 2.3e-59 200.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 CCC71654.1 - 6.9e-53 179.6 1.2 7.4e-53 179.5 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCC71654.1 - 4.6e-14 51.9 0.0 1.2e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 CCC71654.1 - 1.2e-10 41.3 0.0 1.3e-07 31.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 CCC71654.1 - 2.8e-07 30.2 0.3 0.2 11.1 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 CCC71654.1 - 1.3e-05 24.6 0.2 7.1e-05 22.2 0.0 2.3 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 CCC71654.1 - 4.9e-05 23.4 0.1 0.0013 18.8 0.0 2.5 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.9 CCC71654.1 - 6.2e-05 22.6 0.0 0.00069 19.2 0.0 2.5 2 0 0 2 2 2 1 Helicase DEAD PF00270.24 CCC71654.1 - 0.00019 21.0 0.2 0.0022 17.4 0.0 2.3 1 1 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 CCC71654.1 - 0.00023 21.0 0.0 0.0013 18.5 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 CCC71654.1 - 0.00026 20.2 0.0 0.0023 17.1 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Zot PF05707.7 CCC71654.1 - 0.00058 19.3 0.6 0.0015 17.9 0.0 2.1 3 0 0 3 3 2 1 Zonular occludens toxin (Zot) IstB_IS21 PF01695.12 CCC71654.1 - 0.0015 17.9 0.0 0.0036 16.7 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein PIF1 PF05970.9 CCC71654.1 - 0.0016 17.4 0.0 0.085 11.7 0.0 2.5 2 0 0 2 2 2 1 PIF1-like helicase DUF2075 PF09848.4 CCC71654.1 - 0.0029 16.6 0.2 0.016 14.2 0.0 2.2 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 CCC71654.1 - 0.0051 15.4 0.0 0.01 14.4 0.0 1.5 1 0 0 1 1 1 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.1 CCC71654.1 - 0.0066 16.4 0.0 0.034 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 CCC71654.1 - 0.0073 16.5 0.0 0.034 14.3 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF853 PF05872.7 CCC71654.1 - 0.01 14.2 0.0 0.019 13.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) AAA_14 PF13173.1 CCC71654.1 - 0.013 15.3 0.3 0.17 11.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF258 PF03193.11 CCC71654.1 - 0.018 14.2 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 CCC71654.1 - 0.018 14.4 0.0 0.047 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain UvrD_C_2 PF13538.1 CCC71654.1 - 0.019 15.1 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_10 PF12846.2 CCC71654.1 - 0.021 14.2 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain T2SE PF00437.15 CCC71654.1 - 0.025 13.5 0.1 0.045 12.6 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_17 PF13207.1 CCC71654.1 - 0.12 13.2 1.9 0.44 11.3 0.6 2.6 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CCC71654.1 - 0.13 11.6 0.0 0.4 10.1 0.0 1.8 1 0 0 1 1 1 0 FtsK/SpoIIIE family WD40 PF00400.27 CCC71655.1 - 1.3e-14 53.4 0.5 4.1e-05 23.2 0.0 5.6 6 0 0 6 6 6 3 WD domain, G-beta repeat Lactonase PF10282.4 CCC71655.1 - 0.011 14.8 0.0 0.082 11.9 0.0 2.3 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller DUF1748 PF08520.5 CCC71656.1 - 3.6e-16 58.5 0.2 4.6e-16 58.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) PPTA PF01239.17 CCC71657.1 - 4.9e-41 136.3 16.2 6.2e-08 31.6 0.2 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat DnaJ PF00226.26 CCC71658.1 - 3.8e-15 55.3 1.2 1.3e-14 53.6 0.8 2.0 1 0 0 1 1 1 1 DnaJ domain Acyl-CoA_ox_N PF14749.1 CCC71658.1 - 0.26 11.5 3.2 0.5 10.6 2.1 1.6 1 1 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal ORC5_C PF14630.1 CCC71659.1 - 7.8e-65 219.0 0.9 1.3e-64 218.3 0.7 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 CCC71659.1 - 2.2e-05 24.5 0.0 5.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 CCC71659.1 - 2.3e-05 24.5 0.0 5.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain zf-CCHC PF00098.18 CCC71660.1 - 5.1e-05 22.9 3.1 8.4e-05 22.3 2.1 1.4 1 0 0 1 1 1 1 Zinc knuckle AbiH PF14253.1 CCC71660.1 - 0.0012 18.5 3.2 0.042 13.4 0.4 2.1 2 0 0 2 2 2 2 Bacteriophage abortive infection AbiH TBPIP PF07106.8 CCC71660.1 - 0.0061 16.1 4.1 0.0065 16.0 0.2 2.4 2 1 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) zf-CCHC_4 PF14392.1 CCC71660.1 - 0.021 14.4 1.1 0.039 13.6 0.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1664 PF07889.7 CCC71660.1 - 1.5 8.5 4.6 0.92 9.3 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.2 CCC71660.1 - 2.3 8.0 8.9 0.13 12.1 0.9 2.5 2 1 1 3 3 3 0 Tropomyosin like RVT_1 PF00078.22 CCC71661.1 - 7.2e-23 81.0 0.5 7.2e-23 81.0 0.4 1.9 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 CCC71661.1 - 4.3e-19 68.7 0.0 1.5e-18 67.0 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag-asp_proteas PF13975.1 CCC71661.1 - 8.5e-06 25.4 0.0 2.1e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Peptidase_A2B PF12384.3 CCC71661.1 - 0.0001 21.6 0.1 0.00032 20.0 0.1 1.8 1 0 0 1 1 1 1 Ty3 transposon peptidase Asp_protease_2 PF13650.1 CCC71661.1 - 0.00012 22.4 0.0 0.00067 20.1 0.0 2.4 2 0 0 2 2 2 1 Aspartyl protease zf-H2C2 PF09337.5 CCC71661.1 - 0.0022 17.3 0.1 0.0058 16.0 0.1 1.7 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger RVP PF00077.15 CCC71661.1 - 0.003 17.4 0.0 0.0098 15.7 0.0 1.9 1 0 0 1 1 1 1 Retroviral aspartyl protease WD40 PF00400.27 CCC71663.1 - 4.4e-30 102.4 3.2 1e-07 31.5 0.1 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 CCC71663.1 - 0.0028 15.8 0.5 0.015 13.4 0.1 2.1 2 1 1 3 3 3 1 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 CCC71663.1 - 0.0044 16.7 0.5 4 7.2 0.0 3.8 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 CCC71663.1 - 0.012 14.4 1.5 6.6 5.3 0.4 3.3 2 1 1 3 3 3 0 Nup133 N terminal like TPR_1 PF00515.23 CCC71664.1 - 7.2e-35 117.1 22.0 4.9e-06 25.9 0.1 9.9 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 CCC71664.1 - 1.1e-33 112.3 23.1 6.2e-05 22.6 0.1 10.3 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_11 PF13414.1 CCC71664.1 - 1.9e-27 94.7 25.7 6e-10 38.6 0.2 7.5 5 2 3 8 8 8 8 TPR repeat Apc3 PF12895.2 CCC71664.1 - 5.4e-25 87.3 21.8 6.6e-21 74.2 0.2 5.5 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 CCC71664.1 - 1.2e-21 76.7 1.4 3e-08 34.1 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 CCC71664.1 - 6.3e-21 74.0 22.2 7.1e-08 32.2 0.7 8.9 6 3 2 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 CCC71664.1 - 1.6e-19 68.1 23.9 0.00026 20.5 0.1 10.1 11 1 1 12 12 11 4 Tetratricopeptide repeat TPR_14 PF13428.1 CCC71664.1 - 3e-19 67.7 0.9 0.00035 20.9 0.0 8.9 7 2 2 10 10 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 CCC71664.1 - 3.8e-18 65.5 6.2 4.7e-07 30.0 0.1 6.7 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.1 CCC71664.1 - 1.5e-15 55.6 10.8 1.9e-05 24.0 0.1 8.6 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 CCC71664.1 - 5.4e-13 48.0 6.1 0.48 10.7 0.0 9.6 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_10 PF13374.1 CCC71664.1 - 8.1e-11 41.4 2.7 0.12 12.3 0.0 7.1 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 CCC71664.1 - 8.9e-08 32.1 15.4 0.42 11.1 0.0 7.9 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 CCC71664.1 - 1.4e-05 24.8 0.2 0.0024 17.6 0.1 3.9 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 CCC71664.1 - 1.4e-05 24.2 5.4 0.0095 15.0 0.5 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCC71664.1 - 3.1e-05 23.7 9.4 2.2 8.2 0.0 4.9 4 0 0 4 4 4 3 Fis1 C-terminal tetratricopeptide repeat TPR_21 PF09976.4 CCC71664.1 - 0.0015 18.4 0.2 10 6.0 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Hs1pro-1_N PF07231.7 CCC71664.1 - 0.0028 17.2 0.2 0.0067 16.0 0.1 1.6 1 0 0 1 1 1 1 Hs1pro-1 N-terminus TPR_4 PF07721.9 CCC71664.1 - 0.058 13.8 0.2 1.7e+02 3.1 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat ADK PF00406.17 CCC71666.1 - 5.7e-48 162.6 0.0 8.1e-48 162.1 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 CCC71666.1 - 4.7e-09 36.6 0.0 8.3e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 CCC71666.1 - 2e-07 30.9 0.0 7.4e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 CCC71666.1 - 1.4e-06 29.1 0.0 2.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 CCC71666.1 - 1.3e-05 24.6 0.3 0.14 11.5 0.0 2.2 1 1 1 2 2 2 2 Thymidylate kinase SRP54 PF00448.17 CCC71666.1 - 0.028 13.8 0.0 0.13 11.6 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 CCC71666.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 CCC71666.1 - 0.15 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain adh_short PF00106.20 CCC71667.1 - 2.5e-31 108.8 0.0 3.3e-31 108.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 CCC71667.1 - 2e-13 50.6 0.2 2.4e-13 50.3 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 CCC71667.1 - 2.1e-12 47.0 0.0 2.8e-12 46.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 CCC71667.1 - 1.7e-06 27.6 0.1 2.5e-06 27.1 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 CCC71667.1 - 0.019 14.9 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding TrkA_N PF02254.13 CCC71667.1 - 0.05 13.5 0.1 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain G6PD_C PF02781.11 CCC71669.1 - 1.2e-103 346.0 0.0 1.5e-103 345.7 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 CCC71669.1 - 1.2e-54 185.3 0.0 1.7e-54 184.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Sugar_tr PF00083.19 CCC71670.1 - 8.7e-157 522.2 25.6 1e-156 522.0 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC71670.1 - 2.4e-27 95.6 35.5 2.3e-21 75.9 9.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCC71670.1 - 0.038 12.0 4.9 0.034 12.2 1.1 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector GSHPx PF00255.14 CCC71671.1 - 3.1e-46 155.1 1.1 4e-46 154.8 0.8 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 CCC71671.1 - 0.00091 18.9 0.3 0.0034 17.0 0.2 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 CCC71671.1 - 0.016 14.7 0.5 0.11 12.0 0.3 2.0 1 1 0 1 1 1 0 Redoxin DUF4174 PF13778.1 CCC71671.1 - 0.018 15.1 0.1 0.031 14.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) PLA2_B PF01735.13 CCC71672.1 - 1e-211 703.3 2.4 1.6e-211 702.7 1.7 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain SOR_SNZ PF01680.12 CCC71673.1 - 2e-109 364.0 2.7 2.8e-109 363.5 1.9 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 CCC71673.1 - 1.4e-09 37.4 0.8 1.1e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG TMP-TENI PF02581.12 CCC71673.1 - 0.0028 16.8 0.2 0.13 11.3 0.0 2.6 2 1 1 3 3 3 1 Thiamine monophosphate synthase/TENI IGPS PF00218.16 CCC71673.1 - 0.016 14.3 0.1 0.12 11.3 0.0 2.2 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase NanE PF04131.9 CCC71673.1 - 0.019 13.9 0.7 0.21 10.5 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 CCC71673.1 - 0.022 14.0 0.0 0.3 10.3 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein Dus PF01207.12 CCC71673.1 - 0.031 13.1 0.2 7 5.3 0.0 2.8 2 1 1 3 3 3 0 Dihydrouridine synthase (Dus) Myosin_tail_1 PF01576.14 CCC71673.1 - 0.058 11.1 0.1 0.078 10.6 0.1 1.0 1 0 0 1 1 1 0 Myosin tail NMO PF03060.10 CCC71673.1 - 0.096 11.8 3.6 0.12 11.4 0.1 2.3 2 2 0 2 2 2 0 Nitronate monooxygenase PEP_mutase PF13714.1 CCC71673.1 - 0.1 11.8 0.8 0.92 8.6 0.1 2.5 2 1 0 2 2 2 0 Phosphoenolpyruvate phosphomutase SNO PF01174.14 CCC71674.1 - 5.7e-77 257.5 0.0 6.6e-77 257.4 0.0 1.0 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 CCC71674.1 - 2.6e-06 27.1 0.0 4.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain DUF4066 PF13278.1 CCC71674.1 - 0.1 11.8 0.0 0.28 10.4 0.0 1.7 2 0 0 2 2 2 0 Putative amidotransferase DEAD PF00270.24 CCC71676.1 - 2.6e-11 43.3 0.0 5.9e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC71677.1 - 1.4e-06 28.0 0.0 2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TRI12 PF06609.8 CCC71679.1 - 2e-06 26.2 16.3 4.4e-06 25.1 11.2 1.5 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 CCC71679.1 - 5.6e-05 22.0 35.0 0.00077 18.2 24.2 3.0 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 CCC71679.1 - 0.00091 17.9 11.7 0.00091 17.9 8.1 2.3 2 1 1 3 3 3 1 Sugar (and other) transporter Hph PF13694.1 CCC71680.1 - 1.4e-09 38.2 10.5 1.4e-09 38.2 7.3 3.5 2 1 1 3 3 3 1 Sec63/Sec62 complex-interacting family Prefoldin_2 PF01920.15 CCC71680.1 - 0.3 10.8 11.7 0.03 14.0 4.6 2.0 2 0 0 2 2 2 0 Prefoldin subunit Fib_alpha PF08702.5 CCC71680.1 - 0.36 10.9 11.0 0.029 14.4 3.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Myosin_head PF00063.16 CCC71681.1 - 1.7e-261 869.2 8.6 1.7e-261 869.2 5.9 1.6 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 CCC71681.1 - 2.4e-33 114.1 0.8 2.4e-33 114.1 0.6 2.8 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 CCC71681.1 - 1.5e-08 33.4 17.4 0.093 12.4 0.5 5.7 5 0 0 5 5 5 4 IQ calmodulin-binding motif AAA_22 PF13401.1 CCC71681.1 - 0.0022 18.1 1.8 0.012 15.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain Myosin_N PF02736.14 CCC71681.1 - 0.015 14.9 0.3 0.057 13.1 0.1 2.3 2 0 0 2 2 2 0 Myosin N-terminal SH3-like domain AAA_19 PF13245.1 CCC71681.1 - 0.1 12.3 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain FlaC_arch PF05377.6 CCC71681.1 - 4.8 7.1 13.7 2 8.3 1.3 3.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Synaptobrevin PF00957.16 CCC71682.1 - 8.4e-32 108.6 1.3 9.5e-32 108.4 0.9 1.0 1 0 0 1 1 1 1 Synaptobrevin Rifin_STEVOR PF02009.11 CCC71682.1 - 0.078 12.6 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family Phage_rep_O PF04492.8 CCC71682.1 - 0.079 13.1 0.0 0.13 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage replication protein O ODV-E18 PF10717.4 CCC71682.1 - 0.12 11.8 0.2 0.21 11.0 0.2 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF3168 PF11367.3 CCC71683.1 - 0.08 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3168) bZIP_1 PF00170.16 CCC71684.1 - 3.2e-13 49.4 12.1 5.4e-13 48.6 8.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 CCC71684.1 - 1.2e-11 44.2 10.9 2.1e-11 43.4 7.6 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 CCC71684.1 - 0.0044 17.2 4.0 0.0084 16.3 2.7 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor AKAP2_C PF15304.1 CCC71684.1 - 0.0089 15.6 0.5 0.0089 15.6 0.3 1.5 2 0 0 2 2 2 1 A-kinase anchor protein 2 C-terminus Glyco_transf_25 PF01755.12 CCC71684.1 - 0.025 14.2 0.1 0.046 13.3 0.1 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 25 (LPS biosynthesis protein) DivIC PF04977.10 CCC71684.1 - 0.4 10.1 3.4 0.65 9.5 1.9 1.6 1 1 0 1 1 1 0 Septum formation initiator DUF972 PF06156.8 CCC71684.1 - 0.53 10.6 4.3 1.1 9.6 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Urm1 PF09138.6 CCC71685.1 - 1.3e-34 118.1 0.5 1.6e-34 117.8 0.4 1.1 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 CCC71685.1 - 0.022 15.1 0.1 0.031 14.7 0.1 1.3 1 0 0 1 1 1 0 ThiS family ApoLp-III PF07464.6 CCC71686.1 - 0.055 13.5 7.2 1.2 9.1 0.6 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Apolipoprotein PF01442.13 CCC71686.1 - 0.12 11.9 6.0 1.5 8.2 4.2 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Rsc14 PF08586.5 CCC71686.1 - 0.25 11.8 2.1 0.54 10.7 1.3 1.9 1 1 0 1 1 1 0 RSC complex, Rsc14/Ldb7 subunit OmpH PF03938.9 CCC71686.1 - 0.71 9.8 13.0 0.054 13.4 5.0 2.1 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) AKNA PF12443.3 CCC71686.1 - 2.6 8.0 9.4 11 6.1 0.0 3.9 1 1 3 4 4 4 0 AT-hook-containing transcription factor AAA_22 PF13401.1 CCC71686.1 - 4.3 7.4 5.9 0.97 9.5 1.3 1.9 1 1 1 2 2 2 0 AAA domain DUF262 PF03235.9 CCC71686.1 - 4.7 7.1 15.3 13 5.7 10.6 1.8 1 1 0 1 1 1 0 Protein of unknown function DUF262 COPIIcoated_ERV PF07970.7 CCC71687.1 - 1.6e-69 233.9 0.0 2e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCC71687.1 - 1.2e-31 108.5 0.3 2.5e-31 107.4 0.2 1.5 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PX PF00787.19 CCC71688.1 - 5.7e-21 74.4 1.3 1.4e-20 73.1 0.5 1.8 1 1 1 2 2 2 1 PX domain CBFD_NFYB_HMF PF00808.18 CCC71689.1 - 1.3e-19 69.9 1.0 2.3e-19 69.1 0.7 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 CCC71689.1 - 6e-16 58.3 0.2 9.3e-16 57.7 0.1 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 SAM_2 PF07647.12 CCC71690.1 - 4.6e-08 32.7 2.3 2.6e-07 30.4 0.1 2.6 2 1 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 CCC71690.1 - 8.3e-06 25.8 0.1 2e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 CCC71690.1 - 0.12 12.3 0.2 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 IGR protein motif PDEase_I PF00233.14 CCC71691.1 - 1.1e-49 169.2 0.9 2.7e-49 168.0 0.4 1.8 1 1 1 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.17 CCC71691.1 - 0.0093 15.9 0.0 0.023 14.6 0.0 1.7 1 0 0 1 1 1 1 HD domain eIF2A PF08662.6 CCC71692.1 - 2.7e-28 99.0 2.4 1.2e-25 90.4 0.4 3.4 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 CCC71692.1 - 3.6e-09 36.1 0.1 1e-08 34.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC71692.1 - 5.4e-07 29.4 0.2 2e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC71692.1 - 0.0016 18.2 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 CCC71692.1 - 0.065 13.1 1.4 17 5.4 0.1 4.6 4 0 0 4 4 4 0 WD domain, G-beta repeat Proteasome PF00227.21 CCC71693.1 - 5.3e-49 166.0 0.0 6.9e-49 165.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 CCC71693.1 - 1e-11 43.9 0.0 1e-11 43.9 0.0 2.3 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature DLH PF01738.13 CCC71694.1 - 3.7e-36 124.4 0.0 4.2e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 CCC71694.1 - 4.1e-09 36.3 0.0 5.1e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 CCC71694.1 - 0.0044 16.9 0.0 0.15 11.9 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.6 CCC71694.1 - 0.069 12.8 0.1 0.28 10.8 0.0 1.8 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 CCC71694.1 - 0.07 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 CCC71694.1 - 0.079 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Zn_clus PF00172.13 CCC71695.1 - 1.5e-10 40.7 9.5 2.6e-10 40.0 6.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUP PF00674.13 CCC71696.1 - 2.3e-12 46.8 4.5 2.7e-12 46.5 2.5 1.6 1 1 1 2 2 2 1 DUP family DUF4131 PF13567.1 CCC71696.1 - 0.017 14.5 0.4 0.025 14.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Tetraspannin PF00335.15 CCC71696.1 - 0.034 13.4 1.4 0.046 12.9 1.0 1.3 1 0 0 1 1 1 0 Tetraspanin family DUF962 PF06127.6 CCC71696.1 - 0.062 13.2 2.4 0.097 12.5 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF962) SdpI PF13630.1 CCC71696.1 - 3.1 7.5 6.2 1.5 8.6 2.6 1.6 2 0 0 2 2 2 0 SdpI/YhfL protein family CH PF00307.26 CCC71697.1 - 1.3e-11 44.4 0.0 1.8e-11 44.0 0.0 1.2 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 CCC71697.1 - 0.052 13.6 0.0 0.089 12.8 0.0 1.4 1 0 0 1 1 1 0 CDC24 Calponin Peroxin-22 PF12827.2 CCC71698.1 - 8.6e-28 96.3 0.3 1.1e-27 96.0 0.2 1.2 1 0 0 1 1 1 1 Peroxisomal biogenesis protein family SpoIIIAH PF12685.2 CCC71698.1 - 0.00099 18.6 0.3 0.0012 18.3 0.2 1.2 1 0 0 1 1 1 1 SpoIIIAH-like protein DUF2665 PF11654.3 CCC71698.1 - 0.0072 15.8 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) DUF4199 PF13858.1 CCC71698.1 - 0.065 13.1 0.0 0.09 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Rad1 PF02144.11 CCC71699.1 - 4.3e-68 229.0 2.0 4.3e-68 229.0 1.4 1.5 2 0 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 Ribosomal_L7Ae PF01248.21 CCC71700.1 - 2.7e-23 81.2 0.1 3.5e-23 80.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1269 PF06897.7 CCC71700.1 - 0.0065 16.4 1.4 0.026 14.5 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1269) SapB_1 PF05184.10 CCC71700.1 - 1.6 8.6 4.9 5.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 GDI PF00996.13 CCC71701.1 - 1.7e-54 184.7 0.1 2.3e-54 184.3 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor DUF3295 PF11702.3 CCC71701.1 - 8.5 5.2 5.6 13 4.6 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Kelch_6 PF13964.1 CCC71702.1 - 9e-09 35.1 4.1 0.034 14.3 0.0 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_3 PF13415.1 CCC71702.1 - 5.8e-07 29.5 1.5 0.072 13.2 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_4 PF13418.1 CCC71702.1 - 2.1e-06 27.4 6.1 0.0051 16.5 0.0 4.6 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.1 CCC71702.1 - 0.00012 21.9 6.2 1.6 8.7 0.0 5.7 6 0 0 6 6 6 1 Kelch motif Kelch_2 PF07646.10 CCC71702.1 - 0.026 14.3 4.9 2.4 8.0 0.2 4.8 6 0 0 6 6 6 0 Kelch motif Kelch_1 PF01344.20 CCC71702.1 - 0.03 13.8 8.7 1.2 8.6 0.0 4.6 6 0 0 6 6 6 0 Kelch motif LRR_4 PF12799.2 CCC71704.1 - 3.4e-14 52.0 60.5 1.8e-08 33.7 3.2 8.4 4 3 3 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 CCC71704.1 - 1.1e-07 31.4 51.8 0.00016 21.3 1.0 6.8 4 2 2 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 CCC71704.1 - 2.8e-05 23.5 46.8 0.24 11.5 0.1 11.1 10 1 1 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.1 CCC71704.1 - 0.3 11.2 46.7 0.18 11.9 0.8 10.2 11 0 0 11 11 11 0 Leucine Rich repeat LRR_7 PF13504.1 CCC71704.1 - 0.78 10.2 42.7 8.1 7.1 0.1 11.2 12 0 0 12 12 12 0 Leucine rich repeat LRR_9 PF14580.1 CCC71704.1 - 2.2 7.8 12.5 4.2 6.8 0.5 4.1 2 1 3 5 5 5 0 Leucine-rich repeat Aldedh PF00171.17 CCC71705.1 - 1e-182 607.6 0.4 1.3e-182 607.3 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 CCC71705.1 - 0.00045 19.0 0.1 0.0019 17.0 0.1 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 CCC71705.1 - 0.00091 18.5 0.1 0.49 9.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) RSF PF14876.1 CCC71706.1 - 1.3e-05 24.1 0.4 1.3e-05 24.1 0.3 2.5 3 0 0 3 3 3 1 Respiratory growth transcriptional regulator SRI PF08236.6 CCC71706.1 - 0.03 14.2 0.2 0.083 12.8 0.0 1.8 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Aldedh PF00171.17 CCC71707.1 - 2.3e-14 52.6 0.1 4.9e-10 38.3 0.0 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Ribosomal_L28e PF01778.12 CCC71708.1 - 3.6e-34 117.6 0.5 3.6e-34 117.6 0.3 2.0 3 0 0 3 3 3 1 Ribosomal L28e protein family Mak16 PF04874.9 CCC71708.1 - 4e-34 116.7 17.8 4e-34 116.7 12.3 2.8 2 1 0 2 2 2 1 Mak16 protein C-terminal region CENP-T PF15511.1 CCC71708.1 - 0.15 11.2 13.5 0.2 10.8 9.3 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T PYC_OADA PF02436.13 CCC71708.1 - 0.18 11.2 1.5 0.43 9.9 1.1 1.8 1 1 0 1 1 1 0 Conserved carboxylase domain Nop14 PF04147.7 CCC71708.1 - 0.51 8.1 33.1 0.69 7.7 23.0 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 CCC71708.1 - 5 5.3 32.3 6.1 5.0 22.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) LDB19 PF13002.2 CCC71709.1 - 4.4e-89 297.0 0.7 6.8e-89 296.4 0.5 1.3 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 CCC71709.1 - 7.7e-05 22.5 0.9 0.00037 20.3 0.1 2.5 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain PMT PF02366.13 CCC71710.1 - 2.8e-84 282.3 20.0 2.8e-84 282.3 13.8 2.4 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCC71710.1 - 7.5e-24 84.3 2.7 1.8e-23 83.0 1.8 1.7 1 1 0 1 1 1 1 MIR domain Med15_fungi PF05397.7 CCC71711.1 - 4.1e-20 71.8 0.6 2e-19 69.6 0.4 2.3 1 0 0 1 1 1 1 Mediator complex subunit 15 GSH_synth_ATP PF03917.12 CCC71712.1 - 3e-104 348.5 0.0 3.5e-104 348.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 CCC71712.1 - 2.7e-34 117.3 0.0 5e-34 116.5 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase EI24 PF07264.6 CCC71714.1 - 6.6e-09 35.5 3.7 6.6e-09 35.5 2.6 2.1 2 0 0 2 2 2 2 Etoposide-induced protein 2.4 (EI24) Pkinase PF00069.20 CCC71715.1 - 1.4e-62 211.1 1.1 7e-62 208.9 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71715.1 - 2.6e-23 82.3 0.0 4.4e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC71715.1 - 2.3e-09 36.6 0.0 4.4e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 CCC71715.1 - 0.012 14.7 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC71715.1 - 0.02 14.6 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAS PF00989.19 CCC71715.1 - 0.062 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 PAS fold Mannosyl_trans3 PF11051.3 CCC71716.1 - 2.5e-60 204.1 1.0 3.4e-60 203.7 0.7 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative P21-Arc PF04062.9 CCC71717.1 - 0.096 12.4 0.5 1.7 8.4 0.0 2.6 2 1 0 2 2 2 0 ARP2/3 complex ARPC3 (21 kDa) subunit Exo_endo_phos PF03372.18 CCC71718.1 - 5.8e-16 59.1 0.0 7.7e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_60s PF00428.14 CCC71721.1 - 3.2e-23 81.9 17.0 3.7e-23 81.7 11.8 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Joubert PF15392.1 CCC71721.1 - 0.056 12.6 0.1 0.07 12.3 0.0 1.1 1 0 0 1 1 1 0 Joubert syndrome-associated DUF775 PF05603.7 CCC71723.1 - 3.2e-59 199.8 0.1 3.7e-59 199.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) Latrotoxin_C PF15658.1 CCC71723.1 - 0.12 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Latrotoxin C-terminal domain tRNA-synt_1c PF00749.16 CCC71724.1 - 8.9e-110 366.2 0.0 1.2e-109 365.7 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain TUG-UBL1 PF11470.3 CCC71724.1 - 0.0042 16.9 0.0 0.013 15.4 0.0 1.8 1 0 0 1 1 1 1 GLUT4 regulating protein TUG SMC_N PF02463.14 CCC71725.1 - 2.2e-17 63.0 28.8 6e-17 61.6 19.9 1.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCC71725.1 - 1.1e-14 55.2 24.4 1.1e-14 55.2 16.9 5.3 2 2 1 3 3 1 1 AAA domain AAA_29 PF13555.1 CCC71725.1 - 2.1e-05 23.9 0.0 4.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 CCC71725.1 - 4e-05 23.7 7.5 4e-05 23.7 5.2 3.9 2 2 1 3 3 3 1 AAA domain AAA_25 PF13481.1 CCC71725.1 - 0.0022 17.4 0.0 0.0096 15.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain MutS_V PF00488.16 CCC71725.1 - 0.028 13.8 0.0 0.11 11.9 0.0 1.9 2 0 0 2 2 2 0 MutS domain V AAA_33 PF13671.1 CCC71725.1 - 0.049 13.5 0.5 0.58 10.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 CCC71725.1 - 0.057 12.8 2.2 0.63 9.4 0.0 2.7 2 1 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 CCC71725.1 - 0.16 12.2 0.0 0.16 12.2 0.0 5.5 4 2 0 4 4 3 0 ABC transporter Baculo_PEP_C PF04513.7 CCC71725.1 - 0.46 10.3 30.1 0.16 11.8 0.5 5.8 4 3 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FUSC PF04632.7 CCC71725.1 - 1.2 7.4 2.3 0.81 8.0 0.0 1.8 3 0 0 3 3 3 0 Fusaric acid resistance protein family Reo_sigmaC PF04582.7 CCC71725.1 - 1.3 8.1 20.1 0.55 9.3 1.2 4.2 4 0 0 4 4 4 0 Reovirus sigma C capsid protein COOH-NH2_lig PF14395.1 CCC71725.1 - 2.1 7.3 7.8 0.19 10.7 0.4 2.7 3 0 0 3 3 3 0 Phage phiEco32-like COOH.NH2 ligase-type 2 B56 PF01603.15 CCC71727.1 - 3.6e-147 490.2 18.7 1.5e-138 461.8 10.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) DUF2120 PF09893.4 CCC71727.1 - 0.093 12.6 3.2 0.12 12.2 1.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) EMP24_GP25L PF01105.19 CCC71728.1 - 4.4e-30 104.7 0.0 5.2e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Pet127 PF08634.5 CCC71729.1 - 1.5e-107 358.8 7.5 9.6e-106 352.9 5.2 2.3 1 1 0 1 1 1 1 Mitochondrial protein Pet127 DUF1021 PF06257.6 CCC71729.1 - 0.091 12.4 0.5 0.32 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1021) Glyco_hydro_72 PF03198.9 CCC71730.1 - 3.4e-145 482.9 4.6 4.4e-145 482.5 3.2 1.1 1 0 0 1 1 1 1 Glucanosyltransferase Glyco_hydro_2_C PF02836.12 CCC71730.1 - 0.00012 21.1 0.1 0.00028 19.9 0.1 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase PF00150.13 CCC71730.1 - 0.0015 17.8 0.1 0.0088 15.2 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Sporozoite_P67 PF05642.6 CCC71730.1 - 1.6 6.4 16.8 2.2 6.0 11.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Golgin_A5 PF09787.4 CCC71730.1 - 3.8 5.9 15.2 9 4.6 10.6 1.5 2 0 0 2 2 2 0 Golgin subfamily A member 5 Apt1 PF10351.4 CCC71730.1 - 4 6.1 14.4 6.2 5.5 10.0 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Tmemb_cc2 PF10267.4 CCC71730.1 - 4.5 5.7 8.7 6.3 5.2 6.1 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein bZIP_1 PF00170.16 CCC71731.1 - 4.2e-05 23.4 12.0 4.2e-05 23.4 8.3 2.0 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 CCC71731.1 - 0.0096 15.7 9.6 0.0096 15.7 6.6 2.3 2 0 0 2 2 2 1 Basic region leucine zipper DUF3439 PF11921.3 CCC71731.1 - 0.38 10.5 13.2 1 9.1 9.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) bZIP_Maf PF03131.12 CCC71731.1 - 4.3 7.6 18.7 0.33 11.2 5.1 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor LETM1 PF07766.8 CCC71732.1 - 7.8e-100 333.3 5.2 1.1e-99 332.8 3.6 1.2 1 0 0 1 1 1 1 LETM1-like protein TOM13 PF08219.6 CCC71733.1 - 1.1e-27 95.5 0.1 1.5e-27 95.1 0.1 1.2 1 0 0 1 1 1 1 Outer membrane protein TOM13 SRP1_TIP1 PF00660.12 CCC71734.1 - 3.9e-36 123.0 0.7 1.1e-35 121.5 0.5 1.8 1 0 0 1 1 1 1 Seripauperin and TIP1 family Macoilin PF09726.4 CCC71734.1 - 1.2 7.2 16.1 1.6 6.9 11.2 1.1 1 0 0 1 1 1 0 Transmembrane protein TFIIA PF03153.8 CCC71734.1 - 1.3 8.8 10.2 1.7 8.4 7.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit KAR9 PF08580.5 CCC71734.1 - 2.3 6.3 9.8 2.8 6.0 6.8 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 CytochromB561_N PF09786.4 CCC71734.1 - 2.9 6.2 14.2 4 5.7 9.8 1.3 1 1 0 1 1 1 0 Cytochrome B561, N terminal ABC2_membrane PF01061.19 CCC71735.1 - 3.1e-68 229.0 60.5 1.9e-35 121.9 11.1 3.1 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 CCC71735.1 - 5.1e-30 103.1 11.7 5.7e-26 90.1 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 CCC71735.1 - 1.8e-29 102.8 0.1 1.8e-16 60.7 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 CCC71735.1 - 2.9e-13 49.5 35.6 1.9e-09 37.0 6.4 3.7 2 2 1 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.1 CCC71735.1 - 9.3e-05 22.5 1.1 9.3e-05 22.5 0.8 5.1 4 2 1 5 5 5 1 AAA domain DUF258 PF03193.11 CCC71735.1 - 9.5e-05 21.6 2.0 0.00013 21.1 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SMC_N PF02463.14 CCC71735.1 - 0.00039 19.7 0.0 0.0041 16.3 0.0 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 CCC71735.1 - 0.00088 19.4 0.0 0.0027 17.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 CCC71735.1 - 0.0048 16.8 0.1 0.01 15.8 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 CCC71735.1 - 0.012 15.9 0.0 0.044 14.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 CCC71735.1 - 0.014 14.8 1.3 0.031 13.7 0.4 1.9 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 CCC71735.1 - 0.017 14.5 0.0 0.041 13.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 CCC71735.1 - 0.02 15.2 2.0 0.032 14.5 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 CCC71735.1 - 0.042 13.5 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 CCC71735.1 - 0.044 13.4 1.1 0.08 12.5 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 CCC71735.1 - 0.075 12.5 0.6 0.18 11.3 0.4 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 CCC71735.1 - 0.082 13.7 0.0 0.26 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 CCC71735.1 - 0.61 9.6 0.1 1.1 8.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP1_TIP1 PF00660.12 CCC71737.1 - 2.6e-25 88.2 0.1 7.4e-25 86.7 0.1 1.7 1 0 0 1 1 1 1 Seripauperin and TIP1 family PIR PF00399.14 CCC71737.1 - 0.00028 20.1 8.5 0.00028 20.1 5.9 2.9 2 0 0 2 2 2 1 Yeast PIR protein repeat SOG2 PF10428.4 CCC71737.1 - 0.015 14.0 8.2 0.016 13.8 5.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pol_alpha_B_N PF08418.5 CCC71737.1 - 1.9 7.9 8.1 2.3 7.6 5.6 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DNA_pol_viral_N PF00242.12 CCC71737.1 - 2.5 7.0 7.6 2.8 6.8 5.2 1.0 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF2217 PF10265.4 CCC71737.1 - 2.7 6.6 8.1 3 6.5 5.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Macoilin PF09726.4 CCC71737.1 - 6.1 4.9 14.6 7.1 4.7 10.1 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF3684 PF12449.3 CCC71737.1 - 7.4 4.0 8.4 8.7 3.7 5.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3684) EF-hand_4 PF12763.2 CCC71738.1 - 4e-29 100.4 0.0 6.6e-15 54.7 0.0 2.8 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 CCC71738.1 - 2.5e-08 33.9 0.0 0.0029 17.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 CCC71738.1 - 1.3e-06 27.2 0.0 0.016 14.4 0.0 3.5 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 CCC71738.1 - 2.2e-05 23.9 0.1 2 8.5 0.0 4.8 4 0 0 4 4 4 1 EF-hand domain DSBA PF01323.15 CCC71738.1 - 0.0017 17.9 0.0 0.9 9.0 0.0 2.8 2 0 0 2 2 2 2 DSBA-like thioredoxin domain Methyltransf_6 PF03737.10 CCC71739.1 - 7.3e-29 100.6 0.1 9.4e-29 100.2 0.1 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase NTF2 PF02136.15 CCC71740.1 - 8.1e-35 119.7 0.3 9.1e-35 119.5 0.2 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 CCC71740.1 - 0.0075 15.3 0.1 0.01 14.8 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4518) Sec3_C PF09763.4 CCC71741.1 - 9e-154 513.2 32.1 9e-154 513.2 22.2 2.4 3 0 0 3 3 3 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 CCC71741.1 - 1.1e-29 102.0 1.0 4.4e-29 100.1 0.7 2.1 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH PUA PF01472.15 CCC71742.1 - 5e-22 77.4 0.1 7.2e-22 76.9 0.0 1.2 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.5 CCC71742.1 - 0.0073 16.0 0.1 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1947) GN3L_Grn1 PF08701.6 CCC71743.1 - 1.7e-23 82.3 7.8 1.7e-23 82.3 5.4 2.3 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 CCC71743.1 - 1.3e-21 76.7 0.2 1e-15 57.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 CCC71743.1 - 8.5e-09 34.8 0.1 2.2e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 CCC71743.1 - 5.9e-07 29.4 0.1 0.28 11.0 0.0 3.7 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 CCC71743.1 - 9.3e-05 21.9 0.1 0.087 12.2 0.0 2.7 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.11 CCC71743.1 - 0.00016 20.8 0.0 0.00094 18.3 0.0 2.0 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 CCC71743.1 - 0.00055 19.1 0.1 0.001 18.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 CCC71743.1 - 0.02 15.3 1.6 0.58 10.6 0.0 2.7 3 0 0 3 3 2 0 Miro-like protein ArgK PF03308.11 CCC71743.1 - 0.038 12.7 0.0 0.079 11.7 0.0 1.4 1 0 0 1 1 1 0 ArgK protein cobW PF02492.14 CCC71743.1 - 0.043 13.2 0.1 2.7 7.3 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 CCC71743.1 - 0.054 13.7 0.2 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Torsin PF06309.6 CCC71743.1 - 0.14 12.0 0.1 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_16 PF13191.1 CCC71743.1 - 0.41 10.5 3.5 1.4 8.8 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain GDA1_CD39 PF01150.12 CCC71744.1 - 3.4e-138 460.8 0.0 4.5e-138 460.3 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DDOST_48kD PF03345.9 CCC71746.1 - 7e-121 403.7 8.4 8.4e-121 403.4 5.8 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF2410 PF10307.4 CCC71746.1 - 0.013 14.8 0.5 0.04 13.3 0.1 1.9 2 0 0 2 2 2 0 Hypothetical protein (DUF2410) Prefoldin_2 PF01920.15 CCC71747.1 - 1.6e-21 76.0 3.3 1.8e-21 75.8 2.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit Occludin_ELL PF07303.8 CCC71747.1 - 0.031 14.9 1.2 4.8 7.9 0.1 2.1 2 0 0 2 2 2 0 Occludin homology domain Prefoldin PF02996.12 CCC71747.1 - 0.036 13.6 3.3 0.8 9.3 2.3 2.1 1 1 0 1 1 1 0 Prefoldin subunit DUF2383 PF09537.5 CCC71747.1 - 0.079 13.2 0.2 0.18 12.0 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) MinE PF03776.9 CCC71747.1 - 0.21 11.0 2.0 0.67 9.5 0.2 2.1 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE vATP-synt_E PF01991.13 CCC71747.1 - 0.27 10.4 4.9 0.42 9.8 0.4 2.1 1 1 0 2 2 2 0 ATP synthase (E/31 kDa) subunit Tho2 PF11262.3 CCC71747.1 - 1.9 7.4 6.2 9.5 5.1 4.1 1.9 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 MucBP PF06458.7 CCC71748.1 - 0.0051 17.3 0.1 0.012 16.1 0.1 1.6 1 0 0 1 1 1 1 MucBP domain Syntaxin-6_N PF09177.6 CCC71748.1 - 0.095 13.1 1.5 3.7 8.0 0.1 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF1687 PF07955.6 CCC71748.1 - 0.29 11.1 2.8 0.54 10.2 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1687) DRIM PF07539.7 CCC71749.1 - 1.3e-49 167.2 0.3 8.8e-49 164.5 0.2 2.7 1 0 0 1 1 1 1 Down-regulated in metastasis HEAT PF02985.17 CCC71749.1 - 0.15 12.1 4.1 1.4e+02 2.9 0.0 6.3 7 0 0 7 7 7 0 HEAT repeat Rad21_Rec8_N PF04825.8 CCC71750.1 - 3.2e-27 94.6 0.6 9.9e-27 93.0 0.4 1.9 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 CCC71750.1 - 3.3e-10 39.0 0.0 6.9e-10 37.9 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 CCC71750.1 - 0.00015 21.4 0.7 0.01 15.4 0.0 2.7 2 0 0 2 2 2 2 ScpA/B protein ATP-synt_DE_N PF02823.11 CCC71751.1 - 1.5e-18 66.2 0.0 2.2e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUP PF00674.13 CCC71752.1 - 2.1e-16 59.8 0.1 4.1e-16 58.8 0.0 1.5 1 1 0 1 1 1 1 DUP family ABC2_membrane_2 PF12679.2 CCC71752.1 - 0.01 14.7 0.1 0.014 14.2 0.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Pho88 PF10032.4 CCC71752.1 - 0.027 13.6 1.1 0.08 12.1 0.0 1.9 2 0 0 2 2 2 0 Phosphate transport (Pho88) Rtt102p PF09510.5 CCC71752.1 - 0.081 12.9 0.5 0.15 12.0 0.4 1.4 1 0 0 1 1 1 0 Rtt102p-like transcription regulator protein AA_permease PF00324.16 CCC71753.1 - 6.7e-128 427.0 30.6 7.6e-128 426.8 21.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC71753.1 - 5.3e-25 87.8 34.7 6.9e-25 87.4 24.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 CCC71753.1 - 0.017 14.8 12.0 0.035 13.8 0.1 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) DUF1712 PF08217.6 CCC71754.1 - 4.3e-158 527.2 4.9 5.2e-158 527.0 3.4 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) SRP54 PF00448.17 CCC71755.1 - 1.1e-78 263.2 0.6 1.1e-78 263.2 0.4 2.2 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 CCC71755.1 - 3.5e-25 88.2 8.9 3.5e-25 88.2 6.2 4.6 4 1 1 5 5 3 1 Signal peptide binding domain SRP54_N PF02881.14 CCC71755.1 - 1.2e-15 57.3 0.6 3.6e-15 55.8 0.4 1.9 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 CCC71755.1 - 8.1e-06 25.3 1.3 3.2e-05 23.4 0.3 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CCC71755.1 - 1e-05 25.4 0.1 3.4e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_31 PF13614.1 CCC71755.1 - 1.2e-05 25.2 0.0 0.047 13.6 0.0 3.0 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CCC71755.1 - 5.4e-05 22.9 0.1 0.00017 21.3 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 CCC71755.1 - 0.00019 20.8 2.2 0.00041 19.8 0.1 2.6 3 1 0 3 3 3 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 CCC71755.1 - 0.00058 20.6 0.0 0.0013 19.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 CCC71755.1 - 0.0021 17.3 4.4 2.7 7.1 0.0 3.9 4 0 0 4 4 4 2 Signal recognition particle receptor beta subunit AAA_18 PF13238.1 CCC71755.1 - 0.0062 16.8 0.0 0.021 15.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 CCC71755.1 - 0.01 15.5 0.4 0.021 14.4 0.0 1.7 2 0 0 2 2 1 0 Adenylylsulphate kinase AAA_22 PF13401.1 CCC71755.1 - 0.011 15.9 0.2 0.074 13.1 0.1 2.7 1 1 1 2 2 2 0 AAA domain VirE PF05272.6 CCC71755.1 - 0.012 15.1 0.0 0.028 13.8 0.0 1.6 1 0 0 1 1 1 0 Virulence-associated protein E ATP_bind_1 PF03029.12 CCC71755.1 - 0.015 14.8 0.1 0.053 13.0 0.1 2.0 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 CCC71755.1 - 0.03 13.7 0.3 0.059 12.8 0.2 1.5 1 1 0 1 1 1 0 AAA-like domain KTI12 PF08433.5 CCC71755.1 - 0.03 13.5 0.3 0.54 9.4 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ArgK PF03308.11 CCC71755.1 - 0.032 12.9 1.0 0.079 11.7 0.0 2.1 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 CCC71755.1 - 0.051 13.5 0.0 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 CCC71755.1 - 0.059 12.4 0.0 0.14 11.1 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin DUF3941 PF13081.1 CCC71755.1 - 0.083 12.8 0.1 0.25 11.3 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3941) AAA PF00004.24 CCC71755.1 - 1.1 9.4 4.2 2.4 8.3 0.6 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TFIIB PF00382.14 CCC71756.1 - 6.7e-43 144.3 2.6 1.7e-27 95.0 0.7 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 CCC71756.1 - 9.4e-14 50.4 0.5 1.8e-13 49.5 0.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding Atg14 PF10186.4 CCC71757.1 - 1.2e-34 119.6 12.9 2.5e-34 118.6 9.0 1.5 1 1 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 PMBR PF09373.5 CCC71757.1 - 0.071 13.0 0.9 5.6 7.0 0.0 3.3 4 0 0 4 4 4 0 Pseudomurein-binding repeat zf-B_box PF00643.19 CCC71757.1 - 0.25 11.2 1.6 0.5 10.2 1.1 1.5 1 0 0 1 1 1 0 B-box zinc finger Fib_alpha PF08702.5 CCC71757.1 - 0.96 9.5 11.9 0.12 12.4 3.5 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Ndc1_Nup PF09531.5 CCC71758.1 - 0.0016 16.9 2.8 0.0026 16.2 1.9 1.3 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup PH PF00169.24 CCC71759.1 - 1.4e-09 38.1 5.9 6e-06 26.4 0.2 3.0 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 CCC71759.1 - 0.0062 16.7 4.5 1.6 8.9 1.0 3.3 2 2 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 CCC71759.1 - 0.087 12.7 1.4 2.5 8.0 0.1 2.6 3 0 0 3 3 3 0 PH domain ATP-synt_ab PF00006.20 CCC71760.1 - 1.6e-60 204.2 0.0 2.2e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 CCC71760.1 - 1.6e-16 60.8 0.3 3.1e-16 59.8 0.2 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 CCC71760.1 - 3.5e-14 52.7 1.0 7.8e-14 51.6 0.7 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 CCC71760.1 - 8e-05 22.4 0.6 0.00027 20.7 0.4 1.9 1 0 0 1 1 1 1 HAS barrel domain Glyco_transf_20 PF00982.16 CCC71761.1 - 4.8e-201 668.3 0.0 5.5e-201 668.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 CCC71761.1 - 0.00024 20.5 0.6 0.46 9.8 0.1 3.2 2 1 0 2 2 2 2 Glycosyl transferases group 1 PP2C PF00481.16 CCC71762.1 - 3.3e-65 219.9 0.0 6.2e-61 206.0 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 CCC71762.1 - 0.00024 20.5 0.0 0.0027 17.1 0.0 2.4 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 CCC71762.1 - 0.0065 16.2 0.0 0.77 9.4 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Tau95 PF09734.4 CCC71763.1 - 7.2e-65 219.3 1.5 9.4e-65 218.9 1.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit BUD22 PF09073.5 CCC71763.1 - 1.8 7.5 7.7 2.7 6.9 5.3 1.2 1 0 0 1 1 1 0 BUD22 Ribosomal_L31 PF01197.13 CCC71764.1 - 0.098 12.6 0.0 0.27 11.2 0.0 1.8 2 0 0 2 2 2 0 Ribosomal protein L31 BHD_1 PF10403.4 CCC71764.1 - 0.11 12.0 0.2 0.44 10.0 0.0 2.1 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 tRNA-synt_2b PF00587.20 CCC71765.1 - 6.4e-72 240.7 0.1 1.2e-71 239.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 CCC71765.1 - 7.3e-23 80.3 0.5 2.4e-22 78.6 0.1 2.2 2 0 0 2 2 2 1 Anticodon binding domain Surf_Ag_VNR PF07244.10 CCC71766.1 - 0.037 14.4 0.5 0.099 13.0 0.1 1.9 2 0 0 2 2 2 0 Surface antigen variable number repeat DUF148 PF02520.12 CCC71766.1 - 0.049 13.4 0.7 0.23 11.2 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 Syntaxin-18_N PF10496.4 CCC71766.1 - 0.12 12.2 0.6 0.34 10.7 0.2 1.9 1 1 1 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus RRM_1 PF00076.17 CCC71767.1 - 1.9e-10 40.2 0.0 5.7e-05 22.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 CCC71767.1 - 7.1e-10 38.7 0.0 0.0011 18.9 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 CCC71767.1 - 8.2e-07 28.7 0.0 0.03 14.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Trans_reg_C PF00486.23 CCC71767.1 - 0.053 13.4 0.6 0.1 12.5 0.4 1.4 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal DUF3343 PF11823.3 CCC71767.1 - 0.58 9.4 0.0 0.58 9.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3343) GTP_EFTU PF00009.22 CCC71768.1 - 2e-57 193.6 0.0 2.8e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 CCC71768.1 - 1.5e-35 121.3 0.0 4.3e-35 119.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 CCC71768.1 - 3e-17 62.4 2.1 3e-17 62.4 1.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 CCC71768.1 - 2e-05 24.1 0.6 2e-05 24.1 0.4 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 CCC71768.1 - 0.0012 18.7 0.2 0.0036 17.2 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase CIMR PF00878.13 CCC71769.1 - 4e-10 39.6 1.0 1.9e-05 24.4 0.0 3.1 3 0 0 3 3 3 3 Cation-independent mannose-6-phosphate receptor repeat PRKCSH_1 PF13015.1 CCC71769.1 - 8.7e-05 22.0 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Transketolase_N PF00456.16 CCC71771.1 - 1.5e-150 500.6 0.0 6.6e-150 498.5 0.0 1.8 2 0 0 2 2 2 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 CCC71771.1 - 2.4e-45 154.1 0.0 3.8e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 CCC71771.1 - 6.7e-12 45.4 0.0 1.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 CCC71771.1 - 1.1e-06 27.7 0.2 1.2e-05 24.3 0.1 2.4 2 1 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 CCC71771.1 - 4.4e-05 22.3 0.1 0.00032 19.5 0.0 2.2 3 0 0 3 3 3 1 Dehydrogenase E1 component AMP-binding PF00501.23 CCC71772.1 - 4e-71 239.6 0.0 5.2e-71 239.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 CCC71772.1 - 1.3e-69 233.8 0.0 2e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 CCC71772.1 - 3.4e-14 52.8 0.0 5e-13 49.1 0.0 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Epimerase PF01370.16 CCC71772.1 - 8.4e-11 41.7 0.0 1.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 CCC71772.1 - 2.5e-06 28.3 0.0 1.5e-05 25.8 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 CCC71772.1 - 6.7e-06 24.9 0.0 2.7e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 CCC71772.1 - 0.014 15.3 0.0 0.23 11.4 0.0 2.3 1 1 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 CCC71772.1 - 0.038 13.2 0.0 0.069 12.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 CCC71772.1 - 0.064 12.1 0.0 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Condensation PF00668.15 CCC71772.1 - 0.15 10.8 3.3 0.98 8.1 0.1 2.2 1 1 1 2 2 2 0 Condensation domain RmlD_sub_bind PF04321.12 CCC71772.1 - 0.19 10.5 0.0 2 7.2 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain SNF2_N PF00176.18 CCC71773.1 - 2.3e-75 253.2 0.8 3.4e-75 252.6 0.5 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCC71773.1 - 5.9e-11 42.0 0.0 2e-10 40.3 0.0 2.0 2 0 0 2 2 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 CCC71773.1 - 3e-09 36.5 0.1 6.1e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 CCC71773.1 - 8.3e-09 34.9 10.7 8.3e-09 34.9 7.4 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCC71773.1 - 3.4e-05 23.6 9.1 3.4e-05 23.6 6.3 2.3 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 CCC71773.1 - 5.9e-05 22.8 8.6 5.9e-05 22.8 6.0 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 CCC71773.1 - 0.00012 22.0 9.3 0.00012 22.0 6.5 2.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Nop14 PF04147.7 CCC71773.1 - 0.0045 14.9 17.2 0.0065 14.4 11.9 1.1 1 0 0 1 1 1 1 Nop14-like family zf-RING_6 PF14835.1 CCC71773.1 - 0.0052 16.5 2.3 0.017 14.8 1.6 1.9 1 0 0 1 1 1 1 zf-RING of BARD1-type protein AAA_34 PF13872.1 CCC71773.1 - 0.0063 15.3 0.0 0.04 12.6 0.0 2.0 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 zf-Nse PF11789.3 CCC71773.1 - 0.009 15.5 6.5 0.028 13.9 4.5 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Zn_Tnp_IS91 PF14319.1 CCC71773.1 - 0.072 12.5 14.1 0.2 11.1 2.4 2.5 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_UBOX PF13445.1 CCC71773.1 - 0.17 11.6 5.0 0.53 10.0 3.5 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DUF4182 PF13790.1 CCC71773.1 - 0.56 10.0 6.6 1.7 8.5 0.3 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4182) EnY2 PF10163.4 CCC71774.1 - 3.1e-26 91.1 2.7 3.5e-26 90.9 1.9 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF3206 PF11472.3 CCC71774.1 - 0.094 12.4 0.2 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) NUDIX PF00293.23 CCC71775.1 - 5.6e-17 61.6 0.0 3.9e-16 58.9 0.0 2.0 2 0 0 2 2 2 1 NUDIX domain Spermine_synth PF01564.12 CCC71776.1 - 1.1e-101 338.9 0.1 1.3e-101 338.7 0.1 1.0 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 CCC71776.1 - 0.00073 19.1 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 CCC71776.1 - 0.0022 18.5 0.0 0.0038 17.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF43 PF01861.11 CCC71776.1 - 0.0035 16.3 0.0 0.0064 15.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 CCC71776.1 - 0.0042 17.5 0.1 0.017 15.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 CCC71776.1 - 0.018 14.7 0.0 0.033 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 CCC71776.1 - 0.091 11.9 0.1 0.85 8.7 0.0 2.1 1 1 1 2 2 2 0 O-methyltransferase Glyco_trans_1_4 PF13692.1 CCC71777.1 - 1.8e-12 47.5 0.0 3.7e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 CCC71777.1 - 6.2e-10 38.7 0.0 1e-09 38.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 CCC71777.1 - 4.7e-06 26.7 0.0 9.8e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 EF-hand_1 PF00036.27 CCC71778.1 - 1.1e-30 102.5 3.8 1.7e-08 33.1 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 CCC71778.1 - 2.5e-27 94.8 0.4 1.3e-13 50.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 CCC71778.1 - 1e-25 87.2 2.7 6.3e-08 31.8 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 CCC71778.1 - 3.1e-18 65.1 5.3 3.9e-07 29.5 0.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 CCC71778.1 - 1.5e-17 62.0 3.3 1.9e-07 30.1 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 CCC71778.1 - 2.9e-12 46.3 0.0 2.7e-08 33.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 CCC71778.1 - 1.6e-06 28.0 0.0 0.00067 19.6 0.0 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 CCC71778.1 - 4.6e-06 26.1 0.0 0.13 11.8 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) Caleosin PF05042.8 CCC71778.1 - 0.00046 19.8 0.0 0.25 10.8 0.0 2.2 2 0 0 2 2 2 2 Caleosin related protein EF-hand_4 PF12763.2 CCC71778.1 - 0.0017 18.0 0.3 0.0049 16.5 0.1 1.8 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand TerB PF05099.8 CCC71778.1 - 0.0088 15.7 0.1 0.63 9.7 0.0 2.3 2 1 0 2 2 2 1 Tellurite resistance protein TerB DUF853 PF05872.7 CCC71778.1 - 0.012 13.9 0.2 0.032 12.5 0.1 1.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF853) ERAP1_C PF11838.3 CCC71778.1 - 0.045 12.9 0.1 0.062 12.5 0.0 1.3 1 1 0 1 1 1 0 ERAP1-like C-terminal domain TRCF PF03461.10 CCC71778.1 - 0.068 13.1 0.1 0.15 12.0 0.0 1.6 1 1 0 1 1 1 0 TRCF domain LNS2 PF08235.8 CCC71778.1 - 0.11 12.0 0.0 3.2 7.2 0.0 2.0 1 1 1 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) RNA_pol_Rpb4 PF03874.11 CCC71778.1 - 0.11 12.5 0.8 0.78 9.7 0.0 2.3 2 1 0 2 2 2 0 RNA polymerase Rpb4 Fe-S_biosyn PF01521.15 CCC71780.1 - 3.5e-15 55.9 0.1 1e-13 51.1 0.1 2.0 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF3797 PF12677.2 CCC71780.1 - 0.17 11.5 0.9 0.71 9.5 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3797) Pho88 PF10032.4 CCC71781.1 - 3e-64 215.8 1.1 3.7e-64 215.4 0.7 1.1 1 0 0 1 1 1 1 Phosphate transport (Pho88) Vac_ImportDeg PF09783.4 CCC71782.1 - 1.8e-59 200.2 6.0 2.6e-59 199.6 4.1 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mito_carr PF00153.22 CCC71783.1 - 9.1e-60 198.3 0.4 4.1e-20 71.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-C2H2 PF00096.21 CCC71784.1 - 0.0018 18.4 6.6 0.59 10.5 0.9 2.8 2 1 1 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC71784.1 - 0.015 15.5 6.2 1.6 9.2 0.4 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger TAXi_N PF14543.1 CCC71784.1 - 0.54 10.2 6.8 0.84 9.5 1.7 2.1 1 1 1 2 2 2 0 Xylanase inhibitor N-terminal Vps51 PF08700.6 CCC71786.1 - 2.8e-10 39.8 2.3 2.8e-10 39.8 1.6 3.4 4 0 0 4 4 4 1 Vps51/Vps67 COG2 PF06148.6 CCC71786.1 - 9.6e-06 25.4 1.7 9.6e-06 25.4 1.2 3.7 4 0 0 4 4 4 2 COG (conserved oligomeric Golgi) complex component, COG2 Fes1 PF08609.5 CCC71787.1 - 6.4e-25 87.4 2.4 2e-24 85.8 0.3 2.6 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 V-ATPase_H_N PF03224.9 CCC71787.1 - 8.2e-05 21.8 2.3 0.00013 21.1 0.3 1.8 1 1 1 2 2 2 1 V-ATPase subunit H HEAT_2 PF13646.1 CCC71787.1 - 0.00016 21.8 0.0 0.0071 16.6 0.0 2.9 1 1 1 2 2 2 1 HEAT repeats Arm PF00514.18 CCC71787.1 - 0.00019 21.1 0.0 0.0036 17.0 0.0 2.9 2 1 0 2 2 2 1 Armadillo/beta-catenin-like repeat V-ATPase_H_C PF11698.3 CCC71787.1 - 0.026 14.4 1.1 0.071 13.0 0.3 2.0 1 1 1 2 2 2 0 V-ATPase subunit H DUF3361 PF11841.3 CCC71787.1 - 0.03 14.0 1.0 0.086 12.5 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) DUF2454 PF10521.4 CCC71787.1 - 0.031 13.2 0.7 0.065 12.2 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2454) HEAT PF02985.17 CCC71787.1 - 0.035 14.1 0.0 0.17 12.0 0.0 2.2 1 0 0 1 1 1 0 HEAT repeat IBN_N PF03810.14 CCC71787.1 - 0.038 13.8 0.5 0.34 10.8 0.2 2.5 2 1 0 2 2 2 0 Importin-beta N-terminal domain DUF4042 PF13251.1 CCC71787.1 - 0.046 13.1 0.4 0.76 9.2 0.0 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4042) FPL PF09758.4 CCC71787.1 - 4.2 7.1 8.6 1.5 8.6 1.8 2.5 2 1 1 3 3 3 0 Uncharacterised conserved protein ERCC4 PF02732.10 CCC71788.1 - 5.6e-06 26.1 5.3 5.6e-06 26.1 3.7 2.5 1 1 1 2 2 2 1 ERCC4 domain PAS_10 PF13596.1 CCC71788.1 - 0.19 12.0 2.5 0.23 11.7 0.1 2.4 2 0 0 2 2 2 0 PAS domain Pkinase PF00069.20 CCC71789.1 - 3.3e-27 95.2 0.1 7e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 CCC71789.1 - 3.9e-13 48.2 3.9 0.054 13.5 0.0 6.4 6 0 0 6 6 6 4 HEAT repeat Pkinase_Tyr PF07714.12 CCC71789.1 - 1.3e-11 44.1 0.0 2.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 CCC71789.1 - 8.8e-08 32.3 0.0 0.026 14.7 0.0 3.2 1 1 4 5 5 5 4 HEAT repeats WD40 PF00400.27 CCC71789.1 - 0.0065 16.3 0.3 1 9.3 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat HEAT_EZ PF13513.1 CCC71789.1 - 0.0069 16.8 1.0 6.2 7.4 0.0 4.1 2 2 1 4 4 4 1 HEAT-like repeat RasGEF_N_2 PF14663.1 CCC71789.1 - 0.047 13.6 0.1 1.1 9.2 0.0 3.1 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Kdo PF06293.9 CCC71789.1 - 0.07 12.1 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 CCC71789.1 - 0.54 9.9 0.0 1 9.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Epsilon_antitox PF08998.6 CCC71789.1 - 6.1 6.8 10.9 0.29 11.1 0.3 3.8 3 1 0 3 3 3 0 Bacterial epsilon antitoxin 4HBT_2 PF13279.1 CCC71790.1 - 3.9e-09 37.0 0.0 5.4e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily RXT2_N PF08595.6 CCC71791.1 - 3.8e-31 107.8 3.0 3.8e-31 107.8 2.1 2.5 2 0 0 2 2 2 2 RXT2-like, N-terminal TTL PF03133.10 CCC71792.1 - 2.2e-79 266.4 5.2 3.2e-79 265.9 3.6 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 CCC71792.1 - 2.9e-39 134.4 0.0 6.3e-39 133.3 0.0 1.6 1 0 0 1 1 1 1 Survival protein SurE ATP-grasp_4 PF13535.1 CCC71792.1 - 6.6e-05 22.7 0.0 0.00019 21.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_YheCD PF14398.1 CCC71792.1 - 0.00013 20.8 0.0 0.075 11.8 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_Ter PF15632.1 CCC71792.1 - 0.057 12.1 0.0 0.13 10.9 0.0 1.5 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon zf-Tim10_DDP PF02953.10 CCC71793.1 - 5.5e-14 51.1 1.1 6.9e-14 50.8 0.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger HMG_box PF00505.14 CCC71794.1 - 1.1e-22 80.0 0.2 1.5e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 CCC71794.1 - 1.6e-18 66.8 0.2 2.1e-18 66.4 0.1 1.2 1 0 0 1 1 1 1 HMG-box domain DUF4272 PF14094.1 CCC71794.1 - 0.04 12.9 0.0 0.043 12.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) PCNA_N PF00705.13 CCC71795.1 - 5.9e-52 174.4 1.5 1.1e-51 173.6 1.1 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 CCC71795.1 - 4.6e-47 159.1 0.0 1.2e-46 157.8 0.0 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 CCC71795.1 - 0.001 18.2 0.0 0.0012 18.0 0.0 1.1 1 0 0 1 1 1 1 Rad9 FOP_dimer PF09398.5 CCC71795.1 - 0.069 13.1 0.2 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 FOP N terminal dimerisation domain FAD_binding_1 PF00667.15 CCC71796.1 - 1.9e-31 109.2 0.0 4.6e-31 107.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 CCC71796.1 - 2.9e-24 85.6 0.0 5.3e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 CCC71796.1 - 2.9e-13 50.3 0.0 6.6e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 CCC71796.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Flavodoxin_3 PF12641.2 CCC71796.1 - 0.12 11.8 0.0 3.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Flavodoxin domain Ala_racemase_N PF01168.15 CCC71797.1 - 9.2e-39 133.2 0.0 1.1e-38 132.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Anoctamin PF04547.7 CCC71798.1 - 1.6e-40 139.1 41.5 1.6e-39 135.8 28.8 2.3 1 1 0 1 1 1 1 Calcium-activated chloride channel KH_1 PF00013.24 CCC71800.1 - 1.6e-21 75.7 7.2 1e-08 34.7 0.1 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 CCC71800.1 - 8.2e-15 54.0 4.8 4.9e-06 26.0 0.0 3.5 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 CCC71800.1 - 0.00021 20.7 1.7 4.2 6.9 0.1 3.8 4 1 0 4 4 4 3 KH domain RseA_C PF03873.8 CCC71800.1 - 1.7 8.5 4.9 4.1 7.3 3.4 1.6 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Mito_carr PF00153.22 CCC71801.1 - 3.4e-70 231.8 7.0 3e-24 84.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L19e PF01280.15 CCC71802.1 - 4.2e-58 195.3 9.1 4.2e-58 195.3 6.3 1.6 2 0 0 2 2 2 1 Ribosomal protein L19e FTHFS PF01268.14 CCC71803.1 - 2.5e-255 847.7 0.8 3.2e-255 847.3 0.5 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 CCC71803.1 - 1.3e-69 232.4 0.2 1.3e-69 232.4 0.1 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 CCC71803.1 - 9e-37 125.6 0.6 2.9e-36 124.0 0.4 1.9 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GspL_C PF12693.2 CCC71803.1 - 0.098 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 GspL periplasmic domain TEA PF01285.13 CCC71804.1 - 1.7e-34 119.7 4.7 1.7e-34 119.7 3.2 2.7 1 1 0 2 2 2 1 TEA/ATTS domain family CBF PF03914.12 CCC71805.1 - 1.6e-44 151.2 1.9 6.6e-44 149.2 0.1 2.8 2 0 0 2 2 2 1 CBF/Mak21 family Bromodomain PF00439.20 CCC71806.1 - 2.3e-17 62.6 0.5 2.3e-17 62.6 0.3 2.3 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 CCC71806.1 - 1.4e-07 31.1 0.0 3.7e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 Bromodomain associated Ovate PF04844.8 CCC71807.1 - 0.11 12.3 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Transcriptional repressor, ovate AAA PF00004.24 CCC71808.1 - 8.2e-52 174.8 0.0 3.9e-38 130.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 CCC71808.1 - 3e-16 59.1 0.0 7.9e-16 57.7 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_22 PF13401.1 CCC71808.1 - 7.6e-10 39.0 0.1 0.0012 19.0 0.1 3.3 2 1 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 CCC71808.1 - 9.6e-10 37.9 1.3 2.4e-09 36.6 0.2 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_19 PF13245.1 CCC71808.1 - 2e-09 37.0 0.3 0.0018 17.9 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_17 PF13207.1 CCC71808.1 - 1.4e-08 35.5 0.1 0.0054 17.5 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 CCC71808.1 - 1.4e-07 31.3 0.2 0.0016 18.1 0.0 3.4 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 CCC71808.1 - 1.4e-07 31.6 0.0 0.013 15.4 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain TIP49 PF06068.8 CCC71808.1 - 1.5e-07 30.4 0.1 0.0031 16.3 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 CCC71808.1 - 2.1e-07 30.5 0.1 0.024 14.0 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 CCC71808.1 - 2.4e-07 30.1 0.1 0.0021 17.2 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 CCC71808.1 - 3.3e-07 30.2 0.0 0.0056 16.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 CCC71808.1 - 9.8e-07 29.1 0.0 0.023 15.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 CCC71808.1 - 2.1e-06 26.9 0.3 0.056 12.4 0.0 3.1 3 1 1 4 4 4 2 Holliday junction DNA helicase ruvB N-terminus PhoH PF02562.11 CCC71808.1 - 9.2e-06 25.0 0.0 0.02 14.1 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_14 PF13173.1 CCC71808.1 - 1.3e-05 25.0 0.0 0.015 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 CCC71808.1 - 1.5e-05 25.0 0.1 0.49 10.5 0.0 3.4 3 0 0 3 3 3 2 RNA helicase AAA_2 PF07724.9 CCC71808.1 - 2.8e-05 24.1 0.0 0.0023 17.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ABC_tran PF00005.22 CCC71808.1 - 3.8e-05 23.9 0.2 0.057 13.7 0.0 2.6 2 0 0 2 2 2 1 ABC transporter NACHT PF05729.7 CCC71808.1 - 4.4e-05 23.2 1.9 0.052 13.1 0.0 3.6 4 1 0 4 4 3 1 NACHT domain Zeta_toxin PF06414.7 CCC71808.1 - 6.9e-05 22.0 0.0 0.045 12.8 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 CCC71808.1 - 7.9e-05 22.2 0.0 0.0095 15.3 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain AAA_11 PF13086.1 CCC71808.1 - 8.4e-05 22.2 0.0 0.076 12.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF2075 PF09848.4 CCC71808.1 - 0.00017 20.6 0.0 0.29 10.0 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 CCC71808.1 - 0.0003 20.2 0.0 0.46 9.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 CCC71808.1 - 0.00087 18.7 6.1 0.18 11.2 0.1 3.9 2 2 1 4 4 4 1 AAA domain NB-ARC PF00931.17 CCC71808.1 - 0.0009 18.1 0.0 0.22 10.3 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.1 CCC71808.1 - 0.0012 18.4 1.5 0.82 9.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_28 PF13521.1 CCC71808.1 - 0.0014 18.6 0.0 2.2 8.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 CCC71808.1 - 0.0015 18.9 1.0 0.74 10.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 CCC71808.1 - 0.0019 17.3 0.2 0.45 9.5 0.1 2.6 2 0 0 2 2 2 1 KaiC AAA_3 PF07726.6 CCC71808.1 - 0.0022 17.6 0.0 0.42 10.2 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 CCC71808.1 - 0.0026 17.7 0.6 5.4 7.0 0.1 3.7 2 1 1 3 3 3 0 Sigma-54 interaction domain ResIII PF04851.10 CCC71808.1 - 0.0032 17.3 0.0 0.87 9.3 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCC71808.1 - 0.015 14.7 0.6 26 4.2 0.0 3.8 2 2 1 4 4 4 0 DEAD/DEAH box helicase AAA_30 PF13604.1 CCC71808.1 - 0.016 14.7 0.0 5.2 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 CCC71808.1 - 0.019 13.8 0.1 4 6.2 0.0 2.6 3 0 0 3 3 2 0 Type II/IV secretion system protein Bac_DnaA PF00308.13 CCC71808.1 - 0.019 14.5 0.0 2 7.9 0.0 3.1 3 0 0 3 3 3 0 Bacterial dnaA protein KTI12 PF08433.5 CCC71808.1 - 0.022 13.9 0.0 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_29 PF13555.1 CCC71808.1 - 0.025 14.1 0.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 CCC71808.1 - 0.026 14.1 0.7 8.3 6.0 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase Parvo_NS1 PF01057.12 CCC71808.1 - 0.036 12.9 0.0 7.4 5.3 0.0 2.3 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 CCC71808.1 - 0.051 13.1 0.0 4.7 6.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 CCC71808.1 - 0.064 12.6 0.3 3.4 7.0 0.0 2.9 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.10 CCC71808.1 - 0.082 12.6 0.1 16 5.1 0.0 2.7 2 0 0 2 2 2 0 NTPase PCI PF01399.22 CCC71809.1 - 6e-08 32.9 7.4 7e-08 32.7 0.3 3.2 3 0 0 3 3 3 1 PCI domain PAF-AH_p_II PF03403.8 CCC71809.1 - 0.09 11.0 6.6 0.036 12.3 2.1 2.1 1 1 1 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Recep_L_domain PF01030.19 CCC71810.1 - 4.4e-10 39.5 7.7 0.0033 17.3 0.0 4.7 1 1 3 4 4 4 4 Receptor L domain Ecm33 PF12454.3 CCC71810.1 - 0.41 10.5 7.2 0.25 11.2 3.0 2.3 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein CDK2AP PF09806.4 CCC71810.1 - 1.7 8.8 10.5 1 9.5 4.0 2.5 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein UQ_con PF00179.21 CCC71811.1 - 1.4e-43 147.6 0.2 1.9e-43 147.2 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 CCC71811.1 - 0.0037 17.0 0.1 0.011 15.4 0.0 1.8 1 1 0 1 1 1 1 Prokaryotic E2 family B TSGP1 PF07771.6 CCC71811.1 - 0.019 14.8 0.5 0.043 13.6 0.4 1.5 1 0 0 1 1 1 0 Tick salivary peptide group 1 Dfp1_Him1_M PF08630.5 CCC71813.1 - 4.5e-19 68.4 0.7 3.5e-14 52.6 0.1 2.7 1 1 1 2 2 2 2 Dfp1/Him1, central region zf-DBF PF07535.7 CCC71813.1 - 0.028 14.0 0.0 0.067 12.8 0.0 1.6 1 0 0 1 1 1 0 DBF zinc finger zf-C2H2 PF00096.21 CCC71814.1 - 1.1e-09 37.9 8.2 0.00036 20.6 2.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC71814.1 - 5.8e-06 26.2 7.0 0.031 14.5 1.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 CCC71814.1 - 0.00023 21.2 1.0 0.021 15.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 CCC71814.1 - 0.0026 17.9 8.9 0.007 16.6 0.1 2.9 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 CCC71814.1 - 0.0076 16.3 0.4 0.02 15.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 CCC71814.1 - 0.31 11.3 4.3 4.1 7.8 1.8 2.6 2 0 0 2 2 2 0 C2H2-type zinc-finger domain TPR_2 PF07719.12 CCC71817.1 - 6.8e-17 59.9 5.4 0.00029 20.5 0.1 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 CCC71817.1 - 9.5e-16 56.3 9.2 0.00028 20.4 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCC71817.1 - 4.4e-15 54.5 8.4 0.005 16.3 0.0 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 CCC71817.1 - 1.2e-13 50.7 3.3 4.9e-07 29.5 0.0 4.5 2 2 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 CCC71817.1 - 3.9e-13 48.8 12.5 3.1e-06 26.7 0.2 5.1 4 1 2 6 6 6 5 TPR repeat TPR_14 PF13428.1 CCC71817.1 - 1.5e-11 43.8 1.6 0.054 14.1 0.0 5.7 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.1 CCC71817.1 - 2.3e-08 34.4 0.7 2.1 9.0 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 CCC71817.1 - 3.5e-08 32.6 0.5 0.4 10.6 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.1 CCC71817.1 - 1e-07 32.1 3.4 0.65 10.3 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 CCC71817.1 - 9.3e-07 28.9 8.1 0.12 12.5 0.2 4.8 3 2 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 CCC71817.1 - 1.4e-06 28.0 12.6 0.0052 16.8 0.0 6.8 7 0 0 7 7 7 1 Tetratricopeptide repeat Apc5 PF12862.2 CCC71817.1 - 1.5e-06 27.9 2.5 0.0033 17.2 0.2 3.3 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 5 TPR_6 PF13174.1 CCC71817.1 - 9.1e-05 22.6 3.2 18 6.0 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3856 PF12968.2 CCC71817.1 - 0.00047 20.0 0.3 0.0061 16.3 0.0 2.6 2 1 1 3 3 3 1 Domain of Unknown Function (DUF3856) TPR_15 PF13429.1 CCC71817.1 - 0.0015 17.6 1.3 8 5.4 0.0 4.1 2 1 1 4 4 4 1 Tetratricopeptide repeat RPN7 PF10602.4 CCC71817.1 - 0.005 16.2 0.1 6.7 6.0 0.0 3.1 2 1 0 3 3 3 1 26S proteasome subunit RPN7 ChAPs PF09295.5 CCC71817.1 - 0.018 13.8 8.6 2.8 6.5 0.6 4.1 2 2 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) SNF2_N PF00176.18 CCC71819.1 - 2.3e-61 207.2 0.0 8.1e-61 205.4 0.0 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 CCC71819.1 - 7.2e-12 45.0 0.0 1.7e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 CCC71819.1 - 2e-08 34.2 0.0 8.6e-08 32.2 0.0 2.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 CCC71819.1 - 7.9e-08 31.9 0.0 2.9e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2439 PF10382.4 CCC71819.1 - 1.9e-05 24.7 0.1 8.1e-05 22.7 0.1 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) AAA_22 PF13401.1 CCC71819.1 - 7.6e-05 22.8 0.1 0.13 12.3 0.0 3.0 2 1 0 2 2 2 2 AAA domain AA_permease PF00324.16 CCC71820.1 - 1.4e-120 402.8 33.9 1.6e-120 402.6 23.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC71820.1 - 2.4e-36 125.2 34.7 2.8e-36 124.9 24.0 1.0 1 0 0 1 1 1 1 Amino acid permease Microtub_bind PF13931.1 CCC71820.1 - 1 9.5 4.9 0.48 10.5 0.2 2.0 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding AA_permease PF00324.16 CCC71821.1 - 8.1e-125 416.8 38.3 9.9e-125 416.5 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC71821.1 - 1.3e-37 129.3 38.0 1.8e-37 128.9 26.4 1.1 1 0 0 1 1 1 1 Amino acid permease SRP1_TIP1 PF00660.12 CCC71822.1 - 2.3e-35 120.5 0.6 5.1e-35 119.4 0.4 1.5 1 0 0 1 1 1 1 Seripauperin and TIP1 family PIR PF00399.14 CCC71822.1 - 3.7e-07 29.2 5.9 3.7e-07 29.2 4.1 3.0 3 0 0 3 3 3 1 Yeast PIR protein repeat Pox_A12 PF04651.8 CCC71822.1 - 0.088 12.9 7.9 0.15 12.1 5.5 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Med3 PF11593.3 CCC71822.1 - 0.16 11.2 16.2 0.15 11.2 11.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Macoilin PF09726.4 CCC71822.1 - 0.39 8.9 6.4 0.44 8.7 4.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Herpes_TAF50 PF03326.8 CCC71822.1 - 1.1 8.1 10.1 1.2 7.9 7.0 1.1 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) zf-H2C2_2 PF13465.1 CCC71824.1 - 1.3e-06 28.4 13.7 4.3e-06 26.7 2.0 3.5 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC71824.1 - 9.4e-05 22.4 12.9 0.066 13.5 4.0 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCC71824.1 - 0.00025 21.2 17.8 0.0023 18.1 1.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 CCC71824.1 - 0.62 10.3 9.0 0.38 11.0 0.7 2.9 2 0 0 2 2 2 0 Zinc-finger of C2H2 type DUF3824 PF12868.2 CCC71824.1 - 2.2 9.2 5.9 1.5 9.7 3.0 1.6 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) zf-RING-like PF08746.6 CCC71824.1 - 3.6 7.6 9.6 0.063 13.2 1.7 1.8 2 0 0 2 2 2 0 RING-like domain FtsJ PF01728.14 CCC71827.1 - 1.2e-63 214.3 0.1 1.6e-63 213.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 CCC71827.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain ORC2 PF04084.9 CCC71828.1 - 8.6e-103 343.5 5.5 1.2e-102 343.0 3.8 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 2 AT_hook PF02178.14 CCC71828.1 - 2.8e-06 26.3 43.1 0.061 13.0 2.1 5.0 4 0 0 4 4 4 4 AT hook motif CHZ PF09649.5 CCC71828.1 - 0.026 13.7 0.3 0.079 12.1 0.2 1.8 1 0 0 1 1 1 0 Histone chaperone domain CHZ DUF3317 PF11779.3 CCC71829.1 - 2.3 7.7 8.3 3.1 7.3 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) UCH PF00443.24 CCC71830.1 - 5.9e-52 176.4 2.3 5.9e-52 176.4 0.5 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC71830.1 - 6e-28 98.1 4.2 6e-28 98.1 2.9 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 CCC71830.1 - 2.1e-21 75.8 17.2 7.1e-21 74.0 3.7 3.0 2 0 0 2 2 2 2 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.26 CCC71830.1 - 2e-10 40.1 0.0 0.00023 20.9 0.0 2.8 2 0 0 2 2 2 2 UBA/TS-N domain Sec2p PF06428.6 CCC71831.1 - 0.0014 18.4 0.5 0.0014 18.4 0.4 2.3 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF342 PF03961.8 CCC71831.1 - 0.061 11.7 7.6 1.4 7.2 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DivIC PF04977.10 CCC71831.1 - 0.086 12.3 7.3 4.1 6.9 1.3 3.4 3 0 0 3 3 3 0 Septum formation initiator DUF4407 PF14362.1 CCC71831.1 - 1.9 7.3 6.9 0.099 11.5 0.6 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) TMF_DNA_bd PF12329.3 CCC71831.1 - 5.6 6.8 14.8 0.22 11.3 2.2 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding PXPV PF12778.2 CCC71832.1 - 0.38 10.4 10.6 0.82 9.4 7.4 1.4 1 1 0 1 1 1 0 PXPV repeat (3 copies) Cellulase PF00150.13 CCC71833.1 - 9.3e-12 44.7 4.7 9.3e-12 44.7 3.3 2.4 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Bac_rhodopsin PF01036.13 CCC71834.1 - 1.5e-43 148.7 17.7 1.9e-43 148.3 12.3 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein PgaD PF13994.1 CCC71834.1 - 2.2 7.7 6.9 1.1 8.7 0.8 2.5 2 1 0 2 2 2 0 PgaD-like protein SGL PF08450.7 CCC71835.1 - 5.4e-54 183.1 0.4 6.5e-54 182.9 0.3 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 CCC71835.1 - 2.2e-06 27.5 0.1 0.023 14.6 0.0 4.0 4 0 0 4 4 4 2 Arylesterase DUF1752 PF08550.5 CCC71836.1 - 0.0067 15.9 1.1 0.0067 15.9 0.7 2.2 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1752) Myb_DNA-binding PF00249.26 CCC71837.1 - 4.8e-17 61.7 21.1 9.8e-12 44.7 0.4 6.1 7 0 0 7 7 7 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 CCC71837.1 - 7e-17 61.2 26.1 2.3e-14 53.2 2.2 5.7 4 2 0 4 4 4 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 CCC71837.1 - 0.0018 18.3 11.6 0.22 11.6 0.0 5.1 4 1 0 4 4 4 2 Myb/SANT-like DNA-binding domain TMA7 PF09072.5 CCC71837.1 - 0.067 13.6 2.1 0.58 10.6 1.5 2.7 1 0 0 1 1 1 0 Translation machinery associated TMA7 MADF_DNA_bdg PF10545.4 CCC71837.1 - 4.3 7.5 18.7 0.17 12.0 2.3 4.1 4 1 1 5 5 5 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Ribosomal_S17 PF00366.15 CCC71838.1 - 1.7e-29 101.6 5.3 2.7e-29 101.0 3.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 DAG_kinase_N PF14513.1 CCC71839.1 - 0.079 13.1 0.3 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus ADH_N PF08240.7 CCC71840.1 - 3.7e-30 103.8 0.3 3.7e-30 103.8 0.2 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 CCC71840.1 - 3.9e-28 97.5 0.7 5.5e-28 97.1 0.5 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCC71840.1 - 6.3e-06 27.1 0.1 1.2e-05 26.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DapB_N PF01113.15 CCC71840.1 - 0.16 11.8 1.8 0.55 10.1 1.2 2.0 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 CCC71841.1 - 9.7e-28 96.3 0.0 1.5e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 CCC71841.1 - 2.9e-12 47.5 0.0 1.1e-11 45.7 0.0 2.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCC71841.1 - 9.4e-11 41.4 0.0 2.4e-10 40.1 0.0 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Cpn60_TCP1 PF00118.19 CCC71843.1 - 7e-11 41.4 0.1 0.00012 20.9 0.0 2.1 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Acyltransferase PF01553.16 CCC71844.1 - 6.6e-29 100.0 0.0 9.8e-29 99.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase AMP-binding PF00501.23 CCC71845.1 - 3.1e-63 213.6 0.0 3.9e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Fig1 PF12351.3 CCC71846.1 - 5.9e-55 185.9 4.7 5.9e-55 185.9 3.2 1.7 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 CCC71846.1 - 0.00081 19.0 17.1 0.0014 18.1 11.8 1.4 1 1 0 1 1 1 1 SUR7/PalI family TOM13 PF08219.6 CCC71846.1 - 0.23 11.2 1.4 0.45 10.3 0.2 2.0 2 0 0 2 2 2 0 Outer membrane protein TOM13 CCSMST1 PF15013.1 CCC71846.1 - 0.24 11.3 0.0 0.24 11.3 0.0 3.1 4 0 0 4 4 4 0 CCSMST1 family DUF3278 PF11683.3 CCC71846.1 - 1.6 8.7 9.1 0.87 9.5 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) DUF912 PF06024.7 CCC71846.1 - 8.2 6.5 6.9 1.6 8.7 0.6 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ATP-synt PF00231.14 CCC71847.1 - 3.7e-68 229.9 2.3 4.2e-68 229.8 1.6 1.0 1 0 0 1 1 1 1 ATP synthase Cache_3 PF14827.1 CCC71847.1 - 0.071 13.0 0.0 0.14 12.0 0.0 1.7 1 1 0 1 1 1 0 Sensory domain of two-component sensor kinase Methyltransf_31 PF13847.1 CCC71848.1 - 7.2e-13 48.3 0.0 1.4e-12 47.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 CCC71848.1 - 4.2e-12 45.7 0.0 7.3e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 CCC71848.1 - 2.3e-11 44.2 0.0 4.1e-10 40.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 CCC71848.1 - 6.2e-11 42.3 0.0 1.7e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 CCC71848.1 - 1.7e-08 34.8 0.0 7.4e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 CCC71848.1 - 1.9e-07 30.6 0.1 3.4e-07 29.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 CCC71848.1 - 1.1e-06 28.4 0.0 2.5e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 CCC71848.1 - 3.4e-06 27.3 0.0 1.3e-05 25.5 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 CCC71848.1 - 8.3e-06 24.7 0.1 1e-05 24.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.15 CCC71848.1 - 9.2e-06 24.9 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.11 CCC71848.1 - 1.2e-05 24.4 0.0 1.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.4 CCC71848.1 - 0.00018 20.9 0.1 0.0003 20.3 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 CCC71848.1 - 0.00056 20.3 0.0 0.0014 19.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 CCC71848.1 - 0.0009 18.8 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.14 CCC71848.1 - 0.0013 18.7 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 CCC71848.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 CCC71848.1 - 0.02 13.9 0.2 0.052 12.6 0.1 1.5 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family UPF0020 PF01170.13 CCC71848.1 - 0.02 14.4 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PCMT PF01135.14 CCC71848.1 - 0.024 14.1 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 CCC71848.1 - 0.067 12.2 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 CCC71848.1 - 0.072 12.3 0.1 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 Cons_hypoth95 PF03602.10 CCC71848.1 - 0.083 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PNPOx_C PF10590.4 CCC71849.1 - 3.2e-21 74.5 2.6 7.8e-21 73.3 1.8 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxidase PF01243.15 CCC71849.1 - 1.1e-11 44.5 0.0 1.7e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxase_2 PF12766.2 CCC71849.1 - 0.047 14.0 0.0 0.083 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase zf-C2H2_4 PF13894.1 CCC71850.1 - 0.00012 22.1 4.3 0.09 13.1 0.1 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger RNA_pol_Rbc25 PF08292.7 CCC71850.1 - 0.038 14.1 0.0 0.14 12.3 0.0 2.0 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 zf-C2H2 PF00096.21 CCC71850.1 - 0.046 14.0 15.2 0.34 11.3 0.3 3.7 3 1 0 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC71850.1 - 0.39 11.1 5.3 0.66 10.3 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double domain Oxysterol_BP PF01237.13 CCC71851.1 - 3.6e-131 436.8 0.0 3.6e-131 436.8 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 CCC71851.1 - 4.6e-15 55.7 2.8 1.9e-07 31.3 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 CCC71851.1 - 6e-13 48.5 5.4 1.3e-05 25.2 0.1 3.8 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 CCC71851.1 - 2.9e-11 42.5 2.4 4.5e-05 23.0 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat PH_8 PF15409.1 CCC71851.1 - 2.4e-10 40.3 0.7 2.4e-10 40.3 0.5 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain Ank_3 PF13606.1 CCC71851.1 - 1e-09 37.6 1.4 0.0066 16.5 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 CCC71851.1 - 2.4e-09 37.4 0.5 0.00017 21.9 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) PH PF00169.24 CCC71851.1 - 7.9e-09 35.6 0.4 7.9e-09 35.6 0.3 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 CCC71851.1 - 0.00031 20.9 3.8 0.00058 20.0 1.1 2.8 2 0 0 2 2 2 1 Pleckstrin homology domain Carn_acyltransf PF00755.15 CCC71852.1 - 1.1e-184 614.8 0.1 1.3e-184 614.6 0.1 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase SAICAR_synt PF01259.13 CCC71853.1 - 7.2e-97 323.3 0.1 8.7e-97 323.1 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase EMP24_GP25L PF01105.19 CCC71854.1 - 7.6e-32 110.5 2.2 9.5e-32 110.1 1.5 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Astacin PF01400.19 CCC71854.1 - 0.024 14.0 3.2 0.032 13.6 2.2 1.2 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Fungal_trans_2 PF11951.3 CCC71854.1 - 0.15 10.6 1.4 0.14 10.7 0.2 1.4 2 0 0 2 2 2 0 Fungal specific transcription factor domain Pkinase PF00069.20 CCC71855.1 - 3.4e-42 144.3 0.0 1.1e-23 83.7 0.0 3.1 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71855.1 - 5.5e-14 51.8 0.0 1.4e-09 37.3 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 CCC71855.1 - 0.011 15.4 0.0 0.025 14.2 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 CCC71855.1 - 0.014 14.4 0.0 5.8 5.7 0.0 2.5 3 0 0 3 3 3 0 Kinase-like DUF4452 PF14618.1 CCC71855.1 - 0.03 14.1 0.1 0.054 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) Steroid_dh PF02544.11 CCC71856.1 - 1.1e-34 119.3 10.1 1.9e-34 118.5 7.0 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Fibrillarin PF01269.12 CCC71857.1 - 1.1e-110 367.9 0.0 1.4e-110 367.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 CCC71857.1 - 2.3e-05 24.0 0.1 4.2e-05 23.1 0.1 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.14 CCC71857.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CYSTM PF12734.2 CCC71858.1 - 3.7e-14 52.5 9.6 3.7e-14 52.5 6.7 4.8 1 1 2 3 3 3 1 Cysteine-rich TM module stress tolerance DUF4106 PF13388.1 CCC71858.1 - 3.6 6.4 17.4 3.6 6.4 12.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF605 PF04652.11 CCC71858.1 - 6.8 5.9 21.9 7.3 5.8 15.1 1.0 1 0 0 1 1 1 0 Vta1 like zf-C3HC4 PF00097.20 CCC71859.1 - 0.0027 17.3 0.1 0.0076 15.8 0.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC71859.1 - 0.0038 16.9 2.2 0.01 15.5 1.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCC71859.1 - 0.0052 16.7 0.1 0.014 15.3 0.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Fer2_3 PF13085.1 CCC71859.1 - 0.028 14.2 0.0 0.067 13.0 0.0 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain zf-RING_2 PF13639.1 CCC71859.1 - 0.049 13.4 0.2 0.12 12.1 0.2 1.7 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 CCC71859.1 - 0.091 12.6 0.2 0.091 12.6 0.1 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING IBR PF01485.16 CCC71859.1 - 0.18 11.7 2.9 3.3 7.6 0.7 2.5 1 1 1 2 2 2 0 IBR domain zf-Apc11 PF12861.2 CCC71860.1 - 6.4e-34 115.6 4.3 8e-34 115.3 3.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 CCC71860.1 - 1.9e-23 82.3 6.9 2.5e-23 81.9 4.8 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 CCC71860.1 - 4.7e-06 26.3 14.8 3.1e-05 23.6 10.3 2.2 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCC71860.1 - 0.0029 17.3 12.2 0.055 13.1 8.7 2.3 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCC71860.1 - 0.0045 16.9 10.0 0.024 14.6 7.0 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 CCC71860.1 - 0.011 15.3 10.6 0.053 13.1 7.4 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H PF13771.1 CCC71860.1 - 0.014 15.4 6.9 0.014 15.4 4.8 2.1 1 1 1 2 2 2 0 PHD-like zinc-binding domain FANCL_C PF11793.3 CCC71860.1 - 0.017 15.0 10.0 0.18 11.7 6.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 CCC71860.1 - 0.044 13.3 1.2 0.044 13.3 0.8 2.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 CCC71860.1 - 0.06 13.0 13.8 1.7 8.3 9.6 2.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CENP-B_dimeris PF09026.5 CCC71860.1 - 0.12 12.6 3.7 0.17 12.1 2.6 1.2 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-RING_6 PF14835.1 CCC71860.1 - 0.16 11.7 6.9 0.2 11.4 4.0 1.7 1 1 1 2 2 2 0 zf-RING of BARD1-type protein PHD PF00628.24 CCC71860.1 - 1 9.0 11.1 3 7.6 7.3 2.1 1 1 0 1 1 1 0 PHD-finger Trm112p PF03966.11 CCC71860.1 - 1.3 9.4 5.2 19 5.6 0.0 2.7 2 1 0 2 2 2 0 Trm112p-like protein zf-RING-like PF08746.6 CCC71860.1 - 1.4 9.0 9.9 5.6 7.0 6.9 2.0 1 1 0 1 1 1 0 RING-like domain zf-HC5HC2H_2 PF13832.1 CCC71860.1 - 1.5 8.8 9.2 0.39 10.7 4.2 1.7 1 1 0 1 1 1 0 PHD-zinc-finger like domain DZR PF12773.2 CCC71860.1 - 3.3 7.5 9.2 2e+02 1.8 6.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon DiS_P_DiS PF06750.8 CCC71860.1 - 6 6.7 6.5 12 5.7 3.8 2.0 1 1 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Tcp11 PF05794.8 CCC71861.1 - 9.3e-121 403.5 5.7 9.3e-121 403.5 4.0 2.5 2 1 0 2 2 2 2 T-complex protein 11 Maf1 PF09174.5 CCC71862.1 - 0.00061 19.6 1.4 0.00079 19.3 0.9 1.2 1 0 0 1 1 1 1 Maf1 regulator CRAM_rpt PF07016.6 CCC71862.1 - 0.073 12.4 3.0 0.073 12.4 2.1 1.9 2 0 0 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor Secretin_N_2 PF07655.8 CCC71862.1 - 7.3 7.0 9.1 44 4.5 5.5 2.0 1 1 1 2 2 2 0 Secretin N-terminal domain Rad51 PF08423.6 CCC71863.1 - 1e-32 113.0 0.0 3.4e-31 108.0 0.0 2.2 2 0 0 2 2 2 1 Rad51 AAA_25 PF13481.1 CCC71863.1 - 1.6e-08 34.1 0.0 2.7e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 CCC71863.1 - 1.6e-05 24.1 0.4 1.6e-05 24.1 0.3 2.4 3 1 0 3 3 3 1 KaiC RecA PF00154.16 CCC71863.1 - 4.1e-05 22.7 0.5 8.5e-05 21.7 0.4 1.4 1 1 0 1 1 1 1 recA bacterial DNA recombination protein RCR PF12273.3 CCC71864.1 - 6.6e-41 139.9 6.5 1.4e-40 138.9 4.5 1.6 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red ATG27 PF09451.5 CCC71864.1 - 0.15 11.2 0.1 0.25 10.5 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 polyprenyl_synt PF00348.12 CCC71865.1 - 3.8e-53 179.9 0.1 9.3e-25 86.9 0.0 3.1 3 0 0 3 3 3 3 Polyprenyl synthetase Cofilin_ADF PF00241.15 CCC71866.1 - 9e-27 93.4 0.2 1.2e-14 54.2 0.0 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF1947 PF09183.5 CCC71866.1 - 0.07 12.8 0.2 0.16 11.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1947) PI3_PI4_kinase PF00454.22 CCC71868.1 - 3.1e-48 164.2 0.8 9.3e-48 162.7 0.5 1.8 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase UME PF08064.8 CCC71868.1 - 1.4e-30 105.4 1.3 4.3e-30 103.8 0.1 2.7 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 CCC71868.1 - 1.9e-13 49.5 0.1 3.8e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 FATC domain FAT PF02259.18 CCC71868.1 - 5.2e-13 48.7 4.3 2.1e-12 46.6 3.0 2.1 1 1 0 1 1 1 1 FAT domain TPR_19 PF14559.1 CCC71868.1 - 0.058 13.7 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat CKS PF01111.14 CCC71869.1 - 2.9e-35 119.9 0.1 4.3e-35 119.3 0.1 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit PRMT5 PF05185.11 CCC71870.1 - 1e-150 502.5 0.2 1.3e-150 502.2 0.1 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 CCC71870.1 - 0.018 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein FCH PF00611.18 CCC71871.1 - 7.1e-15 54.9 4.0 1.1e-14 54.3 0.0 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 CCC71871.1 - 3.2e-09 36.5 1.8 1.7e-08 34.2 0.1 2.5 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 CCC71871.1 - 3e-08 33.2 0.0 8.1e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) CRC_subunit PF08624.5 CCC71872.1 - 7.2e-34 116.6 0.0 1.8e-33 115.4 0.0 1.7 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit NAD_Gly3P_dh_N PF01210.18 CCC71873.1 - 1.4e-52 177.6 0.1 2.1e-52 177.0 0.1 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 CCC71873.1 - 6.2e-49 165.5 0.1 1.4e-48 164.3 0.0 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus F420_oxidored PF03807.12 CCC71873.1 - 0.041 14.3 0.0 8.7 6.8 0.0 2.4 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 CCC71873.1 - 0.072 13.3 0.0 0.26 11.5 0.0 1.9 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.20 CCC71874.1 - 8.9e-59 198.7 1.2 2.7e-58 197.1 0.0 2.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71874.1 - 2.9e-24 85.5 0.0 6.9e-24 84.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC71874.1 - 0.0018 17.2 0.0 0.0033 16.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF2249 PF10006.4 CCC71874.1 - 0.086 12.4 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2249) Pkinase PF00069.20 CCC71876.1 - 9.6e-53 178.9 0.0 1.8e-52 178.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71876.1 - 6.1e-25 87.7 0.0 1.2e-24 86.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 CCC71876.1 - 0.0018 18.0 0.0 1.1 8.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 CCC71876.1 - 0.0059 15.6 0.1 0.033 13.2 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 CCC71876.1 - 0.0061 15.5 0.0 0.016 14.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Alpha-amylase PF00128.19 CCC71876.1 - 9.4 5.5 12.3 0.15 11.4 3.0 2.0 3 0 0 3 3 3 0 Alpha amylase, catalytic domain tRNA-synt_2 PF00152.15 CCC71877.1 - 4.6e-76 255.7 1.0 6.7e-76 255.2 0.1 1.6 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 CCC71877.1 - 1e-07 31.3 0.9 5.9e-05 22.3 0.1 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 CCC71877.1 - 3e-07 30.1 0.0 6.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 CCC71877.1 - 0.018 14.6 0.1 3.4 7.2 0.0 2.5 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_anti-like PF12869.2 CCC71877.1 - 0.028 13.8 0.1 0.052 13.0 0.1 1.3 1 0 0 1 1 1 0 tRNA_anti-like tRNA_Me_trans PF03054.11 CCC71878.1 - 1.7e-115 385.3 0.0 2e-115 385.1 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 CCC71878.1 - 1.2e-05 24.9 0.0 5.1e-05 22.8 0.0 1.9 2 0 0 2 2 2 1 Asparagine synthase NAD_synthase PF02540.12 CCC71878.1 - 0.00029 19.8 0.0 0.043 12.7 0.0 2.6 2 1 0 2 2 2 2 NAD synthase ThiI PF02568.9 CCC71878.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Git3 PF11710.3 CCC71879.1 - 1e-76 257.0 11.4 1.8e-76 256.2 7.9 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 CCC71879.1 - 1.6e-28 98.2 3.0 5.3e-28 96.5 2.1 2.0 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term PseudoU_synth_2 PF00849.17 CCC71880.1 - 5.8e-34 117.2 0.5 1.2e-33 116.2 0.0 1.7 2 0 0 2 2 2 1 RNA pseudouridylate synthase dCMP_cyt_deam_1 PF00383.17 CCC71880.1 - 4.3e-19 68.0 0.0 7.3e-19 67.3 0.0 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region NARP1 PF12569.3 CCC71881.1 - 1.8e-110 370.1 25.6 4.4e-81 273.1 2.7 3.0 3 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_16 PF13432.1 CCC71881.1 - 2.3e-15 56.7 7.3 0.00076 20.0 0.0 6.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 CCC71881.1 - 1.4e-11 43.3 7.7 0.019 14.8 0.0 7.3 9 0 0 9 9 7 4 Tetratricopeptide repeat TPR_19 PF14559.1 CCC71881.1 - 4.2e-11 43.0 7.5 0.026 14.8 0.0 6.3 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 CCC71881.1 - 3.2e-10 39.6 3.2 0.72 10.6 0.0 7.6 7 2 1 8 8 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 CCC71881.1 - 2.2e-09 36.8 20.4 0.0095 15.5 0.0 5.3 7 0 0 7 7 7 4 TPR repeat TPR_17 PF13431.1 CCC71881.1 - 1.4e-06 27.9 10.9 1.1 9.6 0.0 6.7 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 CCC71881.1 - 2.5e-06 26.8 6.2 0.32 10.6 0.0 7.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.1 CCC71881.1 - 3.2e-06 26.9 13.7 0.0048 16.8 0.0 6.1 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 CCC71881.1 - 5.8e-06 26.3 11.4 0.0025 17.9 0.5 4.8 4 1 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 CCC71881.1 - 0.0012 18.4 22.0 0.088 12.6 0.0 7.6 10 0 0 10 10 9 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 CCC71881.1 - 0.0034 17.2 4.5 0.062 13.1 0.1 4.0 4 1 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat HLH PF00010.21 CCC71882.1 - 9.9e-18 63.5 0.0 3.9e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain DUF904 PF06005.7 CCC71882.1 - 0.063 13.5 1.3 0.43 10.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF592 PF04574.8 CCC71883.1 - 1.8e-65 219.1 1.7 3.7e-65 218.1 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF592) SIR2 PF02146.12 CCC71883.1 - 1.9e-64 216.6 0.0 3e-64 216.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 CCC71883.1 - 0.00053 19.7 0.0 0.39 10.4 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Aldo_ket_red PF00248.16 CCC71884.1 - 1.5e-63 214.3 0.1 1.6e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CNPase PF05881.7 CCC71884.1 - 0.022 14.1 0.1 0.047 13.0 0.0 1.5 1 1 0 1 1 1 0 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) zf-met PF12874.2 CCC71885.1 - 1.7e-06 28.0 1.4 3.3e-06 27.0 0.9 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-U1 PF06220.7 CCC71885.1 - 0.0096 15.4 0.1 0.017 14.6 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_2 PF12756.2 CCC71885.1 - 0.032 14.3 0.2 0.061 13.4 0.1 1.5 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) RasGAP_C PF03836.10 CCC71886.1 - 0.24 11.1 6.2 0.11 12.1 0.8 2.3 2 0 0 2 2 2 0 RasGAP C-terminus PAPS_reduct PF01507.14 CCC71887.1 - 1.6e-35 122.4 0.0 2.1e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family CHCH PF06747.8 CCC71888.1 - 1.2e-05 25.0 0.5 1.7e-05 24.6 0.3 1.2 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.5 CCC71888.1 - 0.0006 19.5 1.5 0.0007 19.3 1.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like E1_DerP2_DerF2 PF02221.10 CCC71889.1 - 5.4e-24 84.9 0.0 6.2e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 CCC71889.1 - 0.00013 21.9 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 ML-like domain Metallophos PF00149.23 CCC71890.1 - 1.1e-42 145.7 0.1 1.4e-42 145.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCC71890.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DIL PF01843.14 CCC71890.1 - 0.096 12.5 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 DIL domain Prefoldin PF02996.12 CCC71892.1 - 5.2e-36 122.9 0.8 7.3e-36 122.4 0.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 CCC71892.1 - 0.0011 18.6 3.0 0.0041 16.8 0.4 2.3 1 1 1 2 2 2 1 Prefoldin subunit DUF1664 PF07889.7 CCC71892.1 - 0.057 13.2 0.4 2.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4476 PF14771.1 CCC71892.1 - 0.075 13.0 0.5 0.24 11.4 0.1 2.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4476) HCR PF07111.7 CCC71892.1 - 0.08 10.9 2.4 0.099 10.6 0.7 1.6 2 0 0 2 2 2 0 Alpha helical coiled-coil rod protein (HCR) CENP-F_leu_zip PF10473.4 CCC71892.1 - 0.14 12.0 6.4 0.48 10.2 1.6 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SUN PF03856.8 CCC71893.1 - 1.9e-79 266.5 19.6 2.3e-79 266.2 13.6 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) DUF336 PF03928.9 CCC71894.1 - 3.3e-24 85.1 0.0 3.8e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF336) Cag12 PF13117.1 CCC71895.1 - 1.8 8.4 5.8 0.79 9.6 0.7 2.4 2 0 0 2 2 2 0 Cag pathogenicity island protein Cag12 NatB_MDM20 PF09797.4 CCC71896.1 - 9.3e-61 205.5 10.8 9.3e-61 205.5 7.5 2.0 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit YopX PF09643.5 CCC71896.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.6 3 0 0 3 3 3 0 YopX protein Peptidase_S10 PF00450.17 CCC71897.1 - 3e-127 425.2 0.4 3.7e-127 424.9 0.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 CCC71897.1 - 0.00012 22.0 0.0 0.00035 20.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family RasGAP PF00616.14 CCC71898.1 - 1.4e-33 116.2 0.8 5.6e-33 114.2 0.1 2.5 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase DUF3321 PF11968.3 CCC71899.1 - 2.7e-81 272.4 0.3 4.2e-81 271.7 0.2 1.3 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 CCC71899.1 - 0.00019 21.1 0.0 0.00034 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 CCC71899.1 - 0.0038 16.8 0.0 0.0064 16.1 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 CCC71899.1 - 0.0093 16.4 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 CCC71899.1 - 0.066 13.6 0.0 0.19 12.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain DEAD PF00270.24 CCC71900.1 - 4.9e-38 130.2 0.1 1e-37 129.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC71900.1 - 2.5e-25 88.1 0.8 6e-23 80.4 0.0 3.0 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 CCC71900.1 - 0.00011 22.0 0.3 0.00011 22.0 0.2 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit eRF1_2 PF03464.10 CCC71901.1 - 2.5e-45 154.0 0.0 4.7e-45 153.1 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 CCC71901.1 - 7.8e-37 126.0 0.5 1.6e-36 124.9 0.3 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 CCC71901.1 - 1e-29 102.7 0.0 2e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 DUF1877 PF08974.5 CCC71902.1 - 0.00011 21.9 0.8 0.0002 21.0 0.2 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF1877) TLV_coat PF00429.14 CCC71902.1 - 0.12 10.8 1.0 0.2 10.0 0.7 1.3 1 0 0 1 1 1 0 ENV polyprotein (coat polyprotein) ADH_zinc_N PF00107.21 CCC71903.1 - 5e-32 110.1 1.7 7.4e-32 109.6 1.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCC71903.1 - 5.7e-31 106.4 0.3 1.3e-30 105.3 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CCC71903.1 - 1.7e-05 25.6 0.1 4.4e-05 24.3 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase DapB_N PF01113.15 CCC71903.1 - 0.003 17.4 1.7 0.0059 16.5 1.2 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus YbjQ_1 PF01906.12 CCC71903.1 - 0.019 15.3 0.6 0.056 13.8 0.1 2.0 2 0 0 2 2 2 0 Putative heavy-metal-binding Ribosomal_S9 PF00380.14 CCC71904.1 - 1.1e-36 125.7 0.1 2e-36 124.8 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 RNA_pol_Rpb5_C PF01191.14 CCC71905.1 - 1.3e-33 114.3 0.5 2.4e-33 113.5 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 CCC71905.1 - 3e-33 114.1 0.6 5.6e-33 113.2 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Sof1 PF04158.9 CCC71905.1 - 0.062 13.3 0.2 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 Sof1-like domain Mrr_cat PF04471.7 CCC71905.1 - 0.064 13.0 0.0 0.21 11.4 0.0 1.8 2 0 0 2 2 2 0 Restriction endonuclease RibD_C PF01872.12 CCC71906.1 - 1.8e-36 125.6 0.0 2.1e-36 125.4 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain DUF3897 PF13036.1 CCC71906.1 - 0.043 13.4 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3897) Suc_Fer-like PF06999.7 CCC71908.1 - 2.9e-58 197.6 0.0 4.6e-58 196.9 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Phospholip_A2_3 PF09056.6 CCC71908.1 - 0.086 13.0 1.0 0.44 10.7 0.1 2.2 2 0 0 2 2 2 0 Prokaryotic phospholipase A2 Fungal_trans PF04082.13 CCC71909.1 - 2.5e-11 42.9 5.5 5.6e-11 41.8 3.8 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 CCC71909.1 - 2.3e-08 33.8 8.3 4.2e-08 32.9 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 CCC71910.1 - 1.8e-44 151.6 0.0 2.3e-44 151.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family PQ-loop PF04193.9 CCC71912.1 - 3.5e-39 132.1 19.1 1.2e-20 72.8 2.2 3.1 3 0 0 3 3 3 2 PQ loop repeat Vps52 PF04129.7 CCC71913.1 - 1.1e-137 459.6 28.6 1.5e-137 459.2 19.8 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family YL1 PF05764.8 CCC71914.1 - 1.3e-53 182.0 59.2 1.3e-53 182.0 41.0 3.0 2 1 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.6 CCC71914.1 - 8.7e-13 47.5 0.3 1.5e-12 46.8 0.2 1.4 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Snf7 PF03357.16 CCC71915.1 - 6e-38 129.9 15.9 7.2e-38 129.6 11.0 1.1 1 0 0 1 1 1 1 Snf7 YlqD PF11068.3 CCC71915.1 - 0.002 18.1 9.9 0.002 18.1 6.8 2.2 1 1 1 2 2 2 1 YlqD protein SMC_Nse1 PF07574.8 CCC71915.1 - 0.0021 17.6 1.7 0.0029 17.2 1.2 1.2 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex Exonuc_VII_L PF02601.10 CCC71915.1 - 0.015 14.4 7.5 0.018 14.2 5.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mnd1 PF03962.10 CCC71915.1 - 0.034 13.8 12.3 0.061 12.9 3.1 2.1 1 1 1 2 2 2 0 Mnd1 family AIP3 PF03915.8 CCC71915.1 - 0.042 12.7 14.8 0.06 12.2 10.2 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 Fmp27_WPPW PF10359.4 CCC71915.1 - 0.066 11.6 10.2 0.085 11.2 6.6 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain BLOC1_2 PF10046.4 CCC71915.1 - 0.082 13.0 17.5 0.26 11.4 3.1 2.8 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Ribosomal_L29 PF00831.18 CCC71915.1 - 0.64 9.7 8.0 4.5 7.0 0.1 3.6 3 1 1 4 4 4 0 Ribosomal L29 protein Tweety PF04906.8 CCC71915.1 - 0.78 8.0 10.3 2.5 6.4 0.9 2.0 1 1 1 2 2 2 0 Tweety Reo_sigmaC PF04582.7 CCC71915.1 - 0.79 8.8 9.0 1.3 8.1 5.7 1.7 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Cep57_MT_bd PF06657.8 CCC71915.1 - 0.84 9.6 12.9 0.038 13.9 2.3 2.7 1 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 FlaC_arch PF05377.6 CCC71915.1 - 1.5 8.8 5.4 6.5 6.7 0.1 3.5 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Serine_rich PF08824.5 CCC71915.1 - 1.8 8.2 13.7 1 9.0 6.3 2.5 1 1 1 2 2 2 0 Serine rich protein interaction domain Atg14 PF10186.4 CCC71915.1 - 2.2 7.1 14.0 3.1 6.6 9.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin_1 PF12718.2 CCC71915.1 - 2.6 7.8 16.3 0.45 10.3 7.7 2.1 1 1 1 2 2 2 0 Tropomyosin like DUF342 PF03961.8 CCC71915.1 - 3.4 5.9 9.6 6.9 4.9 6.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF342) DUF1664 PF07889.7 CCC71915.1 - 4.1 7.2 11.0 1.2 8.9 1.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DHBP_synthase PF00926.14 CCC71916.1 - 1.7e-80 268.8 0.1 1.9e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase WD40 PF00400.27 CCC71917.1 - 3.2e-06 26.8 4.3 2e-05 24.2 1.0 3.5 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF740 PF05340.7 CCC71917.1 - 0.28 9.4 4.0 0.4 8.9 2.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Sld5 PF05916.6 CCC71918.1 - 5e-17 62.1 0.1 1.3e-16 60.8 0.1 1.7 1 0 0 1 1 1 1 GINS complex protein CPL PF08144.6 CCC71919.1 - 2.2e-17 63.2 0.1 1.1e-15 57.7 0.0 3.1 3 0 0 3 3 3 1 CPL (NUC119) domain PUF PF00806.14 CCC71919.1 - 2.9e-05 23.2 4.3 0.63 9.6 0.0 5.1 6 0 0 6 6 6 2 Pumilio-family RNA binding repeat DUF4253 PF14062.1 CCC71919.1 - 0.087 12.4 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4253) Daxx PF03344.10 CCC71919.1 - 0.39 9.1 14.2 0.59 8.5 9.8 1.2 1 0 0 1 1 1 0 Daxx Family Sugar_tr PF00083.19 CCC71920.1 - 1.8e-144 481.7 31.7 2.1e-144 481.4 22.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC71920.1 - 1.3e-31 109.6 36.4 6.4e-31 107.3 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCC71920.1 - 2.6e-07 29.2 2.1 2.6e-07 29.2 1.4 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 CCC71920.1 - 0.00082 17.6 0.4 0.00082 17.6 0.3 1.7 2 0 0 2 2 2 1 Transmembrane secretion effector DUF1279 PF06916.8 CCC71920.1 - 0.051 13.8 0.7 0.28 11.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1279) Med1 PF10744.4 CCC71920.1 - 0.31 9.7 1.8 0.57 8.8 1.3 1.3 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription subunit 1 Sec20 PF03908.8 CCC71921.1 - 2.5e-27 94.4 0.5 2.5e-27 94.4 0.3 2.2 3 0 0 3 3 3 1 Sec20 Vps39_2 PF10367.4 CCC71922.1 - 0.25 11.5 4.9 1.1 9.4 0.2 3.4 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 HlyIII PF03006.15 CCC71925.1 - 1.7e-48 164.9 28.4 2e-48 164.7 19.7 1.0 1 0 0 1 1 1 1 Haemolysin-III related ERG4_ERG24 PF01222.12 CCC71926.1 - 4.1e-165 549.5 16.0 4.6e-165 549.3 11.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 CCC71926.1 - 2.2e-06 27.1 1.3 2.2e-06 27.1 0.9 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) PDR_CDR PF06422.7 CCC71926.1 - 0.057 13.0 1.2 2.6 7.7 0.1 2.4 2 0 0 2 2 2 0 CDR ABC transporter DUF3542 PF12061.3 CCC71928.1 - 0.036 13.0 0.0 0.51 9.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3542) DUF4231 PF14015.1 CCC71928.1 - 0.039 13.9 0.0 0.076 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) 6PGD PF00393.14 CCC71928.1 - 0.11 11.6 0.0 0.15 11.2 0.0 1.1 1 0 0 1 1 1 0 6-phosphogluconate dehydrogenase, C-terminal domain Aha1_N PF09229.6 CCC71929.1 - 2.7e-30 104.9 4.4 3.2e-30 104.7 3.1 1.0 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal RNase_P_pop3 PF08228.6 CCC71930.1 - 3.8e-42 143.7 2.8 4.7e-42 143.5 1.9 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 WSC PF01822.14 CCC71931.1 - 4.8e-14 52.0 16.8 4.8e-14 52.0 11.7 3.1 3 1 0 3 3 3 1 WSC domain SKG6 PF08693.5 CCC71931.1 - 0.0022 17.2 2.1 0.0022 17.2 1.5 3.3 3 1 1 4 4 4 1 Transmembrane alpha-helix domain DUF2668 PF10873.3 CCC71931.1 - 0.0056 16.8 0.9 0.0056 16.8 0.6 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2668) Syndecan PF01034.15 CCC71931.1 - 0.007 16.0 0.1 0.017 14.7 0.1 1.6 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.1 CCC71931.1 - 0.0097 16.2 0.0 0.046 14.1 0.0 2.2 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF912 PF06024.7 CCC71931.1 - 0.028 14.4 0.1 0.028 14.4 0.1 3.3 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Adeno_E3_CR2 PF02439.10 CCC71931.1 - 0.9 9.1 5.2 2 8.0 3.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 GFA PF04828.9 CCC71932.1 - 0.0079 16.1 0.3 0.014 15.3 0.2 1.4 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.5 CCC71932.1 - 0.25 10.8 3.9 0.56 9.7 2.7 1.6 1 0 0 1 1 1 0 A2L zinc ribbon domain DUF2638 PF10937.3 CCC71933.1 - 0.08 13.9 0.2 0.15 13.0 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2638) PAP2 PF01569.16 CCC71934.1 - 4e-13 49.1 3.5 1.2e-12 47.5 2.4 1.8 1 0 0 1 1 1 1 PAP2 superfamily Ribosomal_S21e PF01249.13 CCC71935.1 - 4.6e-39 132.2 0.0 5.1e-39 132.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Pkinase PF00069.20 CCC71936.1 - 1.2e-53 181.9 0.1 1.2e-52 178.6 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71936.1 - 1.6e-20 73.3 0.0 3e-20 72.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 CCC71936.1 - 0.0035 16.7 0.4 0.012 14.9 0.0 2.0 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 CCC71936.1 - 0.031 14.0 0.1 0.069 12.8 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Tim17 PF02466.14 CCC71937.1 - 2e-33 115.1 3.6 2.3e-33 114.9 2.5 1.0 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CRAL_TRIO PF00650.15 CCC71939.1 - 5.3e-28 97.5 1.1 9.4e-28 96.6 0.7 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCC71939.1 - 6.4e-05 23.0 0.0 0.00017 21.6 0.0 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain DUF948 PF06103.6 CCC71941.1 - 0.032 14.0 2.7 0.67 9.8 0.5 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ATP-synt_E_2 PF08112.6 CCC71941.1 - 0.86 9.7 10.9 2.1 8.4 0.0 3.3 4 0 0 4 4 4 0 ATP synthase epsilon subunit F-box-like PF12937.2 CCC71942.1 - 5.9e-09 35.5 0.1 2.4e-08 33.5 0.1 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 CCC71942.1 - 2.2e-07 30.3 0.3 1.2e-05 24.7 0.0 2.9 2 0 0 2 2 2 1 F-box domain NAD_binding_5 PF07994.7 CCC71943.1 - 7.2e-113 376.9 0.1 8.8e-113 376.6 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 CCC71943.1 - 2e-43 146.7 0.2 4.6e-43 145.6 0.2 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Vps35 PF03635.12 CCC71944.1 - 5.3e-182 606.8 39.1 6.5e-182 606.5 27.1 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 6PF2K PF01591.13 CCC71945.1 - 1.5e-77 259.6 3.2 2.3e-77 259.0 2.2 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 CCC71945.1 - 4.3e-32 111.3 0.0 8.4e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 CCC71945.1 - 0.00021 22.0 0.0 0.0023 18.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 CCC71945.1 - 0.00039 20.3 0.0 0.00071 19.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain Peptidase_S64 PF08192.6 CCC71946.1 - 5.1e-238 791.9 6.5 5.8e-238 791.7 4.5 1.0 1 0 0 1 1 1 1 Peptidase family S64 CLAMP PF14769.1 CCC71946.1 - 0.01 15.9 2.3 0.052 13.7 0.4 2.5 2 0 0 2 2 2 0 Flagellar C1a complex subunit C1a-32 zf-RING_2 PF13639.1 CCC71947.1 - 0.00043 20.0 4.0 0.0015 18.3 2.8 2.0 1 0 0 1 1 1 1 Ring finger domain DUF4182 PF13790.1 CCC71947.1 - 0.066 13.0 1.0 56 3.6 0.5 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4182) zf-RING_5 PF14634.1 CCC71947.1 - 0.56 9.9 4.0 1.2 8.8 2.8 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 CCC71947.1 - 0.98 9.1 4.2 2.8 7.6 2.9 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 CCC71947.1 - 1 9.1 4.3 20 5.0 0.3 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PIR PF00399.14 CCC71948.1 - 3.3e-06 26.2 1.9 3.3e-06 26.2 1.3 2.8 3 0 0 3 3 3 1 Yeast PIR protein repeat SprB PF13573.1 CCC71948.1 - 0.14 11.7 2.7 0.32 10.6 0.3 2.6 2 0 0 2 2 2 0 SprB repeat PIR PF00399.14 CCC71949.1 - 8.7e-51 167.6 101.2 1.4e-08 33.7 4.4 8.1 7 0 0 7 7 7 7 Yeast PIR protein repeat DUF2072 PF09845.4 CCC71949.1 - 0.15 11.9 0.9 0.68 9.8 0.6 2.1 1 1 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) PP2C_2 PF13672.1 CCC71949.1 - 0.61 9.4 15.3 18 4.6 9.1 2.9 2 1 1 3 3 3 0 Protein phosphatase 2C vWA-TerF-like PF10138.4 CCC71949.1 - 2.2 8.0 9.6 13 5.5 1.3 3.1 1 1 1 2 2 2 0 vWA found in TerF C terminus AKAP2_C PF15304.1 CCC71949.1 - 8.1 5.9 13.1 11 5.4 9.1 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus DUF3536 PF12055.3 CCC71949.1 - 10 5.2 9.5 23 4.0 5.2 2.2 1 1 2 3 3 3 0 Domain of unknown function (DUF3536) PIR PF00399.14 CCC71950.1 - 2e-08 33.2 9.7 6e-06 25.4 1.5 2.9 2 0 0 2 2 2 2 Yeast PIR protein repeat Elf1 PF05129.8 CCC71950.1 - 0.00018 21.0 0.9 0.00035 20.2 0.6 1.4 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like CDP-OH_P_tran_2 PF08009.6 CCC71950.1 - 0.11 12.2 0.8 0.18 11.5 0.5 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 Serinc PF03348.10 CCC71950.1 - 0.26 9.9 1.7 0.34 9.5 1.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) YfhO PF09586.5 CCC71950.1 - 1.3 7.0 10.7 0.39 8.6 5.8 1.3 2 0 0 2 2 2 0 Bacterial membrane protein YfhO Herpes_UL3 PF03369.8 CCC71950.1 - 3.3 7.6 7.5 2.3 8.2 3.4 1.8 1 1 1 2 2 2 0 Herpesvirus UL3 protein DnaJ PF00226.26 CCC71951.1 - 1.9e-20 72.3 0.5 6.2e-20 70.6 0.3 2.0 1 0 0 1 1 1 1 DnaJ domain Pkinase PF00069.20 CCC71952.1 - 9.3e-71 238.0 0.0 1.1e-70 237.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71952.1 - 3.5e-40 137.7 0.0 4.7e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC71952.1 - 2e-05 23.7 0.0 3.5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 CCC71952.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.1 CCC71952.1 - 0.1 12.2 0.1 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.9 CCC71952.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 CCC71953.1 - 7.8e-51 172.7 0.0 1.4e-50 171.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71953.1 - 2.3e-18 66.2 0.0 4.3e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 CCC71953.1 - 0.017 14.1 0.1 0.04 12.9 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DHC PF09626.5 CCC71953.1 - 0.051 14.2 2.3 2.3 8.9 0.1 3.0 2 1 1 3 3 3 0 Dihaem cytochrome c Kinase-like PF14531.1 CCC71953.1 - 0.072 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 CCC71953.1 - 0.12 12.0 0.1 0.2 11.3 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family UcrQ PF02939.11 CCC71954.1 - 1.7e-37 127.1 2.1 1.9e-37 126.9 1.4 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 CCC71954.1 - 0.028 14.5 0.0 0.036 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2741) Ebp2 PF05890.7 CCC71955.1 - 2.1e-86 289.5 27.4 2.1e-86 289.5 19.0 3.0 1 1 1 2 2 2 1 Eukaryotic rRNA processing protein EBP2 SRI PF08236.6 CCC71956.1 - 3.7e-24 84.4 8.6 2.3e-23 81.9 6.0 2.5 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 CCC71956.1 - 1.2e-22 80.9 0.6 1.2e-22 80.9 0.4 4.0 3 2 0 3 3 3 1 SET domain Prok-E2_B PF14461.1 CCC71956.1 - 0.16 11.6 0.1 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 Prokaryotic E2 family B Rhabdo_glycop PF00974.13 CCC71957.1 - 0.0042 15.3 0.2 0.0054 15.0 0.1 1.1 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein Peptidase_M20 PF01546.23 CCC71958.1 - 3.1e-24 85.5 0.0 4.5e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 CCC71958.1 - 5.4e-17 61.5 0.0 4.2e-16 58.6 0.0 2.1 1 1 0 1 1 1 1 Peptidase dimerisation domain Rep_fac-A_3 PF08661.6 CCC71959.1 - 9.3e-21 73.7 0.0 1.1e-20 73.5 0.0 1.1 1 0 0 1 1 1 1 Replication factor A protein 3 KRE9 PF05390.6 CCC71960.1 - 1.6e-50 169.9 8.9 1.6e-50 169.9 6.2 2.4 3 0 0 3 3 3 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CCC71960.1 - 5.6e-10 39.5 4.5 5.6e-10 39.5 3.1 2.9 2 2 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CLPTM1 PF05602.7 CCC71960.1 - 0.0067 15.2 0.0 0.012 14.4 0.0 1.4 1 1 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) SWIRM PF04433.12 CCC71961.1 - 3.9e-32 110.2 0.3 2.1e-31 107.8 0.2 2.4 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-bind_6 PF13921.1 CCC71961.1 - 5.1e-10 39.2 0.1 3.4e-09 36.6 0.1 2.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 CCC71961.1 - 7.6e-09 35.4 0.0 2.1e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribosomal_L22 PF00237.14 CCC71962.1 - 9.5e-34 115.5 0.2 9.5e-34 115.5 0.1 1.4 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e CRT10 PF08728.5 CCC71962.1 - 0.14 10.1 0.2 0.15 10.0 0.1 1.0 1 0 0 1 1 1 0 CRT10 ATG27 PF09451.5 CCC71963.1 - 2.8e-66 223.5 0.6 3.4e-66 223.2 0.4 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 PBP1_TM PF14812.1 CCC71963.1 - 0.065 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Prefoldin_2 PF01920.15 CCC71964.1 - 1.4e-13 50.4 7.2 1.6e-13 50.3 5.0 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF4502 PF14950.1 CCC71964.1 - 0.0012 18.1 0.2 0.0013 17.9 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) RimK PF08443.6 CCC71964.1 - 0.056 12.9 0.3 0.06 12.8 0.2 1.1 1 0 0 1 1 1 0 RimK-like ATP-grasp domain CST-I PF06002.7 CCC71964.1 - 0.069 12.4 0.2 0.071 12.3 0.2 1.1 1 0 0 1 1 1 0 Alpha-2,3-sialyltransferase (CST-I) Mut7-C PF01927.11 CCC71964.1 - 0.21 11.5 2.0 4.4 7.2 0.0 2.1 1 1 1 2 2 2 0 Mut7-C RNAse domain DUF948 PF06103.6 CCC71964.1 - 0.54 10.1 5.4 2.6 7.9 0.2 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CCDC-167 PF15188.1 CCC71964.1 - 0.85 9.6 5.8 0.34 10.8 1.1 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 IncA PF04156.9 CCC71964.1 - 7.4 6.1 9.8 1.8 8.0 2.2 2.0 2 0 0 2 2 2 0 IncA protein ATP12 PF07542.6 CCC71965.1 - 8e-31 106.5 0.1 1.6e-29 102.3 0.0 2.1 2 0 0 2 2 2 1 ATP12 chaperone protein Glyco_transf_34 PF05637.7 CCC71966.1 - 4.2e-53 180.3 0.1 6.4e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF746 PF05344.6 CCC71966.1 - 0.11 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF746) Gon7 PF08738.5 CCC71967.1 - 9.1e-32 109.1 0.2 1.2e-31 108.7 0.2 1.2 1 0 0 1 1 1 1 Gon7 family Paxillin PF03535.8 CCC71967.1 - 0.056 13.2 0.0 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Paxillin family RXT2_N PF08595.6 CCC71968.1 - 4.3 7.1 8.0 9.2 6.0 5.3 1.7 1 1 1 2 2 2 0 RXT2-like, N-terminal muHD PF10291.4 CCC71969.1 - 5.7e-73 245.2 0.0 1.6e-72 243.8 0.0 1.8 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 CCC71969.1 - 0.0036 17.4 1.1 0.0036 17.4 0.7 2.7 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Pkinase PF00069.20 CCC71970.1 - 1.2e-46 158.9 0.1 2.3e-46 158.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC71970.1 - 2.3e-27 95.7 0.0 3.6e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 CCC71970.1 - 0.05 12.5 0.0 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 Kinase-like Ribosomal_L39 PF00832.15 CCC71972.1 - 1.5e-23 82.0 11.2 1.7e-23 81.7 7.8 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Gas_vesicle_C PF01304.12 CCC71972.1 - 0.067 12.8 1.4 0.099 12.2 1.0 1.2 1 0 0 1 1 1 0 Gas vesicles protein GVPc repeated domain Ribosomal_S8 PF00410.14 CCC71973.1 - 1e-26 93.2 0.1 1.4e-26 92.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S11 PF00411.14 CCC71974.1 - 2.4e-40 137.0 0.8 2.9e-40 136.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Op_neuropeptide PF08035.6 CCC71975.1 - 0.027 14.0 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 Opioids neuropeptide TPT PF03151.11 CCC71978.1 - 2.7e-38 131.0 2.2 2.7e-38 131.0 1.5 2.9 2 1 2 4 4 4 1 Triose-phosphate Transporter family EamA PF00892.15 CCC71978.1 - 0.00048 20.1 34.3 0.039 14.0 9.8 3.4 3 2 0 3 3 3 2 EamA-like transporter family UAA PF08449.6 CCC71978.1 - 0.00073 18.5 4.0 0.00073 18.5 2.7 2.1 2 0 0 2 2 2 1 UAA transporter family AAA PF00004.24 CCC71979.1 - 4.7e-10 39.7 0.1 2.2e-09 37.6 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCC71979.1 - 8.8e-10 38.8 0.0 4.7e-09 36.4 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 CCC71979.1 - 2.1e-07 31.1 0.0 7.7e-06 26.0 0.0 2.5 1 1 0 1 1 1 1 AAA ATPase domain Cdc6_C PF09079.6 CCC71979.1 - 0.00011 21.8 0.0 0.00029 20.4 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal AAA_19 PF13245.1 CCC71979.1 - 0.00016 21.3 0.1 0.0017 18.0 0.0 2.5 3 0 0 3 3 3 1 Part of AAA domain AAA_29 PF13555.1 CCC71979.1 - 0.029 13.8 0.3 0.16 11.5 0.0 2.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_11 PF13086.1 CCC71979.1 - 0.053 13.1 0.4 1.2 8.6 0.0 2.9 4 0 0 4 4 4 0 AAA domain AAA_5 PF07728.9 CCC71979.1 - 0.092 12.4 0.0 2 8.1 0.0 2.6 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Myb_DNA-binding PF00249.26 CCC71980.1 - 0.00012 22.0 0.0 0.00042 20.3 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain ELO PF01151.13 CCC71981.1 - 1.1e-61 208.2 26.0 1.4e-61 207.9 18.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family FixQ PF05545.6 CCC71981.1 - 5.1 6.8 10.3 0.36 10.4 0.1 3.5 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ UCH PF00443.24 CCC71982.1 - 4.6e-89 298.0 4.2 2.9e-48 164.3 0.2 2.6 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 CCC71982.1 - 4.8e-20 72.1 7.2 1.8e-11 44.0 0.0 3.0 3 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 CCC71982.1 - 1e-05 25.8 0.1 1e-05 25.8 0.1 3.2 3 1 0 3 3 3 1 DUSP domain SPX PF03105.14 CCC71983.1 - 3.6e-47 161.4 13.6 5.7e-47 160.7 9.4 1.3 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 CCC71983.1 - 1.1e-15 57.5 40.4 1.5e-15 57.0 28.0 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 CCC71983.1 - 1.1e-14 53.7 45.7 2.4e-13 49.3 17.7 2.1 1 1 1 2 2 2 2 Citrate transporter ATPase_gene1 PF09527.5 CCC71983.1 - 5.4 6.8 15.8 0.25 11.1 3.6 3.8 3 0 0 3 3 3 0 Putative F0F1-ATPase subunit (ATPase_gene1) Sugar_tr PF00083.19 CCC71984.1 - 6.2e-160 532.6 36.4 7.2e-160 532.4 25.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC71984.1 - 2e-30 105.7 36.3 1.2e-26 93.2 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 CCC71984.1 - 0.0011 17.1 3.4 0.0011 17.1 2.4 1.6 2 0 0 2 2 2 1 Transmembrane secretion effector Flo11 PF10182.4 CCC71986.1 - 1.6e-45 154.4 1.7 1.6e-45 154.4 1.2 2.9 3 1 0 3 3 3 1 Flo11 domain Sugar_tr PF00083.19 CCC71989.1 - 3e-168 560.0 32.7 3.5e-168 559.8 22.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC71989.1 - 6.3e-27 94.2 27.1 1.3e-26 93.1 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 CCC71989.1 - 0.84 8.0 26.8 0.1 11.0 6.5 3.0 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like DUF3589 PF12141.3 CCC71990.1 - 5.8e-101 338.1 0.3 3e-58 197.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3589) GST_N_2 PF13409.1 CCC71991.1 - 4.3e-15 55.4 1.0 3.2e-14 52.6 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 CCC71991.1 - 2.7e-06 27.1 0.0 5.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 CCC71991.1 - 0.012 15.7 0.0 0.076 13.2 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Sugar_tr PF00083.19 CCC71992.1 - 1.4e-168 561.2 33.7 1.6e-168 560.9 23.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC71992.1 - 2.9e-27 95.3 27.7 1e-26 93.5 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 CCC71992.1 - 4.7 5.5 27.9 0.19 10.1 7.5 2.9 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like AA_permease PF00324.16 CCC71994.1 - 6.8e-114 380.8 34.4 7.7e-114 380.6 23.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 CCC71994.1 - 6.6e-37 127.0 41.4 8e-37 126.7 28.7 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2637 PF10935.3 CCC71994.1 - 0.046 13.6 3.6 0.14 12.1 2.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2637) Lactamase_B_2 PF12706.2 CCC71995.1 - 1.1e-20 74.0 0.0 1.3e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 CCC71995.1 - 7.2e-12 45.3 0.0 9.6e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 CCC71995.1 - 0.002 17.8 0.6 0.02 14.5 0.2 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily ABC_tran PF00005.22 CCC71996.1 - 5e-59 198.4 0.3 1.9e-34 118.8 0.0 3.0 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 CCC71996.1 - 5.9e-47 160.3 44.3 6.8e-29 101.1 6.0 3.9 5 0 0 5 5 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 CCC71996.1 - 1.1e-12 48.5 3.6 5.8e-07 29.7 1.1 3.9 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 CCC71996.1 - 6.7e-11 41.8 7.5 3.6e-07 29.6 0.4 4.1 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCC71996.1 - 1e-10 42.2 5.9 2.6e-05 24.6 0.3 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 CCC71996.1 - 1.8e-07 30.5 0.7 0.003 17.0 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 CCC71996.1 - 9.4e-07 28.8 0.3 0.024 14.6 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 CCC71996.1 - 2.1e-06 28.2 0.1 0.18 12.2 0.0 3.3 3 0 0 3 3 2 2 Miro-like protein T2SE PF00437.15 CCC71996.1 - 2.7e-06 26.4 0.0 0.0018 17.2 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 CCC71996.1 - 2.8e-06 26.6 0.0 0.023 13.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 CCC71996.1 - 1e-05 26.3 0.0 0.087 13.6 0.0 3.1 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 CCC71996.1 - 4.5e-05 23.5 0.0 0.62 10.2 0.0 3.2 2 1 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CCC71996.1 - 0.0001 21.4 0.1 0.37 9.8 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin DUF87 PF01935.12 CCC71996.1 - 0.00047 20.0 1.8 0.75 9.5 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_18 PF13238.1 CCC71996.1 - 0.00073 19.8 0.1 1.5 9.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 CCC71996.1 - 0.00073 19.2 0.2 1.3 8.7 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 CCC71996.1 - 0.00083 19.3 0.2 1.1 9.1 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 CCC71996.1 - 0.0011 18.4 0.0 0.44 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 CCC71996.1 - 0.0012 18.4 0.0 5.1 6.5 0.0 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 CCC71996.1 - 0.0017 17.8 0.2 0.86 9.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA PF00004.24 CCC71996.1 - 0.0018 18.5 0.0 1.2 9.3 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Guanylate_kin PF00625.16 CCC71996.1 - 0.0024 17.3 0.2 1.2 8.5 0.0 3.3 3 0 0 3 3 3 1 Guanylate kinase Dynamin_N PF00350.18 CCC71996.1 - 0.0025 17.6 1.8 0.59 9.9 0.0 2.9 3 0 0 3 3 2 1 Dynamin family AAA_14 PF13173.1 CCC71996.1 - 0.0038 17.1 0.0 2.5 8.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 CCC71996.1 - 0.0039 16.6 0.1 0.22 10.9 0.0 2.5 2 0 0 2 2 2 1 AAA-like domain cobW PF02492.14 CCC71996.1 - 0.0067 15.8 0.2 0.6 9.5 0.0 2.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 CCC71996.1 - 0.02 14.7 0.0 3.2 7.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 CCC71996.1 - 0.02 13.4 0.1 2.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.1 CCC71996.1 - 0.036 13.6 0.7 7.2 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 CCC71996.1 - 0.044 13.3 0.0 16 5.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain RhodobacterPufX PF11511.3 CCC71996.1 - 0.12 11.8 1.1 8.7 5.8 0.0 3.5 3 0 0 3 3 2 0 Intrinsic membrane protein PufX Mg_chelatase PF01078.16 CCC71996.1 - 0.14 11.2 0.0 3.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ArgK PF03308.11 CCC71996.1 - 0.15 10.7 0.7 0.27 9.9 0.1 1.6 2 0 0 2 2 2 0 ArgK protein AAA_19 PF13245.1 CCC71996.1 - 0.33 10.7 0.5 2.8 7.7 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Sugar_tr PF00083.19 CCC71997.1 - 6.4e-161 535.9 31.3 7.4e-161 535.7 21.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 CCC71997.1 - 4.5e-32 111.1 30.4 2.3e-31 108.7 14.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 CCC71997.1 - 0.00019 19.8 2.4 0.00035 18.8 1.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3589 PF12141.3 CCC71998.1 - 1.8e-85 287.1 0.0 3.1e-85 286.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) ADH_zinc_N PF00107.21 CCC71999.1 - 1.8e-17 63.1 0.2 3.1e-17 62.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.3 CCC71999.1 - 0.03 13.4 0.1 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) LAB_N PF07578.6 CCC71999.1 - 0.061 13.2 0.3 0.16 11.8 0.2 1.7 1 0 0 1 1 1 0 Lipid A Biosynthesis N-terminal domain DUF3589 PF12141.3 CCC72000.1 - 1.7e-85 287.1 0.0 3.1e-85 286.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3589) DUF4029 PF13221.1 CCC72000.1 - 0.12 12.7 0.2 1.3 9.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4029) Lectin_leg-like PF03388.8 CCC72001.1 - 4.5e-46 156.8 0.1 6.9e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Legume-like lectin family DUF2629 PF10945.3 CCC72001.1 - 0.06 12.7 0.1 0.28 10.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2629) V-SNARE_C PF12352.3 CCC72003.1 - 7.7e-08 32.2 1.2 2.3e-07 30.7 0.8 1.9 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 CCC72003.1 - 0.0029 17.2 1.0 0.0029 17.2 0.7 2.1 2 1 0 2 2 2 1 Sec20 TPR_MLP1_2 PF07926.7 CCC72003.1 - 0.046 13.4 3.0 0.036 13.8 0.6 1.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Myosin_tail_1 PF01576.14 CCC72003.1 - 0.062 11.0 1.2 0.088 10.5 0.8 1.2 1 0 0 1 1 1 0 Myosin tail FliD_N PF02465.13 CCC72003.1 - 0.12 12.7 6.1 3.1 8.2 0.2 2.5 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Mod_r PF07200.8 CCC72003.1 - 0.12 12.2 3.5 0.32 10.8 0.3 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein RCC1 PF00415.13 CCC72004.1 - 3.9e-19 68.5 0.4 0.00021 21.4 0.1 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 CCC72004.1 - 2.1e-13 49.4 6.9 9.7e-08 31.4 0.1 3.5 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat Ribosomal_L16 PF00252.13 CCC72005.1 - 3.1e-33 114.3 0.1 3.9e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e zf-C2H2_jaz PF12171.3 CCC72006.1 - 4e-08 33.1 7.2 4e-08 33.1 5.0 2.2 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 CCC72006.1 - 0.00043 20.3 0.3 0.00086 19.3 0.2 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Microtub_bind PF13931.1 CCC72006.1 - 0.045 13.9 1.4 0.34 11.0 0.0 2.2 1 1 1 2 2 2 0 Kinesin-associated microtubule-binding DUF2743 PF10899.3 CCC72006.1 - 0.095 12.0 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2743) OTU PF02338.14 CCC72007.1 - 1.7e-11 44.7 0.0 3.2e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease zf-C2H2_2 PF12756.2 CCC72007.1 - 0.084 12.9 0.3 0.19 11.8 0.1 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) GRAM PF02893.15 CCC72008.1 - 5.9e-17 60.9 0.1 1.3e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 GRAM domain NOA36 PF06524.7 CCC72008.1 - 8 5.6 7.3 15 4.7 5.1 1.4 1 0 0 1 1 1 0 NOA36 protein Med14 PF08638.6 CCC72009.1 - 1.6e-60 203.6 4.2 1.6e-60 203.6 2.9 2.2 2 0 0 2 2 2 1 Mediator complex subunit MED14 ADH_zinc_N PF00107.21 CCC72010.1 - 1.3e-27 95.9 0.2 2.7e-27 94.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 CCC72010.1 - 4.5e-27 93.9 0.1 1e-26 92.7 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 CCC72010.1 - 8.5e-05 23.4 0.0 0.00016 22.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 CCC72010.1 - 0.14 11.5 0.2 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GTP_EFTU PF00009.22 CCC72011.1 - 1.5e-60 203.8 0.0 4.7e-60 202.2 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 CCC72011.1 - 8.4e-37 125.3 0.0 2.1e-36 124.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 CCC72011.1 - 3e-29 100.6 0.0 6.5e-29 99.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 CCC72011.1 - 3.1e-23 81.4 0.0 7.4e-23 80.2 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 CCC72011.1 - 5.4e-13 48.8 0.3 1.5e-12 47.4 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 Miro PF08477.8 CCC72011.1 - 0.043 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein DUF442 PF04273.8 CCC72011.1 - 0.051 13.4 0.0 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Putative phosphatase (DUF442) rRNA_processing PF08524.6 CCC72012.1 - 2.6e-44 150.5 36.7 3.1e-44 150.3 25.4 1.0 1 0 0 1 1 1 1 rRNA processing PV-1 PF06637.6 CCC72012.1 - 0.2 10.2 11.2 0.22 10.0 7.8 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) PPR_2 PF13041.1 CCC72013.1 - 2.3e-13 49.8 9.8 0.02 14.8 0.0 8.3 7 2 2 9 9 9 6 PPR repeat family PPR PF01535.15 CCC72013.1 - 5.5e-13 47.9 6.3 0.05 13.5 0.0 9.7 10 0 0 10 10 10 4 PPR repeat PPR_3 PF13812.1 CCC72013.1 - 3.6e-11 42.4 0.3 3 8.3 0.0 8.2 9 0 0 9 9 9 3 Pentatricopeptide repeat domain TPR_14 PF13428.1 CCC72013.1 - 0.0001 22.6 0.0 25 5.8 0.0 5.5 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_19 PF14559.1 CCC72013.1 - 0.0015 18.8 0.1 0.91 9.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat rve PF00665.21 CCC72014.1 - 7.7e-06 26.0 0.0 9.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 CCC72014.1 - 0.099 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Integrase core domain Sec34 PF04136.10 CCC72016.1 - 0.019 14.6 0.2 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Sec34-like family Tubulin PF00091.20 CCC72018.1 - 1.1e-68 231.3 0.0 2e-68 230.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 CCC72018.1 - 2.5e-47 160.0 0.3 1.2e-46 157.8 0.1 2.0 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 CCC72018.1 - 0.00091 18.7 0.0 0.002 17.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 CCC72018.1 - 0.006 16.6 0.0 0.015 15.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain DUF3115 PF11312.3 CCC72019.1 - 5.5e-99 331.0 0.1 6.3e-99 330.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) DUP PF00674.13 CCC72019.1 - 0.015 15.2 0.2 3.1 7.8 0.1 2.5 2 0 0 2 2 2 0 DUP family CheR PF01739.13 CCC72019.1 - 0.02 14.1 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Ribosomal_L22e PF01776.12 CCC72020.1 - 5.2e-43 145.5 0.7 6.8e-43 145.2 0.5 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family RNase_T PF00929.19 CCC72021.1 - 4e-32 111.7 0.4 5.9e-32 111.2 0.2 1.3 1 0 0 1 1 1 1 Exonuclease DUF2237 PF09996.4 CCC72021.1 - 0.029 13.8 0.1 0.05 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2237) Glyco_hydro_47 PF01532.15 CCC72022.1 - 5.8e-83 279.0 0.7 1.1e-82 278.0 0.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 CAMP_factor PF07373.6 CCC72023.1 - 0.021 14.3 0.0 0.023 14.2 0.0 1.0 1 0 0 1 1 1 0 CAMP factor (Cfa) WD40 PF00400.27 CCC72025.1 - 2.9e-11 42.7 3.9 0.013 15.3 0.0 6.1 6 0 0 6 6 6 3 WD domain, G-beta repeat Macoilin PF09726.4 CCC72025.1 - 1.1 7.4 7.4 1.2 7.3 5.1 1.2 1 0 0 1 1 1 0 Transmembrane protein CENP-T PF15511.1 CCC72025.1 - 2.5 7.2 36.2 0.15 11.2 18.9 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Menin PF05053.8 CCC72025.1 - 6 4.9 10.9 8.5 4.4 7.6 1.2 1 0 0 1 1 1 0 Menin ApbA_C PF08546.6 CCC72026.1 - 0.018 15.0 0.0 0.048 13.6 0.0 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Histone_HNS PF00816.16 CCC72027.1 - 0.065 13.7 1.6 0.08 13.4 0.2 1.7 1 1 1 2 2 2 0 H-NS histone family BRF1 PF07741.8 CCC72027.1 - 4.3 7.6 10.9 1.5e+02 2.6 7.5 2.3 1 1 0 1 1 1 0 Brf1-like TBP-binding domain Fcf2 PF08698.6 CCC72028.1 - 3.8e-31 107.0 0.6 3.8e-31 107.0 0.4 2.0 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing PRP1_N PF06424.7 CCC72028.1 - 0.017 15.4 3.2 0.017 15.4 2.2 1.7 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal V_ATPase_I PF01496.14 CCC72028.1 - 0.034 12.0 4.4 0.038 11.8 3.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Phosphoesterase PF04185.9 CCC72028.1 - 0.2 10.8 1.8 0.12 11.5 0.2 1.5 2 0 0 2 2 2 0 Phosphoesterase family CENP-C_mid PF15620.1 CCC72028.1 - 1.2 8.8 11.7 4.5 6.9 3.4 2.0 1 1 1 2 2 2 0 Centromere assembly component CENP-C middle DNMT3B-binding region Pyr_redox_dim PF02852.17 CCC72029.1 - 1.1e-41 141.3 0.0 3.8e-41 139.5 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 CCC72029.1 - 3.6e-37 128.1 14.1 7.1e-35 120.7 9.8 3.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 CCC72029.1 - 3.3e-21 75.4 7.8 2.5e-18 66.2 0.9 3.0 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 CCC72029.1 - 7.5e-14 51.6 0.8 2.2e-10 40.1 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 CCC72029.1 - 3.9e-10 40.1 0.6 8.7e-06 25.9 0.1 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 CCC72029.1 - 1.7e-07 30.4 2.9 1.7e-07 30.4 2.0 2.7 2 1 1 3 3 3 2 FAD binding domain GIDA PF01134.17 CCC72029.1 - 3.1e-07 29.5 10.2 9.4e-07 28.0 5.3 2.6 1 1 1 2 2 2 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 CCC72029.1 - 4.7e-07 29.7 4.7 0.00075 19.4 0.8 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 CCC72029.1 - 2.2e-05 23.7 8.8 0.012 14.7 0.6 3.4 3 0 0 3 3 3 2 FAD binding domain Thi4 PF01946.12 CCC72029.1 - 2.7e-05 23.4 3.1 0.00032 19.8 0.1 2.4 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 CCC72029.1 - 6.5e-05 21.5 14.7 0.00022 19.8 0.9 3.8 3 1 1 4 4 4 2 HI0933-like protein K_oxygenase PF13434.1 CCC72029.1 - 0.00014 20.9 1.2 0.057 12.3 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 CCC72029.1 - 0.00019 20.4 15.6 0.0036 16.2 0.1 3.6 3 1 1 4 4 4 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 CCC72029.1 - 0.029 13.9 1.8 3.6 7.1 0.0 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain PTS_IIB PF02302.12 CCC72029.1 - 0.036 14.5 1.1 8 7.0 0.1 3.0 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit 3HCDH_N PF02737.13 CCC72029.1 - 0.39 10.3 6.2 0.094 12.3 0.4 2.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 CCC72029.1 - 5.9 5.6 6.8 0.38 9.6 0.4 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein WW PF00397.21 CCC72031.1 - 4.2e-08 32.9 0.7 4.2e-08 32.9 0.5 1.8 2 0 0 2 2 2 1 WW domain DUF2076 PF09849.4 CCC72031.1 - 0.014 15.4 33.1 0.43 10.5 22.9 2.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF605 PF04652.11 CCC72031.1 - 0.027 13.8 15.4 0.027 13.8 10.7 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 CCC72031.1 - 0.028 12.7 19.8 0.028 12.6 13.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_gE PF02480.11 CCC72031.1 - 0.032 12.5 1.7 0.037 12.2 0.7 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E TFIIA PF03153.8 CCC72031.1 - 2.1 8.1 10.3 2.3 8.0 7.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DAO PF01266.19 CCC72032.1 - 2.4e-09 36.5 0.0 3.2e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 CCC72032.1 - 0.18 10.7 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Arc_PepC_II PF06847.6 CCC72034.1 - 0.14 12.6 0.7 0.7 10.3 0.0 2.2 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II DEAD PF00270.24 CCC72037.1 - 8.6e-38 129.4 0.1 1.8e-37 128.4 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC72037.1 - 1.3e-21 76.2 0.0 3.7e-21 74.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 CCC72037.1 - 6.8e-16 57.5 0.1 2.3e-15 55.8 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 CCC72037.1 - 0.00048 19.9 0.0 0.00048 19.9 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 CCC72037.1 - 0.0074 15.1 0.0 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Fibrinogen_C PF00147.13 CCC72038.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Fibrinogen beta and gamma chains, C-terminal globular domain Agglutinin PF07468.6 CCC72039.1 - 0.072 13.0 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Agglutinin SIR2 PF02146.12 CCC72040.1 - 1.6e-53 181.0 0.0 2.2e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 Sir2 family Peptidase_C48 PF02902.14 CCC72041.1 - 1.2e-40 139.4 0.5 1.2e-40 139.4 0.4 2.4 3 1 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Rabaptin PF03528.10 CCC72041.1 - 1.3 9.0 12.0 0.027 14.3 1.8 2.6 1 1 1 2 2 2 0 Rabaptin Ras PF00071.17 CCC72042.1 - 1.7e-64 216.0 0.1 2.2e-64 215.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC72042.1 - 3.2e-20 72.7 0.2 5.9e-20 71.9 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 CCC72042.1 - 1.2e-18 66.9 0.2 1.5e-18 66.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCC72042.1 - 1.2e-07 31.3 0.1 8.1e-07 28.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 CCC72042.1 - 2e-07 30.4 0.0 2.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 CCC72042.1 - 7.2e-07 28.5 0.1 9.2e-07 28.2 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 CCC72042.1 - 7.5e-06 25.8 0.1 1.3e-05 25.1 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 CCC72042.1 - 0.00075 18.8 0.1 0.01 15.1 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 CCC72042.1 - 0.0016 18.5 0.1 0.021 14.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain G-alpha PF00503.15 CCC72042.1 - 0.0024 16.6 0.4 0.31 9.6 0.0 2.5 1 1 1 2 2 2 1 G-protein alpha subunit DUF258 PF03193.11 CCC72042.1 - 0.0062 15.7 0.2 0.011 14.9 0.0 1.6 2 1 0 2 2 2 1 Protein of unknown function, DUF258 MCM PF00493.18 CCC72042.1 - 0.0087 14.8 0.0 0.016 13.9 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family AAA_16 PF13191.1 CCC72042.1 - 0.013 15.5 0.7 0.054 13.4 0.5 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 CCC72042.1 - 0.014 14.2 0.0 0.035 13.0 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 CCC72042.1 - 0.02 14.4 0.2 0.062 12.8 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_14 PF13173.1 CCC72042.1 - 0.043 13.7 0.2 0.24 11.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 CCC72042.1 - 0.072 12.5 0.0 0.42 10.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 CCC72042.1 - 0.11 12.7 0.0 0.55 10.4 0.0 2.0 1 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-C2H2 PF00096.21 CCC72043.1 - 3.6e-12 45.8 6.5 1.4e-05 25.1 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 CCC72043.1 - 4.7e-10 39.2 6.2 2.3e-07 30.7 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 CCC72043.1 - 7.7e-10 38.4 4.4 1.6e-05 24.8 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCC72043.1 - 0.0012 18.8 0.2 0.13 12.4 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 CCC72043.1 - 0.0015 18.4 0.9 1.1 9.2 0.0 2.2 2 0 0 2 2 2 2 Zinc ribbon domain zf-tcix PF14952.1 CCC72043.1 - 0.0041 16.4 2.4 0.48 9.7 0.2 2.2 2 0 0 2 2 2 2 Putative treble-clef, zinc-finger, Zn-binding zf-C2HC_2 PF13913.1 CCC72043.1 - 0.0048 16.5 0.4 1.8 8.3 0.0 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.2 CCC72043.1 - 0.01 15.9 6.5 0.047 13.9 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type Ogr_Delta PF04606.7 CCC72043.1 - 0.022 14.4 0.7 0.032 13.9 0.5 1.3 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger PRP21_like_P PF12230.3 CCC72043.1 - 0.038 13.4 0.7 0.047 13.1 0.1 1.5 1 1 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein zf-ribbon_3 PF13248.1 CCC72043.1 - 0.04 13.1 0.3 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-BED PF02892.10 CCC72043.1 - 0.051 13.3 5.6 0.55 10.0 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger zf-Di19 PF05605.7 CCC72043.1 - 0.085 12.9 0.8 0.29 11.2 0.5 1.9 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding OrfB_Zn_ribbon PF07282.6 CCC72043.1 - 0.092 12.4 0.8 0.18 11.4 0.5 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-TRAF PF02176.13 CCC72043.1 - 0.12 12.7 0.6 0.24 11.8 0.3 1.5 1 1 0 1 1 1 0 TRAF-type zinc finger FYVE PF01363.16 CCC72043.1 - 0.21 11.4 2.2 0.99 9.3 1.5 1.9 1 1 0 1 1 1 0 FYVE zinc finger UPF0547 PF10571.4 CCC72043.1 - 0.33 10.6 2.5 1.3 8.8 1.7 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-C2H2_2 PF12756.2 CCC72043.1 - 0.48 10.5 3.7 1.1 9.4 0.1 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) ADK_lid PF05191.9 CCC72043.1 - 0.81 9.4 3.9 2.4 7.9 0.2 2.5 2 0 0 2 2 2 0 Adenylate kinase, active site lid Pil1 PF13805.1 CCC72044.1 - 1.6e-149 496.4 0.8 1.9e-149 496.2 0.5 1.0 1 0 0 1 1 1 1 Eisosome component PIL1 PCP_red PF08369.5 CCC72044.1 - 0.014 15.2 3.0 0.13 12.1 0.1 3.0 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit DASH_Dad3 PF08656.5 CCC72044.1 - 0.2 11.3 1.3 7.5 6.3 0.3 2.8 2 1 0 2 2 2 0 DASH complex subunit Dad3 COPI_C PF06957.6 CCC72044.1 - 1.8 6.9 8.1 15 3.9 5.9 2.0 2 0 0 2 2 2 0 Coatomer (COPI) alpha subunit C-terminus PPR_2 PF13041.1 CCC72045.1 - 2.3e-10 40.2 9.2 0.00012 21.9 0.5 4.4 4 0 0 4 4 4 3 PPR repeat family PPR_3 PF13812.1 CCC72045.1 - 0.0002 21.4 1.5 0.33 11.3 0.0 4.4 4 0 0 4 4 4 1 Pentatricopeptide repeat domain Mpv17_PMP22 PF04117.7 CCC72046.1 - 3.8e-29 100.1 7.4 3.8e-29 100.1 5.1 1.6 2 0 0 2 2 2 1 Mpv17 / PMP22 family DUF4361 PF14274.1 CCC72046.1 - 0.12 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4361) Cucumo_coat PF00760.13 CCC72047.1 - 0.14 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Cucumovirus coat protein zf-TFIIIC PF12660.2 CCC72048.1 - 2.9e-09 36.7 0.0 6.4e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex TFIIIC_delta PF12657.2 CCC72048.1 - 0.013 15.2 0.0 0.032 13.9 0.0 1.7 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term DEAD_2 PF06733.10 CCC72049.1 - 2.4e-48 163.8 0.1 4.4e-48 162.9 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 CCC72049.1 - 2.9e-48 163.9 0.0 1e-47 162.2 0.0 1.9 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD PF00270.24 CCC72049.1 - 0.00011 21.7 0.0 0.076 12.5 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 CCC72049.1 - 0.00026 20.8 0.8 0.21 11.4 0.0 3.0 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 CCC72049.1 - 0.00028 21.0 0.3 0.073 13.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 CCC72049.1 - 0.0057 15.9 0.4 0.63 9.2 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA PF00004.24 CCC72049.1 - 0.14 12.3 0.6 2.8 8.1 0.0 2.9 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Ribosomal_S16 PF00886.14 CCC72052.1 - 8.6e-26 89.4 0.0 1.2e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 PDR_assoc PF08370.6 CCC72052.1 - 0.14 11.7 0.0 0.29 10.6 0.0 1.6 1 0 0 1 1 1 0 Plant PDR ABC transporter associated KOW PF00467.24 CCC72053.1 - 0.0011 18.6 0.5 0.0011 18.6 0.3 1.9 2 0 0 2 2 2 1 KOW motif Glyco_hydro_72 PF03198.9 CCC72054.1 - 1.4e-137 457.9 7.0 1.9e-137 457.4 4.8 1.2 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 CCC72054.1 - 5.5e-14 52.4 0.2 5.5e-14 52.4 0.1 2.0 2 0 0 2 2 2 1 X8 domain Glucan_synthase PF02364.10 CCC72055.1 - 0 1450.8 0.0 0 1450.3 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 CCC72055.1 - 1.9e-39 134.1 0.2 5.2e-39 132.7 0.1 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 Ribosomal_S25 PF03297.10 CCC72057.1 - 1.3e-42 144.1 4.7 1.4e-42 143.9 3.2 1.0 1 0 0 1 1 1 1 S25 ribosomal protein Ftsk_gamma PF09397.5 CCC72057.1 - 0.00047 19.8 0.2 0.0007 19.2 0.1 1.3 1 0 0 1 1 1 1 Ftsk gamma domain TAF4 PF05236.9 CCC72057.1 - 0.041 13.1 0.3 0.044 13.0 0.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family HTH_CodY PF08222.6 CCC72057.1 - 0.061 12.6 0.1 0.097 12.0 0.1 1.3 1 0 0 1 1 1 0 CodY helix-turn-helix domain RPA_C PF08784.6 CCC72057.1 - 0.063 13.6 0.0 0.078 13.4 0.0 1.1 1 0 0 1 1 1 0 Replication protein A C terminal HTH_DeoR PF08220.7 CCC72057.1 - 0.08 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain EAP30 PF04157.11 CCC72057.1 - 0.094 11.8 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family Ran_BP1 PF00638.13 CCC72058.1 - 1.1e-34 119.1 0.0 2e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 RanBP1 domain NUP50 PF08911.6 CCC72058.1 - 6.7e-11 42.4 2.6 6.7e-11 42.4 1.8 4.7 4 1 0 4 4 4 1 NUP50 (Nucleoporin 50 kDa) MA3 PF02847.12 CCC72059.1 - 8.9e-29 99.4 0.6 3.7e-28 97.5 0.2 2.3 2 0 0 2 2 2 1 MA3 domain MIF4G PF02854.14 CCC72059.1 - 6.2e-22 78.0 5.6 1.7e-21 76.6 3.9 1.8 1 0 0 1 1 1 1 MIF4G domain Evr1_Alr PF04777.8 CCC72060.1 - 3.1e-30 103.9 6.1 3.7e-30 103.6 3.2 1.8 2 0 0 2 2 2 1 Erv1 / Alr family WH2 PF02205.15 CCC72061.1 - 3.7e-14 51.7 0.4 3.8e-10 39.0 0.1 3.2 3 0 0 3 3 3 2 WH2 motif PWI PF01480.12 CCC72062.1 - 0.0012 18.8 0.8 0.0068 16.4 0.4 2.5 2 0 0 2 2 2 1 PWI domain DUF1554 PF07588.6 CCC72063.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1554) DUF4116 PF13475.1 CCC72064.1 - 0.45 10.0 4.9 15 5.1 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4116) Reo_sigmaC PF04582.7 CCC72064.1 - 1.8 7.6 5.7 1.6 7.8 2.4 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein UPF0228 PF05727.6 CCC72064.1 - 5.6 6.7 12.6 0.06 13.1 1.5 2.6 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0228) MF_alpha_N PF05436.6 CCC72065.1 - 1.3e-31 108.0 0.9 1.8e-31 107.6 0.6 1.2 1 0 0 1 1 1 1 Mating factor alpha precursor N-terminus MF_alpha PF04648.7 CCC72065.1 - 1.2e-15 56.6 24.2 6.2e-05 22.9 2.0 3.2 3 0 0 3 3 3 3 Yeast mating factor alpha hormone Mid2 PF04478.7 CCC72066.1 - 3.5e-62 208.3 0.3 3.5e-62 208.3 0.2 2.6 3 1 0 3 3 3 1 Mid2 like cell wall stress sensor TFIIA PF03153.8 CCC72066.1 - 0.026 14.4 1.6 0.031 14.1 1.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF912 PF06024.7 CCC72066.1 - 0.78 9.8 0.1 0.78 9.8 0.0 2.5 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rax2 PF12768.2 CCC72066.1 - 1.7 7.8 16.5 11 5.0 11.4 2.2 1 1 0 1 1 1 0 Cortical protein marker for cell polarity SKG6 PF08693.5 CCC72066.1 - 1.9 7.8 9.3 0.088 12.1 1.6 2.6 2 0 0 2 2 2 0 Transmembrane alpha-helix domain BRCT PF00533.21 CCC72067.1 - 3.8e-11 42.9 0.1 1.2e-10 41.3 0.1 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 CCC72067.1 - 0.00014 21.5 0.0 0.0003 20.6 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain DUF3006 PF11213.3 CCC72067.1 - 0.00076 19.1 0.0 0.0028 17.3 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3006) fn3 PF00041.16 CCC72067.1 - 0.0046 17.0 0.0 0.014 15.5 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III domain CTP_transf_2 PF01467.21 CCC72068.1 - 2.9e-36 124.8 0.0 4.2e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase HABP4_PAI-RBP1 PF04774.10 CCC72070.1 - 1.7e-05 25.2 3.6 2.2e-05 24.9 2.5 1.3 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family RE_LlaJI PF09563.5 CCC72070.1 - 0.0033 16.1 0.5 0.0033 16.1 0.3 1.1 1 0 0 1 1 1 1 LlaJI restriction endonuclease DUF4112 PF13430.1 CCC72071.1 - 5.2e-33 113.1 0.3 6.8e-33 112.7 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) NB PF04159.8 CCC72071.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 NB glycoprotein POP1 PF06978.6 CCC72071.1 - 0.32 10.6 5.3 0.67 9.5 0.1 2.1 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 Pmp3 PF01679.12 CCC72073.1 - 8e-17 60.6 5.5 1e-16 60.3 3.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF843 PF05814.6 CCC72073.1 - 0.14 12.0 3.0 0.14 11.9 0.2 2.0 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF843) Pkinase PF00069.20 CCC72075.1 - 2.5e-68 230.0 0.2 8.9e-67 224.9 0.2 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 CCC72075.1 - 2.5e-48 164.4 0.1 2.9e-46 157.6 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 CCC72075.1 - 3.4e-32 110.5 0.2 7.8e-32 109.3 0.2 1.7 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 CCC72075.1 - 4.9e-10 39.1 0.1 1.9e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 CCC72075.1 - 4.3e-08 32.4 0.0 5.6e-07 28.7 0.0 2.2 2 0 0 2 2 2 1 Kinase-like SAM_1 PF00536.25 CCC72075.1 - 7.4e-07 29.2 0.1 2.3e-06 27.6 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pex24p PF06398.6 CCC72076.1 - 1.7e-85 286.9 7.7 1.7e-85 286.9 5.3 1.4 2 0 0 2 2 2 1 Integral peroxisomal membrane peroxin zf-C3HC4_2 PF13923.1 CCC72077.1 - 5.7e-10 39.0 9.3 1.1e-09 38.1 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 CCC72077.1 - 7.6e-10 38.2 3.0 1.6e-09 37.2 2.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 CCC72077.1 - 2.6e-09 36.6 4.9 4.4e-09 35.8 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC72077.1 - 2.1e-07 30.5 8.7 4e-07 29.6 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 CCC72077.1 - 3.8e-07 29.8 6.3 7.3e-07 28.9 4.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 CCC72077.1 - 1.1e-05 24.9 8.2 2.4e-05 23.9 5.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 CCC72077.1 - 0.00014 21.6 7.9 0.00034 20.4 5.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 CCC72077.1 - 0.0011 18.6 2.7 0.0035 17.0 1.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 CCC72077.1 - 0.043 13.9 4.2 0.09 12.8 2.9 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 CCC72077.1 - 0.046 13.2 4.0 0.1 12.1 2.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 CCC72077.1 - 0.062 13.0 3.1 0.12 12.1 2.2 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.9 CCC72077.1 - 0.54 9.7 4.3 1.2 8.7 3.0 1.5 1 0 0 1 1 1 0 P-11 zinc finger Mus7 PF09462.5 CCC72078.1 - 1.3e-30 106.8 12.3 5.8e-20 71.6 3.0 2.3 1 1 0 2 2 2 2 Mus7/MMS22 family AIP3 PF03915.8 CCC72079.1 - 2.3e-147 491.3 17.1 2.3e-147 491.3 11.8 1.7 2 0 0 2 2 2 1 Actin interacting protein 3 SpoIISA_toxin PF14171.1 CCC72079.1 - 0.032 13.5 2.1 0.46 9.6 0.0 2.5 2 0 0 2 2 2 0 Toxin SpoIISA, type II toxin-antitoxin system HSBP1 PF06825.7 CCC72079.1 - 1.1 8.9 5.0 1.7 8.2 0.5 2.9 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Telomerase_RBD PF12009.3 CCC72080.1 - 3.9e-33 114.2 4.9 3.9e-33 114.2 3.4 2.9 3 0 0 3 3 3 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 CCC72080.1 - 7e-10 38.6 1.4 4.1e-09 36.1 0.9 2.3 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) dCMP_cyt_deam_1 PF00383.17 CCC72081.1 - 5.7e-10 38.7 0.0 1.1e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SNF5 PF04855.7 CCC72082.1 - 5.6e-63 212.6 0.9 3.9e-60 203.3 0.6 2.2 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Ig_2 PF13895.1 CCC72082.1 - 0.1 12.7 0.0 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 Immunoglobulin domain EF1_GNE PF00736.14 CCC72083.1 - 2.5e-32 110.4 1.4 4.5e-32 109.5 1.0 1.4 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 CCC72083.1 - 3.1e-13 49.6 6.1 3.1e-13 49.6 4.2 3.1 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 CCC72083.1 - 0.0041 17.5 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Cwf_Cwc_15 PF04889.7 CCC72083.1 - 0.022 14.5 2.1 0.033 13.8 1.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein GST_C_2 PF13410.1 CCC72083.1 - 0.055 13.3 0.1 0.77 9.6 0.0 2.2 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 CCC72083.1 - 0.16 11.9 2.3 0.74 9.8 0.2 2.5 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DNA_pol3_a_NII PF11490.3 CCC72083.1 - 3.2 7.3 5.8 4.1 7.0 0.0 2.3 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II MRC1 PF09444.5 CCC72083.1 - 4.9 7.4 11.2 0.71 10.1 4.4 1.9 2 0 0 2 2 2 0 MRC1-like domain Vps8 PF12816.2 CCC72084.1 - 8.6e-54 181.7 12.2 1.3e-53 181.2 2.9 3.2 3 0 0 3 3 3 1 Golgi CORVET complex core vacuolar protein 8 zf-rbx1 PF12678.2 CCC72084.1 - 0.00013 21.9 1.6 0.00031 20.7 1.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 CCC72084.1 - 0.001 18.7 1.7 0.0024 17.4 1.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 CCC72084.1 - 0.17 11.9 2.0 0.43 10.6 1.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 CCC72084.1 - 0.35 10.6 5.1 0.78 9.5 3.5 1.6 1 1 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 CCC72084.1 - 0.36 10.5 2.2 0.92 9.2 1.5 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_2 PF13639.1 CCC72084.1 - 0.41 10.5 4.9 0.068 13.0 0.6 1.8 2 0 0 2 2 2 0 Ring finger domain B-block_TFIIIC PF04182.7 CCC72085.1 - 2.8e-18 65.5 0.9 1.1e-17 63.6 0.2 2.4 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC AcetDehyd-dimer PF09290.6 CCC72085.1 - 0.005 16.7 0.1 1.7 8.5 0.1 3.2 3 0 0 3 3 3 2 Prokaryotic acetaldehyde dehydrogenase, dimerisation eIF3g PF12353.3 CCC72086.1 - 0.033 14.1 2.7 0.057 13.3 1.0 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 3 subunit G eIF3_p135 PF12807.2 CCC72086.1 - 0.086 12.7 0.0 0.14 12.0 0.0 1.4 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 EMP24_GP25L PF01105.19 CCC72088.1 - 7e-55 185.5 1.0 8.5e-55 185.3 0.7 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ATP-synt_8 PF00895.15 CCC72088.1 - 3.5 7.9 5.8 30 4.9 1.4 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 WD40 PF00400.27 CCC72089.1 - 1.9e-18 65.5 2.5 2.7e-10 39.7 0.5 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 CCC72089.1 - 0.00014 21.6 0.7 0.042 13.5 0.0 3.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CCC72090.1 - 4.6e-28 96.0 1.6 1.5e-05 24.6 0.3 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 CCC72090.1 - 2.5e-06 27.3 0.2 0.046 13.4 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Receptor_2B4 PF11465.3 CCC72090.1 - 0.028 14.3 0.0 0.077 12.9 0.0 1.7 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Rep_fac-A_C PF08646.5 CCC72091.1 - 4.9e-58 194.9 5.2 4.3e-54 182.1 1.8 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain tRNA_anti-codon PF01336.20 CCC72091.1 - 2.2e-16 59.4 0.2 2.2e-08 33.8 0.0 4.5 4 0 0 4 4 4 3 OB-fold nucleic acid binding domain Rep-A_N PF04057.7 CCC72091.1 - 1.1e-06 28.3 0.1 3.1e-06 26.9 0.1 1.8 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain DUF223 PF02721.9 CCC72091.1 - 0.023 14.7 0.7 0.09 12.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF223 BRCA-2_OB1 PF09103.5 CCC72091.1 - 0.076 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 tRNA_int_endo PF01974.12 CCC72092.1 - 5.1e-14 51.8 0.0 1.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Transaldolase PF00923.14 CCC72093.1 - 2.9e-99 331.8 0.4 3.4e-99 331.6 0.3 1.0 1 0 0 1 1 1 1 Transaldolase IlvC PF01450.14 CCC72094.1 - 1.8e-46 157.6 0.0 3.1e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.7 CCC72094.1 - 5.9e-46 155.8 0.0 8.3e-46 155.3 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 CCC72094.1 - 0.085 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF417 PF04224.7 CCC72095.1 - 0.13 11.5 1.6 10 5.4 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF417 eIF2A PF08662.6 CCC72096.1 - 1.6e-75 253.1 0.2 1.3e-74 250.1 0.1 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 CCC72096.1 - 0.001 18.8 0.2 6.1 6.8 0.1 4.6 4 0 0 4 4 4 1 WD domain, G-beta repeat AA_permease_2 PF13520.1 CCC72097.1 - 1.1e-84 284.4 50.1 1.4e-84 284.1 34.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 CCC72097.1 - 4.1e-20 71.5 46.3 5.5e-20 71.1 32.1 1.0 1 0 0 1 1 1 1 Amino acid permease MotA_ExbB PF01618.11 CCC72097.1 - 0.25 10.9 2.0 0.94 9.1 0.3 2.7 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family BAH PF01426.13 CCC72098.1 - 2.3e-23 82.2 0.1 4.2e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 BAH domain Bromodomain PF00439.20 CCC72098.1 - 1.6e-21 76.0 6.5 1.4e-14 53.7 0.2 2.6 2 0 0 2 2 2 2 Bromodomain Lyase_1 PF00206.15 CCC72099.1 - 1.9e-23 83.1 0.0 3.4e-23 82.3 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 CCC72099.1 - 1.1e-15 57.3 0.0 4.8e-15 55.3 0.0 2.2 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus AsiA PF09010.5 CCC72099.1 - 0.025 14.4 0.0 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Anti-Sigma Factor A DUF1331 PF07048.6 CCC72099.1 - 0.11 11.9 0.1 0.11 11.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1331) Metallophos PF00149.23 CCC72101.1 - 8.6e-11 41.6 1.5 2e-10 40.3 1.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 CCC72101.1 - 0.0017 18.2 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Methyltrn_RNA_4 PF09936.4 CCC72102.1 - 0.41 10.1 3.2 0.46 9.9 1.3 1.8 1 1 1 2 2 2 0 SAM-dependent RNA methyltransferase CENP-F_leu_zip PF10473.4 CCC72102.1 - 1.9 8.3 56.3 0.098 12.5 9.5 4.2 1 1 3 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 CCC72102.1 - 3.3 7.6 18.6 0.96 9.3 1.2 4.2 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) PIN_4 PF13638.1 CCC72103.1 - 4e-05 23.7 0.0 8.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 PIN domain Thioredoxin_9 PF14595.1 CCC72104.1 - 1.1e-05 24.9 0.0 1.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 CCC72104.1 - 0.00011 22.1 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin CaATP_NAI PF12515.3 CCC72104.1 - 0.035 13.6 0.0 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain DUF953 PF06110.6 CCC72104.1 - 0.13 11.6 0.9 0.21 11.0 0.6 1.5 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) HSP70 PF00012.15 CCC72105.1 - 2.3e-214 712.7 13.2 2.7e-214 712.5 9.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 CCC72105.1 - 2.7e-19 68.9 2.8 1.1e-16 60.3 0.9 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 CCC72105.1 - 0.0012 18.5 0.0 0.0023 17.5 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Macoilin PF09726.4 CCC72105.1 - 0.011 14.0 11.9 0.12 10.6 3.5 2.4 1 1 1 2 2 2 0 Transmembrane protein Terminase_2 PF03592.11 CCC72105.1 - 0.076 13.3 11.6 0.7 10.1 4.6 2.5 2 0 0 2 2 2 0 Terminase small subunit FtsA PF14450.1 CCC72105.1 - 0.12 12.1 6.9 3.7 7.4 0.9 4.3 3 1 0 3 3 3 0 Cell division protein FtsA tRNA-synt_His PF13393.1 CCC72105.1 - 0.18 10.7 1.6 0.39 9.7 0.1 2.0 2 0 0 2 2 2 0 Histidyl-tRNA synthetase GlutR_dimer PF00745.15 CCC72105.1 - 3.1 7.7 10.4 0.18 11.7 1.2 3.2 2 2 1 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain P21-Arc PF04062.9 CCC72106.1 - 3.8e-82 274.2 0.1 4.3e-82 274.1 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit ELO PF01151.13 CCC72107.1 - 1.7e-57 194.5 31.6 2.2e-57 194.2 21.9 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family zf-BED PF02892.10 CCC72108.1 - 8.6e-07 28.6 1.0 1.7e-06 27.7 0.7 1.5 1 0 0 1 1 1 1 BED zinc finger Nop14 PF04147.7 CCC72108.1 - 0.46 8.3 19.0 1.5 6.6 13.2 1.8 1 0 0 1 1 1 0 Nop14-like family FYDLN_acid PF09538.5 CCC72108.1 - 5.4 7.6 21.7 17 6.0 10.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C2H2 PF00096.21 CCC72109.1 - 0.00027 21.0 1.3 0.00027 21.0 0.9 5.4 5 1 0 5 5 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC72109.1 - 0.00035 20.7 1.1 0.00035 20.7 0.8 5.0 5 0 0 5 5 4 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 CCC72109.1 - 0.00044 20.0 9.0 0.0058 16.5 0.2 3.7 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 CCC72109.1 - 0.00083 19.4 8.0 0.34 11.1 0.0 3.8 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CCC72109.1 - 0.0021 18.2 1.1 0.0021 18.2 0.8 5.0 4 1 1 5 5 5 1 Zinc-finger double domain Rad50_zn_hook PF04423.9 CCC72109.1 - 0.021 14.3 1.0 0.16 11.4 0.0 2.5 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-Di19 PF05605.7 CCC72109.1 - 0.024 14.7 8.5 0.094 12.8 1.3 3.7 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF1644 PF07800.7 CCC72109.1 - 0.028 14.2 0.5 0.064 13.1 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) zf-SNAP50_C PF12251.3 CCC72109.1 - 0.17 11.2 3.8 0.25 10.6 0.2 2.3 2 1 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal zf-RING_2 PF13639.1 CCC72109.1 - 0.27 11.1 4.3 9.2 6.1 0.0 3.3 3 0 0 3 3 3 0 Ring finger domain zf-C2HC_2 PF13913.1 CCC72109.1 - 0.99 9.1 12.7 5.8 6.6 0.0 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf-RING_3 PF14369.1 CCC72109.1 - 1.2 9.1 5.4 2.8 8.0 0.1 3.3 3 0 0 3 3 3 0 zinc-finger zf-met PF12874.2 CCC72109.1 - 7.2 6.9 7.8 2.8 8.2 0.1 3.5 4 0 0 4 4 4 0 Zinc-finger of C2H2 type KRE9 PF05390.6 CCC72110.1 - 1.4e-21 76.8 3.1 2.4e-21 76.0 2.2 1.4 1 0 0 1 1 1 1 Yeast cell wall synthesis protein KRE9/KNH1 GPI-anchored PF10342.4 CCC72110.1 - 8.7e-07 29.3 0.0 1.5e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FBPase PF00316.15 CCC72112.1 - 1.4e-127 425.0 0.0 1.6e-127 424.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 CCC72112.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family SecY PF00344.15 CCC72113.1 - 9.4e-89 297.7 16.5 1.2e-88 297.3 11.5 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 CCC72113.1 - 5.3e-18 64.2 2.7 6.7e-18 63.8 0.1 2.7 2 0 0 2 2 2 1 Plug domain of Sec61p Claudin_3 PF06653.6 CCC72113.1 - 0.27 10.9 0.1 0.27 10.9 0.0 3.0 3 1 0 3 3 3 0 Tight junction protein, Claudin-like Cation_ATPase_C PF00689.16 CCC72113.1 - 0.38 10.2 12.9 1.2 8.6 2.1 3.2 2 1 1 3 3 3 0 Cation transporting ATPase, C-terminus NTP_transferase PF00483.18 CCC72114.1 - 4.6e-48 163.6 0.0 6.5e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 CCC72114.1 - 2.2e-11 42.6 2.9 8.1e-07 28.2 0.4 3.8 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 CCC72114.1 - 6.1e-11 42.6 0.0 7.6e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 CCC72114.1 - 0.00071 19.0 5.7 0.003 17.0 0.8 3.1 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 CCC72114.1 - 0.036 13.6 0.0 0.088 12.4 0.0 1.5 1 1 0 1 1 1 0 Cytidylyltransferase IspD PF01128.14 CCC72114.1 - 0.041 13.3 0.0 0.08 12.4 0.0 1.5 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CRAL_TRIO PF00650.15 CCC72115.1 - 1.2e-33 115.8 0.2 2.6e-33 114.7 0.1 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 CCC72115.1 - 2.8e-13 49.7 0.0 8.2e-13 48.2 0.0 1.9 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 CCC72115.1 - 3.3e-06 27.0 1.3 4.8e-06 26.5 0.1 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain DUF1726 PF08351.6 CCC72116.1 - 0.046 13.3 0.1 0.2 11.3 0.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1726) tRNA-synt_1 PF00133.17 CCC72117.1 - 1e-50 172.4 0.1 5.3e-18 64.3 0.2 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 CCC72117.1 - 9.1e-37 126.1 0.0 1.8e-36 125.1 0.0 1.5 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 CCC72117.1 - 6.4e-31 107.3 0.2 2e-23 82.7 0.1 4.6 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1d PF00750.14 CCC72117.1 - 2.7e-07 29.7 0.1 0.00011 21.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (R) Anticodon_1 PF08264.8 CCC72117.1 - 3.9e-05 23.4 0.5 9.2e-05 22.2 0.3 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 CCC72117.1 - 0.0011 18.1 0.0 0.017 14.2 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain SMC_N PF02463.14 CCC72118.1 - 7e-19 67.9 29.5 1.2e-13 50.8 0.3 3.4 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 CCC72118.1 - 2.4e-16 60.6 24.4 2.4e-16 60.6 16.9 5.2 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 CCC72118.1 - 0.00016 21.1 0.0 0.00042 19.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 CCC72118.1 - 0.00062 18.9 32.0 0.00062 18.9 22.2 3.5 2 2 1 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 CCC72118.1 - 0.0007 19.6 0.3 0.0007 19.6 0.2 4.4 3 2 0 3 3 3 2 AAA domain Spc7 PF08317.6 CCC72118.1 - 0.0037 15.9 9.6 0.0037 15.9 6.7 6.3 3 2 4 7 7 7 2 Spc7 kinetochore protein ABC_tran PF00005.22 CCC72118.1 - 0.025 14.8 0.1 0.025 14.8 0.1 5.8 3 2 0 3 3 3 0 ABC transporter IKI3 PF04762.7 CCC72119.1 - 0 1135.7 6.3 0 1135.7 4.3 1.5 2 0 0 2 2 2 1 IKI3 family Apc4_WD40 PF12894.2 CCC72119.1 - 0.12 11.8 0.1 0.72 9.4 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain FliL PF03748.9 CCC72120.1 - 0.11 12.4 1.0 0.26 11.3 0.1 1.8 1 1 1 2 2 2 0 Flagellar basal body-associated protein FliL Desmo_N PF06771.6 CCC72120.1 - 0.19 11.7 1.9 0.39 10.6 0.3 2.1 1 1 1 2 2 2 0 Viral Desmoplakin N-terminus DUF4549 PF15082.1 CCC72120.1 - 0.33 10.5 4.4 1.6 8.3 0.4 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4549) Vac14_Fig4_bd PF11916.3 CCC72121.1 - 7.3e-71 237.0 10.0 1.3e-70 236.2 6.3 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 CCC72121.1 - 1.8e-47 159.6 0.5 7.7e-39 132.0 0.0 4.4 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 CCC72121.1 - 2e-10 39.8 4.2 0.00022 21.0 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 CCC72121.1 - 1.6e-09 37.8 0.1 0.035 14.3 0.0 5.1 4 0 0 4 4 4 3 HEAT repeats HEAT_EZ PF13513.1 CCC72121.1 - 6.5e-08 32.8 1.3 0.35 11.4 0.0 7.2 7 1 1 8 8 8 1 HEAT-like repeat CLASP_N PF12348.3 CCC72121.1 - 5.8e-07 29.1 1.2 0.028 13.7 0.3 4.4 4 0 0 4 4 4 1 CLASP N terminal Arm PF00514.18 CCC72121.1 - 3.2e-05 23.5 2.5 4.3 7.3 0.0 4.9 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat ParcG PF10274.4 CCC72121.1 - 0.0028 17.5 8.7 0.01 15.7 0.2 3.7 2 1 0 4 4 4 1 Parkin co-regulated protein zf-C2H2_2 PF12756.2 CCC72122.1 - 1.2e-32 112.0 4.5 6.7e-30 103.1 2.0 2.7 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) DUF2856 PF11043.3 CCC72122.1 - 0.13 12.4 1.8 0.24 11.5 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2856) zf-C2H2_jaz PF12171.3 CCC72122.1 - 0.18 11.9 11.4 0.29 11.3 0.6 3.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 CCC72122.1 - 1.1 9.7 10.9 0.89 10.0 0.7 3.2 2 1 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC72122.1 - 4.6 7.8 7.2 21 5.7 0.6 3.3 2 1 1 3 3 3 0 C2H2-type zinc finger AKAP95 PF04988.7 CCC72122.1 - 7.4 6.3 15.1 0.66 9.7 1.0 3.8 4 1 0 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) DUF663 PF04950.7 CCC72124.1 - 2.5e-103 345.1 0.0 5.4e-103 344.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 CCC72124.1 - 1.6e-24 85.1 0.0 3.6e-24 84.0 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Ribosomal_S14 PF00253.16 CCC72125.1 - 6.4e-18 63.8 4.4 7e-18 63.7 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Prim_Zn_Ribbon PF08273.7 CCC72125.1 - 0.044 13.8 2.0 0.95 9.5 0.2 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF4428 PF14471.1 CCC72125.1 - 0.045 13.4 0.5 0.053 13.2 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) DUF2296 PF10058.4 CCC72125.1 - 0.16 11.7 1.8 2.1 8.1 0.0 2.1 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) RNA_POL_M_15KD PF02150.11 CCC72125.1 - 0.41 10.3 2.6 6.2 6.6 0.2 2.1 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Peptidase_M16 PF00675.15 CCC72126.1 - 1.6e-37 128.5 0.0 1.2e-36 125.7 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 CCC72126.1 - 7.7e-28 97.4 1.7 2e-17 63.4 0.0 2.8 3 0 0 3 3 3 2 Peptidase M16 inactive domain DUF575 PF04746.7 CCC72127.1 - 0.044 13.8 0.0 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF575) Activator_LAG-3 PF11498.3 CCC72127.1 - 0.83 8.3 10.9 0.86 8.2 7.5 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CFEM PF05730.6 CCC72128.1 - 1.5e-08 34.3 12.4 4.5e-08 32.8 8.6 1.9 1 0 0 1 1 1 1 CFEM domain Rrn6 PF10214.4 CCC72128.1 - 1.1 7.3 21.7 1.3 7.0 15.0 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Arrestin_N PF00339.24 CCC72129.1 - 0.00031 20.5 0.0 0.001 18.8 0.0 1.9 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain ATP-synt_10 PF05176.9 CCC72130.1 - 1.1e-67 228.0 0.1 1.3e-67 227.7 0.1 1.0 1 0 0 1 1 1 1 ATP10 protein zf-RING_5 PF14634.1 CCC72131.1 - 1.2e-07 31.3 6.1 2.7e-07 30.1 4.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-MIZ PF02891.15 CCC72131.1 - 0.0025 17.2 7.1 0.0064 15.9 4.9 1.7 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_2 PF13923.1 CCC72131.1 - 0.035 14.1 4.2 0.14 12.2 2.9 2.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCC72131.1 - 0.041 13.5 4.7 0.095 12.3 3.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 CCC72131.1 - 0.055 13.2 3.4 0.14 11.9 2.3 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Guanylin PF02058.10 CCC72131.1 - 0.079 13.0 0.2 0.079 13.0 0.2 2.3 3 0 0 3 3 3 0 Guanylin precursor SSFA2_C PF14723.1 CCC72131.1 - 4.2 7.0 8.7 1.1 9.0 3.2 2.2 2 1 0 2 2 2 0 Sperm-specific antigen 2 C-terminus COX7C PF02935.11 CCC72132.1 - 2.3e-19 68.9 1.5 2.5e-19 68.8 1.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Sec1 PF00995.18 CCC72133.1 - 1e-70 238.9 8.1 1.5e-70 238.4 5.6 1.2 1 0 0 1 1 1 1 Sec1 family UNC45-central PF11701.3 CCC72133.1 - 0.024 14.3 1.4 0.92 9.1 0.1 2.6 2 0 0 2 2 2 0 Myosin-binding striated muscle assembly central DUF1128 PF06569.6 CCC72133.1 - 0.053 13.2 0.0 0.19 11.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) AAA PF00004.24 CCC72134.1 - 1.2e-91 303.8 0.0 3.1e-44 150.3 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 CCC72134.1 - 1.8e-12 46.8 0.0 4.7e-05 22.5 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 CCC72134.1 - 2.4e-12 47.2 0.1 2.7e-06 27.5 0.0 3.4 2 2 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 CCC72134.1 - 1e-11 44.7 0.0 8.7e-05 22.2 0.0 3.9 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 CCC72134.1 - 2.9e-11 43.6 0.6 5e-05 23.4 0.1 4.5 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.9 CCC72134.1 - 1.2e-09 38.3 0.0 0.00014 21.7 0.0 3.1 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_14 PF13173.1 CCC72134.1 - 2.9e-09 36.8 0.0 0.00014 21.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 CCC72134.1 - 2.9e-07 30.4 0.0 0.00019 21.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 CCC72134.1 - 1.2e-06 27.5 0.0 0.0038 15.9 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 CCC72134.1 - 2.2e-06 28.4 0.0 0.019 15.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 CCC72134.1 - 2.5e-06 27.1 1.1 0.0013 18.4 0.1 3.4 3 0 0 3 3 2 1 Part of AAA domain RNA_helicase PF00910.17 CCC72134.1 - 1.2e-05 25.4 0.0 0.16 12.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase Arch_ATPase PF01637.13 CCC72134.1 - 1.8e-05 24.5 0.0 1.5 8.4 0.0 3.4 2 1 1 3 3 3 1 Archaeal ATPase Mg_chelatase PF01078.16 CCC72134.1 - 2.6e-05 23.5 0.2 0.08 12.0 0.0 2.7 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_N PF02359.13 CCC72134.1 - 3.5e-05 23.6 1.0 6.7e-05 22.7 0.1 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_25 PF13481.1 CCC72134.1 - 3.7e-05 23.2 6.6 0.42 9.9 0.0 4.2 2 2 2 4 4 4 2 AAA domain Sigma54_activ_2 PF14532.1 CCC72134.1 - 5.5e-05 23.2 0.0 0.046 13.7 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Bac_DnaA PF00308.13 CCC72134.1 - 5.6e-05 22.8 0.0 0.0053 16.4 0.0 2.7 2 2 0 2 2 2 1 Bacterial dnaA protein AAA_28 PF13521.1 CCC72134.1 - 8e-05 22.6 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 CCC72134.1 - 0.00014 21.0 0.0 0.12 11.4 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 CCC72134.1 - 0.00019 21.1 0.1 0.025 14.2 0.0 3.5 4 0 0 4 4 4 1 NACHT domain IstB_IS21 PF01695.12 CCC72134.1 - 0.00049 19.5 0.0 0.83 9.0 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Rad17 PF03215.10 CCC72134.1 - 0.00093 17.9 0.0 0.048 12.3 0.0 2.4 2 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 CCC72134.1 - 0.0011 18.5 0.0 1.2 8.7 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 CCC72134.1 - 0.007 15.9 0.0 0.062 12.8 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 CCC72134.1 - 0.011 15.3 0.0 1.2 8.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 CCC72134.1 - 0.012 15.8 0.0 0.29 11.4 0.0 2.7 2 1 0 2 2 2 0 ABC transporter Sigma54_activat PF00158.21 CCC72134.1 - 0.016 14.6 0.0 13 5.1 0.0 3.7 2 2 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 CCC72134.1 - 0.019 14.5 0.1 0.095 12.2 0.0 2.3 3 1 0 3 3 2 0 AAA domain DUF815 PF05673.8 CCC72134.1 - 0.019 13.9 0.0 0.91 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 CCC72134.1 - 0.027 14.0 0.2 5.2 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 CCC72134.1 - 0.038 13.6 0.1 2.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 CCC72134.1 - 0.044 14.0 0.0 1.6 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 CCC72134.1 - 0.076 11.8 0.1 0.27 9.9 0.0 1.9 3 0 0 3 3 2 0 AFG1-like ATPase NTPase_1 PF03266.10 CCC72134.1 - 0.077 12.7 0.7 2.2 7.9 0.0 3.2 2 2 2 4 4 4 0 NTPase KaiC PF06745.8 CCC72134.1 - 0.11 11.5 2.7 16 4.4 0.0 3.5 3 1 0 4 4 4 0 KaiC DSHCT PF08148.7 CCC72135.1 - 2.1e-59 199.7 0.2 5.4e-59 198.4 0.1 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 CCC72135.1 - 1.6e-22 79.8 0.1 4.2e-22 78.4 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC72135.1 - 1.4e-06 28.0 0.0 5.7e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 CCC72135.1 - 1.6e-06 27.5 0.1 1.6e-06 27.5 0.1 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain Bromodomain PF00439.20 CCC72136.1 - 5.7e-39 131.9 1.7 3.7e-19 68.4 0.1 2.6 2 0 0 2 2 2 2 Bromodomain MRC1 PF09444.5 CCC72136.1 - 0.02 15.2 10.7 0.055 13.8 7.4 1.7 1 0 0 1 1 1 0 MRC1-like domain Dus PF01207.12 CCC72137.1 - 1.2e-42 145.7 0.0 1.2e-31 109.7 0.0 2.3 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 CCC72137.1 - 0.048 13.3 7.0 0.076 12.7 0.4 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_4 PF13894.1 CCC72138.1 - 1.3e-05 25.1 15.3 0.027 14.7 0.2 3.8 3 1 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 CCC72138.1 - 3.1e-05 24.0 18.2 0.032 14.5 0.5 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 CCC72138.1 - 0.00012 22.0 1.2 0.056 13.6 0.1 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 CCC72138.1 - 0.00016 21.7 11.9 0.019 15.2 0.2 3.8 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 CCC72138.1 - 4 7.4 6.2 0.86 9.5 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2910 PF11139.3 CCC72139.1 - 0.015 14.4 1.4 0.026 13.6 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Dus PF01207.12 CCC72140.1 - 2.7e-72 243.2 0.0 3.3e-72 242.9 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Flavodoxin_2 PF02525.12 CCC72141.1 - 1.3e-54 184.7 0.0 1.5e-54 184.5 0.0 1.0 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 CCC72141.1 - 1e-12 47.8 0.0 2.1e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_4 PF12682.2 CCC72141.1 - 3.5e-05 23.2 0.3 6e-05 22.4 0.2 1.4 1 0 0 1 1 1 1 Flavodoxin DUF4050 PF13259.1 CCC72142.1 - 5.9e-22 77.8 0.5 9.2e-22 77.2 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) Utp21 PF04192.7 CCC72144.1 - 1.2e-82 276.6 1.4 1.6e-82 276.1 1.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 CCC72144.1 - 3.9e-25 86.7 7.6 9.6e-10 37.9 0.4 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 CCC72144.1 - 2.6e-05 24.0 0.5 0.031 13.9 0.0 3.6 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.10 CCC72144.1 - 0.00013 21.1 0.4 0.0043 16.1 0.1 3.2 3 1 0 3 3 3 1 CPSF A subunit region PQQ_2 PF13360.1 CCC72144.1 - 0.00028 20.4 0.0 0.025 14.0 0.0 3.0 3 1 0 3 3 3 1 PQQ-like domain Cytochrom_D1 PF02239.11 CCC72144.1 - 0.0015 16.9 0.0 0.0064 14.8 0.0 1.9 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 CCC72144.1 - 0.002 16.9 0.7 0.092 11.4 0.0 3.2 3 1 0 3 3 3 1 Nup133 N terminal like Apc4_WD40 PF12894.2 CCC72144.1 - 0.2 11.1 0.7 5.7 6.5 0.0 3.3 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain His_Phos_2 PF00328.17 CCC72145.1 - 2.6e-132 441.3 0.3 3.6e-132 440.9 0.2 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 CCC72145.1 - 8.3e-08 31.9 0.0 2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 RimK-like ATP-grasp domain PyocinActivator PF11112.3 CCC72145.1 - 0.2 11.5 2.4 0.73 9.7 0.2 2.5 2 0 0 2 2 2 0 Pyocin activator protein PrtN Ctr PF04145.10 CCC72146.1 - 1.9e-40 138.2 1.0 2.9e-40 137.6 0.7 1.3 1 0 0 1 1 1 1 Ctr copper transporter family Acyl_transf_1 PF00698.16 CCC72147.1 - 2.9e-95 319.2 0.0 6.7e-94 314.7 0.0 2.8 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 CCC72147.1 - 3.9e-36 123.1 0.0 7.5e-36 122.2 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 CCC72147.1 - 5e-29 99.8 0.1 1.3e-28 98.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 CCC72147.1 - 1.2e-13 51.0 0.0 2.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase NMO PF03060.10 CCC72147.1 - 0.003 16.7 0.3 0.053 12.6 0.2 2.6 1 1 0 1 1 1 1 Nitronate monooxygenase SUR7 PF06687.7 CCC72148.1 - 1.9e-16 60.2 14.1 2.6e-15 56.5 9.8 2.6 1 1 0 1 1 1 1 SUR7/PalI family DUF2101 PF09874.4 CCC72148.1 - 8 5.8 11.6 0.42 10.0 0.2 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) SUR7 PF06687.7 CCC72149.1 - 1.2e-36 126.2 16.1 1.4e-36 126.0 11.2 1.0 1 0 0 1 1 1 1 SUR7/PalI family PMP22_Claudin PF00822.15 CCC72149.1 - 0.13 11.8 9.1 0.21 11.2 0.4 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family EAP30 PF04157.11 CCC72150.1 - 1.6e-37 128.8 0.4 1.6e-37 128.8 0.3 2.0 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 CCC72150.1 - 8.1e-34 115.2 0.1 2.3e-33 113.8 0.1 1.9 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 TFIIH_BTF_p62_N PF08567.6 CCC72150.1 - 0.0022 17.5 1.0 0.35 10.5 0.2 2.8 2 0 0 2 2 2 1 TFIIH p62 subunit, N-terminal domain DZR PF12773.2 CCC72150.1 - 0.01 15.6 1.6 0.01 15.6 1.1 2.3 1 1 1 2 2 2 0 Double zinc ribbon GRAM PF02893.15 CCC72150.1 - 0.017 14.6 0.0 0.047 13.2 0.0 1.8 1 0 0 1 1 1 0 GRAM domain zf-RanBP PF00641.13 CCC72150.1 - 0.02 13.9 10.6 0.19 10.8 1.0 3.1 2 1 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 CCC72150.1 - 0.024 14.1 12.2 0.034 13.7 0.0 2.9 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger Rubredoxin PF00301.15 CCC72150.1 - 0.12 12.3 1.7 2 8.3 0.0 3.3 3 0 0 3 3 3 0 Rubredoxin Cas_CXXC_CXXC PF09706.5 CCC72150.1 - 0.33 11.1 11.8 0.2 11.8 2.3 3.3 2 1 1 3 3 3 0 CRISPR-associated protein (Cas_CXXC_CXXC) zf-DHHC PF01529.15 CCC72150.1 - 0.56 9.5 8.5 1.7 7.9 5.9 1.9 1 1 0 1 1 1 0 DHHC palmitoyltransferase FYDLN_acid PF09538.5 CCC72150.1 - 2.4 8.7 6.3 0.48 11.0 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) CDC73 PF05179.9 CCC72151.1 - 9.2e-73 244.9 1.8 1.5e-72 244.2 1.1 1.4 1 1 1 2 2 2 1 RNA pol II accessory factor, Cdc73 family OB_NTP_bind PF07717.11 CCC72152.1 - 8.1e-19 67.5 0.0 2.6e-18 65.9 0.0 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.17 CCC72152.1 - 7e-14 51.6 2.6 2.3e-13 50.0 1.8 2.0 1 0 0 1 1 1 1 RWD domain HA2 PF04408.18 CCC72152.1 - 8.5e-12 44.9 1.6 1.9e-11 43.8 0.0 2.4 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.24 CCC72152.1 - 1.7e-10 40.6 0.8 5.9e-10 38.8 0.4 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 CCC72152.1 - 5.7e-10 38.9 0.1 1.6e-09 37.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 CCC72152.1 - 8.4e-06 25.1 0.3 0.0012 18.1 0.0 3.2 3 0 0 3 3 3 1 PhoH-like protein AAA_22 PF13401.1 CCC72152.1 - 2.5e-05 24.4 0.0 0.00011 22.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 CCC72152.1 - 0.00083 19.0 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_29 PF13555.1 CCC72152.1 - 0.0011 18.5 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 CCC72152.1 - 0.0014 17.5 0.0 0.0028 16.6 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 CCC72152.1 - 0.0031 17.0 0.0 0.0068 15.9 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family UBA PF00627.26 CCC72152.1 - 0.0041 16.9 0.2 0.011 15.5 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain AAA_25 PF13481.1 CCC72152.1 - 0.0042 16.4 0.0 0.011 15.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zot PF05707.7 CCC72152.1 - 0.012 15.1 0.0 0.04 13.3 0.0 1.9 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) DND1_DSRM PF14709.1 CCC72152.1 - 0.016 15.5 0.0 0.057 13.7 0.0 2.0 2 0 0 2 2 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 KaiC PF06745.8 CCC72152.1 - 0.02 14.0 0.1 0.074 12.1 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.1 CCC72152.1 - 0.023 14.7 0.0 0.14 12.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 CCC72152.1 - 0.054 13.2 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain Sigma54_activat PF00158.21 CCC72152.1 - 0.12 11.8 0.1 0.82 9.1 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain Aldo_ket_red PF00248.16 CCC72153.1 - 3.8e-63 212.9 0.1 4.6e-63 212.6 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Oxidored_FMN PF00724.15 CCC72154.1 - 3.1e-130 434.1 0.0 3.6e-130 433.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Amidohydro_4 PF13147.1 CCC72155.1 - 5e-09 36.5 0.0 6.3e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 CCC72155.1 - 4.2e-07 29.8 0.1 1.9e-06 27.6 0.0 2.0 2 1 1 3 3 3 1 Amidohydrolase Proteasom_Rpn13 PF04683.8 CCC72156.1 - 1.2e-19 70.1 0.0 1.8e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor Ded_cyto PF06920.8 CCC72157.1 - 1.4e-19 70.0 0.1 1.4e-18 66.8 0.0 2.6 2 0 0 2 2 2 1 Dedicator of cytokinesis DNA_repr_REX1B PF14966.1 CCC72157.1 - 0.015 15.6 1.2 6.8 7.1 0.0 3.6 3 0 0 3 3 3 0 DNA repair REX1-B PP-binding PF00550.20 CCC72158.1 - 6.7e-12 45.5 0.3 9.8e-12 44.9 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 CCC72158.1 - 8.3e-08 32.1 0.7 1.2e-07 31.6 0.5 1.3 1 0 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 CCC72158.1 - 0.0061 16.6 0.1 0.01 15.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1493) APG17 PF04108.7 CCC72159.1 - 2.8e-91 306.3 22.5 3.1e-91 306.2 15.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg17 KorB PF08535.5 CCC72159.1 - 0.0042 17.2 0.1 0.013 15.6 0.1 1.8 1 0 0 1 1 1 1 KorB domain Fib_alpha PF08702.5 CCC72159.1 - 0.0088 16.1 7.3 0.0088 16.1 5.1 4.3 2 1 3 5 5 5 1 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 CCC72159.1 - 0.02 14.7 5.7 0.03 14.1 0.3 3.3 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DASH_Dam1 PF08653.5 CCC72159.1 - 0.27 11.0 1.9 6.6 6.5 0.0 3.4 2 2 1 3 3 3 0 DASH complex subunit Dam1 Myb_DNA-bind_5 PF13873.1 CCC72159.1 - 0.51 10.2 5.8 1.2 9.0 0.0 3.3 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain G-patch PF01585.18 CCC72160.1 - 5.2e-12 45.3 4.5 1e-11 44.4 3.1 1.5 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 CCC72160.1 - 1e-05 25.2 0.3 3.1e-05 23.7 0.2 1.9 1 0 0 1 1 1 1 DExH-box splicing factor binding site EHN PF06441.7 CCC72160.1 - 0.65 9.9 4.4 0.37 10.7 0.4 2.6 3 0 0 3 3 3 0 Epoxide hydrolase N terminus CHCH PF06747.8 CCC72161.1 - 4.6e-08 32.7 3.8 8.2e-08 31.9 2.6 1.4 1 0 0 1 1 1 1 CHCH domain Spore_coat_CotO PF14153.1 CCC72161.1 - 5.1 6.4 18.5 2.9 7.3 3.3 2.2 2 0 0 2 2 2 0 Spore coat protein CotO Ycf1 PF05758.7 CCC72161.1 - 5.3 4.6 8.7 7.8 4.0 6.0 1.3 1 1 0 1 1 1 0 Ycf1 CNH PF00780.17 CCC72162.1 - 4.2e-13 49.3 0.4 9.9e-13 48.1 0.3 1.6 1 1 0 1 1 1 1 CNH domain PH PF00169.24 CCC72162.1 - 3.2e-12 46.5 1.1 1.3e-11 44.6 0.1 2.4 2 0 0 2 2 2 1 PH domain PH_5 PF15405.1 CCC72162.1 - 6.5e-08 32.6 0.1 3.6e-05 23.7 0.1 3.0 2 0 0 2 2 2 2 Pleckstrin homology domain RhoGEF PF00621.15 CCC72162.1 - 1.2e-06 28.4 0.1 3.9e-06 26.8 0.1 1.9 1 0 0 1 1 1 1 RhoGEF domain Zip PF02535.17 CCC72162.1 - 0.44 9.5 2.8 0.73 8.7 1.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Aa_trans PF01490.13 CCC72163.1 - 1.1e-79 267.9 34.4 1.2e-79 267.7 23.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein zf-C3HC4 PF00097.20 CCC72164.1 - 2.5e-07 30.2 5.1 6.8e-07 28.8 3.5 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 CCC72164.1 - 5.6e-07 29.2 4.6 9.5e-07 28.5 3.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 CCC72164.1 - 5.8e-07 29.1 5.7 1.2e-06 28.1 3.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 CCC72164.1 - 1.9e-06 27.7 8.1 4.2e-06 26.6 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 CCC72164.1 - 4.3e-06 26.3 4.5 7.9e-06 25.4 3.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 CCC72164.1 - 9.9e-05 21.9 4.5 0.0003 20.4 3.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 CCC72164.1 - 0.0013 18.5 9.2 0.0049 16.7 6.4 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING FYVE PF01363.16 CCC72164.1 - 0.22 11.4 2.9 0.71 9.8 2.0 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-MIZ PF02891.15 CCC72164.1 - 0.28 10.7 6.7 1 8.9 4.6 2.0 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.3 CCC72164.1 - 0.32 10.5 5.3 0.95 9.0 3.7 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2004 PF09406.5 CCC72164.1 - 0.83 9.7 6.4 0.23 11.5 0.4 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2004) DUF1900 PF08954.6 CCC72165.1 - 6.8e-49 164.8 0.0 1.5e-48 163.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 CCC72165.1 - 6e-32 109.0 0.9 1.2e-31 108.1 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 CCC72165.1 - 5.4e-24 83.1 7.2 4.2e-07 29.5 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Nup160 PF11715.3 CCC72165.1 - 1e-08 33.8 0.1 1.3e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 SEN1_N PF12726.2 CCC72166.1 - 3.9e-222 739.3 23.7 5.4e-222 738.8 16.4 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 CCC72166.1 - 2.7e-68 230.0 0.2 2.7e-68 230.0 0.1 3.0 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 CCC72166.1 - 1.7e-64 216.8 0.1 1.7e-64 216.8 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 CCC72166.1 - 9.9e-11 41.2 0.0 3.4e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 CCC72166.1 - 4.1e-07 29.7 0.0 0.00024 20.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.1 CCC72166.1 - 0.0089 16.1 0.0 0.03 14.4 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_25 PF13481.1 CCC72166.1 - 0.25 10.6 0.0 0.56 9.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain BAAT_C PF08840.6 CCC72167.1 - 0.093 12.4 4.9 0.077 12.6 1.5 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Tox-ART-HYD1 PF15633.1 CCC72167.1 - 1.6 9.6 6.8 0.71 10.7 1.6 2.6 1 1 1 2 2 2 0 HYD1 signature containing ADP-ribosyltransferase Metallophos PF00149.23 CCC72168.1 - 6e-45 153.1 0.4 9.1e-45 152.5 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase WGG PF10273.4 CCC72169.1 - 2.9e-30 104.1 0.2 5.9e-30 103.1 0.2 1.5 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 TFIIF_alpha PF05793.7 CCC72169.1 - 0.11 10.8 6.7 0.13 10.5 4.7 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Hid1 PF12722.2 CCC72170.1 - 8.5e-172 573.0 81.9 1.4e-171 572.2 56.8 1.4 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein RNR_inhib PF08591.5 CCC72171.1 - 4.1e-12 46.8 0.4 6.7e-12 46.1 0.3 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Rop-like PF05082.8 CCC72172.1 - 0.0044 16.4 0.6 0.011 15.2 0.4 1.7 1 1 0 1 1 1 1 Rop-like Aminotran_3 PF00202.16 CCC72173.1 - 2e-107 358.9 0.0 2.4e-107 358.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 CCC72173.1 - 5.6e-07 28.9 0.0 9.1e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 CCC72173.1 - 0.16 10.9 0.0 0.49 9.3 0.0 1.7 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family LSM PF01423.17 CCC72174.1 - 6.2e-19 67.3 0.1 7.5e-19 67.0 0.0 1.0 1 0 0 1 1 1 1 LSM domain MRP-L47 PF06984.8 CCC72176.1 - 4.9e-24 84.0 2.5 6.1e-23 80.5 0.3 3.0 4 0 0 4 4 4 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Sec39 PF08314.6 CCC72177.1 - 1.6e-114 383.4 27.8 2.1e-114 382.9 19.3 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ribosomal_S3Ae PF01015.13 CCC72178.1 - 5.4e-81 270.5 7.4 6.4e-81 270.3 5.1 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Inhibitor_I9 PF05922.11 CCC72178.1 - 0.042 14.4 0.1 0.095 13.2 0.0 1.8 1 0 0 1 1 1 0 Peptidase inhibitor I9 Abhydro_lipase PF04083.11 CCC72178.1 - 0.043 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region Ras PF00071.17 CCC72179.1 - 2.5e-29 101.7 0.1 3e-29 101.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 CCC72179.1 - 7.3e-19 68.4 0.0 1.1e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 CCC72179.1 - 8.1e-08 31.6 0.3 9.8e-08 31.4 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 CCC72179.1 - 1.4e-06 27.7 0.0 1.7e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 CCC72179.1 - 7.9e-05 22.1 0.1 0.00047 19.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 CCC72179.1 - 0.0014 18.1 1.1 0.04 13.4 0.6 2.7 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 CCC72179.1 - 0.0038 17.1 0.1 0.0091 15.9 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 CCC72179.1 - 0.06 12.5 0.0 0.073 12.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NPHI_C PF08469.5 CCC72179.1 - 0.09 12.6 0.2 0.27 11.1 0.1 1.8 1 1 0 1 1 1 0 Nucleoside triphosphatase I C-terminal FeoB_N PF02421.13 CCC72179.1 - 0.11 11.7 0.2 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 Ferrous iron transport protein B BAH PF01426.13 CCC72180.1 - 3.2e-15 55.9 0.0 3.2e-15 55.9 0.0 2.1 3 0 0 3 3 3 1 BAH domain AAA PF00004.24 CCC72180.1 - 4.2e-10 39.9 0.0 1.6e-09 38.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 CCC72180.1 - 1.4e-07 31.7 0.0 4.4e-07 30.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 CCC72180.1 - 1.6e-06 27.9 0.1 1.6e-06 27.9 0.1 3.0 3 1 1 4 4 4 1 Archaeal ATPase AAA_16 PF13191.1 CCC72180.1 - 3.7e-06 27.0 3.3 3.1e-05 24.0 0.0 3.5 2 2 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 CCC72180.1 - 0.0017 18.0 0.0 0.0042 16.7 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PIF1 PF05970.9 CCC72180.1 - 0.0044 16.0 0.0 0.021 13.8 0.0 1.9 2 0 0 2 2 2 1 PIF1-like helicase AAA_17 PF13207.1 CCC72180.1 - 0.034 14.9 1.0 0.67 10.7 0.0 3.2 2 0 0 2 2 2 0 AAA domain SUR7 PF06687.7 CCC72181.1 - 1e-10 41.5 10.1 1.5e-10 41.0 7.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family RNR_inhib PF08591.5 CCC72183.1 - 4.1e-12 46.8 0.4 6.7e-12 46.1 0.3 1.3 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor COPIIcoated_ERV PF07970.7 CCC72184.1 - 1.1e-28 100.3 0.4 1.9e-28 99.6 0.3 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 CCC72184.1 - 9.6e-20 70.3 0.1 9.6e-20 70.3 0.1 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Phosphodiest PF01663.17 CCC72185.1 - 0.027 13.7 0.0 0.043 13.1 0.0 1.2 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase DUF3384 PF11864.3 CCC72185.1 - 0.063 11.7 0.9 0.099 11.0 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) zf-C3HC PF07967.8 CCC72185.1 - 0.3 10.8 3.5 0.26 11.0 0.3 2.0 1 1 1 2 2 2 0 C3HC zinc finger-like LXG PF04740.7 CCC72186.1 - 0.011 15.5 1.9 0.02 14.6 1.3 1.4 1 0 0 1 1 1 0 LXG domain of WXG superfamily vATP-synt_AC39 PF01992.11 CCC72188.1 - 1.3e-85 287.5 0.3 1.4e-85 287.3 0.2 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Ribosomal_L6e PF01159.14 CCC72189.1 - 5.5e-38 129.5 2.9 8.2e-38 128.9 2.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e MCPVI PF02993.9 CCC72189.1 - 0.057 13.5 0.7 0.057 13.5 0.5 1.4 2 0 0 2 2 2 0 Minor capsid protein VI Med25 PF11232.3 CCC72189.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.5 2 0 0 2 2 2 0 Mediator complex subunit 25 PTOV activation and synapsin 2 Piwi PF02171.12 CCC72190.1 - 2.1e-67 227.2 0.1 3.1e-67 226.6 0.1 1.3 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 CCC72190.1 - 1.8e-05 24.0 0.0 4.8e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 PAZ domain FKBP_C PF00254.23 CCC72191.1 - 6.7e-28 96.5 0.5 4.9e-27 93.7 0.0 2.6 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase TFR_dimer PF04253.10 CCC72192.1 - 6.8e-10 38.5 0.0 1.6e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 CCC72192.1 - 3.5e-09 36.6 0.0 5.9e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 CCC72192.1 - 0.011 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 PA domain zf-H2C2_2 PF13465.1 CCC72193.1 - 6.5e-06 26.1 11.0 2.7e-05 24.2 3.7 2.5 2 0 0 2 2 2 1 Zinc-finger double domain AF1Q PF15017.1 CCC72193.1 - 0.0041 16.9 0.4 0.0041 16.9 0.3 2.3 2 0 0 2 2 2 1 Drug resistance and apoptosis regulator Lar_restr_allev PF14354.1 CCC72193.1 - 0.058 13.7 0.2 0.058 13.7 0.1 1.8 2 0 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1 PF03811.8 CCC72193.1 - 0.12 11.8 3.8 0.28 10.7 2.6 1.6 1 0 0 1 1 1 0 InsA N-terminal domain zf-C2H2 PF00096.21 CCC72193.1 - 0.15 12.4 8.2 2.4 8.6 0.4 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 CCC72193.1 - 1.9 8.9 6.1 4.2 7.9 0.3 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Methyltransf_16 PF10294.4 CCC72194.1 - 4.4e-24 84.8 0.3 6.8e-24 84.2 0.2 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 CCC72194.1 - 0.0027 18.2 0.0 0.0051 17.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Hanta_G2 PF01561.11 CCC72194.1 - 0.014 13.8 0.5 0.023 13.1 0.2 1.4 1 1 0 1 1 1 0 Hantavirus glycoprotein G2 MTS PF05175.9 CCC72194.1 - 0.045 13.1 0.0 0.074 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_31 PF13847.1 CCC72194.1 - 0.074 12.6 0.1 0.17 11.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Topoisom_I PF01028.15 CCC72194.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.5 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, catalytic core Glyco_hydro_47 PF01532.15 CCC72195.1 - 3.4e-134 447.9 0.9 3.9e-134 447.7 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 IBN_N PF03810.14 CCC72196.1 - 2e-18 66.0 0.0 2.3e-16 59.4 0.0 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain Utp12 PF04003.7 CCC72197.1 - 0.00015 21.5 0.4 0.00028 20.7 0.3 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family GYD PF08734.6 CCC72197.1 - 0.085 12.5 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 GYD domain Pribosyltran PF00156.22 CCC72198.1 - 2e-13 50.1 1.2 1.6e-12 47.1 0.8 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain TMF_TATA_bd PF12325.3 CCC72199.1 - 6.5e-38 129.1 60.1 7.5e-35 119.2 12.8 5.7 3 1 1 5 5 5 3 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 CCC72199.1 - 4.8e-13 48.7 91.4 1.1e-11 44.4 5.3 8.6 3 3 5 8 8 7 4 TATA element modulatory factor 1 DNA binding IncA PF04156.9 CCC72199.1 - 1.6e-06 27.8 69.9 0.049 13.2 11.1 4.5 2 1 2 4 4 4 4 IncA protein ERM PF00769.14 CCC72199.1 - 4.1e-05 23.2 4.2 4.1e-05 23.2 2.9 4.1 4 1 0 4 4 4 1 Ezrin/radixin/moesin family Fez1 PF06818.10 CCC72199.1 - 0.00028 20.9 38.9 0.0014 18.7 6.7 3.4 3 0 0 3 3 3 2 Fez1 Myosin_tail_1 PF01576.14 CCC72199.1 - 0.02 12.6 63.7 0.0091 13.7 8.5 3.3 3 0 0 3 3 3 0 Myosin tail DUF3138 PF11336.3 CCC72199.1 - 0.039 12.1 8.1 0.41 8.7 0.6 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3138) AvrPto PF11592.3 CCC72199.1 - 0.042 13.6 4.9 2.4 7.9 0.0 4.6 5 0 0 5 5 5 0 Central core of the bacterial effector protein AvrPto DUF848 PF05852.6 CCC72199.1 - 0.092 12.5 57.9 0.31 10.8 6.7 5.6 2 2 4 6 6 6 0 Gammaherpesvirus protein of unknown function (DUF848) CENP-F_leu_zip PF10473.4 CCC72199.1 - 0.15 11.9 80.3 0.038 13.8 9.8 6.0 2 1 3 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.4 CCC72199.1 - 0.17 10.7 61.1 0.34 9.7 8.2 4.3 2 1 1 4 4 4 0 UV radiation resistance protein and autophagy-related subunit 14 Lebercilin PF15619.1 CCC72199.1 - 0.4 10.0 70.9 0.04 13.3 8.2 4.3 4 0 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease ATG16 PF08614.6 CCC72199.1 - 0.52 10.1 81.3 0.037 13.8 13.0 5.3 2 1 3 5 5 5 0 Autophagy protein 16 (ATG16) Reo_sigmaC PF04582.7 CCC72199.1 - 0.82 8.7 42.1 0.041 13.0 3.9 4.1 2 2 2 4 4 4 0 Reovirus sigma C capsid protein HOOK PF05622.7 CCC72199.1 - 3.2 5.4 61.7 0.053 11.3 7.6 4.2 3 1 1 4 4 4 0 HOOK protein DUF3584 PF12128.3 CCC72199.1 - 4.3 4.5 62.4 0.18 9.0 19.7 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) GAS PF13851.1 CCC72199.1 - 6.8 5.8 79.6 0.84 8.7 14.8 4.7 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.7 CCC72199.1 - 9.5 6.0 65.9 1.7 8.4 5.9 6.2 2 2 4 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Muted PF14942.1 CCC72200.1 - 0.0016 18.3 2.5 0.0016 18.3 1.7 2.2 2 1 0 2 2 2 1 Organelle biogenesis, Muted-like protein SseB PF07179.7 CCC72200.1 - 0.017 14.9 0.0 3 7.6 0.0 2.4 2 0 0 2 2 2 0 SseB protein N-terminal domain CPL PF08144.6 CCC72200.1 - 0.066 13.0 0.2 0.28 11.0 0.0 2.0 1 1 1 2 2 2 0 CPL (NUC119) domain DUF2664 PF10867.3 CCC72200.1 - 0.24 12.0 2.0 0.57 10.8 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2664) DUF2951 PF11166.3 CCC72200.1 - 0.63 9.9 8.7 4.5 7.1 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Vps54 PF07928.7 CCC72200.1 - 2.3 8.3 7.0 0.87 9.7 0.4 2.8 3 1 1 4 4 4 0 Vps54-like protein zf-Tim10_DDP PF02953.10 CCC72201.1 - 1.2e-20 72.5 4.1 1.5e-20 72.2 2.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF1767 PF08585.7 CCC72201.1 - 0.0027 17.9 1.1 0.0058 16.8 0.4 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF1767) Torsin PF06309.6 CCC72201.1 - 0.0047 16.8 0.0 0.0054 16.6 0.0 1.1 1 0 0 1 1 1 1 Torsin DUF842 PF05811.8 CCC72201.1 - 0.0069 15.8 3.4 0.0082 15.6 2.4 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) Spore-coat_CotZ PF10612.4 CCC72201.1 - 0.042 13.7 3.8 0.054 13.3 2.4 1.4 1 1 0 1 1 1 0 Spore coat protein Z DUF2454 PF10521.4 CCC72202.1 - 6e-56 189.5 10.0 7.8e-56 189.1 6.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Aminotran_4 PF01063.14 CCC72203.1 - 6.9e-30 104.2 0.0 8.5e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Ribosomal_S4e PF00900.15 CCC72204.1 - 8.7e-33 111.8 1.8 4.7e-32 109.4 0.7 2.1 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 CCC72204.1 - 6.9e-20 70.6 4.4 1.4e-19 69.6 3.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 CCC72204.1 - 1.4e-07 30.7 0.5 2.6e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 S4 domain KOW PF00467.24 CCC72204.1 - 1.1e-05 24.8 1.5 1.1e-05 24.8 1.0 3.4 4 0 0 4 4 4 1 KOW motif PMT PF02366.13 CCC72205.1 - 1.3e-74 250.6 23.9 1.3e-74 250.6 16.6 2.0 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 CCC72205.1 - 4.6e-19 68.7 0.0 7.1e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 MIR domain NUDIX PF00293.23 CCC72206.1 - 2.8e-06 27.0 0.0 4.6e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HECT_2 PF09814.4 CCC72207.1 - 1.7e-66 224.3 0.3 2.1e-66 224.0 0.2 1.0 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Yippee-Mis18 PF03226.9 CCC72207.1 - 0.077 13.0 0.1 5.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly AfsA PF03756.8 CCC72208.1 - 0.1 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 A-factor biosynthesis hotdog domain DUF3608 PF12257.3 CCC72209.1 - 8e-141 467.8 3.6 1.4e-140 467.0 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 CCC72209.1 - 1.6e-26 91.8 0.8 1.6e-26 91.8 0.6 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) NIR_SIR PF01077.17 CCC72210.1 - 8.5e-50 168.1 0.0 3.1e-45 153.3 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 CCC72210.1 - 3.4e-28 97.0 0.0 5.4e-13 48.3 0.0 2.9 3 0 0 3 3 3 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 CCC72210.1 - 5.3e-26 91.3 0.0 1.1e-25 90.2 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin Sir1 PF11603.3 CCC72211.1 - 6.4e-29 100.6 8.4 2e-15 57.0 0.0 4.0 3 1 0 3 3 3 3 Regulatory protein Sir1 Hyphal_reg_CWP PF11765.3 CCC72212.1 - 3.1e-46 157.6 12.9 3.1e-46 157.6 9.0 3.7 3 2 1 4 4 4 1 Hyphally regulated cell wall protein N-terminal PRP21_like_P PF12230.3 CCC72213.1 - 1.5e-32 112.9 13.9 3.7e-31 108.4 9.7 2.0 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 CCC72213.1 - 0.0036 16.9 1.8 0.014 15.0 0.4 2.7 2 1 0 2 2 2 1 Surp module Bromodomain PF00439.20 CCC72213.1 - 0.13 12.2 4.5 1.3 8.9 0.0 3.1 2 1 0 2 2 2 0 Bromodomain ArfGap PF01412.13 CCC86749.1 - 2.6e-30 104.6 3.7 2.6e-30 104.6 2.6 3.8 3 1 0 4 4 4 2 Putative GTPase activating protein for Arf PH PF00169.24 CCC86749.1 - 1.3e-05 25.3 6.2 6.7e-05 23.0 4.3 2.3 1 0 0 1 1 1 1 PH domain PX PF00787.19 CCC86750.1 - 1.7e-24 85.7 3.7 2e-24 85.5 0.2 2.5 3 0 0 3 3 2 1 PX domain Vps5 PF09325.5 CCC86750.1 - 1.5e-05 24.3 17.7 0.00081 18.7 4.4 2.5 2 1 0 2 2 2 2 Vps5 C terminal like PilJ PF13675.1 CCC86750.1 - 0.018 15.3 1.9 0.22 11.8 0.1 3.0 2 1 1 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term Vps51 PF08700.6 CCC86750.1 - 0.026 14.3 0.4 0.026 14.3 0.2 3.5 4 1 1 5 5 4 0 Vps51/Vps67 DUF1732 PF08340.6 CCC86750.1 - 0.034 13.9 2.1 0.068 13.0 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1732) DUF2316 PF10078.4 CCC86750.1 - 0.037 14.0 0.6 0.42 10.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Dor1 PF04124.7 CCC86750.1 - 0.21 10.0 8.2 0.028 12.9 0.9 2.2 2 0 0 2 2 2 0 Dor1-like family DASH_Dad2 PF08654.5 CCC86750.1 - 0.32 11.0 3.4 0.43 10.6 0.4 2.6 2 0 0 2 2 2 0 DASH complex subunit Dad2 FlaC_arch PF05377.6 CCC86750.1 - 0.43 10.5 12.7 0.14 12.0 0.2 3.7 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) Nup54 PF13874.1 CCC86750.1 - 0.49 10.0 5.2 0.33 10.5 0.1 2.8 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Atg14 PF10186.4 CCC86750.1 - 0.57 9.0 9.1 2.5 6.9 2.3 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3552 PF12072.3 CCC86750.1 - 1.3 8.2 14.8 0.04 13.1 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) DUF4446 PF14584.1 CCC86750.1 - 1.5 8.6 8.2 1.6 8.5 0.8 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) IncA PF04156.9 CCC86750.1 - 2.3 7.7 16.0 0.14 11.7 3.5 2.3 1 1 1 2 2 1 0 IncA protein NPV_P10 PF05531.7 CCC86750.1 - 2.7 8.2 12.1 1.2 9.4 0.6 4.0 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein KSR1-SAM PF13543.1 CCC86750.1 - 3.8 7.3 7.1 0.33 10.7 0.4 2.5 3 1 0 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 DUF1664 PF07889.7 CCC86750.1 - 3.8 7.3 8.8 2.1 8.1 1.9 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin PF02996.12 CCC86750.1 - 4.3 7.0 13.3 2.1 8.0 0.7 3.5 3 0 0 3 3 3 0 Prefoldin subunit DUF4618 PF15397.1 CCC86750.1 - 4.7 6.4 21.0 0.19 11.0 1.7 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4618) Synaptobrevin PF00957.16 CCC86750.1 - 5.2 6.7 8.9 14 5.3 0.5 2.6 2 0 0 2 2 2 0 Synaptobrevin Remorin_C PF03763.8 CCC86750.1 - 5.8 6.4 9.3 10 5.6 1.4 2.6 2 1 0 2 2 2 0 Remorin, C-terminal region TMF_TATA_bd PF12325.3 CCC86750.1 - 6.3 6.5 14.3 0.064 12.9 0.4 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF3571 PF12095.3 CCC86750.1 - 7.2 6.9 7.9 0.55 10.4 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3571) Brr6_like_C_C PF10104.4 CCC86751.1 - 2.2e-42 143.7 7.1 3.5e-42 143.1 4.9 1.3 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain GHBP PF12772.2 CCC86751.1 - 0.033 13.6 4.6 0.027 13.9 1.8 1.7 1 1 0 1 1 1 0 Growth hormone receptor binding